M-phase inducer phosphatase

Overview
NameM-phase inducer phosphatase
Smed IDSMED30033670
Length (bp)1108
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of M-phase inducer phosphatase (SMED30033670) t-SNE clustered cells

Violin plots show distribution of expression levels for M-phase inducer phosphatase (SMED30033670) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033670

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30033670SMESG000025390.1 Contig40640newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30033670SMESG000025390.1 Contig40640uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Match: CDC25C (cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727])

HSP 1 Score: 86.6557 bits (213), Expect = 6.243e-19
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  129 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 222
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Match: CDC25C (cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727])

HSP 1 Score: 88.1965 bits (217), Expect = 1.265e-18
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  297 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 390
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Match: CDC25C (cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727])

HSP 1 Score: 87.8113 bits (216), Expect = 1.440e-18
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  254 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 347
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Match: CDC25C (cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727])

HSP 1 Score: 87.8113 bits (216), Expect = 1.440e-18
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  254 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 347
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Match: CDC25C (cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727])

HSP 1 Score: 88.1965 bits (217), Expect = 1.455e-18
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  327 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 420
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Match: cdc-25.1 (M-phase inducer phosphatase cdc-25.1 [Source:UniProtKB/Swiss-Prot;Acc:O44552])

HSP 1 Score: 83.1889 bits (204), Expect = 3.350e-17
Identity = 42/116 (36.21%), Postives = 63/116 (54.31%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y I+D RFPFE+ GGH+ GA+NLF   D  +  F P+  +  S ++ +                   IF+CE+S  R P MA  +R IDR  N   YPH+ YP++++L  GY++ +
Sbjct:  309 YIIVDCRFPFEYKGGHVKGAINLFR-HDKIKPIFFPENGEASSFQNRVP------------------IFYCEYSQKRGPTMAHAVRSIDRVLNELRYPHVEYPEMYLLDYGYKSLW 405
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Match: cdc-25.1 (M-phase inducer phosphatase cdc-25.1 [Source:UniProtKB/Swiss-Prot;Acc:O44552])

HSP 1 Score: 83.1889 bits (204), Expect = 3.350e-17
Identity = 42/116 (36.21%), Postives = 63/116 (54.31%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y I+D RFPFE+ GGH+ GA+NLF   D  +  F P+  +  S ++ +                   IF+CE+S  R P MA  +R IDR  N   YPH+ YP++++L  GY++ +
Sbjct:  309 YIIVDCRFPFEYKGGHVKGAINLFR-HDKIKPIFFPENGEASSFQNRVP------------------IFYCEYSQKRGPTMAHAVRSIDRVLNELRYPHVEYPEMYLLDYGYKSLW 405
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Match: cdc-25.3 (M-phase inducer phosphatase cdc-25.3 [Source:UniProtKB/Swiss-Prot;Acc:P30634])

HSP 1 Score: 81.6481 bits (200), Expect = 3.804e-17
Identity = 44/116 (37.93%), Postives = 59/116 (50.86%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y +ID R+ +E+NGGHI GA +LF P     +FF  D  K                       N   IF+CE+S  R P MA  LR +DR  N + YP   Y +I++L+GGY+ FY
Sbjct:  140 YILIDCRYDYEYNGGHIKGAQSLFNPETAADFFFNKDGSK---------------------KINRIPIFYCEYSQKRGPTMANNLREVDRKLNSNIYPRCDYEEIYLLEGGYKNFY 234
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Match: cdc-25.2 (M-phase inducer phosphatase cdc-25.2 [Source:UniProtKB/Swiss-Prot;Acc:O44628])

HSP 1 Score: 73.9442 bits (180), Expect = 3.097e-14
Identity = 42/116 (36.21%), Postives = 60/116 (51.72%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y +ID R+P+E+N GHI  A+N F  + V + F+  +  K                       N   IF+CEFS AR PKMA  LR +DR  N++ YP   Y ++++L  GYR F+
Sbjct:  247 YILIDCRYPYEYNRGHIKNAINHFDRVTVSKIFYDENGRK---------------------RCNKIPIFYCEFSQARGPKMAYALRQVDRELNVNHYPKCDYEEMYVLDLGYRNFF 341
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Match: cdc-25.2 (M-phase inducer phosphatase cdc-25.2 [Source:UniProtKB/Swiss-Prot;Acc:O44628])

HSP 1 Score: 73.559 bits (179), Expect = 3.757e-14
Identity = 42/116 (36.21%), Postives = 60/116 (51.72%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y +ID R+P+E+N GHI  A+N F  + V + F+  +  K                       N   IF+CEFS AR PKMA  LR +DR  N++ YP   Y ++++L  GYR F+
Sbjct:  225 YILIDCRYPYEYNRGHIKNAINHFDRVTVSKIFYDENGRK---------------------RCNKIPIFYCEFSQARGPKMAYALRQVDRELNVNHYPKCDYEEMYVLDLGYRNFF 319
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Match: stg (gene:FBgn0003525 transcript:FBtr0085397)

HSP 1 Score: 97.0561 bits (240), Expect = 8.284e-22
Identity = 53/139 (38.13%), Postives = 78/139 (56.12%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            ++ I  + V ++++  ++    +Y IID R+P+EF GGHI GA NL+T   +   F    Q + Q  ++      RNII           IFHCEFSS R PKM+  LR +DR  N + YP L YP+I++L  GY+ F+
Sbjct:  297 LKSISSETVARLLKGEFSDKVASYRIIDCRYPYEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNII-----------IFHCEFSSERGPKMSRFLRNLDRERNTNAYPALHYPEIYLLHNGYKEFF 424
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Match: stg (gene:FBgn0003525 transcript:FBtr0334867)

HSP 1 Score: 97.0561 bits (240), Expect = 8.284e-22
Identity = 53/139 (38.13%), Postives = 78/139 (56.12%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            ++ I  + V ++++  ++    +Y IID R+P+EF GGHI GA NL+T   +   F    Q + Q  ++      RNII           IFHCEFSS R PKM+  LR +DR  N + YP L YP+I++L  GY+ F+
Sbjct:  297 LKSISSETVARLLKGEFSDKVASYRIIDCRYPYEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNII-----------IFHCEFSSERGPKMSRFLRNLDRERNTNAYPALHYPEIYLLHNGYKEFF 424
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Match: twe (gene:FBgn0002673 transcript:FBtr0331444)

HSP 1 Score: 79.7221 bits (195), Expect = 4.297e-16
Identity = 45/116 (38.79%), Postives = 61/116 (52.59%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y IID R+P+EF GGHI GA NL+T   + + F         S+++N  + V                FHCEFSS R PK+   LR  DR  +   YP L YP+++IL  GY+ F+
Sbjct:  269 YEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF-----PTLTSNQENRRIYV----------------FHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFF 363
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Match: twe (gene:FBgn0002673 transcript:FBtr0331445)

HSP 1 Score: 79.7221 bits (195), Expect = 4.297e-16
Identity = 45/116 (38.79%), Postives = 61/116 (52.59%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y IID R+P+EF GGHI GA NL+T   + + F         S+++N  + V                FHCEFSS R PK+   LR  DR  +   YP L YP+++IL  GY+ F+
Sbjct:  269 YEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF-----PTLTSNQENRRIYV----------------FHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFF 363
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Match: twe (gene:FBgn0002673 transcript:FBtr0331446)

HSP 1 Score: 79.7221 bits (195), Expect = 4.297e-16
Identity = 45/116 (38.79%), Postives = 61/116 (52.59%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            Y IID R+P+EF GGHI GA NL+T   + + F         S+++N  + V                FHCEFSS R PK+   LR  DR  +   YP L YP+++IL  GY+ F+
Sbjct:  269 YEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF-----PTLTSNQENRRIYV----------------FHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFF 363
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Zebrafish
Match: cdc25d (cell division cycle 25 homolog d [Source:ZFIN;Acc:ZDB-GENE-090313-74])

HSP 1 Score: 90.5077 bits (223), Expect = 1.055e-19
Identity = 49/142 (34.51%), Postives = 75/142 (52.82%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINL----QKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMN 808
            I    V  ++   +     ++ I+D R+P+E+ GGHI GAVNL+T   V Q      Q   Q       L  R+  +     ++  S   +IFHCEFSS R P + + LR +DR  N+  YP L YP++++L GGY+ F+ +
Sbjct:  204 ISAQTVASLIRGQFGSAVEDFLIVDCRYPYEYQGGHIKGAVNLYTEHQVQQVLH---QASAQVSVSTSRLCGRSASDSLPEDEESPSRKLIIFHCEFSSERGPHLCQYLRRLDRCVNV--YPSLHYPELYLLLGGYKHFHAS 340
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Zebrafish
Match: cdc25b (cell division cycle 25B [Source:ZFIN;Acc:ZDB-GENE-000330-5])

HSP 1 Score: 88.1965 bits (217), Expect = 1.342e-18
Identity = 56/162 (34.57%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            +ID R+P+E+ GGHI GA+NL     +  YF                  +R+ I        + LIFHCEFSS R P+M   +R  DRF N   YP+L YP+++ILKGGY+ F+  +K   +  +Y+  +  +    F+E    F+   +T+  + SKR  Y
Sbjct:  420 VIDCRYPYEYEGGHIKGALNLHQEDQIEDYF------------------LRSPILPDCPKKRVLLIFHCEFSSERGPRMCRYVRERDRFVNE--YPNLHYPELYILKGGYKEFFQIHKAICEPQMYRPMLHEE----FKEDLRKFRLKSRTWAGERSKRDMY 557
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Match: adcy7 (adenylate cyclase 7 [Source:Xenbase;Acc:XB-GENE-1005225])

HSP 1 Score: 90.5077 bits (223), Expect = 5.147e-21
Identity = 51/131 (38.93%), Postives = 68/131 (51.91%), Query Frame = 2 
Query:  410 VKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            + +++   Y      Y I+D R+P+E+ GGHI GA NL+    +   F                     + N     S   LIFHCEFSS RAPK+   LR +DR AN   YPHL YP+++ILKGGY+ FY
Sbjct:   11 LARLLRGGYQDVVQQYQIVDCRYPYEYAGGHIKGAYNLYKEEHISDTF---------------------LKNATHPKSTTLLIFHCEFSSERAPKLCRLLRNLDRNANR--YPHLHYPELYILKGGYKEFY 118
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Match: ENSXETT00000036492.1 (M-phase inducer phosphatase 3-like [Source:NCBI gene;Acc:100497395])

HSP 1 Score: 93.9745 bits (232), Expect = 1.294e-20
Identity = 52/136 (38.24%), Postives = 69/136 (50.74%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            I    + +++   Y      Y I+D R+P+E+ GGHI GA NL+    +   F                     + N     S   LIFHCEFSS RAPK+   LR +DR AN   YPHL YP+++ILKGGY+ FY
Sbjct:  239 ISCTTLARLLRGGYQDVVQQYQIVDCRYPYEYAGGHIKGAYNLYKEEHISDTF---------------------LKNATHPKSTTLLIFHCEFSSERAPKLCRLLRNLDRNANR--YPHLHYPELYILKGGYKEFY 351
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Match: man2b1 (mannosidase, alpha, class 2B, member 1 [Source:Xenbase;Acc:XB-GENE-958698])

HSP 1 Score: 88.1965 bits (217), Expect = 1.779e-18
Identity = 57/162 (35.19%), Postives = 82/162 (50.62%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            IID R+P+E+ GGHI GA+NL    +  +YF                  ++N + +   S  + LIFHCEFSS R P+M + LR  DR  N   YP L+YP+++IL GGY+ F+   K       Y+     D    F+E    F+   +T+  + SKR  Y
Sbjct:  385 IIDCRYPYEYEGGHIQGAINLHMEQEAEEYF------------------LKNPV-MSNGSKRVILIFHCEFSSERGPRMCKFLREKDRDRNE--YPQLYYPELYILHGGYKEFFQKCKTYCTPQTYRPMNHED----FKEDLRKFRMKSRTWAGERSKRELY 521
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Match: man2b1 (mannosidase, alpha, class 2B, member 1 [Source:Xenbase;Acc:XB-GENE-958698])

HSP 1 Score: 88.1965 bits (217), Expect = 1.960e-18
Identity = 57/162 (35.19%), Postives = 82/162 (50.62%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            IID R+P+E+ GGHI GA+NL    +  +YF                  ++N + +   S  + LIFHCEFSS R P+M + LR  DR  N   YP L+YP+++IL GGY+ F+   K       Y+     D    F+E    F+   +T+  + SKR  Y
Sbjct:  383 IIDCRYPYEYEGGHIQGAINLHMEQEAEEYF------------------LKNPV-MSNGSKRVILIFHCEFSSERGPRMCKFLREKDRDRNE--YPQLYYPELYILHGGYKEFFQKCKTYCTPQTYRPMNHED----FKEDLRKFRMKSRTWAGERSKRELY 519
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Match: man2b1 (mannosidase, alpha, class 2B, member 1 [Source:Xenbase;Acc:XB-GENE-958698])

HSP 1 Score: 87.8113 bits (216), Expect = 2.185e-18
Identity = 57/162 (35.19%), Postives = 82/162 (50.62%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            IID R+P+E+ GGHI GA+NL    +  +YF                  ++N + +   S  + LIFHCEFSS R P+M + LR  DR  N   YP L+YP+++IL GGY+ F+   K       Y+     D    F+E    F+   +T+  + SKR  Y
Sbjct:  364 IIDCRYPYEYEGGHIQGAINLHMEQEAEEYF------------------LKNPV-MSNGSKRVILIFHCEFSSERGPRMCKFLREKDRDRNE--YPQLYYPELYILHGGYKEFFQKCKTYCTPQTYRPMNHED----FKEDLRKFRMKSRTWAGERSKRELY 500
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Match: Cdc25c (cell division cycle 25C [Source:MGI Symbol;Acc:MGI:88350])

HSP 1 Score: 85.5001 bits (210), Expect = 8.843e-18
Identity = 46/136 (33.82%), Postives = 72/136 (52.94%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            I  D V  ++   +      + IID R+P+E+ GGHI+GA+NL +  ++ ++F                  +R  +        + ++F CEFSS R P+M   LR  DR   L+ YP L+YP+++ILKGGYR F+
Sbjct:  278 ISPDTVAALLSGKFQSVIERFYIIDCRYPYEYLGGHILGALNLHSQKELHEFF------------------LRKPVVPLDIQKRVIIVFLCEFSSERGPRMCRSLREKDR--ALNQYPALYYPELYILKGGYRDFF 393
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Match: Cdc25b (cell division cycle 25B [Source:MGI Symbol;Acc:MGI:99701])

HSP 1 Score: 85.1149 bits (209), Expect = 1.633e-17
Identity = 46/120 (38.33%), Postives = 66/120 (55.00%), Query Frame = 2 
Query:  452 NYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNN 811
             + I+D R+P+E+ GGHI  AVNL  PL+                +D    +++  I        + LIFHCEFSS R P+M   +R  DR AN   YP L+YP+++ILKGGY+ F+  +
Sbjct:  430 KFVIVDCRYPYEYEGGHIKNAVNL--PLE----------------RDAETFLLQRPIMPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRAAN--DYPSLYYPEMYILKGGYKEFFPQH 529
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Match: Cdc25b (cell division cycle 25B [Source:MGI Symbol;Acc:MGI:99701])

HSP 1 Score: 85.1149 bits (209), Expect = 1.655e-17
Identity = 46/117 (39.32%), Postives = 65/117 (55.56%), Query Frame = 2 
Query:  452 NYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
             + I+D R+P+E+ GGHI  AVNL  PL+                +D    +++  I        + LIFHCEFSS R P+M   +R  DR AN   YP L+YP+++ILKGGY+ F+
Sbjct:  404 KFVIVDCRYPYEYEGGHIKNAVNL--PLE----------------RDAETFLLQRPIMPCSLDKRIILIFHCEFSSERGPRMCRFIRERDRAAN--DYPSLYYPEMYILKGGYKEFF 500
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Match: Cdc25a (cell division cycle 25A [Source:MGI Symbol;Acc:MGI:103198])

HSP 1 Score: 83.9593 bits (206), Expect = 2.417e-17
Identity = 45/121 (37.19%), Postives = 65/121 (53.72%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKV 817
            + IID R+P+E+ GGHI GAVNL    +V  +      + T    D   ++V               +FHCEFSS R P+M   +R  DR  N   YP L YP++++LKGGY+ F++  +V
Sbjct:  309 FVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKNPIVPT----DGKRVIV---------------VFHCEFSSERGPRMCRYVRERDRLGNE--YPKLHYPELYVLKGGYKEFFLKCQV 408
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Match: Cdc25a (cell division cycle 25A [Source:MGI Symbol;Acc:MGI:103198])

HSP 1 Score: 84.3445 bits (207), Expect = 2.552e-17
Identity = 54/164 (32.93%), Postives = 81/164 (49.39%), Query Frame = 2 
Query:  455 YCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            + IID R+P+E+ GGHI GAVNL    +V  +      + T    D   ++V               +FHCEFSS R P+M   +R  DR  N   YP L YP++++LKGGY+ F++  +   +   Y+     D    F+E    F+   +T+  + SKR  Y
Sbjct:  370 FVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKNPIVPT----DGKRVIV---------------VFHCEFSSERGPRMCRYVRERDRLGNE--YPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHED----FKEDLKKFRTKSRTWAGEKSKREMY 508
[Close]
BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Match: sp|P20483|MPIP_DROME (M-phase inducer phosphatase OS=Drosophila melanogaster OX=7227 GN=stg PE=1 SV=2)

HSP 1 Score: 97.0561 bits (240), Expect = 8.303e-21
Identity = 53/139 (38.13%), Postives = 78/139 (56.12%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            ++ I  + V ++++  ++    +Y IID R+P+EF GGHI GA NL+T   +   F    Q + Q  ++      RNII           IFHCEFSS R PKM+  LR +DR  N + YP L YP+I++L  GY+ F+
Sbjct:  297 LKSISSETVARLLKGEFSDKVASYRIIDCRYPYEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNII-----------IFHCEFSSERGPKMSRFLRNLDRERNTNAYPALHYPEIYLLHNGYKEFF 424
[Close]
BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Match: sp|P23748|MPIP_YEAST (M-phase inducer phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MIH1 PE=1 SV=2)

HSP 1 Score: 92.8189 bits (229), Expect = 2.730e-19
Identity = 56/139 (40.29%), Postives = 73/139 (52.52%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYC-IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMN 808
            I  + +K I++NN      N C IID RF +E+ GGHII +VN+ +  D  +Y F    L + +  +N    +              LI HCEFSS R P +A  LR  DR  N D YP LFYP I IL GGY+A + N
Sbjct:  244 ISPETLKNILQNNMCESFYNSCRIIDCRFEYEYTGGHIINSVNIHS-RDELEYEFIHKVLHSDTSNNNTLPTL--------------LIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGGYKAVFDN 367
[Close]
BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Match: sp|A5D7P0|MPIP3_BOVIN (M-phase inducer phosphatase 3 OS=Bos taurus OX=9913 GN=CDC25C PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.987e-18
Identity = 47/114 (41.23%), Postives = 67/114 (58.77%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            IID R+P+E+ GGHI GA+NL +  +++ +F      K     DN + +V              ++FHCEFSS R P+M   LR  DR   L+ YP L+YP+++ILKGGYR F+
Sbjct:  331 IIDCRYPYEYLGGHIQGALNLHSQEELYNFFLK----KPIVPWDNQKRIV--------------IVFHCEFSSERGPRMCRSLREEDR--TLNQYPALYYPELYILKGGYRDFF 424
[Close]
BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Match: sp|P30307|MPIP3_HUMAN (M-phase inducer phosphatase 3 OS=Homo sapiens OX=9606 GN=CDC25C PE=1 SV=2)

HSP 1 Score: 88.1965 bits (217), Expect = 6.987e-18
Identity = 45/114 (39.47%), Postives = 69/114 (60.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            +ID R+P+E+ GGHI GA+NL++  ++F +F                 + + I+ L      + ++FHCEFSS R P+M   LR  DR  +L+ YP L+YP+++ILKGGYR F+
Sbjct:  327 VIDCRYPYEYLGGHIQGALNLYSQEELFNFF-----------------LKKPIVPLDT-QKRIIIVFHCEFSSERGPRMCRCLREEDR--SLNQYPALYYPELYILKGGYRDFF 420
[Close]
BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Match: sp|P30309|MPI1B_XENLA (M-phase inducer phosphatase 1-B OS=Xenopus laevis OX=8355 GN=cdc25-1-b PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 7.505e-18
Identity = 49/118 (41.53%), Postives = 64/118 (54.24%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNK 814
            IID R+P+E++GGHI GA+NL    +V  YF       T + K                   L +IFHCEFSS R PKM   LR  DR  N   YP L+YP++++LKGGY+ F+   K
Sbjct:  407 IIDCRYPYEYDGGHIKGALNLHRQEEVTDYFLKQPLTPTMAQK------------------RLIIIFHCEFSSERGPKMCRFLREEDRARNE--YPSLYYPELYLLKGGYKDFFPEYK 504
[Close]
BLAST of M-phase inducer phosphatase vs. TrEMBL
Match: A0A1I8HB98 (Rhodanese domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 6.239e-27
Identity = 62/157 (39.49%), Postives = 87/157 (55.41%), Query Frame = 2 
Query:  338 GKANKRISEPTDNII--TIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            G + +R + PT   +   I  +  D V ++V   ++    +Y IID R+P+EF+GGHI GAVN+FT  D+ + F  P             +                LIFHCEFSS RAPK+A  LR  DR AN+  YP LFYP++++L+GGY+AFY
Sbjct:   48 GNSEQRHALPTVKELDYGIRHVTSDTVSRLVNGEFSSTVPSYAIIDCRYPYEFSGGHIQGAVNVFTQEDLLRRFLEPASQAAAVPATKASV----------------LIFHCEFSSERAPKLARFLRQRDREANVCNYPDLFYPEVYVLQGGYKAFY 188
[Close]
BLAST of M-phase inducer phosphatase vs. TrEMBL
Match: R7UX06 (Rhodanese domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_140715 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 7.443e-27
Identity = 60/160 (37.50%), Postives = 86/160 (53.75%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHG 865
            ++ I  + V  ++   Y+    NY I+D R+P+E+ GGHI GA N++T  D+F  F   D+  +++   N + V+               IFHCEFSS R PKM   LR  DR  N D YP L YP+I+IL+GGY+AFY +         YK  + +DH 
Sbjct:   21 LQGISPETVSNLIRGEYSEVIDNYVIVDCRYPYEYEGGHIQGAQNIYTKSDIFDRFMKSDEFTSKAVDSNKKNVI---------------IFHCEFSSERGPKMCRYLRESDRKENADQYPRLTYPEIYILEGGYKAFYEHESSQCTPQTYKPMLHADHS 165
[Close]
BLAST of M-phase inducer phosphatase vs. TrEMBL
Match: R7TEC6 (Rhodanese domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_46992 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 7.534e-27
Identity = 60/160 (37.50%), Postives = 86/160 (53.75%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHG 865
            ++ I  + V  ++   Y+    NY I+D R+P+E+ GGHI GA N++T  D+F  F   D+  +++   N + V+               IFHCEFSS R PKM   LR  DR  N D YP L YP+I+IL+GGY+AFY +         YK  + +DH 
Sbjct:   22 LQAISPETVSNLIRGEYSEVIDNYVIVDCRYPYEYEGGHIEGAQNIYTKSDIFDRFMKSDEFTSKAVDSNKKNVI---------------IFHCEFSSERGPKMCRYLRESDRKENADQYPRLTYPEIYILEGGYKAFYEHESSQCTPQTYKPMLHADHS 166
[Close]
BLAST of M-phase inducer phosphatase vs. TrEMBL
Match: R7UUA1 (Rhodanese domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_127155 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 1.475e-26
Identity = 61/160 (38.12%), Postives = 87/160 (54.37%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHG 865
            ++ I  + V  ++   Y+ +  NY I+D R+P+E+ GGHI GA N++T  D+   F   D+L +++     +   +NII           IFHCEFSS R PKM   LR  DR  N D YP L YP+I+IL+GGY+AFY +         YK  +  DH 
Sbjct:   45 LQAISSETVSNLLRGEYSEEIDNYVIVDCRYPYEYQGGHIEGAENVYTKSDILDRFMKSDELTSKA----ADSKKKNII-----------IFHCEFSSERGPKMCRYLRETDRKENTDQYPKLTYPEIYILEGGYKAFYEHESSQCTPQAYKPMLHIDHS 189
[Close]
BLAST of M-phase inducer phosphatase vs. TrEMBL
Match: R7V7W7 (Rhodanese domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_89061 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 2.435e-26
Identity = 60/160 (37.50%), Postives = 86/160 (53.75%), Query Frame = 2 
Query:  386 IEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHG 865
            ++ I  + V  ++   Y+    NY I+D R+P+E+ GGHI GA N++T  D+   F   D+  +++   N     +N+I           IFHCEFSS R PKM   LR  DR  N D YP L YP+I+IL+GGY+AFY +         YK  + +DH 
Sbjct:   21 LQAISPETVSNLIRGEYSEVIDNYVIVDCRYPYEYEGGHIEGAQNIYTKSDILDRFMKSDEFTSKAVDSN----TKNVI-----------IFHCEFSSERGPKMCRYLRESDRKENADQYPRLTYPEIYILEGGYKAFYEHESSQCTPQTYKPMLHADHS 165
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Cavefish
Match: CDC25B (cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726])

HSP 1 Score: 87.0409 bits (214), Expect = 3.001e-18
Identity = 57/163 (34.97%), Postives = 84/163 (51.53%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYYI 943
            +ID R+P+EF GGHI GA+NL     +   FF    L    DK  L                  L+FHCEFSS R P+M   +R  DR  +L+ YP+L YP++++LKGGY+ F+  +K   +   Y+  V  D    +++    F+   +T+  + SKR  YI
Sbjct:  413 VIDCRYPYEFEGGHIKGALNLHLEEQIEDRFFSQPFLPQSPDKRVL------------------LVFHCEFSSERGPRMCRFVRERDR--DLNEYPNLHYPELYVLKGGYKDFFPLHKRECEPQDYRPMVHED----YKDDLRKFRLKSRTWAGERSKRDMYI 551
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Cavefish
Match: cdc25d (cell division cycle 25 homolog d [Source:ZFIN;Acc:ZDB-GENE-090313-74])

HSP 1 Score: 56.225 bits (134), Expect = 1.242e-8
Identity = 52/184 (28.26%), Postives = 84/184 (45.65%), Query Frame = 2 
Query:  362 EPTDNIITIEDIDVDRVKKIVENNYTIDGL----------NYCIIDSRFPFEFNGGHI--IGAVNLFTPLDVFQYFFGP-----DQLKTQSDKDNLELVVRNIINLQKFSSNLN------------------LIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMN 808
            +P  +++ +E +    +  +  +  T+ GL          ++ IID R+P+EF GGHI   GAVNL+T   + Q F             Q D  + E      +       + +                  ++FHCEFSS R P+  + LR +DR  N   YP L YP++++L+GGY+ FY +
Sbjct:   68 DPEHHVLPVERVGYQELHCV--SAQTVAGLITAQFSAVVEDFLIIDCRYPYEFKGGHIKLQGAVNLYTEHQIHQAFLQSFSNFQTSPGAQQDPRSPEAGAVGGVQGPGSGGSRSSAVSGEIKDGGSSCPRKLIVFHCEFSSERGPR-CQYLRELDRAVNTQNYPLLLYPELYLLQGGYKHFYTH 248
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Yeast
Match: MIH1 (Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25 [Source:SGD;Acc:S000004639])

HSP 1 Score: 92.8189 bits (229), Expect = 3.931e-21
Identity = 56/139 (40.29%), Postives = 73/139 (52.52%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYC-IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMN 808
            I  + +K I++NN      N C IID RF +E+ GGHII +VN+ +  D  +Y F    L + +  +N    +              LI HCEFSS R P +A  LR  DR  N D YP LFYP I IL GGY+A + N
Sbjct:  244 ISPETLKNILQNNMCESFYNSCRIIDCRFEYEYTGGHIINSVNIHS-RDELEYEFIHKVLHSDTSNNNTLPTL--------------LIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGGYKAVFDN 367
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Nematostella
Match: EDO39841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8Z1])

HSP 1 Score: 92.4337 bits (228), Expect = 2.254e-22
Identity = 51/136 (37.50%), Postives = 75/136 (55.15%), Query Frame = 2 
Query:  395 IDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFY 802
            I  + V K++  +Y  +   Y IID R+PFEF+GGH+ GA+N++T  ++ + F     + T   K+   +VV               IFHCEFSS R P M   LR  DR  +   YP LFYP++++L GGY+ F+
Sbjct:   36 ISPETVTKLINGDYKDEIDEYYIIDCRYPFEFDGGHVKGAINIYTKDEMLKQF-----IDTPKCKEGKRVVV---------------IFHCEFSSKRGPDMCRFLRNRDRDIHRPSYPSLFYPELYLLDGGYKNFF 151
[Close]
BLAST of M-phase inducer phosphatase vs. Ensembl Medaka
Match: ENSORLT00000022793.2 (cell division cycle 25B [Source:NCBI gene;Acc:101168663])

HSP 1 Score: 82.4185 bits (202), Expect = 9.120e-17
Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 2 
Query:  461 IIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ*SIKTF--KNSKRYYY 940
            +ID R+P+EF GGHI GA+N                L++Q +    E ++R  I        + ++FHCEFSS R P+M   +R  DR   L+ YP L YP+++ILKGGY+ F+ + +   +   Y+     D    F+E    F+   +T+  + SKR  Y
Sbjct:  429 VIDCRYPYEFEGGHIKGALNF--------------HLESQVE----EFLLRTPIVPSSPEKRVVVVFHCEFSSERGPRMCRFIRERDR--ALNDYPKLHYPELYILKGGYKDFFPHFQAQCEPQAYRPMHHED----FKEDLRRFRLKSRTWAGERSKRDMY 566
[Close]
BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Match: SMESG000025390.1 (SMESG000025390.1)

HSP 1 Score: 497.664 bits (1280), Expect = 7.946e-179
Identity = 271/272 (99.63%), Postives = 272/272 (100.00%), Query Frame = 2 
Query:   83 MEIDSIDFKMFXXXXXXXXXXMDVSYELVTTNFANEYDXXXXXXXXXXXXXXXXDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ 898
            MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNL+TPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ
Sbjct:    1 MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLYTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLLLYKMQVFSDHGIRFQETNNIFQ 272
[Close]
BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Match: SMESG000025390.1 (SMESG000025390.1)

HSP 1 Score: 440.654 bits (1132), Expect = 1.937e-155
Identity = 243/244 (99.59%), Postives = 244/244 (100.00%), Query Frame = 2 
Query:   83 MEIDSIDFKMFXXXXXXXXXXMDVSYELVTTNFANEYDXXXXXXXXXXXXXXXXDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNK 814
            MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNL+TPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNK
Sbjct:    1 MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLYTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNK 244
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BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Match: SMESG000025390.1 (SMESG000025390.1)

HSP 1 Score: 355.91 bits (912), Expect = 9.585e-124
Identity = 204/205 (99.51%), Postives = 205/205 (100.00%), Query Frame = 2 
Query:   83 MEIDSIDFKMFXXXXXXXXXXMDVSYELVTTNFANEYDXXXXXXXXXXXXXXXXDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKM 697
            MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNL+TPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKM
Sbjct:    1 MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTRSSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLYTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKM 205
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BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Match: SMESG000075488.1 (SMESG000075488.1)

HSP 1 Score: 135.191 bits (339), Expect = 3.283e-35
Identity = 65/157 (41.40%), Postives = 100/157 (63.69%), Query Frame = 2 
Query:  371 DNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPD------QLKTQSDKDNLELVVRNIINLQKFSSNLN---LIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNK 814
            +N I I ++  D V KI+EN++T D   Y IID R+P+E++GGH++GAVNL+TP  +  Y F         +   ++ +D++  ++  IIN++K +S+      IFHCEFSS R P+MA  +R +DR+ N  C  +LF+PK+ I+K GYR FY  +K
Sbjct:  266 ENDIKITEVSADFVAKIIENDFTSDSYAYHIIDCRYPYEYDGGHLLGAVNLYTPWQLLNYIFLAQNDLEYLKQPVENTEDSMVDLINTIINIKKPNSSWKTEAFIFHCEFSSVRGPEMARCMRNMDRYVNFSCQSNLFFPKVHIMKKGYREFYSKHK 422
[Close]
BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Match: SMESG000054042.1 (SMESG000054042.1)

HSP 1 Score: 95.9005 bits (237), Expect = 1.867e-21
Identity = 48/150 (32.00%), Postives = 85/150 (56.67%), Query Frame = 2 
Query:  356 ISEPTDNIITIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTPLDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSARAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYM 805
            + E + N + I +I    +  ++   Y+    +Y IID RFP+E++GGHI  ++N++T   + QYF    Q   + D  ++  +  +  + +        IF+CEFSS R PK+AE LR +D+ +NL+  P + +P +++L GGY  F++
Sbjct:  228 MRESSLNHLLIPEISNQTLSDLLVGRYSCYLSDYIIIDCRFPYEYDGGHISNSINVYTCRQMMQYFCQSTQPDMEQDLQHVLKLFESPNSSEDDFDTKAFIFYCEFSSFRGPKLAECLRGLDKLSNLESLPRVKFPHVYVLHGGYNEFFI 377
The following BLAST results are available for this feature:
BLAST of M-phase inducer phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDC25C6.243e-1939.47cell division cycle 25C [Source:HGNC Symbol;Acc:HG... [more]
CDC25C1.265e-1839.47cell division cycle 25C [Source:HGNC Symbol;Acc:HG... [more]
CDC25C1.440e-1839.47cell division cycle 25C [Source:HGNC Symbol;Acc:HG... [more]
CDC25C1.440e-1839.47cell division cycle 25C [Source:HGNC Symbol;Acc:HG... [more]
CDC25C1.455e-1839.47cell division cycle 25C [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdc-25.13.350e-1736.21M-phase inducer phosphatase cdc-25.1 [Source:UniP... [more]
cdc-25.13.350e-1736.21M-phase inducer phosphatase cdc-25.1 [Source:UniP... [more]
cdc-25.33.804e-1737.93M-phase inducer phosphatase cdc-25.3 [Source:UniP... [more]
cdc-25.23.097e-1436.21M-phase inducer phosphatase cdc-25.2 [Source:UniP... [more]
cdc-25.23.757e-1436.21M-phase inducer phosphatase cdc-25.2 [Source:UniP... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stg8.284e-2238.13gene:FBgn0003525 transcript:FBtr0085397[more]
stg8.284e-2238.13gene:FBgn0003525 transcript:FBtr0334867[more]
twe4.297e-1638.79gene:FBgn0002673 transcript:FBtr0331444[more]
twe4.297e-1638.79gene:FBgn0002673 transcript:FBtr0331445[more]
twe4.297e-1638.79gene:FBgn0002673 transcript:FBtr0331446[more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cdc25d1.055e-1934.51cell division cycle 25 homolog d [Source:ZFIN;Acc:... [more]
cdc25b1.342e-1834.57cell division cycle 25B [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adcy75.147e-2138.93adenylate cyclase 7 [Source:Xenbase;Acc:XB-GENE-10... [more]
ENSXETT00000036492.11.294e-2038.24M-phase inducer phosphatase 3-like [Source:NCBI ge... [more]
man2b11.779e-1835.19mannosidase, alpha, class 2B, member 1 [Source:Xen... [more]
man2b11.960e-1835.19mannosidase, alpha, class 2B, member 1 [Source:Xen... [more]
man2b12.185e-1835.19mannosidase, alpha, class 2B, member 1 [Source:Xen... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdc25c8.843e-1833.82cell division cycle 25C [Source:MGI Symbol;Acc:MGI... [more]
Cdc25b1.633e-1738.33cell division cycle 25B [Source:MGI Symbol;Acc:MGI... [more]
Cdc25b1.655e-1739.32cell division cycle 25B [Source:MGI Symbol;Acc:MGI... [more]
Cdc25a2.417e-1737.19cell division cycle 25A [Source:MGI Symbol;Acc:MGI... [more]
Cdc25a2.552e-1732.93cell division cycle 25A [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of M-phase inducer phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P20483|MPIP_DROME8.303e-2138.13M-phase inducer phosphatase OS=Drosophila melanoga... [more]
sp|P23748|MPIP_YEAST2.730e-1940.29M-phase inducer phosphatase OS=Saccharomyces cerev... [more]
sp|A5D7P0|MPIP3_BOVIN2.987e-1841.23M-phase inducer phosphatase 3 OS=Bos taurus OX=991... [more]
sp|P30307|MPIP3_HUMAN6.987e-1839.47M-phase inducer phosphatase 3 OS=Homo sapiens OX=9... [more]
sp|P30309|MPI1B_XENLA7.505e-1841.53M-phase inducer phosphatase 1-B OS=Xenopus laevis ... [more]
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BLAST of M-phase inducer phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HB986.239e-2739.49Rhodanese domain-containing protein OS=Macrostomum... [more]
R7UX067.443e-2737.50Rhodanese domain-containing protein (Fragment) OS=... [more]
R7TEC67.534e-2737.50Rhodanese domain-containing protein (Fragment) OS=... [more]
R7UUA11.475e-2638.13Rhodanese domain-containing protein (Fragment) OS=... [more]
R7V7W72.435e-2637.50Rhodanese domain-containing protein (Fragment) OS=... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CDC25B3.001e-1834.97cell division cycle 25B [Source:HGNC Symbol;Acc:HG... [more]
cdc25d1.242e-828.26cell division cycle 25 homolog d [Source:ZFIN;Acc:... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of M-phase inducer phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
MIH13.931e-2140.29Protein tyrosine phosphatase involved in cell cycl... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO398412.254e-2237.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of M-phase inducer phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSORLT00000022793.29.120e-1733.33cell division cycle 25B [Source:NCBI gene;Acc:1011... [more]
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BLAST of M-phase inducer phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000025390.17.946e-17999.63SMESG000025390.1[more]
SMESG000025390.11.937e-15599.59SMESG000025390.1[more]
SMESG000025390.19.585e-12499.51SMESG000025390.1[more]
SMESG000075488.13.283e-3541.40SMESG000075488.1[more]
SMESG000054042.11.867e-2132.00SMESG000054042.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033670 ID=SMED30033670|Name=M-phase inducer phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=1108bp
CCGATCTTATTGTTTTAGAATGTATTGTTTTTCTTAACATTTTAGGTTAA
TTGACTTGAAGTTGAACAGTTAATTATTCAAAATGGAAATAGATTCTATT
GATTTTAAAATGTTTTCATCATCAAGTGAAACAGAAAACTCTTCTATGGA
CGTATCTTACGAATTAGTTACTACCAATTTTGCAAATGAATATGATTCAA
AGTCACGAAATAGTAAATCTGAATCTACTCGATCAAGTGAATCCGATATT
AACAATAGTATATGCTTCAATAGTTCAATATTAGTGATGTTACAGTGTGA
AGAAAAAGGCAACAAAAATGAATTATCGAAAGGAAATGGAAAAGCCAACA
AAAGAATCAGTGAACCGACTGATAATATAATCACAATTGAAGATATCGAT
GTCGATCGAGTTAAAAAAATTGTCGAAAACAATTATACAATTGATGGTTT
AAATTATTGCATAATTGATTCTCGATTTCCGTTTGAATTCAACGGAGGTC
ACATAATTGGAGCAGTGAATTTATTTACTCCGCTAGATGTGTTTCAATAC
TTTTTCGGGCCAGATCAACTAAAAACCCAATCGGATAAAGATAATCTCGA
ACTTGTCGTCAGAAATATCATTAATTTGCAAAAGTTTTCATCTAATTTGA
ATTTGATTTTCCACTGTGAATTTTCCAGCGCAAGAGCTCCTAAAATGGCC
GAAGAACTTAGGTGCATCGACAGATTTGCTAATCTTGATTGTTATCCACA
CTTGTTCTATCCTAAAATCTTCATTCTTAAAGGCGGATACCGAGCGTTCT
ATATGAATAACAAGGTTGGGCATGATTTACTATTATATAAAATGCAGGTT
TTCAGTGATCATGGAATTAGATTTCAAGAAACAAATAACATATTTCAATA
AAGTATTAAAACATTTAAAAATTCAAAAAGGTATTATTACATTTAATATT
TATTTTTTGCCGTTAGATGTAGTGAATAGGTGGCACTCACATTACTGCGC
CTAGACTGTCTTTGGAAGTTTCACAACCTTTTTAAGTAAGATTTTGATTA
AACACTTATTAAATTTGTGTTATTTAACAATTTTATTAATAATAATTAAA
ACGTAAAG
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protein sequence of SMED30033670-orf-1

>SMED30033670-orf-1 ID=SMED30033670-orf-1|Name=SMED30033670-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=273bp
MEIDSIDFKMFSSSSETENSSMDVSYELVTTNFANEYDSKSRNSKSESTR
SSESDINNSICFNSSILVMLQCEEKGNKNELSKGNGKANKRISEPTDNII
TIEDIDVDRVKKIVENNYTIDGLNYCIIDSRFPFEFNGGHIIGAVNLFTP
LDVFQYFFGPDQLKTQSDKDNLELVVRNIINLQKFSSNLNLIFHCEFSSA
RAPKMAEELRCIDRFANLDCYPHLFYPKIFILKGGYRAFYMNNKVGHDLL
LYKMQVFSDHGIRFQETNNIFQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:1902751positive regulation of cell cycle G2/M phase transition
GO:0006470protein dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036873Rhodanese-like_dom_sf
IPR001763Rhodanese-like_dom
Vocabulary: molecular function
TermDefinition
GO:0004725protein tyrosine phosphatase activity
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001763Rhodanese-like domainSMARTSM00450rhod_4coord: 105..245
e-value: 2.7E-11
score: 53.5
IPR001763Rhodanese-like domainPFAMPF00581Rhodanesecoord: 121..241
e-value: 2.2E-11
score: 44.2
IPR001763Rhodanese-like domainPROSITEPS50206RHODANESE_3coord: 121..244
score: 10.865
IPR036873Rhodanese-like domain superfamilyGENE3DG3DSA:3.40.250.10coord: 72..257
e-value: 6.3E-35
score: 122.2
IPR036873Rhodanese-like domain superfamilySUPERFAMILYSSF52821Rhodanese/Cell cycle control phosphatasecoord: 101..242
NoneNo IPR availablePANTHERPTHR10828M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25coord: 12..243
NoneNo IPR availablePANTHERPTHR10828:SF17CDC25-LIKE PROTEIN PHOSPHATASE TWINE-RELATEDcoord: 12..243