axis inhibition protein A

Overview
Nameaxis inhibition protein A (ADW27177.1)
Smed IDSMED30033656
Length (bp)2092
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of axis inhibition protein A (SMED30033656) t-SNE clustered cells

Violin plots show distribution of expression levels for axis inhibition protein A (SMED30033656) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of axis inhibition protein A (SMED30033656) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for axis inhibition protein A (SMED30033656) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033656

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 20

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30033656h1SMcG0010668 ADW27177.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30033656h1SMcG0010668 ADW27177.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30033656h1SMcG0010668 ADW27177.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30033656h1SMcG0010668 ADW27177.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30033656h1SMcG0010668 ADW27177.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30033656h1SMcG0010668 SMED30033656smed_20140614PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30033656h1SMcG0010668 SMED30033656smed_20140614PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30033656h1SMcG0010668 SMED30033656smed_20140614PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30033656h1SMcG0010668 SMED30033656smed_20140614PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30033656h1SMcG0010668 SMED30033656smed_20140614PMID:21806978
Iglesias et al., 2011		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:18063757
Gurley et al., 2008		whole organism asexual adult colorimetric in situ hybridization evidence
cephalic gangliaSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:18063757
Gurley et al., 2008		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:18063757
Gurley et al., 2008		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30033656h1SMcG0010668 GU808528.1smed_ncbi_20240424PMID:18063757
Gurley et al., 2008		whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30033656h1SMcG0010668 dd_Smed_v4_4900_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of axis inhibition protein A vs. Ensembl Human
Match: AXIN1 (axin 1 [Source:HGNC Symbol;Acc:HGNC:903])

HSP 1 Score: 90.8929 bits (224), Expect = 3.090e-18
Identity = 45/83 (54.22%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  783 IVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 862

HSP 2 Score: 78.9518 bits (193), Expect = 1.605e-14
Identity = 41/126 (32.54%), Postives = 65/126 (51.59%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI   +           K+ +     KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   92 LLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSES 217
[Close]
BLAST of axis inhibition protein A vs. Ensembl Human
Match: AXIN1 (axin 1 [Source:HGNC Symbol;Acc:HGNC:903])

HSP 1 Score: 90.8929 bits (224), Expect = 3.345e-18
Identity = 45/83 (54.22%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  747 IVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 826

HSP 2 Score: 79.337 bits (194), Expect = 1.524e-14
Identity = 41/126 (32.54%), Postives = 65/126 (51.59%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI   +           K+ +     KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   92 LLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSES 217
[Close]
BLAST of axis inhibition protein A vs. Ensembl Human
Match: AXIN2 (axin 2 [Source:HGNC Symbol;Acc:HGNC:904])

HSP 1 Score: 83.5741 bits (205), Expect = 4.458e-17
Identity = 46/120 (38.33%), Postives = 69/120 (57.50%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNS 605
            LL D  G  +FR FLE E+    L+FWFAC GF+  + +  K  ++ K IY+ YI + S  +  L+P TK  I D I  KQ +D  +FD AQ EI+ V+ +  Y  F+ S+ +  Y+++ 
Sbjct:   85 LLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGI-KKQQIDSIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRSG 203
[Close]
BLAST of axis inhibition protein A vs. Ensembl Human
Match: AXIN2 (axin 2 [Source:HGNC Symbol;Acc:HGNC:904])

HSP 1 Score: 85.5001 bits (210), Expect = 1.643e-16
Identity = 49/132 (37.12%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G  +FR FLE E+    L+FWFAC GF+  + +  K  ++ K IY+ YI + S  +  L+P TK  I D I  KQ +D  +FD AQ EI+ V+ +  Y  F+ S+ +  Y+++
Sbjct:   72 DSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGI-KKQQIDSIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRS 202

HSP 2 Score: 81.6481 bits (200), Expect = 2.878e-15
Identity = 38/85 (44.71%), Postives = 58/85 (68.24%), Query Frame = 3 
Query: 1680 SVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            S ++V Y+FCG+ +PYR    +     TLG FK  L ++G YRY+FK+  DEF   GAV EE  ++E VLP++EG+++ KVE+++
Sbjct:  762 SELVVTYFFCGEEIPYRRM--LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWEDETVLPMYEGRILGKVERID 843
[Close]
BLAST of axis inhibition protein A vs. Ensembl Human
Match: AXIN2 (axin 2 [Source:HGNC Symbol;Acc:HGNC:904])

HSP 1 Score: 85.5001 bits (210), Expect = 1.731e-16
Identity = 49/132 (37.12%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G  +FR FLE E+    L+FWFAC GF+  + +  K  ++ K IY+ YI + S  +  L+P TK  I D I  KQ +D  +FD AQ EI+ V+ +  Y  F+ S+ +  Y+++
Sbjct:   72 DSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGI-KKQQIDSIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRS 202

HSP 2 Score: 81.6481 bits (200), Expect = 2.455e-15
Identity = 38/85 (44.71%), Postives = 58/85 (68.24%), Query Frame = 3 
Query: 1680 SVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            S ++V Y+FCG+ +PYR    +     TLG FK  L ++G YRY+FK+  DEF   GAV EE  ++E VLP++EG+++ KVE+++
Sbjct:  697 SELVVTYFFCGEEIPYRRM--LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWEDETVLPMYEGRILGKVERID 778
[Close]
BLAST of axis inhibition protein A vs. Ensembl Celegans
Match: rgs-4 (Regulator of G protein Signaling [Source:UniProtKB/TrEMBL;Acc:H2KMK7])

HSP 1 Score: 51.6026 bits (122), Expect = 4.633e-7
Identity = 30/121 (24.79%), Postives = 63/121 (52.07%), Query Frame = 3 
Query:  243 FKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFK----SADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQ--CLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFK 587
            F  ++ D  G   F  FL+SE +   + FW+A +  K    S  R K    ++ +Y  +I +ES  A+ +  +T+ +I+  +  K+     ++I++ AQ  +  ++ K+ + RF+ + ++K
Sbjct:   64 FDHVIYDVDGRAQFTKFLQSEYSEENILFWWAVEELKAVGVSEGRTKFESTVQEMYDTFIAAESPLAINIDHDTRTDIIALVEGKEPSTFPENIYERAQAHVYRLMEKDCFSRFVHTNAYK 184
[Close]
BLAST of axis inhibition protein A vs. Ensembl Celegans
Match: rgs-4 (Regulator of G protein Signaling [Source:UniProtKB/TrEMBL;Acc:H2KMK7])

HSP 1 Score: 50.447 bits (119), Expect = 5.981e-7
Identity = 30/121 (24.79%), Postives = 63/121 (52.07%), Query Frame = 3 
Query:  243 FKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFK----SADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQ--CLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFK 587
            F  ++ D  G   F  FL+SE +   + FW+A +  K    S  R K    ++ +Y  +I +ES  A+ +  +T+ +I+  +  K+     ++I++ AQ  +  ++ K+ + RF+ + ++K
Sbjct:   24 FDHVIYDVDGRAQFTKFLQSEYSEENILFWWAVEELKAVGVSEGRTKFESTVQEMYDTFIAAESPLAINIDHDTRTDIIALVEGKEPSTFPENIYERAQAHVYRLMEKDCFSRFVHTNAYK 144
[Close]
BLAST of axis inhibition protein A vs. Ensembl Celegans
Match: rgs-4 (Regulator of G protein Signaling [Source:UniProtKB/TrEMBL;Acc:H2KMK7])

HSP 1 Score: 50.447 bits (119), Expect = 5.981e-7
Identity = 30/121 (24.79%), Postives = 63/121 (52.07%), Query Frame = 3 
Query:  243 FKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFK----SADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQ--CLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFK 587
            F  ++ D  G   F  FL+SE +   + FW+A +  K    S  R K    ++ +Y  +I +ES  A+ +  +T+ +I+  +  K+     ++I++ AQ  +  ++ K+ + RF+ + ++K
Sbjct:   24 FDHVIYDVDGRAQFTKFLQSEYSEENILFWWAVEELKAVGVSEGRTKFESTVQEMYDTFIAAESPLAINIDHDTRTDIIALVEGKEPSTFPENIYERAQAHVYRLMEKDCFSRFVHTNAYK 144
[Close]
BLAST of axis inhibition protein A vs. Ensembl Fly
Match: Axn (gene:FBgn0026597 transcript:FBtr0085554)

HSP 1 Score: 70.4774 bits (171), Expect = 3.415e-12
Identity = 35/79 (44.30%), Postives = 50/79 (63.29%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVE 1925
            IV + FC +PVPYR ++P  +   TL QFK  LPRRG +R+FFK  C++ D    +QEE   + D+LPL+  K +  V+
Sbjct:  661 IVVFSFCEEPVPYRIKIPGTQP--TLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILPLFGDKAMGLVK 736

HSP 2 Score: 64.6994 bits (156), Expect = 1.834e-10
Identity = 48/164 (29.27%), Postives = 80/164 (48.78%), Query Frame = 3 
Query:  141 SLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLN----DSQGVEIFRGFLESERATH--YLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTS 611
            S P   +P  ++ VK  T     T++  +P  +++   LN    D  GVE+F+ ++E E   +  +L F+FAC+G K   D EK+ Q+I  IYR   +S+   +  L+   K     K + +  L   IFD  Q  +   +    Y  F+ SE + LY+Q  ++
Sbjct:   17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIK---AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
[Close]
BLAST of axis inhibition protein A vs. Ensembl Fly
Match: Axn (gene:FBgn0026597 transcript:FBtr0334703)

HSP 1 Score: 70.4774 bits (171), Expect = 3.415e-12
Identity = 35/79 (44.30%), Postives = 50/79 (63.29%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVE 1925
            IV + FC +PVPYR ++P  +   TL QFK  LPRRG +R+FFK  C++ D    +QEE   + D+LPL+  K +  V+
Sbjct:  661 IVVFSFCEEPVPYRIKIPGTQP--TLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILPLFGDKAMGLVK 736

HSP 2 Score: 64.6994 bits (156), Expect = 1.834e-10
Identity = 48/164 (29.27%), Postives = 80/164 (48.78%), Query Frame = 3 
Query:  141 SLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLN----DSQGVEIFRGFLESERATH--YLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTS 611
            S P   +P  ++ VK  T     T++  +P  +++   LN    D  GVE+F+ ++E E   +  +L F+FAC+G K   D EK+ Q+I  IYR   +S+   +  L+   K     K + +  L   IFD  Q  +   +    Y  F+ SE + LY+Q  ++
Sbjct:   17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIK---AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
[Close]
BLAST of axis inhibition protein A vs. Ensembl Fly
Match: Axn (gene:FBgn0026597 transcript:FBtr0334702)

HSP 1 Score: 70.4774 bits (171), Expect = 3.571e-12
Identity = 35/79 (44.30%), Postives = 50/79 (63.29%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVE 1925
            IV + FC +PVPYR ++P  +   TL QFK  LPRRG +R+FFK  C++ D    +QEE   + D+LPL+  K +  V+
Sbjct:  615 IVVFSFCEEPVPYRIKIPGTQP--TLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILPLFGDKAMGLVK 690

HSP 2 Score: 64.6994 bits (156), Expect = 2.310e-10
Identity = 48/164 (29.27%), Postives = 80/164 (48.78%), Query Frame = 3 
Query:  141 SLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLN----DSQGVEIFRGFLESERATH--YLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTS 611
            S P   +P  ++ VK  T     T++  +P  +++   LN    D  GVE+F+ ++E E   +  +L F+FAC+G K   D EK+ Q+I  IYR   +S+   +  L+   K     K + +  L   IFD  Q  +   +    Y  F+ SE + LY+Q  ++
Sbjct:   17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIK---AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
[Close]
BLAST of axis inhibition protein A vs. Ensembl Fly
Match: Axn (gene:FBgn0026597 transcript:FBtr0085553)

HSP 1 Score: 70.4774 bits (171), Expect = 3.614e-12
Identity = 35/79 (44.30%), Postives = 50/79 (63.29%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVE 1925
            IV + FC +PVPYR ++P  +   TL QFK  LPRRG +R+FFK  C++ D    +QEE   + D+LPL+  K +  V+
Sbjct:  667 IVVFSFCEEPVPYRIKIPGTQP--TLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILPLFGDKAMGLVK 742

HSP 2 Score: 65.0846 bits (157), Expect = 1.704e-10
Identity = 48/164 (29.27%), Postives = 80/164 (48.78%), Query Frame = 3 
Query:  141 SLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLN----DSQGVEIFRGFLESERATH--YLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTS 611
            S P   +P  ++ VK  T     T++  +P  +++   LN    D  GVE+F+ ++E E   +  +L F+FAC+G K   D EK+ Q+I  IYR   +S+   +  L+   K     K + +  L   IFD  Q  +   +    Y  F+ SE + LY+Q  ++
Sbjct:   17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIK---AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
[Close]
BLAST of axis inhibition protein A vs. Ensembl Fly
Match: Axn (gene:FBgn0026597 transcript:FBtr0085555)

HSP 1 Score: 70.4774 bits (171), Expect = 3.614e-12
Identity = 35/79 (44.30%), Postives = 50/79 (63.29%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVE 1925
            IV + FC +PVPYR ++P  +   TL QFK  LPRRG +R+FFK  C++ D    +QEE   + D+LPL+  K +  V+
Sbjct:  667 IVVFSFCEEPVPYRIKIPGTQP--TLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILPLFGDKAMGLVK 742

HSP 2 Score: 65.0846 bits (157), Expect = 1.704e-10
Identity = 48/164 (29.27%), Postives = 80/164 (48.78%), Query Frame = 3 
Query:  141 SLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLN----DSQGVEIFRGFLESERATH--YLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTS 611
            S P   +P  ++ VK  T     T++  +P  +++   LN    D  GVE+F+ ++E E   +  +L F+FAC+G K   D EK+ Q+I  IYR   +S+   +  L+   K     K + +  L   IFD  Q  +   +    Y  F+ SE + LY+Q  ++
Sbjct:   17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIK---AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
[Close]
BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Match: axin2 (axin 2 (conductin, axil) [Source:NCBI gene;Acc:58080])

HSP 1 Score: 91.6633 bits (226), Expect = 1.015e-19
Identity = 49/133 (36.84%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNS 605
            D+PL         LL D  G ++FR +LE E+    L+FWFAC GF+  D +  K +++ K IY+ YI + S  A  L+P TK  I D I  +Q +D ++FD AQMEI+  + +  Y  F+ S+ +  Y++  
Sbjct:   75 DSPLARWTKSLHFLLGDQDGAQLFRAYLEREKCVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQ-IDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRTG 206
[Close]
BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Match: axin2 (axin 2 (conductin, axil) [Source:NCBI gene;Acc:58080])

HSP 1 Score: 93.2041 bits (230), Expect = 4.229e-19
Identity = 49/132 (37.12%), Postives = 75/132 (56.82%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G ++FR +LE E+    L+FWFAC GF+  D +  K +++ K IY+ YI + S  A  L+P TK  I D I  +Q +D ++FD AQMEI+  + +  Y  F+ S+ +  Y++ 
Sbjct:   75 DSPLARWTKSLHFLLGDQDGAQLFRAYLEREKCVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQ-IDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRT 205

HSP 2 Score: 83.5741 bits (205), Expect = 4.415e-16
Identity = 42/96 (43.75%), Postives = 58/96 (60.42%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            K    C     S  +V Y+FCG+ +PYR  +       TLG FK  L ++G YRYFFKR  DEF+  GAV EE   +  VLP++EGK++ KV++M+
Sbjct:  720 KKMSGCHSSLGSETVVTYFFCGEEIPYRRMMKT--HSLTLGHFKEQLRKKGNYRYFFKRASDEFE-CGAVFEEVWDDCTVLPMYEGKILGKVDRMD 812
[Close]
BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Match: axin2 (axin 2 (conductin, axil) [Source:NCBI gene;Acc:58080])

HSP 1 Score: 93.2041 bits (230), Expect = 4.229e-19
Identity = 49/132 (37.12%), Postives = 75/132 (56.82%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G ++FR +LE E+    L+FWFAC GF+  D +  K +++ K IY+ YI + S  A  L+P TK  I D I  +Q +D ++FD AQMEI+  + +  Y  F+ S+ +  Y++ 
Sbjct:   75 DSPLARWTKSLHFLLGDQDGAQLFRAYLEREKCVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQ-IDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRT 205

HSP 2 Score: 83.5741 bits (205), Expect = 4.415e-16
Identity = 42/96 (43.75%), Postives = 58/96 (60.42%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            K    C     S  +V Y+FCG+ +PYR  +       TLG FK  L ++G YRYFFKR  DEF+  GAV EE   +  VLP++EGK++ KV++M+
Sbjct:  720 KKMSGCHSSLGSETVVTYFFCGEEIPYRRMMKT--HSLTLGHFKEQLRKKGNYRYFFKRASDEFE-CGAVFEEVWDDCTVLPMYEGKILGKVDRMD 812
[Close]
BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Match: axin1 (axin 1 [Source:NCBI gene;Acc:57931])

HSP 1 Score: 82.4185 bits (202), Expect = 8.820e-16
Identity = 42/85 (49.41%), Postives = 59/85 (69.41%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESG--FTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I V YYFCG+P+PYRT V     G   TLGQFK LL ++G Y+Y+FK+   EFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  756 ITVAYYFCGEPIPYRTSV----KGRIVTLGQFKELLTKKGSYKYYFKKVSYEFD-CGVVFEEVREDDAILPIFEEKIIGKVEKVD 835

HSP 2 Score: 79.337 bits (194), Expect = 9.351e-15
Identity = 50/141 (35.46%), Postives = 75/141 (53.19%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSAD----REKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKS-----------ESFKLYLQNSTSSDNSK 626
            LL+D  G+ +FR FL+ E     L+FWFAC GF+  +     EK+ +L K IY+ YI   +   +  ++P TK  I D +  K  +D ++FD AQ EI+ ++ +  Y  F+KS           ES KL+   S+ S N K
Sbjct:   96 LLDDQDGIHLFRTFLKQEECADMLDFWFACSGFRKQEANDGNEKMLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCV-MKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLFSDQSSVSGNGK 235
[Close]
BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Match: axin1 (axin 1 [Source:NCBI gene;Acc:57931])

HSP 1 Score: 82.4185 bits (202), Expect = 8.820e-16
Identity = 42/85 (49.41%), Postives = 59/85 (69.41%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESG--FTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I V YYFCG+P+PYRT V     G   TLGQFK LL ++G Y+Y+FK+   EFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  756 ITVAYYFCGEPIPYRTSV----KGRIVTLGQFKELLTKKGSYKYYFKKVSYEFD-CGVVFEEVREDDAILPIFEEKIIGKVEKVD 835

HSP 2 Score: 79.337 bits (194), Expect = 9.351e-15
Identity = 50/141 (35.46%), Postives = 75/141 (53.19%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSAD----REKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKS-----------ESFKLYLQNSTSSDNSK 626
            LL+D  G+ +FR FL+ E     L+FWFAC GF+  +     EK+ +L K IY+ YI   +   +  ++P TK  I D +  K  +D ++FD AQ EI+ ++ +  Y  F+KS           ES KL+   S+ S N K
Sbjct:   96 LLDDQDGIHLFRTFLKQEECADMLDFWFACSGFRKQEANDGNEKMLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCV-MKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLFSDQSSVSGNGK 235
[Close]
BLAST of axis inhibition protein A vs. Ensembl Xenopus
Match: pak3 (p21 protein (Cdc42/Rac)-activated kinase 3 [Source:Xenbase;Acc:XB-GENE-961764])

HSP 1 Score: 89.3521 bits (220), Expect = 1.010e-17
Identity = 43/83 (51.81%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  798 IVVAYYFCGEPIPYRTMV--KGRVVTLGQFKELLTKKGNYRYYFKKVSDEFD-CGVVFEEVREDDMILPIYEEKIIGKVEKID 877

HSP 2 Score: 78.9518 bits (193), Expect = 1.561e-14
Identity = 44/120 (36.67%), Postives = 68/120 (56.67%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADR-----EKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLY 593
            LL+D  G+ +FR FL+ E     L+FWFAC GF+  +      EK  +L K IY+ YI  S    +  ++P TK  I D +  +Q +D ++FD AQ EI+ ++    Y  F+KS+++  Y
Sbjct:   92 LLDDQDGINLFRTFLQQENCADLLDFWFACSGFRKLEPNDSKVEKRLKLAKAIYKKYILDSNGIVSRQIKPATKSFIKDCVLRQQ-IDPAMFDQAQTEIQSMMEDNTYPVFLKSDTYLEY 210
[Close]
BLAST of axis inhibition protein A vs. Ensembl Xenopus
Match: pak3 (p21 protein (Cdc42/Rac)-activated kinase 3 [Source:Xenbase;Acc:XB-GENE-961764])

HSP 1 Score: 88.9669 bits (219), Expect = 1.175e-17
Identity = 43/83 (51.81%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  762 IVVAYYFCGEPIPYRTMV--KGRVVTLGQFKELLTKKGNYRYYFKKVSDEFD-CGVVFEEVREDDMILPIYEEKIIGKVEKID 841

HSP 2 Score: 78.5666 bits (192), Expect = 1.856e-14
Identity = 44/120 (36.67%), Postives = 68/120 (56.67%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADR-----EKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLY 593
            LL+D  G+ +FR FL+ E     L+FWFAC GF+  +      EK  +L K IY+ YI  S    +  ++P TK  I D +  +Q +D ++FD AQ EI+ ++    Y  F+KS+++  Y
Sbjct:   92 LLDDQDGINLFRTFLQQENCADLLDFWFACSGFRKLEPNDSKVEKRLKLAKAIYKKYILDSNGIVSRQIKPATKSFIKDCVLRQQ-IDPAMFDQAQTEIQSMMEDNTYPVFLKSDTYLEY 210
[Close]
BLAST of axis inhibition protein A vs. Ensembl Xenopus
Match: ampd2 (adenosine monophosphate deaminase 2 [Source:Xenbase;Acc:XB-GENE-982645])

HSP 1 Score: 85.5001 bits (210), Expect = 1.761e-17
Identity = 50/148 (33.78%), Postives = 77/148 (52.03%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADR--EKVYQLIKVIYRAYIRSESKTAVP--LQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLEN 644
            D+PL         LL D +G ++FR FLE +R    L+FWFAC GF+  D    K  ++ K IY+ YI S     V   L+P TK  + D +  ++ LD S+FD AQ E++  +    Y  F+ S+ +  Y +N+    +++S  L  
Sbjct:   70 DSPLARWAKSLHSLLGDKEGADLFRRFLERQRCVDTLDFWFACNGFRQMDPGDAKTLRVAKAIYKRYIESGGGGTVAKQLKPPTKSFLRDCVKGQR-LDPSMFDQAQAEVQASMEDNAYRLFLSSDIYLEYGENAAYFSSAESAGLGG 216
[Close]
BLAST of axis inhibition protein A vs. Ensembl Xenopus
Match: ENSXETT00000012979.1 (axin 2 (conductin, axil) [Source:NCBI gene;Acc:100380149])

HSP 1 Score: 84.3445 bits (207), Expect = 3.121e-16
Identity = 43/129 (33.33%), Postives = 75/129 (58.14%), Query Frame = 3 
Query:  249 VLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSAD--REKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKS 629
            +LL+D  G  +FR +LE E     L FWFAC GF++ D    K  +  K IYR Y+++ S  +  L+P+T+  + + + ++Q L++++FD AQ EI+  + +E +  F++S+  K Y +    S   +S
Sbjct:   75 LLLDDQDGATLFRMYLEGEGLVDLLSFWFACNGFRAMDPLEPKTSKTAKAIYRWYVQNSSAVSCRLKPSTRTQVKECVKNQQ-LNKTVFDQAQQEIQRAMEQEAFTSFLQSDICKEYARGVEDSPTPES 202

HSP 2 Score: 77.411 bits (189), Expect = 3.798e-14
Identity = 38/94 (40.43%), Postives = 61/94 (64.89%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEK 1928
            KA   C+G+G +++   YYFCG+ +PY   +   E   TL +FK LL ++G Y+Y+FK+   EF+   AV +E ++ + VLPL+E K++ KVE+
Sbjct:  618 KASSDCQGQGLAIV---YYFCGERIPY--MIRTKEPSLTLQEFKELLSKKGSYKYYFKKESHEFE-CNAVFQEVSEEDAVLPLFEEKIICKVER 705
[Close]
BLAST of axis inhibition protein A vs. Ensembl Xenopus
Match: rdd2 (riddle 2 [Source:Xenbase;Acc:XB-GENE-6453154])

HSP 1 Score: 62.7734 bits (151), Expect = 3.988e-11
Identity = 35/110 (31.82%), Postives = 60/110 (54.55%), Query Frame = 3 
Query:  270 GVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQ 599
            G+  FR FL+SE +   LEFW AC+  K++  +++   +  IY  +I++ES   + +   T+ +I   I+         FD AQ  I  ++ K+ + RF+KSE +K  +Q
Sbjct:   24 GLSAFRAFLKSEFSDENLEFWLACEDLKTSTSDQISSKVYDIYCEFIKAESPREINIDHKTRDDIAQNITQTTI---HCFDDAQKLILCLMAKDSFPRFLKSEHYKELVQ 130
[Close]
BLAST of axis inhibition protein A vs. Ensembl Mouse
Match: Axin1 (axin 1 [Source:MGI Symbol;Acc:MGI:1096327])

HSP 1 Score: 92.8189 bits (229), Expect = 5.736e-19
Identity = 51/108 (47.22%), Postives = 67/108 (62.04%), Query Frame = 3 
Query: 1626 NAYQEKVKAKGTCKGKGDSV-----IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            N    K + K   K  G S      I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  728 NKLPSKQRTKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 832

HSP 2 Score: 80.8777 bits (198), Expect = 2.862e-15
Identity = 46/127 (36.22%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI  S    +   +P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   97 LLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCV-MKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSES 222
[Close]
BLAST of axis inhibition protein A vs. Ensembl Mouse
Match: Axin1 (axin 1 [Source:MGI Symbol;Acc:MGI:1096327])

HSP 1 Score: 92.8189 bits (229), Expect = 5.736e-19
Identity = 51/108 (47.22%), Postives = 67/108 (62.04%), Query Frame = 3 
Query: 1626 NAYQEKVKAKGTCKGKGDSV-----IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            N    K + K   K  G S      I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  728 NKLPSKQRTKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 832

HSP 2 Score: 80.8777 bits (198), Expect = 2.862e-15
Identity = 46/127 (36.22%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI  S    +   +P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   97 LLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCV-MKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSES 222
[Close]
BLAST of axis inhibition protein A vs. Ensembl Mouse
Match: Axin1 (axin 1 [Source:MGI Symbol;Acc:MGI:1096327])

HSP 1 Score: 92.8189 bits (229), Expect = 5.882e-19
Identity = 50/96 (52.08%), Postives = 65/96 (67.71%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            KA G      DS I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  777 KAGGGSAPPCDS-IVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 868

HSP 2 Score: 80.8777 bits (198), Expect = 2.767e-15
Identity = 46/127 (36.22%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI  S    +   +P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   97 LLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCV-MKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSES 222
[Close]
BLAST of axis inhibition protein A vs. Ensembl Mouse
Match: Axin2 (axin 2 [Source:MGI Symbol;Acc:MGI:1270862])

HSP 1 Score: 82.0333 bits (201), Expect = 1.185e-15
Identity = 48/132 (36.36%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G  +FR FLE E+    L+FWFAC GF+  + +  K  ++ K IY+ YI + S  +  L+P TK  I D I  KQ +   +FD AQ EI+ V+ +  Y  F+ S+ +  Y+++
Sbjct:   72 DSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGI-KKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRS 202

HSP 2 Score: 81.2629 bits (199), Expect = 2.620e-15
Identity = 38/85 (44.71%), Postives = 57/85 (67.06%), Query Frame = 3 
Query: 1680 SVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            S ++V Y+FCG+ +PYR    +     TLG FK  L ++G YRY+FK+  DEF   GAV EE   +E VLP++EG+++ KVE+++
Sbjct:  759 SELVVTYFFCGEEIPYRRM--LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWDDETVLPMYEGRILGKVERID 840
[Close]
BLAST of axis inhibition protein A vs. Ensembl Mouse
Match: Axin2 (axin 2 [Source:MGI Symbol;Acc:MGI:1270862])

HSP 1 Score: 81.6481 bits (200), Expect = 1.464e-15
Identity = 48/132 (36.36%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G  +FR FLE E+    L+FWFAC GF+  + +  K  ++ K IY+ YI + S  +  L+P TK  I D I  KQ +   +FD AQ EI+ V+ +  Y  F+ S+ +  Y+++
Sbjct:   72 DSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGI-KKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRS 202

HSP 2 Score: 81.2629 bits (199), Expect = 1.998e-15
Identity = 38/85 (44.71%), Postives = 57/85 (67.06%), Query Frame = 3 
Query: 1680 SVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            S ++V Y+FCG+ +PYR    +     TLG FK  L ++G YRY+FK+  DEF   GAV EE   +E VLP++EG+++ KVE+++
Sbjct:  694 SELVVTYFFCGEEIPYRRM--LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWDDETVLPMYEGRILGKVERID 775
[Close]
BLAST of axis inhibition protein A vs. UniProt/SwissProt
Match: sp|P57095|AXIN2_DANRE (Axin-2 OS=Danio rerio OX=7955 GN=axin2 PE=1 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 3.193e-18
Identity = 49/132 (37.12%), Postives = 75/132 (56.82%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G ++FR +LE E+    L+FWFAC GF+  D +  K +++ K IY+ YI + S  A  L+P TK  I D I  +Q +D ++FD AQMEI+  + +  Y  F+ S+ +  Y++ 
Sbjct:   75 DSPLARWTKSLHFLLGDQDGAQLFRAYLEREKCVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQ-IDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRT 205

HSP 2 Score: 83.5741 bits (205), Expect = 3.333e-15
Identity = 42/96 (43.75%), Postives = 58/96 (60.42%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            K    C     S  +V Y+FCG+ +PYR  +       TLG FK  L ++G YRYFFKR  DEF+  GAV EE   +  VLP++EGK++ KV++M+
Sbjct:  720 KKMSGCHSSLGSETVVTYFFCGEEIPYRRMMKT--HSLTLGHFKEQLRKKGNYRYFFKRASDEFE-CGAVFEEVWDDCTVLPMYEGKILGKVDRMD 812
[Close]
BLAST of axis inhibition protein A vs. UniProt/SwissProt
Match: sp|O35625|AXIN1_MOUSE (Axin-1 OS=Mus musculus OX=10090 GN=Axin1 PE=1 SV=3)

HSP 1 Score: 92.8189 bits (229), Expect = 4.026e-18
Identity = 50/96 (52.08%), Postives = 65/96 (67.71%), Query Frame = 3 
Query: 1647 KAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            KA G      DS I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  772 KAGGGSAPPCDS-IVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 863

HSP 2 Score: 81.2629 bits (199), Expect = 1.896e-14
Identity = 46/127 (36.22%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI  S    +   +P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   92 LLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCV-MKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSES 217
[Close]
BLAST of axis inhibition protein A vs. UniProt/SwissProt
Match: sp|O70239|AXIN1_RAT (Axin-1 OS=Rattus norvegicus OX=10116 GN=Axin1 PE=1 SV=3)

HSP 1 Score: 92.4337 bits (228), Expect = 5.312e-18
Identity = 50/108 (46.30%), Postives = 67/108 (62.04%), Query Frame = 3 
Query: 1626 NAYQEKVKAKGTCKGKGDSV-----IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            N    K + K   K  G S      I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E +LP++E K++ KVEK++
Sbjct:  723 NKLPSKQRTKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAILPVFEEKIIGKVEKVD 827

HSP 2 Score: 80.8777 bits (198), Expect = 1.878e-14
Identity = 46/127 (36.22%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYI-RSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI  S    +   +P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   92 LLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCV-MKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSES 217
[Close]
BLAST of axis inhibition protein A vs. UniProt/SwissProt
Match: sp|O15169|AXIN1_HUMAN (Axin-1 OS=Homo sapiens OX=9606 GN=AXIN1 PE=1 SV=2)

HSP 1 Score: 90.8929 bits (224), Expect = 1.484e-17
Identity = 45/83 (54.22%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  ++E VLP++E K++ KVEK++
Sbjct:  783 IVVAYYFCGEPIPYRTLV--RGRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLPVFEEKIIGKVEKVD 862

HSP 2 Score: 78.9518 bits (193), Expect = 7.709e-14
Identity = 41/126 (32.54%), Postives = 65/126 (51.59%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L + IYR YI   +           K+ +     KQ +D ++FD AQ EI+  + +  Y  F+KS+ +  Y +  + S
Sbjct:   92 LLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSES 217
[Close]
BLAST of axis inhibition protein A vs. UniProt/SwissProt
Match: sp|O42400|AXIN1_CHICK (Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 7.460e-17
Identity = 43/83 (51.81%), Postives = 60/83 (72.29%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            I+V YYFCG+P+PYRT V       TLGQFK LL ++G YRY+FK+  DEFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  762 IVVAYYFCGEPIPYRTLV--KGRVVTLGQFKELLTKKGNYRYYFKKVSDEFD-CGVVFEEVREDDTILPIFEEKIIGKVEKID 841

HSP 2 Score: 74.3294 bits (181), Expect = 2.068e-12
Identity = 44/127 (34.65%), Postives = 68/127 (53.54%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            LL+D  G+ +FR FL+ E     L+FWFAC GF+      ++ EK  +L K IY+ YI   +   +  ++P TK  I D +   Q +D  +FD AQ EI+ ++    Y  F+KS+ +  Y +    S
Sbjct:   92 LLDDQDGINLFRTFLKQEDCADLLDFWFACSGFRKLEPCVSNEEKRLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVMKLQ-IDPDMFDQAQTEIQCMIEDNTYPLFLKSDIYLEYTRTGGES 217
[Close]
BLAST of axis inhibition protein A vs. TrEMBL
Match: G3C7W8 (Axis inhibition protein A OS=Schmidtea mediterranea OX=79327 GN=axinA PE=2 SV=1)

HSP 1 Score: 1155.58 bits (2988), Expect = 0.000e+0
Identity = 582/603 (96.52%), Postives = 590/603 (97.84%), Query Frame = 3 
Query:  120 YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTKANKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVVNETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPXXXXXXXXXXXXXXXXXXXXXSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNGNAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEK 1928
            YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESER THYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESF+LYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTK NKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVV+ETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPRQYRHHHHHDHHHFRTRRRNRSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNG+ YQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTK +      + K + K++K
Sbjct:    6 YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERVTHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFELYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTKTNKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVVDETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPRQYRHHHHHDHHHFRTRRRNRSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNGDTYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKMKMFFLCGKEKSLRKLKK 608
[Close]
BLAST of axis inhibition protein A vs. TrEMBL
Match: G3C7W9 (Axis inhibition protein B OS=Schmidtea mediterranea OX=79327 GN=axinB PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 6.049e-35
Identity = 97/247 (39.27%), Postives = 142/247 (57.49%), Query Frame = 3 
Query:  234 VVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADR---EKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDN--SKSENLENQIQN----------NIFRDVDCSHVNYSVNNASNHVS----MKGKRERSIN--------SEIPTKANKSKQCASGL---NKDRRSIAEADPTSFVNQLNKRLEKV 884
            + +  +LL +S  V  FR +L+S  + H+L+FWFACQGFK+ DR    K++QL KVIYRAYIRSES  AVPL+ NTKK+IVDK+S ++C DQSIFDTAQ+EIRD+L  EF + F++S+    Y++  +   N  S S  ++ QI +          +I R    + +N   +  S  V+     KG  + S            I T  N +    +G    +KDRR+++E DP +F   L  +LE++
Sbjct:   37 IDNLSLLLQESDSVTNFRLYLDSINSGHFLDFWFACQGFKNFDRSDTHKLHQLTKVIYRAYIRSESPYAVPLKQNTKKSIVDKLSDRKCFDQSIFDTAQLEIRDILSGEFLMNFLQSD---FYIEPKSFERNLLSNSSRIQEQISDIPVSSCSSSGHIGRKSSSARINAIASRGSEGVNDGNCNKGSTDNSFGQLYTAQNTGTITTVFNNNLMGNNGSGTGSKDRRNLSEIDPQAFAKLLYTKLEEI 280

HSP 2 Score: 114.39 bits (285), Expect = 1.631e-22
Identity = 51/83 (61.45%), Postives = 64/83 (77.11%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            ++VGYY   DPVPYRTQ+P  +   TLGQFK L+ ++GP+RYFFKR CDEFD  G V EE  +++ +LPLWEGKVVAK+EK E
Sbjct:  698 LVVGYYIGNDPVPYRTQIPDSQY-ITLGQFKSLVAKKGPFRYFFKRYCDEFD-CGVVHEEIIRDDAILPLWEGKVVAKIEKAE 778
[Close]
BLAST of axis inhibition protein A vs. TrEMBL
Match: A0A267DWY9 (DIX domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013569g1 PE=4 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 1.777e-23
Identity = 52/83 (62.65%), Postives = 62/83 (74.70%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            + VGY+FCGD VP+R   P  E   +L QFK LLP+RG YRYFFK+  DEFD GGAV EE T + D+LPLWEGKVV KVE++E
Sbjct:   40 LTVGYFFCGDSVPFRHDWPQPE--ISLAQFKRLLPKRGAYRYFFKKRSDEFDTGGAVFEEVTADGDLLPLWEGKVVGKVERVE 120
[Close]
BLAST of axis inhibition protein A vs. TrEMBL
Match: A0A0X3PP83 (DIX domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR165548 PE=4 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 4.560e-23
Identity = 50/83 (60.24%), Postives = 65/83 (78.31%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            +IVGYY C DPVPYR+Q P  E   TLGQFK L+P++GP+R+FFK+  DEFD  G VQ+E + ++  LPLW+GKVVAKVE++E
Sbjct:   38 LIVGYYLCDDPVPYRSQWPDPE--ITLGQFKHLVPKKGPFRFFFKKASDEFD-SGVVQQEISNDDATLPLWDGKVVAKVERIE 117
[Close]
BLAST of axis inhibition protein A vs. TrEMBL
Match: A0A158QGK2 (RGS domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS227 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 2.262e-22
Identity = 57/149 (38.26%), Postives = 87/149 (58.39%), Query Frame = 3 
Query:  234 VVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS----ADREKVYQLIKVIYRAYIRSESKTA------------------VPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
               F  LL+D +GV +F+ +L SE   + L+FWFA QGF+S    +DR+K+ QLIKVIY+ YIR  + T+                  V L+P T++ I D++S K  LDQ++FD AQ EI  +L    Y  F+KS++F +++Q  + +
Sbjct:   81 AASFDALLSDGEGVALFKSYLVSEGCGNLLDFWFAVQGFRSKVDPSDRKKILQLIKVIYQTYIRGSTSTSTVPPGSSSNARSRRTHTPVRLRPETRRAIADRLSHKSSLDQTVFDEAQTEIGHLLRTTAYQAFLKSDAFIMHIQEGSKA 229
[Close]
BLAST of axis inhibition protein A vs. Ensembl Cavefish
Match: axin2 (axin-2-like [Source:NCBI gene;Acc:103042974])

HSP 1 Score: 91.2781 bits (225), Expect = 1.407e-18
Identity = 48/132 (36.36%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G ++FR FLE E+    L+FWFAC GF+  D +  K  ++ K IY+ Y+ S    A  L+P TK  I D +  +Q +D S+FD AQ EI+  + +  Y  F+ S+ +  Y+++
Sbjct:   79 DSPLARWNKSLHSLLGDQDGAQLFRAFLEREKCVDALDFWFACNGFRQMDLKDGKTLRVAKAIYKRYVESSGVVAKQLKPATKTFIKDSVKRQQ-IDSSMFDQAQTEIQTTMEENAYQMFLTSDIYLEYVRS 209

HSP 2 Score: 78.9518 bits (193), Expect = 8.883e-15
Identity = 42/100 (42.00%), Postives = 61/100 (61.00%), Query Frame = 3 
Query: 1635 QEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            +E  K  G+    G S  +V Y+FCG+ +PYR  +       TL  FK  L ++G YRY+FK+  DEF+  GAV EE   +  VLP++EGK++ KVE+M+
Sbjct:  743 KEPKKTPGSHAAAG-SETVVTYFFCGEEIPYRRTMKT--HSLTLAHFKEQLRKKGNYRYYFKKASDEFE-CGAVFEEVWDDGSVLPMYEGKILGKVERMD 838
[Close]
BLAST of axis inhibition protein A vs. Ensembl Cavefish
Match: axin1 (axin 1 [Source:NCBI gene;Acc:103045152])

HSP 1 Score: 89.7373 bits (221), Expect = 4.015e-18
Identity = 50/102 (49.02%), Postives = 69/102 (67.65%), Query Frame = 3 
Query: 1635 QEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESG--FTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            Q K + KG  K   ++ IIV YYFCG+P+PYRT V     G   TLGQFK LL ++G YRY+FK+  DEFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  736 QTKQRHKGMKKQPCEN-IIVAYYFCGEPIPYRTSV----KGRIVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDDAILPIFEEKIIGKVEKID 831

HSP 2 Score: 79.337 bits (194), Expect = 7.766e-15
Identity = 51/142 (35.92%), Postives = 74/142 (52.11%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKS-----------ESFKLYLQNSTSSDNSK 626
            LL+D  G+ +FR FL+ E     L+FWFAC GF+       + EK  +L K IY+ YI   +   +  ++P TK  I D +  K  +D ++FD AQ EI+ ++ +  Y  F+KS           ES KLY   S+ S N K
Sbjct:   98 LLDDQDGIHLFRTFLKQEDCADMLDFWFACSGFRKLETSDGNEEKKLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCV-MKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLYSDQSSVSGNGK 238
[Close]
BLAST of axis inhibition protein A vs. Ensembl Cavefish
Match: axin1 (axin 1 [Source:NCBI gene;Acc:103045152])

HSP 1 Score: 89.3521 bits (220), Expect = 5.508e-18
Identity = 45/85 (52.94%), Postives = 61/85 (71.76%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESG--FTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            IIV YYFCG+P+PYRT V     G   TLGQFK LL ++G YRY+FK+  DEFD  G V EE  +++ +LP++E K++ KVEK++
Sbjct:  787 IIVAYYFCGEPIPYRTSV----KGRIVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDDAILPIFEEKIIGKVEKID 866

HSP 2 Score: 78.9518 bits (193), Expect = 8.905e-15
Identity = 51/142 (35.92%), Postives = 74/142 (52.11%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-----ADREKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKS-----------ESFKLYLQNSTSSDNSK 626
            LL+D  G+ +FR FL+ E     L+FWFAC GF+       + EK  +L K IY+ YI   +   +  ++P TK  I D +  K  +D ++FD AQ EI+ ++ +  Y  F+KS           ES KLY   S+ S N K
Sbjct:   98 LLDDQDGIHLFRTFLKQEDCADMLDFWFACSGFRKLETSDGNEEKKLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCV-MKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLYSDQSSVSGNGK 238
[Close]
BLAST of axis inhibition protein A vs. Ensembl Cavefish
Match: ENSAMXT00000043306.1 (axin 2 [Source:NCBI gene;Acc:103044632])

HSP 1 Score: 87.0409 bits (214), Expect = 2.684e-17
Identity = 45/132 (34.09%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL        +LL D  G  +FR FLE E+    L+FWFAC GF+  D +  K  ++ + IY+ Y+ +    A  ++P T+  I D I  KQ +D ++FD AQ EI+  + ++ Y  F+ S+ +  Y+ +
Sbjct:   70 DSPLARWTKSLHLLLGDQDGAHLFRTFLEREKGEDALDFWFACNGFRQMDLKDAKTQRVARAIYKRYVEASGVVAEQMKPATRSYIRDSI-KKQRVDSAMFDQAQTEIQAAMEEKAYQMFLTSDIYLDYVHS 200

HSP 2 Score: 81.6481 bits (200), Expect = 1.350e-15
Identity = 40/100 (40.00%), Postives = 63/100 (63.00%), Query Frame = 3 
Query: 1635 QEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            +++  + G       S ++V Y+FCG+ +PYR  +       TLG FK  L ++G YRY+FK+  DEF+  GAV EE  ++  VLP++EGK++ KVE+M+
Sbjct:  724 EQRRPSTGHSSAPSGSELVVTYFFCGEEIPYRRLMKT--HSLTLGHFKEQLRKKGNYRYYFKKASDEFE-CGAVFEEIWEDGTVLPMYEGKILGKVERMD 820
[Close]
BLAST of axis inhibition protein A vs. Ensembl Cavefish
Match: ENSAMXT00000049310.1 (axin 2 [Source:NCBI gene;Acc:103044632])

HSP 1 Score: 87.0409 bits (214), Expect = 2.797e-17
Identity = 45/132 (34.09%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL        +LL D  G  +FR FLE E+    L+FWFAC GF+  D +  K  ++ + IY+ Y+ +    A  ++P T+  I D I  KQ +D ++FD AQ EI+  + ++ Y  F+ S+ +  Y+ +
Sbjct:   70 DSPLARWTKSLHLLLGDQDGAHLFRTFLEREKGEDALDFWFACNGFRQMDLKDAKTQRVARAIYKRYVEASGVVAEQMKPATRSYIRDSI-KKQRVDSAMFDQAQTEIQAAMEEKAYQMFLTSDIYLDYVHS 200

HSP 2 Score: 83.1889 bits (204), Expect = 4.932e-16
Identity = 41/103 (39.81%), Postives = 65/103 (63.11%), Query Frame = 3 
Query: 1626 NAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            +A +++  + G       S ++V Y+FCG+ +PYR  +       TLG FK  L ++G YRY+FK+  DEF+  GAV EE  ++  VLP++EGK++ KVE+M+
Sbjct:  676 SASKQRRPSTGHSSAPSGSELVVTYFFCGEEIPYRRLMKT--HSLTLGHFKEQLRKKGNYRYYFKKASDEFE-CGAVFEEIWEDGTVLPMYEGKILGKVERMD 775
[Close]
BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008444.1 (pep scaffold:Pmarinus_7.0:GL479496:14395:17295:-1 gene:ENSPMAG00000007646.1 transcript:ENSPMAT00000008444.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.5741 bits (205), Expect = 7.420e-20
Identity = 41/79 (51.90%), Postives = 59/79 (74.68%), Query Frame = 3 
Query: 1698 YYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            YYFCG+P+PYR++V  G+S  TL  FK LL ++G YR++FK+  +EF+  G V EE   ++ +LPL++GKVV KVEK+E
Sbjct:   14 YYFCGEPIPYRSRVR-GDS-LTLAHFKELLTKKGNYRFYFKKASEEFE-CGVVFEEVRDDKALLPLYQGKVVGKVEKVE 89
[Close]
BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009992.1 (pep scaffold:Pmarinus_7.0:GL486030:972:8629:-1 gene:ENSPMAG00000009042.1 transcript:ENSPMAT00000009992.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 7.718e-18
Identity = 47/143 (32.87%), Postives = 79/143 (55.24%), Query Frame = 3 
Query:  189 PTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            PT  YV+  ++          LL+D  G  +FR FLE E     L+FWFAC GF++A R K+ +  ++IY+ Y+   +   A  L+  T+  + D + ++   D ++FD AQ+EI+  + +  Y  F+KSE   LYL+ + ++
Sbjct:   86 PTPPYVRWGES-------LHSLLDDRDGTHLFRTFLEHEELPDMLDFWFACNGFRNA-RHKMGKAARLIYKRYVSDTAGVVAAHLKAATRAYVRDCVLARGVADPTVFDQAQLEIQQQMEENSYPAFLKSE---LYLEYARAA 217
[Close]
BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007682.1 (pep scaffold:Pmarinus_7.0:GL479837:661:11661:1 gene:ENSPMAG00000006940.1 transcript:ENSPMAT00000007682.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.0333 bits (201), Expect = 1.743e-17
Identity = 41/86 (47.67%), Postives = 59/86 (68.60%), Query Frame = 3 
Query: 1677 DSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            DSV++V YYFCG+ +PYRT V       TLG FK LL ++G YRY+FK+  ++FD  G V EE   ++ +LP++E K+  KVE++E
Sbjct:  201 DSVVVV-YYFCGETIPYRTSV--RGHVLTLGHFKELLTKKGTYRYYFKKASEDFD-CGVVYEEVQDDDAILPIYEEKINGKVERIE 282
[Close]
BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005690.1 (pep scaffold:Pmarinus_7.0:GL485422:2197:11231:-1 gene:ENSPMAG00000005159.1 transcript:ENSPMAT00000005690.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.5741 bits (205), Expect = 1.830e-17
Identity = 44/143 (30.77%), Postives = 76/143 (53.15%), Query Frame = 3 
Query:  189 PTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAV-PLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            PT  YV+  ++          LL D  G  +FR FLE E     L+FWFAC GF+  D +K  +L K IY+ +I+  +   +  +   T+  + + I+SK+ +D ++FD AQ E++  + +  Y  F++S+ +  Y ++   S
Sbjct:   79 PTPPYVRWAES-------LPALLEDQDGTSLFRAFLEQEDCVDLLDFWFACSGFRKTDGDKRAKLAKAIYKKFIKDNAGIVLRQIGSITRTGVKECIASKR-IDSTMFDRAQEEVQTAMEENAYPAFLRSDVYLAYARSGGES 213
[Close]
BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009994.1 (pep scaffold:Pmarinus_7.0:GL486030:972:8338:-1 gene:ENSPMAG00000009042.1 transcript:ENSPMAT00000009994.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.2554 bits (186), Expect = 3.354e-15
Identity = 46/145 (31.72%), Postives = 77/145 (53.10%), Query Frame = 3 
Query:  189 PTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS--ADREKVYQLIKVIYRAYIRSESK-TAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSS 614
            PT  YV+  ++          LL+D  G  +FR FLE E     L+FWFAC GF++  A R+      ++IY+ Y+   +   A  L+  T+  + D + ++   D ++FD AQ+EI+  + +  Y  F+KSE   LYL+ + ++
Sbjct:   81 PTPPYVRWGES-------LHSLLDDRDGTHLFRTFLEHEELPDMLDFWFACNGFRNLLATRKAA----RLIYKRYVSDTAGVVAAHLKAATRAYVRDCVLARGVADPTVFDQAQLEIQQQMEENSYPAFLKSE---LYLEYARAA 211
[Close]
BLAST of axis inhibition protein A vs. Ensembl Nematostella
Match: EDO44861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUI9])

HSP 1 Score: 68.9366 bits (167), Expect = 4.238e-12
Identity = 37/90 (41.11%), Postives = 58/90 (64.44%), Query Frame = 3 
Query: 1665 KGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            K K ++  I+ Y+  G+P+ YRT +P      TLGQFK L+ R+G +RYFFK   ++ +    V EE  +++ +LP +EGK+V KVEK++
Sbjct:  745 KEKHNATTII-YWLWGEPIAYRTSLP--GKHITLGQFKTLIMRKGEFRYFFKTKTEDRE-CEVVYEEVKEDKMMLPTFEGKIVGKVEKVD 830
[Close]
BLAST of axis inhibition protein A vs. Ensembl Nematostella
Match: EDO32804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU35])

HSP 1 Score: 62.003 bits (149), Expect = 3.078e-11
Identity = 38/123 (30.89%), Postives = 63/123 (51.22%), Query Frame = 3 
Query:  240 DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNS 605
            DF  LL+   GV  F+ FL S+     L FW A + ++   DRE    + ++IY  Y+ + S T + L    +  +   +S     DQ+ FD AQ  I  ++  + + RFIKS+ +K  +++S
Sbjct:   45 DFHALLSSKYGVNQFQEFLRSQYGEENLCFWLAVEDYRRLEDRESRRDMARMIYEDYVSTLSPTEISLDAKIRATVDKSMSDP---DQNTFDPAQDHIYTLMYHDCFPRFIKSKHYKNLIKSS 164
[Close]
BLAST of axis inhibition protein A vs. Ensembl Nematostella
Match: EDO37370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFZ6])

HSP 1 Score: 56.9954 bits (136), Expect = 1.259e-9
Identity = 37/116 (31.90%), Postives = 59/116 (50.86%), Query Frame = 3 
Query:  243 FKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFK-SADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFK 587
            F+ LL+   G+ +F  FL+SE +   L FW A +  K   +   V  L + IY  Y+ +ES   V +   T++ I D+IS      +  F  AQ  +  V+ ++ Y RF+ S +FK
Sbjct:   37 FERLLSSKNGIRVFHEFLKSEYSEENLLFWLAVERLKKETEPASVKNLAQTIYNDYVSTESPKEVSIDHKTRQVIDDEISQP---TKETFSKAQQHVYYVMYQDCYPRFLSSSTFK 149
[Close]
BLAST of axis inhibition protein A vs. Ensembl Nematostella
Match: EDO37929 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEC9])

HSP 1 Score: 52.373 bits (124), Expect = 3.086e-7
Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 3 
Query: 1755 GFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEK 1928
              TL  FK +  R GPYR+ FK    EF   G V+EE  +++D++P WEGK+VA VE+
Sbjct:  293 NITLRDFKHMFDRPGPYRFHFKALDPEF---GTVKEEVIEDDDIIPGWEGKIVAWVEE 347
[Close]
BLAST of axis inhibition protein A vs. Ensembl Nematostella
Match: EDO34351 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPN2])

HSP 1 Score: 51.2174 bits (121), Expect = 7.818e-7
Identity = 33/116 (28.45%), Postives = 57/116 (49.14%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQ 599
            LL D  G + F  FLE E +   L FW AC+  K+   ++V +  + IY  Y+   S + + +   T + +   +       + +FD AQ  I  ++  + Y RF++SE +K  L+
Sbjct:  280 LLKDPLGRKYFTRFLEKEFSAENLAFWLACERLKATPIKQVPEKAQEIYTEYLSEHSTSPINVDCKTHEEVEMNLEKP---GRYMFDAAQDHIFQLMKSDSYSRFLRSELYKELLK 392
[Close]
BLAST of axis inhibition protein A vs. Ensembl Medaka
Match: axin2 (axin-2 [Source:NCBI gene;Acc:101159441])

HSP 1 Score: 87.4261 bits (215), Expect = 2.435e-17
Identity = 49/132 (37.12%), Postives = 73/132 (55.30%), Query Frame = 3 
Query:  222 DNPL---VVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PL         LL D  G  +FR FLE E+    L+FWFAC GF+  D +  K  ++ K IY+ YI ++S  A  L+P TK  I D +  KQ +D ++FD AQ EI+  + +  Y  F+ S+ +  Y++ 
Sbjct:   74 DSPLSRWTKSLHTLLGDQDGALLFRTFLEREKCVDTLDFWFACNGFRQMDLKDTKTQRVAKAIYKRYIENDSIVAKLLKPATKTFIRDTV-KKQHIDSAMFDQAQTEIQTNMEENAYQMFLTSDIYLDYVRT 204

HSP 2 Score: 83.1889 bits (204), Expect = 4.024e-16
Identity = 39/82 (47.56%), Postives = 55/82 (67.07%), Query Frame = 3 
Query: 1689 IVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            +V Y+FCG+ +PYR    +     TLG FK  L +RG YRY+FK+  DEF+  GAV EE + +  +LP +EGK++ KVE+ME
Sbjct:  756 VVTYFFCGEEIPYRRT--MKSHSLTLGHFKEQLRKRGSYRYYFKKASDEFE-CGAVFEEVSDDSSLLPTYEGKILGKVERME 834
[Close]
BLAST of axis inhibition protein A vs. Ensembl Medaka
Match: ENSORLT00000012346.2 (axin-1 [Source:NCBI gene;Acc:101155494])

HSP 1 Score: 86.6557 bits (213), Expect = 3.819e-17
Identity = 42/83 (50.60%), Postives = 59/83 (71.08%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            + V YYFCG+P+PYRT V       TLGQFK LL ++G Y+++FK+  DEFD  G V EE   ++D+LP++E K+V KVEK++
Sbjct:  761 MTVAYYFCGEPIPYRTSV--KGRVVTLGQFKELLTKKGHYKFYFKKVSDEFD-CGVVFEEIRNDDDILPIFEEKIVGKVEKID 840

HSP 2 Score: 81.2629 bits (199), Expect = 1.669e-15
Identity = 45/132 (34.09%), Postives = 69/132 (52.27%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQ 647
            LL+D  G ++F+ FL  E     L+FWFAC GF+ + +EK  +L K IY+ YI   S           K+ +     KQ  D ++FD AQ EI+ ++ +  Y  F+KS+   LYL+ + +   S   N  +Q
Sbjct:  108 LLDDQDGTQLFKNFLCQEGCADLLDFWFACSGFRQSSQEKRAKLAKAIYKKYIVDGSGIVSRQIKAATKSFIRDCVGKQHPDPAMFDQAQTEIQAMIEENTYPLFLKSD---LYLEYTRTGGESPKPNPSDQ 236
[Close]
BLAST of axis inhibition protein A vs. Ensembl Medaka
Match: ENSORLT00000029383.1 (axin-1 [Source:NCBI gene;Acc:101155494])

HSP 1 Score: 86.6557 bits (213), Expect = 4.217e-17
Identity = 43/85 (50.59%), Postives = 60/85 (70.59%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESG--FTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            + V YYFCG+P+PYRT V     G   TLGQFK LL ++G Y+++FK+  DEFD  G V EE   ++D+LP++E K+V KVEK++
Sbjct:  799 MTVAYYFCGEPIPYRTSV----KGRVVTLGQFKELLTKKGHYKFYFKKVSDEFD-CGVVFEEIRNDDDILPIFEEKIVGKVEKID 878

HSP 2 Score: 81.6481 bits (200), Expect = 1.520e-15
Identity = 45/132 (34.09%), Postives = 69/132 (52.27%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQ 647
            LL+D  G ++F+ FL  E     L+FWFAC GF+ + +EK  +L K IY+ YI   S           K+ +     KQ  D ++FD AQ EI+ ++ +  Y  F+KS+   LYL+ + +   S   N  +Q
Sbjct:  117 LLDDQDGTQLFKNFLCQEGCADLLDFWFACSGFRQSSQEKRAKLAKAIYKKYIVDGSGIVSRQIKAATKSFIRDCVGKQHPDPAMFDQAQTEIQAMIEENTYPLFLKSD---LYLEYTRTGGESPKPNPSDQ 245
[Close]
BLAST of axis inhibition protein A vs. Ensembl Medaka
Match: AXIN2 (axin 2 [Source:NCBI gene;Acc:101156143])

HSP 1 Score: 85.1149 bits (209), Expect = 9.814e-17
Identity = 49/132 (37.12%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PLV        LL D  G  +F+ FLE E     L+FWFAC GF+  D +  K  ++ KVI++ YI +    A  L+P TK  I D I  KQ +D ++FD AQ EI+  + +  Y  F+ S+ +  Y ++
Sbjct:   74 DSPLVRWAKSLHFLLGDQDGAHLFKTFLERENCVDTLDFWFACNGFRQMDLKDTKTLRVAKVIFKRYIDNNGIVAKQLKPATKTFIRDSI-KKQQIDSAMFDQAQTEIQSYMEENAYQMFLTSDIYLDYARS 204

HSP 2 Score: 83.5741 bits (205), Expect = 3.069e-16
Identity = 39/83 (46.99%), Postives = 58/83 (69.88%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            ++V Y+FCG+ +PYR+ +       TLG FK  L ++G YRY+FK+  DEF+  GAV EE  ++  VLP++EGKV+ KVE+M+
Sbjct:  712 LVVTYFFCGEEIPYRSMMKT--HCLTLGHFKEQLSKKGNYRYYFKKASDEFE-CGAVFEEVWEDAAVLPMYEGKVLGKVERMD 791
[Close]
BLAST of axis inhibition protein A vs. Ensembl Medaka
Match: AXIN2 (axin 2 [Source:NCBI gene;Acc:101156143])

HSP 1 Score: 85.1149 bits (209), Expect = 9.814e-17
Identity = 49/132 (37.12%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:  222 DNPLVV---DFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADRE--KVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            D+PLV        LL D  G  +F+ FLE E     L+FWFAC GF+  D +  K  ++ KVI++ YI +    A  L+P TK  I D I  KQ +D ++FD AQ EI+  + +  Y  F+ S+ +  Y ++
Sbjct:   74 DSPLVRWAKSLHFLLGDQDGAHLFKTFLERENCVDTLDFWFACNGFRQMDLKDTKTLRVAKVIFKRYIDNNGIVAKQLKPATKTFIRDSI-KKQQIDSAMFDQAQTEIQSYMEENAYQMFLTSDIYLDYARS 204

HSP 2 Score: 83.5741 bits (205), Expect = 3.069e-16
Identity = 39/83 (46.99%), Postives = 58/83 (69.88%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            ++V Y+FCG+ +PYR+ +       TLG FK  L ++G YRY+FK+  DEF+  GAV EE  ++  VLP++EGKV+ KVE+M+
Sbjct:  712 LVVTYFFCGEEIPYRSMMKT--HCLTLGHFKEQLSKKGNYRYYFKKASDEFE-CGAVFEEVWEDAAVLPMYEGKVLGKVERMD 791
[Close]
BLAST of axis inhibition protein A vs. Planmine SMEST
Match: SMESG000039725.1 (SMESG000039725.1)

HSP 1 Score: 1209.9 bits (3129), Expect = 0.000e+0
Identity = 606/606 (100.00%), Postives = 606/606 (100.00%), Query Frame = 3 
Query:  120 YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTKANKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVVNETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPXXXXXXXXXXXXXXXXXXXXXSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNGNAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKMEP 1937
            YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTKANKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVVNETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPRQYRHHHHHDHHHFRTRRRNRSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNGNAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKMEP
Sbjct:    6 YQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVNNASNHVSMKGKRERSINSEIPTKANKSKQCASGLNKDRRSIAEADPTSFVNQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCSFLMDRDLNKNDLVVNETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYSQQIYNPSPYINPPWLSTPRQYRHHHHHDHHHFRTRRRNRSEDQSIYSLEECTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWVNNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFCVEAANNGNAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKMEP 611
[Close]
BLAST of axis inhibition protein A vs. Planmine SMEST
Match: SMESG000025925.1 (SMESG000025925.1)

HSP 1 Score: 152.525 bits (384), Expect = 2.580e-38
Identity = 97/247 (39.27%), Postives = 142/247 (57.49%), Query Frame = 3 
Query:  234 VVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADR---EKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNSTSSDNSKSEN--LENQIQN----------NIFRDVDCSHVNYSVNNASNHVS----MKGKRERSIN--------SEIPTKANKSKQCASGL---NKDRRSIAEADPTSFVNQLNKRLEKV 884
            + +  +LL +S  V  FR +L+S  + H+L+FWFACQGFK+ DR    K++QL KVIYRAYIRSES  AVPL+ NTKK+IVDK+S ++C DQSIFDTAQ+EIRD+L  EF + F++S+    Y++  +   N  S N  ++ QI +          +I R    + +N   +  S  V+     KG  + S            I T  N +    +G    +KDRR+++E DP +F   L  +LE++
Sbjct:   37 IDNLSLLLQESDSVTNFRLYLDSINSGHFLDFWFACQGFKNFDRSDTHKLHQLTKVIYRAYIRSESPYAVPLKQNTKKSIVDKLSDRKCFDQSIFDTAQLEIRDILSGEFLMNFLQSD---FYIEPKSFERNLLSNNSRIQEQISDIPVSSCSSSGHIGRKSSSARINAIASRGSEGVNDGNCNKGSTDNSFGQLYTAQNTGTITTVFNNNLMGNNGSGTGSKDRRNLSEIDPQAFAKLLYTKLEEI 280

HSP 2 Score: 114.775 bits (286), Expect = 4.266e-26
Identity = 51/83 (61.45%), Postives = 64/83 (77.11%), Query Frame = 3 
Query: 1686 IIVGYYFCGDPVPYRTQVPIGESGFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEGKVVAKVEKME 1934
            ++VGYY   DPVPYRTQ+P  +   TLGQFK L+ ++GP+RYFFKR CDEFD  G V EE  +++ +LPLWEGKVVAK+EK E
Sbjct:  698 LVVGYYIGNDPVPYRTQIPDSQY-ITLGQFKSLVAKKGPFRYFFKRYCDEFD-CGVVHEEIIRDDAILPLWEGKVVAKIEKAE 778
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BLAST of axis inhibition protein A vs. Planmine SMEST
Match: SMESG000053355.1 (SMESG000053355.1)

HSP 1 Score: 70.4774 bits (171), Expect = 8.767e-14
Identity = 42/136 (30.88%), Postives = 77/136 (56.62%), Query Frame = 3 
Query:  180 VKVPTMEYVQTNQTDNPLVVDFKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKSA-DREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESF 584
            +K PT+E + + +         + +LND  G+  F  FL+SE +   L FW AC+ FK+   R+K+ ++   IY+ YI   S+  V L    ++NI+++++S    ++ +F+ AQ  I  ++ K+ Y RF+KS+ +
Sbjct:   52 IKKPTIENILSWKNG------LEFILNDYYGLYYFNEFLKSEYSVENLNFWLACEKFKTIQSRKKLDEIANSIYQEYIAIGSENEVNLDAKLRRNIIEQMNSP---NKKLFELAQSSIFILMAKDSYCRFLKSKCY 178
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BLAST of axis inhibition protein A vs. Planmine SMEST
Match: SMESG000027589.1 (SMESG000027589.1)

HSP 1 Score: 64.3142 bits (155), Expect = 8.915e-11
Identity = 37/119 (31.09%), Postives = 68/119 (57.14%), Query Frame = 3 
Query:  252 LLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQNS 605
            LL D  G+ +F  FL++E +   LEFW AC+ +KS + ++K+Y+  + IY  ++  ++   V L   T+   +  ISS     +  FD+AQ  I  ++ K+ Y RF++S+ +++  + S
Sbjct:  216 LLADRYGLALFNAFLKTEYSDENLEFWMACESYKSLSGQKKLYKEAQKIYSQHLSVQAPREVNLDSKTR---LQTISSLGTPSKMTFDSAQKRIFALMEKDSYPRFLRSDIYQIVYRES 331
[Close]
BLAST of axis inhibition protein A vs. Planmine SMEST
Match: SMESG000048981.1 (SMESG000048981.1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.442e-10
Identity = 34/121 (28.10%), Postives = 71/121 (58.68%), Query Frame = 3 
Query:  243 FKVLLNDSQGVEIFRGFLESERATHYLEFWFACQGFKS-ADREKVYQLIKVIYRAYIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEFYIRFIKSESFKLYLQN 602
            F+ LLND  G+ +F  +L+SE +   +EFW AC+ FK+  + +K+    + I + ++ +++   V +   T++  ++ I   Q  + ++FD AQ  I+ ++  + Y RF++SE ++  +Q+
Sbjct:  351 FEQLLNDKYGLALFHDYLKSEYSEENIEFWIACEEFKTITNPKKMASRAQKIIKDFVTTQAPKEVNIDSKTRQITLESI---QHPNANMFDMAQKRIQSLMEIDSYQRFLRSEMYQALMQD 468
The following BLAST results are available for this feature:
BLAST of axis inhibition protein A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AXIN13.090e-1854.22axin 1 [Source:HGNC Symbol;Acc:HGNC:903][more]
AXIN13.345e-1854.22axin 1 [Source:HGNC Symbol;Acc:HGNC:903][more]
AXIN24.458e-1738.33axin 2 [Source:HGNC Symbol;Acc:HGNC:904][more]
AXIN21.643e-1637.12axin 2 [Source:HGNC Symbol;Acc:HGNC:904][more]
AXIN21.731e-1637.12axin 2 [Source:HGNC Symbol;Acc:HGNC:904][more]
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BLAST of axis inhibition protein A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rgs-44.633e-724.79Regulator of G protein Signaling [Source:UniProtK... [more]
rgs-45.981e-724.79Regulator of G protein Signaling [Source:UniProtK... [more]
rgs-45.981e-724.79Regulator of G protein Signaling [Source:UniProtK... [more]
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BLAST of axis inhibition protein A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Axn3.415e-1244.30gene:FBgn0026597 transcript:FBtr0085554[more]
Axn3.415e-1244.30gene:FBgn0026597 transcript:FBtr0334703[more]
Axn3.571e-1244.30gene:FBgn0026597 transcript:FBtr0334702[more]
Axn3.614e-1244.30gene:FBgn0026597 transcript:FBtr0085553[more]
Axn3.614e-1244.30gene:FBgn0026597 transcript:FBtr0085555[more]
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BLAST of axis inhibition protein A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
axin21.015e-1936.84axin 2 (conductin, axil) [Source:NCBI gene;Acc:580... [more]
axin24.229e-1937.12axin 2 (conductin, axil) [Source:NCBI gene;Acc:580... [more]
axin24.229e-1937.12axin 2 (conductin, axil) [Source:NCBI gene;Acc:580... [more]
axin18.820e-1649.41axin 1 [Source:NCBI gene;Acc:57931][more]
axin18.820e-1649.41axin 1 [Source:NCBI gene;Acc:57931][more]
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BLAST of axis inhibition protein A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pak31.010e-1751.81p21 protein (Cdc42/Rac)-activated kinase 3 [Source... [more]
pak31.175e-1751.81p21 protein (Cdc42/Rac)-activated kinase 3 [Source... [more]
ampd21.761e-1733.78adenosine monophosphate deaminase 2 [Source:Xenbas... [more]
ENSXETT00000012979.13.121e-1633.33axin 2 (conductin, axil) [Source:NCBI gene;Acc:100... [more]
rdd23.988e-1131.82riddle 2 [Source:Xenbase;Acc:XB-GENE-6453154][more]
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BLAST of axis inhibition protein A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Axin15.736e-1947.22axin 1 [Source:MGI Symbol;Acc:MGI:1096327][more]
Axin15.736e-1947.22axin 1 [Source:MGI Symbol;Acc:MGI:1096327][more]
Axin15.882e-1952.08axin 1 [Source:MGI Symbol;Acc:MGI:1096327][more]
Axin21.185e-1536.36axin 2 [Source:MGI Symbol;Acc:MGI:1270862][more]
Axin21.464e-1536.36axin 2 [Source:MGI Symbol;Acc:MGI:1270862][more]
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BLAST of axis inhibition protein A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P57095|AXIN2_DANRE3.193e-1837.12Axin-2 OS=Danio rerio OX=7955 GN=axin2 PE=1 SV=1[more]
sp|O35625|AXIN1_MOUSE4.026e-1852.08Axin-1 OS=Mus musculus OX=10090 GN=Axin1 PE=1 SV=3[more]
sp|O70239|AXIN1_RAT5.312e-1846.30Axin-1 OS=Rattus norvegicus OX=10116 GN=Axin1 PE=1... [more]
sp|O15169|AXIN1_HUMAN1.484e-1754.22Axin-1 OS=Homo sapiens OX=9606 GN=AXIN1 PE=1 SV=2[more]
sp|O42400|AXIN1_CHICK7.460e-1751.81Axin-1 OS=Gallus gallus OX=9031 GN=AXIN1 PE=2 SV=1[more]
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BLAST of axis inhibition protein A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G3C7W80.000e+096.52Axis inhibition protein A OS=Schmidtea mediterrane... [more]
G3C7W96.049e-3539.27Axis inhibition protein B OS=Schmidtea mediterrane... [more]
A0A267DWY91.777e-2362.65DIX domain-containing protein OS=Macrostomum ligna... [more]
A0A0X3PP834.560e-2360.24DIX domain-containing protein OS=Schistocephalus s... [more]
A0A158QGK22.262e-2238.26RGS domain-containing protein OS=Rodentolepis nana... [more]
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BLAST of axis inhibition protein A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
axin21.407e-1836.36axin-2-like [Source:NCBI gene;Acc:103042974][more]
axin14.015e-1849.02axin 1 [Source:NCBI gene;Acc:103045152][more]
axin15.508e-1852.94axin 1 [Source:NCBI gene;Acc:103045152][more]
ENSAMXT00000043306.12.684e-1734.09axin 2 [Source:NCBI gene;Acc:103044632][more]
ENSAMXT00000049310.12.797e-1734.09axin 2 [Source:NCBI gene;Acc:103044632][more]
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BLAST of axis inhibition protein A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008444.17.420e-2051.90pep scaffold:Pmarinus_7.0:GL479496:14395:17295:-1 ... [more]
ENSPMAT00000009992.17.718e-1832.87pep scaffold:Pmarinus_7.0:GL486030:972:8629:-1 gen... [more]
ENSPMAT00000007682.11.743e-1747.67pep scaffold:Pmarinus_7.0:GL479837:661:11661:1 gen... [more]
ENSPMAT00000005690.11.830e-1730.77pep scaffold:Pmarinus_7.0:GL485422:2197:11231:-1 g... [more]
ENSPMAT00000009994.13.354e-1531.72pep scaffold:Pmarinus_7.0:GL486030:972:8338:-1 gen... [more]
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BLAST of axis inhibition protein A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of axis inhibition protein A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO448614.238e-1241.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328043.078e-1130.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373701.259e-931.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO379293.086e-746.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343517.818e-728.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of axis inhibition protein A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
axin22.435e-1737.12axin-2 [Source:NCBI gene;Acc:101159441][more]
ENSORLT00000012346.23.819e-1750.60axin-1 [Source:NCBI gene;Acc:101155494][more]
ENSORLT00000029383.14.217e-1750.59axin-1 [Source:NCBI gene;Acc:101155494][more]
AXIN29.814e-1737.12axin 2 [Source:NCBI gene;Acc:101156143][more]
AXIN29.814e-1737.12axin 2 [Source:NCBI gene;Acc:101156143][more]
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BLAST of axis inhibition protein A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000039725.10.000e+0100.00SMESG000039725.1[more]
SMESG000025925.12.580e-3839.27SMESG000025925.1[more]
SMESG000053355.18.767e-1430.88SMESG000053355.1[more]
SMESG000027589.18.915e-1131.09SMESG000027589.1[more]
SMESG000048981.11.442e-1028.10SMESG000048981.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30033656
GenBankADW27177.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033656 ID=SMED30033656|Name=axis inhibition protein A|organism=Schmidtea mediterranea sexual|type=transcript|length=2092bp
CTTGAAAGTATTAATTCTTTATGAATTGATAAATTTGTGACAATTTTAGA
GCATTTCATATGTAATTAATATTTAGCCAGCTTTCATTTTTTTCGTTTTC
AATCATGTCAGAATCTTTCTATCAAACCGAATCAGTAAATAGTCTTCCAT
TGTATTCAATACCTCAGTTACAAAATGTAGTAAAAGTTCCTACGATGGAA
TATGTTCAAACAAATCAAACTGATAATCCATTAGTTGTTGATTTCAAAGT
ACTATTAAATGACAGTCAGGGTGTGGAAATATTTCGAGGATTCCTCGAGT
CCGAACGAGCGACTCATTATCTTGAATTTTGGTTTGCTTGTCAGGGTTTC
AAATCAGCCGACCGAGAAAAAGTCTATCAACTAATCAAAGTAATATACCG
TGCCTATATTCGATCAGAATCGAAAACTGCTGTCCCTCTCCAGCCAAACA
CAAAGAAAAATATCGTCGACAAAATTAGTAGTAAACAATGTCTCGATCAA
TCAATTTTCGATACCGCTCAAATGGAAATTCGTGATGTGCTTATTAAAGA
ATTTTATATAAGATTTATCAAATCAGAATCATTTAAACTCTATCTACAGA
ACTCAACAAGTTCCGACAATTCAAAATCAGAAAATCTAGAAAATCAAATT
CAAAACAACATTTTTAGAGATGTCGATTGTTCTCATGTGAATTATTCTGT
GAATAATGCCTCGAATCACGTGTCAATGAAAGGCAAACGAGAGCGATCGA
TAAATTCTGAAATTCCAACAAAAGCAAACAAATCAAAACAATGTGCCAGC
GGTTTAAATAAAGACAGACGAAGCATTGCAGAAGCCGATCCAACATCTTT
CGTAAATCAATTGAATAAAAGACTGGAAAAGGTTCAGTTAATGCAACAGT
GCGGAATAAGTTTACAGCCAGACCAGAAAGTCGTGAACATTCATGTGGAT
CTTGTAAAAACGATCGACGATGATCCTGAATCAATTTTAGACAACCATTG
CTCTTTTCTGATGGACAGAGATTTGAACAAGAACGACCTTGTTGTCAATG
AAACTATAACCAAGAAAGACACAGATATACGATCCGTTGTATCTCAGGAC
AGTGGAGTTGCAACCACTTTTGATCCACAATGGCACAATAGACCTCCTTA
TTCACAACAAATATATAATCCATCTCCCTATATAAATCCACCGTGGCTTT
CTACACCTCGTCAATATAGGCACCATCACCATCATGATCACCATCATTTT
CGTACGCGTCGGCGAAATAGGAGTGAGGATCAATCTATATATTCTCTTGA
AGAATGTACTTCTAATCAAGGCCCGCCTTTCACGAGAAAAGGTAAAAGTC
AGGCCTCAGATGCTTCCAGTATTTTTGACTCAGGAGTAAGCTCAACTTAT
GAGCAGATCTCACATCCTTGGATGGTGTCCAGTGACAGGGTATCTAGTTG
GGTAAATAATCATCCAGGAATTGTTAATACTCCGGTCGAATTAACTGGTA
ACATGAAACGCAGTTGCTCAGCCCAAACGCCCGGGTACAAAGAGACGATT
AACGAAGGAATCGAGTCAGGGCCACCGGGTGAAGTTTGGATCGATGCTTT
TTGTGTTGAAGCTGCAAACAATGGAAATGCTTATCAAGAGAAAGTCAAGG
CCAAAGGCACCTGTAAAGGAAAAGGCGATTCAGTTATCATTGTCGGGTAC
TATTTCTGCGGTGATCCTGTGCCTTACAGAACTCAAGTCCCAATTGGAGA
ATCGGGCTTCACTTTAGGCCAATTTAAAATGCTTCTTCCAAGGCGTGGAC
CATATCGGTATTTCTTTAAACGCCCATGTGATGAATTCGATGGAGGAGGA
GCCGTCCAGGAAGAATATACGAAAAATGAAGATGTTCTTCCTCTGTGGGA
AGGAAAAGTCGTTGCGAAAGTTGAAAAAATGGAACCATAACAATATTTAA
TTGATCAATGTTTGGTTGCCTTTTTCGGTTCATTAGTTGTTCAAAACTAC
CGCCTTTCGTGAGTTGTTGCGATTGAGTGCAACTCGTTTTAGATGTCTGT
ACAAATTGAGTTGTATATTTCGTTAAATAAGATTGTTTTGGC
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protein sequence of SMED30033656-orf-1

>SMED30033656-orf-1 ID=SMED30033656-orf-1|Name=SMED30033656-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=612bp
MSESFYQTESVNSLPLYSIPQLQNVVKVPTMEYVQTNQTDNPLVVDFKVL
LNDSQGVEIFRGFLESERATHYLEFWFACQGFKSADREKVYQLIKVIYRA
YIRSESKTAVPLQPNTKKNIVDKISSKQCLDQSIFDTAQMEIRDVLIKEF
YIRFIKSESFKLYLQNSTSSDNSKSENLENQIQNNIFRDVDCSHVNYSVN
NASNHVSMKGKRERSINSEIPTKANKSKQCASGLNKDRRSIAEADPTSFV
NQLNKRLEKVQLMQQCGISLQPDQKVVNIHVDLVKTIDDDPESILDNHCS
FLMDRDLNKNDLVVNETITKKDTDIRSVVSQDSGVATTFDPQWHNRPPYS
QQIYNPSPYINPPWLSTPRQYRHHHHHDHHHFRTRRRNRSEDQSIYSLEE
CTSNQGPPFTRKGKSQASDASSIFDSGVSSTYEQISHPWMVSSDRVSSWV
NNHPGIVNTPVELTGNMKRSCSAQTPGYKETINEGIESGPPGEVWIDAFC
VEAANNGNAYQEKVKAKGTCKGKGDSVIIVGYYFCGDPVPYRTQVPIGES
GFTLGQFKMLLPRRGPYRYFFKRPCDEFDGGGAVQEEYTKNEDVLPLWEG
KVVAKVEKMEP*
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Aliases
The feature 'axis inhibition protein A' has the following synonyms
Synonym
Axin-A
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0016055Wnt signaling pathway
GO:0007165signal transduction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000044cephalic ganglia
PLANA:0000097ventral nerve cord
PLANA:0000103central nervous system
PLANA:0000136whole organism
PLANA:0000429neoblast
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR038207DIX_dom_sf
IPR036305RGS_sf
IPR016137RGS
IPR001158DIX
IPR024066RGS_subdom1/3
IPR029071Ubiquitin-like_domsf
Vocabulary: molecular function
TermDefinition
GO:0030159receptor signaling complex scaffold activity
Vocabulary: cellular component
TermDefinition
GO:0030877beta-catenin destruction complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016137RGS domainPRINTSPR01301RGSPROTEINcoord: 65..83
score: 36.61
coord: 93..116
score: 20.38
coord: 138..157
score: 36.09
coord: 43..64
score: 33.1
IPR016137RGS domainSMARTSM00315RGS_3coord: 46..164
e-value: 3.0E-25
score: 99.9
IPR016137RGS domainPFAMPF00615RGScoord: 47..161
e-value: 4.0E-23
score: 81.9
IPR016137RGS domainPROSITEPS50132RGScoord: 46..164
score: 24.514
IPR001158DIX domainSMARTSM00021dax_2coord: 525..610
e-value: 8.7E-21
score: 85.1
IPR001158DIX domainPFAMPF00778DIXcoord: 528..607
e-value: 1.1E-26
score: 92.5
IPR001158DIX domainPROSITEPS50841DIXcoord: 525..610
score: 24.102
NoneNo IPR availableGENE3DG3DSA:1.20.58.1850coord: 25..171
e-value: 2.0E-29
score: 104.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 370..393
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 399..418
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 370..384
NoneNo IPR availablePANTHERPTHR46102FAMILY NOT NAMEDcoord: 504..609
coord: 47..176
IPR038207DIX domain superfamilyGENE3DG3DSA:3.10.20.380coord: 525..610
e-value: 1.1E-30
score: 107.2
IPR036305RGS domain superfamilySUPERFAMILYSSF48097Regulator of G-protein signaling, RGScoord: 45..166
IPR029071Ubiquitin-like domain superfamilySUPERFAMILYSSF54236Ubiquitin-likecoord: 527..609