Protocadherin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033622 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 17Note: Hover over icons to view figure legend
Homology
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 251.521 bits (641), Expect = 2.322e-68 Identity = 217/733 (29.60%), Postives = 342/733 (46.66%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G + VD K GDI+ T ++IDRE + CQ P C+ + + + ++ E QIE+ DINDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G I + A D+DS N + YS+ + K F I+ G+I + LDRE ++ YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N +IY++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTF---HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLL--TPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810 HSP 2 Score: 136.346 bits (342), Expect = 9.800e-32 Identity = 141/582 (24.23%), Postives = 254/582 (43.64%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G N + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ T + Y + K+ IV + + S+ ++++++ D ND+ PV + + EN K ++ IT +D D G N+E SL + ++T E G Q+ + DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S K++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIG--HSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDY------EKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEP--AAKGLFTISPETGE----IQVKT----SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGE--TVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 819
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 252.292 bits (643), Expect = 4.971e-68 Identity = 217/733 (29.60%), Postives = 342/733 (46.66%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G + VD K GDI+ T ++IDRE + CQ P C+ + + + ++ E QIE+ DINDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G I + A D+DS N + YS+ + K F I+ G+I + LDRE ++ YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N +IY++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTF---HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLL--TPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810 HSP 2 Score: 135.961 bits (341), Expect = 1.330e-31 Identity = 140/580 (24.14%), Postives = 255/580 (43.97%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G N + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ ++ L+ +K + IV + + S+ ++++++ D ND+ PV + + EN K ++ IT +D D G N+E SL + ++T E G Q+ + DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S K++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIG--HSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFL-QTTTPLDYEKVKDYT---IEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEP--AAKGLFTISPETGE----IQVKT----SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGE--TVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 819
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 231.106 bits (588), Expect = 1.157e-61 Identity = 235/801 (29.34%), Postives = 367/801 (45.82%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISK---CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSP--LENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYIN 2526
++ E N IGNL+K LI N++ +T T F+L + + LI +++ G+I+ T A IDRE++C I + C + + ++ +++ I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ LEN Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y F + E+ R H +G + +D D G N + + I G I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P S + + + F NE+ N+ IN
Sbjct: 61 TIREEIPENVLIGNLLKDLNLSLIPNKSLTT----TMQFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA-------------YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDENDDFTID-SQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN-YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPD-SLFSVVIVNLF--------VNESVTNATLIN 815
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 230.72 bits (587), Expect = 1.366e-61 Identity = 234/802 (29.18%), Postives = 370/802 (46.13%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISK---CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSP--LENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYIN 2526
++ E N IGNL+K LI N++ +T T F+L + + LI +++ G+I+ T A IDRE++C I + C + + ++ +++ I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ LEN Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P S + + + F NE+ N+ IN
Sbjct: 50 TIREEIPENVLIGNLLKDLNLSLIPNKSLTT----TMQFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA-------------YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN-YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPD-SLFSVVIVNLF--------VNESVTNATLIN 804
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 230.72 bits (587), Expect = 1.366e-61 Identity = 234/802 (29.18%), Postives = 370/802 (46.13%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISK---CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSP--LENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYIN 2526
++ E N IGNL+K LI N++ +T T F+L + + LI +++ G+I+ T A IDRE++C I + C + + ++ +++ I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ LEN Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P S + + + F NE+ N+ IN
Sbjct: 50 TIREEIPENVLIGNLLKDLNLSLIPNKSLTT----TMQFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA-------------YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN-YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPD-SLFSVVIVNLF--------VNESVTNATLIN 804
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 163.696 bits (413), Expect = 2.578e-40 Identity = 204/761 (26.81%), Postives = 337/761 (44.28%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHNGQI-HLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRS----RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL--TNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++PI +I ++ S++ L + +S ++L ++D G+I + ++DRE + + I K ++ I A + + ++D+ DN P F+ D +I E+ + A+D DS + G S+ +N + N + ++ LDRE + + ASD G + + +VEIT DVNDN P + Y I E T A + + A D+D G++ + ++ +S + + + E L I A K + + V+ A DG + +T+ L I D NDH P + + ++EN V R+ DED G N S+ + +D E+ G K +L DRE +RYS++V D GTP++++S I + + D NDN P F+ + +ISE+ G +I + A D+D + ITY I D EV I G I ++ L R+ + + A D G L C + + + DVN +S KI E H IG L A D D G N + + S R P + G I ++DRE V+V D+ +PP +T + + + D+NDN P+FT A I++D+ G+ +V A D D G NG + Y L ++ + + LF + ++ G + + KLD + L + ARD+GTPSLSA + + +
Sbjct: 177 DTPIETIIASVKASHASSQPLYYSMVAPQDSRS----QNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVV---VHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENG---EIEYSLGEGNGKNLLAI----NAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDED--FGTNGKVHYSMASSSGIGGLTID-YSTGEVTLRERIDA----KNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIID-------EDSGLIKTTKL-------LDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQG--GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPE-------HSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDP------SSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAA----TISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITL 880 HSP 2 Score: 139.813 bits (351), Expect = 6.319e-33 Identity = 158/610 (25.90%), Postives = 257/610 (42.13%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEIS-ECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI--------IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV--RSRSTPIDIQVYNEG----KIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDED 2262
L I +IDIND+ P+ +K I + ENVA E A D DS G+ S E++ +ID + + ++ LDRE + + A D G I V + D+NDN P + Y IS E ++++ L A D D+ Q +I ++I E + + I I + L++ +++K + + A D G + + I D N P H S+KI E+ V + D D+G N+ S++ + F +D + G + DRE + +SV V +D+ +P +++S I + + D NDN P F + +ISED +G V A D+D PN I+ Y + I + + T +G + ++ LDRE + A+D G P+L+ + +I + + DVNDN P SY I E+ +G + A D D G N FR+ + + DI+ E +I+ D E +G ++T V I V DVNDN+P ++ +N D++ +G + A D D
Sbjct: 465 LTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGI-----IKYSMEGSEDF--IIDEDSGL---IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ----KITYRIEEADRE---VFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDP-------SSGDISVSS-------DLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRT-----SGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGST---VGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQ--LSSTVPVRIHVSDVNDNKPALKDFVI----LMNRFDNVQMARQIGFIPAFDPD 1028 HSP 3 Score: 104.375 bits (259), Expect = 3.489e-22 Identity = 98/319 (30.72%), Postives = 154/319 (48.28%), Query Frame = 1
Query: 1519 NPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLN--ASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
N HF+ E + ED I I V A + S P + YS++ D + F ++ +G+I L K +DREV D++ V A + +P ++ S + + VLDV DN P F + RE L+ A D D G+NG + + + + + G I +DRE + I + V D G P R +T V I V+DVNDN P F N + I +++ +++ VKATDEDFG NG + Y++ + + L S G++ L++++D K +P V+ A+D P+LS+T L I
Sbjct: 161 NAVHFQQEKYVKELPEDTPIETIIASVKASHASSQP---LYYSMVAPQDSRSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEI----REDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYN----VTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKN-SPITAVIRAKDGAQPALSSTVPLTI 467
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 154.836 bits (390), Expect = 1.578e-37 Identity = 166/586 (28.33%), Postives = 259/586 (44.20%), Query Frame = 1
Query: 739 LDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTT-EAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-LYFDREKASRYSVEVICNDNGT-PTMSSSEI-ITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMA-AGS----IVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFK 2469
D E KS++ + A++ I + + DVNDN P + Y + E E +L ++A D D G++ + I S ++ I +T + A K + +VV A DG G+S+E + + I + + S +I+ E D GI +++ + S+Y+ G Q F ++ G +Y R + V+ N T P+ S++ + IFI D NDNPP F + SI ED K+ +V A D D N + YSII + GQ+ +LD E Y+ V+A D G P + + + I VLDVNDN PE S+ +E E +GK+ A D+D +NG +R+ + S I G + +IDRE + +D+ + D G PPR++T + I VLDVNDN P + L+IT + AGS +G + A D D GLNGS++Y Q+ LF ++S+G + L+++L+ + RL V DQG P S + +R K
Sbjct: 601 FDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMD--SGTFGEVSYHILSESSSFS----INPVTGEVF-----AQKPLARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTE------------DILPGIAIGSVGAMSKVKY----SIYS-----GDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSW--YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGID-EKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPP----------SCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQS---SLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRISK 1138 HSP 2 Score: 107.842 bits (268), Expect = 3.258e-23 Identity = 128/541 (23.66%), Postives = 236/541 (43.62%), Query Frame = 1
Query: 736 DLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIK--VHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDR---EKASRYSVEVICNDNGTPTMSSSEIITIFISD-ENDNPPHFE-TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSR-----------STPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHI--EVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+LDRE ++ + + + G G Q R+ V + ++NDN P + R+ + V + A+D D+ + F +S++S I T +I ++ A F+ + I A T + + + D ND+ P ++ +++ + +I D D + SL G IF++ G F + RY V V DNG P+ S+S +++ I + E + P FE EF+ F + E++KIG +IG + ++S + I D E + F I+ G++ + +DRE + +EF VE + + CK +IVLD NDN+P S +Y + +S K IG++ ASD+D G+NG +R+ S + I + +N+ ++ F N + +LV+ D+G+P R A V + ++ + + P F P+ H + +D + G+++ +++A++ N ++Y+L
Sbjct: 1887 ELDREILERYSLKVIGT-GSGQQIGTRVDVRVNNLNDNVPSFPMSKPRRVPENLRVGSYVATVGAKDVDN---LAPLRYFLVSDSSGQTPTHFNIDQFTGTI---HLTAPLDFEVLPEHTLTIKATDGSFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPF-AKIEAHDLDA--RGALTYSLGQ-----------------GSSSIFRVAPESGALFMKVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFR-FEVMENSKIGLQIGNLSGEESRE------FHYRIQDPEASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQK---IGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQ------ILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVH----VLEDTSVGTVLQKIRASNRLGMRNDGLLYSL 2380 HSP 3 Score: 101.293 bits (251), Expect = 3.054e-21 Identity = 174/752 (23.14%), Postives = 311/752 (41.36%), Query Frame = 1
Query: 127 LMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNN--INPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRP----VIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEV----KETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
L+F + + +F + ++F+V E Q IG I I K E K F + ++ + + VD++ G+I + +D E+ + + + + ++ +E+ D NDN PSF ++I E + F+LP D D K+ V + I N F+L N + L V G LDRE +E + A DGG G+ R +EI D NDN P + Y +S + + ++ + A D D IG +I + I + S F I++S + +L + ++V+A+D S+ + + + P + V S+S + EN +V R+++ + DT + S P + Q ++ L + G+ DRE AS + ++ + +G + +++T I D NDN P + + S++ + AKD D N I YS++ D E+ KET G+I + +D + +F V A+D G P L+ ++ +LD P+ + VE E + K+ A++ G + R+ ++++ + + + G + D E K + N N T+T+ + I + DVNDN P F YP N + +L + + + V A+D D G G + Y++ +++ + FSI
Sbjct: 10 LIFSLIFLIFPTFCQCLTKFTVP-----ESAQ-----IGTRIGWISG--KREESAAPKYFVVFPDEQTS---KFLKVDERSGEISTIAHLDYEKRSK-------FDIVAVKVEESGETIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDV---HRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDAD----IGENSRISYDIKKTSAPSN---SNFAISQSGVITTTASL--LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQ-----------YRDTKLRLIGSSALCP-QQTDQAHVYLL-LLCGI-LDRETASEHHLKFLLEKDGQIIIEHPQLLT--IGDINDNAPQWHSSQIHISLNRTQGGSRTL---TAKDPDLGQNGWIRYSVL-DTELVSIDKET------GRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEK--ALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEHLTVDTMS-GTVCIQKTFDFE-KQKSYQTTVIATNAN-SETSTSLISIRLKDVNDNWPIF-YP--NEY-HLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS---FSI 689 HSP 4 Score: 83.5741 bits (205), Expect = 9.402e-16 Identity = 137/611 (22.42%), Postives = 243/611 (39.77%), Query Frame = 1
Query: 682 FELIDHGNNINPYLRVIGDL---DRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDA-KIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHT------KDLFSIQ----SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
FEL++ + + GDL +++S++ L D G +EI++ N T L + K+ T + + + K P+ G + + I E + + V +E ++ N+ + E + S+ VI G G+ T +++ + + ND+ P + S ++ EN + V + D D + F+ DS +P F ++ G D E +++ + D T ++ +TIF+SD NDN P F ++S G + A D D+ +TYS+ F + K+L +RY TV A DNG P+ + S + +I+ + F+ E E IG L+ ++ F +R++ + G++ G IDRE+ + V++ + + H+ VLD NDN P FT + YL++ D MA G +G++ A+D+D G NG + Y + + N D SIQ +D Q+ +++VEARD G P+ +A + +
Sbjct: 1765 FELLEDSSGSLDLVPETGDLVLRRLSSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQPELAG--LTYSIVEGNIDSAFSVD----SEGVIRTNLELDREILE-RYSLKVIGT-GSGQQIGTRVDVRVNNLNDNVPSFPM-SKPRRVPENLRVGSYVATVGAKDVDNLAPLRY--------FLVSDSSGQTPTH-------FNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFDTFTN---LTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSL--GQGSSSIFRVAPESGALFMKVLP-PAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRF-EVMENSKIGLQIGNLSGE-----ESREFHYRIQDPEASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFT----SVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATW------QILVEARDHGHPARAAVGKVQV 2327 HSP 5 Score: 82.8037 bits (203), Expect = 1.386e-15 Identity = 139/635 (21.89%), Postives = 260/635 (40.94%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGN------NINPY---LRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA--KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIK--VHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKD----RYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE-----HKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHT 2313
+ + + ++NDN PSF P K ++PEN+ S + AKD D+ YF + D NI+ + + + LD E + + A+DG + + + ++D+NDN P + Y+ +S T ++ A D D G + + + + S + IF + L + L E + + V A D S T++ + + + P K + + + E SKI + ++ E+ + EF + D KIF ++ L+ DRE+ + + +V ++ + + + DENDN P F + S+ + G +IG ++A D DS N ++Y I+ ++ G I LN+ D ++ + ++ VEA+D+G P K++ V+ + S S F ++ +E + K+ AS+R +N + ++ + I V G++ ++D E I + + V +GN R+A + I V V++ P FT + L I AG VG+++A DED G++G + Y+++++ T
Sbjct: 1913 VDVRVNNLNDNVPSF-PMSKPRRVPENLRVGSYVATVGAKDVDN---------------LAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFDT-FTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD----ARGALTYSLGQGSSS------IFRVAPESGALFMKVLPPAGE-RYLVTVTATDNGVPSFSTSVPVSVI-IGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEE---SREFHYRIQDPE----------------ASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQ-----VSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDV-KTGELTLKTHLDWESEPIISMYLSVS-DGNG-RSAVVPLKIVVEPVDEFAPVFT----KSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQST 2487 HSP 6 Score: 72.7886 bits (177), Expect = 1.441e-12 Identity = 97/370 (26.22%), Postives = 151/370 (40.81%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKA 2250
L I D ND+ P + HSS + I N +++ +T D D G N S+ DT VS+D E G +IF N+I D S V D G+P +S+ + + D PP FE I ED IG + V+A +S + I YS+ E ++ +G + + K D E + Y+ TV A + IR+ DVNDN P Y + E + E + +ASD D G G + + S S+ I G++ + R + ++V D G + +HI V+D + P+F+ + + T+D+ G +G V A
Sbjct: 429 LTIGDINDNAP--QWHSSQIHISLN-RTQGGSRTLTAKDPDLGQNGWIRYSVLDTELVSIDK------ETG---RIFVPNTI-----DCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQ---DEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRL--KDVNDNWPIFYPNEYHLTVREGPKPEEPLLVV---SASDMDSGTFGEVSYHILSESSSFSINPVT-GEVFAQKPLAR---GRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFS----RSKYEIRTTEDILPGIAIGSVGA 765 HSP 7 Score: 54.6842 bits (130), Expect = 5.187e-7 Identity = 144/665 (21.65%), Postives = 248/665 (37.29%), Query Frame = 1
Query: 343 HLISVDQKKGDIWVTSAID---REEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDH--GNNI-----NPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVL-QLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIV--VIAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDR------EKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS-RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDED 2262
H S+D+ G I+VT +D + + I L N ++ I I D NDN P F I I E++ F + A D+D +K G E + +I G++I L LD E ++++ + A+D G + + + DVNDN P++ Y E+ E + ++ ++ A+DKD + GQI ++I+ S+ F I E + N+ +S S V I A+ +G RS+ + + + D ND+ P + + + + + I D D+G+N +Y + L Q +F + S +Y R E+ R S VI +D G P S + + IS + + E K I + G + + A ++ +I E+ F I ++ + R Y + D + S ++R++ N E + +I +S K IG+L D G+F +R S S P+++ G ++Y + R N V +E+ ++P+F H +NI +D GSI+ V AT D
Sbjct: 780 HNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGESNQT--------QVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNG--------------EVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLEN--GQIVYRITNGSE-------YFGIDEKL--GNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSC-LSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSV--------------LYRAQL----QSSLFVVKSNGDVYLRRQLNASDERHQRLS--VIVSDQGVPRKSVVCHVPVRISKGSADIQIQEPFQKYIEIPKSCPTGCRLTTLNATG--------VSSWLIQSSEISNHFAIREGVLFMISHPIHRP---PYSLVIVLSDKN--DRQKSIQLRVLASGEAANKEE-----TIRISDSNSIGTK---IGRLGEKSAD----GSFFYRFSSEESCPLELD--QTGGLLYLADGLRRGDTHNFSCFFEKFNTTDGSAEEMRVDLEISRTKSDKPRFD----TGHLRVNIREDTPTGSIITTVNATVSD 1359 HSP 8 Score: 53.5286 bits (127), Expect = 1.195e-6 Identity = 31/84 (36.90%), Postives = 43/84 (51.19%), Query Frame = 1
Query: 1720 LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV 1971
LDRE + + D G + NDSC +R+ V D NDN P++ S ++ E E + + ASD DIGQNG F F +
Sbjct: 1687 LDREASQEHLLIIILTDGG--SRNDSCTVRVTVADQNDNKPQLDASTPSEL-EIAESSRVGDVLHRFRASDMDIGQNGKFSFEL 1767
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 139.043 bits (349), Expect = 8.582e-33 Identity = 158/610 (25.90%), Postives = 257/610 (42.13%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEIS-ECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI--------IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV--RSRSTPIDIQVYNEG----KIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDED 2262
L I +IDIND+ P+ +K I + ENVA E A D DS G+ S E++ +ID + + ++ LDRE + + A D G I V + D+NDN P + Y IS E ++++ L A D D+ Q +I ++I E + + I I + L++ +++K + + A D G + + I D N P H S+KI E+ V + D D+G N+ S++ + F +D + G + DRE + +SV V +D+ +P +++S I + + D NDN P F + +ISED +G V A D+D PN I+ Y + I + + T +G + ++ LDRE + A+D G P+L+ + +I + + DVNDN P SY I E+ +G + A D D G N FR+ + + DI+ E +I+ D E +G ++T V I V DVNDN+P ++ +N D++ +G + A D D
Sbjct: 106 LTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGI-----IKYSMEGSEDF--IIDEDSGL---IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ----KITYRIEEADRE---VFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRID-------PSSGDISVSS-------DLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRT-----SGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN---SPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQ--LSSTVPVRIHVSDVNDNKPALKDFVI----LMNRFDNVQMARQIGFIPAFDPD 669 HSP 2 Score: 136.346 bits (342), Expect = 6.530e-32 Identity = 163/564 (28.90%), Postives = 254/564 (45.04%), Query Frame = 1
Query: 820 IVEIT--DVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHNGQI-HLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRS----RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL--TNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+VEIT DVNDN P + Y I E T A + + A D+D G++ + ++ +S + + + E L I A K + + V+ A DG + +T+ L I D NDH P + + ++EN V R+ DED G N S+ + +D E+ G K +L DRE +RYS++V D GTP++++S I + + D NDN P F+ + +ISE+ G +I + A D+D + ITY I D EV I G I ++ L R+ + + A D G L C + + + DVN +S KI E H IG L A D D G N + + S R P + G I ++DRE V+V D+ +PP +T + + + D+NDN P+FT A I++D+ G+ +V A D D G NG + Y L ++ + + LF + ++ G + + KLD + L + ARD+GTPSLSA + + +
Sbjct: 1 MVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDED--FGTNGKVHYSMASSSGIGGLTID-YSTGEVTLRERIDA----KNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIID-------EDSGLIKTTKL-------LDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQG--GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPE-------HSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDP------SSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAA----TISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITL 521
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 117.087 bits (292), Expect = 6.023e-26 Identity = 206/790 (26.08%), Postives = 344/790 (43.54%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTK-SFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFAD-----HQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXEN-YFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKD-DPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALK--SFKENKA--SIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSI------SEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGN-IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLN-ITDDMAAGSIVGEVKATDEDFGLNGSIIYNL-----TNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD---SFDRSNENSM 2508
++ +GN+I +Q TEI + + + SE+S+++ SV++ G I V S++DRE Q I AD H I + ++I D+NDN P+F D + I E+ A + ++ A DRD G + S + EN YF+L N + +L V LDRE I ++ A+D GG + ++DVND+ PQ+ + ++ +T + +L + +D D P + +F I + ++ +F+I + N LK ENK + V A DG ++ T +++ +K D + ++ + EN K +V + G N F S ND N ++ NG I ++ + +++ + + + DN + E+IT+ I + NDN P + SI SEDA+ I ++A+D+D I + ++ D+ F I+ NG + + K LD E+ + TV A D GE D I + V+D NDN P S YS K++ES E + + AS D QN T + ++ + + + I+ +D E + + + V D+G PP V I V+D NDN PKF Y+ + ++ +G V VKA D D G++ Y L T + F+I S+G +++ + +D + L V A+D G P L + L I D +FD N ++
Sbjct: 2620 DADVGNVIGRVQQM--ETEIDEIRFTIVPGSEESDSF--LPFSVERSTGKIIVKSSLDRERKNQ----------WKMTIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSG------RIRFSLVEENPYFDL----NENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLHLPST-SPILHFSIKDDDLSPNNVS---QFFIPKGNEE-----GVFWIDSN----NDLLLKRPEIVENKMQYQLKVTAFDGVFETS-TKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVVLGESSL---LGPNVTFKLSDNDGN------VFVVNFRNG----IVKVKESDQIDYEKNQQLEFH-RLTIQDN---SEVCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDAR--QYITRIVAEDADFDE---IKFRMVDDF--GGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASD-GE--FEDKATILVTVIDQNDNAPTFEKSTYSMKVMES---ESIGYELAHFRASGGD--QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKF-----EKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTAL 3334 HSP 2 Score: 103.605 bits (257), Expect = 7.308e-22 Identity = 166/609 (27.26%), Postives = 261/609 (42.86%), Query Frame = 1
Query: 823 VEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYF--------DREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEF----KTFSISEDAKIGHEIGIVIAK---DSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDN-----GEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGT---FRFRVRSRSTP-----IDIQVYNEGKIIYFG--NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYF-----KPRDSFDRSNENS-MNSKYINP 2529
+ I DVN+++PQ+ + Y ISE K + ++ A D D G+I+F + N+Q ++ I T + L +L ++ + +IA+D EG R + T + + ++D ND+ P V S +I E+ V+ + DED G NS+ LN +K F+++ G F D K +++ + D+G P +S+S + + + D N H EF K S+ E+++IG E+ ++ AK D + Y IIG + F I+ G + +LDRE K Y TVEA+D+ +P D + I +LD ND+ P I E + I K+ A+D D N F++ R P ID+ G I G +DREK + ++ V + D G P + V + VLD NDN P FT + H+Y ++ A + + A D D G N + YN+T + FSI ++G II + + L V+A D GTP T + KPR S + E S S Y+ P
Sbjct: 708 LRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGN--NGKIKFSLG-NNQEKSSVISIDAKTGIVKLLK--SLDREDQDVHTFAIIASD-EGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLN------------------SEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHN--HLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGG-DGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRP--VAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIE-RGDPQSFFRIDL---TSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAI---HHY-SVRSKFAGK--LCRIFAVDADEGENARLTYNITEGDAR---FSIDNNGNIIASEAIHGDESYA--LTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIP 1272 HSP 3 Score: 102.449 bits (254), Expect = 1.473e-21 Identity = 116/431 (26.91%), Postives = 182/431 (42.23%), Query Frame = 1
Query: 703 NNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS----IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNI-ITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKI-VESWEREHKHFYIGKLNASDRD-IGQNGTFRF 1965
++IN + V+ LD E + F + ASDG + K I+V + D NDN P + Y ++ E + ++ A D +TI ++ + N I + + + + + ALK + V+A D E +E+ + D ND+ P + K+KEN KS V + D D + F + VS + T L F +NS + D EK +Y+++VI D G P + S ++ I + DEND+ P F+ T + E IGH + D D N T I GD ++F +N ++ K L+ KD+Y TV AKD + C + I + + + P T KI + + + E IG+L ASD D QNG RF
Sbjct: 3062 DDINGVVTVVKPLDSEILGFFNLTVVASDGEF-EDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALK--------LTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVD---SEHFGAVSYELEIVSETTTDTPVLP-------FAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDG--AKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTD--CPLTIFIRQTSRHAP---TMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRF 3466 HSP 4 Score: 100.523 bits (249), Expect = 5.735e-21 Identity = 110/417 (26.38%), Postives = 184/417 (44.12%), Query Frame = 1
Query: 739 LDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE---CTTEAK--VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLND-TNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKET----FGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGT 1956
+D E + EFH K I V I ++NDN P+ + + I E + +A+ + ++ A+D D +I+F++ ++ I I + + L+ L F ++ V+A+DGE ++ TI + + D ND+ P + + S+K+ E+E + + DQ E+ +D T+FV+L++ Q I L D E S + V+ D+G P + + + I + DENDN P FE E + E++K G ++ V A D DS ++Y + I +T F IN NG + +++ +D E +Y V AKD G P L + I V D ND+ P +V+ E E + K + SD D +NG
Sbjct: 2971 IDYEKNQQLEFHRLTIQDNSEVCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDAD-----FDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFF-----NLTVVASDGEFE-DKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNA----------QTGILTLAK----PLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQ--EGEAIGHRLLKFSVSDLDGPKNGA 3360 HSP 5 Score: 97.0561 bits (240), Expect = 7.593e-20 Identity = 136/535 (25.42%), Postives = 227/535 (42.43%), Query Frame = 1
Query: 712 NPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR--IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVL-QLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD-GEGRSNETTIELEI-----------------KDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGN--IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNIT-DDMAAGSIVGE 2241
N LRV ++R + + F + AS G N+ + +EI D ND+ P + R+ VL +++A D+D+ + G+I +K + E+ + I T I + + K N V A D G S + + L + N H PV +++ E+ +V ++ DED G N ++D S + + E G+ I + + L ++ + ++V D GTP SS + + + I D N++ P F+ ISE+ K G +I V A D D N I +S+ + E I+ G + L K LDRE +D + F + A D G P + I V DVNDN P+ +S + + H F + + A D DIGQN +F + S P I ++ I+ +D K ++ ++V D+G+P + + +H+E++D+ AHN+L I DD+A + V E
Sbjct: 442 NGILRVSAKINRSE-RVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGE--NGKIVYKFTS-----ELPLEINANTGEITLVEVPK----KGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVD--EQSGE--ITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPE-DLPHGAF-VSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDI-------------AHNHLAIEFDDVAKEASVYE 945 HSP 6 Score: 87.4261 bits (215), Expect = 6.597e-17 Identity = 169/749 (22.56%), Postives = 302/749 (40.32%), Query Frame = 1
Query: 190 VKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTK-SFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEII-------DINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEIS-----ECTTEAKVLQLNAQDKDDPQTIGGQ-IRFKI------SENSQNYEMIVRIFYI----TESILYLNIGALKS----FKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-------FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVN----------DNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
V YL + EN+KP ++ K+ N K K S EKS+ +IS+D K G + + ++DRE+ Q + + I A + F +++ + D+NDN P +IPE++ + S A D D K E IDH + LD F + +D G C + VE+ D+ N KE S E TE V+ + A++ D Q + + + ++I S + + VR ++ T+S ++ + A S +K+ + R + + + I D NDHRPV K + EN + +++ ++ E + + + N + M+ +E G + F+++ G DREK S + + V D G P + S+ I+ + + DENDN P F +S+ +K ++ + A D+D N +TY+I E F I++NG I ++ + + + Y TV+A D+G P + +VL N ++ PEIS S ++ + + +GKL ASD D G + + D++ + G+++ ++ L + +G +TV I+V RPKF+ +H ++++ +A G+ + +KA+ E G +++NL
Sbjct: 723 VSYYLRISENEKPGK---DIFKVTANDFDGGNNGKIKFSLGNNQEKSS-----VISIDAKTGIVKLLKSLDRED--QDVH--------TFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDED------IGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTE--VIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPR------------RRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKV-----------EATDADDVDNDAAAPLMFK--IERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVR--SKFAGKLCRIFAVDADEGENARLTYNIT---EGDARFSIDNNGNIIASEAIHGD--ESYALTVQATDHGTPGQQFAAT--RVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDAD-GDELWWSISSGDPDSVFDVR-QDTGQLLLAKKVEL-LKRGELRLNISVTDGQA--WDHSTVIIQVSRQISQRPKFSA----SHYQTDVSERVAVGTQIYTLKASGESLGTK-PLVFNL 1401 HSP 7 Score: 85.1149 bits (209), Expect = 3.304e-16 Identity = 95/377 (25.20%), Postives = 158/377 (41.91%), Query Frame = 1
Query: 757 KSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKA----SIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGIN--SEFSCSLNDTNFVSL------DSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE 1845
K ++ L D G + + + + D+ND P +V Y ISE E V+ ++A D D+ TI + SQ + + R IT + E+KA S+ + A D + T +E+ + S S+K+ S L + + D I + +++ F + DS +E K I + + DRE+ +++ + + + G + + +T+ I D NDN P F +++ F+ISEDA +G + I A D D SP+ I +S++ E F +N N G + + LDRE D Y+ A D G N I+V DVND+ P+
Sbjct: 2471 KRYQIPLVVEDATGRRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTI--EYSLLDGSESQFFSVHPRQGTIT----------VAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVN----------IASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSS------LDRERKNQWKMTIRADAAGG--VHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLV---EENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEG--GFNTDLPFTIVVSDVNDSPPQ 2812 HSP 8 Score: 76.6406 bits (187), Expect = 1.075e-13 Identity = 91/379 (24.01%), Postives = 158/379 (41.69%), Query Frame = 1
Query: 1060 ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGI----NHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYS-FKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKF 2166
L ++ + I ++ D GR +T+ L + D ND P + S I E+ K V ++ TD+D+ E+S L +G + + F ++ G + + S+ + D+ P ++ + + I+ E+ P F FS+ EDA +G+ IG V +++ I ++I+ E ++F G+I + LDRE K++++ T+ A G ++ + + + DVNDN P Y F I E + +A DRD +G RF + + D+ N G + +DREK+D ++ D G T I V DVND+ P+F
Sbjct: 2464 VLNYHRDKRYQIPLVVEDATGRRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYS------------------LLDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDE---IRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAG--GVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTS---VTIFSAMDRDDSPSGRIRFSLVEENPYFDLN-ENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFT--IVVSDVNDSPPQF 2813 HSP 9 Score: 69.3218 bits (168), Expect = 1.900e-11 Identity = 67/267 (25.09%), Postives = 127/267 (47.57%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPV-AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEI--TDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQ 1272
+++I ++D NDN P F+ ++ K+ EN ++S E L V A D DSE +G Y L+ +S + + ++ N N + + +D E IK + + A DGG + ++EI D ND+ P + + E ++L+ + D D P+ G +I + + F + E + L L+ K++K + VIA D +G++ + + + I+ + H P +K + +NE + ++ R+ +DED+
Sbjct: 3201 QVEISVMDENDNAPKFEKEKYVGKVKEN-SKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDT--PVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKN-GAPFTVEIQGDG------AKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDE 3457
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: cdh-3 (Cadherin-3 [Source:UniProtKB/Swiss-Prot;Acc:P34616]) HSP 1 Score: 103.219 bits (256), Expect = 8.367e-22 Identity = 170/664 (25.60%), Postives = 275/664 (41.42%), Query Frame = 1
Query: 346 LISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFS--LPVAKDRDSE-KYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEI--TDVNDNTPQWVGLPYRKEISECTTEAKVLQ-LNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICN---DNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAK---IGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN 2301
L +V+ GDI +DREE + + L A + I + ++ I + DINDN P F+ IKI EN S+ L KD+D+E +Y ++ +I F + N ++ V G ++RE + F F + +DG + ++IVEI D NDN P + + T +++ +N D D + + S+N E+ LKS + + V +D G H PV ++ ++E+++ ++ V + D+ S+ S + LE I + S D E+ S V +I DN +S+ TI I D NDN P F+ + F+++E++ IGH VIA+D D S + Y I+G + F + +GQI + LDRE K Y VEA D+G+P + + + VLD +DN P S + ++ E + +L+ASD D N F P + N G + ++D EK + V + D T++ + V DVNDN P F P YL I+++ +A +G+ A+D D NG I Y++T+
Sbjct: 1698 LFAVNSTTGDILSLIPLDREE--SSLHELLIEA-KDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKDAELQYSLESNDEITIP-------FRI----NVATGWITVAGKVNREENEEFRFFVKVTDG---EKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHVINVHDLDKSDHLKFSLNNSNLNLSENGEI-----------------TLKSPLQTAVPVRVTVSDDAGHVAFMEYLFH-PHSRKHFPVFVEKLDTVSVREHDEQELAVFKAN----------------GDSIRYSIVSRCSDHLEMEKSTGILKTKS----SLDAEEYSECLVFIIATTYFDN--KPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGH----VIARDIDRSSR--VFYEIVGG-DANHEFMVTESGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEP---VIQLSASDADEHSNHRFELDGGGEGIPFRVD-ENTGMVFVNDSLDFEKKQSYRIKVKLTDGA---WLIETSLFVNVKDVNDNAPIFEKP-----EYLFISEENSAE--IGQFHASDMDSENNGKIRYSVTS 2283 HSP 2 Score: 81.2629 bits (199), Expect = 4.080e-15 Identity = 79/278 (28.42%), Postives = 129/278 (46.40%), Query Frame = 1
Query: 1141 IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGI-NHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-----TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGT 1956
I +++ D ND+ P+ + ++I E V TD D+G N + ++D+M SP Q F + G DRE YS+ + D G P +SSS + I I D NDNPP+F ++ +++ + ++ + A D DS+ N+++TY I+ E F I + N + N + E R EF VEA+D+G P L+ + I + + N++ P I+ + Y F IV+ + K I + SD +G N T
Sbjct: 103 ILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTM--SPF-GIVQSDGFLFLEVTG-KLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDENILVTQN---NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANST 371 HSP 3 Score: 72.0182 bits (175), Expect = 2.567e-12 Identity = 79/295 (26.78%), Postives = 131/295 (44.41%), Query Frame = 1
Query: 1489 ITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNII-TYSIIGDYEVKET---FGI-NHNGQIHLNKI--LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFT---YPLLNAHNYLNITDDMAAGSIVGEVKATDED--FGLNGSIIYNLTNQNHTKDLFSIQS 2337
I I + D NDN P F + + I E A IG + I A D D N I Y ++ +T FGI +G + L LDRE +D Y + A D G P L+ SC + I++LD+NDN P + +W + + LNA+D D +N +R+ ++ ++ I+ N + E + + + +V+ D+G PP + T + + + N++ P YP + + ++ + + G + + TD D G N +I N+ L S QS
Sbjct: 103 ILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIR---SLTLNWN-GLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDENILVTQN-NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYP--SDYPFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQS 390 HSP 4 Score: 70.0922 bits (170), Expect = 1.151e-11 Identity = 55/169 (32.54%), Postives = 85/169 (50.30%), Query Frame = 1
Query: 1360 GQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI 1848
G +F +NS G + DRE++S + + + D G P++S++ I I + D NDN P FE ISE++KIG +I ++A D D + YS+ + E+ F IN G I + ++RE + + F V+ D GE + + I V D NDN P I
Sbjct: 1694 GNTSLFAVNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKDAE--LQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKVTD-GEK--SSKVIVEIHVEDFNDNHPMI 1857 HSP 5 Score: 65.0846 bits (157), Expect = 3.590e-10 Identity = 80/292 (27.40%), Postives = 117/292 (40.07%), Query Frame = 1
Query: 118 LFGLMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTY----GRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENY--FELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTP---------QWVGLPYRKEISECTTEAKVLQLNAQDKD 942
+F L +F+ LF +T SE ++K SV E+ K N+ IG LE+E TY G I D++ ++ V+S +DRE A II + I + I+++D+NDN P F D + ++IPE + A D D K G Y S + + F ++ + +L V G LDRE + L A D G + C + + I D+NDN P W GLP K+ LNA D D
Sbjct: 9 IFLLNHLIFFHLFN-FTHQFSEETIKF--SVSEDAKLNTIIG---------------------HLEAEIGYTYRLSRGNSKIKFDEQTLELSVSSPLDRES---------ENAIDMLIITSPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFL--FLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLNWNGLP----------NTKLFSLNATDLD 255 HSP 6 Score: 62.3882 bits (150), Expect = 2.692e-9 Identity = 43/136 (31.62%), Postives = 67/136 (49.26%), Query Frame = 1
Query: 1474 SSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG---DYEVKETFGINH----NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSY 1860
+ + IIT+ + N + P + + E+A IG G + A+D DS + +++Y I+ DY+ GI H +G + K D E K Y F EAKD G P+ +C I + DVNDN+P+ + Y
Sbjct: 614 TQTSIITLIVKPLNQHSPI--CQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYD-----GIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRY 742 HSP 7 Score: 61.2326 bits (147), Expect = 5.419e-9 Identity = 55/192 (28.65%), Postives = 90/192 (46.88%), Query Frame = 1
Query: 1693 NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS--YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDED 2262
+G I N LD E Y F + A + + ++ I V D ND P T + K++E + IG A D D GQNG + + S +T + G I+ +DRE+ ++L++ D G P +AT+ + I V D+NDN P+F + ++ I+++ GS + + ATD+D
Sbjct: 1604 DGTIFTNSPLDFENIKTYRFNITAGKS-------TSQVIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSLFAVNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFEL----SSYFIKISENSKIGSKIIRILATDKD 1784 HSP 8 Score: 60.077 bits (144), Expect = 1.248e-8 Identity = 51/171 (29.82%), Postives = 75/171 (43.86%), Query Frame = 1
Query: 1135 TTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNN 1632
+ I L +K N H P+ ++ + + + EN + RI DED G++ S Y ++ IF L+S G FD EK Y+ E D GTP+ +++ TIFI D NDN P F + + T +IS K + IV A D+D N
Sbjct: 617 SIITLIVKPLNQHSPICQI--TEIHVLENAPIGTIFGRIQARDEDSGLSGVVS--------------YKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATIS--GKSNETVAIVQANDNDVDVKN 769 HSP 9 Score: 58.9214 bits (141), Expect = 2.512e-8 Identity = 89/347 (25.65%), Postives = 152/347 (43.80%), Query Frame = 1
Query: 1528 HFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTF-RFRVRSRSTPIDIQ-----VYNEGKIIY--FGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYP 2541
F E FS+SEDAK+ IG + A+ TY + G+ ++K ++ ++ LDRE ++ + + P++ I I VLDVNDN P + VE E + + A+D D G+NGT ++ + +D V ++G + G +DRE D + + ID G P +++ ++I +LD+NDN P F L + + + + + ATD D N + Y + T ++FSI + ++ + + + VVEARD G P LS T + + + +E ++N ++ P DYP
Sbjct: 26 QFSEETIKFSVSEDAKLNTIIGHLEAEIG-------YTYRLSRGNSKIKFD---EQTLELSVSSPLDRESENAIDMLIIT---SPPSI---IHILIDVLDVNDNSPIFPIDV--QRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF------GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDENILVTQNNTECLQRC--EFVVEARDSGVPPLSTTLNIVVNM-----EYGNEHEPNINIRFY-PSDYP 340
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 182.185 bits (461), Expect = 7.583e-46 Identity = 185/720 (25.69%), Postives = 314/720 (43.61%), Query Frame = 1
Query: 352 SVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELID----HGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIG--GQIRFKISENSQNYEM--IVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG---RSNETTIELEIKDCNDHRPVIKVH-----SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVR---SRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNP-PRTATTTVHIEVLDVNDNRPKF-----TYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARDQG 2421
++D G++ +DRE + + + Y I E++I+++D+NDN P F I E+ + L A D D + GV Y + +N F L+ G+ +L G+LDRE+ S++ ++ A DGG G ++ V I DVNDN P + Y ++E V+ + A D D +G +I + ++E + + + TE + +KS K+ + + A G + T + + + D NDH P+I + EN + +V + V D D G+N S + VS + + LE I ++N + DRE+ +Y++ V+ D GTP +++ + I ++D ND+ P FE + +SE A G + + A D D+ N + Y I+ E+K G I LDRE++D E ++ A+D G ++++I+LD ND P+ S + V E + + A+D D G NG+ F + R P+ + G++ +DREK+ + ++ V D G P P++AT TV + V DVNDN P+F Y L + + + + ++ I+ V A+D+D G N I Y L + +S + + P +L+V ARD G
Sbjct: 104 TLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYPI-------EVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNV--DNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDND----LGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRI-----VSGNELGHFRLEEAADLHIVRVNGV----LDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQRE--QNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAG 799 HSP 2 Score: 152.14 bits (383), Expect = 1.391e-36 Identity = 174/660 (26.36%), Postives = 287/660 (43.48%), Query Frame = 1
Query: 493 IEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIV--EITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQ--------TIG-----------GQIRFKIS---ENSQNYEMIV----------RIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETT-IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-----GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPN-LNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQ-NGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD 2340
I++ D NDN P F+ + IPEN R + VA+D D G + S + F L N L + LD E ++ + + A D G I V + D+NDN P + + Y E+ E +V+ ++A+D D T G G IR + + E+ Y + V + E+ L L + + +++ + +A + R + T + + IKD ND PV + ++ I EN +V + D D+G N + + D + PL QL + L DRE S Y + + D G P S+ + I I DENDN P F+ + + S++E+A IG + V A D D N I YSI+ D+ + E G+ + + K L+ E RY TV A+D N D+ ++ I +LD+NDN P + + Y +++E+ + Y+ +NA D D N R+ ++ + + + G I +DRE+ + + + +D G+PP T T V +EV D+NDN P F +A + +++ +G+ V +ATD+D GLN + +NL ++ + F I S+
Sbjct: 1910 IQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDAD---LGQNAQLSYGVVSDWANDVFSL----NPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEF--LAHQKQQRLSSTVKVTILIKDVNDEVPVF-ISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEAR--DEDMGQSDPLPFSLNPTDGQLRVVDAL--DRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGV-----VRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGG-YVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHA----TVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR--FHIDSE 2543 HSP 3 Score: 141.739 bits (356), Expect = 2.323e-33 Identity = 170/692 (24.57%), Postives = 293/692 (42.34%), Query Frame = 1
Query: 346 LISVDQKKGDIWVTSAIDREEICQPI---------SKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR---IIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRP------VIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTF----------RFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDF-GLNGSIIYNLTNQNHTKDLFSI 2331
L ++ GDI + +DRE+ + S LTG + +++E+ DINDN P F+ + EN+ + P A D+D G+ ++ + H ++ + LDRE + L A D + + + + ++DVNDN P++ Y + E ++ + V A D DD + + + IS Q+Y I + + L L KS + +IV+ A D +S + EL + RP + +S + E+ + ++T+++ T +G+ + ++ + DS+ P N G + Q GL D E Y + + D TP++ S +IT+ ++D NDN P E + E+ I +V A D DS N + Y + D++ TF I +G+I+ LDRE Y F VEA D G P++ + + + +LD NDN P+ + +S + E+ E ++ ++ +SD D+G N +FR+ +S G I G++DRE+ D+ + V D A T + I + D NDN P+F + + ++ + +A +VG++ ATD D G N I Y+L +FSI
Sbjct: 2433 LFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGI------------VRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDE---GLNAKLRFNLLGEHMHRF-----HIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGEN--AVVHYTISGRDQHYFDINTKTGVVSTKLELKTKT-KSHDDLTYTIVISAMDQGEQSLSSKAELTVI----LRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAI--AGGIMGDSLRVDP--NSGLLSVGQ----DGL--DYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFD--GTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSLNVTENAEIGS---FVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQS----------GNITVAGHLDREQQDEYILKVVASDGA---WRAETPITITIQDQNDNAPEFEHSFY-SFSFPELQQSIA---LVGQIIATDRDKQGPNSVISYSL---QQPSPMFSI 3062 HSP 4 Score: 140.584 bits (353), Expect = 4.575e-33 Identity = 176/739 (23.82%), Postives = 307/739 (41.54%), Query Frame = 1
Query: 352 SVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDG-----GGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTE---AKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNG-TPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-LDREVKDR----YEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESW---EREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG--NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
S++ G + V A+DRE L ++L I D +L I I+D NDN P F P + + + EN + + A D D G ++ +N+ I + +RV +L+ E + + + A D G+ + + + I D+NDN P ++ PY + E T VL +NA D D P + Q+R+ + E + + RI + I L + E ++V + + + +E++D ND+ PV ++ S ++EN S V TD+D+G+N++ +L G F ++S G DRE+ S Y + ++ D+ T +SS +TI +SD NDN P F++ ++ E G + A D D N ++ Y+I G + F IN + K+ L + K Y + A D GE +L+ ++ +I+ PE+ ++++ + E I K++A+ G G R+ + ++V ++ G +D E ++ ++ D P + T + + V D NDN P + NA + ++ + ++ VKA+D D G NG++IY L QN F I G+I + +LD + VVEA DQG P ++ T ++ + D
Sbjct: 2222 SLNPTDGQLRVVDALDRE---------LRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANG----RIRYSIVLGDQNHDFSISEDTGV---VRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAE--LTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTP-PLNSQVRYFLKEGDSD---LFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNL-----------------LGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISG--RDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVIL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAE----VLEEESPPQLIAVVKASDRDSGDNGNVIYRL--QNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKND 2908 HSP 5 Score: 139.813 bits (351), Expect = 8.350e-33 Identity = 182/690 (26.38%), Postives = 283/690 (41.01%), Query Frame = 1
Query: 355 VDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFE---LQIEIIDINDNFPSFQPD---EKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVI---GDLDRENIKSFEFHLYASDGGGNQGKCRIIVE--ITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGE-GRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDRE---KASRYS-------------------VEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPN-LNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS--RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQ 2304
+D + G I +DREE L + + A + + I IID+NDN P F D E TI +PEN A E L +DRD+ GV S++++ + + I P V+ + E L A+D G ++ + I DVND+TP + Y + E T + L A D D +G G+I ++I E N E + +F + L++ + ++ A V G+ RS+ + + + D ND+ P + + I EN + V ++T D D G N+E S +L+ S +T NG K + FDRE K SR + +E +DNG P + + + ++D NDN P F +ISE A G I V +D+D N + YS+ E + + GQ+ L + LDRE ++ + V AKD + L+ + I I+VLD NDN PE + S S V E + + ASD D G N F + + R I G + +D E + + + D G P + T ++ V+D NDN P F + I + + + + V A D D GLNG + Y ++ Q
Sbjct: 881 IDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDA---GVNSRISYSLTNNPNQQF--------RIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDID----LGDNGRISYEIIEG--NTERMFGVF--PDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLS-----SQTQDFTIDTRNGFIKTLRP--------FDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSE--VSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSIT-GSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAI----VRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQ 1531 HSP 6 Score: 131.339 bits (329), Expect = 3.617e-30 Identity = 135/462 (29.22%), Postives = 211/462 (45.67%), Query Frame = 1
Query: 1129 NETTIELEIKDCNDHRPVIKVHSSS---LKIKENEK--SKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-LYFDR----EKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXX----------------------XXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARD 2415
+ + + I D ND+ PV + S + + EN +I ++R V D D G+NS S SL + N Q+ F++ + G LY R E S VE++ D G+P +SS +++ I+D ND+ P F+ S+ E K+ + A D D N I+Y II + + FG+ +G + + LDRE +D Y TV +D G+P+ + + I V+D NDN P+ + S ++F I E+ + ++GKL A DRDIG+N F + S++ I N G I DRE + K+ V DNG P V + V DVNDN P+F L A ++ I++ + G+ + V D D GLNG + Y+L N + GQ+ L ++LD + + L+V A+D
Sbjct: 924 GQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSR--VRDRDAGVNSRISYSLTN---------------NPNQQ--FRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEII-EGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADT---FVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRN-GFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEF----LRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKD 1357 HSP 7 Score: 129.028 bits (323), Expect = 1.512e-29 Identity = 194/755 (25.70%), Postives = 317/755 (41.99%), Query Frame = 1
Query: 340 RHLISVDQKKGDIWVTSAIDREEICQ-----PISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYG-VXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG-------GNQGKCRIIVEITDVNDNTPQWVG-----LPYRKEISECTTEAKVLQLNAQDKDDPQ--------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG----ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKA-SRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSAT----TTLYIRYFKPR 2475
R +D G +++ +D E+I S C T + +++ + ++D NDN P F +I E + + A D DS G V K +F + N + + ++DRE+I +F + A+D + +IVE D+NDN P +V LP + S+ ++ A V+Q++A+D D G Q FK+ N+ + E L + A++S + + + I G G S + + E + K+ S + ENE I + +TVT E+ TN + S G ++F +++ G+ DRE Y VEV G +S + + + D+ND+PP F +++SED +IGH I + A D D+ + +T+ ++ ++ K + G++ LN LDRE K +YE + D + I V D NDN P T YSF I E+ +R ++ +G++ A D D+GQN + V S D+ N G + +D E+V ++V DNG P + T TV+ VLD+NDN P F ++ + N+ + V V A D D G NG I Y++T + + F I S+G I ++ LD + ++ L V ARD S + T L ++Y PR
Sbjct: 1429 RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLY--------NVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGI----NTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVE--DINDNAPVFVSMNAAILPPKFSTSKGSSTA-VMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRS--------KLSGS---VYENEP--IGTSILTVTAHLASAEIEYFV----TNVTATGS-------RGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGS--VTFLLMDGHDGKFLLEPS-TGKLILNDTLDRETKSKYELRIRVSDGVQ---YTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQ---VGQIVARDADLGQNAQLSYGVVSDWAN-DVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENV----PIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSE-FGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPR 2129 HSP 8 Score: 120.553 bits (301), Expect = 7.137e-27 Identity = 166/651 (25.50%), Postives = 271/651 (41.63%), Query Frame = 1
Query: 499 IIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYIT-------ESILYLNIGALKSFKEN--KASI--------VVIAADGEGR-SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL---NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTP-TMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQ-----VYNEGKIIY-FGNIDREXXXXXXXXXXXXXNGNPPRTATTT---VHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ 2334
I D+ND+ P F +PE ++ F A D D G I E F + G YL V LDRE + + D G +++ + D NDN PQ+ + I E + V +L A D+D IG ++ F +S +Q++ + R +I E+++ ++ A S ++ + S+ ++ +G R ++ +++ + D ND+ P + I E +T + D D+G+N + SL N+ +LDS GQ + G DRE + + V+ D +SS+ ITI + DENDN P F S+ E + G E+ A D+D N+ + +SI ++TF I+ G ++L+K LD E Y + A D G P+L+ + ++V+D NDN P ST+ +I E + I + A D D G NG + + S+ P Q + E +I+ IDRE +D + V D P +T V + V D+NDN P F +NA + + + V +V A D D NG + Y + + ++LF +Q
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDID---LGDNGRISYEIIEGNTERMFGVFPDG-----YLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRD----IGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSAT-------GQLSL-------GRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNR-RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTP---IVTVTADDPDSGLNGKVSYAI-SKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVS--MNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIV--SGPQELFKLQ 1654 HSP 9 Score: 117.472 bits (293), Expect = 5.757e-26 Identity = 158/625 (25.28%), Postives = 257/625 (41.12%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPEN-VARSSEFSLPV-AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG---EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS--EFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFK-----TFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG-----DYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLT 2298
EL I I+DINDN P+F ++ EN V + + L V A D D+ ++ + F + +I ++ LDRE + L A D G G + VE+ D+NDN P + Y + E + VL A DKD + + ++RF + E + R +E+ L + + + ++A D E R++ + + + D ND+ P + ++ + E V D D G N+ ++ S D ++ +++ + G +L + + D Y++ + D G ++SS +T+ + PP F F++SED + G I V A I Y+I G V G+ GQ LD E+ YE +EA D P+L I + V D NDN P + E E E I + ASDRD G NG +R+++ ++ G+I +DRE++ +V+ +D G P T T +V + +LD NDN PKFT LN+T++ GS V V ++D D G N + Y+ +
Sbjct: 2369 ELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPL---NSQVRYFLKEGDSDLFRINASSGDI----ALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKD--EGLNAKLRFNLLG-----EHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINT------KTGVVSTKLELKTKTKSHDDLT----YTIVISAMDQGEQSLSSKAELTVIL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQ----DGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQL--IYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGT-FEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLF-----SLNVTENAEIGSFVIRVTSSDLDLGANANASYSFS 2952 HSP 10 Score: 115.161 bits (287), Expect = 2.868e-25 Identity = 169/715 (23.64%), Postives = 302/715 (42.24%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISEC-TTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRII--VLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDI-GQNGTFRFRV----RSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGS-IIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNN 2577
+ I I+D ++N P F+ E +P++ R A D+ + G + ++ ++ + F + H + ++ ++ + +E + A+D G + R+++ +T N +TP++ Y+ + E + +L + A D D G +R+ IS ++ + V T I+ +E +I V S+ + + + D ND+ PV I EN+ V + D+D N+ + L +G + F +N G + FD E+ Y++++ N +M S + + + N+ P F F +SE + +G +G V A D DS + + Y ++G K F I+ N G I++ + LDRE ++R TV AK+ G ND+ + ++I + D ND I Y+ I E+ K + + A D+D+ QN F + + +S ID+Q G+I +DRE+ ++++ ID G PP+T + TVHIE+ DVNDN P FT LN + I+++ AG+ + + A+D D NG Y L H K S+ + ++ + P ++E D G P + L I D+ + + N D P V ++ PN+
Sbjct: 3110 VNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDK--QDLGTNEMDYSLMTFNL-SSIFSVGRH----DGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPN--GMLRYSISGGNERQDFSVD--ERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAF---------------LPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAK-NPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDK-GFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFIKHYYTSTISEAAPVGTK---VTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQT---GEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGY----ISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKH-KSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFN-GDLPSNVKLADVRPND 3784 HSP 11 Score: 111.694 bits (278), Expect = 2.903e-24 Identity = 200/803 (24.91%), Postives = 333/803 (41.47%), Query Frame = 1
Query: 307 QLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQ---------IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--------------------------------GNQGKCR------IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEM-----IVRIFYITESILYLNIGALKSFKENKASIVV-IAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS--EFSCSLNDTNF---VSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGT--PTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKI--GHEIGIVIAKDSDSSP-NNIITYSII-GDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRST---PIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNG-NPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRL----VVEARDQGTPSLSATTTLYIRYFKPRDSF 2484
QL + + + S++ + G + +T+ +D EE+ +YI+ Q + ++D+NDN P F P + ++ ENV ++E AKD DS G+ +Y + + + G + N +R +LDRE+ ++ + A D +Q + R + + I DVND P ++ + V+ + A D D+ + G I + + E +++ +M + T+ L + + AL +E ++S ++ I A G +S E+ + + I D ND+ PV S + EN +V +++ TD D+G N +S L D N +S D+ +N + E+ SRYS+ V D P ++E +TI I D NDN P F + E+ G + V A D+D+ P N+ + Y + GD ++ F IN +G I L K LDRE + Y T+ A D G P L + +R+ V D+NDN P V H + A+D+D G N RF + ID + G+I +DRE+ + + D+ PR ++ + I V DVNDN PKF N + + + ++ G V +A D D G N + Y ++ ++ + F I + G + K +L TK K+ D L V+ A DQG SLS+ L + +P + F
Sbjct: 1956 QLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEV------------QHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDS--------EFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRN--GYIDYLMKE-ARDEDMGQSDPLPFSLNPTDGQLRV-VDALD--RELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKN----------------LNYERLSRYSLTVRAEDCALENPAGDTAE-LTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDL---FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPR--ATDKDEGLNAKLRFNLLGEHMHRFHIDSET---GEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYN----VAVPERISKGEFVFGARALDLDDGENAVVHYTISGRD--QHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELF 2700 HSP 12 Score: 110.153 bits (274), Expect = 9.236e-24 Identity = 171/745 (22.95%), Postives = 308/745 (41.34%), Query Frame = 1
Query: 139 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQ------IEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSE-KYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTE-AKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEM--IVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTD-EDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHF--YIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTK 2316
+ QL + V++ E +L V+ + + + GN+I +QN T F++ + G+I+ +DREEI G + + D + + + ++D NDN P F T NV ++E V + S+ G S S + E + GN + V G LDRE + + ASDG + + I + I D NDN P++ Y E A V Q+ A D+D Q I + + + S + + + +++ + + ++S EN ++ V+A D G+ +E + + I D +++ P + + ++ + R+ D +D G N E SL N L S+++ +G + + P +RY + V D G P S + I ++ EN + P F + E+ +G I V A D D+ PN ++ YSI G E ++ F ++ G I + + LD ++ Y + +D G L+ + II+ DVNDN P ++ K + E+K ++ + +A+D+D +N + + N+ G I + D E +I L N + + +++ VL VN+ P+F P+ + ++++ A G+ VG V+ATD+D G +G + Y L ++ K
Sbjct: 2809 VMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGT-------FEI----------------TESGEIYTRMRLDREEI---------GDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-----TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGN-----ITVAGHLDREQQDEYILKVVASDGAW-RAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDK-QGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRS-PENMYALTVLATD-NGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTN-EMDYSLMTFN---LSSIFSVGRHDGWITLVKPIQVPPN--------TRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNE-RQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPP----VFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYE-ERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVF----HFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDK 3485 HSP 13 Score: 108.997 bits (271), Expect = 1.910e-23 Identity = 159/657 (24.20%), Postives = 280/657 (42.62%), Query Frame = 1
Query: 487 LQIEIIDINDNFP----SFQPDE-KTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITE-SILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPT-MSSSEIITIFISDENDNPPHFETEFKTFSISEDA---KIGHEIGI------VIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHL--NKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV---LDVNDNIPEISTSYSFKIVESWEREH-----KHFYI-------GKLNAS-DRDIGQNGTFR-FRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRT------ATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN 2301
+ + ++D ND+ P F PD K + EN + + KD DS G+ I S +F L + +++ +RV G LDRE I + + A D G +I+++ DVND+ P + Y +SE T + V + A D+D + Q+ + I ++ ++ F + + L + G L + + + A DG + T +++ I D ND P ++ + E+ + +V +T TD DQG N + +L S++ +Y PL+ F L+++ G DREK S+Y + VI D G PT S++ + + ++D NDN P F +S+++D K+ E+ V A D D N +I Y + E F ++ +G I L + K Y+ V A+D G+ + I++ L++ + + Y F++VE E++ + I GK N+ + DI Q + FR+ +RS G+I +DRE+ + + + + V+I ++D+NDN P F + +++ ++ A G + + D D G+N I Y+LTN
Sbjct: 368 VTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDS---GLNGRTSVRIVSGNELGHFRL-EEAADLH-IVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDED--TGVNAQVHYDILSGNE-----LKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAP----SVERLY--PLQ-------FALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGE--GLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRS----------GRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDR-ESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTN 986 HSP 14 Score: 99.3673 bits (246), Expect = 1.624e-20 Identity = 173/775 (22.32%), Postives = 315/775 (40.65%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISK---------CLTGAFL-NYIIF----ADHQIFELQ------IEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ---GKCRIIVEITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIGGQIRFKISENSQ----NYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTI--ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPT---MSSSEIITIFISDENDNPPHFETEFKT-----FSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVL----------------------DVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXN-GNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLF 2325
S+ EN ++ +G L + ++ ++ E+ SF L S+ + ++D + G I DRE + + +S+ L G+ NY++ +D+ I LQ + + D+NDN P F + I E + + + +D D G+ S++ F L ++ L + LDRE+ + + A D I + + D NDN P++ + E + T ++++ A D D Q + Q+ F IS ++ + + I Y+ + + Y +I S+ N + A+D S TT+ + + D ND+ P+ + +IKE K + +T D D G+N + S ++ S L G + F +N+ G+ DRE + + V+ D P+ +S+ +++T+ + D NDN P F + FS S+ + + V AKD+DSS N ++TY I+ +E F + N G I + + RY+ T+++ D + S ++ I ++ V +N P I TS + +++ + A+ G G R ID ++ G + +DRE + + G PRT+ T V + VLD ND+ P+F L+ N+++D+ G + ++A D D GS+ + L + + K L
Sbjct: 1160 FSIPENAPADTFVGKLTAVDRDIGRNAEL----SFTLSSQTQD------FTIDTRNGFIKTLRPFDREALVK-VSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADE---GLNGDVYYSLAKGNEAGQFNL----DSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDAD--QGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDI---TSYTLN-----ITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAI---------SKQEPQLPQG---RHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTA--VMQVHAKDADSSSNGLVTYEIVSG--PQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEP-IGTSI-LTVTAHLASAEIEYFVTNVTAT----GSRGQV-----DRLFDIDAKL---GILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQF----LDTPFVYNVSEDLQIGHTISTLRAHDPD--TLGSVTFLLMDGHDGKFLL 1870
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 178.333 bits (451), Expect = 1.277e-44 Identity = 168/624 (26.92%), Postives = 287/624 (45.99%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV--RIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENG-GQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI----IGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+Q++++D NDN+P F T+++PE+ +E + VA R ++ G +I ++ F + +++ ++ LD E+++S+ + A DGG +++V + D NDN P++ +++ + E ++++ A D D + +I + ISE N+ + V R ++ I L ++ + + V+A DG +S +++ + ++D ND+ P + E++ VT +T TD D+ + + +T + +NG G I Q D ++ R+ + V D+G S + + I I+D N+ P FE + S+ EDA +G + +V A DSD N ITYS+ I + F IN G I N LDRE Y TV AKD G P+L+D+ + I V DVNDN P S Y I+E +G ++ ASD D+G NG ++ + R V + G I +DRE V + +D G+PP ++T V I + DVND+ P F + L + ++ GS+VGE+ A D D G+N + Y++
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNT-VAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVS----LVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD--EGANAEITYSISERDDNFPLAVDPRTGWVQ------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTR-----GRFAITSQNGRGLITIAQ-------SLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED-------ALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKIT----LYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSI 1152 HSP 2 Score: 174.481 bits (441), Expect = 1.963e-43 Identity = 211/797 (26.47%), Postives = 334/797 (41.91%), Query Frame = 1
Query: 184 FSVKLYL-SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-----YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR-----IIVEITDVNDNTPQWVGLPYRKEISE----CTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN---NIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRST-------PIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
F LY+ SV E Q P G + ++ + + L +S + L VD + G + ++++DRE L ++ D LQ+ ++D ND+ P+F+ ++ I E S A D+D K YG++ + + E ID + + + LDRE S+ + A+D Q + R + V++ D NDN PQ+ Y ++ E T + V + A D D Q IR+ I N+Q+ I + + L+ +++S++ +V+ A DG RSN T + + + D ND+ P + EN + R+ D D+G N+E +S S D NF + P G + I L DRE+ R++ +V+ D G P S+S + I + D NDN P F ++ ++ ED G + V A D D I T + G + + N G I + + LD + + R+ TV A D+G +D+ + I + D N+ P + YS + E + +A+D D+G N + + S P I G I+ +DRE + V D GNP + TT V I V DVNDN P F PL A +I +D G+ V +V A+D D GLNG I Y L++++ F I + G I K LD + L A D+G+P LS+T + IR
Sbjct: 359 FEQALYVASVLEEQ----PAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQS----LFKVDSRTGVVTTSASLDRE---------LMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDAD--QGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYR-----LVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF----PLAVDP-RTGWVQTIKPL--------DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQ---NGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVV---SATDSDVGVNAQITYSLNEESINGLGSPDPFSINP-QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQA----SILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIR 1102 HSP 3 Score: 127.487 bits (319), Expect = 5.179e-29 Identity = 136/563 (24.16%), Postives = 229/563 (40.67%), Query Frame = 1
Query: 349 ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK---YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNG----QIHLNKILDRE-VKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREH-KHFYIGKLNASDRDIGQNGTFRF 1965
++VD + G + +DREE G F ++ D + + I + D+NDN P+F P + E+ + + A D D + Y + + + +N LI + LD + K F + A+D GG + + ITD N+ P + PY + E VL ++A D D + QI + ++E S N F I + A + ++ + A G S+ T +E+ + D ND+ P K I E+ V ++ +D D G+N L+D + +E+G F ++ G DRE + + + I D G+P +SS+ + I + D ND+PP F ++ T + E++ +G +G + A D D N ++ YSIIG + + G Q+ LD E + R+E V A P L + I I+V DVNDN P + F+++ + R+H IG++ A D D+ +R
Sbjct: 737 LAVDPRTGWVQTIKPLDREE---------QGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLIT----------IAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD--VGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD-----------IEDGS----FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRI 1257 HSP 4 Score: 97.8265 bits (242), Expect = 4.916e-20 Identity = 104/344 (30.23%), Postives = 163/344 (47.38%), Query Frame = 1
Query: 1525 PHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHF--YIGKLNASDRDIGQNGTFRFRVRS----------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPP---RTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
P+FE S+ E+ G + V A+D + SP + YS++ D + F ++ G + + LDRE+ D + F V A D+ P + + +++ VLD ND+ P ++ + E+ RE + L A+D+DIG+N + + + + PI G I ++DRE D +LV D + RTAT +V ++VLD NDN P+F TY + + T+D + V ++ATD D G N +I Y + N T+ FSI S G + L K LD + RLV+ A+D G+PS S TT L + D+ R
Sbjct: 357 PYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSP----TFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTED----NTVAHIRATDADQGNNAAIRYAIIGGN-TQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPR 688
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0300578) HSP 1 Score: 178.333 bits (451), Expect = 1.277e-44 Identity = 168/624 (26.92%), Postives = 287/624 (45.99%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV--RIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENG-GQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI----IGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+Q++++D NDN+P F T+++PE+ +E + VA R ++ G +I ++ F + +++ ++ LD E+++S+ + A DGG +++V + D NDN P++ +++ + E ++++ A D D + +I + ISE N+ + V R ++ I L ++ + + V+A DG +S +++ + ++D ND+ P + E++ VT +T TD D+ + + +T + +NG G I Q D ++ R+ + V D+G S + + I I+D N+ P FE + S+ EDA +G + +V A DSD N ITYS+ I + F IN G I N LDRE Y TV AKD G P+L+D+ + I V DVNDN P S Y I+E +G ++ ASD D+G NG ++ + R V + G I +DRE V + +D G+PP ++T V I + DVND+ P F + L + ++ GS+VGE+ A D D G+N + Y++
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNT-VAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVS----LVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD--EGANAEITYSISERDDNFPLAVDPRTGWVQ------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTR-----GRFAITSQNGRGLITIAQ-------SLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED-------ALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKIT----LYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSI 1152 HSP 2 Score: 174.481 bits (441), Expect = 1.963e-43 Identity = 211/797 (26.47%), Postives = 334/797 (41.91%), Query Frame = 1
Query: 184 FSVKLYL-SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-----YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR-----IIVEITDVNDNTPQWVGLPYRKEISE----CTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN---NIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRST-------PIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
F LY+ SV E Q P G + ++ + + L +S + L VD + G + ++++DRE L ++ D LQ+ ++D ND+ P+F+ ++ I E S A D+D K YG++ + + E ID + + + LDRE S+ + A+D Q + R + V++ D NDN PQ+ Y ++ E T + V + A D D Q IR+ I N+Q+ I + + L+ +++S++ +V+ A DG RSN T + + + D ND+ P + EN + R+ D D+G N+E +S S D NF + P G + I L DRE+ R++ +V+ D G P S+S + I + D NDN P F ++ ++ ED G + V A D D I T + G + + N G I + + LD + + R+ TV A D+G +D+ + I + D N+ P + YS + E + +A+D D+G N + + S P I G I+ +DRE + V D GNP + TT V I V DVNDN P F PL A +I +D G+ V +V A+D D GLNG I Y L++++ F I + G I K LD + L A D+G+P LS+T + IR
Sbjct: 359 FEQALYVASVLEEQ----PAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQS----LFKVDSRTGVVTTSASLDRE---------LMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDAD--QGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYR-----LVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF----PLAVDP-RTGWVQTIKPL--------DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQ---NGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVV---SATDSDVGVNAQITYSLNEESINGLGSPDPFSINP-QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQA----SILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIR 1102 HSP 3 Score: 127.487 bits (319), Expect = 5.179e-29 Identity = 136/563 (24.16%), Postives = 229/563 (40.67%), Query Frame = 1
Query: 349 ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK---YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNG----QIHLNKILDRE-VKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREH-KHFYIGKLNASDRDIGQNGTFRF 1965
++VD + G + +DREE G F ++ D + + I + D+NDN P+F P + E+ + + A D D + Y + + + +N LI + LD + K F + A+D GG + + ITD N+ P + PY + E VL ++A D D + QI + ++E S N F I + A + ++ + A G S+ T +E+ + D ND+ P K I E+ V ++ +D D G+N L+D + +E+G F ++ G DRE + + + I D G+P +SS+ + I + D ND+PP F ++ T + E++ +G +G + A D D N ++ YSIIG + + G Q+ LD E + R+E V A P L + I I+V DVNDN P + F+++ + R+H IG++ A D D+ +R
Sbjct: 737 LAVDPRTGWVQTIKPLDREE---------QGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLIT----------IAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD--VGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD-----------IEDGS----FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRI 1257 HSP 4 Score: 97.8265 bits (242), Expect = 4.916e-20 Identity = 104/344 (30.23%), Postives = 163/344 (47.38%), Query Frame = 1
Query: 1525 PHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHF--YIGKLNASDRDIGQNGTFRFRVRS----------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPP---RTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
P+FE S+ E+ G + V A+D + SP + YS++ D + F ++ G + + LDRE+ D + F V A D+ P + + +++ VLD ND+ P ++ + E+ RE + L A+D+DIG+N + + + + PI G I ++DRE D +LV D + RTAT +V ++VLD NDN P+F TY + + T+D + V ++ATD D G N +I Y + N T+ FSI S G + L K LD + RLV+ A+D G+PS S TT L + D+ R
Sbjct: 357 PYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSP----TFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTED----NTVAHIRATDADQGNNAAIRYAIIGGN-TQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPR 688
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304900) HSP 1 Score: 178.333 bits (451), Expect = 1.333e-44 Identity = 168/624 (26.92%), Postives = 287/624 (45.99%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV--RIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENG-GQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI----IGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+Q++++D NDN+P F T+++PE+ +E + VA R ++ G +I ++ F + +++ ++ LD E+++S+ + A DGG +++V + D NDN P++ +++ + E ++++ A D D + +I + ISE N+ + V R ++ I L ++ + + V+A DG +S +++ + ++D ND+ P + E++ VT +T TD D+ + + +T + +NG G I Q D ++ R+ + V D+G S + + I I+D N+ P FE + S+ EDA +G + +V A DSD N ITYS+ I + F IN G I N LDRE Y TV AKD G P+L+D+ + I V DVNDN P S Y I+E +G ++ ASD D+G NG ++ + R V + G I +DRE V + +D G+PP ++T V I + DVND+ P F + L + ++ GS+VGE+ A D D G+N + Y++
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNT-VAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVS----LVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD--EGANAEITYSISERDDNFPLAVDPRTGWVQ------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTR-----GRFAITSQNGRGLITIAQ-------SLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED-------ALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKIT----LYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSI 1152 HSP 2 Score: 174.096 bits (440), Expect = 2.194e-43 Identity = 211/797 (26.47%), Postives = 334/797 (41.91%), Query Frame = 1
Query: 184 FSVKLYL-SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-----YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR-----IIVEITDVNDNTPQWVGLPYRKEISE----CTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN---NIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRST-------PIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
F LY+ SV E Q P G + ++ + + L +S + L VD + G + ++++DRE L ++ D LQ+ ++D ND+ P+F+ ++ I E S A D+D K YG++ + + E ID + + + LDRE S+ + A+D Q + R + V++ D NDN PQ+ Y ++ E T + V + A D D Q IR+ I N+Q+ I + + L+ +++S++ +V+ A DG RSN T + + + D ND+ P + EN + R+ D D+G N+E +S S D NF + P G + I L DRE+ R++ +V+ D G P S+S + I + D NDN P F ++ ++ ED G + V A D D I T + G + + N G I + + LD + + R+ TV A D+G +D+ + I + D N+ P + YS + E + +A+D D+G N + + S P I G I+ +DRE + V D GNP + TT V I V DVNDN P F PL A +I +D G+ V +V A+D D GLNG I Y L++++ F I + G I K LD + L A D+G+P LS+T + IR
Sbjct: 359 FEQALYVASVLEEQ----PAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQS----LFKVDSRTGVVTTSASLDRE---------LMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDAD--QGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYR-----LVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF----PLAVDP-RTGWVQTIKPL--------DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQ---NGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVV---SATDSDVGVNAQITYSLNEESINGLGSPDPFSINP-QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQA----SILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIR 1102 HSP 3 Score: 127.102 bits (318), Expect = 5.881e-29 Identity = 136/563 (24.16%), Postives = 229/563 (40.67%), Query Frame = 1
Query: 349 ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK---YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNG----QIHLNKILDRE-VKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREH-KHFYIGKLNASDRDIGQNGTFRF 1965
++VD + G + +DREE G F ++ D + + I + D+NDN P+F P + E+ + + A D D + Y + + + +N LI + LD + K F + A+D GG + + ITD N+ P + PY + E VL ++A D D + QI + ++E S N F I + A + ++ + A G S+ T +E+ + D ND+ P K I E+ V ++ +D D G+N L+D + +E+G F ++ G DRE + + + I D G+P +SS+ + I + D ND+PP F ++ T + E++ +G +G + A D D N ++ YSIIG + + G Q+ LD E + R+E V A P L + I I+V DVNDN P + F+++ + R+H IG++ A D D+ +R
Sbjct: 737 LAVDPRTGWVQTIKPLDREE---------QGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLIT----------IAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD--VGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD-----------IEDGS----FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRI 1257 HSP 4 Score: 97.8265 bits (242), Expect = 5.172e-20 Identity = 104/344 (30.23%), Postives = 163/344 (47.38%), Query Frame = 1
Query: 1525 PHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHF--YIGKLNASDRDIGQNGTFRFRVRS----------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPP---RTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
P+FE S+ E+ G + V A+D + SP + YS++ D + F ++ G + + LDRE+ D + F V A D+ P + + +++ VLD ND+ P ++ + E+ RE + L A+D+DIG+N + + + + PI G I ++DRE D +LV D + RTAT +V ++VLD NDN P+F TY + + T+D + V ++ATD D G N +I Y + N T+ FSI S G + L K LD + RLV+ A+D G+PS S TT L + D+ R
Sbjct: 357 PYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSP----TFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTED----NTVAHIRATDADQGNNAAIRYAIIGGN-TQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPR 688
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0339463) HSP 1 Score: 177.948 bits (450), Expect = 1.612e-44 Identity = 168/624 (26.92%), Postives = 287/624 (45.99%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV--RIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENG-GQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI----IGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+Q++++D NDN+P F T+++PE+ +E + VA R ++ G +I ++ F + +++ ++ LD E+++S+ + A DGG +++V + D NDN P++ +++ + E ++++ A D D + +I + ISE N+ + V R ++ I L ++ + + V+A DG +S +++ + ++D ND+ P + E++ VT +T TD D+ + + +T + +NG G I Q D ++ R+ + V D+G S + + I I+D N+ P FE + S+ EDA +G + +V A DSD N ITYS+ I + F IN G I N LDRE Y TV AKD G P+L+D+ + I V DVNDN P S Y I+E +G ++ ASD D+G NG ++ + R V + G I +DRE V + +D G+PP ++T V I + DVND+ P F + L + ++ GS+VGE+ A D D G+N + Y++
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNT-VAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVS----LVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD--EGANAEITYSISERDDNFPLAVDPRTGWVQ------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTR-----GRFAITSQNGRGLITIAQ-------SLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED-------ALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKIT----LYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSI 1152 HSP 2 Score: 173.711 bits (439), Expect = 3.040e-43 Identity = 211/797 (26.47%), Postives = 334/797 (41.91%), Query Frame = 1
Query: 184 FSVKLYL-SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK-----YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR-----IIVEITDVNDNTPQWVGLPYRKEISE----CTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN---NIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRST-------PIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
F LY+ SV E Q P G + ++ + + L +S + L VD + G + ++++DRE L ++ D LQ+ ++D ND+ P+F+ ++ I E S A D+D K YG++ + + E ID + + + LDRE S+ + A+D Q + R + V++ D NDN PQ+ Y ++ E T + V + A D D Q IR+ I N+Q+ I + + L+ +++S++ +V+ A DG RSN T + + + D ND+ P + EN + R+ D D+G N+E +S S D NF + P G + I L DRE+ R++ +V+ D G P S+S + I + D NDN P F ++ ++ ED G + V A D D I T + G + + N G I + + LD + + R+ TV A D+G +D+ + I + D N+ P + YS + E + +A+D D+G N + + S P I G I+ +DRE + V D GNP + TT V I V DVNDN P F PL A +I +D G+ V +V A+D D GLNG I Y L++++ F I + G I K LD + L A D+G+P LS+T + IR
Sbjct: 359 FEQALYVASVLEEQ----PAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQS----LFKVDSRTGVVTTSASLDRE---------LMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDAD--QGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYR-----LVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF----PLAVDP-RTGWVQTIKPL--------DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQ---NGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVV---SATDSDVGVNAQITYSLNEESINGLGSPDPFSINP-QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQA----SILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIR 1102 HSP 3 Score: 126.716 bits (317), Expect = 7.094e-29 Identity = 136/563 (24.16%), Postives = 229/563 (40.67%), Query Frame = 1
Query: 349 ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEK---YGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNG----QIHLNKILDRE-VKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREH-KHFYIGKLNASDRDIGQNGTFRF 1965
++VD + G + +DREE G F ++ D + + I + D+NDN P+F P + E+ + + A D D + Y + + + +N LI + LD + K F + A+D GG + + ITD N+ P + PY + E VL ++A D D + QI + ++E S N F I + A + ++ + A G S+ T +E+ + D ND+ P K I E+ V ++ +D D G+N L+D + +E+G F ++ G DRE + + + I D G+P +SS+ + I + D ND+PP F ++ T + E++ +G +G + A D D N ++ YSIIG + + G Q+ LD E + R+E V A P L + I I+V DVNDN P + F+++ + R+H IG++ A D D+ +R
Sbjct: 737 LAVDPRTGWVQTIKPLDREE---------QGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLIT----------IAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD--VGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD-----------IEDGS----FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRI 1257 HSP 4 Score: 97.4413 bits (241), Expect = 5.827e-20 Identity = 104/344 (30.23%), Postives = 163/344 (47.38%), Query Frame = 1
Query: 1525 PHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHF--YIGKLNASDRDIGQNGTFRFRVRS----------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPP---RTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
P+FE S+ E+ G + V A+D + SP + YS++ D + F ++ G + + LDRE+ D + F V A D+ P + + +++ VLD ND+ P ++ + E+ RE + L A+D+DIG+N + + + + PI G I ++DRE D +LV D + RTAT +V ++VLD NDN P+F TY + + T+D + V ++ATD D G N +I Y + N T+ FSI S G + L K LD + RLV+ A+D G+PS S TT L + D+ R
Sbjct: 357 PYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSP----TFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTED----NTVAHIRATDADQGNNAAIRYAIIGGN-TQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPR 688
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 267.7 bits (683), Expect = 3.662e-74 Identity = 236/768 (30.73%), Postives = 374/768 (48.70%), Query Frame = 1
Query: 241 GNLIKLIQNQTKSTEILKTKSFQLESEKSNTY----GRHLISVDQKKGDIWVTS-AIDREEI--CQPISK-CLTGAFLNYIIFADHQ---IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G L ++ + Q ST I + Q + + Y G + VD K GDI+ T IDRE + C+ K C ++ +Q + E +IE+ DINDN P F T+ +PEN + FS+P+A D+D+E+ GV Y L + ++ ++ + P L V+G LDRE S++ + A DGG + V I D NDN P++ Y E++E + VLQ+ A D D +G G+I + + + ++RI + I+Y+ G L + N V+A D +S++T + +++ D ND+ P +++ HS + I E+ V + V+D+D+G N+ +C + L S ++N ++K F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN P F +E+ + G ++ V+A D+DS N + YSII D + F I+ N G++ LDRE KDRYEF V A D G P+ + + I VLD NDN P+ S YSF ++E+ +G + D D G+N + V IQ G I+ + DREK + +D G+PPR++ V I VLD NDN P T P + +++ ++ A S+V V+A D D G N ++Y++ N DLF I S+G+I L K+L K RLV++ D+G PS A ++I
Sbjct: 24 GILYRVHEEQPPSTLIGSLAADQGLPDTGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSD----LGPNGEIEYTLHQAIDPVPKLLRIDR-SSGIIYVK-GPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDN--KRKYFLQTTTP---LDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVQDMDEGENAQVQLSVEPDVGKFVIQ-NGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKP--SNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN-PHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHI 773 HSP 2 Score: 88.1965 bits (217), Expect = 4.565e-17 Identity = 136/589 (23.09%), Postives = 231/589 (39.22%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFE------LQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL-------IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI----------GALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLND--TNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKT--FSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS 1851
S E NSPIG+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI Y++ D + I++ D NDN P+ + + I E++ + +L D+D + V + F+L +D N +L+ LD E ++ + + A D G + V++TD NDN+P + + E +E KV+++ A D D + N E++ I + + I L +++ V AAD S+ T + IK D ND+ P + S + EN V +TV D D+G N++ S+ FV ++NG + ++ FDREK S Y+ + D G P SS +TI + DENDN P + +S A + +V A+D DS N + YSI G + NG+I L K L R+ + ++ D G+P+ + I ++ + VN+ I +S
Sbjct: 247 SYEAEVAENSPIGH--SVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEINN---------LKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPASDSSVD--NKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDAD---------------SGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVGKFV---------IQNGTGTILSSIS------FDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRH---AIALVHIYVNETIANVS 783 HSP 3 Score: 62.003 bits (149), Expect = 4.412e-9 Identity = 92/405 (22.72%), Postives = 169/405 (41.73%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVI--KVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE----IGIVIAKDSD----SSPNNIITYSIIG 1656
L++++ D NDN P F P ++ E + VA D DS + I+ S FE+ + + R LDRE+ +EF + A+D G ++G +++++ D NDN P+++ Y + E + V + QD D+ + Q++ + + + + I SI + KE+ + + A DG RS+ + + + D ND+ PV+ +SS +++ +V + D D G N+E S+ N D Y SP NG +L R+ + + + + +D G P+ + ++ I++++ N H E A +GH + + IA D D + +NI+ S+ G
Sbjct: 455 LKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNA--ELVYSIIADSSTRGLFEIDPNSGEV----RARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGEN--AQVQLSVEPDVGKFVIQNGTGTILSSI------SFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN--PHDLFYISP-SNGEITLTKELT--------RKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANVSHVE-----------ALVGHSLYTPLDMDIAGDPDYGLAAQRSNIVYGSLAG 823
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 267.7 bits (683), Expect = 2.185e-73 Identity = 236/771 (30.61%), Postives = 374/771 (48.51%), Query Frame = 1
Query: 241 GNLIKLIQNQTKSTEILKTKSFQLESEKSNTY----GRHLISVDQKKGDIWVTS-AIDREEI--CQPISKCLTGAFLNYIIFA-------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G L ++ + Q ST I + Q + + Y G + VD K GDI+ T IDRE + C+ K FL + + ++ E +IE+ DINDN P F T+ +PEN + FS+P+A D+D+E+ GV Y L + ++ ++ + P L V+G LDRE S++ + A DGG + V I D NDN P++ Y E++E + VLQ+ A D D +G G+I + + + ++RI + I+Y+ G L + N V+A D +S++T + +++ D ND+ P +++ HS + I E+ V + V+D+D+G N+ +C + L S ++N ++K F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN P F +E+ + G ++ V+A D+DS N + YSII D + F I+ N G++ LDRE KDRYEF V A D G P+ + + I VLD NDN P+ S YSF ++E+ +G + D D G+N + V IQ G I+ + DREK + +D G+PPR++ V I VLD NDN P T P + +++ ++ A S+V V+A D D G N ++Y++ N DLF I S+G+I L K+L K RLV++ D+G PS A ++I
Sbjct: 24 GILYRVHEEQPPSTLIGSLAADQGLPDTGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKP---CFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSD----LGPNGEIEYTLHQAIDPVPKLLRIDR-SSGIIYVK-GPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDN--KRKYFLQTTTP---LDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVQDMDEGENAQVQLSVEPDVGKFVIQ-NGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKP--SNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN-PHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHI 773 HSP 2 Score: 88.1965 bits (217), Expect = 5.032e-17 Identity = 136/589 (23.09%), Postives = 231/589 (39.22%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFE------LQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL-------IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI----------GALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLND--TNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKT--FSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS 1851
S E NSPIG+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI Y++ D + I++ D NDN P+ + + I E++ + +L D+D + V + F+L +D N +L+ LD E ++ + + A D G + V++TD NDN+P + + E +E KV+++ A D D + N E++ I + + I L +++ V AAD S+ T + IK D ND+ P + S + EN V +TV D D+G N++ S+ FV ++NG + ++ FDREK S Y+ + D G P SS +TI + DENDN P + +S A + +V A+D DS N + YSI G + NG+I L K L R+ + ++ D G+P+ + I ++ + VN+ I +S
Sbjct: 247 SYEAEVAENSPIGH--SVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEINN---------LKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPASDSSVD--NKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDAD---------------SGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVGKFV---------IQNGTGTILSSIS------FDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRH---AIALVHIYVNETIANVS 783 HSP 3 Score: 60.8474 bits (146), Expect = 9.022e-9 Identity = 92/405 (22.72%), Postives = 169/405 (41.73%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSS--LKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE----IGIVIAKDSD----SSPNNIITYSIIG 1656
L++++ D NDN P F P ++ E + VA D DS + I+ S FE+ + + R LDRE+ +EF + A+D G ++G +++++ D NDN P+++ Y + E + V + QD D+ + Q++ + + + + I SI + KE+ + + A DG RS+ + + + D ND+ PV+ S+S +++ +V + D D G N+E S+ N D Y SP NG +L R+ + + + + +D G P+ + ++ I++++ N H E A +GH + + IA D D + +NI+ S+ G
Sbjct: 455 LKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNA--ELVYSIIADSSTRGLFEIDPNSGEV----RARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGEN--AQVQLSVEPDVGKFVIQNGTGTILSSI------SFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN--PHDLFYISP-SNGEITLTKELT--------RKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANVSHVE-----------ALVGHSLYTPLDMDIAGDPDYGLAAQRSNIVYGSLAG 823
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 254.603 bits (649), Expect = 1.610e-69 Identity = 233/805 (28.94%), Postives = 372/805 (46.21%), Query Frame = 1
Query: 133 FKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ------PISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR------IFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--------LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQ--VYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ M + L + + LY V E Q PN+ IG+L S + L + E Y R VD K GDI+ T ++IDRE + C+ P + + + ++ E +IEI+D NDN P F T+ IPEN + F++PVA DRDS G+ Y L + + ++ + P L V+G+LDRE S++ ++ DGG Q + + ITD NDN P++ Y E+ E + VLQ+ A D D G++ + + + S ++ I ++ S+ I LK + + K + + +S++ + + +KD ND+ P I++ L E+ + I V + V+D D+G N+ +C + L S S N ++K F + D E+ Y +E++ D+G P +SS+ + + ++D NDN P F E+ + G ++ V+A D+DS N +TYSI G + F IN N G++ + LDRE D Y+F V A D G P+L + + + VLD NDN P+ + YSF + E+ +G + +D D G+N + V + IQ Y I F DREK + +D G+PPR++ + I VLD NDN P T P +++ +L+ + + V V+A D D GLN + +N+ N LF I S+G+I L K+ K RLVV+ +D+GTP T ++I
Sbjct: 34 YAMLVWILLLLCCSANVVNTILY-QVTEEQPPNTLIGSL--------ASDQGLPDTGHLYKLEVGAPYLR----VDGKTGDIYTTENSIDRESLKDCRNLFEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSD--MGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDN------GPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRS--ASETGNDRKRKYFLQTTT---LLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSP---VGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISF---DREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLD--PRTSPETHVESVEAEDIDIGLNSELDFNIVGGN-PHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHI 803 HSP 2 Score: 140.969 bits (354), Expect = 2.611e-33 Identity = 137/469 (29.21%), Postives = 213/469 (45.42%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS----EFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYFGN----IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+EI D ND+ P +L I EN L TD D G N + TN SL S +K+ QL + L DRE Y + + D G+P SS ++ I I+D NDN P FE + E++ +GH + V A DSD PN +TYS+ V I+ N G I + +DRE +F V+AKDNG + + + I V D NDN P I ++ + E + + SDRD G+N G F++RS S + N+ K YF +D E++ + + + +D+GNP ++T ++ ++V D+NDN P F+ L + ++ G V +V ATD D G N + Y++T + + LF I + G++ + +LD + + + +V A D+G PSL T T+ ++ D
Sbjct: 150 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDS------DEKLPQLIVLGNL--DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSAS-----ETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFF----EENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRND 601 HSP 3 Score: 135.191 bits (339), Expect = 1.350e-31 Identity = 148/570 (25.96%), Postives = 241/570 (42.28%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L+I I D NDN P F+ ++PEN A D D G Y L SS + ID I + V G +DRE I +F++ A D G + +V IT D NDN P + +GL ++ ISE V + D+D+ + + G + F++ S+ R +++ + L + KE + IV + + S+ ++++++ D ND+ PV ++ E + V + TD D G N+E + S+ + V +P N G+ ++ DRE+ Y V D G P++ + + + + D NDN P F +FS+ E+ +G+V D D N + S+ D F I + L+ I DRE + Y F ++A D G+P + I I VLD NDN P ++ + S+K ++ R ++ + A D DIG N F + + ++ +EG+I + + ++V V D G PPR T VHI V
Sbjct: 260 LRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMR--LLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLL----DYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGS-VPEGLFEINP--NTGEVRVMS-------QLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPD---NGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDP--RTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 805 HSP 4 Score: 95.5153 bits (236), Expect = 2.571e-19 Identity = 137/567 (24.16%), Postives = 228/567 (40.21%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN--------IGALKSFKENKASIVVIAADGEGRS--NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGI--VIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI 1848
NSP+G+ ++Q + +++ + ++ L+S+D+ G I+V ++DREEI I K A N + + I + D NDN PS + ++ I E++ + +L DRD + V + + E GN+ +L+ LD E IK + + A D G + V++TD+NDN P + Y E E KVL + A D D ++ + I+ S + E + +N + L + + +V AAD S T+ +++ D ND+ P ++ S ++EN V +TV D D+G N+ S+ N F+ + YT + + FDREK S YS + D G P SS ITI + DENDN P+ + D + E + V A+D D N+ + ++I+G F I+ G+I L K + + V+ KD G P + + I V + N+ +
Sbjct: 286 NSPVGH--SVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEIS--ILKFYVQAKDNGPQSKSSKAL-VTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASET---GNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDAD--SGTNAELTYSITGGS-----------VPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTI---------------LSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGG-NPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHV 815 HSP 5 Score: 71.633 bits (174), Expect = 4.502e-12 Identity = 102/416 (24.52%), Postives = 178/416 (42.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP---YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR--IFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRP-VIKVHSSSLKIKENEKS-KILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRY----SVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE----IGIVIAKDSDSS--PNNIITYSIIGDYEV 1668
L++++ D+NDN P F P ++ E + VA D DS + S+ E FE INP +RV+ LDRE + ++F + A+D G +G ++V++ D NDN P+++ Y + E + V + D D+ G R ++S N + +++ + I +I + KE+ S + A DG RS+ I + + D ND+ P V K +SS K + S + V + D D G+NSE D N V G +F+++S + +E ++ + V D GTP ++ ++ I++++ N H E +GH + + IA D D S P++ I ++++G + V
Sbjct: 486 LKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNA--ELTYSITGGSVPEGLFE-------INPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDE----GENARVQLSVEPDNGKFMIQNGTYTILSTI------SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSEL-----DFNIVG-----------GNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVE-----------GLVGHSLYTPLEMDIAGDPDYSRDPHSNILFAVLGGFSV 855
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 253.447 bits (646), Expect = 2.793e-69 Identity = 232/803 (28.89%), Postives = 370/803 (46.08%), Query Frame = 1
Query: 139 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ------PISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR------IFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--------LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQ--VYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ W L L + + V E Q PN+ IG+L S + L + E Y R VD K GDI+ T ++IDRE + C+ P + + + ++ E +IEI+D NDN P F T+ IPEN + F++PVA DRDS G+ Y L + + ++ + P L V+G+LDRE S++ ++ DGG Q + + ITD NDN P++ Y E+ E + VLQ+ A D D G++ + + + S ++ I ++ S+ I LK + + K + + +S++ + + +KD ND+ P I++ L E+ + I V + V+D D+G N+ +C + L S S N ++K F + D E+ Y +E++ D+G P +SS+ + + ++D NDN P F E+ + G ++ V+A D+DS N +TYSI G + F IN N G++ + LDRE D Y+F V A D G P+L + + + VLD NDN P+ + YSF + E+ +G + +D D G+N + V + IQ Y I F DREK + +D G+PPR++ + I VLD NDN P T P +++ +L+ + + V V+A D D GLN + +N+ N LF I S+G+I L K+ K RLVV+ +D+GTP T ++I
Sbjct: 16 LVWILLLL--CCSANVVNTILYQVTEEQPPNTLIGSL--------ASDQGLPDTGHLYKLEVGAPYLR----VDGKTGDIYTTENSIDRESLKDCRNLFEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSD--MGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDN------GPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRS--ASETGNDRKRKYFLQTTT---LLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSP---VGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISF---DREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLD--PRTSPETHVESVEAEDIDIGLNSELDFNIVGGN-PHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHI 782 HSP 2 Score: 140.584 bits (353), Expect = 2.605e-33 Identity = 137/469 (29.21%), Postives = 213/469 (45.42%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS----EFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYFGN----IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+EI D ND+ P +L I EN L TD D G N + TN SL S +K+ QL + L DRE Y + + D G+P SS ++ I I+D NDN P FE + E++ +GH + V A DSD PN +TYS+ V I+ N G I + +DRE +F V+AKDNG + + + I V D NDN P I ++ + E + + SDRD G+N G F++RS S + N+ K YF +D E++ + + + +D+GNP ++T ++ ++V D+NDN P F+ L + ++ G V +V ATD D G N + Y++T + + LF I + G++ + +LD + + + +V A D+G PSL T T+ ++ D
Sbjct: 129 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDS------DEKLPQLIVLGNL--DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSAS-----ETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFF----EENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRND 580 HSP 3 Score: 134.806 bits (338), Expect = 1.812e-31 Identity = 148/570 (25.96%), Postives = 241/570 (42.28%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L+I I D NDN P F+ ++PEN A D D G Y L SS + ID I + V G +DRE I +F++ A D G + +V IT D NDN P + +GL ++ ISE V + D+D+ + + G + F++ S+ R +++ + L + KE + IV + + S+ ++++++ D ND+ PV ++ E + V + TD D G N+E + S+ + V +P N G+ ++ DRE+ Y V D G P++ + + + + D NDN P F +FS+ E+ +G+V D D N + S+ D F I + L+ I DRE + Y F ++A D G+P + I I VLD NDN P ++ + S+K ++ R ++ + A D DIG N F + + ++ +EG+I + + ++V V D G PPR T VHI V
Sbjct: 239 LRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMR--LLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLL----DYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGS-VPEGLFEINP--NTGEVRVMS-------QLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPD---NGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDP--RTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 784 HSP 4 Score: 95.1301 bits (235), Expect = 3.353e-19 Identity = 137/567 (24.16%), Postives = 228/567 (40.21%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN--------IGALKSFKENKASIVVIAADGEGRS--NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGI--VIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI 1848
NSP+G+ ++Q + +++ + ++ L+S+D+ G I+V ++DREEI I K A N + + I + D NDN PS + ++ I E++ + +L DRD + V + + E GN+ +L+ LD E IK + + A D G + V++TD+NDN P + Y E E KVL + A D D ++ + I+ S + E + +N + L + + +V AAD S T+ +++ D ND+ P ++ S ++EN V +TV D D+G N+ S+ N F+ + YT + + FDREK S YS + D G P SS ITI + DENDN P+ + D + E + V A+D D N+ + ++I+G F I+ G+I L K + + V+ KD G P + + I V + N+ +
Sbjct: 265 NSPVGH--SVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEIS--ILKFYVQAKDNGPQSKSSKAL-VTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASET---GNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDAD--SGTNAELTYSITGGS-----------VPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTI---------------LSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGG-NPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHV 794 HSP 5 Score: 71.2478 bits (173), Expect = 6.668e-12 Identity = 102/416 (24.52%), Postives = 178/416 (42.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP---YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR--IFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRP-VIKVHSSSLKIKENEKS-KILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRY----SVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE----IGIVIAKDSDSS--PNNIITYSIIGDYEV 1668
L++++ D+NDN P F P ++ E + VA D DS + S+ E FE INP +RV+ LDRE + ++F + A+D G +G ++V++ D NDN P+++ Y + E + V + D D+ G R ++S N + +++ + I +I + KE+ S + A DG RS+ I + + D ND+ P V K +SS K + S + V + D D G+NSE D N V G +F+++S + +E ++ + V D GTP ++ ++ I++++ N H E +GH + + IA D D S P++ I ++++G + V
Sbjct: 465 LKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNA--ELTYSITGGSVPEGLFE-------INPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDE----GENARVQLSVEPDNGKFMIQNGTYTILSTI------SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSEL-----DFNIVG-----------GNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVE-----------GLVGHSLYTPLEMDIAGDPDYSRDPHSNILFAVLGGFSV 834
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 253.062 bits (645), Expect = 4.717e-69 Identity = 232/803 (28.89%), Postives = 370/803 (46.08%), Query Frame = 1
Query: 139 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ------PISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR------IFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--------LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQ--VYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ W L L + + V E Q PN+ IG+L S + L + E Y R VD K GDI+ T ++IDRE + C+ P + + + ++ E +IEI+D NDN P F T+ IPEN + F++PVA DRDS G+ Y L + + ++ + P L V+G+LDRE S++ ++ DGG Q + + ITD NDN P++ Y E+ E + VLQ+ A D D G++ + + + S ++ I ++ S+ I LK + + K + + +S++ + + +KD ND+ P I++ L E+ + I V + V+D D+G N+ +C + L S S N ++K F + D E+ Y +E++ D+G P +SS+ + + ++D NDN P F E+ + G ++ V+A D+DS N +TYSI G + F IN N G++ + LDRE D Y+F V A D G P+L + + + VLD NDN P+ + YSF + E+ +G + +D D G+N + V + IQ Y I F DREK + +D G+PPR++ + I VLD NDN P T P +++ +L+ + + V V+A D D GLN + +N+ N LF I S+G+I L K+ K RLVV+ +D+GTP T ++I
Sbjct: 29 LVWILLLL--CCSANVVNTILYQVTEEQPPNTLIGSL--------ASDQGLPDTGHLYKLEVGAPYLR----VDGKTGDIYTTENSIDRESLKDCRNLFEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSD--MGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDN------GPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRS--ASETGNDRKRKYFLQTTT---LLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSP---VGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISF---DREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLD--PRTSPETHVESVEAEDIDIGLNSELDFNIVGGN-PHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHI 795 HSP 2 Score: 140.969 bits (354), Expect = 2.609e-33 Identity = 134/465 (28.82%), Postives = 215/465 (46.24%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYFGN----IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+EI D ND+ P +L I EN L TD D G N +L T ++++ + +K+ QL + L DRE Y + + D G+P SS ++ I I+D NDN P FE + E++ +GH + V A DSD PN +TYS+ V I+ N G I + +DRE +F V+AKDNG + + + I V D NDN P I ++ + E + + SDRD G+N G F++RS S + N+ K YF +D E++ + + + +D+GNP ++T ++ ++V D+NDN P F+ L + ++ G V +V ATD D G N + Y++T + + LF I + G++ + +LD + + + +V A D+G PSL T T+ ++ D
Sbjct: 142 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYAL--TTGPEATNLFSLQVAQDSDEKLPQLIVLGNL--DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSAS-----ETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFF----EENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRND 593 HSP 3 Score: 134.806 bits (338), Expect = 1.820e-31 Identity = 148/570 (25.96%), Postives = 241/570 (42.28%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L+I I D NDN P F+ ++PEN A D D G Y L SS + ID I + V G +DRE I +F++ A D G + +V IT D NDN P + +GL ++ ISE V + D+D+ + + G + F++ S+ R +++ + L + KE + IV + + S+ ++++++ D ND+ PV ++ E + V + TD D G N+E + S+ + V +P N G+ ++ DRE+ Y V D G P++ + + + + D NDN P F +FS+ E+ +G+V D D N + S+ D F I + L+ I DRE + Y F ++A D G+P + I I VLD NDN P ++ + S+K ++ R ++ + A D DIG N F + + ++ +EG+I + + ++V V D G PPR T VHI V
Sbjct: 252 LRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMR--LLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLL----DYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGS-VPEGLFEINP--NTGEVRVMS-------QLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPD---NGKFMIQNGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDP--RTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 797 HSP 4 Score: 94.7449 bits (234), Expect = 3.658e-19 Identity = 137/567 (24.16%), Postives = 228/567 (40.21%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN--------IGALKSFKENKASIVVIAADGEGRS--NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGI--VIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI 1848
NSP+G+ ++Q + +++ + ++ L+S+D+ G I+V ++DREEI I K A N + + I + D NDN PS + ++ I E++ + +L DRD + V + + E GN+ +L+ LD E IK + + A D G + V++TD+NDN P + Y E E KVL + A D D ++ + I+ S + E + +N + L + + +V AAD S T+ +++ D ND+ P ++ S ++EN V +TV D D+G N+ S+ N F+ + YT + + FDREK S YS + D G P SS ITI + DENDN P+ + D + E + V A+D D N+ + ++I+G F I+ G+I L K + + V+ KD G P + + I V + N+ +
Sbjct: 278 NSPVGH--SVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEIS--ILKFYVQAKDNGPQSKSSKAL-VTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASET---GNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDAD--SGTNAELTYSITGGS-----------VPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTI---------------LSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGG-NPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHV 807 HSP 5 Score: 71.633 bits (174), Expect = 5.531e-12 Identity = 102/416 (24.52%), Postives = 178/416 (42.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP---YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVR--IFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRP-VIKVHSSSLKIKENEKS-KILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRY----SVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE----IGIVIAKDSDSS--PNNIITYSIIGDYEV 1668
L++++ D+NDN P F P ++ E + VA D DS + S+ E FE INP +RV+ LDRE + ++F + A+D G +G ++V++ D NDN P+++ Y + E + V + D D+ G R ++S N + +++ + I +I + KE+ S + A DG RS+ I + + D ND+ P V K +SS K + S + V + D D G+NSE D N V G +F+++S + +E ++ + V D GTP ++ ++ I++++ N H E +GH + + IA D D S P++ I ++++G + V
Sbjct: 478 LKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNA--ELTYSITGGSVPEGLFE-------INPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDE----GENARVQLSVEPDNGKFMIQNGTYTILSTI------SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPETHVESVEAEDIDIGLNSEL-----DFNIVG-----------GNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVE-----------GLVGHSLYTPLEMDIAGDPDYSRDPHSNILFAVLGGFSV 847
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 275.789 bits (704), Expect = 1.362e-76 Identity = 242/800 (30.25%), Postives = 378/800 (47.25%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + ++LE G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G LDRE S++ + DGG + + I D NDN P++ + Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + V+A D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS PN+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N V S IQ G I+ + DRE + +D G+PPR++ V I VLD NDN P P ++ YL T G+ V V+A D D G+N + Y++ + N +LF I ++G++ L+K + K RLVV+ D+G PS T ++
Sbjct: 53 FLWLFFQLPILGS--STKVAYRVPEEQPPNILIGSLAS-DYGYPDSKHL-----YKLE------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC----FLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTAL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIHLSVEPESGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN-PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVH 817 HSP 2 Score: 124.02 bits (310), Expect = 6.078e-28 Identity = 132/455 (29.01%), Postives = 202/455 (44.40%), Query Frame = 1
Query: 1144 ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYE-VKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-QVYNEG---KIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++EI D ND+ P +L I EN +L TD D G+N S L V ++ L+ + Q I DRE+ Y + + D GTP +SS ++ I I D NDN P FE + E++ +GH + V A DSD N I YS + V+ ++ + G I + +DRE +F+V AKD G ++ I + D NDN P I ++ + E + + SD D G N V + P + QV + G K YF +D E V + + + +D+GNPP ++T ++ ++V DVNDN P F+ L+ + ++ +V EV ATD D G N + Y++ + +FSI D GQI + LD + + V A D+G PSL T ++ I
Sbjct: 163 QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL----IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV-AGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLME----VVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVI 608 HSP 3 Score: 76.2554 bits (186), Expect = 2.717e-13 Identity = 134/576 (23.26%), Postives = 232/576 (40.28%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQ----NQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW------VGLPYRKEISECTTEAKVLQLNAQDKDD-PQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
++ E NSP+G+ + ++ +Q + EI SF S+ R L+ +D+ G I V IDRE++ G ++ D ++ I I D NDN P + I E+V + +L D D GV ++ + ++ D G++ +L+ LD E++K + + A D G + V++TDVNDN P + V P +I++ V++++A D D P + Q+ + I + IF I + + L + V+A D S + T + + + D ND+ P ++ + + EN V +TV D D+G N+ S+ + FV ++NG + ++ FDRE S Y+ + D G P SS +TI + DENDN P + ++ G + V A+D D+ N + YSI E F I+HN G++ L K + R+ + V+ D G+P+ + + + +
Sbjct: 291 MAYEAELPENSPMGHSVLQVKANDSDQGVNAEI--DYSFHQASDTV----RRLLHLDRSTGLITVQGPIDREDV---------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDE---GVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDL-----VMEVSATDADSGPNS---QLHYSILPDPSARG----IFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---------IQNGTGTILSSIS------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 275.404 bits (703), Expect = 2.191e-76 Identity = 242/800 (30.25%), Postives = 378/800 (47.25%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + ++LE G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G LDRE S++ + DGG + + I D NDN P++ + Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + V+A D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS PN+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N V S IQ G I+ + DRE + +D G+PPR++ V I VLD NDN P P ++ YL T G+ V V+A D D G+N + Y++ + N +LF I ++G++ L+K + K RLVV+ D+G PS T ++
Sbjct: 53 FLWLFFQLPILGS--STKVAYRVPEEQPPNILIGSLASDY-GYPDSKHL-----YKLE------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC----FLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTAL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIHLSVEPESGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN-PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVH 817 HSP 2 Score: 124.02 bits (310), Expect = 6.452e-28 Identity = 132/455 (29.01%), Postives = 202/455 (44.40%), Query Frame = 1
Query: 1144 ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYE-VKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-QVYNEG---KIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++EI D ND+ P +L I EN +L TD D G+N S L V ++ L+ + Q I DRE+ Y + + D GTP +SS ++ I I D NDN P FE + E++ +GH + V A DSD N I YS + V+ ++ + G I + +DRE +F+V AKD G ++ I + D NDN P I ++ + E + + SD D G N V + P + QV + G K YF +D E V + + + +D+GNPP ++T ++ ++V DVNDN P F+ L+ + ++ +V EV ATD D G N + Y++ + +FSI D GQI + LD + + V A D+G PSL T ++ I
Sbjct: 163 QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL----IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV-AGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLME----VVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVI 608 HSP 3 Score: 75.8702 bits (185), Expect = 3.714e-13 Identity = 134/576 (23.26%), Postives = 232/576 (40.28%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQ----NQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW------VGLPYRKEISECTTEAKVLQLNAQDKDD-PQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
++ E NSP+G+ + ++ +Q + EI SF S+ R L+ +D+ G I V IDRE++ G ++ D ++ I I D NDN P + I E+V + +L D D GV ++ + ++ D G++ +L+ LD E++K + + A D G + V++TDVNDN P + V P +I++ V++++A D D P + Q+ + I + IF I + + L + V+A D S + T + + + D ND+ P ++ + + EN V +TV D D+G N+ S+ + FV ++NG + ++ FDRE S Y+ + D G P SS +TI + DENDN P + ++ G + V A+D D+ N + YSI E F I+HN G++ L K + R+ + V+ D G+P+ + + + +
Sbjct: 291 MAYEAELPENSPMGHSVLQVKANDSDQGVNAEI--DYSFHQASDTV----RRLLHLDRSTGLITVQGPIDREDV---------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDE---GVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDL-----VMEVSATDADSGPNS---QLHYSILPDPSARG----IFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---------IQNGTGTILSSIS------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 276.944 bits (707), Expect = 3.413e-76 Identity = 242/800 (30.25%), Postives = 378/800 (47.25%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + ++LE G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G LDRE S++ + DGG + + I D NDN P++ + Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + V+A D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS PN+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N V S IQ G I+ + DRE + +D G+PPR++ V I VLD NDN P P ++ YL T G+ V V+A D D G+N + Y++ + N +LF I ++G++ L+K + K RLVV+ D+G PS T ++
Sbjct: 53 FLWLFFQLPILGS--STKVAYRVPEEQPPNILIGSLASDY-GYPDSKHL-----YKLE------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC----FLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTAL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIHLSVEPESGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN-PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVH 817 HSP 2 Score: 124.02 bits (310), Expect = 6.057e-28 Identity = 132/455 (29.01%), Postives = 202/455 (44.40%), Query Frame = 1
Query: 1144 ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYE-VKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-QVYNEG---KIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++EI D ND+ P +L I EN +L TD D G+N S L V ++ L+ + Q I DRE+ Y + + D GTP +SS ++ I I D NDN P FE + E++ +GH + V A DSD N I YS + V+ ++ + G I + +DRE +F+V AKD G ++ I + D NDN P I ++ + E + + SD D G N V + P + QV + G K YF +D E V + + + +D+GNPP ++T ++ ++V DVNDN P F+ L+ + ++ +V EV ATD D G N + Y++ + +FSI D GQI + LD + + V A D+G PSL T ++ I
Sbjct: 163 QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL----IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV-AGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLME----VVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVI 608 HSP 3 Score: 77.0258 bits (188), Expect = 1.634e-13 Identity = 133/575 (23.13%), Postives = 230/575 (40.00%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQ----NQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW------VGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
++ E NSP+G+ + ++ +Q + EI SF S+ R L+ +D+ G I V IDRE++ G ++ D ++ I I D NDN P + I E+V + +L D D GV ++ + ++ D G++ +L+ LD E++K + + A D G + V++TDVNDN P + V P +I++ V++++A D D Q+ + I + IF I + + L + V+A D S + T + + + D ND+ P ++ + + EN V +TV D D+G N+ S+ + FV ++NG + ++ FDRE S Y+ + D G P SS +TI + DENDN P + ++ G + V A+D D+ N + YSI E F I+HN G++ L K + R+ + V+ D G+P+ + + + +
Sbjct: 291 MAYEAELPENSPMGHSVLQVKANDSDQGVNAEI--DYSFHQASDTV----RRLLHLDRSTGLITVQGPIDREDV---------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDE---GVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDL-----VMEVSATDAD--SGPNSQLHYSILPDPSARG----IFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---------IQNGTGTILSSIS------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 275.789 bits (704), Expect = 3.566e-76 Identity = 242/800 (30.25%), Postives = 378/800 (47.25%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + ++LE G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G LDRE S++ + DGG + + I D NDN P++ + Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + V+A D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS PN+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N V S IQ G I+ + DRE + +D G+PPR++ V I VLD NDN P P ++ YL T G+ V V+A D D G+N + Y++ + N +LF I ++G++ L+K + K RLVV+ D+G PS T ++
Sbjct: 53 FLWLFFQLPILGS--STKVAYRVPEEQPPNILIGSLASDY-GYPDSKHL-----YKLE------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC----FLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTAL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIHLSVEPESGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN-PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVH 817 HSP 2 Score: 123.635 bits (309), Expect = 8.621e-28 Identity = 132/455 (29.01%), Postives = 202/455 (44.40%), Query Frame = 1
Query: 1144 ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYE-VKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-QVYNEG---KIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++EI D ND+ P +L I EN +L TD D G+N S L V ++ L+ + Q I DRE+ Y + + D GTP +SS ++ I I D NDN P FE + E++ +GH + V A DSD N I YS + V+ ++ + G I + +DRE +F+V AKD G ++ I + D NDN P I ++ + E + + SD D G N V + P + QV + G K YF +D E V + + + +D+GNPP ++T ++ ++V DVNDN P F+ L+ + ++ +V EV ATD D G N + Y++ + +FSI D GQI + LD + + V A D+G PSL T ++ I
Sbjct: 163 QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL----IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV-AGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLME----VVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVI 608 HSP 3 Score: 76.2554 bits (186), Expect = 2.574e-13 Identity = 133/575 (23.13%), Postives = 230/575 (40.00%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQ----NQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW------VGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
++ E NSP+G+ + ++ +Q + EI SF S+ R L+ +D+ G I V IDRE++ G ++ D ++ I I D NDN P + I E+V + +L D D GV ++ + ++ D G++ +L+ LD E++K + + A D G + V++TDVNDN P + V P +I++ V++++A D D Q+ + I + IF I + + L + V+A D S + T + + + D ND+ P ++ + + EN V +TV D D+G N+ S+ + FV ++NG + ++ FDRE S Y+ + D G P SS +TI + DENDN P + ++ G + V A+D D+ N + YSI E F I+HN G++ L K + R+ + V+ D G+P+ + + + +
Sbjct: 291 MAYEAELPENSPMGHSVLQVKANDSDQGVNAEI--DYSFHQASDTV----RRLLHLDRSTGLITVQGPIDREDV---------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDE---GVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDL-----VMEVSATDAD--SGPNSQLHYSILPDPSARG----IFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---------IQNGTGTILSSIS------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 276.559 bits (706), Expect = 4.091e-76 Identity = 242/800 (30.25%), Postives = 378/800 (47.25%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + ++LE G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G LDRE S++ + DGG + + I D NDN P++ + Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + V+A D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS PN+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N V S IQ G I+ + DRE + +D G+PPR++ V I VLD NDN P P ++ YL T G+ V V+A D D G+N + Y++ + N +LF I ++G++ L+K + K RLVV+ D+G PS T ++
Sbjct: 45 FLWLFFQLPILGS--STKVAYRVPEEQPPNILIGSLASDY-GYPDSKHL-----YKLE------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC----FLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTAL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIHLSVEPESGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN-PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVH 809 HSP 2 Score: 124.02 bits (310), Expect = 7.396e-28 Identity = 132/455 (29.01%), Postives = 202/455 (44.40%), Query Frame = 1
Query: 1144 ELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYE-VKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-QVYNEG---KIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++EI D ND+ P +L I EN +L TD D G+N S L V ++ L+ + Q I DRE+ Y + + D GTP +SS ++ I I D NDN P FE + E++ +GH + V A DSD N I YS + V+ ++ + G I + +DRE +F+V AKD G ++ I + D NDN P I ++ + E + + SD D G N V + P + QV + G K YF +D E V + + + +D+GNPP ++T ++ ++V DVNDN P F+ L+ + ++ +V EV ATD D G N + Y++ + +FSI D GQI + LD + + V A D+G PSL T ++ I
Sbjct: 155 QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL----IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV-AGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLME----VVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVI 600 HSP 3 Score: 77.0258 bits (188), Expect = 1.789e-13 Identity = 133/575 (23.13%), Postives = 230/575 (40.00%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQ----NQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQI------FELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW------VGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
++ E NSP+G+ + ++ +Q + EI SF S+ R L+ +D+ G I V IDRE++ G ++ D ++ I I D NDN P + I E+V + +L D D GV ++ + ++ D G++ +L+ LD E++K + + A D G + V++TDVNDN P + V P +I++ V++++A D D Q+ + I + IF I + + L + V+A D S + T + + + D ND+ P ++ + + EN V +TV D D+G N+ S+ + FV ++NG + ++ FDRE S Y+ + D G P SS +TI + DENDN P + ++ G + V A+D D+ N + YSI E F I+HN G++ L K + R+ + V+ D G+P+ + + + +
Sbjct: 283 MAYEAELPENSPMGHSVLQVKANDSDQGVNAEI--DYSFHQASDTV----RRLLHLDRSTGLITVQGPIDREDV---------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDE---GVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDL-----VMEVSATDAD--SGPNSQLHYSILPDPSAR----GIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---------IQNGTGTILSSIS------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 812
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 252.677 bits (644), Expect = 6.930e-69 Identity = 217/733 (29.60%), Postives = 343/733 (46.79%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G + VD K GDI+ T ++IDRE + CQ P + C+ + + + ++ E QIE+ DINDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G + V A D+DS N + YS+ + + F I+ NG+I + LDRE +D YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N + Y++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 73 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFH---QAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLL--TPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 788 HSP 2 Score: 136.346 bits (342), Expect = 5.705e-32 Identity = 139/580 (23.97%), Postives = 254/580 (43.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ ++ L+ +K + IV + + S+ ++++++ D ND+ PV + + EN K +V +T +D D G N+E SL + ++T ENG + L DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S +++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 244 LRVTVLDTNDNAPKFERPTYEAELSENSPIG--HSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFL-QTTTPLDYEKVKDYT---IEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEP--AAQGLFTISPENGEIRVKTSL--------DREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGE--TVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 797
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 252.677 bits (644), Expect = 6.930e-69 Identity = 217/733 (29.60%), Postives = 343/733 (46.79%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G + VD K GDI+ T ++IDRE + CQ P + C+ + + + ++ E QIE+ DINDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G + V A D+DS N + YS+ + + F I+ NG+I + LDRE +D YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N + Y++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 73 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFH---QAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLL--TPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 788 HSP 2 Score: 136.346 bits (342), Expect = 5.705e-32 Identity = 139/580 (23.97%), Postives = 254/580 (43.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ ++ L+ +K + IV + + S+ ++++++ D ND+ PV + + EN K +V +T +D D G N+E SL + ++T ENG + L DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S +++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 244 LRVTVLDTNDNAPKFERPTYEAELSENSPIG--HSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFL-QTTTPLDYEKVKDYT---IEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEP--AAQGLFTISPENGEIRVKTSL--------DREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGE--TVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 797
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 227.254 bits (578), Expect = 2.029e-60 Identity = 195/666 (29.28%), Postives = 308/666 (46.25%), Query Frame = 1
Query: 511 NDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
NDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G + V A D+DS N + YS+ + + F I+ NG+I + LDRE +D YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N + Y++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 1 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSD--QGANAEIDYTFH---QAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLL--TPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 649 HSP 2 Score: 136.346 bits (342), Expect = 6.521e-32 Identity = 139/580 (23.97%), Postives = 254/580 (43.79%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ ++ L+ +K + IV + + S+ ++++++ D ND+ PV + + EN K +V +T +D D G N+E SL + ++T ENG + L DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S +++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 105 LRVTVLDTNDNAPKFERPTYEAELSENSPIG--HSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFL-QTTTPLDYEKVKDY---TIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEP--AAQGLFTISPENGEIRVKTSL--------DREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGE--TVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 658 HSP 3 Score: 62.003 bits (149), Expect = 4.491e-9 Identity = 82/365 (22.47%), Postives = 148/365 (40.55%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIV--VIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFET 1539
L+++++D+NDN P F + PEN + A D DS + + F + I RV LDRE S+E + A+D G QG ++V + D NDN P+++ Y + E + V + D D G R ++S N + +++ T +IL +L +E +++ + A DG RS + + + D ND+ P I S++ ++++ V+++T D D GIN+E + S + G +FQ+ S G +R + + V +D G P + ++ +++++ N ET
Sbjct: 331 LKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNA--ELVYSLEPEPAAQGLFTISPENGEI----RVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDK----GENARVQLSVEQDNGDFVIQ--NGTGTIL----SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYS----------------IAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLET 663
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 224.557 bits (571), Expect = 1.890e-59 Identity = 220/771 (28.53%), Postives = 364/771 (47.21%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPI---SKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTE-----AKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKA-SIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
+V E N IG+L+K LI +++ +T + F+L + + LI +++ G+I+ T A IDRE++C I ++C + + ++ +++ I DINDN P F I IPEN A +S +SLP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I++++ D NDN P ++ KEI E + V QL+A D D IG R ++ + R+F++ + + + +E+ + ++V+A DG T+ + + D ND+ P I + + ++ + EN + ITV D+D N +C + L ++++ F L + + D E Y+++++ D G P ++ S ++ I + DENDN P F F + S+ E+ G ++ + A D+DS N I+Y + ++ F ++ G + K LDRE +++Y FTV A+DNG P L + + + VLD NDN P + Y+F + ES KH +G + +D D G+N + + I G I + DRE+ + V D G R++T V I V+DVNDN+P F P N +++ + G++V +V A D+D G+N ++Y++ N TK LF I Q+ G I LK+K R++V+A D G P
Sbjct: 29 TVREEMPENVLIGDLLKDLNLSLIPDKSLTTPM----QFKLVYKTGDV---PLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFI----EKEIEVSIPENAPIGSSVTQLHATDAD----IGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQ---------FLLET--AAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYML--GFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLP---KHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDP-QSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSN-YSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGN-TKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 223.787 bits (569), Expect = 1.957e-59 Identity = 220/771 (28.53%), Postives = 364/771 (47.21%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPI---SKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTE-----AKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKA-SIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
+V E N IG+L+K LI +++ +T + F+L + + LI +++ G+I+ T A IDRE++C I ++C + + ++ +++ I DINDN P F I IPEN A +S +SLP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I++++ D NDN P ++ KEI E + V QL+A D D IG R ++ + R+F++ + + + +E+ + ++V+A DG T+ + + D ND+ P I + + ++ + EN + ITV D+D N +C + L ++++ F L + + D E Y+++++ D G P ++ S ++ I + DENDN P F F + S+ E+ G ++ + A D+DS N I+Y + ++ F ++ G + K LDRE +++Y FTV A+DNG P L + + + VLD NDN P + Y+F + ES KH +G + +D D G+N + + I G I + DRE+ + V D G R++T V I V+DVNDN+P F P N +++ + G++V +V A D+D G+N ++Y++ N TK LF I Q+ G I LK+K R++V+A D G P
Sbjct: 29 TVREEMPENVLIGDLLKDLNLSLIPDKSLTTPM----QFKLVYKTGDV---PLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFI----EKEIEVSIPENAPIGSSVTQLHATDAD----IGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQ---------FLLET--AAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYML--GFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLP---KHGTVGLITVTDPDYGENSAVTLSILDVNDQFTID-PQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSN-YSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGN-TKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 251.521 bits (641), Expect = 1.115e-67 Identity = 217/733 (29.60%), Postives = 342/733 (46.66%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G + VD K GDI+ T ++IDRE + CQ P C+ + + + ++ E QIE+ DINDN P+F T+ IPEN S F +P+A DRD+ GV Y L++ + ++ + P L V+G+LDRE S++ + DGG ++ +T D NDN P++ Y E+SE + V+Q+ A D D Q +I + Q E++ R+ + + + + G + + V+A D +S + + +KD ND+ P I++ L I E+ + V + V+D D+G N+ +C + V S + +KK F + P D EK Y++E++ D+G P +SS+ + + + D NDN P F + E+ K G I + A D+DS N + YS+ + K F I+ G+I + LDRE ++ YE V A D G P+L + + + VLD NDN P+ S Y+F ++E+ +G + D D G+N + V + IQ G I+ + DRE+ + +D G PPR+A V I VLD NDN P T P +H L T G V +V A D D G+N +IY++ N LF I S G I L+K+++ + RLVV+ D+G P T +++
Sbjct: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTF---HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP---VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLL--TPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810 HSP 2 Score: 136.346 bits (342), Expect = 4.706e-31 Identity = 141/582 (24.23%), Postives = 254/582 (43.64%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII---GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNR 2157
L++ ++D NDN P F+ ++ EN S+ K DS++ + + +D + + V G +DRE++ + F + A D G N + +++V + D+NDN P + +GL ++ ISE E V + D+D+ + + G + F++ + S+ + +++ T + Y + K+ IV + + S+ ++++++ D ND+ PV + + EN K ++ IT +D D G N+E SL + ++T E G Q+ + DRE+ Y ++V+ D G+P++ + + + + D NDN P F FS+ E+ +G+V D D N + S+ GD+ ++ N G I + DRE + Y F ++A D G P + + I VLD NDN P I+ ++ S K++ R + + ++ A D D G N + + + Q+ + G I I+R ++V V D G PPR T VH+ V + NR
Sbjct: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIG--HSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGL---ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDY------EKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEP--AAKGLFTISPETGE----IQVKT----SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGE--TVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANR 819
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q9BZA8|PC11Y_HUMAN (Protocadherin-11 Y-linked OS=Homo sapiens OX=9606 GN=PCDH11Y PE=1 SV=1) HSP 1 Score: 232.261 bits (591), Expect = 7.829e-61 Identity = 233/790 (29.49%), Postives = 364/790 (46.08%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISKCLTGAFLNYIIFADHQIFEL---QIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSP--LENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
+ + + V S K Y ++ E N IGNL+K LI N++ +T T F+L + + LI +++ G+I+ T A IDRE++C I + + + +IF L + I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ LEN Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P
Sbjct: 41 IFAVLLVCVVFHSGAQEKNY-TIREEIPENVLIGNLLKDLNLSLIPNKSLTT----TMQFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA-------------YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN-YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 791
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 230.335 bits (586), Expect = 3.270e-60 Identity = 226/767 (29.47%), Postives = 358/767 (46.68%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISKCLTGAFLNYIIFADHQIFEL---QIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
++ E N IG+L+K LI N++ +T + F+L + + LI +++ G+I+ T A IDRE++C I + + + +IF L + I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ F L + Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y+F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P
Sbjct: 29 TIREEMPENVLIGDLLKDLNLSLIPNKSLTTAM----QFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ---------FLLET--AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSN-YSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 230.335 bits (586), Expect = 3.299e-60 Identity = 226/767 (29.47%), Postives = 358/767 (46.68%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISKCLTGAFLNYIIFADHQIFEL---QIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
++ E N IG+L+K LI N++ +T + F+L + + LI +++ G+I+ T A IDRE++C I + + + +IF L + I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ F L + Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y+F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P
Sbjct: 29 TIREEMPENVLIGDLLKDLNLSLIPNKSLTTAM----QFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKS-----QNIFGLDVIETPEGDKM-PQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ---------FLLET--AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSN-YSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 229.565 bits (584), Expect = 5.946e-60 Identity = 228/770 (29.61%), Postives = 362/770 (47.01%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIK-----LIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEICQPISK---C---LTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRII--VEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG-ALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVH------SSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
++ E N IG+L+K LI N++ +T + F+L + + LI +++ G+I+ T A IDRE++C I + C + A L IF ++ +++ I DINDN P F I IPEN A +S+++LP A D D GV+ Y L +N F L G+ + P L V +LDRE ++ + DGG Q I V +TD NDN P + I E V QL+A D D IG + S ++ + R+F++ + + I L + ++V+A+DG + + + D ND+ P I + + ++ + EN + ITVTD+D N +C + L ++++ F L + Y D E Y+++++ D G P ++ S ++ I + DENDN P F F T SI E+ G ++ V A D+DS PN I Y ++G E G + + K LDRE +D+Y FT+ AKDNG P L + + + ++D NDN P + Y+F + E+ R H +G + +D D G N + + D + ++ +I + DREK + V D G R+++ V I V+DVNDN+P F P N ++Y + G++V +V A D D G+N + Y++ N T+DLF+I Q G I L +K D R++V+A D G P
Sbjct: 29 TIREEMPENVLIGDLLKDLNLSLIPNKSLTTAM----QFKLVYKTGDV---PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF---RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS-----QNMFGLDVIETPEGDKM-PQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD----IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ---------FLLET--AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR---HGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSN-YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A4E0S0C6 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000360 PE=4 SV=1) HSP 1 Score: 301.212 bits (770), Expect = 1.167e-80 Identity = 239/850 (28.12%), Postives = 382/850 (44.94%), Query Frame = 1
Query: 346 LISVDQKKGDIWVTSAIDREEICQPI----SKCL-------------TGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKT-------IKIPENVARSSEFSLPVAKDRDSEKYGVXXXX-XXXXXXXXXENYFELIDHGNN--------------------------INPYLRVIGDLDRENI-KSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWV------------------------GLPYRK-----EISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNY--EMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSS-LKIKENEKSKI-LVTRITVTDED--QGINSEFSCSLNDTNFVSLDSMYTSPLEN------------------GGQK---------KIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFK---------------------TFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--------------DYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGE-PNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGT--FRFRVRSRSTPID----------------IQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTAT-TTVHIEVLDVNDNRPKFTYPLLNAHNY-------------------------------LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
L+ ++ G + T +DRE +C +C + F ++AD L + ++D+NDN P F I + E + LP A D D++++GV++Y + ++ +F+++ + + P LR I LDRE F F+L A+D G +G+ + + + DVND+ P+W G R+ + ECTT+ K+++L AQDKDDPQ GG+I F++SE+S + + R +++ LYL L+ + +IVV+A+DG GR+ E L I+DCNDHRP+I + ++ + I E + LV+ ITV D D NS+FSC LNDT ++ L + P + GG++ +++L S + FDRE ++ Y+V C D G+P++++S ITI I D NDN P F T F++SEDA+ G IG V A D DS N + Y+++ + + F + G++HL LDRE + YEF V A D+G+ L+ + ++I V DVND P Y F++VES+ H +G LNA+D D+G+NG+ +R V R + + ++V ++G+I +G +DRE++ I V V DNG P +T TTV I VLD+NDN+P+F P A LN++ D + G+++ + +A D D+G NG++ + L
Sbjct: 122 LVQLEPSTGAVRFTVPLDRERLCPDTIGTDQRCTISLLVAIHLTPINSSHFKPLTVYAD-----LTVLVLDVNDNAPYFTSSNSADSAPLAVITVDEECPIGTMIQLPQATDPDTQEHGVQRYEFHPTSTAVRVREHFDVVQFRHQPGLRCEDVTSVQLEMIQSVAPADPRPVVPCLRTIRRLDRETAGDQFHFNLIATDTNGKRGEIAVQLLVRDVNDHAPEWATKLELFDSSSRSHWISASPSDPAHGTESRQTHYTFSVPECTTQHKLIRLEAQDKDDPQQDGGKITFRLSEHSPDRLPTTLRRRLFVSNDHLYLTDRGLRGLAQPNLTIVVVASDGAGRNTEAWFHLRIEDCNDHRPMILIQNTDYITIPEESAGQSHLVSLITVRDFDLVTSPNSQFSCFLNDTTYLELKEVVAGPTADDRDLLHSHSHQGDEITSTGGKEDLSSRRGRWSVYRLGSRSEISFDRETSALYTVMFECIDKGSPSLTASRPITIHIEDINDNAPQFITRCAPLPLSQNTKDIKPNRPCTPQFVFTVSEDAERGILIGSVRAVDLDSGENARVEYTLLSLHNNSTVPDSNESEVFRPETLFTVTPMGELHLLGELDRESQSYYEFLVVATDHGKRQRLSSTATVQITVADVNDCAPVFRGDYVFEVVESYGSSTIHQVLGTLNATDADLGRNGSVHYRLAVHPRESGLSGLSKSMSDSAVPGAQLVKVSHDGQITVYGVVDREQITMIMVDVIAEDNGVPLHMSTMTTVTIHVLDLNDNKPRFVQPEFTAGRLPSSFSNQKPERFNTLGLPPSFEALSSDATYKLNLSLDTSIGTLITKFEAFDPDYGPNGTLTFEL 966
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A3Q3FN09 (Protocadherin 1a OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1) HSP 1 Score: 279.641 bits (714), Expect = 6.680e-75 Identity = 250/803 (31.13%), Postives = 386/803 (48.07%), Query Frame = 1
Query: 127 LMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISKCLTGAFLNYIIFA-------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
L +FW + +E S+ LY V+E Q PN+ IG+L Q S + ++LE G + VD K GDI+ T IDRE + C+ ++K T +L + + ++ E +IE+ DINDN P F TI +PEN + FS+P+A DRDSE+ GV Y L + + ++ D P L V+G+LDRE S++ + A DGG Q + V +TD NDN P++ Y E+SE + VLQ+ A D D G+I + + + ++RI T I+Y+ G L + + S V+A D + +S++T + +E+ D ND+ P +++ HS + I E+ V + V+DED+G N+ +C + L S +N ++K F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN P F +E+ + G ++ V A D+DS N + Y+I+ D +K F I+ N G++ LDRE K+RYEF V A D G P + + + VLD NDN P+ S YSF ++E+ +G + D D G+N V +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P + ++ ++ + S V V+A D+D G N ++YN+ N LF I S G+I L K++ K RLVV D+G P AT ++I
Sbjct: 5 LRAVLFW--VVVLHCGSAEGSI-LY-RVQEEQPPNTLIGSLAA-DQGLPDSGHL-----YKLE------VGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLAKGKT-CYLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSSALLRVVVTDANDNAPKFEKSSYEAEVSENSPVGHSVLQVKANDSD--MGPNGEIEYTLHQAVDPVPKLLRIDRST-GIIYVK-GPLDREEISSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDEDEGENAVVTCVVAGDVPFQLRPASDSTADN--KRKYFLQTTTP---LDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPIFSPTLFEVDFAEENQPGEKVLDVTASDADSGTNAELLYNIVADSSIKGLFEIDPNTGEVRARSPLDREHKERYEFRVTAADKGSPVHKGTATVVVKVLDRNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVQDMDKGENARVHLSVEPDGGKFVVQ-NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVITKP--SNSSFRRLSPLASPDSHVEVVEAEDQDSGPNAELVYNIAGGN-PYSLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHI 774 HSP 2 Score: 129.413 bits (324), Expect = 1.863e-26 Identity = 148/586 (25.26%), Postives = 245/586 (41.81%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE---CTTEAKVLQLNAQDKDDPQTI----GGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS-------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L++ + D NDN P F+ ++ EN A D D G +Y L + + ID I + V G LDRE I S F++ A D G K + +E+TD NDN P + +GL E ISE T ++Q++ +D+ + + G + F++ S + R +++ T + Y + ++ + IV + + S+ ++++++ D ND+ P+ + E + V +T +D D G N+E N V+ S+ K +F+++ G DRE RY V D G+P + + + + D NDN P F +FS+ E+ +G+V +D D N + S+ G + V+ N G I + DRE + Y F ++A D GEP + + I VLD NDN P I+ ++ SF+ + H + + A D+D G N + + R +P + G+I + R+ ++V V D G PPR AT VHI V
Sbjct: 230 LRVVVTDANDNAPKFEKSSYEAEVSENSPVGHSVLQVKANDSDMGPNGEIEYTLHQAVDPVPK--LLRIDRSTGI---IYVKGPLDREEISSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDEDEGENAVVTCVVAGDVPFQLRPASDSTADNKRKYFLQTTTPLDYERV------RDYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPIFSPTLFEVDFAEENQPGEKVLDVTASDADSGTNAELLY-----NIVADSSI----------KGLFEIDPNTGEVRARSPLDREHKERYEFRVTAADKGSPVHKGTATVVVKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDKGENARVHLSVEPDGGKFVVQ-----NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVITKPSNSSFRRLSPLASPDSHVEV--VEAEDQDSGPNAELVYNIAGGNPYSLFRISP------SSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 776 HSP 3 Score: 91.6633 bits (226), Expect = 7.144e-15 Identity = 141/604 (23.34%), Postives = 241/604 (39.90%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH-------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHG-----NNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSF----KENKA--SIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGD--YEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE 1893
S E NSP+G+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI + Y++ D + F + IE+ D NDN P+ + E I E++ + +L D D + V + F+L N +L+ LD E ++ + + A D G + V++TDVNDN+P + + + +E KVL + A D D ++ + I +S I +F I N G +++ +E+K V AAD T+ +++ D ND+ P + S + EN V +TV D D+G N+ S+ E G K + Q + + + FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + +V A+D DS PN + Y+I G Y + F I+ +G+I L K + R+ + V D G+P + + + I V + N+ + + +R+
Sbjct: 248 SYEAEVSENSPVGH--SVLQVKANDSDMGPNGEIEYTLHQAVDPVPKLLRIDRSTGIIYVKGPLDREEIS---------SLSFYVVARDKGPQPKSSKTF-VTIEVTDQNDNAPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDEDEGENAVVTCVVAGDVP------FQLRPASDSTADNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPIFSPTLFEVDFAEENQPGEKVLDVTASDAD--SGTNAELLYNIVADSS----IKGLFEIDP-----NTGEVRARSPLDREHKERYEFRVTAADKGSPVHKGTATVVVKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDKGENARVHLSV----------------EPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVITKPSNSSFR--RLSPLASPDSHVEVVEAEDQDSGPNAELVYNIAGGNPYSL---FRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNVSLVEALVGHSLYTPLDRD 801
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A3Q2XMI2 (Protocadherin 1a OS=Hippocampus comes OX=109280 PE=4 SV=1) HSP 1 Score: 279.256 bits (713), Expect = 1.099e-74 Identity = 247/803 (30.76%), Postives = 389/803 (48.44%), Query Frame = 1
Query: 127 LMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISK---C---LTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAA-GSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
L+ +FW L L +S + V+E Q PN+ IG+L Q S + ++LE G + VD K GDI+ T IDRE + C+ + + C + + I ++ E +IE+ DINDN P F TI +PEN + FS+P+A DRDS++ GV Y L + + ++ D P L V+G+LDRE S++ + DGG Q + V +TDVNDN+P++ L Y E+ E + VLQ+ A D D G+I + + + ++RI T I+Y+ G L + + S V+A D + +S++T + +E+ D ND+ P +++ HS + I E+ V + V+D+D+G N+ +C + L + S +N ++K F + P D E+ Y V ++ D+G P +S + + + ++D NDN P F +E+ + G ++ VIA D+DS N + YSI+ D +K F I+ N G++ + LDRE K+ YEF V A D G P + + I VLD NDN P+ S YSF ++E+ +G + D D G+N R V S +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P +++ + +A+ S V V+A D D G N +++++ N + LF I S G+I L K++ K RLVV+ D+G P+ AT ++I
Sbjct: 14 LLVMLFWLLVLL----RSSAEGSILYRVQEEQPPNTLIGSLAA-DQGLPDSGHL-----YKLE------VGAPYLRVDGKTGDIFTTEIPIDRETLRDCRMLVRGKPCYLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSSVLTISVPENTIMGALFSIPLATDRDSDRNGVSDYALTAGQDAATLFGLQVADDRGGKIPQLIVLGNLDRELKDSYDLTIKTVDGGNPQRYSSALLRVVVTDVNDNSPKFEKLTYEAEVLENSPVGHSVLQVKANDSD--MGPNGEIEYTLHQAGDPVPKLLRIDRST-GIIYVK-GPLDREEIDSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNPPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDQDEGENAVVTCVVAGDVPFQLRPISDSSSDN--KRKYFLQTTTP---LDYERVKDYRVAIVAVDSGNPALSGTNSLKVQVTDVNDNAPVFSPTLFEVEFAEENQPGEKVLDVIASDADSGTNADLLYSIVADTSIKGLFEIDPNTGEVRASNPLDREHKEHYEFRVTAADKGSPVHKGTASVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVMDVDKGENAHVRLSVESDGGKFVVQ-NGTGTILSSISFDREKESSYTFRLKALDGGQPPRSSYVGVTINVLDENDNDPVVTKP---SNSSFRLLSPLASPDSHVEIVEAEDLDSGPNAELVFSIAGGNPYQ-LFRISPSSGEITLAKEMARKYGGLHRLVVKVSDRGKPTRHATALVHI 783 HSP 2 Score: 124.79 bits (312), Expect = 5.546e-25 Identity = 154/625 (24.64%), Postives = 252/625 (40.32%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLR---------VIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE---CTTEAKVLQLNAQDKDDPQTI----GGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL-NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS-------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAA 2223
L++ + D+NDN P F+ ++ EN A D D G E + L G+ + LR V G LDRE I S F++ A D G K + +E+TD NDN P + +GL E ISE T ++Q++ QD+ + + G + F++ S + R +++ T + Y + K+ + +IV + + S ++++++ D ND+ PV ++ E + V + +D D G N++ S+ DT+ K +F+++ G DRE Y V D G+P + + I + D NDN P F +FS+ E+ +G+V D D N + S+ G + V+ N G I + DRE + Y F ++A D G+P + + I VLD NDN P ++ ++ SF+++ H I + A D D G N F + R +P + G+I + R+ ++V V D G P R AT VHI V + N F L+ Y + D+A
Sbjct: 239 LRVVVTDVNDNSPKFEKLTYEAEVLENSPVGHSVLQVKANDSDMGPNG--------------EIEYTLHQAGDPVPKLLRIDRSTGIIYVKGPLDREEIDSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNPPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDQDEGENAVVTCVVAGDVPFQLRPISDSSSDNKRKYFLQTTTPLDYERV------KDYRVAIVAVDSGNPALSGTNSLKVQVTDVNDNAPVFSPTLFEVEFAEENQPGEKVLDVIASDADSGTNADLLYSIVADTSI----------------KGLFEIDPNTGEVRASNPLDREHKEHYEFRVTAADKGSPVHKGTASVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVMDVDKGENAHVRLSVESDGGKFVVQ-----NGTGTILSSISFDREKESSYTFRLKALDGGQPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRLLSPLASPDSHVEI--VEAEDLDSGPNAELVFSIAGGNPYQLFRISP------SSGEITLAKEMARKYGGLHRLVVKVSDRGKPTRHATALVHIYVNETISNV-SFVEALVGHSLYTPLDRDIAG 813 HSP 3 Score: 97.8265 bits (242), Expect = 1.110e-16 Identity = 144/578 (24.91%), Postives = 239/578 (41.35%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH-------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL--IDHGNNINP---YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSF----KENKA--SIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
L+ E NSP+G+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI + Y++ D + F + IE+ D NDN P+ + E I E++ + +L D+D + V + F+L I ++ N +L+ LD E +K + + A D G G + V++TDVNDN P + + E +E KVL + A D D + + I ++ I +F I N G +++ +E+K V AAD ++ T + IK D ND+ P + S + EN V +TV D D+G N+ S+ E+ G K + Q + + + FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + IV A+D DS PN + +SI G + F I+ +G+I L K + R+ + V+ D G+P + + + I V
Sbjct: 256 LTYEAEVLENSPVGH--SVLQVKANDSDMGPNGEIEYTLHQAGDPVPKLLRIDRSTGIIYVKGPLDREEI---------DSLSFYVVARDKGPQPKSSKTF-VTIEVTDQNDNPPAVEIRGIGLVTHSEGVANISEDMPVGTAVALVQVSDQDEGENAVVTCVVAGDVP------FQLRPISDSSSDNKRKYFLQTTTPLDYERVKDYRVAIVAVDSGNPALSGTNSLKVQVTDVNDNAPVFSPTLFEVEFAEENQPGEKVLDVIASDAD--SGTNADLLYSIVADTS----IKGLFEIDP-----NTGEVRASNPLDREHKEHYEFRVTAADKGSPVHKGTASVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVMDVDKGENAHVRLSV----------------ESDGGKFVVQNGTGTILSSISFDREKESSYTFRLKALDGGQPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRL--LSPLASPDSHVEIVEAEDLDSGPNAELVFSIAGGNPY-QLFRISPSSGEITLAKEMARKYGGLHRLVVKVSDRGKPTRHATALVHIYV 785
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A068WE58 (Protocadherin gamma B1 OS=Echinococcus granulosus OX=6210 GN=EgrG_000834200 PE=4 SV=1) HSP 1 Score: 280.026 bits (715), Expect = 1.203e-74 Identity = 251/835 (30.06%), Postives = 365/835 (43.71%), Query Frame = 1
Query: 130 MFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQP-------------ISKCLTGAFLNYIIFADHQIFE-LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXX-----------XXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK---------------------------VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSS-----------------LKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQK----KIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMS-SSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN---HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI------STSYSFKIVESWEREH-KHFYIGKLNASDRDIGQNGTFRFRVRS-------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNG--NPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHN------YLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS 2337
MF + W +F + ++ E ++EN + IG LI +Q+Q T L + + Y I + G + IDRE ICQ S AFL +I + + E +Q+ IID+NDN P F+P TI +PE+ F LP AKD D K G+ ++ + YF L N P LR I LD E ++ + L+A DGGG I VEI DVNDN+PQWVGLPY + EC +++ ++QL A D D + G I+FK+ + + + ++ + + Y+ IG L K SI V A DG G +N T I++ ++DCND+ P I V S S + I E + +I + ITV+D D G N+ SC + N V + PL+ +F L G+ FDRE SR V ++C D G P + + +++ I + D NDN P F+ + E+ G G V A D D N + YSI T G+I + LDRE K Y TVEA D G+P L+ S + I VLDVND+ P S F+I ES+++E +IG++NA+D D G NGT F ++ + P ++ +G++ G +DREK + +V V V D G + T+ V I + D NDN P FT P + LN T D+ S + + A D D NG + + L + + F I S
Sbjct: 1 MFALTWTVFVI-PLISCEAPYMHQFYIKENTPAGTLIGQLI--VQHQKTFTS--------LAGQPLSEY----ILIHPTNGSMLAIQTIDREAICQNDESTNSSLVLHRFESPSCEVAFLVHITTNEESLLETVQLTIIDMNDNSPIFEPSSVTISVPESSPIGGLFYLPPAKDADLGKNGISSYHLSRIHSDSGPQACPSYTANDDGYFTLSMTDEN-TPQLRQISGLDYEKFQNLFYCLHAYDGGGLTSALLIAVEIQDVNDNSPQWVGLPYHVHLRECAQQSQQSLWKTSAELRSFLRLSGFAYDTPFRFLIQLAAIDADSKE--NGLIKFKVVQRKSDIQASYKVVVHGDKV-YI-IGQLDYETTPKFSIAVEAKDGGGLTNVTNIDVTLEDCNDNTPKITVTSLSPLPRENLSDWSYYKLTDIWISEEDGREIKLATITVSDADTGENAAVSCDIEWNNLVCTNPFSLVPLKTPAAAIRVPTVFMLLKRDGIKFDREATSRVQVTIVCADRGRPQANIARQMVDIGVWDINDNAPKFKHR-GDIGVQENEPDGTVAGYVHASDIDFGRNAALKYSIKNCKHNVSTLSFTIDERTGKISTLRSLDRENKAVYCVTVEAVDEGDPQLSSSVDVNITVLDVNDSPPVFQGNKNESGRIVFEIPESFDQERLMERFIGQVNATDADSGANGTLEFSIKQTPGPFWHSNPPAYFRITRKGQLYVDGVLDREKQQEHEVTVVVSDTGAFHQRLTSEIGVTIRLQDQNDNSPVFTEPGALSKGPHAGPATLNTTHDVTVNSSILRICAKDNDLQENGKLNFTLRCAKYLRPYFGIGS 814 HSP 2 Score: 89.7373 bits (221), Expect = 2.981e-14 Identity = 128/522 (24.52%), Postives = 212/522 (40.61%), Query Frame = 1
Query: 1138 TIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIF----------QLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF-----------------------ETEFKTF----SISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG-DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYS------------FKIVESW--EREHKHFYIGKLNASDRDIGQNGTFR-------------FRVRSRSTPID-IQVYNEGKIIYFGNI--DREXXXXXXXXXXXXXNGNP-PRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD---GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDS 2481
T++L I D ND+ P+ + S ++ + E+ L D D G N S L+ + S P F QL I GL +++ + Y + D G ++S+ +I + I D NDN P + E ++F + D I + A D+DS N +I + ++ +++ ++ + H ++++ LD E ++ VEAKD G L + I + + D NDN P+I+ TS S +K+ + W E + + + + SD D G+N F + TP I+V ++ I DRE ++ V + D G P A V I V D+NDN PKF + + + ++ G++ G V A+D DFG N ++ Y++ N H S D G+I + LD + K + VEA D+G P LS++ + I DS
Sbjct: 118 TVQLTIIDMNDNSPIFEPSSVTISVPESSPIGGLFYLPPAKDADLGKNGISSYHLSRIH--SDSGPQACPSYTANDDGYFTLSMTDENTPQLRQISGLDYEKFQNLFYCLHAY--DGGG--LTSALLIAVEIQDVNDNSPQWVGLPYHVHLRECAQQSQQSLWKTSAELRSFLRLSGFAYDTPFRFLIQLA-AIDADSKENGLIKFKVVQRKSDIQASYKVVVHGDKVYIIGQLDYETTPKFSIAVEAKDGG--GLTNVTNIDVTLEDCNDNTPKITVTSLSPLPRENLSDWSYYKLTDIWISEEDGREIKLATITVSDADTGENAAVSCDIEWNNLVCTNPFSLVPLKTPAAAIRVPTVFMLLKRDGIKFDREATSRVQVTIVCADRGRPQANIARQMVDIGVWDINDNAPKFKH-----RGDIGVQENEPDGTVAGYVHASDIDFGRNAALKYSIKNCKHNVSTLSFTIDERTGKISTLRSLDRENKAVYCVTVEAVDEGDPQLSSSVDVNITVLDVNDS 625
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A1L8GVL1 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=XELAEV_18021541mg PE=4 SV=1) HSP 1 Score: 281.182 bits (718), Expect = 1.302e-74 Identity = 244/800 (30.50%), Postives = 377/800 (47.12%), Query Frame = 1
Query: 142 FWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVT-SAIDREEI--CQ---PISKCLTGAFLNY------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLY 2454
F LFF ++ S S K+ V E Q PN IG+L S + K + G + VD K GDI+ T ++IDRE + CQ P KC FL + ++ ++ + QIEI+DINDN P+F T+ IPEN F +P A DRDS GV Y L + ++ + + P L V+G+LDRE S++ + DGG + + I D NDN P++ L Y E+ E + VLQ+ A D D Q + +I + + S + + R+ ++ S + + G + VIA D ++ T + + I+D ND++PVI++ L I E+ + V + V+D D+G+N+ +C + V S + +KK F L + L D E Y++E++ D+G P +SS+ + + ++D NDN P F E+ I + V A D+DS N+ + YSI+ D + F IN + GQI +N +LDRE ++ Y+F V A D G P+L + + I VLD NDN P+ + Y+F ++E+ R +G + D D G+N + V S IQ G I+ + DRE + +D G+PPR+A V I VLD NDN P P ++ YL T G+ V V+A D D G+N ++Y++ + N +LF I S +G++ L+K + K RLVV D+G PS T ++
Sbjct: 9 FLWLFFQLPILGS--SSKVAYRVPEEQPPNILIGSLASDY-GYPDSKHLYKLE-----------LGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGQKC----FLEFEVSMTDLMSPVPRLLDGQIEILDINDNTPNFNAPVITLSIPENTMVGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGNLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKLAYEAELPENSPMGHSVLQVKANDSD--QGVNAEIDYSFHQAS---DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVIAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVV--AGDVPFQLKQVSDTGSDSKKKYF-LQTTTSL--DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDMNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGSNSRLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAADKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSP---VGMVTVIDADKGENAHIQLSVEPDSGEFVIQ-NGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSAYVGVTINVLDENDNAPVIVVPSNISYKYL--TPQTHPGTQVNWVRAEDMDTGINAELVYSIASGN-PFELFQISSNNGEVTLEKAIIRKHYGLHRLVVRVNDKGKPSRHGTALVH 773
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 275.404 bits (703), Expect = 5.093e-76 Identity = 254/816 (31.13%), Postives = 393/816 (48.16%), Query Frame = 1
Query: 118 LFGLM-FKMFWQLFFLYTV--VKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISKCLTGAFLNYIIFA-------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSLK--------IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDN-----PPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
L G+M F + W L F V + S LY V E Q PN+ IG+L Q S + ++LE G + VD K G+I+ T IDRE + C+ K FL + + ++ E +IE+ DINDN P F T+ + EN + F++P A DRD+E+ GV KY L + + ++ + P L V+G+LDRE S++ + A DGG + V ITD NDN PQ+ Y E+SE + VLQ+ A D D +G G+I + I + S + + ++ I S +++ G L + + VIA D +S+ T + +E+ D ND+ P +++ L+ I E+ V + V+D+D+G N+ +C + L S ++N +KK F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN PP FE EF +E+ + G ++ VIA D+DS N + YSII D + F I+ +G++ LDRE K+RYEF V A D G P+ + + I VLD NDN P+ + +SYSF ++E+ +G + D D G+N + V +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P + ++ ++ A S+V V+A D D+G N ++Y++ N + + SDG+I L K+L K RLVV+ D+G PS A ++I
Sbjct: 33 LGGVMDFSVGWFLLFALLVDSINSALGGILY-HVREEQPPNTLIGSLAA-DQGLPDSGHL-----YKLE------VGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKP---CFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSD----LGPNGEIEYTIHQAS---DPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDN--KKKYFLQTTTP---LDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEF-----AEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSP---VGMVTVLDMDKGENAQVQLSVEPDVGNFVVQ-NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKP--SNSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHI 809 HSP 2 Score: 132.109 bits (331), Expect = 1.233e-30 Identity = 130/461 (28.20%), Postives = 210/461 (45.55%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIST------SYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYF 2466
+E++D ND+ P +L ++EN TD D N L+ S ++++ + N +K+ QL + L DRE Y + + D GTP+ SS ++ + I+D NDN P FE +SE++ +G+ + V A DSD PN I Y+I V + I + G I + LDRE ++F V A+D G + + + I V D NDN P + ++S + E + + SD+D G+N G F++R D V N+ K YF +D E++ V + +D+GNP ++T ++ ++V D NDN P F+ PL + ++ G V +V A D D G N ++Y++ + T+ LF I S G++ + LD + K V A D+G PS T T+ I+
Sbjct: 155 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEAS--ALFSLQMANDRGEKLPQLIVLGNL--DRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAG---DSSVDNKKK--YFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFE----VEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVL 602 HSP 3 Score: 91.6633 bits (226), Expect = 3.329e-18 Identity = 141/573 (24.61%), Postives = 235/573 (41.01%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHG-----NNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLND--TNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS 1851
NSP+G ++Q + +++ + +++ ++ +++ G I V +DREEI +F ++I D + IE+ D NDN P+ + + I E++ + +L D+D + V + F+L G N +L+ LD E I+ + + A D G + V++TD NDN+P + + E +E KVL + A D D ++ + I +S + F I S + L + + V AAD S+ T + IK D ND+ P + S S + EN V +TV D D+G N++ S+ NFV ++NG + ++ FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + +V A+D D N + YSI G E F I+ +G+I L K L R+ + V+ D G+P+ + I ++ + VN+ I +S
Sbjct: 291 NSPVG--YSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEIS---------SFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDAD--SGTNAELVYSIIADSSTRGL----FEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDVGNFV---------VQNGTGTILSSIS------FDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNSSFR--RLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGG-NPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRH---AIALVHIYVNETISNVS 819
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 272.707 bits (696), Expect = 6.093e-76 Identity = 251/807 (31.10%), Postives = 389/807 (48.20%), Query Frame = 1
Query: 133 FKMFWQLFFLYTV--VKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISK-CLTG---AFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLK--------IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDN-----PPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
F + W L F V + S LY V E Q PN+ IG+L Q S + ++LE G + VD K G+I+ T IDRE + C+ K C + + I ++ E +IE+ DINDN P F T+ + EN + F++P A DRD+E+ GV KY L + + ++ + P L V+G+LDRE S++ + A DGG + V ITD NDN PQ+ Y E+SE + VLQ+ A D D +G G+I + I + S + + ++ I S +++ G L + + VIA D +S+ T + +E+ D ND+ P +++ L+ I E+ V + V+D+D+G N+ +C + L S ++N +KK F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN PP FE EF +E+ + G ++ VIA D+DS N + YSII D + F I+ +G++ LDRE K+RYEF V A D G P+ + + I VLD NDN P+ + +SYSF ++E+ +G + D D G+N + V +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P + ++ ++ A S+V V+A D D+G N ++Y++ N + + SDG+I L K+L K RLVV+ D+G PS A ++I
Sbjct: 3 FSVGWFLLFALLVDSINSALGGILY-HVREEQPPNTLIGSLAA-DQGLPDSGHL-----YKLE------VGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSD----LGPNGEIEYTIHQAS---DPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDN--KKKYFLQTTTP---LDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEF-----AEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSP---VGMVTVLDMDKGENAQVQLSVEPDVGNFVVQ-NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKP--SNSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHI 773 HSP 2 Score: 131.724 bits (330), Expect = 1.188e-30 Identity = 130/461 (28.20%), Postives = 210/461 (45.55%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIST------SYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYF----GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYF 2466
+E++D ND+ P +L ++EN TD D N L+ S ++++ + N +K+ QL + L DRE Y + + D GTP+ SS ++ + I+D NDN P FE +SE++ +G+ + V A DSD PN I Y+I V + I + G I + LDRE ++F V A+D G + + + I V D NDN P + ++S + E + + SD+D G+N G F++R D V N+ K YF +D E++ V + +D+GNP ++T ++ ++V D NDN P F+ PL + ++ G V +V A D D G N ++Y++ + T+ LF I S G++ + LD + K V A D+G PS T T+ I+
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEAS--ALFSLQMANDRGEKLPQLIVLGNL--DRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAG---DSSVDNKKK--YFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFE----VEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVL 566 HSP 3 Score: 90.5077 bits (223), Expect = 6.214e-18 Identity = 143/581 (24.61%), Postives = 237/581 (40.79%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHG-----NNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLND--TNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS 1851
S E NSP+G ++Q + +++ + +++ ++ +++ G I V +DREEI +F ++I D + IE+ D NDN P+ + + I E++ + +L D+D + V + F+L G N +L+ LD E I+ + + A D G + V++TD NDN+P + + E +E KVL + A D D ++ + I +S + F I S + L + + V AAD S+ T + IK D ND+ P + S S + EN V +TV D D+G N++ S+ NFV ++NG + ++ FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + +V A+D D N + YSI G E F I+ +G+I L K L R+ + V+ D G+P+ + I ++ + VN+ I +S
Sbjct: 247 SYEAEVSENSPVG--YSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEIS---------SFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDAD--SGTNAELVYSIIADSSTRGL----FEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDVGNFV---------VQNGTGTILSSIS------FDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNSSFR--RLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGG-NPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRH---AIALVHIYVNETISNVS 783
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 268.47 bits (685), Expect = 2.891e-74 Identity = 236/794 (29.72%), Postives = 377/794 (47.48%), Query Frame = 1
Query: 145 WQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSA-IDREEI--CQ------PISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSL--------KIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
W + LY+ S S+ L E Q PN+ +G+L + + L + E Y R VD K GDI+ T IDRE + C+ P + + + + ++ E +IEI D NDN P F + IPEN + +S+PVA D+D+ G+ Y L S S ++ ++ D+ + P L V+G+LDRE +++ + DGG + + ITD NDN P++ Y E++E T + VLQ+ A D D GQ+ + + S N + ++ I + T I + K S+ + +S++ + + +KD ND+ P I++ L + E+ V + V+D+D+G N+ +C + L S S ++ ++K F + P D E+ Y +E++ D+G P +SS+ + + ++D NDN P F +E+ + G ++ V+A D+DS N + YSII D K F IN N G++ + LDRE K+RYEF VEA D G P+L + + + VLD NDN P+ + YSF ++E+ +G + D D G+N + V + IQ G I+ + DREK + +D G+PPR++ + I VLD NDN P T P +++ +L + + V +V A D D GLN ++Y++T N LF I S DG+I L K+ K RLVV+ D+G PS T ++I
Sbjct: 20 WTVLLLYSCGSSLASITYQL--REEQPPNTLVGSL--------AADQGLPDTGHLYKLEVGGPYLR----VDGKTGDIYTTDVPIDRETLKDCRNLFEGDPCFLEFEVSITDLMKGSGPRLIEGRIEIQDENDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKDAGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDD--LGANGQVTYSFHQPSPNVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASAS--DSTSKRKYFLQTTTP---LDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSP---VGMVTVIDADKGENAHVQLSVEPENGKFVIQ-NGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPSNSSYKFLQPL--TSPDTRVEKVDAEDIDTGLNAELVYSITGGN-PHGLFRISSTDGEITLAKEFTRKHNGLHRLVVKVSDKGKPSRHTTALVHI 785 HSP 2 Score: 133.65 bits (335), Expect = 3.717e-31 Identity = 135/467 (28.91%), Postives = 215/467 (46.04%), Query Frame = 1
Query: 1147 LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSM--YTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS------TSYSFKIVESWEREHKHFYIGKLNASDRDIGQN--------GTFRFRVRSRSTPIDIQVYNEGKIIYFGN----IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+EI+D ND+ P L I EN + D+D G N LN + D+M ++ + + +K+ QL + L DRE+ Y + + D GTP SS ++ I I+D NDN P FE ++E+ +G + V A D D N +TYS V+ I+HN G I + +DRE +F+V+A+DNG + + I V D NDN P I ++ I E + + SD+D G+N G F++RS S + K YF +D E++ + + + +D+GNP ++T ++ ++V D+NDN P F+ L ++ ++ G V +V ATD D G N ++Y++ + TK LF I + G++ + +LD + K VEA D+G PSL T T+ +R D
Sbjct: 131 IEIQDENDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKDAGSNGIADYKLNSGS----DAMNLFSLQVADNTDEKVPQLIVLGNL--DREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPNVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASA-----SDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYE----VDFAEENQPGDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRND 582 HSP 3 Score: 85.1149 bits (209), Expect = 2.727e-16 Identity = 127/525 (24.19%), Postives = 212/525 (40.38%), Query Frame = 1
Query: 340 RHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG-EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN--FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFET------EFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGD-----YEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNI 1839
+ L+ +D G I V ++DREE+ P+ K A N + + I + D NDN PS + ++ + E++ + +L D+D + V + + D + +L+ LD E IK + + A D G + V++TD+NDN P + Y + +E KVL + A D D ++ + I +S + + I T + +N + +KE V A G T+ + + D ND+ P ++ S + EN V +TV D D+G N+ S+ N FV ++NG + ++ FDREK S Y+ + D G P SS ITI + DENDN P+ +F S D ++ V A+D D+ N + YSI G + + T +G+I L K R+ + V+ D G+P+ + + + I V + N+
Sbjct: 302 QRLLHIDHNTGIIQVKGSVDREEV--PLLKFSVQARDNGPQAKSSKAM-VTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSA-SASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDAD--SGTNAELLYSIITDSAT-KGLFDINPNTGEVRVMN-QLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQLSVEPENGKFV---------IQNGTGTILSSIS------FDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPSNSSYKFLQPLTSPDTRVEK----VDAEDIDTGLNAELVYSITGGNPHGLFRISST-----DGEITLAKEFTRKHNGLHRLVVKVSDKGKPSRHTTALVHIFVNETISNV 794
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000016369.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:8904389:8910149:1 gene:ENSAMXG00000015901.2 transcript:ENSAMXT00000016369.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 235.728 bits (600), Expect = 1.939e-64 Identity = 213/697 (30.56%), Postives = 338/697 (48.49%), Query Frame = 1
Query: 115 ILFGLMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENY-FELIDHGNNIN-PYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL-NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDY--EVKETFGINHN---GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI----STSYSFKIVESWERE-HKHFYIGKLNASDRDIGQNGTFRFRVRSRS--TPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLD 2142
+ F L+ +FW+ F ++ +V E Q+ ++ +GN+ K + ++ LK + F++ S T G L V++ G + V IDREE+C+ S CL L + +I + +EI+DIND+ P F EK ++I EN + F L A+D DS V+ Y L E++ ++ D G + P+L + LDRE + HL A DGG Q G IIV++ DVNDN P + Y ++SE V+Q+NA D D + G++ F + + ++R+F + + + F++ + I A + + E +I ++I D ND+ P I+V S S+ I EN K V I+V+D D G+N + SCS+ D F L QK I+ L + L DREK S+Y + + D G P +SS + IT+F+SD NDN P F TF + E+ G + V A D D N +I+Y I+ D E K +N N G+I+ K D E Y+F + A D+G P+++ + + + +LD NDN+P I S++ S + VE R + + K+ A D DIG NG F ++ S + + Y G+I + +++ V DNGN +AT TV I++++
Sbjct: 9 VTFRLLL-LFWRGVF----------AQMRYTVLEGQRNDTVVGNIAKDLGIDQRT---LKERGFRIVS----TTGEPLFRVNRNDGVLHVNGKIDREEVCERSSSCLIN--LKIALENPLEIHYITVEIVDINDHAPIFPEKEKRLEISENAVAGARFQLQAARDADSGVNSVQLYKLSQN-----EHFRIDIKDRGEDGKIPFLILQKPLDRETSSKHKIHLTALDGGRPQKSGTMEIIVDVIDVNDNVPVFTKDAYSVKLSENAPIGTAVIQVNATDAD--EGTNGEVFFSFGHDVDSN--LLRLFDLDPVTGEIVVKGPIDFEQKYQYEIDIQASDKASAPLTTEKSIFIQIVDVNDNAPEIEVTSLSVAIAENSKPGTTVALISVSDLDSGMNGKVSCSVPEDIPF---------SLMQSSQKNIYSLTTTSSL--DREKTSQYDITLTAKDAGHPPLSSIKTITVFVSDVNDNSPEFSLNPYTFYVPENNVPGMSMFSVSAHDLDLDENGVISYHIVRDTAEENKHLSFLNINPETGEIYALKRFDFENIKSYQFNIVASDSGTPSMSSNVTVNVFILDQNDNVPVILYPVSSNGSAEGVEEISRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHSLFGLDRYT-GQIRTLRSFTETDEALHKLVILVKDNGNVSLSATATVIIKIVE 664 HSP 2 Score: 166.777 bits (421), Expect = 7.857e-42 Identity = 159/588 (27.04%), Postives = 275/588 (46.77%), Query Frame = 1
Query: 817 IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADGEGRSNETTIEL--EIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLN---DTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-----LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY------NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLN---AHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN-QNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSN 2496
I VEI D+ND+ P + R EISE QL A D Q+ +K+S+N +++ + ++ I +L + L +K I + A DG T+E+ ++ D ND+ PV + S+K+ EN V ++ TD D+G N E S D+N + ++F L+ + G D E+ +Y +++ +D + +++ + I I I D NDN P E + +I+E++K G + ++ D DS N ++ S+ D F + + Q ++ + LDRE +Y+ T+ AKD G P L+ I + V DVNDN PE S + Y+F + E+ F + +A D D+ +NG + + + + + G+I D E + + D+G P ++ TV++ +LD NDN P YP+ + A I+ ++ AG +V +V+A D D G NG ++++L +H+ LF + + GQI + + +LV+ +D G SLSAT T+ I+ +P+++F S+
Sbjct: 113 ITVEIVDINDHAPIFPEKEKRLEISENAVAGARFQLQAARDADSGVNSVQL-YKLSQN-EHFRIDIKDRGEDGKIPFLILQKPLDRETSSKHKIHLTALDGGRPQKSGTMEIIVDVIDVNDNVPVFTKDAYSVKLSENAPIGTAVIQVNATDADEGTNGEVFFSFGHDVDSNLL----------------RLFDLDPVTGEIVVKGPIDFEQKYQYEIDIQASDKASAPLTTEKSIFIQIVDVNDNAPEIEVTSLSVAIAENSKPGTTVALISVSDLDSGMNGKVSCSVPEDIP----FSLMQSSQKNIYSLTTTSSLDREKTSQYDITLTAKDAGHPPLSSIKTITVFVSDVNDNSPEFSLNPYTFYVPENNVPGMSMFSV---SAHDLDLDENGVISYHIVRDTAEENKHLSFLNINPETGEIYALKRFDFENIKSYQFNIVASDSGTPSMSSNVTVNVFILDQNDNVPVILYPVSSNGSAEGVEEISRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHS--LFGLDRYTGQIRTLRSFTETDEALHKLVILVKDNGNVSLSATATVIIKIVEPKEAFAASD 673 HSP 3 Score: 53.1434 bits (126), Expect = 1.844e-6 Identity = 61/215 (28.37%), Postives = 105/215 (48.84%), Query Frame = 1
Query: 1678 FGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRII---VLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV-RSRSTPIDIQVYNE-GKIIYF---GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
F +N N G +H+N +DRE + E + N + L + +I I ++D+ND+ P K +E E A D D G N +++ ++ IDI+ E GKI + +DRE K + + +D G P ++ T + ++V+DVNDN P FT +A++ + ++++ G+ V +V ATD D G NG + ++
Sbjct: 69 FRVNRNDGVLHVNGKIDRE--EVCERSSSCLINLKIALENPLEIHYITVEIVDINDHAPIFPEKE--KRLEISENAVAGARFQLQAARDADSGVNSVQLYKLSQNEHFRIDIKDRGEDGKIPFLILQKPLDRETSSKHKIHLTALDGGRPQKSGTMEIIVDVIDVNDNVPVFTK---DAYS-VKLSENAPIGTAVIQVNATDADEGTNGEVFFSF 275
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000035285.1 (pep primary_assembly:Astyanax_mexicanus-2.0:8:8923404:8955697:1 gene:ENSAMXG00000041384.1 transcript:ENSAMXT00000035285.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 228.024 bits (580), Expect = 1.567e-61 Identity = 217/695 (31.22%), Postives = 338/695 (48.63%), Query Frame = 1
Query: 124 GLMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENY-FELIDHGNNIN-PYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISEN-SQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETT---IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL-NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGD--YEVKETFGINHN---GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI----STSYSFKIVESWERE-HKHFYIGKLNASDRDIGQNGTFRFRVRSRS--TPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLD 2142
GL+F +FW+ F ++ SV E Q+ + +GN+ K + ++ LK + F++ S T G L V++ G + V IDREE+C+ S CL L + +I + +EI+DIND+ P F EK ++I EN F L A+D DS V+ Y L E++ E+ D G + P+L + LDRE + L A DGG Q G IIV++ D+NDN P + Y ++SE KV+Q+NA D D+ G++ + ++ ++N + + +T I+ + F++ + I A + + TT I ++I D ND+ P I+V S S+ + EN S V I+V+D D G+N + SCS+ D F L S Q+ I+ L + L DREK S+Y + I D G P +SS + +T+F+SD NDN P F TF + E+ G + V A D D N II+Y I D E K + +N N G I+ K D E Y+F + A D+G P+L+ + + + +LD NDN+P I S++ S + VE R + + K+ A D DIG NG F ++ S + + Y G+I + +++ V DNGN +AT TV I++++
Sbjct: 17 GLLF-LFWRGVF----------AQIRYSVLEEQRNGTVVGNIAKDLGIDQRT---LKERGFRIVS----TTGETLFRVNRNDGVLHVNGKIDREEVCERSSSCLIN--LKIALENPLEIHYVTVEIVDINDHPPIFSEKEKRLEISENAIAGVRFQLQGARDADSGVNSVQMYKLSQN-----EHFRIEVRDRGEDGKMPFLILQKSLDRETCARHKLLLTALDGGRPQKSGTMEIIVDVIDINDNAPVFTKDTYSAKLSENAPIGTKVIQVNATDLDNGPN--GEVFYIFGQDVNRNLRRVFDLDPVTGEIV---VKGPIDFEQKYQYEIDIQASDKALAPLTTDKIILIQIVDVNDNAPEIEVTSLSIAVPENSHSGTTVALISVSDVDSGMNGKVSCSVPEDIPFSLLQS---------SQENIYSLVTKSSL--DREKTSQYDITFIAKDAGHPPLSSIKTLTVFVSDVNDNSPEFSLNPYTFYVPENNVPGMSMFSVSAHDLDLDENAIISYHIWRDPAQENKHSSFLNINPETGAIYALKSFDFESTKSYQFYIVASDSGTPSLSSNVTVNVFILDQNDNVPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHSLFGLDRYT-GQIRTLRSFTETDEALHKLVILVKDNGNVSLSATATVIIKIVE 669 HSP 2 Score: 152.91 bits (385), Expect = 2.183e-37 Identity = 156/590 (26.44%), Postives = 269/590 (45.59%), Query Frame = 1
Query: 817 IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADGEGRSNETTIEL--EIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE-FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKI-----LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV-------RSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLN---AHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN-QNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENS 2505
+ VEI D+ND+ P + R EISE QL D Q+ +K+S+N +++ + VR + +L + +L + +++ A DG T+E+ ++ D ND+ PV + S K+ EN V ++ TD D G N E F D N +++F L+ + G D E+ +Y +++ +D +++ +II I I D NDN P E + ++ E++ G + ++ D DS N ++ S+ D F + + Q ++ + LDRE +Y+ T AKD G P L+ + + V DVNDN PE S + Y+F + E+ F + +A D D+ +N + + S+ ++I G I + D E + D+G P ++ TV++ +LD NDN P YP+ + A I ++ AG +V +V+A D D G NG ++++L +H+ LF + + GQI + + +LV+ +D G SLSAT T+ I+ +P+++F S+ S
Sbjct: 118 VTVEIVDINDHPPIFSEKEKRLEISENAIAGVRFQLQGARDADSGVNSVQM-YKLSQN-EHFRIEVRDRGEDGKMPFLILQKSLDRETCARHKLLLTALDGGRPQKSGTMEIIVDVIDINDNAPVFTKDTYSAKLSENAPIGTKVIQVNATDLDNGPNGEVFYIFGQDVN--------------RNLRRVFDLDPVTGEIVVKGPIDFEQKYQYEIDIQASDKALAPLTTDKIILIQIVDVNDNAPEIEVTSLSIAVPENSHSGTTVALISVSDVDSGMNGKVSCSVPEDIP----FSLLQSSQENIYSLVTKSSLDREKTSQYDITFIAKDAGHPPLSSIKTLTVFVSDVNDNSPEFSLNPYTFYVPENNVPGMSMFSV---SAHDLDLDENAIISYHIWRDPAQENKHSSFLNINP-ETGAIYALKSFDFESTKSYQFYIVASDSGTPSLSSNVTVNVFILDQNDNVPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHS--LFGLDRYTGQIRTLRSFTETDEALHKLVILVKDNGNVSLSATATVIIKIVEPKEAFAASDVKS 681 HSP 3 Score: 56.6102 bits (135), Expect = 1.633e-7 Identity = 62/221 (28.05%), Postives = 101/221 (45.70%), Query Frame = 1
Query: 1678 FGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRII---VLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIG----------QNGTFRFRVRSRSTPIDIQVYNEGKIIYF---GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIY 2289
F +N N G +H+N +DRE + E + N + L + +I + ++D+ND+ P S K +E E A D D G QN FR VR R +GK+ + ++DRE + +L+ +D G P ++ T + ++V+D+NDN P FT +A ++++ G+ V +V ATD D G NG + Y
Sbjct: 74 FRVNRNDGVLHVNGKIDRE--EVCERSSSCLINLKIALENPLEIHYVTVEIVDINDHPPIFSEKE--KRLEISENAIAGVRFQLQGARDADSGVNSVQMYKLSQNEHFRIEVRDRG--------EDGKMPFLILQKSLDRETCARHKLLLTALDGGRPQKSGTMEIIVDVIDINDNAPVFTKDTYSA----KLSENAPIGTKVIQVNATDLDNGPNGEVFY 278
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 202.216 bits (513), Expect = 1.378e-53 Identity = 213/754 (28.25%), Postives = 331/754 (43.90%), Query Frame = 1
Query: 346 LISVDQKKGDIWVTSAIDREEIC--QPISKCLTGAFLNYIIFA---------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXE-NYFELIDHGNNI---------------NPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRK-EISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGE--GRSNETTIELEIKDCNDHRPVIKVHS--------SSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF------ETEFKTFSIS--EDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESW---EREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE---GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVG-EVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQG 2421
L V++ G++ V +DRE +C +P C + F++ + A + ++ ++Q+ + DIND+ P+F+ + I E+ A LP A D D+ ++ Y + + S + F L++ ++ L + LDRE + S+E L+ DGG + G + + + D NDN P +V P R I+E V+QL A D D F S + + + T + N L +VV+A DG RS T+ +E+ D ND+ PV +V + +KI EN S V I+V+D D G + L L SP K F L + D E+A +Y+V V+ D GTP +S + I + D NDN P F E + + +S E+ G + ++A D+DS PN IT+++ G V E F +N GQ+ L LDRE + RYE +VEA D G P +R+ VLD NDN P + S S + + E Y+G ++ SD D G N + + P I + G + +DRE + ++ V +D+G P +A+ V I V D NDN P T P N + ++ AG +VG V A D D G NG +Y + N K +F + +D G + L + + + + RLVV RD+G
Sbjct: 73 LCIVNELSGELSVALRLDREALCMEEP-DACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAEL----ASP-----NKVQFLLKTT--RLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTN-DTWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGN-PKGIFLLNADSGALSLARTVSSLDEGLHRLVVRVRDRG 812 HSP 2 Score: 117.087 bits (292), Expect = 8.881e-27 Identity = 135/507 (26.63%), Postives = 213/507 (42.01%), Query Frame = 1
Query: 1096 VVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS----EFSCSLNDTNFVSLDSMYTSPLENG------------GQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF-ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKI-----LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIP---------EISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGN----IDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLL----NAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLT---NQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
V A G+G SN ++L ++D NDH P + ++ I E+E V D D G NS S + D + S+ S ++ G + + +L DRE Y + + D G P +S S ++TI + D NDN P F + + I+E +K+G + + A D D+ PN I YS T H +G L + LDRE + V A+D G+ + + S + + + D NDN P E KIVE+ I + SD D+G +GT R+ P ++ + K+ + +D E+ + +V V D G P + + I V+D+NDN P F P A +++ ++ AG++V + ATD D G NG+I + L+ +LFS+ GQ+ L LD + + L VEA D G+P A + + D
Sbjct: 113 VAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELRE----QLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLI---SVSDPDLGSSGTVDVRLE---FPTGAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDEND 609
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 187.963 bits (476), Expect = 6.480e-49 Identity = 195/721 (27.05%), Postives = 313/721 (43.41%), Query Frame = 1
Query: 301 SFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEIC---QPISKCLTGAFLNYIIFADHQIF---ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFEL----IDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV---RIFYITESILYLNIGALKSFKENKASIVVIAADGEG---------------RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSI--PGLY-------FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
++++ K+ L+ V+ + G+++ +DRE +C P +C + + F E++I + DINDN P+F T+ +PEN F + A D DSE GV++Y L + + FEL +G + PYL V LDRE + +E +L A DGG + G + + +TD NDN+P + EI E V+QL+A D+D ++ +++ ++ R+F + ++ + + L + +E+ ++I A +G N+ + +EI+D ++ + + I E + V ITV+D D G N +C + + FQL + P Y D E + Y V++ D G ++S + +TI + D NDN P F S+ E+ IG + V A D D N + Y + D F ++ G I L + LDRE K Y FT+ AKD G P L + + + VLDVNDN P S + + F + E+ KH +G + +D D G+NG R + + E +I DRE+ + V D G P R++T V I V+D+NDN P P N Y + G+IV EV A D D +N + Y++ N +LF I
Sbjct: 70 TYKVMLSKAEDAAPPLVRVNPRTGELFAAGRKMDREALCGGQDPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATV-SAFELSVTETANGEKV-PYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSN--AEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRD------IVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVP------------------FQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPD--APTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVP---KHSTVGMVTVADSDEGENGRVRLSILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPSNT-TYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGN-PHNLFHI 755 HSP 2 Score: 83.9593 bits (206), Expect = 1.205e-16 Identity = 108/478 (22.59%), Postives = 190/478 (39.75%), Query Frame = 1
Query: 1141 IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI-------IGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNG----------------EPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY---NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
+ + ++D ND+ P ++ + EN + D D N L ++ ++ + S E +K+ L L DRE+ Y + + D G+P S S ++ I ++D NDN P F+ I E++ +G + + A D D+ N + Y + K F ++ N G + +N +L+RE Y + A D G + + + +IR IV VN ++ E H + + + SD DIG NG + + P ++ N+ + +D E ++ V + D G + T +V I++LD NDN P FT P +++ ++ G + V ATD D N ++Y L T +F + + II + + K + + A+DQG P L T+ + D+ R
Sbjct: 139 VRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSL--DREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVN------------GVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYK----VSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPT--MFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPR 596
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 172.94 bits (437), Expect = 9.721e-44 Identity = 204/768 (26.56%), Postives = 324/768 (42.19%), Query Frame = 1
Query: 340 RHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQ---------IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISE--------CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV-----RIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQK-KIFQLNSIPGLY-FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKET-FGIN-HNGQIHLNKILDREVKDR------YEFTVEAKDNGEPN-LNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRY---------FKPRDSFDRSNEN 2502
R + +D G + ++DREE+ + Y + Q ++ + + D+NDN P F P + I EN + + A D D G +Y L + ++ F++ N + + LDRE ++ + A DGG + + IV IT D D P + Y + E + A L LNA + + I Q + RIF A+ ++ + V+A G G + E ++ + + D N+H PV S + I E+E + TD+D G N E + + NGG+K IF + Y DRE YS+ V D G +SSS + + + D NDN P F + F E+ ++G +G V A D+D+ N +TYS +E + F ++ G+I ++ DRE R + F+V A D G P L D +++ V DVNDN P+ + S Y + ES + ++ ASD D G NG R+ + + V + G+I G++DRE+ ++V D+G P A+ TV ++VLD NDN P+FT LL+ ++ + G ++ + A+DED G +G + Y + N T F+I +S G + L ++LD + + RL V A D G P S+ T L + F P D F EN
Sbjct: 494 REMFRLDSLTGKVTTLKSLDREELEE------------YPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAAR----FQV----NAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNA-----------NVTYLIVSGDQRGSFSIEWSGGRIF---------TANAIDREEQAFYQLRVVANSG-GVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEG--------------NGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYS----FEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLL---RVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLS----VDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGN-THATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMEN 1194 HSP 2 Score: 171.014 bits (432), Expect = 3.533e-43 Identity = 194/739 (26.25%), Postives = 320/739 (43.30%), Query Frame = 1
Query: 250 IKLIQNQT---KSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDI------WVTSAIDREEICQPI--SKCLT-------GAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE------CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIA--ADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNG---TPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKET--------FGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIST-SYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE-GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQ 2346
I L+Q QT S+ + E E + L+ V + G I W S D C I S L+ G+F+ + + +Q+ +I + D+NDN P F E +++ EN A D D + + Y + S S E F ++D + + LR LDRE S+ + ASDG + R+ V + D NDN+P++ Y +++E TT A + + A D D G++ + ++ S++ + F + LN+ +E++A V+ A DG G + + + + D ND+ P ++ S + ++ E+ + RI+ TD+D+G+N+E S++ S D + N GQ + + DRE+ S Y++ V +D +SS+ +++ ++D NDN P F T ++ ED+ +G + V A D DS N+ + Y++ D E F +N G++ L + LDRE + Y TV A D G P L + + + V D NDN P Y I E E + +L+A D D G NG R+ + S D ++ G + +DRE+ ++ V D G P R+ T +V + + DVND P F H N ++ +V A D+D G +G + Y N FS+ DG
Sbjct: 1409 INLLQGQTIPMPSSYLFLRHHLDWEPEGQLVFFTLLLGVTRGHGVINPLDAPWRVS-FDLTARCMFIVFSSLLSSLRDNGAGSFIRPPMSSFNQV---EISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGS----EGAF-VVDAASGV---LRASRRLDREERASYLLTVRASDGT-HATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPF--GEVTYALAP-SEDSDWADGAFGLHPVTGALNV-TRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSIS-----SGDPEGRFAVGNDGQLSVARA-------LDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAF-TSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAED---EPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENT---QGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGG-AFSVSPDGH 2110 HSP 3 Score: 159.844 bits (403), Expect = 1.213e-39 Identity = 167/658 (25.38%), Postives = 284/658 (43.16%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSF-QPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELI---DHGNNINP---------YLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKV-----HSSSLKIKENEKSKILVTRITVTDEDQ-GINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS--IPGLY-------FDREKASRYSVEVICNDNGTPTM-SSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-----GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--------GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTK 2316
E+++ + D+NDN PSF +P + E+ A + L A DRD GV + ++++ + G + P +L G LDRE S+ + A DGG + G+ ++ V + D NDN P + YR ++E + L+ P + + + Q + R Y ++ + AADG S T +++ D ND+ P I+ + S + E+ + +TVTD D N E S S + G ++ F L++ +PGL DRE+ Y++ ++ +DNG P S++ + ++++D ND+ P F ++SE A G + V A D+DS N + YSI+ G + V E+ G+ + + +DREV + A+D G + + +LDVND P + T Y + + E ++ ++A+D D+G+NGT R+ P Y E GK+ ++DRE++++ ++V D G+PP +T V + V D+NDN P F YP+ + +I ++ G+ V V ATD D G NG++ Y LT + +
Sbjct: 8 EVRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVN------------HHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDLLHRGRGPLAVPFDPKTGMVSTRQPLDFEARRQY---------------------TLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVS----------------IVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGL-----VTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKY---VATAVENSLPGLFVVSVSAADSDLGENGTVRYNF----DPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVF-YPV---QYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAAR 600 HSP 4 Score: 157.532 bits (397), Expect = 5.917e-39 Identity = 172/681 (25.26%), Postives = 281/681 (41.26%), Query Frame = 1
Query: 340 RHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQ--IFELQIEII--DINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPY-------LRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR----SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTP-----IDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPP----RTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN 2301
R S++ G I+ +AIDREE AF + A+ E + ++ D+N++ P F + I E+ +S F A D+DS K G E +E I GN + L V +LDRE + + + A D G + V +T DVNDN P + Y E E L Q D G + + + N+E+ I ++ ++ S V+A DG GR + T+++ ++D ND+ P + E+ + + R+T +D D+G+N ++N+ N +T G +I L S+ DRE+ + Y++ V D+GT +++S + + + DENDNPP F + E ++G + + A D D+ P+ + Y+I+ TF I+ + G + L + LD E + Y V A+D G P + + + + V D NDN P F + E + + A D D NG + + + P ID + G+I IDRE + + + P R+A V + V D NDN P+F P + L AAGS+VG ++A+D D N ++ Y +T
Sbjct: 701 RGSFSIEWSGGRIFTANAIDREE----------QAFYQLRVVANSGGVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNG--------------EVKYE-IGEGNGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCE-EQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDG-GRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGN---EGGKFTVDASTG---QITLLGSL-----DREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAG-NTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASI--MENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPE---SGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLR----AAAGSVVGTLQASDPDEAENAAVRYAVTG 1333 HSP 5 Score: 153.295 bits (386), Expect = 1.176e-37 Identity = 199/754 (26.39%), Postives = 316/754 (41.91%), Query Frame = 1
Query: 352 SVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFE-------LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLP-------VAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG----GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDP-QTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKA--SIVVIAADG---EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNG--TFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXX------XXXNGNP-PRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMN 2511
SVD+ G + +DRE + LN I A Q + L + ++D+ND P F + VA + E SLP A D D + G +Y + Y F L +++ + + LDRE ++ + + A D G G+ K ++V D+NDN P + + Y I E E + DP + G +R++++ + + + + L+ +E +A + V A DG RS + + + D D P S + EN LV ++ + D N + VS D + +E G +IF N+I DRE+ + Y + V+ N G +S +++ + D N++ P F+ SI+ED + V A D DS N + Y I G+ E FGI +GQ+++ LDRE ++ Y TV A D G L+ S + + VLDVNDN P S+SY F E E +G + A+D D G NG T+ F + +D + G+I DRE + + D G P P TV + V DVNDN P+F + A ++++ + + + V A+D D G+NG++ Y + N S GQI L LD + LVV A D GT L+A+ T+ ++ D+ R E+ ++
Sbjct: 390 SVDESTGLVTTDGKVDRE--------VASSVVLN--ISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKY-------VATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRL----DSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVV--GDLNDNHPVFYPVQYFASILE--NEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLD-------REERAVYQLQVTALDGGHLRARS-PAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYL-------IVSGDQRGSFSIEWSG-GRIFTANAI-----DREEQAFYQLRVVANSGGVAGEAS---VSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEI-GEGNGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGS---LVGAVQATDADAGSNGGVTYSFEKPQVNFELDSET---GRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQA----SVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLS 1083 HSP 6 Score: 147.902 bits (372), Expect = 5.646e-36 Identity = 175/657 (26.64%), Postives = 282/657 (42.92%), Query Frame = 1
Query: 376 IWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIG--GQIRFKISEN-SQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD-GEGRSNETT-IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYL-NITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+ V S +DRE I P+ A N A L + + D+ND+ P F + E S A D DS G+ SI S +F +D + + G +DRE S ++ A D G + V + DVND P + Y E + V+ ++A D D +G G +R+ + Y + R+ +T + L +L + + +VV A D G T + + + D ND+ PV I ENE VT +T TD D+G N L G FQ+N++ G + DRE+ + Y ++V D G S I+TI ++D D PP F + +F + E+ G +G V A D + N +TY I+ GD + +F I G+I +DRE + Y+ V A G + + ++V DVN++ P SY I E + F + A+D+D G+NG ++ + + ++ +G++ +DRE ++ + V +D G P +++ TV++ VLDVNDN+ PL N+ +Y+ + ++ GS+VG V+ATD D G NG + Y+
Sbjct: 292 LKVASQLDRERI--PMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADS---GLNAKLRYSIVSGNDLGWFS-VDESTGL---VTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSD----LGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLK--SLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQL-----------------TAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNAN--VTYLIVSGDQ--RGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSV---RATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNK-----PLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSF 901 HSP 7 Score: 137.502 bits (345), Expect = 7.057e-33 Identity = 158/646 (24.46%), Postives = 254/646 (39.32%), Query Frame = 1
Query: 184 FSV-KLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPV-----AKDRDSEKYG-VXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR------SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-----GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDRE 2049
F+V ++ L VEEN I L +Q ++ L T S SE + VD G + + +DREE S LT + D + L + + D NDN P F + + E+ A + + V A D DS +G V S S + F L + + L V LDRE+ + A+DGGG R+ V + D NDN P E+ E +L+++A D D + + ++ F IS F + AL +++ ++VV +D R S+ + L + D ND+ P S+L +++ ++ T + D D G NS +L F LN++ G DRE Y++ V+ D G P ++S+ + + + D NDN P F +I+ED G E+ + A D D N + Y I GD+ + G + + + LDRE YE V A+D G P +D+ +R+ + DVND P S + + + I ++ A D D+G +G + + V +G + ++DRE
Sbjct: 1516 FAVPEMELEVEENTGEGEVIFTLSATDADQGQNA--LVTYSVLSGSEGA-------FVVDAASGVLRASRRLDREERA---SYLLTVRASDGTHATDAR---LSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGL----HPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDD--EGVNAELEFSISSGDPEGR-----FAVGNDGQLSVARALDRERQSFYNLVVRVSD-RARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVAT-VQAVDPDSGRNSYVEYALATDGEEGGGGAGAG-------PGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGT-----LAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLS-PYTVHARENTQGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGGAFSVSPDGHVHLLRSLDRE 2120 HSP 8 Score: 133.265 bits (334), Expect = 1.605e-31 Identity = 171/676 (25.30%), Postives = 283/676 (41.86%), Query Frame = 1
Query: 493 IEIIDINDNFPSFQ-----PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG---GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVV-IAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIST-SYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
I+++D+NDN P+ + P ++ + E+ A + +L D DS SI +F L G L+V LDRE I + + ASD G ++V + DVND+ P++ Y +SE V + A D D + ++R+ I S N + F + ES + K +E +S+V+ I+A +G ++ T++ + + D ND P+ EN + V ++ D D G N + + + + Y +++F+L+S+ G DRE+ Y + V D G+P + S+ +T+ + D NDN P F SI E+ G + V A D D N + Y + + F +N G + LDRE + Y+ V A D G + I V D D P + YSF + +E +G ++AS D+ N T+ + I+ ++ G+I IDRE+ + V G +V + V DVN++ P F A ++I +D S V+ATD+D G NG + Y + N + F I DGQ+ ++ +LD + + L V A D G LS++ T+ +
Sbjct: 213 IQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPT--ANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDAD--SGLNAKLRYSIVSGNDLGW------FSVDESTGLVTTDG-KVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDP----DMPAQY---------REMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAAR--FQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVV---FENVAPGTLVGSVSASTLDLNANVTYLIVSGDQRGSFSIE-WSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFD----RASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEK-FGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNV 850 HSP 9 Score: 131.339 bits (329), Expect = 6.349e-31 Identity = 131/513 (25.54%), Postives = 230/513 (44.83%), Query Frame = 1
Query: 997 NYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHE-----IGIVIAKDSDSSPNNIITYSIIGDYE---VKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNG-NPPRTATTTVHIEVL--DVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN--------QNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++++ R +I S L L S ++N A + S+ +E+ ++D ND+ PV V L+++EN ++ ++ TD DQG N+ + S+ G + F +++ G+ DRE+ + Y + V +D T ++ +++ + D NDN P F +F ++EDA + IG V+A D+DS P +TY++ + FG++ G +++ + LDRE + Y A D G L + ++ + VLD NDN P + E E + +++A+D D G N F + S V N+G++ +DRE+ +++V V D +PP ++ V + ++ DVNDN P FT P +D G++V V+A D D G N + Y L F++ + G++ L ++LD + + L V A D+G P L++T TL +
Sbjct: 1464 SFDLTARCMFIVFSSL------LSSLRDNGAGSFIRPP----MSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLS-----------------GSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDG---THATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGG--GLAATARLYVNVLDANDNAPSVQNDS--LAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSP-----RSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAV 1937 HSP 10 Score: 129.413 bits (324), Expect = 2.641e-30 Identity = 136/575 (23.65%), Postives = 244/575 (42.43%), Query Frame = 1
Query: 814 RIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVL-QLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKAS--IVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKEN-----EKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGE---PNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE----------GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
++ + + DVNDN P + E+ E T E +V+ L+A D D Q + + + S+ ++ + + L+ +E +AS + V A+DG + + + + ++D ND+ P H+ S + E+ + ++ ++ + D D G E + +L + DS + F L+ + G DRE + Y + D G ++++ + + + D NDN P + + + EDA G + + A D D N + +SI GD E + F + ++GQ+ + + LDRE + Y V D L+ + ++ +I+ DVNDN P ++ S + E + + A D D G+N + + + G++ +DRE + V +D G PP T+T T+ + V D NDN P+F A I +D G+ V + A D D G NG + Y++ + + T D G + + + LD + L V ARD G P+ S T ++ +
Sbjct: 1501 QVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQN--ALVTYSVLSGSEGAFVVDAASGVLRASRRLD-------REERASYLLTVRASDGT-HATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSE----DSDWA--------DGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGR--FAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRS---ALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAA----IAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRV 2042 HSP 11 Score: 128.257 bits (321), Expect = 5.076e-30 Identity = 150/586 (25.60%), Postives = 243/586 (41.47%), Query Frame = 1
Query: 370 GDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENI------KSFEFHLYASDGGGN---QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTE-AKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYF-----DREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDR-YEFTVEAKDNGEPNLNDSCKIR---IIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGN-IDRE 2049
G ++V +DRE + LT + ++ + + + ++D+NDN P F E S A D D+ G + S + FEL I LRV DRE + SF F + A+DGG Q + + V + DVNDN PQ+ Y+ +SE + ++L++ A D D + + G +R+ I+E ++ + F + S + + +E + +V++A G S T+ +++ D ND+ P + S L + E +++ L+ +T +DED G + + ++ G F ++ G F D E Y + V D G P SS+ I+ + + D NDNPP F SI E+ IG + V A+D D+ N + YSI + F I+ +G+I +DREV +E TV A D P ++ ++V D NDN P T + I+ R +G L ASD D +N R+ V I ++ II +DRE
Sbjct: 812 GQLYVRYELDRETREE---YSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNG-----GVTYSFEKPQVNFELDSETGRIA-SLRV---FDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVD--EGVNGALRYAINEGNEGGK-----FTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPP--RFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAI----------------VAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTA--ILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELDRE 1358 HSP 12 Score: 126.331 bits (316), Expect = 1.890e-29 Identity = 136/552 (24.64%), Postives = 241/552 (43.66%), Query Frame = 1
Query: 739 LDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP--QWVGLP---YRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGE---GRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL---NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDY--EVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDG 2343
LD E + + L A+DGG G+ ++++ DVNDN P ++V LP + E V L D T G++ I ++ ++ + + L + ++ ++A+D RS ++ + + D NDH P + + + + E + V +T D D G+N++ S+ ND + S+D T + G+ DRE AS + + D G ++ +T+ + D ND PP F + E++ G + V A DSD N + Y+ D + +E F ++ G++ K LDRE + Y V+A+D G P L + K+ ++V D+NDN P F + E E + + A+D D G NGT R+++ + QV G + ++DRE+ + V +D G+ + V I V D D P F + ++++ + +++A G++VG V A+ D LN ++ Y + + + + FSI+ G
Sbjct: 183 LDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDES-TGLVTTDGK-------------VDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASI--LENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDA-ARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFAR---DDYSFV-VFENVAPGTLVGSVSASTLD--LNANVTYLIVSGDQ-RGSFSIEWSG 710 HSP 13 Score: 107.071 bits (266), Expect = 1.805e-23 Identity = 143/578 (24.74%), Postives = 238/578 (41.18%), Query Frame = 1
Query: 808 KCRIIVEITDVNDNTPQWVGLPYRKEIS---ECTTEAKVLQLNAQDKD-DPQTIGGQIRFKISENSQNYEMIVRIFYITESILYL-NIGALKSFKENKASIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPP-----HFETEFKTFSISEDAKIGHEIGIVIAKDSDS-SPNNIITYSIIGDYE----VKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEP-NLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY----NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFT---YPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQ--NHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ R++V DVNDN P + P E++ + +VL A D+D P + +KI ++ ++ + L+L G L ++ V A DG R + + ++D ND+ P + + + E+ S +L D L PL K +++ L F+ + +Y++ + D G P +S I + D NDN P + ++ S+ E A G +V D+DS + N ++ SI+G E V G+ + + LDRE Y T+ A DNG+P + + + + V DVND+ P + S E Y+ + A D D G N R+ + S + D+ + + G + G +DRE + + + D G P+TA T++ + +LDVND P FT Y N L G V V A D D G NG++ YN +++F + S G++ K LD + LVV+A+D+G+P L +T + +
Sbjct: 8 EVRVVV--GDVNDNAPSFPE-PGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHA-YKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAED--------------------SPVGAALRD-----LLHRGRGPLAVPFDPKTGMVSTRQPLDFEARR--QYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAA--ALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGN---DLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSL-------PGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTV 542 HSP 14 Score: 93.9745 bits (232), Expect = 1.382e-19 Identity = 120/506 (23.72%), Postives = 197/506 (38.93%), Query Frame = 1
Query: 328 NTYGRHLISVDQKKGDIWVTSAIDRE-EICQPI-SKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN-----QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI--GALKSFKE------NKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGI--VIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKD 1770
+G H ++ G + VT +DRE C + ++ G L L + ++D NDN PS Q D ++PE+ + A D D GV SISS E F + + G L V LDRE + + SD + R+ + +TDVNDN P + + A V + A D D G+ + + + E LN G ++ +E ++ V+A D +GR ++ T+ + + D ND+ P I E+E V R++ D D+G N E + +G F+L+ + G DRE+ + Y + V D G P S + + + +SD ND P F+ T E+ + G + I V+A+D D + +TY+ F ++ +G +HL + LDRE + ++ + A D
Sbjct: 1672 GAFGLHPVT-----GALNVTRPLDRESRACYVLRARATDGGGL-------AATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDE---GVNAELEFSISSGDPEGRFAVGNDGQ-----LSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDS-----GRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVD-KGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDI----------------ASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQ-GPPVLILQVVARDDDLGSSGQVTYAAA-GGNDGGAFSVSPDGHVHLLRSLDREAQPQHVLIITATD 2133
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.696 bits (413), Expect = 8.061e-41 Identity = 167/577 (28.94%), Postives = 270/577 (46.79%), Query Frame = 1
Query: 775 LYASDGGGNQ-GKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKEN-KASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDS--CKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFG-NIDREX------XXXXXXXXXXXXNGNPPRTATTTVHIEVL--DVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
L+A++ G G R+ + + + NDN P + Y + E T V+Q+ A D D + GQ+ + S++S F + + +++ A F+ + ++ V+A DG G+ + + + D ND+ PV + S +EN+ S V R+ TDED N++ + S+ T S S Y S +GG + + L +++ S+ ++ D G+P ++S+ + + DENDN P F+ + +I E+ G + V A D D SP S+I E F IN +G I +LDRE +Y V A D G+ N + + I +LDVNDN P Y+ IVE+ F + +A+D D+ +NGT + + + I + GKI G +DRE ++V D G+PPR AT + + VL DVNDN P F + L + + + A S + +V ATD D G NG++ Y++T D + G I +LD + +L + A D+GTP+LS+TTTL +
Sbjct: 1 LFANETSGEHWGSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLD--AGVFGQVSYHFSDDSDK-------FSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPT---SAYSSYFSITVSGGYGVVTLARA---LDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSP-EYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTV---SAADPDLNENGTLVYAIDPPNPFYRINAAS-GKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSF----VGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSL 553 HSP 2 Score: 155.992 bits (393), Expect = 1.954e-38 Identity = 201/756 (26.59%), Postives = 321/756 (42.46%), Query Frame = 1
Query: 217 NQKPNSPIGNL----IKLIQNQTKSTEILKTKSFQLESEKSNTYGRHL------ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFAD----HQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSL-PVAKDR--DSEKYGVXXXXXXXXXXXXXENYFEL-IDHGNNINPYLRVIGDLDRENIK--SFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKD-DPQTIGGQIRFKIS-ENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG----EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTN-FVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREK------ASRYSVEVICNDNGTPT--MSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG-----DYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYS-FKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNG--NPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDG 2343
N+ N PI +L + + +N T T +++ + L++ H S+D G I V +A+D E T F ++ D ++I ++D+NDN P FQ D AR ++ SL PV + R D + + + +S Y +YF + + G + R LD E I + + A DGG IVE+ D NDN+P + Y I E A VL +NA D D P+ GQ+ S E S + + R IT + L L ++ ++V A DG + ++ T+ + + D ND+ P + ++ I EN + ++ D D N +++ N F + N KI GL DRE AS S+ V D G+P ++S +T+ + D NDN P F + E + V A D D N +TYS+ D+++ G+ I LDRE Y+ + A D G P L+ + + ++VLDVNDN P + S ++ES R+ + LN +D D G N F + + V + +G + ++DRE ++++ IDNG RT TTT+ + VLDVNDNRP F L +++ +++ G+I+ +V+ATD D G+NG + Y + + N + S G
Sbjct: 22 NENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFSDDSDKFSLDPASGLISVAAALDFEA---------TPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYV-----GTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARA---LDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEY--GQLSLIYSLEGSTQFRINARSGDITSTTL------LDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFYRI---------NAASGKI----RTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGL-----ITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDS---VVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLF----LEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSG 727 HSP 3 Score: 144.05 bits (362), Expect = 7.619e-35 Identity = 190/686 (27.70%), Postives = 293/686 (42.71%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISEC-TTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENK-----ASIVVIAADGEGRSNETTIE--LEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFIS--DENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKI-LDREVKDRYEFT------VEAKDNGEP--NLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLS---ATTTL 2451
+ I +I+ NDN P F + + EN + +A D D+ +G S S + F L D + + + V LD E F + A DGGG + R+ + + DVNDNTP + Y E + V+++ A D+D P QI + I S F IT S Y + ++ K S+ ++A DG +T+ +E+ D ND+ P+ +S S+ I EN + V + TD DQ + L +Y+ LE Q F++N+ G DRE S+Y + V D G + I T+ I+ D NDN P + +I E+ G +I V A D D + N + Y+I + IN +G+I + LDRE + F V D G P S + +++ DVNDN P + Y+ +++E F ++ A+D D G NG + + + D Q+ G I +DRE V + + D G P ++TTT+ + VLDVNDN P F +P A + +++ + +A S+V + TD D GLN + + +T N DG + LD + K LV+EA D G P+ S TTTL
Sbjct: 15 RVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFG-----QVSYHFSDDSDKFSL-DPASGL---ISVAAALDFEATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPN--NQITYSILPTSAYSSY----FSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQ-----------SPEYGQLSLIYS--LEGSTQ---FRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAI---DPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLF---QVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTF-HP---ARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNG-PAGSRRTGTTTL 658 HSP 4 Score: 124.405 bits (311), Expect = 7.730e-29 Identity = 179/747 (23.96%), Postives = 287/747 (38.42%), Query Frame = 1
Query: 337 GRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSL---PV-AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKS--FEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA--KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESI-LYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCN--DHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNG------TPTMSSSEIITIFISDENDNPPHFETEFKTF-SISEDAKIGHEIGIVIAKDSDSSPNNIIT---YSIIGDYEVKETFGI--NHNGQIHLNKILDREVKDRYE-------FTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYF---GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
G D + G ++V +DRE + + + +A + + I+D NDN P F +IPEN + ++ P+ A D D +GV S+ YF LID N + + LDRE I E + DGG R+ V + DVNDNTP + + E + V+ + A D+D G +R+ I+ + F I ES L + + + + ++V+A D + + EL + N D + + + + E +V R+ ++ + +N Q DRE Y + V+ D G T + + ++DENDN P FE T + E A G + ++ A D D+ N ++ ++ G + I N +G I+D D E F + A D G P + + + +IVLDVNDN+P I S V E + + A+D D G NG FR+ S + + II NIDRE ++V +D GNPP + + V + V DVND RP F P+ +++ + ++ GS V VKAT+ G N Y + K+ F++ + ++ +L + + L A D G P L LY+ D
Sbjct: 1436 GERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDAD---FGVNATLAYSLLGGSSA-YF-LIDRDRG-NVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGND------TFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGV----TIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVP-IFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGD-KLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPV----QTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIG--KNAFTVHATSGLVTSTRLLKSYERFN-LTAVATDHGRPPLWGQAGLYVEVLDVND 2157 HSP 5 Score: 121.324 bits (303), Expect = 6.587e-28 Identity = 142/560 (25.36%), Postives = 229/560 (40.89%), Query Frame = 1
Query: 739 LDRENIKSFEFHLYASDGG--------GNQGKCRIIVEITDVNDNTPQW-VGLPYRKEISECTTEAKVLQ-LNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIV---VIAADGEGRSNETTIELEI--KDCNDHRPV-IKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQ------LNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFR------VRSRSTPIDIQVY----NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPR-TATTTVHIEVLDVNDNRPKF-TYPLLNA-HNYLNITDDMAAGSIVGEVK-ATDEDFGLNGSIIYNLTNQN 2307
LDRE S+ + + DGG N+ + V +TD NDN+P++ G E+ E +L L+A D+D R ++ + I + +++ A F E + + ++A DG TT L + D ND+ P+ + ++ + E LV + TD D G N + T +E+GG K+ + PG DRE + Y++ V+ D G P +S S I+ + + D ND P F +T S+ E +G + V A ++ N TY I G K F ++ +G + ++L + +R+ T A D+G P L + + VLDVND+ P + +V E I ++ A D D GQNG R+ V SR D + + G I +DRE +++ D G P +T + + + D++DN P F P A + +I + G+ VG V A D D G N + Y + N
Sbjct: 1791 LDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDV-AKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQV----------------TFRIESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIG--KNAFTVHATSGLVTSTRLL--KSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSR----DWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGN 2325 HSP 6 Score: 116.701 bits (291), Expect = 2.083e-26 Identity = 175/734 (23.84%), Postives = 280/734 (38.15%), Query Frame = 1
Query: 436 TGAFLNYIIFAD-------HQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR-----IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQ-----LNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGA---LKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKS-KILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-----GDYEVKETFGINH------NGQIHLNKILDREVKDRYEFTVEAKDNGEPNL------NDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRS-TPIDIQ----VYNEGKI----IYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDR-------LVVEARDQGTPSLSATTTLYI 2457
T AF N I A + + + ++D++DN P F + E A + S A D + + S E F + ++ + V LDRE + + L D N R +IV I D NDN+P + + Y EI E + VL + A D D + + + + S Y +I R + + +G + + + ++ DG R+ + + + D ND+ P V S + + EN + V + D D G+ C + + +GG F ++ GL D E Y + V+ D P ++S + + + +E D F ++SE A G + V A + P + +I+ D K+ N G+I LDRE D Y TV ++D G + + V D NDN PE S +VE E + L+A+DRD G NGT R + + T I Q + NE + + + + I + +D G+PPR+ T + + VLDVNDN P F P +++ + A G++V V ATD D G NG + + + ++ D SI SDG N DR L+V A D+G P LS + + +
Sbjct: 1351 TQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAF----YADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDAD--FGVNATLAYSLLGGSSAYFLIDR----DRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGV-----CDAGTVRY---------SIASGGNDT-FGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAG-SATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSP---GGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRI--ESGGGDKLSIGPSDG-----IIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRV 2048 HSP 7 Score: 113.235 bits (282), Expect = 2.486e-25 Identity = 139/573 (24.26%), Postives = 247/573 (43.11%), Query Frame = 1
Query: 802 QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN-IGALKSFKENKASIVVIAADGEGR------SNETTIELEIKDCNDHRP-VIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN--NIITYSIIGDYEVKETF-GINHNGQIHLNKILDREVKDRYEFTVEAKDNGE-PNL--NDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYI-GKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKI-IYFG-NIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGL--NGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARDQGTPSLSATTTLYI 2457
Q +++ ITD NDN P + Y ++E + A V N D + ++ + I + F I L + AL ++V+ A + R ++ T+ + + D ND P ++ + + + E + + T +D+D G+N E S+ D + + SP + + + + + DRE + Y++ ++ D GTP ++S+ + + + D +DN P F S+SE A + + V A D++ N ++ +S + F + G +++N+ LDRE Y T+ +DN + P+ DS + + +LD NDN P S +Y +I E+ + G + ASD D G N T + + S+ + + G + + G +DRE + + + ++ R AT + + VLDVNDN P F AH N A G+ V VKA D D G+ G++ Y++ + + D F I +I+ P+ L+V A DQ P +A+ L +
Sbjct: 1153 QATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNT-----AATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIAT-FMASDQDSGLNGELEYSIIDGD--PRNEFVISPADGDLRVRRY-------VELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLEN---SPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGN--DTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRV 1705 HSP 8 Score: 99.3673 bits (246), Expect = 3.599e-21 Identity = 151/689 (21.92%), Postives = 274/689 (39.77%), Query Frame = 1
Query: 367 KGDIWVTSAIDREEICQPISKCLT---GAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKT-IKIPENVARSSEFSLPVAKDRDSEKYG-VXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK---VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDR---EKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF--ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVK----ETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCK-IRIIVLDVNDN------IPEISTSY-SFKIVESWEREHKHFYIGKLN-ASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTT-------------VHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+G+I +A+DRE + L+ G + + + + + D NDN P F+ T +++ E+ A + ++ A DRD+ G V + I Y +I + + + D + + F + A DGG + V + DVNDN P ++ P +S A V + A D D GQ+ F+I + I ++ I+ + GA + A +++ A G S + + + D ND RP ++ + E+ V + T+ +G N++++ + G K F +++ GL + R+++ + D+G P + + + + D ND+ P F +I+E + I V+A D D N + YS + V E+F IN +G I + LDRE + Y + A D G+P +S + +++++ D++DN +P+ Y SF I E +G ++ A D D+G N + + + + + G ++ ++DRE ++V N N TT V + + D+ND P FT H Y + D GS + +++A D D G N ++Y +
Sbjct: 1782 QGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLS-PGGYAVSVVELGAPGTLVASVWATDADAGPN--GQVTFRIESGGGDKLSIGP----SDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIA-----------------GIGKNAFTVHATSGLVTSTRLLKSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPE---HSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGNKFNLSRWGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTN-----HEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRI 2438 HSP 9 Score: 92.4337 bits (228), Expect = 4.598e-19 Identity = 118/494 (23.89%), Postives = 221/494 (44.74%), Query Frame = 1
Query: 865 GLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSK-ILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICND---NGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKI--LDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIP---EISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY---NEGKIIYFGN-IDREXXXXXXXXXXXXXNGNPP---RTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
GL + TT ++ +++ + TI G +SE + N + ++I IT+ L + ++ + I + A + T++ + I D ND+ P + + + E + + V +T +D D+G N+ ++ VS ++ T ++NG L ++ L F+ A Y + V D + ++S+ +++ ++D ND P F ++ + + G I +A D DS N + YSII D + + F I+ +G + + + LDRE + Y T+ AKD G P LN + + + VLDV+DN P + + S E + ++ ASD + G+N + S + + ++ ++Y +DRE+V + + + V DN + P R + + + +LD NDN P F+ A N + + G + A+D DFG+N ++ Y+L
Sbjct: 1071 GLANCAGATTLTTLSRGFEMSISQIEAAVTISGA-SGVLSEATLNKQASIKITTITQR-LCTKVLVKRAASASTRGICLTATPAQA---TTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAI-----VSGNTAATFGIDNGTGV----LTAVKALDFE-VSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSII-DGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLS-----EAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSL 1543 HSP 10 Score: 90.5077 bits (223), Expect = 1.746e-18 Identity = 125/544 (22.98%), Postives = 228/544 (41.91%), Query Frame = 1
Query: 481 FELQIEIIDINDNFPSF-QPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNN---INP---YLRVI--GDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYI-TESILYLNIGALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKV--HSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTP-TMSSSEIITIFISDENDNPPHF------ETEFKTFSISEDAKIGHEIG-IVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSC---------------KIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS 1977
F L + ++D+NDN P F P + + E A + + A D D+ G + F + G + I P +RV ++DRE ++ + A D G G + V + DVND P ++ + E + + + ++ + + +KI+ +N F + S L + LKS++ + ++ +A D GR + + +E+ D NDHRPV + + + + I E I + + D D+G N S F+ + + E+ F++N+ G+ DRE + YS+ ++ +D G P + S++ + + + D +DN P F +++FSI E + G +G + A D+D N I+ Y I E F ++ G + + LDREV Y V+A N PN + ++R+ + D+ND P + T++ + + + + + +L A DRD+G N +R+ S
Sbjct: 1937 FNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNG--------------QVTFRIESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVA-TVKATENYKGHNTKYTYKIAGIGKNA------FTVHATSGLVTSTRLLKSYE--RFNLTAVATD-HGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYS-----FLHAGGVGSRDWES------FRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNE-GNKFNLSRWGLLVVLSDLDREVSPYYAIIVKASSN--PNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWP-VFTNHEYTAGVAVDAKVGSELL-QLEAVDRDVGNNSIVLYRILS 2440 HSP 11 Score: 50.8322 bits (120), Expect = 1.999e-6 Identity = 58/240 (24.17%), Postives = 110/240 (45.83%), Query Frame = 1
Query: 1795 SCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN-EGKIIYFGNIDREXXXXXXXXXXXXXNG--NPPR--TATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDR-------LVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+ + I + D NDN P + +++++ + + + ASD D G N + + S +T + N G + +D E + +LV + +P R T+T TV + V DVND P F L + +++++ G + A+D+D GLNG + Y++ + + + +DG + +++ ++ DR L + A+D GTP L++T T+ +R D
Sbjct: 1155 TTSVLIRITDENDNAPAFGAA-TYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWF---LRSYEGPIDVSEGQP-GPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVEL-----DRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHD 1384
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 153.68 bits (387), Expect = 8.806e-38 Identity = 185/733 (25.24%), Postives = 303/733 (41.34%), Query Frame = 1
Query: 202 LSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDRE-----EICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKC--RIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVV-IAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNF-VSLDS---------MYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS--RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLN-ITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
S E+Q P G I ++ +S+ S+ L S G + +VD + G++ V A+D E E+ + + F + + +L+++++DINDN P F K+PEN + L A D+DS G+ SI N F + + I R + LDREN+ S+E + A+D G C ++++ +TD NDN+P++ + + VL+++ D D+ I F + + S + + IT S LN +E+++ V + A + T + + + D ND+ P + ++ E + + LV R++ +D D G N + F NF V DS Y P G + ++YS V D G P +SS +TI I N N P F E + ++ + G I + A D D N I YS++G F ++ G +HL L + + TVEA+D G P L+ I V + N P ++ + E + ++ A+D D G NG + + S S DI G ++ G +D E ++ V D G +T + V I V DVNDN P+LNA +Y I ++ +G+ V + A D D N +Y+L + DLF +
Sbjct: 239 FSFREDQPP----GTTITVVA--ARSSRRAGPVSYHLAS--GGNLG-DVFAVDPQSGEVSVHRALDHEYQHHYEL---VVEARDSGFPPFSAY-----LKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVL-TAVDKDS---GINGQVDYSIIDGNIGNVFRVNPNSGEI----RSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSAHVREDAAVGFPVLRVSTLDADEGPN--AAITFSLLDPSLPFSIHPSTGEITVS-RRLN-------REDRSGYAVKVRASDPAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANL----------------NKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGG-NASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRF--AHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDIS-RASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNP-----PMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSL--DDGEADLFVL 909 HSP 2 Score: 149.828 bits (377), Expect = 1.419e-36 Identity = 173/682 (25.37%), Postives = 282/682 (41.35%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVI---GDLDRENIKSFEFHLYASDGGGNQG---KCRIIVEITDVNDNTPQWVGLPYRK-EISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISEN-SQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQG--INSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNH-------TKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKP 2472
+ + + D NDN P F E +PE+ S+ +L A D D+ + Y L+ + +F ++NP I LDRE +S+ + A DGG G ++V +TDVND+TP+++ PY S V + A+D D G +RF +S + S + + R I + AL+ +++ ++ V +DG RS TT+ + +D + P S +E++ +T + + ++ + N + ++D G+ + + D E Y + V D+G P S+ + + + D NDN P F + + E+ I ++ A D DS N + YSII D + F +N N G+I LDRE YE TV+A D G P + + K+ I V D NDN P + +S + E F + +++ D D G N F + S P I + G+I ++RE V V +P T +T V I V DVNDN P+F Y+ + ++V V A+D D G NG + + + +Q + ++ S++ N VV A D+G P LS+ T+ I P
Sbjct: 12 VTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRLRGG-----DGHF-------SVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDAD--AGPNGDLRFSLSGSASAGFSVDPRRGVIHAAR------ALQGPRDD-LTLTVRVSDGGAPPRSAVTTVTVRFRDAGEF-PRFAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLGDVFAVD-------PQSGEVSVHRA-------LDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPP-RTIVVLTAVDKDSGINGQVDYSII-DGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSAHVRED---AAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHP-STGEITVSRRLNREDRSGYAVKVRAS---DPAWTVSTDVTIVVDDVNDNAPRFG----QTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVP 644 HSP 3 Score: 140.198 bits (352), Expect = 1.183e-33 Identity = 128/454 (28.19%), Postives = 212/454 (46.70%), Query Frame = 1
Query: 1141 IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDI-----QVYNEGKIIY---FGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+E+++ D ND+ P K+ EN + +V +T D+D GIN + S+ D N +F++N G DRE + Y + V D G+PT + + I ++DENDN P F T+ + + EDA +G + V D+D PN IT+S++ + F I+ G+I +++ L+RE + Y V A D P S + I+V DVNDN P T+Y + E E E + +++ASD D G NG F +RS++ + ++++ + Y G ++K +V +D G PP ++ TV I ++ N N P+F L + + AG+ + ++ A D D +NG I Y++ N ++ F + + G + L+ L + + VEARD+G P LS+ T I
Sbjct: 322 LEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSIIDGNI----------------GNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF-TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLL---DPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEA---LVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRF----LRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRR-FDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAII 743 HSP 4 Score: 128.642 bits (322), Expect = 4.730e-30 Identity = 136/514 (26.46%), Postives = 222/514 (43.19%), Query Frame = 1
Query: 805 GKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIV--VIAADG---EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY-------NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
G + V + D NDN P++ R + E + V +NA D D + I +++ ++ + I + +L +E + S V V A DG G S+ T+ + + D NDH P + + V +T D D G N + FS S + + S+D + I ++ G D ++ V +D G P S+ +T+ D + P F ++FS ED G I +V A+ S + ++Y + + + F ++ +G++ +++ LD E + YE VEA+D+G P + K+ + VLD+NDN PE S+S + K+ E+ I L A D+D G NG + + ID + N G+I +DRE V ++ V D G+P + T V I V D NDN P+FT + +AH + +D A G V V D D G N +I ++L
Sbjct: 8 GTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDAD--AGLNAIISYRLRGGDGHFSVNPSTGQI------ITTASLD--REGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPR---------RGVIHAARALQGPRDD------LTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFP-RFAPGPRSFSFREDQPPGTTITVVAARSSRRA--GPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPR----TIVVLTAVDKDSGINGQVDYSI------IDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQ-IFSAH----VREDAAVGFPVLRVSTLDADEGPNAAITFSL 478 HSP 5 Score: 117.857 bits (294), Expect = 7.499e-27 Identity = 168/687 (24.45%), Postives = 282/687 (41.05%), Query Frame = 1
Query: 346 LISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAK----DRDSEKYGVXXXXXXXXXXXXXENYFELIDHGN--NINPY---LRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN----IGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKA----SRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
+ V+ G+I S +DRE + S LT + H ++ I + D NDN P F T +V + PV + D D F L+D +I+P + V L+RE+ + + ASD + + + DVNDN P++ Y E E + EA V +++A D DD GQ+ F + ++N+ + R S+ L G NK S VV A D GR S++ T+ + I N + P S + ++ + ++ D D+ +N + + S+ G + F +++ L+ A S +SV V D G P +SS I +++EN P F S+ E+ G + V A D+D+ N I YSI GD F I+ +G + L LD E + Y +V A D G + + I V DVNDN P ++ S + ++ E + ++A D D N + + D+ V N+ G + G +D E ++ V + + +T VH+++ VN+ P+F + +N++ +++ G+ VG V ATD D G++G++ Y L ++ +K FS+
Sbjct: 382 VFRVNPNSGEIRSVSTLDRENV---ASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF-----TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAIT--------------FSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWTV-STDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADD--GANGQVFFFMRSQTENFR-VGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMD-RGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSV----------------VGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDG--SGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIP--ENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEA--DLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRF---VQREYNFV-VSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKG-FSV 1014 HSP 6 Score: 114.39 bits (285), Expect = 9.107e-26 Identity = 99/336 (29.46%), Postives = 153/336 (45.54%), Query Frame = 1
Query: 1459 GTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGE-PNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
G P ++ + +T+ + DENDN P F ++ EDA IG ++ +V A D+D+ N II+Y + G F +N GQI LDRE ++ Y V A D G P L+ S + + V DVND+ P + S + + A D D G NG RF + S S V +I+ + D + + V V D G PPR+A TTV + D + P+F + +D G+ + V A G + Y+L + + D+F++ G++ + + LD + ++ LVVEARD G P SA L +
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRLRGG---DGHFSVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVF--AVTARDADAGPNGDLRFSL-SGSASAGFSVDPRRGVIHAARALQGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEF-PRFA----PGPRSFSFREDQPPGTTITVVAARSSRRA--GPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEV 324 HSP 7 Score: 105.145 bits (261), Expect = 5.738e-23 Identity = 141/565 (24.96%), Postives = 239/565 (42.30%), Query Frame = 1
Query: 808 KCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVL-QLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGL-----YFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNL--NDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNG-TFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLN-GSIIYNLTNQNHT-KDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ I+ +T+ N P++ P + E L ++ A D D + G I + I+ S + + I + +L +G L E ++ V AADG + ++ + + + + D ND+ P++ I EN S V + D D N+ SL+D G+ +F LN G+ + D E Y + V + S+ + + I+ N+ P F F +SE A +G +G V A D D+ + + Y + G+ K F +N H G+I ++ LDRE + V AK+ G D + + + D ND S Y ++ E+ ++ ++A D D TF F ++S + + + G I+ +DRE V ++ V +D G PP T TT V + + DVNDN P LL + +T++ AG V ++A D D N G + L + + FS+ S G + + +D + K L V D G+P L++T TL++
Sbjct: 738 RATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTD--AGVNGAIVYSIA--SGDGSGLFDISRASGDVLL--VGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDD-----------------GEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSK-GFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEA---ASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPF----LLTSS--AKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHL 1269 HSP 8 Score: 93.2041 bits (230), Expect = 2.666e-19 Identity = 113/457 (24.73%), Postives = 200/457 (43.76%), Query Frame = 1
Query: 1114 GEGRSNET-TIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNG-TPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIST---SYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
GE R T T+ + ++D ND+ P + E+ V + TD D G+N+ S L D ++ N +I S+ DRE Y +EV D G TP +SSS + + ++D ND+ P F A G + V A+D+D+ PN + +S+ G F ++ G IH + L + +D TV D G P + + + D + P + S+SF+ E + I + A R + G + + S D+ + G++ +D E +++V+ D+G PP +A + ++VLD+NDN P+F+ ++ + + ++ +IV + A D+D G+NG + Y++ + N ++F + + G+I LD + L V+A D+G+P+ T + I
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRLRGG-----DGHFSV---NPSTGQIITTASL-----DREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSG--SASAGFSVDPRRGVIHAARAL-QGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFR-----EDQPPGTTITVVAA--RSSRRAGPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFS----SSRFWAKVPENTPPRTIV-VLTAVDKDSGINGQVDYSIIDGN-IGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLI 428 HSP 9 Score: 63.1586 bits (152), Expect = 4.274e-10 Identity = 90/375 (24.00%), Postives = 150/375 (40.00%), Query Frame = 1
Query: 433 LTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQG----KCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYI-TESILYLNIGALKSFKENKASIVVIAAD-GEGRSNETT-IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINS---EFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNP 1524
LT NY + ++ ++I +N+ FP F E + E+ + A DRD+ G+ + F + +H I V LDRE S + A + G +G + + V ITD ND P + Y +SE + V+ ++A D D P G F S N R F I + L + L ++ V+A D GE + TT + + ++D ND+ P + +SS K+ EN+ + + V + D D N F +D + S+ +S L + DRE+ + + V D G+P ++S+ + + + D+NDNP
Sbjct: 932 LTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDA---GIDGTVFYMLFGESRSKGFSVNEHTGEII----VSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPP---GWRTFSFLIQSGNAG---RAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLL--TSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARP------------IDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNP 1278
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 191.815 bits (486), Expect = 2.490e-49 Identity = 187/676 (27.66%), Postives = 299/676 (44.23%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTT-EAKVLQLNAQDKDDP-------QTIGGQIR--FKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYF-GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
L I + DINDN P F P ++ EN ++ S A DRDS G + + + ++ ID I + + D EN ++ + A D G ++ + I DVND++P + Y K+I E T + V+ + A D D + I G ++ F I NS + + + T L + A +++S T + + ++D ND+ P+ + ++ E+ + ++ TD D N + +L+D +F +N+ GL D EK ++Y V V D GTP+ SS ++ + + D NDNPP F T ++ E+ G + V A D+DS N I+YSI+ E F ++ G+I LDRE Y T+ A D + + I + D NDN P + F I E + +G+L A+DRDIG NG + + S + Q+ I+ +DRE + ++V D G+P ++ T ++H+ VLDVNDN P+F L + I +D + S V +VK D+D G NG+I +L+ + D F+I S G ++ K LD + +L V ARD G+PS SAT + I
Sbjct: 362 LLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVS---ATDRDSSTNGALVFGIIKGN----DDGVFTIDGSTGI---ISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSS-------------STRVTIALQDINDNSPIFQ-GPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD------------------NTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNE-NMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTR---VGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGE----IREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEG--SDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKI 985 HSP 2 Score: 188.734 bits (478), Expect = 2.048e-48 Identity = 177/623 (28.41%), Postives = 271/623 (43.50%), Query Frame = 1
Query: 472 HQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL---NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNH 2310
H F I + D+NDN P F + E+VA S A D D G+ S+ S +YF + G +R G DRE S++ L A DGG G+ + +EI DVNDN P + Y + E A ++ + A DKD+ +R+ + + N+ F + + + F++ + + ++ G ++ + + + + D ND+ PV + ++KEN + T+++ TD D N + ND ++D G I + P D E +RY + V D G P + +TIFI D ND+ P F + I E IG + V A D DS P + Y +I VK F I+ N G I ++ LDRE Y VEA+D G + + S ++ I + D+NDN P Y F++ ES H+ IG++ A+D D NG R+ + + I + G I +D EK + V V D G P R++ T V + V DVNDN P+F L + +++AAG V V ATD D G NG I Y++ + N
Sbjct: 149 HTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLD---VGINARLSYSLVSGDT-SYFTVDSQG-----VIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGN--NADLRYSFTSGNTNHA-----FTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNGALVFGIIKGNDDGVFTID----------GSTGIISIAKSP----DYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISG-NVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQ---IGQVAATDADDSSNGDVRYALSDNTDVFSINT-STGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTC----TVGENLAAGVAVCYVTATDADSGANGKISYSILSGNE 729 HSP 3 Score: 188.734 bits (478), Expect = 2.157e-48 Identity = 189/704 (26.85%), Postives = 312/704 (44.32%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASD--GGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGA-LKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNK 2556
++ I I D+ND+ P F P + +IPE+ S A D DS G + S + F + + +I RV +LDRE S+ + A D R+ + + D+NDN+P + G PY +SE ++ ++ Q+ A D DD G +R+ +S+N+ +F I S + + L K+ + + V A DG RS+ T +++ + D ND+ P + + EN + + V +T TD D G N + S S + +G + F ++ G + DRE + YS+ + +D ++ + I I+DENDN P F T F+ISED+ G +G + A D D PN +TY+II + +F ++ +G + + LDRE Y V+A D G P + + I + VLDVNDN P S +S +I E H + ++ D+D G NG + + + + + G ++ +D E + V D G+P ++AT V I +++VNDN P F P +I +D+A + V ++ ATD D + +++ N QS G I + K+LD + LVV A + G+ S IR D N+ NP Y +++++
Sbjct: 463 QVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRG---RLEYRLISGNVKGAFNIDANSGSI----RVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQG-PYVFRVSESSSPGHQIGQVAATDADDSS--NGDVRYALSDNTD-------VFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYS----------------ILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQ-GNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEI---REDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSD-NFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSP----AQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVND----------NAPVFNPGSYAKSLHE 1110 HSP 4 Score: 186.808 bits (473), Expect = 8.981e-48 Identity = 189/681 (27.75%), Postives = 308/681 (45.23%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN-EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDR 2490
++IEI+D+NDN P F + T + E+VA + A D+D+ G S +S + F L + + + V LD E S+ L +D G +++ + D+NDN P + Y+ + E T Q++A D+D + G + F I + + + +F I S ++I ++ + + A G + + + + I+D NDH PV + S +I E+ V +T TD D G L +G K F +++ G DRE YS++V D G+ + SSS +TI + D NDN P F+ + F +SE + GH+IG V A D+D S N + Y++ + +V F IN G I L LD E K +Y TV AKD G P+ + ++++V DVNDN P+ + S Y+ + E+ Y+ A+D D G NG + + S + + + G+I +DRE + + ++ D A TTV+I + D NDN+P FT P + NI++D G+ VG++ ATD D G NG++ Y + + N G + ++ LD + LVV+A D G+P S T ++++ D+ R
Sbjct: 257 VEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDN---GNNADLRYSFTSGNTNHAFTL----DAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT--QVSATDRD--SSTNGALVFGIIKGNDD-----GVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYR----------------LISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPY-VFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDV---FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYV---TATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-----SRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPR 893 HSP 5 Score: 172.94 bits (437), Expect = 1.841e-43 Identity = 191/673 (28.38%), Postives = 305/673 (45.32%), Query Frame = 1
Query: 493 IEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKAS--IVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-----GDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
I++ D NDN P F + I EN +++ ++ A DRDS + S EN F + N+ +R + LD E S+ + A D G ++ + DVNDN P + Y+ + E + V QL A D D I ++ + + +Y F + + GA +E KAS + + A DG RS + T+E+EI D ND+RPV + + E+ + +T +D+D G N++ S +G F L+++ G+ D E+ S Y++ + D G+P ++ + + I ++D NDNPP F + E+ G ++ A D DSS N + + II G + + + GI I + K D E K RY+ TV+A+D G P D+ ++ I + DVND+ P S S YS +I ES + + A+D D G G +R+ S + + N G I +DRE + V+ D G+ R+++T V I + D+NDN P F P + +++ + G +G+V ATD D NG + Y L++ D+FSI S G I LK +LD + K + V A+D GTPS S+ T + +
Sbjct: 58 IDVKDENDNAPEFPLNSYVFNIRENTP-AAQVAIVTATDRDS-----GTNAAITYSLFSGENKFMM----NSKTGEIRTVTPLDHETKDSYTMRISAFD--GKHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLD--VGINARLSYSLVSGDTSY------FTVDSQGVIRTKGAFD--RETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFT----------------SGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVS---ATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGI-----ISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGST---VVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYV-----FRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNT---DVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKV 673 HSP 6 Score: 164.851 bits (416), Expect = 5.104e-41 Identity = 202/731 (27.63%), Postives = 319/731 (43.64%), Query Frame = 1
Query: 355 VDQKKGDIWVTSAIDREEICQ---PISKCLTGAFLNYIIFADHQIFE-LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGD---LDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI---GALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRD---------IGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+DQ G I V +DRE + TG+ ++ I ++D+NDN P F P + EN+ + A DRD + + S + FE +NP ++ LDRE+ S+ + A D G I + I D+NDN+PQ+ Y ++E T +L++ A D D G R S S N+ RI T I + + AL S+ + I+A G + + + + D ND+ P+ + +S I E V +T TD D+G N++ +S DT+ ++++M NG ++N RE Y++ + +D G+P M+S + +T+ ++D NDNPP F ++ S+ E++ + V A DSD N ++ YSII + K F IN +G I LD E K +Y V A D+ + I V+++ND P + +Y+ + E + K++ASDRD +G + +F + RS G I +DRE V + V V D GNPP + T V I++LD NDN PKF ++ +I ++ A S ++ ATD D G N I YNL+ D F I S G I L + LD + K+ L ++ARD GTP +++ T+ +
Sbjct: 1044 IDQSSGLISVAKRLDRETTANYTLVVRATETGS-------QGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGE----NAKVTYELSVGDTSKFE-------VNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPD----AGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYN------LTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAM------NGVLTVKKEIN--------RETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKR-FKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASV---RENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRS----------GIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFD----SSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRN----DAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRV 1707 HSP 7 Score: 162.155 bits (409), Expect = 3.607e-40 Identity = 190/684 (27.78%), Postives = 306/684 (44.74%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGD------LDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIG--GQIRFKISENSQ--NYEMIVR--IFYITESILYLNIGALKSFKENKASIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLN---DTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIG----KLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+++ + D+NDN P F T + EN+A A D DS G +Y L + N R G+ LDRE I S+ + A DG + + + I D NDN P + G P R ISE T +V QL A D+D IG G + + I +Q ++++ R I + + L+ + S+ ++VV A+D +S +I + + D ND+ P + S +I+E+ V ++ V D+D+G N + SL+ NF ++DS F L+ P D E + Y + V D G+P+ S++ + I I + NDN P F + + SI ED I + + A DSD +P +T+ I+ + +F I+ +G I + K LDRE Y V A + G + I VLDVNDN P + SY+ + H++ IG K+ A+DRD G+N + + T G + +DRE + V +D+G P ++A + + + D+NDN P+F+ + L +T++ A GS + V A+D D G NG + Y++ + NH + F I S G+I + +D + L + A+D G P +T + I
Sbjct: 671 VKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANG-------------KISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTG-PSRFNISEDSPTGTRVGQLTATDRD----IGPNGAVTYAIISGNQGNSFQLDPRSGILSVRST---LDRETIPSY-----TLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNF-TIDSTG------------FVLSKTP---LDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP---LTFDIV-EGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSL-------HENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFS----QSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNH-GNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAI 1296 HSP 8 Score: 150.599 bits (379), Expect = 1.240e-36 Identity = 170/653 (26.03%), Postives = 281/653 (43.03%), Query Frame = 1
Query: 355 VDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHG-------NNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKC--RIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGL-----YFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE-GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDED 2262
+D G I V +DRE + S LT + + + + I + D NDN P F +E + I E V+ S ++ A DRD F I G N +N L V +++RE + ++ + ASD G + V + DVNDN P + Y + E + ++ VL + A D D +G + S S N E + F I + + F+E + + A + +T + + + + ND P + + ++EN + V +++ +D D +F SL + + G F ++ G+ DRE S Y+++V D G P +S+ +TI I DENDN P F++ + SI E++ + A D+D N ITY++ + F I +G I L + LDRE K Y+ ++A+D+G P S IR+ V+D+ND+ P I++S V E + K ++ ++ ASD D G N F + S + N G I +DRE+ + + V D GNP ++ V I+V+D +DN P+F N + I++ + G+ + +V A D D
Sbjct: 1253 IDSTTGRITVVGVVDREALA---SYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRD---------------EGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSD----VGANAVLRYSIISGNDE---KRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRD--------------SFGSL----SYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNL----SRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVR--ENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYN----VTISESLPRGASIVQVTARDID 1852 HSP 9 Score: 150.599 bits (379), Expect = 1.251e-36 Identity = 176/689 (25.54%), Postives = 297/689 (43.11%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKC---RIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYIT---------ESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGL-----YFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDED-FGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+++I II++NDN PSF + IPE+VA ++ A D D I + F+ ID + + + V LDRE ++ + A++ G+QG+ + + DVNDN P + Y K + E V ++ A D+D+ + + + S+ +E+ +T ++ L + A+ K +++++ I L I D ND+ P +L + EN + + R+ +D D G N + S + +G F+++S G DRE + Y++ + D+G P S+ + I ++DENDN P F + ++ I E IG + +V A D D N + YSI+ GD F IN NG + + K ++RE Y T+ A D G P + ++ ++V DVNDN P + S S+ I E + + + A D D+G N R+ + S + ++ G I+ +D E+ + + V + TA T V I V+++ND P FT NY ++ ++ + V +V A+D D F GS+ Y++ + D FSI Q G I LD ++ + + V D G P LS T + I+ D
Sbjct: 982 QVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTPL------TFDIVEGNAGSSFK-IDQSSGL---ISVAKRLDRETTANYTLVVRATE-TGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK-FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAIT-------------LTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYS----------------IISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGD---TSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDN-PPVFNSQSY-IGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTAT---DSKYTAKTNVTIRVINLNDITPAFTQ-----QNYTASVRENSPTSTSVVKVSASDRDSF---GSLSYSIVGGKDS-DKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDEND 1612 HSP 10 Score: 148.288 bits (373), Expect = 5.647e-36 Identity = 197/761 (25.89%), Postives = 332/761 (43.63%), Query Frame = 1
Query: 355 VDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKE-NKASI----VVIAADGEGRSNETT---IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYL-NITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNA 2580
V+ G + +DRE+ S L +++ + + + + I D+NDN P F + T+ + EN A S +A D D+ G SI S + N F + ++ + V+G +DRE + S+ + A D G V IT D NDN+P + I E + ++V + A D+D+ N+Q + IVR +I +N G L KE N+ ++ + I A G T+ + + + D ND+ PV S ++EN V + D D G N+ S+ +G +K F++NS G+ D E+ S+Y +EV D+ ++ +TI + + ND P F + T S+ E++ + V A D DS + ++YSI+G + + F I+ +G I +LDRE+ Y V D G P L++ + I +LD NDN P+ +S + E + KL A+D D G N + + SR+ I + G I +DRE D+ + D+G PP+ ++ T+ + V+D+ND+RP L+N+ + ++ ++ + V + A+D D GLN + ++L + H K +F++ + G I K LD + + L + D+G PSLS+ + I D N P +Y T+++S LP A
Sbjct: 1148 VNPATGLVTTKRPLDREDQA---SYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDA---GANGRVTYSIISGNHGNAFRI----DSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDE------------GSNAQVFYSIVRGDTSAFAINAMN-GVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI----------------ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGS--LSYSIVGGKD-SDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSI--LENSAPSSFSFKLAATDADEGTNARITYNL-SRNDAFMIGA-SSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRP-----LINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEH-KSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDD----------NCPRFQPTEYNVTISES--LPRGA 1841 HSP 11 Score: 134.806 bits (338), Expect = 9.664e-32 Identity = 152/578 (26.30%), Postives = 243/578 (42.04%), Query Frame = 1
Query: 739 LDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIG-------GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL--NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY----NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYL-NITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARD 2415
DRE+ + + A D ++G+ +++++ D NDN P++ Y I E T A+V + A D+D G+ +F ++ + + + + T+ + I A +G+ + + D ND+ P + + E+ +V ++T D D GIN+ S SL DT++ ++DS + G FDRE + Y V + D G+P+ S + I I D NDN P F + T S+ ED IG + V A D D+ N + YS F ++ G + +++ LD E + Y + D G P L D+ + I V D+NDN P S ++Y ++ E+ +++A+DRD NG F + + D V+ + G I + D E + D+ V D G P + T V I + DVND+ P F+ NY I + GS V V ATD D G G + Y L + N K F+I ++ I + P L VEARD
Sbjct: 28 FDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRDSGTNAAITYSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAF-----------------DGKHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGV--IRTKGA-------------FDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSG-NTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT------QVSATDRDSSTNGALVFGIIKGN---DDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFS-----PSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGN-VKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARD 557 HSP 12 Score: 130.568 bits (327), Expect = 1.874e-30 Identity = 125/423 (29.55%), Postives = 190/423 (44.92%), Query Frame = 1
Query: 1348 LENGGQKKIFQLNS------IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLT--NQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR---------YFKPRDSFDRSNENSMNSKYINPKDYPRTVNKS 2559
+ +G + +F ++S G FDRE SRY + V+ D ++ I + DENDN P F F+I E+ ++ IV A D DS N ITYS+ + + F +N G+I LD E KD Y + A D I V DVNDN P + S Y + +E + +L A D D+G N + + S T V ++G I G DRE V + D G+P R+ TV IE+LDVNDNRP F+ +A ++ +D+A G+ + V A+D+D G N + Y+ T N NH L ++ G + + + LD + ++ L + D+G+P L+ T+ L I F P R EN+ ++ D + N +
Sbjct: 3 IMDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTP-AAQVAIVTATDRDSGTNAAITYSL---FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKHTTF----VPLITVDDVNDNAPFFALSVYKTGV---YEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY-FTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFS----SAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVT--GVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVSATDRDSSTNGA 407
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 184.882 bits (468), Expect = 3.631e-47 Identity = 206/689 (29.90%), Postives = 300/689 (43.54%), Query Frame = 1
Query: 481 FELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPV-AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNN-------INPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRI---FYITESILYLNIGALKSFKENKASIVVIAADGEGRS---NETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPD-RLVVEARDQGTPSLSATTTLYIRYFKPRDS 2481
+L I ++D+NDN P F+ + IPE+ + +F L V A D DS G Y L G+N ++ + V+ LDRE + ++ + A D G + V+IT DVND TPQ+ Y I E V + A D D Q G++ F+I S N N+ I RI + + + Y IG +++ A +G+ N+TT+++ + D ND+ P I EN R+ D+D G N E FS ND F S EN G I + DREK +++ + D G P + ITI + D NDNPP F E SI+E+++ G + V A D DS P N++ YSI+ F IN G I L+ L+ K Y F+V A D L+ + + + V D N + PE SYS ++ E + + A+DRD G N + + + + G I G++DREKVD V D+G P A + V+I + DVNDN P F P A + +D+ G V EV A+D D G N IIY+ + + F+I S II K + P+ L V A DQGTP A+ + + +DS
Sbjct: 112 MDLTINVLDVNDNGPIFERNIYAADIPEDKS-IGDFVLAVRASDADSGSNG-------------EVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCD--QGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFN---------LLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLPF--------SINENTGGISIKE-------ELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVV-YSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTS---VLTVLATDRDTGSNAKISYSIATLVPEFSVD-ETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEA----KVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDS 748 HSP 2 Score: 141.739 bits (356), Expect = 7.057e-34 Identity = 153/567 (26.98%), Postives = 237/567 (41.80%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY----NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRP 2160
+ I +ID+NDN P F IPEN A EF A D+D G + S + F + ++ I+ + +LDRE + F F + A D G +G +I + + D+NDN P++ Y I+E + VLQ+ A D D T + + I +S + R F I L + + ++ + ++A S+ + + + D N H P K S S ++KE+ V + TD D G N++ S S+ +L ++ G K L DREK Y EV D+G P + + + I I+D NDN P F + ED + G + V A D+D N I YS + + + TF I+ G I K LDRE YE TV A D G P S K+++I+ DV D+ P Y + E + + A +D+ + + ++P QV+ N G I +D E + + V + P TTV + + D+NDN P
Sbjct: 325 VDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNG-----EITFSFMQNDLPFSINENTGGIS----IKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT---NVVYSIVSSSGHD----RCFRINPQGL-ITLSCTLNYNTKHVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI-----ATLVPEFSVDETTGVIKTAGSL--------DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSP---VITVKAKSQDLSPETGMMYSIVRGNSP---QVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLS---PFFTETTVMVYLKDINDNTP 852 HSP 3 Score: 134.806 bits (338), Expect = 1.046e-31 Identity = 114/321 (35.51%), Postives = 170/321 (52.96%), Query Frame = 1
Query: 1516 DNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKET--FGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+NPP F + S+SEDA++G + V A D DS N +I YS+ + F I+ G I + LDRE DR+ F V+A+D GEP+L + I VLDVNDN P + Y+ I E ++ F + + ASD D G NG ++ + + E G + +DREKV + V D GNPPR+AT TV I +LDVND P+F+ + +A I +D+ +V V+ATD D G NG + + + + N + FSI + +G++ +K+KLD ++ L+V A+D+G P L TT+ I
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPE--DKSIGDFVLA-VRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSA----TIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDM-NFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDI 327 HSP 4 Score: 132.88 bits (333), Expect = 3.401e-31 Identity = 170/636 (26.73%), Postives = 264/636 (41.51%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHG-------NNINPYLRVIGDLDRENIKSFEFHLYASDGGG----NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGA-LKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPE-ISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSR-----STPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQN 2307
++I ++D+ND P F + I E+V + + A D D G E +FE++ N IN +RV LD E I F + A D G NQ + + + DVNDN PQ+V ++ I E + ++ A DKD G+I F +N F I E+ ++I L K K + + A D E T ++ I D ND+ P I EN + V ++ D D G TN V S + + G + F++N GL + Y V +D +SS+ ++ + ++D N + P F+ + + EDA +G + V+A D D+ N I+YSI + ++ V ET G+ I LDRE D Y F V A D+G P L + I + DVNDN P + SY K+ E + + +++ASD DIG+N + S + ID +G I +DRE + + ++ V D G PP A+ V + + DV D+ P F PL + + +D S V VKA +D ++Y++ N
Sbjct: 220 VKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNG--------------EVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTT--VDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD--HGTNGEITFSFMQNDLP-------FSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG----------PTNVVY------SIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGV-----IKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGR---VIEVSASDADIGKNAQIIYSFASNGDGQGTFTID---STQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYE----VTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGN 795 HSP 5 Score: 98.5969 bits (244), Expect = 1.247e-20 Identity = 128/505 (25.35%), Postives = 206/505 (40.79%), Query Frame = 1
Query: 484 ELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP--YLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYL-NIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFR 1962
++ I ++DINDN P F +E I EN + A D DS V + S D INP + + L+ + F + ASDG + + V +TD N + P++ Y E+ E + VL + A D+D +I + I+ +V F + E+ + G+L K + V A D ++ + + I D ND+ PV S K++E+ + V ++ +D D G N++ S F S NG + F ++S G+ DRE Y + V+ D GTP +S + + + D D+PP FE ++ ED + V AK D SP + YSI+ + F IN N G I LD E + Y TV A + P ++ + + + D+NDN P + + V+ + + Y K+ A D D+ TF+
Sbjct: 427 QITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGH----------DRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDGMLSS-TALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSN--AKISYSIAT-------LVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYS-----FAS----------NGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRG-NSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLS--PFFTET-TVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARY--KIPAYDPDVSDKLTFK 890
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO35413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLL0]) HSP 1 Score: 167.933 bits (424), Expect = 5.255e-42 Identity = 181/674 (26.85%), Postives = 273/674 (40.50%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV----RIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELE--IKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPR-TATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDE-DFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
+ I + D+NDN P F DE T+ I ENV + A D D+ G + + N F + I G DRE + ++ ASD G C ++V + D NDN+P++ L Y +I+E A + ++A D D I EN++ IV F + + +G + SI V A D ++E+ + D NDHRPV H ++ I EN + + D D G+N+E + FV+ G F +NSI G DRE R+++EV+ D G P S +T+ + D NDN P F +SE + I V+A+D D + +TY I E F IN N G I + LDRE K +Y V+A D G P L+ + + VLD ND+ P + + V+ E + K++A D D+G N + + + I F I L N PP A + IEVLD ND+ P F + + L D +G +G V+A D+ D+G N + Y + N T G++++ L + + V A D G P +S T +Y+
Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDA---GDNAKVSYATYGGSHGNKFAIDASSGRI----YTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDAD------------IGENARLTYSIVSPEKATFSMNPVTGEITVGQRLDREGANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYA-----FVT-----------GNSNNSFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSE-GVVESNIVTVVAEDRDIGSDGSVTYCITQGRE-GGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPAT--LTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYST---------GMITLNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVF----IKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYV 622 HSP 2 Score: 150.599 bits (379), Expect = 1.152e-36 Identity = 141/454 (31.06%), Postives = 219/454 (48.24%), Query Frame = 1
Query: 1141 IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-LY----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN-EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
+ + ++D ND+ PV ++ I EN V +T TD D G N++ S Y + + G K F +++ G +Y FDRE YS+ V +D+G P+ SS+ ++ + ++D NDN P F F I+EDA +G IG V A D+D N +TYSI+ K TF +N G+I + + LDRE + Y V A D G P L+ S +I +IV D ND+ P + ++ E I L A D D G N R+ + ++ + + G++ N+DRE + + V D G P + + T V + + DVNDN+P FT A +++ + +IV V A D D G +GS+ Y +T Q LF I ++ G I + KLD + K+ L V+A D G+P+LS+ + + D
Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVS--------------YATYGGSHGNK--FAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPE--KATFSMNPVTGEITVGQRLDREGAN-YSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFID--ENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAE----VSEGVVESNIV-TVVAEDRDIGSDGSVTYCIT-QGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQND 427 HSP 3 Score: 117.857 bits (294), Expect = 1.185e-26 Identity = 153/614 (24.92%), Postives = 255/614 (41.53%), Query Frame = 1
Query: 493 IEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEIT--DVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIV--RIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETT------IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVIC----NDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNI---ITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQN-GTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDF 2265
+E+ + N + P F E++A S A DRD +G I + + YF + N L V LD E+ +++ ++ A+DGG V IT DVNDN P + + YR E++E TT V+ + + D + +R+ I S + ++ R I ++ + F+ +S ++IAA EG S + T + + I N+ PV + + EN V R++ TD+D+G D + L ++ F L+S G D E+A ++ VI ++ TP+ + I + ++D ND PP F + ++E ++IGH + V A D DS +I I+ G+ V + G + LDRE Y TV A DNG P + + + + + D+NDN P ++ V E + + + LNA D D+ N G F++ + + G + ++DREK D ++ + V D +H+E D NDNRPK T + H + + G +V +V+ D D
Sbjct: 622 VEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRD---FGRNGEISYDIIAGNSQEYFGI----GLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATVEF-------DFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKG----------------PDGVVLYHLLGSDNQQGFDLDSNTGTLSVSGDLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFLKSVYSAHVTEGSRIGHVVTNVTAVDDDSDIRSIRYGISAGNTGNAFVMDAV----TGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVT--ENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDYGSFRLNVSSGVVSTVKSLDREKQDAYNISIKVTDARGLSAVNFCMIHVE--DQNDNRPKATSRDVYVHTF----EGKFLGGVVADVRPDDPDI 1192 HSP 4 Score: 114.775 bits (286), Expect = 1.200e-25 Identity = 156/625 (24.96%), Postives = 269/625 (43.04%), Query Frame = 1
Query: 478 IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITES--ILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDE-DQGINSEF---SCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASR-YSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--GKIIYFGNIDREXXXXXXXXXXXXXNG-NPPRTA--TTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL 2295
+ + + + D+NDN P F E ++ E V S+ ++ VA+DRD G I+ F + ++ I + LDRE + + A+DGG + +IV + D ND+ P + ++ E T + V++++A D D +G + + + N + + F + I L + A + + + + I++E+ D NDH PV L ++ S + + R+ D+ D G N+ + S N T +P E G ++ +S+ R+ ++ Y + V +D G P MS + + + +++ N +PP F S +ED +G + V A D D N I+Y II +E FGI NG ++++K LD E ++ Y V A D G+ +RI + DVNDN P S Y ++ E+ + + + A+DRD + R+ + S D V +E G+I D E +++ D G +P RTA +VHI + VN+ P F + A + ++ G V V ATD+D G +G ++Y+L
Sbjct: 311 VTNVTVVLRDVNDNQPVFTMSEYAAEVSEGVVESNIVTV-VAEDRD---IGSDGSVTYCITQGREGGLFVINENTGTIG----ITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGD----VGSNADVTYSTGMITLNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKA-------------DAAIQIEVLDTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTG-----RFRVAP-ETG---EVLIASSL------RDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNS-QEYFGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAEN--TTPRSVVVCSVRATDRDERGQQSVRYSILGGSGK-DKFVIDERTGEIRATVEFDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTA----TVAENAPIGHSVLRVSATDKDKGPDGVVLYHL 887 HSP 5 Score: 114.775 bits (286), Expect = 1.263e-25 Identity = 168/681 (24.67%), Postives = 274/681 (40.23%), Query Frame = 1
Query: 352 SVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTPQW---VGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFK-ISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD-GEGRSNETT-IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDR-DIGQNGTFRFRVRSRSTPIDIQVYNE-GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
++D G I+ T DRE + + +DH + + + D NDN P F I E+ A + A D D + L S + F + N + + V LDRE ++ + A+D G I V + D ND+ P + +G + E + TE ++ L A D D + +IR+ ++ NS N I I + L+ F ++ V+A D G R + T + + ++D ND++PV + + ++ E +VT V ED+ I S D T + G + +F +N G DRE S+Y++ V D G+P +SS + + + D+ND+ P F T + ED G + V A D D N +TYS T I N I + Y TV A++ P+ I+I VLD ND+ P S ++ + + IG++ A D+ D G N R+ S + +V E G+++ ++ + + V D G P + T V++EV + N + P F+ + +D+A GS + V ATD DFG NG I Y++ N +++ F I
Sbjct: 64 AIDASSGRIYTTGTFDRET---------KDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGE----NARLTYSIVSPEKATFSM----NPVTGEITVGQRLDREG-ANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTE--IITLQAVDGD--SGVNAEIRYAFVTGNSNNSFTINSITGRLRTARNLDRETTPRF-----TLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGVVESNIVT---VVAEDRDIGS--------------DGSVTYCITQGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYS---------TGMITLNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFIK--SVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSE----NEDIAVGSALLTVTATDRDFGRNGEISYDIIAGN-SQEYFGI 684 HSP 6 Score: 87.8113 bits (216), Expect = 2.235e-17 Identity = 125/514 (24.32%), Postives = 215/514 (41.83%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPV-AKDRD-----SEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGK-----CRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKI--SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD------GEGRSNETTIELEIKDCNDHRPVIK-VHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPN-NIITYSIIG-DYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDI 1941
++I + D+NDN P F P E ++ EN S V A DRD S +Y + ++ F + + I R + D E S + A D G + + + + IT VN+ P +V + ++E VL+++A DKD + G + + + S+N Q +++ ++ S G L + + ++ VIA + TI + + D ND +K V+S+ + E + +VT +T D+D I S + G F ++++ G DRE + Y + V DNGTP M+ + + + + D NDNPPH ++E+ G ++ + A+D D +PN YSI G DY +F +N +G + K LDRE +D Y +++ D + + C I V D NDN P+ ++ + V ++E + + + D DI
Sbjct: 725 VRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSG--------KDKFVIDERTGEI----RATVEFDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKD--KGPDGVVLYHLLGSDNQQGFDLDSNTGTLSVS------GDLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDANDPPRFLKSVYSA--HVTEGSRIGHVVTNVTAVDDDSDIRS-----------------IRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDY---GSFRLNVSSGVVSTVKSLDREKQDAYNISIKVTDARGLSAVNFCMIH--VEDQNDNRPKATSRDVY--VHTFEGKFLGGVVADVRPDDPDI 1192 HSP 7 Score: 86.2705 bits (212), Expect = 5.573e-17 Identity = 148/632 (23.42%), Postives = 267/632 (42.25%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENI-KSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYR-KEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKI-SENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSK-ILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNG-TP--TMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKD----NGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTP-IDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFT-YPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLN-GSIIYNLTNQNH 2310
+QIE++D ND+ P F + ++ S S+ + D YG S F + + +I R+++ K++ + ASD G + + VE+T+ N + P + Y+ E + + +L + A D+D + G+I + I + NSQ Y I +T LY++ +EN S+ V A DG E +++ T+ + ++D ND+ PV ++ EN + ++V + TD D+ S+ S L G+ K F ++ G + FD E + + D G +P T + I I+ N+ P F T +++E+A IGH + V A D D P+ ++ Y ++G + ++ F ++ N G + ++ LD E V AK+ + P+ I + V D ND + + YS + E H + ++ D DI + R+ + + +T + G + +DRE + + + V DNG PP T T+ + + D+NDN P T P + +T++ G+ V + A D D N G Y+++ ++
Sbjct: 514 IQIEVLDTNDHAPVFIKSVYLLFAVQDAG--SGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGEV-----LIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRN--GEISYDIIAGNSQEYFGI----GLTNGSLYVSKPLDYEHQENY-SLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDE---------------RGQQSVRYSILGGSGKDK-FVIDERTGEIRATVEFDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKGPDGVVLYHLLGS-DNQQGFDLDSNTGTLSVSGDLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDANDPPRFLKSVYSAHVTEGSRIGHVVTNVTAVD-DDSDIR---SIRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIG-----RVTENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDY 1105
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO36707 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHT2]) HSP 1 Score: 159.844 bits (403), Expect = 9.700e-42 Identity = 150/469 (31.98%), Postives = 235/469 (50.11%), Query Frame = 1
Query: 1090 SIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEI--ITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS--RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTAT--TTVHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL--TNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPD-RLVVEARDQGTPSLSATTTLYI 2457
S+ V+A+DG+ ++ I++ I+D ND PV + S+ I E ++ V ++T D D G NS+ + S+ D N S P N GQ + + D E + + V DNG P + S + +TI I+DENDN P F+ FSI+ED G G V A D+DS N ++YSI D +V++TF ++ G + + +DRE Y F V D+G + + V DVNDN P +Y+ +I E K ++ +A D DIG N + + S + + DI+ +G I+ G +DRE +D+ + + DNG PP+ + V I + D+NDN P+F NA Y +NI++D + G+ V V A+D+D G N + Y + + + K +F + ++ G I LD + N + VEARD G P+L + TT+ I
Sbjct: 25 SVTVMASDGKFQA-FLEIDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVDGN----SSFSIDP--NTGQIIVHRT-------LDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSI-PDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWV---HAHDEDIGPNALITYHIDSGNKESIFDIE---DGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEF-----NASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEI 467 HSP 2 Score: 134.806 bits (338), Expect = 2.164e-33 Identity = 141/491 (28.72%), Postives = 216/491 (43.99%), Query Frame = 1
Query: 721 LRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETT-----IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNL--NDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN----EGKIIYFGNIDREXXXXX-XXXXXXXXNGNPPRTATTTVHIEV 2136
++V LDRE+ S+ + ASDG Q I V I D+ND P + Y ISE VLQ+ A D D Q+ + I + + + F I + + + F+ ++ I+ + A G+ + + + I D ND+ PV S + I E+ + + D D G N++ S S+ D + +K F ++ I G DRE+ YS V+ D+G+ ++++ + D NDN P F + T ISE +G +I V A D D PN +ITY I D KE+ +G I LN LDREV D+Y + A DNGEP D + I + D+NDN PE + S YS I E + + + ASD+D+G N ++ + + + +V++ G I N+D E + V+ DNG P + TTV I V
Sbjct: 10 IKVTRSLDRESNASYSVTVMASDGKF-QAFLEIDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGS--NSQVTYSIVDGNSS-------FSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSIPDEDV----------------RKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHI--DSGNKESIFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQ---VLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEIMV 469 HSP 3 Score: 130.183 bits (326), Expect = 8.761e-32 Identity = 138/518 (26.64%), Postives = 224/518 (43.24%), Query Frame = 1
Query: 352 SVDQKKGDIWVTSAIDREEICQPISKCLT--GAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPV----AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGN---NINP---YLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR----IIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQ-LNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLN-IGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSE--IITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDY--EVKETFGINH-NGQIHLNKILDRE-VKDRYEFTVEAKDNGEPNLNDSCKIRIIV 1818
+V++ GDI VT ++DRE + G F ++ E+ + I DIND +P F P ++ I E S LPV A D DS + + ++D GN +I+P + V LD E +SF + A D G R + + ITD NDN P + Y I+E + V + A D D + ++ + I + E + + F + E L+ +G + + S VV+ D R + +++KD ND++P+ + + +++I E + + DED G N ++ T +++G ++ IF + + DRE +Y++ ++ DNG P S + I+ I I D NDN P F + +ISED IG ++ V A D D N + Y II ++K F +N G I LD E +R++F VEA+DNG+P L + I+V
Sbjct: 2 AVNKTTGDIKVTRSLDRESNASYSVTVMASDGKFQAFL--------EIDVHIQDINDQYPVFSPQNYSVAISE----ESWVRLPVLQVTAVDMDSGS--------------NSQVTYSIVD-GNSSFSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGK--NAKLSYSIPD-----EDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPN----------------ALITYHIDSGNKESIFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEIMV 469 HSP 4 Score: 113.62 bits (283), Expect = 2.237e-26 Identity = 113/347 (32.56%), Postives = 171/347 (49.28%), Query Frame = 1
Query: 1405 FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNL--NDSCKIRIIVLDVNDNIPEIST-SYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN-EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTP 2427
DRE + YSV V+ +D I + I D ND P F + + +ISE++ + + V A D DS N+ +TYSI+ + +F I+ N GQI +++ LD EV + V+A+DNG+P L D + I + D NDN P SY+F I E K G + A+D D G+N + + V G + G+IDRE+ +V V D+G+ PR V ++V DVNDN+P F NY + I++ + G+ + V A DED G N I Y++ + N + +F I+ DG I+L LD ++ + L + A D G P
Sbjct: 16 LDRESNASYSVTVMASDGKFQAFLE---IDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIV---DGNSSFSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVA---KGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIF-----RPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDSGNK-ESIFDIE-DGTIVLNGTLDREVMDQYTLGILATDNGEP 346 HSP 5 Score: 78.5666 bits (192), Expect = 5.732e-15 Identity = 94/353 (26.63%), Postives = 147/353 (41.64%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD-GEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKAS-RYSVEVICNDNGTPTMSSSEIITIFIS 1506
+ I I D NDN P F I E+VA+ + F A D DS G SI F + + I L V+GD+DRE + F + +D G + G + V++ DVNDN P + Y ISE T+ K++ ++A D+D IG +S N E IF I + + LN G L ++ ++ ++A D GE + + + I+D ND+ P S+ I E+ V + +D+D G N+ + N K++F +N G D E A+ R+ +V DNG P + S + I ++
Sbjct: 146 VTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADS---GKNAKLSYSIPDEDVRKTFAV----DEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDED----IGPNALITYHIDSGNKE---SIFDIEDGTIVLN-GTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQ-------------YFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEIMVT 470 HSP 6 Score: 63.929 bits (154), Expect = 2.113e-10 Identity = 59/212 (27.83%), Postives = 94/212 (44.34%), Query Frame = 1
Query: 340 RHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQ------IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCR----IIVEITDVNDNTPQWVGLPYRKEISECTT-EAKVLQLNAQDKD 942
R +VD+ G++ V IDRE TG + ++ DH + +++ D+NDN P F+P T++I E + ++ A D D G I S E+ F++ D +N G LDRE + + + A+D G R +++ I D+NDN P++ Y ISE T+ +VL + A DKD
Sbjct: 205 RKTFAVDEITGNLSVVGDIDRER---------TGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDED---IGPNALITYHIDSGNKESIFDIEDGTIVLN------GTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKD 398
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO30364 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T100]) HSP 1 Score: 167.162 bits (422), Expect = 1.129e-41 Identity = 189/670 (28.21%), Postives = 291/670 (43.43%), Query Frame = 1
Query: 355 VDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGK-CRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIG--GQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY---NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI 2331
V + GDI V S +DRE I L N + A ++ I + D+ D+ P F T+K+ EN + + + A D+D + SI++ F + +N+ +R + +LDREN+ +E + A D +++V++ DVNDN P + Y E E + E +LQ+ A D D IG + + I EN +Y V + IT ++ L L E + + A D S +T + IK D ND+ PV ++EN+ + V +T +D+D G N++ S L+ L + + + G LN RE+ Y++ + D+ + + I ++D ND+ P F FS+ ED K+GH +G V D D + N + Y I F +N G I LDRE Y + AKD+G P L + + I + DVNDN P S S Y+ + ES + + + ++ A+D D G NG F +++ + T D Y N G I +D EK ++ V D G PP T V I V DV+DN P F P +A Y N+T G V V ATD D + +Y +T +F I
Sbjct: 1137 VSRSTGDIIVDSPLDREFKNVYI---LNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKD-----IGDTISYSIANGDPYGLFTI----DNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDAD----IGDNAAVLYSIVENVTDY---VTVNAIT-GVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGV----LYTRFAIDPDTGNITTREPLN--------REETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRY-YISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQ---VVQVIATDPDEGANGQFTYKITAGDT--DDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVT----RGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLI 1764 HSP 2 Score: 143.665 bits (361), Expect = 1.628e-34 Identity = 193/789 (24.46%), Postives = 325/789 (41.19%), Query Frame = 1
Query: 250 IKLIQNQTKSTEILKTKSFQLESEKSNTYG------RHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIG----DLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIG------------ALKSFKENKASIVVIAADGEGRSNETT--IELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLN-----SIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDI-GQNGTFRFRVRSRSTPIDIQVYNEGKIIYF-----GNIDREXXXXXXXXXXXXXNGN-PPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYL-NITDDMA--AGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSF 2484
+KL +N + T + K + + + +Y L ++D G+I + +DRE + Q +N + + ++ +++ D+NDN P F TI+ E + A D D ++ SI EN + + +N VI LDRE + F F + A+D G + +++ D+NDN+P + Y + E VL + A DKD + N+ ++ Y+ +LY L + ++ + A D R+ E T + + + D NDH P + ++E+ K V R+ TDED +ND V Y S +G +F +N DRE+ + Y++ + D+G P + S+ + I I D NDN P F ++ E + ++ VIA D D N TY I + + F I+ N G I + LD E Y TV A+D G P L +C + I V DV+DN P YS ++ E+ R H ++ +NA+D D + +R+ S +T + + +I G ++RE + ++ V I N + + I VLDVNDN P+F ++ +Y+ ++ +D + + VKA D D G +G II+ + + N G + + LD + + LVV A D+G P+LS++ T+ I D+
Sbjct: 1199 VKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLV----SDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDAD-------IGDNAAVLYSIVENVTDYV----TVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKD------------VGTNA-------KLSYVLSGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDED----------INDNARVR---YYIS---SGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAG-DTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGH---HVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRF-----DSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNL 1928 HSP 3 Score: 138.658 bits (348), Expect = 6.133e-33 Identity = 165/638 (25.86%), Postives = 275/638 (43.10%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPY----RKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLN----KILDREVKDRYEFTVEAKDNGEPNLNDSCKIR---IIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE-GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPL----LNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTK 2316
+ I+++DINDN P F + + EN + + A D+D G +S +Y + D GN + L+RE S+ L A D +G R+I+ +TD ND+ PQ+ Y R+++ T +V + D+ ++R+ IS + + +F + E+ ++ + ++N + ++I A G + T++ + I+D ND++P+ ++ ++E+ K V ++ TD D+G N +F T + G +F +++ GL D EK S Y++ V D GTP ++ + + I +SD +DN P F + + E+ GH + V A D D+ ++ Y I F I +G I LN L+RE RYE V A NL + + I VLDVNDN P S SY ++E I + A D D G++G F + S + Q+ N+ G + +DRE ++V D G P +++ TV+I VLD+NDN P P+ ++ +++ AG VG V A +D I Y +TN K
Sbjct: 1385 VAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKD---VGTNAKLSYVLSGVLYTRFAIDPDTGN-----ITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDN-----ARVRYYISSGNTSL-----MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQF----------------TYKITAGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAI--SRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLED-TGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAA--QDLDTKNLIYYYITNTEEQK 1983 HSP 4 Score: 132.494 bits (332), Expect = 5.034e-31 Identity = 171/667 (25.64%), Postives = 302/667 (45.28%), Query Frame = 1
Query: 508 INDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGD------LDRENIKSFEFHLYASD--GGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYL------NIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSE--FSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHF-ETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNE--GKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSA 2439
IND P F+ + + E+ +R A DRD G+ S + + + Y R GD LDRE + ++ A++ G ++ + +TDV D+ P + ++SE + V ++ A DKD IG I + I+ N Y + I +T I + N+ + F + K S+ ++ S+ + ++++D ND+ PV + +++ E + ++ D D G N+ +S N T++V+++++ T + G + DRE ++ + D+G P+ SS+ + I + D NDN P F T++ + + E+ G + +V A D D N ++Y + G + F I+ + G I + L+RE Y T+ A D+ + ++ I V D ND++P+ + S Y+F + E + H +G++ +D DI N R+ + S +T + V NE G I +DRE+ +++ D+G P + T+V I + DVNDN+P F+ + N + + + + + V +V ATD D G NG Y +T T D+F I ++ G I +K KLD + + L V A+D GTP L+
Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDE---GINAIIFYSSNGAEAKFYVS------------RSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKD----IGDTISYSIA-NGDPYGLFT-IDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLV-------SDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAI-TGVISLGSSQ------------LDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAY-VRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYTR--FAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHT---VGRVATTDEDINDNARVRYYISSGNTSLMFSV-NETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYN----VTLRESVFLKTQVVQVIATDPDEGANGQFTYKIT-AGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTG 1695 HSP 5 Score: 127.872 bits (320), Expect = 1.224e-29 Identity = 179/688 (26.02%), Postives = 284/688 (41.28%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG---NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKEN-----EKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY------FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVI---AKDSDSSPNNIITYSIIGDYEVKETFGINH-NGQIHLNKILDREVKD---------RYEFTVEAKDNGEP---NLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNY-LNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS-DGQXXXXXXXXXXXXNPDRLVVEARDQGTPS 2430
+ + +I++NDN P F + E + + + A D D +G Y L+ ++ YF + N N + LD + ++ ++F L DGGG + V + DVNDN P++ G+PY +I+E V Q+ A DKD + G++ F IS F I S L L ++ V A D S ++L + D ND+ P I + L I N +L++ I D D G N + + S+ +GG + F LNS G DRE Y + + DNG+P ++S + + I D NDN P F+ T+ I+ D G +I A D D+ N + YS+ GD F ++ G++ + K LDRE R+ + A D P + + ++ I V D NDN P+ S +Y ++ E+ + +++A+D+D+ G + + +V K++ N ++ ++ T V I V DVNDN P F N Y ++ ++ G+ V V A+D D G NG I Y LTN N D FSI + G+I + +D + + L V+A DQG PS
Sbjct: 375 VTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQAA----YFSV----NADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGE--NGRLSFNISAGDDGGH-----FSINGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQI---TDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSM-----------------SGGDSR-FTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH--GFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSN---VIQVSATDQDLEYKGKVIYNITDGDENRKCEVE---KLVRHYNWHKKNCVLCKESKCSVER--------TYVVIYVDDVNDNDPVF-----NQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNK-DDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPS 1004 HSP 6 Score: 122.094 bits (305), Expect = 6.593e-28 Identity = 113/408 (27.70%), Postives = 178/408 (43.63%), Query Frame = 1
Query: 1117 EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSS-EIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKF-TYPLLNAHNYLNITDDMAAGSI---VGEVKATDEDFGLNGSIIYNLTNQNH 2310
E S ++ L + + ND++P+ S + + E + IT TD D G + L GGQ F +N+ G D + +Y ++ D G + +T+ + D NDN P F T I+E+ G + V A D DS N ++++I + F IN +G + + LDRE Y TV A D+G + + ++ + VLD NDN P+I+ + S + + A D D G NG + + + + I +DRE D D++++V DNG+PP T +TTVH+ +LDVNDN P F P + Y+ IT D G+I + ++ ATD D NG + Y+L+ H
Sbjct: 367 EKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELR-----------------GGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGH-FSINGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYV-ITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH 755 HSP 7 Score: 108.227 bits (269), Expect = 1.322e-23 Identity = 142/570 (24.91%), Postives = 222/570 (38.95%), Query Frame = 1
Query: 199 YLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECT-TEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDED-QGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEI-ITIFISDENDNPPHFETEFKTFSISEDAK--IGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVE 1878
Y V ENQ P G + ++ K S+ L Y R ++D G+I ++REE S LT ++ I A + I + D ND+ P F + E+V D D + I L+ N + LDRE S+ + A D G + +++ I DVNDN P + Y + E + +V+Q+ A D D + GQ +KI+ + +FYI + + I A +++ + ++A G + +E+ + D +D+ PV S ++ EN V + TD D + + + N DSM+ G Q + LN P +RE +RY ++V T S + I + D NDN P F++E S+ ED I V A+D D + I ++I+ E N G + + LDRE Y V A+D GEP L+ S + I VLD+NDN+P + T I E
Sbjct: 1405 YAYVRENQ----PAGTPVLVVTASDKDVGTNAKLSYVLSGV---LYTR--FAIDPDTGNITTREPLNREETG---SYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDED-------INDNARVRYYISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPD--EGANGQFTYKITAGDTD-----DVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGN---TDSMFLI----GEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPE 1941 HSP 8 Score: 95.9005 bits (237), Expect = 7.114e-20 Identity = 152/597 (25.46%), Postives = 249/597 (41.71%), Query Frame = 1
Query: 478 IFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWV-GLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI---GALKSFKENKASIVVIAADGEG-RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKA---------SRYSVEVICNDNGTPT---MSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSII-GD----YEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN-EGKIIYFGNIDREXXXXXXXXXXXXXNGNP-PRTATTTVHIEVLDVNDNRPKFTY 2172
I + + + D+NDN P F T I EN+ + A D+DS + G +IS+ +F + +G+ + R +LDRE I ++ + A D G ++ V + D NDNTPQ GL ISE VL + D GQ+ + +S F + + L I G + K++ I+ + +G +N TT+ + I D ND+ P + ++ L T + DE G ++ +N T+ + + + +G + F+L+ + G DRE R+ +++ D TP S++ ++I + D NDN P F+++ +SE A+ G + V A D D + Y+I GD EV++ + H N +L +E K E T + I V DVNDN P + S Y+ ++E+ + +++ASDRD G NG +++ + + + N G+I G IDRE V + V D G P R V I V D NDN P+F++
Sbjct: 477 IATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENG---RLSFNISAGDDGGHFSI--NGSGLVTTAR---ELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR-------FTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAF----------DPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEVEKL--VRHYNWHKKNCVLCKESKCSVERTY---------------VVIYVDDVNDNDPVFNQSKYAADVLENSPTGTP---VLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSF 1028 HSP 9 Score: 88.9669 bits (219), Expect = 8.977e-18 Identity = 152/647 (23.49%), Postives = 254/647 (39.26%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEK------TIKIPENVARSSEFSLPV-AKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIK---------SFEFHLYASDGGG-----NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQN----YEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPT--MSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTF---------RFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTN 2301
+ + I+D+NDN P+F P+ I + E ++ + + A D D++ G + S +F L + + L V +LDRE+ + F + A+D R+ + + D NDN+PQ+ Y +SE V+Q++A D+D G++ + I++ +N E +VR + + L KE+K S+ T + + + D ND+ PV + + EN + V R+ +D DQG N + T L NG + F +N++ G DRE + + V D G P+ + +E++ I + DENDN P F I+E++ +G I +V P+ KI ++ R A L + + R I L +ND P S + V E + IG++ A+DRD G N +F V SRST G II +DRE + + V + + TT VHI V DV D++P F L + ++++ + G+ V ++ A D+D G +I Y++ N
Sbjct: 690 VHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANG----KVAYSLSGDEHGFFRL----DPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQD--LEYKGKVIYNITDGDENRKCEVEKLVRHYNWHKKNCVL-------CKESKCSV-----------ERTYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKI----------------TYKLTNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVV-ITVKDENDNFPQFSFTGYEGEIAENSPVGSTITMV--------PD---------------------------QKISSSTLRPRSSPRAPAA------LLTAREKRPITL-INDESPLFEKSMYY--VNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGAEAKFYV-SRST---------GDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLT----VKLSENASIGTNVTKITALDKDIG--DTISYSIAN 1231 HSP 10 Score: 85.5001 bits (210), Expect = 1.144e-16 Identity = 143/603 (23.71%), Postives = 257/603 (42.62%), Query Frame = 1
Query: 763 FEFHLYASD---GGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESI-LYLNIGALKSFKENKASIVVIAADGEG---RSNETTIELEIKDCNDHRPVIKVHSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNI---ITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEF------------------------TVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS-TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGN-PPRTATTTVHIEVLDVNDNRPKFT-YPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPS 2430
+EF +Y D GGG +G + + D NDN P + PY +I+E +L+++A D D Q+++K S N F+ S+ L +G F+ ++ ++V+ A+ G + TT+ +E+ D +D P + S LK I+EN V + D D GIN+ +Y + +G +F ++S G+ D EK + + V ++ P +++ + + + D NDN P F F + ED + + + +D N + + Y ++G + F I+ +G +++NK LD E + + F V + + + + + + +++VNDN P + +SY++ + E +I + A+D D+G G + +R + G I +D + + + + V D G A TV + + DVNDN P+FT P + +I +++ AG+IV +V ATD+D G NG + +N++ + FSI G + ++LD + L V A D G S
Sbjct: 9 YEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDAD--SGTNSQVQYKFS----NATATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRF-LQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPI--------------LY--EIISGNSDGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVG--ADSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEIT---PGTHIADITATDADLGTFGALTYELRGGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTS-----DIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGH-FSINGSGLVTTARELDRETIATYTLTVSAYDHGVSS 577 HSP 11 Score: 70.8626 bits (172), Expect = 3.048e-12 Identity = 100/363 (27.55%), Postives = 159/363 (43.80%), Query Frame = 1
Query: 1513 NDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEI-STSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYN--EGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIY----NLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTV--NKSNGLP 2571
ND P FE ++SE A G IG V A D D N II YS G + F ++ + G I ++ LDRE K+ Y V A + + + ++ I V DV D+ P S+S + K+ E+ + K+ A D+DIG ++ + P + + G+I +DRE V + ++ V D+ N V ++V DVNDN P F+ P + ++ G+ + +VKA D D G N +++Y N+T+ + + S G L ++++ + A D G PS S+T ++ I+ D NS N DY V N+ G P
Sbjct: 1083 NDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNG---AEAKFYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTVKLSENASIGTN---VTKITALDKDIGDTISYSI---ANGDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVV-VQVEDVNDNPPVFSMPGYTIEYW----EESPEGTSILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAITGVISLGSSQLDREVEEYF----NFTIRATDSGVPSKSSTASVAIKLVDIND----------NSPVFNNTDYYAYVRENQPAGTP 1417 HSP 12 Score: 57.7658 bits (138), Expect = 3.183e-8 Identity = 64/209 (30.62%), Postives = 97/209 (46.41%), Query Frame = 1
Query: 1732 VKDRYEFTVEAKDN---GEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFR---VRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQS 2337
++D YEFTV +D+ G S +IV D NDN P + Y KI E+ I K++A D D G N +++ + TP G++ G +D E ++V D G P + TTV IEV D++D P+F L + I ++ GS V V+A D D G+N I+Y + + N + +F+I S
Sbjct: 5 IQDNYEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTT---ILKISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRF----LQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGN-SDGVFTIDS 205
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 270.011 bits (689), Expect = 4.033e-75 Identity = 242/776 (31.19%), Postives = 374/776 (48.20%), Query Frame = 1
Query: 208 VEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISKCLTGAFLNYIIFA-------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
V+E Q PN+ IG+L S + ++LE G + VD K GDI+ T IDRE + C+ + K +L + + ++ E +IE+ DINDN P F TI +PEN + FS+P+A DRDSE+ GV Y L + + ++ D P L V+G+LDRE S++ + A DGG Q + + V +TD NDN+P++ Y E+SE + VLQ+ A D D G+I + + + ++RI T I+Y+ G L + N S V+A D + +S++T + +E+ D ND+ P +++ HS + I E+ V + V+D+D+G N+ +C + L S +N ++K F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN P F +E+ + G I V A D+DS N + Y+I+GD +K F I+ N G++ LDRE K+RYEF V A D G P + + I VLD NDN P+ S YSF ++E+ +G + D D G+N V +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P + ++ ++ + S V V+A D D G N +++++ N + LF I S G+I L K++ K RLVV D+G P AT ++I
Sbjct: 28 VQEEQPPNTLIGSLAA-DHGLPDSGHL-----YKLE------VGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLVKG-KPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSD--MGPNGEIEYSLHQAVDPVPKLLRIDRTT-GIIYVK-GPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDN--KRKYFLQTTTP---LDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVLDMDKGENAHVHLSVEPDGGKFVVQ-NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKP--SNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQ-LFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHI 774 HSP 2 Score: 129.028 bits (323), Expect = 8.819e-30 Identity = 150/586 (25.60%), Postives = 240/586 (40.96%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRS-------RSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L++ + D NDN P F+ ++ EN A D D G +Y L + + ID I + V G LDRE I S F++ A D G K + +E+TD NDN P + +GL E ISE V + DKD+ + + G + F++ S + R +++ T + Y + KE + IV + + S+ ++++++ D ND+ PV + E + + +T TD D G N+E ++ +++ K +F+++ G DRE RY V D G+P + + I + D NDN P F +FS+ E+ +G+V D D N + S+ G + V+ N G I + DRE + Y F ++A D GEP + + I VLD NDN P ++ ++ SF+ + H + + A D D G N F + R +P + G+I + R+ ++V V D G PPR AT VHI V
Sbjct: 230 LRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPK--LLRIDRTTGI---IYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERV------KEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYI---------------KGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDGGKFVVQ-----NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRQLSPVASPDSHVDV--VEAEDLDSGPNADLVFSIAGGNPYQLFRISP------SSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 776 HSP 3 Score: 96.6709 bits (239), Expect = 7.500e-20 Identity = 141/605 (23.31%), Postives = 245/605 (40.50%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH-------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP-----YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESI-LYLNIGALKSF----KENKA--SIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGD--YEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE 1893
S E NSP+G+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI + Y++ D + F + IE+ D NDN P+ + E I E++ + +L D+D + V + F+L ++ + +L+ LD E +K + + A D G + V++TDVNDN+P + + + +E + +L + A D D N++ + IV YI + N G +K+ +E+K V AAD T+ +++ DCND+ P + S + EN V +TV D D+G N+ S+ E G K + Q + + + FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + +V A+D DS PN + +SI G Y++ F I+ +G+I L K + R+ + V D G+P + + + I V + N+ + + +R+
Sbjct: 248 SYEAEVSENSPVGH--SVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEI---------NSLSFYVVARDKGPQPKSSKTF-VTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADS------------GTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSV----------------EPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFR--QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQL---FRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNVSLVEALVGHSLYTPLDRD 801
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 271.166 bits (692), Expect = 2.038e-74 Identity = 242/776 (31.19%), Postives = 374/776 (48.20%), Query Frame = 1
Query: 208 VEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPISKCLTGAFLNYIIFA-------DHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKV-------HSSSLK-IKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQ-SDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
V+E Q PN+ IG+L S + ++LE G + VD K GDI+ T IDRE + C+ + K +L + + ++ E +IE+ DINDN P F TI +PEN + FS+P+A DRDSE+ GV Y L + + ++ D P L V+G+LDRE S++ + A DGG Q + + V +TD NDN+P++ Y E+SE + VLQ+ A D D G+I + + + ++RI T I+Y+ G L + N S V+A D + +S++T + +E+ D ND+ P +++ HS + I E+ V + V+D+D+G N+ +C + L S +N ++K F + P D E+ Y VE++ D+G P +SS+ + + ++D NDN P F +E+ + G I V A D+DS N + Y+I+GD +K F I+ N G++ LDRE K+RYEF V A D G P + + I VLD NDN P+ S YSF ++E+ +G + D D G+N V +Q G I+ + DREK + +D G PPR++ V I VLD NDN P T P + ++ ++ + S V V+A D D G N +++++ N + LF I S G+I L K++ K RLVV D+G P AT ++I
Sbjct: 105 VQEEQPPNTLIGSLAA-DHGLPDSGHL-----YKLE------VGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLVKG-KPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSD--MGPNGEIEYSLHQAVDPVPKLLRIDRTT-GIIYVK-GPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDN--KRKYFLQTTTP---LDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSP---VGMVTVLDMDKGENAHVHLSVEPDGGKFVVQ-NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKP--SNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQ-LFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHI 851 HSP 2 Score: 129.798 bits (325), Expect = 6.316e-30 Identity = 149/583 (25.56%), Postives = 241/583 (41.34%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGN--QGKCRIIVEITDVNDNTP----QWVGLPYRKE----ISE-CTTEAKVLQLNAQDKDDPQ------TIGGQIRFKISENSQNYEMIVRIFYI--TESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPG-----LYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSI---IGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEIS--TSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY----NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEV 2136
L++ + D NDN P F+ ++ EN A D D G +Y L + + ID I + V G LDRE I S F++ A D G K + +E+TD NDN P + +GL E ISE V + DKD+ + + G + F++ S + R +++ T + Y + KE + IV + + S+ ++++++ D ND+ PV + E + + +T TD D G N+E ++ +++ K +F+++ G DRE RY V D G+P + + I + D NDN P F +FS+ E+ +G+V D D N + S+ G + V+ N G I + DRE + Y F ++A D GEP + + I VLD NDN P ++ ++ SF+ + H + + A D D G N F + + Q++ + G+I + R+ ++V V D G PPR AT VHI V
Sbjct: 307 LRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPK--LLRIDRTTGI---IYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERV------KEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYI---------------KGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDGGKFVVQ-----NGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRQLSPVASPDSHVDV--VEAEDLDSGPNADLVFSIAGGNP---YQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 853 HSP 3 Score: 98.2117 bits (243), Expect = 3.730e-20 Identity = 142/603 (23.55%), Postives = 244/603 (40.46%), Query Frame = 1
Query: 205 SVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH-------QIFELQIEIIDINDNFPSFQ--------PDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP-----YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAK-VLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESI-LYLNIGALKSF----KENKA--SIVVIAADGEGRSNETTIELEIK--DCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFE----TEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGIN-HNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE 1893
S E NSP+G+ ++Q + +++ + ++ L+ +D+ G I+V +DREEI + Y++ D + F + IE+ D NDN P+ + E I E++ + +L D+D + V + F+L ++ + +L+ LD E +K + + A D G + V++TDVNDN+P + + + +E + +L + A D D N++ + IV YI + N G +K+ +E+K V AAD ++ T + IK DCND+ P + S + EN V +TV D D+G N+ S+ E G K + Q + + + FDREK S Y+ + D G P SS +TI + DENDN P + F+ +S A + +V A+D DS PN + +SI G + F I+ +G+I L K + R+ + V D G+P + + + I V + N+ + + +R+
Sbjct: 325 SYEAEVSENSPVGH--SVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEI---------NSLSFYVVARDKGPQPKSSKTF-VTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVP------FQLRPASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADS------------GTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSV----------------EPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFR--QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPY-QLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNVSLVEALVGHSLYTPLDRD 878
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 247.284 bits (630), Expect = 3.181e-67 Identity = 244/812 (30.05%), Postives = 376/812 (46.31%), Query Frame = 1
Query: 130 MFKMFWQLFFLYTVV-----KSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPI---SKCLTGAFLNY---------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--------LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
M + W L T+V + S +Y + E Q PN+ IG+L + L + E + Y R VD K G+I+ T IDRE + C+ + KC FL + I ++ E IE++DINDN P F T+ IPEN + FS+PVA DRDS GV +Y L + + ++ + + P + VIG+LDRE S++ ++ DGG + + +TD NDN P++ Y E+ E + VLQ+ A D D G I + + + S + ++RI T I+Y+ G + ++N V+A D +S++ + + IKD ND+ P I++ L I +N + I V + V+D D+G N+ +C + V S N ++K F + D E+ Y +E++ D+G P +SS+ + + ++D NDN P F + +ED + G ++ V+A D+DS N + YSII + F IN N G+I + LDRE +RYEF V A D G P+ + + I V D NDN P+ S YSF + E+ + +G + SD D G+N V + IQ G I+ + DREK + +D G+PPR++ V I VLD NDN P T P +++ +L + + V VKA D D G+N + Y +T N LF I + G+I L + K K RLVV D+G P T +++
Sbjct: 15 MAVLRWGCLVLLTIVLMVPCGAVPSNNIY-KLSEEQPPNTLIGSLAADLG--------LPDSGHLYKLEVGSPYLR----VDSKTGEIYTTEIPIDRETLSDCRNLFEDDKC----FLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDAD--TGANGDIDYSLHQASDTVQRLLRIDRST-GIIYVK-GLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVV--AGDVPFQLRPASESANDRKRKYFLQTTT---LLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSII-ESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNP---VGVVTVSDADKGENSQVTLFVEPDNGKFIIQ-NGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSS--PPDTPVEVVKAEDIDAGVNAELYYTITGGN-PHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHV 792 HSP 2 Score: 133.265 bits (334), Expect = 4.883e-31 Identity = 144/580 (24.83%), Postives = 247/580 (42.59%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTP----QWVGLP----YRKEISE---CTTEAKVLQLNAQDKDDPQTI----GGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGI-NHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDN 2154
L+I + D NDN P F+ ++ ++PEN A D D+ G Y L S ++ ID I + V G +DRE +F++ A D G N K ++ + I D NDN P + +GL + ISE T ++Q++ +D+ + + G + F++ S++ R +++ + L + K+ + IV + + S+ ++++++ D ND+ P + E+ + V + TD D G+N+E S+ +++ SL F++NS G DRE RY V D G P+ + + I+ I + D NDN P F +FS++E+ + +G+V D+D N+ +T + D F I N G I + DRE + Y F ++A D G+P + + I VLD NDN P ++ + + + A D D G N + + + Q+ +N G+I + ++V V D G PPR T VH+ V + +N
Sbjct: 249 LRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQR--LLRIDRSTGI---IYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLL----DYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASL----------------FEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPD---NGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNETTNN 800 HSP 3 Score: 97.0561 bits (240), Expect = 7.372e-20 Identity = 96/349 (27.51%), Postives = 159/349 (45.56%), Query Frame = 1
Query: 1495 IFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-------GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPID--IQVYNEGKIIYF-GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYL-NITDDMAAGSIVGEVKATDEDFGLN--------GSIIYNLT----NQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
I + D NDN P F + T SI E+ G I +A D DS N + Y++ + + FG+ Q+ + LDRE KD Y+ + D G+P S +RI V D NDN P+ + Y ++ E+ H + ++ A+D D G NG + + S + +++ IIY G +DRE+ + + V D G +++ V I + D NDN P L+ N++ NI++DM G+ V V+ +D D G N G + + L + N K + +Q+ + ++ D R+ + A D G P+LS+T +L ++
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHS---VLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDY------RIEIVAVDSGNPALSSTNSLKVQ 478 HSP 4 Score: 91.6633 bits (226), Expect = 3.315e-18 Identity = 141/586 (24.06%), Postives = 237/586 (40.44%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQPDEKTIKIPEN-VARSSE---FSLPVA----KDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP-----YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKT--FSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE 1893
NSP G+ + ++ T + L + S+T R L+ +D+ G I+V +DREE Y++ D ++ I I D NDN P+ + + I +N VA SE PVA DRD + V + F+L + N +L+ LD E IK + + A D G + V++TD+NDNTP + +E KV+ + A D D + ++ + I E+S +F I + + + L + V AAD ++ + + ++D ND+ P + S + EN V +TV+D D+G NS+ + ++ P +NG K I Q + + + FDREK S Y+ + D G P SS +TI + DENDN P+ + + + + +V A+D D+ N + Y+I G F I+HN G+I L + + K + V D G+P + + + + V + +N+ I + +R+
Sbjct: 275 NSPPGHSVLQVRANDADTGANGDIDYSLH-QASDTVQR-LLRIDRSTGIIYVKGLVDREE---------DNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVP------FQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDAD--SGVNAELVYSIIESSA-----ASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVT-------------LFVEP-DNG--KFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGG-NPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNETTNNVTLIEGLVGHSLYTPLDRD 819
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 246.899 bits (629), Expect = 1.186e-66 Identity = 244/812 (30.05%), Postives = 378/812 (46.55%), Query Frame = 1
Query: 130 MFKMFWQLFFLYTVV-----KSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTS-AIDREEI--CQPI---SKCLTGAFLNY---------IIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAAD--GEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKI--------LVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
M + W L T+V + S +Y + E Q PN+ IG+L + S + ++LE G + VD K G+I+ T IDRE + C+ + KC FL + I ++ E IE++DINDN P F T+ IPEN + FS+PVA DRDS GV +Y L + + ++ + + P + VIG+LDRE S++ ++ DGG + + +TD NDN P++ Y E+ E + VLQ+ A D D G I + + + S + ++RI T I+Y+ G + ++N V+A D +S++ + + IKD ND+ P I++ L I +N + I V + V+D D+G N+ +C + V S N ++K F + D E+ Y +E++ D+G P +SS+ + + ++D NDN P F + +ED + G ++ V+A D+DS N + YSII + F IN N G+I + LDRE +RYEF V A D G P+ + + I V D NDN P+ S YSF + E+ + +G + SD D G+N V + IQ G I+ + DREK + +D G+PPR++ V I VLD NDN P T P +++ +L + + V VKA D D G+N + Y +T N LF I + G+I L + K K RLVV D+G P T +++
Sbjct: 15 MAVLRWGCLVLLTIVLMVPCGAVPSNNIY-KLSEEQPPNTLIGSLAADL-GLPDSGHL-----YKLE------VGSPYLRVDSKTGEIYTTEIPIDRETLSDCRNLFEDDKC----FLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDAD--TGANGDIDYSLHQASDTVQRLLRIDRST-GIIYVK-GLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVV--AGDVPFQLRPASESANDRKRKYFLQTTT---LLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSII-ESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNP---VGVVTVSDADKGENSQVTLFVEPDNGKFIIQ-NGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSS--PPDTPVEVVKAEDIDAGVNAELYYTITGGN-PHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHV 792 HSP 2 Score: 132.88 bits (333), Expect = 7.070e-31 Identity = 144/580 (24.83%), Postives = 247/580 (42.59%), Query Frame = 1
Query: 487 LQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQ--GKCRIIVEITDVNDNTP----QWVGLP----YRKEISE---CTTEAKVLQLNAQDKDDPQTI----GGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLY-----FDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGI-NHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQV-YNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDN 2154
L+I + D NDN P F+ ++ ++PEN A D D+ G Y L S ++ ID I + V G +DRE +F++ A D G N K ++ + I D NDN P + +GL + ISE T ++Q++ +D+ + + G + F++ S++ R +++ + L + K+ + IV + + S+ ++++++ D ND+ P + E+ + V + TD D G+N+E S+ +++ SL F++NS G DRE RY V D G P+ + + I+ I + D NDN P F +FS++E+ + +G+V D+D N+ +T + D F I N G I + DRE + Y F ++A D G+P + + I VLD NDN P ++ + + + A D D G N + + + Q+ +N G+I + ++V V D G PPR T VH+ V + +N
Sbjct: 249 LRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQR--LLRIDRSTGI---IYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLL----DYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASL----------------FEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPD---NGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNETTNN 800 HSP 3 Score: 96.6709 bits (239), Expect = 8.348e-20 Identity = 96/349 (27.51%), Postives = 159/349 (45.56%), Query Frame = 1
Query: 1495 IFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-------GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTS-YSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPID--IQVYNEGKIIYF-GNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKF---TYPLLNAHNYL-NITDDMAAGSIVGEVKATDEDFGLN--------GSIIYNLT----NQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIR 2460
I + D NDN P F + T SI E+ G I +A D DS N + Y++ + + FG+ Q+ + LDRE KD Y+ + D G+P S +RI V D NDN P+ + Y ++ E+ H + ++ A+D D G NG + + S + +++ IIY G +DRE+ + + V D G +++ V I + D NDN P L+ N++ NI++DM G+ V V+ +D D G N G + + L + N K + +Q+ + ++ D R+ + A D G P+LS+T +L ++
Sbjct: 139 IEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHS---VLQVRANDADTGANGDIDYSLHQASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDY------RIEIVAVDSGNPALSSTNSLKVQ 478 HSP 4 Score: 91.2781 bits (225), Expect = 4.839e-18 Identity = 144/586 (24.57%), Postives = 236/586 (40.27%), Query Frame = 1
Query: 229 NSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADH------QIFELQIEIIDINDNFPSFQPDEKTIKIPEN-VARSSE---FSLPVA----KDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINP-----YLRVIGDLDRENIKSFEFHLYASDGG--GNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEA-KVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNI-GALKSFKENKASIVVIAADG--EGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNS---IPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKT--FSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHN-GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWERE 1893
NSP G+ + ++ T + L + S+T R L+ +D+ G I+V +DREE Y++ D ++ I I D NDN P+ + + I +N VA SE PVA DRD + V + F+L + N +L+ LD E IK + + A D G + V++TD+NDNTP + +E KV+ + A D D + ++ + I E+S +F I + + + L + V AAD ++ + + ++D ND+ P + S + EN V +TV+D D+G NS+ T FV D NG K I Q + + + FDREK S Y+ + D G P SS +TI + DENDN P+ + + + + +V A+D D+ N + Y+I G F I+HN G+I L + + K + V D G+P + + + + V + +N+ I + +R+
Sbjct: 275 NSPPGHSVLQVRANDADTGANGDIDYSLH-QASDTVQR-LLRIDRSTGIIYVKGLVDREE---------DNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVP------FQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDAD--SGVNAELVYSIIESSA-----ASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQV------TLFVEPD--------NG--KFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGG-NPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNETTNNVTLIEGLVGHSLYTPLDRD 819
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: ENSORLT00000005228.2 (pep primary_assembly:ASM223467v1:10:15165018:15172306:-1 gene:ENSORLG00000004176.2 transcript:ENSORLT00000005228.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 226.483 bits (576), Expect = 3.811e-61 Identity = 194/648 (29.94%), Postives = 302/648 (46.60%), Query Frame = 1
Query: 82 INHLTVRNNL*ILFGLMFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDH--GNNINPYLRVIGDLDRENIKSFEFHLYASDGGG--NQGKCRIIVEITDVNDNTPQWVGLPYRKEISE-CTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGR---SNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCS-LNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIG--DYEVKETFGINHN---GQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWE----REHKHFYIGKLNASDRDIGQNGTFRFRV 1971
IN V++ L +LF + L SV+L SV E P + +GN+ K + + + + L+T+ FQ+ + K + ++ K G ++V IDREE+C +C + +I +++ ++IEI D+ND+ PSF +T+ I EN F+L A D D K GV S YF L+ H GN I+P L + LDRE + E L A DGG G I + + D NDN P + Y+ +I E +K+ LN D DD G S S++ + I+ F I +++ ++E KA + A +G+ S + + +E+ D ND+ P I V S + E+ + ++V D+D G N E C LND F LD+ Y K + L + DRE S+Y+V ++ +D G P S+ ++T+++SD NDN PHF + F + ++E+ K G IG V A D+D N ITYS++ + T I+ N G+I K D E ++F V+A D+G P L+ + + I VLD NDN P I YS + E +++ K+ A D D G N + +
Sbjct: 1 INTPVVQSGLQLLFTCL------ALALLDCNSGAASVQLAYSVSEEVNPETNVGNIAK---DLSLNVQDLETRLFQIVASK-----KKYFEINLKTGFLFVNERIDREELCAEEPRC--SVTVEAVINNPLKLYRVEIEIKDVNDHSPSFNTKLQTLDIAENTIPGFRFALSEANDADVGKNGV------SAYKLSQNEYFNLVTHKRGNTISPELVLQKALDREKKANIELLLTAVDGGSPPKSGTSEININVLDSNDNAPIFSSSLYKIQILENVAVGSKIFTLNVTDADD----GTNSEIVYSLRSKDQDHILDAFQIDPETGIISVKGKIDYEERKAFEIRAEARDKGQPPMSAHSKVLVEVIDVNDNTPEITVTSLLSTLNEDADVGTAIALVSVLDQDSGKNGEVKCEILNDVPF-RLDTNY---------KNYYSL--VVNGKLDREVTSKYNVTILVSDEGRPARSNISVVTVYLSDVNDNAPHFPSPFISIYVNENGKTGGVIGKVSAIDADVDTNAKITYSVLATNTSSLLLTTMISANPETGEITSLKSFDYEELKTFQFKVQATDSGVPPLSSNVTVNIFVLDENDNSPSILAPYSEHGSVNSENIPYSAEAGYFVAKIRAVDADSGYNALLSYHL 610 HSP 2 Score: 145.976 bits (367), Expect = 3.173e-35 Identity = 156/562 (27.76%), Postives = 251/562 (44.66%), Query Frame = 1
Query: 814 RIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLN-AQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEG--RSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSL--NDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVY------NEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLL--NAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSI-QSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYI 2457
R+ +EI DVND++P + +I+E T L+ A D D + G +K+S+N + + ++ T S + AL K+ +++ A DG +S + I + + D ND+ P+ ++I EN + + VTD D G NSE SL D + + LD+ P E G + S+ G D E+ + + D G P MS+ + + + D NDN P +++EDA +G I +V D DS N + I+ D + + + +N LDREV +Y T+ D G P ++ + + + DVNDN P + + V E IGK++A D D+ N + V + +T + G+I + D E++ V D+G PP ++ TV+I VLD NDN P P + N NI AG V +++A D D G N + Y+L+ + +LF I S G+I K+++ L+V D G PSLSAT ++ +
Sbjct: 119 RVEIEIKDVNDHSPSFNTKLQTLDIAENTIPGFRFALSEANDADVGK--NGVSAYKLSQN-EYFNLVTHKRGNTISPELVLQKALDREKKANIELLLTAVDGGSPPKSGTSEININVLDSNDNAPIFSSSLYKIQILENVAVGSKIFTLNVTDADDGTNSEIVYSLRSKDQDHI-LDAFQIDP-ETG-------IISVKG-KIDYEERKAFEIRAEARDKGQPPMSAHSKVLVEVIDVNDNTPEITVTSLLSTLNEDADVGTAIALVSVLDQDSGKNGEVKCEILNDVPFRLDTNYKNYYSLVVNGKLDREVTSKYNVTILVSDEGRPARSNISVVTVYLSDVNDNAPHFPSPFISIYVN--ENGKTGGVIGKVSAIDADVDTNAKITYSVLATNTSSLLLTTMISANPETGEITSLKSFDYEELKTFQFKVQATDSGVPPLSSNVTVNIFVLDENDNSPSILAPYSEHGSVNSENIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS-EPKGNNLFRIGTSSGEIRTKRRMSDNDLKSHPLLVLVSDNGEPSLSATVSIEV 664 HSP 3 Score: 84.7297 bits (208), Expect = 4.062e-16 Identity = 85/283 (30.04%), Postives = 146/283 (51.59%), Query Frame = 1
Query: 1669 KETFGIN-HNGQIHLNKILDREV----KDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEG-----KIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNL--TNQNHTKDLFSIQSD-GQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRD 2478
K+ F IN G + +N+ +DRE + R TVEA N L ++ I + DVND+ P +T + ++ E F A+D D+G+NG +++ S++ ++ + G +++ +DREK I++L+ +D G+PP++ T+ ++I VLD NDN P F+ L + I +++A GS + + TD D G N I+Y+L +Q+H D F I + G I +K K+D + + + EARD+G P +SA + + + D
Sbjct: 73 KKYFEINLKTGFLFVNERIDREELCAEEPRCSVTVEAVINNPLKL---YRVEIEIKDVNDHSPSFNTK--LQTLDIAENTIPGFRFALSEANDADVGKNGVSAYKL-SQNEYFNLVTHKRGNTISPELVLQKALDREKKANIELLLTAVDGGSPPKSGTSEININVLDSNDNAPIFSSSLYK----IQILENVAVGSKIFTLNVTDADDGTNSEIVYSLRSKDQDHILDAFQIDPETGIISVKGKIDYEERKAFEIRAEARDKGQPPMSAHSKVLVEVIDVND 345
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000059440.1 (SMESG000059440.1) HSP 1 Score: 2010.73 bits (5208), Expect = 0.000e+0 Identity = 1046/1047 (99.90%), Postives = 1046/1047 (99.90%), Query Frame = 1
Query: 130 MFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAXXXXXXXXXXXXXXXXXXXXTIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPVAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 3270
MFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGI IYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPVAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV
Sbjct: 1 MFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGIAIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPVAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 1047
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000059440.1 (SMESG000059440.1) HSP 1 Score: 1985.3 bits (5142), Expect = 0.000e+0 Identity = 1042/1080 (96.48%), Postives = 1043/1080 (96.57%), Query Frame = 1
Query: 139 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAXXXXXXXXXXXXXXXXXXXXTIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNP------------------------------------VAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 3270
MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGI IYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNP +AIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV
Sbjct: 1 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGIAIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPGNQFSNRSKWSNLTMRPFLNSFMFIYIVLFMLYDDNMAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 1080
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000059440.1 (SMESG000059440.1) HSP 1 Score: 1984.53 bits (5140), Expect = 0.000e+0 Identity = 1043/1082 (96.40%), Postives = 1043/1082 (96.40%), Query Frame = 1
Query: 139 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAXXXXXXXXXXXXXXXXXXXXTIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPV--------------------------------------AIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 3270
MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGI IYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPV AIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV
Sbjct: 1 MFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVKKYYLKSISSSIYENYFELIDHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRVRSRSTPIDIQVYNEGKIIYFGNIDREKVDKIDVLVDVIDNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQIILKKKLDTKIKNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSKYINPKDYPRTVNKSNGLPNNAIILVLLVVSIMMIVIVVGGIAIYIYCRGKGLSRLGDNNKHLSTNRDSNNVIYQKGCSKSVPKAENQINDTYNPVLGNQFSNRSKWSNLTMRPFLNSFMFIYIVLFMLYDDNMAIGTFQPYYTNLMLLKNNCFPPIDNSYQISQTMLTDNYFSFQPKSNTPTPDKENQEFSAFNSMESWNPSKHQTSNLTMQARKKTFSENSDNFYETEPDHKYAFIHPSSITNLDMNHELNNIGHFTTPSQSRRNDFIQSRSDSNQKVKINLVNSSFV 1082
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000009208.1 (SMESG000009208.1) HSP 1 Score: 458.759 bits (1179), Expect = 8.092e-144 Identity = 276/727 (37.96%), Postives = 431/727 (59.28%), Query Frame = 1
Query: 349 ISVDQKKGDIWVTSAIDREEICQPISKCLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKI--PENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXEN----YFELI---DHGNNINPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSFKENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYT---SPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFRV----RSRSTPIDIQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDLFSIQSDGQXXXXXXXXXXXXNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDS 2481
+ ++++ GDI + S DREE+C + +++I+ E + I D+NDN P F+ K I I EN A+ + LP A D DS + G+ +Y +K + +S + YF+L+ D N I P L V+ LDRE ++ F F+L A D G+C+I + + D+NDN+P W Y EI EC+ + ++L+L A D DDP T G++ ++ISE S++ + I +F+IT ++L+++I ++ + I ++A DG G+S+ TI ++I DCN+++P I++ + +I E E +T + V+D D+G+N+EF C ++D+ L SM + SPL G+ ++ LN+ G+ F+REK + S+ + C D G P S+++I+TI + D NDN P F TFS+ E+ IG + V A D+D + N ++Y I+ D K+ F IN+ GQI N LDRE D YEF V AKD+G+ +++ SC ++I VLDVND PE+ + F+I ES H +GK+NA+D D G NGT F++ + +Q+ ++G++ +GN+DRE I + V DNG PP ++TTTV I +LDVNDN+PKF++P ++ +N++N++ + SI+G V+ATD D G NGSI Y L K F +Q GQ+IL K L K NPDRL+++A D G PSL+ TLY+RY+ + S
Sbjct: 13 LEINRRTGDIIIKSIFDREEVCPYLET--DDCKVDFILLYQTTPKEFSLYIKDVNDNSPVFKEKSKQISIHEGENSAQM-KHHLPKAVDLDSSENGIDRYTIKFVDNSKSDENFHEYFKLVNQKDKDNIITPVLHVMKLLDREKVERFSFNLIAWDKKQKSGECKISIIVLDINDNSPIWSNTQYSVEIKECSLQREILKLEAYDLDDPNTENGRVTYEISEKSKSNDKISSLFHITSNMLFVDIMKIRDIESYDFEIEILAKDGSGKSSSKTIYIKILDCNNNKPNIEISQRNPRIFEKEVRSTKLTNVIVSDPDRGVNAEFDCVIDDSLHFQLKSMMSKKISPL--SGRWVLYSLNTSEGVEFNREKQASLSIVITCTDKGLPAQSNTQILTIHVLDINDNKPEFTRHMYTFSVEENIPIGSVVASVKAIDADINENGRVSYEIVSD--PKDMFSINNKGQIQTNNDLDREKVDMYEFQVIAKDHGKESMSSSCTVKIFVLDVNDCKPEVDKQFVFEITESHGYTTIHKNLGKINATDADFGLNGTINFKISHIQQQNQRKNLLQITSDGQLSIYGNVDREVTKSIHTEIIVSDNGRPPLSSTTTVVINILDVNDNKPKFSFPNIHNNNHINLSLQSSVNSILGVVEATDPDNGNNGSITYKLLGGELIKSTFELQQSGQLILIKSLLDKRLNPDRLMIQASDSGNPSLTEMATLYLRYYNNKKS 732
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000066775.1 (SMESG000066775.1) HSP 1 Score: 457.988 bits (1177), Expect = 1.397e-142 Identity = 303/828 (36.59%), Postives = 454/828 (54.83%), Query Frame = 1
Query: 139 MFWQLFFLYTV-VKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSTEILKTKSFQLESEKSNTYGRHLISVDQKKGDIWVTSAIDREEICQPISK-CLTGAFLNYIIFADHQIFELQIEIIDINDNFPSFQPDEKTIKIPENVARSSEFSLPVAKDRDSEKYGVXXXXXXXXXXXXXENYFELIDHGNN---------------INPYLRVIGDLDRENIKSFEFHLYASDGGGNQGKCRIIVEITDVNDNTPQWVGLPYRKEISECTTEAKVLQLNAQDKDDPQTIGGQIRFKISENSQNYEMIVRIFYITESILYLNIGALKSF-KENKASIVVIAADGEGRSNETTIELEIKDCNDHRPVIKVHSSSLKIKENEKSKILVTRITVTDEDQGINSEFSCSLNDTNFVSLDSMYTSPLENGGQKKIFQLNSIPGLYFDREKASRYSVEVICNDNGTPTMSSSEIITIFISDENDNPPHFETEFKTFSISEDAKIGHEIGIVIAKDSDSSPNNIITYSIIGDYEVKETFGINHNGQIHLNKILDREVKDRYEFTVEAKDNGEPNLNDSCKIRIIVLDVNDNIPEISTSYSFKIVESWEREHKHFYIGKLNASDRDIGQNGTFRFR---VRSRSTPID----------IQVYNEGKIIYFGNIDREXXXXXXXXXXXXXNGNPPRTATTTVHIEVLDVNDNRPKFTYPLLNAHNYLNITDDMAAGSIVGEVKATDEDFGLNGSIIYNLTNQNHTKDL-FSIQSDGQXXXXXXXXXXX---XNPDRLVVEARDQGTPSLSATTTLYIRYFKPRDSFDRSNENSMNSK 2517
MF +L L +K ++ + SV+EN + +GN+ + S+ +S +++ + ++Y S+++ GD+ V S +DRE IC+ + C +L+ D ++ IEI DINDN P FQ +K I I EN+ + + LPVA+D+DS KYGVK YY+ EN + I GNN I P L +I ++DRE SF F L A+D G G C + V +TDVNDN P+W Y+ I EC +E +L+L A D+DDP T G + +++S+ +++ +++ +IFYI + L+L + N I + A DG GR NET++++ I+DCNDH PVI + + K+ EN+K KI++T + V DED+G N F CSLND+ ++L + + I+++ + P FDREK S Y+VE+ C D G P MSS + +I I D NDN P F + K F + E+ IG +G V A D DSS N I YSI+ + F I+ G+I DRE D YEF V A+DNGEP LNDS +++ + D+ND P Y F+I ES+ K+ + ++ A+D+D+GQNGT ++R V+ P + I+V +G I +GN+DRE++ I +LV D+G P + TTT+ IEVLD+NDN P F +P N N++N++ + G + VK D D G+NG+I ++L N N ++ F IQS+G+II+ + PDRL+++A D G + TLYIRY S SN S+ K
Sbjct: 1 MFIELDILIIFSIKLVITLNVEFSVDENCRIGHVVGNVYSKLNQLPNSS-----RSSLMKANEKDSY----FSLNRTSGDLIVKSFLDRETICENTKETCSMKLYLD----QDTHAIQIVIEINDINDNVPVFQTTQKVINIQENIPIGTTYPLPVAQDKDSYKYGVKTYYIARCQGIDQENQVKTI--GNNFQFFQIKNPKSKQEEIYPSLEIIKNIDREEFVSFVFILIAADFGNQTGSCTVTVLVTDVNDNAPEWTKDNYKVNIQECQSEGDILELIANDRDDPNTKNGLVSYQLSDRTEDRKIVSQIFYINGNKLHLTNNRISGLINRNNIRIYITATDGNGRMNETSVDIAIEDCNDHPPVISIANRFGKVLENQKQKIILTTVQVKDEDKGRNGMFECSLNDSGKLNLKN-----IRFDDNFAIYKIETYPDTSFDREKISVYTVEIKCVDQGNPAMSSMQKFSINIIDVNDNAPRFVNKIKMFHVVENNPIGSTVGQVRAMDLDSSNNGHIVYSILNS---NDNFAISIYGEIQSKIKFDREKTDSYEFVVTARDNGEPQLNDSMVVKVKIQDINDCTPVFEKDYFFRITESYGESIKNERLEQIKATDKDLGQNGTVKYRLIDVKPIGIPGNSKLKAELRNLIKVSFDGAISIYGNLDREEISSIQLLVQAFDDGYPSLSTTTTIIIEVLDLNDNAPVFLFP-SNNMNFVNVSVEWEIGKTICTVKTKDLDQGINGTITHSLINSNKRENFPFKIQSEGEIIIAHSMKEFSNFRSLPDRLIIKASDLGQNPKNNIATLYIRYIH---SLTNSNPTSIGKK 801 The following BLAST results are available for this feature:
BLAST of Protocadherin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033622 ID=SMED30033622|Name=Protocadherin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3448bpback to top protein sequence of SMED30033622-orf-1 >SMED30033622-orf-1 ID=SMED30033622-orf-1|Name=SMED30033622-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1048bp MFKMFWQLFFLYTVVKSEFSVKLYLSVEENQKPNSPIGNLIKLIQNQTKSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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