Non-specific serine/threonine protein kinase

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPE                                PPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPE--------------------------------PPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 461          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  852 KLIKFTEHNMNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLD 1706
            ++++  E   N  + D    DKK +VY + +        + + + E+       K   P      P K+ F   D KF ++R+  +      L+D+      ++VR FF ++  + D                E+N++LG SE K A   DFD++ TIGKGSFG+V+  R K    ++A+K+L KE+I+K+NEVKH+M+ERN+L+ N +HPFL  L+FSFQ K KLYF LD++NGGELF HLQ+E+ FS+ R++FYAAEI  +LGYLH KNIIYRDLKPEN+LLD
Sbjct:   10 RMVRKDEVTCNVIIGD----DKKTVVYALRI---GNGPIMQKTFEEYERFFTTEKDMIPATIFTAPKKK-FLQADSKFYEKRRVWILVISQHLVDNN--LRSEDVRRFFHLESPDDD----------------ENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLD 268          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 2504
            G+++LTDFGLCKE ++   TTSTFCGTPEYLAPE+I K+PYD++VDWW  GSV+YEM+FGLPPFYS+D ++MY +I+N PL L+ N     S+++  L++K+  +RLG++NDF +I+ HPFF  +DW  L+N+++K PF+P+V +  D  NI  EF +  I  S    Q     QL+V   D  F  F++V
Sbjct:  271 GYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPSSLAPQ-----QLAVTHRDHDFENFTFV 456          

Query:  855 LIKFTEHNMNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLD 1706
            +++  E   N  + D    DKK +VY + +        + + + E+       K   P      P K+ F   D KF ++R+  +      L+D+      ++VR FF ++  + D                E+N++LG SE K A   DFD++ TIGKGSFG+V+  R K    ++A+K+L KE+I+K+NEVKH+M+ERN+L+ N +HPFL  L+FSFQ K KLYF LD++NGGELF HLQ+E+ FS+ R++FYAAEI  +LGYLH KNIIYRDLKPEN+LLD
Sbjct:    1 MVRKDEVTCNVIIGD----DKKTVVYALRI---GNGPIMQKTFEEYERFFTTEKDMIPATIFTAPKKK-FLQADSKFYEKRRVWILVISQHLVDNN--LRSEDVRRFFHLESPDDD----------------ENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLD 258          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 2504
            G+++LTDFGLCKE ++   TTSTFCGTPEYLAPE+I K+PYD++VDWW  GSV+YEM+FGLPPFYS+D ++MY +I+N PL L+ N     S+++  L++K+  +RLG++NDF +I+ HPFF  +DW  L+N+++K PF+P+V +  D  NI  EF +  I  S    Q     QL+V   D  F  F++V
Sbjct:  261 GYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPSSLAPQ-----QLAVTHRDHDFENFTFV 446          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFTPISRLMK*FRSRKVV-RKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPF---YSQDTHQ-----MYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDE----IKVHPFFSQ-IDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPI 2513
            DF  +  IG+GS+ KV  A   S   ++A+K++ KE   +  ++  + +E+++      +PFL  L+  FQT+ +L+F +++V GG+L FH+Q++R   ++ A+F                                       Y G++IL  +F+            SR ++ R LK                            LI   GHI LTD+G+CKE I+    TSTFCGTP Y+APE+++ + Y  SVDWW+ G +++EM+ G  PF     Q++ +     ++Q IL   + +  +     S IL   + K+P ERLG K D +E    +K H FF   IDW AL  K V PP+ P V S+ D+ + D +F  E    S  N  +  R   S       F GF YV P+
Sbjct:  252 DFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARF---------------------------------------YSGEIILALHFL-----------HSRGIIYRDLKLDNV------------------------LIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFDHQFTDELPQLSPDNPDVIARIDQS------EFDGFEYVNPL 589          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY---KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GH  L DFG+CKEGI ++  TSTFCGTP+Y+APE++++  Y  SVDWW+ G ++YEM+ G PPF + +   +++ ILN  +           +IL   + KN  +RLG    +   D I+ HPFF +IDW AL ++QVKPPF P++ S  D  N D +F KE    +  +  + R          D F GFS++ P
Sbjct:  427 GHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAIN------QDEFRGFSFINP 616          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ 1712
            DF F+K +GKGSFGKV LA RK    V+A+K+L K+ I + ++V+  M E+ IL    +HPFL  L+ SFQT  +L+F ++YVNGG+L F +Q+ R F + RA+FYAAE+  +L +LH  ++IYRDLK +NILLDA+
Sbjct:  290 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLDAE 426          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY---KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GH  L DFG+CKEGI ++  TSTFCGTP+Y+APE++++  Y  SVDWW+ G ++YEM+ G PPF + +   +++ ILN  +           +IL   + KN  +RLG    +   D I+ HPFF +IDW AL ++QVKPPF P++ S  D  N D +F KE    +  +  + R          D F GFS++ P
Sbjct:  514 GHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAIN------QDEFRGFSFINP 703          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ 1712
            DF F+K +GKGSFGKV LA RK    V+A+K+L K+ I + ++V+  M E+ IL    +HPFL  L+ SFQT  +L+F ++YVNGG+L F +Q+ R F + RA+FYAAE+  +L +LH  ++IYRDLK +NILLDA+
Sbjct:  377 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLDAE 513          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 2432
            GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  320 GHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487          

Query: 1089 KQRKEGLNEFVTKLLDSPDIWEL-KEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q  E +    ++L+D  ++     E  D   +D      +E   Q +V     +   +     EN       F+F+K +GKG+FGKV L R K+   ++A+K+L KE I +++EV H ++E  +L ++  HPFL  L +SFQT  +L F + YVNGGELF+HL  ER F++ R +FY AEI S+LGYLHS+ IIYRDLK EN+LLD    I V  +
Sbjct:  119 QQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLEN-------FEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL-KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADF 327          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 2432
            GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  320 GHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487          

Query: 1089 KQRKEGLNEFVTKLLDSPDIWEL-KEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q  E +    ++L+D  ++     E  D   +D      +E   Q +V     +   +     EN       F+F+K +GKG+FGKV L R K+   ++A+K+L KE I +++EV H ++E  +L ++  HPFL  L +SFQT  +L F + YVNGGELF+HL  ER F++ R +FY AEI S+LGYLHS+ IIYRDLK EN+LLD    I V  +
Sbjct:  119 QQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLEN-------FEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL-KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADF 327          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 2432
            GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  320 GHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487          

Query: 1089 KQRKEGLNEFVTKLLDSPDIWEL-KEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q  E +    ++L+D  ++     E  D   +D      +E   Q +V     +   +     EN       F+F+K +GKG+FGKV L R K+   ++A+K+L KE I +++EV H ++E  +L ++  HPFL  L +SFQT  +L F + YVNGGELF+HL  ER F++ R +FY AEI S+LGYLHS+ IIYRDLK EN+LLD    I V  +
Sbjct:  119 QQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLEN-------FEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL-KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADF 327          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 2432
            GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  320 GHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487          

Query: 1089 KQRKEGLNEFVTKLLDSPDIWEL-KEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q  E +    ++L+D  ++     E  D   +D      +E   Q +V     +   +     EN       F+F+K +GKG+FGKV L R K+   ++A+K+L KE I +++EV H ++E  +L ++  HPFL  L +SFQT  +L F + YVNGGELF+HL  ER F++ R +FY AEI S+LGYLHS+ IIYRDLK EN+LLD    I V  +
Sbjct:  119 QQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLEN-------FEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL-KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADF 327          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNS----PLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKE-PISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GH  L DFG+CKEGI     T+TFCGTP+Y+APE++K++ Y  SVDWW+ G ++YEM+ G PPF + +  +++  I++     P+ L     S++   L     KNP++RLG   D +EI+ HPFF+++DW  L  + +KPPF P++ +  D  N D EF KE P+   I N  +    Q       D F GFS+V P
Sbjct:  359 GHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLT----KNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQ-------DEFAGFSFVNP 545          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ 1712
            DF+FIK +GKGSFGKV LA +K    ++A+KVL K+ I + ++V   M+E+ IL     HPFL  L+  FQT  +L+F ++YVNGG+L F +QK R F   RA FYAAE+  +L +LH+  +IYRDLK +NILLD +
Sbjct:  222 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQE 358          

Query:  897 DQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDR-QNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q    K+Y VYK+ V      WFV RRY EF  L + LKK  P LNLK+P KR+FG  FDP+FIKQR+ GL+EF+ +++    +    +V+ F  +D+ +N+    + S++  D++     NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +A+KVL K+ I  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQKER+F + RA+FY AE+ S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   17 EQRDKKKRYTVYKVMVSVGRHEWFVFRRYAEFDKLYNTLKKQFPALNLKIPAKRIFGDNFDPEFIKQRRAGLHEFIQRIVSHSQLCSHPDVKVFLQMDKAKNF---SDGSEDEDDKSNSTSRNINLGPSANPHAKPTDFDFLKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKKVILNRREQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPEPRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDF 295          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDEN 2522
            GHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY  IL+  L +R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V S  DI N DPEF +E +  S+  S        SV + DD+F+GFSY PP +++
Sbjct:  288 GHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYDNILHKELVMRPGASTAAWSILQTLLEKDHTRRLGYRDDFNEVKEHEFFSSINWYDLEQKKLSPPFNPSVESQYDISNFDPEFTEETVPNSVCFSSGPSIVNASVMEADDAFLGFSYAPPSEDS 484          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQRK GLN+F+ KL  +    +  EV+    +       + E+   N          INLG S N  AKP+DFDF+K IGKGSFGKV LAR +SD   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   10 FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNL---TPPQDVELMNSNPSPPPSPSQQINLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 224          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQRK GLN+F+ KL  +    +  EV+    +       + E+   N          INLG S N  AKP+DFDF+K IGKGSFGKV LAR +SD   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   11 FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTP---PQDVELMNSNPSPPPSPSQQINLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 225          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDW 2072
            GHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDW
Sbjct:  218 GHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDW 264          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQRK GLN+F+ KL  +    +  EV+    +       + E+   N          INLG S N  AKP+DFDF+K IGKGSFGKV LAR +SD   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   29 FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTPP---QDVELMNSNPSPPPSPSQQINLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 243          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG+ +DF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+  SI  S  +     S+ +  ++F+GFSY P +D 
Sbjct:  236 GHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIGCSPDSALVTSSITEATEAFLGFSYAPAMDS 431          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQRK GLN+F+ KL  +    +  EV+    +       + E+   N          INLG S N  AKP+DFDF+K IGKGSFGKV LAR +SD   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   29 FMKQRKMGLNDFIQKLSANSYACKHPEVQSILNLTPP---QDVELMNSNPSPPPSPSQQINLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 243          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG+ +DF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+  SI  S  +     S+ +  ++F+GFSY P +D 
Sbjct:  236 GHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIGCSPDSALVTSSITEATEAFLGFSYAPAMDS 431          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHE-EEVSQENVDE-NYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP FI+QR+ GLNEF+  LL   ++    +V+ F  +D   +  +  E   E VD+ N     ++NLG S N  AKP+DF+++K IGKGSFGKV L R K DG  +AVKVL K  I  + E +HIM+ERN+L++N++HPFL  L++SFQT  KL+F LD++NGGELFFHLQ+ER F++ RA FYAAEIGS+LGYLHS +IIYRDLKPENILLD+Q  I++  +
Sbjct:   23 KRFTVYKVIVSMGRNEWFVFRRYAEFDKLYNTLRKQYPHMNLKIPAKRIFGDNFDPDFIQQRRAGLNEFIQNLLRHSELCSHSDVQSFLQLDSPKHQSDPSEDEDERVDQKNGSASRDVNLGPSGNPHAKPSDFEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHPFLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSIDIIYRDLKPENILLDSQGHIVLTDF 299          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPE 2018
            GHI+LTDFGLCKEGI    TT TFCGTPE
Sbjct:  292 GHIVLTDFGLCKEGISNSDTTLTFCGTPE 320          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHE-EEVSQENVDE-NYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP FI+QR+ GLNEF+  LL   ++    +V+ F  +D   +  +  E   E VD+ N     ++NLG S N  AKP+DF+++K IGKGSFGKV L R K DG  +AVKVL K  I  + E +HIM+ERN+L++N++HPFL  L++SFQT  KL+F LD++NGGELFFHLQ+ER F++ RA FYAAEIGS+LGYLHS +IIYRDLKPENILLD+Q  I++  +
Sbjct:   29 KRFTVYKVIVSMGRNEWFVFRRYAEFDKLYNTLRKQYPHMNLKIPAKRIFGDNFDPDFIQQRRAGLNEFIQNLLRHSELCSHSDVQSFLQLDSPKHQSDPSEDEDERVDQKNGSASRDVNLGPSGNPHAKPSDFEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHPFLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSIDIIYRDLKPENILLDSQGHIVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHI+LTDFGLCKEGI    TT TFCGTPEYLAPEVI K+PYD +VDWW  GSV+YEML GLPPFY++DT  MY+ IL+ PL  R +       IL +L+ K+PK RLG  NDF  IK H FF+ I+W  LV K++ PP+ P V+   DI N D EF +E +  S+  S        SVE+ DD+FVGFSY PP D+
Sbjct:  298 GHIVLTDFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNTVDWWCLGSVLYEMLHGLPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPKLRLGVNNDFVHIKNHAFFASINWADLVEKKMTPPYDPHVNGPDDISNFDKEFTEEMVPYSVCVSSDYSIVNASVEEADDAFVGFSYAPPSDD 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHE-EEVSQENVDE-NYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP FI+QR+ GLNEF+  LL   ++    +V+ F  +D   +  +  E   E VD+ N     ++NLG S N  AKP+DF+++K IGKGSFGKV L R K DG  +AVKVL K  I  + E +HIM+ERN+L++N++HPFL  L++SFQT  KL+F LD++NGGELFFHLQ+ER F++ RA FYAAEIGS+LGYLHS +IIYRDLKPENILLD+Q  I++  +
Sbjct:   29 KRFTVYKVIVSMGRNEWFVFRRYAEFDKLYNTLRKQYPHMNLKIPAKRIFGDNFDPDFIQQRRAGLNEFIQNLLRHSELCSHSDVQSFLQLDSPKHQSDPSEDEDERVDQKNGSASRDVNLGPSGNPHAKPSDFEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHPFLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSIDIIYRDLKPENILLDSQGHIVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHI+LTDFGLCKEGI    TT TFCGTPEYLAPEVI K+PYD +VDWW  GSV+YEML GLPPFY++DT  MY+ IL+ PL  R +       IL +L+ K+PK RLG  NDF +IK H FF+ I+W  LV K++ PP+ P V+   DI N D EF +E +  S+  S        SVE+ DD+FVGFSY PP D+
Sbjct:  298 GHIVLTDFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNTVDWWCLGSVLYEMLHGLPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPKLRLGVNNDFQDIKNHAFFASINWADLVEKKMTPPYDPHVNGPDDISNFDKEFTEEMVPYSVCVSSDYSIVNASVEEADDAFVGFSYAPPSDD 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP FI+QR+ GLNEF+  LL   ++    +V+ F  +D     H+ + S+   DE+   +  +N  +     AKP+DF+++K IGKGSFGKV L R K DG  +AVKVL K  I  + E +HIM+ERN+L++N++HPFL  L++SFQT  KL+F LD++NGGELFFHLQ+ER F++ RA FYAAEIGS+LGYLHS +IIYRDLKPENILLD+Q  I++  +
Sbjct:   23 KRFTVYKVIVSMGRNEWFVFRRYAEFDKLYNTLRKQYPHMNLKIPAKRIFGDNFDPDFIQQRRAGLNEFIQNLLRHSELCSHSDVQSFLQLDSPK--HQSDPSE---DEDERVDQKVNYSILNLCSAKPSDFEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHPFLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSIDIIYRDLKPENILLDSQGHIVLTDF 292          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHI+LTDFGLCKEGI    TT TFCGTPEYLAPEVI K+PYD +VDWW  GSV+YEML GLPPFY++DT  MY+ IL+ PL  R +       IL +L+ K+PK RLG  NDF +IK H FF+ I+W  LV K++ PP+ P V+   DI N D EF +E +  S+  S        SVE+ DD+FVGFSY PP D+
Sbjct:  285 GHIVLTDFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNTVDWWCLGSVLYEMLHGLPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPKLRLGVNNDFQDIKNHAFFASINWADLVEKKMTPPYDPHVNGPDDISNFDKEFTEEMVPYSVCVSSDYSIVNASVEEADDAFVGFSYAPPSDD 480          

Query:  927 VYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP FI+QR+ GLNEF+  LL                       H E  S  ++         +NL       AKP+DF+++K IGKGSFGKV L R K DG  +AVKVL K  I  + E +HIM+ERN+L++N++HPFL  L++SFQT  KL+F LD++NGGELFFHLQ+ER F++ RA FYAAEIGS+LGYLHS +IIYRDLKPENILLD+Q  I++  +
Sbjct:   12 VYKVIVSMGRNEWFVFRRYAEFDKLYNTLRKQYPHMNLKIPAKRIFGDNFDPDFIQQRRAGLNEFIQNLLR----------------------HSELCSHYSI---------LNLCS-----AKPSDFEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHPFLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSIDIIYRDLKPENILLDSQGHIVLTDF 246          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHI+LTDFGLCKEGI    TT TFCGTPEYLAPEVI K+PYD +VDWW  GSV+YEML GLPPFY++DT  MY+ IL+ PL  R +       IL +L+ K+PK RLG  NDF  IK H FF+ I+W  LV K++ PP+ P V+   DI N D EF +E +  S+  S        SVE+ DD+FVGFSY PP D+
Sbjct:  239 GHIVLTDFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNTVDWWCLGSVLYEMLHGLPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPKLRLGVNNDFVHIKNHAFFASINWADLVEKKMTPPYDPHVNGPDDISNFDKEFTEEMVPYSVCVSSDYSIVNASVEEADDAFVGFSYAPPSDD 434          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPE 2018
            GH++LTDFGLCKEGI    TT+TFCGTPE
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPE 326          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYL 2024
            GH++LTDFGLCKEGI    TT+TFCGTPE L
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEIL 328          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ KN + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ KN + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ KN + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP+DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTPKPHSTSRNINLGPTGNPHAKPSDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYDR+VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ KN + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ KN + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  +   D  E+  + +  + +    NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +
Sbjct:   29 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDF 305          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:  298 GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 493          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            GHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  234 GHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK-NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPMD 427          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQR+ GLN+F+ KL ++    +  EV+ +  I +     E E+   N          INLG S N  AKP+DF F+K IGKGSFGKV LAR K++ A +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L+FSFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   27 FMKQRRMGLNDFIQKLANNSYACKHPEVQSYLKISQ---PQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDF 241          

Query:  915 KKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID--RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY----PGDMILRFYFVFTPISRLMK*FRSRKVV--RKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            K++ VYK+ V      WFV RRY EF  L + LKK  P + LK+P KR+FG  FDP FIKQR+ GLNEF+  L+  P+++   +VR F  +D  R   D  E+  + +  + +    NINLG + N  AKP DFDF+K IGKGSFGKV LA+RK DG  +AVKVL K+ +  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD++NGGELFFHLQ+ERSF + RA+FYAAEI S+LGYLHS  I+YRDLKPENILLD+   +++  +     G  I      F     L    +  +     + +F  A     +  + S  + +R       L+   GH++LTDFGLCKEGI    TT+TFCGTPEYLAPEVI+K+PYD +VDWW  G+V+YEML+GLPPFY +D  +MY  IL+ PL LR         IL +L+ K+ + RLG K DF EI+ HPFF  + W  LV K++ PPF P V+   DIRN D  F +E +  S+  S        SV + DD+FVGFSY PP ++
Sbjct:   23 KRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTQKLHSTSQNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFINGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDTVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSED 566          

Query:  885 ARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGK-RLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGID----------RQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ 1712
            A++ + ET  KK  VYKI V     SWF+LRRY EF+ L D LKK  P   LKLP K R FG  D ++++QR+E L+  V  L+  P I EL +V +F G+D               H   V           E+NI+LG  EN+ A P+DF F+K IGKGSFGKVFLA+RKSDG +FAVKVL KE IKKRNEVKHIMSERN+LV+N+ HPFLC L+ SF+T  KLYF LDYVNGGELFFHLQ+ERSFS+ RA+FYAAEI S++GYLHSK+IIYRDLKPENILLD++
Sbjct:    6 AQIVESETT-KKATVYKICVSSGGNSWFILRRYKEFSNLYDRLKKQYPEAGLKLPSKPRFFGGADAEYLRQRREALHSMVQILMTHPQISELPDVINFLGLDVNPSRLTSASTSTATHASAVEGAADTGGGKEEENIDLGAKENRKATPSDFAFLKVIGKGSFGKVFLAKRKSDGRIFAVKVLQKEQIKKRNEVKHIMSERNVLVRNIEHPFLCALHMSFRTPDKLYFVLDYVNGGELFFHLQRERSFSESRARFYAAEIASAIGYLHSKSIIYRDLKPENILLDSE 291          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GH+ LTDFGLCKEG+  + TTSTFCGTPEYLAPEV++KEPYD +VDWW  GSV+YEMLFGLPPFYS++  +MY  IL+ PL L+ +  S   D+L KL++K+ + RLG   D  E++ HPFF+ IDW  L  ++++PPF P++ S      ID EF +EP+  S+  S    +   SV++ D+ F+GFSYVPP
Sbjct:  292 GHVRLTDFGLCKEGLNTKSTTSTFCGTPEYLAPEVLRKEPYDMAVDWWCLGSVLYEMLFGLPPFYSREKSEMYSNILHKPLQLKPSASSASQDVLNKLLQKSRQNRLGSNGDIQEVRKHPFFATIDWQLLEQRKIEPPFKPKLMSPLSTEYIDSEFTREPVPQSVGRSI---KISASVQEADNDFMGFSYVPP 481          

Query:  876 NMNARVADQET--IDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGT-FDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDA 1709
            ++ A V   ET  ++KK+ VYK+ V    + WFV RRY+EF  L D LKK   NL LKLPGK+LFG   DP+F+ QR+EGLN FV +L+  P +  ++EVR F  +D  +    EE S E+  E    ++N+NLG SE   AKP DF+F+  IGKGSFGKV LAR + D   +AVKVL K  I ++NE +HIMSERN+L++NL HPFL  L+FSFQT+ KL+F LDYVNGGELFFHLQ+ER+F++ RA+FYAAEI S+LGYLHS+ IIYRDLKPEN+LLD+
Sbjct:   14 DIEASVQKTETWQLNKKFTVYKVVVVSPTECWFVFRRYNEFYKLHDILKKQVSNLQLKLPGKKLFGNNLDPQFVAQRREGLNAFVQQLMQDPKLLNIEEVRTFLQLD-GHCQTTEEPSTEDTCEKAEEDENLNLGPSERTYAKPGDFEFLHVIGKGSFGKVLLARHRHDNVYYAVKVLSKRLIVRQNEAQHIMSERNVLMKNLHHPFLVGLHFSFQTRDKLFFVLDYVNGGELFFHLQRERTFTEPRARFYAAEIASALGYLHSQGIIYRDLKPENLLLDS 293          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQR 2156
            GH++LTDFGL KEG+    TT+TFCGTPEYLAPEV++KE YDRSVDWW  G+V+YEML+GLPPFYS++T +MY +
Sbjct:  295 GHVVLTDFGLSKEGLLATDTTNTFCGTPEYLAPEVVRKEAYDRSVDWWCLGAVLYEMLYGLPPFYSRNTAEMYAQ 369          

Query: 1041 KLPGKRLFGT-FDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFTPISRLMK*FRSRKVVRKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            K P  +LF +  +P F+KQ++ GLN+ + KL  S   +  K   +   +   +    E           P    INLG S N  AKP+DF+ +K IGKGSFGKV LA+ K+D   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L            +  +    +L+F                       L Y++   + Y  L+ E   L+ +              RFY     I+  +    S K+V    +R  + E I                   L+   GHI+LTDFGLCKE IE  GTT TFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   D+L  L++K+  +RLG K DF +IK H FFS I+WV L  K++ PPF P VS  AD+++ DPEF +EP+  SI  S  N     SV+   D+F+GFSY PP+D
Sbjct:  173 KHPSAKLFTSNCNPAFMKQKRMGLNDLIQKLAASQS-YACKHSSEVPAMLHISPTETEMNGTGASPPPSPTTAQINLGPSSNPQAKPSDFNLLKVIGKGSFGKVLLAKHKADDQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGL------------YYSFQTADKLYF----------------------VLDYINGGELFYH-LQRERCFLEPRA-------------RFYAA--EIASALGYLHSLKIV----YRDLKPENI-------------------LLDRQGHIVLTDFGLCKENIEPNGTTCTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLLLKPNISNSARDLLEGLLQKDRTKRLGAKEDFMDIKAHIFFSSINWVDLNAKKLTPPFNPNVSGPADLQHFDPEFTEEPVPNSIGRSPDNALITASVKAASDAFLGFSYAPPMD 591          

Query:  867 TEHNMNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNY------DHEEEVSQENVDE---------------NYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYR 1676
             E    A++ + ++  KK  VYKI V    +SWF+LRRY EF  L D LKK  P   LKLPGKR FG  DP+FI+QR+EGL+  V  L+  P I EL EV  F G D          D +++ +    DE                   E+ ++LG  EN+ A P+DF F+K IGKGSFGKVFLA+RKSDG +FAVKVL KE IKKRNEVKHIMSERN+LV+N+ HPFLC L+ SF+T  KLYF LDYVNGGELFFHLQ++R F + RA+FYAAEI S++GYLHSKNIIYR
Sbjct:    5 AEKESAAQIVEADST-KKATVYKICVTSGGQSWFILRRYKEFNNLYDRLKKQFPEAGLKLPGKRFFGNMDPEFIRQRQEGLDNMVQVLMTHPKISELPEVIQFLGFDINKSRLELTDDAKKDTASSGSDEPPIAAAAAAEGGTGSGAKEEEALDLGAKENRKATPSDFTFLKVIGKGSFGKVFLAKRKSDGGIFAVKVLQKEQIKKRNEVKHIMSERNVLVRNIEHPFLCALHMSFRTPDKLYFVLDYVNGGELFFHLQRDRCFPEPRARFYAAEIASAIGYLHSKNIIYR 294          

Query:  897 DQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q    K+Y VYK+ V      WFV RRY EF  L + LKK  P LNLK+P KR+FG  FDP+FIKQR+ GL+EF+ K++  P +    +VRDF  +++  Y  +   + E+ +EN P   NINLG S N  AKP DFDF+K IGKGSFGKV LA+RK DG  +A+KVL K+ I  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQKER+F + RA+FY AE+ S+LGYLHS NI+YRDLKPENILLD Q  I++  +
Sbjct:   17 EQRDKKKRYTVYKVMVSVGRHEWFVFRRYTEFDKLYNTLKKQYPALNLKIPAKRIFGDNFDPEFIKQRRTGLHEFIQKIVSHPQLSNHPDVRDFLQMNKSKYFSD---ASEDEEENSPTSGNINLGPSANPHAKPTDFDFLKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKKVILNRREQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPESRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDFQGHIVLTDF 294          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDEN 2522
            L+ F GHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY+ IL+  LP+R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V S  DI N DPEF +E +  S+  S  +     SV + DD+F+GFSY PP D++
Sbjct:  282 LLDFQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYENILHKELPMRPGASTTAWSILQGLLEKDNTRRLGYRDDFNEVKSHDFFSSINWDDLEQKKIPPPFNPSVDSQYDISNFDPEFTEETVPNSVCISTEHSIVNASVMEADDAFLGFSYAPPSDDS 483          

Query: 1032 LNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNY------DHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            LNLK+P KR+FG  FDP+FIKQR+ GL+EF+ K++  P +    +VRDF  +++  Y      D EE+V +              +G+     AKP DFDF+K IGKGSFGKV LA+RK DG  +A+KVL K+ I  R E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQKER+F + RA+FY AE+ S+LGYLHS NI+YRDLKPENILLD Q  I++  +
Sbjct:    1 LNLKIPAKRIFGDNFDPEFIKQRRTGLHEFIQKIVSHPQLSNHPDVRDFLQMNKSKYFSDASEDEEEKVCK-------------IIGLILVNSAKPTDFDFLKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKKVILNRREQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPESRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDFQGHIVLTDF 229          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDEN 2522
            L+ F GHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY+ IL+  LP+R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V    DI N DPEF +E +  S+  S  +     SV + DD+F+GFSY PP D++
Sbjct:  217 LLDFQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYENILHKELPMRPGASTTAWSILQGLLEKDNTRRLGYRDDFNEVKSHDFFSSINWDDLEQKKIPPPFNPSV---YDISNFDPEFTEETVPNSVCISTEHSIVNASVMEADDAFLGFSYAPPSDDS 415          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            GHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  213 GHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 406          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            FIK+RK GLN+F+ KL+ SP I +  +V  F  ID    +  EE+ +E      P        ++E    KP DFD++K IGKGSFGKV LAR K     +AVKVL K+ I K+ E KHIM+ER++L++N++HPFL  L++SFQT  KLYF LDYVNGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS +I+YRDLKPENILLD+Q  I++  +
Sbjct:   11 FIKERKMGLNDFIQKLVSSPHICQHSQVGSFLKIDE---NQNEELGREQFCLTNPRSS-----LAEETQIKPCDFDYLKIIGKGSFGKVLLARHKETEQYYAVKVLQKKIILKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERVFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDF 220          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            GHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  229 GHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 422          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            FIK+RK GLN+F+ KL+ SP I +  +V  F  ID    +  EE+ +E      P        ++E    KP DFD++K IGKGSFGKV LAR K     +AVKVL K+ I K+ E KHIM+ER++L++N++HPFL  L++SFQT  KLYF LDYVNGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS +I+YRDLKPENILLD+Q  I++  +
Sbjct:   27 FIKERKMGLNDFIQKLVSSPHICQHSQVGSFLKIDE---NQNEELGREQFCLTNPRSS-----LAEETQIKPCDFDYLKIIGKGSFGKVLLARHKETEQYYAVKVLQKKIILKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERVFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDF 236          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            GHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  205 GHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 398          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            FIK+RK GLN+F+ KL      ++L     +  +  +                                 KP DFD++K IGKGSFGKV LAR K     +AVKVL K+ I K+ E KHIM+ER++L++N++HPFL  L++SFQT  KLYF LDYVNGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS +I+YRDLKPENILLD+Q  I++  +
Sbjct:   27 FIKERKMGLNDFIQKLYIYVISFQLAYRLYYICLSNR--------------------------------IKPCDFDYLKIIGKGSFGKVLLARHKETEQYYAVKVLQKKIILKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERVFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDF 212          

Query: 1011 LKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHE-DNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            LKK  P LN+KLP K +FG T D  FIKQR+ GLN F+ +++  P + +  +V+ F  +D +     +  +Q N + N  ++ D INLG S N  AK  DFDF+K IGKGSFGKV LA+ K+DG  +AVKVL K  I KR E KHIM+ERN+L++N++HPFL  L+FSFQT  KLYF LDYVNGGELF HLQ+ER FS++RA+FYAAEI S++G+LHS NI+YRDLKPENILLD++  I++  +
Sbjct:    1 LKKQFPELNVKLPSKSIFGNTLDGVFIKQRRNGLNSFIQRVVSDPHVCQHPDVQAFLQMDHRGKKRSQPAAQTNSNHNLNNDSDTINLGPSANPQAKTTDFDFLKVIGKGSFGKVLLAKHKTDGKFYAVKVLQKSAILKRREQKHIMAERNVLLKNVKHPFLVGLHFSFQTADKLYFILDYVNGGELFLHLQRERCFSEQRARFYAAEIASAIGHLHSLNIVYRDLKPENILLDSKGHIVLTDF 244          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPE 2018
            GHI+LTDFGLCKEGIE + TTSTFCGTPE
Sbjct:  237 GHIVLTDFGLCKEGIEPKDTTSTFCGTPE 265          

Query: 1056 RLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            R   T    F+K RK GLN+F  K++ +P + +  +VR F  +D  N  ++ +   EN        D+INLG S N  AKP+DFDF+  +GKGSFGKV LA+ KSDG  +AVKV+ K  I ++ E KHIM+ERN+LV+N+RHPFL  L++SFQ+  KLYF +DYVNGGELFFHLQ++ SF + RAQFYAAEIGS++GYLHS NI+YRDLKPENILLD Q  I++  +
Sbjct:   17 RAVATVLVAFLKHRKTGLNDFTQKVVSNPGMCQNPDVRKFLQLD--NPRNQTQGPMEN------DADHINLGPSANLQAKPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDF 235          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            L+ + GHI+LTDFGLCKEGI+   TT TFCGTPEYLAPEV+KK PYDR+VDWW  G V+YEML+GLPPFYS++  QMY+ IL+ PL LR    +    +L  L+ K+P +RLG  +D  EIK H FFS I+W  L  K++  P+ P VS   D+ N DP F  EP+S S+  S        +V++  D+FVGF+Y+P +++
Sbjct:  223 LLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSDILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMSMAQSSDTSSVCANVDEAADAFVGFTYMPGLED 423          

Query: 1299 ADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ 1712
            ADF F+K +GKGSFGKV LA  +    VFAVKVL K++I + ++V+  M+E+ +L     HP+L +L+  FQT+ +L+F ++YVNGG+L F +Q+ R F + R++FYAAE+ S+L +LH   +IYRDLK +NILLDA+
Sbjct:    4 ADFSFMKVLGKGSFGKVMLAELRGSEEVFAVKVLKKDSIVQDDDVECTMTEKRVLALAKNHPYLTQLFCCFQTRDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHRHGVIYRDLKLDNILLDAE 141          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 2432
            GHI + DFGLCKEGI    T  TFCGTPEYLAPEV++   Y R+VDWW  G V+YEM+ G  PFY+QD  ++++ IL   +       +    +L  L++K+PK+RLG   +D  EI  H FF+ I W  + ++++ PPF PQV+S  D R  D EF  + I+ + P+
Sbjct:  286 GHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDEEFTAQTITITPPD 453          

Query: 1251 EDNINLGVSENKLAKPA------DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHS-KNIIYRDLKPENILLDAQVSIMVKTY 1736
            ED  +    +  L+KP       +FD++K +GKG+FGKV L R K+ G  +A+K+L KE I  ++EV H ++E  +L Q  +HPFL  L +SFQT  +L F ++YVNGGELFFHL +ER FS+ R +FY AEI S+L YLH+ KN++YRDLK EN++LD    I +  +
Sbjct:  126 EDGSSTEQMDTILSKPKSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVL-QTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADF 293          

Query: 1290 AKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            AKP DFDF+K IGKGSFGKV LA+ K+D   +AVKVL K+ I K+ E KHIM+ERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGE+             + + Y  E    L  LH  N I RDLKPENILLD +  I++  +
Sbjct:    4 AKPTDFDFLKIIGKGSFGKVLLAKLKTDEKFYAVKVLQKKAILKKKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYINGGEVRTSTCAPCIVVHHKWKGYREEPIDELNSLHFVNQISRDLKPENILLDFEGHIILTDF 152          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPE---YLAPEVIKKEPYDRSVDW-----WSFGSV------IYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            L+ F GHIILTDFGLCKEGI+   TTSTFCGTPE       + I+ +   R+  W     W  G V      + E+ F   P +SQ + +    I NS             D+L  L+ K+  +RLG   DF EIK H FFS I+W  L++K++ PPF P V+  +D+R+ DPEF  EP+ GS+  S        S ++  D+F GFSY PP
Sbjct:  140 LLDFEGHIILTDFGLCKEGIQPNDTTSTFCGTPEESDLTNRKEIRSQRSSRTRGWDLRCAWRAGQVTTHRPSVSEVSFV--PSFSQ-SRRFKPNISNS-----------ARDLLEGLLHKDRTQRLGASGDFTEIKGHVFFSPINWEDLLSKKIVPPFNPNVNGPSDLRHFDPEFISEPVPGSVCRSPGEFAVSASFQEARDAFAGFSYAPP 337          

Query: 1287 LAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQ--KERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFTPISRLMK*FRSRKVVRKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPL--PLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNA 2372
            +  P  F+ I+ +G+G  GKVFL R K    V+A+KVL K+ + KRN++K +++E+ IL  +  HPF+  LY SFQ++  LY  ++Y  GGE F  LQ  K +   +  A+FYA+E+ ++L YLH    IYRDLKPENILL     IM+  +  D+ ++                            A+D  +  +  S                      L D  +C +G      T++F GT EY+APEVI+   +  +VDWW+ G +IYEMLFG  PF   +T++ +  IL + +  P          D++ KL+ KN  +RLG K    ++K HPFF ++ W  L N++  PP +P +S + 
Sbjct:  490 MVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATS-NHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDF--DLSIQ----------------------------AKDSKVPVVKGS------------------AQSTLVDTKICSDGFR----TNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQE--PPLIPVLSEDG 800          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 2504
            L+ + GHI L DFGLCK  ++ +  T TFCGTPEYLAPE++    Y ++VDWW+ G ++YEML GLPP+Y +D  +MY++IL  PL           D+L+ L+ ++P  RLGY N  DEI+ HPFFSQ+ W  L+ K   PP+ P VS++ D  N D EF +E    S+ +  L+       E V   F G++YV
Sbjct:  477 LLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGY-NGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLS-------ESVQKQFGGWTYV 664          

Query: 1275 SENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMV 1727
            S NK     DFD +K IGKGSFGKV   R+K    V+A+K + K  I  ++EV H ++ER +L + +  PF+  L FSFQ+  KLYF L ++NGGELF+HLQKE  F   RA+FY AE+  +L  LH  +++YRDLKPENILLD Q  I +
Sbjct:  337 SRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLAR-VDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIAL 486          

Query: 1917 LITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 2531
            L+ + GHI L DFGLCK  ++    T TFCGTPEYLAPE++  + Y ++VDWW+ G ++YEM+ GLPP+Y ++   MY++IL  PL           D+L+ L+ ++P  RLG  N  DEI+ HPFF  I W  L+ K   PP+ P V S  D  N D EF KE    S+ +  L+   Q         F G++Y+   DE + +
Sbjct:  474 LLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGV-NGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQ-------KQFGGWTYIG--DEQLGD 668          

Query: 1275 SENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMV 1727
            S+NK     DFD +K IGKGSFGKV   R+K    ++A+K L K  I  + EV H ++ER +L + +  PF+  L FSFQ+  KLY  L ++NGGELF+HLQ E  FS  R++FY AE+  +L  LH  ++IYRDLKPENILLD Q  I +
Sbjct:  334 SKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLAR-VDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIAL 483          

Query: 1296 PADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLR--HPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMV 1727
            P DF+ ++ +GKG+FG+V+  ++K    ++A+KVL K+ I K+NE+ H + ERNILV       PF+  L FSFQT   LY   DY++GGELF+HLQKE  FS+ RA+FY AE+  +L +LH  +I+YRDLKPENILLDA  +I +
Sbjct:  409 PQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIAL 554          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEP-YDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVK-LIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV--PPIDENMAN 2531
            G+I L DFGL K  ++    T+TFCGT EYLAPE++  E  Y + VD+WS G +I+EM  G  PF++++  +MYQ+I    +    +  S      VK L+ +NPK RLG  +D  E++ HPFF+ IDW AL  K++ PPF P + S  D  N DPEF     S    +  +   T LS   +   F GF++V    IDE++ N
Sbjct:  550 GNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPA-MQAKFAGFTFVDESAIDEHVNN 750          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLD 1706
            DF  ++T+G GSFG+V L R   +G  +A+KVL K+ + K  +V+H   ER +L + + HPFL R++ +FQ  R ++  +DY+ GGELF  L+K + F    A+FYAAE+  +L YLH+ NIIYRDLKPENILLD
Sbjct:   69 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRML-KLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLD 202          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSN 2369
            GHI +TDFG  KE    +  T T CGTP+Y+APEVI  +PY++SVDWWS G +IYEML G  PFY     + Y++IL   +         + D+L KLI  +   R+G  ++   +IK HP+FS++ W  L+ K ++ P+ P ++S 
Sbjct:  205 GHIKITDFGFAKE---VQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSG 348          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDR----QNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
             IK R+EGLN+F+ K+L  P   +  +VR+F  +D     Q  D +E+   ++ D      + I+LG S N  AKP+DF F+K IGKGSFGKVFL++ K +   +A+KVL K  I+KRNE KHIM+ERN+LVQN+ HPFL  L++SFQTK KLYF LDYVNGGELFFHLQ+ER F + RA+FYAAEI S++GYLH   IIYRDLKPENILLD++  I++  +
Sbjct:    1 MIKMRREGLNDFIVKILTHPGALDHPDVREFLSLDNPKNAQANDEDEQPGSDDADV-----EKIDLGESNNPKAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDF 217          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY-KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 2525
            GHI+LTDFGLCKEGI+R GTTSTFCGTPEYLAPEV++K+ YD+SVDWW  G+V+YEM++GLPPFYS+DT +MY  IL+ PL LR N       IL  L++K+  +RLG  + DF++I+ H FF  I+W  LV + ++PP+ P VS   D+++ DPEF +EP+ GS+  S  +     SV+D DD+FVGF+YV P D+ +
Sbjct:  210 GHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPVPGSVGKSADSNFVSASVDDPDDAFVGFTYVAPSDDTL 408          

Query: 1296 PADFDFIKTIGKGSFGKVFLARRK---SDGAVFAVKVLYKENI-KKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFTPISRLMK*FRSRKVVRKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            P  F+ +K +GKG +GKVFL ++    S   +FA+KVL K  I + + +  H  +ERNIL + ++HPF+  L ++FQT            GG+L+  L+                      YL S   ++  L+ E I L+                   F  + IS  ++    + +V    +R  + E I                   L+   GH+ LTDFGLCKE I     T TFCGT EY+APE++ +  + ++VDWWS G+++Y+ML G PPF + +  +   +IL   L +         D + KL++++P+ RL G   D + IK H FF  I W  L+ K+V+PPF P +S   D+   D +F ++    S  +S L+       E   + F GF+YV P
Sbjct:   62 PESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNIL-ECVKHPFIVDLIYAFQT------------GGKLYLILE----------------------YL-SGGELFMQLEREGIFLEDTAC---------------FYLSEISMALEHLHKQGIV----YRDLKPENI-------------------LLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFDSKFTRQTPVDSPDDSMLS-------ESASNIFQGFTYVAP 390          

Query: 1302 DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDA 1709
            DF FIK +GKGSFGKV LA RK    V+A+K+L KE++ + ++V+  M ER +L  +  HPFL  L+ SFQT  +L+F ++YVNGG+L F +QK R F + R++FYAAE+  +L +LH   +IYRDLK +N+LLDA
Sbjct:  382 DFTFIKVLGKGSFGKVLLAERKGTDEVYAIKILKKESVLQDDDVECTMIERRVLALSAGHPFLTSLHSSFQTVERLFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFLHQNGVIYRDLKLDNVLLDA 517          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNS----PLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDE--IKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDD-SFVGFSYVPP 2510
            GHI L DFG+CKE +    TT+TFCGTP+Y+APE+++++PY  SVDWW+ G ++YEM+ G PPF +++   +++ IL+     P+ L     S    IL   + KN  +RLG      E  I+ H FF  I++  L  +Q+ PPF P++ S  D+ N D +F KE         +L    +  + ++D   F GFS+V P
Sbjct:  519 GHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQPPFEAENEEDLFESILHDDVLYPVWLSREAVS----ILKGFMTKNYLKRLGCTPTSTESSIREHAFFRLINFEKLEARQINPPFKPKIRSRTDVGNFDTDFTKE-------EPKLTPTDRNVIVNIDQREFRGFSFVNP 707          

Query: 1293 KPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +P DF F+K +GKGSFGKV LA RK    V+A+KVL K+ I + ++V+  M+E+ +L    + PFL +L+  F +  +LYF +++VNGG+L FH+Q+   F + +A FYAAEI   L +LH + I+YRDLK +N++LD+   I +  +
Sbjct:  212 RPEDFHFLKVLGKGSFGKVMLAERKGTDQVYAIKVLKKDVIVQDDDVECTMTEKRVLAVPGKPPFLTQLFCCFHSVDRLYFVMEFVNGGDLMFHIQQAGRFKEPQAVFYAAEIVIGLVFLHKRGIVYRDLKLDNVMLDSDGHIKIADF 359          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFG 2111
            GHI + DFG+CKE +    TT TFCGTP+Y+APE++  +PY  SVDWW+ G +IYEML G
Sbjct:  352 GHIKIADFGMCKESMFNNQTTRTFCGTPDYIAPEIVAYQPYGFSVDWWALGVLIYEMLAG 411          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFY--------SQDTHQ-MYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY--KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDS-FVGFSYVPPI 2513
            GHI LTD+G+CKEGI     TSTFCGTP Y+APE+++ E Y  SVDWW+ G ++YEML G  PF          Q+T   ++Q IL  P+ +  +     + IL   + KNP ERLG   +  F +I  H FF  + W  L  +QV PPF P+      + N DP+F  E +  +  + ++       +E +D + F GF Y+ P+
Sbjct:  358 GHIKLTDYGMCKEGIRPGDVTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIVGSADNPDQNTEDYLFQVILEKPIRIPRSLSVKAASILKGYLNKNPTERLGCHPQTGFADITSHAFFRTVSWEQLEARQVTPPFKPRQEDPYGLENFDPQFTNEDVQFTPDDPKM-------LETIDQTEFEGFEYINPL 556          

Query: 1269 GVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY--------PGDMILRF 1760
            G     L    DF+ I+ IG+GS+ KV L   K    ++A+KV+ KE +    ++  + +E+++  Q   HPFL  L+  FQT  +L+F ++YV+GG+L +H+Q++R   +  A+FY+AEI  +L +LH K +IYRDLK +N+LLD+   I +  Y        PGD+   F
Sbjct:  210 GSGAGALISVNDFNLIRVIGRGSYAKVMLVELKKTKRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTSSRLFFVIEYVSGGDLMYHMQRQRRLPEDHARFYSAEICCALNFLHEKGVIYRDLKLDNVLLDSDGHIKLTDYGMCKEGIRPGDVTSTF 381          

Query:  897 DQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFG-TFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            +Q    K+Y VYK+ V      WFV RRY EF  L + L+K  P++NLK+P KR+FG  FDP+FI+QR+ GL+EF+ +L+  P +    +V+ F  +D++   H  + S++  D+N     +INLG S N  AKP DFDF+K IGKGSFGKVFLA+RK DG  +A+KVL K+ I  R E KHIM+ERN+LV+N++HPFL  L++SFQT  KLYF LD+VNGGELFFHLQKER+F + RA+FY AE+ S+LGYLHS  I+YRDLKPENILLD +  I++  +
Sbjct:   23 EQRDKKKRYTVYKVLVSVGQHEWFVFRRYAEFDKLYNTLRKQFPSMNLKIPAKRIFGDNFDPEFIQQRRAGLHEFIKRLVSHPQLCNHPDVKSFLQMDKRQ--HLADASEDEDDKNSSTSRDINLGPSGNPQAKPTDFDFLKVIGKGSFGKVFLAKRKHDGKFYAIKVLQKKVILNRKEQKHIMAERNVLVKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPEPRARFYIAEMASALGYLHSLKIVYRDLKPENILLDHEGHIVLTDF 301          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDEN 2522
            GHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV+KK PYD +VDWW  GSV+YEMLFGLPPFYS+DTH+MY  IL+ PL +R    S    +L  L+ K+  +RLG   DF+EIKVH FFS I+W  LV K++ PPF+P V+S  DI N DPEF +E +  SI  +Q +     SV + DD+F+GFSY PP D++
Sbjct:  294 GHIVLTDFGLCKEGISQTDTTTTFCGTPEYLAPEVLKKHPYDNTVDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLAMRPGASSTAWSLLQGLLEKDGTQRLGSNGDFNEIKVHNFFSSINWDDLVQKKIPPPFIPNVTSCCDISNFDPEFTEENVPNSICWTQSHSVVNASVMEADDAFLGFSYAPPSDDS 490          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 2519
            GHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +RLG  NDF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+S SI  S  +     S+++  ++FVGFSY P +D 
Sbjct:  234 GHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNSARNLLEGLLQKDRTKRLGCTNDFIEIKNHVFFSPINWDELNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVSSSIGCSPDSALFTASIKEAAEAFVGFSYAPSMDS 429          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            F+KQR+ GLN+F+ +L  +    +  EV+    +       + E+   N          INLG S N  AKP+DF F+K IGKGSFGKV LAR ++D   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:   27 FMKQRRMGLNDFIQRLATNSYACKHPEVQSILNLSPP---QDAELMNVNPSPPSSPSQQINLGPSSNPSAKPSDFHFLKVIGKGSFGKVLLARHRTDDQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 241          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 2516
            GHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +RLG  NDF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+S SI  S  +     S+++  ++FVGFSY P +D
Sbjct:  357 GHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNSARNLLEGLLQKDRTKRLGCTNDFIEIKNHVFFSPINWDELNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVSSSIGCSPDSALFTASIKEAAEAFVGFSYAPSMD 551          

Query: 1074 DPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            D  F+KQR+ GLN+F+ +L  +    +  EV+    +       + E+   N          INLG S N  AKP+DF F+K IGKGSFGKV LAR ++D   +AVKVL K+ I K+ E KHIMSERN+L++N++HPFL  L++SFQT  KLYF LDY+NGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS NI+YRDLKPENILLD+Q  I++  +
Sbjct:  147 DNTFMKQRRMGLNDFIQRLATNSYACKHPEVQSILNLSPP---QDAELMNVNPSPPSSPSQQINLGPSSNPSAKPSDFHFLKVIGKGSFGKVLLARHRTDDQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDF 364          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GHI+LTDFGLCKEG+E +GTTSTFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+    ++ N  +   ++L  L++K   +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P VS   D+R+ DPEF + P+S S+ N  L   +  SV++   +F GFSY PP
Sbjct:  231 GHIVLTDFGLCKEGLEADGTTSTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKAPAMKPNVSNAGRELLEGLLQKERTKRLGAKDDFLELKYHSFFSPINWDDLMAKKITPPFIPSVSGPTDLRHFDPEFTQLPVSSSLCNDTLTVTS--SVKEAAGAFPGFSYGPP 421          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINL----GVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            FIK+RK GLN+F  KL+ +P I +  EV +F  ID +N + E+E        +   E  + L     ++E    KP+DFD++K IGKGSFGKV LAR K   A +AVKVL K+ I K+ E KHIM+ER++L++N++HPFL  L++SFQT  KLYF LDYVNGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS +I+YRDLKPENILLD+Q  I++  +
Sbjct:   25 FIKERKMGLNDFFQKLVSTPHICQHAEVNNFLKID-ENQNEEDE-------NDLLSESRMCLKSRSSLAEETQIKPSDFDYLKIIGKGSFGKVLLARHKETMAYYAVKVLQKKIILKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERVFLEPRARFYAAEISSALGYLHSLHIVYRDLKPENILLDSQGHIVLTDF 238          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 2510
            GHI+LTDFGLCKEG+E +GTTSTFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+    ++ N  +   ++L  L++K   +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P VS   D+R+ DPEF + P+S S+ N  L   +  SV++   +F GFSY PP
Sbjct:  217 GHIVLTDFGLCKEGLEADGTTSTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKAPAMKPNVSNAGRELLEGLLQKERTKRLGAKDDFLELKYHSFFSPINWDDLMAKKITPPFIPSVSGPTDLRHFDPEFTQLPVSSSLCNDTLTVTS--SVKEAAGAFPGFSYGPP 407          

Query: 1083 FIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINL----GVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            FIK+RK GLN+F  KL+ +P I +  EV +F  ID +N + E+E        +   E  + L     ++E    KP+DFD++K IGKGSFGKV LAR K   A +AVKVL K+ I K+ E KHIM+ER++L++N++HPFL  L++SFQT  KLYF LDYVNGGELF+HLQ+ER F + RA+FYAAEI S+LGYLHS +I+YRDLKPENILLD+Q  I++  +
Sbjct:   11 FIKERKMGLNDFFQKLVSTPHICQHAEVNNFLKID-ENQNEEDE-------NDLLSESRMCLKSRSSLAEETQIKPSDFDYLKIIGKGSFGKVLLARHKETMAYYAVKVLQKKIILKKKEQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERVFLEPRARFYAAEISSALGYLHSLHIVYRDLKPENILLDSQGHIVLTDF 224          

Query:  879 MNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTY 1736
            MNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQ  I++  +
Sbjct:    1 MNARVADQETIDKKYIVYKIAVDHDNKSWFVLRRYHEFTCLMDFLKKSAPNLNLKLPGKRLFGTFDPKFIKQRKEGLNEFVTKLLDSPDIWELKEVRDFFGIDRQNYDHEEEVSQENVDENYPHEDNINLGVSENKLAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQGHIILTDF 286          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 2531
            GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN
Sbjct:  279 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 478          

Query: 1287 LAKPADFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFTPISRLMK*FRSRKVVRKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIP 2429
            L    +F+ IKT+G GSFG V L + K      ++KVL K+ + +  ++ H +SE+ IL   + HPF+ +L +SF+    LY  ++YV+GGE+F HL+    + +    F+             K I  R           Q+ +  K      +   YF    I      F + +VV   ++    +           +A+R       LI   G+I +TDFG  K   +R   T T CGTPEYLAPE++  + Y  ++DWW+ G +IYEM  G PPFY  D  ++Y++IL     ++ +    +  I+  L+ K+   RLG  K+   ++K H +F   +W+ + NK+   P++P +   +D RN D     E  S  IP
Sbjct:   38 LCSINNFERIKTLGTGSFGMVLLVKDKKTSEYLSIKVLSKKRVHRMKQIDHTISEKKIL-SCVEHPFIVKLLYSFKDNYNLYMVMEYVSGGEMFSHLRNSIKYEKFPPTFF------------HKLIFKRKF---------QLDVFRKFTKSSEMEVIYFGIGQIVEKQTRFYAGQVVLAFEYLHYLN-----------IAYRDLKPENILIDRTGYIKITDFGFAKRIQKR---TYTLCGTPEYLAPEILLNKGYSMAIDWWALGVLIYEMTCGYPPFYDTDPLKIYEKILKGKYKIQKSFSETLFSIISGLLEKDLTHRLGNLKDGSKDLKNHKWFESFEWIRVFNKREPAPYIPLILDESDARNFDDFEETEIGSCDIP 383          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQL 2459
            GHI LTDFGLCKE +     T TFCGTPEYLAPEV+    Y RSVDWW  G V+YEM+ G  PFY+ D   +++ IL   + L  +      D+L +L+ KNP ER+G    D  EI +HPFF  IDW  L+ K++ PP+VP V  + D + I  EF +EP++ + P +  N  +Q+
Sbjct:  376 GHIKLTDFGLCKEEMYYGAFTKTFCGTPEYLAPEVLLDNDYSRSVDWWGLGVVMYEMMCGRLPFYNVDHEILFELILQENIKLPVHLTLSGQDMLSRLLIKNPNERIGGGVQDAVEIMIHPFFDNIDWDLLIKKKINPPWVPDVVDDKDTKYIPDEFAREPVTLTPPKNNNNYLSQI 552          

Query: 1254 DNINLGVSENKLAKPA--DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFT 1775
            +N++L VS   + +    DF  +  +GKG+FGKV L + K  G  +A+K+L K  + +++EV+H  +E  +L Q  RHPF+ +L +SF T   L F ++YVNGGE+++HL K R FS++R +FYAAEI  ++GYLHS+N+IYRDLK EN+LLD +  I +  +       +Y  FT
Sbjct:  222 ENVDLEVSRRPIKRYGLQDFQLLALLGKGTFGKVILCKEKETGTFYAMKILKKAVLIEKDEVEHTRTESRVL-QQFRHPFMTQLKYSFTTTDYLCFVMEYVNGGEIYYHLSKARIFSEERTKFYAAEILLAIGYLHSQNVIYRDLKLENLLLDCEGHIKLTDFGLCKEEMYYGAFT 396          

Query: 1932 GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQL 2459
            GHI LTDFGLCKE +     T TFCGTPEYLAPEV+    Y RSVDWW  G V+YEM+ G  PFY+ D   +++ IL   + L  +      D+L +L+ KNP ER+G    D  EI +HPFF  IDW  L+ K++ PP+VP V  + D + I  EF +EP++ + P +  N  +Q+
Sbjct:  377 GHIKLTDFGLCKEEMYYGAFTKTFCGTPEYLAPEVLLDNDYSRSVDWWGLGVVMYEMMCGRLPFYNVDHEILFELILQENIKLPVHLTLSGQDMLSRLLIKNPNERIGGGVQDAVEIMIHPFFDNIDWDLLIKKKINPPWVPDVVDDKDTKYIPDEFAREPVTLTPPKNNNNYLSQI 553          

Query: 1254 DNINLGVSENKLAKPA--DFDFIKTIGKGSFGKVFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENILLDAQVSIMVKTYPGDMILRFYFVFT 1775
            +N++L VS   + +    DF  +  +GKG+FGKV L + K  G  +A+K+L K  + +++EV+H  +E  +L Q  RHPF+ +L +SF T   L F ++YVNGGE+++HL K R FS++R +FYAAEI  ++GYLHS+N+IYRDLK EN+LLD +  I +  +       +Y  FT
Sbjct:  223 ENVDLEVSRRPIKRYGLQDFQLLALLGKGTFGKVILCKEKETGTFYAMKILKKAVLIEKDEVEHTRTESRVL-QQFRHPFMTQLKYSFTTTDYLCFVMEYVNGGEIYYHLSKARIFSEERTKFYAAEILLAIGYLHSQNVIYRDLKLENLLLDCEGHIKLTDFGLCKEEMYYGAFT 397          

Query: 1347 VFLARRKSDGAVFAVKVLYKENIKKRNEVKHIMSERNILVQNLRHPFLCRLYFSFQTKRKLYFFLDYVNGGELFFHLQKERSFSQKRAQFYAAEIGSSLGYLHSKNIIYRDLKPENIL--LDAQVSIMVKTYPGDMILRF-YFVFTPISRLMK*FRSRKVVRKLKFR*ARDECIIFIIIS*LVAFRASL*YAHLITF*GHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIP 2429
            V L + K      ++KVL K+ + +  ++ H +SE+ IL   + HPF+ +L +SF+    LY  ++YV+GGE+F HL+    + +    F+   I      L       +  + E I   +   V    + Y G ++L F Y  +  I+                +R  + E I                   LI   G+I +TDFG  K   +R   T T CGTPEYLAPE++  + Y  ++DWW+ G +IYEM  G PPFY  D  ++Y++IL     ++ +    +  I+  L+ K+   RLG  K+   ++K H +F   +W+ + NK+   P++P +   +D RN D     E  S  IP
Sbjct:    2 VLLVKDKKTSEYLSIKVLSKKRVHRMKQIDHTISEKKIL-SCVEHPFIVKLLYSFKDNYNLYMVMEYVSGGEMFSHLRNSIKYEKFPPTFFHKLIFKRKFQLDVFRKFTKSSEMEVIYFGIGQIVEKQTRFYAGQVVLAFEYLHYLNIA----------------YRDLKPENI-------------------LIDRTGYIKITDFGFAKRIQKR---TYTLCGTPEYLAPEILLNKGYSMAIDWWALGVLIYEMTCGYPPFYDTDPLKIYEKILKGKYKIQKSFSETLFSIISGLLEKDLTHRLGNLKDGSKDLKNHKWFESFEWIRVFNKREPAPYIPLILDESDARNFDDFEETEIGSCDIP 327