SMED30033541

Overview
NameSMED30033541
Smed IDSMED30033541
Length (bp)1631
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30033541 (SMED30033541) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30033541 (SMED30033541) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30033541 (SMED30033541) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30033541 (SMED30033541) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033541

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30033541SMESG000061837.1 SmedASXL_014607SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30033541SMESG000061837.1 dd_Smed_v4_14985_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30033541SMESG000061837.1 dd_Smed_v4_14985_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30033541SMESG000061837.1 dd_Smed_v6_14985_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30033541SMESG000061837.1 dd_Smed_v4_14985_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30033541 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.000195:33275..45622 -8012
Homology
BLAST of SMED30033541 vs. Ensembl Human
Match: LRRC63 (leucine rich repeat containing 63 [Source:HGNC Symbol;Acc:HGNC:34296])

HSP 1 Score: 104.76 bits (260), Expect = 3.359e-23
Identity = 65/184 (35.33%), Postives = 93/184 (50.54%), Query Frame = 2
Query:  866 GGSIKQEIEDPYQEITP-TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWR 1411
            G   K      Y+ IT  T ++++ C + GR  LNL    I   P+   +   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F LIT +P GLFS   LE+ D+SYN +  IP+ +    +L+ L + GN + +F      L L  I  EN + HP FWR
Sbjct:  294 GEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWR 477          
BLAST of SMED30033541 vs. Ensembl Human
Match: LRRC63 (leucine rich repeat containing 63 [Source:HGNC Symbol;Acc:HGNC:34296])

HSP 1 Score: 104.76 bits (260), Expect = 4.124e-23
Identity = 65/184 (35.33%), Postives = 93/184 (50.54%), Query Frame = 2
Query:  866 GGSIKQEIEDPYQEITP-TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWR 1411
            G   K      Y+ IT  T ++++ C + GR  LNL    I   P+   +   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F LIT +P GLFS   LE+ D+SYN +  IP+ +    +L+ L + GN + +F      L L  I  EN + HP FWR
Sbjct:  294 GEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWR 477          
BLAST of SMED30033541 vs. Ensembl Human
Match: LRRC63 (leucine rich repeat containing 63 [Source:HGNC Symbol;Acc:HGNC:34296])

HSP 1 Score: 104.76 bits (260), Expect = 4.124e-23
Identity = 65/184 (35.33%), Postives = 93/184 (50.54%), Query Frame = 2
Query:  866 GGSIKQEIEDPYQEITP-TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWR 1411
            G   K      Y+ IT  T ++++ C + GR  LNL    I   P+   +   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F LIT +P GLFS   LE+ D+SYN +  IP+ +    +L+ L + GN + +F      L L  I  EN + HP FWR
Sbjct:  294 GEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWR 477          
BLAST of SMED30033541 vs. Ensembl Human
Match: LRRC8D (leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992])

HSP 1 Score: 66.6254 bits (161), Expect = 8.295e-11
Identity = 54/165 (32.73%), Postives = 85/165 (51.52%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHL--LESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYF-KKSFTNLKLESIGLENTWIHPLFWRKGEFS 1426
            M     L L +  +  IP+ +    NL+ LDL  N  + I E I   HL  L  L L +N +  I  SIT++ +L+S   S   + S+P  +FS + L   D+SYNNI+ IP  + +  NL+ L+++GN +    K+ F  +KL ++ L    I  L  + G+ S
Sbjct:  634 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLS 798          
BLAST of SMED30033541 vs. Ensembl Human
Match: LRRC8D (leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992])

HSP 1 Score: 66.6254 bits (161), Expect = 8.295e-11
Identity = 54/165 (32.73%), Postives = 85/165 (51.52%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHL--LESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYF-KKSFTNLKLESIGLENTWIHPLFWRKGEFS 1426
            M     L L +  +  IP+ +    NL+ LDL  N  + I E I   HL  L  L L +N +  I  SIT++ +L+S   S   + S+P  +FS + L   D+SYNNI+ IP  + +  NL+ L+++GN +    K+ F  +KL ++ L    I  L  + G+ S
Sbjct:  634 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLS 798          
BLAST of SMED30033541 vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972924:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413)

HSP 1 Score: 66.6254 bits (161), Expect = 2.358e-11
Identity = 65/230 (28.26%), Postives = 100/230 (43.48%), Query Frame = 2
Query:  956 THLNLSSHS-----------------------ISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIHPLFWRKGEF-SLDEFEYSWAF-CDLCDQIISDRSINYISFTKKFNHILPILMSFCSTL 1564
            T LNLSS+                        ++ +P+ +    NLR+L+   N  + IP  I +L  LE L+L  N L+ +   I  L SL+ F      +TS+P  +  C+ L+Q D+S N I  +P ++    NL  LN+S N I     SF  LK L+ +  +   +H L    G+  SL E      F  DL D I   R +  ++        +P  +  C +L
Sbjct:  108 TTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSL 337          

HSP 2 Score: 52.7582 bits (125), Expect = 5.374e-7
Identity = 49/185 (26.49%), Postives = 86/185 (46.49%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNL-KLESIGLENTWIHPLFWRKGEF-SLDEFEY----------SWAFCDLCDQI 1477
            LNL+ ++I  + + +   ++LRILD+S N   ++P +I  L  L  LNL  N +  + D++ N   L +   S    T +P  +  C ++    L+  ++  +P ++   +NL++L    N +R    S   L KLE + L    +  L    G+  SL EF            S + C + DQ+
Sbjct:   41 LNLTMNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQL 225          

HSP 3 Score: 50.8322 bits (120), Expect = 2.251e-6
Identity = 32/110 (29.09%), Postives = 59/110 (53.64%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            +T    LNL+ +SI+ +P+ ++  + L  L+LS N F  +PE I +   +  L+L    L ++  +I +L +L+       L+ +IP  +   + LE+ DL  N + A+P
Sbjct:   81 LTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALP 190          
BLAST of SMED30033541 vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972934:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413)

HSP 1 Score: 66.6254 bits (161), Expect = 2.378e-11
Identity = 65/230 (28.26%), Postives = 100/230 (43.48%), Query Frame = 2
Query:  956 THLNLSSHS-----------------------ISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIHPLFWRKGEF-SLDEFEYSWAF-CDLCDQIISDRSINYISFTKKFNHILPILMSFCSTL 1564
            T LNLSS+                        ++ +P+ +    NLR+L+   N  + IP  I +L  LE L+L  N L+ +   I  L SL+ F      +TS+P  +  C+ L+Q D+S N I  +P ++    NL  LN+S N I     SF  LK L+ +  +   +H L    G+  SL E      F  DL D I   R +  ++        +P  +  C +L
Sbjct:  108 TTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSL 337          

HSP 2 Score: 52.7582 bits (125), Expect = 5.579e-7
Identity = 49/185 (26.49%), Postives = 86/185 (46.49%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNL-KLESIGLENTWIHPLFWRKGEF-SLDEFEY----------SWAFCDLCDQI 1477
            LNL+ ++I  + + +   ++LRILD+S N   ++P +I  L  L  LNL  N +  + D++ N   L +   S    T +P  +  C ++    L+  ++  +P ++   +NL++L    N +R    S   L KLE + L    +  L    G+  SL EF            S + C + DQ+
Sbjct:   41 LNLTMNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQL 225          
BLAST of SMED30033541 vs. Ensembl Celegans
Match: fli-1 (pep chromosome:WBcel235:III:8675297:8683732:-1 gene:WBGene00001443.1 transcript:B0523.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:fli-1)

HSP 1 Score: 66.6254 bits (161), Expect = 3.710e-11
Identity = 53/132 (40.15%), Postives = 71/132 (53.79%), Query Frame = 2
Query:  950 GRTHLNLSSHSISAIPNFVEV-FQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIID----DSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPI 1327
            G   LNLS ++I  IPN V     +L  LDLS N+  ++P QI +L +L+SL L+NNPL         S+T+L+ L     + TL  +IP  L    NL   D S NN+  +P       NL+ LNLSGN I
Sbjct:  127 GSIVLNLSYNNIETIPNSVCANLIDLLFLDLSNNKLDMLPPQIRRLSMLQSLKLSNNPLNHFQLKQLPSMTSLSVLHMSNTNRTL-DNIPPTLDDMHNLRDVDFSENNLPIVPEALFKLRNLRKLNLSGNKI 257          
BLAST of SMED30033541 vs. Ensembl Celegans
Match: ZK546.2 (pep chromosome:WBcel235:II:4947036:4948070:1 gene:WBGene00022759.1 transcript:ZK546.2b.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK546.2)

HSP 1 Score: 61.6178 bits (148), Expect = 2.080e-10
Identity = 44/149 (29.53%), Postives = 73/149 (48.99%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQN-LRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHS-NLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPL 1402
            L L    +  +P+ +E   + LR L+LS N+ + IP  I Q   L+ L+LANN L+ + D + ++  L+    +   + ++P  +  C +L+  DLS N     P   +    L ILNL+GN I       +NLK+  + L    +  L
Sbjct:   42 LQLKGTGLKKVPDEIEPLADVLRNLELSENKIREIPIFIGQFSQLKQLHLANNCLEFLPDELGSMKKLEILNLAGNKLKALPDTIVGCTDLKTIDLSSNVFTVFPVAVIGCLQLDILNLNGNQIESLPDDISNLKVIELSLNQNRLSSL 190          
BLAST of SMED30033541 vs. Ensembl Celegans
Match: ZK546.2 (pep chromosome:WBcel235:II:4946573:4948070:1 gene:WBGene00022759.1 transcript:ZK546.2b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK546.2)

HSP 1 Score: 61.6178 bits (148), Expect = 2.080e-10
Identity = 44/149 (29.53%), Postives = 73/149 (48.99%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQN-LRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHS-NLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPL 1402
            L L    +  +P+ +E   + LR L+LS N+ + IP  I Q   L+ L+LANN L+ + D + ++  L+    +   + ++P  +  C +L+  DLS N     P   +    L ILNL+GN I       +NLK+  + L    +  L
Sbjct:   42 LQLKGTGLKKVPDEIEPLADVLRNLELSENKIREIPIFIGQFSQLKQLHLANNCLEFLPDELGSMKKLEILNLAGNKLKALPDTIVGCTDLKTIDLSSNVFTVFPVAVIGCLQLDILNLNGNQIESLPDDISNLKVIELSLNQNRLSSL 190          
BLAST of SMED30033541 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308632)

HSP 1 Score: 61.6178 bits (148), Expect = 1.607e-9
Identity = 43/179 (24.02%), Postives = 83/179 (46.37%), Query Frame = 2
Query:  941 VMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSG-----------------------LFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            ++T  T+L++S + +  +PN +    +L  LDL+ N  + +P+ I +L  L  L L  N LQ ++D++ N  +++  I +   ++ +P+                        +  C NL    L  N +  + P +   + L +L++SGN + Y   S  NL+L+++ L      PL 
Sbjct:  219 LLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSENQSQPLL 397          

HSP 2 Score: 51.6026 bits (122), Expect = 1.732e-6
Identity = 35/123 (28.46%), Postives = 61/123 (49.59%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPI 1327
            L LS + I  +P  ++ F+NL  LD+S N    IP+ I  L  L+  + ++NP+  +    + L +L     +   +T++P+   S   LE  +L  N +  +P  +   + LK L+L  N I
Sbjct:   65 LGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEI 187          
BLAST of SMED30033541 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308623)

HSP 1 Score: 61.6178 bits (148), Expect = 1.632e-9
Identity = 43/179 (24.02%), Postives = 83/179 (46.37%), Query Frame = 2
Query:  941 VMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSG-----------------------LFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            ++T  T+L++S + +  +PN +    +L  LDL+ N  + +P+ I +L  L  L L  N LQ ++D++ N  +++  I +   ++ +P+                        +  C NL    L  N +  + P +   + L +L++SGN + Y   S  NL+L+++ L      PL 
Sbjct:  219 LLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSENQSQPLL 397          

HSP 2 Score: 51.6026 bits (122), Expect = 1.790e-6
Identity = 35/123 (28.46%), Postives = 61/123 (49.59%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPI 1327
            L LS + I  +P  ++ F+NL  LD+S N    IP+ I  L  L+  + ++NP+  +    + L +L     +   +T++P+   S   LE  +L  N +  +P  +   + LK L+L  N I
Sbjct:   65 LGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEI 187          
BLAST of SMED30033541 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0335522)

HSP 1 Score: 61.2326 bits (147), Expect = 1.833e-9
Identity = 43/179 (24.02%), Postives = 83/179 (46.37%), Query Frame = 2
Query:  941 VMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSG-----------------------LFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            ++T  T+L++S + +  +PN +    +L  LDL+ N  + +P+ I +L  L  L L  N LQ ++D++ N  +++  I +   ++ +P+                        +  C NL    L  N +  + P +   + L +L++SGN + Y   S  NL+L+++ L      PL 
Sbjct:  219 LLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSENQSQPLL 397          

HSP 2 Score: 51.6026 bits (122), Expect = 1.860e-6
Identity = 35/123 (28.46%), Postives = 61/123 (49.59%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPI 1327
            L LS + I  +P  ++ F+NL  LD+S N    IP+ I  L  L+  + ++NP+  +    + L +L     +   +T++P+   S   LE  +L  N +  +P  +   + LK L+L  N I
Sbjct:   65 LGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEI 187          
BLAST of SMED30033541 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308620)

HSP 1 Score: 61.2326 bits (147), Expect = 1.863e-9
Identity = 43/179 (24.02%), Postives = 83/179 (46.37%), Query Frame = 2
Query:  941 VMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSG-----------------------LFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            ++T  T+L++S + +  +PN +    +L  LDL+ N  + +P+ I +L  L  L L  N LQ ++D++ N  +++  I +   ++ +P+                        +  C NL    L  N +  + P +   + L +L++SGN + Y   S  NL+L+++ L      PL 
Sbjct:  219 LLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSENQSQPLL 397          

HSP 2 Score: 51.6026 bits (122), Expect = 1.859e-6
Identity = 35/123 (28.46%), Postives = 61/123 (49.59%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPI 1327
            L LS + I  +P  ++ F+NL  LD+S N    IP+ I  L  L+  + ++NP+  +    + L +L     +   +T++P+   S   LE  +L  N +  +P  +   + LK L+L  N I
Sbjct:   65 LGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEI 187          
BLAST of SMED30033541 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308621)

HSP 1 Score: 61.2326 bits (147), Expect = 1.863e-9
Identity = 43/179 (24.02%), Postives = 83/179 (46.37%), Query Frame = 2
Query:  941 VMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSG-----------------------LFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            ++T  T+L++S + +  +PN +    +L  LDL+ N  + +P+ I +L  L  L L  N LQ ++D++ N  +++  I +   ++ +P+                        +  C NL    L  N +  + P +   + L +L++SGN + Y   S  NL+L+++ L      PL 
Sbjct:  219 LLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSENQSQPLL 397          

HSP 2 Score: 51.6026 bits (122), Expect = 1.859e-6
Identity = 35/123 (28.46%), Postives = 61/123 (49.59%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPI 1327
            L LS + I  +P  ++ F+NL  LD+S N    IP+ I  L  L+  + ++NP+  +    + L +L     +   +T++P+   S   LE  +L  N +  +P  +   + LK L+L  N I
Sbjct:   65 LGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEI 187          
BLAST of SMED30033541 vs. Ensembl Zebrafish
Match: CABZ01080587.1 (leucine-rich repeat-containing protein 30-like [Source:NCBI gene;Acc:100534875])

HSP 1 Score: 63.929 bits (154), Expect = 9.641e-11
Identity = 40/122 (32.79%), Postives = 71/122 (58.20%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPI 1327
            L+L+++ I+A+PN +   + L  L+LS+NR + IP  +Y +  L+ L+LANN L+ + D I  L SLK  I    L+  +P  L     LE  ++ +N + ++P  D+H   ++  L+ +P+
Sbjct:  154 LSLANNQINALPNSLCSLRKLTKLNLSHNRIQHIPACVYSMRGLQFLHLANNRLENLADKIQELQSLKILILEQNLLQVLPRTLCCLTALELLNVDHNELQSLPE-DMHRLRRLQKLACHPL 274          
BLAST of SMED30033541 vs. Ensembl Zebrafish
Match: lrrc57 (leucine rich repeat containing 57 [Source:NCBI gene;Acc:436900])

HSP 1 Score: 61.6178 bits (148), Expect = 3.477e-10
Identity = 36/104 (34.62%), Postives = 57/104 (54.81%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            ++LS++ I  +P F+  FQ+L+   +S N+   +P  I +L  LE+L L  N L+ +  SI  L SL++   S       PSGL + + L+  DLS N I  +P
Sbjct:   43 VDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVP 146          
BLAST of SMED30033541 vs. Ensembl Zebrafish
Match: lrrc57 (leucine rich repeat containing 57 [Source:NCBI gene;Acc:436900])

HSP 1 Score: 61.2326 bits (147), Expect = 3.769e-10
Identity = 36/104 (34.62%), Postives = 57/104 (54.81%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            ++LS++ I  +P F+  FQ+L+   +S N+   +P  I +L  LE+L L  N L+ +  SI  L SL++   S       PSGL + + L+  DLS N I  +P
Sbjct:   43 VDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVP 146          
BLAST of SMED30033541 vs. Ensembl Zebrafish
Match: lrrc1 (leucine rich repeat containing 1 [Source:ZFIN;Acc:ZDB-GENE-050320-1])

HSP 1 Score: 62.003 bits (149), Expect = 8.933e-10
Identity = 46/151 (30.46%), Postives = 70/151 (46.36%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            T L +S + I  +P  +   + L IL    NR   +PE I     L  L L  N L  +  SI  L  L +F C    +TS+P  +  C +L    +  N +  I P +   S L +L+LSGN + Y   + T+L+L+++ L      PL 
Sbjct:  158 TDLLVSQNLIDLLPEGIGKLKRLSILKADQNRLVQLPESIGHCESLTELVLTENQLVNLPRSIGKLKKLSNFNCDRNRLTSLPKEIGGCCSLNVLCVRENRLMRIPPELSQASELHVLDLSGNRLLYLPLTLTSLRLKALWLSENQSQPLL 308          
BLAST of SMED30033541 vs. Ensembl Zebrafish
Match: lrrc18a (leucine rich repeat containing 18a [Source:ZFIN;Acc:ZDB-GENE-090313-323])

HSP 1 Score: 59.6918 bits (143), Expect = 1.553e-9
Identity = 62/229 (27.07%), Postives = 96/229 (41.92%), Query Frame = 2
Query:  821 KISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRT--HLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPL--QIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVD-VHSNLKILNLSGNPIRYFK---------KSFTNLKLESIGLENTWIHPLFWRKGEFSLDEFEYSWAFCDL 1465
            KI+  + K+ + A+  G ++ ++ +      P      +C++  R    L+LS + +  IP F+  F  LR LDL  N+ + +PE I  L  L  LNL NN L    +   I +L +L+        + ++P  L    NL +  L  N    +P    V  NL  LN   NP+ Y +         K+  NL L     E    HP   R  +  LD  +    F  L
Sbjct:   14 KITLKMAKNALRATPEGKLRLDLSNVGIATFP------KCLLKLRNVEELDLSRNKLKTIPEFIGQFTGLRWLDLHSNQIERLPENIGLLRSLVHLNLCNNNLDSAGLSPEIGSLRNLQVLNLGMNRLNALPPTLAGLTNLTELGLFDNLFTQVPECTRVLPNLTKLNTKRNPVVYRQRDGQDSDSMKTTGNLYLAR---EGDLCHPCLERCRKKKLDSLQKKSNFSGL 233          
BLAST of SMED30033541 vs. Ensembl Xenopus
Match: ENSXETT00000041368.1 (leucine rich repeat containing 63 [Source:NCBI gene;Acc:101734566])

HSP 1 Score: 100.523 bits (249), Expect = 5.455e-22
Identity = 72/251 (28.69%), Postives = 122/251 (48.61%), Query Frame = 2
Query:  908 ITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSN-LKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRK----GEFSLDEFEYSW------------------------AFCDLCDQIISDRSINYISFTKKFNHI--LPILMSFCSTLC 1567
            ++ +  +++E ++ G + LNL +  IS +P+   ++  L  L+LS+N  +  P+++Y+L  LE L L NNPL+ I   I +L  L+SFI SF L++S+P GLF    L+  D+SYN+I++I     +   L+ LN+ GN +         L+L  + + N  +HPLFWR+    G   L +   ++                          CD C   +    + +I   +K   +  LP +   CS  C
Sbjct:  229 VSRSNFAVLESLVHGGSILNLKAFFISKLPDLTPLYNTLVYLNLSFNDLRHFPKEVYKLEHLEVLKLRNNPLKEIPFGIHSLKKLRSFIMSFCLLSSLPEGLFQLSCLQVLDVSYNSISSISSNISNLRVLEFLNVEGNNLPALPCGALKLQLRCLRVRNNAMHPLFWRENSHIGPQRLTDLAAAFLARSNLFHQLNHIPSEGKQILENSRVCDCCRGSLYGEGLLFIRPCEKIFGVRKLPFMFRACSPTC 479          
BLAST of SMED30033541 vs. Ensembl Xenopus
Match: ENSXETT00000053046.1 (uncharacterized loc100170560 [Source:NCBI gene;Acc:100170560])

HSP 1 Score: 66.2402 bits (160), Expect = 8.077e-11
Identity = 43/123 (34.96%), Postives = 69/123 (56.10%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPI 1327
            L L  +SI+ IP+ +    NL  L +S+N    +P  ++    L  L L+NN ++ I   I NL++LK F  S+  I +IP  L+ C+ LE  +L +NNIN + P++   + L  L++  NPI
Sbjct:  634 LKLWHNSITKIPDHISKLANLEQLYISHNNIGDLPHDLFLCCKLRHLELSNNNIRSIPHIIRNLSNLKYFSVSYNRIETIPDELYFCQKLETLNLRHNNINTLSPNIGNLAQLSCLDVKENPI 756          

HSP 2 Score: 60.077 bits (144), Expect = 7.303e-9
Identity = 35/97 (36.08%), Postives = 56/97 (57.73%), Query Frame = 2
Query:  959 HLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLS 1249
            HL LS+++I +IP+ +    NL+   +SYNR + IP+++Y    LE+LNL +N +  +  +I NL  L         I S+P  L SC+ L++  LS
Sbjct:  679 HLELSNNNIRSIPHIIRNLSNLKYFSVSYNRIETIPDELYFCQKLETLNLRHNNINTLSPNIGNLAQLSCLDVKENPIGSLPLELGSCQALKRNGLS 775          

HSP 3 Score: 52.373 bits (124), Expect = 1.915e-6
Identity = 54/162 (33.33%), Postives = 75/162 (46.30%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPE--QIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIR------YFKKSFTNLKLESIGLENTWIHPL 1402
            M     L L +  +  IPN +     L+ LDL  N  K I E      L  L  L L +N +  I D I+ L +L+    S   I  +P  LF C  L   +LS NNI +IPH+  + SNLK  ++S N I       YF +     KLE++ L +  I+ L
Sbjct:  580 MANLMTLELVNCKLDQIPNSIFSLLALKELDLKNNNLKSIQEIASFQNLQKLSILKLWHNSITKIPDHISKLANLEQLYISHNNIGDLPHDLFLCCKLRHLELSNNNIRSIPHIIRNLSNLKYFSVSYNRIETIPDELYFCQ-----KLETLNLRHNNINTL 736          
BLAST of SMED30033541 vs. Ensembl Xenopus
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:100486200])

HSP 1 Score: 65.0846 bits (157), Expect = 1.011e-10
Identity = 47/148 (31.76%), Postives = 85/148 (57.43%), Query Frame = 2
Query:  947 TGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTL-ITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNL-KLESIGLE 1381
            T    L++++  I  IP+++++FQ L +LDLS+N+ + +P +I  L  L+  N++ N LQII   + N  +L+    S  L +T +P  L S K +   D+S N  ++IP  V   S+L+ L++S N ++   +    L +LE++ L+
Sbjct:  117 THLKQLHVNNTRIQTIPDYIQLFQKLIVLDLSHNKIRCLPPEIGYLANLKEFNISFNNLQIIPPELGNCENLEKLDLSGNLELTELPFELSSLKKVTFVDVSANKFSSIPICVLRMSSLQWLDISSNKLQDLPQDIDRLEELETLMLQ 264          

HSP 2 Score: 51.9878 bits (123), Expect = 1.705e-6
Identity = 41/139 (29.50%), Postives = 67/139 (48.20%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESI 1372
            T +++S++  S+IP  V    +L+ LD+S N+ + +P+ I +L  LE+L L  N +  +   ITNL  LK  + S   +  IPS L    +L+   L  N I     +D     +    S     YF+K F    +E +
Sbjct:  213 TFVDVSANKFSSIPICVLRMSSLQWLDISSNKLQDLPQDIDRLEELETLMLQKNKITYLSAEITNLTKLKLLVVSGESLVEIPSALEENPSLKYIKLLDNPIETNVCLDAKEERE----STQDQEYFEKEFMKAYIEDL 347          
BLAST of SMED30033541 vs. Ensembl Xenopus
Match: irx3 (iroquois homeobox 3 [Source:Xenbase;Acc:XB-GENE-480486])

HSP 1 Score: 61.6178 bits (148), Expect = 4.774e-10
Identity = 45/124 (36.29%), Postives = 70/124 (56.45%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKI--LNLSGNPI 1327
            ++LSS+ I A+P  V  F  L+ L L+ NR   +P+++ +L  LE+L+L+ N +  I      L +LK+   S   + ++P+ L   +NL+  DLS N I AIP  D  S L+   LNL+ N I
Sbjct:   43 IDLSSNKIEALPPMVGKFNLLKSLTLNNNRISRLPDELCRLKKLETLHLSGNQISQIPADFVQLLALKTLNLSGNQLRTLPAQLCKLRNLDVVDLSKNRIQAIP--DEVSGLQAIELNLNQNQI 164          

HSP 2 Score: 51.6026 bits (122), Expect = 9.127e-7
Identity = 38/144 (26.39%), Postives = 70/144 (48.61%), Query Frame = 2
Query:  968 LSSHSISAIP-NFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWI 1393
            L+   ++  P +   +  NLR +DLS N+ + +P  + + +LL+SL L NN +  + D +  L  L++   S   I+ IP+       L+  +LS N +  +P  +    NL +++LS N I+      + L+   + L    I
Sbjct:   21 LTGKGLTEFPEDLQRLSGNLRTIDLSSNKIEALPPMVGKFNLLKSLTLNNNRISRLPDELCRLKKLETLHLSGNQISQIPADFVQLLALKTLNLSGNQLRTLPAQLCKLRNLDVVDLSKNRIQAIPDEVSGLQAIELNLNQNQI 164          
BLAST of SMED30033541 vs. Ensembl Xenopus
Match: pparg (peroxisome proliferator activated receptor gamma [Source:Xenbase;Acc:XB-GENE-483136])

HSP 1 Score: 62.7734 bits (151), Expect = 8.642e-10
Identity = 47/154 (30.52%), Postives = 81/154 (52.60%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPL 1402
            +T    LN+S + I  +P  ++  QNL+ L L +N+ + +P+ I  L +LE L+++NN L+ I  S+  L  L  F  S   +T++P+ +   KNL+Q D + N +  +P  V    +L+ L L  N + Y  +     KL+ + + N  I  L
Sbjct:  127 LTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQNKLTYLPELPFLTKLKELHVGNNQIQTL 280          

HSP 2 Score: 51.9878 bits (123), Expect = 2.275e-6
Identity = 38/134 (28.36%), Postives = 73/134 (54.48%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            L++  + I ++P  ++   NL+ L++S+N+ K +P+++  L  L+SL L +N L+ + DSI +L+ L+    S   + SI S +     L + +LS N + A+P  +    NLK L+ + N +     S   ++
Sbjct:  110 LDIHDNQIVSLPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTEIGKMKNLKQLDCTSNLLENVPASVAGME 243          
BLAST of SMED30033541 vs. Ensembl Mouse
Match: Lrrc63 (leucine rich repeat containing 63 [Source:MGI Symbol;Acc:MGI:1918109])

HSP 1 Score: 87.4261 bits (215), Expect = 1.103e-17
Identity = 57/165 (34.55%), Postives = 84/165 (50.91%), Query Frame = 2
Query:  917 TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFW 1408
            T ++++ C + GR  LNL    ++  P+   V   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F  IT +P GLF    LE+ D+SYN I  I + +    +L+ L + GNPI  F      L L  + +ENT+    FW
Sbjct:  357 TTLAIINCQIYGRNALNLKGFFLANCPDLTPVAFQLVYLNLSFNDLNQFPIEILYLQNLQVLKLRNNPIKEIPSEIHLLTYLRIFSIAFNYITKLPDGLFCLNYLEELDVSYNEIENISNEIQKLRSLEKLIVDGNPITSFPPGILKLNLIKLQIENTFTCSQFW 521          
BLAST of SMED30033541 vs. Ensembl Mouse
Match: Lrrc69 (leucine rich repeat containing 69 [Source:MGI Symbol;Acc:MGI:1920564])

HSP 1 Score: 66.6254 bits (161), Expect = 1.921e-11
Identity = 50/164 (30.49%), Postives = 82/164 (50.00%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAI-PNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSL 1429
            +T   +L+L  + I  I P        L +L+L+ NR   +P++I +L  L  L+L  N L +I   + +L  L     ++  I  IP  +   KNL+Q  L  NNI  +P    H   L++L+++GN I+ F   F NL+L     E    +PLF ++  F++
Sbjct:   82 LTSLKNLHLFGNRICRIAPGVFNGLHRLIMLNLNDNRLTSLPQEIGRLRSLTYLSLNRNNLTVIPKELCSLEHLSELHLNYNQIVYIPEEIKFLKNLQQLFLVRNNIEELPEEICHLEKLRVLDIAGNVIQIFPAGFQNLRLTEFYCEG---NPLFLKRPFFAV 242          
BLAST of SMED30033541 vs. Ensembl Mouse
Match: Lrrc69 (leucine rich repeat containing 69 [Source:MGI Symbol;Acc:MGI:1920564])

HSP 1 Score: 66.6254 bits (161), Expect = 1.921e-11
Identity = 50/164 (30.49%), Postives = 82/164 (50.00%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAI-PNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSL 1429
            +T   +L+L  + I  I P        L +L+L+ NR   +P++I +L  L  L+L  N L +I   + +L  L     ++  I  IP  +   KNL+Q  L  NNI  +P    H   L++L+++GN I+ F   F NL+L     E    +PLF ++  F++
Sbjct:   82 LTSLKNLHLFGNRICRIAPGVFNGLHRLIMLNLNDNRLTSLPQEIGRLRSLTYLSLNRNNLTVIPKELCSLEHLSELHLNYNQIVYIPEEIKFLKNLQQLFLVRNNIEELPEEICHLEKLRVLDIAGNVIQIFPAGFQNLRLTEFYCEG---NPLFLKRPFFAV 242          
BLAST of SMED30033541 vs. Ensembl Mouse
Match: Lrrd1 (leucine rich repeats and death domain containing 1 [Source:MGI Symbol;Acc:MGI:3045299])

HSP 1 Score: 67.3958 bits (163), Expect = 2.893e-11
Identity = 63/230 (27.39%), Postives = 109/230 (47.39%), Query Frame = 2
Query:  899 YQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLK----LESIGLENTWIHPLFWRKGEFSLDEFEYS---WAFCDLCDQIISDRSINYISFTKKFNHILPILMSFCSTL 1564
            Y ++T    SL  C +     LNL+ + I ++P  V   +NL  L + +N+   +  +I+QL  ++ L+LA+N L+ I   I N   L+       L+ SIP  +  C NLE   LS NNI  +P  +    NL+ L+++ N +    +  ++L     LE  G + T +        + +  E  Y+   +    LC    + +S++Y+SF   +   +P+ MSF   L
Sbjct:  283 YNQLTIFSKSL--CFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHVPIEIKNCRKITRVELNYNNIMYFPVGLC----ALQSLDYLSFNGNYISEIPVDMSFSKQL 506          

HSP 2 Score: 63.5438 bits (153), Expect = 4.563e-10
Identity = 47/145 (32.41%), Postives = 75/145 (51.72%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK-LESI 1372
            + G   L+L  + +S+IP  +++F NL+IL+ SYN    IP+++ QL  +  L L +N +  +   + +L  L++      ++T IP  L S KNL   +L YN +      +     L  LNL+GN I    K    LK LES+
Sbjct:  181 LLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEISQIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIPDSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESL 325          

HSP 3 Score: 57.3806 bits (137), Expect = 4.158e-8
Identity = 42/145 (28.97%), Postives = 76/145 (52.41%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNN---INAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNLK 1360
            C +T   +L+L+ + I  IP+ +    +L +L LS N+F+  P+++  L  L  L+++ N LQ I   I+ L  ++    S  + T+ P  L   + LE+ ++S  +   +  +P    H + LKILN+S N I+   K+   L+
Sbjct:  524 CSLTNLEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFPKELCSLKNLRVLDISENKLQKIPLEISKLKRIQKLNLSNNIFTNFPVELCQLQTLEELNISQTSGKKLTRLPEEVSHMTQLKILNISNNAIKDIPKNIGELR 668          

HSP 4 Score: 54.6842 bits (130), Expect = 2.473e-7
Identity = 41/149 (27.52%), Postives = 78/149 (52.35%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTN-LKLESIGLENTWIHPL 1402
            L+L  + ++ IP+ +   +NLRIL+L YN+  +  + +  L  L SLNL  N +  +   +  L +L+S +     +T +   +F    +++  L+ N + AI P ++    L++LNL  N ++   K  ++ + LES+ L +  I  L
Sbjct:  256 LSLGKNMLTYIPDSLSSLKNLRILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTFLAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLESLSLSDNNIEEL 404          
BLAST of SMED30033541 vs. Ensembl Mouse
Match: Lrrc8d (leucine rich repeat containing 8D [Source:MGI Symbol;Acc:MGI:1922368])

HSP 1 Score: 65.855 bits (159), Expect = 1.035e-10
Identity = 52/157 (33.12%), Postives = 82/157 (52.23%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHL--LESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYF-KKSFTNLKLESIGLENTWIHPL 1402
            M     L L +  +  IP+ +    NL+ LDL  N  + I E I   HL  L  L L +N +  I  SIT++ +L+S   S   + S+P+ +FS + L   D+SYNNI+ IP  + +  NL+ L+++GN +    K+ F  +KL ++ L    I  L
Sbjct:  635 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVAIPPSITHVKNLESLYFSNNKLESLPTAVFSLQKLRCLDVSYNNISTIPIEIGLLQNLQHLHITGNKVDILPKQLFKCVKLRTLNLGQNCIASL 791          
BLAST of SMED30033541 vs. UniProt/SwissProt
Match: sp|Q05C16|LRC63_HUMAN (Leucine-rich repeat-containing protein 63 OS=Homo sapiens OX=9606 GN=LRRC63 PE=2 SV=2)

HSP 1 Score: 104.76 bits (260), Expect = 1.915e-22
Identity = 65/184 (35.33%), Postives = 93/184 (50.54%), Query Frame = 2
Query:  866 GGSIKQEIEDPYQEITP-TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWR 1411
            G   K      Y+ IT  T ++++ C + GR  LNL    I   P+   +   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F LIT +P GLFS   LE+ D+SYN +  IP+ +    +L+ L + GN + +F      L L  I  EN + HP FWR
Sbjct:  294 GEGFKTVAATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWR 477          
BLAST of SMED30033541 vs. UniProt/SwissProt
Match: sp|Q4V8G0|LRC63_RAT (Leucine-rich repeat-containing protein 63 OS=Rattus norvegicus OX=10116 GN=Lrrc63 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 3.680e-20
Identity = 57/165 (34.55%), Postives = 84/165 (50.91%), Query Frame = 2
Query:  917 TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFW 1408
            T ++++ C + GR  LN     ++  P+   V   L  L+LSYN     P ++  L  L+ L L NNP++ I   I  L  L+ F  +F  ITS+P+GLF    LE+ D+SYN I  IP+ +    +L+ L + G  I  F      L L  +  ENT+  P FW
Sbjct:  323 TTLAIINCQIYGRNALNFKGFFLAQCPDLTSVAFQLVYLNLSYNDLHQFPGEVLYLQNLQVLKLRNNPIREIPSEIQQLKYLRKFTIAFNFITSLPAGLFCLNYLEELDVSYNEIENIPNEIQKLRSLEKLTVDGTNITAFPPGILKLNLVKLEFENTFTIPPFW 487          
BLAST of SMED30033541 vs. UniProt/SwissProt
Match: sp|A6H694|LRC63_MOUSE (Leucine-rich repeat-containing protein 63 OS=Mus musculus OX=10090 GN=Lrrc63 PE=2 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 7.705e-17
Identity = 57/165 (34.55%), Postives = 84/165 (50.91%), Query Frame = 2
Query:  917 TKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFW 1408
            T ++++ C + GR  LNL    ++  P+   V   L  L+LS+N     P +I  L  L+ L L NNP++ I   I  L  L+ F  +F  IT +P GLF    LE+ D+SYN I  I + +    +L+ L + GNPI  F      L L  + +ENT+    FW
Sbjct:  356 TTLAIINCQIYGRNALNLKGFFLANCPDLTPVAFQLVYLNLSFNDLNQFPIEILYLQNLQVLKLRNNPIKEIPSEIHLLTYLRIFSIAFNYITKLPDGLFCLNYLEELDVSYNEIENISNEIQKLRSLEKLIVDGNPITSFPPGILKLNLIKLQIENTFTCSQFW 520          
BLAST of SMED30033541 vs. UniProt/SwissProt
Match: sp|A8JAM0|DRC7_CHLRE (Dynein regulatory complex subunit 7 (Fragment) OS=Chlamydomonas reinhardtii OX=3055 GN=DRC7 PE=1 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 2.633e-13
Identity = 54/178 (30.34%), Postives = 91/178 (51.12%), Query Frame = 2
Query:  830 DILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            D+L++ LM A     +        +++ P  V L++      T L LSS+ ++ +P+ +E F+ LRIL L YN+ K IP  +Y+L  L   + + N +Q +DD+I +L+ LK    S   IT++P  L +   LE   +  N +  +P  +     +  ++LS N +RY   S   LK
Sbjct:   14 DVLEERLMEARRTYRLNMGYAG-LKQLPPGFVELVKKYNPHITELELSSNDLTDLPDELEEFRYLRILRLKYNQLKRIPAVVYRLPQLMVFDASGNRIQKVDDAIGHLSLLKELDVSGNEITTLPESLSTLPKLEVLQVENNRLELLPESLGELPGVIKMDLSTNNLRYLPASMGQLK 190          
BLAST of SMED30033541 vs. UniProt/SwissProt
Match: sp|B0W6M9|SUR8_CULQU (Leucine-rich repeat protein soc-2 homolog OS=Culex quinquefasciatus OX=7176 GN=Sur-8 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 3.951e-11
Identity = 54/198 (27.27%), Postives = 104/198 (52.53%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIH--PLFWRKGEFSLDEFEYSW-AFCDLCDQIISDRS-INYISFTKKFNHILP 1537
            L L+ +S++++P+ ++  + L++LDL +N+   IP+ IY+LH L +L L  N ++++ D++ NL+SL         I  +P+ +   +NL   DLS+N++  +P  +    NL  L+L  N +    ++  NL  L+ +GL    +   P+  R     +DEF     +   L D +++  S +  I+ ++   H  P
Sbjct:  198 LALNENSLTSLPDSLQNLKALKVLDLRHNKLSEIPDVIYKLHTLTTLYLRFNRIKVVGDNLKNLSSLTMLSLRENKIHELPAAIGHLRNLTTLDLSHNHLKHLPEAIGNCVNLTALDLQHNDLLDIPETIGNLANLQRLGLRYNQLTAIPVSLRNC-IHMDEFNVEGNSISQLPDGLLASLSNLTTITLSRNAFHSYP 394          

HSP 2 Score: 59.6918 bits (143), Expect = 5.273e-8
Identity = 47/156 (30.13%), Postives = 82/156 (52.56%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH--VDVHSNLKILNLSGNPIRYFKKS----FTNLKLESIGLENTWI 1393
            ++  T L+L  + I  +P  +   +NL  LDLS+N  K +PE I     L +L+L +N L  I ++I NL +L+     +  +T+IP  L +C ++++ ++  N+I+ +P   +   SNL  + LS N    +       FTN+   SI +E+  I
Sbjct:  261 LSSLTMLSLRENKIHELPAAIGHLRNLTTLDLSHNHLKHLPEAIGNCVNLTALDLQHNDLLDIPETIGNLANLQRLGLRYNQLTAIPVSLRNCIHMDEFNVEGNSISQLPDGLLASLSNLTTITLSRNAFHSYPSGGPAQFTNVT--SINMEHNQI 414          

HSP 3 Score: 52.7582 bits (125), Expect = 7.588e-6
Identity = 44/171 (25.73%), Postives = 83/171 (48.54%), Query Frame = 2
Query:  950 GRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSLDEFEYSWAFC 1459
            G T LN+  ++++++P  +  +  +  L+   N    +P+ I+ L  LE L L+NN L+ I ++I NL  L+        + S+PS +    +L++  L  N + ++P    H +NL  L++  N ++Y  +    L+     LE+ +I+         SL +  Y  A C
Sbjct:  427 GLTKLNMKENALTSLPLDIGTWSQMVELNFGTNSLAKLPDDIHCLQNLEILILSNNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEIGLLHDLQKLILQSNALQSLPRTIGHLTNLTYLSVGENNLQYLPEEIGTLE----NLESLYIN------DNASLVKLPYELALC 587          
BLAST of SMED30033541 vs. TrEMBL
Match: W5MWW0 (Uncharacterized protein OS=Lepisosteus oculatus OX=7918 PE=4 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 1.070e-25
Identity = 100/372 (26.88%), Postives = 169/372 (45.43%), Query Frame = 2
Query:  602 IPVPYKSIPKHIIIIQLAALLKYQLSN----------DSNKIVSCTVKSLARKGRFPQSSNPXXXXXXXXXXXXXXXXSITPNKISDILQKDLMNASAGGSIKQEI----EDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHS--NLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGE-----------------FSLDEFEYSWAF-----------CDLCDQIISDRSINYISFTKKFNHI--LPILMSFCSTLCRDSL 1579
            +PV  K  P+  II +LAAL++ Q+ +          D +  V C  K ++  G+                E L  L S   +  S+I+   +      GS + +     +D    I P+++++++C++ G   L+L +H I+ +P+   +  +L  L+LS+N   + P ++Y +  LE L L +NP++ I D I  L+ LK+F+ SF LI+++P GLFS   L+  D+SYN I+AIP  D+ +   L+ LN+ GN +         L L  + + N ++HP FW +                   + LD    S              CD C   +    +  I   +K   +  +P L S CS  C +S 
Sbjct:  178 VPVATKRTPQRQIIYELAALIREQVRSQTSAKSSHREDRDSAVGCGSKRVSISGQ---------------REALQTLSSSQEHPGSEIILNSVTTRYFQGSRRSQSPFLQDDQCGVIGPSELAILDCLVQGGVLLSLKAHFIARVPDLTPLAHSLLYLNLSFNELNVFPTEVYDIPCLEVLKLRDNPIKEIPDGIHKLSKLKTFVISFCLISALPLGLFSLPCLQFLDVSYNMISAIPS-DMRNLRALEYLNVEGNQLAALPCGALRLCLRELRVSNNYMHPYFWTENTQNQPQRLVHLAALCFSVYGLDRRYTSLPCDIQQTLNNVNTCDCCRGPLFGPGLRLIRPCEKIFGVRKVPFLFSACSPSCYESF 533          
BLAST of SMED30033541 vs. TrEMBL
Match: R7UUV9 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_209667 PE=4 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 1.592e-25
Identity = 90/327 (27.52%), Postives = 165/327 (50.46%), Query Frame = 2
Query:  479 QQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPXXXXXXXXXXXXXXXXSITPNKI---SDILQKDLMNASAGGSIK-----QEIEDPYQE-----ITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIHPLFWRK 1414
            ++ K+I +S    K+ +KL     + +      I  QI  ++  P   IP+  +++++AAL++ Q+S   +  ++  ++ L R   +  S  P       E   L       P ++   +++  KD +    GG  K          P+       I+PT++++++ +M G   L+L +H IS +P+   +   +  L+LS+N F++ P ++  +  L +L L NNPL+ +   I  L +LK+ + SF +I+S+P GLF  K L+  D+SYN I+ IP+ +    NL  LNL GN +         L  L+ + + N ++HPLFW++
Sbjct:  205 EKTKKIVLSRHNYKQIQKLIQRQYQSQPTEISTIDMQIPDEVCKPSSRIPQRQLLVEMAALVREQISQVMDMDMTTIIRPLPR---YSPSHKPGSSAPHTEIVLLENSPGQGPRRLLQDTELPGKDGL--FQGGHAKYFQGSGRSTSPFGSENDGMISPTEIAVLDSLMNGGVALSLKAHFISDLPDIDPLANTITYLNLSFNDFRIFPYEVISMSQLVTLKLRNNPLKELPADIYKLKNLKTLVFSFCVISSVPIGLFQLKRLKHLDMSYNKISFIPNEIRNLENLTELNLEGNELAAMPAGALRLPGLQYLKVRNNFMHPLFWKE 526          
BLAST of SMED30033541 vs. TrEMBL
Match: V3ZNH6 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_232977 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 9.763e-25
Identity = 70/250 (28.00%), Postives = 126/250 (50.40%), Query Frame = 2
Query:  908 ITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKG--------------------EFSLDEFEYS-------WAFCDLCDQIISDRSINYISFTKKFNHI--LPILMSFCSTLC 1567
            ITP+++++++ +++G + L+L +H IS +P+   + + +  L+LS+N F  +PE++  +H L+   + NNPL ++ D I  L  L++ + SF LI++IP+ L+  + LE  +LSYN + +I + +    NL  LN+ GN +         L L+ + ++N ++HPLFW++                      + L +   S          CD C Q +  + I  I    K   I  LP +   CS  C
Sbjct:  361 ITPSELAILDALISGGSALSLKAHFISELPDIAPMVKTITYLNLSFNDFTSVPEEVLDIHQLQIFKMRNNPLLVLPDDIDRLCCLRTLVVSFCLISTIPNSLYKLQTLEHVNLSYNKLTSISNDIKYMKNLVELNIEGNQLPAMPCGALTLNLQYLNVKNNFMHPLFWKEHTDNMPQTLCDLSVLCLYKSERYQLKDLPDSVQTLYKKAGKCDCCHQAMFGQGIKIIRPVSKIYGIKNLPFIFRACSLSC 610          
BLAST of SMED30033541 vs. TrEMBL
Match: A0A2B4SB99 (Leucine-rich repeat-containing protein 63 OS=Stylophora pistillata OX=50429 GN=Lrrc63 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 3.295e-24
Identity = 82/277 (29.60%), Postives = 132/277 (47.65%), Query Frame = 2
Query:  833 ILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRK---------GEFS-------------------LDEFEYSWAFCDLCDQIISDRSINYISFTKKFNHI--LPILMSFCSTLCR 1570
            +L+ DL  A   G +         +++P +  ++  +MTG + LNL +H ++ +P+   +   L  L+LS+N   + P +I QL  L SL L NNP++ I   I  L  L  F  SF L+TS+PS LF  K+LE  DL+YN ++ IP  ++  S+L+ LNL GN +        +L+L+ + ++N + HPL WR+         G+ +                   +     S+  CD CD  +    +  I        I  LP L + C+  CR
Sbjct:  354 MLEIDLTVAHLSGDVYD------AQMSPMEAVVLNAMMTGSSILNLRAHFLNQLPDMSPLAGMLTHLNLSFNDLWVFPPEILQLVNLVSLKLRNNPIKEIPHGIKQLKRLTVFEMSFNLLTSLPSSLFQLKHLELLDLAYNWLSFIPSDIENLSSLRELNLEGNRLGALPVGALHLRLKYVRIQNNFTHPLMWRETATNQPQRLGDLAALVVFGQGLHIKNRDLPPEIKNILESYTRCDCCDGPMFGPGVRLIKAPASIFGIKNLPFLFNACTQTCR 624          
BLAST of SMED30033541 vs. TrEMBL
Match: A0A267EK01 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033922g1 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 3.637e-24
Identity = 63/176 (35.80%), Postives = 103/176 (58.52%), Query Frame = 2
Query:  905 EITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHS--NLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFS 1426
            +I+P ++ +++C++TG   L+L ++ ISA+P+   +   L  ++LSYN FK IP  I+QL  L+ L L +NPL I+   I  L  L+S + SF LIT+IP  L+  K L   D+SYN I+ + H ++    NL  LN+ GN +     +   ++L+ I + N ++HP  W +   S
Sbjct:  318 QISPAEICVLDCMLTGGIALSLKANFISALPDVSVLRHTLTYVNLSYNDFKEIPPAIFQLPSLQILKLRSNPLSILSSDIELLTQLESLVVSFCLITTIPVSLYKLKKLRILDVSYNKISFL-HREIKGLRNLTYLNVEGNELTSLPNTMLAMRLKRIKVRNNFLHPFLWAENSLS 492          
BLAST of SMED30033541 vs. Ensembl Cavefish
Match: ENSAMXT00000013227.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000129.1:105044:112349:-1 gene:ENSAMXG00000012867.2 transcript:ENSAMXT00000013227.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.9669 bits (219), Expect = 1.637e-18
Identity = 56/166 (33.73%), Postives = 95/166 (57.23%), Query Frame = 2
Query:  908 ITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSFTNLKLES-IGLENTWIHP 1399
            I+ T+++++EC+    T LNL +H IS +P+   + QNL  L+LS+N F + P ++ +L  LE L L +NP++ I   I  L +LK+ I SF  I S+PS L+   +L+  D+SYN I+++   +    +L+ L++ GN +         L+  S + L   + HP
Sbjct:  279 ISLTELAIIECLTKHGTSLNLKAHFISQLPDLFLLRQNLLYLNLSFNSFTVFPVEVCELARLEVLKLRDNPIEEIPADIQKLLNLKTLIISFCKIRSLPSQLYHLTSLQHLDVSYNLISSLSSEIKNLRSLQYLSVEGNQVEALPVGVVYLRCVSELRLGGNYTHP 444          
BLAST of SMED30033541 vs. Ensembl Cavefish
Match: lrrc57 (leucine rich repeat containing 57 [Source:NCBI gene;Acc:107197332])

HSP 1 Score: 64.3142 bits (155), Expect = 2.851e-11
Identity = 38/112 (33.93%), Postives = 63/112 (56.25%), Query Frame = 2
Query:  944 MTG--RTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            +TG  RT ++LS++ I  +P F+  FQ L+ L ++ N+   +P  I +L  LE+L L  N LQ +  ++  L +L++   S       P GL + + L+  DLS N+I A+P
Sbjct:   36 LTGNLRT-VDLSNNKIEVLPAFIGSFQQLKSLTIASNKLTSLPNDIGKLKKLETLVLNGNQLQQLPAAVGQLKALRTLSLSGNQFREFPGGLGTLRQLDMLDLSKNHIQAVP 146          

HSP 2 Score: 48.9062 bits (115), Expect = 3.987e-6
Identity = 36/129 (27.91%), Postives = 59/129 (45.74%), Query Frame = 2
Query: 1019 NLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPL 1402
            NLR +DLS N+ +++P  I     L+SL +A+N L  + + I  L  L++ + +   +  +P+ +   K L    LS N     P  +     L +L+LS N I+        L+   I L    I  L
Sbjct:   39 NLRTVDLSNNKIEVLPAFIGSFQQLKSLTIASNKLTSLPNDIGKLKKLETLVLNGNQLQQLPAAVGQLKALRTLSLSGNQFREFPGGLGTLRQLDMLDLSKNHIQAVPAGVAELQAIEINLNQNQISAL 167          
BLAST of SMED30033541 vs. Ensembl Cavefish
Match: lrrc57 (leucine rich repeat containing 57 [Source:NCBI gene;Acc:107197332])

HSP 1 Score: 63.929 bits (154), Expect = 5.957e-11
Identity = 38/112 (33.93%), Postives = 63/112 (56.25%), Query Frame = 2
Query:  944 MTG--RTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            +TG  RT ++LS++ I  +P F+  FQ L+ L ++ N+   +P  I +L  LE+L L  N LQ +  ++  L +L++   S       P GL + + L+  DLS N+I A+P
Sbjct:   36 LTGNLRT-VDLSNNKIEVLPAFIGSFQQLKSLTIASNKLTSLPNDIGKLKKLETLVLNGNQLQQLPAAVGQLKALRTLSLSGNQFREFPGGLGTLRQLDMLDLSKNHIQAVP 146          

HSP 2 Score: 48.521 bits (114), Expect = 7.285e-6
Identity = 36/129 (27.91%), Postives = 59/129 (45.74%), Query Frame = 2
Query: 1019 NLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPL 1402
            NLR +DLS N+ +++P  I     L+SL +A+N L  + + I  L  L++ + +   +  +P+ +   K L    LS N     P  +     L +L+LS N I+        L+   I L    I  L
Sbjct:   39 NLRTVDLSNNKIEVLPAFIGSFQQLKSLTIASNKLTSLPNDIGKLKKLETLVLNGNQLQQLPAAVGQLKALRTLSLSGNQFREFPGGLGTLRQLDMLDLSKNHIQAVPAGVAELQAIEINLNQNQISAL 167          
BLAST of SMED30033541 vs. Ensembl Cavefish
Match: lrrc1 (leucine rich repeat containing 1 [Source:NCBI gene;Acc:103023999])

HSP 1 Score: 64.6994 bits (156), Expect = 1.556e-10
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            T L +S + I A+P  +   + L IL    NR   +PE I     L  L L  N L  +  SI  L  L +F C    +TS+P  +  C +L    +  N ++ IP  +   + L + ++SGN + +   S T L+L+++ L +    PL 
Sbjct:  246 TDLLVSQNLIDALPEGIGKLKRLSILKADQNRLVQLPESIGSCESLTELVLTENHLMSLPRSIGKLKKLSNFNCDRNRLTSLPKEIGGCSSLNVLCVRDNRLSRIPSELSQATELHVFDVSGNRLAFLPMSLTTLRLKALWLSDNQSQPLL 396          

HSP 2 Score: 57.7658 bits (138), Expect = 2.371e-8
Identity = 48/140 (34.29%), Postives = 68/140 (48.57%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSN-LKILNLSGNPIRYFKKSFTNLKLESI 1372
            T L+++  S+ A+P+ +    NL  L+L  N    +PE + QL+ LE L+L NN L  + ++I  L SLK        +  IP  L S KNL   DLS N +  +P      N L  L +S N I    +    LK  SI
Sbjct:  131 TCLSINDISLQALPDNIGNLCNLVSLELRENMLTYLPESLCQLNRLEELDLGNNELYNLPETIGCLVSLKDLWLDGNQLAEIPPELGSMKNLLCLDLSENKLERLPEESAGLNSLTDLLVSQNLIDALPEGIGKLKRLSI 270          
BLAST of SMED30033541 vs. Ensembl Cavefish
Match: lrrc1 (leucine rich repeat containing 1 [Source:NCBI gene;Acc:103023999])

HSP 1 Score: 63.5438 bits (153), Expect = 2.664e-10
Identity = 44/151 (29.14%), Postives = 71/151 (47.02%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            T L +S + I A+P  +   + L IL    NR   +PE I     L  L L  N L  +  SI  L  L +F C    +TS+P  +  C +L    +  N ++ IP  +   + L + ++SGN + +   S T L+L+++ L +    PL 
Sbjct:  227 TDLLVSQNLIDALPEGIGKLKRLSILKADQNRLVQLPESIGSCESLTELVLTENHLMSLPRSIGKLKKLSNFNCDRNRLTSLPKEIGGCSSLNVLCVRDNRLSRIPSELSQATELHVFDVSGNRLAFLPMSLTTLRLKALWLSDNQSQPLL 377          
BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009498.1 (pep scaffold:Pmarinus_7.0:GL479116:164966:178398:1 gene:ENSPMAG00000008592.1 transcript:ENSPMAT00000009498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.0485 bits (227), Expect = 6.402e-22
Identity = 60/186 (32.26%), Postives = 103/186 (55.38%), Query Frame = 2
Query:  851 MNASAGGSIKQEIED--PYQEI-TPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKI---LNLSGNPIRYFKKSFTNLKLESIGLENTW 1390
            ++A  GGS + E+    P+  I +P +++++ C++ G T L+L +H I ++P    +   L  L+LSYN  + +P ++ +L  LE L L NNPL  +   +  L+ L + + SF L TS+P  +++  NL   D+SYN+I ++   D   NL+    LN+ GN +     SF +L+L      NT+
Sbjct:    1 LHAVPGGSFQGEVRSRSPFSTIISPAELAVLHCLLQGGTTLSLKAHFIDSLPGLSPLIDTLVYLNLSYNNLRSLPHELLELGGLEVLKLRNNPLSGLPQQLAGLSHLHTLVLSFCLFTSLPQSVYNLPNLRMLDVSYNSITSL--SDDIKNLRFLECLNMEGNHLTELPASFLSLRLREFRANNTF 184          
BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Match: PIDD1 (p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491])

HSP 1 Score: 65.855 bits (159), Expect = 1.681e-11
Identity = 41/117 (35.04%), Postives = 63/117 (53.85%), Query Frame = 2
Query:  977 HSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPI 1327
            H  S  P+ +E    L  LDLS NR + +PE++  LH LE L+++ N L  +  S++ +N LKS       + S+P+ L S   L + DL  N++  +P  +V + L    L GNPI
Sbjct:  164 HLCSVPPSSLEGLSALCWLDLSNNRLETLPEELGSLHCLEDLDVSRNSLASLPASLSGMNRLKSLFLHDNRLISVPASLASLPALSRLDLCNNSLRFVPP-EV-AQLPFTQLKGNPI 278          
BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Match: lrsam1 (leucine rich repeat and sterile alpha motif containing 1 [Source:ZFIN;Acc:ZDB-GENE-060526-97])

HSP 1 Score: 59.3066 bits (142), Expect = 1.507e-9
Identity = 36/132 (27.27%), Postives = 68/132 (51.52%), Query Frame = 2
Query:  980 SISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNLKLESI 1372
            S+++  N ++ F  L++LDL  N+ K +PE+++QL  L+ LN+  N L  + +S+  L  L++       I+ +P  L   ++L   D+S N I+ +P    H   L+ L L    I +  +      +E++
Sbjct:   68 SLTSGGNILD-FSGLKVLDLHANKLKALPEEMWQLSALQVLNVEGNNLMALPESVVRLRQLQTLNVRDNKISELPKDLDGLQSLRNLDISLNQISKLPLSLAHIRTLETLQLDVGRISFPPQDVVRQGIEAV 198          
BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:334130])

HSP 1 Score: 58.5362 bits (140), Expect = 2.633e-9
Identity = 39/143 (27.27%), Postives = 73/143 (51.05%), Query Frame = 2
Query:  923 VSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSF 1348
            +SL  C++   THL+L ++++S++PN +E    L+ + +S NRF+ IP  +Y++  LE+L  ++N + ++D                       +GL S + L   DL  N+I  + P + +  +L+ L L GN  R  + + 
Sbjct:  467 LSLELCMLGNLTHLDLRNNALSSLPNEMEALSRLQSIIISCNRFREIPPVLYRVGTLETLLASDNQIGVVD----------------------ATGLRSLERLGTLDLQNNDITVVPPQLGLCVSLRSLLLGGNRFRSPRPAL 587          

HSP 2 Score: 49.2914 bits (116), Expect = 1.650e-6
Identity = 35/136 (25.74%), Postives = 74/136 (54.41%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            T L L+S+ + A+ + +++   L +LD+  N+   +P+ + +L  L+ LN+++N LQ + +S+  ++SL S       +  I + + +   LE+ DLS N + A+P  +   + +  LN++ N +R       ++K
Sbjct:   87 TKLILASNRLRALSDDLQLLPALTVLDVHDNQLTELPQVLGELVNLQKLNVSHNKLQTLPESLWAISSLLSLHVEHNELEGISNNIGNLARLEELDLSSNRLTALPGTLGKLTRVTKLNVAENKLRELPTEIKSMK 222          
BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Match: scrib (scribble planar cell polarity protein [Source:NCBI gene;Acc:368473])

HSP 1 Score: 56.9954 bits (136), Expect = 8.321e-9
Identity = 43/154 (27.92%), Postives = 73/154 (47.40%), Query Frame = 2
Query:  902 QEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            Q + P   + M  V      L++S + I+ IP+ +++   L ++D S N    +PE   QL  L  L+L +  LQ + D I NL++L +      L+ ++P+ L     LEQ DL  N +  +P  +    N++ L L GN +         L+
Sbjct:   19 QRLPPDIANFMHLV-----DLDMSRNDIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELR 167          

HSP 2 Score: 48.9062 bits (115), Expect = 2.948e-6
Identity = 28/105 (26.67%), Postives = 55/105 (52.38%), Query Frame = 2
Query:  959 HLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            +L+L+  S+  +P+ +    NL  L+L  N  K +P  ++ L  LE L+L NN L+ +  S+ +L +++        + ++PS +   + L   D+S N +  +P
Sbjct:   79 YLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLP 183          
BLAST of SMED30033541 vs. Ensembl Yeast
Match: CYR1 (Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000003542])

HSP 1 Score: 48.9062 bits (115), Expect = 1.787e-6
Identity = 38/133 (28.57%), Postives = 64/133 (48.12%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            L L  + I  +PN +    NL IL+L  N  + +P    +L  L+ L+L++N      + I    +L     S+  I S+P        L + +LS+N +N I  +   ++L+ LNL  N I   K + +NL+
Sbjct:  868 LELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASNLQ 1000          
BLAST of SMED30033541 vs. Ensembl Nematostella
Match: EDO39345 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAC1])

HSP 1 Score: 108.997 bits (271), Expect = 3.628e-25
Identity = 70/197 (35.53%), Postives = 114/197 (57.87%), Query Frame = 2
Query:  827 SDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRK 1414
            S + ++  +  +A GS+  E  D   ++TP +  ++  ++T    LN+ +H ++ +P+  ++   L  L+ S+N F + P +I +L +L SL L NNP++ I + I NL+ LK F  SF L+TS+P+ LF  K+LE  DLSYN ++ IP  +     L+ LNL GN +     S   L L+   + N +IHPLFWR+
Sbjct:  275 SSLRKQQEIRKNADGSVGAE--DYSDQVTPLEAVILNAIVTESAVLNVKAHFLNRLPSLSQLVDTLTHLNASFNDFWVFPPEILELKMLVSLKLRNNPIKAIPNGIGNLSQLKVFEMSFNLLTSLPASLFELKDLELLDLSYNRLSFIPADIGKLRALRELNLEGNQLGAMPISTLFLPLKYFRISNNFIHPLFWRE 469          
BLAST of SMED30033541 vs. Ensembl Nematostella
Match: EDO48217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKB1])

HSP 1 Score: 64.6994 bits (156), Expect = 4.939e-11
Identity = 44/135 (32.59%), Postives = 71/135 (52.59%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            T L L+S+S++ I   V     L +LD+  N    +PE+I  L  L+ LNL +N +  +  S+  L SL S         S+   L S +NLE+ D+SYN ++++P +    +L+ LNLS N +      F +L+
Sbjct:   80 TKLILASNSLTEISGDVFNLPALVLLDIHDNSLTTLPEEIGSLSCLQKLNLGHNKISSLPMSMAQLESLCSLKLEHNSFKSLECWLGSLRNLEELDVSYNMVSSLPSLAGLKHLRTLNLSNNALEMLPPEFDHLQ 214          

HSP 2 Score: 57.3806 bits (137), Expect = 9.135e-9
Identity = 42/129 (32.56%), Postives = 69/129 (53.49%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSI-TNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKK 1342
            LN+SS+ I   P  +   ++LR LD   N    +P  + Q   L+ L LA N +  +D  +    + L        L+TSIP  +   ++LE+ DL+ N+I+ +P+ +   SNLK L L+GNP+R  ++
Sbjct:  219 LNISSNKICNFPGKLYNMKSLRRLDCRQNHLTSVP-SVGQCPSLKELYLAYNKIAELDSKVFAGYSGLTVLDLHDNLLTSIPEDIIILRDLERLDLTNNDISGLPYKIGNMSNLKSLVLNGNPLRELRR 346          

HSP 3 Score: 52.7582 bits (125), Expect = 2.870e-7
Identity = 38/138 (27.54%), Postives = 61/138 (44.20%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKSF 1348
            C  T    L+L ++ +S++P+     ++LR + +SYNRF  +P  +Y +  L +L   +N + +ID                        GL     LE  DL  NNI+ + P +     LK L L GNP R  + + 
Sbjct:  469 CSFTQLEFLDLRNNQLSSLPDGFASLRSLREIIISYNRFSCLPPVLYSMTSLRTLLACDNQIAVID----------------------VDGLLRMSVLETLDLQNNNISQVPPELGNVRGLKALQLGGNPFRTPRAAI 584          

HSP 4 Score: 50.8322 bits (120), Expect = 1.227e-6
Identity = 37/122 (30.33%), Postives = 64/122 (52.46%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPI 1327
            L L  +S  ++  ++   +NL  LD+SYN    +P  +  L  L +LNL+NN L+++     +L +L     S   I + P  L++ K+L + D   N++ ++P V    +LK L L+ N I
Sbjct:  151 LKLEHNSFKSLECWLGSLRNLEELDVSYNMVSSLP-SLAGLKHLRTLNLSNNALEMLPPEFDHLQALDDLNISSNKICNFPGKLYNMKSLRRLDCRQNHLTSVPSVGQCPSLKELYLAYNKI 271          
BLAST of SMED30033541 vs. Ensembl Nematostella
Match: EDO34345 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPM2])

HSP 1 Score: 56.225 bits (134), Expect = 6.631e-9
Identity = 44/143 (30.77%), Postives = 73/143 (51.05%), Query Frame = 2
Query:  929 LMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSI-TNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKI-LNLSGNPIRYFKKSFT 1351
            L+    T RT L+LS + +  +P+ +     L+ + LS NR + +P  + +L  LE L L NN L+++   + TNL  LK+   +   IT+ P  + S ++L+  DLS N + A+P   +     + LNL+ N I     S  
Sbjct:   32 LLRLGATLRT-LDLSDNKLKVLPSAIGNLTGLKNMTLSSNRLETLPSDLGKLKKLEVLMLNNNNLKVLPVGLFTNLTHLKTVSLASNQITAFPEDMCSLRHLDVIDLSDNKLQALPDGKMGQVQAVELNLNSNQISVLPASLA 173          

HSP 2 Score: 47.3654 bits (111), Expect = 5.535e-6
Identity = 37/119 (31.09%), Postives = 66/119 (55.46%), Query Frame = 2
Query: 1061 IPEQIYQLHL-LESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSN---LKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIHPL 1402
            IP+ + +L   L +L+L++N L+++  +I NL  LK+   S   + ++PS L   K LE   L+ NN+  +P V + +N   LK ++L+ N I  F +   +L+ L+ I L +  +  L
Sbjct:   28 IPQPLLRLGATLRTLDLSDNKLKVLPSAIGNLTGLKNMTLSSNRLETLPSDLGKLKKLEVLMLNNNNLKVLP-VGLFTNLTHLKTVSLASNQITAFPEDMCSLRHLDVIDLSDNKLQAL 145          
BLAST of SMED30033541 vs. Ensembl Nematostella
Match: EDO37102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGP5])

HSP 1 Score: 56.6102 bits (135), Expect = 2.290e-8
Identity = 44/157 (28.03%), Postives = 84/157 (53.50%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQ-IYQLHLLESLNLANNPLQIIDDSITN-LNSLKSFICSFTLITS-----IPSGLFSCKNLEQADLSYNNINAIPHVDVHS--NLKILNLSGNPIRYFKKSFTNLKLESIGLENT 1387
            + G T L+++ ++I ++P+     + L+ LD+S+N  + IPE+ + +L +L +LN+++N L+ + +S+   L +LK    S+  +       IP  +    NL++ DLS N +  +P  +  +   LK L L+ N            K++SI LEN+
Sbjct: 1068 LPGLTKLSVAGNNIKSLPSTALAVRRLKDLDISHNHIESIPEEFLKELFILNTLNVSHNSLESLPESVAPFLQNLKILKMSYNNLAGKSRFHIPRFILMLPNLKELDLSNNKLTHVPPPEAWTTRQLKELILAHN------------KIKSISLENS 1212          

HSP 2 Score: 54.299 bits (129), Expect = 1.267e-7
Identity = 49/134 (36.57%), Postives = 71/134 (52.99%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVF-QNLRILDLSYN------RFKLIPEQIYQLHLLESLNLANNPL-QIIDDSITNLNSLKSFICSFTLITSIP----SGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNP 1324
            LN+S +S+ ++P  V  F QNL+IL +SYN      RF  IP  I  L  L+ L+L+NN L  +          LK  I +   I SI     +G +S  NLE+  LS+NN+  +P  +   ++L  L+LS NP
Sbjct: 1121 LNVSHNSLESLPESVAPFLQNLKILKMSYNNLAGKSRFH-IPRFILMLPNLKELDLSNNKLTHVPPPEAWTTRQLKELILAHNKIKSISLENSTGKWS--NLERLVLSHNNLKCVPRGIGDLTSLTSLDLSYNP 1251          

HSP 3 Score: 51.9878 bits (123), Expect = 6.004e-7
Identity = 47/161 (29.19%), Postives = 73/161 (45.34%), Query Frame = 2
Query:  929 LMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPE--QIYQLHLLESLNLANNPLQIIDDSITN-LNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHS--NLKILNLSGNPIRYFKKS----FTNLKLESIGLEN 1384
            L+   M    H+NLS +     P  +   + L+ LDLSYN+    P    I    LLE L+LA+N L    + +   L  L     +   I S+PS   + + L+  D+S+N+I +IP   +     L  LN+S N +    +S      NLK+  +   N
Sbjct:  991 LLHEAMPKLEHMNLSHNEFETFPYCLVKCKRLKSLDLSYNKLTNSPPPLSISASILLEDLSLAHNVLDSFPEWLGEFLPGLTKLSVAGNNIKSLPSTALAVRRLKDLDISHNHIESIPEEFLKELFILNTLNVSHNSLESLPESVAPFLQNLKILKMSYNN 1151          
BLAST of SMED30033541 vs. Ensembl Nematostella
Match: EDO33964 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQP8])

HSP 1 Score: 53.9138 bits (128), Expect = 4.316e-8
Identity = 34/107 (31.78%), Postives = 61/107 (57.01%), Query Frame = 2
Query:  950 GRTHLNLSSHSISAIPNF--VEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNIN 1264
            G T L+L    IS++ +   +   ++L  L LS+N+   +P+ I +L  LE+L L NN ++ +  ++ +L  L+    +   ++S+P GL +   LE  DL+YNN+N
Sbjct:   16 GYTELDLCDKGISSLNDISNLTTARHLVRLTLSHNKITSLPQAIVELQNLETLILFNNHIEELPIALGSLPKLRHLNVAVNRLSSLPKGLGTASALEILDLTYNNLN 122          
BLAST of SMED30033541 vs. Ensembl Medaka
Match: lrrc1 (leucine rich repeat containing 1 [Source:NCBI gene;Acc:101169728])

HSP 1 Score: 65.4698 bits (158), Expect = 6.170e-11
Identity = 46/151 (30.46%), Postives = 72/151 (47.68%), Query Frame = 2
Query:  956 THLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLF 1405
            T L +S +SI A+P  +   Q L IL +  NR   +PE I     L  L L  N ++ +  SI  L  L +  C    +TS+P  +  C +L    +  N +  IP  +   + L +L++SGN + Y   S T L+L+++ L      PL 
Sbjct:  196 TDLLVSQNSIEALPESIGKLQKLSILKVDQNRLNCLPESIGSCESLAELILTENQIKSLPRSIGKLKKLFNLNCDRNQLTSLPKEIGGCCSLNVFCMRDNRLTRIPAELSQATELHVLDVSGNRLAYLPLSLTTLQLKALWLSENQSQPLL 346          
BLAST of SMED30033541 vs. Ensembl Medaka
Match: lrrc8ab (volume-regulated anion channel subunit LRRC8A [Source:NCBI gene;Acc:101162605])

HSP 1 Score: 63.1586 bits (152), Expect = 4.291e-10
Identity = 55/165 (33.33%), Postives = 76/165 (46.06%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQI--YQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYF-KKSFTNLKLESIGLENTWIHPLFWRKGEFS 1426
            M   T L L    +  IP+ +    NL+ +DL  N  K I E I    LH L  L L  N +  I   I  LN+L+    +   I  IPS LF C+ L   DLS+NN+ +IP  +    NL  L ++ N I     + F   KL ++ L N  +  L  R GE +
Sbjct:  575 MVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLVCLKLWYNQIAYIPIQIGTLNNLEKLYLNRNKIEKIPSQLFYCRKLRILDLSHNNLTSIPADIGFLQNLHYLAVTANRIESLPNELFQCKKLRTLNLGNNCLQSLPSRFGELT 739          

HSP 2 Score: 50.447 bits (119), Expect = 4.184e-6
Identity = 28/95 (29.47%), Postives = 50/95 (52.63%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADL 1246
            L+LS +++++IP  +   QNL  L ++ NR + +P +++Q   L +LNL NN LQ +      L +L         +  +P  L  C+ L++  L
Sbjct:  675 LDLSHNNLTSIPADIGFLQNLHYLAVTANRIESLPNELFQCKKLRTLNLGNNCLQSLPSRFGELTALTQLELRGNRLECLPVELGECRQLKRTGL 769          
BLAST of SMED30033541 vs. Ensembl Medaka
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:101158008])

HSP 1 Score: 62.7734 bits (151), Expect = 5.902e-10
Identity = 41/139 (29.50%), Postives = 71/139 (51.08%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFT 1351
            C +   THL+L ++ +  +P  +E    LR + LSYNRFK  PE +YQ+  +E++ +ANN +  +D                      P+ L   ++L   DLS N++ +IP  + + ++L+ L+L GNP R  + +  
Sbjct:  462 CRLLQLTHLDLRNNQLKDLPADMENLAKLRCIILSYNRFKSFPEVLYQMFSMETVLMANNQVSSVD----------------------PARLARLEHLSTLDLSNNDLLSIPPELGLCTSLRSLSLQGNPFRTPRAAIV 578          

HSP 2 Score: 54.6842 bits (130), Expect = 1.620e-7
Identity = 31/114 (27.19%), Postives = 60/114 (52.63%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHV 1279
            C++     L L  + +  +P      +NL  LDLS NR   +P+ + +L  L+ ++L++N L  + D ++ L ++K   CS   ++ +P+ L    +LEQ  L +N +  +P +
Sbjct:  143 CMLRNLRSLTLQQNLLENLPEEFGQLENLTELDLSKNRLTDLPQSLGRLTGLQKISLSHNKLSCLPDCLSQLTNVKLLDCSNNQLSDVPASLAHMLSLEQLHLRHNRLQRLPQL 256          
BLAST of SMED30033541 vs. Ensembl Medaka
Match: lrrc8aa (leucine rich repeat containing 8 VRAC subunit A [Source:NCBI gene;Acc:101165987])

HSP 1 Score: 62.7734 bits (151), Expect = 6.730e-10
Identity = 55/165 (33.33%), Postives = 75/165 (45.45%), Query Frame = 2
Query:  944 MTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQI--YQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAI-PHVDVHSNLKILNLSGNPIRYFKKS-FTNLKLESIGLENTWIHPLFWRKGEFS 1426
            M   T L L    +  IP+ +    NL+ +DL  N  K I E I    LH L  L L  N +  I   I  L +L+    +   I  IPS LF C+ L   DLS+NN+ +I P V    NL+ L ++ N I       F   KL ++ L N  +  L  R GE +
Sbjct:  576 MVNLTELELVRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLVCLKLWYNQIAYIPIQIGTLTNLERLYLNRNKIEKIPSQLFFCRKLRFLDLSHNNLTSIHPDVGFLQNLQYLAVTANRIETLPPELFQCKKLRTLNLGNNCLQTLPSRFGELT 740          
BLAST of SMED30033541 vs. Ensembl Medaka
Match: lrrc7 (leucine rich repeat containing 7 [Source:NCBI gene;Acc:101170832])

HSP 1 Score: 62.3882 bits (150), Expect = 9.666e-10
Identity = 43/168 (25.60%), Postives = 86/168 (51.19%), Query Frame = 2
Query:  869 GSIKQEIEDPYQEITPTKVSLMECVMTGRTHLN---LSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP-HVDVHSNLKILNLSGNPIRYFKKSFTNLK 1360
            GSI +  +  Y ++   ++  ++  ++G   L    LSS+ +  +P+ + + + L  L +  N+   +P  I  L LLE  + + N L+ +  +I  L+SL++F      +T +P  + +C+N+    L  N +  +P  +   + L++LNLS N ++    +FT LK
Sbjct:  237 GSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLK 404          

HSP 2 Score: 52.7582 bits (125), Expect = 8.596e-7
Identity = 34/104 (32.69%), Postives = 50/104 (48.08%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            L L  + +  +P  +     L  LDL  N F  +PE + Q+H L+ L L NN LQ I  SI  L  L+    +   I ++ S +  C+ LE   LS N +  +P
Sbjct:  179 LELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLP 282          

HSP 3 Score: 52.373 bits (124), Expect = 1.180e-6
Identity = 34/104 (32.69%), Postives = 54/104 (51.92%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            L L ++S+  IP  +   + LR LDL+ NR + +   +     LE L L++N LQ + DSI  L  L +       +TS+P  + S   LE+ D S N + ++P
Sbjct:  225 LWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLP 328          
BLAST of SMED30033541 vs. Planmine SMEST
Match: SMESG000061837.1 (SMESG000061837.1)

HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0
Identity = 407/407 (100.00%), Postives = 407/407 (100.00%), Query Frame = 2
Query:  359 MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPXXXXXXXXXXXXXXXXSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSLDEFEYSWAFCDLCDQIISDRSINYISFTKKFNHILPILMSFCSTLCRDSL 1579
            MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPKYEIILYENEELLKLKSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSLDEFEYSWAFCDLCDQIISDRSINYISFTKKFNHILPILMSFCSTLCRDSL
Sbjct:    1 MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPKYEIILYENEELLKLKSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLKLESIGLENTWIHPLFWRKGEFSLDEFEYSWAFCDLCDQIISDRSINYISFTKKFNHILPILMSFCSTLCRDSL 407          
BLAST of SMED30033541 vs. Planmine SMEST
Match: SMESG000061837.1 (SMESG000061837.1)

HSP 1 Score: 583.948 bits (1504), Expect = 0.000e+0
Identity = 310/310 (100.00%), Postives = 310/310 (100.00%), Query Frame = 2
Query:  359 MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPXXXXXXXXXXXXXXXXSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH 1288
            MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPKYEIILYENEELLKLKSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH
Sbjct:    1 MKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEFVKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVPYKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPKYEIILYENEELLKLKSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEITPTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVH 310          
BLAST of SMED30033541 vs. Planmine SMEST
Match: SMESG000002900.1 (SMESG000002900.1)

HSP 1 Score: 63.929 bits (154), Expect = 1.628e-10
Identity = 47/143 (32.87%), Postives = 78/143 (54.55%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPS--GLFSCKNLEQADLSYNNINAIPHVDVH-SNLKILNLSGNPIRYFKKSFTNL-KLESIGL 1378
            L L  +S++A+P+ +   + LRILD+ +N+   IP+ +++LH L  L L  N ++ +D  I NL  L++       I  +PS  GL    NL+  D+S+N++  +P    H + L  LNL  N ++   ++  NL  LE  GL
Sbjct:  155 LMLQENSLTALPDSLSQCRLLRILDIRHNKLCEIPQFVFKLHNLTHLLLRFNRIREVDPEIANLEKLQNLTLRENKIRLLPSNPGLEKLVNLQTFDISHNHLEMLPEAIGHCTKLTTLNLQHNELKLIPETIGNLTALERFGL 297          

HSP 2 Score: 61.2326 bits (147), Expect = 1.056e-9
Identity = 35/107 (32.71%), Postives = 62/107 (57.94%), Query Frame = 2
Query:  959 HLNLSSHSISAIPN--FVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            +L L  + I  +P+   +E   NL+  D+S+N  +++PE I     L +LNL +N L++I ++I NL +L+ F   +  +TS+P  L  C+ L + +   NNI+ +P
Sbjct:  223 NLTLRENKIRLLPSNPGLEKLVNLQTFDISHNHLEMLPEAIGHCTKLTTLNLQHNELKLIPETIGNLTALERFGLRYNHLTSLPGSLSCCRMLCELNTEGNNISQLP 329          

HSP 3 Score: 50.8322 bits (120), Expect = 1.924e-6
Identity = 29/104 (27.88%), Postives = 56/104 (53.85%), Query Frame = 2
Query:  962 LNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIP 1273
            LNL ++ ++ +P+ +E   NL +L LS N+FK +P  + +L  L  L+L  N L+ +   I  L  L+        +T +P  + + +NL    +  N+++++P
Sbjct:  413 LNLGTNQLAKVPDDIEYLINLEVLILSNNQFKRLPPTVKKLQKLRILDLEENLLEFLPPDIGCLQELQKLTVQSNRLTELPVSIGNLRNLTYLAVGENDLHSLP 516          
BLAST of SMED30033541 vs. Planmine SMEST
Match: SMESG000044606.1 (SMESG000044606.1)

HSP 1 Score: 61.2326 bits (147), Expect = 4.341e-10
Identity = 53/155 (34.19%), Postives = 76/155 (49.03%), Query Frame = 2
Query:  941 VMTGRT-HLNLSSHSISAIPNFVEV--FQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSN---LKILNLSGNPIRYFKKSFTNLK-LESIGLEN 1384
            V  G+T H+   +  +  IP+  ++    NLR L  S+N+ + +PE I  L  LE LNL NN +++ID  I  L SLK        ++S+P G  +   LE  DLSYNN+      D   N   L+ L LS N   Y       L+ LE + L +
Sbjct:   15 VKDGKTVHIEAINKDLYEIPDLQDLGSLSNLRSLTFSHNKIEEVPENIVLLTNLEHLNLFNNYVELIDPKINLLMSLKCLNLGMNRLSSLPRGFGAFPCLEILDLSYNNLTEKMLPDNFFNLVTLRALYLSDNDFEYLPSGIGKLENLEILALRD 169          

HSP 2 Score: 55.0694 bits (131), Expect = 3.924e-8
Identity = 47/163 (28.83%), Postives = 80/163 (49.08%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPL--QIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGNPIRYFKKSFTNLKLES----IGLE-NTWIHPL 1402
             ++T   HLNL ++ +  I   + +  +L+ L+L  NR   +P        LE L+L+ N L  +++ D+  NL +L++   S      +PSG+   +NLE   L  N++  +P+ +   S LK L+L GN +        NL L      + LE N W+ P+
Sbjct:   63 VLLTNLEHLNLFNNYVELIDPKINLLMSLKCLNLGMNRLSSLPRGFGAFPCLEILDLSYNNLTEKMLPDNFFNLVTLRALYLSDNDFEYLPSGIGKLENLEILALRDNDLLRLPNEIGKLSRLKELHLQGNRLSVLPPELGNLDLTDSKHVMKLEQNPWVTPI 225          
BLAST of SMED30033541 vs. Planmine SMEST
Match: SMESG000044606.1 (SMESG000044606.1)

HSP 1 Score: 59.3066 bits (142), Expect = 7.888e-10
Identity = 56/169 (33.14%), Postives = 81/169 (47.93%), Query Frame = 2
Query:  941 VMTGRT-HLNLSSHSISAIPNFVEV--FQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPHVDVHSN---LKILNLSGNPIRYFKKSFTNLK-LESIGLENTWIHPLFWRKGEFS 1426
            V  G+T H+   +  +  IP+  ++    NLR L  S+N+ + +PE I  L  LE LNL NN +++ID  I  L SLK        ++S+P G  +   LE  DLSYNN+      D   N   L+ L LS N   Y       L+ LE + L +  +  L    G+ S
Sbjct:   15 VKDGKTVHIEAINKDLYEIPDLQDLGSLSNLRSLTFSHNKIEEVPENIVLLTNLEHLNLFNNYVELIDPKINLLMSLKCLNLGMNRLSSLPRGFGAFPCLEILDLSYNNLTEKMLPDNFFNLVTLRALYLSDNDFEYLPSGIGKLENLEILALRDNDLLRLPNEIGKLS 183          

HSP 2 Score: 48.1358 bits (113), Expect = 4.308e-6
Identity = 39/131 (29.77%), Postives = 68/131 (51.91%), Query Frame = 2
Query:  938 CVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLIPEQIYQLHLLESLNLANNPL--QIIDDSITNLNSLKSFICSFTLITSIPSGLFSCKNLEQADLSYNNINAIPH-VDVHSNLKILNLSGN 1321
             ++T   HLNL ++ +  I   + +  +L+ L+L  NR   +P        LE L+L+ N L  +++ D+  NL +L++   S      +PSG+   +NLE   L  N++  +P+ +   S LK L+L GN
Sbjct:   63 VLLTNLEHLNLFNNYVELIDPKINLLMSLKCLNLGMNRLSSLPRGFGAFPCLEILDLSYNNLTEKMLPDNFFNLVTLRALYLSDNDFEYLPSGIGKLENLEILALRDNDLLRLPNEIGKLSRLKELHLQGN 193          
The following BLAST results are available for this feature:
BLAST of SMED30033541 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LRRC633.359e-2335.33leucine rich repeat containing 63 [Source:HGNC Sym... [more]
LRRC634.124e-2335.33leucine rich repeat containing 63 [Source:HGNC Sym... [more]
LRRC634.124e-2335.33leucine rich repeat containing 63 [Source:HGNC Sym... [more]
LRRC8D8.295e-1132.73leucine rich repeat containing 8 VRAC subunit D [S... [more]
LRRC8D8.295e-1132.73leucine rich repeat containing 8 VRAC subunit D [S... [more]
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BLAST of SMED30033541 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
let-4132.358e-1128.26pep chromosome:WBcel235:V:7972924:7977774:-1 gene:... [more]
let-4132.378e-1128.26pep chromosome:WBcel235:V:7972934:7977774:-1 gene:... [more]
fli-13.710e-1140.15pep chromosome:WBcel235:III:8675297:8683732:-1 gen... [more]
ZK546.22.080e-1029.53pep chromosome:WBcel235:II:4947036:4948070:1 gene:... [more]
ZK546.22.080e-1029.53pep chromosome:WBcel235:II:4946573:4948070:1 gene:... [more]
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BLAST of SMED30033541 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scrib1.607e-924.02gene:FBgn0263289 transcript:FBtr0308632[more]
scrib1.632e-924.02gene:FBgn0263289 transcript:FBtr0308623[more]
scrib1.833e-924.02gene:FBgn0263289 transcript:FBtr0335522[more]
scrib1.863e-924.02gene:FBgn0263289 transcript:FBtr0308620[more]
scrib1.863e-924.02gene:FBgn0263289 transcript:FBtr0308621[more]
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BLAST of SMED30033541 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CABZ01080587.19.641e-1132.79leucine-rich repeat-containing protein 30-like [So... [more]
lrrc573.477e-1034.62leucine rich repeat containing 57 [Source:NCBI gen... [more]
lrrc573.769e-1034.62leucine rich repeat containing 57 [Source:NCBI gen... [more]
lrrc18.933e-1030.46leucine rich repeat containing 1 [Source:ZFIN;Acc:... [more]
lrrc18a1.553e-927.07leucine rich repeat containing 18a [Source:ZFIN;Ac... [more]
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BLAST of SMED30033541 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000041368.15.455e-2228.69leucine rich repeat containing 63 [Source:NCBI gen... [more]
ENSXETT00000053046.18.077e-1134.96uncharacterized loc100170560 [Source:NCBI gene;Acc... [more]
LRRC21.011e-1031.76leucine rich repeat containing 2 [Source:NCBI gene... [more]
irx34.774e-1036.29iroquois homeobox 3 [Source:Xenbase;Acc:XB-GENE-48... [more]
pparg8.642e-1030.52peroxisome proliferator activated receptor gamma [... [more]
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BLAST of SMED30033541 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lrrc631.103e-1734.55leucine rich repeat containing 63 [Source:MGI Symb... [more]
Lrrc691.921e-1130.49leucine rich repeat containing 69 [Source:MGI Symb... [more]
Lrrc691.921e-1130.49leucine rich repeat containing 69 [Source:MGI Symb... [more]
Lrrd12.893e-1127.39leucine rich repeats and death domain containing 1... [more]
Lrrc8d1.035e-1033.12leucine rich repeat containing 8D [Source:MGI Symb... [more]
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BLAST of SMED30033541 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q05C16|LRC63_HUMAN1.915e-2235.33Leucine-rich repeat-containing protein 63 OS=Homo ... [more]
sp|Q4V8G0|LRC63_RAT3.680e-2034.55Leucine-rich repeat-containing protein 63 OS=Rattu... [more]
sp|A6H694|LRC63_MOUSE7.705e-1734.55Leucine-rich repeat-containing protein 63 OS=Mus m... [more]
sp|A8JAM0|DRC7_CHLRE2.633e-1330.34Dynein regulatory complex subunit 7 (Fragment) OS=... [more]
sp|B0W6M9|SUR8_CULQU3.951e-1127.27Leucine-rich repeat protein soc-2 homolog OS=Culex... [more]
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BLAST of SMED30033541 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W5MWW01.070e-2526.88Uncharacterized protein OS=Lepisosteus oculatus OX... [more]
R7UUV91.592e-2527.52Uncharacterized protein OS=Capitella teleta OX=283... [more]
V3ZNH69.763e-2528.00Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A2B4SB993.295e-2429.60Leucine-rich repeat-containing protein 63 OS=Stylo... [more]
A0A267EK013.637e-2435.80Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of SMED30033541 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000013227.21.637e-1833.73pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
lrrc572.851e-1133.93leucine rich repeat containing 57 [Source:NCBI gen... [more]
lrrc575.957e-1133.93leucine rich repeat containing 57 [Source:NCBI gen... [more]
lrrc11.556e-1029.14leucine rich repeat containing 1 [Source:NCBI gene... [more]
lrrc12.664e-1029.14leucine rich repeat containing 1 [Source:NCBI gene... [more]
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BLAST of SMED30033541 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009498.16.402e-2232.26pep scaffold:Pmarinus_7.0:GL479116:164966:178398:1... [more]
PIDD11.681e-1135.04p53-induced death domain protein 1 [Source:HGNC Sy... [more]
lrsam11.507e-927.27leucine rich repeat and sterile alpha motif contai... [more]
lrrc402.633e-927.27leucine rich repeat containing 40 [Source:NCBI gen... [more]
scrib8.321e-927.92scribble planar cell polarity protein [Source:NCBI... [more]
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BLAST of SMED30033541 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
CYR11.787e-628.57Adenylate cyclase; required for cAMP production an... [more]
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BLAST of SMED30033541 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO393453.628e-2535.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482174.939e-1132.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343456.631e-930.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371022.290e-828.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO339644.316e-831.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30033541 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc16.170e-1130.46leucine rich repeat containing 1 [Source:NCBI gene... [more]
lrrc8ab4.291e-1033.33volume-regulated anion channel subunit LRRC8A [Sou... [more]
lrrc405.902e-1029.50leucine rich repeat containing 40 [Source:NCBI gen... [more]
lrrc8aa6.730e-1033.33leucine rich repeat containing 8 VRAC subunit A [S... [more]
lrrc79.666e-1025.60leucine rich repeat containing 7 [Source:NCBI gene... [more]
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BLAST of SMED30033541 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000061837.10.000e+0100.00SMESG000061837.1[more]
SMESG000061837.10.000e+0100.00SMESG000061837.1[more]
SMESG000002900.11.628e-1032.87SMESG000002900.1[more]
SMESG000044606.14.341e-1034.19SMESG000044606.1[more]
SMESG000044606.17.888e-1033.14SMESG000044606.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033541 ID=SMED30033541|Name=SMED30033541|organism=Schmidtea mediterranea sexual|type=transcript|length=1631bp
GTTGGCTTAAATTTGAATAATTTATTTAATGTAATTTGAATTTATTTTTA
ATTCAATTATACAAGTTAATTGAATTTTTAAAAATTTGTTTTCAAATTCA
ATACGGAAAAATTTTTTTTTAACGAATATTATTTTATAATTTAACTTTGA
GCATTTTTCTGGCATGAACAAAAAAATTTTGTTACGGAGACCTAGATGTG
TAATCAACGACTGTTTAAATTTCGAAGATGCAATTTCTAAATCTGATACC
AGAATGACAAGTTTTAAAGACGATATTCAACCAGAAATCGATCAATTAGA
TAAAGATTATACGGATTTGTTGTCAAAAATTGAAAAAAATGAGGATGATG
ACTTTAAAATGAAGAATAATGAACAGGTTTCCAAACAAATGAAAATTAAT
GAATTTTCTATTGTTTCATTTTCTGATATCAATGAAGGATTAATACCAAT
AAAGCAAGAGTTTGTAAAAAAAGAAAAACAACAATATAAACAAATAAAAG
TGTCAAATAAGACTTCCAAGGAGTTCGAAAAGCTTGATCACTCTTCATCA
AAGGACAAAAGACTTGTCCATCAAAATATTTATGAACAGATCGAAGGTCA
GATTCCAGTGCCATACAAGTCAATTCCGAAGCACATTATTATAATTCAGC
TTGCAGCTCTCTTGAAATATCAACTTTCGAATGATTCTAATAAGATAGTC
AGTTGCACTGTGAAAAGTCTTGCTAGAAAAGGAAGGTTCCCTCAGTCATC
CAATCCCAAATATGAAATAATTCTGTACGAAAATGAGGAACTTCTAAAGT
TGAAATCAATTACTCCCAATAAAATTTCAGATATTCTACAAAAAGACTTA
ATGAACGCCAGCGCCGGGGGAAGTATCAAACAGGAAATCGAAGATCCTTA
CCAAGAAATAACTCCAACCAAAGTGTCATTGATGGAGTGCGTGATGACTG
GAAGAACACATCTCAATCTTTCATCTCATTCAATATCTGCTATTCCAAAT
TTTGTTGAGGTCTTTCAAAATCTTAGAATTTTGGATTTGTCTTACAATAG
GTTTAAGTTAATTCCGGAGCAAATTTATCAGCTTCACCTTCTGGAATCCC
TCAATTTAGCAAACAATCCTCTGCAAATAATAGACGATTCTATTACAAAC
TTGAATTCTTTGAAAAGTTTTATTTGCAGCTTCACACTAATCACAAGCAT
TCCTTCGGGTCTGTTCAGTTGTAAAAATCTCGAACAAGCTGATTTGTCGT
ATAACAACATCAACGCAATCCCACATGTGGACGTCCATAGTAATTTAAAA
ATTCTCAATCTCTCCGGCAATCCGATCCGATATTTTAAGAAATCATTCAC
GAATTTGAAGCTGGAAAGTATAGGACTAGAGAATACATGGATTCATCCTT
TGTTCTGGAGGAAAGGAGAGTTTTCTTTGGATGAATTTGAATATTCATGG
GCATTTTGTGATTTGTGCGATCAAATTATAAGTGACAGATCAATTAATTA
TATTTCCTTCACTAAAAAATTCAATCACATTCTTCCAATACTAATGTCGT
TTTGTAGTACTTTATGTCGAGATTCTCTTTGACATTTATCCTGCTGATTA
ATCCATCAATTTCTAGAAAATTTATATTTAA
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protein sequence of SMED30033541-orf-1

>SMED30033541-orf-1 ID=SMED30033541-orf-1|Name=SMED30033541-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=473bp
MNKKILLRRPRCVINDCLNFEDAISKSDTRMTSFKDDIQPEIDQLDKDYT
DLLSKIEKNEDDDFKMKNNEQVSKQMKINEFSIVSFSDINEGLIPIKQEF
VKKEKQQYKQIKVSNKTSKEFEKLDHSSSKDKRLVHQNIYEQIEGQIPVP
YKSIPKHIIIIQLAALLKYQLSNDSNKIVSCTVKSLARKGRFPQSSNPKY
EIILYENEELLKLKSITPNKISDILQKDLMNASAGGSIKQEIEDPYQEIT
PTKVSLMECVMTGRTHLNLSSHSISAIPNFVEVFQNLRILDLSYNRFKLI
PEQIYQLHLLESLNLANNPLQIIDDSITNLNSLKSFICSFTLITSIPSGL
FSCKNLEQADLSYNNINAIPHVDVHSNLKILNLSGNPIRYFKKSFTNLKL
ESIGLENTWIHPLFWRKGEFSLDEFEYSWAFCDLCDQIISDRSINYISFT
KKFNHILPILMSFCSTLCRDSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR003591Leu-rich_rpt_typical-subtyp
IPR001611Leu-rich_rpt
IPR032675LRR_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005886plasma membrane
GO:0043005neuron projection
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
GO:0010976positive regulation of neuron projection development
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003591Leucine-rich repeat, typical subtypeSMARTSM00369LRR_typ_2coord: 311..332
e-value: 320.0
score: 0.9
coord: 242..264
e-value: 41.0
score: 8.2
coord: 219..241
e-value: 16.0
score: 11.6
coord: 265..288
e-value: 49.0
score: 7.6
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 152..364
e-value: 1.7E-31
score: 110.9
IPR001611Leucine-rich repeatPFAMPF00560LRR_1coord: 312..332
e-value: 0.35
score: 11.6
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 201..255
e-value: 1.5E-6
score: 27.9
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 312..334
score: 6.734
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 221..242
score: 7.373
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 244..265
score: 6.449
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 290..311
score: 6.765
NoneNo IPR availablePANTHERPTHR16083:SF18coord: 196..334
NoneNo IPR availablePANTHERPTHR16083LEUCINE RICH REPEAT CONTAINING PROTEINcoord: 196..334
NoneNo IPR availableSUPERFAMILYSSF52058L domain-likecoord: 194..348