ATP-dependent (S)-NAD(P)H-hydrate dehydratase

Overview


Name	ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Smed ID	SMED30033456
Length (bp)	729

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ATP-dependent (S)-NAD(P)H-hydrate dehydratase (SMED30033456) t-SNE clustered cells

Violin plots show distribution of expression levels for ATP-dependent (S)-NAD(P)H-hydrate dehydratase (SMED30033456) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ATP-dependent (S)-NAD(P)H-hydrate dehydratase (SMED30033456) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ATP-dependent (S)-NAD(P)H-hydrate dehydratase (SMED30033456) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30033456

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30033456	h1SMcG0012327	Contig42624	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30033456	h1SMcG0012327	Contig42624	newmark_ests	PMID:29674431 Fincher et al., 2018
nervous system	SMED30033456	h1SMcG0012327	dd_Smed_v4_3409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30033456	h1SMcG0012327	dd_Smed_v4_3409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30033456	h1SMcG0012327	dd_Smed_v4_3409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30033456	h1SMcG0012327	dd_Smed_v4_3409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30033456	h1SMcG0012327	Contig32881	newmark_ests	PMID:29674431 Fincher et al., 2018
Category 3 cell	SMED30033456	h1SMcG0012327	dd_Smed_v6_3409_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Match: TPD52L2 (TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007])

HSP 1 Score: 55.8398 bits (133), Expect = 3.911e-9
Identity = 31/102 (30.39%), Postives = 52/102 (50.98%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI TLRQVL  K R    L+R +G++ + ELK + +   + ++ S  +K T   L  A   T + L+T G+ IS K   ++ +  +K    +V  +   +
Sbjct:   34 EEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRNSATFKSFEDRVGTIKSKV 135

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Match: TPD52L2 (TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007])

HSP 1 Score: 55.0694 bits (131), Expect = 8.174e-9
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            E EI TLRQVL  K R    L+R +G++ + ELK + +   + ++ S  +K T   L  A   T + L+T G+ IS K   ++ +  +K    +V  +
Sbjct:   57 EEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRNSATFKSFEDRVGTI 154

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Match: TPD52 (tumor protein D52 [Source:HGNC Symbol;Acc:HGNC:12005])

HSP 1 Score: 50.0618 bits (118), Expect = 4.655e-7
Identity = 28/102 (27.45%), Postives = 52/102 (50.98%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    ++R +GI  + ELK +   G   + ++  +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   47 EEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 148

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Match: TPD52L2 (TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007])

HSP 1 Score: 50.447 bits (119), Expect = 4.971e-7
Identity = 29/78 (37.18%), Postives = 43/78 (55.13%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEK 418
            E EI TLRQVL  K R    L+R +G++ + ELK + +   + ++ S  +K T   L  A   T + L+T G+ IS K
Sbjct:   57 EEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRK 134

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Match: AC036214.3 (novel protein, TPD52-MRPS28 readthrough)

HSP 1 Score: 51.2174 bits (121), Expect = 4.988e-7
Identity = 30/103 (29.13%), Postives = 53/103 (51.46%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            E EI+TL QVL  K +    ++R +GI  + ELK +   G   + ++  +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+  S K
Sbjct:   87 EEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKGSPK 189

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Celegans
Match: F13E6.1 (pep chromosome:WBcel235:X:10675706:10677109:-1 gene:WBGene00008745.1 transcript:F13E6.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13E6.1)

HSP 1 Score: 57.7658 bits (138), Expect = 4.210e-10
Identity = 34/111 (30.63%), Postives = 59/111 (53.15%), Query Frame = 2

Query:  161 LILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            L  +L +TE EI TL+QVL  + + A  L+R +G+TP  EL  D N  L  +  +D ++ T  V         +T +T    + EKW+ ++ ++ +K   SK+ +  ++ K
Sbjct:   64 LRTELDKTEEEISTLKQVLSARQKHAAELKRKLGLTPFSELSQDINRSLKTVTDTDAYQKTAEV-------AAATSDT----VKEKWNDMRNSSLFKSFESKLGSALNNAK 163

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Match: CG5174 (gene:FBgn0034345 transcript:FBtr0086687)

HSP 1 Score: 63.929 bits (154), Expect = 2.925e-12
Identity = 42/142 (29.58%), Postives = 71/142 (50.00%), Query Frame = 2

Query:   83 NESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            N   +  +  E A     ++E  + +   +L   E EI TLR VL  K R A  L+R +GIT   E+ DD N GL  +K S  ++ T +VL++    T S   +  + IS K   +K +   + + + V + ++++K  +TS
Sbjct:   17 NSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKTKVTS 158

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Match: CG5174 (gene:FBgn0034345 transcript:FBtr0301149)

HSP 1 Score: 63.929 bits (154), Expect = 3.443e-12
Identity = 42/142 (29.58%), Postives = 71/142 (50.00%), Query Frame = 2

Query:   83 NESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            N   +  +  E A     ++E  + +   +L   E EI TLR VL  K R A  L+R +GIT   E+ DD N GL  +K S  ++ T +VL++    T S   +  + IS K   +K +   + + + V + ++++K  +TS
Sbjct:   31 NSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKTKVTS 172

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Match: CG5174 (gene:FBgn0034345 transcript:FBtr0086689)

HSP 1 Score: 61.6178 bits (148), Expect = 1.554e-11
Identity = 41/140 (29.29%), Postives = 69/140 (49.29%), Query Frame = 2

Query:   74 SNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            S  N   +  +  E A     ++E  + +   +L   E EI TLR VL  K R A  L+R +GIT   E+ DD N GL  +K S  ++ T +VL++    T S   +  + IS K   +K +   + + + V + ++++K
Sbjct:   14 SPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVK 153

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Match: CG5174 (gene:FBgn0034345 transcript:FBtr0301148)

HSP 1 Score: 54.6842 bits (130), Expect = 8.756e-9
Identity = 47/165 (28.48%), Postives = 74/165 (44.85%), Query Frame = 2

Query:   74 SNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKST-------TTVLQNAKLI--TQSTLNTAGNK-----------ISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            S  N   +  +  E A     ++E  + +   +L   E EI TLR VL  K R A  L+R +GIT   E+ DD N GL  +K S  ++S        T  +  A L   T+S L + G K           IS K   +K +   + + + V + ++++K  +TS
Sbjct:   15 SPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKTKVTS 179

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Match: CG5174 (gene:FBgn0034345 transcript:FBtr0086686)

HSP 1 Score: 54.299 bits (129), Expect = 9.729e-9
Identity = 47/165 (28.48%), Postives = 74/165 (44.85%), Query Frame = 2

Query:   74 SNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKST-------TTVLQNAKLI--TQSTLNTAGNK-----------ISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            S  N   +  +  E A     ++E  + +   +L   E EI TLR VL  K R A  L+R +GIT   E+ DD N GL  +K S  ++S        T  +  A L   T+S L + G K           IS K   +K +   + + + V + ++++K  +TS
Sbjct:   14 SPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKTKVTS 178

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Match: tpd52l2b (tpd52 like 2b [Source:ZFIN;Acc:ZDB-GENE-030131-822])

HSP 1 Score: 63.1586 bits (152), Expect = 6.686e-12
Identity = 34/98 (34.69%), Postives = 52/98 (53.06%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            E EI TLRQVL  K R A  L+R +G++P+ E K +       +++S+ +K T   L  A   T + L+T G  IS K   ++ +  +K    KV N+
Sbjct:   59 EEEINTLRQVLSAKERHASELKRKLGLSPLTEFKQNITKSWQDVQTSNAYKKTQETLSQAGQKTSAALSTVGTAISRKLGDMRNSPTFKSFEDKVGNI 156

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Match: tpd52 (tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503-680])

HSP 1 Score: 58.9214 bits (141), Expect = 2.568e-10
Identity = 36/143 (25.17%), Postives = 72/143 (50.35%), Query Frame = 2

Query:   68 LESNNNESKTLRMVDEIAKEVTNDE---------EPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKV 469
            +E N+  ++    + E+ +E  +           E ++ +L  +L++ E EI+TL QVL  K +    ++R +GITP++ELK + + G + + +S  +K T+  L        +  ++ G  I+ K + ++ T  +K    KV
Sbjct:    1 MEENDKGTQRPDFIQEVGEEAVDAAPCSPCTVLTEQEQAELHSELQKVEEEIQTLSQVLAAKEKQVAEIKRKLGITPLNELKQNLSKGWHDVTTSTAYKKTSETLSQVGQKATTAFSSVGTAITRKLEDVRNTPSFKSFEEKV 143

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Match: tpd52 (tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503-680])

HSP 1 Score: 58.5362 bits (140), Expect = 3.800e-10
Identity = 32/109 (29.36%), Postives = 60/109 (55.05%), Query Frame = 2

Query:  143 EPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKV 469
            E ++ +L  +L++ E EI+TL QVL  K +    ++R +GITP++ELK + + G + + +S  +K T+  L        +  ++ G  I+ K + ++ T  +K    KV
Sbjct:   36 EQEQAELHSELQKVEEEIQTLSQVLAAKEKQVAEIKRKLGITPLNELKQNLSKGWHDVTTSTAYKKTSETLSQVGQKATTAFSSVGTAITRKLEDVRNTPSFKSFEEKV 144

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Match: tpd52l2a (tpd52 like 2a [Source:ZFIN;Acc:ZDB-GENE-030131-7047])

HSP 1 Score: 58.151 bits (139), Expect = 4.171e-10
Identity = 36/118 (30.51%), Postives = 57/118 (48.31%), Query Frame = 2

Query:  173 LKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYG----------------LNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            L + E+EIETLRQVL  K R A  L+  +GI+P+ E+K +   G                L  I  SD +K T   L  A  +T +  ++ G+ I  ++  ++ +  +K    KV N+
Sbjct:   36 LIKVEDEIETLRQVLVAKERHAAELKHRLGISPLSEIKQNITKGWHDVQCSNAYLTASATLEDIGRSDAYKRTQETLSQAGQVTSAAFSSMGSAIRSRFGEMRNSPSFKSFEDKVENM 153

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Match: tpd52l2b (tpd52 like 2b [Source:ZFIN;Acc:ZDB-GENE-030131-822])

HSP 1 Score: 55.4546 bits (132), Expect = 4.012e-9
Identity = 30/78 (38.46%), Postives = 43/78 (55.13%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEK 418
            E EI TLRQVL  K R A  L+R +G++P+ E K +       +++S+ +K T   L  A   T + L+T G  IS K
Sbjct:   59 EEEINTLRQVLSAKERHASELKRKLGLSPLTEFKQNITKSWQDVQTSNAYKKTQETLSQAGQKTSAALSTVGTAISRK 136

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
Match: tpd52 (tumor protein D52 [Source:NCBI gene;Acc:100135218])

HSP 1 Score: 52.373 bits (124), Expect = 5.972e-8
Identity = 28/95 (29.47%), Postives = 54/95 (56.84%), Query Frame = 2

Query:  194 IETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            I+TL QVL  K +    ++R +G+T + ELK + + GL+ + S+  +K T+  L +A     +  ++ G+ I++K + +K +  YK    +V N+
Sbjct:   44 IQTLSQVLAAKEKHHADIKRKLGVTALSELKQNISKGLHDVASTTVYKRTSETLSHAGQKASAAFSSVGSVITKKLEDVKNSPTYKSFEERVENL 138

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
Match: tpd52 (tumor protein D52 [Source:NCBI gene;Acc:100135218])

HSP 1 Score: 52.373 bits (124), Expect = 5.987e-8
Identity = 28/95 (29.47%), Postives = 54/95 (56.84%), Query Frame = 2

Query:  194 IETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            I+TL QVL  K +    ++R +G+T + ELK + + GL+ + S+  +K T+  L +A     +  ++ G+ I++K + +K +  YK    +V N+
Sbjct:   47 IQTLSQVLAAKEKHHADIKRKLGVTALSELKQNISKGLHDVASTTVYKRTSETLSHAGQKASAAFSSVGSVITKKLEDVKNSPTYKSFEERVENL 141

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
Match: tpd52 (tumor protein D52 [Source:NCBI gene;Acc:100135218])

HSP 1 Score: 51.9878 bits (123), Expect = 1.287e-7
Identity = 28/95 (29.47%), Postives = 54/95 (56.84%), Query Frame = 2

Query:  194 IETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            I+TL QVL  K +    ++R +G+T + ELK + + GL+ + S+  +K T+  L +A     +  ++ G+ I++K + +K +  YK    +V N+
Sbjct:   87 IQTLSQVLAAKEKHHADIKRKLGVTALSELKQNISKGLHDVASTTVYKRTSETLSHAGQKASAAFSSVGSVITKKLEDVKNSPTYKSFEERVENL 181

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
Match: TPD52L1 (tumor protein D52 like 1 [Source:NCBI gene;Acc:100487402])

HSP 1 Score: 50.447 bits (119), Expect = 3.713e-7
Identity = 28/108 (25.93%), Postives = 57/108 (52.78%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            ENEI TLRQVL  K +    +++ +G++ ++ELK +F+   + +++   +K T   L  A L   + +   G+ I +K   ++ +  +K    +V N   +++  + S
Sbjct:   48 ENEIVTLRQVLAAKEKHLVEIKQKLGVSMMNELKQNFSRSWHDVQTHSAYKKTQETLSQAGLKATAAITNVGSAIGKKLGDMRNSPTFKSFEERVENTVTTLRAKVGS 155

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Match: Tpd52l2 (tumor protein D52-like 2 [Source:MGI Symbol;Acc:MGI:1913564])

HSP 1 Score: 54.299 bits (129), Expect = 1.105e-8
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            E EI TLRQVL  K R    L+R +G++ + ELK + +   + ++ S  +K T   L  A   T + L+T G+ IS K   ++ +  +K    +V  +
Sbjct:   57 EEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSTAYKKTQETLSQAGQKTSAALSTMGSAISRKLGDMRNSATFKSFEDRVGTI 154

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Match: Tpd52 (tumor protein D52 [Source:MGI Symbol;Acc:MGI:107749])

HSP 1 Score: 51.6026 bits (122), Expect = 7.990e-8
Identity = 28/102 (27.45%), Postives = 53/102 (51.96%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    L+R +GI+ + E K +   G   + +++ +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   24 EEEIQTLSQVLAAKEKHLAELKRKLGISSLQEFKQNIAKGWQDVTATNAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 125

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Match: Tpd52 (tumor protein D52 [Source:MGI Symbol;Acc:MGI:107749])

HSP 1 Score: 51.6026 bits (122), Expect = 8.472e-8
Identity = 28/102 (27.45%), Postives = 53/102 (51.96%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    L+R +GI+ + E K +   G   + +++ +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   44 EEEIQTLSQVLAAKEKHLAELKRKLGISSLQEFKQNIAKGWQDVTATNAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 145

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Match: Tpd52 (tumor protein D52 [Source:MGI Symbol;Acc:MGI:107749])

HSP 1 Score: 51.6026 bits (122), Expect = 9.807e-8
Identity = 28/102 (27.45%), Postives = 53/102 (51.96%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    L+R +GI+ + E K +   G   + +++ +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   47 EEEIQTLSQVLAAKEKHLAELKRKLGISSLQEFKQNIAKGWQDVTATNAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 148

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Match: Tpd52 (tumor protein D52 [Source:MGI Symbol;Acc:MGI:107749])

HSP 1 Score: 51.2174 bits (121), Expect = 2.209e-7
Identity = 28/102 (27.45%), Postives = 53/102 (51.96%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    L+R +GI+ + E K +   G   + +++ +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   86 EEEIQTLSQVLAAKEKHLAELKRKLGISSLQEFKQNIAKGWQDVTATNAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 187

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
Match: sp|P55326|YZG1_CAEEL (Uncharacterized protein F13E6.1 OS=Caenorhabditis elegans OX=6239 GN=F13E6.1 PE=3 SV=2)

HSP 1 Score: 57.7658 bits (138), Expect = 5.355e-9
Identity = 34/111 (30.63%), Postives = 59/111 (53.15%), Query Frame = 2

Query:  161 LILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            L  +L +TE EI TL+QVL  + + A  L+R +G+TP  EL  D N  L  +  +D ++ T  V         +T +T    + EKW+ ++ ++ +K   SK+ +  ++ K
Sbjct:   64 LRTELDKTEEEISTLKQVLSARQKHAAELKRKLGLTPFSELSQDINRSLKTVTDTDAYQKTAEV-------AAATSDT----VKEKWNDMRNSSLFKSFESKLGSALNNAK 163

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BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
Match: sp|Q62393|TPD52_MOUSE (Tumor protein D52 OS=Mus musculus OX=10090 GN=Tpd52 PE=1 SV=2)

HSP 1 Score: 51.2174 bits (121), Expect = 1.545e-6
Identity = 28/102 (27.45%), Postives = 53/102 (51.96%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    L+R +GI+ + E K +   G   + +++ +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   86 EEEIQTLSQVLAAKEKHLAELKRKLGISSLQEFKQNIAKGWQDVTATNAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 187

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
Match: sp|P55327|TPD52_HUMAN (Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2)

HSP 1 Score: 50.0618 bits (118), Expect = 3.965e-6
Identity = 28/102 (27.45%), Postives = 52/102 (50.98%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  K +    ++R +GI  + ELK +   G   + ++  +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   87 EEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
Match: sp|Q95212|TPD52_RABIT (Tumor protein D52 OS=Oryctolagus cuniculus OX=9986 GN=TPD52 PE=2 SV=1)

HSP 1 Score: 48.9062 bits (115), Expect = 5.709e-6
Identity = 27/102 (26.47%), Postives = 52/102 (50.98%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSI 490
            E EI+TL QVL  + +    ++R +GI  + ELK +   G   + ++  +K T+  L  A     +  ++ G+ I++K + +K +  +K    KV N+   +
Sbjct:   47 EEEIQTLSQVLAAREKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 148

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Match: Q5BYS9 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 9.617e-18
Identity = 51/117 (43.59%), Postives = 73/117 (62.39%), Query Frame = 2

Query:  152 KKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKV----SNVHDSI 490
            + Q I +LK+ E+EI+TLRQVL  K R    L+R +GITPI+ELK +   GL  +++SD +  T+ +++ AK  T + L        EKW++L+QTN YK L  KV    SNV+ SI
Sbjct:    2 RAQWIEELKQVEDEIQTLRQVLLSKFRRQQFLKRQLGITPIEELKSEVKQGLVTLRTSDAYLKTSAIVKTAKDKTSAALF-------EKWNLLRQTNAYKSLEDKVGSACSNVYMSI 111

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Match: A0A0B7ASD7 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF139041 PE=4 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.676e-17
Identity = 49/145 (33.79%), Postives = 80/145 (55.17%), Query Frame = 2

Query:   89 SKTLRMVDEIAKEVTNDEEPDKKQLIL-----KLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS 508
            S T  +   +  E   DE P++ Q  +     +L + E+EI  LRQVLG K+R A  L+R +GITP  E K DF  GL  IK+S+ ++ T++V++ A   T S +N+ G  + +K   +K++  +K    KV   + ++K  +T 
Sbjct:   22 SSTSELGGAVGTETPPDETPEEHQRRMHEMEEELLKVESEIAMLRQVLGSKVRHATELKRELGITPFQEFKHDFQQGLEHIKNSESYQKTSSVVKTATEKTSSAINSMGQAVVKKMGDIKKSQTFKSFDEKVHTTYANVKAKVTG 166

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Match: A0A4S2LIC2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007060 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.148e-17
Identity = 49/147 (33.33%), Postives = 83/147 (56.46%), Query Frame = 2

Query:  152 KKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTSXXXXXXXXXXXXXXLNAFPSNELSDDVT 592
            + Q   +LK+ E EI+TL+QVL  K R  H L+R +GIT I+EL+++ N G++ +++S+ F+ TT V++ AK  T S L+       EKW++L+QTN +K    K+   + S++  L          +     +NA    + + +VT
Sbjct:   46 RAQYAEELKQVEEEIQTLKQVLNAKYRRQHFLKRQLGITVINELREEVNKGIDNLRTSEAFQRTTAVVKTAKEKTSSVLH-------EKWNVLRQTNAFKSFEDKLGVAYSSVRGKLVRSATVSGDHSTGSATMNATTRVQPTSEVT 185

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Match: A0A0B7ARZ2 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF139044 PE=4 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 4.002e-17
Identity = 48/140 (34.29%), Postives = 78/140 (55.71%), Query Frame = 2

Query:   89 SKTLRMVDEIAKEVTNDEEPDKKQLIL-----KLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            S T  +   +  E   DE P++ Q  +     +L + E+EI  LRQVLG K+R A  L+R +GITP  E K DF  GL  IK+S+ ++ T++V++ A   T S +N+ G  + +K   +K++  +K    KV   + ++K
Sbjct:   22 SSTSELGGAVGTETPPDETPEEHQRRMHEMEEELLKVESEIAMLRQVLGSKVRHATELKRELGITPFQEFKHDFQQGLEHIKNSESYQKTSSVVKTATEKTSSAINSMGQAVVKKMGDIKKSQTFKSFDEKVHTTYANVK 161

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Match: G7YWC1 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_112396 PE=4 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 6.241e-17
Identity = 48/147 (32.65%), Postives = 83/147 (56.46%), Query Frame = 2

Query:  152 KKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTSXXXXXXXXXXXXXXLNAFPSNELSDDVT 592
            + Q   +LK+ E EI+TL+QVL  K R  H L+R +GIT ++EL+++ N G++ +++S+ F+ TT V++ AK  T S L+       EKW++L+QTN +K    K+   + S++  L          +     +NA    + + +VT
Sbjct:   46 RAQYAEELKQVEEEIQTLKQVLNAKYRRQHFLKRQLGITVMNELREEVNKGIDNLRTSEAFQRTTAVVKTAKEKTSSVLH-------EKWNVLRQTNAFKSFEDKLGVAYSSVRGKLVRSATHSGDHSTGSATMNATTRVQPTSEVT 185

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Match: tpd52l2b (TPD52 like 2 [Source:NCBI gene;Acc:103029088])

HSP 1 Score: 62.3882 bits (150), Expect = 1.187e-11
Identity = 34/98 (34.69%), Postives = 53/98 (54.08%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            E EI TLRQVL  K R A  L+R +G++P+ E K + + G   +++S+ +K T   L  A   T +   T G+ IS K   ++ +  +K    KV N+
Sbjct:   59 EEEILTLRQVLVAKERHAAELKRKLGLSPLTEFKQNISKGWQDVQTSNAYKKTQETLSQAGQKTSAAFTTMGSAISRKLGDMRNSPTFKSFEDKVGNI 156

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Match: tpd52l2a (tumor protein D54-like [Source:NCBI gene;Acc:103035134])

HSP 1 Score: 61.2326 bits (147), Expect = 3.257e-11
Identity = 41/143 (28.67%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  158 QLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYG------------------------------------LNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            ++ ++L + E+EI+TLRQVL  K R A  LRR +GI+P+ E K++ + G                                    L+ I  SD +K T   L  A  +T S L+T G+ I  ++  ++ +N +K    K+S V
Sbjct:   29 EMQIELTKVEDEIQTLRQVLTAKERHAGELRRRLGISPLAEFKNNISKGWQEVQSSNAYMKTSQTLGDLNHRVTSSNLYLTASATLDDISHSDAYKKTQETLSQAGQMTSSALSTMGSAIRNRFGEMRNSNTFKSFEDKMSKV 171

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Match: tpd52l1 (TPD52 like 1 [Source:NCBI gene;Acc:103022083])

HSP 1 Score: 60.4622 bits (145), Expect = 5.836e-11
Identity = 35/108 (32.41%), Postives = 60/108 (55.56%), Query Frame = 2

Query:  170 KLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            +L + E EI TLRQVL  K +    L++ +GITP+ EL+ + + G N +++S  +K T+  L  A   T +  +  G+ IS K+  ++ +  +K    KV +   +IK
Sbjct:   49 ELTKLEEEITTLRQVLSSKEKRHSELKQRLGITPLSELRHNLSRGWNDMQTSTAYKKTSETLSTAGQKTTAAFSNLGSAISRKFGDMRNSPSFKSFEEKVESTVTNIK 156

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Match: tpd52l2a (tumor protein D54-like [Source:NCBI gene;Acc:103035134])

HSP 1 Score: 60.077 bits (144), Expect = 9.264e-11
Identity = 36/108 (33.33%), Postives = 58/108 (53.70%), Query Frame = 2

Query:  158 QLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYG----------------LNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILK 433
            ++ ++L + E+EI+TLRQVL  K R A  LRR +GI+P+ E K++ + G                L+ I  SD +K T   L  A  +T S L+T G+ I  ++  ++
Sbjct:   29 EMQIELTKVEDEIQTLRQVLTAKERHAGELRRRLGISPLAEFKNNISKGWQEVQSSNAYLTASATLDDISHSDAYKKTQETLSQAGQMTSSALSTMGSAIRNRFGEMR 136

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Match: tpd52 (tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503-680])

HSP 1 Score: 55.8398 bits (133), Expect = 4.859e-9
Identity = 28/98 (28.57%), Postives = 52/98 (53.06%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            E EI+TL QVL  K +    ++R +GITP++EL+ + N     + +S  ++ T+  L  A     +   + G+ IS K + ++ T  +K    +V ++
Sbjct:   98 EEEIQTLSQVLASKEKQVAEIKRKLGITPLNELRQNLNKSWQEVTTSTAYRRTSETLSQAGQKATAAFTSVGSAISRKLEDVRNTPTFKSFEDRVESI 195

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Sea Lamprey
Match: tpd52 (tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503-680])

HSP 1 Score: 48.1358 bits (113), Expect = 3.275e-7
Identity = 34/117 (29.06%), Postives = 61/117 (52.14%), Query Frame = 2

Query:  155 KQLILKLKETENEIETLRQVLGVKIRLAHHL---RRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKK 496
            ++L  +L + E EI TL+QVL  K    HHL   ++ +GI  I ELK + + G   + SS  +K T+  L +A   T + +++ G+ +S     +K +  +K    +V +    +K+
Sbjct:   79 EELREELAKVEEEIATLKQVLAAK---EHHLAEIKQKLGIGTITELKANLSKGWQDVTSSSAYKKTSETLVHAGQKTTAAISSVGSVLSRTLGDVKNSPTFKSFEERVGSTVTGLKR 192

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Match: tpd52l2b (TPD52 like 2 [Source:NCBI gene;Acc:101168606])

HSP 1 Score: 63.929 bits (154), Expect = 4.397e-12
Identity = 35/87 (40.23%), Postives = 51/87 (58.62%), Query Frame = 2

Query:  158 QLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEK 418
            +L  +L + E EI TLRQVL  K R A  L+R +G+TP+DEL+ +   G   +++S+ +K T   L  A   T + L+T G  IS K
Sbjct:   52 ELRSELTKVEEEINTLRQVLSAKERHASELKRKLGLTPLDELRHNLTKGWQDVQTSNAYKKTQETLSQAGQKTSAALSTVGTAISRK 138

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Match: tpd52l2b (TPD52 like 2 [Source:NCBI gene;Acc:101168606])

HSP 1 Score: 62.7734 bits (151), Expect = 1.126e-11
Identity = 40/123 (32.52%), Postives = 60/123 (48.78%), Query Frame = 2

Query:  158 QLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYG----------------LNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNV 478
            +L  +L + E EI TLRQVL  K R A  L+R +G+TP+DEL+ +   G                L+ I  S+ +K T   L  A   T + L+T G  IS K   ++ +  +K    +V N+
Sbjct:   52 ELRSELTKVEEEINTLRQVLSAKERHASELKRKLGLTPLDELRHNLTKGWQDVQTSNAYLTASATLDDIAHSEAYKKTQETLSQAGQKTSAALSTVGTAISRKLGDMRNSPTFKSFEDRVGNL 174

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Match: tpd52l1 (TPD52 like 1 [Source:NCBI gene;Acc:101159154])

HSP 1 Score: 62.3882 bits (150), Expect = 1.638e-11
Identity = 41/137 (29.93%), Postives = 66/137 (48.18%), Query Frame = 2

Query:  185 ENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTSXXXXXXXXXXXXXXLNAF----PSNELSD 583
            E EI TL+QVL  K +    LR+ +GITP+ ELK++F+   + +++S  FK T+     A   T +  +T G+ I+ K   ++ +  +K    KV +   +IK  +                 NA     PSN L+D
Sbjct:   55 EEEIGTLKQVLSSKEKQQAELRQKLGITPLSELKNNFSRSWHDVQTSVAFKKTSETFSTAGQKTSAAFSTFGSAITRKLGDMRNSPSFKSFEEKVESTVSTIKTKVGGSGPGGNFEEVLSSAANASSQETPSNNLTD 191

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Match: tpd52 (tumor protein D52 [Source:NCBI gene;Acc:101168132])

HSP 1 Score: 59.6918 bits (143), Expect = 1.128e-10
Identity = 37/114 (32.46%), Postives = 63/114 (55.26%), Query Frame = 2

Query:  128 VTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKV 469
            +T DE   + +L  +L + E EI+TL QVL VK R    ++R +GITP++ELK + +     + +S  ++ T+  L  A L   +  +  G+ +S K++ +K    +K L  KV
Sbjct:   31 ITEDE---RLELQEELTKVEEEIQTLSQVLAVKERRLADIKRKLGITPLNELKQNISKTWQEVTTSTAYRRTSETLSQASLKATAAFSNMGSVLSRKFEDVKNAPTFKSLEEKV 141

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Match: tpd52l2b (TPD52 like 2 [Source:NCBI gene;Acc:101168606])

HSP 1 Score: 56.6102 bits (135), Expect = 1.824e-9
Identity = 34/90 (37.78%), Postives = 52/90 (57.78%), Query Frame = 2

Query:  158 QLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQN-----AKLITQSTLNTAGNKIS 412
            +L  +L + E EI TLRQVL  K R A  L+R +G+TP+DEL+ +   G   +++S+ + + +  L +     A   TQ TL+ AG K S
Sbjct:   52 ELRSELTKVEEEINTLRQVLSAKERHASELKRKLGLTPLDELRHNLTKGWQDVQTSNAYLTASATLDDIAHSEAYKKTQETLSQAGQKTS 141

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Match: SMESG000002442.1 (SMESG000002442.1)

HSP 1 Score: 353.599 bits (906), Expect = 2.795e-125
Identity = 193/202 (95.54%), Postives = 194/202 (96.04%), Query Frame = 2

Query:   26 MSNNSCYLEEKETVLESNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTSXXXXXXXXXXXXXXLNAFPSNELSDDVTKHETDTKSTVVSG 631
            MSNNSCYLEEKETVLESNNNESK LRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKL TQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS   A  AAAATQQQLNAFPSNELS DVT+HETDTKSTVVSG
Sbjct:    1 MSNNSCYLEEKETVLESNNNESKALRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLKTQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLTS-PQAAPAAAATQQQLNAFPSNELS-DVTEHETDTKSTVVSG 200

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Match: SMESG000002442.1 (SMESG000002442.1)

HSP 1 Score: 346.28 bits (887), Expect = 3.273e-122
Identity = 193/210 (91.90%), Postives = 194/210 (92.38%), Query Frame = 2

Query:   26 MSNNSCYLEEKETVLESNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK--------KHLTSXXXXXXXXXXXXXXLNAFPSNELSDDVTKHETDTKSTVVSG 631
            MSNNSCYLEEKETVLESNNNESK LRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKL TQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK        KHLTS   A  AAAATQQQLNAFPSNELS DVT+HETDTKSTVVSG
Sbjct:    1 MSNNSCYLEEKETVLESNNNESKALRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLKTQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKLSSSIKDFKHLTS-PQAAPAAAATQQQLNAFPSNELS-DVTEHETDTKSTVVSG 208

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Match: SMESG000057565.1 (SMESG000057565.1)

HSP 1 Score: 106.301 bits (264), Expect = 2.582e-28
Identity = 62/156 (39.74%), Postives = 98/156 (62.82%), Query Frame = 2

Query:   38 SCYLEEKETVLESNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIKKHLT 505
            + YLE     +  N    ++ + ++  + EV+  E  D++ L  +L +TE EI TLRQVL VK++LA  L+R +GIT I+E+K+D  +GLN IK S+ FK+T+ V++N K  T  TL++A NK S+K  +L+ T  +K +  K+ N + S+K  LT
Sbjct:    4 APYLEGDNYYMAENGKSPESEKDLNNPSNEVS--ESVDEESLREQLSKTEEEIITLRQVLNVKLKLAQDLKRQLGITAINEMKEDIIHGLNTIKESNTFKATSVVMKNVKDKTSITLSSASNKFSQKMGMLRNTTTFKSIEGKMGNAYTSVKTKLT 157

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Match: SMESG000057565.1 (SMESG000057565.1)

HSP 1 Score: 104.375 bits (259), Expect = 2.492e-27
Identity = 60/152 (39.47%), Postives = 96/152 (63.16%), Query Frame = 2

Query:   38 SCYLEEKETVLESNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            + YLE     +  N    ++ + ++  + EV+  E  D++ L  +L +TE EI TLRQVL VK++LA  L+R +GIT I+E+K+D  +GLN IK S+ FK+T+ V++N K  T  TL++A NK S+K  +L+ T  +K +  K+ N + S+K
Sbjct:    4 APYLEGDNYYMAENGKSPESEKDLNNPSNEVS--ESVDEESLREQLSKTEEEIITLRQVLNVKLKLAQDLKRQLGITAINEMKEDIIHGLNTIKESNTFKATSVVMKNVKDKTSITLSSASNKFSQKMGMLRNTTTFKSIEGKMGNAYTSVK 153

[Close]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Match: SMESG000013104.1 (SMESG000013104.1)

HSP 1 Score: 56.6102 bits (135), Expect = 7.059e-10
Identity = 36/115 (31.30%), Postives = 66/115 (57.39%), Query Frame = 2

Query:  149 DKKQLILKLKETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSSDKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSNVHDSIK 493
            D+++L   LK+ + EI  LR  L +K++    ++  +G T +DE++ DF  G+  IK S  +  T  VL +AK  T + +    + +S+K    K++N YK++ +KV ++  S+K
Sbjct:   22 DREKLEDDLKKIQEEISDLRTTLSLKLQQEAQIKSKLGYTLLDEIQTDFQTGIKNIKESTTYHKTVEVLSSAKDKTSNVVFETKDIVSKKLHEAKESNAYKEVENKVGSLVSSMK 136

The following BLAST results are available for this feature:

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Celegans
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Sea Lamprey
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Yeast
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Nematostella
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TPD52L2	3.911e-9	30.39	TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007]	[more]
TPD52L2	8.174e-9	31.63	TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007]	[more]
TPD52	4.655e-7	27.45	tumor protein D52 [Source:HGNC Symbol;Acc:HGNC:120...	[more]
TPD52L2	4.971e-7	37.18	TPD52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007]	[more]
AC036214.3	4.988e-7	29.13	novel protein, TPD52-MRPS28 readthrough	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
F13E6.1	4.210e-10	30.63	pep chromosome:WBcel235:X:10675706:10677109:-1 gen...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG5174	2.925e-12	29.58	gene:FBgn0034345 transcript:FBtr0086687	[more]
CG5174	3.443e-12	29.58	gene:FBgn0034345 transcript:FBtr0301149	[more]
CG5174	1.554e-11	29.29	gene:FBgn0034345 transcript:FBtr0086689	[more]
CG5174	8.756e-9	28.48	gene:FBgn0034345 transcript:FBtr0301148	[more]
CG5174	9.729e-9	28.48	gene:FBgn0034345 transcript:FBtr0086686	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tpd52l2b	6.686e-12	34.69	tpd52 like 2b [Source:ZFIN;Acc:ZDB-GENE-030131-822...	[more]
tpd52	2.568e-10	25.17	tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
tpd52	3.800e-10	29.36	tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
tpd52l2a	4.171e-10	30.51	tpd52 like 2a [Source:ZFIN;Acc:ZDB-GENE-030131-704...	[more]
tpd52l2b	4.012e-9	38.46	tpd52 like 2b [Source:ZFIN;Acc:ZDB-GENE-030131-822...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
tpd52	5.972e-8	29.47	tumor protein D52 [Source:NCBI gene;Acc:100135218]	[more]
tpd52	5.987e-8	29.47	tumor protein D52 [Source:NCBI gene;Acc:100135218]	[more]
tpd52	1.287e-7	29.47	tumor protein D52 [Source:NCBI gene;Acc:100135218]	[more]
TPD52L1	3.713e-7	25.93	tumor protein D52 like 1 [Source:NCBI gene;Acc:100...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tpd52l2	1.105e-8	31.63	tumor protein D52-like 2 [Source:MGI Symbol;Acc:MG...	[more]
Tpd52	7.990e-8	27.45	tumor protein D52 [Source:MGI Symbol;Acc:MGI:10774...	[more]
Tpd52	8.472e-8	27.45	tumor protein D52 [Source:MGI Symbol;Acc:MGI:10774...	[more]
Tpd52	9.807e-8	27.45	tumor protein D52 [Source:MGI Symbol;Acc:MGI:10774...	[more]
Tpd52	2.209e-7	27.45	tumor protein D52 [Source:MGI Symbol;Acc:MGI:10774...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4


Match Name	E-value	Identity	Description
sp\|P55326\|YZG1_CAEEL	5.355e-9	30.63	Uncharacterized protein F13E6.1 OS=Caenorhabditis ...	[more]
sp\|Q62393\|TPD52_MOUSE	1.545e-6	27.45	Tumor protein D52 OS=Mus musculus OX=10090 GN=Tpd5...	[more]
sp\|P55327\|TPD52_HUMAN	3.965e-6	27.45	Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52...	[more]
sp\|Q95212\|TPD52_RABIT	5.709e-6	26.47	Tumor protein D52 OS=Oryctolagus cuniculus OX=9986...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q5BYS9	9.617e-18	43.59	Uncharacterized protein OS=Schistosoma japonicum O...	[more]
A0A0B7ASD7	1.676e-17	33.79	Uncharacterized protein OS=Arion vulgaris OX=10286...	[more]
A0A4S2LIC2	2.148e-17	33.33	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A0B7ARZ2	4.002e-17	34.29	Uncharacterized protein OS=Arion vulgaris OX=10286...	[more]
G7YWC1	6.241e-17	32.65	Uncharacterized protein OS=Clonorchis sinensis OX=...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tpd52l2b	1.187e-11	34.69	TPD52 like 2 [Source:NCBI gene;Acc:103029088]	[more]
tpd52l2a	3.257e-11	28.67	tumor protein D54-like [Source:NCBI gene;Acc:10303...	[more]
tpd52l1	5.836e-11	32.41	TPD52 like 1 [Source:NCBI gene;Acc:103022083]	[more]
tpd52l2a	9.264e-11	33.33	tumor protein D54-like [Source:NCBI gene;Acc:10303...	[more]
tpd52	4.859e-9	28.57	tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tpd52	3.275e-7	29.06	tumor protein D52 [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tpd52l2b	4.397e-12	40.23	TPD52 like 2 [Source:NCBI gene;Acc:101168606]	[more]
tpd52l2b	1.126e-11	32.52	TPD52 like 2 [Source:NCBI gene;Acc:101168606]	[more]
tpd52l1	1.638e-11	29.93	TPD52 like 1 [Source:NCBI gene;Acc:101159154]	[more]
tpd52	1.128e-10	32.46	tumor protein D52 [Source:NCBI gene;Acc:101168132]	[more]
tpd52l2b	1.824e-9	37.78	TPD52 like 2 [Source:NCBI gene;Acc:101168606]	[more]

BLAST of ATP-dependent (S)-NAD(P)H-hydrate dehydratase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000002442.1	2.795e-125	95.54	SMESG000002442.1	[more]
SMESG000002442.1	3.273e-122	91.90	SMESG000002442.1	[more]
SMESG000057565.1	2.582e-28	39.74	SMESG000057565.1	[more]
SMESG000057565.1	2.492e-27	39.47	SMESG000057565.1	[more]
SMESG000013104.1	7.059e-10	31.30	SMESG000013104.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30033456 ID=SMED30033456|Name=ATP-dependent (S)-NAD(P)H-hydrate dehydratase|organism=Schmidtea mediterranea sexual|type=transcript|length=729bp
ATTGTATTAACTTGCGGATTTTTAAATGTCAAATAATTCATGTTATTTAG
AGGAAAAAGAAACTGTTTTAGAATCCAACAATAATGAAAGTAAAACTTTA
CGTATGGTTGATGAAATTGCTAAAGAAGTAACAAATGATGAAGAGCCTGA
TAAAAAACAATTGATATTAAAATTGAAAGAGACAGAAAATGAAATTGAGA
CCTTACGTCAGGTTCTTGGTGTAAAAATTAGACTTGCTCATCATCTGAGA
AGAACTATTGGCATAACACCTATAGATGAACTGAAGGATGACTTCAATTA
TGGTTTAAATTTAATAAAATCATCTGATAAATTTAAATCAACGACAACAG
TATTGCAAAATGCCAAATTGATAACTCAATCGACGTTAAATACAGCTGGT
AATAAAATTTCAGAAAAATGGGATATATTAAAACAGACAAATAAATACAA
GCAACTCACTTCAAAAGTGAGCAATGTCCATGACTCAATAAAAAAACATC
TGACATCACCACAAGCAGCACCAGCAGCAGCAGCCGCCACGCAGCAACAG
CTGAACGCATTTCCATCAAATGAATTGAGTGATGATGTCACAAAACATGA
AACTGATACAAAATCAACAGTTGTATCTGGATGATTTGAAGATGCGAGTG
AACACGAAAAAAATTTAATAAAGTTAAATTATGAATTTCTTGTTTTATTC
ACACTTAATCAATACAATATGCACAAGAT

protein sequence of SMED30033456-orf-1

>SMED30033456-orf-1 ID=SMED30033456-orf-1|Name=SMED30033456-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=203bp
MSNNSCYLEEKETVLESNNNESKTLRMVDEIAKEVTNDEEPDKKQLILKL
KETENEIETLRQVLGVKIRLAHHLRRTIGITPIDELKDDFNYGLNLIKSS
DKFKSTTTVLQNAKLITQSTLNTAGNKISEKWDILKQTNKYKQLTSKVSN
VHDSIKKHLTSPQAAPAAAAATQQQLNAFPSNELSDDVTKHETDTKSTVV
SG*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0000166	nucleotide binding
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0016829	lyase activity
GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity
GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Vocabulary: **biological process**
Term	Definition
GO:0006470	protein dephosphorylation
GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0046496	nicotinamide nucleotide metabolic process
GO:0008284	positive regulation of cell proliferation
GO:0030183	B cell differentiation

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030131	clathrin adaptor complex
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0048471	perinuclear region of cytoplasm

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000035	Category 3 cell
PLANA:0000101	muscle cell
PLANA:0002032	epidermal cell
PLANA:0003001	lateral region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR007327	TPD52

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 43..63
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 162..200
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 165..184
IPR007327	Tumour protein D52	PFAM	PF04201	TPD52	coord: 37..152 e-value: 3.8E-19 score: 68.9
IPR007327	Tumour protein D52	PANTHER	PTHR19307	TUMOR PROTEIN D52	coord: 23..169

Main menu

ATP-dependent (S)-NAD(P)H-hydrate dehydratase

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

blazegraph-runner