ATP-binding cassette subfamily C member 4

Query: 1177 MNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMD----KRNASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++EIS      ++ LP D  K   V  ++  A W++  +    L+ +SF+++  +  A++G +G+GKSS+  A+LGEL  S G +   G ++Y SQQPW+FSG++  NILF    +  ++E+ I A AL +D++++ +  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F  CI ++  +K+ +LVTHQL  LK+  +IL+L +G M+  GT+ E +  G+D  S+LK+D  E           +  +  +    +R  + ++  S +     L    +  +   NV    +  +R E        V    Y  YF  G      + + +L       YV  D WLS+W  +        N       K D  + +G+   LT++T   G+   + +F + + S + LH KM  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DFI +   V+  + +A     W  I ++ L IIF  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRA+K++   ++ F   QD +S+A+FL++++SRWFA RLD +C +F++   +   +L+  K ++    GL L+Y + L+G+ QW VRQS+EVEN M S+ER+ EY  L  E P   ++       WP  G I F NV+  Y      VLK++  +I+ +EK+GIVGRTGAGKSSLIS LFRL E P   GKI +D+   + +GL  LR  +++IPQ+PVLF GT+R NLDPFNE TD ++   LQ
Sbjct:  392 LDEISQR----NRQLPSDGKKMVHV--QDFTAFWDK-ASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEES---------EQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSE------GKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFG--SLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPP--AWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSE-PE--GKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQ 1151          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L +TI  LP K+ + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQK ++  FAHCTVLTIAHRL+TI++SD+I+V+++G + ++D P++L  ++ +S F ++VQQ G
Sbjct: 1155 LKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNK-ESLFYKMVQQLG 1277          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQV 1021
            W+KE  R      KPSL + + +  WK Y  LG+    E    + QP  + K++++    +      L     Y+T+L    ++L ++ + Y++     GMRL++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A T +L+M    + LA + VL+IL+P Q   GKL+   R    + TD RI+ ++E+I G++++KMY WE  F  +I  LR+K +         + + +A  FS S+ I+        L+G  +++  V++ V L   +R ++   F   I    +  V+  RIQ 
Sbjct:   64 WDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQT 388          

Query: 1177 MNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMD----KRNASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++EIS      ++ LP D  K   V  ++  A W++  +    L+ +SF+++  +  A++G +G+GKSS+  A+LGEL  S G +   G ++Y SQQPW+FSG++  NILF    +  ++E+ I A AL +D++++ +  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F  CI ++  +K+ +LVTHQL  LK+  +IL+L +G M+  GT+ E +  G+D  S+LK+D  E                                 S++  VP  +P +   T S  S     SSR  L+  + ++  +                             YV  D WLS+W  +        N       K D  + +G+   LT++T   G+   + +F + + S + LH KM  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DFI +   V+  + +A     W  I ++ L IIF  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRA+K++   ++ F   QD +S+A+FL++++SRWFA RLD +C +F++   +   +L+  K ++    GL L+Y + L+G+ QW VRQS+EVEN M S+ER+ EY  L  E P   ++       WP  G I F NV+  Y      VLK++  +I+ +EK+GIVGRTGAGKSSLIS LFRL E P   GKI +D+   + +GL  LR  +++IPQ+PVLF GT+R NLDPFNE TD ++   LQ
Sbjct:  392 LDEISQR----NRQLPSDGKKM--VHVQDFTAFWDK-ASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEE---------------------------------SEQPPVPG-TPTLRNRTFSESSVWSQQSSRPSLKDGALESQDVA----------------------------YVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFG--SLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPP--AWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSE-PE--GKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQ 1104          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L +TI  LP K+ + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQK ++  FAHCTVLTIAHRL+TI++SD+I+V+++G + ++D P++L  ++ +S F ++VQQ G
Sbjct: 1108 LKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNK-ESLFYKMVQQLG 1230          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQV 1021
            W+KE  R      KPSL + + +  WK Y  LG+    E    + QP  + K++++    +      L     Y+T+L    ++L ++ + Y++     GMRL++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A T +L+M    + LA + VL+IL+P Q   GKL+   R    + TD RI+ ++E+I G++++KMY WE  F  +I  LR+K +         + + +A  FS S+ I+        L+G  +++  V++ V L   +R ++   F   I    +  V+  RIQ 
Sbjct:   64 WDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQT 388          

Query: 1294 NEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQ----GVDVHSILKQDTTEYVIDKSRTTFNEDAIY-----VSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSAC---NLSSRDELEQFSHDN------------VKLNLYWKYF-TVGC-SAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKND-KPFLIGLILLTLSTFAGGLLSVICLFLIC---IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSD-FGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            +E  ++D++  + A Q  A+IG +GSGKSS+  A+LGE+    GHI   G+ +Y  QQ WI +G+I  NILF    N + ++Q + A AL  D+E++P   L  +GE+G+ LSGGQK RISLARA Y   DI LLDDPL+AVDA VG  IF + +    L K K  LLVTH +H L  VD+I+VL  G ++  G+++ ++++      ++ + L+    E        +  ED  Y     V EI ED A ++  R  +  +     S    G    ++ ++    N++S  E E+                 VK ++Y +Y   +G  S FF++L F++ +     ++ +++WLS WT++    N++D    + D +  + G + L     A G+   I  F      +++   LH+++L++IL +P++FF+    GRI+NRF+ DIS  DD LP +L+ +I     ++  L +         II++ L II+ +++  Y++ S  ++RL++VTRSP+++H S T+ GL  IRAF+ Q  F K  + + D   K  F +I+S+RW A RL+ V     +T  +S + +V ++   + D  G VL+  + +     W VR +SE+E  + ++ERI EY  +  E P +T +      DWPS G+I+F N  + Y      VL+ +   I   EKIG+VGRTGAGKSSL + LFR++E     G+II+D  DI+++GL  LR  + +IPQDP+LF G++R NLDPFN ++D ++   L+
Sbjct:  650 SEATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAKNLKTFLRHTGPEEEATVHDGSEEEDDDYGLISSVEEIPED-AASITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVKGQKLIKKEFIETGKVKFSIYLEYLQAIGLFSIFFIILAFVMNSVA---FIGSNLWLSAWTSDSKIFNSTDYPASQRDMRVGVYGALGL-----AQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGN---LTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPWVTDKRPPP--DWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAA--GGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALE 1411          

Query: 3564 LYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLF 3854
            L   V+E G NLS+GQRQL+C+ RALL+++K++V+DEATA VDL TD+LIQ T+Q+ FAHCTV+TIAHRL TIM+SD+++V++NG + +   P  L 
Sbjct: 1426 LSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELL 1522          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL 778
            Y+ L  K+G++++  I A VY+K L L+  A  + T G+ +NLMS D  K      F+H +W   L  V +   L+   RE G   LA + V++++IP    L       +   +   D+R+K+++E+++G++++K + WEP F   +  LR+K L
Sbjct:  381 YFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLW---RELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRKKEL 533          

Query: 1153 FLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK--------QDTTEYVIDKSRTTFNEDAIYVSEITE--DRATNLNN----RNSSKEQTVPLLSPVIT--GETASNVSSACNLSSRD----------ELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDF------ILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            FLS  E E + I        +P+  D    +S+T  N    W    ++   L  I+FS+      A++G++G GKSS+  ALL E+   +GH+   GS++Y  QQ WI + S+ +NILF    +   +   I A AL  D+EI+P+   T +GE+GV LSGGQK R+SLARA Y  ADI L DDPL+AVDA VG  IF   I    + K+K  +LVTH +  L  VD I+V+  G +   G++ E++++       L+        QD  E       T  +E+   V+ ++     A  + N     +S+ +Q    LS   +  G+ + + +S   L   +          E ++     VKL++YW Y       F   L   L+       + ++ WLS WT   D    +  + +   +  + G + ++      G    + +  I    C  LH  +LHSIL SP+ FF    +G ++NRFSK++   D ++P  ++ F      ++  C+V+    LA+     + III  L +I++ ++R Y+  S  +KRLE+V+RSP+++H + TL G++ IRAF+ Q  F  +   K D   KA++  I ++RW A RL+ V    ++ A  +  A++    ++    GL ++Y + +     W VR SSE+E  + ++ER+ EY     E P   +E  +    WP  GR+EF+N  L Y      VL+++N+ I   EK+GIVGRTGAGKSSL   LFR+ E     G+II+D  +I+ +GL  LR  I +IPQDPVLF G++R NLDPF++++D +V T L+
Sbjct:  293 FLSHEELEPDSIER------RPVK-DGGGTNSITVRNATFTWAR--SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEE----NGSTVMDEEEAGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMK-AIGLFISFLSIFLFMCNHVSALASNYWLSLWT---DDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRC--LHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVIL---LATP---IAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFA--ALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQE-TAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAE--GEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLE 1088          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L D ++ LPDKL    +EGG NLSVGQRQL+C+ARALL++ K++V+DEATA VDL TD LIQ T+++ F  CTVLTIAHRL+TIM+  R+IV++ G + ++  P  L   R    F  + +  G
Sbjct: 1092 LKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQR--GLFYSMAKDAG 1213          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGL 889
            Y+ +    GMR+K  +   VY K L +   A   +T G+I+NLMS D  +F     +++ IW  PL  +    +L++    + LA + V+++++P    +      ++   +   D RIK+++E++NG++V+K+Y WE  F   +  +R++ L     + L KS ++      S      ++C  FLV L
Sbjct:   58 YFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEEL-----KVLKKSAYL------SAVGTFTWVCTPFLVAL 236          

Query: 1153 FLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK--------QDTTEYVIDKSRTTFNEDAIYVSEITE--DRATNLNN----RNSSKEQTVPLLSPVIT--GETASNVSSACNLSSRD----------ELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDF------ILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            FLS  E E + I        +P+  D    +S+T  N    W    ++   L  I+FS+      A++G++G GKSS+  ALL E+   +GH+   GS++Y  QQ WI + S+ +NILF    +   +   I A AL  D+EI+P+   T +GE+GV LSGGQK R+SLARA Y  ADI L DDPL+AVDA VG  IF   I    + K+K  +LVTH +  L  VD I+V+  G +   G++ E++++       L+        QD  E       T  +E+   V+ ++     A  + N     +S+ +Q    LS   +  G+ + + +S   L   +          E ++     VKL++YW Y       F   L   L+       + ++ WLS WT   D    +  + +   +  + G + ++      G    + +  I    C  LH  +LHSIL SP+ FF    +G ++NRFSK++   D ++P  ++ F      ++  C+V+    LA+     + III  L +I++ ++R Y+  S  +KRLE+V+RSP+++H + TL G++ IRAF+ Q  F  +   K D   KA++  I ++RW A RL+ V    ++ A  +  A++    ++    GL ++Y + +     W VR SSE+E  + ++ER+ EY     E P   +E  +    WP  GR+EF+N  L Y      VL+++N+ I   EK+GIVGRTGAGKSSL   LFR+ E     G+II+D  +I+ +GL  LR  I +IPQDPVLF G++R NLDPF++++D +V T L+
Sbjct:  293 FLSHEELEPDSIER------RPVK-DGGGTNSITVRNATFTWAR--SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEE----NGSTVMDEEEAGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMK-AIGLFISFLSIFLFMCNHVSALASNYWLSLWT---DDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRC--LHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVIL---LATP---IAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFA--ALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQE-TAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAE--GEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLE 1088          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L D ++ LPDKL    +EGG NLSVGQRQL+C+ARALL++ K++V+DEATA VDL TD LIQ T+++ F  CTVLTIAHRL+TIM+  R+IV++ G + ++  P  L   R    F  + +  G
Sbjct: 1092 LKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQR--GLFYSMAKDAG 1213          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGL 889
            Y+ +    GMR+K  +   VY K L +   A   +T G+I+NLMS D  +F     +++ IW  PL  +    +L++    + LA + V+++++P    +      ++   +   D RIK+++E++NG++V+K+Y WE  F   +  +R++ L     + L KS ++      S      ++C  FLV L
Sbjct:   58 YFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEEL-----KVLKKSAYL------SAVGTFTWVCTPFLVAL 236          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKN-NQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE---LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQ---------------------------------------GVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWT--TEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            S++  EN    W+ +   +  L++ISF ++  Q  AI+G++GSGKSS+  ALLGE+    G +   G+++Y  QQ WI + S+  NILFN P +   +E  +   AL  D+  +P    T +GE+G+ LSGGQK R+SLARA Y   DIILLDDPL+AVD+ VG  IF   IS        K  +LVTH L  LK  D+++VL EG +   GT+ E+++                                        G     ILK+  +    +  +   +  AI  S  +  R+  L++  S  E+   LL     G  + +V +  N +   E E      VK  +Y  YF    S    +L F LY  +  L + ++ +L+  +   +   R +SDA+         I  +L    +F   L++ I L +  + + + LH  +L +I+ SP+ FF+    GRILNR  KDI   D  LP  ++   ++   V+  L +  +   W+ I    L +I++ + R Y++ S  +KRLE+ +RSP+++H   ++QG ++IRAF   + F K+ Q++ D +  A++  I ++RW A RL+ V  + +++A  + V       ++    GL ++Y + +     WAVR +SE+E  + S+ERI EY   PTE    ++ L ++   WP  G I  +N S+ Y      VL  ++  I   EK+GIVGRTGAGKSSL   LFR++E   D G I +D  +I+ L L++LR+ + ++PQDPVLF GT++ NLDPF+ ++DS V   L+ +
Sbjct:  612 SAIEVENGLFSWSSD--EDPTLREISFKIQKGQLVAIVGKVGSGKSSLLHALLGEMNKLSGSVQINGNIAYVPQQAWIQNMSLRNNILFNKPYDLENYEDVVKNCALKEDLANLPAGDRTEIGEKGINLSGGQKQRVSLARAVYQNPDIILLDDPLSAVDSHVGKHIFENVISSSTGCLASKTRVLVTHGLTYLKHCDQLIVLKEGTISELGTYQELLNNSGAFAEFLEEFLIEESKTRGRVASIGDGSGEVDEILRDLGQVKPGILKRLESHLSQESDKEDTSARAIEYSRDSSRRSVLLHSPRSQHEENEALL-----GAISEDVPAQEN-TQLIEKETVETGKVKFEVYIAYFQ-AISIPITLLFFFLYVGSSGLGILSNFYLAKLSDHAKSGNRTSSDAKM-----ELGIYAVLGMGQSFV-VLIASIILTIGVLRASRILHAGLLGNIMRSPMAFFDVTPIGRILNRIGKDIEAIDRTLPDVIRHMSMTIFNVVATLVVIMWATPWAGIAFAILSVIYFIVLRFYISTSRQLKRLESASRSPIYSHFQESIQGASSIRAFGVVDNFIKQSQQRVDDHLIAYYPSIVANRWLAVRLEMVGNLIVLSAAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVSVERIKEYTVTPTEGNN-SRRLAAK--SWPEKGEISIKNFSVRYRPGLDLVLHGISAHIAPSEKVGIVGRTGAGKSSLTLALFRIIE--ADGGSIEIDGINIANLQLEQLRSCLTIVPQDPVLFSGTMKMNLDPFSAYSDSQVWEALENA 1399          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQ 3893
            +  L D L   +SEGG NLSVGQRQLIC+ARALL++ KV+V+DEA A VD+ TDSLIQKT++  F  CTVLTIAHRL+T+M+SDR++V++ G V +FD P  L ++ PD  F  + +
Sbjct: 1405 VKSLQDGLEHKISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLIQKTIREQFKECTVLTIAHRLNTVMDSDRLLVLDKGRVAEFDSPKNLLAN-PDGIFYSMAK 1520          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGL 889
            YY    ++GM ++  + + VY K L L+ +A    T G I+NLMS DI K +     +   W  PL    +   L+ F   A LA ++VL++ +P    +     K +   + + DERIKM+SE++NGM+V+K+Y WE     ++ K+R + L    ++KL  S ++A        I+ +++C  FL  +
Sbjct:  357 YYHSMFRLGMHVRSVLTSAVYSKALNLSNEARKGKTIGAIVNLMSVDIQKIQDMAPTIMLFWSAPLQIFLSIYFLWKFLGVAALAGLVVLILALPVNGLIAIQMRKCQTEQMKLKDERIKMMSEILNGMKVLKLYSWERSMENMVLKIREREL--HILKKL--SYFMAA-------IVFSWICAPFLASV 535          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKC-SSVTFENVFAKWN-ENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQ-------------GVDVHSIL---KQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDEL---EQFSHDNVKLNLYWKYFTVGCSAFFVVLMFI-LYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEV--CTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            +EFL   E +   +  SV         +I++  ++V  EN+ A W+ E    E  L+D+  +       A++G++GSGKSS+  ALLGE+   +G I   G ++Y  QQPWI + ++  NI F  P    +++Q + A AL  DI+I+P    T +GE+G+ LSGGQKAR+SLARA Y   D+ LLDDPL+AVDA VG  IF + I    L ++K  +LVTH L   K  D+ILV+ EG +   GTF  +I +             G D  S     + D  E +  + +   N + + ++ +T D    L+    + E T  + +     +  +  S A    S+++L   E  +   V++  Y  Y  V  + + + + FI  +   MTL +    WLS W+ E D  + S     K  +  + G   L  S  A   ++++ L  +   + K LH  ++H+++ SP+ F++    GRILNR +KDI   D +LP+  +  ++    V F L +         ++IL L +I+    R Y+  S  +KRLE+V RSP+++H   T+QG  +IRAF   + FR++  +  D + +  +  + S+RW A RL+ V  C +F   A+++ ++  +    +    G+ ++Y + +  +  +AVRQ SE+E  + S+ER+ EY   P E P    E       WPS G ++F   S  Y      VL +++  +   EKIGIVGRTGAGKSS    LFR++E     G+I++D  ++S +GL  LR++I +IPQDPVLF GT+R NLDPF  ++D  +   L+
Sbjct:  596 KEFLVAEELDEKCVDRSV---------NIERSHNAVRVENLTASWDPEEAAGEKTLQDVDLTAPRNSLIAVVGKVGSGKSSLLQALLGEMGKLRGRIGVNGRVAYVPQQPWIQNMTLRDNITFGRPFDRKRYDQVLYACALKADIKILPAGDQTEIGEKGINLSGGQKARVSLARAVYQNLDVYLLDDPLSAVDAHVGRHIFEKVIGPNGLLREKTRILVTHGLTYTKMADEILVMLEGKIEESGTFEHLIKRRGLFFDFMEEYKSGSDNSSEAGGSQDDDFEAIGGEIQDYMNPEDVVLT-VTND----LDETIRTPELTTQISTMSSPEKPPTGTSPAAATESQNKLIKKEGIAQGKVEIATYQLY--VKAAGYLLSIAFIGFFIVYMTLQILRSFWLSAWSDEYDPDSPSAHPMAKGWRLGVYGA--LGFSETACFFVALLALVFVGQRASKNLHGPLIHNLMRSPMSFYDTTPLGRILNRCAKDIETIDMMLPMNFRYLVMCVLQVAFTLIVIIISTPLFAVVILPLALIYLIFLRYYVPTSRQLKRLESVHRSPIYSHFGETIQGAASIRAFGKVDEFRQDSGRILDTFIRCRYSSLVSNRWLAVRLEFVGNCIIFF-AALFAVLSKEFGWITSPGVIGVSVSYALNITEVLNFAVRQVSEIEANIVSVERVNEYTNTPNEAP-WRIEGREPAPGWPSRGVVKFDGYSTRYREGLDLVLHDISADVAAGEKIGIVGRTGAGKSSFALALFRMIEAA--GGRIVIDDVEVSQIGLHDLRSNITIIPQDPVLFSGTLRFNLDPFFTYSDDQIWRALE 1393          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKK 3920
            LPD L   +SE G NLSVGQRQL+ +ARALL+  +V+V+DEATA VD+ TD+LIQ+T++  F  CTV TIAHRL+TIM+ DRI+V++ G + +FD P  L +D+ +S F ++V     AE+ K
Sbjct: 1404 LPDGLLYKISEAGENLSVGQRQLVALARALLRHTRVLVLDEATAAVDVATDALIQETIREEFKECTVFTIAHRLNTIMDYDRIMVLDKGSILEFDTPDALMADK-NSAFAKMVADA--AEQDK 1523          

Query:   83 EQRRNK---PSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLL----YGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLP---LSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            EQ ++    PS++  +  +   E+     L F  + +  + PF++ +LL+F +  N    + +  S L+     L  LI N Y+++  +MG +++  + A VY+K L ++  A    T G+I+NLM+ D+ +F+     +   W  P       V L++    + L  +++++I +P  I    +  K++   + + DER KMV+E++NG++VVK+Y WE      I ++R K L        VR +  S   A     S F++  +    F++  P   L+ Q+ ++++ L NQ+R+ +    +L I  A+   V+  R++
Sbjct:  281 EQEKDPVVIPSVVSSLFMMFRWEFLLASTLKFVSDTMQFASPFLLHELLNFISAKNAPFWKGMALSILMFSVSELRSLILNGYFYIMFRMGTKIQTSLTAAVYKKTLLISNSARRDRTVGEIVNLMAIDVERFQMITPQIQQFWSCPYQITFALVYLFITLGYSALPGVVIMVIFVPMNIISSMIVRKWQIEQMKLKDERTKMVNEVLNGIKVVKLYAWEVPMEAYIDEIRTKELALIKKSAMVRNILDSFNTA-----SPFLVALFSFGTFVLSNPSHLLTPQIAFVSLALFNQLRSPMT-MIALLINQAVQAVVSNKRLK 596          

Query: 1273 KWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNS----SKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGC--SAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNA----SDAEFYKN---------------DKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKE---LDSQLID-WPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            K +E +   Y ++D+SF   A     IIG +GSGKSS+ + +L E  +++G++   GS +Y +Q+PWIF+GSI  NI+F    N + +E  +    L  D+    N  +T VG+ G  LSGGQ+AR++LARA Y  ADI LLDDPL+AVDA VG +++   I     DKLV+LVTHQ+H L  +D ++++    M+  G+ +E+ S   D    +K    E       T    D ++V         +  N  S    +KE      + V++G   S       +      E      +  ++YW+Y T G      + + + +    T  +  F D WL+ W  ++D  NA    S  EF +N               +  F+I  +++++     G++  +      + + + LH  M   +L +  +FF++NS G ILNRFSKDI + DDLL  T  +F+  T   +  +GL S      I+   F+   F+  R+ Y++ S  +KR+EA  RSPL   I++T+ GL+TIRA++ +N   ++F    D Y  A+ + + S+RWF   +D + +VF+  +I + V ++ ++ +   + GL L   V L G   W +RQS+E+EN M S+ER+ EY  L +E          LD QL++ WP+ G IEF+NVS+ Y   +  VLKN++ ++   +KIG+VGRTGAGKS+LI ++F L E     G++ +D  D+  + L   R  +++IPQ+PV+F GT+R NLDPF+E+ D+ +   L+
Sbjct:  508 KKDEPLHVVYAVQDLSFEFVAGTCYGIIGSVGSGKSSLLLTILSESRMTRGNLSVNGSFAYCAQEPWIFTGSIQDNIVFGSEFNKERYENALELCLLTPDLRQFANGDMTIVGDNGSTLSGGQRARVALARAVYADADIYLLDDPLSAVDAHVGKKLYENLIRGFLSDKLVILVTHQIHFLSELDSVILMKNNKMVGNGSLDELKSTFTD--DFIKLQAVE-------TEVQSDELFVDGPPSSPPPSPVNIESMEKINKESIFQRANSVLSGSKMSETEYVKEIV----YESRKSGTISWSVYWEY-TRGVINPLKYGIWLVVCVLITQLMNNFVDWWLNKWLVDLDMNNADNSTSKEEFNRNVDVLGYTFNVTFQTYELTFIISTVIMSIL----GVVRSVWFRNAQLMASRILHNSMFDCVLKTESEFFDKNSEGMILNRFSKDIGLTDDLLAFTYFEFVFGTLTFVGIVGLVSMVRPIVILACAFITAGFYFCRKMYVHRSRELKRIEAAARSPLNTTITSTVHGLSTIRAYRKENEMIEKFCALHDVYMAAYNMGLLSARWFGICIDFLVSVFV--SIVAIVVVLQYETLTVGEVGLCLVCAVQLSGFFSWIMRQSAELENGMVSVERVLEYTKLKSEEEARRPHDAYLDKQLLNSWPTKGEIEFENVSVNY--GETKVLKNLSFVVLGGQKIGVVGRTGAGKSTLIKIIFGLKEYC--SGRVTIDGVDLDHISLNFRRGGMSIIPQEPVIFSGTVRENLDPFDEYDDATIWFALE 1264          

Query: 3576 VSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            + + G +LSVGQRQL C+ARA++ R+K++VIDEATANVD  TD+ IQKT++  F + T++T+AHRL TIMNSD ++V   G + +FD P  L  D+  S F ++  Q+G      LR  A
Sbjct: 1282 LGQRGVSLSVGQRQLFCLARAMIHRSKILVIDEATANVDGVTDACIQKTIRDFFKNATIITVAHRLHTIMNSDNVMVFEKGELVEFDKPITLLDDQ-SSLFSRMAAQSGAENFDSLRAAA 1400          

Query:  311 RNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIR 943
             +PY+   +K+G   ++  G ++Y K L+++  +L +T SGQII L+++D  K E +  F H++W+ PL+      IL+       L   +V++ ++  Q+         R  I    D R+K++SE+ING++V+KM+ WE  F + I  LR   +          S+ + + F  ++  +  Y+         L+++ V+ +  L N +R
Sbjct:  180 HHPYFHGLLKVGNHARVATGVLLYRKSLRISLTSLFETNSGQIIQLLNTDAAKLEQAFLFAHYVWLCPLLMFFYAYILWSMFGFCCLLGFLVMMAIVSFQVHYSYQLGVNRRNIGDKMDSRLKVMSEIINGIKVIKMHGWENAFAEKIRILREDEIKAVGTSAFYSSMVMGIYFISAKIGLFVYIFACDYFDEILTTRGVFASSALFNSVR 390          

Query: 1306 LKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQF-EQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETA-SNVSSACNLSSRDELEQFSHDN----------------------------------VKLNLYWKYFTVGCSAFFVVLMFILYATTMTLY-VFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYS--------CKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSD-FGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            L +ISFS+   Q   I+G +G+GKSS+  AL+GE+    G I   G L Y  QQPW+ + ++ QNI F    +  F  + + A AL RD++I+P    T +GE+G+ LSGGQKARISLARA Y   DI LLDDP++AVDA VG Q+F   I    + ++K  +LVT++L  L+  D I+V++EG +   G +++++ QG     +++ +  E    ++  + +ED     E +E     +   +  +     + SP+I      S++S+   + +R  +   +H                                    VK++ Y+KYF  G     + ++F+L  TT T++ +  ++WL+ W+ +   R+ S+       +P     I + L  +AG   S I L  I + S         + LH  ++ ++   P+ F++    GRILNR  KDI   D LLP  +Q F      V+  L +         I+I+ L +++  + R Y+  S  +KRLE++TRSP+++H+S ++QG  TIRA+   + F K  + K D + +  +L   ++RW + RL+ +    +   ++S +     +   TS   GL ++Y + +  +  +AVRQ +++E  + S+ER+ EY    TE    ++       +WPS GRI   N S  Y      V+K +N+ I+  EK+GIVGRTGAGKSS+   LFR++E     G+I+VD  +++ +GL  LR+++ +IPQDPVLF GT+R NLDPFN ++D D+   L+ ++
Sbjct:  678 LTNISFSVNRGQLVTIVGRVGAGKSSMLQALMGEMEKLSGSISMHGRLCYVPQQPWMQNNTLRQNITFGKQFDEYFYSRVLDACALYRDLQILPLGDNTEIGEKGINLSGGQKARISLARAVYQNHDIYLLDDPMSAVDAHVGSQLFGSVIGPEGMLRNKTRILVTNELSFLEKSDLIIVMNEGKIEYSGKYDDLMQQGAFEQLLIECEKEERERREAEASADED----DENSEPGGIMIGGDSDFEYDDDVMASPIIDHVLGTSHMSTVSGIINRRRISTSTHKQRRRLSTTKSHTHSITSASTQTRQLTGTERVETGRVKMDTYYKYF--GAMGMSIAVLFVLGMTTSTIFSMGRNLWLTDWSNDNAARSGSNT----TGQP-----IAIRLGVYAGLGFSEIILLFIGMLSLLYGGVSASRNLHAPLMRNLFRVPMAFYDTTPFGRILNRIGKDIETVDVLLPFNVQFFAQCLLQVVSTLIIIMISTPVFGIVIIPLSVMYLMVMRYYIATSRQLKRLESITRSPIYSHLSESIQGSATIRAYHLVDRFCKLSETKVDSHVQCRYLNYVANRWLSVRLEFIGNCIV---LFSALFAALTRTTTTSGVIGLSVSYALNITTVLNFAVRQITKLETNIVSVERVKEYAETETEAEWKSEPGKEPPQNWPSEGRIVMNNYSARYRPGLNLVVKQLNVEIKPHEKVGIVGRTGAGKSSVTLSLFRIIEAAE--GQIVVDGINLAEIGLHDLRSNLTIIPQDPVLFSGTLRFNLDPFNHYSDGDIWKTLEMAN 1448          

Query: 3558 DKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            ++L   ++EGG N+SVGQRQL+C+ARALL++ +V+++DEATA VD+ TD+LIQKT++  FA+ TVLTIAHRL+TIM+ DRIIV+N+G V +FD P  L S+R +S F  + ++ G
Sbjct: 1458 EQLNYIITEGGDNISVGQRQLVCLARALLRKTRVLILDEATAAVDVSTDALIQKTIREEFANATVLTIAHRLNTIMDYDRIIVLNDGKVGEFDSPANLLSNR-NSEFYSMAKRAG 1571          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEP-SLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLA-KSLWVALRFSGSRFIIIAYMCCAFLVGLP---LSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            Y++L  ++G R++  + A VY K L+L+  A  + T G+I+NLM+ D+ +F+  + Q + + W  P        +L+     +  + + V+++L P    +  +  K++   +   DER KMV+E++NG++V+K+Y WEP   +VI  LR + L  G ++K A    +  +  + S F++       F+   P   L+ ++ ++++ L NQ+R+ +     L IT  + + V+  R++
Sbjct:  401 YFYLMYRVGTRVQTCLTAAVYRKTLRLSNAARREKTVGEIVNLMAIDVDRFQQITPQTMQY-WSNPFQIGLALFLLFQQLGVSVFSGVAVMVLLFPINFVITMIIRKWQIAQMYYKDERTKMVNEVLNGIKVIKLYAWEPPMEQVIEDLREQEL--GLIKKAAFLRTFSDMLNTASPFLVALSTFATFIYIDPKNVLTPEIAFVSLTLFNQLRSPMSQVAEL-ITQTVQVVVSNRRLK 634          

Query: 1453 YTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNAS---DAEFYK-----NDKP--------FLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFI--LSTCLVLFGLGLASYKNY--WSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIA-LPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLINFL 3558
            Y  Q+ WIF+G++  NILF    N++ + + +    L  D+  +     T VGERG  LSGGQKAR++LARA +   ++ L DD  A++D  V ++I  + I +L K K +++VT+ + LL   D++L +  GN++A G            H IL +    Y       TF  DA    + T    +   +      Q  PL + ++   +      A  L S DE E   +  +   +Y +Y            + I +   +   +F+  WLS W  +      +     EF +      D P        +L+ L++LT+S    GL        + + +   LH++M  +++     FF+    GRILNRFSKD+   D  LP T + F+  + TCL    +  + +  +  ++I + +  ++     R    N    +KR E ++RSPL+ H+S +L+G+TTI  F+  N F +  +K  D  S A F++ S+ RW A  LD    V ++TAI + + ++    ++ +D G+ + + V + G+ Q+AVR  +E+E +MTS+ER+  Y   +P +    T++       WP+ G+I F  V+L Y       L ++   I+  EK+GI+GRTG+GKSSL +L+FRL   P   G I +D  DI T+GL KLR  I+ I QDP LF GT+R NLDP  E++DS +   L+      L+  L
Sbjct:  551 YVPQKAWIFNGTVQDNILFGDKMNSERYYKAVNGCQLTEDLTTLSVGDRTEVGERGATLSGGQKARVALARAVFQTKNLYLFDDIFASLDKKVANKIHEEIIQKLLKKKALMMVTNNMELLHHFDRVLFVEGGNIVADGN-----------HDILYEKNDAY------KTF-VDACETYQATSGATSPCGD---GPAQPAPLDAEILRNSSEDLKGDADKLIS-DE-EDMGNSTIAWRIYKQYIHAAGGWPIWTCLVIGFIVNVVSNIFSTYWLSRWLKKGHDETTTITNGTEFLEMKTSLADSPVTGFYAAVYLVALVVLTIS----GLFKACVFVKVSLTAATRLHDRMFQAVIHGATSFFDSTPTGRILNRFSKDMDEIDVKLPFTAEVFLQNMITCLGFLVVITSVFPYFLLFAIPLFVVFVVFVSCFRAGIRN----LKRSEHISRSPLYDHVSASLEGITTIHTFQQSNRFLEVLKKHLDCNSGAIFMFQSAMRWLAVWLD--LLVVVMTAIVALLTVMLTGTVSPADAGMAIAFAVQMSGIFQFAVRTQTELEAKMTSVERVSYYADNIPEDGEWNTRQGLDIESSWPANGQINFSEVNLRYRKSHPLALNDITFEIKGGEKVGIIGRTGSGKSSLANLIFRLY--PVTNGTIYIDGVDIRTVGLVKLRRGISAIAQDPSLFSGTVRFNLDPSLEYSDSMIWEALEKCHLKTLVQSL 1239          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSD 3860
            +  L  KL + VS GG+N SVG+RQL C+ARALL +++++++DEATA+VD  TD LIQ+ +++ FA  TV+ IAHRL  + N DRI+ + NG +  F  P  +F D
Sbjct: 1236 VQSLDKKLEADVSHGGNNFSVGERQLFCLARALLMKSRIVILDEATASVDAGTDKLIQEVIKTVFADATVIIIAHRLDNVRNMDRIMHLKNGKLINFTTPQEMFKD 1341          

Query:  329 LTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVA 823
            ++ + G+R++  + A++Y+ +L  N K L   T   +IN+ ++D  +   ++ F   + +GPLV V     L M      L  I+V  +    Q  LGK     R L +  T++RI M++E+I  +++VKM  WE +F   I + R++  +       A+SL +A
Sbjct:  215 VSYRTGIRVRGAVLALLYKNVL--NSKDLCGKTESDVINIFANDGQRLFDAVTFAPLVLVGPLVLVGGIGYLLMVIGRWSLLGILVFFVFDVIQFGLGKSMVACRNLAIVKTEKRISMMAEIIKYIRIVKMNGWEQIFSAKIDQFRKEEKVQIRKSGYAQSLAIA 377          

Query: 3570 SPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLI-QKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNG-IVDQFDHPHLLFSDRPDSTFI 3881
            + V E G+ LS GQ+  + +ARA+ +   + + D+  A++D    + I ++ +Q       ++ + + +  + + DR++ +  G IV   +H  L   +    TF+
Sbjct:  600 TEVGERGATLSGGQKARVALARAVFQTKNLYLFDDIFASLDKKVANKIHEEIIQKLLKKKALMMVTNNMELLHHFDRVLFVEGGNIVADGNHDILYEKNDAYKTFV 705          

Query: 2758 HISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVC--TVFIVTAIYSCVALVYHKK--INTSDFGLVLNYVVGLIG--LTQWAVRQSSEVENQMTSIERIYEYIALP--TEYPKLTKE---LDSQLIDW---PSTGRIEF-------QNVSLYYEGPD-QCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL 3477
             IS   + +  IR  K   W  + F  K D++ K   + I  S  +A  L   C   V +V AI + V +V      + +  F  +  Y V L G  +  +  R  +E    + ++ RI EY+ L     YP    E   LD Q   +   P   +          +N  +  E P   C      L I+  E I ++G  G GKS+++              K I      +   L   R+    +PQ   +F GT++ N+
Sbjct:  327 RISMMAEIIKYIRIVKMNGW-EQIFSAKIDQFRKEEKVQIRKS-GYAQSLAIACGPVVPVVAAILTFVGVVLAGNDLLASDAFSAITVYFVMLFGIRMIPYGSRYLAEA---VVAMRRIQEYLLLEQYAPYPVTNAEDVVLDCQGATYTYQPKAAKAPVDETKEPTENEVIVVETPVFTCSFDK--LSIKRGEHIAVIGAVGCGKSAIL--------------KAISGHMFTTDDALSVDRSQTVYVPQKAWIFNGTVQDNI 567          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKN-NQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPD---QCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++  A+WN +   E +L++I+ SL  PQ  A+IG +GSGKSS+  A+LGELP   G +   G +SY SQ+PW+F+ S+  NILF LP + +++   I   AL+RD E++  +  T VGERG  LSGGQ+ARISLARA Y  AD  LLDDPL+AVD  VG  +F +C+    +DKLV+LVTHQL  L+  D I+++ +G + A GT+ E++  G D   +L  +  E + D ++   N +     +   D++T   +R SS+   V + S        S+  S  +   +   E  S   + L +Y KYF+ G     V+L+      T  L    D +LS+W    D  +++D   +          I   L  FA  LL  +  F + ++S   LH  M   +  + + FF+ N +GRILNRF+ D+   D++LP  + D I     +   +G+    N W +I  + + + F  LR  Y++ S  +KRLEA+ RSP+++H S TL GL+TIRA ++Q+   KE+   QD +S  ++ ++S++R F + LD  C  ++++   + ++       N    GLV+   + + G  QW +RQS+E+EN MTS+ER+ EY  L  E    + +     ++WP  G I  + +SL Y  PD     VLK++N +I  REKIGIVGRTGAGKSSLI+ LFRL     + G +++D  DI  +GL  LR+ I++IPQ+PVLF GT+R NLDPF ++ D  +   L+
Sbjct:  412 VKLQSFQARWNHDHV-EPVLENINISLSPPQLVAVIGPVGSGKSSLIQAILGELPGESGKLKVQGDISYASQEPWLFNASVRDNILFGLPMDKHRYRNVIRNCALERDFELLHGDR-TFVGERGASLSGGQRARISLARAVYRQADTYLLDDPLSAVDTHVGRHLFEECMRGFLRDKLVILVTHQLQFLEHADLIVIMDKGKISAVGTYEEMLKSGQDFGKLLATEAQE-MGDSNQEQVNAEG----DSRNDKSTY--SRQSSRVSRVSVTS------VDSSTESILDNERQPAQESRSQGKIGLGIYGKYFSAGSGWLMVILVAFFCLGTQILASGGDYFLSYWVKNNDSSSSTDIYIFSG--------INAALVIFA--LLRTLLFFSMAMHSSTQLHNTMFQGVSRTALYFFHANPSGRILNRFAMDLGQVDEILPAVMLDCIQIFLTISGIIGVLCITNPWYLINTITMFLAFHFLRTFYLSTSRDLKRLEAIARSPMYSHFSATLNGLSTIRAMEAQDLLTKEYDNYQDIHSSGYYTFLSTNRAFGYYLDLFCVAYVISV--TLMSYFNPPVDNPGQIGLVITQAMSMTGTVQWGMRQSAELENSMTSVERVLEYRHLEAEGEFESPDDKKPPMNWPQEGLISAEQLSLRYN-PDPKADRVLKSLNFIIMPREKIGIVGRTGAGKSSLINALFRL---SYNEGSLVIDNTDILGIGLHDLRSKISIIPQEPVLFSGTLRCNLDPFEQYADEKLWEALE 1143          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L D +++LP+ L S V+EGGSN SVGQRQL+C+ARA+L+  +++V+DEATANVD  TD+LIQ T++  F  CTVLTIAHRL+TI++SDR++V++ G + +F  P  L +      F  +V QTG +  + L K+A
Sbjct: 1147 LKDEVSELPNGLESVVAEGGSNYSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQSTIRRKFRDCTVLTIAHRLNTIIDSDRVMVLDAGTLVEFGSPFELLTQSWSKVFYGMVLQTGRSSFEHLLKLA 1281          

Query:  314 NPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLA--KSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            +P     M + M++++ +   +Y K L+L++ ALG TT+GQ++NL+S+D+ +F+ +L   HF+W+GPL  + ++  LY     A L  I++LL+ +P Q  L +L  + R      TD+R++M++E+I+G+QV+KMY WE  F ++I +LRR  +    +RK+   +   ++   + SR  I   +    L+G  L+++  +      N +R ++   F  G++   ++ VT  RI+
Sbjct:  150 HPLMMGLMHLAMKMRVAVSTAIYRKALRLSRTALGDTTTGQVVNLISNDLGRFDRALIHFHFLWLGPLELLISSYFLYQQIGVASLYGIVILLLFLPIQTFLSRLTSRLRHQTALRTDQRVRMMNEIISGIQVIKMYTWEKPFGRLIERLRRSEM--SSIRKVNYIRGTLLSFEITLSRIAIFVSLLGFVLMGGELTAERAFSVTAFYNILRRTVCKFFPSGMSQFAEMMVTLRRIK 384          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQ-DTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCS--AFFVVLMFILYATTMTLYVFTDIWLSWWTTEMD----KRNASDAEFYKNDKPFL------IGL---------ILLTLSTFAGGLLSVICLFLICIYSCKA---LHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLA-SYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPD---QCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            + ++   + AKW+ N + +Y L  ++  ++      I+G  GSGKSS+  A+LGELP   G I   GS+SY SQ+PW+FSG++ QNILF  P + + + + +   AL+RD E++P +  T VGERG  LSGGQKARISLARA Y    I LLDDPL+AVD  V   +F QC+    ++++V+L THQL  L+  D+I+++ +G + A GT+  +   G+D  S+L   +  E   ++SR+       Y    ++ R      RNS  EQ++  ++     +  +      N   R E  Q     + L LY KYF  G    AFFV++ F +   +  L    D +LS+W T+      + + +D    +  +P L      IGL          + T+ T    L++V   FL    + KA   LH  M   I  + + FFN N +GRILNRFSKD+   D++LP  + D ++   L L G+ +  +  N   +I  + L IIF+ LR  Y+  S  +KR+EA+TRSP+++H++ +L GL+TIRAF +Q     EF   QD +S AF+++IS+SR F + LD  C ++I  AI +    ++    N  D GL +   +G+ G+ QW +RQS+E+EN MT++ER+ EY  +  E              WP  G+I F  +SL Y  PD   + VLK+++ +I+ +EK+GIVGRTGAGKSSLI+ LFRL     + G +++D++D S +GL  LR+ I++IPQ+PVLF GT+R NLDPF+E++D  +   L+
Sbjct:  443 AGISISGLMAKWDVN-SPDYSLNGVNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEIKVNGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYAKVVKKCALERDFELLPFKDKTIVGERGASLSGGQKARISLARAVYRETSIYLLDDPLSAVDTHVARHLFEQCMRGYLRERIVILATHQLQFLQHADQIVIMDKGRVSAVGTYESLRESGLDFASMLADPERDEQSEERSRS---RSGSYTHSHSDQR------RNS--EQSLLSMADSCMDDLEAE---QANNQERQEAGQ-----IGLRLYSKYFKAGGGFFAFFVMMGFCVL--SQGLASLGDYFLSYWVTKKGNVAYRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTYIFTVITVLTILVTVARSFLFFNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMD-VIQIFLALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAASLTGLSTIRAFGAQRVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCFCVIYI--AIITLSFFIF-PPANGGDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAPADKKPPKSWPEQGKIVFDELSLRYT-PDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL---SYNDGSVLIDKRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDDKLWRSLE 1203          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + +  LP  L S ++EGG+N SVGQRQL+C+ARA+L+  +++V+DEATANVD  TD LIQ T+++ F  CTVLTIAHRL TIM+SD+++V++ G   +F  P+ L +      F  +V+QTG A  + L K+A
Sbjct: 1207 LKEVVADLPSGLQSKITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAHRLHTIMDSDKVLVMDAGRAVEFGTPYELLTLADSKVFHGMVKQTGHATYESLLKIA 1341          

Query:   71 EWEKEQRRNKPSLIKCVCRII-WKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIM---VLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL----LYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E E E+ + KP+L++ + R+  W       +L   E  +   QP  + KL+++    +E++     Y+  +I+   L V+I +PY   TM +G+++++G+ +++Y K L+L++ ALG TT+G ++NLMS+D+ + + +  F+H++W+GPL T+  T ++Y   RE G+A++     +L+ IP Q  LGK     R      TDER++M++E+I+G+QV+KMY WE  F  ++A  R+K +       ++R +  S  + L    +R  I   +    L+G  L+ ++ +L     N +R ++   F  GI+   +  V+  R+Q
Sbjct:   66 ELELEKTKGKPNLLRALLRVFGWYFALLGLVLFLLELGLRTLQPIFLLKLIAYYTHGSESIESAYYYAAGVILCSALNVIIMHPYMLGTMHVGLKMRVGMCSMIYRKALRLSKSALGDTTAGHVVNLMSNDVGRLDLATIFVHYLWVGPLETLFITYLMY---REIGIAAVFGVAFMLLFIPLQAYLGKRTSVLRLRTALRTDERVRMMNEIISGIQVIKMYAWELPFEHMVAFARKKEINAIRHVSYIRGILLSFIIFL----TRVSIFLSLVGYVLLGTFLTPEVAFLITAYYNILRTTMTVFFPQGISQMAETLVSIKRVQ 382          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQ-DTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCS--AFFVVLMFILYATTMTLYVFTDIWLSWWTTEMD----KRNASDAEFYKNDKPFL------IGL---------ILLTLSTFAGGLLSVICLFLICIYSCKA---LHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLA-SYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPD---QCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            + ++   + AKW+ N + +Y L  ++  ++      I+G  GSGKSS+  A+LGELP   G I   GS+SY SQ+PW+FSG++ QNILF  P + + + + +   AL+RD E++P +  T VGERG  LSGGQKARISLARA Y    I LLDDPL+AVD  V   +F QC+    ++++V+L THQL  L+  D+I+++ +G + A GT+  +   G+D  S+L   +  E   ++SR+       Y    ++ R      RNS  EQ++  ++     +  +      N   R E  Q     + L LY KYF  G    AFFV++ F +   +  L    D +LS+W T+      + + +D    +  +P L      IGL          + T+ T    L++V   FL    + KA   LH  M   I  + + FFN N +GRILNRFSKD+   D++LP  + D ++   L L G+ +  +  N   +I  + L IIF+ LR  Y+  S  +KR+EA+TRSP+++H++ +L GL+TIRAF +Q     EF   QD +S AF+++IS+SR F + LD  C ++I  AI +    ++    N  D GL +   +G+ G+ QW +RQS+E+EN MT++ER+ EY  +  E              WP  G+I F  +SL Y  PD   + VLK+++ +I+ +EK+GIVGRTGAGKSSLI+ LFRL     + G +++D++D S +GL  LR+ I++IPQ+PVLF GT+R NLDPF+E++D  +   L+
Sbjct:  443 AGISISGLMAKWDVN-SPDYSLNGVNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEIKVNGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYAKVVKKCALERDFELLPFKDKTIVGERGASLSGGQKARISLARAVYRETSIYLLDDPLSAVDTHVARHLFEQCMRGYLRERIVILATHQLQFLQHADQIVIMDKGRVSAVGTYESLRESGLDFASMLADPERDEQSEERSRS---RSGSYTHSHSDQR------RNS--EQSLLSMADSCMDDLEAE---QANNQERQEAGQ-----IGLRLYSKYFKAGGGFFAFFVMMGFCVL--SQGLASLGDYFLSYWVTKKGNVAYRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTYIFTVITVLTILVTVARSFLFFNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMD-VIQIFLALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAASLTGLSTIRAFGAQRVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCFCVIYI--AIITLSFFIF-PPANGGDVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAPADKKPPKSWPEQGKIVFDELSLRYT-PDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL---SYNDGSVLIDKRDTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDDKLWRSLE 1203          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + +  LP  L S ++EGG+N SVGQRQL+C+ARA+L+  +++V+DEATANVD  TD LIQ T+++ F  CTVLTIAHRL TIM+SD+++V++ G   +F  P+ L +      F  +V+QTG A  + L K+A
Sbjct: 1207 LKEVVADLPSGLQSKITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAHRLHTIMDSDKVLVMDAGRAVEFGTPYELLTLADSKVFHGMVKQTGHATYESLLKIA 1341          

Query:   71 EWEKEQRRNKPSLIKCVCRII-WKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIM---VLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL----LYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E E E+ + KP+L++ + R+  W       +L   E  +   QP  + KL+++    +E++     Y+  +I+   L V+I +PY   TM +G+++++G+ +++Y K L+L++ ALG TT+G ++NLMS+D+ + + +  F+H++W+GPL T+  T ++Y   RE G+A++     +L+ IP Q  LGK     R      TDER++M++E+I+G+QV+KMY WE  F  ++A  R+K +       ++R +  S  + L    +R  I   +    L+G  L+ ++ +L     N +R ++   F  GI+   +  V+  R+Q
Sbjct:   66 ELELEKTKGKPNLLRALLRVFGWYFALLGLVLFLLELGLRTLQPIFLLKLIAYYTHGSESIESAYYYAAGVILCSALNVIIMHPYMLGTMHVGLKMRVGMCSMIYRKALRLSKSALGDTTAGHVVNLMSNDVGRLDLATIFVHYLWVGPLETLFITYLMY---REIGIAAVFGVAFMLLFIPLQAYLGKRTSVLRLRTALRTDERVRMMNEIISGIQVIKMYAWELPFEHMVAFARKKEINAIRHVSYIRGILLSFIIFL----TRVSIFLSLVGYVLLGTFLTPEVAFLITAYYNILRTTMTVFFPQGISQMAETLVSIKRVQ 382          

Query: 1213 KPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQ--DTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCS--AFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKR-------NASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPV----TLQDFILSTCLVLFG--LGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEG--PDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            KP P + + C S++   + AKW  N + +Y L  ++  + A    AI+G  GSGKSS+  A+LGEL +  G I  TGS+SY SQ+PW+FSG++ QNILF  P + + ++  +   AL+RD E++P +  T +G+RG  LSGGQKARISLAR+ Y  A I LLDDPL+AVD++V  ++F +C+    +DK+V+LVTHQL  L+  D+I+++  G + A GT+  +   G+D   +L    +  E   D+SRT         S IT+ R +++ +  S  E       P   GE         NL    + +Q   +   L +Y  YF  G    +F VV+ F  +  +  L    D +LS W +  +K        +A DA+F  +     +   L+T+ +    +      F + + +   LH  M   I  + + FFN+N AG ILNRFSKD+   D++LP      +QDF+L      FG  + + +  N   +I  L   I+ + LR  Y+  S  +KRLEA TRSP+++H + +L GL+TIRAF + +    EF   QD +S A +++IS+SR FA+ +D  C +FI  A+ +    ++    + +D GL +   +GL G  QW VRQS+E+EN M S+ER+ EY  +  E P            WP  G+IEF  +SL YE     + VLK+++ +I+ +EK+GIVGRTGAGKSSLI+ LFRL     + G + +D +D + +GL  LR+ I++IPQ+PVLF GT+R NLDPF+E++D  +   L+
Sbjct:  425 KP-PHNSEDCVSIS--ELKAKWTTN-SPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDFGIVLDDPVNDNEAAEDRSRT---------SSITDQRRSSVKSVLSHAESC-----PEDVGE-----EQKINL----QRQQLGRNG--LGVYVDYFRAGGGFLSFSVVMTF--FVCSQGLASLGDYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAAYIYM---LITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLL------FGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIFCVLFI--AMITLSFFIFPPS-SAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL---SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALE 1169          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L D +  +   L + ++EGGSN SVGQRQL+C+ARA+L+  +++V+DEATANVD  TD+LIQ T+++ F  CTVLT+AHRL TIM+SDR++V++ G V +F  P+ L +    + F  LV+QTG A    L K++
Sbjct: 1173 LKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQATYDTLLKIS 1307          

Query:   68 SEWEKEQRRNK--PSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLS-FCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIM---VLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKS---LWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            S W  E   NK   SL++ + R+  + + FLGL+LF    I   QP  + KL+S F N    +      Y+  +I+   L V++ NPY F    +G+++++G+ +++Y K L+L +  LG+ ++G IINL+S+D+ + +  +QF H++W+ PL  +  T ++Y   +E G+A++     +L+ IP Q+ LGK     R      +D+R+++++E+I G+QV+KMY WE  F K++A  R K +    +R +A +   +W   RF     I ++ +    L+G  L++++ +L     N +R ++   FS+G+T   +  V+  R+Q
Sbjct:   63 SSWANELETNKKNASLLRVLFRVFGRYFVFLGLVLFCLEVILTVQPMFLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMY---QEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEI--NSIRHVAYAKCLIWSFNRFLTPVSIFLS-LVGFVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQ 382          

Query: 1213 KPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQ--DTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCS--AFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKR-------NASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPV----TLQDFILSTCLVLFG--LGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEG--PDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            KP P + + C S++   + AKW  N + +Y L  ++  + A    AI+G  GSGKSS+  A+LGEL +  G I  TGS+SY SQ+PW+FSG++ QNILF  P + + ++  +   AL+RD E++P +  T +G+RG  LSGGQKARISLAR+ Y  A I LLDDPL+AVD++V  ++F +C+    +DK+V+LVTHQL  L+  D+I+++  G + A GT+  +   G+D   +L    +  E   D+SRT         S IT+ R +++ +  S  E       P   GE         NL    + +Q   +   L +Y  YF  G    +F VV+ F  +  +  L    D +LS W +  +K        +A DA+F  +     +   L+T+ +    +      F + + +   LH  M   I  + + FFN+N AG ILNRFSKD+   D++LP      +QDF+L      FG  + + +  N   +I  L   I+ + LR  Y+  S  +KRLEA TRSP+++H + +L GL+TIRAF + +    EF   QD +S A +++IS+SR FA+ +D  C +FI  A+ +    ++    + +D GL +   +GL G  QW VRQS+E+EN M S+ER+ EY  +  E P            WP  G+IEF  +SL YE     + VLK+++ +I+ +EK+GIVGRTGAGKSSLI+ LFRL     + G + +D +D + +GL  LR+ I++IPQ+PVLF GT+R NLDPF+E++D  +   L+
Sbjct:  425 KP-PHNSEDCVSIS--ELKAKWTTN-SPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDFGIVLDDPVNDNEAAEDRSRT---------SSITDQRRSSVKSVLSHAESC-----PEDVGE-----EQKINL----QRQQLGRNG--LGVYVDYFRAGGGFLSFSVVMTF--FVCSQGLASLGDYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAAYIYM---LITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLL------FGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIFCVLFI--AMITLSFFIFPPS-SAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRL---SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALE 1169          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L D +  +   L + ++EGGSN SVGQRQL+C+ARA+L+  +++V+DEATANVD  TD+LIQ T+++ F  CTVLT+AHRL TIM+SDR++V++ G V +F  P+ L +    + F  LV+QTG A    L K++
Sbjct: 1173 LKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQATYDTLLKIS 1307          

Query:   68 SEWEKEQRRNK--PSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLS-FCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIM---VLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKS---LWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            S W  E   NK   SL++ + R+  + + FLGL+LF    I   QP  + KL+S F N    +      Y+  +I+   L V++ NPY F    +G+++++G+ +++Y K L+L +  LG+ ++G IINL+S+D+ + +  +QF H++W+ PL  +  T ++Y   +E G+A++     +L+ IP Q+ LGK     R      +D+R+++++E+I G+QV+KMY WE  F K++A  R K +    +R +A +   +W   RF     I ++ +    L+G  L++++ +L     N +R ++   FS+G+T   +  V+  R+Q
Sbjct:   63 SSWANELETNKKNASLLRVLFRVFGRYFVFLGLVLFCLEVILTVQPMFLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMY---QEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEI--NSIRHVAYAKCLIWSFNRFLTPVSIFLS-LVGFVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQ 382          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL +P++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ELRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAEMLHNRMFNSILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL + ++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ESRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAETLHNRMFNSILRTQVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1222 PLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEII-SQG------VDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEIT---EDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDEL---EQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNA--------------SDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFI----------LSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEV-CTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            P D DK +S   EN          ++  L++IS +L       + G +GSGK+S+  ++L ++ L  G +   G+L+Y SQQ WIF G++  NIL   P    ++   I A  L  D+ I+P    T +GERG+ LSGGQK R+SLARA Y   DI LLDDPL+AVDA VG  IF +CI +  K K V+LVTHQL  L+  D++++L  G +   GT ++++ ++G       +VH  L+Q+  E    K +T  N+     SE T   E +A  + N         P      T ET  + S       +D+L   E     +V    Y +Y         + L+ +L+   +    F++ WLS+W  +    N+               D  FY+     + G+I++ +   +  +L       + + S   LH+ M   IL SP+ FF+    GR++NRFSKD    D +LP  +++F+          L+ C+V   L +A       +I+ L    I +  +RS  +    +KR+E V+RSP  +  ++T+QGL+TI A+  +  + + F+   D  S  F L+ + +RW +F LD +  TV ++ +++  V L  ++ IN S  GL L+Y + L G+ Q+ VR S+EVE + TS+ER+ EYI +  +E P+  K+ +     WP  G I F+N S+ Y      VL N+N+ I   EK+GIVGRTG+GKSSL   LFRL E P + G I++D  DI  LGLK LR+ ++VIPQDPVLF+GT+R NLDPFN + D ++   L+ +
Sbjct:  468 PTD-DKNTSQMPENPSQNGKHKAESQPSLRNISLTLSKGSLLGVCGNVGSGKTSLISSILEQMHLLSGSVSANGTLAYVSQQAWIFHGTVRDNILMGEPFDEARYASVINACCLKPDLAILPYGDQTEIGERGINLSGGQKQRVSLARAVYSNRDIFLLDDPLSAVDAHVGKHIFEECIKKELKGKSVILVTHQLQYLEFCDEVMLLDNGEIKEAGTHSDLMKTKGRYSQLITNVH--LEQNN-ERADSKPQTEHND-----SEQTNPDEPKANGIENPAFDMSDEKP-----ATNETPKDSSETKG--KKDQLVTREVAQEGSVTWRTYHQYCQAAGGYILLFLVVLLFTLLVGSTAFSNWWLSYWLDQGSGNNSSSNATSNSGNISENPDLSFYQ----MVYGVIIIAMIVLS--ILKGYTFTKVTLRSSSKLHDTMFKRILGSPMSFFDTTPTGRLVNRFSKDQDEVDAVLPFNMENFLQFCLIVTFTLLTICIVFPFLLIAV------VILGLIFATILYVFQRSIRH----MKRMENVSRSPWISLTTSTIQGLSTIHAYDKRQQYIERFKMLSDNNSNHFMLFNAGTRWLSFWLDVLSATVTLIVSLF--VVLSPNETINPSLKGLALSYTIQLTGILQFVVRLSTEVEAKFTSVERLLEYITSCVSEGPRRVKDANIP-AGWPQEGTITFKNYSMRYRDNTPIVLDNLNITIRPGEKLGIVGRTGSGKSSLGVALFRLAE-PAE-GTILIDDMDICKLGLKDLRSQLSVIPQDPVLFIGTVRYNLDPFNNYKDEELWLALEKT 1240          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLV 3890
            + DTI+KLP+KL SPV E G N SVG+RQL+CMARALL+ +K+I++DEATA++D  TDSLIQ T++  F HCT+LTIAHR++T++ SDRI+V++ G V +FD P  L   RP+S F  L+
Sbjct: 1242 MKDTISKLPEKLQSPVVENGENFSVGERQLMCMARALLRNSKIILLDEATASIDSETDSLIQHTIRDGFQHCTMLTIAHRINTVLESDRILVMDQGKVIEFDPPQDLI-QRPNSLFASLL 1360          

Query:  329 LTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLL----YGFVRKLAKSL 814
            + ++  +R+K     + ++KI+ L  ++L   T G+ IN+++SD ++   ++ F  F+   P++ +   +          L  I+V LI +P Q S+ +L   FR   +S+TD+R++ ++E++  ++++KMY WE  F K I  +R+   L     G+V+ L  SL
Sbjct:  209 VNLRTAVRVKGAFSMLAFKKIISL--RSLTTITVGETINVLTSDGYRLFDAVIFGTFLLCVPVLLIICIIYACFILGYTALIGILVYLIFLPIQFSIARLIGVFRRRAVSVTDKRVRTMNEVLTCIKLIKMYAWEESFEKSITDIRKNEKLLLQKAGYVQSLNSSL 372          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK---QDTTEYVIDK----SRTTFNEDAIYVSEITEDRA---------TNLNNRNSSKE-QTVPLLSPVITGETASNVSSACNLSSRD-----ELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTE-MDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLIC---IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++V+  N    W  +   E +LK +S  +K  +  A++G +GSGK+S+  ALLGEL   KG+I   GS++Y  QQ WI + ++  NILF    + + ++  I A AL+ D++++P    T +GE+G+ LSGGQK R+SLARA Y  AD+ LLDDPL+AVD+ VG  +F + I    L +DK  +LVTH +  L  VD+I+VL  G +   G++  + +        L+   +D +    DK    ++T   E+   + E  E +A         + L   NS +  Q     +  +     S++ +  +   +      E E      VK ++Y +Y +     ++V   F+ Y       +  ++WLS WT + ++  N +     ++ +  + G + L     A G L      L+    I + + LH  +L +IL  P+ FF+   +GRI+NRF+KDI   D+++P++ + +IL    VL  L +          +++ + ++++ ++R Y+  S  ++RL++V+RSP+++H   T+ GL+ IRA+  Q+ F K  +   D+  K+ + +I S+RW A RL+ +  + +  A  +  A++    +N+   GL ++Y + +     W VR +SE+E  + ++ER+ EY  +  E P +T        DWPS G I F++  + Y    + VL  V   I+  EKIGIVGRTGAGKSSL + LFR+VE     G+I++D  DI+TLGL  LR+ + +IPQDPVLF GT+R NLDPF  F+D+++ +VL+
Sbjct:  654 AAVSMTNGTYAWERD--TEPVLKQVSLDIKPGRLVAVVGAVGSGKTSLVSALLGELHSIKGNININGSVAYVPQQAWIQNATLKDNILFGSSVDEERYQSVIKACALEPDLDLLPGRDQTEIGEKGINLSGGQKQRVSLARAVYSSADVYLLDDPLSAVDSHVGKHLFEKVIGPNGLLRDKTRILVTHGISFLPYVDEIVVLVHGVVSEIGSYESLRASKGAFSEFLETYGKDESNKDNDKKAAAAQTPVYEEIETLPEGLETQADGSPEDIVSSTLKRENSLRHSQRHSKRNGSVKVRKNSSLRAQKDPEDKKGQRLIEKEMMETGRVKFSVYLQYLS-AMGWWYVGFSFVFYFIQNVAVIGQNLWLSDWTDDSIEYFNQTYPNHIRDTRIGVFGALGL-----AQGFLVFFGTILLADGSISASRTLHTSLLTNILKVPMMFFDTTPSGRIVNRFAKDIFTVDEMIPMSFRSWILCLLGVLGTLFVICLATPIFTAVVVPMAVVYYFVQRFYVATSRQLRRLDSVSRSPIYSHFGETVSGLSVIRAYGHQDRFLKHNEDTIDQNLKSVYPWIVSNRWLAMRLESLGNLVVFFA--ALFAVISRDSLNSGLVGLSISYALNVTQTLNWLVRMTSELETNIVAVERVREYAEIQNEAPWVTSVRPPD--DWPSAGNIRFEDYKVRYRPELELVLHGVTCDIQSTEKIGIVGRTGAGKSSLTNCLFRIVEAAD--GRILIDDIDIATLGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFQTFSDAEIWSVLE 1429          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFS 3857
            L + +  LP  L   VSEGG NLS+GQRQL+C+ARALL++++++++DEATA VDL TD LIQ T++  F+HCTVLTIAHRL+TI++S R++V+++G + +FD P+ L S
Sbjct: 1433 LKEYVRGLPTGLEHEVSEGGENLSLGQRQLLCLARALLRKSRILILDEATAAVDLETDDLIQSTIRREFSHCTVLTIAHRLNTILDSSRVMVLDSGKIVEFDSPNELLS 1541          

Query:  341 MGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL 778
            +GM+++  I A VY+K L ++  +  ++T+G+I+NLMS+D  +F     F+H +W  PL    +   L++    + L+ ++V+++++P    L     +F+   +   D R+K+V++L+NG++++K Y WE  F   + ++R K L
Sbjct:  407 LGMKVRTAIMAAVYKKALVVSNDSRKESTAGEIVNLMSADAQRFNDVTNFIHLLWSCPLQIALSIAFLWIELGPSVLSGLLVMVLMVPINGWLATKSRQFQMQNMKFKDSRMKIVNDLLNGIKILKYYAWETSFEAQVQEIREKEL 552          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDS-LIQKTL--QSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKK 3920
            LP +  + + E G NLS GQ+Q + +ARA+   A V ++D+  + VD H    L +K +         T + + H +S +   D I+V+ +G+V +      L + +    F + ++  G  E  K
Sbjct:  765 LPGRDQTEIGEKGINLSGGQKQRVSLARAVYSSADVYLLDDPLSAVDSHVGKHLFEKVIGPNGLLRDKTRILVTHGISFLPYVDEIVVLVHGVVSEIGSYESLRASK--GAFSEFLETYGKDESNK 888          

Query: 3175 TGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL 3477
            T  +   N +  +E   + VLK V+L I+    + +VG  G+GK+SL+S L          G++   + +I+  G      S+A +PQ   +   T++ N+
Sbjct:  653 TAAVSMTNGTYAWERDTEPVLKQVSLDIKPGRLVAVVGAVGSGKTSLVSALL---------GELHSIKGNINING------SVAYVPQQAWIQNATLKDNI 738          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK---QDTTEYVIDK----SRTTFNEDAIYVSEITEDRA---------TNLNNRNSSKE-QTVPLLSPVITGETASNVSSACNLSSRD-----ELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTE-MDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLIC---IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++V+  N    W  +   E +LK +S  +K  +  A++G +GSGK+S+  ALLGEL   KG+I   GS++Y  QQ WI + ++  NILF    + + ++  I A AL  D++++P    T +GE+G+ LSGGQK R+SLARA Y  AD+ LLDDPL+AVD+ VG  +F + I    L +DK  +LVTH +  L  VD+I+VL  G +   G++  + +        L+   +D +    DK    ++T   E+   + E  E +A         + L   NS +  Q     +  +     S++ +  +   +      E E      VK ++Y +Y +     ++V   F+ Y       +  ++WLS WT + ++  N +     ++ +  + G + L     A G L      L+    I + + LH  +L +IL  P+ FF+   +GRI+NRF+KDI   D+++P++ + +IL    VL  L +          +++ + ++++ ++R Y+  S  ++RL++V+RSP+++H   T+ GL+ IRA+  Q+ F K  +   D+  K+ + +I S+RW A RL+ +  + +  A  +  A++    +N+   GL ++Y + +     W VR +SE+E  + ++ER+ EY  +  E P +T        DWPS G I F++  + Y    + VL  V   I+  EKIGIVGRTGAGKSSL + LFR+VE     G+I++D  DI+TLGL  LR+ + +IPQDPVLF GT+R NLDPF  F+D+++ +VL+
Sbjct:  640 AAVSMTNGTYAWERD--TEPVLKQVSLDIKPGRLVAVVGAVGSGKTSLVSALLGELHSIKGNININGSVAYVPQQAWIQNATLKDNILFGSSVDEERYQSVIKACALGPDLDLLPGRDQTEIGEKGINLSGGQKQRVSLARAVYSSADVYLLDDPLSAVDSHVGKHLFEKVIGPNGLLRDKTRILVTHGISFLPYVDEIVVLVHGVVSEIGSYESLRASKGAFSEFLETYGKDESNKDNDKKAAAAQTPVYEEIETLPEGLETQADGSPEDIVSSTLKRENSLRHSQRHSKRNGSVKVRKNSSLRAQKDPEDKKGQRLIEKEMMETGRVKFSVYLQYLS-AMGWWYVGFSFVFYFIQNVAVIGQNLWLSDWTDDSIEYFNQTYPNHIRDTRIGVFGALGL-----AQGFLVFFGTILLADGSISASRTLHTSLLTNILKVPMMFFDTTPSGRIVNRFAKDIFTVDEMIPMSFRSWILCLLGVLGTLFVICLATPIFTAVVVPMAVVYYFVQRFYVATSRQLRRLDSVSRSPIYSHFGETVSGLSVIRAYGHQDRFLKHNEHTIDQNLKSVYPWIVSNRWLAMRLESLGNLVVFFA--ALFAVISRDSLNSGLVGLSISYALNVTQTLNWLVRMTSELETNIVAVERVREYAEIQNEAPWVTSVRPPD--DWPSAGNIRFEDYKVRYRPELELVLHGVTCDIQSTEKIGIVGRTGAGKSSLTNCLFRIVEAAD--GRILIDDIDIATLGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFQTFSDAEIWSVLE 1415          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFS 3857
            L + +  LP  L   VSEGG NLS+GQRQL+C+ARALL++++++++DEATA VDL TD LIQ T++  F+HCTVLTIAHRL+TI++S R++V+++G + +FD P+ L S
Sbjct: 1419 LKEYVRGLPTGLEHEVSEGGENLSLGQRQLLCLARALLRKSRILILDEATAAVDLETDDLIQSTIRREFSHCTVLTIAHRLNTILDSSRVMVLDSGKIVEFDSPNELLS 1527          

Query:  341 MGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL 778
            +GM+++  I A VY+K L ++  +  ++T+G+I+NLMS+D  +F     F+H +W  PL    +   L++    + L+ ++V+++++P    L     +F+   +   D R+K+V++L+NG++++K Y WE  F   + ++R K L
Sbjct:  393 LGMKVRTAIMAAVYKKALVVSNDSRKESTAGEIVNLMSADAQRFNDVTNFIHLLWSCPLQIALSIAFLWIELGPSVLSGLLVMVLMVPINGWLATKSRQFQMQNMKFKDSRMKIVNDLLNGIKILKYYAWETSFEAQVQEIREKEL 538          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDS-LIQKTL--QSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKK 3920
            LP +  + + E G NLS GQ+Q + +ARA+   A V ++D+  + VD H    L +K +         T + + H +S +   D I+V+ +G+V +      L + +    F + ++  G  E  K
Sbjct:  751 LPGRDQTEIGEKGINLSGGQKQRVSLARAVYSSADVYLLDDPLSAVDSHVGKHLFEKVIGPNGLLRDKTRILVTHGISFLPYVDEIVVLVHGVVSEIGSYESLRASK--GAFSEFLETYGKDESNK 874          

Query: 3175 TGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL 3477
            T  +   N +  +E   + VLK V+L I+    + +VG  G+GK+SL+S L          G++   + +I+  G      S+A +PQ   +   T++ N+
Sbjct:  639 TAAVSMTNGTYAWERDTEPVLKQVSLDIKPGRLVAVVGAVGSGKTSLVSALL---------GELHSIKGNINING------SVAYVPQQAWIQNATLKDNI 724          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPK-NNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEY-------VIDKSRT-TFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLIL-------LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++V   W++ +     L++IS S++  +  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y SQQPW+FSG++  NILF       ++++ +   AL +D+  + +  LT +G+RGV LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI +  + KL +LVTHQL  L +  +IL+L EG M+  GTF E++  G+D  S+LK +  E        +I  SR  TF++ +++  + T          N + E       PV+T         A    SR E        V   +Y KYFT G S   + ++ +L   +   +VF          E  K N +        K   + L L       LT++T   G+L  + +F + + + +ALH +M  S+L +P+ FF+ N  GRILNRFSKDI   DDL+P T  DF+     +L  + +A     W +I +L L+I+F+ LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRAFK++  F+  F  +QD +S+A+FL++++SRW A RLD +C VF++   +  + L   + ++    GL L+Y + ++G  QW VRQS+EVEN M S ER+ EY  L  E    +K  +    DWP+ G I F+NV+  Y      VL+++N +I  +EK+GIVGRTGAGKSSLI+ LFRL E P   GKI +D+   S LGL  LR  +++IPQ+PVLF GT+R NLDPF+E  D ++  VL+
Sbjct:  405 VQIQDVTCYWDKTLEIP-TLQNISCSVRPGELLAVIGPVGAGKSSLLSAVLGELPKDKGFVDIRGRIAYVSQQPWVFSGTVRSNILFGKEYVQEKYDKVLRVCALKKDMLQLDDGDLTIIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICQALRKKLCILVTHQLQYLSAAKQILILKEGRMVGKGTFQELLQSGIDFASLLKSEEEEQSQSQEGQLIKSSRNRTFSQSSVWSQDSTVQSHKEGATDNLAAE-------PVLT---------AIPEESRSE------GTVGFKVYKKYFTSGSSYLMLFVVLLLNILSQVSFVF----FLKKANEQGKLNITSGTNSTGSKTEQLDLTLYLGVYAGLTVATIIFGVLRCLLVFHVLVCAAQALHNQMFQSLLKAPVLFFDRNPIGRILNRFSKDIGHLDDLMPFTFLDFMQVLLQILGVIAVAVAVIPWILIPLLPLVIVFYFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEKRFQDLFDAQQDLHSEAWFLFLTTSRWLAVRLDAICAVFVIAIAFGSIILA--ENLDAGQVGLALSYGMTIMGSFQWGVRQSAEVENLMISAERVMEYTQLEKEAEWESK--NPPPADWPNKGMITFENVNFSYSLDGPVVLRHLNALIRPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GKIWIDKYLTSKLGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFDEHADEELWDVLE 1145          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + + +LP K+ + +SE GSN SVGQRQL+C+ARA+L+R ++++IDEATANVD  TD LIQKT++  FA CTVLTIAHRL+TI++SD+I+V++ G V ++D P+LL  ++ +S F ++VQQ G AE   L + A
Sbjct: 1149 LKEAVEELPGKIETQLSESGSNFSVGQRQLVCLARAILRRNRILIIDEATANVDPRTDELIQKTIREKFAECTVLTIAHRLNTIIDSDKIMVLDAGRVKEYDEPYLLLQNK-ESLFYKMVQQVGKAEATALNEAA 1282          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINET----LTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            WEKE ++      KP L K + R  WK +  LGL  FFE  I + QP  +  ++S+    +      L    I +  L    ++L ++ + Y++  ++ GM+L++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L+M    + LA + VL+IL+P Q+ LGK +   R    + TD RI+ ++E+I+GM+++KMY WE   I V+ K   K L   ++R    +L +A  F  S+ I+        L+G  +S+  V++ V L + +R ++   F   +  A + +V+  RI+
Sbjct:   61 WEKELQKAQNEGRKPRLTKAIIRCHWKTFSVLGLFTFFEESIRVVQPIFLGNVISYFERYDANDSAVLANAYINAAALSACTLILAVVHHIYFYHLLRAGMKLRVAMCHMIYRKALRLSNTAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWMEIGPSCLAGMAVLIILMPLQLCLGKFFTSLRGKTAAFTDTRIRTMNEVISGMRIIKMYAWEQSPIVVLRKEINKVLRSSYLR----ALNLASFFVASKIILFVTFTTYVLLGNVISASRVFVAVSLYSAVRLTVTLFFPSAVERASEAKVSIRRIK 380          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPK-NNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEY-------VIDKSRT-TFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLIL-------LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++V   W++ +     L++IS S++  +  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y SQQPW+FSG++  NILF       ++++ +   AL +D+  + +  LT +G+RGV LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI +  + KL +LVTHQL  L +  +IL+L EG M+  GTF E++  G+D  S+LK +  E        +I  SR  TF++ +++  + T           S KE   P+L+ +                     E  S   V   +Y KYFT G S   + ++ +L   +   +VF          E  K N +        K   + L L       LT++T   G+L  + +F + + + +ALH +M  S+L +P+ FF+ N  GRILNRFSKDI   DDL+P T  DF+     +L  + +A     W +I +L L+I+F+ LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRAFK++  F+  F  +QD +S+A+FL++++SRW A RLD +C VF++   +  + L   + ++    GL L+Y + ++G  QW VRQS+EVEN M S ER+ EY  L  E    +K  +    DWP+ G I F+NV+  Y      VL+++N +I  +EK+GIVGRTGAGKSSLI+ LFRL E P   GKI +D+   S LGL  LR  +++IPQ+PVLF GT+R NLDPF+E  D ++  VL+
Sbjct:  411 VQIQDVTCYWDKTLEIP-TLQNISCSVRPGELLAVIGPVGAGKSSLLSAVLGELPKDKGFVDIRGRIAYVSQQPWVFSGTVRSNILFGKEYVQEKYDKVLRVCALKKDMLQLDDGDLTIIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICQALRKKLCILVTHQLQYLSAAKQILILKEGRMVGKGTFQELLQSGIDFASLLKSEEEEQSQSQEGQLIKSSRNRTFSQSSVWSQDSTV---------QSHKEGAEPVLTAIPE-------------------ESRSEGTVGFKVYKKYFTSGSSYLMLFVVLLLNILSQVSFVF----FLKKANEQGKLNITSGTNSTGSKTEQLDLTLYLGVYAGLTVATIIFGVLRCLLVFHVLVCAAQALHNQMFQSLLKAPVLFFDRNPIGRILNRFSKDIGHLDDLMPFTFLDFMQVLLQILGVIAVAVAVIPWILIPLLPLVIVFYFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEKRFQDLFDAQQDLHSEAWFLFLTTSRWLAVRLDAICAVFVIAIAFGSIILA--ENLDAGQVGLALSYGMTIMGSFQWGVRQSAEVENLMISAERVMEYTQLEKEAEWESK--NPPPADWPNKGMITFENVNFSYSLDGPVVLRHLNALIRPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GKIWIDKYLTSKLGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFDEHADEELWDVLE 1145          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + + +LP K+ + +SE GSN SVGQRQL+C+ARA+L+R ++++IDEATANVD  TD LIQKT++  FA CTVLTIAHRL+TI++SD+I+V++ G V ++D P+LL  ++ +S F ++VQQ G AE   L + A
Sbjct: 1149 LKEAVEELPGKIETQLSESGSNFSVGQRQLVCLARAILRRNRILIIDEATANVDPRTDELIQKTIREKFAECTVLTIAHRLNTIIDSDKIMVLDAGRVKEYDEPYLLLQNK-ESLFYKMVQQVGKAEATALNEAA 1282          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINET----LTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            WEKE ++      KP L K + R  WK +  LGL  FFE  I + QP  +  ++S+    +      L    I +  L    ++L ++ + Y++  ++ GM+L++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L+M    + LA + VL+IL+P Q+ LGK +   R    + TD RI+ ++E+I+GM+++KMY WE  F +++  +R+K +         ++L +A  F  S+ I+        L+G  +S+  V++ V L + +R ++   F   +  A + +V+  RI+
Sbjct:   63 WEKELQKAQNEGRKPRLTKAIIRCHWKTFSVLGLFTFFEESIRVVQPIFLGNVISYFERYDANDSAVLANAYINAAALSACTLILAVVHHIYFYHLLRAGMKLRVAMCHMIYRKALRLSNTAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWMEIGPSCLAGMAVLIILMPLQLCLGKFFTSLRGKTAAFTDTRIRTMNEVISGMRIIKMYAWEQSFTELVNNIRKKEINKVLRSSYLRALNLASFFVASKIILFVTFTTYVLLGNVISASRVFVAVSLYSAVRLTVTLFFPSAVERASEAKVSIRRIK 386          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPK-NNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEY-------VIDKSRT-TFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLIL-------LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++V   W++ +     L++IS S++  +  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y SQQPW+FSG++  NILF       ++++ +   AL +D+  + +  LT +G+RGV LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI +  + KL +LVTHQL  L +  +IL+L EG M+  GTF E++  G+D  S+LK +  E        +I  SR  TF++ +++  + T          N + E       PV+T         A    SR E        V   +Y KYFT G S   + ++ +L   +   +VF          E  K N +        K   + L L       LT++T   G+L  + +F + + + +ALH +M  S+L +P+ FF+ N  GRILNRFSKDI   DDL+P T  DF+     +L  + +A     W +I +L L+I+F+ LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRAFK++  F+  F  +QD +S+A+FL++++SRW A RLD +C VF++   +  + L   + ++    GL L+Y + ++G  QW VRQS+EVEN M S ER+ EY  L  E    +K  +    DWP+ G I F+NV+  Y      VL+++N +I  +EK+GIVGRTGAGKSSLI+ LFRL E P   GKI +D+   S LGL  LR  +++IPQ+PVLF GT+R NLDPF+E  D ++  VL+
Sbjct:  403 VQIQDVTCYWDKTLEIP-TLQNISCSVRPGELLAVIGPVGAGKSSLLSAVLGELPKDKGFVDIRGRIAYVSQQPWVFSGTVRSNILFGKEYVQEKYDKVLRVCALKKDMLQLDDGDLTIIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICQALRKKLCILVTHQLQYLSAAKQILILKEGRMVGKGTFQELLQSGIDFASLLKSEEEEQSQSQEGQLIKSSRNRTFSQSSVWSQDSTVQSHKEGATDNLAAE-------PVLT---------AIPEESRSE------GTVGFKVYKKYFTSGSSYLMLFVVLLLNILSQVSFVF----FLKKANEQGKLNITSGTNSTGSKTEQLDLTLYLGVYAGLTVATIIFGVLRCLLVFHVLVCAAQALHNQMFQSLLKAPVLFFDRNPIGRILNRFSKDIGHLDDLMPFTFLDFMQVLLQILGVIAVAVAVIPWILIPLLPLVIVFYFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEKRFQDLFDAQQDLHSEAWFLFLTTSRWLAVRLDAICAVFVIAIAFGSIILA--ENLDAGQVGLALSYGMTIMGSFQWGVRQSAEVENLMISAERVMEYTQLEKEAEWESK--NPPPADWPNKGMITFENVNFSYSLDGPVVLRHLNALIRPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GKIWIDKYLTSKLGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFDEHADEELWDVLE 1143          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + + +LP K+ + +SE GSN SVGQRQL+C+ARA+L+R ++++IDEATANVD  TD LIQKT++  FA CTVLTIAHRL+TI++SD+I+V++ G V ++D P+LL  ++ +S F ++VQQ G AE   L + A
Sbjct: 1147 LKEAVEELPGKIETQLSESGSNFSVGQRQLVCLARAILRRNRILIIDEATANVDPRTDELIQKTIREKFAECTVLTIAHRLNTIIDSDKIMVLDAGRVKEYDEPYLLLQNK-ESLFYKMVQQVGKAEATALNEAA 1280          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINET----LTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            WEKE ++      KP L K + R  WK +  LGL  FFE  I + QP  +  ++S+    +      L    I +  L    ++L ++ + Y++  ++ GM+L++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L+M    + LA + VL+IL+P Q+ LGK +   R    + TD RI+ ++E+I+GM+++KMY WE  F +++  +R+K +         ++L +A  F  S+ I+        L+G  +S+  V++ V L + +R ++   F   +  A + +V+  RI+
Sbjct:   55 WEKELQKAQNEGRKPRLTKAIIRCHWKTFSVLGLFTFFEESIRVVQPIFLGNVISYFERYDANDSAVLANAYINAAALSACTLILAVVHHIYFYHLLRAGMKLRVAMCHMIYRKALRLSNTAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWMEIGPSCLAGMAVLIILMPLQLCLGKFFTSLRGKTAAFTDTRIRTMNEVISGMRIIKMYAWEQSFTELVNNIRKKEINKVLRSSYLRALNLASFFVASKIILFVTFTTYVLLGNVISASRVFVAVSLYSAVRLTVTLFFPSAVERASEAKVSIRRIK 378          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPK-NNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEY-------VIDKSRT-TFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLIL-------LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++V   W++ +     L++IS S++  +  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y SQQPW+FSG++  NILF       ++++ +   AL +D+  + +  LT +G+RGV LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI +  + KL +LVTHQL  L +  +IL+L EG M+  GTF E++  G+D  S+LK +  E        +I  SR  TF++ +++  + T          N + E       PV+T         A    SR E        V   +Y KYFT G S   + ++ +L   +   +VF          E  K N +        K   + L L       LT++T   G+L  + +F + + + +ALH +M  S+L +P+ FF+ N  GRILNRFSKDI   DDL+P T  DF+     +L  + +A     W +I +L L+I+F+ LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRAFK++  F+  F  +QD +S+A+FL++++SRW A RLD +C VF++   +  + L   + ++    GL L+Y + ++G  QW VRQS+EVEN M S ER+ EY  L  E    +K  +    DWP+ G I F+NV+  Y      VL+++N +I  +EK+GIVGRTGAGKSSLI+ LFRL E P   GKI +D+   S LGL  LR  +++IPQ+PVLF GT+R NLDPF+E  D ++  VL+
Sbjct:  358 VQIQDVTCYWDKTLEIP-TLQNISCSVRPGELLAVIGPVGAGKSSLLSAVLGELPKDKGFVDIRGRIAYVSQQPWVFSGTVRSNILFGKEYVQEKYDKVLRVCALKKDMLQLDDGDLTIIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICQALRKKLCILVTHQLQYLSAAKQILILKEGRMVGKGTFQELLQSGIDFASLLKSEEEEQSQSQEGQLIKSSRNRTFSQSSVWSQDSTVQSHKEGATDNLAAE-------PVLT---------AIPEESRSE------GTVGFKVYKKYFTSGSSYLMLFVVLLLNILSQVSFVF----FLKKANEQGKLNITSGTNSTGSKTEQLDLTLYLGVYAGLTVATIIFGVLRCLLVFHVLVCAAQALHNQMFQSLLKAPVLFFDRNPIGRILNRFSKDIGHLDDLMPFTFLDFMQVLLQILGVIAVAVAVIPWILIPLLPLVIVFYFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEKRFQDLFDAQQDLHSEAWFLFLTTSRWLAVRLDAICAVFVIAIAFGSIILA--ENLDAGQVGLALSYGMTIMGSFQWGVRQSAEVENLMISAERVMEYTQLEKEAEWESK--NPPPADWPNKGMITFENVNFSYSLDGPVVLRHLNALIRPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GKIWIDKYLTSKLGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFDEHADEELWDVLE 1098          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + + +LP K+ + +SE GSN SVGQRQL+C+ARA+L+R ++++IDEATANVD  TD LIQKT++  FA CTVLTIAHRL+TI++SD+I+V++ G V ++D P+LL  ++ +S F ++VQQ G AE   L + A
Sbjct: 1102 LKEAVEELPGKIETQLSESGSNFSVGQRQLVCLARAILRRNRILIIDEATANVDPRTDELIQKTIREKFAECTVLTIAHRLNTIIDSDKIMVLDAGRVKEYDEPYLLLQNK-ESLFYKMVQQVGKAEATALNEAA 1235          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINET----LTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            WEKE ++      KP L K + R  WK +  LGL  FFE  I + QP  +  ++S+    +      L    I +  L    ++L ++ + Y++  ++ GM+L++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L+M    + LA + VL+IL+P Q+ LGK +   R    + TD RI+ ++E+I+GM+++KMY WE  F +++  +R+K +         ++L +A  F  S+ I+        L+G  +S+  V++ V L + +R ++   F   +  A + +V+  RI+
Sbjct:   10 WEKELQKAQNEGRKPRLTKAIIRCHWKTFSVLGLFTFFEESIRVVQPIFLGNVISYFERYDANDSAVLANAYINAAALSACTLILAVVHHIYFYHLLRAGMKLRVAMCHMIYRKALRLSNTAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWMEIGPSCLAGMAVLIILMPLQLCLGKFFTSLRGKTAAFTDTRIRTMNEVISGMRIIKMYAWEQSFTELVNNIRKKEINKVLRSSYLRALNLASFFVASKIILFVTFTTYVLLGNVISASRVFVAVSLYSAVRLTVTLFFPSAVERASEAKVSIRRIK 333          

Query: 1249 VTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPK-NNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEY-------VIDKSRT-TFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLIL-------LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            V  ++V   W++ +     L++IS S++  +  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y SQQPW+FSG++  NILF       ++++ +   AL +D+  + +  LT +G+RGV LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI +  + KL +LVTHQL  L +  +IL+L EG M+  GTF E++  G+D  S+LK +  E        +I  SR  TF++ +++  + T          N + E       PV+T         A    SR E        V   +Y KYFT G S   + ++ +L   +   +VF          E  K N +        K   + L L       LT++T   G+L  + +F + + + +ALH +M  S+L +P+ FF+ N  GRILNRFSKDI   DDL+P T  DF+     +L  + +A     W +I +L L+I+F+ LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRAFK++  F+  F  +QD +S+A+FL++++SRW A RLD +C VF++   +  + L   + ++    GL L+Y + ++G  QW VRQS+EVEN M S ER+ EY  L  E    +K  +    DWP+ G I F+NV+  Y      VL+++N +I  +EK+GIVGRTGAGKSSLI+ LFRL E P   GKI +D+   S LGL  LR  +++IPQ+PVLF GT+R NLDPF+E  D ++  VL+
Sbjct:  409 VQIQDVTCYWDKTLEIP-TLQNISCSVRPGELLAVIGPVGAGKSSLLSAVLGELPKDKGFVDIRGRIAYVSQQPWVFSGTVRSNILFGKEYVQEKYDKVLRVCALKKDMLQLDDGDLTIIGDRGVTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICQALRKKLCILVTHQLQYLSAAKQILILKEGRMVGKGTFQELLQSGIDFASLLKSEEEEQSQSQEGQLIKSSRNRTFSQSSVWSQDSTVQSHKEGATDNLAAE-------PVLT---------AIPEESRSE------GTVGFKVYKKYFTSGSSYLMLFVVLLLNILSQVSFVF----FLKKANEQGKLNITSGTNSTGSKTEQLDLTLYLGVYAGLTVATIIFGVLRCLLVFHVLVCAAQALHNQMFQSLLKAPVLFFDRNPIGRILNRFSKDIGHLDDLMPFTFLDFMQVLLQILGVIAVAVAVIPWILIPLLPLVIVFYFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEKRFQDLFDAQQDLHSEAWFLFLTTSRWLAVRLDAICAVFVIAIAFGSIILA--ENLDAGQVGLALSYGMTIMGSFQWGVRQSAEVENLMISAERVMEYTQLEKEAEWESK--NPPPADWPNKGMITFENVNFSYSLDGPVVLRHLNALIRPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GKIWIDKYLTSKLGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFDEHADEELWDVLE 1149          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + + +LP K+ + +SE GSN SVGQRQL+C+ARA+L+R ++++IDEATANVD  TD LIQKT++  FA CTVLTIAHRL+TI++SD+I+V++ G V ++D P+LL  ++ +S F ++VQQ G AE   L + A
Sbjct: 1153 LKEAVEELPGKIETQLSESGSNFSVGQRQLVCLARAILRRNRILIIDEATANVDPRTDELIQKTIREKFAECTVLTIAHRLNTIIDSDKIMVLDAGRVKEYDEPYLLLQNK-ESLFYKMVQQVGKAEATALNEAA 1286          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINET----LTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            WEKE ++      KP L K + R  WK +  LGL  FFE  I + QP  +  ++S+    +      L    I +  L    ++L ++ + Y++  ++ GM+L++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L+M    + LA + VL+IL+P Q+ LGK +   R    + TD RI+ ++E+I+GM+++KMY WE  F +++  +R+K +         ++L +A  F  S+ I+        L+G  +S+  V++ V L + +R ++   F   +  A + +V+  RI+
Sbjct:   61 WEKELQKAQNEGRKPRLTKAIIRCHWKTFSVLGLFTFFEESIRVVQPIFLGNVISYFERYDANDSAVLANAYINAAALSACTLILAVVHHIYFYHLLRAGMKLRVAMCHMIYRKALRLSNTAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWMEIGPSCLAGMAVLIILMPLQLCLGKFFTSLRGKTAAFTDTRIRTMNEVISGMRIIKMYAWEQSFTELVNNIRKKEINKVLRSSYLRALNLASFFVASKIILFVTFTTYVLLGNVISASRVFVAVSLYSAVRLTVTLFFPSAVERASEAKVSIRRIK 384          

Query: 1234 DKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKS-------RTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEM----DKRNASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            D  + V  ++  A W++ + +   L+ +SF  +  +  A++G +G+GKSS+  A+LGELP + G +   G ++Y SQQPW+FSG++  NILF    +  ++E+ I A AL +D++++ +  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F  CI +   +K+ +LVTHQL  LK+   IL+L +G M+  GT+ E +  GVD  S+LK++  E     +       + TF+E +I+  +         ++R S K+      +P   G+ A N  +     SR E        +    Y  YF+ G S FF++ + +L       YV  D WLS W  +     + RNA+       D  + +G+   LT  T   G+   + +F I + + + LH +M  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DFI +  LV+  + +A+    W +I ++ L ++F  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRA+K++   ++ F   QD +S+A+FL++++SRWFA RLD +C +F++   +   +LV  K +N    GL L+Y + L+G+ QW+VRQS+EVEN M S+ER+ EY  L  E P   K+       WP  G I F NV+  Y      VLK++  +I+ REK+GIVGRTGAGKSSLIS LFRL E P   GKI +D+   + +GL  LR  +++IPQ+PVLF GT+R NLDPFNE TD ++   L+
Sbjct:  405 DGKAIVHVQDFTAFWDKALDSP-TLQGLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSTAPGTPTLRKRTFSEASIWSQQ---------SSRPSLKDG-----AP--EGQDAENTQAVQPEESRSE------GRIGFKAYKNYFSAGASWFFIIFLVLLNMVGQVFYVLQDWWLSHWANKQGALNNTRNANGNITETLDLSWYLGIYAGLTAVTVLFGIARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFVIVVAFG--SLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECKKRPPP--GWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSE-PE--GKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWRALE 1151          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + I  LP K+ + ++E GSN SVGQRQL+C+ARA+LK  ++++IDEATANVD  TD LIQ+ ++  FA CTVLTIAHRL+TI++SD+I+V+++G + ++D P++L  + P+S F ++VQQ G  E   L + A
Sbjct: 1155 LKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQN-PESLFYKMVQQLGKGEAAALTETA 1288          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W+KE     +   KPSL K + +  WK Y  LG+    E    + QP  + K++ +    +      L     Y+ +L +  ++L ++ + Y++     GMRL++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L++    + LA + VL+IL+P Q  +GKL+   R    + TD RI+ ++E+I GM+++KMY WE  F  +IA LR+K +         + + +A  F  ++ I+        L+G  +++  V++ + L   +R ++   F   I    +  V+  RI+
Sbjct:   64 WDKELLRAKKDSRKPSLTKAIIKCYWKSYLILGIFTLIEEGTRVVQPLFLGKIIEYFEKYDPDDSVALHTAYGYAAVLSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAIVSIRRIK 387          

Query: 1234 DKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKS-------RTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEM----DKRNASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            D  + V  ++  A W++ + +   L+ +SF  +  +  A++G +G+GKSS+  A+LGELP + G +   G ++Y SQQPW+FSG++  NILF    +  ++E+ I A AL +D++++ +  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F  CI +   +K+ +LVTHQL  LK+   IL+L +G M+  GT+ E +  GVD  S+LK++  E     +       + TF+E +I+  +         ++R S K+      +P   G+ A N  +     SR E        +    Y  YF+ G S FF++ + +L       YV  D WLS W  +     + RNA+       D  + +G+   LT  T   G+   + +F I + + + LH +M  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DFI +  LV+  + +A+    W +I ++ L ++F  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRA+K++   ++ F   QD +S+A+FL++++SRWFA RLD +C +F++   +   +LV  K +N    GL L+Y + L+G+ QW+VRQS+EVEN M S+ER+ EY  L  E P   K+       WP  G I F NV+  Y      VLK++  +I+ REK+GIVGRTGAGKSSLIS LFRL E P   GKI +D+   + +GL  LR  +++IPQ+PVLF GT+R NLDPFNE TD ++   L+
Sbjct:  330 DGKAIVHVQDFTAFWDKAL-DSPTLQGLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSTAPGTPTLRKRTFSEASIWSQQ---------SSRPSLKDG-----AP--EGQDAENTQAVQPEESRSE------GRIGFKAYKNYFSAGASWFFIIFLVLLNMVGQVFYVLQDWWLSHWANKQGALNNTRNANGNITETLDLSWYLGIYAGLTAVTVLFGIARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFVIVVAFG--SLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECKKRPPP--GWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSE-PE--GKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWRALE 1076          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + I  LP K+ + ++E GSN SVGQRQL+C+ARA+LK  ++++IDEATANVD  TD LIQ+ ++  FA CTVLTIAHRL+TI++SD+I+V+++G + ++D P++L  + P+S F ++VQQ G  E   L + A
Sbjct: 1080 LKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQN-PESLFYKMVQQLGKGEAAALTETA 1213          

Query:  386 KILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            + L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L++    + LA + VL+IL+P Q  +GKL+   R    + TD RI+ ++E+I GM+++KMY WE  F  +IA LR+K +         + + +A  F  ++ I+        L+G  +++  V++ + L   +R ++   F   I    +  V+  RI+
Sbjct:  102 EALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAIVSIRRIK 312          

Query: 1246 SVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKN-NQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEII-SQGV---DVHSILKQDTTE--YVIDKSRTTFNEDAIYVSEITE--DRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDEL---------------EQFSHDNVKLNLYWKYF-TVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAG-GLLSVICLF---LICIYSC----KALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            +V F      W+ ++  E  ++D++  +K  Q  A++G +GSGKSS+  A+LGE+    GHI   GS++Y  QQ WI +G+I  NILF    +  ++++ I A AL  D+E++P   +  +GE+G+ LSGGQK R+SLARA Y  ADI +LDDPL+AVD  VG  IF + +    L   K  +LVTH +H L  VD+I+VL +G ++  G++++++  +GV   +  + +K    E    +D      + D   +  + E  D A +L  R  +  +     S         ++ S+  + S + L               E      VK ++Y KY   VG  +   +++F  Y      ++ T++WLS WT++ +K+N +D    + D         + +  F   G+   I L    L  IY+C    K LH ++L +IL +P+ FF+    GRI+NRF+ DIS  DD LP TL+ ++L    ++  L +        IIII+ L I++ +++  Y+  S  ++RL++VT+SP+++H S T+ GL  IRAF+ Q  F    +K+ D   K  F +I+S+RW A RL+ V  + +  +  + + ++Y   +     G VL+  + +     W VR +SEVE  + ++ERI EYI +  E P +T +      DWP  G I+F N  + Y      VLK +   I+  EK+G+VGRTGAGKSSL + LFR++E     G+II+D  DI+++GL  LR  + +IPQDP+LF G +R NLDPFN+++D ++   L+
Sbjct:  634 AVQFSEASFTWDRDL--EATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIF--YVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRD---------MRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCS--ALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKPPA--DWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILE--SAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALE 1409          

Query: 3576 VSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSD 3860
            V+EGG NLS+GQRQL+C+ RA+L+++K++V+DEATA VDL TDSLIQ T+++ F+ CTV+TIAHRL TIM+SD+I+V+++G + ++  P  L S+
Sbjct: 1428 VTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSN 1522          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL 778
            Y+     +GM ++  I A VY+K L L+  A  Q T G+ +NLMS D  K      ++H +W   L    +   L+   RE G   LA + ++++L+P    L     K +   +   D+R+K+++E+++G++++K + WEP F + +  +R+K L
Sbjct:  379 YFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLW---RELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKEL 531          

Query: 1393 ALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSI----LKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN----------DKPF---------LIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLI 3549
            A+LG++ L +G I  +G+ +Y +QQ WI + ++  NILF       ++   + +  L  D+ I+PN  LT +GERG  LSGGQ+ RISLARA Y    I +LDDPL+A+DA VG+ IF   I +  K K VL VTHQL  L   D+++ + EG +   GT  E+++   D  +I    L  +T    I+  +          S+ ++D+     +    K          +  E    V          ++E+    +V  ++YW Y          +++ +L+   +    F+  WLS+W     K+ + ++  Y+           D PF         L   ++L L    G     +      + +   LH+++   IL SP+KFF+    GRILNRFSKD+   D  LP   + FI +  LV F +G+ +    W ++ +  LLI+F  L      +   +KRL+ +T+SP  +HI++++QGL TI A+  +  F   +Q+  D     FFL+  + RW A RLD +    I T     + ++ H +I ++  GL ++Y V L GL Q+ VR +SE E + TS+ERI  YI  L  E P   K   +   DWP  G + F+N  + Y      VLK V+  I+ +EKIGIVGRTG+GKSSL   LFRLVE+   C KI  D   IS +GL  LR+ +A+IPQ+PVLF GT+R+NLDPFN++T+  +   L+ +   + I
Sbjct:  607 AILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEINSKKEATG------SQKSQDKGPKPGSVKKEK---------AVKSEEGQLV----------QVEEKGQGSVPWSVYWVYIQAAGGPLAFLVIMVLFMLNVGSTAFSTWWLSYWI----KQGSGNSTVYQGNRSFVSDSMKDNPFMQYYASIYALSMAVMLILKAIRG-----VVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSLLHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKRQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTT--GLMIVLMHGQIPSAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKN-KAPPHDWPQEGEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKI--DGIRISDIGLADLRSKLAIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECI 1311          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSD 3860
            + + I +LP KL S V E G N SVG+RQL+C+ARALL+  K++++DEATA +D  TD LIQ+T++  FA CT+LTIAHRL T++ SDRI+V+  G V +FD P +L S+
Sbjct: 1307 MKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSN 1416          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHT-----DSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNG-IVDQFDHPHLLFSDRPDSTFIQ--LVQQTGPAE 3911
            LP+   + + E G+NLS GQRQ I +ARAL     + ++D+  + +D H      +S I+K L+S     TVL + H+L  +++ D +I +  G I ++  H  L+  +   +T     L+ +T P E
Sbjct:  670 LPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSK----TVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVE 793          

Query: 3049 RQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT 3528
            RQ    E+Q    E+    +    E P   +E   Q+     TG +  Q             L N++L IE+ + +GI G  G+GK+SL+S +          G++ +    I+  G      + A + Q   +   T+R N+    EF +    +VL +
Sbjct:  531 RQLQHTEHQAVLAEQKGHLLLDSDERPSPEEEEGKQI----HTGSLRLQRT-----------LYNIDLEIEEGKLVGICGSVGSGKTSLVSAIL---------GQMTLLEGSIAVSG------TFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNS 660          

Query: 1210 SKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTG-------------SLSYTSQQPWIFSGSILQNI-LFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIIS 1887
            +K  P D  +   VTFEN   ++ EN+    +LK +SF++K  +   I+G  GSGKSS+ MAL   + LS G I   G              L+   Q+P +FSG++  N+  FN    +Q    +  T +   I  +P +L + V E G   S G++  + +AR A L    IL+ D   A        +  + I E F D  +L + H+LH +   D+I+VL +G ++ F T + ++S
Sbjct: 1179 NKAPPHDWPQEGEVTFENAEMRYRENLP--LVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGIRISDIGLADLRSKLAIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIAR-ALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLS 1415          

Query: 1393 ALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSI----LKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN----------DKPF---------LIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLI 3549
            A+LG++ L +G I  +G+ +Y +QQ WI + ++  NILF       ++   + +  L  D+ I+PN  LT +GERG  LSGGQ+ RISLARA Y    I +LDDPL+A+DA VG+ IF   I +  K K VL VTHQL  L   D+++ + EG +   GT  E+++   D  +I    L  +T    I+  +          S+ ++D+     +    K          +  E    V          ++E+    +V  ++YW Y          +++ +L+   +    F+  WLS+W     K+ + ++  Y+           D PF         L   ++L L    G     +      + +   LH+++   IL SP+KFF+    GRILNRFSKD+   D  LP   + FI +  LV F +G+ +    W ++ +  LLI+F  L      +   +KRL+ +T+SP  +HI++++QGL TI A+  +  F   +Q+  D     FFL+  + RW A RLD +    I T     + ++ H +I ++  GL ++Y V L GL Q+ VR +SE E + TS+ERI  YI  L  E P   K   +   DWP  G + F+N  + Y      VLK V+  I+ +EKIGIVGRTG+GKSSL   LFRLVE+   C KI  D   IS +GL  LR+ +A+IPQ+PVLF GT+R+NLDPFN++T+  +   L+ +   + I
Sbjct:  607 AILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEINSKKEATG------SQKSQDKGPKPGSVKKEK---------AVKSEEGQLV----------QVEEKGQGSVPWSVYWVYIQAAGGPLAFLVIMVLFMLNVGSTAFSTWWLSYWI----KQGSGNSTVYQGNRSFVSDSMKDNPFMQYYASIYALSMAVMLILKAIRG-----VVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSLLHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKRQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTT--GLMIVLMHGQIPSAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKN-KAPPHDWPQEGEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKI--DGIRISDIGLADLRSKLAIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECI 1311          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSD 3860
            + + I +LP KL S V E G N SVG+RQL+C+ARALL+  K++++DEATA +D  TD LIQ+T++  FA CT+LTIAHRL T++ SDRI+V+  G V +FD P +L S+
Sbjct: 1307 MKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSN 1416          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHT-----DSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNG-IVDQFDHPHLLFSDRPDSTFIQ--LVQQTGPAE 3911
            LP+   + + E G+NLS GQRQ I +ARAL     + ++D+  + +D H      +S I+K L+S     TVL + H+L  +++ D +I +  G I ++  H  L+  +   +T     L+ +T P E
Sbjct:  670 LPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSK----TVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVE 793          

Query: 3049 RQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT 3528
            RQ    E+Q    E+    +    E P   +E   Q+     TG +  Q             L N++L IE+ + +GI G  G+GK+SL+S +          G++ +    I+  G      + A + Q   +   T+R N+    EF +    +VL +
Sbjct:  531 RQLQHTEHQAVLAEQKGHLLLDSDERPSPEEEEGKQI----HTGSLRLQRT-----------LYNIDLEIEEGKLVGICGSVGSGKTSLVSAIL---------GQMTLLEGSIAVSG------TFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNS 660          

Query: 1210 SKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTG-------------SLSYTSQQPWIFSGSILQNI-LFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIIS 1887
            +K  P D  +   VTFEN   ++ EN+    +LK +SF++K  +   I+G  GSGKSS+ MAL   + LS G I   G              L+   Q+P +FSG++  N+  FN    +Q    +  T +   I  +P +L + V E G   S G++  + +AR A L    IL+ D   A        +  + I E F D  +L + H+LH +   D+I+VL +G ++ F T + ++S
Sbjct: 1179 NKAPPHDWPQEGEVTFENAEMRYRENLP--LVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGIRISDIGLADLRSKLAIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIAR-ALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLS 1415          

Query: 1177 MNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMD----KRNASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++EIS      ++ LP D  K   V  ++  A W++  +    L+ +SF+++  +  A++G +G+GKSS+  A+LGEL  S G +   G ++Y SQQPW+FSG++  NILF    +  ++E+ I A AL +D++++ +  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F  CI ++  +K+ +LVTHQL  LK+  +IL+L +G M+  GT+ E +  G+D  S+LK+D  E           +  +  +    +R  + ++  S +     L    +  +   NV    +  +R E        V    Y  YF  G      + + +L       YV  D WLS+W  +        N       K D  + +G+   LT++T   G+   + +F + + S + LH KM  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DFI +   V+  + +A     W  I ++ L IIF  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRA+K++   ++ F   QD +S+A+FL++++SRWFA RLD +C +F++   +   +L+  K ++    GL L+Y + L+G+ QW VRQS+EVEN M S+ER+ EY  L  E P   ++       WP  G I F NV+  Y      VLK++  +I+ +EK+GIVGRTGAGKSSLIS LFRL E P   GKI +D+   + +GL  LR  +++IPQ+PVLF GT+R NLDPFNE TD ++   LQ
Sbjct:  392 LDEISQR----NRQLPSDGKKMVHV--QDFTAFWDK-ASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEES---------EQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSE------GKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFG--SLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPP--AWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSE-PE--GKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQ 1151          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L +TI  LP K+ + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQK ++  FAHCTVLTIAHRL+TI++SD+I+V+++G + ++D P++L  ++ +S F ++VQQ G
Sbjct: 1155 LKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNK-ESLFYKMVQQLG 1277          

Query:   74 WEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQV 1021
            W+KE  R      KPSL + + +  WK Y  LG+    E    + QP  + K++++    +      L     Y+T+L    ++L ++ + Y++     GMRL++ +  ++Y K L+L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A T +L+M    + LA + VL+IL+P Q   GKL+   R    + TD RI+ ++E+I G++++KMY WE  F  +I  LR+K +         + + +A  FS S+ I+        L+G  +++  V++ V L   +R ++   F   I    +  V+  RIQ 
Sbjct:   64 WDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQT 388          

Query: 1246 SVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKN-NQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEII-SQGV---DVHSILKQDTTE---YVIDKSRTTFNEDAIY--VSEITEDRATNLNNRNSSKEQTVPLLSPVIT--GETASNVSSACNLSSRDELEQ------------FSHDNVKLNLYWKYF-TVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAG-GLLSVICLF---LICIYSC----KALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDF-GLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            +V F      W+ ++  E  ++D++  +K  Q  A++G +GSGKSS+  A+LGE+    GHI   GS +Y  QQ WI +G+I  NILF    N  +++Q + A AL  D+EI+P   +  +GE+G+ LSGGQK R+SLARAAY  ADI +LDDPL+AVDA VG  IF + +    L   K  + VTH +H L  VD+I+VL +G ++  G++ +++  +GV   +  + +K    E    V + S    ++D +   + EI ED A+    R +S  +T+   S   +  G++  N     N++   E E+                 VK ++Y KY   VG  +   +++F  Y      ++ +++WLS WT++ D  N ++      D         + +  F   GL   ICL    L  IY+C    KALH ++L +IL +P++FF+    GRI+NRFS DIS  DDLLP TL+ +++    +   L +         III+ L I++ +++  Y+  S  ++RL++VT+SP+++H S T+ GL  IRAF+ Q  F    +K+ D   K  F +I+S+RW A RL+ V  + +     S + LV ++K  T D  G VL+  + +     W VR +SE E  + ++ERI EYI +  E P +T +      DWP  G I+F N  + Y      VLK +   I+  EK+G+VGRTGAGKSSL + LFR++E     G+II+D  D++++GL  LR  + +IPQDP+LF G++R NLDPFN+++D +V   L+
Sbjct:  632 AVKFSEASFTWDPDL--EATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFMKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILF--YGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRD---------MRIGVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFC---SALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDKRPPA--DWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILE--SAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALE 1407          

Query: 3564 LYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L S V+EGG NLS+GQRQL+C+ RA+L+++K++V+DEATA VDL TDSLIQ T++  F+ CTV+TIAHRL TIM+SD+I+V++NG + ++  P  L S+R   +F  + ++ G
Sbjct: 1422 LLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNR--GSFYLMAKEAG 1532          

Query:  341 MGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTL 778
            +GM ++  + + +Y+K L L+  A  Q T G+ +NLMS D  K   +  ++  +W      +  T+ ++   RE G   LA + V+++LIP    L       +   +   D+R+K+++E+++G++++K + WEP F + +  +R+K L
Sbjct:  384 LGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSS---VIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKEL 529          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDK-SRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNAS-----DAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKK-INTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVL 3522
            + V  +N    WN+   + + LK+I+F  K      ++G +GSGKS++  A+LGEL    G I   GS++Y  QQ WI + ++ +NI+F    + + +++ +   AL RDIE+ P      +GERG+ LSGGQK R+S+ARA Y  AD+ +LDDPL+AVD+ VG  +F +C   +   K V+LV +Q++ L   D  +VL  G ++  GT+ E+I+  ++  S+L+    EY +D+ ++   ++D     +  +        + S K+ T                     L S +E EQ +   V   +YWKY T G    F+  M IL+        FTD WLS W TE  +R  S     +     +D+   I  I + +++    ++     F   + +  ++H ++ +++L  P+ FF++   GRI+NRF++D+ I D+L+  ++  F      VL  L L S    W +I +  + I+F+ L+  Y   S  ++R+EA+TRSP+F H S TL G+ +IRA+K Q     + QK+ D  +  +    + +RW   RLD +  + +    +SC+ +   K  I+ SD GLVL+Y + +       V Q+++ E +M S+ERI +YI    E P++  +      DWP  G I+F N+ + Y      VLK +   I+ +EKIGIVGRTGAGKSS++  LFRL+E     G I +D ++I+  GLK LR ++A+IPQDPVLF GT+R NLDPFNE  D ++ ++L
Sbjct:  426 NGVYMKNSTTTWNKEKEDSFGLKNINFEAKGQSLTMVVGSVGSGKSTLVQAMLGELETIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQINYLPFADNTVVLKSGEIVERGTYYELINAKLEFASLLQ----EYGVDENTKGDDSDDDDDKKDDDKKEEKVEKPKQSDKDGT---------------------LISEEEAEQGA---VAGKVYWKYVTAGGGLLFLFAM-ILFLLETGSKTFTDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGI-YIGVGMASIIVTVVRTFSFFEYAVRAAHSIHHELFNALLKKPMSFFDQTPLGRIINRFTRDLDIIDNLIATSIAQFFTLMLSVLATLILISIIVPWLLIPLAPICILFFILQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILKNQKRLDDNNNCYLTLQAMNRWLGLRLDFLGNLIV---FFSCIFITLKKDTISPSDVGLVLSYALSITSNLNQGVLQAADTETKMNSVERISQYIRGAVEAPQIIDDCRPS-PDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASE--GSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNECPDHELWSIL 1157          

Query: 3558 DKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            + L S V+E G N SVGQRQLI +ARALL++ K++V+DEATA+VD  +DSLIQ T+++ F++CT+LTIAHRL+TIM+SD+I+V++ G + +FD P  L  ++ +     LV +TGP     LRK+A
Sbjct: 1171 EGLNSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDKIMVLDAGKISEFDEPWTLLQNQ-NGLLTWLVNETGPQNAIYLRKLA 1295          

Query:  329 LTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKT--LLYGFVR 796
            +T++ G RL+  I   VY+K +KL+  A   T+ GQI+NL+S+D  +    ++    +  G        + L +   + G      + ++L  IP      K   + R +++  TD R+K+ SE++  M+++K+Y WE  F K +   R     LL+ F R
Sbjct:  177 VTVRTGDRLRSIIVLDVYKKAIKLSNSARSNTSPGQIVNLISNDAQRM---IEVFGILNNGLFALPQIIICLALLYEKIGWPTFVGLGLMLAAIPFNGLAAKKLTETRRILIGHTDGRVKVTSEILQAMKIIKLYAWEDSFAKKVLDRRNNEIKLLFSFTR 334          

Query: 1243 SSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSIL-KQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLM--FILYATTMTLYVFTDIWLSWWTTEMDKRNAS-----DAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLI---CIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKK-INTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            + V  +N    WN+   + + LK+I+F         ++G +GSGKS++  A+LGEL +  G I   GS++Y  QQ WI + ++ +NI+F    + + +++ +   AL RDIE+ P      +GERG+ LSGGQK R+S+ARA Y  AD+ +LDDPL+AVD+ VG  +F +C   +   K V+LV +QL+ L   D  +VL  G ++  GT+ E+I+  ++  SIL K    E VI K +   +ED     +  E    +LN    S+ ++            +SN      L S +E EQ +   V   +YWKY T G    F+V M  F+L   + T   F+D WLS W TE  +R  S     +     +D+   I + L   + F    +SV   F+     +Y+ +A+H ++ +++L  P+ FF++   GRI+NRF++D+   D+L+  ++  F+     V+  + L S    + +I +  + IIF+ L+  Y   S  ++R+EA+TRSP+F H S TL G+ +IRA+K Q       QK+ D  +  +    + +RW   RLD +  +      ++C+ +   K  I+ ++ GL L Y + L G   +A  Q+++ E +M S+ERI +YI    E P++  +      DWP  G I+F N+ + Y      VLK +   I+ +EKIGIVGRTGAGKSS++  LFRL+E     G I +D ++I+  GLK LR ++A+IPQDPVLF GT+R NLDPFNE ++ D+ + ++
Sbjct:  421 NGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCFKGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSILEKYGVDENVISK-KDDIDEDEDEDQDTIEKVEIDLNKDEKSQPKS-----------KSSNTDGT--LISEEESEQGA---VAGKVYWKYVTAGGGLLFLVSMIFFLLETGSKT---FSDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGLGMAAVF----ISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQKRLDDNNNCYLTLQAMNRWLGLRLDFLANLI---TFFACIFITIDKDTISPANVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIIDDCRPSP-DWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASE--GSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIE 1164          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            +  L   L S V+E G N SVGQRQLI +ARALL++ K++V+DEATA+VD  +DSLIQ T+++ F++CT+LTIAHRL+TIM+SDRI+V++ G + +FD P  L  ++ +     LV +TGP     LRK+A
Sbjct: 1172 VKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQ-NGLLTWLVDETGPQNAIYLRKLA 1301          

Query:  329 LTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKT--LLYGFVR 796
            ++ + G RL+  I   VY+K +KL+  A   T+ GQI+NLMS+D  +    ++       G L      + L +  ++ G      + ++L  IP      K   + R  ++S++D R+K  +E++  ++++K+Y WE  F K + + R     LL+ + R
Sbjct:  172 ISFRTGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRM---VEVFGMFNNGALALPQIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSR 329          

Query: 1276 WNENMTNE-YILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNN-QFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYK----NDKPFL---IGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAF--KSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKK-INTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            WN+    E + LK+I+F  K      I+G +GSGKSS+  A+LGE+ +  G +   G+++Y  QQ WI + ++  NILF  P +  ++ + +   AL+RDIE+ P   L  +GERGV LSGGQK R+S+ARA Y  +D+ +LDDPL+AVDA VG  +F +C   + K K V+L  +QL+ L      +VL  G +   G++ ++I+   +   +L+     Y +D+S    NED      + +D+    ++    +E+T P   P +  +          L+S++E E+ +   V + +YWKY TVG   F  ++ FI +        F D WLS W  E  K   + A+  +     D  +L   IG+ + ++   AG        F   + + +ALH ++ +++L +P+ FF+    GRI+NRF++D+   D+L+  ++  F++    V+  L + S    + ++ +  + IIF+ L+  Y   S  ++RLEA++RSP+F+H S TL G+ +IRA+  K +N    +F  + D  +K +    + ++W   RLD +  +      ++C+ +   +  I+ ++ GL L+Y + L G    A  Q+++ E +M S+ERI  YI  P E  ++ ++      DWP  G I F N+ + Y      VLK ++  I+ +EKIGIVGRTGAGKSS++  LFRL+E     G I++D ++I+  GLK LR ++A+IPQDPVLF GT+R N+DPFNE TD  + +VL+
Sbjct:  446 WNQEKKEESFTLKNINFEAKGKTLTMIVGSVGSGKSSLIQAMLGEMDVLDGSVAMKGNVAYVPQQAWIINATLKDNILFGSPYDEAKYRKVLEVCALERDIELFPQGDLVEIGERGVNLSGGQKQRVSIARAVYSDSDVYILDDPLSAVDAHVGKHLFHRCFKGILKSKTVILAANQLNYLPFAHNTVVLKAGEISERGSYQQLINAQKEFSGLLQA----YGVDES--AVNED------VEDDKEIEESDNIVVEEKTKPTEKPKLQNKDGV-------LTSQEEREEGA---VAMWVYWKYITVG-GGFLFLMAFIFFLMDTGTRTFVDWWLSHWQNESTKNALAVAQGLEPSGLTDTQYLGIYIGVGMTSILISAG---RNFLFFEYTVRASRALHHQLFNALLRAPMSFFDTTPLGRIINRFTRDLDGVDNLMATSISQFLVFFTTVVATLIIISIITPFLLVPLAPICIIFYFLQFFYRYTSRELQRLEAISRSPIFSHFSETLGGVVSIRAYRKKEENILTNQF--RLDNNNKCYLTLQAMNQWLGLRLDLLANL---VTFFACLFITIDRDTISAANVGLSLSYALSLTGNLNRATLQAADTETKMNSVERITHYIKGPVEALQIVED-HRPAPDWPPHGAITFDNLVMRYREGLDPVLKGISCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASE--GAILIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENIDPFNEKTDDQLWSVLK 1173          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L D    L   L S V+E G N SVGQRQL+C+ARALL+  K++V+DEATA+VD H+DSLIQ T++  F++CT+LTIAHRL+TIM+SDRIIV++ G + +FD P  L  + P      LV++TGP     LR++A
Sbjct: 1177 LHDVAKSLEGGLDSKVTENGDNWSVGQRQLLCLARALLRDPKILVLDEATASVDGHSDSLIQATIREKFSNCTILTIAHRLNTIMDSDRIIVLDAGKISEFDEPWTLLQN-PAGLLNWLVEETGPQNAAYLRRLA 1310          

Query:  329 LTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAG---LASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKT--LLYGFVR 796
            ++ + G RL+  I   VY K +KL+  A   T+ G+I+NLMS+D  +    ++    +  G        V L +  R  G      + ++L  +P      K   + R  ++  TD+R+K  +E++  ++++K+Y WE  F K + + R     LL+ F R
Sbjct:  186 ISARTGDRLRSVIVLDVYRKAIKLSNSARANTSPGEIVNLMSNDAQRM---VEVFQLVNNGVFALPQIIVCLALLYRAIGWPTFVGLGLMLAAVPFNGIAAKKLTEIRRHLVGFTDKRVKTTNEILQAIKIIKLYAWEDSFAKKVIERREAEIKLLFSFSR 343          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL +P++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ESRSEGNIGIRMYWKYFRAGANVVMLVLLVLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAETLHNRMFNSILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL +P++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ELRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAETLHNRMFNSILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL +P++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ELRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAEMLHNRMFNSILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRN-----------ASDAEFYKNDKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            ++FL L E   N +         PL  +  K  SV  +++   W++ + +   L+++ F++K  Q  A+IG +G+GKSS+   +LGELP  KG I   G L+Y SQQPW+F G+I  NILF      Q +E+ + A AL RD+E++P+  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA V   +F QC+  + KDK  +LVTHQL  LK+ ++ILVL EG+M+A G+++E+   G+D  S+LK+D  E    +                     +  +R  S+       S V++ +  S+   A  + +  E E  S  N+ + +YWKYF  G +   +VL+ +L     T Y+  D WLS+W TE +K +           ++     + D  F +G+   LT +T   G +  + +F   + S + LH +M +SIL + ++FF+ N  GRILNRFSKDI   D LLP T  DFI     ++  + +AS    W +I +L LLI F  LRR ++  S  +KR+E+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C+VF+    + C  L+    +N  D GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++  S   DWP+ G I F  V+  Y      VLKN++ M   REK+GIVGRTGAGKSSLIS LFRL E P   GKI+VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D D+   L+
Sbjct:  387 KKFLLLDELVKNHL---------PLSQEEKKEPSVEMQDLICYWDKTL-DAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSGLDFTSLLKKDEEEESGSEKGEA---------------PRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEPVHTMAE-ESRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAETLHNRMFNSILRTQVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGC--LLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQKRPSP--DWPNRGLITFDRVNFSYSSDGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSE-PE--GKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALE 1159          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ +V++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  ++    F ++VQQTG AE   L + A
Sbjct: 1163 LKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQ-SGIFYKMVQQTGKAEATSLLQTA 1296          

Query:   59 EYLSEWEKEQRR-----NKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E+ +       P L K + R  WK Y  LG+    E  I + QP  + KL+ +           L+E   Y+T + ++ + L L+ + Y++   + GM+++I +  ++Y K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+ L+P Q   GKL+ K+R    ++TD RI+ ++E+++G++++KMY WE  F  ++  +RRK +         + L +A  F+ ++ I+        LVG  +S+  V++ V L + +R ++   F   I    +  ++  RI+
Sbjct:   59 ELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIK 387          

Query: 1276 WNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDK----RNASDAEFYKN---DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNY-WSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            W++++     L++ISF+++  +  A+IG +G+GKSS+  A+LGELP  KG I  TG ++Y SQQPW+FSG++  NILF+   +  ++E  +   AL +D+E++ N  LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F +CI E    K+ +LVTHQL  L++ ++IL+L +G M+  GT+ E +  G+D  S+LK+D  E V+++       +       T   ++ L+  +S   Q        +      N  +A    SR+E        +   LY KYF+ G + F + ++ +        YV  D WLS+W     K    RN ++   YKN   D  F +G+   LT++T   G++  + +F + + S + LH +M  SIL +P+ FF+ N  GRILNRFSKDI   DDLLP+T  DF + T L +FG+   +     W +I ++ L I+F  LRR +++ S  IKRLE+ TRSP+F+H+S++LQGL TIRA K++  F+K F   QD +S+A+FL++++SRWFA RLD +C VF++   +   +L+  K +N    GL L+Y + L+G  QW VRQS+EVEN M S+ER+ EY  L  E P  T +      +WP+ G I F+NV+  Y      VL++++++I+ +EK+GIVGRTGAGKSSLI+ LFRL E P   G+I +D+   S LGL  LR  I++IPQ+PVLF GT+R NLDPFNE+TD ++   L+
Sbjct:  374 WDKSLETP-ALQNISFTVRRGELLAVIGPVGAGKSSLLSAVLGELPKDKGVINVTGRIAYVSQQPWVFSGTVRSNILFDKEYEKEKYENVLKVCALKKDLELLANGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEKCICEALHQKICVLVTHQLQYLRAANQILILKDGKMVGKGTYAEFLRSGIDFASLLKKD--EEVVEQQSVPGTPNLKSARNRTFSESSVLSQDSSIHSQK----DGAVEQPPGENALAAVPEESRNE------GKINFKLYRKYFSAGANYFVIFILLVFNILAQVAYVLQDWWLSYWANHQQKLNLTRNGNNGT-YKNEHLDLNFYLGIYAGLTVATILFGIIRSLLMFQVLVNSGQNLHNRMFQSILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDF-MQTLLQIFGVVAVAVAVIPWILIPLIPLFILFIFLRRYFLDTSRDIKRLESTTRSPVFSHLSSSLQGLWTIRALKAEERFQKLFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFG--SLLLAKTLNAGQVGLALSYAITLMGTFQWGVRQSAEVENLMISVERVMEYTELEKEAPWETNKHPPP--EWPNQGMIAFENVNFTYSLDGPLVLRHLSVLIKPKEKVGIVGRTGAGKSSLIAALFRLAE-PE--GRIWIDKYLTSELGLHDLRKKISIIPQEPVLFTGTMRKNLDPFNEYTDEELWNALE 1111          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L + +  LPDK+ + ++E GSN SVGQRQL+C+ARA+LK+ ++++IDEATANVD  TD  IQKT++ TFAHCTVLTIAHRL+TI++SDRI+V++ G + ++  P++L  ++ DS F ++VQQ G AE   L + A
Sbjct: 1115 LKEVVEDLPDKMETQLAESGSNFSVGQRQLVCLARAVLKKNRILIIDEATANVDPRTDEFIQKTIRETFAHCTVLTIAHRLNTIIDSDRIMVLDAGRLKEYGEPYILLQEQ-DSLFYKMVQQVGKAEAASLIETA 1248          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN-ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W+KE     +R   P L K +    WK Y   G+    E  + + QP  +  ++SF    +  +L     Y+  L V  ++L ++ + Y++   + GM+L++ +  ++Y K L+L+  A+ +TT+GQI+NL+S+D++KF+    FLHF+W GPL  +A TV+L++    + LA + VL+IL+P Q  +G+L+   R    ++TD RI+ ++E+I+GM+++KMY WE  F +++  LRRK +         + L +A  F  S+  +        L+G  +S+  V++ V L   +R ++   F   +    +  ++  RI+
Sbjct:   21 WDKEVQKAKKRGKTPHLTKAIILCYWKSYLVFGIYTMIEETLKIVQPIFLGNIISFFENYDASSLNVAYCYAGALSVCTLILAIMHHLYFYHVQRAGMKLRVAMCHMIYRKALRLSNAAMAKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVKIGPSCLAGMAVLIILLPVQTCIGRLFSSLRSKTAALTDVRIRTMNEVISGMKIIKMYAWEKSFAELVNGLRRKEIAMVMKSSYLRGLNLASFFVASKITVFMTFMAYVLLGNTMSASKVFVAVSLYGAVRLTVTLFFPSAVERVSESLISIRRIK 341          

Query: 1210 SKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGE--TASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-----DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            S PL  +  K +SV   ++   W++++ +   L+++SF++K     A+IG +G+GKSS+   +LGELP  KG +   G L+Y SQQP +F G+I  NILF      Q +E+ + A AL RD+E++P   LT +G+RG  LSGGQKAR++LARA Y  ADI LLDDPL+AVDA VG  +F QCI  + K K  +LVTHQL  LK+ D ILVL EG+M+A GT++E++  GVD  S+LK+D              E+   V  +   R   L+ +NS + +T  L+S    GE   A  V +          E  S  N+   +Y +YFT G S   ++ + +L     T Y+  D WL++W +E +K ++ +              F +G+   LT++T   G +  + +F   + S + LH +M + IL +P++FF+ N  GRILNRFSKDI   D  LP T  DFI     ++  + +A+    W +I +L LLI+F  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C++F+    + C  L+  + +     GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L  E P  T+       +WP+ G I F  V+  Y      VLKN++ MI  +EK+GIVGRTGAGKSSLIS LFRL E P   GKI VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D  +   L+
Sbjct:  399 SVPLLQEEKKEASVEIHDLICYWDKSL-DAPTLQNVSFTVKPGMLLAVIGPVGAGKSSLLSTILGELPQDKGVVKVRGDLTYASQQPCVFPGTIRSNILFGKELQPQRYEKVLRACALKRDMELLPEGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFEQCICGVLKKKPRILVTHQLQYLKAADHILVLKEGHMVARGTYSELLRSGVDFASLLKKDE------------EEEQQTVGTVISSRTRTLS-QNSVRSRTSSLMSEKDDGEQLPAEPVQTLAE-------ETRSEGNIGFGMYLRYFTAGISVLVLLGLVLLNLLAQTAYILQDWWLAYWASEQEKLDSMNITVNHTVTEELSLDFYLGIYAGLTVATLIFGFMRSLLMFNAMVRSAQTLHNRMFNCILRTPVRFFDVNPIGRILNRFSKDIGQVDSSLPWTFVDFIQVFLQIIGVIAVAASVIPWILIPVLPLLIVFLFLRRYFLQTSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSIFVTITAFGC--LLLRQNLEAGAVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVMEYTELENEAPWETQVRPPP--EWPNKGLITFDQVNFSYSSDGPVVLKNMSAMIRPKEKVGIVGRTGAGKSSLISALFRLAE-PE--GKIYVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDEALWNALE 1151          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  + P+  F ++VQQTG AE   L+++A
Sbjct: 1159 VEELPSKLETVLAESGSNFSVGQRQLVCLARAVLRKNRILIIDEATANVDPRTDELIQKTIREKFQECTVLTIAHRLNTIIDSDRILVLDAGQIHEYDEPHVLLQN-PEGIFYKMVQQTGKAEAASLKQLA 1288          

Query:   59 EYLSEWEKE-QRRNK----PSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E Q   K    P L K + R  WK Y  LG+    E  I L QP  + KL+ +    +      L E   Y+  +    + L L+ + Y++   + GM+++I +  ++Y+K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+IL+P Q   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  ++  +R+K +         + L +A  FS S+ I+        LVG  +S+  V++ V L + +R ++   F   I    +  V+ +RI+
Sbjct:   59 ELQSYWDQEVQSATKELRTPKLTKAIIRCYWKSYSILGVFTLIEELIKLVQPVFLGKLIRYFENYDPDDMAALYEAYGYAAGVSCCTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYKKALCLSSVAMGQTTTGQIVNLLSNDVNKFDEVTIFLHFLWVGPLQAAAVIGLLWQEIGASCLAGMAVLVILMPLQTVFGRLFSKFRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAALVNDVRKKEISKIMSSSYLRGLNMASFFSASKIIVFVTFAVYVLVGNKMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSEAGVSITRIK 387          

Query: 1210 SKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPN-ELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGE--TASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            S PL  +  K +SV   ++   W++++ +   L+++SF++K     A+IG +G+GKSS+   +LGELP  KG +   G L+Y SQQP +F G+I  NILF      Q +E+ + A AL R + + P+ +++T           G+KA I LA   Y  ADI LLDDPL+AVDA VG  +F QCI  + K K  +LVTHQL  LK+ D ILVL EG+M+A GT++E++  GVD  S+LK+D              E+   V  +   R   L+ +NS + +T  L+S    GE   A  V +          E  S  N+   +Y +YFT G S   +                           +     +    Y     FL     LT++T   G +  + +F   + S + LH +M + IL +P++FF+ N  GRILNRFSKDI   D  LP T  DFI  + +      +A+    W +I +L LLI+F  LRR ++  S  +KRLE+ TRSP+F+H+S++LQGL TIRAFK++  F++ F   QD +S+A+FL++++SRWFA RLD +C++F+    + C  L+  + +     GL L+Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L  E P  T+       +WP+ G I F  V+  Y      VLKN++ MI  +EK+GIVGRTGAGKSSLIS LFRL E P   GKI VD    S +GL  LR  +++IPQDPVLF GT+R NLDPFN+ +D  +   L+
Sbjct:  399 SVPLLQEEKKEASVEIHDLICYWDKSL-DAPTLQNVSFTVKPGMLLAVIGPVGAGKSSLLSTILGELPQDKGVVKVRGDLTYASQQPCVFPGTIRSNILFGKELQPQRYEKVLRACALKR-VRLFPDCKIIT-----------GKKALIQLA--VYQDADIYLLDDPLSAVDAEVGRHLFEQCICGVLKKKPRILVTHQLQYLKAADHILVLKEGHMVARGTYSELLRSGVDFASLLKKDE------------EEEQQTVGTVISSRTRTLS-QNSVRSRTSSLMSEKDDGEQLPAEPVQTLAE-------ETRSEGNIGFGMYLRYFTAGISVLVL------------------------LGLVLLNLLAQVHSYNTFNLFLSSG--LTVATLIFGFMRSLLMFNAMVRSAQTLHNRMFNCILRTPVRFFDVNPIGRILNRFSKDIGQVDSSLPWTFVDFIQVSVI-----AVAASVIPWILIPVLPLLIVFLFLRRYFLQTSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSIFVTITAFGC--LLLRQNLEAGAVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVMEYTELENEAPWETQVRPPP--EWPNKGLITFDQVNFSYSSDGPVVLKNMSAMIRPKEKVGIVGRTGAGKSSLISALFRLAE-PE--GKIYVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDEALWNALE 1101          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G + ++D PH+L  + P+  F ++VQQTG AE   L+++A
Sbjct: 1109 VEELPSKLETVLAESGSNFSVGQRQLVCLARAVLRKNRILIIDEATANVDPRTDELIQKTIREKFQECTVLTIAHRLNTIIDSDRILVLDAGQIHEYDEPHVLLQN-PEGIFYKMVQQTGKAEAASLKQLA 1238          

Query:   59 EYLSEWEKE-QRRNK----PSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINE----TLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            E  S W++E Q   K    P L K + R  WK Y  LG+    E  I L QP  + KL+ +    +      L E   Y+  +    + L L+ + Y++   + GM+++I +  ++Y+K L L+  A+GQTT+GQI+NL+S+D++KF+    FLHF+W+GPL   A   +L+     + LA + VL+IL+P Q   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  ++  +R+K +         + L +A  FS S+ I+        LVG  +S+  V++ V L + +R ++   F   I    +  V+ +RI+
Sbjct:   59 ELQSYWDQEVQSATKELRTPKLTKAIIRCYWKSYSILGVFTLIEELIKLVQPVFLGKLIRYFENYDPDDMAALYEAYGYAAGVSCCTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYKKALCLSSVAMGQTTTGQIVNLLSNDVNKFDEVTIFLHFLWVGPLQAAAVIGLLWQEIGASCLAGMAVLVILMPLQTVFGRLFSKFRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAALVNDVRKKEISKIMSSSYLRGLNMASFFSASKIIVFVTFAVYVLVGNKMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSEAGVSITRIK 387          

Query: 2923 VFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGP-DQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL 3477
            VF+  A+Y    LV +K   +  F  V  Y    + +T +      +V     SI RI +++ L     +L K     L +      +E  ++  Y++   D   L+NV+  ++    + ++G  GAGKSSL+S +  L E+P+D G +             K+R  +    Q P +F GTIR+N+
Sbjct:  332 VFVTFAVY---VLVGNKMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSEAGVSITRIKKFLLLD----ELVKHSVPLLQEEKKEASVEIHDLICYWDKSLDAPTLQNVSFTVKPGMLLAVIGPVGAGKSSLLSTI--LGELPQDKGVV-------------KVRGDLTYASQQPCVFPGTIRSNI 495          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQG---------VDVHSILKQD-TTEYVIDKSRTTFNEDAI--YVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHD---------------NVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEK---MLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            Q FLS  E + + +        KP P D     +VT  N    W +   +   L+ I+  +      A++G +G GKSS+  ALLGE+   +GHI   GS++Y  QQ WI + ++  NILF  P   Q +   + A AL  D+E++P   LT +GE+G+ LSGGQ+ R+SLARA Y  AD+ L+DDPL+AVDA V   IF   I      + K  +LVTH +  L  VD ILVL EG +   G++ +++ Q            +  I+++D  TE +ID+  + F +DA+  +   +  + A N   R   ++ ++ + + +   +T S     C+     E  Q   +                VK  +YW+Y          + +  LYA+     +  +IWLS WT   D R++  A+    +K  +   +  +L    G L+   CL        KA H     MLH++L +P  FF    +GR+LNRFSKD+   D L+P  +  ++ +    +  L + S      +I+I+ L++ +W ++R Y+  S  +KRLE+V+RSP+++H S T+ G + IRA+   + F      K D   K+++  I S+RW   R++ +    ++ A  +  A++  + ++    GL ++Y + +     W VR +S++E+ + ++ER+ EY   P E P   ++      DWPS G +EF + S+ Y      VL+N++L ++  EKIGIVGRTGAGKSS+   LFRL+E     G+I +D   I  +GL  LR+ + +IPQ+PVLF GT+R NLDPF +++D D+   L  S
Sbjct:  610 QAFLSHDELDPDNVDK------KPAPSD----HAVTVVNGKFSWAKK--DPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLLKQNGAFAEFLRNYSLEDIIEEDEVTEVLIDEEES-FPDDALSNHTDMVDNEPAVNEARRQFMRQISI-MSNDLENPKTKSIRKRRCSERRPGEPPQEKKEPKVEKLIQAETAETGRVKFKVYWEY-AKAVGPILSLFICFLYASQSAAAIGANIWLSQWTN--DSRDSVTAQ----EKVHMRVGVYASLGITQGVLILANCLLCRAYSMLKAAHATHLTMLHAVLRAPQAFFEATPSGRLLNRFSKDVDTIDSLIPDNIDIWMRTFWYTVNVLLVCSALTPMFLIVIVPLMMFYWWVQRFYVATSRQLKRLESVSRSPIYSHFSETITGTSVIRAYGRNSAFVLMSDMKVDENQKSYYPGIVSNRWLGIRIEFIGNCIVLFA--AVFAVLEKENLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETPPEAPWEVED-KKPPTDWPSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAA--GGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFEKYSDDDMWNALTLS 1411          

Query: 3555 PDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPA 3908
            P KL    SEGG NLSVGQRQLIC+ARALL++ +++++DEATA +DL TD LIQ T+++ F  CTV TIAHRL+TIM+  RI+V++ G + +FD P  L + +    F  + +  G A
Sbjct: 1421 PAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIAQK--GIFYSMAKDAGLA 1536          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLA 805
            Y F+T   GMRL+  I   +Y K L +  +A   +T G+++NLMS D  +F     FL+ +W  PL  +     L+     + LA + V+++LIP    +      ++   +   D RIK+++E++NG++V+K+Y WE  F + + ++R+K L    +RK A
Sbjct:  380 YCFVT---GMRLRTAIIGAIYRKSLVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIILALFFLWQTLGPSVLAGVAVMVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVLQIRQKEL--NVLRKTA 536          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQG---------VDVHSILKQD-TTEYVIDKSRTTFNEDAI--YVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHD---------------NVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLL--SVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYW---SXXXXXXXXXXXWAL-----RRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            Q FLS  E + + +        KP P D     +VT  N    W +   +   L+ I+  +      A++G +G GKSS+  ALLGE+   +GHI   GS++Y  QQ WI + ++  NILF  P   Q +   + A AL  D+E++P   LT +GE+G+ LSGGQ+ R+SLARA Y  AD+ L+DDPL+AVDA V   IF   I      + K  +LVTH +  L  VD ILVL EG +   G++ +++ Q            +  I+++D  TE +ID+  + F +DA+  +   +  + A N   R   ++ ++ + + +   +T S     C+     E  Q   +                VK  +YW+Y          + +  LYA+     +  +IWLS WT   D R++  A+    +K  +   +  +L    G L+  S   L +  I + + LH+ +L +   +P  FF+    GRI+NRFSKDI + D+ LP        ST L+  G   AS        S   I  ++I+  AL     +R Y+  S  +KRLE+V+RSP+++H S T+ G + IRA+   + F      K D   K+++  I S+RW   R++ +    ++ A  +  A++  + ++    GL ++Y + +     W VR +S++E+ + ++ER+ EY   P E P   ++      DWPS G +EF + S+ Y      VL+N++L ++  EKIGIVGRTGAGKSS+   LFRL+E     G+I +D   I  +GL  LR+ + +IPQ+PVLF GT+R NLDPF +++D D+   L  S
Sbjct:  568 QAFLSHDELDPDNVDK------KPAPSD----HAVTVVNGKFSWAKK--DPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLLKQNGAFAEFLRNYSLEDIIEEDEVTEVLIDEEES-FPDDALSNHTDMVDNEPAVNEARRQFMRQISI-MSNDLENPKTKSIRKRRCSERRPGEPPQEKKEPKVEKLIQAETAETGRVKFKVYWEY-AKAVGPILSLFICFLYASQSAAAIGANIWLSQWTN--DSRDSVTAQ----EKVHMRVGVYASLGITQGILVMFSSFTLAMGKIQAARKLHQGLLDNKFHTPQAFFDTTPLGRIINRFSKDIYVIDEALP--------STILMFLGTFFASVATMIVIVSSTPIFAVVIVPLALVYFFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGTSVIRAYGRNSAFVLMSDMKVDENQKSYYPGIVSNRWLGIRIEFIGNCIVLFA--AVFAVLEKENLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETPPEAPWEVED-KKPPTDWPSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAA--GGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFEKYSDDDMWNALTLS 1368          

Query: 3555 PDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPA 3908
            P KL    SEGG NLSVGQRQLIC+ARALL++ +++++DEATA +DL TD LIQ T+++ F  CTV TIAHRL+TIM+  RI+V++ G + +FD P  L + +    F  + +  G A
Sbjct: 1378 PAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIAQK--GIFYSMAKDAGLA 1493          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLA 805
            Y F+T   GMRL+  I   +Y K L +  +A   +T G+++NLMS D  +F     FL+ +W  PL  +     L+     + LA + V+++LIP    +      ++   +   D RIK+++E++NG++V+K+Y WE  F + + ++R+K L    +RK A
Sbjct:  338 YCFVT---GMRLRTAIIGAIYRKSLVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIILALFFLWQTLGPSVLAGVAVMVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVLQIRQKEL--NVLRKTA 494          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQG---------VDVHSILKQD-TTEYVIDKSRTTFNEDAI--YVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHD---------------NVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLL--SVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYW---SXXXXXXXXXXXWAL-----RRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            Q FLS  E + + +        KP P D     +VT  N    W +   +   L+ I+  +      A++G +G GKSS+  ALLGE+   +GHI   GS++Y  QQ WI + ++  NILF  P   Q +   + A AL  D+E++P   LT +GE+G+ LSGGQ+ R+SLARA Y  AD+ L+DDPL+AVDA V   IF   I      + K  +LVTH +  L  VD ILVL EG +   G++ +++ Q            +  I+++D  TE +ID+  + F +DA+  +   +  + A N   R   ++ ++ + + +   +T S     C+     E  Q   +                VK  +YW+Y          + +  LYA+     +  +IWLS WT   D R++  A+    +K  +   +  +L    G L+  S   L +  I + + LH+ +L +   +P  FF+    GRI+NRFSKDI + D+ LP        ST L+  G   AS        S   I  ++I+  AL     +R Y+  S  +KRLE+V+RSP+++H S T+ G + IRA+   + F      K D   K+++  I S+RW   R++ +    ++ A  +  A++  + ++    GL ++Y + +     W VR +S++E+ + ++ER+ EY   P E P   ++      DWPS G +EF + S+ Y      VL+N++L ++  EKIGIVGRTGAGKSS+   LFRL+E     G+I +D   I  +GL  LR+ + +IPQ+PVLF GT+R NLDPF +++D D+   L  S
Sbjct:  610 QAFLSHDELDPDNVDK------KPAPSD----HAVTVVNGKFSWAKK--DPPALQHINVMVPQGSLLAVVGHVGCGKSSLVAALLGEMEKLEGHISIRGSVAYVPQQAWIQNATLRDNILFGRPYVEQKYRCVLEACALTPDLEVLPGGDLTEIGEKGINLSGGQRQRVSLARALYSEADVYLMDDPLSAVDAHVAKHIFDHVIGPEGALRGKTRILVTHGISFLPQVDNILVLVEGMVSEMGSYQDLLKQNGAFAEFLRNYSLEDIIEEDEVTEVLIDEEES-FPDDALSNHTDMVDNEPAVNEARRQFMRQISI-MSNDLENPKTKSIRKRRCSERRPGEPPQEKKEPKVEKLIQAETAETGRVKFKVYWEY-AKAVGPILSLFICFLYASQSAAAIGANIWLSQWTN--DSRDSVTAQ----EKVHMRVGVYASLGITQGILVMFSSFTLAMGKIQAARKLHQGLLDNKFHTPQAFFDTTPLGRIINRFSKDIYVIDEALP--------STILMFLGTFFASVATMIVIVSSTPIFAVVIVPLALVYFFVQRFYVATSRQLKRLESVSRSPIYSHFSETITGTSVIRAYGRNSAFVLMSDMKVDENQKSYYPGIVSNRWLGIRIEFIGNCIVLFA--AVFAVLEKENLSPGLVGLSVSYALQVTMSLNWMVRMTSDLESNIVAVERVKEYSETPPEAPWEVED-KKPPTDWPSEGNVEFADYSVRYREGLDLVLRNISLRVKGGEKIGIVGRTGAGKSSMTLCLFRLLEAA--GGEITIDGVKIKEIGLHDLRSKLTIIPQEPVLFSGTLRMNLDPFEKYSDDDMWNALTLS 1410          

Query: 3555 PDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPA 3908
            P KL    SEGG NLSVGQRQLIC+ARALL++ +++++DEATA +DL TD LIQ T+++ F  CTV TIAHRL+TIM+  RI+V++ G + +FD P  L + +    F  + +  G A
Sbjct: 1420 PAKLALECSEGGENLSVGQRQLICLARALLRKTRILILDEATAAIDLETDDLIQSTIRTQFEDCTVFTIAHRLNTIMDYTRILVLDKGQIAEFDTPVNLIAQK--GIFYSMAKDAGLA 1535          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLA 805
            Y F+T   GMRL+  I   +Y K L +  +A   +T G+++NLMS D  +F     FL+ +W  PL  +     L+     + LA + V+++LIP    +      ++   +   D RIK+++E++NG++V+K+Y WE  F + + ++R+K L    +RK A
Sbjct:  380 YCFVT---GMRLRTAIIGAIYRKSLVITNEAKRSSTVGEVVNLMSVDAQRFMDLTTFLNMLWSAPLQIILALFFLWQTLGPSVLAGVAVMVLLIPFNAVIAMKTRAYQVEQMQYKDARIKLMNEILNGIKVLKLYAWEVSFKEKVLQIRQKEL--NVLRKTA 536          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTC--AXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCI--SELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK---------------QDTTEYVI--------DKSRTTFNEDAIYVSEITEDRAT---NLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSR-----WFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDS--QLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            + FLSL E + + +  S S +        + C S+        W+E      IL DIS  L  P+ C  A++G +GSGKSS+  ALLGEL    G +   G ++Y +QQ WI   S+  N+LF  P +   + + + A AL++D+  +P    T +GE+G+ LSGGQ+ R+SLARA Y  A + LLDDPL+AVDA VG  IF + I  S L   +  +LVTH L  L  VD+I+VL  G +   G+++E++  G     +L+               QD   +VI        D+  +T +  A     +TE R      L ++ +S   T   +S    G   +   S        + E     ++KL++   Y      A    L  +L+    T  + T++WLS W  E           Y+      +G +   LS     L+ V+ +F  C+ +  +LH  +L + L SPI F++    GRI+NRFSKD+ + D++LP T   F+ + C  +F + +        ++  + L++I++ ++R Y+  S  +KRLE+  RSP+F+H   ++ G  T+RAF+ +  F     +  D   +  +  I S R     W  F     C V       +  A++    +     GL ++Y + +  +  W VR SSEVE+ + ++ER+ EY   P   P+   E++S     DWPS G +EF++ S  Y      VL+N++  I+  EK+GIVGRTGAGKSSL   L R+VE     G I +D  DIS +GL  LR+ I +IPQDPVLF G++R NLDPF   +D++V   L+
Sbjct:  594 RNFLSLEELDPHAVDRSPSHLR-------ESCVSIEGGTFTWSWDE----PPILHDIS--LAVPRGCLLAVVGTVGSGKSSLMAALLGELNKLGGSVAVKGQVAYVAQQAWI-QNSLRDNVLFGRPLDETWYREVLQACALEQDLLALPAGDNTEIGEKGINLSGGQRQRVSLARAIYSKASVFLLDDPLSAVDAHVGKHIFERVIGPSGLLAGQTRVLVTHGLSFLPHVDRIVVLTAGRVSESGSYSELMLSGEAFSELLRIHGQGDGAGEDSPASQDDGPHVIIDLRSPGPDEVLSTCSNIADMEPVMTEPRRMLMRQLGSQEASGSGTTQGVSTETRGHKETQPGSTLM-----QPESMETGHMKLSVVLHYLR-AVGAPLSTLALLLFCANYTTMLGTNVWLSEWAGEPVVNGTQRNTGYRLGVYSALGAVQSVLS-----LVMVLMVFKGCLRAAGSLHLALLDNKLHSPISFYDVTPLGRIINRFSKDVFMIDEVLPPTFLMFLGALCNSIFTILIIVISTPVFVVAAIPLVVIYFFVQRFYVATSRQLKRLESTVRSPVFSHFGESVAGAATLRAFRQEERFVIAGDRAVDALQRTSYPSIVSQRRVGAVWLEFL--GACVVLFA----AMFAVLSRDSLKAGTVGLSVSYAMQVTVVMSWMVRMSSEVESNIVAVERVKEYSETP---PEADWEVESCRPPADWPSQGHVEFRDYSTRYREGLDLVLRNISCDIKGGEKVGIVGRTGAGKSSLTLCLLRMVEAA--SGAIAIDGVDISRIGLHDLRSRITIIPQDPVLFGGSLRDNLDPFGHHSDAEVWEALE 1388          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            L +T   LP  +    +EGG N SVGQRQL C+ARALL+R +V+V+DEATA VD+ TD+LIQ T+++ F  CTVLTIAHRL T+++  R++V+++G + +FD P +L S R DS F ++ +  G
Sbjct: 1392 LGETARALPGGIQHECAEGGENFSVGQRQLACLARALLRRTRVLVLDEATAAVDVETDALIQGTIRTHFHACTVLTIAHRLHTVLDCTRVMVLSSGQIVEFDSPDVLLS-RKDSAFHKMARDAG 1514          

Query:   98 KPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGL 889
            +PSLI+ +       Y    +    ++ ++ + P ++  L+ F    +         + L+ +  I   ++ + ++      G+RL+  +  ++Y K L + Q A      G++  LMS D+         L+F+W  PL        L+     + LA + V+L+LIP    +       +  I+   DER++ +SE ++G++++KMY WE  F  VI ++R   L       L ++ + ++           ++C  FLV L
Sbjct:  287 EPSLIRAMALAFGPRYLVGSVYKLLQDILSFASPLLLSHLIRFVGDNSRPTWHGYALAGLMFLCAIATSMLAHQHFHAGFVTGIRLRSALTGLLYRKALMITQAARLSCAGGELTTLMSVDVQHMADITNNLNFVWSAPLHICLAMYFLWQHLGPSVLAGVAVMLLLIPFNAFIALNIRTLQAQIIKKRDERVRTLSEALSGVRIIKMYAWEGRFRDVILRVREHELAV-----LGRAAYFSM------LSAFTWLCSPFLVAL 539          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTL---QSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQF-DHPHLLFSDRPDSTFIQLVQQTGPAEE 3914
            LP    + + E G NLS GQRQ + +ARA+  +A V ++D+  + VD H    I + +       A  T + + H LS + + DRI+V+  G V +   +  L+ S    S  +++  Q   A E
Sbjct:  727 LPAGDNTEIGEKGINLSGGQRQRVSLARAIYSKASVFLLDDPLSAVDAHVGKHIFERVIGPSGLLAGQTRVLVTHGLSFLPHVDRIVVLTAGRVSESGSYSELMLSGEAFSELLRIHGQGDGAGE 851          

Query: 1435 RTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKD--KXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNL-YWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLF------LICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDS 3504
            R GS++Y +Q+PWI + ++ +NI F  P N + ++  I   +L  DI+I+P    T++GE+G+ LS GQ+ RIS+ARA Y   +++ LDDP  A+D  +   +    I  L  +  + V+LVTH+L  L   D I+ + +G +   GT  +I +   +++ + K+     +++K      ++ I  S    +R  NL     SKE        V+   +  +  +  N    +  +  SH    L L  W+ +        ++L+ +            D WL+ WT+      A +     +     +  +L ++      L  V+CL        + + + + LH+++L  I+ +P++FF+    G ILNRFS D+ + D L+P + +  + S+   L  + + +Y     ++ ++ L ++ + +++ +   S  ++ L+  T+ PL  HI  T+ G+ TIRAF+ ++ FR+   +  D  +  F    +++RW   R+D +    ++    + +   ++  +++   GL L Y + +     W VR  +++E Q+ +I+R+   + +  E  + + EL +   DWP  G I+   +S  Y+   +  LKN++ +I+  +K+GI GRTG+GKSSL   LFR+++I    G I +D  DIS + L  LR+ +++I QDPVLF G+IR NLDP    TDS
Sbjct:  765 RRGSVAYAAQKPWILNSNVQENITFGSPFNEERYKAVINTCSLQPDIDILPQGDRTQIGEKGINLSAGQRQRISVARALYQHTNVVFLDDPFTALDIHLSDHLMHSGILGLLHNDTRTVVLVTHKLQYLTHADWIIAMKDGTVQREGTLKDIQTSDPELYEMWKE-----LMNKQDEELQKETIIESRTALER-KNLRRAMYSKE--------VLVKTSFEDEENGIN---SEHFDSMSHLLPGLPLGEWRSYLAASGWPLLLLIVLSQLCKHVSMAAPDFWLAMWTSRALNVTAQNHNCTSSSVCLCLQSLLASIFAVLCCLAVVMCLISSLAVEWVGLKAARGLHKRLLGRIVRAPLRFFDTTPLGSILNRFSADLHMIDQLIPSSTESLVRSSLFSLSAVSVIAYVTPIFLVALVPLALVHYFIQKHFRIASKDLQELDENTKLPLLLHIMETVDGIATIRAFRHESQFRQRIFELIDANNVPFLFLSAANRWLEVRMDYIGASIVLATAMASITRSFYSGLDSGLVGLGLTYALLVSIYLNWVVRNLADIEVQLQAIKRVNNLMKVEIEDDERSPELHAVPEDWPHRGEIKINRLSARYDASLKPALKNLSSVIQPGQKVGICGRTGSGKSSLSLALFRMLDIFD--GSITIDDVDISKIPLSLLRSRLSIILQDPVLFSGSIRFNLDPEARSTDS 1445          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQ 3893
            +  LP  L + V EGG N S+GQRQL C+ARA +++  ++++DEATA +D+ T+ ++QK + + FA  TV+ IAHR++ I+++D ++V+N G++++ D P  L ++ PD+ F  LV+
Sbjct: 1460 VKALPGGLDATVREGGENFSLGQRQLFCLARAFVRQTAILIMDEATAALDMATEKILQKVVMTAFADRTVVMIAHRVANILDADVVLVLNQGLLEENDSPANLLAN-PDTIFSSLVK 1575          

Query:  323 YFLTMKMGMRLKIGIGAIVYEKILKLNQKAL--GQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAK-SLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLT 919
            Y+  ++ G++ +  +  ++Y+KIL L+  ++  G+ TS  I N+++ D ++    L     +W  P+  +    +LY     + L    V+ +L P Q  +     + + L L  +  RIK  SEL++G++++K+Y WE +F   + + R K L     R L+  +++ AL    +  I I  +   F+  + LSS  + L+
Sbjct:  376 YYKAIETGIKFRAAVQTMIYDKILHLSTSSVSRGKMTSRYISNVVTVDSNQLMWFLFLCPNLWALPVQIIVGVSLLYSLLGVSALIGAAVIALLAPLQYCIATKLARAQKLTLEHSSSRIKQTSELVHGIKLLKLYAWEQVFCSTVEETRSKEL-----RSLSTFAIYTALSTFMNAAIPITAVMATFVTYVHLSSPDITLS 572          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLH-TDSLIQKTLQSTFAH--CTVLTIAHRLSTIMNSDRIIVINNGIVDQ 3830
            I+ LP    + + E G NLS GQRQ I +ARAL +   V+ +D+    +D+H +D L+   +     +   TV+ + H+L  + ++D II + +G V +
Sbjct:  811 IDILPQGDRTQIGEKGINLSAGQRQRISVARALYQHTNVVFLDDPFTALDIHLSDHLMHSGILGLLHNDTRTVVLVTHKLQYLTHADWIIAMKDGTVQR 909          

Query: 3223 DQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEI----------PRDCG-KIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL---DPFNE 3492
            +  +L ++N+ I   +   +VG+ G GKSSL+S     + +          PR        +RQ+       + R S+A   Q P +    ++ N+    PFNE
Sbjct:  692 EPSLLTDINICIPHGQLTMVVGQIGCGKSSLLSATLGEMHLVSGSVYWNSSPRQQSVNTKNNRQERRASTFCRRRGSVAYAAQKPWILNSNVQENITFGSPFNE 795          

Query: 2440 LHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAG-KSSLISLLFRLVEIPRDCG-KIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            LH+ +   +L S +  F+    GR+LNRFS+D+   D  +P   + FI +  LVLF LG+ +    W ++ ++ L ++F  + +        +KRL+ ++ SP  +H++ +LQGL TI A+   + F   +Q+  D      FL+  + RW A RLD +    I T   + + ++ H +I  +  GL ++Y + L G  Q+ +R +SE E + TS+ERI  YI AL  E P    E      +WP  G + FQ+V + Y      VLK V   I+ RE +GIVGRTG+G KSSL   LFRLVE+   CG  I +D   I  +GL  LR+ +++IPQ+PVLF+GTIRTNLDP   +TD  +   L+
Sbjct:   11 LHDSLFLKVLRSSMTVFDTTPTGRLLNRFSRDMDEVDVRMPFQAELFIQNVILVLFCLGVIAAVFPWFLLAVIPLCVLFLIINKISRVFIRELKRLDNISHSPFMSHVAASLQGLPTIHAYSKSDEFLHRYQELLDTNQACLFLFSCAVRWLAVRLDIISVALITTT--ALMMVLMHGQIPAAYAGLAISYAIQLTGTFQFTIRLASETEARFTSVERIQHYIEALEEEAPDHVPE-KPLAAEWPQHGSVSFQDVEMRYREGLPLVLKRVTANIKPRENVGIVGRTGSGCKSSLGVCLFRLVEL---CGGSISIDGVPIGDIGLGDLRSRLSIIPQEPVLFIGTIRTNLDPLGLYTDEQIWEALE 369          

Query: 3537 DTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            D I +LP KL + V E G N SVG+RQL+C+ARA+L+ +K++++DEATA +D  TD+LIQ+T++  F  CT+LTIAHRL+T+++ DRI+V++ G V +FD P  L  +R       +V   G
Sbjct:  375 DNIGQLPQKLETEVVENGENFSVGERQLLCVARAILRHSKILLLDEATAAIDTETDTLIQETIRRAFGDCTMLTIAHRLNTVLSCDRIMVMDQGQVVEFDSPSTLLENRASRFAAMMVAGEG 496          

Query: 2422 IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYH-KKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            + + K +H  +LH +L +P+ FF+    GRI+NRFS D+   DD LP  +  F+     ++  + +  Y   W  +++L L  +++ +++ Y   S  +KRL +VT SP+++H + +L GL  I+AF++ + F +E + + +   +  F  ++   W   RL ++  V IV ++ +   L +H + ++    GL + Y +G+ G     V   ++ E QM S+ER+ EY  + +E         S   DWP  G + F  V L Y       L  ++  I   EK+GIVGRTG+GKS+L S+LFR+V++    G I +D QDIS L LK+LR+++A+IPQDP LF  T+R NLDP   + D ++  VL+
Sbjct:   48 VCAAKNIHVTLLHKVLQAPVSFFDATPTGRIMNRFSSDLFTVDDSLPFIMNIFMAQLFGLVGAIVVMCYGLPWMALVLLPLAGVYYCVQKYYRFTSRELKRLGSVTLSPIYSHFAESLSGLAIIKAFRATDRFTRENEARLELNQRCQFAAVAVMHWLDVRL-QMMGVVIVVSLAALAVLEHHLRGVDPGLVGLAIAYALGINGRLSGLVSSFTQTETQMVSVERVQEYRGIASEEAHRHPTHVSP--DWPQGGALTFDKVFLTYRPGLPFALNGISFCINSWEKVGIVGRTGSGKSTLFSVLFRIVDVQH--GAIYIDNQDISKLALKQLRSNLAIIPQDPFLFSDTVRNNLDPKGSYQDHELWEVLE 411          

Query: 3564 LYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQT 3899
            L + V+E G + S GQRQL+C+ARA+L +AK++ IDEATA+VD  TD L+QKT++S F + TVLTIAHR +TI++SDR++V+  G V +F  PH L  D P S   +L+ ++
Sbjct:  425 LQAEVAERGRDFSCGQRQLLCLARAMLFKAKILCIDEATASVDQDTDVLLQKTIRSEFVNSTVLTIAHRPNTILDSDRVLVLQGGRVLEFASPHDLLQD-PRSALSRLLSKS 535          

Query: 2428 SCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTE-YPKLTKELDSQLID-WPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDP 3483
            + + +H  ML  I+ +P+++F+    G ILNRFS D +I D  +P TL+  + S  L L  LG+ +Y     +I ++ L I ++ +++ +   S  ++ L+  T+ PLF+H S T++G+TTIRAF+ +  FR+   +  D  + ++    +++RW   RLD +    ++ A  + +   ++  ++++  GL L Y + +     W VR  +++E QM +I+R+   + + TE Y  L  +  +Q+ D WP +G I+ + +S+ Y+   + VLK+VN  I+  +K+GI GRTG+GKSSL    FR+V+     G+II+D  DI+ + L  LR+ +++I QDP+LF G+IR NLDP
Sbjct:   31 TARNVHNNMLKRIVLAPMRYFDTTPLGHILNRFSADTNIMDQQIPTTLESLMRSALLCLSALGIIAYVTPIFLIALVPLAIAYYFIQKYFRVASRDLQELDDSTQLPLFSHFSETVEGITTIRAFRHEVRFRQRLLELTDANNISYLFLSAANRWLEVRLDYIGACIVLIASVASITDSWNNTLSSARVGLCLTYALMVSNYLNWVVRNLADIEVQMGAIKRVNNLLQIETESYDGLLSQ--AQVPDNWPQSGEIKIEELSVRYDSTLKPVLKHVNAHIQPSQKVGICGRTGSGKSSLSLAFFRMVDTFE--GRIIIDNIDIAKIPLHTLRSRLSIILQDPILFSGSIRFNLDP 380          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQ 3893
            L   +  LP  L + V+E G N SVGQRQL C+ARA +++  + ++DEATA++D+ T+S++QK + + FA+ TV+ IAHR+ TI+ +D ++V+  G V ++D P  L +   DS F   V+
Sbjct:  398 LKHVVKALPGGLDAMVTENGENFSVGQRQLFCLARAFVRKTSIFIMDEATASIDMATESILQKVVMTAFANRTVVIIAHRVHTILTADLVMVLKRGSVLEYDTPSTLLAH--DSMFASFVR 516          

Query: 1276 WNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQF-EQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNE----------DAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLIC-IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTS 3531
            W      +  LK+I+F  K      I+G++GSGK+++   +LG+L   KG     GS++Y SQ PWI +G++ +NILF    + +F E+TI A AL  D+ I+ +   T VGE+G+ LSGGQKAR+SLARA Y  AD  LLDDPLAAVD  V   +    +    L   K  +L T+++  L   D I +L  G +   GT++EI     D  S L +    Y   K+    NE          ++    E   ++   LN+ +      + L         + +     N++ R+  EQ     VK N+Y +Y    C+   V +  +    +M L V  ++WL  W+ E++ R  S+     N   +L     L + +    L+  I L++ C I++ K LH  M +S+L +P+ FF     GRILNRFS DI   D LL  T   F ++   V F + +     +  I II+ L + +   ++ Y+  S  ++RL+++TRSP+++H   TL GL T+R +  Q  F    Q + D    AF+  I+++RW A+RL+ + ++ I+ A    V  +    +     GL L+Y + +     W VR + EVE  + S+ERI EY  L +E P L  E      +WPS G I+F N S  Y      VLK++N+ I+  EK+GIVGRTGAGKSSL   LFR++E     G I++D   I+ +GL  LR  +++IPQD  +F GT+R N+DP N++TD  +   L+ S
Sbjct:  636 WQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITK---DADSPLWKLLNNYG-KKNNGKSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGSIDFGDDENIAKREHREQ---GKVKWNIYLEY-AKACNPKSVCVFILFIVISMFLSVMGNVWLKHWS-EVNSRYGSNP----NAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEAP-LIVEGHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASE--GNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELS 1385          

Query: 3558 DKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEE 3914
            D L + ++EGG NLSVGQRQL+C+ARA+L  +K++V+DEATA VD+ TD ++Q+T+++ F   T+LTIAHRL+TIM+SDRIIV++NG V +FD P  L SD   S F  L  + G   E
Sbjct: 1397 DGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDN-KSLFYSLCMEAGLVNE 1514          

Query:   71 EWEKE-QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN-ETLTEXXXXXXXXXXXXXXXXXXR-------------------NPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYM--CCAFLV-----GLPLSSQLVWLTVILIN 934
             WE E ++++ PSL   +CR    +           + +  +QP ++  L+ F    N E   +              L ++R                   + Y+      GM +K  + A++Y+K L L+ +A G +++G I+NLMS D+ K +   Q+L+ IW GP   +     LY     +    +++L+I++P    L ++  K +   +   DER +++SE++N ++ +K+Y WE  + + + ++R    L    +     L   +  +  +F I+ ++  CC F V        L++ LV+  + L N
Sbjct:  262 NWENELKQKSNPSLSWAICRTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTK-----LGCYMAVTSFQFNIVPFLVSCCTFAVFVYTEDRALTTDLVFPALTLFN 572          

Query: 1252 TFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIM----------------RTGSLSYTSQQPWIFSGSILQNILFNLPKNN-QFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCIS-ELFKDKX-XXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVK------LNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTE------------------------MDKRNASDAEFYKNDKPFLIG------LILLTLSTFAGGLLSV---ICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
             FEN    W+++   ++ LKD++   K  +   +IG  GSGK+S+ MALLGE+ L  G ++                 T S++Y SQ  W+ + ++  NILFN P N  +++  + A  L RD EI+    LT +GE+G+ LSGGQK R+SLARA Y  A  +LLDD L+AVD+     I+  CI+  L +D+  +L+  +    L++ + +++L +G +   G   +++ +G+     L + +   ++ ++ ++ N        +    +T+L+N  + KEQ V + +     E      S    + R E  +   +  K      L++Y  Y  +      V  +  L+     LY+    W+  W +                         +D R +S       +     G      L+L  +  FA  LL     I  F+  I + + +   +L+ +L S I+FF+    GRI+NRFSKDI   D  L   +Q    S    L  + L ++     + + + + I+++ +   YM  S  +KR E+++RSP++ H S TL G+TTIRAF  +  F +E   K D  +K FF    ++RW AFR+D + ++ I  A      L     +++   G+ L Y +       W VR  SEVE  M S+ER+ EY+ +  E     KE+      WP  G+IE  ++SL Y      V+KNV+  ++ + KIGIVGRTGAGKS++I+ LFR +E   + G I +D  DIS + L++LR SI +IPQDP LF GTI+TNLDP++EF+D  +   L+
Sbjct:  695 AFENSTISWDKD-NQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNEARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGDPIDMLQKGLFGEDELVKSS---ILSRANSSAN--------LAAKSSTSLSNLPAVKEQQVSVNNNSSHFEAKKLQKSLRTEAERTEDGKLIKEETKEEGVVGLDVYKWYLKIFGGWKIVSFLASLFLIAQLLYIGQSWWVRAWASHNVIAKIIPRAQRAIAFISKKASHLIDWRGSSQISMASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVLHSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQFLSVAIVVSILYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENNKPFFYLWVANRWLAFRIDMIGSLVIFGA--GLFILFNINNLDSGMAGISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPP--QWPQDGKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLE--PETGHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALK 1492          

Query: 3537 DTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            + +NK  D L S +SEGGSNLS GQRQL+C+AR+LL+  K+I++DEATA++D  +D+ IQ+T++  F   T+LTIAHRL ++++ D+I+V++ G V ++DHP+ L  ++  S F  + + +G
Sbjct: 1520 ENVNKFLD-LSSEISEGGSNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVIDYDKILVMDAGEVKEYDHPYSLLLNK-QSAFYSMCEHSG 1639          

Query: 3570 SPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHC---------TVLTIAHRLS-TIMNSDRIIVINNGIV-DQFD 3836
            + + E G  LS GQ+Q + +ARAL   A+ +++D+  + VD HT S I       + +C         T + ++H ++ T+ N++ ++++ +G V DQ D
Sbjct:  826 TEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWI-------YDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGD 918          

Query: 3136 TKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCV-LKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIV----DRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNL---DPFNE 3492
            TK+ D   ID P+  R  F+N ++ ++  +Q   LK++N+  +  +   ++G TG+GK+SL+  L  L E+    GK++V     RQ++  +       SIA   Q   L   T++ N+    PFNE
Sbjct:  679 TKKYDQLTID-PNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMAL--LGEMYLLNGKVVVPALEPRQEL-IVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNE 801          

Query:  383 EKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIA-YMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            +K +  ++++      G IINLM+ D  K      +LH      ++TV    +LY     A +  +++++ ++P    L K     +   L++TD RI+ ++E    ++++K + WE  F K I  +R   L    +R +  S+   L F     +  A +    ++ G  L++ + +  + L   +R  + DR S  ++  +  +V+  R+Q
Sbjct:  460 QKSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVVALALLYRLLGFAAIVGVLIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQAIRIIKYFSWEENFEKDINTIRENELSLLLMRSIVWSISSFLWFVTPTIVTAASFAYYIYVQGEVLTTPVAFTALSLFTLLRDPL-DRLSDMLSFVVQSKVSLDRVQ 671          

Query: 1306 LKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILK---QDTTEYVIDKSRTTFNE--DAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYF--TVGCSAFFVVLMF-ILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKP-FLIGL---ILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNY-WSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIA-LPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVL 3522
             KD++F +K  +   I G IG+GKSS+  A+ G +  + G +   G L      PWI + S+  NI+F  P N + +++ +   +L  D++I+P   +T +GERG+ LSGGQKARI+LAR+ Y   DI L DD L+AVD+ VG  I  +C++ +  +K  +L THQL L++   +++VL     +  GT +E+ ++   + ++L+   Q++ +   ++      E     Y SE+ E   T L  + +   QT      V  G T+S    A N             ++ L +Y +Y    VG   F  + ++ IL   T    +F+ +WLS+WT             +KN  P F +GL    +     F  G  +++C   + I + K L+ + +  IL +P+ + +    GRILNRF+KD    D+ L  +L+  + S    + G+ +       W  I I FLL+IF  +   Y +    IKRLEAV RS ++ +++  L G+ TI+A++SQ  F  +     ++ ++A +L +   RW    LD V   F +     CV   +   I+ +  G++L YV+ L GL    +R  ++ EN M S ER+  Y   LP E      E+ +    WPS G I F+NV   Y      VLKN+NL I+  EKIGI GRTGAGKS+++S L+RL E+    GKI++D  DIS LGL  LR  +A+IPQDPVLF GTIR NLDPFNE TD ++   L
Sbjct:  604 FKDLNFDIKKGEFIMITGPIGTGKSSLLNAMAGSMRKTDGKVEVNGDL-LMCGYPWIQNASVRDNIIFGSPFNKEKYDEVVRVCSLKADLDILPAGDMTEIGERGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDSRVGKHIMDECLTGMLANKTRILATHQLSLIERASRVIVLGTDGQVDIGTVDELKARNQTLINLLQFSSQNSEKEDEEQEAVVAGELGQLKYESEVKE--LTELKKKATEMSQTANSGKIVADGHTSSKEERAVN-------------SISLKIYREYIKAAVGKWGFIALPLYAILVVGTTFCSLFSSVWLSYWTENK----------FKNRPPSFYMGLYSFFVFAAFIFMNGQFTILCA--MGIMASKWLNLRAVKRILHTPMSYIDTTPLGRILNRFTKDTDSLDNELTESLR-LMTSQFANIVGVCVMCIVYLPWFAIAIPFLLVIFVLIADHYQSSGREIKRLEAVQRSFVYNNLNEVLGGMDTIKAYRSQERFLAKSDFLINKMNEAGYLVVVLQRWVGIFLDMVAIAFALIITLLCVTRAF--PISAASVGVLLTYVLQLPGLLNTILRAMTQTENDMNSAERLVTYATELPLEASYRKPEM-TPPESWPSMGEIIFENVDFAYRPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSALYRLNELT--AGKILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKNLDPFNERTDDELWDAL 1323          

Query: 3576 VSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAE 3911
            V E GSN S+G+RQL+ + RAL++++K++++DEAT++VD  TD  IQ  +   F  CT+L IAHRL TI+N DRI+V+  G V +FD P  LFS + DS F  +  ++G  E
Sbjct: 1360 VEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEFGDCTILCIAHRLKTIVNYDRILVLEKGEVAEFDTPWTLFS-QEDSIFRSMCSRSGIVE 1470          

Query: 1393 ALLGELPLSKGH--------IMRTGSLSYTSQQPWIFSGSILQNILFNLP-KNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCI---SELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAI---YVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSR--------------DELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLI-LLTLSTFAGGLLSVICLFLIC-IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKS-QNWFRKEFQKKQDRYSKAF-FLYISSSRWFAFRLDEV-CTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDV 3510
            A+LG+LP   G         I+R+ S++Y SQ+ WI + S+ +NILF      + ++ TI A  L  D++I+P+   T VGE+G+ LSGGQKAR+SLARA Y  ADI LLDD L+AVDA V   I    +   + L K+K ++L T+ + +LK    I  L  G ++  G + +++++  +  S LK+   E+  D      NE  +   + SE   D    L    S  E  V   S +   +  S  +S   L  R               + E+     VK  +Y  Y    C    VVL F+    T    +  + WL +W+ E +++N S+   +       +G+  L+ +++ A   L  I + L C I   K LHE M  S++ SP+ FF     GRI+NRFS D+   D  L      F  S    L  + L  Y   W ++  +FL++I+   +  Y+ +S  +KRL +++ SP+ + +S +L G + I A+   + +    ++K Q  Y+  F F + S++RW + RL  +  T+ + TAI +   +   +++++   GL+++Y + + G   W VR +  +E  + S+ERI EY  LP E   +  E      +WPS G IEF+N S  Y      VL N+N+ IE  EK+GIVGRTGAGKS+L   LFR++E P +  KII+D  DIS +GL  LR+ +A+IPQD   F GT++TNLDPFN +++ ++
Sbjct:  684 AILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNT-SKLKKLLEEF--DSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEVVTESELELIKANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYIK-ACGVLGVVLFFLFMILTRVFDLAENFWLKYWS-ESNEKNGSNERVW-----MFVGVYSLIGVASAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQ--YNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQSINPEKRPDE-NWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILE-PTEG-KIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDEL 1408          

Query: 3558 DKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTG 3902
            D L   ++E GSNLSVGQRQL+C+ARALL R+K++V+DEATA+VD+ TD +IQ T++  F   T+LTIAHR+ T+++SD+IIV++ G V +FD P  L SD+  S F  L ++ G
Sbjct: 1443 DILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDK-TSIFYSLCEKGG 1556          

Query:  314 NPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLV-----GL-------PLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            N +Y    + G+ ++  + ++VY+K L+L      + ++G I+NLMS D+ + +   +    I   P+  +     LY    +A +  ++ + I++P    L +   K     +   D RIK ++EL+N ++ +K+Y WE   +  +  +R    L  F RK+            S  I  A+ C   +V     GL       PLS  +V+ ++ L N + ++I    S+ I   I+  V+  R++
Sbjct:  352 NQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNF-RKIGIV---------SNLIYFAWNCVPLMVTCSTFGLFSLFSDSPLSPAIVFPSLSLFNILNSAIYSVPSM-INTIIETSVSMERLK 587          

Query: 1438 TGSLSYTSQQPWIFSGSILQNILF-NLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCIS-ELFKDKX-XXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDEL---EQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKR---------------------NASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIAD-DLLP-VTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLID---WPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVL 3522
            T S +Y SQ  W+ + ++  NI+F N    +++ + I A  L RD+EI+P   LT +GE+G+ LSGGQK RISLARA Y  A  +LLDD L+AVD+     I+  CI+  L K++  +L+  +    L++    +VL  G +   GT  E+ S+G     + K+   +YV   SR + NE              N N   + ++     + PV       N++   N  +  +L   E+ S+  +  ++Y  Y         +  +F LY T   L++    W+  W  + + R                     N  +A FY     FLIG+I   L  F       +  FL  + + + +   +L  +L + I+FF+    GRI+NRFSKDI   D +L+P + +  F L  C  +  L       + ++ +I+F+L   + + + Y+  S  +KRL+++T+SP+F H S TL G+ TIRAF  +  F  E   K D+ ++AFF    + +WF+FR+D +   FIV A  S + L+    I++   G+ L Y +       W VR  S  E  M S+ER+ EY ++  E      E    L++   WP  G IE +N+SL Y      V++NV+  ++ + KIGIVGRTGAGKS++I+ LFRL+E    C KI  D QDIS + L  LR SI +IPQDP+LF GTI++N+DP++E+ +  +   L
Sbjct:  745 TNSFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDLTEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPLMKNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITELQSKG-----LFKE---KYVQLSSRDSINEK-------------NANRLKAPRKNDSQKIEPV-----TENINFDANFVNDGQLIEEEEKSNGAISPDVYKWYLKFFGGFKALTALFALYITAQILFISQSWWIRHWVNDTNVRINAPGFAMDTLPLKGMTDSSKNKHNA-FYYLTVYFLIGIIQAMLGGF-----KTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAVIVFVLY--FFVGKWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNNRAFFYLSVTVKWFSFRVDMI-GAFIVLASGSFI-LLNIANIDSGLAGISLTYAILFTDGALWLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKDGEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKI--DGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYDEKKIFKAL 1433          

Query: 3564 LYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDR--------PDSTFIQLVQQTGPAEEKKLR 3926
            L++ ++EGG NLS G+RQL+ +AR+LL+  K+I++DEAT+++D  +D LIQ  ++S F   T+LTIAHRL ++++ DRIIV++ G V ++D P  L  D          DS  ++L++Q      K ++
Sbjct: 1464 LHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSIDYDSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIFYSMCRDSGGLELLKQIAKQSSKMMK 1592          

Query:  326 FLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTS---------GQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFII-IAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRI 1015
            F++ K+ +R++  +   +Y K L+       +T+S         G IINL+S D  K      +L+      ++ +    +L+ F   +  A I ++L++ P    L  L  KF+   L  TD+RI  ++E +  +++VK + WE   I  I  +R+K L     + L  S+   L F     +  + +  C F+    L++ L + T+ L   ++  + D+ S  ++     +V+  RI
Sbjct:  402 FVSDKICLRIRAILIGEIYAKGLRRRLFTSPKTSSDSDSISANLGTIINLISIDSFKVSELANYLYVTVQAVIMIIVVVGLLFNFLGVSAFAGISIILVMFPLNFLLANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLKKSLVWSVTSFLWFVTPTLVTGVTFAICTFVQHEDLNAPLAFTTLSLFTLLKTPL-DQLSNMLSFINQSKVSLKRI 640          

Query: 1156 LSLSEFE----MNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKN-NQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDT-----TEYVIDKSRTTFNEDA---IYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKY---FTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKND------KPFLIGLILLTLSTFAGGLLSVICLFLIC--------IYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDF--ILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVL 3522
            +SL  FE    ++E+ S    +   L    ++C  V  +   A WN+ +     L  +SF + +     +IG +GSGKSS+  A+LGELPLS+G I   G ++Y SQQ W+++ ++  NILF    + +++   I A ALD+D E++     T VGERGV LSGGQ+ARISLARA Y   DI LLDDPL+AVDA VG  +F +CI    KDK  +LVTHQL  LK  D+I+VL +G  I  GT+ ++        S+L ++       E   D   T F       + V E+   RA N                  +     S +S+A  L+   E E      V    Y  Y   F    +  F++ +F +      + +F D+WL+ W    +  + + A +  +       +P L       LS +A  +  +  L LIC        I + + LH  M HS++ + + FF+ NS GRILNRFSKDI + DD +P  L D   I  +CL +  L  AS  N  SI I+L ++ +F+  R  +M  S  +KR+E + RSPLF H STTL G+ TIRA+  +  F  +F    D +S+A++ Y++   W   RL  +  VF++  +    AL     ++    GL+L+Y + L  L +  V +S+EVEN MTS+ER+ EY +LP E  K+T  +     DWP  G+I F N+S  Y      VL NV  +I+  EK+G+VGRTGAGKSSL+S LFRL E P+  G I +D  +I  LGLK LR+ +++IPQDPVLF GT+R NLDPF+E  D+ +  VL
Sbjct:  357 VSLKRFEEALLLDEMHSE-GLVKSTLRPKAEECG-VFVKKASATWNKEIAIP-TLDGLSFDVPSGCLLGVIGAVGSGKSSLLNAILGELPLSEGSIRVQGRVAYASQQAWVYNSTLRHNILFGKEYDEHRYNDVIKACALDKDFELLSEGDETLVGERGVSLSGGQRARISLARAVYADGDIYLLDDPLSAVDANVGRHLFQECICTYLKDKARILVTHQLQFLKDADEIMVLQQGQCIDKGTYQQLSRNDSGFLSLLAEEVEEETGNESDGDDGSTRFGRPVSKQLSVEEVVRKRAGN------------------VVDSCMSIMSAATTLTLPPE-ETKQEGAVSRQTYAAYLRSFHDLGTGVFLIFLFAMCQVRPVMLMFGDVWLANWANREEVYSMTLASWNASSNTTSPSRPDL----HYYLSVYAALVFGLFVLCLICTMSYYWFTIVASRNLHNGMFHSLIHTNMHFFDNNSIGRILNRFSKDIGVIDDFMPWMLCDVLQIGFSCLGIMCLVAAS--NPVSIAIVLPVICLFFYFRNYFMKSSREMKRIEGINRSPLFGHFSTTLLGIDTIRAYGVEATFTDQFNLFHDAHSRAWYAYLAGQAWLTCRLQALGVVFLLFIVLGLPAL--KDGLSAGTVGLILSYSIMLAKLFEPFVEESAEVENIMTSVERVVEYTSLPPEGEKVTDVIPPP--DWPDKGKITFDNMSFSYHQSLPEVLHNVTCVIKPSEKVGVVGRTGAGKSSLLSTLFRLAE-PK--GLIDIDGINIRKLGLKDLRSKLSIIPQDPVLFSGTMRKNLDPFSEHPDAGLWKVL 1142          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   +  LP KL   ++E GSN SVGQRQL+C+ARA+L+ ++++VIDEATANVD  TD+LIQ+T++  F  CTVLTIAHRL TIM+SDR++V++ G + +FD P+ L   R ++ F  LV+QTG  E K+L  +A
Sbjct: 1147 LKQPVEDLPGKLDEELAEAGSNFSVGQRQLVCLARAILRHSRILVIDEATANVDPRTDALIQETIRDKFQDCTVLTIAHRLHTIMDSDRVMVLDAGRLVEFDAPYKLLKKR-NTIFSGLVEQTGGTEAKRLFDIA 1280          

Query:   56 YEYLSEWEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLS-FCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFE--PSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            +   + W+ E     Q + +PSL++ +     K Y  LGL   F + + + QP ++  L++ F      T  E  +Y+  + +  + ++L   P+ F+    GMR++    A++Y+K+L L++ AL  TT+G +INL+S+D  KF+      FLH++ +GPL      V+L+     A LA + +L+ L P Q+ +G      R   +   DER+K+++E+I GM+V+KMY WE  F K+I  LR+  L +       +  + +  FS +  I         L G  L++  V+  V L N +R      F   IT   + RV+  R +
Sbjct:   35 HSLFNAWDVEIKRYKQEKRRPSLVRALINAFGKGYAALGLFPLFADGLGILQPILLGYLVTYFVEDSPITKKEAYLYAAGVGLCGLFILLFNVPFAFMKNVYGMRVRAACTALIYKKVLHLSRTALASTTTGNLINLVSADAQKFDWVRLAPFLHYLILGPLEVGVVAVLLWYQIGPAALAGVGLLVCLAPMQVKMGNALMSLRGKAIHWMDERVKIMNEIIAGMRVIKMYTWEDSFAKLIMHLRKNELKWFLRMAYIQGAFASFFFSSAGLIYFTTFLVYVLTGEVLTAAKVFTCVSLFNSVRIVCALFFPFAITLFNESRVSLKRFE 363          

Query: 1147 QEFLSLSEFEMNEIS--SSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEI-TEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLIN 3552
            ++FL  +  E+N+IS     + +SK            T    + +W ++      L+ +SF+  A     I G +GSGKS++ M + GELPL+ G I R G L+Y SQ PW+FSG++ +NI F    +   +E+ I    L +DI   P   L+ +G+RGV LSGGQ+AR+SLARA Y  ADI LLDDPL+AVDA VG  +F +CI     +K+ +LVTHQL  LK  + I+VL +G +   GTF +I             D +   ID S+     D++ VS    E +  N N               +I G  A +++        DE E  +  +VKL+LYWKYF  G  A  + L+FI    T    +    WLS+ +    ++ AS +         L+GL LLT    A G+ S+  LF+  + S + LH  M  +IL SPI FF+ N +GRI+NRFSKDI   DD +P+     +      + GL  ++   Y  ++  + + + F  +   Y+  S  ++RLEAV  SP+++H + TL GL  IR+ + +  F ++  + QD  S A  L IS+  W    LD V  +F V+A+ +  A+      +T   G++L+  + +   T + V ++SEVEN+MTS+ER+  Y  LP+E     + L  +  DWP  G + F+++SL Y       L ++ L I  ++K+GI GRTGAGKSSL++ LFR+   P   G++++D  D+ T+ ++  R ++AVI QDPVLF GT+R NLDPF +FTD ++ + +++   +QL+N
Sbjct:  382 EQFLLGTSSEINQISREGETTILSK------------TLTKRWIRWQDDSCT---LQGVSFAAGAGDLVIITGPVGSGKSTLLMTIQGELPLNAGSIRRHGHLAYVSQVPWVFSGTVRENITFGKEYDKAAYEKAIKVCDLAKDINRFPKGDLSCIGQRGVSLSGGQRARVSLARAVYADADIYLLDDPLSAVDAKVGSHLFKECICGALTNKVRILVTHQLQYLKHANSIIVLSDGKIAQKGTFQDI-------------DVSHIGIDVSK-----DSVIVSAAPVEGQQGNHN---------------LIDGVPAVDMA--------DEEEDQAVGSVKLSLYWKYFRAGLPAVVLFLIFIFCIITEASILAPMWWLSYLSEMTPEKQASGSVL--GVYAGLVGLSLLT----ATGMASL--LFIAALRSSENLHNAMTTTILKSPILFFDTNPSGRIMNRFSKDIGTMDDHIPLKFSWTVTLLFHFMGGLLFSAIVEYRLVLSAIPVFVAFLLICWFYLRSSRELQRLEAVRCSPVYSHFTDTLNGLEVIRSSRMEKGFWEQLIRHQDEQSMALSLVISARSWMNNNLDLVSFLF-VSAVAATAAITQQDPAST---GMLLSLAIAMAQGTSYGVEKASEVENEMTSVERVISYTRLPSEPGYSRQTLPCE--DWPERGAVTFRDMSLVYREGTPSALDDITLEITAKQKVGIAGRTGAGKSSLLAALFRM---PEPGGEVLIDGIDLGTIDIQAARRAMAVITQDPVLFGGTLRRNLDPFGKFTDQEIWSAIES---VQLLN 1111          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQT 3899
            L++T+  LPD+L   + E GS  SVG+RQL+C+ARALL+R KV+V+DEATANVD  TD  +Q+ ++S F  CTVLTIAHRL+TIM+ D++IV++ G V ++D P +L + + D  F  L++ +
Sbjct: 1109 LLNTVRALPDQLMYQLGESGSTFSVGERQLLCLARALLQRCKVLVLDEATANVDYRTDRQVQQLIRSRFTGCTVLTIAHRLNTIMDYDKVIVLDKGHVVEYDTPEML-AGKQDGVFAGLLKNS 1230          

Query:  311 RNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            RN      +  GMRLK+ +  ++Y+KIL  ++ +L    +G +INL+S+D  + E  +  L    +GP+  +   V+L +F     L+  + L I++       K + K R    ++TD+R+  +SE+I+G++ VKMY WE  +   +  LRRK +    ++ L  S +VAL    +    +  +      G+ L S  ++  + L+  +  +IV      +   +D  V+  RI+
Sbjct:  147 RNQMELFGLYAGMRLKVALVGLIYKKILNSSRCSLSTVRTGHVINLISNDAKRIELFITNLCLAMLGPVSILVCIVMLCLFVGWQSLSGALFLFIIMLYGQLAAKRFAKLRGKAAAVTDKRLGAMSEVIHGIRAVKMYAWEWNYSDEVKGLRRKEMQIIRLKNLILSTFVALYSVSASIAALISIITLIFSGIHLDSARIFTLINLLKTLEFAIVVHLGACLGTVLDAFVSIRRIE 382          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDS-LIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQ 3830
            L   IN+ P    S + + G +LS GQR  + +ARA+   A + ++D+  + VD    S L ++ +     +   + + H+L  + +++ IIV+++G + Q
Sbjct:  507 LAKDINRFPKGDLSCIGQRGVSLSGGQRARVSLARAVYADADIYLLDDPLSAVDAKVGSHLFKECICGALTNKVRILVTHQLQYLKHANSIIVLSDGKIAQ 607          

Query: 3064 VENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGR-IEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEF 3495
            V +   SI RI +++    +E  ++++E ++ ++    T R I +Q+        D C L+ V+      + + I G  G+GKS+L  L+    E+P + G I             +    +A + Q P +F GT+R N+    E+
Sbjct:  371 VLDAFVSIRRIEQFLLGTSSEINQISREGETTILSKTLTKRWIRWQD--------DSCTLQGVSFAAGAGDLVIITGPVGSGKSTL--LMTIQGELPLNAGSI-------------RRHGHLAYVSQVPWVFSGTVRENITFGKEY 493          

Query: 1147 QEFLSLSEFEMNEIS--SSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGL---ASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLIN 3552
            ++FL  +  E+N IS     + +SK            T    + +W ++      L+ +SF+  A     I G +GSGKS++ M + GELPL+ G I R G L+Y SQ  W+FSG++ +NI F        +E+ I    L +DI   P   L+ +G+RGV LSGGQ+ R+SLARA Y  ADI LLDDPL+AVDA VG  +F +CI     +K+ +LVTHQL  LK  D I+VL +G +   GTF ++             D +   ID S+     D++       D A  +  +    +        +I G  A +++        DE E  +  +V+L+LYWKYF  G SA  ++L+FI    T    +    WLS+ +    ++ AS +         L+GL LLT    A G+ S+  LF+  + S + LH  M  +IL SPI FF+ N  GRI+NRFSKDI   DD +P+    F  +  L+   +G+   ++   Y  ++  + + + F  +   Y+  S  ++RLEAV  SP+++H + TL GL  IR+ + +  F ++  + QD  + A  L IS+ RW    LD +C +F V+A+ +  A++     +T   G++L+  + +   T + V ++SEVEN+MTS+ER+  Y  LP+E     + L  +  DWP  G + F+++SL Y       L ++ L I  ++++GI GRTGAGKS L++ LFRL   P   G++++D  D+ T+ ++  R ++AVI QDPVLF GT+R NLDPF++FTD ++   L++   +QL+N
Sbjct:  382 EQFLLGASSEINRISCEGETTILSK------------TLTKRWIRWQDDSCT---LQGVSFAAGAGDLVIITGPVGSGKSTLLMTIQGELPLNAGSIRRHGHLAYVSQMSWVFSGTVRENITFGKEYGKAAYEKAIKVCDLAKDINRFPKGDLSCIGQRGVSLSGGQRTRVSLARAVYADADIYLLDDPLSAVDAKVGSHLFKECICGALTNKVRILVTHQLQYLKHADSIIVLSDGKIAQKGTFQDM-------------DVSHIGIDVSK-----DSVI------DGAAPVEGQQGHHD--------LIDGAPAVDMA--------DEEEDQAVGSVRLSLYWKYFRAGLSAVVLLLIFIFCVFTEASILAPMWWLSYLSEMTPEKQASGSVL--GVYAGLVGLSLLT----ATGMASL--LFIAALRSSENLHNAMTTTILKSPILFFDTNPFGRIMNRFSKDIGTMDDHIPL---KFSWTVTLLFHFMGVLLFSAIVEYRLVLSAIPVFVDFLLICWFYLRSSRELQRLEAVRCSPVYSHFTDTLTGLEVIRSSRMEKRFWEQLVRHQDEQTMALSLVISARRWMDNNLDLICFLF-VSAVAATAAIIQQDPAST---GMLLSLAIAMAQGTSYGVEKASEVENEMTSVERVISYTRLPSEPGYSRQTLPCE--DWPERGAVTFRDMSLVYREGTPSALDDITLEITAKQRVGIAGRTGAGKSFLLAALFRL---PEPGGEVLIDGVDLGTIDIQAARRAMAVITQDPVLFGGTLRRNLDPFDKFTDQEIWAALES---VQLLN 1111          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQT 3899
            L++T+  LPD+L   + E GS  SVG+RQL+C+ARALL+R KV+V+DEATANVD  TD  +Q+ ++S F  CTVLTIAHRL+TIM+ D++IV++ G V ++D P +L + + D  F  L++ +
Sbjct: 1109 LLNTVRALPDQLMYQLGESGSTFSVGERQLLCLARALLQRCKVLVLDEATANVDYRTDRQVQQLIRSRFTGCTVLTIAHRLNTIMDYDKVIVLDKGHVVEYDTPGML-AGKQDGVFAGLLKNS 1230          

Query:  311 RNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            RN      +  GMRLK+ +  ++Y+KIL  ++ +L    +G +INL+S+D  + E  +       +GP   V   V+L +F     L+  + L I++       K + K R    ++TD R+  VSE+I+G++ +KMY WE  +   I  LRR  +    ++ L  S +VAL    +    +  +      G+ L    ++  + L+  +  +IV   +  +   +D  V+  RI+
Sbjct:  147 RNQMELFGLYAGMRLKVALIGLIYKKILNSSRCSLSTVRTGYVINLISNDAKRIELFISNFSMAILGPFKIVVCIVMLCLFVGWQSLSGALFLFIIMLYGQLAAKQFAKLRGKAAAVTDRRLGAVSEVIHGIRAMKMYAWEWNYSDEIKGLRRLEMQIIRLKNLILSTFVALYSVSASIAALISIITLIFSGIHLDPARIFTVINLLKSLEFAIVVDLAECLREVLDAFVSIRRIE 382          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDS-LIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQ 3830
            L   IN+ P    S + + G +LS GQR  + +ARA+   A + ++D+  + VD    S L ++ +     +   + + H+L  + ++D IIV+++G + Q
Sbjct:  507 LAKDINRFPKGDLSCIGQRGVSLSGGQRTRVSLARAVYADADIYLLDDPLSAVDAKVGSHLFKECICGALTNKVRILVTHQLQYLKHADSIIVLSDGKIAQ 607          

Query: 3061 EVENQMTSIERIYEYI-ALPTEYPKLTKELDSQLIDWPSTGR-IEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEF 3495
            EV +   SI RI +++    +E  +++ E ++ ++    T R I +Q+        D C L+ V+      + + I G  G+GKS+L  L+    E+P + G I             +    +A + Q   +F GT+R N+    E+
Sbjct:  370 EVLDAFVSIRRIEQFLLGASSEINRISCEGETTILSKTLTKRWIRWQD--------DSCTLQGVSFAAGAGDLVIITGPVGSGKSTL--LMTIQGELPLNAGSI-------------RRHGHLAYVSQMSWVFSGTVRENITFGKEY 493          

Query: 1237 KCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNN-QFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLP-VTLQDFILSTCLVLFGLG---LASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGL-IGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSL-YYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            K   VT ++V   WN  +     L  ++  L+      + G +G GK+S+  A+LGEL + KG +   G   Y  Q PW++SG++ +N+LF       +++  + A  L++D+   P+  LT +GE GVLLSGGQ+ RI LARA Y  ADI LLDDPL++VDA VG  IF +C+  + KDK  +LVTHQL  LK  D ++V++ G++   GT+ E+       H  L+ +                                N +    ++V               S    ++  D L      +V   LYW+Y   G     VV+  + +  +    V  D WL    T++ +   ++A  Y      +    LLT++              I + S + LH KM  ++L +P+ FF+ N  GRILNRFS+DI + DDLLP V+L  F     LVL+ +G   L +  N W  +    ++IIF  + R Y+  S  ++RLEA+ RSP+F+H S TL+GL T+R    Q  F K F K QD +SK +F  +S+ RW   RLD +C +F +  +++ +A       +     L L Y + L +  +Q+ VRQ SE EN MTS+ER+  Y  +  E    T        +WP  G ++  NVSL YY G  + VLK+V   I   E++GI GRTGAGKSSL+S LFR+   P   G+I++D  DIS++ ++  R +I+VI QDP+LF G++R NLDPF+++ D ++   L+ +S
Sbjct:  419 KSYHVTMKDVTCFWNGEVAPS--LSHVTLELRNSDLVLVTGPVGCGKTSLLSAILGELSVRKGDLSVNGRAVYVPQCPWVYSGTVRENVLFGKKYQQWKYQVVVRACDLEKDLNEFPDRDLTTIGEHGVLLSGGQRTRIGLARALYADADIYLLDDPLSSVDAKVGRHIFDECVCGILKDKTRVLVTHQLQYLKGADHVVVMNAGSVAFEGTYEEL-----RAHPYLELNLI--------------------------AGPYNVSPPVARSVDSRRLSSASSLMEGDSGGLEVAEEDRLT----GSVSWGLYWEYLMAGARPVAVVIFLVFFVASQACLVLPDWWL-LKVTKLPRHQRNEASNYYTYGILVGAAFLLTVT-------RTFMFLFITLNSSRNLHNKMAATVLRAPVLFFDTNPTGRILNRFSRDIGVMDDLLPSVSLDAF----QLVLYCVGAIILPTVLNPWVTLGAFPMIIIFILISRYYLRTSRELRRLEAINRSPVFSHFSDTLEGLVTVRTHHMQKGFIKAFYKHQDEHSKVWFTLLSALRWLGIRLDLLCVLFTIVVVFAAIA----ADSSAGATALSLIYALQLAVDTSQYGVRQCSETENYMTSVERVIGYTNILPESGYETGARPPS--EWPKKGAVDLVNVSLAYYPGAPE-VLKDVTFSINPAERVGIAGRTGAGKSSLVSALFRM---PDPEGRILIDGLDISSIDIQSSRRAISVISQDPILFTGSLRLNLDPFDKYADEEIWDALEGAS 1132          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQ 3893
            L  TI ++P +L + + E GSNLS G+RQL+C+ARA+L+R  +IV+DEATANVD  TD+LIQ+T+++ F  CTV+TIAHRL+TIM+ D+I+V+  G V ++  P  L  + PD  F  L +
Sbjct: 1133 LKRTILQMPGQLMTQLMECGSNLSAGERQLLCLARAMLQRNNIIVLDEATANVDFKTDALIQETIRTKFKGCTVITIAHRLNTIMDYDKILVLERGRVAEYGTPQELM-EMPDGVFRHLYE 1252          

Query:  341 MGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            M MR +     +++ KIL+L+Q  +   T+G I+NL+S D+ +F+P +  +     G     A T +L        LA I  L+IL+     +G+L    R  I  I DER+ +++ ++ G++ VKMY WE  F   ++++RR+   +  ++    + +    ++     +   +      G+ L +  V++ + L+N IR+++    + G  +  D      RIQ
Sbjct:  171 MAMRWRAATMGLLFNKILRLSQTTINDVTTGYIVNLISGDVQRFDPVVCQMALFVQGLFEIAAVTGLLVYTVGVQSLAGIAFLVILVFYYCGMGRLCVYLRNRIAKIADERLGLMNAVLAGVRTVKMYAWELPFKDRVSRIRRQETYFYRLKAGVLATFQTFLYTCQSIAVFITLLVLIATGVSLDTFNVFMLLALVNTIRSAVSWNIAEGANYLGDFLSALDRIQ 396          

Query: 1303 ILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTG-------------SLSYTSQQPWIFSGSILQNI-LFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEII 1884
            +LKD++FS+   +   I G  G+GKSS+  AL   +P  +G I+  G             ++S  SQ P +F+GS+  N+  F+   + +    +   +L R I  MP +L+T++ E G  LS G++  + LARA  L  + I++ D   A        +  + I   FK   V+ + H+L+ +   DKILVL  G +  +GT  E++
Sbjct: 1035 VLKDVTFSINPAERVGIAGRTGAGKSSLVSALF-RMPDPEGRILIDGLDISSIDIQSSRRAISVISQDPILFTGSLRLNLDPFDKYADEEIWDALEGASLKRTILQMPGQLMTQLMECGSNLSAGERQLLCLARAM-LQRNNIIVLDEATANVDFKTDALIQETIRTKFKGCTVITIAHRLNTIMDYDKILVLERGRVAEYGTPQELM 1240          

Query: 1417 SKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSI---LKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSH-DNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSW-----WTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGG--LLSVI--CLFLICIYSC-KALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVT----LQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSL-YYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQ 3525
            S+G +   G + Y  Q  W+FSG++ +NILF+ P + + +++T+ A  L +DI  +P    T +GERG  LSGGQKAR++LARA Y   DI LLDDPL+AVDA VG  IF  CI+ + ++K+ +LVTHQL  LK+ D I+++  G +   G + ++   G+D+ S+    +Q   +Y                            ++   KEQ +      +   T  + S +  +       +  H   +   LYW+YF  G  A  ++L+ +L+       +  ++WL       W  +  K N                  L+      GG   L++I   L+ I    C + LH+KM+ SIL +P+ F++ N +GRILNRFSKDI I D+ LP T    LQ +IL T   L  + +    NYW+I  ++ +L+ F  + R Y+  S  IKR+EA+++SP+ AH++ TL+G+  IR +  +N F + F + QD  S+ +FL   ++RW   RLD VCT F+  A ++ + LV  +   +   GL L Y +  +G  Q+A+RQ+++VEN MTS+ER+  Y  L  E     ++   +   WP+ G ++F+NVSL YYEG  Q VL N+N+ I+  E++G+ GRTGAGKSSL++ LFR+   P   GKII+D Q+I  L ++  R  I+VI Q+P LF G++R NLDPF+ + D+ +  VL+
Sbjct:  486 SEGSVKTRGEVVYVPQTAWVFSGTVRENILFSKPYDEERYQRTLEACDLAKDIVSLPQGDATILGERGASLSGGQKARVNLARAVYADGDIYLLDDPLSAVDAKVGKHIFENCITGVLENKIRILVTHQLQHLKNADYIMIMDRGAISHEGDYQQVQDSGLDLESLEEEFRQGWEKY----------------------------HQLHDKEQPLSKEKQAVKKATKKDTSDSEPIQGMARKAEERHVGTISAKLYWRYFRSGLHACLLILLVLLFLIAQASIISPNLWLVHMSRMKWVEQKHKLN------------------LIIYGCLVGGALFLAIIRGLLYYITTLRCSENLHDKMVVSILKTPVHFYDTNPSGRILNRFSKDIGIVDEFLPPTSLLALQ-YILQT---LASVCVTCSTNYWAIFGVVPMLLGFIGINRYYLKTSREIKRMEAISQSPVLAHLADTLEGIVLIRTYHMENRFIQRFNEVQDHRSQIWFLVPHTARWMGIRLDFVCTAFVAIATFTGI-LVLMQMCFSGTLGLSLVYAISTVGQLQFAMRQTADVENMMTSVERVMSYTHLDEEPGYYIEKKAPE--SWPAHGNVKFENVSLRYYEGGPQ-VLHNLNIDIKGGERVGVAGRTGAGKSSLVAALFRM---PDPEGKIIIDDQEIGQLNIQNTRRVISVITQNPTLFSGSLRINLDPFSRYDDAALWNVLE 1151          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPA 3908
            + D + +LP +LY  +SE G+N  VG+RQL+C+ARALL + K+IV+DEATANVD +TD  IQ+T++S F+ CTV+TIAHRL+TI++ D+++V+  G   +FD P  L   R D    +L +    A
Sbjct: 1155 MKDKVKELPGELYFELSESGNNFGVGERQLLCLARALLNKNKIIVMDEATANVDFNTDRSIQETIRSKFSGCTVITIAHRLNTILDYDKVLVMEKGQAMEFDSPDELLK-RGDGMLTELFRNQSAA 1279          

Query:  341 MGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAK-----SLWVALRFSGSRFI-IIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            +GMR +     I+Y K+L+++Q  L + +SG +INL+S+DI + + + Q L      P   V   V+L++      +  +   LILIP +  +     K R     +TD R+++++E+I+G++ VKMY WE  +  V+ ++RR    YG V  + K     S + +L+ +    I +IA++   F  G  L+   ++  V L+++ R S+V   + G+    D   +  RI+
Sbjct:  167 LGMRFRAAATGILYNKVLRMSQSKLAKISSGHVINLVSNDIQRLDLATQNLFASLRSPFDLVVLGVLLWVLIGWQAVTGLAFALILIPYEAEMTGWVAKLRMQAARVTDRRLEVMNEVISGIRAVKMYAWEWPYRDVVRQIRR----YGPVLIMRKIYGILSSFASLQHTYDSVICLIAFITLVF-TGTRLTPYNIFTMVGLLSENRRSLVYGLTDGMQLIADCFASLDRIE 393          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-------DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            QEFL L     +EI+   S     LP +  K +SV  +N+   W++N+ +   L+++SF+LK+ Q  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y +QQPW+F G+I  NILF    + Q ++  I A AL RD+E++P    T +G+RG  LSGGQKAR++LARA Y  AD+ LLDDPL+AVDA VG  +F +CI  + K K  +LVTHQL  L   D+IL+L EG+M+A GT+ E++  G+D  S+LK++  E         F+     +S+I+    T+        +Q        +  ET   V            E      + + LY KY   G +   ++ + +L       Y+  D WL++W  E +K N  ++            D    +G+   LT ST   G +  + LF + +   +ALH +M +SIL +P++FF+ N  GR+LNRFSKDI   D LLP+T  DF+     +L  + +A+    W +I ++ LL++F  LRR ++  S  +KRLE  TRSP+F+H+S++LQGL TIRAF ++  F++EF   QD +S A+FL++++SRWFA RLD +C +FI    +    L+   ++     GL L Y V L+G+ QW VRQS+EVEN MTS+ER+ EY  L +E P  T++      DWPS G + F  VS  Y    Q VL N+  +   +EK+GIVGRTGAGKSSL+S LFRL E P+  GKI +D    S +GL  LR  +++IPQDPVLF GT+R NLDPF++ +D  +   L   S
Sbjct:  384 QEFLLL-----DEITKGGS----ALPPEDKKENSVELQNLTCYWDKNL-DAPTLQNVSFTLKSNQLLAVIGPVGAGKSSLLSAILGELPAEKGVLKVKGQMTYAAQQPWVFPGTIRSNILFGKDFDQQKYDMVIKACALKRDLELLPGGDQTVIGDRGATLSGGQKARVNLARAVYQEADVYLLDDPLSAVDAEVGRHLFEKCICGVLKKKPRVLVTHQLQYLTEADQILILKEGHMVAKGTYTELLQSGLDFASLLKKEEEEEEQQLLPKDFSIRERSLSQISALSQTSSVQSVKDGDQ--------LPAETVQMVPE----------ESRGQGTIGIKLYLKYLRAGANVAVLLFVILLNILAQVSYIMQDWWLAYWAAEQEKLNLKNSSIPNGPNATEELDLNLYLGVYAGLTASTIIFGFMRNLLLFNVLVRCAQALHNRMFNSILKTPVRFFDINPIGRVLNRFSKDIGQLDSLLPLTFVDFVQVFLQILGVVAVAASVIPWILIPVVPLLLVFIFLRRYFLKTSREVKRLEGTTRSPVFSHLSSSLQGLWTIRAFGAEERFQREFDAHQDLHSGAWFLFLTTSRWFAVRLDGICAIFITITTFGI--LLLRNQLEAGSVGLALTYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTDLQSEAPWETQKRPPP--DWPSKGLVTFDQVSFTYSEDSQPVLHNLKAVFRPQEKVGIVGRTGAGKSSLVSALFRLAE-PQ--GKIYIDGVVTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFHQHSDEALWNALDEVS 1153          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G +  F  P +L  D PD  F ++VQQTG  E   L + A
Sbjct: 1181 LKSAVEELPQKLETQLAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKTIREKFRECTVLTIAHRLNTIIDSDRILVLDAGRIWAFAEPLVLLQD-PDGIFFKMVQQTGKQEAAALHQAA 1314          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN----ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W++E     +    PSL K + R  WK Y  LG     E  I + QP ++ K++ +  + +    +   E L Y+  L +    L L+ + Y++   + GM++++ +  ++Y+K L L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W+ PL       +L+M    + LA ++VL+ L+PTQ   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  +++ +R K +         + L +A  F  S+ I+        L+G  +S+  V++TV L   +R ++   F   I    + RV+  RIQ
Sbjct:   61 WDQEVVNASKEMQTPSLAKAMIRCYWKSYSVLGFFTLLEEIIKVVQPVVLGKIIEYFESYDPDNAKAFHETLGYAAGLSILTFGLALLHHLYFYHVQRAGMKIRVAMCHMIYQKALSLSNSAMGKTTTGQIVNLLSNDVNKFDEVTIFLHFLWVAPLQAAVVVGLLWMEIGPSCLAGMVVLMFLMPTQTLFGRLFSKFRSKTAALTDNRIRTMNEVVSGIRIIKMYAWEKPFAALVSDVRNKEISKIMKSSYLRGLNMASFFCASKIILFVTFTLYVLLGNTISASRVFVTVSLYTAVRLTVTLFFPSAIEKLFESRVSIRRIQ 384          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-------DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            QEFL L     +EI+   S     LP +  K +SV  +N+   W++N+ +   L+++SF+LK+ Q  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y +QQPW+F G+I  NILF    + Q ++  I A AL RD+E++P    T +G+RG  LSGGQKAR++LARA Y  AD+ LLDDPL+AVDA VG  +F +CI  + K K  +LVTHQL  L   D+IL+L EG+M+A GT+ E++  G+D  S+LK++  E         F+     +S+I+    T+        +Q        +  ET   V            E      + + LY KY   G +   ++ + +L       Y+  D WL++W  E +K N  ++            D    +G+   LT ST   G +  + LF + +   +ALH +M +SIL +P++FF+ N  GR+LNRFSKDI   D LLP+T  DF+     +L  + +A+    W +I ++ LL++F  LRR ++  S  +KRLE  TRSP+F+H+S++LQGL TIRAF ++  F++EF   QD +S A+FL++++SRWFA RLD +C +FI    +    L+   ++     GL L Y V L+G+ QW VRQS+EVEN M S+ER+ EY  L +E P  T++      DWPS G + F  VS  Y    Q VL N+  +   +EK+GIVGRTGAGKSSL+S LFRL E P+  GKI +D    S +GL  LR  +++IPQDPVLF GT+R NLDPF++ +D  +   L   S
Sbjct:  384 QEFLLL-----DEITKGGS----ALPPEDKKENSVELQNLTCYWDKNL-DAPTLQNVSFTLKSNQLLAVIGPVGAGKSSLLSAILGELPAEKGVLKVKGQMTYAAQQPWVFPGTIRSNILFGKDFDQQKYDMVIKACALKRDLELLPGGDQTVIGDRGATLSGGQKARVNLARAVYQEADVYLLDDPLSAVDAEVGRHLFEKCICGVLKKKPRVLVTHQLQYLTEADQILILKEGHMVAKGTYTELLQSGLDFASLLKKEEEEEEQQLLPKDFSIRERSLSQISALSQTSSVQSVKDGDQ--------LPAETVQMVPE----------ESRGQGTIGIKLYLKYLRAGANVAVLLFVILLNILAQVSYIMQDWWLAYWAAEQEKLNLKNSSIPNGPNATEELDLNLYLGVYAGLTASTIIFGFMRNLLLFNVLVRCAQALHNRMFNSILKTPVRFFDINPIGRVLNRFSKDIGQLDSLLPLTFVDFVQVFLQILGVVAVAASVIPWILIPVVPLLLVFIFLRRYFLKTSREVKRLEGTTRSPVFSHLSSSLQGLWTIRAFGAEERFQREFDAHQDLHSGAWFLFLTTSRWFAVRLDGICAIFITITTFGI--LLLRNQLEAGSVGLALTYAVTLMGMFQWGVRQSAEVENMMISVERVVEYSDLKSEAPWETQKRPPP--DWPSKGLVTFDQVSFTYSEDSQPVLHNLKAVFRPQEKVGIVGRTGAGKSSLVSALFRLAE-PQ--GKIYIDGVVTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFHQHSDEALWNALDEVS 1153          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G +  F  P +L  D PD  F ++VQQTG  E   L + A
Sbjct: 1181 LKSAVEELPQKLETQLAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKTIREKFRECTVLTIAHRLNTIIDSDRILVLDAGRIWAFAEPLVLLQD-PDGIFFKMVQQTGKQEAAALHQAA 1314          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN----ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W++E     +    PSL K + R  WK Y  LG     E  I + QP ++ K++ +  + +    +   E L Y+  L +    L L+ + Y++   + GM++++ +  ++Y+K L L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W+ PL       +L+M    + LA ++VL+ L+PTQ   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  +++ +R K +         + L +A  F  S+ I+        L+G  +S+  V++TV L   +R ++   F   I    + RV+  RIQ
Sbjct:   61 WDQEVVNASKEMQTPSLAKAMIRCYWKSYSVLGFFTLLEEIIKVVQPVVLGKIIEYFESYDPDNAKAFHETLGYAAGLSILTFGLALLHHLYFYHVQRAGMKIRVAMCHMIYQKALSLSNSAMGKTTTGQIVNLLSNDVNKFDEVTIFLHFLWVAPLQAAVVVGLLWMEIGPSCLAGMVVLMFLMPTQTLFGRLFSKFRSKTAALTDNRIRTMNEVVSGIRIIKMYAWEKPFAALVSDVRNKEISKIMKSSYLRGLNMASFFCASKIILFVTFTLYVLLGNTISASRVFVTVSLYTAVRLTVTLFFPSAIEKLFESRVSIRRIQ 384          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-------DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            QEFL L     +EI+   S     LP +  K +SV  +N+   W++N+ +   L+++SF+LK+ Q  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y +QQPW+F G+I  NILF    + Q ++  I A AL RD+E++P    T +G+RG  LSGGQKAR++LARA Y  AD+ LLDDPL+AVDA VG  +F +CI  + K K  +LVTHQL  L   D+IL+L EG+M+A GT+ E++  G+D  S+LK++  E         F+     +S+I+    T+        +Q        +  ET   V            E      + + LY KY   G +   ++ + +L       Y+  D WL++W  E +K N  ++            D    +G+   LT ST   G +  + LF + +   +ALH +M +SIL +P++FF+ N  GR+LNRFSKDI   D LLP+T  DFI     +L  + +A+    W +I +L LL++F  LRR ++  S  +KRLE  TRSP+F+H+S++LQGL TIRAF ++  F++EF   QD +S A+FL+I+++RW A  LD +C +FI    +    L+   +++    GL L Y V L+G+ QW VRQS+EVEN M S+ER+ EY  L +E P  T++      DWPS G + F  VS  Y    Q VL N+  +   +EK+GIVGRTGAGKSSL+S LFRL E P+  GKI +D    S +GL  LR  +++IPQDPVLF GT+R NLDPF++ +D  +   L   S
Sbjct:  384 QEFLLL-----DEITKGGS----ALPPEDKKENSVELQNLTCYWDKNL-DAPTLQNVSFTLKSNQLLAVIGPVGAGKSSLLSAILGELPAEKGVLKVKGQMTYAAQQPWVFPGTIRSNILFGKDFDQQKYDMVIKACALKRDLELLPGGDQTVIGDRGATLSGGQKARVNLARAVYQEADVYLLDDPLSAVDAEVGRHLFEKCICGVLKKKPRVLVTHQLQYLTEADQILILKEGHMVAKGTYTELLQSGLDFASLLKKEEEEEEQQLLPKDFSIRERSLSQISALSQTSSVQSVKDGDQ--------LPAETVQMVPE----------ESRGQGTIGIKLYLKYLRAGANVAVLLFVILLNILAQVSYIMQDWWLAYWAAEQEKLNLKNSSIPNGPNATEELDLNLYLGVYAGLTASTIVFGFMRNLLLFNVLVRCAQALHNRMFNSILKTPVRFFDINPIGRVLNRFSKDIGQLDSLLPLTFVDFIQVFLQILGVVAVAASVIPWILIPMLPLLLVFIFLRRYFLKTSREVKRLEGTTRSPVFSHLSSSLQGLWTIRAFGAEERFQREFDAHQDLHSGAWFLFITTARWLAVWLDGICAIFITITTFGV--LLLRNQLDAGSVGLALTYAVTLMGMFQWGVRQSAEVENMMISVERVVEYSDLKSEAPWETQKRPPP--DWPSKGLVTFDQVSFTYSEDSQPVLHNLKAVFRPQEKVGIVGRTGAGKSSLVSALFRLAE-PQ--GKIYIDGVVTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFHQHSDEALWNALDEVS 1153          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G +  F  P +L  D PD  F ++VQQTG  E   L + A
Sbjct: 1181 LKSAVEELPQKLETQLAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKTIREKFRECTVLTIAHRLNTIIDSDRILVLDAGRIWAFAEPLVLLQD-PDGIFFKMVQQTGKQEAAALHQAA 1314          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN----ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W++E     +    PSL K + R  WK Y  LG     E  I + QP ++ K++ +  + +    +   E L Y+  L +    L L+ + Y++   + GM++++ +  ++Y+K L L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W+ PL       +L+M    + LA ++VL+ L+PTQ   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  +++ +R K +         + L +A  F  S+ I+        L+G  +S+  V++TV L   +R ++   F   I    + RV+  RIQ
Sbjct:   61 WDQEVVNASKEMQTPSLAKAMIRCYWKSYSVLGFFTLLEEIIKVVQPVVLGKIIEYFESYDPDNAKAFHETLGYAAGLSILTFGLALLHHLYFYHVQRAGMKIRVAMCHMIYQKALSLSNSAMGKTTTGQIVNLLSNDVNKFDEVTIFLHFLWVAPLQAAVVVGLLWMEIGPSCLAGMVVLMFLMPTQTLFGRLFSKFRSKTAALTDNRIRTMNEVVSGIRIIKMYAWEKPFAALVSDVRNKEISKIMKSSYLRGLNMASFFCASKIILFVTFTLYVLLGNTISASRVFVTVSLYTAVRLTVTLFFPSAIEKLFESRVSIRRIQ 384          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-------DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            QEFL L     +EI+   S     LP +  K +SV  +N+   W++N+ +   L+++SF+LK+ Q  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y +QQPW+F G+I  NILF    + Q ++  I A AL RD+E++P    T +G+RG  LSGGQKAR++LARA Y  AD+ LLDDPL+AVDA VG  +F +CI  + K K  +LVTHQL  L   D+IL+L EG+M+A GT+ E++  G+D  S+LK++  E         F+     +S+I+    T+        +Q        +  ET   V            E      + + LY KY   G +   ++ + +L       Y+  D WL++W  E +K N  ++            D    +G+   LT ST   G +  + LF + +   +ALH +M +SIL +P++FF+ N  GR+LNRFSKDI   D LLP+T  DFI     +L  + +A+    W +I +L LL++F  LRR ++  S  +KRLE  TRSP+F+H+S++LQGL TIRAF ++  F++EF   QD +S A+FL+I+++RW A  LD +C +FI    +    L+   +++    GL L Y V L+G+ QW VRQS+EVEN M S+ER+ EY  L +E P  T++      DWPS G + F  VS  Y    Q VL N+  +   +EK+GIVGRTGAGKSSL+S LFRL E P+  GKI +D    S +GL  LR  +++IPQDPVLF GT+R NLDPF++ +D  +   L   S
Sbjct:  384 QEFLLL-----DEITKGGS----ALPPEDKKENSVELQNLTCYWDKNL-DAPTLQNVSFTLKSNQLLAVIGPVGAGKSSLLSAILGELPAEKGVLKVKGQMTYAAQQPWVFPGTIRSNILFGKDFDQQKYDMVIKACALKRDLELLPGGDQTVIGDRGATLSGGQKARVNLARAVYQEADVYLLDDPLSAVDAEVGRHLFEKCICGVLKKKPRVLVTHQLQYLTEADQILILKEGHMVAKGTYTELLQSGLDFASLLKKEEEEEEQQLLPKDFSIRERSLSQISALSQTSSVQSVKDGDQ--------LPAETVQMVPE----------ESRGQGTIGIKLYLKYLRAGANVAVLLFVILLNILAQVSYIMQDWWLAYWAAEQEKLNLKNSSIPNGPNATEELDLNLYLGVYAGLTASTIIFGFMRNLLLFNVLVRCAQALHNRMFNSILKTPVRFFDINPIGRVLNRFSKDIGQLDSLLPLTFVDFIQVFLQILGVVAVAASVIPWILIPMLPLLLVFIFLRRYFLKTSREVKRLEGTTRSPVFSHLSSSLQGLWTIRAFGAEERFQREFDAHQDLHSGAWFLFITTARWLAVWLDGICAIFITITTFGV--LLLRNQLDAGSVGLALTYAVTLMGMFQWGVRQSAEVENMMISVERVVEYSDLKSEAPWETQKRPPP--DWPSKGLVTFDQVSFTYSEDSQPVLHNLKAVFRPQEKVGIVGRTGAGKSSLVSALFRLAE-PQ--GKIYIDGVVTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFHQHSDEALWNALDEVS 1153          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G +  F  P +L  D PD  F ++VQQTG  E   L + A
Sbjct: 1181 LKSAVEELPQKLETQLAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKTIREKFRECTVLTIAHRLNTIIDSDRILVLDAGRIWAFAEPLVLLQD-PDGIFFKMVQQTGKQEAAALHQAA 1314          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN----ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W++E     +    PSL K + R  WK Y  LG     E  I + QP ++ K++ +  + +    +   E L Y+  L +    L L+ + Y++   + GM++++ +  ++Y+K L L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W+ PL       +L+M    + LA ++VL+ L+PTQ   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  +++ +R K +         + L +A  F  S+ I+        L+G  +S+  V++TV L   +R ++   F   I    + RV+  RIQ
Sbjct:   61 WDQEVVNASKEMQTPSLAKAMIRCYWKSYSVLGFFTLLEEIIKVVQPVVLGKIIEYFESYDPDNAKAFHETLGYAAGLSILTFGLALLHHLYFYHVQRAGMKIRVAMCHMIYQKALSLSNSAMGKTTTGQIVNLLSNDVNKFDEVTIFLHFLWVAPLQAAVVVGLLWMEIGPSCLAGMVVLMFLMPTQTLFGRLFSKFRSKTAALTDNRIRTMNEVVSGIRIIKMYAWEKPFAALVSDVRNKEISKIMKSSYLRGLNMASFFCASKIILFVTFTLYVLLGNTISASRVFVTVSLYTAVRLTVTLFFPSAIEKLFESRVSIRRIQ 384          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQ-FEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKN-------DKPFLIGLIL-LTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            QEFL L     +EI+   S     LP +  K +SV  +N+   W++N+ +   L+++SF+LK+ Q  A+IG +G+GKSS+  A+LGELP  KG +   G ++Y +QQPW+F G+I  NILF    + Q ++  I A AL RD+E++P    T +G+RG  LSGGQKAR++LARA Y  AD+ LLDDPL+AVDA VG  +F +CI  + K K  +LVTHQL  L   D+IL+L EG+M+A GT+ E++  G+D  S+LK++  E         F+     +S+I+    T+        +Q        +  ET   V            E      + + LY KY   G +   ++ + +L       Y+  D WL++W  E +K N  +             D    +G+   LT ST   G +  + LF + +   +ALH +M +SIL +P++FF+ N  GR+LNRFSKDI   D LLP+T  DFI     +L  + +A+    W +I +L LL++F  LRR ++  S  +KRLE  TRSP+F+H+S++LQGL TIRAF ++  F++EF   QD +S A+FL+I+++RW A  LD +C +FI    +    L+   +++    GL L Y V L+G+ QW VRQS+EVEN M S+ER+ EY  L +E P  T++      DWPS G + F  VS  Y    Q VL N+  +   +EK+GIVGRTGAGKSSL+S LFRL E P+  GKI +D    S +GL  LR  +++IPQDPVLF GT+R NLDPF++ +D  +   L   S
Sbjct:  384 QEFLLL-----DEITKGGS----ALPPEDKKENSVELQNLTCYWDKNL-DAPTLQNVSFTLKSNQLLAVIGPVGAGKSSLLSAILGELPAEKGVLKVKGQMTYAAQQPWVFPGTIRSNILFGKDFDQQKYDMVIKACALKRDLELLPGGDQTVIGDRGATLSGGQKARVNLARAVYQEADVYLLDDPLSAVDAEVGRHLFEKCICGVLKKKPRVLVTHQLQYLTEADQILILKEGHMVAKGTYTELLQSGLDFASLLKKEEEEEEQQLLPKDFSIRERSLSQISALSQTSSVQSVKDGDQ--------LPAETVQMVPE----------ESRGQGTIGIKLYLKYLRAGANVAVLLFVILLNILAQVSYIMQDWWLAYWAAEQEKLNPKNNSIPNGPNATEELDLNLYLGVYAGLTASTIVFGFMRNLLLFNVLVRCAQALHNRMFNSILKTPVRFFDINPIGRVLNRFSKDIGQLDSLLPLTFVDFIQVFLQILGVVAVAASVIPWILIPMLPLLLVFIFLRRYFLKTSREVKRLEGTTRSPVFSHLSSSLQGLWTIRAFGAEERFQREFDAHQDLHSGAWFLFITTARWLAVWLDGICAIFITITTFGV--LLLRNQLDAGSVGLALTYAVTLMGMFQWGVRQSAEVENMMISVERVVEYSDLKSEAPWETQKRPPP--DWPSKGLVTFDQVSFTYSEDSQPVLHNLKAVFRPQEKVGIVGRTGAGKSSLVSALFRLAE-PQ--GKIYIDGVVTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFHQHSDEALWNALDEVS 1153          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            L   + +LP KL + ++E GSN SVGQRQL+C+ARA+L++ ++++IDEATANVD  TD LIQKT++  F  CTVLTIAHRL+TI++SDRI+V++ G +  F  P +L  D PD  F ++VQQTG  E   L + A
Sbjct: 1181 LKSAVEELPQKLETQLAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPRTDELIQKTIREKFRECTVLTIAHRLNTIIDSDRILVLDAGRIRAFAEPLVLLQD-PDGIFFKMVQQTGKQEAAALHEAA 1314          

Query:   74 WEKE-----QRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTIN----ETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            W++E     +    PSL K + R  WK Y  LG     E  I + QP ++ K++ +  + +    +   E L Y+  L +    L L+ + Y++   + GM++++ +  ++Y+K L L+  A+G+TT+GQI+NL+S+D++KF+    FLHF+W+ PL       +L+M    + LA ++VL+ L+PTQ   G+L+ KFR    ++TD RI+ ++E+++G++++KMY WE  F  +++ +R K +         + L +A  F  S+ I+        L+G  +S+  V++TV L   +R ++   F   I    + RV+  RIQ
Sbjct:   61 WDQEVVNASKEMQTPSLAKAMIRCYWKSYSVLGFFTLLEEIIKVVQPVVLGKIIEYFESYDPDNAKAFHETLGYAAGLSILTFGLALLHHLYFYHVQRAGMKIRVAMCHMIYQKALSLSNSAMGKTTTGQIVNLLSNDVNKFDEVTIFLHFLWVAPLQAAVVVGLLWMEIGPSCLAGMVVLMFLMPTQTLFGRLFSKFRSKTAALTDNRIRTMNEVVSGIRIIKMYAWEKPFAALVSDVRNKEISKIMKSSYLRGLNMASFFCASKIILFVTFTLYVLLGNTISASRVFVTVSLYTAVRLTVTLFFPSAIEKLFESRVSIRRIQ 384          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLINFL 3558
            QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT   +  IN L
Sbjct:  329 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTVELMDTINKL 1132          

Query:   59 EYLSEWEKEQRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKL 802
            ++ +EWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLR    +   ++ L
Sbjct:   59 KFQNEWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRSSIYMLSIIKSL 306          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA
Sbjct: 1125 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 1259          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLINFL 3558
            QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT   +  IN L
Sbjct:  285 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTVELMDTINKL 1088          

Query:   59 EYLSEWEKEQRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKM 721
            ++ +EWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQ +++
Sbjct:   59 KFQNEWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQEIRV 279          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA
Sbjct: 1081 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 1215          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLINFL 3558
            QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT   +  IN L
Sbjct:  378 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTVELMDTINKL 1181          

Query:   59 EYLSEWEKEQRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            ++ +EWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ
Sbjct:   59 KFQNEWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 378          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA
Sbjct: 1174 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 1308          

Query: 1147 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISELFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSSWIQLINFL 3558
            QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQT   +  IN L
Sbjct:  409 QEFLSLSEFEMNEISSSVSFISKPLPLDIDKCSSVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAIIGEIGSGKSSIFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNNQFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYLGADIILLDDPLAAVDAAVGHQIFTQCISELFKDKLVLLVTHQLHLLKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAIYVSEITEDRATNLNNRNSSKEQTVPLLSPVITGETASNVSSACNLSSRDELEQFSHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWTTEMDKRNASDAEFYKNDKPFLIGLILLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSIIIILFLLIIFWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVCTVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSLYYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTVELMDTINKL 1212          

Query:   59 EYLSEWEKEQRRNKPSLIKCVCRIIWKEYXXXXXXXXXENCINLSQPFIIWKLLSFCNTINETLTEXXXXXXXXXXXXXXXXXXRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 1018
            ++ +EWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ
Sbjct:   90 KFQNEWEKEQRRNKPSLIKCVCRIIWKEYFFLGLLLFFENCINLSQPFIIWKLLSFCNTINETLTEVLIYSTLLIVTIILLVLIRNPYYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGLPLSSQLVWLTVILINQIRASIVDRFSLGITHAIDLRVTFSRIQ 409          

Query: 3531 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 3935
            LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA
Sbjct: 1205 LMDTINKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQTGPAEEKKLRKMA 1339          

Query: 1246 SVTFENVFAKWNENMTNEYILKDISFSLKAPQTCAXXXXXXXXXXXXFMALLGELPLSKGHIMRTGSLSYTSQQPWIFSGSILQNILFNLPKNN-QFEQTITATALDRDIEIMPNELLTRVGERGVLLSGGQKARISLARAAYXXXXXXXXXXXXXXXXXXXXHQIFTQCISE--LFKDKXXXXXXXXXXXXKSVDKILVLHEGNMIAFGTFNEIISQGVDVHSILKQDTTEYVIDKSRTTFNEDAI------------YVSEITEDRATNLNNRNSSKEQ---TVPLLSPVITGETASNVSSACNLSSRDELEQF------------------SHDNVKLNLYWKYFTVGCSAFFVVLMFILYATTMTLYVFTDIWLSWWT-------------TEMDKRNASDAEF------YKNDKPFLIGLI-LLTLSTFAGGLLSVICLFLICIYSCKALHEKMLHSILFSPIKFFNENSAGRILNRFSKDISIADDLLPVTLQDFILSTCLVLFGLGLASYKNYWSXXXXXXXXXXXWALRRSYMNVSTSIKRLEAVTRSPLFAHISTTLQGLTTIRAFKSQNWFRKEFQKKQDRYSKAFFLYISSSRWFAFRLDEVC-TVFIVTAIYSCVALVYHKKINTSDFGLVLNYVVGLIGLTQWAVRQSSEVENQMTSIERIYEYIALPTEYPKLTKELDSQLIDWPSTGRIEFQNVSL-YYEGPDQCVLKNVNLMIEDREKIGIVGRTGAGKSSLISLLFRLVEIPRDCGKIIVDRQDISTLGLKKLRTSIAVIPQDPVLFMGTIRTNLDPFNEFTDSDVCTVLQTSS 3534
            + T +N   KW ++ T E +LK+I+ +       AI+G +G GKSSI  ALLGE+   +G++   GS++Y  QQ WI + +I  NI+F LP +  ++++ I A  L+RD EI+ +   T +GE+G+ LSGGQK R+SLARA Y  +++ LLDDPL+AVD+ VG  +    IS   +      +LVTH L +L   D+I+V++ G +   GT++++I       + +     + +   +   F+ D +              SEI +  A  +++ + S+E+   ++  L   +  + A+      N   ++EL++F                     NVK+ +Y  Y       +    + +L+ TT    + +++WL  W+              E+   N+S  +        ++ +   +G+  +         L S +      I S  +LH+ +L+ +L  P+  F     GRI+NRFS D++    +LP  +  F+++T   +    + +  N W II +  ++  +  ++R Y++ S  +KRLE+V +SP+++H   TLQG+++IRA+   + F +    K D+   +++    S+RW A  L+ V  ++  + A+++ ++L     IN    GL ++Y + +     W VR SSEVE+ + S+ERI EY  +P E P    E      +WP  G I+F N S  Y EG D  VLKN+N +I  REK+GIVGRTG+GKSSL+  LFR++E  +  G+I++D   I  LGL  +R  + +IPQDPVLF GT+R NLDPFN+  D ++  VL+ S+
Sbjct:  690 AATIKNGIFKW-DSTTPEPVLKNINITFPERHLVAIVGPVGCGKSSILSALLGEIDKLEGYVNMKGSIAYVPQQAWIINATIRDNIIFGLPYDACKYQRIIKACCLERDFEILNDADFTEIGEKGINLSGGQKQRVSLARACYSDSNVYLLDDPLSAVDSHVGKDLIDNVISSTGILNGNTRILVTHNLAILSKCDRIIVMNNGMVSEEGTYSDLIRHAGAFANFIATHLADELQATNNQNFSFDELEEKDLLLQDLQRTYSEINQSNANMISSLSKSREKIYKSMENLKMDLEKDVANITKLEDNKRCQEELDKFLKPGAQKNGNKLIEEETSKEGNVKMAVYMAYLR-SIGFWLAAGIILLFVTTQGFSLGSNLWLVRWSDQSKIAANLSKELKELIAHNSSQKQIDDLRKIIRDQRDLNLGIYGVFGFCQALIQLFSSLFFAFAIIKSAASLHKLLLNGVLRCPMSMFETVPVGRIINRFSSDLNAVGTMLPHFINGFLVTTLQAIVVFIMVTIPNPWIIIPLSLMIAFYILIQRVYVSTSRQLKRLESVVKSPIYSHFGETLQGVSSIRAYSLCDKFIESNDNKVDKNLYSYYANTVSNRWLAIILETVGNSIVFMAALFAVISLQNGTGINAGLVGLSVSYALSITQTLNWLVRMSSEVESNIVSVERIEEYSQMPPEAPWDISEKKPDE-NWP-VGCIKFVNYSTKYREGLDN-VLKNINFIINPREKVGIVGRTGSGKSSLVLALFRILE--KSDGEILIDGLPIHELGLHDVRGRLTIIPQDPVLFSGTLRRNLDPFNKHGDEEIWKVLEMSN 1503          

Query: 3543 INKLPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDSLIQKTLQSTFAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQFDHPHLLFSDRPDSTFIQLVQQT 3899
            +N   ++L   +SEGG NLSVGQRQL+C+ARALL+R  ++V+DEATA VDL TD LIQ+T++  F  CT+LTIAHRL+T+++ D+I+V+ NG + + D P+ L  + P+S F  + + +
Sbjct: 1509 VNSGNEQLEMVISEGGENLSVGQRQLVCLARALLRRTNILVLDEATAAVDLDTDVLIQETIRREFKECTILTIAHRLNTVLDYDQILVLENGEIIEMDAPNNLLKN-PESQFYSMAKSS 1626          

Query:  320 YYFLTMKMGMRLKIGIGAIVYEKILKLNQKALGQTTSGQIINLMSSDIHKFEPSLQFLHFIWIGPLVTVATTVILYMFSREAGLASIMVLLILIPTQISLGKLYFKFRFLILSITDERIKMVSELINGMQVVKMYCWEPMFIKVIAKLRRKTLLYGFVRKLAKSLWVALRFSGSRFIIIAYMCCAFLVGL 889
            Y+ +  K+GMR++  + + VY K L+L+  +  ++T G+I+NLMS D  KF   + ++H IW GP   +A  ++L+     + LA ++++L++IP    +G +  K +   + +TD RIKM++E++NG++V+K+Y WEP FI  + ++R K L +    K A     A+ F+        + C  FLV L
Sbjct:  435 YFHIVFKIGMRVRSSLISAVYRKSLRLSTASRKESTVGEIVNLMSIDAQKFLELISYIHMIWSGPYQIIAALILLWYELGPSVLAGLVIMLLMIPVNAVIGNITRKIQAQQIKVTDSRIKMMNEILNGIKVLKLYAWEPSFINFVTEIRNKELKF---MKRAAYYNAAISFT--------FNCAPFLVSL 613          

Query: 3552 LPDKLYSPVSEGGSNLSVGQRQLICMARALLKRAKVIVIDEATANVDLHTDS-LIQKTLQST--FAHCTVLTIAHRLSTIMNSDRIIVINNGIVDQ 3830
            L D  ++ + E G NLS GQ+Q + +ARA    + V ++D+  + VD H    LI   + ST      T + + H L+ +   DRIIV+NNG+V +
Sbjct:  801 LNDADFTEIGEKGINLSGGQKQRVSLARACYSDSNVYLLDDPLSAVDSHVGKDLIDNVISSTGILNGNTRILVTHNLAILSKCDRIIVMNNGMVSE 896