Endoglin CD105 antigen

Overview
NameEndoglin CD105 antigen
Smed IDSMED30033385
Length (bp)4055
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endoglin CD105 antigen (SMED30033385) t-SNE clustered cells

Violin plots show distribution of expression levels for Endoglin CD105 antigen (SMED30033385) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endoglin CD105 antigen (SMED30033385) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endoglin CD105 antigen (SMED30033385) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033385

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30033385h1SMcG0018920 SmedASXL_016217SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30033385h1SMcG0018920 dd_Smed_v4_17373_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033385h1SMcG0018920 dd_Smed_v4_17373_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30033385h1SMcG0018920 dd_Smed_v4_17373_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30033385h1SMcG0018920 dd_Smed_v6_17373_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30033385h1SMcG0018920 OX_Smed_1.0.13155ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 108.227 bits (269), Expect = 1.669e-24
Identity = 45/87 (51.72%), Postives = 59/87 (67.82%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +   E G +
Sbjct:  244 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGA 330

HSP 2 Score: 69.707 bits (169), Expect = 1.003e-11
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  258 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 108.997 bits (271), Expect = 1.781e-24
Identity = 45/87 (51.72%), Postives = 59/87 (67.82%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +   E G +
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGA 368

HSP 2 Score: 70.0922 bits (170), Expect = 1.090e-11
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  296 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Match: EGR1 (early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238])

HSP 1 Score: 108.227 bits (269), Expect = 1.541e-23
Identity = 46/84 (54.76%), Postives = 58/84 (69.05%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D
Sbjct:  340 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKD 423

HSP 2 Score: 71.633 bits (174), Expect = 5.998e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  359 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 422
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 102.834 bits (255), Expect = 4.978e-22
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  347 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQ 423

HSP 2 Score: 67.0106 bits (162), Expect = 1.396e-10
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  361 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 424

HSP 3 Score: 59.3066 bits (142), Expect = 3.791e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  338 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 392
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 102.834 bits (255), Expect = 4.978e-22
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  347 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQ 423

HSP 2 Score: 67.0106 bits (162), Expect = 1.396e-10
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  361 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 424

HSP 3 Score: 59.3066 bits (142), Expect = 3.791e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  338 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 392
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Match: klu-1 (KLUmpfuss related [Source:UniProtKB/TrEMBL;Acc:O46016])

HSP 1 Score: 127.872 bits (320), Expect = 2.613e-30
Identity = 52/83 (62.65%), Postives = 65/83 (78.31%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            +C++C + F+RSDML RHMR+HTG KP+ C  C Q FSRSDHL+THLR H+GEKPY C +C+YSA RRDMI+RH+R H    D
Sbjct:  370 KCNMCSKSFSRSDMLTRHMRLHTGAKPYSCPTCNQVFSRSDHLSTHLRTHTGEKPYACPMCNYSASRRDMISRHMRTHSLTDD 452

HSP 2 Score: 63.5438 bits (153), Expect = 7.102e-10
Identity = 27/61 (44.26%), Postives = 37/61 (60.66%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHS 3369
            + L T A    C  C + F+RSD L+ H+R HTG KP+ C +C  S SR D ++ H+R HS
Sbjct:  388 MRLHTGAKPYSCPTCNQVFSRSDHLSTHLRTHTGEKPYACPMCNYSASRRDMISRHMRTHS 448
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 101.293 bits (251), Expect = 7.179e-25
Identity = 44/76 (57.89%), Postives = 55/76 (72.37%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            C + F+RSD L RH+R+HTG KPF+C IC + FSRSDHL TH+R H+GEKPY C IC     R D  TRH ++HK+
Sbjct:   20 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKK 95

HSP 2 Score: 64.3142 bits (155), Expect = 4.947e-12
Identity = 27/60 (45.00%), Postives = 36/60 (60.00%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            + + T     QC +C R F+RSD L  H+R HTG KP+ C ICG+ F+R D    H +IH
Sbjct:   34 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 93
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 106.686 bits (265), Expect = 7.717e-25
Identity = 45/78 (57.69%), Postives = 56/78 (71.79%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKG 3462
            C + F+RSD L RH+R+HTG KPF+C IC + FSRSDHL TH+R H+GEKPY C IC     R D  TRH ++HK+ G
Sbjct:  185 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSG 262

HSP 2 Score: 67.0106 bits (162), Expect = 1.709e-11
Identity = 28/65 (43.08%), Postives = 37/65 (56.92%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKP 3381
            + + T     QC +C R F+RSD L  H+R HTG KP+ C ICG+ F+R D    H +IH    P
Sbjct:  199 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 263
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 101.293 bits (251), Expect = 7.877e-25
Identity = 45/78 (57.69%), Postives = 56/78 (71.79%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKG 3462
            C + F+RSD L RH+R+HTG KPF+C IC + FSRSDHL TH+R H+GEKPY C IC     R D  TRH ++HK+ G
Sbjct:   20 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSG 97

HSP 2 Score: 65.0846 bits (157), Expect = 4.333e-12
Identity = 28/65 (43.08%), Postives = 37/65 (56.92%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKP 3381
            + + T     QC +C R F+RSD L  H+R HTG KP+ C ICG+ F+R D    H +IH    P
Sbjct:   34 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 98
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 105.531 bits (262), Expect = 1.360e-24
Identity = 47/100 (47.00%), Postives = 63/100 (63.00%), Query Frame = 1 
Query: 3157 LNCLSNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            + C     + ++LQ    +     C + F+RSD L RH+R+HTG KPF+C IC + FSRSDHL TH+R H+GEKPY C IC     R D  TRH ++HK+
Sbjct:  161 IGCQKMKSSKMHLQDRPYKCPRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKK 260
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Match: klu (gene:FBgn0013469 transcript:FBtr0076247)

HSP 1 Score: 134.035 bits (336), Expect = 2.246e-31
Identity = 56/84 (66.67%), Postives = 64/84 (76.19%), Query Frame = 1 
Query: 3205 ANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            A    C VC R F RSDML RHMR+HTG KP+ C +CGQ FSRSDHL+TH R H+GEKPY+C  C Y+ACRRDMITRH+R H R
Sbjct:  623 AKAYSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYAACRRDMITRHMRTHTR 706
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Match: klu (gene:FBgn0013469 transcript:FBtr0333361)

HSP 1 Score: 134.035 bits (336), Expect = 2.246e-31
Identity = 56/84 (66.67%), Postives = 64/84 (76.19%), Query Frame = 1 
Query: 3205 ANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            A    C VC R F RSDML RHMR+HTG KP+ C +CGQ FSRSDHL+TH R H+GEKPY+C  C Y+ACRRDMITRH+R H R
Sbjct:  623 AKAYSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYAACRRDMITRHMRTHTR 706
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Match: klu (gene:FBgn0013469 transcript:FBtr0345346)

HSP 1 Score: 134.035 bits (336), Expect = 2.246e-31
Identity = 56/84 (66.67%), Postives = 64/84 (76.19%), Query Frame = 1 
Query: 3205 ANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            A    C VC R F RSDML RHMR+HTG KP+ C +CGQ FSRSDHL+TH R H+GEKPY+C  C Y+ACRRDMITRH+R H R
Sbjct:  623 AKAYSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYAACRRDMITRHMRTHTR 706
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Match: klu (gene:FBgn0013469 transcript:FBtr0330080)

HSP 1 Score: 133.65 bits (335), Expect = 2.977e-31
Identity = 56/84 (66.67%), Postives = 64/84 (76.19%), Query Frame = 1 
Query: 3205 ANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            A    C VC R F RSDML RHMR+HTG KP+ C +CGQ FSRSDHL+TH R H+GEKPY+C  C Y+ACRRDMITRH+R H R
Sbjct:  623 AKAYSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYAACRRDMITRHMRTHTR 706
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0330050)

HSP 1 Score: 107.457 bits (267), Expect = 6.287e-23
Identity = 46/82 (56.10%), Postives = 57/82 (69.51%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C V  C R F+RSD L RH+R+HTG KPF+C IC +SFSRSDHL TH+R H+GEKP+ C IC     R D   RH +VH ++
Sbjct: 1038 CPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQ 1119

HSP 2 Score: 69.3218 bits (168), Expect = 2.214e-11
Identity = 28/60 (46.67%), Postives = 37/60 (61.67%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            + + T     QC +C R F+RSD L  H+R HTG KPF C ICG+ F+RSD    H ++H
Sbjct: 1057 IRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVH 1116
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:30498])

HSP 1 Score: 112.849 bits (281), Expect = 2.766e-25
Identity = 49/96 (51.04%), Postives = 62/96 (64.58%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVN 3501
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   E G +  V 
Sbjct:  313 CPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQ 408

HSP 2 Score: 72.4034 bits (176), Expect = 2.247e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  332 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQK 395
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:30498])

HSP 1 Score: 112.849 bits (281), Expect = 2.766e-25
Identity = 49/96 (51.04%), Postives = 62/96 (64.58%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVN 3501
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   E G +  V 
Sbjct:  313 CPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQ 408

HSP 2 Score: 72.4034 bits (176), Expect = 2.247e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  332 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQK 395
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 104.76 bits (260), Expect = 2.507e-24
Identity = 46/85 (54.12%), Postives = 57/85 (67.06%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETG 3483
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H+R  D     G
Sbjct:  155 CDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRKLSVG 239

HSP 2 Score: 66.6254 bits (161), Expect = 2.094e-11
Identity = 31/75 (41.33%), Postives = 43/75 (57.33%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSA 3411
            + + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH   K  + S+  +S+
Sbjct:  169 VRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRKLSVGPHSS 243

HSP 3 Score: 59.3066 bits (142), Expect = 6.875e-9
Identity = 27/55 (49.09%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  S  R D +T H+R H
Sbjct:  146 RPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTH 200
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 104.76 bits (260), Expect = 2.507e-24
Identity = 46/85 (54.12%), Postives = 57/85 (67.06%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETG 3483
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H+R  D     G
Sbjct:  155 CDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRKLSVG 239

HSP 2 Score: 66.6254 bits (161), Expect = 2.094e-11
Identity = 31/75 (41.33%), Postives = 43/75 (57.33%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSA 3411
            + + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH   K  + S+  +S+
Sbjct:  169 VRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRKLSVGPHSS 243

HSP 3 Score: 59.3066 bits (142), Expect = 6.875e-9
Identity = 27/55 (49.09%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  S  R D +T H+R H
Sbjct:  146 RPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTH 200
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Match: egr3 (early growth response 3 [Source:ZFIN;Acc:ZDB-GENE-040718-394])

HSP 1 Score: 107.071 bits (266), Expect = 7.190e-24
Identity = 49/88 (55.68%), Postives = 61/88 (69.32%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH-KRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH +VH K+K    T+ G+S
Sbjct:  304 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKDKKPTDKGSS 391

HSP 2 Score: 68.1662 bits (165), Expect = 3.337e-11
Identity = 29/64 (45.31%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H ++H  +K
Sbjct:  318 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 381
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 110.538 bits (275), Expect = 1.616e-24
Identity = 48/95 (50.53%), Postives = 62/95 (65.26%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVV 3498
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   +  T + V
Sbjct:  282 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKATPVSV 376

HSP 2 Score: 72.4034 bits (176), Expect = 2.389e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  301 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 364
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 110.153 bits (274), Expect = 2.400e-24
Identity = 48/95 (50.53%), Postives = 62/95 (65.26%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVV 3498
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   +  T + V
Sbjct:  309 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKATPVSV 403

HSP 2 Score: 72.4034 bits (176), Expect = 3.083e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  328 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 391
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Match: serpinb4 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:Xenbase;Acc:XB-GENE-5787878])

HSP 1 Score: 103.99 bits (258), Expect = 5.560e-23
Identity = 43/74 (58.11%), Postives = 53/74 (71.62%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H
Sbjct:  279 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIH 352

HSP 2 Score: 67.781 bits (164), Expect = 5.091e-11
Identity = 29/60 (48.33%), Postives = 36/60 (60.00%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH
Sbjct:  293 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIH 352
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Match: tbl1x (transducin beta like 1 X-linked [Source:Xenbase;Acc:XB-GENE-982285])

HSP 1 Score: 102.834 bits (255), Expect = 1.786e-22
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  268 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQ 344

HSP 2 Score: 67.3958 bits (163), Expect = 7.236e-11
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  282 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 345

HSP 3 Score: 59.3066 bits (142), Expect = 2.433e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  259 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 313
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Match: usp31 (ubiquitin specific peptidase 31 [Source:Xenbase;Acc:XB-GENE-920956])

HSP 1 Score: 101.293 bits (251), Expect = 2.751e-21
Identity = 45/82 (54.88%), Postives = 57/82 (69.51%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C V  C R F RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C +C     R D   RH +VH ++
Sbjct:  442 CPVESCIRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVHMKQ 523

HSP 2 Score: 67.781 bits (164), Expect = 8.280e-11
Identity = 29/64 (45.31%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R+F+RSD L  H+R HTG KPF C +CG+ F+RSD    H ++H  +K
Sbjct:  461 LRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVHMKQK 524
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 109.383 bits (272), Expect = 9.262e-25
Identity = 45/87 (51.72%), Postives = 60/87 (68.97%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +  +E G +
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGGA 368

HSP 2 Score: 70.0922 bits (170), Expect = 7.287e-12
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  296 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 108.612 bits (270), Expect = 1.006e-24
Identity = 45/87 (51.72%), Postives = 60/87 (68.97%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +  +E G +
Sbjct:  244 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGGA 330

HSP 2 Score: 69.707 bits (169), Expect = 7.075e-12
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  258 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Match: Egr1 (early growth response 1 [Source:MGI Symbol;Acc:MGI:95295])

HSP 1 Score: 108.227 bits (269), Expect = 9.416e-24
Identity = 46/84 (54.76%), Postives = 58/84 (69.05%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D
Sbjct:  338 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKD 421

HSP 2 Score: 71.633 bits (174), Expect = 4.130e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  357 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 420
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Match: Egr1 (early growth response 1 [Source:MGI Symbol;Acc:MGI:95295])

HSP 1 Score: 108.227 bits (269), Expect = 9.416e-24
Identity = 46/84 (54.76%), Postives = 58/84 (69.05%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D
Sbjct:  338 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKD 421

HSP 2 Score: 71.633 bits (174), Expect = 4.130e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  357 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 420
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Match: Egr2 (early growth response 2 [Source:MGI Symbol;Acc:MGI:95296])

HSP 1 Score: 102.064 bits (253), Expect = 3.295e-22
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  286 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQ 362

HSP 2 Score: 67.0106 bits (162), Expect = 8.901e-11
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  300 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQK 363

HSP 3 Score: 58.9214 bits (141), Expect = 3.119e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  277 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 331
[Close]
BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Match: sp|O73692|EGR1_COTJA (Early growth response protein 1 (Fragment) OS=Coturnix japonica OX=93934 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 9.856e-25
Identity = 46/88 (52.27%), Postives = 59/88 (67.05%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSL 3492
            C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   E   S+
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEKAASV 88

HSP 2 Score: 70.0922 bits (170), Expect = 3.799e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:   15 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78
[Close]
BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Match: sp|P26632|EGR1_DANRE (Early growth response protein 1 OS=Danio rerio OX=7955 GN=egr1 PE=2 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 2.088e-24
Identity = 49/96 (51.04%), Postives = 62/96 (64.58%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVN 3501
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   E G +  V 
Sbjct:  313 CPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQ 408

HSP 2 Score: 72.4034 bits (176), Expect = 1.696e-11
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  332 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQK 395
[Close]
BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Match: sp|O73693|EGR1_TAEGU (Early growth response protein 1 (Fragment) OS=Taeniopygia guttata OX=59729 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 2.932e-24
Identity = 44/79 (55.70%), Postives = 56/79 (70.89%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKD 79

HSP 2 Score: 70.4774 bits (171), Expect = 3.255e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:   15 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78
[Close]
BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Match: sp|P43300|EGR3_MOUSE (Early growth response protein 3 OS=Mus musculus OX=10090 GN=Egr3 PE=2 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 6.478e-24
Identity = 45/87 (51.72%), Postives = 60/87 (68.97%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +  +E G +
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGGA 368

HSP 2 Score: 70.0922 bits (170), Expect = 5.097e-11
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  296 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359
[Close]
BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Match: sp|P43301|EGR3_RAT (Early growth response protein 3 OS=Rattus norvegicus OX=10116 GN=Egr3 PE=2 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 7.654e-24
Identity = 45/87 (51.72%), Postives = 60/87 (68.97%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTS 3489
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H ++ +  +E G +
Sbjct:  282 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGGA 368

HSP 2 Score: 70.0922 bits (170), Expect = 5.571e-11
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  296 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A5K4F052 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 273.092 bits (697), Expect = 2.455e-71
Identity = 194/637 (30.46%), Postives = 304/637 (47.72%), Query Frame = 1 
Query:  235 QQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEEL-DSTNNDTTLK---FGCLC-SGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCK------------------------------RRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQD-----------------------KYCIDISLRSSVLPCGLIQMKYKNGNM-YSGLLQIWTDSKFPTPSRDMKFEINCKSQ-PNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQ 1965
            Q+ +NLAIG C Q    +C ++V NS C+ EKNECFC+ G V+++++G   CK LLT++KCR+D DC  V  S CHPGAG+C+CP  TI+VP++H C  R  +   +  C  C  +KGTCF+ EL +    D  +     GC+C   K ++ T+  D    +C+  L+DIG  C+D+ L CRS  +VCK                               R   I   C C    + VYQ +LKY EC   L  K   CQKC   GGQCY  +       CDC     S +      +S+  C +  V ++C    L VCY PH+  PY NL   L  +++ V L+SD+   D      +    E   +  + N   L +++S+  T D                       ++C++I +      CG+   K  +  + Y G+L++  ++   TPSRD    + C S+ PN+P N++     +T                 + PQI+L+ILN  + EI +  +G+ +++D LL + +  +  I  E CY +N S         +   +ID  C +   PL    FS   + +   HLQ+ +F AF++      V++ C+ ++C+ +T C++ T C+
Sbjct:   29 QKTENLAIGACTQYDSGFCSRQVENSVCNHEKNECFCRKGFVAIRENGRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRARFTYP-SDPFCDVCLQLKGTCFKYELFERVITDQRVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPLQEELLLSTNQLHSFKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKYCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSSIIYGKE--NSEIYCGTVHVSVNCTNGYLSVCYYPHTYGPYSNLFDDLMNHRSVVRLASDNYLTDTLPLQISGLSSEANRTYHYSNFQNLCILKSENDTIDIGNTFVTESISHDNYHLHGAQTKRFCLNIDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPLKCISRTPNRPMNEINDGNLQTIGTMNL-------ANTPTHPQISLRILNENNKEIPSTFVGSRVRLDALLFNPSGSYKHIAAEYCYGNNRSLHSDYFSSDTSTLLIDHRC-LHKKPLLTAKFSSIGLLNG--HLQTEIFQAFRLGNMTL-VFFTCVFRICQLSTDCEQ-TRCK 650
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A4Z2CXR8 (Endoglin antigen OS=Schistosoma japonicum OX=6182 GN=EWB00_006519 PE=4 SV=1)

HSP 1 Score: 272.707 bits (696), Expect = 3.060e-71
Identity = 199/648 (30.71%), Postives = 310/648 (47.84%), Query Frame = 1 
Query:  190 YVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEEL-DSTNNDTTLK---FGCLCSG-KNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCK------------------------------RRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXX----XXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQD--------------------KYCIDISLRSSVLPCGLIQMKY-KNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQ-PNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKK 1950
            Y I INV     LVY        G C+Q    +C ++V NS C+ EKNECFC+ G V+++++G   CK LLT++KCR+D DC  V  S CHPGAG+C+CP  TI+VP++H C  R  +   +  C  C  +KGTCF+ EL D    D  +     GC+C   + ++ T+  D    +C+  L+DIG  C+D+ L CRS  +VCK                               R   I   C+C    + VYQ +LKY EC   L  K   CQKC   GGQCY          CDC     S +      +S+  C ++ V ++C      VCY PHS  PY NL   L   ++ V L+S S   +     +L +  N+      S+   + C LKL    T  ++                    ++C+++ +      CG+   K  ++   Y G+L++  ++   TPS+D    + C S+ PN+P N++ ++L   E+M        S+ +  + PQI+L+ILN  + EI +  +G  I++D LL+D    +  I  E CY +N S      I  +   +ID  CS     L    FS+  + +   HLQ+ +F AF++     +V++ C+ ++C+ +  C++
Sbjct:   16 YFIIINVHTNDHLVYS-------GACSQYDLGFCSRQVENSVCNHEKNECFCRKGFVAIRENGRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRSRFIYP-NDPFCDVCLQLKGTCFKYELFDRVVTDQRVNPNGVGCVCPDHRVSINTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPVQEELLLSSTQLYSIPSSLWSENFPSGDPLRRNQIIRTCMCKPGYLPVYQINLKYNECFKILPMKAKRCQKCVDTGGQCYDLDDDGTGDGCDCPPSLSSIVYGKE--NSEIFCGTAHVSVNCTDGHFTVCYYPHSYGPYKNLFEDLVNYRSVVRLASGSYSTETIPRQTLVSLLNSVNATYRSANFQSSCMLKLENDTTDNENTFETDSFSFGNHHLHGKQSRRFCLNVDVWRQNGLCGIRLYKLGRDTVQYEGILEVLVNNSIRTPSKDKIIPLKCISRIPNRPMNKINENLQALETM--------SSSDTFTHPQISLRILNEKNKEILSAFVGLRIRLDALLIDPPGPYKYIAAEYCYGNNRSVHLNYSISETGTLLIDHRCSPRK-TLLSAKFSNNGLLNG--HLQTEIFQAFRL-GNMTSVFFTCVFRLCQLSKDCEQ 641
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A5K4F1C8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 263.462 bits (672), Expect = 3.293e-68
Identity = 190/633 (30.02%), Postives = 299/633 (47.24%), Query Frame = 1 
Query:  247 NLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEEL-DSTNNDTTLK---FGCLC-SGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCK------------------------------RRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQD-----------------------KYCIDISLRSSVLPCGLIQMKYKNGNM-YSGLLQIWTDSKFPTPSRDMKFEINCKSQ-PNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQ 1965
            NL+   C Q    +C ++V NS C+ EKNECFC+ G V+++++G   CK LLT++KCR+D DC  V  S CHPGAG+C+CP  TI+VP++H C  R  +   +  C  C  +KGTCF+ EL +    D  +     GC+C   K ++ T+  D    +C+  L+DIG  C+D+ L CRS  +VCK                               R   I   C C    + VYQ +LKY EC   L  K   CQKC   GGQCY  +       CDC     S +      +S+  C +  V ++C    L VCY PH+  PY NL   L  +++ V L+SD+   D      +    E   +  + N   L +++S+  T D                       ++C++I +      CG+   K  +  + Y G+L++  ++   TPSRD    + C S+ PN+P N++     +T                 + PQI+L+ILN  + EI +  +G+ +++D LL + +  +  I  E CY +N S         +   +ID  C +   PL    FS   + +   HLQ+ +F AF++      V++ C+ ++C+ +T C++ T C+
Sbjct:   45 NLSKRACTQYDSGFCSRQVENSVCNHEKNECFCRKGFVAIRENGRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRARFTYP-SDPFCDVCLQLKGTCFKYELFERVITDQRVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSVCKPLQEELLLSTNQLHSFKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKYCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSSIIYGKE--NSEIYCGTVHVSVNCTNGYLSVCYYPHTYGPYSNLFDDLMNHRSVVRLASDNYLTDTLPLQISGLSSEANRTYHYSNFQNLCILKSENDTIDIGNTFVTESISHDNYHLHGAQTKRFCLNIDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPLKCISRTPNRPMNEINDGNLQTIGTMNL-------ANTPTHPQISLRILNENNKEIPSTFVGSRVRLDALLFNPSGSYKHIAAEYCYGNNRSLHSDYFSSDTSTLLIDHRC-LHKKPLLTAKFSSIGLLNG--HLQTEIFQAFRLGNMTL-VFFTCVFRICQLSTDCEQ-TRCK 662
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A4E0RS07 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000222 PE=4 SV=1)

HSP 1 Score: 257.299 bits (656), Expect = 3.911e-66
Identity = 177/634 (27.92%), Postives = 271/634 (42.74%), Query Frame = 1 
Query:  232 YQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEELDSTNNDTTL----------------------------KFGCLCSGKNAMP------------------TKFIDDFSNV--------CEALLMDIGDFCNDQYLICRSPKAVC-------KRRTGSIENV--CLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCY-VNSVTSRKLQCDCGRLRISQLRDLRITDSD--------------DVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNA--YQENGESSFHHNMCQLKLMRSQTSTQDKYCIDISLRS--SVLPCGLIQMKYKNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPS-------TPVHLQSSLFP 1866
            Y + +NL IG C  +GDS+C +RV NS CS EKNECFCK G+VS+Q+  G  CK LLTN+KC++D DC  +  S CHPGAG C CP GTI+V Q H C +   +   N  C  C+ + G C++ +  S  + T L                             +GCLC    AMP                   +  D+   +        C+A+ +++G++CN+  ++CR+  + C        RR  S   V  C C+   + VYQ HL YYEC  +++     C  C   GG+C+ +N        C C   R   +    I   D              D C+ SL  +SC    L+VCY P + PPY  L + L   +A  F       +      F++        +  F  +      +         +C+ +  R+     PC +   +Y +G++YSG L I TD+++ +P R M F+  CK+    P    GQ  +R       D   S      S   I L+++N     I T    T I++   L D++ +++ + +E+CY S  S    D     E  ++ +GC     P           PS       +P   ++ +FP
Sbjct:   52 YLRLRNLDIGPCLHEGDSFCTRRVANSMCSTEKNECFCKPGYVSIQESYGITCKTLLTNLKCQVDADCVHIFNSACHPGAGLCACPSGTIYVAQDHACQQMAEYE-SNIFCNKCRQVNGMCYKRDKTSAESPTILHSQTNSDDTYHAAWYQTHRSIRSLLLGYPYGCLCPYNTAMPLATPRRTWITNETHKKLPVRQADELDRLEDLPQWSFCKAIFVNVGEYCNNIDVLCRAKFSHCIQNEDGSNRRGQSSPFVFTCTCAPGYVPVYQNHLGYYECFQQIAANHTDCSACIKTGGRCFSMNLQNPTATGCLCPHDRAPGIASKPIGSDDSHGIPNFASSDVGSDSCTESLAEVSCFRSHLEVCYRPPTQPPYNRLSNDLASQKAFAF-----VTDARPNLVFDDTCVLTPTTKHPFSLSAGLSPKLNESMKEDSLWCLVLDWRNDPGRQPCAVKVTEYMSGHLYSGYLAIVTDAEYQSPMRSMLFQFTCKTNNEIPQRVPGQVFERAWISENHDIDNS-----WSKVDIALELVNQTGQSIETAFEYTPIRLRAQLHDQSGKYHALHMEACYASQASVEDQDMGASHEYPVVIKGCPTRLLPGRSAPSRQETRPSPLAGLLESPAAFETDIFP 674
[Close]
BLAST of Endoglin CD105 antigen vs. TrEMBL
Match: A0A183MJ20 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS16045 PE=4 SV=1)

HSP 1 Score: 255.373 bits (651), Expect = 1.321e-65
Identity = 211/726 (29.06%), Postives = 328/726 (45.18%), Query Frame = 1 
Query:  181 VSFYVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEEL-DSTNNDTTLK---FGCLC-SGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCK------------------------------RRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSS-------------SLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQD-----------------------KYCIDISLRSSVLPCGLIQMKYKNGNM-YSGLLQIWTDSKFPTPSRDMKFEINCKSQ-PNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQF-------IIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVRI----NQRKENYNH 2106
            V  +++  NV     LVY        G C+Q   ++C ++V NS C+ EKNECFC+ G V+++++G   CK LLT++KCR+D DC  V  S CHPGAG+C+CP  TI+VP++H C  R  +   +  C  C  +KGTCF+ EL +    +  +     GC+C   K ++ T+  D    +C+  L+DIG  C+D+ L CRS  ++CK                               R   I   C C    + VYQ +LKY EC   L  K   CQKC   GGQCY  +       CDC     S +      +S+  C +              LV ++C    L VCY PH+  PY +L   L   ++   L+SD+   D      +    E   +  + N   L  ++S+  T D                       ++C+++ +      CG+   K  +  + Y G+L++  ++   TPSRD    I C S+ PN+P N++     +T   FG    +++       PQI+L+ILN  + EI +  +G+ I++D LL      +  I  E CY +N S        HS+ F       +ID  C +   PL    FS   + +   HLQ+ LF AF++      V++ C+ ++      C+ PT+C++   +     N+G     ++ I L   +  DNI P +     N  K NY H
Sbjct:   13 VYLFILYNNVYTNDHLVYS-------GACSQYDSNFCSRQVENSVCNYEKNECFCRKGFVAIRENGRVTCKTLLTDLKCRVDRDCVHVNRSSCHPGAGYCSCPGNTIYVPEKHACRSRFTYP-SDPFCDVCLQLKGTCFKYELFERVTTEERVNPNGVGCVCPDHKVSISTRTSDPLKYMCDGNLVDIGSECDDESLFCRSINSICKPLQEELLLSNNQLHSIKSNLWSENFPSGDHLRRSQIIRTCQCKPGYLPVYQINLKYNECFKILPMKAKHCQKCVDTGGQCYDLNDDGIGDGCDCPPSLSSIVYGKE--NSEIYCGTVHGTCNYDYFNFHVLVSVNCTNGYLSVCYYPHTYGPYSSLFDDLINYRSVARLASDNYMIDTLPLQISGLSSETNRTYHYSNFQNLCTLKSENDTTDTANTFVTESISHDNFHLHGSQTKRFCLNVDVWRKNGLCGIRLYKLSHDTVQYEGILEVLVNTSIRTPSRDKIIPIKCISRIPNRPMNKISVGNPQT---FGTMNLVNTPAH----PQISLRILNERNKEILSAFVGSHIRLDALL----RSYKHIAAEYCYGNNRSL-------HSDYFSSDIGTLLIDHRC-LHKKPLLTAKFSSIGLLNG--HLQTELFQAFRLGNMTL-VFFTCVFRI------CQLPTDCEQTKCKT----NDG-----IQKIHLTEINEKDNIIPFQSQIINNNSKNNYLH 691
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Match: EGR2 (early growth response protein 2b-like [Source:NCBI gene;Acc:103032442])

HSP 1 Score: 108.997 bits (271), Expect = 1.068e-24
Identity = 45/79 (56.96%), Postives = 58/79 (73.42%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C R F+RSD LARH+RVHTGHKPF+C IC +SF RSDHL TH+R H+GEKP+ C +C     R D   RH ++H+R+ +
Sbjct:  284 CDRRFSRSDELARHVRVHTGHKPFQCRICMRSFGRSDHLTTHIRTHTGEKPFACDLCGRKFARSDERRRHAKIHQRQSE 362

HSP 2 Score: 67.781 bits (164), Expect = 2.744e-11
Identity = 28/60 (46.67%), Postives = 36/60 (60.00%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            + + T     QC +C R F RSD L  H+R HTG KPF C +CG+ F+RSD    H +IH
Sbjct:  298 VRVHTGHKPFQCRICMRSFGRSDHLTTHIRTHTGEKPFACDLCGRKFARSDERRRHAKIH 357

HSP 3 Score: 59.3066 bits (142), Expect = 1.369e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+R+H+G KP+QC IC  S  R D +T H+R H
Sbjct:  275 RPYPCPAEGCDRRFSRSDELARHVRVHTGHKPFQCRICMRSFGRSDHLTTHIRTH 329
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:103035480])

HSP 1 Score: 107.457 bits (267), Expect = 5.654e-24
Identity = 45/79 (56.96%), Postives = 56/79 (70.89%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH +VH ++ D
Sbjct:  309 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKD 387

HSP 2 Score: 68.5514 bits (166), Expect = 1.863e-11
Identity = 29/64 (45.31%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H ++H  +K
Sbjct:  323 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 386
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:103046494])

HSP 1 Score: 103.99 bits (258), Expect = 5.653e-23
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  303 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQ 379

HSP 2 Score: 68.1662 bits (165), Expect = 2.272e-11
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  317 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQK 380

HSP 3 Score: 59.6918 bits (143), Expect = 1.399e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  294 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 348
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:103036296])

HSP 1 Score: 104.76 bits (260), Expect = 9.867e-23
Identity = 43/78 (55.13%), Postives = 55/78 (70.51%), Query Frame = 1 
Query: 3226 VCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
             C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+
Sbjct:  324 TCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQ 401

HSP 2 Score: 70.8626 bits (172), Expect = 5.274e-12
Identity = 29/60 (48.33%), Postives = 38/60 (63.33%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH
Sbjct:  339 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIH 398
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 100.523 bits (249), Expect = 2.859e-22
Identity = 42/77 (54.55%), Postives = 54/77 (70.13%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+RVHTGH+PF+C +C + F RSDHL TH+R H+GEKP+ C +C     R D   RH RVH ++
Sbjct:  244 CERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQ 320

HSP 2 Score: 70.8626 bits (172), Expect = 2.477e-12
Identity = 29/50 (58.00%), Postives = 33/50 (66.00%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            QC VC R F RSD L  HMR HTG KPF C +CG+ F+RSD    H R+H
Sbjct:  268 QCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVH 317
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 100.908 bits (250), Expect = 1.379e-23
Identity = 44/79 (55.70%), Postives = 54/79 (68.35%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C R F+R+D L RH+R+HTGHKPF C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH R+H +  D
Sbjct:  179 CDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIHLKGRD 257

HSP 2 Score: 64.3142 bits (155), Expect = 3.538e-11
Identity = 28/60 (46.67%), Postives = 35/60 (58.33%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            + + T      C +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H RIH
Sbjct:  193 IRIHTGHKPFTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIH 252
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009831.1 (pep scaffold:Pmarinus_7.0:GL485667:2222:3316:-1 gene:ENSPMAG00000008891.1 transcript:ENSPMAT00000009831.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.8113 bits (216), Expect = 8.807e-20
Identity = 42/124 (33.87%), Postives = 69/124 (55.65%), Query Frame = 1 
Query: 3166 LSNSKNVLNLQTTAN----QRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK--------GDIVTETGTSLVVN 3501
             + S ++   Q TA+      +C VCG+ F R + L  H RVH G KP+ C++CG  F+R++HL +H R H+GEKP++C+ C  +      ++ H R+H R+        G    E+  +L+V+
Sbjct:   67 FARSADLRAHQETAHGDGEAHKCDVCGKAFARPEALLSHQRVHMGEKPYRCSVCGMDFTRAEHLRSHHRTHTGEKPFRCATCGKAFAHPGTLSIHQRIHTRERPYECGACGKAFAESSGALLVH 190

HSP 2 Score: 74.3294 bits (181), Expect = 3.185e-15
Identity = 36/82 (43.90%), Postives = 49/82 (59.76%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYS-ACRRDMITRHLRVHKRK 3459
            +CSVCG  F R++ L  H R HTG KPF C  CG++F+    L+ H RIH+ E+PY+C  C  + A     +  H RVH R+
Sbjct:  116 RCSVCGMDFTRAEHLRSHHRTHTGEKPFRCATCGKAFAHPGTLSIHQRIHTRERPYECGACGKAFAESSGALLVHQRVHARE 197

HSP 3 Score: 62.7734 bits (151), Expect = 3.089e-11
Identity = 30/79 (37.97%), Postives = 45/79 (56.96%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRS-DMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +C  CG  F RS D+ A     H   +  +C +CG++F+R + L +H R+H GEKPY+CS+C     R + +  H R H
Sbjct:   59 ECRACGEAFARSADLRAHQETAHGDGEAHKCDVCGKAFARPEALLSHQRVHMGEKPYRCSVCGMDFTRAEHLRSHHRTH 137
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006002.1 (pep scaffold:Pmarinus_7.0:GL479218:16696:34135:-1 gene:ENSPMAG00000005404.1 transcript:ENSPMAT00000006002.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.1965 bits (217), Expect = 1.599e-19
Identity = 39/81 (48.15%), Postives = 51/81 (62.96%), Query Frame = 1 
Query: 3208 NQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
             Q +C  CGR F RSD L  HMR+HTG KP+ C  CG++FS+S  L TH R+H+GEKPY+C +C     +     RH + H
Sbjct:    3 QQYECRQCGREFVRSDALKAHMRIHTGEKPYRCGACGRAFSQSSGLKTHQRVHTGEKPYRCGVCGRVFAQSSHCNRHRKAH 83

HSP 2 Score: 63.1586 bits (152), Expect = 5.085e-11
Identity = 26/62 (41.94%), Postives = 37/62 (59.68%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICS 3402
            +C VC R F       RH R HTG +P+ C  CG++FS+  ++  H R H GEKP+ C +C+
Sbjct:  146 RCDVCSRAFAEYSNYRRHTRTHTGQRPYRCEACGRAFSKRSNMKRHQRSHKGEKPFGCDVCA 207

HSP 3 Score: 62.3882 bits (150), Expect = 1.031e-10
Identity = 28/75 (37.33%), Postives = 42/75 (56.00%), Query Frame = 1 
Query: 3178 KNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICS 3402
            K  + + T     +C  CGR F++S  L  H RVHTG KP+ C +CG+ F++S H N H + H+    + C  C+
Sbjct:   21 KAHMRIHTGEKPYRCGACGRAFSQSSGLKTHQRVHTGEKPYRCGVCGRVFAQSSHCNRHRKAHTVSHMHSCRQCT 95

HSP 4 Score: 60.077 bits (144), Expect = 6.075e-10
Identity = 30/75 (40.00%), Postives = 39/75 (52.00%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCS 3393
            SN +      T     +C  CGR F++   + RH R H G KPF C +C Q F+R  +L  HL  H+GE P  CS
Sbjct:  158 SNYRRHTRTHTGQRPYRCEACGRAFSKRSNMKRHQRSHKGEKPFGCDVCAQGFTRLCNLKVHLLKHAGEFPQICS 232

HSP 5 Score: 56.6102 bits (135), Expect = 7.117e-9
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 1 
Query: 3286 GHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            G + +EC  CG+ F RSD L  H+RIH+GEKPY+C  C  +  +   +  H RVH
Sbjct:    1 GRQQYECRQCGREFVRSDALKAHMRIHTGEKPYRCGACGRAFSQSSGLKTHQRVH 55

HSP 6 Score: 51.2174 bits (121), Expect = 4.834e-7
Identity = 25/82 (30.49%), Postives = 43/82 (52.44%), Query Frame = 1 
Query: 3268 HMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK---GDIVTETGTSLVVNV 3504
            H R +   +PF C +C ++F+   +   H R H+G++PY+C  C  +  +R  + RH R HK +   G  V   G + + N+
Sbjct:  135 HFRANICERPFRCDVCSRAFAEYSNYRRHTRTHTGQRPYRCEACGRAFSKRSNMKRHQRSHKGEKPFGCDVCAQGFTRLCNL 216
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000923.1 (pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 gene:ENSPMAG00000000839.1 transcript:ENSPMAT00000000923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 1.190e-18
Identity = 36/82 (43.90%), Postives = 47/82 (57.32%), Query Frame = 1 
Query: 3220 CSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLR--VHKRK 3459
            C  CGR F R     RH RVHTG +P+ C  CG+ F +  HL  H R+H+GE+PY C+ C     +   +TRHLR   H R+
Sbjct:   24 CGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLRSAAHARR 105

HSP 2 Score: 58.5362 bits (140), Expect = 1.192e-10
Identity = 23/64 (35.94%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3259 LARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            L  ++R HTG +P+ C  CG+ F+R  +   H R+H+GE+PY C+ C     ++  +  H R+H
Sbjct:    9 LGSNIRNHTGERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLH 72

HSP 3 Score: 53.9138 bits (128), Expect = 4.760e-9
Identity = 23/64 (35.94%), Postives = 34/64 (53.12%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLR 3360
            +N +    + T      C+ CGR F +   LA H R+HTG +P+ C  CG+ F++   L  HLR
Sbjct:   35 ANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLR 98
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003937.1 (pep scaffold:Pmarinus_7.0:GL485487:1616:4240:1 gene:ENSPMAG00000003606.1 transcript:ENSPMAT00000003937.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.5741 bits (205), Expect = 2.669e-18
Identity = 39/98 (39.80%), Postives = 58/98 (59.18%), Query Frame = 1 
Query: 3166 LSNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            LSN K  L + +     +C  CG+ F +   L +H  VHTG KP++C +C + FS + +L THLR+HSGEKP+QC +C     +   +  H R+H R+
Sbjct:   27 LSNLKVHLRIHSGERPFKCQTCGKGFTQLAHLQKHHLVHTGEKPYQCQVCCRRFSSTSNLKTHLRLHSGEKPFQCKLCPAKFTQFIHLKLHRRLHARE 124

HSP 2 Score: 80.8777 bits (198), Expect = 2.192e-17
Identity = 34/80 (42.50%), Postives = 52/80 (65.00%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            +C++CG+ F +   L  H+R+H+G +PF+C  CG+ F++  HL  H  +H+GEKPYQC +C    CRR   T +L+ H R
Sbjct:   16 ECNICGKTFGQLSNLKVHLRIHSGERPFKCQTCGKGFTQLAHLQKHHLVHTGEKPYQCQVC----CRRFSSTSNLKTHLR 91

HSP 3 Score: 67.781 bits (164), Expect = 6.996e-13
Identity = 30/83 (36.14%), Postives = 49/83 (59.04%), Query Frame = 1 
Query: 3193 LQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHL 3441
            + T     QC VC R F+ +  L  H+R+H+G KPF+C +C   F++  HL  H R+H+ E+P++C+ C  S   +  ++ HL
Sbjct:   64 VHTGEKPYQCQVCCRRFSSTSNLKTHLRLHSGEKPFQCKLCPAKFTQFIHLKLHRRLHARERPHRCADCQRSYIHQISLSLHL 146

HSP 4 Score: 52.7582 bits (125), Expect = 7.554e-8
Identity = 22/60 (36.67%), Postives = 35/60 (58.33%), Query Frame = 1 
Query: 3271 MRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            ++   G   +EC ICG++F +  +L  HLRIHSGE+P++C  C     +   + +H  VH
Sbjct:    6 LKKQNGKTIYECNICGKTFGQLSNLKVHLRIHSGERPFKCQTCGKGFTQLAHLQKHHLVH 65
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 84.7297 bits (208), Expect = 5.660e-17
Identity = 38/115 (33.04%), Postives = 61/115 (53.04%), Query Frame = 1 
Query: 3112 VVNSTHNLRKKSKGLLNCLSNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKR 3456
            + N T ++      L+  +   K   N +    + +C  C R F+++  L  H+R H G+KPF C  CG+ F++  +L TH R+H+GEKPY C IC     R+  +  HL  H++
Sbjct:  560 LFNQTMDILPPKSELVGGVEKPKGTQNTRAVK-KHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQK 673

HSP 2 Score: 64.6994 bits (156), Expect = 9.198e-11
Identity = 31/88 (35.23%), Postives = 45/88 (51.14%), Query Frame = 1 
Query: 3220 CSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSI--CSYSACRRDMITRHL-RVHKRKGDIVT 3474
            C  CG+ F +   L  H R+HTG KP+ C IC + FSR  +L  HL  H   KP+ C +  C+ +  +   +  H  R HK   + +T
Sbjct:  623 CDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALT 710
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 77.7962 bits (190), Expect = 7.238e-15
Identity = 32/91 (35.16%), Postives = 52/91 (57.14%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            L + +     +C  C R F+  + L +H R H+G KP++C IC + F+ S  L  H+R H+GEKP QC IC         +++H++ H++K
Sbjct:  759 LKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKK 849

HSP 2 Score: 67.781 bits (164), Expect = 9.697e-12
Identity = 34/97 (35.05%), Postives = 53/97 (54.64%), Query Frame = 1 
Query: 3166 LSNSKNVLNLQTTANQRQCSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            L++    ++L    ++ QC    C R F +   L RH++VH+ +KP++C  C + FS  + L  H R HSGEKPY+C IC+        +  H+R H
Sbjct:  722 LNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTH 818
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Match: MSN2 (Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004640])

HSP 1 Score: 72.7886 bits (177), Expect = 2.456e-13
Identity = 29/60 (48.33%), Postives = 41/60 (68.33%), Query Frame = 1 
Query: 3292 KPFECTICGQSFSRSDHLNTHLR-IHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDI 3468
            KPF C IC +SF RS+HL  H+R +HS E+P+ C IC     R D +++H++ HK+ GDI
Sbjct:  645 KPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHGDI 704
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Match: CRZ1 (Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972])

HSP 1 Score: 70.0922 bits (170), Expect = 1.512e-12
Identity = 34/105 (32.38%), Postives = 49/105 (46.67%), Query Frame = 1 
Query: 3181 NVLNLQTTANQRQ------CSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCS---------ICSYSACRRDMITRHLRVH 3450
            N+  L +  N R+      C VCG+ F R   L  H+R HT  +PF C+ICG++F+R      H  +H+G+K Y C           C     R D + RH +  
Sbjct:  552 NLEKLDSVTNNRKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTE 656

HSP 2 Score: 55.4546 bits (132), Expect = 5.391e-8
Identity = 22/54 (40.74%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 3298 FECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            F C +CG+ F+R  +L +HLR H+ E+P+ CSIC  +  R+    RH  +H  K
Sbjct:  569 FACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGK 622

HSP 3 Score: 52.373 bits (124), Expect = 4.816e-7
Identity = 30/88 (34.09%), Postives = 42/88 (47.73%), Query Frame = 1 
Query: 3193 LQTTANQRQ--CSVCGRHFNRSDMLARHMRVHTGHKPFEC---------TICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRD 3423
            L+T  N+R   CS+CG+ F R     RH  +HTG K + C           CG+ F+RSD L  H +  SG +   C    Y   R++
Sbjct:  588 LRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRR---CITPLYEEARQE 672
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Match: MSN4 (Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes, inducing gene expression; involved in diauxic shift [Source:SGD;Acc:S000001545])

HSP 1 Score: 67.3958 bits (163), Expect = 9.471e-12
Identity = 26/61 (42.62%), Postives = 40/61 (65.57%), Query Frame = 1 
Query: 3289 HKPFECTICGQSFSRSDHLNTHLR-IHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDI 3468
            +KPF+C  C ++F RS+HL  H+R +HS E+P+ C  C     R D +++HL+ HK+ GD 
Sbjct:  570 NKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTHKKHGDF 630

HSP 2 Score: 57.7658 bits (138), Expect = 9.741e-9
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMR-VHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            +C  C + F RS+ L RH+R VH+  +PF C  C + FSRSD+L+ HL+ H
Sbjct:  574 KCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH 624
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Match: EDO49112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGT8])

HSP 1 Score: 96.6709 bits (239), Expect = 5.811e-24
Identity = 43/78 (55.13%), Postives = 54/78 (69.23%), Query Frame = 1 
Query: 3226 VCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
             C R F+RSD L RHMR HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH+++H R+
Sbjct:   10 TCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

HSP 2 Score: 65.0846 bits (157), Expect = 6.834e-13
Identity = 30/64 (46.88%), Postives = 42/64 (65.62%), Query Frame = 1 
Query: 3190 NLQTTANQR--QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGE 3375
            +++T   Q+  QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H++IH  E
Sbjct:   24 HMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

HSP 3 Score: 58.151 bits (139), Expect = 1.626e-10
Identity = 27/65 (41.54%), Postives = 39/65 (60.00%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTET 3480
            +P+ C +  C + FSRSD L  H+R H+G+KP+QC IC  +  R D +T H+R H  +     ET
Sbjct:    2 RPYACPVETCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACET 66
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Match: EDO29702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2W2])

HSP 1 Score: 88.5817 bits (218), Expect = 3.451e-19
Identity = 40/94 (42.55%), Postives = 58/94 (61.70%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +N K  L + +     +C  CG+ F +   L RH+++HTG KP+EC  CG+ F+RS+ L THLRIHSG+KPY+C +C         + RHL +H
Sbjct:   77 ANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIH 170

HSP 2 Score: 85.8853 bits (211), Expect = 2.387e-18
Identity = 40/108 (37.04%), Postives = 61/108 (56.48%), Query Frame = 1 
Query: 3178 KNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH-KRKGDIVTETGTSLVV 3498
            K  L + T     +C  CG+ F RS+ L  H+R+H+G KP++C +CG+ FS S +L  HL IHSG+KPY+C +C         + +HL +H  +K     E G   ++
Sbjct:  108 KRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCFIL 215

HSP 3 Score: 83.9593 bits (206), Expect = 1.207e-17
Identity = 38/91 (41.76%), Postives = 58/91 (63.74%), Query Frame = 1 
Query: 3178 KNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            K  L + +     +C  CG+ F +S  L RH+R+H+G KP++C  CG+ F++S +L THLRIHSG+KPY+C  C     +   + RHL++H
Sbjct:   24 KRHLMIHSGQKPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIH 114

HSP 4 Score: 79.7221 bits (195), Expect = 3.063e-16
Identity = 42/107 (39.25%), Postives = 58/107 (54.21%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH-KRKGDIVTETGTSLVVNV 3504
            +NL    N+  C  CG  F R   L RH+ +H+G KP+ C  CG+ F++S  LN HLRIHSG+KPY+C  C     +   +  HLR+H  +K     E G   +  V
Sbjct:    1 MNLSEKPNE--CGECGMGFTRHAYLKRHLMIHSGQKPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYV 105

HSP 5 Score: 77.7962 bits (190), Expect = 1.453e-15
Identity = 34/88 (38.64%), Postives = 53/88 (60.23%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            L + +     +C  CG+ FN+S  L  H+R+H+G KP++C  CG+ F +   L  HL+IH+G+KPY+C  C     R + +  HLR+H
Sbjct:   55 LRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIH 142

HSP 6 Score: 77.411 bits (189), Expect = 2.037e-15
Identity = 36/91 (39.56%), Postives = 56/91 (61.54%), Query Frame = 1 
Query: 3178 KNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            K  L + +     +C VCG+ F+ S  L RH+ +H+G KP++C +CG+ FS S +L  HL IHSG+KPY+C  C     +  ++ R+L+ H
Sbjct:  136 KTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECG----KCFILYRNLKTH 222

HSP 7 Score: 65.4698 bits (158), Expect = 2.201e-11
Identity = 33/86 (38.37%), Postives = 51/86 (59.30%), Query Frame = 1 
Query: 3163 CLSNSKNV---LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNT---HLRIHSGEKPYQCSICS 3402
            C S S+N+   L + +     +C VCG+ F+ S  L +H+ +H+G KP++C  CG+ F    +L T   HL IHSG+KP++C  C 
Sbjct:  156 CFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCFILYRNLKTHLIHLMIHSGQKPHKCDECG 241
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Match: EDO43181 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ74])

HSP 1 Score: 83.5741 bits (205), Expect = 8.843e-19
Identity = 34/78 (43.59%), Postives = 49/78 (62.82%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +C +CGR F +S  L  H RVHTG KP++C +C + FS S  +  H+R H+GEKP+QC IC+     +  + +H R H
Sbjct:   23 KCPICGRPFAQSSGLESHKRVHTGQKPYKCEVCERGFSHSSAVKNHMRTHTGEKPFQCPICNKKFADQSTVKKHERTH 100

HSP 2 Score: 75.485 bits (184), Expect = 5.976e-16
Identity = 30/72 (41.67%), Postives = 45/72 (62.50%), Query Frame = 1 
Query: 3235 RHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            + + R+  L  H RVHTG KPF+C ICG+ F++S  L +H R+H+G+KPY+C +C         +  H+R H
Sbjct:    1 KKYARAFTLKTHQRVHTGEKPFKCPICGRPFAQSSGLESHKRVHTGQKPYKCEVCERGFSHSSAVKNHMRTH 72

HSP 3 Score: 70.8626 bits (172), Expect = 2.408e-14
Identity = 33/95 (34.74%), Postives = 47/95 (49.47%), Query Frame = 1 
Query: 3193 LQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTE 3477
            + T     +C VC R F+ S  +  HMR HTG KPF+C IC + F+    +  H R H+G KP+ C  C     +   + +HLR      D + E
Sbjct:   43 VHTGQKPYKCEVCERGFSHSSAVKNHMRTHTGEKPFQCPICNKKFADQSTVKKHERTHTGIKPFTCPECGLKFTQIGNMNKHLRKKHEAKDALKE 137

HSP 4 Score: 51.6026 bits (122), Expect = 1.165e-7
Identity = 24/64 (37.50%), Postives = 33/64 (51.56%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLR 3360
            S  KN +   T     QC +C + F     + +H R HTG KPF C  CG  F++  ++N HLR
Sbjct:   63 SAVKNHMRTHTGEKPFQCPICNKKFADQSTVKKHERTHTGIKPFTCPECGLKFTQIGNMNKHLR 126
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Match: EDO33478 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS19])

HSP 1 Score: 83.5741 bits (205), Expect = 1.446e-18
Identity = 34/89 (38.20%), Postives = 53/89 (59.55%), Query Frame = 1 
Query: 3193 LQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            + T     +C++CG+ FNRS  L  H+R+H G+KPF+C ICG+ F +  +   H   H+GEKP++C IC  +  +   +T H+  H  K
Sbjct:   31 IHTKEKPHKCNICGKAFNRSSTLNTHIRIHAGYKPFQCDICGKGFHQKGNYKNHRLTHTGEKPFKCHICGKAFHQVYNLTFHMHTHNEK 119

HSP 2 Score: 83.1889 bits (204), Expect = 2.028e-18
Identity = 36/86 (41.86%), Postives = 52/86 (60.47%), Query Frame = 1 
Query: 3193 LQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            + T A   +C +CG+ F ++  L RH  +HT  KP +C ICG++F+RS  LNTH+RIH+G KP+QC IC     ++     H   H
Sbjct:    3 VHTGARPFKCKICGKGFRQASTLCRHKIIHTKEKPHKCNICGKAFNRSSTLNTHIRIHAGYKPFQCDICGKGFHQKGNYKNHRLTH 88

HSP 3 Score: 68.9366 bits (167), Expect = 1.775e-13
Identity = 34/93 (36.56%), Postives = 52/93 (55.91%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLR-VHKRKGDIVTETGTSL 3492
            QC +CG+ F++      H   HTG KPF+C ICG++F +  +L  H+  H+ +KP+ C  C    CR   + +H+R +H+ K    TE G  L
Sbjct:   67 QCDICGKGFHQKGNYKNHRLTHTGEKPFKCHICGKAFHQVYNLTFHMHTHNEKKPFTCLECGKGFCRNFDLKKHVRKLHENKTQ--TENGKIL 157

HSP 4 Score: 62.7734 bits (151), Expect = 2.641e-11
Identity = 26/60 (43.33%), Postives = 39/60 (65.00%), Query Frame = 1 
Query: 3271 MRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            M VHTG +PF+C ICG+ F ++  L  H  IH+ EKP++C+IC  +  R   +  H+R+H
Sbjct:    1 MPVHTGARPFKCKICGKGFRQASTLCRHKIIHTKEKPHKCNICGKAFNRSSTLNTHIRIH 60
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Match: EDO43177 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ64])

HSP 1 Score: 83.9593 bits (206), Expect = 1.491e-18
Identity = 36/97 (37.11%), Postives = 60/97 (61.86%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            +N K  L + +     +C +C R F +S  +  HMR+H+G +P++C +C + FS S  L   LR H+GEKPYQC IC  S  +   ++RH+R+++++
Sbjct:   75 ANLKAHLRVHSKEKPFKCHICHRRFAQSSSVTTHMRIHSGERPYKCKVCARGFSDSSTLTKRLRTHTGEKPYQCRICGMSFSQSGNLSRHMRIYRKR 171

HSP 2 Score: 79.337 bits (194), Expect = 7.570e-17
Identity = 35/77 (45.45%), Postives = 49/77 (63.64%), Query Frame = 1 
Query: 3220 CSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            C VC + ++R   L  H+RVHTG KPF C  C +SFS+  +L  HLR+HS EKP++C IC     +   +T H+R+H
Sbjct:   36 CHVCHKIYSRPSTLKAHLRVHTGKKPFRCPTCQKSFSQDANLKAHLRVHSKEKPFKCHICHRRFAQSSSVTTHMRIH 112

HSP 3 Score: 76.2554 bits (186), Expect = 6.914e-16
Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 1 
Query: 3169 SNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            S  K  L + T     +C  C + F++   L  H+RVH+  KPF+C IC + F++S  + TH+RIHSGE+PY+C +C+        +T+ LR H
Sbjct:   47 STLKAHLRVHTGKKPFRCPTCQKSFSQDANLKAHLRVHSKEKPFKCHICHRRFAQSSSVTTHMRIHSGERPYKCKVCARGFSDSSTLTKRLRTH 140

HSP 4 Score: 60.077 bits (144), Expect = 3.144e-10
Identity = 26/54 (48.15%), Postives = 37/54 (68.52%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            +C VC R F+ S  L + +R HTG KP++C ICG SFS+S +L+ H+RI+   K
Sbjct:  119 KCKVCARGFSDSSTLTKRLRTHTGEKPYQCRICGMSFSQSGNLSRHMRIYRKRK 172
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Match: ENSORLT00000000940.2 (early growth response protein 1 [Source:NCBI gene;Acc:101160576])

HSP 1 Score: 108.612 bits (270), Expect = 2.705e-24
Identity = 47/92 (51.09%), Postives = 61/92 (66.30%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVNV 3504
            C R F+RSD L RH+RVHTG KPF+C IC +SFSRSDHL TH+R H+GEKP+ CS C     R D   RH ++H+R+ D   +  T+ +   
Sbjct:  290 CERRFSRSDELTRHVRVHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIHQRQRDRKPDGATATIPEA 381

HSP 2 Score: 67.781 bits (164), Expect = 4.597e-11
Identity = 27/50 (54.00%), Postives = 34/50 (68.00%), Query Frame = 1 
Query: 3217 QCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIH 3366
            QC +C R F+RSD L  H+R HTG KPF C+ CG+ F+RSD    H +IH
Sbjct:  314 QCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIH 363
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:100272164])

HSP 1 Score: 107.071 bits (266), Expect = 5.182e-24
Identity = 45/79 (56.96%), Postives = 56/79 (70.89%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD 3465
            C R F+RSD L RH+R+HTGHKPF+C IC +SFSRSDHL TH+R H+GEKP+ C  C     R D   RH +VH ++ D
Sbjct:  303 CDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKD 381

HSP 2 Score: 68.5514 bits (166), Expect = 2.078e-11
Identity = 29/64 (45.31%), Postives = 38/64 (59.38%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R F+RSD L  H+R HTG KPF C  CG+ F+RSD    H ++H  +K
Sbjct:  317 LRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 380
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100272163])

HSP 1 Score: 107.457 bits (267), Expect = 1.371e-23
Identity = 47/88 (53.41%), Postives = 59/88 (67.05%), Query Frame = 1 
Query: 3220 CSV--CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTE 3477
            C V  C R F+RSD L RH+R+HTG KPF+C IC ++FSRSDHL TH+R H+GEKP+ C IC     R D   RH ++H R+ D   E
Sbjct:  315 CPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQKDKKAE 402

HSP 2 Score: 71.633 bits (174), Expect = 3.022e-12
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C ICG+ F+RSD    H +IH  +K
Sbjct:  334 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQK 397
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Match: ENSORLT00000034291.1 (early growth response protein 2b [Source:NCBI gene;Acc:101164744])

HSP 1 Score: 104.76 bits (260), Expect = 2.790e-23
Identity = 43/77 (55.84%), Postives = 57/77 (74.03%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L+RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH+++H R+
Sbjct:  311 CDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIHLRQ 387

HSP 2 Score: 68.9366 bits (167), Expect = 1.202e-11
Identity = 30/64 (46.88%), Postives = 40/64 (62.50%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            L + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H++IH  +K
Sbjct:  325 LRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIHLRQK 388

HSP 3 Score: 60.8474 bits (146), Expect = 5.801e-9
Identity = 27/55 (49.09%), Postives = 36/55 (65.45%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L+ HLRIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  302 RPYPCPAESCDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 356
[Close]
BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:101170128])

HSP 1 Score: 103.605 bits (257), Expect = 1.217e-22
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1 
Query: 3229 CGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRK 3459
            C R F+RSD L RH+R+HTGHKPF+C IC ++FSRSDHL TH+R H+GEKP+ C  C     R D   RH ++H R+
Sbjct:  337 CDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQ 413

HSP 2 Score: 67.781 bits (164), Expect = 4.177e-11
Identity = 29/64 (45.31%), Postives = 39/64 (60.94%), Query Frame = 1 
Query: 3187 LNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEK 3378
            + + T     QC +C R+F+RSD L  H+R HTG KPF C  CG+ F+RSD    H +IH  +K
Sbjct:  351 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQK 414

HSP 3 Score: 59.3066 bits (142), Expect = 1.828e-8
Identity = 26/55 (47.27%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 3292 KPFECTI--CGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVH 3450
            +P+ C    C + FSRSD L  H+RIH+G KP+QC IC  +  R D +T H+R H
Sbjct:  328 RPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTH 382
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000025327.1 (SMESG000025327.1)

HSP 1 Score: 1606.27 bits (4158), Expect = 0.000e+0
Identity = 804/804 (100.00%), Postives = 804/804 (100.00%), Query Frame = 1 
Query:  166 MQYLWVSFYVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEELDSTNNDTTLKFGCLCSGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCKRRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQDKYCIDISLRSSVLPCGLIQMKYKNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVRINQRKENYNHVCQYPMCLSLGHLSMIAASFSXXXXXXXXXXXXXYRKHFHHFRLFSQLSSDTNHKICTYNSNKNILNDEPLNNIDANDCYKEFMYINPRQIMSDNYYEDIVTGSTINPQWRLGISKPLVMNDMEVSYCLDNMYLDSTHSCLLDSYQEPISPETMSRF 2577
            MQYLWVSFYVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEELDSTNNDTTLKFGCLCSGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCKRRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFLSSDSSENDESLPNFNNAYQENGESSFHHNMCQLKLMRSQTSTQDKYCIDISLRSSVLPCGLIQMKYKNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVRINQRKENYNHVCQYPMCLSLGHLSMIAASFSIILILTILLLILLYRKHFHHFRLFSQLSSDTNHKICTYNSNKNILNDEPLNNIDANDCYKEFMYINPRQIMSDNYYEDIVTGSTINPQWRLGISKPLVMNDMEVSYCLDNMYLDSTHSCLLDSYQEPISPETMSRF
Sbjct:    1 MQYLWVSFYVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEELDSTNNDTTLKFGCLCSGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCKRRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFLSSDSSENDESLPNFNNAYQENGESSFHHNMCQLKLMRSQTSTQDKYCIDISLRSSVLPCGLIQMKYKNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVRINQRKENYNHVCQYPMCLSLGHLSMIAASFSIILILTILLLILLYRKHFHHFRLFSQLSSDTNHKICTYNSNKNILNDEPLNNIDANDCYKEFMYINPRQIMSDNYYEDIVTGSTINPQWRLGISKPLVMNDMEVSYCLDNMYLDSTHSCLLDSYQEPISPETMSRF 804
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BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000064481.1 (SMESG000064481.1)

HSP 1 Score: 337.035 bits (863), Expect = 2.373e-107
Identity = 185/185 (100.00%), Postives = 185/185 (100.00%), Query Frame = 1 
Query: 3256 MLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVNVXXXXXXXXXXXXXXXXXXXXXIARDELNDMKESISSLYRSRSFTDDGRCVDYEDIDNSLIISDSPIERPVLPPRTFANISISISQPTPRSSFSIPMETQNYG 3810
            MLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVNVNKQKTTQHKKKSKLKAQNSLNIARDELNDMKESISSLYRSRSFTDDGRCVDYEDIDNSLIISDSPIERPVLPPRTFANISISISQPTPRSSFSIPMETQNYG
Sbjct:    1 MLARHMRVHTGHKPFECTICGQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGDIVTETGTSLVVNVNKQKTTQHKKKSKLKAQNSLNIARDELNDMKESISSLYRSRSFTDDGRCVDYEDIDNSLIISDSPIERPVLPPRTFANISISISQPTPRSSFSIPMETQNYG 185
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000068315.1 (SMESG000068315.1)

HSP 1 Score: 299.286 bits (765), Expect = 8.523e-86
Identity = 218/705 (30.92%), Postives = 350/705 (49.65%), Query Frame = 1 
Query:  259 GECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNN--LCKACKNIKGTCFQEELDSTN---------NDTTLKFGCLCSGKNAMPTKFIDDFSN-VCEALLMDIGDFCNDQYLICRSPKAVCKRRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDD-------VCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNMCQLKLMRSQTSTQD--KYCIDISLRS--SVLPCGLIQMKYKNGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQ-ITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGC--SVSNF--PLFQNLFSDAKIPSTP-----VHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSI---NNEGDVKFVVRSIKLQVRSFDDNISPVRINQRKENYNHVCQYPMCLSLGHLSMIAASFSXXXXXXXXXXXXXYRKHFHHFRLFSQLSSDTN 2265
            G C + G+ +C ++V NSFC  +KN+C+CK   V++++  G  CKPLLTN+KC +D +C DV GS CHPGAG CTCP  T++VPQ H C K++  S +N+  LC  CK I G CFQ      N          +     GC C G   + +  +DD S+ +C  +L+DIG  CN+  LICRS KAVC   +    ++C C    +AVYQ +L Y+EC P +      C+ C    G C+  +   +   C CGRL+  Q  D +   + +        CS ++V I C  + L++CY P   P +      + K +A +F++             ++ ++E  + S  +N C L +  +  S  +  ++CI+  L +    LPCG+   KY NG +YSG + +W D  F  P  D   + +CK   +      GQ++DR+  +  ++ +++ N E  +T +     ILN  ++ + ++     IK+  +L     E+N I  ESC+ +N   S  D   +++  +I+RGC  S S F  P   +  S +   S P     V L S  FPAF +F   + + ++CL + C+H  WC     C +   + F+        D++F+V+S K+ V S     S  R   +      VC +  CL    L ++ +  ++IL+L   L  +L+R+H       S +  +TN
Sbjct:   30 GPCLEYGNRFCEEKVANSFCLKKKNKCYCKPQFVNIKESYGVTCKPLLTNLKCNMDKNCRDVDGSTCHPGAGACTCPYNTLYVPQLHACKKQI-LSPENDAILCIKCKEIGGECFQYTNQIGNIHSYPVSNAGNNFPHIGCSCPGITTIQSDKVDDLSDAICNQILVDIGHPCNNMDLICRSSKAVCFETSLFSYSICHCPPGHVAVYQEYLGYHECYPSIKLNVDSCRLCLRTNGLCFDMNADEQPDGCYCGRLKTVQ-EDFKANGAHNDQNSLLQTCSKNIVEIFCWPENLKICYYPPKAPNHARFIDNITKQRALIFITDG-----------HSLFRE--DDSGPNNECLLTIEETHRSRDNSIRFCIEKQLNTLEVNLPCGISATKYSNGYLYSGYVAVWVDKYFADPISDQLIDFSCKCDYSFLRMTPGQAIDRSWPV--ENINLNYNRESNTTTEFFNFSILNPDNSVVYSVFKMAPIKLYAVLNTEEIEYNSIAAESCWCTN---SSDDSSPNNKWKLINRGCIESRSGFTTPFLLSSNSASTNQSNPDRKAFVELSSGFFPAFTMFDSSQ-LIFKCLFRFCKHKHWCSLRKQCTDDHPQFFTTPPPKRFDDIRFLVKSFKVSVVSVPKVDSVSRGGVKS-----VCSFFWCLPGDKLLLVISLLTVILLLVTALAFVLFRRHNQLINYRSNVFKETN 708
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000064487.1 (SMESG000064487.1)

HSP 1 Score: 269.24 bits (687), Expect = 2.501e-78
Identity = 158/158 (100.00%), Postives = 158/158 (100.00%), Query Frame = 1 
Query: 2599 KDPGSMNINLIPXXXXXXXXXVNETENYYIKFQEKVTGQRFFPDXXXXXXXXXXXXXXXEAGDQQHIKKHLILPDLSNSRQNSQSAPNSIETISDLNKQPLSQSTASLECPAYSPSYPTNDVRRISNSRSMDHINSYVAKRNNDYISKSFDDDASKFT 3072
            KDPGSMNINLIPSSSLSALSSVNETENYYIKFQEKVTGQRFFPDSMKISDFSSVKSSKSEAGDQQHIKKHLILPDLSNSRQNSQSAPNSIETISDLNKQPLSQSTASLECPAYSPSYPTNDVRRISNSRSMDHINSYVAKRNNDYISKSFDDDASKFT
Sbjct:  359 KDPGSMNINLIPSSSLSALSSVNETENYYIKFQEKVTGQRFFPDSMKISDFSSVKSSKSEAGDQQHIKKHLILPDLSNSRQNSQSAPNSIETISDLNKQPLSQSTASLECPAYSPSYPTNDVRRISNSRSMDHINSYVAKRNNDYISKSFDDDASKFT 516
[Close]
BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Match: SMESG000039228.1 (SMESG000039228.1)

HSP 1 Score: 276.559 bits (706), Expect = 2.923e-78
Identity = 211/706 (29.89%), Postives = 346/706 (49.01%), Query Frame = 1 
Query:  211 QVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSFCSLEKNECFCKVGHVSVQDDGGTV-CKPLLTNVKCRLDTDCTDVKGSICHPGAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCF-----QEELDSTNNDTTLKFGCLCSGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICRSPKAVCKRRTGSIE-NVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKCYSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISCNYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFXXXXXXXXXXXXXXFNNAYQENGESSFHHNM-CQLKLMRSQTSTQDKYCIDISLRSSVLPCGLIQMKYKNGNM-YSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTESMFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDRNAEFNGIEVESCYVSNISFSKF-DPIKHSEQFIIDRGCSVSNFPLFQNLFSDAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQEKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVR--INQRKENYNHV--CQYPMCLSLGHLSMIAASFSXXXXXXXXXXXXXYRKHFHHFRLFSQLSSDTNHKICTYN 2286
            QV+  L YQ+ QNL IG C      +C ++V NS C+ EKNECFCK G V+++++   V CK LLT++KCR+D DC  V  S CHPGAG+C+CP  TI+  + H C  +      N  C  C+N  G CF      ++      D +   GC C  K   P   I     +C   L+DIGD+C+D   ICRS KA+C  ++ + +  +C+C +  I +YQ +L Y+EC P L+     C  C +  G CY  +       C C  +  +    +     +  C+ S +  +C    L+VCY PHS PPY  L+  L    A + L                     G S F  N  C L  +      ++++CI+I L   +  CG+   K  +  + Y  +L++ ++  F TPS+DM+F ++C ++  +P + +      T+S      SI    +  +   + L++L++ +NEI +++ G+ IK+D+ L+D   ++  I VE CY SN S   + D +      +I +GC         N F    +P   +H+QS  F AF++      ++  C +KVC +   C +  +C  KS ++ S   +    +V+   + Q+     NI   R   N +K+N      C Y +CL+    S++AA    ++IL I +++++YRK+    RL+ + +   +H +  +N
Sbjct:   30 QVESILEYQKTQNLNIGSCVGKPSDFCSKQVDNSICNDEKNECFCKRGFVAIREEEDKVSCKTLLTDLKCRMDRDCNHVNSSTCHPGAGYCSCPGHTIYSSELHACRVKTFQIENNQFCLVCRNEGGVCFFYKDYDKKTAYIRADNSY-VGCACPMKR-FPISDIK--HEICNNNLVDIGDYCDDNKDICRSKKAICAEKSMNNQIKICVCPKGYIKLYQSNLHYHECFPILNENSPLCSLCAASKGTCYDINDDDVGDGCICPSMYSTAETQIEFKHQNQFCTISHLESNCKNNILKVCYKPHSQPPYDYLKDDLINKNAIIRLI--------------------GGSDFKANSECFLNFVED----ENQFCINIDLLEQIRECGIRSYKIAHRKLQYEFILEVLSNKSFKTPSKDMQFPLSCITK--EPESAIKTYQTSTKSNQDIKNSIRKQKDKFN---LGLQVLDNNNNEIESVEEGSIIKLDLSLIDTKGKYKAISVEQCYFSNYSTIDYADSLSDKSVLLIKKGCPNVREGFMAN-FRSRIMPG--IHIQSDGFHAFKLTTDSNILFIDCFIKVCINEANCWQ-IDCN-KSPQQISQPKDDKSNYVIVRRRTQL-----NILKKRRFTNTKKQNKVTFGKCTYAVCLTALQTSVMAALLVTLIILIIFIILVIYRKN----RLYQEQNKMAHHCLNEHN 688
The following BLAST results are available for this feature:
BLAST of Endoglin CD105 antigen vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EGR31.669e-2451.72early growth response 3 [Source:HGNC Symbol;Acc:HG... [more]
EGR31.781e-2451.72early growth response 3 [Source:HGNC Symbol;Acc:HG... [more]
EGR11.541e-2354.76early growth response 1 [Source:HGNC Symbol;Acc:HG... [more]
EGR24.978e-2255.84early growth response 2 [Source:HGNC Symbol;Acc:HG... [more]
EGR24.978e-2255.84early growth response 2 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
klu-12.613e-3062.65KLUmpfuss related [Source:UniProtKB/TrEMBL;Acc:O4... [more]
egrh-27.179e-2557.89EGR (Early Growth factor Response factor) Homolog ... [more]
egrh-27.717e-2557.69EGR (Early Growth factor Response factor) Homolog ... [more]
egrh-27.877e-2557.69EGR (Early Growth factor Response factor) Homolog ... [more]
egrh-21.360e-2447.00EGR (Early Growth factor Response factor) Homolog ... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
klu2.246e-3166.67gene:FBgn0013469 transcript:FBtr0076247[more]
klu2.246e-3166.67gene:FBgn0013469 transcript:FBtr0333361[more]
klu2.246e-3166.67gene:FBgn0013469 transcript:FBtr0345346[more]
klu2.977e-3166.67gene:FBgn0013469 transcript:FBtr0330080[more]
sr6.287e-2356.10gene:FBgn0003499 transcript:FBtr0330050[more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egr12.766e-2551.04early growth response 1 [Source:NCBI gene;Acc:3049... [more]
egr12.766e-2551.04early growth response 1 [Source:NCBI gene;Acc:3049... [more]
egr2a2.507e-2454.12early growth response 2a [Source:ZFIN;Acc:ZDB-GENE... [more]
egr2a2.507e-2454.12early growth response 2a [Source:ZFIN;Acc:ZDB-GENE... [more]
egr37.190e-2455.68early growth response 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egr11.616e-2450.53early growth response 1 [Source:NCBI gene;Acc:1000... [more]
egr12.400e-2450.53early growth response 1 [Source:NCBI gene;Acc:1000... [more]
serpinb45.560e-2358.11serpin peptidase inhibitor, clade B (ovalbumin), m... [more]
tbl1x1.786e-2255.84transducin beta like 1 X-linked [Source:Xenbase;Ac... [more]
usp312.751e-2154.88ubiquitin specific peptidase 31 [Source:Xenbase;Ac... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Egr39.262e-2551.72early growth response 3 [Source:MGI Symbol;Acc:MGI... [more]
Egr31.006e-2451.72early growth response 3 [Source:MGI Symbol;Acc:MGI... [more]
Egr19.416e-2454.76early growth response 1 [Source:MGI Symbol;Acc:MGI... [more]
Egr19.416e-2454.76early growth response 1 [Source:MGI Symbol;Acc:MGI... [more]
Egr23.295e-2255.84early growth response 2 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Endoglin CD105 antigen vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O73692|EGR1_COTJA9.856e-2552.27Early growth response protein 1 (Fragment) OS=Cotu... [more]
sp|P26632|EGR1_DANRE2.088e-2451.04Early growth response protein 1 OS=Danio rerio OX=... [more]
sp|O73693|EGR1_TAEGU2.932e-2455.70Early growth response protein 1 (Fragment) OS=Taen... [more]
sp|P43300|EGR3_MOUSE6.478e-2451.72Early growth response protein 3 OS=Mus musculus OX... [more]
sp|P43301|EGR3_RAT7.654e-2451.72Early growth response protein 3 OS=Rattus norvegic... [more]
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BLAST of Endoglin CD105 antigen vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4F0522.455e-7130.46Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4Z2CXR83.060e-7130.71Endoglin antigen OS=Schistosoma japonicum OX=6182 ... [more]
A0A5K4F1C83.293e-6830.02Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4E0RS073.911e-6627.92Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
A0A183MJ201.321e-6529.06Uncharacterized protein OS=Schistosoma margrebowie... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EGR21.068e-2456.96early growth response protein 2b-like [Source:NCBI... [more]
egr35.654e-2456.96early growth response 3 [Source:NCBI gene;Acc:1030... [more]
egr2b5.653e-2355.84early growth response 2 [Source:NCBI gene;Acc:1030... [more]
egr19.867e-2355.13early growth response 1 [Source:NCBI gene;Acc:1030... [more]
egr42.859e-2254.55early growth response protein 1-B [Source:NCBI gen... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egr41.379e-2355.70early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-... [more]
ENSPMAT00000009831.18.807e-2033.87pep scaffold:Pmarinus_7.0:GL485667:2222:3316:-1 ge... [more]
ENSPMAT00000006002.11.599e-1948.15pep scaffold:Pmarinus_7.0:GL479218:16696:34135:-1 ... [more]
ENSPMAT00000000923.11.190e-1843.90pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 ... [more]
ENSPMAT00000003937.12.669e-1839.80pep scaffold:Pmarinus_7.0:GL485487:1616:4240:1 gen... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
AZF15.660e-1733.04Zinc-finger transcription factor; involved in diau... [more]
ZAP17.238e-1535.16Zinc-regulated transcription factor; binds to zinc... [more]
MSN22.456e-1348.33Stress-responsive transcriptional activator; activ... [more]
CRZ11.512e-1232.38Transcription factor, activates transcription of s... [more]
MSN49.471e-1242.62Stress-responsive transcriptional activator; activ... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO491125.811e-2455.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297023.451e-1942.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431818.843e-1943.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334781.446e-1838.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431771.491e-1837.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Endoglin CD105 antigen vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000000940.22.705e-2451.09early growth response protein 1 [Source:NCBI gene;... [more]
egr35.182e-2456.96early growth response 3 [Source:NCBI gene;Acc:1002... [more]
egr11.371e-2353.41early growth response 1 [Source:NCBI gene;Acc:1002... [more]
ENSORLT00000034291.12.790e-2355.84early growth response protein 2b [Source:NCBI gene... [more]
egr2b1.217e-2255.84early growth response 2 [Source:NCBI gene;Acc:1011... [more]
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BLAST of Endoglin CD105 antigen vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000025327.10.000e+0100.00SMESG000025327.1[more]
SMESG000064481.12.373e-107100.00SMESG000064481.1[more]
SMESG000068315.18.523e-8630.92SMESG000068315.1[more]
SMESG000064487.12.501e-78100.00SMESG000064487.1[more]
SMESG000039228.12.923e-7829.89SMESG000039228.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033385 ID=SMED30033385|Name=Endoglin CD105 antigen|organism=Schmidtea mediterranea sexual|type=transcript|length=4055bp
CTTCCGATCTTAGTATTCGTAGAACGAAATAGTATTGGTTCATCTGCCGA
TACTTAAAAACCTCAATTCTTCCAATGCCATATTGATATATATTATCGTT
GTTCAATCAATTTACTTTCTCGATTTTTTTTATTTTTTTTGTTTTAACCA
GCACGTTAGTAAAACATGCAATATTTATGGGTTTCGTTCTACGTGATTGC
GATTAATGTTCAGGTTCAAAAATCTTTGGTCTATCAACAGCCACAAAATC
TCGCTATTGGAGAATGTGCGCAAGACGGAGACTCGTATTGTTTACAAAGA
GTTCCGAATAGTTTCTGTTCGTTGGAGAAAAATGAATGCTTCTGTAAAGT
CGGACATGTTTCTGTGCAAGACGACGGCGGAACCGTATGCAAGCCATTAT
TAACAAATGTTAAGTGCCGCTTGGATACTGACTGCACTGACGTAAAAGGA
AGCATTTGTCATCCAGGAGCAGGATTTTGCACTTGTCCCGAAGGAACGAT
ATTTGTTCCACAAAGACATCAATGCATGAAAAGAGTACATTGGTCAGTTC
AAAATAATCTATGTAAAGCTTGTAAGAACATAAAAGGAACTTGTTTTCAA
GAGGAACTAGATTCAACCAACAACGATACAACATTAAAATTCGGATGCCT
CTGTTCCGGAAAGAATGCTATGCCAACCAAATTCATAGATGATTTTTCCA
ATGTCTGTGAAGCATTACTCATGGATATCGGAGATTTCTGCAATGACCAA
TATTTGATTTGCCGTTCTCCAAAGGCGGTTTGCAAGCGAAGAACGGGTTC
AATAGAAAATGTTTGTTTATGTTCACAAGATTCAATTGCGGTTTATCAAT
ATCATTTGAAATATTATGAATGCATACCTAAATTGTCTTTCAAAGACGTT
GGTTGTCAAAAATGTTATTCGAAAGGAGGTCAGTGCTATGTGAATAGTGT
CACGTCTCGGAAATTACAATGTGATTGTGGGAGACTTCGGATAAGTCAAT
TAAGAGACTTGAGGATTACAGACTCAGACGACGTCTGCAGCAGCAGTTTG
GTTTACATATCATGTAACTATAAAAGGCTACAAGTCTGTTACGTACCTCA
TAGTAATCCACCATATGGGAACTTGCAAAGTGCTCTTGATAAAAATCAAG
CCAAAGTTTTTCTCAGCAGTGATTCTTCGGAAAACGATGAAAGTCTTCCT
AATTTCAATAATGCATATCAAGAGAATGGAGAGTCATCATTTCACCATAA
CATGTGTCAGTTAAAGTTAATGCGTTCCCAAACGTCAACGCAAGACAAAT
ATTGCATAGATATATCGTTGAGATCAAGCGTCCTACCTTGCGGGCTCATT
CAAATGAAATACAAGAATGGAAATATGTATTCTGGTCTTCTTCAAATATG
GACTGACTCGAAATTTCCTACTCCGAGCCGTGACATGAAGTTCGAAATCA
ACTGCAAATCCCAGCCCAACAAACCCACAAACCAATTAGGCCAGTCCTTG
GACAGAACGGAGAGTATGTTTGGAAAAGACTTTTCAATATCCTCAAATGG
GGAATTTTTGTCGACTCCACAAATAACTTTGAAAATTCTAAATTCGTTGG
ATAATGAAATTACAACAATTGATATTGGAACTGCCATAAAAATCGACATT
CTTCTTGTGGATAGAAATGCTGAATTCAATGGAATTGAAGTTGAATCGTG
CTACGTCAGCAATATATCATTCAGTAAATTTGATCCGATCAAACATTCTG
AACAGTTCATCATTGACAGAGGATGCTCGGTTTCTAATTTTCCACTTTTT
CAAAATTTATTCTCTGACGCCAAGATTCCCTCTACACCAGTTCACTTGCA
AAGCAGCTTATTTCCCGCCTTTCAAGTATTTCCAAAGGATGAAAATGTTT
ATTACCGATGTCTTTTAAAAGTTTGTCGTCACACGACCTGGTGCAAGAAA
CCTACAAATTGTCAGGAAAAGTCTCATAGAAAATTTTCAATTAACAATGA
AGGCGATGTTAAATTTGTCGTACGGTCTATAAAATTGCAAGTGAGATCTT
TTGATGACAACATTTCGCCGGTGAGGATAAATCAAAGAAAAGAAAACTAC
AATCATGTCTGCCAGTATCCGATGTGTTTGAGTCTTGGACATTTATCGAT
GATAGCAGCGTCTTTTTCTATAATATTAATTCTGACAATTCTTTTACTAA
TTCTTCTTTATCGTAAACATTTCCATCATTTCAGATTATTTTCCCAATTA
TCAAGCGATACAAATCATAAAATTTGCACATACAATTCAAACAAAAACAT
ATTGAATGATGAACCCCTTAACAATATTGACGCTAATGATTGTTATAAAG
AATTCATGTATATAAATCCCCGTCAAATAATGAGTGATAACTATTATGAA
GACATTGTGACAGGATCTACAATCAACCCTCAATGGAGACTTGGTATATC
TAAACCATTGGTTATGAATGATATGGAGGTCAGCTATTGCCTCGATAACA
TGTATCTGGATAGCACTCATTCCTGCCTTCTCGATTCCTATCAAGAGCCC
ATATCCCCAGAAACAATGTCAAGATTTAATAATAGTAATAATAATAATAA
AGATCCAGGATCTATGAATATAAATCTTATTCCCAGTTCAAGTCTCTCGG
CTTTATCATCAGTGAATGAGACAGAAAATTATTATATTAAATTTCAAGAA
AAGGTTACAGGGCAAAGATTTTTTCCCGATTCAATGAAAATATCTGATTT
CAGTTCAGTGAAATCCTCTAAAAGTGAAGCAGGAGATCAGCAACACATTA
AAAAACATCTCATTCTGCCAGATCTTAGCAATAGCCGCCAAAATTCGCAA
TCTGCACCAAATTCTATTGAGACTATATCTGATTTAAACAAACAACCATT
GAGTCAGTCGACGGCTTCATTAGAATGCCCCGCTTATTCTCCGTCTTATC
CAACGAATGATGTCCGTCGAATTTCGAATAGTAGATCAATGGACCATATC
AACAGTTACGTGGCAAAACGCAATAATGATTACATTTCTAAAAGCTTTGA
TGATGATGCGTCTAAGTTTACCAAATCAGATAAATTAAAAAAGTGTGACA
GCAAATCAACTGTGGTAAATTCAACTCATAATTTACGTAAGAAATCAAAG
GGGTTGCTCAATTGTTTAAGTAATTCTAAAAATGTGCTTAACTTACAAAC
AACAGCCAATCAGAGACAGTGTAGTGTGTGCGGGAGACATTTTAATAGGT
CAGATATGCTTGCCAGGCACATGAGGGTTCATACCGGGCACAAGCCATTT
GAGTGCACAATATGTGGTCAATCCTTTTCAAGATCTGATCATTTAAATAC
ACATTTAAGAATACATTCAGGAGAAAAGCCATATCAATGCTCGATTTGCT
CCTATTCTGCATGCCGGAGGGATATGATTACTCGACATTTGAGAGTTCAC
AAACGGAAAGGGGATATAGTAACTGAAACCGGAACGTCTTTGGTAGTAAA
TGTAAACAAGCAGAAAACTACACAACACAAGAAAAAATCAAAATTAAAAG
CTCAGAACTCACTCAATATTGCCAGGGATGAATTGAATGACATGAAAGAG
TCCATATCTTCTTTGTATAGGTCAAGAAGTTTCACAGACGATGGCAGATG
TGTTGATTATGAAGATATTGATAATTCCTTGATAATATCCGATTCCCCAA
TAGAGAGACCCGTTTTACCTCCTCGAACGTTTGCTAATATCTCCATTTCT
ATTTCACAACCAACCCCCCGGAGCAGTTTTTCTATACCAATGGAAACACA
AAATTACGGATAAATCGTAACGATATTATTTCTTTATTGTTGTTTGGAGC
CAATATTTATTATTCGTTATTTTTCCTGGGATTTGTCTATTGTATCTGCA
TTTCGCTATCTTTATTTAGATGTATATTTATTTTTATGAAGACCATTTAT
TTGTCTGACGTTTTTTGATGTTTTCAATATTTACTTAACTAAAACTTATT
TGTTTATTTTATCGTTTGTGTCCGTTCACGTTCAATTACTTATTTCTCGT
GATAT
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protein sequence of SMED30033385-orf-1

>SMED30033385-orf-1 ID=SMED30033385-orf-1|Name=SMED30033385-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1216bp
MQYLWVSFYVIAINVQVQKSLVYQQPQNLAIGECAQDGDSYCLQRVPNSF
CSLEKNECFCKVGHVSVQDDGGTVCKPLLTNVKCRLDTDCTDVKGSICHP
GAGFCTCPEGTIFVPQRHQCMKRVHWSVQNNLCKACKNIKGTCFQEELDS
TNNDTTLKFGCLCSGKNAMPTKFIDDFSNVCEALLMDIGDFCNDQYLICR
SPKAVCKRRTGSIENVCLCSQDSIAVYQYHLKYYECIPKLSFKDVGCQKC
YSKGGQCYVNSVTSRKLQCDCGRLRISQLRDLRITDSDDVCSSSLVYISC
NYKRLQVCYVPHSNPPYGNLQSALDKNQAKVFLSSDSSENDESLPNFNNA
YQENGESSFHHNMCQLKLMRSQTSTQDKYCIDISLRSSVLPCGLIQMKYK
NGNMYSGLLQIWTDSKFPTPSRDMKFEINCKSQPNKPTNQLGQSLDRTES
MFGKDFSISSNGEFLSTPQITLKILNSLDNEITTIDIGTAIKIDILLVDR
NAEFNGIEVESCYVSNISFSKFDPIKHSEQFIIDRGCSVSNFPLFQNLFS
DAKIPSTPVHLQSSLFPAFQVFPKDENVYYRCLLKVCRHTTWCKKPTNCQ
EKSHRKFSINNEGDVKFVVRSIKLQVRSFDDNISPVRINQRKENYNHVCQ
YPMCLSLGHLSMIAASFSIILILTILLLILLYRKHFHHFRLFSQLSSDTN
HKICTYNSNKNILNDEPLNNIDANDCYKEFMYINPRQIMSDNYYEDIVTG
STINPQWRLGISKPLVMNDMEVSYCLDNMYLDSTHSCLLDSYQEPISPET
MSRFNNSNNNNKDPGSMNINLIPSSSLSALSSVNETENYYIKFQEKVTGQ
RFFPDSMKISDFSSVKSSKSEAGDQQHIKKHLILPDLSNSRQNSQSAPNS
IETISDLNKQPLSQSTASLECPAYSPSYPTNDVRRISNSRSMDHINSYVA
KRNNDYISKSFDDDASKFTKSDKLKKCDSKSTVVNSTHNLRKKSKGLLNC
LSNSKNVLNLQTTANQRQCSVCGRHFNRSDMLARHMRVHTGHKPFECTIC
GQSFSRSDHLNTHLRIHSGEKPYQCSICSYSACRRDMITRHLRVHKRKGD
IVTETGTSLVVNVNKQKTTQHKKKSKLKAQNSLNIARDELNDMKESISSL
YRSRSFTDDGRCVDYEDIDNSLIISDSPIERPVLPPRTFANISISISQPT
PRSSFSIPMETQNYG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0005634nucleus
GO:0005737cytoplasm
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR015880Znf_C2H2-like
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2
IPR001507ZP_dom
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
GO:0003677DNA binding
GO:0008270zinc ion binding
GO:0010385double-stranded methylated DNA binding
GO:0043565sequence-specific DNA binding
GO:0044729hemi-methylated DNA-binding
GO:1990841promoter-specific chromatin binding
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0043010camera-type eye development
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0048703embryonic viscerocranium morphogenesis
GO:0060059embryonic retina morphogenesis in camera-type eye
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001507Zona pellucida domainPROSITEPS51034ZP_2coord: 245..528
score: 15.16
NoneNo IPR availableTMHMMTMhelixcoord: 582..604