Nalp (Nacht leucine rich repeat and pyrin domain containing)

Overview
NameNalp (Nacht leucine rich repeat and pyrin domain containing)
Smed IDSMED30033369
Length (bp)1500
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Nalp (Nacht leucine rich repeat and pyrin domain containing) (SMED30033369) t-SNE clustered cells

Violin plots show distribution of expression levels for Nalp (Nacht leucine rich repeat and pyrin domain containing) (SMED30033369) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033369

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
testisSMED30033369SMESG000014919.1 DN311414.1ncbi_smed_estsPMID:22074376
Chong et al., 2011		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testis primordiumSMED30033369SMESG000014919.1 PL06010A1E04_SE3GPL10652PMID:20844018
Wang et al., 2010		whole organism juvenile cDNA to DNA expression microarray evidence
testisSMED30033369SMESG000014919.1 PL08003B2H02_SE3GPL10652PMID:20844018
Wang et al., 2010		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
early male germ cellSMED30033369SMESG000014919.1 PL08003B2H02_SE3GPL10652PMID:20844018
Wang et al., 2010		whole organism asexual adult cDNA to DNA expression microarray evidence
testis primordiumSMED30033369SMESG000014919.1 PL08003B2H02_SE3GPL10652PMID:20844018
Wang et al., 2010		whole organism juvenile cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Human
Match: NLRP12 (NLR family pyrin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:22938])

HSP 1 Score: 53.1434 bits (126), Expect = 1.205e-6
Identity = 44/127 (34.65%), Postives = 63/127 (49.61%), Query Frame = 1 
Query:  427 ELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKK-SIYLYTLSLNGCSISKLSGDKL-GDLVVNSTVRELYLDKNFLQSEG 801
            EL + G  +E   +  L   L   +  L  L L  C L A +   LA T+    +LREL L  NE GD GV +LC+ L+  +  L TL L+ C ++  + + L   L +N T+ +LYL  N L   G
Sbjct:  831 ELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTG 957
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Human
Match: CEP78 (centrosomal protein 78 [Source:HGNC Symbol;Acc:HGNC:25740])

HSP 1 Score: 50.0618 bits (118), Expect = 9.887e-6
Identity = 28/85 (32.94%), Postives = 44/85 (51.76%), Query Frame = 1 
Query:  508 LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVR 762
            L  LEL    L  + L ILA  + K  +L  L L     GD G+ ++CQ +K SI L T++  GC+++    D +  ++   T+R
Sbjct:  122 LKNLELNGLILRERDLTILAKGLNKSASLVHLSLANCPIGDGGLEIICQGIKSSITLKTVNFTGCNLTWQGADHMAKILKYQTMR 206
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Zebrafish
Match: si:ch211-202c21.7 (si:ch211-202c21.7 [Source:ZFIN;Acc:ZDB-GENE-081031-16])

HSP 1 Score: 62.7734 bits (151), Expect = 7.220e-11
Identity = 56/218 (25.69%), Postives = 92/218 (42.20%), Query Frame = 1 
Query:  115 AGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRK---IYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTV 759
            A +++   +  Y+  CL+ NS+    LK  I   +D  + L +  +   +  P+    D +LP +                        PLL  I+  RYT +QE  +W +  +  ++  L +L+ R+   +Y    LEL+DC L   S++ L   +   + L  L LDY   G  G+  L      S  + +LSL  C +   SG  L  L+ N  V
Sbjct:   15 AAQQLSALLGRYEHHCLQTNSSPSAELKLDILHHIDTQQPLRKITLSVPELEPS----DTLLPSL-----------------------QPLLMAIRDERYTHVQEFHIWSLSFKQTDVVELCFLMERRGTTVYPFRLLELLDCRLSEWSMKRLGKALATSY-LTTLCLDYTLVGQEGLKGLLSGGLGSGQICSLSLCYCGLGSWSGTLLASLLTNGPV 204
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Mouse
Match: Gm28729 (predicted gene 28729 [Source:MGI Symbol;Acc:MGI:5579435])

HSP 1 Score: 91.6633 bits (226), Expect = 1.758e-19
Identity = 65/228 (28.51%), Postives = 115/228 (50.44%), Query Frame = 1 
Query:  127 MKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYT---LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            ++KF+  Y   C++  +++   + + +K S+D  ++L +F++                  + +  SS S       +P   V + PLL  I+   YT  +E+ +WG+ +   EI+ LA  L +K +T   +  LE+IDC +D  SL  L   ++   +L  L+LDY +FG+  +  +   L+ +  L  LS+  C +   SG +LG ++ +S + EL LD N LQS G
Sbjct:   22 LQKFLKTYQKHCVQSRTSVCPAIHRDLKSSIDREQILGKFML------------------VRAGNSSAST------LP---VSLEPLLMTIRDEGYTLGKEICIWGLQLTNPEIARLALFLEQKGHTTCPVTTLEIIDCKMDLWSLGRLGKALQ-FSSLHFLVLDYCKFGNEELESIFSGLESNRRLQGLSMRYCGLGPQSGPRLGSVISHSGICELRLDGNHLQSSG 221
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Mouse
Match: Rnh1 (ribonuclease/angiogenin inhibitor 1 [Source:MGI Symbol;Acc:MGI:1195456])

HSP 1 Score: 49.6766 bits (117), Expect = 6.731e-6
Identity = 36/100 (36.00%), Postives = 55/100 (55.00%), Query Frame = 1 
Query:  508 LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKS-IYLYTLSLNGCSISKLSGDKLGDLVVN-STVRELYLDKNFLQSEG 801
            L KL+L  C L A S + LA  ++     +EL+L  N+  + GV +LCQ LK S   L +L L  C I+  +   L D+V + ++++EL L  N L + G
Sbjct:  175 LEKLQLEYCNLTATSCEPLASVLRVKADFKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAG 274
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Mouse
Match: Rnh1 (ribonuclease/angiogenin inhibitor 1 [Source:MGI Symbol;Acc:MGI:1195456])

HSP 1 Score: 49.2914 bits (116), Expect = 7.915e-6
Identity = 36/100 (36.00%), Postives = 55/100 (55.00%), Query Frame = 1 
Query:  508 LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKS-IYLYTLSLNGCSISKLSGDKLGDLVVN-STVRELYLDKNFLQSEG 801
            L KL+L  C L A S + LA  ++     +EL+L  N+  + GV +LCQ LK S   L +L L  C I+  +   L D+V + ++++EL L  N L + G
Sbjct:  139 LEKLQLEYCNLTATSCEPLASVLRVKADFKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAG 238
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Mouse
Match: Rnh1 (ribonuclease/angiogenin inhibitor 1 [Source:MGI Symbol;Acc:MGI:1195456])

HSP 1 Score: 49.2914 bits (116), Expect = 7.915e-6
Identity = 36/100 (36.00%), Postives = 55/100 (55.00%), Query Frame = 1 
Query:  508 LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKS-IYLYTLSLNGCSISKLSGDKLGDLVVN-STVRELYLDKNFLQSEG 801
            L KL+L  C L A S + LA  ++     +EL+L  N+  + GV +LCQ LK S   L +L L  C I+  +   L D+V + ++++EL L  N L + G
Sbjct:  139 LEKLQLEYCNLTATSCEPLASVLRVKADFKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAG 238
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Match: A0A1S8X8H4 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_01352 PE=4 SV=1)

HSP 1 Score: 268.855 bits (686), Expect = 5.459e-81
Identity = 171/450 (38.00%), Postives = 246/450 (54.67%), Query Frame = 1 
Query:  127 MKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESS------ISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEGXXXXXXXXXXXXKS------------------ANEST-PILDKSVKLKGLEMNVDQ-RFDPPSEYVP--GIIITGIENSKTSLDSPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLA 1392
            +K+ M  Y++   KY + +   ++KQ K+++D+ +L+ RF+VDP DR    +W+DE L      ++         +K  ++D P  LVKILPL++ I+  RYT IQELLVW   +E D+  ++A LLTR  Y + +LELIDCFLD+KS+  +   +    TL+EL LD+NE G+ G  +LC  L +  +L  LSL+ C ++K  G  LG+LV  + +REL LD N L++EGVIAL++ +  A ++                  A  +T PILD  + L G E N +    D PS   P  G  I   E+ K  + S  +          +E                    P   GP+I  L L+D  I   G    F PV CMQ LK +I+  RDL+EIDLFGN I ++ ARQILEG++ RK  + PQIG+RM H +NQD ++ I KLA
Sbjct:   23 LKELMRDYEIRAEKYETTVANSIRKQFKKALDDDRLVTRFVVDPQDRRVVEYWDDEKLVKALQGDADEGRRRRAKIKHVKEDKP--LVKILPLIDAIRARRYTHIQELLVWDCHVENDDALSIAGLLTRGCYPVSRLELIDCFLDSKSVGNIVTAVAVSKTLKELALDFNELGEKGCRILCTGLSRGRFLTHLSLSYCGLTKQCGLWLGNLVCETAIRELVLDGNPLEAEGVIALLSQLAEAAENEGFERAEEEKRRLKAIEDARRATRPILD--MDLSGFEQNANAGETDKPSSPAPSLGKPIAKPESGKAEIKSRKKRGKRGRKGGKLE--------------------PPPAGPQISVLKLADTGINHMGRGGNFAPVRCMQLLKSIISHSRDLQEIDLFGNAIGDLGARQILEGILTRKEAKLPQIGIRMGHRINQDTFDIIHKLA 448
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Match: A0A075A7P4 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_02156 PE=4 SV=1)

HSP 1 Score: 265.388 bits (677), Expect = 7.532e-80
Identity = 170/446 (38.12%), Postives = 243/446 (54.48%), Query Frame = 1 
Query:  139 MAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESS------ISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEGXXXXXXXXXXXXKS------------------ANEST-PILDKSVKLKGLEMNVDQ-RFDPPSEYVP--GIIITGIENSKTSLDSPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLA 1392
            M  Y++   KY + +   ++KQ K+++D+ +L+ RF+VDP DR    +W+DE L      ++         +K  ++D P  LVKILPL++ I+  RYT IQELLVW   +E D+  ++A LLTR  Y + +LELIDCFLD+KS+  +   +    TL+EL LD+NE G+ G  +LC  L +  +L  LSL+ C ++K  G  LG+LV  + +REL LD N L++EGVIAL++ +  A ++                  A  +T PILD  + L G E N +    D PS   P  G  I   E+ K  + S  +          +E                    P   GP+I  L L+D  I   G    F PV CMQ LK +I+  RDL+EIDLFGN I ++ ARQILEG++ RK  + PQIG+RM H +NQD ++ I KLA
Sbjct:    1 MRDYEIRAEKYETTVANSIRKQFKKALDDDRLVTRFVVDPQDRRVVEYWDDEKLVKALQGDADEGRRRRAKIKHVKEDKP--LVKILPLIDAIRARRYTHIQELLVWDCHVENDDALSIAGLLTRGCYPVSRLELIDCFLDSKSVGNIVTAVAVSKTLKELALDFNELGEKGCRILCTGLSRGKFLTHLSLSYCGLTKQCGLWLGNLVCETAIRELVLDGNPLEAEGVIALLSQLAEAAENEGFERAEEEKRRLKAIEDARRATRPILD--MDLSGFEQNANAGETDKPSSPAPSLGKPIAKPESGKAEIKSRKKRGKRGRKGGKLE--------------------PPPAGPQISVLKLADTGINHMGRGGNFAPVRCMQLLKSIISHSRDLQEIDLFGNAIGDLGARQILEGILTRKEAKLPQIGIRMGHRINQDTFDIIHKLA 422
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Match: A0A448X411 (Uncharacterized protein (Fragment) OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS20890 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 6.141e-49
Identity = 96/233 (41.20%), Postives = 146/233 (62.66%), Query Frame = 1 
Query:  127 MKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFS------PESSISVKKKRKDIPQN--LVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            MK+ +  YD+    Y ++  + +KK +K+++++ +LL +F+ DP DR    +W+DE     FS      P+S+   K++ K       LVK+LPL+E I+  RY  I E+LVW V +E  ++ ALA LL++ +Y + ++EL+DCF+DAKSL   AP++    TLR+L+LD+N FGD G  VLC  L    +L  LSL  C + K SG  LG+L+V + +RELYLD N L++EG
Sbjct:   28 MKELLKDYDMRAELYETSPCLAIKKTLKKAIEDERLLTKFIFDPQDRKQVEYWDDEKFIKYFSGEVEERPQSAKRKKQRPKSFKDEKPLVKLLPLIEAIRAKRYLNIHEILVWDVHLEDSDMYALAGLLSKSVYQIYRIELLDCFIDAKSLSTFAPSVALSKTLRDLVLDFNGFGDKGCKVLCTYLLTCKWLVHLSLCFCDLGKQSGFFLGNLIVETPIRELYLDGNSLEAEG 260
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Match: H2KUE9 (NACHT LRR and PYD domains-containing protein 9 OS=Clonorchis sinensis OX=79923 GN=CLF_108752 PE=4 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 2.887e-48
Identity = 95/231 (41.13%), Postives = 143/231 (61.90%), Query Frame = 1 
Query:  127 MKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRK------DIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            MK+ M  Y++   KY + +   ++KQ K+++D+ +L+ RF+VDP DR    +W+DE L      ++    ++K K      D P  LVKILPL++ I+  RYT IQELLVW   +E D+  ++A LLTR  Y + +LELIDCFLD+KS+  +   +    T++EL LD+NE G+ G  +LC  L +  +L  LSL+ C ++K  G  LG+LV  + +REL LD N L++EG
Sbjct:   23 MKELMRDYEIRAEKYETTVSNSIRKQFKKALDDDRLVTRFVVDPQDRRVVEYWDDEKLAKALQGDADEGRRRKAKIKHVKEDKP--LVKILPLIDAIRARRYTHIQELLVWDCHVENDDALSVAGLLTRGCYPVSRLELIDCFLDSKSVGNIVAAVAVSKTVKELALDFNELGEKGCRILCTGLSRGKFLTHLSLSYCGLTKQCGLWLGNLVCETAIRELNLDGNPLEAEG 251

HSP 2 Score: 110.153 bits (274), Expect = 2.950e-22
Identity = 52/99 (52.53%), Postives = 66/99 (66.67%), Query Frame = 1 
Query: 1096 PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLA 1392
            P   GP+I  L L+D  I   G    F PV CMQ LK +I+  RDL+EIDLFGN I ++ ARQILEG++ RK  + PQIG+RM H +NQD ++ I KLA
Sbjct:  334 PPPSGPQISVLKLADTGINHMGRGGNFAPVRCMQLLKSIISHSRDLQEIDLFGNAIGDLGARQILEGILTRKEAKLPQIGIRMGHRINQDTFDIIHKLA 432
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Match: A0A3R7GSW4 (Ribonuclease inhibitor OS=Clonorchis sinensis OX=79923 GN=RNH1 PE=4 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 2.887e-48
Identity = 95/231 (41.13%), Postives = 143/231 (61.90%), Query Frame = 1 
Query:  127 MKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRK------DIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            MK+ M  Y++   KY + +   ++KQ K+++D+ +L+ RF+VDP DR    +W+DE L      ++    ++K K      D P  LVKILPL++ I+  RYT IQELLVW   +E D+  ++A LLTR  Y + +LELIDCFLD+KS+  +   +    T++EL LD+NE G+ G  +LC  L +  +L  LSL+ C ++K  G  LG+LV  + +REL LD N L++EG
Sbjct:   23 MKELMRDYEIRAEKYETTVSNSIRKQFKKALDDDRLVTRFVVDPQDRRVVEYWDDEKLAKALQGDADEGRRRKAKIKHVKEDKP--LVKILPLIDAIRARRYTHIQELLVWDCHVENDDALSVAGLLTRGCYPVSRLELIDCFLDSKSVGNIVAAVAVSKTVKELALDFNELGEKGCRILCTGLSRGKFLTHLSLSYCGLTKQCGLWLGNLVCETAIRELNLDGNPLEAEG 251

HSP 2 Score: 110.153 bits (274), Expect = 3.006e-22
Identity = 52/99 (52.53%), Postives = 66/99 (66.67%), Query Frame = 1 
Query: 1096 PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLA 1392
            P   GP+I  L L+D  I   G    F PV CMQ LK +I+  RDL+EIDLFGN I ++ ARQILEG++ RK  + PQIG+RM H +NQD ++ I KLA
Sbjct:  334 PPPSGPQISVLKLADTGINHMGRGGNFAPVRCMQLLKSIISHSRDLQEIDLFGNAIGDLGARQILEGILTRKEAKLPQIGIRMGHRINQDTFDIIHKLA 432
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Cavefish
Match: ENSAMXT00000035476.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001659.1:105726:129056:-1 gene:ENSAMXG00000003048.2 transcript:ENSAMXT00000035476.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 3.118e-7
Identity = 47/132 (35.61%), Postives = 67/132 (50.76%), Query Frame = 1 
Query:  415 TFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFT-LRELILDYNEFGDAGVTVLCQELK-KSIYLYTLSLNGCSISKLSGDKLGD-LVVNSTVRELYLDKNFLQSEG 801
            +F++EL +    +    I+ L+ L+      L KL L  C L  K   +LA  +  C T LREL L  N+  D+GV +LC  LK +   L  L L GC+++K     L   L  NS++REL L +N L   G
Sbjct:  583 SFLKELDLTHNNLGESGINLLSALVKNPHCKLEKLLLRWCGLTLKVCDVLASALSLCTTCLRELDLSNNDLQDSGVILLCNGLKNEHCNLRILRLCGCNLTKHCCAALASVLSSNSSLRELDLSENNLDDSG 714
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Cavefish
Match: ENSAMXT00000053568.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000897.1:19354:51114:-1 gene:ENSAMXG00000030371.1 transcript:ENSAMXT00000053568.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.756e-6
Identity = 41/101 (40.59%), Postives = 52/101 (51.49%), Query Frame = 1 
Query:  508 LVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKK-SIYLYTLSLNGCSISK--LSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            L KL L DC L  KS   LA  +    TLRELIL YN+  D+GV +L   LK     L  L L GC++S+   +         +ST+R+L L  N LQ  G
Sbjct:  614 LEKLWLWDCNLSEKSCAALASALISNSTLRELILSYNKLQDSGVKLLSAGLKNPHCKLEKLQLAGCNLSEESCAALASALSSNSSTLRDLNLSNNELQDSG 714
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Nematostella
Match: EDO46032 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR11])

HSP 1 Score: 118.627 bits (296), Expect = 4.175e-29
Identity = 71/227 (31.28%), Postives = 120/227 (52.86%), Query Frame = 1 
Query:  121 EKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            E +K     Y+  C +  S +   +KK + Q  +++ LL +F++ P                   PE  + VK            + PLL  ++++RY +++EL +W + M+++++++LA  L + +Y +  LEL++C +D+ +++    +      L  L+LD+NEFGDAG   LC+ LK +  L  LSLN C +   SG  LGD V N+ +R+LYLD N L  EG
Sbjct:   30 ELLKAVRVNYESKCKEMKSYVHPEVKKLLNQYGEDNTLLAKFILTP------------------GPEDELPVK------------VQPLLAAMRVMRYIYLKELYIWDIPMKHEDVASLALFLEQPMYPVQYLELMECSIDSYAIERFGRSFM-FNNLTALVLDFNEFGDAGCAGLCKGLKANGTLLKLSLNYCGLGPHSGVILGDTVSNTAIRDLYLDGNKLGCEG 225

HSP 2 Score: 66.2402 bits (160), Expect = 9.155e-12
Identity = 33/88 (37.50%), Postives = 48/88 (54.55%), Query Frame = 1 
Query: 1117 ICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAI 1380
            I K+ L DN +  YG   T  P+ CM+  +KLIT    L+EIDL  N I ++  R+I+EGL +RK      I + + H +N   +  I
Sbjct:  327 IQKVHLLDNGVDSYGSASTLGPIMCMKMFRKLITHSEGLQEIDLDDNLIGDLGGREIMEGLTDRKEAGLNSIKMNVTHRMNPTTFANI 414
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Match: SMESG000014919.1 (SMESG000014919.1)

HSP 1 Score: 775.778 bits (2002), Expect = 0.000e+0
Identity = 448/450 (99.56%), Postives = 449/450 (99.78%), Query Frame = 1 
Query:   46 MAVXXXXXXXXXXXXXQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEGXXXXXXXXXXXXKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 1395
            MAVKGKKDKEKKSKAKQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSL+ILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLD NFLQSEGVIALVAAIVLAIKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLETPVETPVEVTVESPVETPVKKKKKKTKVAKVFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP
Sbjct:    1 MAVKGKKDKEKKSKAKQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLEILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDNNFLQSEGVIALVAAIVLAIKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLETPVETPVEVTVESPVETPVKKKKKKTKVAKVFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 450
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Match: SMESG000014919.1 (SMESG000014919.1)

HSP 1 Score: 743.421 bits (1918), Expect = 0.000e+0
Identity = 426/450 (94.67%), Postives = 431/450 (95.78%), Query Frame = 1 
Query:   46 MAVXXXXXXXXXXXXXQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEGXXXXXXXXXXXXKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFPLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 1395
            MAVKGKKDKEKKSKAKQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSL+ILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLD NFLQSEGVIALVAAIVLAIKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLETPVETPVEVTVESPVETP K+K++K                 L+LSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP
Sbjct:    1 MAVKGKKDKEKKSKAKQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLEILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDNNFLQSEGVIALVAAIVLAIKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPGIIITGIENSKTSLDSPLETPVETPVEVTVESPVETPRKRKRQKL----------------LNLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 434
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Match: SMESG000047177.1 (SMESG000047177.1)

HSP 1 Score: 209.149 bits (531), Expect = 9.475e-62
Identity = 112/241 (46.47%), Postives = 156/241 (64.73%), Query Frame = 1 
Query:   94 QMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSP-----ESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            Q    V A + +K+ +  YD+ C  Y +A  +PL++Q++   +ESK+L RFL+DP DR    +WED+ LP  F+P     E     KKK K   QNLVK+LPLLE ++  RY  IQEL VW VMM YD+I AL+ ++ R IY  V++EL+DCFLD+K L+ L P+I  C TL+E+ LD+NEFGD G   +C  L  + +L  LS+  C +SK SG  LG+LV  + +RE+YLD N L++EG
Sbjct:   21 QTGAAVDASKLLKELIKEYDVRCDVYCAAPCLPLRRQLRTFQEESKVLHRFLIDPKDRRKVEYWEDDDLPGQFAPIDILSELKKKPKKKGKKEHQNLVKVLPLLEALRNKRYIHIQELFVWEVMMAYDDICALSAMIARSIYQFVRIELVDCFLDSKCLEKLIPSINACRTLQEINLDFNEFGDEGCRTICTGLTGNRWLLQLSMCYCDLSKTSGLYLGELVAKTPIREIYLDGNELKAEG 261

HSP 2 Score: 109.768 bits (273), Expect = 1.231e-25
Identity = 50/100 (50.00%), Postives = 71/100 (71.00%), Query Frame = 1 
Query: 1096 PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 1395
            P  +GP+I K+ ++DN I + G    F P+ CMQ  K +I   +DLE+IDLFGNDI ++ +RQ+LEGLI RK  + PQIG+R+ H +NQD ++ I+KLAP
Sbjct:  349 PPPVGPQIEKIRVADNGIDQMGRGGNFAPMRCMQLFKTIIANAKDLEDIDLFGNDIGDLGSRQLLEGLILRKANKLPQIGIRVGHRINQDTFDLITKLAP 448
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Match: SMESG000045615.1 (SMESG000045615.1)

HSP 1 Score: 209.149 bits (531), Expect = 9.475e-62
Identity = 112/241 (46.47%), Postives = 156/241 (64.73%), Query Frame = 1 
Query:   94 QMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSP-----ESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            Q    V A + +K+ +  YD+ C  Y +A  +PL++Q++   +ESK+L RFL+DP DR    +WED+ LP  F+P     E     KKK K   QNLVK+LPLLE ++  RY  IQEL VW VMM YD+I AL+ ++ R IY  V++EL+DCFLD+K L+ L P+I  C TL+E+ LD+NEFGD G   +C  L  + +L  LS+  C +SK SG  LG+LV  + +RE+YLD N L++EG
Sbjct:   21 QTGAAVDASKLLKELIKEYDVRCDVYCAAPCLPLRRQLRTFQEESKVLHRFLIDPKDRRKVEYWEDDDLPGQFAPIDILSELKKKPKKKGKKEHQNLVKVLPLLEALRNKRYIHIQELFVWEVMMAYDDICALSAMIARSIYQFVRIELVDCFLDSKCLEKLIPSINACRTLQEINLDFNEFGDEGCRTICTGLTGNRWLLQLSMCYCDLSKTSGLYLGELVAKTPIREIYLDGNELKAEG 261

HSP 2 Score: 109.768 bits (273), Expect = 1.231e-25
Identity = 50/100 (50.00%), Postives = 71/100 (71.00%), Query Frame = 1 
Query: 1096 PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 1395
            P  +GP+I K+ ++DN I + G    F P+ CMQ  K +I   +DLE+IDLFGNDI ++ +RQ+LEGLI RK  + PQIG+R+ H +NQD ++ I+KLAP
Sbjct:  349 PPPVGPQIEKIRVADNGIDQMGRGGNFAPMRCMQLFKTIIANAKDLEDIDLFGNDIGDLGSRQLLEGLILRKANKLPQIGIRVGHRINQDTFDLITKLAP 448
[Close]
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Match: SMESG000047177.1 (SMESG000047177.1)

HSP 1 Score: 209.149 bits (531), Expect = 1.117e-61
Identity = 112/241 (46.47%), Postives = 156/241 (64.73%), Query Frame = 1 
Query:   94 QMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPLKKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSP-----ESSISVKKKRKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTRKIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTVLCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQSEG 801
            Q    V A + +K+ +  YD+ C  Y +A  +PL++Q++   +ESK+L RFL+DP DR    +WED+ LP  F+P     E     KKK K   QNLVK+LPLLE ++  RY  IQEL VW VMM YD+I AL+ ++ R IY  V++EL+DCFLD+K L+ L P+I  C TL+E+ LD+NEFGD G   +C  L  + +L  LS+  C +SK SG  LG+LV  + +RE+YLD N L++EG
Sbjct:   21 QTGAAVDASKLLKELIKEYDVRCDVYCAAPCLPLRRQLRTFQEESKVLHRFLIDPKDRRKVEYWEDDDLPGQFAPIDILSELKKKPKKKGKKEHQNLVKVLPLLEALRNKRYIHIQELFVWEVMMAYDDICALSAMIARSIYQFVRIELVDCFLDSKCLEKLIPSINACRTLQEINLDFNEFGDEGCRTICTGLTGNRWLLQLSMCYCDLSKTSGLYLGELVAKTPIREIYLDGNELKAEG 261

HSP 2 Score: 109.383 bits (272), Expect = 1.810e-25
Identity = 50/100 (50.00%), Postives = 71/100 (71.00%), Query Frame = 1 
Query: 1096 PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEIDLFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP 1395
            P  +GP+I K+ ++DN I + G    F P+ CMQ  K +I   +DLE+IDLFGNDI ++ +RQ+LEGLI RK  + PQIG+R+ H +NQD ++ I+KLAP
Sbjct:  348 PPPVGPQIEKIRVADNGIDQMGRGGNFAPMRCMQLFKTIIANAKDLEDIDLFGNDIGDLGSRQLLEGLILRKANKLPQIGIRVGHRINQDTFDLITKLAP 447
The following BLAST results are available for this feature:
BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
NLRP121.205e-634.65NLR family pyrin domain containing 12 [Source:HGNC... [more]
CEP789.887e-632.94centrosomal protein 78 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch211-202c21.77.220e-1125.69si:ch211-202c21.7 [Source:ZFIN;Acc:ZDB-GENE-081031... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Gm287291.758e-1928.51predicted gene 28729 [Source:MGI Symbol;Acc:MGI:55... [more]
Rnh16.731e-636.00ribonuclease/angiogenin inhibitor 1 [Source:MGI Sy... [more]
Rnh17.915e-636.00ribonuclease/angiogenin inhibitor 1 [Source:MGI Sy... [more]
Rnh17.915e-636.00ribonuclease/angiogenin inhibitor 1 [Source:MGI Sy... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S8X8H45.459e-8138.00Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A075A7P47.532e-8038.12Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A448X4116.141e-4941.20Uncharacterized protein (Fragment) OS=Protopolysto... [more]
H2KUE92.887e-4841.13NACHT LRR and PYD domains-containing protein 9 OS=... [more]
A0A3R7GSW42.887e-4841.13Ribonuclease inhibitor OS=Clonorchis sinensis OX=7... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSAMXT00000035476.13.118e-735.61pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000053568.11.756e-640.59pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO460324.175e-2931.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nalp (Nacht leucine rich repeat and pyrin domain containing) vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000014919.10.000e+099.56SMESG000014919.1[more]
SMESG000014919.10.000e+094.67SMESG000014919.1[more]
SMESG000047177.19.475e-6246.47SMESG000047177.1[more]
SMESG000045615.19.475e-6246.47SMESG000045615.1[more]
SMESG000047177.11.117e-6146.47SMESG000047177.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033369 ID=SMED30033369|Name=Nalp (Nacht leucine rich repeat and pyrin domain containing)|organism=Schmidtea mediterranea sexual|type=transcript|length=1500bp
TTAAAATTTAATTAATACAAATCTGCCTTTCAAGCTTCAAACCAGATGGC
CGTCAAGGGTAAAAAAGATAAGGAGAAAAAATCAAAAGCTAAACAAATGC
AAAATATGGTTTATGCGGGAGAAAAAATGAAAAAGTTTATGGCCATGTAT
GATCTGCTCTGTCTGAAATACAACAGCGCGATTTTCATTCCTTTGAAGAA
GCAGATCAAGCAAAGCATGGATGAATCAAAACTTCTCTTGAGGTTTCTAG
TTGATCCTCTTGACAGAACACCGACGTACTTCTGGGAAGATGAAATGCTG
CCTGATATATTTTCACCAGAATCCAGCATCAGTGTCAAGAAAAAGAGAAA
AGATATTCCGCAAAATTTAGTTAAGATTTTGCCATTACTCGAATGTATTA
AGATGGTTCGGTATACTTTCATACAAGAACTACTTGTCTGGGGTGTGATG
ATGGAATATGATGAAATATCAGCTTTGGCATATCTTCTTACTAGAAAAAT
ATACACCCTTGTCAAATTGGAGCTGATTGACTGTTTCCTTGACGCTAAAT
CTCTGCAAATATTGGCACCAACGATAAAAAAATGTTTCACTTTAAGAGAG
CTGATTTTAGATTACAATGAATTTGGAGACGCGGGCGTTACTGTCCTCTG
CCAGGAGCTAAAGAAAAGTATTTATTTATATACTTTAAGTCTCAATGGAT
GCTCAATATCAAAGCTCAGTGGAGACAAATTGGGAGATCTGGTCGTAAAC
AGTACAGTTCGGGAGCTCTATTTGGACAAAAATTTCCTGCAAAGTGAAGG
GGTAATTGCGCTTGTCGCAGCCATCGTATTGGCTATTAAATCTGCCAATG
AATCGACGCCTATTTTGGACAAGAGCGTAAAACTTAAAGGACTGGAAATG
AATGTTGACCAGCGGTTTGATCCTCCGTCAGAATATGTCCCCGGCATCAT
CATCACTGGTATCGAAAATAGTAAAACATCATTAGATTCGCCGTTAGAAA
CTCCTGTAGAAACGCCAGTTGAGGTGACAGTAGAATCCCCAGTAGAAACA
CCAGTAAAAAAGAAAAAGAAAAAGACAAAAGTTGCTAAAGTGTTTCCTTT
AGTTCTTGGTCCAGAAATATGTAAATTAAGTTTATCTGATAACAGAATAG
GCCGATATGGACTATGGCAAACCTTCACGCCAGTCTTTTGCATGCAACAA
TTGAAAAAACTTATTACAACCTGCAGGGATCTAGAAGAAATTGATTTATT
TGGAAACGATATCAGTAACATCGCAGCAAGACAAATATTGGAAGGTCTTA
TTGAAAGAAAGAACAAACGATATCCGCAGATTGGCGTGAGAATGTGTCAC
ATTTTGAATCAAGATATGTATGAAGCGATTTCTAAACTTGCTCCCGGTTC
GAAGAAAAAGAAGAAAGGCTCCAAAAAGAATTAAAATAGAAAAATATAAA
ATTTATTTACTTATGTTATACAGAATAAACGTAAATGAGCAGATCGGAAG
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protein sequence of SMED30033369-orf-1

>SMED30033369-orf-1 ID=SMED30033369-orf-1|Name=SMED30033369-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=463bp
MAVKGKKDKEKKSKAKQMQNMVYAGEKMKKFMAMYDLLCLKYNSAIFIPL
KKQIKQSMDESKLLLRFLVDPLDRTPTYFWEDEMLPDIFSPESSISVKKK
RKDIPQNLVKILPLLECIKMVRYTFIQELLVWGVMMEYDEISALAYLLTR
KIYTLVKLELIDCFLDAKSLQILAPTIKKCFTLRELILDYNEFGDAGVTV
LCQELKKSIYLYTLSLNGCSISKLSGDKLGDLVVNSTVRELYLDKNFLQS
EGVIALVAAIVLAIKSANESTPILDKSVKLKGLEMNVDQRFDPPSEYVPG
IIITGIENSKTSLDSPLETPVETPVEVTVESPVETPVKKKKKKTKVAKVF
PLVLGPEICKLSLSDNRIGRYGLWQTFTPVFCMQQLKKLITTCRDLEEID
LFGNDISNIAARQILEGLIERKNKRYPQIGVRMCHILNQDMYEAISKLAP
GSKKKKKGSKKN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000208testis
PLANA:0002030early male germ cell
PLANA:0003304testis primordium
Vocabulary: INTERPRO
TermDefinition
IPR001611Leu-rich_rpt
IPR032675LRR_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm