FAD-binding PCMH-type domain-containing protein

Overview
NameFAD-binding PCMH-type domain-containing protein
Smed IDSMED30033367
Length (bp)1781
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of FAD-binding PCMH-type domain-containing protein (SMED30033367) t-SNE clustered cells

Violin plots show distribution of expression levels for FAD-binding PCMH-type domain-containing protein (SMED30033367) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033367

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30033367SMESG000022021.1 dd_Smed_v4_21866_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033367SMESG000022021.1 dd_Smed_v4_21866_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30033367SMESG000022021.1 dd_Smed_v4_21866_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Match: DHCR24 (24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859])

HSP 1 Score: 295.434 bits (755), Expect = 1.798e-96
Identity = 160/382 (41.88%), Postives = 231/382 (60.47%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L++++   +   ++YPI + P    F  PS+  L +PK       ++  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ +K    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKF----THESQRQEN--HFVEGLLYSLDEAVIMTGVMTDEAEPSK---LNSIGNYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GNEAELYIDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKI 510

HSP 2 Score: 79.337 bits (194), Expect = 1.798e-96
Identity = 47/118 (39.83%), Postives = 66/118 (55.93%), Query Frame = 2 
Query:  161 RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   31 RWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Match: DHCR24 (24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859])

HSP 1 Score: 295.434 bits (755), Expect = 1.798e-96
Identity = 160/382 (41.88%), Postives = 231/382 (60.47%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L++++   +   ++YPI + P    F  PS+  L +PK       ++  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ +K    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKF----THESQRQEN--HFVEGLLYSLDEAVIMTGVMTDEAEPSK---LNSIGNYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GNEAELYIDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKI 510

HSP 2 Score: 79.337 bits (194), Expect = 1.798e-96
Identity = 47/118 (39.83%), Postives = 66/118 (55.93%), Query Frame = 2 
Query:  161 RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   31 RWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Match: DHCR24 (24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859])

HSP 1 Score: 286.96 bits (733), Expect = 6.134e-94
Identity = 160/394 (40.61%), Postives = 231/394 (58.63%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEA------------IIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+             IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L++++   +   ++YPI + P    F  PS+  L +PK       ++  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ +K    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKF----THESQRQEN--HFVEGLLYSLDEAVIMTGVMTDEAEPSK---LNSIGNYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQLLCFSVSDVPQRDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GNEAELYIDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKI 522

HSP 2 Score: 79.337 bits (194), Expect = 6.134e-94
Identity = 47/120 (39.17%), Postives = 66/120 (55.00%), Query Frame = 2 
Query:  155 EHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
              R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   29 HQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Match: DHCR24 (24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859])

HSP 1 Score: 55.4546 bits (132), Expect = 1.443e-16
Identity = 30/72 (41.67%), Postives = 43/72 (59.72%), Query Frame = 2 
Query:  299 QVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            QVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   36 QVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 105

HSP 2 Score: 51.6026 bits (122), Expect = 1.443e-16
Identity = 24/44 (54.55%), Postives = 30/44 (68.18%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIH 675
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+ 
Sbjct:  117 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVR 160
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Match: DHCR24 (24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859])

HSP 1 Score: 56.225 bits (134), Expect = 8.822e-16
Identity = 27/55 (49.09%), Postives = 37/55 (67.27%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLY 708
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L+
Sbjct:   69 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTP-SENSDLF 122

HSP 2 Score: 47.7506 bits (112), Expect = 8.822e-16
Identity = 25/57 (43.86%), Postives = 34/57 (59.65%), Query Frame = 2 
Query:  344 LCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:    1 MCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 57
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Celegans
Match: Y7A5A.1 (pep chromosome:WBcel235:X:15767437:15771509:-1 gene:WBGene00012407.1 transcript:Y7A5A.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y7A5A.1)

HSP 1 Score: 466.848 bits (1200), Expect = 1.489e-164
Identity = 214/408 (52.45%), Postives = 296/408 (72.55%), Query Frame = 1 
Query:  517 KKVVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQ--NPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFVL 1734
            K   LA TLEI DAT GGLA GVGMTT+SHKVGL+QE++VSY +V +DG+ I V   NEHS+L++CLPWSHG+LGFLV L L+I+    Y+ + Y P    + YC ++   SGA +  N  + D+LE T++  +E+VI+ G+F ++ + + N  +ND+  +YKPWFYKHVE+FLKK        GEE IP++ YL RHNR+IFWV+E++IPF N+P+FR F GW+CPPKPAFLKFTTT  +R  TF KQVFQDIV+P+  L+E ++ + KLF+ YP+L+YPC+++       +G LR P   ++   ++Y MF DLGVYG P  ++ ++ Y+P+ AMR+MEKF RD GGYSFLYADIFM++EEF EMFD++ Y ++  +YH D AFP LYDKVKPE+DV+ + + + +
Sbjct:  136 KGYTLAVTLEIGDATLGGLAFGVGMTTYSHKVGLYQEAIVSYEVVTADGNVITVTDSNEHSDLFYCLPWSHGTLGFLVGLTLRIVKVKPYVHMEYIPCHSQDEYCKKIMELSGA-TDKNTKVADYLEVTIYDKNEAVIMVGNFADVDSKS-NAKVNDVCWFYKPWFYKHVETFLKK-------GGEEYIPLESYLLRHNRAIFWVVESMIPFGNHPVFRAFLGWLCPPKPAFLKFTTTQAVREMTFAKQVFQDIVMPLDTLKEQVDTAVKLFDTYPLLVYPCRIYDHKGGAPQGQLRAPPKSRLVPGTNYSMFNDLGVYGTPGQVERREPYNPTHAMRAMEKFTRDVGGYSFLYADIFMSEEEFNEMFDMTLYNQVRLRYHCDGAFPRLYDKVKPEIDVISIGETYAV 534

HSP 2 Score: 133.265 bits (334), Expect = 1.489e-164
Identity = 64/131 (48.85%), Postives = 91/131 (69.47%), Query Frame = 2 
Query:  128 KVVSCEFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            K  +  +LE++RGLV+V+FCLPASF+F L I FR +L +  S  + SH  RV+KIQ QV +W+++P   +K LC +RPNWLSLSTTFF K +C ++ I L  +L  +E   TVTVEP +TV +I  +L+ +
Sbjct:    7 KAKAIRWLEDNRGLVIVLFCLPASFLFDLFIQFRIWLDRKLSA-TTSHQQRVQKIQDQVTEWSKLPDSEQKPLCTARPNWLSLSTTFFDKRKCHQVPIDLHDVLSLDEKNLTVTVEPNITVREICKFLIPK 136
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Celegans
Match: Y7A5A.1 (pep chromosome:WBcel235:X:15767437:15771493:-1 gene:WBGene00012407.1 transcript:Y7A5A.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y7A5A.1)

HSP 1 Score: 466.848 bits (1200), Expect = 1.489e-164
Identity = 214/408 (52.45%), Postives = 296/408 (72.55%), Query Frame = 1 
Query:  517 KKVVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQ--NPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFVL 1734
            K   LA TLEI DAT GGLA GVGMTT+SHKVGL+QE++VSY +V +DG+ I V   NEHS+L++CLPWSHG+LGFLV L L+I+    Y+ + Y P    + YC ++   SGA +  N  + D+LE T++  +E+VI+ G+F ++ + + N  +ND+  +YKPWFYKHVE+FLKK        GEE IP++ YL RHNR+IFWV+E++IPF N+P+FR F GW+CPPKPAFLKFTTT  +R  TF KQVFQDIV+P+  L+E ++ + KLF+ YP+L+YPC+++       +G LR P   ++   ++Y MF DLGVYG P  ++ ++ Y+P+ AMR+MEKF RD GGYSFLYADIFM++EEF EMFD++ Y ++  +YH D AFP LYDKVKPE+DV+ + + + +
Sbjct:  136 KGYTLAVTLEIGDATLGGLAFGVGMTTYSHKVGLYQEAIVSYEVVTADGNVITVTDSNEHSDLFYCLPWSHGTLGFLVGLTLRIVKVKPYVHMEYIPCHSQDEYCKKIMELSGA-TDKNTKVADYLEVTIYDKNEAVIMVGNFADVDSKS-NAKVNDVCWFYKPWFYKHVETFLKK-------GGEEYIPLESYLLRHNRAIFWVVESMIPFGNHPVFRAFLGWLCPPKPAFLKFTTTQAVREMTFAKQVFQDIVMPLDTLKEQVDTAVKLFDTYPLLVYPCRIYDHKGGAPQGQLRAPPKSRLVPGTNYSMFNDLGVYGTPGQVERREPYNPTHAMRAMEKFTRDVGGYSFLYADIFMSEEEFNEMFDMTLYNQVRLRYHCDGAFPRLYDKVKPEIDVISIGETYAV 534

HSP 2 Score: 133.265 bits (334), Expect = 1.489e-164
Identity = 64/131 (48.85%), Postives = 91/131 (69.47%), Query Frame = 2 
Query:  128 KVVSCEFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            K  +  +LE++RGLV+V+FCLPASF+F L I FR +L +  S  + SH  RV+KIQ QV +W+++P   +K LC +RPNWLSLSTTFF K +C ++ I L  +L  +E   TVTVEP +TV +I  +L+ +
Sbjct:    7 KAKAIRWLEDNRGLVIVLFCLPASFLFDLFIQFRIWLDRKLSA-TTSHQQRVQKIQDQVTEWSKLPDSEQKPLCTARPNWLSLSTTFFDKRKCHQVPIDLHDVLSLDEKNLTVTVEPNITVREICKFLIPK 136
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Celegans
Match: F52H2.6 (Diminuto-like protein [Source:UniProtKB/Swiss-Prot;Acc:O17397])

HSP 1 Score: 251.521 bits (641), Expect = 8.717e-86
Identity = 140/390 (35.90%), Postives = 207/390 (53.08%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHV--------EKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL  G G+ + S K G+FQ     Y +V+SDG   +V        E+  + ++L+  +PWS G++ FLV+  +KII    Y+KL Y+    +   C Q+      +S  N    DF+EA +F+ ++  I+ G+F +    T +  +N I +WYK WFY HVE  + K          E IP++DY  RH++SIFW L  I+PF NN LFR    WMCPPK AFLK TT   +R       V QD+++P+  LEE I+L  K   IYP+ + P   F+     GL++         ++ + M+ D+G YGV      K  Y   +  R +E F+R   G+   YADI+M + E+ EMFD + Y+         +AFP +YDK+
Sbjct:  154 ELDDLTVGGLINGCGVESGSFKYGMFQHICTGYEVVMSDGELKNVYPDSAAKTEQAKQDNSLFFAIPWSQGTICFLVAATIKIIPCKKYVKLTYKKTETLSEMCEQL----TEDSDRNSENVDFVEALMFNKEKGCIMLGEFSD-GPDTHDEVVNPIGRWYKKWFYTHVEDLINKK-----HESIEYIPLRDYYHRHSKSIFWELRDIVPFGNNVLFRYLMAWMCPPKIAFLKATTPNVLRKLYDRSHVLQDMLVPLDKLEECIDLFHKEVEIYPMWLCP---FYLKSQPGLMK-------LRNATHKMYVDVGAYGVTS----KDGYHHERTTRRLESFVRSVNGFQMTYADIYMTRAEYAEMFDRTLYDWKRASCKCIDAFPDIYDKI 519

HSP 2 Score: 86.2705 bits (212), Expect = 8.717e-86
Identity = 50/129 (38.76%), Postives = 79/129 (61.24%), Query Frame = 2 
Query:  143 EFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTF-FKKEECQKIEIP-LFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            EF+  H R + VV F LP SF+F  + +FR  +V   +    +H+ +V+ IQ+Q+++WN+  ++++  L N+RP WL++S  F   KE   KI    LF IL+ +  K TV  EP VT+GQ++ YL+ R
Sbjct:   19 EFIMFHFRWVFVVPFLLPLSFLFNTVFDFRNRIVHAVNSAPNAHVRKVKHIQEQLKEWNDNGRKSK--LVNARPGWLTMSFRFPLYKENATKIATDKLFDILDLDVEKMTVKAEPGVTMGQLSQYLISR 145
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Zebrafish
Match: dhcr24 (24-dehydrocholesterol reductase [Source:ZFIN;Acc:ZDB-GENE-041212-73])

HSP 1 Score: 277.33 bits (708), Expect = 3.624e-90
Identity = 151/382 (39.53%), Postives = 229/382 (59.95%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SH  GLFQ   V++ LVL+DGS +    + E+S+L++ +PWS G+LGFLV+ E++II A  ++KL Y PV G++  C +       ES+  +N   F+E   +S DE+VI+ G   +   H +    N I  +YKPWF++HVESFLK+   A      E IP++ Y  RH RSIFW L+ IIPF NNPLFR  FGWM PPK + LK T    IR       V QD+++PM  ++ +I+   +  ++YP+ + P    F  P++  + +PK      D D  ++ D+G YG P+     + ++ + + R +EKF+RD  G+  LYAD++M ++EF EMFD + Y K+ ++    +AFP ++DK+
Sbjct:  158 ELDDLTVGGLVMGTGIESSSHIYGLFQHICVAFELVLADGSLVRC-TEKENSDLFYAVPWSCGTLGFLVAAEIRIIPAQKWVKLHYEPVRGLDAICKKF----AEESANKEN--QFVEGLQYSRDEAVIMTGVMTD---HAEPDKTNCIGYYYKPWFFRHVESFLKQNRVA-----VEYIPLRHYYHRHTRSIFWELQDIIPFGNNPLFRYVFGWMVPPKISLLKLTQGETIRKLYEQHHVVQDMLVPMKDIKAAIQRFHEDIHVYPLWLCP----FLLPNQPGMVHPKG-----DED-ELYVDIGAYGEPKV----KHFEATSSTRQLEKFVRDVHGFQMLYADVYMERKEFWEMFDGTLYHKLREELGCKDAFPEVFDKI 510

HSP 2 Score: 75.485 bits (184), Expect = 3.624e-90
Identity = 45/130 (34.62%), Postives = 69/130 (53.08%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            KV   E++  H R + V +F LP S VF +  + R +++         H  RVR IQ+QVR+W +     +K +C  RP WL++S    K ++  K I I +  ILE +  ++ V VEP   +GQ+T  L
Sbjct:   19 KVKGLEYVIIHQRWIFVCLFLLPLSVVFDVYYHLRAWIIFKMCSAPKQHDQRVRDIQRQVREWRK--DGGKKYMCTGRPGWLTVSLRVGKYKKTHKNIMINMMDILEVDTKQKVVRVEPLANMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Zebrafish
Match: dhcr24 (24-dehydrocholesterol reductase [Source:ZFIN;Acc:ZDB-GENE-041212-73])

HSP 1 Score: 153.68 bits (387), Expect = 3.965e-53
Identity = 84/199 (42.21%), Postives = 121/199 (60.80%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEA 1140
            E+ D T GGL MG G+ + SH  GLFQ   V++ LVL+DGS +    + E+S+L++ +PWS G+LGFLV+ E++II A  ++KL Y PV G++  C +       ES+  +N   F+E   +S DE+VI+ G   +   H +    N I  +YKPWF++HVESFLK+   A      E IP++ Y  RH RSIFW L+ 
Sbjct:  158 ELDDLTVGGLVMGTGIESSSHIYGLFQHICVAFELVLADGSLVRC-TEKENSDLFYAVPWSCGTLGFLVAAEIRIIPAQKWVKLHYEPVRGLDAICKKF----AEESANKEN--QFVEGLQYSRDEAVIMTGVMTD---HAEPDKTNCIGYYYKPWFFRHVESFLKQNRVA-----VEYIPLRHYYHRHTRSIFWELQV 341

HSP 2 Score: 75.8702 bits (185), Expect = 3.965e-53
Identity = 45/130 (34.62%), Postives = 69/130 (53.08%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            KV   E++  H R + V +F LP S VF +  + R +++         H  RVR IQ+QVR+W +     +K +C  RP WL++S    K ++  K I I +  ILE +  ++ V VEP   +GQ+T  L
Sbjct:   19 KVKGLEYVIIHQRWIFVCLFLLPLSVVFDVYYHLRAWIIFKMCSAPKQHDQRVRDIQRQVREWRK--DGGKKYMCTGRPGWLTVSLRVGKYKKTHKNIMINMMDILEVDTKQKVVRVEPLANMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Xenopus
Match: dhcr24 (24-dehydrocholesterol reductase [Source:NCBI gene;Acc:549554])

HSP 1 Score: 283.108 bits (723), Expect = 3.414e-91
Identity = 154/384 (40.10%), Postives = 230/384 (59.90%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEA--IIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D   GGL MG G+ + SH  GLFQ   ++Y LVL+DGS +      E+S+L++ +PWS G+LGFLV+ E+KI+ A  Y+KL Y PV G+E  C +    S  + +Y      F+E  V+S DE+VI+ G   +     +   +N I +++KPWF++HVES+LK   N DG    E IP++ Y  RH +SIFW L+   IIPF N+P+FR FFGWM PPK + LK T    IR       V QD+++PM  L+++I       ++YP+ + P    F  PS   + +PK       ++  ++ D+G YG P+     + +D   +MR +EKF+RD  G+  LYAD +M++EEF +MFD + Y+K+  K + +NAFP +YDK+
Sbjct:  158 ELDDLKIGGLIMGTGIESSSHNFGLFQHICLAYELVLADGSLVRC-TPTENSDLFYAVPWSCGTLGFLVAAEIKIVPAKKYVKLHYTPVKGLEKICEKFSRESKNKENY------FVEGLVYSADEAVIMTGVLTD---EAQAGQVNRIGQYWKPWFFRHVESYLKN--NRDG---TEYIPLRHYYHRHTKSIFWELQVHDIIPFGNHPVFRYFFGWMVPPKISLLKLTQGETIRKLYEQHHVVQDMLVPMKCLQKAITAFHSEISVYPLWLCP----FILPSHPGMIHPK------GNEAELYVDIGAYGEPKT----KHFDAKGSMRRLEKFVRDVHGFQMLYADCYMSREEFWDMFDGALYQKLRGKLNCNNAFPEVYDKI 512

HSP 2 Score: 73.559 bits (179), Expect = 3.414e-91
Identity = 43/120 (35.83%), Postives = 61/120 (50.83%), Query Frame = 2 
Query:  155 EHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
             HR + V +F LP S +F +    R +LV         H  RV+ IQ QVR+W    +  +  +C  RP WL++S    K +   K I I L  ILE +  ++ V VEP V +GQ+T  L
Sbjct:   29 HHRWIFVCLFLLPLSVIFDVYYYARAWLVFKMCSAPKQHDRRVKDIQDQVRQWKA--EGGKNFMCTGRPGWLTVSLRVGKYKNTHKNIMINLMDILEVDTKRQPVRVEPLVNMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Mouse
Match: Dhcr24 (24-dehydrocholesterol reductase [Source:MGI Symbol;Acc:MGI:1922004])

HSP 1 Score: 289.656 bits (740), Expect = 6.000e-95
Identity = 157/382 (41.10%), Postives = 229/382 (59.95%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y L+L+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  + +++   +   ++YPI + P    F  PS+  L +PK        +  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ ++    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELILADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKF----TRESQRLEN--HFVEGLLYSLDEAVIMTGVMTDDVEPSK---LNSIGSYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCMSQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GDEAELYVDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKI 510

HSP 2 Score: 78.9518 bits (193), Expect = 6.000e-95
Identity = 50/130 (38.46%), Postives = 72/130 (55.38%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            +V   EF+  H R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP V++GQ+T  L
Sbjct:   19 RVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q60HC5|DHC24_MACFA (Delta(24)-sterol reductase OS=Macaca fascicularis OX=9541 GN=DHCR24 PE=2 SV=2)

HSP 1 Score: 294.664 bits (753), Expect = 6.138e-96
Identity = 160/382 (41.88%), Postives = 231/382 (60.47%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L++++   +   ++YPI + P    F  PS+  L +PK       ++  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ +K    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVQGLEAICAKF----THESQRQEN--HFVEGLLYSLDEAVIMTGVMTDEVEPSK---LNSIGNYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GNEAELYIDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKI 510

HSP 2 Score: 80.1073 bits (196), Expect = 6.138e-96
Identity = 51/130 (39.23%), Postives = 72/130 (55.38%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            +V   EF+  H R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   19 RVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q15392|DHC24_HUMAN (Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2)

HSP 1 Score: 295.434 bits (755), Expect = 7.876e-96
Identity = 160/382 (41.88%), Postives = 231/382 (60.47%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y LVL+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L++++   +   ++YPI + P    F  PS+  L +PK       ++  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ +K    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKF----THESQRQEN--HFVEGLLYSLDEAVIMTGVMTDEAEPSK---LNSIGNYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GNEAELYIDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKI 510

HSP 2 Score: 79.337 bits (194), Expect = 7.876e-96
Identity = 47/118 (39.83%), Postives = 66/118 (55.93%), Query Frame = 2 
Query:  161 RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP VT+GQ+T  L
Sbjct:   31 RWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VCH6|DHC24_MOUSE (Delta(24)-sterol reductase OS=Mus musculus OX=10090 GN=Dhcr24 PE=1 SV=1)

HSP 1 Score: 289.656 bits (740), Expect = 3.629e-94
Identity = 157/382 (41.10%), Postives = 229/382 (59.95%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y L+L+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  + +++   +   ++YPI + P    F  PS+  L +PK        +  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ ++    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELILADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKF----TRESQRLEN--HFVEGLLYSLDEAVIMTGVMTDDVEPSK---LNSIGSYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCMSQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GDEAELYVDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKI 510

HSP 2 Score: 78.9518 bits (193), Expect = 3.629e-94
Identity = 50/130 (38.46%), Postives = 72/130 (55.38%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            +V   EF+  H R + V +F LP S +F +    R ++V   S     H  RVR IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP V++GQ+T  L
Sbjct:   19 RVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5BQE6|DHC24_RAT (Delta(24)-sterol reductase OS=Rattus norvegicus OX=10116 GN=Dhcr24 PE=2 SV=2)

HSP 1 Score: 290.426 bits (742), Expect = 8.260e-94
Identity = 158/382 (41.36%), Postives = 229/382 (59.95%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ    +Y L+L+DGSF+     +E+S+L++ +PWS G+LGFLV+ E++II A  Y+KLR+ PV G+E  C +       ES   +N   F+E  ++S DE+VI+ G   +    +K   +N I  +YKPWF+KHVE++LK   N +G    E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    +R       V QD+++PM  L +++   +   ++YPI + P    F  PS+  L +PK        +  ++ D+G YG PR     + ++    MR +EKF+R   G+  LYAD +MN+EEF EMFD S Y K+ ++    +AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELILADGSFVRC-TPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKF----THESQRLEN--HFVEGLLYSLDEAVIMTGVMTDDVEPSK---LNSIGSYYKPWFFKHVENYLKT--NREGL---EYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLSQALHTFQNDIHVYPIWLCP----FILPSQPGLVHPK------GDEAELYVDIGAYGEPRV----KHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKI 510

HSP 2 Score: 77.411 bits (189), Expect = 8.260e-94
Identity = 49/130 (37.69%), Postives = 72/130 (55.38%), Query Frame = 2 
Query:  128 KVVSCEFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            +V   EF+  H R + V +F LP S +F +    R ++V   S     H  RV+ IQKQVR+W E  + ++  +C  RP WL++S    K ++  K I I L  ILE +  K+ V VEP V++GQ+T  L
Sbjct:   19 RVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVQDIQKQVREWKE--QGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Match: sp|O17397|DIML_CAEEL (Diminuto-like protein OS=Caenorhabditis elegans OX=6239 GN=F52H2.6 PE=3 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 9.061e-85
Identity = 140/390 (35.90%), Postives = 207/390 (53.08%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHV--------EKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL  G G+ + S K G+FQ     Y +V+SDG   +V        E+  + ++L+  +PWS G++ FLV+  +KII    Y+KL Y+    +   C Q+      +S  N    DF+EA +F+ ++  I+ G+F +    T +  +N I +WYK WFY HVE  + K          E IP++DY  RH++SIFW L  I+PF NN LFR    WMCPPK AFLK TT   +R       V QD+++P+  LEE I+L  K   IYP+ + P   F+     GL++         ++ + M+ D+G YGV      K  Y   +  R +E F+R   G+   YADI+M + E+ EMFD + Y+         +AFP +YDK+
Sbjct:  154 ELDDLTVGGLINGCGVESGSFKYGMFQHICTGYEVVMSDGELKNVYPDSAAKTEQAKQDNSLFFAIPWSQGTICFLVAATIKIIPCKKYVKLTYKKTETLSEMCEQL----TEDSDRNSENVDFVEALMFNKEKGCIMLGEFSD-GPDTHDEVVNPIGRWYKKWFYTHVEDLINKK-----HESIEYIPLRDYYHRHSKSIFWELRDIVPFGNNVLFRYLMAWMCPPKIAFLKATTPNVLRKLYDRSHVLQDMLVPLDKLEECIDLFHKEVEIYPMWLCP---FYLKSQPGLMK-------LRNATHKMYVDVGAYGVTS----KDGYHHERTTRRLESFVRSVNGFQMTYADIYMTRAEYAEMFDRTLYDWKRASCKCIDAFPDIYDKI 519

HSP 2 Score: 86.2705 bits (212), Expect = 9.061e-85
Identity = 50/129 (38.76%), Postives = 79/129 (61.24%), Query Frame = 2 
Query:  143 EFLEEH-RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTF-FKKEECQKIEIP-LFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            EF+  H R + VV F LP SF+F  + +FR  +V   +    +H+ +V+ IQ+Q+++WN+  ++++  L N+RP WL++S  F   KE   KI    LF IL+ +  K TV  EP VT+GQ++ YL+ R
Sbjct:   19 EFIMFHFRWVFVVPFLLPLSFLFNTVFDFRNRIVHAVNSAPNAHVRKVKHIQEQLKEWNDNGRKSK--LVNARPGWLTMSFRFPLYKENATKIATDKLFDILDLDVEKMTVKAEPGVTMGQLSQYLISR 145
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Match: A0A1W2W6U8 (delta(24)-sterol reductase-like OS=Ciona intestinalis OX=7719 GN=LOC100187505 PE=4 SV=1)

HSP 1 Score: 532.717 bits (1371), Expect = 0.000e+0
Identity = 251/402 (62.44%), Postives = 310/402 (77.11%), Query Frame = 1 
Query:  526 VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFV 1731
             LA TLEI DATCGGLAM VGMTT+SHKVGL+QE+VVSY +V +DGS IHVE+DNEH +L+ CLPWSHG+LGFLV+LELKII    YI L+Y PV G +NYC++MR+ SGA        PD+LEATVFS DE+VI+ G+F       +   +N++++WYKPWFYKHVE+FL+         G+E IP++ YL RHNR+IFWV+EA+IPF N+P+FR   GW+CPPKPAFLKFTTTPG+RA TF +QVFQDIVLPMT LE+SI+++E LF+ YPILIYPC+++    + G LR P+  QM   ++YGMFYDLGVYGVP  +K K++YD  KAMRSME FIR  GGYSFLYADIFM KEEF EMFDL+ YE+   KY A  AFPHLYDKVKPE++V EV + + 
Sbjct:  143 ALAVTLEIGDATCGGLAMAVGMTTYSHKVGLYQEAVVSYDVVTADGSLIHVERDNEHEDLFSCLPWSHGTLGFLVALELKIIKVKPYIHLQYIPVKGKKNYCDKMRLLSGALDKLA-TTPDYLEATVFSKDEAVIMVGNFSYADKPGEMGKVNNVARWYKPWFYKHVETFLRTG------GGDEYIPLQQYLLRHNRAIFWVVEAMIPFGNHPIFRALLGWLCPPKPAFLKFTTTPGVRAMTFTRQVFQDIVLPMTVLEKSIDIAEDLFDTYPILIYPCRIYDHGVNSGQLRPPREDQMCPGANYGMFYDLGVYGVPGKVKRKERYDSVKAMRSMESFIRQHGGYSFLYADIFMTKEEFHEMFDLTLYEQCRVKYGAVGAFPHLYDKVKPEINVFEVGRTWA 537

HSP 2 Score: 147.517 bits (371), Expect = 0.000e+0
Identity = 66/126 (52.38%), Postives = 92/126 (73.02%), Query Frame = 2 
Query:  143 EFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            ++LE++RGLVVV+FCLPASF+F + + FR ++++        H +RVR IQ  VRKWN++P ENR+ +C SRPNWLSLSTTFF+K++C +I + LF IL  +E    V VEP V+V  +TDYL+ R
Sbjct:   15 KWLEDNRGLVVVLFCLPASFIFDVCLRFRNWVIRYLFSAPHQHNERVRTIQAAVRKWNDLPTENRRPMCTSRPNWLSLSTTFFQKKDCHQITVSLFDILNLDEENMIVKVEPMVSVRDVTDYLITR 140
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Match: F6ZXA7 (FAD-binding PCMH-type domain-containing protein OS=Ciona intestinalis OX=7719 PE=4 SV=2)

HSP 1 Score: 532.717 bits (1371), Expect = 0.000e+0
Identity = 251/402 (62.44%), Postives = 310/402 (77.11%), Query Frame = 1 
Query:  526 VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFV 1731
             LA TLEI DATCGGLAM VGMTT+SHKVGL+QE+VVSY +V +DGS IHVE+DNEH +L+ CLPWSHG+LGFLV+LELKII    YI L+Y PV G +NYC++MR+ SGA        PD+LEATVFS DE+VI+ G+F       +   +N++++WYKPWFYKHVE+FL+         G+E IP++ YL RHNR+IFWV+EA+IPF N+P+FR   GW+CPPKPAFLKFTTTPG+RA TF +QVFQDIVLPMT LE+SI+++E LF+ YPILIYPC+++    + G LR P+  QM   ++YGMFYDLGVYGVP  +K K++YD  KAMRSME FIR  GGYSFLYADIFM KEEF EMFDL+ YE+   KY A  AFPHLYDKVKPE++V EV + + 
Sbjct:  127 ALAVTLEIGDATCGGLAMAVGMTTYSHKVGLYQEAVVSYDVVTADGSLIHVERDNEHEDLFSCLPWSHGTLGFLVALELKIIKVKPYIHLQYIPVKGKKNYCDKMRLLSGALDKLA-TTPDYLEATVFSKDEAVIMVGNFSYADKPGEMGKVNNVARWYKPWFYKHVETFLRTG------GGDEYIPLQQYLLRHNRAIFWVVEAMIPFGNHPIFRALLGWLCPPKPAFLKFTTTPGVRAMTFTRQVFQDIVLPMTVLEKSIDIAEDLFDTYPILIYPCRIYDHGVNSGQLRPPREDQMCPGANYGMFYDLGVYGVPGKVKRKERYDSVKAMRSMESFIRQHGGYSFLYADIFMTKEEFHEMFDLTLYEQCRVKYGAVGAFPHLYDKVKPEINVFEVGRTWA 521

HSP 2 Score: 147.132 bits (370), Expect = 0.000e+0
Identity = 66/124 (53.23%), Postives = 90/124 (72.58%), Query Frame = 2 
Query:  149 LEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            LE++RGLVVV+FCLPASF+F + + FR ++++        H +RVR IQ  VRKWN++P ENR+ +C SRPNWLSLSTTFF+K++C +I + LF IL  +E    V VEP V+V  +TDYL+ R
Sbjct:    1 LEDNRGLVVVLFCLPASFIFDVCLRFRNWVIRYLFSAPHQHNERVRTIQAAVRKWNDLPTENRRPMCTSRPNWLSLSTTFFQKKDCHQITVSLFDILNLDEENMIVKVEPMVSVRDVTDYLITR 124
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Match: A0A267FXT9 (FAD-binding PCMH-type domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017234g4 PE=4 SV=1)

HSP 1 Score: 532.717 bits (1371), Expect = 0.000e+0
Identity = 246/406 (60.59%), Postives = 316/406 (77.83%), Query Frame = 1 
Query:  526 VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPS-RGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQK-YDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFVLA 1737
             LA TLEISDATCGGLA+GVGMTT+SH+VGL+QE++VSY +VL DGS +    DNEH +LY+CLPWSHG+LGFLV+LEL+II    ++ +RY PV G + YC++MR  SGA    +  +PD+LEATVF  D +VI+ G+F ++ T  K   +N +++WYKPWFYKHVE+FL K         +E IP++DYL RHNR+IFWVLE++IPF N+P+FRLF GW+CPPKPAFLKFTTTPGIRA TF KQVFQDIVLPMT LEESI+LSEKLF+ YP+LIYPC+++   PS RG LR+PK+ QM   ++YGMFYDLGVYG P  ++ K+  Y+P ++MR+ME FIR  GGYSFLYADIF+ +EEF EMFDL  Y +  +KYHA+ AFP LY+KV+PE+DV+++   +  A
Sbjct:  145 TLAVTLEISDATCGGLALGVGMTTYSHRVGLYQETIVSYDVVLGDGSLVRATADNEHKDLYYCLPWSHGTLGFLVALELQIIPVKQFVHMRYIPVRGQKQYCDRMRELSGALDK-DAKLPDYLEATVFDRDSAVIMVGNFAKVDTPEKAAKVNHVTRWYKPWFYKHVETFLTKG------ESDEYIPLRDYLLRHNRAIFWVLESMIPFGNHPVFRLFLGWLCPPKPAFLKFTTTPGIRAMTFSKQVFQDIVLPMTVLEESIDLSEKLFDTYPVLIYPCRIYDHGPSNRGQLRSPKSDQMCPGANYGMFYDLGVYGTPGPVRRKRGYYNPVESMRAMEAFIRKVGGYSFLYADIFLTEEEFNEMFDLEAYNRARKKYHAEGAFPRLYEKVRPEVDVVKIGNEYAQA 543

HSP 2 Score: 128.642 bits (322), Expect = 9.880e-28
Identity = 60/125 (48.00%), Postives = 84/125 (67.20%), Query Frame = 2 
Query:  146 FLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            +LE++RGLV+V+FCLPASF+F   ++   +  +        H  RVR+IQ++V  WN+    +R+ +C SRPNWLSLSTTFFKK EC +I + L+ IL+ +  +  V VEP VTVG IT YL+ R
Sbjct:   18 WLEDNRGLVIVLFCLPASFIFDTGLSLYKWFQRTLLSAPERHDARVRQIQRRVGDWNKQDAPSRRPMCTSRPNWLSLSTTFFKKSECHRIPVDLYDILQLDTERMVVRVEPMVTVGDITRYLIPR 142
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Match: A0A0P5YK95 (Delta(24)-sterol reductase OS=Daphnia magna OX=35525 GN=APZ42_031794 PE=4 SV=1)

HSP 1 Score: 524.242 bits (1349), Expect = 0.000e+0
Identity = 239/411 (58.15%), Postives = 313/411 (76.16%), Query Frame = 1 
Query:  499 NRLFT*KKVVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFV 1731
             R    K   LA TLEI+DAT GGLA GVGMTT+SHKVGL+QE++ +Y +VL DGS + V KDNE+S+L+HCLPWSHG+LGFLV+LE++II    Y+++ Y P+ G + YC+++R  SGA    +   PDF+EAT+FS +E+VI+ G F  +K   +   IN +++WYKPWFYKHVESFL KP        +E IP+++YL RHNR+IFWV+E++IPF NNP+FR  FGW+ PPKPAFLKFTTTPGIRA TF KQVFQDIVLP+  LE+ I++SE++F+ YPIL+YPC+++   P  G LR P+  QM   +++GMF DLGVYGVP  +K KQ++D   AMR MEKF RD GGY FLYADIFM+++EF EMFDL  YE++  KYHA++AFPHLYDKVKPE+DV++V K ++
Sbjct:  131 TRYLIPKGYTLAVTLEIADATLGGLAFGVGMTTYSHKVGLYQETIAAYEVVLGDGSLVRVTKDNEYSDLFHCLPWSHGTLGFLVALEVQIIPVKPYVRMEYIPIKGQKEYCDKIRELSGAMDK-DKQTPDFVEATIFSKNEAVIMVGHFANVKNAQEEAQINHVARWYKPWFYKHVESFLNKP------PSQEFIPLREYLLRHNRAIFWVVESMIPFGNNPVFRFLFGWLLPPKPAFLKFTTTPGIRAMTFTKQVFQDIVLPINVLEKQIDVSEEIFDAYPILVYPCRIYDHGPHTGQLRPPRPDQMCPGTNWGMFNDLGVYGVPGPVKRKQRFDAVAAMRKMEKFTRDVGGYPFLYADIFMDRKEFEEMFDLEAYERVRTKYHANDAFPHLYDKVKPEIDVIKVGKEYM 534

HSP 2 Score: 142.51 bits (358), Expect = 0.000e+0
Identity = 66/125 (52.80%), Postives = 88/125 (70.40%), Query Frame = 2 
Query:  146 FLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
             +E++RGL+V++FCLPASFVF L +  R +  +        H +RVR+IQ +VRK N++P   +K +C +RPNWLSLSTTFF+K+ C KI IPL+ ILE NE   TV VEP VTVG IT YL+ +
Sbjct:   13 LMEDNRGLIVLLFCLPASFVFDLALQLRNWFYRTVLSAPQRHDERVRQIQSKVRKCNDLPDSEKKKMCTARPNWLSLSTTFFRKDLCHKIPIPLYDILELNEEAMTVRVEPMVTVGDITRYLIPK 137
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Match: A0A267H929 (FAD-binding PCMH-type domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017234g1 PE=4 SV=1)

HSP 1 Score: 530.406 bits (1365), Expect = 2.025e-180
Identity = 245/406 (60.34%), Postives = 315/406 (77.59%), Query Frame = 1 
Query:  526 VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPS-RGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQK-YDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFVLA 1737
             LA TLEISDATCGGLA+GVGMTT+SH+VGL+QE++VSY +VL DGS +    DNEH +LY+CLPWSHG+LGFLV+LEL+II    ++ +RY PV G + YC++MR  SGA    +  +PD+LEATVF  D +VI+ G+F ++ T  K   +N +++WYKPWFYKHVE+FL K         +E IP++DYL RHNR+IFWVLE++IPF N+P+FRLF GW+CPPKPAFLKFTTTPGIRA TF KQVFQDIVLPMT LEESI+LSEKLF+ YP+LIYPC+++   PS RG LR+PK+ QM   ++YGMFYDLGVYG P  ++ K+  Y+P ++MR+ME FIR  GGYSFLYADIF+ +EEF EMFDL  Y +  + YHA+ AFP LY+KV+PE+DV+++   +  A
Sbjct:  145 TLAVTLEISDATCGGLALGVGMTTYSHRVGLYQETIVSYDVVLGDGSLVRATADNEHKDLYYCLPWSHGTLGFLVALELQIIPVKQFVHMRYIPVRGQKQYCDRMRELSGALDK-DAKLPDYLEATVFDRDSAVIMVGNFAKVDTPEKAAKVNHVTRWYKPWFYKHVETFLTKG------ESDEYIPLRDYLLRHNRAIFWVLESMIPFGNHPVFRLFLGWLCPPKPAFLKFTTTPGIRAMTFSKQVFQDIVLPMTVLEESIDLSEKLFDTYPVLIYPCRIYDHGPSNRGQLRSPKSDQMCPGANYGMFYDLGVYGTPGPVRRKRGYYNPVESMRAMEAFIRKVGGYSFLYADIFLTEEEFNEMFDLEAYNRARKMYHAEGAFPRLYEKVRPEVDVVKIGNEYAQA 543

HSP 2 Score: 127.872 bits (320), Expect = 1.435e-27
Identity = 60/125 (48.00%), Postives = 83/125 (66.40%), Query Frame = 2 
Query:  146 FLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKR 520
            +LE++RGLV+V+FCLPASF+F   ++   +  +        H  RVR+IQ++V  WN+    +R+ +C SRPNWLSLSTTFFKK EC +I + L+ IL  +  +  V VEP VTVG IT YL+ R
Sbjct:   18 WLEDNRGLVIVLFCLPASFIFDTGLSLYKWFQRTLLSAPERHDARVRQIQRRVGDWNKQDAASRRPMCTSRPNWLSLSTTFFKKSECHRIPVDLYDILHLDTERMVVRVEPMVTVGDITRYLIPR 142
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Cavefish
Match: dhcr24 (24-dehydrocholesterol reductase [Source:ZFIN;Acc:ZDB-GENE-041212-73])

HSP 1 Score: 278.485 bits (711), Expect = 1.734e-86
Identity = 154/382 (40.31%), Postives = 228/382 (59.69%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SH  GLFQ   V+Y LVL+DGS +    + E+S+L++ +PWS G+LGFLV+ E++II A  ++KLRY+ V G++N C   + FS  ES+  +N   F+E   +S DE+VI+ G   +     K   IN I  +YKPWF+KHVE +LK     D     E IP++ Y  RH RSIFW L+ IIPF NNPLFR  FGWM PPK + LK T    IR       V QD+++PM  ++ ++    +  ++YP+ + P    F  PS+  + +PK       ++  ++ D+G YG P+     + ++   + R +EKF+RD  G+  LYAD++M + EF EMFD + Y K+ ++   + AFP +YDK+
Sbjct:  145 ELDDLTVGGLVMGTGIESSSHIYGLFQHICVAYELVLADGSLVRC-TEKENSDLFYSVPWSCGTLGFLVAAEIRIIPARKWVKLRYKAVRGLDNIC---KTFS-EESANKEN--QFVEGLQYSLDEAVIMTGTMTDDAEPDK---INRIGYYYKPWFFKHVEQYLK-----DDRVAVEYIPLRHYYHRHTRSIFWELQDIIPFGNNPLFRYVFGWMVPPKISLLKLTQGETIRRLYEQHHVVQDMLVPMKNIKMALTRFHQDIHVYPLWLCP----FILPSQPGMVHPK------GNEDELYVDIGAYGEPKV----KHFEAQASTRQLEKFVRDVHGFQMLYADVYMERPEFWEMFDGTLYHKLRKELGCEEAFPEVYDKI 497

HSP 2 Score: 62.003 bits (149), Expect = 1.734e-86
Identity = 36/117 (30.77%), Postives = 57/117 (48.72%), Query Frame = 2 
Query:  161 RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            R + V +F LP S +F +    R +++         H  RVR IQ+QVR+W +  +  +K +C  RP WL+             I I +  IL+ +  ++ V VEP   +GQ+T  L
Sbjct:   31 RWIFVCLFLLPLSVIFDVYYYVRAWIIFKMCSAPKLHDQRVRDIQRQVREWKK--EGGKKHMCTGRPGWLT------------NIMINMMDILQVDTKRQVVRVEPLANMGQVTALL 133
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Sea Lamprey
Match: dhcr24 (24-dehydrocholesterol reductase [Source:ZFIN;Acc:ZDB-GENE-041212-73])

HSP 1 Score: 288.115 bits (736), Expect = 9.803e-95
Identity = 153/382 (40.05%), Postives = 227/382 (59.42%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ T SH  GLFQ   VS+ LVL+DGS +    + E+S+L++ +PWS+G+LGFLV+ E++I+ A  Y+KLRY PV G++  C+  +           +   F+E  ++  +E+VI+ G+  +     K   IN+I  ++KPWF+KHVE FL K     G    E IP++ Y  RH RSIFW L+ IIPF N+P+FR+  GWM PPK A LK T    +R       V QD+++PM AL++S+       N+YP+ + P    F+ PS   + +PK+ Q        M+ D+G YG P+     + Y      R +E+F+RDQ G+  LYAD +M++EEF  MFD + Y+K+ ++Y  + AFP +YDK+
Sbjct:  158 ELDDLTVGGLIMGTGIETSSHIYGLFQHICVSFELVLADGSLVRCS-ETENSDLFYAVPWSYGTLGFLVAAEVRIVPARHYVKLRYTPVRGLDAICSTFQ-----HECTRPDPATFVEGLMYGRNEAVIMTGELTDTAEPDK---INNIGYYWKPWFFKHVEGFLHK----SGPPCVEYIPLRHYHHRHTRSIFWELQDIIPFGNHPVFRMLLGWMVPPKIALLKLTQGEVVRKLYEQHHVVQDMLVPMHALQKSLTCFHDEINLYPLWLCP----FRLPSVPGMVHPKSDQEE------MYVDIGAYGEPKM----KGYTAGTTTRRLEQFVRDQHGFQMLYADSYMSREEFWNMFDPTLYQKMRKQYGCEGAFPEVYDKI 512

HSP 2 Score: 77.411 bits (189), Expect = 9.803e-95
Identity = 47/122 (38.52%), Postives = 64/122 (52.46%), Query Frame = 2 
Query:  149 LEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            L +HR L V +F LP S +F      R +LV         H  RVR IQKQVR+W    +  +  +C  RP WL++S    K ++  K I I L  ILE +  ++ V VEP V +GQ+T  L
Sbjct:   27 LVQHRWLFVCLFLLPLSVLFDAYYFIRAWLVFRMCSAPKQHDQRVRDIQKQVRQWRA--EGGQTYMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKRQIVRVEPLVNMGQVTSLL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Nematostella
Match: EDO36241 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ62])

HSP 1 Score: 265.388 bits (677), Expect = 3.639e-86
Identity = 151/388 (38.92%), Postives = 221/388 (56.96%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHV-EKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVD-----SDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SHK GLFQ   V + LVL+DG+ +H  +K+NEH  L++ +PWSHG+LGFLV+ E+ II A  Y++L Y PV    +   ++      ES   +N  +F+EA  +S  E+V++ G F +     K   +N I  ++KPWF+KHV+S+LK         G E IP++DY  RH RSIFW L+ IIPF NN ++R  FGW+ PPK + LK T    +R       V QD+++P+  L  S+    + F +YP+ I  C ++       L R P  +   VD     SD  M+ D+G YG P+     + +   + MR +E F++   G+  LYAD +M +EEF  MFD   Y+K+ ++     AFP +YDKV
Sbjct:  164 ELDDLTVGGLIMGCGIESSSHKFGLFQHICVGFDLVLADGTLVHASKKENEH--LFYSIPWSHGTLGFLVAAEIIIIPAKKYVRLSYNPV----HSKKELETSFTRESMSKEN--EFVEALAYSEIEAVVMTGTFEDEAEPDK---LNPIGYFWKPWFFKHVQSYLKSG------PGVEYIPLRDYYHRHTRSIFWELQDIIPFGNNVIWRYLFGWVMPPKISLLKLTQGETLRRLYEQHHVVQDMLVPIETLGNSLSCFHENFELYPLWI--CPMY-------LPRTPGLVHAPVDKRRPHSDGRMYVDIGAYGTPKV----KNFVARENMRRVEAFVKSVDGFQMLYADSYMTREEFRAMFDHELYDKLREEMQCKEAFPEIYDKV 521

HSP 2 Score: 72.4034 bits (176), Expect = 3.639e-86
Identity = 48/133 (36.09%), Postives = 73/133 (54.89%), Query Frame = 2 
Query:  161 RGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRK-LLCNSRPNWLSLSTTF--FKKEECQKIEIPLFQILEFN----EMKRTVTVEPYVTVGQITDYLLKRKLFWLV 538
            R + V +F LP S ++   +  R +L   +      H +RV+K+Q+QV+KWN   K+ RK  +C +RP W+++S     +KK  C  I++ L  ILE N    E    V VEP VT+GQ+T  L+   L W +
Sbjct:   33 RWIFVCLFLLPVSVLYESFLFVRNWLAFKYYSDPERHKERVQKVQEQVQKWN---KDGRKQPMCTARPGWMTVSPRVGKYKKTHCN-IDVNLMDILEINCAAGESTGVVRVEPMVTMGQLTHALV--PLGWTI 159
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Medaka
Match: dhcr24 (24-dehydrocholesterol reductase [Source:NCBI gene;Acc:101172722])

HSP 1 Score: 288.886 bits (738), Expect = 6.206e-91
Identity = 154/382 (40.31%), Postives = 228/382 (59.69%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SH  GLFQ   V+Y LVL+DGS +   ++ E+ +L+H +PWS G+LGFLV+ E+KI+ A  ++KLR  PV G+EN C   R F+ A S+  +    F+E   +S D +V++ G   +   H +   IN I   +KPWF+KHVE +LK     +G +G E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    IR     + V QD+++PM  L+ +I    +   +YP+ + P   F   P RG++ +PK  Q        ++ D+G YG P+     + ++   + R +EKF+RD  G+  LYAD++M++EEF EMFD   Y ++ ++    +AFP +Y K+
Sbjct:  158 ELDDLTVGGLVMGTGIESSSHIYGLFQHICVAYELVLADGSLVRCSEE-ENVDLFHAVPWSCGTLGFLVAAEIKIVPAKPWVKLRLEPVRGLENIC---RRFAEASSNKQNT---FVEGLQYSLDSAVVMTGTMTD---HAEPDKINRIGLHFKPWFFKHVEGYLK-----EGRTGVEYIPLRQYYHRHTRSIFWELQDIIPFGNNPVFRWLFGWMVPPKISLLKLTQGETIRRLYEQRHVVQDMLVPMKHLQAAITRFHQDIKVYPLWLCP---FLLLPGRGMV-HPKGDQEE------LYVDIGAYGEPKV----KHFEAKASTRQLEKFVRDCHGFQMLYADVYMDREEFWEMFDGQLYHRLREELGCKDAFPEVYSKI 510

HSP 2 Score: 66.6254 bits (161), Expect = 6.206e-91
Identity = 39/122 (31.97%), Postives = 62/122 (50.82%), Query Frame = 2 
Query:  149 LEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMKRTVTVEPYVTVGQITDYL 511
            L   R + V  F LP S +F +    R +++         H  RVR +Q+QVR+W +   ++   +C  RP WL++S    K ++  K I I +  ILE +  ++ V VEP   +GQ+T  L
Sbjct:   27 LVHQRWIFVCAFLLPLSVIFDVYYYVRAWIIFKMCSAPKLHDQRVRDVQRQVREWRKDGAKSH--MCTGRPGWLTVSLRVGKYKKTHKNILINMMDILEVDTKRQVVKVEPLANMGQVTALL 146
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Medaka
Match: dhcr24 (24-dehydrocholesterol reductase [Source:NCBI gene;Acc:101172722])

HSP 1 Score: 288.5 bits (737), Expect = 5.246e-90
Identity = 154/382 (40.31%), Postives = 228/382 (59.69%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKV 1689
            E+ D T GGL MG G+ + SH  GLFQ   V+Y LVL+DGS +   ++ E+ +L+H +PWS G+LGFLV+ E+KI+ A  ++KLR  PV G+EN C   R F+ A S+  +    F+E   +S D +V++ G   +   H +   IN I   +KPWF+KHVE +LK     +G +G E IP++ Y  RH RSIFW L+ IIPF NNP+FR  FGWM PPK + LK T    IR     + V QD+++PM  L+ +I    +   +YP+ + P   F   P RG++ +PK  Q        ++ D+G YG P+     + ++   + R +EKF+RD  G+  LYAD++M++EEF EMFD   Y ++ ++    +AFP +Y K+
Sbjct:  174 ELDDLTVGGLVMGTGIESSSHIYGLFQHICVAYELVLADGSLVRCSEE-ENVDLFHAVPWSCGTLGFLVAAEIKIVPAKPWVKLRLEPVRGLENIC---RRFAEASSNKQNT---FVEGLQYSLDSAVVMTGTMTD---HAEPDKINRIGLHFKPWFFKHVEGYLK-----EGRTGVEYIPLRQYYHRHTRSIFWELQDIIPFGNNPVFRWLFGWMVPPKISLLKLTQGETIRRLYEQRHVVQDMLVPMKHLQAAITRFHQDIKVYPLWLCP---FLLLPGRGMV-HPKGDQEE------LYVDIGAYGEPKV----KHFEAKASTRQLEKFVRDCHGFQMLYADVYMDREEFWEMFDGQLYHRLREELGCKDAFPEVYSKI 526

HSP 2 Score: 56.6102 bits (135), Expect = 5.407e-8
Identity = 39/138 (28.26%), Postives = 62/138 (44.93%), Query Frame = 2 
Query:  149 LEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQK-IEIPLFQILEFNEMK----------------RTVTVEPYVTVGQITDYL 511
            L   R + V  F LP S +F +    R +++         H  RVR +Q+QVR+W +   ++   +C  RP WL++S    K ++  K I I +  ILE +  +                + V VEP   +GQ+T  L
Sbjct:   27 LVHQRWIFVCAFLLPLSVIFDVYYYVRAWIIFKMCSAPKLHDQRVRDVQRQVREWRKDGAKSH--MCTGRPGWLTVSLRVGKYKKTHKNILINMMDILEVDTKRQHTVNKRGRLTNKFNTKVVKVEPLANMGQVTALL 162
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Planmine SMEST
Match: SMESG000022021.1 (SMESG000022021.1)

HSP 1 Score: 835.869 bits (2158), Expect = 0.000e+0
Identity = 398/401 (99.25%), Postives = 400/401 (99.75%), Query Frame = 1 
Query:  517 KKVVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEVS 1719
            +K VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLE+S
Sbjct:  134 RKFVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPELDVLEIS 534

HSP 2 Score: 262.307 bits (669), Expect = 0.000e+0
Identity = 128/132 (96.97%), Postives = 129/132 (97.73%), Query Frame = 2 
Query:  128 KVVSCEFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK 523
            K+   EFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK
Sbjct:    4 KLSLVEFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK 135
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Planmine SMEST
Match: SMESG000022021.1 (SMESG000022021.1)

HSP 1 Score: 327.405 bits (838), Expect = 1.230e-164
Identity = 157/159 (98.74%), Postives = 158/159 (99.37%), Query Frame = 1 
Query:  517 KKVVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDIS 993
            +K VLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDIS
Sbjct:  134 RKFVLACTLEISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDIS 292

HSP 2 Score: 263.848 bits (673), Expect = 1.230e-164
Identity = 127/127 (100.00%), Postives = 127/127 (100.00%), Query Frame = 2 
Query:  143 EFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK 523
            EFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK
Sbjct:    9 EFLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRK 135

HSP 3 Score: 31.187 bits (69), Expect = 1.230e-164
Identity = 13/14 (92.86%), Postives = 14/14 (100.00%), Query Frame = 2 
Query:  995 NGISHGSINMSNPF 1036
            +GISHGSINMSNPF
Sbjct:  295 DGISHGSINMSNPF 308
[Close]
BLAST of FAD-binding PCMH-type domain-containing protein vs. Planmine SMEST
Match: SMESG000076611.1 (SMESG000076611.1)

HSP 1 Score: 273.863 bits (699), Expect = 6.947e-88
Identity = 155/392 (39.54%), Postives = 226/392 (57.65%), Query Frame = 1 
Query:  544 EISDATCGGLAMGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWSHGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYNDNIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHVESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRLFFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEKLFNIYPILIYPCKLF----FQNPS---RGLLRNPKTIQMTVDSDYGMFYDLGVYGVPRAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSNYEKICQKYHADNAFPHLYDKVKPE 1698
            E+ D T GGL MG G+ T SHK GLFQ   +   LVL DG  I      E+ +L++   WSHG++GFLVS ++KII A  YIK+ Y P   M++   +   F        DN  +F+EA VFS D  V++ G+ +  K   K   IN I  +YKPWF+KHVE  +K+ I+       E IPI+DY  RH+RSIFW ++ IIPF NN +FR  FGW  PPK + LK T    I+    V  V QD+++P+  +++S+    K  +I+P+ + P +LF       P+     ++      +  V+  Y M+ D+GVYGVP+       YD     R++E F+R  GG+  LYAD +M ++EF +MF+ S Y+K+ +KYH++ AFP +YDK+  +
Sbjct:  152 ELDDLTVGGLIMGTGIETSSHKHGLFQHICIELKLVLHDGELITCSP-TENEDLFYAAFWSHGTIGFLVSADIKIIRAKSYIKVDYYPCHSMDDLVEK---FQSETMKPFDN--EFVEALVFSPDSGVVMTGN-MSCKPKNKKQ-INSIGSFYKPWFFKHVEFIMKQEISV----FTEFIPIRDYYHRHSRSIFWEIQDIIPFGNNSIFRHLFGWAVPPKISLLKLTQGEVIKKMYEVSHVLQDMLVPIRYIQDSLLFFNKEVSIFPLWLCPFRLFKLPGLVQPNFDKSEIIHQISFQKNDVNEKYVMYVDIGVYGVPKV----STYDAFNTTRNLEAFVRRVGGFQMLYADTYMTRKEFRDMFNHSLYDKVREKYHSEAAFPEIYDKISKD 527

HSP 2 Score: 70.8626 bits (172), Expect = 6.947e-88
Identity = 49/143 (34.27%), Postives = 75/143 (52.45%), Query Frame = 2 
Query:  146 FLEEHRGLVVVMFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPKENRKLLCNSRPNWLSLSTTFFK-KEECQKIEIPLFQILEFNEMKRTVTVEPYVTVGQITDYLLKRKLFWLVR*KYPMPLVED 571
            F+  +R + V++F LP S ++ +L N R  ++   +     H  RV+ IQKQ+R W     + +  LC +RP W ++S    K K    KI I L  +L  NE K+ V VEP VT+ Q++  LL   L W +     MP ++D
Sbjct:   20 FIVNYRWIFVLIFLLPLSVLYNILSNIRDRIIFYLNSAPKFHETRVKNIQKQIRTWWMSGSKTK--LCTARPGWKTMSFRVGKYKSNSHKIYINLIDVLFVNEEKKFVRVEPLVTMKQLSATLL--PLGWTIP---VMPELDD 155
The following BLAST results are available for this feature:
BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DHCR241.798e-9641.8824-dehydrocholesterol reductase [Source:HGNC Symbo... [more]
DHCR241.798e-9641.8824-dehydrocholesterol reductase [Source:HGNC Symbo... [more]
DHCR246.134e-9440.6124-dehydrocholesterol reductase [Source:HGNC Symbo... [more]
DHCR241.443e-1641.6724-dehydrocholesterol reductase [Source:HGNC Symbo... [more]
DHCR248.822e-1649.0924-dehydrocholesterol reductase [Source:HGNC Symbo... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Y7A5A.11.489e-16452.45pep chromosome:WBcel235:X:15767437:15771509:-1 gen... [more]
Y7A5A.11.489e-16452.45pep chromosome:WBcel235:X:15767437:15771493:-1 gen... [more]
F52H2.68.717e-8635.90Diminuto-like protein [Source:UniProtKB/Swiss-Pro... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dhcr243.624e-9039.5324-dehydrocholesterol reductase [Source:ZFIN;Acc:Z... [more]
dhcr243.965e-5342.2124-dehydrocholesterol reductase [Source:ZFIN;Acc:Z... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dhcr243.414e-9140.1024-dehydrocholesterol reductase [Source:NCBI gene;... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Dhcr246.000e-9541.1024-dehydrocholesterol reductase [Source:MGI Symbol... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q60HC5|DHC24_MACFA6.138e-9641.88Delta(24)-sterol reductase OS=Macaca fascicularis ... [more]
sp|Q15392|DHC24_HUMAN7.876e-9641.88Delta(24)-sterol reductase OS=Homo sapiens OX=9606... [more]
sp|Q8VCH6|DHC24_MOUSE3.629e-9441.10Delta(24)-sterol reductase OS=Mus musculus OX=1009... [more]
sp|Q5BQE6|DHC24_RAT8.260e-9441.36Delta(24)-sterol reductase OS=Rattus norvegicus OX... [more]
sp|O17397|DIML_CAEEL9.061e-8535.90Diminuto-like protein OS=Caenorhabditis elegans OX... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1W2W6U80.000e+062.44delta(24)-sterol reductase-like OS=Ciona intestina... [more]
F6ZXA70.000e+062.44FAD-binding PCMH-type domain-containing protein OS... [more]
A0A267FXT99.880e-2860.59FAD-binding PCMH-type domain-containing protein OS... [more]
A0A0P5YK950.000e+058.15Delta(24)-sterol reductase OS=Daphnia magna OX=355... [more]
A0A267H9292.025e-18060.34FAD-binding PCMH-type domain-containing protein OS... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dhcr241.734e-8640.3124-dehydrocholesterol reductase [Source:ZFIN;Acc:Z... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dhcr249.803e-9540.0524-dehydrocholesterol reductase [Source:ZFIN;Acc:Z... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO362413.639e-8638.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dhcr246.206e-9140.3124-dehydrocholesterol reductase [Source:NCBI gene;... [more]
dhcr245.246e-9040.3124-dehydrocholesterol reductase [Source:NCBI gene;... [more]
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BLAST of FAD-binding PCMH-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000022021.10.000e+099.25SMESG000022021.1[more]
SMESG000022021.11.230e-16498.74SMESG000022021.1[more]
SMESG000076611.16.947e-8839.54SMESG000076611.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033367 ID=SMED30033367|Name=FAD-binding PCMH-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1781bp
ATAAAATCAAAAAGTTCGTATGTAACTTACGTACATTTGGTTTGACTTTG
ACATAGGCTGTTATGTCATTTATTTATTATATATTGTTAATCTGATTTTT
ATTCATTATTTTTCAAAAGATGTCTTTAAAGTTGTCTCTTGTGAATTTTT
GGAAGAACACCGAGGACTCGTTGTTGTGATGTTTTGTTTACCTGCGTCGT
TTGTGTTCGGCCTCCTCATTAATTTCAGGACTTATTTGGTGCAGTTATTT
TCCAGGTTTTCTGGCTCACATTTAGATAGAGTTCGAAAAATTCAAAAACA
AGTTCGAAAGTGGAACGAAATACCTAAAGAAAATAGAAAATTACTCTGTA
ACTCAAGACCTAATTGGTTGTCACTGTCGACAACCTTTTTCAAAAAAGAA
GAATGTCAAAAAATTGAAATCCCTCTTTTTCAAATATTAGAATTTAATGA
AATGAAAAGAACAGTAACAGTTGAACCATACGTGACAGTTGGACAAATAA
CAGATTATTTACTTAAAAGAAAGTTGTTTTGGCTTGTACGTTAGAAATAT
CCGATGCCACTTGTGGAGGACTGGCAATGGGAGTTGGGATGACTACCCAC
TCTCACAAAGTCGGATTGTTTCAAGAAAGTGTTGTATCATATGGATTAGT
TTTATCCGATGGATCATTTATACACGTTGAAAAGGATAATGAACACTCAA
ATCTATATCATTGCCTACCATGGTCTCATGGATCTTTGGGATTTTTAGTC
TCCCTAGAACTAAAGATCATTTCTGCAACTGATTACATTAAATTAAGATA
CCGACCGGTAGTTGGAATGGAGAATTATTGTAATCAAATGAGAATATTTT
CTGGTGCCGAAAGTTCATACAATGACAACATTCCTGATTTCTTAGAAGCT
ACCGTTTTCAGTCATGATGAGTCCGTGATAATATTTGGTGATTTTATTGA
AATCAAAACCCATACAAAAAATTACTACATAAATGACATTTCCAAATGGT
ATAAGCCATGGTTCTATAAACATGTCGAATCCTTTCTAAAGAAACCAATA
AATGCTGATGGATTTTCAGGCGAAGAAATTATTCCTATTAAAGATTATTT
ATTCAGACATAATCGTTCAATATTCTGGGTCCTGGAAGCGATCATTCCAT
TTTGCAATAACCCATTATTTCGATTGTTCTTTGGTTGGATGTGTCCACCT
AAACCGGCATTTTTAAAATTTACGACTACTCCAGGAATTCGTGCTTTTAC
TTTTGTCAAACAAGTTTTCCAAGATATAGTTCTACCCATGACTGCTCTAG
AAGAGTCAATAGAACTATCCGAGAAACTTTTCAATATCTATCCAATTTTG
ATTTATCCATGCAAATTATTTTTTCAAAATCCATCCCGAGGACTTCTGAG
AAATCCCAAAACCATCCAGATGACAGTAGATTCGGATTATGGTATGTTTT
ACGATTTAGGAGTTTACGGCGTCCCTCGAGCTATAAAGCTTAAGCAAAAA
TATGATCCGTCTAAAGCAATGAGATCAATGGAAAAATTTATTCGAGATCA
AGGAGGCTATTCTTTTTTATATGCTGACATATTTATGAATAAAGAAGAAT
TCTGTGAAATGTTTGATTTGTCCAATTATGAGAAGATTTGTCAAAAGTAT
CACGCGGATAATGCCTTTCCACATTTATATGATAAAGTAAAACCGGAATT
AGATGTTTTAGAAGTTAGTAAGAACTTTGTTCTTGCCGGAAACCATTGAA
AACAAATTTTGTTGTGAAGATTAATTAAATA
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protein sequence of SMED30033367-orf-1

>SMED30033367-orf-1 ID=SMED30033367-orf-1|Name=SMED30033367-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=391bp
MGVGMTTHSHKVGLFQESVVSYGLVLSDGSFIHVEKDNEHSNLYHCLPWS
HGSLGFLVSLELKIISATDYIKLRYRPVVGMENYCNQMRIFSGAESSYND
NIPDFLEATVFSHDESVIIFGDFIEIKTHTKNYYINDISKWYKPWFYKHV
ESFLKKPINADGFSGEEIIPIKDYLFRHNRSIFWVLEAIIPFCNNPLFRL
FFGWMCPPKPAFLKFTTTPGIRAFTFVKQVFQDIVLPMTALEESIELSEK
LFNIYPILIYPCKLFFQNPSRGLLRNPKTIQMTVDSDYGMFYDLGVYGVP
RAIKLKQKYDPSKAMRSMEKFIRDQGGYSFLYADIFMNKEEFCEMFDLSN
YEKICQKYHADNAFPHLYDKVKPELDVLEVSKNFVLAGNH*
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protein sequence of SMED30033367-orf-2

>SMED30033367-orf-2 ID=SMED30033367-orf-2|Name=SMED30033367-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=122bp
MFCLPASFVFGLLINFRTYLVQLFSRFSGSHLDRVRKIQKQVRKWNEIPK
ENRKLLCNSRPNWLSLSTTFFKKEECQKIEIPLFQILEFNEMKRTVTVEP
YVTVGQITDYLLKRKLFWLVR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0071949FAD binding
GO:0003824catalytic activity
GO:0016614oxidoreductase activity, acting on CH-OH group of donors
GO:0050660flavin adenine dinucleotide binding
GO:0016491oxidoreductase activity
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: INTERPRO
TermDefinition
IPR016169FAD-bd_PCMH_sub2
IPR016166FAD-bd_PCMH
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane