ER lumen protein-retaining receptor

Overview
NameER lumen protein-retaining receptor
Smed IDSMED30033329
Length (bp)1204
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ER lumen protein-retaining receptor (SMED30033329) t-SNE clustered cells

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30033329) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ER lumen protein-retaining receptor (SMED30033329) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30033329) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033329

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30033329SMESG000064394.1 dd_Smed_v4_1592_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30033329SMESG000064394.1 dd_Smed_v4_1592_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30033329SMESG000064394.1 dd_Smed_v4_1592_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30033329SMESG000064394.1 dd_Smed_v4_1592_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033329SMESG000064394.1 Contig43775uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033329SMESG000064394.1 Contig43775newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305])

HSP 1 Score: 335.495 bits (859), Expect = 6.469e-115
Identity = 160/212 (75.47%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MKV++L  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 306.99 bits (785), Expect = 1.056e-103
Identity = 145/211 (68.72%), Postives = 180/211 (85.31%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            MN+FR+ GD+SHL+A+I+LL KIW+++ C GISGKSQI+FALVFT RYLDLFT+F+SIYN+VMKV+FLL  Y+TVY+++ KF+ T DS +DTFR EFL+ P   L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI RY  ENF+D IAVVSG VQTI YCDFFYLY+TKVLKG+K+ LP
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 302.753 bits (774), Expect = 3.870e-102
Identity = 152/212 (71.70%), Postives = 190/212 (89.62%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV+L++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 290.041 bits (741), Expect = 5.821e-97
Identity = 138/201 (68.66%), Postives = 171/201 (85.07%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITK 710
            MN+FR+ GD+SHL+A+I+LL KIW+++ C GISGKSQI+FALVFT RYLDLFT+F+SIYN+VMKV+FLL  Y+TVY+++ KF+ T DS +DTFR EFL+ P   L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI RY  ENF+D IAVVSG VQTI YCDFFYLY+TK
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTK 201          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 228.794 bits (582), Expect = 6.402e-74
Identity = 107/150 (71.33%), Postives = 131/150 (87.33%), Query Frame = 3
Query:  294 MKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MKV+++  ++ TV+L++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.1 (ER lumen protein-retaining receptor [Source:UniProtKB/Swiss-Prot;Acc:P48583])

HSP 1 Score: 305.064 bits (780), Expect = 2.374e-103
Identity = 135/207 (65.22%), Postives = 177/207 (85.51%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK 728
            MN+FR   D++H +AI++LLLKIWK+RSC GISG+SQ++FALVF  RYLDLFT+F S YN+ MK+ +L+ ++ TVYLMW KFKAT D N+D+FR EFL+ P  ILA+++NH+F F+E+ WTFSIY+EAVAI+PQLF++S+TG AE+IT+HYLFALGSYR LYILNW+YRYY E+FFD I+VV+G VQT+LY DFFYLYIT+V++  +
Sbjct:    1 MNLFRFTADVAHAIAIVVLLLKIWKSRSCEGISGRSQLLFALVFVTRYLDLFTNFFSFYNTAMKIFYLVASFGTVYLMWAKFKATYDRNNDSFRIEFLVIPSMILALLINHEFIFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYILNWVYRYYTESFFDPISVVAGIVQTVLYADFFYLYITRVIQSNR 207          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 294.664 bits (753), Expect = 2.482e-99
Identity = 147/212 (69.34%), Postives = 180/212 (84.91%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK-IRLP 740
            MNIFR++ DMSHL+AIIILLLKIWK+RSCSGIS +SQI+FALVFTARYLDLF++++S+YN+ MK+ FL  TY TVYLM+FKF++T     DTFR E LI P AILA+++NHDF+  E+ WTFSIY+EAVAILPQLFL+  TG AE IT+HYLFALGSYRALYI NWIYRYY E++FD I VV+G VQT+LY DFFYLY+T+V++ RK + LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 294.664 bits (753), Expect = 2.482e-99
Identity = 147/212 (69.34%), Postives = 180/212 (84.91%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK-IRLP 740
            MNIFR++ DMSHL+AIIILLLKIWK+RSCSGIS +SQI+FALVFTARYLDLF++++S+YN+ MK+ FL  TY TVYLM+FKF++T     DTFR E LI P AILA+++NHDF+  E+ WTFSIY+EAVAILPQLFL+  TG AE IT+HYLFALGSYRALYI NWIYRYY E++FD I VV+G VQT+LY DFFYLY+T+V++ RK + LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080021)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080023)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080022)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2a (KDEL endoplasmic reticulum protein retention receptor 2a [Source:NCBI gene;Acc:373129])

HSP 1 Score: 328.561 bits (841), Expect = 1.933e-112
Identity = 156/212 (73.58%), Postives = 185/212 (87.26%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KF+AT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2b (KDEL endoplasmic reticulum protein retention receptor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-4189])

HSP 1 Score: 327.791 bits (839), Expect = 4.146e-112
Identity = 155/212 (73.11%), Postives = 185/212 (87.26%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+V+ILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKVIYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVSILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 288.115 bits (736), Expect = 2.050e-96
Identity = 138/212 (65.09%), Postives = 178/212 (83.96%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MNIFRL+GD+ HL+AIIIL LKIW+++SC+GISGKSQ++FALVFT RYLDLFTS++S YN++MKV++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 288.115 bits (736), Expect = 2.050e-96
Identity = 138/212 (65.09%), Postives = 178/212 (83.96%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MNIFRL+GD+ HL+AIIIL LKIW+++SC+GISGKSQ++FALVFT RYLDLFTS++S YN++MKV++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: CABZ01075611.1 (pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDARG00000104519.2 transcript:ENSDART00000165169.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01075611.1)

HSP 1 Score: 176.792 bits (447), Expect = 3.588e-53
Identity = 85/138 (61.59%), Postives = 111/138 (80.43%), Query Frame = 3
Query:  297 KVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITK 710
            +V++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+
Sbjct:   38 QVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTR 175          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:NCBI gene;Acc:395012])

HSP 1 Score: 328.561 bits (841), Expect = 3.315e-112
Identity = 155/212 (73.11%), Postives = 186/212 (87.74%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL+GD+SHL AIIILLLKIWK+RSC+GISGKSQ++FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   L+++VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+RY  E FFDLIA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNVFRLSGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTSMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRYSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:496456])

HSP 1 Score: 327.791 bits (839), Expect = 5.240e-112
Identity = 153/212 (72.17%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR  GD+SHL AI+ILLLKIWK+RSC+GISGKSQ++FA+VFT RYLDLFT+F+S+YN+ MK++++  +Y T+++++ KFKAT D NHDTFR EFLI P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YRALY+ NWI+RY  E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: stx1a (syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753])

HSP 1 Score: 276.944 bits (707), Expect = 1.609e-91
Identity = 140/206 (67.96%), Postives = 176/206 (85.44%), Query Frame = 3
Query:  123 LAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            ++GD+SHL+AIIILLLK+WK++SC+GISGKSQ++FALVFT RYLDLFT F+S YN+VMK++FL+  Y+TVYL++ KF+   DS +DTFR EFL+ P   L+ + N++F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAESIT+HYLF LG YR LY+ NWI+RY+ E F+D IAVVSG VQTI Y DFFYLYITKVLKG+K+ LP
Sbjct:   35 ISGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLP 240          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr2 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 [Source:MGI Symbol;Acc:MGI:1914163])

HSP 1 Score: 332.798 bits (852), Expect = 4.342e-114
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr3 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:MGI Symbol;Acc:MGI:2145953])

HSP 1 Score: 305.064 bits (780), Expect = 4.719e-103
Identity = 140/212 (66.04%), Postives = 183/212 (86.32%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR+ GD+SHL+A+I+LL+KIW+++SC+GISGKSQI+FALVFT RYLDLF++F+SIYN+VMKV+FLL  Y+TVY++++KF+ T D  +DTFR EFL+ P   L+ +VN+ ++ +E+ WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YR LY+ NWI RY  ENF+D I+VVSG VQTI YCDFFYLY+TKVLKG+K+ LP 
Sbjct:    1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 302.368 bits (773), Expect = 4.481e-102
Identity = 151/212 (71.23%), Postives = 190/212 (89.62%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 228.024 bits (580), Expect = 8.327e-74
Identity = 106/150 (70.67%), Postives = 131/150 (87.33%), Query Frame = 3
Query:  294 MKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 179.104 bits (453), Expect = 6.235e-55
Identity = 93/137 (67.88%), Postives = 122/137 (89.05%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFL 518
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF+
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFM 137          
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|O76767|ERD2_DROME (ER lumen protein-retaining receptor OS=Drosophila melanogaster OX=7227 GN=KdelR PE=2 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 3.043e-116
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|P33947|ERD22_HUMAN (ER lumen protein-retaining receptor 2 OS=Homo sapiens OX=9606 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 335.495 bits (859), Expect = 3.107e-114
Identity = 160/212 (75.47%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MKV++L  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5ZKX9|ERD22_CHICK (ER lumen protein-retaining receptor 2 OS=Gallus gallus OX=9031 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 333.183 bits (853), Expect = 2.415e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFLI P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+RYY E FFDLIAVV+G VQT+LYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5U305|ERD22_RAT (ER lumen protein-retaining receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdelr2 PE=2 SV=1)

HSP 1 Score: 332.798 bits (852), Expect = 3.037e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q9CQM2|ERD22_MOUSE (ER lumen protein-retaining receptor 2 OS=Mus musculus OX=10090 GN=Kdelr2 PE=1 SV=1)

HSP 1 Score: 332.798 bits (852), Expect = 3.037e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A077Z6A3 (ER lumen protein-retaining receptor OS=Trichuris trichiura OX=36087 GN=TTRE_0000396401 PE=3 SV=1)

HSP 1 Score: 352.829 bits (904), Expect = 1.503e-118
Identity = 164/212 (77.36%), Postives = 195/212 (91.98%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA+VFTARYLDLFT   S YN+VMKV+FL+ TY+TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF ++EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQTILY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAVVFTARYLDLFTHIYSYYNTVMKVVFLVCTYVTVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFHYVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTILYADFFYLYVTRVLKGRKIQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A1V9WYN6 (ER lumen protein-retaining receptor OS=Tropilaelaps mercedesae OX=418985 GN=BIW11_14307 PE=3 SV=1)

HSP 1 Score: 352.443 bits (903), Expect = 1.790e-118
Identity = 156/212 (73.58%), Postives = 195/212 (91.98%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL AIIILLLKIWKTRSC+GISG+SQ++F++V+TARYLDL TSF+S+YN+VMKV+FL+ +Y T+YLMW KFKAT D NHDTFR EFL+ PCA+LA+++NH+F+ +E+ WTFSIY+EAVAILPQLF++SKTGEAE+ITSHYLFALGSYRALYI NWIYRYY E+F+D IA+V+G VQT+LYCDFFYLY+TKV+KG+ ++LPA
Sbjct:    1 MNLFRLVGDLSHLFAIIILLLKIWKTRSCAGISGRSQLLFSVVYTARYLDLVTSFISVYNTVMKVIFLVASYGTLYLMWVKFKATYDRNHDTFRVEFLLAPCAVLALLINHEFTIMELLWTFSIYLEAVAILPQLFMVSKTGEAETITSHYLFALGSYRALYIFNWIYRYYAEHFYDFIAIVAGVVQTVLYCDFFYLYVTKVIKGKALKLPA 212          
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A085N272 (ER lumen protein-retaining receptor OS=Trichuris suis OX=68888 GN=M513_01637 PE=3 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 3.761e-118
Identity = 164/212 (77.36%), Postives = 194/212 (91.51%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA VFTARYLDLFT   S YN+VMKV+FL+ TY+TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF ++EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQTILY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAAVFTARYLDLFTHIYSYYNTVMKVVFLVCTYVTVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFHYVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTILYADFFYLYVTRVLKGRKIQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A067QLS7 (ER lumen protein-retaining receptor OS=Zootermopsis nevadensis OX=136037 GN=L798_15651 PE=3 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 1.913e-117
Identity = 161/212 (75.94%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL+AI++LLLKIWKTRSC+GISGKSQI+FALV+T RYLDL TSFVS YN+VMKV+F+  +Y T+YLM+ KFKAT D NHDTFR EFLI P   LA+++NH+F+ LE+ WTFSIY+E+VAILPQLFL+SKTGEAESITSHYLFALG+YRALY+LNWIYRYY EN +DLIA+V+G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRLLGDLSHLLAIVVLLLKIWKTRSCAGISGKSQILFALVYTTRYLDLLTSFVSAYNTVMKVIFVGASYATIYLMYLKFKATYDQNHDTFRIEFLIIPAVALALLINHEFTVLEVLWTFSIYLESVAILPQLFLVSKTGEAESITSHYLFALGTYRALYLLNWIYRYYFENHYDLIAIVAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A5S6QP95 (ER lumen protein-retaining receptor OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 4.631e-117
Identity = 163/212 (76.89%), Postives = 193/212 (91.04%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA VFTARYLDLFT   S YN+VMKV+FL+ TY TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF+ +EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQT+LY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAAVFTARYLDLFTHVYSYYNTVMKVIFLVCTYATVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFNHVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTVLYADFFYLYVTRVLKGRKIQLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: kdelr2a (ER lumen protein-retaining receptor 2-like [Source:NCBI gene;Acc:103040303])

HSP 1 Score: 336.265 bits (861), Expect = 1.914e-115
Identity = 161/212 (75.94%), Postives = 187/212 (88.21%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFLI P   LA +VNHDFS LEI WTFSIY+E+VAILPQLFLISKTGEAE+IT+HYLF+LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLAGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRIEFLIVPVGGLAFLVNHDFSPLEIMWTFSIYLESVAILPQLFLISKTGEAETITTHYLFSLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:103025946])

HSP 1 Score: 330.102 bits (845), Expect = 4.099e-113
Identity = 157/212 (74.06%), Postives = 186/212 (87.74%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLINWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR3 (ER lumen protein-retaining receptor 3 [Source:NCBI gene;Acc:103035602])

HSP 1 Score: 298.516 bits (763), Expect = 1.092e-100
Identity = 142/212 (66.98%), Postives = 181/212 (85.38%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+SHLVAII+L LKIW+++SC+GISGKSQ++FA+VFT RYLDLFT F+SIYN+VMKV+FL+  Y TVYL++ +F+ + DS +D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSHLVAIILLFLKIWRSKSCAGISGKSQVLFAVVFTTRYLDLFTGFISIYNTVMKVVFLVLAYATVYLIYLRFRNSYDSENDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITTHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000042346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000042346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 139.813 bits (351), Expect = 3.771e-39
Identity = 99/227 (43.61%), Postives = 125/227 (55.07%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTAR-YLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLE-------------IFWTFSIYMEAVAILPQLFLISKTGEAESI-TSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+S    + + L         +GISGKSQ+   L  +    L   T F+SIYN+VMKV  L G  I +  ++      N  ++D+       G C  +A       SFLE             I WTFSIY+E+V           TGEAES    HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSAFSCLCVCLCVC------AGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGCLPGVGIPLQFIYSTCAFRN--SYDSGMHFISGGSCCSVA-----GLSFLEKLTPSTPTGGNTPILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 203          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000040094.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000040094.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 7.126e-36
Identity = 90/214 (42.06%), Postives = 113/214 (52.80%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTAR-YLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESI-TSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+S     + L +       C+GISGKSQ+   L  +    L   T F+SIYN+VMKV     T+               ++  T                        +I WTFSIY+E+V           TGEAES    HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSAFSLCVCLCV-------CAGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGKHKHTHKHHTQHTHTHTPHTHTHTTTHPHS--------------------QILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 176          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 310.842 bits (795), Expect = 3.300e-106
Identity = 155/212 (73.11%), Postives = 192/212 (90.57%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRLAGD+SHL+AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL T+++S+YN+ MKV+++  +Y TV++++ KFKAT DSNHDTFR EFL+ P A+L+++VNHD+S +EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNVFRLAGDLSHLLAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTNYISLYNTTMKVIYIGCSYATVWMIYSKFKATYDSNHDTFRVEFLVLPVALLSLVVNHDYSVVEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYFAEGFFDLIAIVAGLVQTILYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 310.457 bits (794), Expect = 5.387e-106
Identity = 157/212 (74.06%), Postives = 190/212 (89.62%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL+AIIILL+KIWKTRSC+GISGKSQI+FALVFT RYLDLFT+F+SIYN+ MKV+++   Y T+++++ KFKAT D N+DTFR EFL+ P   L+++VNHDFS LEI WTFSIY+E+VAILPQLFL+SKTGEAE+ITSHYLFALG YRALY+LNWI+RYY E FFDLIA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNVFRLTGDLSHLLAIIILLIKIWKTRSCAGISGKSQILFALVFTTRYLDLFTTFISIYNTSMKVVYMACAYATLWMIYHKFKATYDGNNDTFRVEFLVVPIGGLSVLVNHDFSLLEILWTFSIYLESVAILPQLFLVSKTGEAETITSHYLFALGLYRALYLLNWIWRYYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Match: ERD2 (HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136])

HSP 1 Score: 206.453 bits (524), Expect = 1.754e-65
Identity = 108/218 (49.54%), Postives = 155/218 (71.10%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFT-SFVSIYNSVMKVLFLLGT-YITVYLMWFKFKATNDSN----HDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGEN-FFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            MN FR+ GD+SHL +I+IL+  I  TR   GIS K+Q ++ALVF  RYLDL T  +VS+YN++MK+ F++ T YI V L   K   T   N    HDTF+ + L+   A++++  +H F+FLE+ W+FS+++E+VAILPQL+++SK G+  S+T HY+FA+G YRALYI NWI+RY  E+   D IA  +G +QT+LY DFFY+Y TKV++G+  +LP
Sbjct:    1 MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP 218          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Match: EDO48388 (ER lumen protein retaining receptor [Source:UniProtKB/TrEMBL;Acc:A7RJJ4])

HSP 1 Score: 342.428 bits (877), Expect = 2.106e-118
Identity = 160/212 (75.47%), Postives = 190/212 (89.62%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHLVAII+LL KIWKTRSC+G+SGKSQ+MFALVF+ RYLDLFTSFVS+YNSVMKV+++   + T+YLM+ KFKAT DSNHDTFR EFL+ P A LA +VNH+F+ +E+ WTFSIY+E+VAILPQLF+ISKTGEAESITSHYLFALG+YRALYI NW+YRYY E F+D IA+V+GCVQT LYCDFFYLYITKVLKG+ ++LPA
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr2b (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101160362])

HSP 1 Score: 330.487 bits (846), Expect = 2.577e-113
Identity = 157/212 (74.06%), Postives = 185/212 (87.26%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+GISGKSQ++FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYVKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: KDELR2 (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101157057])

HSP 1 Score: 331.643 bits (849), Expect = 9.511e-113
Identity = 155/212 (73.11%), Postives = 187/212 (88.21%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL TSF+S+YNS MKV+++  +Y TVYL++ KF+AT D NHD+FR EFL+ P   LA+++NHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQT+LYCDFFYLY+TKVLKG+K+ LPA
Sbjct:   60 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNSSMKVIYIGCSYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 271          
BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:101155114])

HSP 1 Score: 298.516 bits (763), Expect = 1.223e-100
Identity = 144/212 (67.92%), Postives = 181/212 (85.38%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRLAGD+SHLVAIIILLLKIW++RSC+GISGKSQ++FA+VFT RYLDLFT F+S YN++MKV+FL  +Y TVYL++ +FK T +S +D+FR EFL+ P   L+ + N+ F+ LEI WTFSI++E+VAI+PQLF+I+KTGEAESIT+HYLF LG YRALYI NW++RY+ E FFD IAVVSG VQTI Y DFFYLY+TKVL+GR K+ LP
Sbjct:    1 MNVFRLAGDVSHLVAIIILLLKIWRSRSCAGISGKSQVLFAIVFTTRYLDLFTIFISPYNTIMKVVFLALSYATVYLIYVRFKNTFNSENDSFRLEFLLVPVIGLSFLENYAFTPLEILWTFSIFLESVAIMPQLFMITKTGEAESITTHYLFFLGLYRALYIANWVWRYHTEGFFDQIAVVSGVVQTIFYIDFFYLYVTKVLRGRGKMTLP 212          
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 430.639 bits (1106), Expect = 6.624e-153
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 212          
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 353.599 bits (906), Expect = 4.229e-123
Identity = 174/174 (100.00%), Postives = 174/174 (100.00%), Query Frame = 3
Query:  222 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 174          
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000073757.1 (SMESG000073757.1)

HSP 1 Score: 297.36 bits (760), Expect = 2.002e-100
Identity = 137/203 (67.49%), Postives = 174/203 (85.71%), Query Frame = 3
Query:  135 MSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MSHL+AII+LL KIWK+RSC+G+SGKSQIMFA+VF  RYLDLF  ++S+YN +MK  F++ + +TVY ++FKFKAT D NHD+FR EF++ P   LA+++NH FSF+EI WT+SIY+E++AILPQL+LISKTGEAE+ITSHYLFALG YRA YILNW YR++ E+F+DLIA+ SG +QTILYCDFFYLY+TKVLKG+   LPA
Sbjct:    1 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 203          
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000053522.1 (SMESG000053522.1)

HSP 1 Score: 289.656 bits (740), Expect = 2.300e-97
Identity = 136/212 (64.15%), Postives = 171/212 (80.66%), Query Frame = 3
Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+G+SGK+QI+F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    1 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 212          
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 280.796 bits (717), Expect = 5.526e-95
Identity = 135/135 (100.00%), Postives = 135/135 (100.00%), Query Frame = 3
Query:  339 MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 135          
The following BLAST results are available for this feature:
BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KDELR26.469e-11575.47KDEL endoplasmic reticulum protein retention recep... [more]
KDELR31.056e-10368.72KDEL endoplasmic reticulum protein retention recep... [more]
KDELR13.870e-10271.70KDEL endoplasmic reticulum protein retention recep... [more]
KDELR35.821e-9768.66KDEL endoplasmic reticulum protein retention recep... [more]
KDELR16.402e-7471.33KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
erd-2.12.374e-10365.22ER lumen protein-retaining receptor [Source:UniPr... [more]
erd-2.22.482e-9969.34Putative ER lumen protein-retaining receptor C28H8... [more]
erd-2.22.482e-9969.34Putative ER lumen protein-retaining receptor C28H8... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
KdelR3.035e-11773.58gene:FBgn0267330 transcript:FBtr0080021[more]
KdelR3.035e-11773.58gene:FBgn0267330 transcript:FBtr0080023[more]
KdelR3.035e-11773.58gene:FBgn0267330 transcript:FBtr0080022[more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdelr2a1.933e-11273.58KDEL endoplasmic reticulum protein retention recep... [more]
kdelr2b4.146e-11273.11KDEL endoplasmic reticulum protein retention recep... [more]
kdelr32.050e-9665.09KDEL endoplasmic reticulum protein retention recep... [more]
kdelr32.050e-9665.09KDEL endoplasmic reticulum protein retention recep... [more]
CABZ01075611.13.588e-5361.59pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDA... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kdelr13.315e-11273.11KDEL endoplasmic reticulum protein retention recep... [more]
kdelr25.240e-11272.17KDEL endoplasmic reticulum protein retention recep... [more]
stx1a1.609e-9167.96syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753][more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kdelr24.342e-11474.53KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr34.719e-10366.04KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr14.481e-10271.23KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr18.327e-7470.67KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr16.235e-5567.88KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O76767|ERD2_DROME3.043e-11673.58ER lumen protein-retaining receptor OS=Drosophila ... [more]
sp|P33947|ERD22_HUMAN3.107e-11475.47ER lumen protein-retaining receptor 2 OS=Homo sapi... [more]
sp|Q5ZKX9|ERD22_CHICK2.415e-11374.53ER lumen protein-retaining receptor 2 OS=Gallus ga... [more]
sp|Q5U305|ERD22_RAT3.037e-11374.53ER lumen protein-retaining receptor 2 OS=Rattus no... [more]
sp|Q9CQM2|ERD22_MOUSE3.037e-11374.53ER lumen protein-retaining receptor 2 OS=Mus muscu... [more]
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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A077Z6A31.503e-11877.36ER lumen protein-retaining receptor OS=Trichuris t... [more]
A0A1V9WYN61.790e-11873.58ER lumen protein-retaining receptor OS=Tropilaelap... [more]
A0A085N2723.761e-11877.36ER lumen protein-retaining receptor OS=Trichuris s... [more]
A0A067QLS71.913e-11775.94ER lumen protein-retaining receptor OS=Zootermopsi... [more]
A0A5S6QP954.631e-11776.89ER lumen protein-retaining receptor OS=Trichuris m... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdelr2a1.914e-11575.94ER lumen protein-retaining receptor 2-like [Source... [more]
KDELR24.099e-11374.06KDEL endoplasmic reticulum protein retention recep... [more]
KDELR31.092e-10066.98ER lumen protein-retaining receptor 3 [Source:NCBI... [more]
ENSAMXT00000042346.13.771e-3943.61pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000040094.17.126e-3642.06pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
KDELR13.300e-10673.11KDEL endoplasmic reticulum protein retention recep... [more]
KDELR15.387e-10674.06KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ERD21.754e-6549.54HDEL receptor; an integral membrane protein that b... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO483882.106e-11875.47ER lumen protein retaining receptor [Source:UniPr... [more]
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BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kdelr2b2.577e-11374.06ER lumen protein-retaining receptor 2 [Source:NCBI... [more]
KDELR29.511e-11373.11ER lumen protein-retaining receptor 2 [Source:NCBI... [more]
kdelr31.223e-10067.92KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000064394.16.624e-153100.00SMESG000064394.1[more]
SMESG000064394.14.229e-123100.00SMESG000064394.1[more]
SMESG000073757.12.002e-10067.49SMESG000073757.1[more]
SMESG000053522.12.300e-9764.15SMESG000053522.1[more]
SMESG000064394.15.526e-95100.00SMESG000064394.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033329 ID=SMED30033329|Name=ER lumen protein-retaining receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1204bp
TTTAACTTAAATCTTTAAATGACCTTAAAACTTCTTTAAATTATTCAGCG
AATTTATTGACACGTTTGTTTGTGTAAACATATTTGAAAATTAATTAATA
GGACAAGATGAATATATTTAGATTAGCGGGTGATATGTCCCATTTAGTGG
CCATAATAATTTTGCTTCTTAAAATTTGGAAAACTAGATCTTGTTCAGGA
ATATCTGGAAAAAGTCAAATTATGTTTGCTTTGGTCTTTACAGCTAGATA
TTTAGACTTGTTTACGTCATTTGTATCCATATATAATTCTGTTATGAAAG
TTTTGTTCCTATTAGGAACATATATTACTGTATATTTAATGTGGTTCAAA
TTTAAAGCCACAAATGACAGTAATCATGATACATTTCGTTTTGAGTTTCT
TATTGGTCCATGTGCAATATTAGCAATTATTGTCAATCATGATTTCTCTT
TTCTTGAGATATTTTGGACCTTTTCTATTTACATGGAAGCAGTTGCTATT
TTACCCCAATTATTTTTAATTAGTAAAACTGGCGAAGCTGAATCGATAAC
TTCACATTACCTTTTTGCACTCGGTTCATATAGGGCGTTGTACATTTTGA
ATTGGATATATCGATATTACGGGGAGAATTTCTTTGATTTGATAGCCGTT
GTTTCTGGGTGTGTTCAAACGATTCTCTACTGTGATTTCTTTTATCTCTA
TATTACGAAAGTGCTGAAAGGACGCAAGATCAGGTTGCCGGCTTGAATGG
TGCGCGATCGGTCGATCAATGAGTTCCTGTTCTGTTGATGTTGCTGTTCA
TTAGCTGTGTAGCTTTTTTGAAATTGAAAAATGGTTTTTTTGTCGAACTT
GTAATAAATCTTGTTTCGTATTTTGATTTTCTTGTTGTGTTTGAATTTTG
CAATGTGACAATTTTCAAATATTATAAATTTATTCCATATGTGAGATGAT
AATGATGATAATAATGATTGTCAGAGTTTTCAGTTTCTTTTGTATGTTTA
TTTGATCATATTGATTTAAAGAAATGTGAATTATTGATTTTATATAAGTG
CTTTCTTCTGGTCTTTATAAATACAAAGGTGTTTGTGTTGTTATTGTTTG
CTGATCAGTCCATTAATGAAAATTCATTGAGCATTTCACTTGCTTGTAGG
GCATTTCGTATTCGCTTGCACACCTTTGGTATTTAAAGATAACCGGTATG
GGCA
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protein sequence of SMED30033329-orf-1

>SMED30033329-orf-1 ID=SMED30033329-orf-1|Name=SMED30033329-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=213bp
MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLD
LFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIG
PCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSH
YLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYIT
KVLKGRKIRLPA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000133ER_ret_rcpt
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0030140trans-Golgi network transport vesicle
Vocabulary: biological process
TermDefinition
GO:0006621protein retention in ER lumen
GO:0006810transport
GO:0006890retrograde vesicle-mediated transport, Golgi to ER
GO:0015031protein transport
GO:0016192vesicle-mediated transport
GO:0019233sensory perception of pain
Vocabulary: molecular function
TermDefinition
GO:0046923ER retention sequence binding
GO:0005046KDEL sequence binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000133ER lumen protein retaining receptorPRINTSPR00660ERLUMENRcoord: 52..68
score: 55.88
coord: 120..140
score: 75.85
coord: 31..51
score: 74.49
coord: 156..174
score: 69.55
coord: 4..23
score: 67.14
coord: 184..199
score: 75.0
coord: 142..156
score: 73.81
IPR000133ER lumen protein retaining receptorPFAMPF00810ER_lumen_receptcoord: 28..169
e-value: 3.5E-54
score: 183.6
IPR000133ER lumen protein retaining receptorPANTHERPTHR10585ER LUMEN PROTEIN RETAINING RECEPTORcoord: 1..212
NoneNo IPR availablePANTHERPTHR10585:SF37ER LUMEN PROTEIN-RETAINING RECEPTOR 2coord: 1..212
NoneNo IPR availableTMHMMTMhelixcoord: 151..168
NoneNo IPR availableTMHMMTMhelixcoord: 178..200
NoneNo IPR availableTMHMMTMhelixcoord: 119..138
NoneNo IPR availableTMHMMTMhelixcoord: 92..109
NoneNo IPR availableTMHMMTMhelixcoord: 58..80