ER lumen protein-retaining receptor

Overview


Name	ER lumen protein-retaining receptor
Smed ID	SMED30033329
Length (bp)	1204

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ER lumen protein-retaining receptor (SMED30033329) t-SNE clustered cells

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30033329) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ER lumen protein-retaining receptor (SMED30033329) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30033329) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30033329

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
epidermis	SMED30033329	SMESG000064394.1	dd_Smed_v4_1592_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30033329	SMESG000064394.1	dd_Smed_v4_1592_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30033329	SMESG000064394.1	dd_Smed_v4_1592_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30033329	SMESG000064394.1	dd_Smed_v4_1592_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30033329	SMESG000064394.1	Contig43775	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30033329	SMESG000064394.1	Contig43775	uc_Smed_v2	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305])

HSP 1 Score: 335.495 bits (859), Expect = 6.469e-115
Identity = 160/212 (75.47%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MKV++L  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 306.99 bits (785), Expect = 1.056e-103
Identity = 145/211 (68.72%), Postives = 180/211 (85.31%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            MN+FR+ GD+SHL+A+I+LL KIW+++ C GISGKSQI+FALVFT RYLDLFT+F+SIYN+VMKV+FLL  Y+TVY+++ KF+ T DS +DTFR EFL+ P   L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI RY  ENF+D IAVVSG VQTI YCDFFYLY+TKVLKG+K+ LP
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLP 211

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 302.753 bits (774), Expect = 3.870e-102
Identity = 152/212 (71.70%), Postives = 190/212 (89.62%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV+L++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 290.041 bits (741), Expect = 5.821e-97
Identity = 138/201 (68.66%), Postives = 171/201 (85.07%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITK 710
            MN+FR+ GD+SHL+A+I+LL KIW+++ C GISGKSQI+FALVFT RYLDLFT+F+SIYN+VMKV+FLL  Y+TVY+++ KF+ T DS +DTFR EFL+ P   L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI RY  ENF+D IAVVSG VQTI YCDFFYLY+TK
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTK 201

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 228.794 bits (582), Expect = 6.402e-74
Identity = 107/150 (71.33%), Postives = 131/150 (87.33%), Query Frame = 3

Query:  294 MKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MKV+++  ++ TV+L++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.1 (ER lumen protein-retaining receptor [Source:UniProtKB/Swiss-Prot;Acc:P48583])

HSP 1 Score: 305.064 bits (780), Expect = 2.374e-103
Identity = 135/207 (65.22%), Postives = 177/207 (85.51%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK 728
            MN+FR   D++H +AI++LLLKIWK+RSC GISG+SQ++FALVF  RYLDLFT+F S YN+ MK+ +L+ ++ TVYLMW KFKAT D N+D+FR EFL+ P  ILA+++NH+F F+E+ WTFSIY+EAVAI+PQLF++S+TG AE+IT+HYLFALGSYR LYILNW+YRYY E+FFD I+VV+G VQT+LY DFFYLYIT+V++  +
Sbjct:    1 MNLFRFTADVAHAIAIVVLLLKIWKSRSCEGISGRSQLLFALVFVTRYLDLFTNFFSFYNTAMKIFYLVASFGTVYLMWAKFKATYDRNNDSFRIEFLVIPSMILALLINHEFIFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYILNWVYRYYTESFFDPISVVAGIVQTVLYADFFYLYITRVIQSNR 207

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 294.664 bits (753), Expect = 2.482e-99
Identity = 147/212 (69.34%), Postives = 180/212 (84.91%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK-IRLP 740
            MNIFR++ DMSHL+AIIILLLKIWK+RSCSGIS +SQI+FALVFTARYLDLF++++S+YN+ MK+ FL  TY TVYLM+FKF++T     DTFR E LI P AILA+++NHDF+  E+ WTFSIY+EAVAILPQLFL+  TG AE IT+HYLFALGSYRALYI NWIYRYY E++FD I VV+G VQT+LY DFFYLY+T+V++ RK + LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212

[Close]

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRK-IRLP 740
            MNIFR++ DMSHL+AIIILLLKIWK+RSCSGIS +SQI+FALVFTARYLDLF++++S+YN+ MK+ FL  TY TVYLM+FKF++T     DTFR E LI P AILA+++NHDF+  E+ WTFSIY+EAVAILPQLFL+  TG AE IT+HYLFALGSYRALYI NWIYRYY E++FD I VV+G VQT+LY DFFYLY+T+V++ RK + LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080021)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080023)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080022)

HSP 1 Score: 340.502 bits (872), Expect = 3.035e-117
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2a (KDEL endoplasmic reticulum protein retention receptor 2a [Source:NCBI gene;Acc:373129])

HSP 1 Score: 328.561 bits (841), Expect = 1.933e-112
Identity = 156/212 (73.58%), Postives = 185/212 (87.26%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KF+AT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2b (KDEL endoplasmic reticulum protein retention receptor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-4189])

HSP 1 Score: 327.791 bits (839), Expect = 4.146e-112
Identity = 155/212 (73.11%), Postives = 185/212 (87.26%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+V+ILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKVIYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVSILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 288.115 bits (736), Expect = 2.050e-96
Identity = 138/212 (65.09%), Postives = 178/212 (83.96%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MNIFRL+GD+ HL+AIIIL LKIW+++SC+GISGKSQ++FALVFT RYLDLFTS++S YN++MKV++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

[Close]

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MNIFRL+GD+ HL+AIIIL LKIW+++SC+GISGKSQ++FALVFT RYLDLFTS++S YN++MKV++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: CABZ01075611.1 (pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDARG00000104519.2 transcript:ENSDART00000165169.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01075611.1)

HSP 1 Score: 176.792 bits (447), Expect = 3.588e-53
Identity = 85/138 (61.59%), Postives = 111/138 (80.43%), Query Frame = 3

Query:  297 KVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITK 710
            +V++LL  Y TV L++F+F+ + DS  D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYL  LG YRALY+ NW++R++ E F+D IAVVSG VQTI YCDFFYLY T+
Sbjct:   38 QVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTR 175

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:NCBI gene;Acc:395012])

HSP 1 Score: 328.561 bits (841), Expect = 3.315e-112
Identity = 155/212 (73.11%), Postives = 186/212 (87.74%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL+GD+SHL AIIILLLKIWK+RSC+GISGKSQ++FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   L+++VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+RY  E FFDLIA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNVFRLSGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTSMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRYSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:496456])

HSP 1 Score: 327.791 bits (839), Expect = 5.240e-112
Identity = 153/212 (72.17%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR  GD+SHL AI+ILLLKIWK+RSC+GISGKSQ++FA+VFT RYLDLFT+F+S+YN+ MK++++  +Y T+++++ KFKAT D NHDTFR EFLI P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YRALY+ NWI+RY  E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: stx1a (syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753])

HSP 1 Score: 276.944 bits (707), Expect = 1.609e-91
Identity = 140/206 (67.96%), Postives = 176/206 (85.44%), Query Frame = 3

Query:  123 LAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            ++GD+SHL+AIIILLLK+WK++SC+GISGKSQ++FALVFT RYLDLFT F+S YN+VMK++FL+  Y+TVYL++ KF+   DS +DTFR EFL+ P   L+ + N++F+ LEI WTFSIY+E+VAILPQLF+ISKTGEAESIT+HYLF LG YR LY+ NWI+RY+ E F+D IAVVSG VQTI Y DFFYLYITKVLKG+K+ LP
Sbjct:   35 ISGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLP 240

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr2 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 [Source:MGI Symbol;Acc:MGI:1914163])

HSP 1 Score: 332.798 bits (852), Expect = 4.342e-114
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr3 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:MGI Symbol;Acc:MGI:2145953])

HSP 1 Score: 305.064 bits (780), Expect = 4.719e-103
Identity = 140/212 (66.04%), Postives = 183/212 (86.32%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR+ GD+SHL+A+I+LL+KIW+++SC+GISGKSQI+FALVFT RYLDLF++F+SIYN+VMKV+FLL  Y+TVY++++KF+ T D  +DTFR EFL+ P   L+ +VN+ ++ +E+ WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YR LY+ NWI RY  ENF+D I+VVSG VQTI YCDFFYLY+TKVLKG+K+ LP 
Sbjct:    1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 302.368 bits (773), Expect = 4.481e-102
Identity = 151/212 (71.23%), Postives = 190/212 (89.62%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 228.024 bits (580), Expect = 8.327e-74
Identity = 106/150 (70.67%), Postives = 131/150 (87.33%), Query Frame = 3

Query:  294 MKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQT+LYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 179.104 bits (453), Expect = 6.235e-55
Identity = 93/137 (67.88%), Postives = 122/137 (89.05%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFL 518
            MN+FR  GD+SHL+AII+LLLKIWK+RSC+GISGKSQ++FA+VFTARYLDLFT+++S+YN+ MKV+++  ++ TV++++ KFKAT D NHDTFR EFL+ P AILA +VNHDF+ LEI WTFSIY+E+VAILPQLF+
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFM 137

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|O76767|ERD2_DROME (ER lumen protein-retaining receptor OS=Drosophila melanogaster OX=7227 GN=KdelR PE=2 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 3.043e-116
Identity = 156/212 (73.58%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFR AGD+SH+ AIIILLLKIWKTRSC+GISGKSQI+FA+V+  RYLDLFT++VS+YNSVMKVLFL  +  TVYLM+ KFKAT D NHD+FR EFL+ PCA+L++++NH+F+ +E+ WTFSIY+E+VAILPQLFL+S+TGEAESITSHYLFALGSYRALY+LNW+YRY  E+ +DLIA+ +G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|P33947|ERD22_HUMAN (ER lumen protein-retaining receptor 2 OS=Homo sapiens OX=9606 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 335.495 bits (859), Expect = 3.107e-114
Identity = 160/212 (75.47%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MKV++L  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5ZKX9|ERD22_CHICK (ER lumen protein-retaining receptor 2 OS=Gallus gallus OX=9031 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 333.183 bits (853), Expect = 2.415e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFLI P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+RYY E FFDLIAVV+G VQT+LYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5U305|ERD22_RAT (ER lumen protein-retaining receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdelr2 PE=2 SV=1)

HSP 1 Score: 332.798 bits (852), Expect = 3.037e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q9CQM2|ERD22_MOUSE (ER lumen protein-retaining receptor 2 OS=Mus musculus OX=10090 GN=Kdelr2 PE=1 SV=1)

HSP 1 Score: 332.798 bits (852), Expect = 3.037e-113
Identity = 158/212 (74.53%), Postives = 188/212 (88.68%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AI+ILLLKIWKTRSC+GISGKSQ++FALVFT RYLDLFTSF+S+YN+ MK++++  +Y TVYL++ KFKAT D NHDTFR EFL+ P   L+ +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFDLIAVV+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A077Z6A3 (ER lumen protein-retaining receptor OS=Trichuris trichiura OX=36087 GN=TTRE_0000396401 PE=3 SV=1)

HSP 1 Score: 352.829 bits (904), Expect = 1.503e-118
Identity = 164/212 (77.36%), Postives = 195/212 (91.98%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA+VFTARYLDLFT   S YN+VMKV+FL+ TY+TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF ++EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQTILY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAVVFTARYLDLFTHIYSYYNTVMKVVFLVCTYVTVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFHYVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTILYADFFYLYVTRVLKGRKIQLPA 212

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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A1V9WYN6 (ER lumen protein-retaining receptor OS=Tropilaelaps mercedesae OX=418985 GN=BIW11_14307 PE=3 SV=1)

HSP 1 Score: 352.443 bits (903), Expect = 1.790e-118
Identity = 156/212 (73.58%), Postives = 195/212 (91.98%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL AIIILLLKIWKTRSC+GISG+SQ++F++V+TARYLDL TSF+S+YN+VMKV+FL+ +Y T+YLMW KFKAT D NHDTFR EFL+ PCA+LA+++NH+F+ +E+ WTFSIY+EAVAILPQLF++SKTGEAE+ITSHYLFALGSYRALYI NWIYRYY E+F+D IA+V+G VQT+LYCDFFYLY+TKV+KG+ ++LPA
Sbjct:    1 MNLFRLVGDLSHLFAIIILLLKIWKTRSCAGISGRSQLLFSVVYTARYLDLVTSFISVYNTVMKVIFLVASYGTLYLMWVKFKATYDRNHDTFRVEFLLAPCAVLALLINHEFTIMELLWTFSIYLEAVAILPQLFMVSKTGEAETITSHYLFALGSYRALYIFNWIYRYYAEHFYDFIAIVAGVVQTVLYCDFFYLYVTKVIKGKALKLPA 212

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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A085N272 (ER lumen protein-retaining receptor OS=Trichuris suis OX=68888 GN=M513_01637 PE=3 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 3.761e-118
Identity = 164/212 (77.36%), Postives = 194/212 (91.51%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA VFTARYLDLFT   S YN+VMKV+FL+ TY+TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF ++EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQTILY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAAVFTARYLDLFTHIYSYYNTVMKVVFLVCTYVTVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFHYVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTILYADFFYLYVTRVLKGRKIQLPA 212

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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A067QLS7 (ER lumen protein-retaining receptor OS=Zootermopsis nevadensis OX=136037 GN=L798_15651 PE=3 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 1.913e-117
Identity = 161/212 (75.94%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL+AI++LLLKIWKTRSC+GISGKSQI+FALV+T RYLDL TSFVS YN+VMKV+F+  +Y T+YLM+ KFKAT D NHDTFR EFLI P   LA+++NH+F+ LE+ WTFSIY+E+VAILPQLFL+SKTGEAESITSHYLFALG+YRALY+LNWIYRYY EN +DLIA+V+G VQT+LYCDFFYLYITKVLKG+K++LPA
Sbjct:    1 MNIFRLLGDLSHLLAIVVLLLKIWKTRSCAGISGKSQILFALVYTTRYLDLLTSFVSAYNTVMKVIFVGASYATIYLMYLKFKATYDQNHDTFRIEFLIIPAVALALLINHEFTVLEVLWTFSIYLESVAILPQLFLVSKTGEAESITSHYLFALGTYRALYLLNWIYRYYFENHYDLIAIVAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

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BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A5S6QP95 (ER lumen protein-retaining receptor OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 4.631e-117
Identity = 163/212 (76.89%), Postives = 193/212 (91.04%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL+AII+LL+KIWK+RSC+GISG+SQ +FA VFTARYLDLFT   S YN+VMKV+FL+ TY TVYLM+ KFKAT D NHDTFR EFL+ P A+LA+++NHDF+ +EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALGSYRALYILNW+YRYY ENFFD IAVV+GCVQT+LY DFFYLY+T+VLKGRKI+LPA
Sbjct:    1 MNIFRLAGDLSHLLAIIVLLVKIWKSRSCAGISGRSQALFAAVFTARYLDLFTHVYSYYNTVMKVIFLVCTYATVYLMFSKFKATYDHNHDTFRVEFLVIPAALLALVINHDFNHVEILWTFSIYLESVAILPQLFMLSKTGEAETITSHYLFALGSYRALYILNWVYRYYYENFFDPIAVVAGCVQTVLYADFFYLYVTRVLKGRKIQLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: kdelr2a (ER lumen protein-retaining receptor 2-like [Source:NCBI gene;Acc:103040303])

HSP 1 Score: 336.265 bits (861), Expect = 1.914e-115
Identity = 161/212 (75.94%), Postives = 187/212 (88.21%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGD+SHL AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFLI P   LA +VNHDFS LEI WTFSIY+E+VAILPQLFLISKTGEAE+IT+HYLF+LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLAGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRIEFLIVPVGGLAFLVNHDFSPLEIMWTFSIYLESVAILPQLFLISKTGEAETITTHYLFSLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:103025946])

HSP 1 Score: 330.102 bits (845), Expect = 4.099e-113
Identity = 157/212 (74.06%), Postives = 186/212 (87.74%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWK+RSC+GISGKSQI+FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY++NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLINWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR3 (ER lumen protein-retaining receptor 3 [Source:NCBI gene;Acc:103035602])

HSP 1 Score: 298.516 bits (763), Expect = 1.092e-100
Identity = 142/212 (66.98%), Postives = 181/212 (85.38%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+SHLVAII+L LKIW+++SC+GISGKSQ++FA+VFT RYLDLFT F+SIYN+VMKV+FL+  Y TVYL++ +F+ + DS +D+FR EFL+ P A L+ + N+ F+ LEI WTFSIY+E+VAILPQLF+I+KTGEAESIT+HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSHLVAIILLFLKIWRSKSCAGISGKSQVLFAVVFTTRYLDLFTGFISIYNTVMKVVFLVLAYATVYLIYLRFRNSYDSENDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITTHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000042346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000042346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 139.813 bits (351), Expect = 3.771e-39
Identity = 99/227 (43.61%), Postives = 125/227 (55.07%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTAR-YLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLE-------------IFWTFSIYMEAVAILPQLFLISKTGEAESI-TSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+S    + + L         +GISGKSQ+   L  +    L   T F+SIYN+VMKV  L G  I +  ++      N  ++D+       G C  +A       SFLE             I WTFSIY+E+V           TGEAES    HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSAFSCLCVCLCVC------AGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGCLPGVGIPLQFIYSTCAFRN--SYDSGMHFISGGSCCSVA-----GLSFLEKLTPSTPTGGNTPILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 203

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000040094.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000040094.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 7.126e-36
Identity = 90/214 (42.06%), Postives = 113/214 (52.80%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTAR-YLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESI-TSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRL GD+S     + L +       C+GISGKSQ+   L  +    L   T F+SIYN+VMKV     T+               ++  T                        +I WTFSIY+E+V           TGEAES    HYLF LG YRALY+ NW++RY+ E+FFD IAVVSG VQTI YCDFFYLY T+VL+G  K+ LP
Sbjct:    1 MNVFRLCGDVSAFSLCVCLCV-------CAGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGKHKHTHKHHTQHTHTHTPHTHTHTTTHPHS--------------------QILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 176

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 310.842 bits (795), Expect = 3.300e-106
Identity = 155/212 (73.11%), Postives = 192/212 (90.57%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRLAGD+SHL+AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL T+++S+YN+ MKV+++  +Y TV++++ KFKAT DSNHDTFR EFL+ P A+L+++VNHD+S +EI WTFSIY+E+VAILPQLF++SKTGEAE+ITSHYLFALG YR LY+ NWI+RY+ E FFDLIA+V+G VQTILYCDFFYLYITKVLKG+K+ LPA
Sbjct:    1 MNVFRLAGDLSHLLAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTNYISLYNTTMKVIYIGCSYATVWMIYSKFKATYDSNHDTFRVEFLVLPVALLSLVVNHDYSVVEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYFAEGFFDLIAIVAGLVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 310.457 bits (794), Expect = 5.387e-106
Identity = 157/212 (74.06%), Postives = 190/212 (89.62%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MN+FRL GD+SHL+AIIILL+KIWKTRSC+GISGKSQI+FALVFT RYLDLFT+F+SIYN+ MKV+++   Y T+++++ KFKAT D N+DTFR EFL+ P   L+++VNHDFS LEI WTFSIY+E+VAILPQLFL+SKTGEAE+ITSHYLFALG YRALY+LNWI+RYY E FFDLIA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNVFRLTGDLSHLLAIIILLIKIWKTRSCAGISGKSQILFALVFTTRYLDLFTTFISIYNTSMKVVYMACAYATLWMIYHKFKATYDGNNDTFRVEFLVVPIGGLSVLVNHDFSLLEILWTFSIYLESVAILPQLFLVSKTGEAETITSHYLFALGLYRALYLLNWIWRYYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Match: ERD2 (HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136])

HSP 1 Score: 206.453 bits (524), Expect = 1.754e-65
Identity = 108/218 (49.54%), Postives = 155/218 (71.10%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFT-SFVSIYNSVMKVLFLLGT-YITVYLMWFKFKATNDSN----HDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGEN-FFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 740
            MN FR+ GD+SHL +I+IL+  I  TR   GIS K+Q ++ALVF  RYLDL T  +VS+YN++MK+ F++ T YI V L   K   T   N    HDTF+ + L+   A++++  +H F+FLE+ W+FS+++E+VAILPQL+++SK G+  S+T HY+FA+G YRALYI NWI+RY  E+   D IA  +G +QT+LY DFFY+Y TKV++G+  +LP
Sbjct:    1 MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP 218

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Match: EDO48388 (ER lumen protein retaining receptor [Source:UniProtKB/TrEMBL;Acc:A7RJJ4])

HSP 1 Score: 342.428 bits (877), Expect = 2.106e-118
Identity = 160/212 (75.47%), Postives = 190/212 (89.62%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHLVAII+LL KIWKTRSC+G+SGKSQ+MFALVF+ RYLDLFTSFVS+YNSVMKV+++   + T+YLM+ KFKAT DSNHDTFR EFL+ P A LA +VNH+F+ +E+ WTFSIY+E+VAILPQLF+ISKTGEAESITSHYLFALG+YRALYI NW+YRYY E F+D IA+V+GCVQT LYCDFFYLYITKVLKG+ ++LPA
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr2b (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101160362])

HSP 1 Score: 330.487 bits (846), Expect = 2.577e-113
Identity = 157/212 (74.06%), Postives = 185/212 (87.26%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+GISGKSQ++FALVFT RYLDL TSF+S+YN+ MKV+++   Y TVYL++ KFKAT D NHDTFR EFL+ P   LA +VNHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQTILYCDFFYLY+TKVLKG+K+ LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYVKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: KDELR2 (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101157057])

HSP 1 Score: 331.643 bits (849), Expect = 9.511e-113
Identity = 155/212 (73.11%), Postives = 187/212 (88.21%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+GISGKSQI+FALVFT RYLDL TSF+S+YNS MKV+++  +Y TVYL++ KF+AT D NHD+FR EFL+ P   LA+++NHDFS LEI WTFSIY+E+VAILPQLF+ISKTGEAE+IT+HYLF LG YRALY+ NWI+R+Y E FFD+IA+V+G VQT+LYCDFFYLY+TKVLKG+K+ LPA
Sbjct:   60 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNSSMKVIYIGCSYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 271

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:101155114])

HSP 1 Score: 298.516 bits (763), Expect = 1.223e-100
Identity = 144/212 (67.92%), Postives = 181/212 (85.38%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGR-KIRLP 740
            MN+FRLAGD+SHLVAIIILLLKIW++RSC+GISGKSQ++FA+VFT RYLDLFT F+S YN++MKV+FL  +Y TVYL++ +FK T +S +D+FR EFL+ P   L+ + N+ F+ LEI WTFSI++E+VAI+PQLF+I+KTGEAESIT+HYLF LG YRALYI NW++RY+ E FFD IAVVSG VQTI Y DFFYLY+TKVL+GR K+ LP
Sbjct:    1 MNVFRLAGDVSHLVAIIILLLKIWRSRSCAGISGKSQVLFAIVFTTRYLDLFTIFISPYNTIMKVVFLALSYATVYLIYVRFKNTFNSENDSFRLEFLLVPVIGLSFLENYAFTPLEILWTFSIFLESVAIMPQLFMITKTGEAESITTHYLFFLGLYRALYIANWVWRYHTEGFFDQIAVVSGVVQTIFYIDFFYLYVTKVLRGRGKMTLP 212

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BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 430.639 bits (1106), Expect = 6.624e-153
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 353.599 bits (906), Expect = 4.229e-123
Identity = 174/174 (100.00%), Postives = 174/174 (100.00%), Query Frame = 3

Query:  222 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 174

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000073757.1 (SMESG000073757.1)

HSP 1 Score: 297.36 bits (760), Expect = 2.002e-100
Identity = 137/203 (67.49%), Postives = 174/203 (85.71%), Query Frame = 3

Query:  135 MSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MSHL+AII+LL KIWK+RSC+G+SGKSQIMFA+VF  RYLDLF  ++S+YN +MK  F++ + +TVY ++FKFKAT D NHD+FR EF++ P   LA+++NH FSF+EI WT+SIY+E++AILPQL+LISKTGEAE+ITSHYLFALG YRA YILNW YR++ E+F+DLIA+ SG +QTILYCDFFYLY+TKVLKG+   LPA
Sbjct:    1 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 203

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000053522.1 (SMESG000053522.1)

HSP 1 Score: 289.656 bits (740), Expect = 2.300e-97
Identity = 136/212 (64.15%), Postives = 171/212 (80.66%), Query Frame = 3

Query:  108 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MNIFRL GD+SHL AIIILLLKIWKTRSC+G+SGK+QI+F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    1 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 280.796 bits (717), Expect = 5.526e-95
Identity = 135/135 (100.00%), Postives = 135/135 (100.00%), Query Frame = 3

Query:  339 MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 743
            MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA
Sbjct:    1 MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 135

The following BLAST results are available for this feature:

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KDELR2	6.469e-115	75.47	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	1.056e-103	68.72	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	3.870e-102	71.70	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	5.821e-97	68.66	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	6.402e-74	71.33	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
erd-2.1	2.374e-103	65.22	ER lumen protein-retaining receptor [Source:UniPr...	[more]
erd-2.2	2.482e-99	69.34	Putative ER lumen protein-retaining receptor C28H8...	[more]
erd-2.2	2.482e-99	69.34	Putative ER lumen protein-retaining receptor C28H8...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KdelR	3.035e-117	73.58	gene:FBgn0267330 transcript:FBtr0080021	[more]
KdelR	3.035e-117	73.58	gene:FBgn0267330 transcript:FBtr0080023	[more]
KdelR	3.035e-117	73.58	gene:FBgn0267330 transcript:FBtr0080022	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kdelr2a	1.933e-112	73.58	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2b	4.146e-112	73.11	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	2.050e-96	65.09	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	2.050e-96	65.09	KDEL endoplasmic reticulum protein retention recep...	[more]
CABZ01075611.1	3.588e-53	61.59	pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDA...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
kdelr1	3.315e-112	73.11	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2	5.240e-112	72.17	KDEL endoplasmic reticulum protein retention recep...	[more]
stx1a	1.609e-91	67.96	syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753]	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kdelr2	4.342e-114	74.53	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr3	4.719e-103	66.04	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	4.481e-102	71.23	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	8.327e-74	70.67	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	6.235e-55	67.88	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O76767\|ERD2_DROME	3.043e-116	73.58	ER lumen protein-retaining receptor OS=Drosophila ...	[more]
sp\|P33947\|ERD22_HUMAN	3.107e-114	75.47	ER lumen protein-retaining receptor 2 OS=Homo sapi...	[more]
sp\|Q5ZKX9\|ERD22_CHICK	2.415e-113	74.53	ER lumen protein-retaining receptor 2 OS=Gallus ga...	[more]
sp\|Q5U305\|ERD22_RAT	3.037e-113	74.53	ER lumen protein-retaining receptor 2 OS=Rattus no...	[more]
sp\|Q9CQM2\|ERD22_MOUSE	3.037e-113	74.53	ER lumen protein-retaining receptor 2 OS=Mus muscu...	[more]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A077Z6A3	1.503e-118	77.36	ER lumen protein-retaining receptor OS=Trichuris t...	[more]
A0A1V9WYN6	1.790e-118	73.58	ER lumen protein-retaining receptor OS=Tropilaelap...	[more]
A0A085N272	3.761e-118	77.36	ER lumen protein-retaining receptor OS=Trichuris s...	[more]
A0A067QLS7	1.913e-117	75.94	ER lumen protein-retaining receptor OS=Zootermopsi...	[more]
A0A5S6QP95	4.631e-117	76.89	ER lumen protein-retaining receptor OS=Trichuris m...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kdelr2a	1.914e-115	75.94	ER lumen protein-retaining receptor 2-like [Source...	[more]
KDELR2	4.099e-113	74.06	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	1.092e-100	66.98	ER lumen protein-retaining receptor 3 [Source:NCBI...	[more]
ENSAMXT00000042346.1	3.771e-39	43.61	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000040094.1	7.126e-36	42.06	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
KDELR1	3.300e-106	73.11	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	5.387e-106	74.06	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ERD2	1.754e-65	49.54	HDEL receptor; an integral membrane protein that b...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO48388	2.106e-118	75.47	ER lumen protein retaining receptor [Source:UniPr...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
kdelr2b	2.577e-113	74.06	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
KDELR2	9.511e-113	73.11	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
kdelr3	1.223e-100	67.92	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064394.1	6.624e-153	100.00	SMESG000064394.1	[more]
SMESG000064394.1	4.229e-123	100.00	SMESG000064394.1	[more]
SMESG000073757.1	2.002e-100	67.49	SMESG000073757.1	[more]
SMESG000053522.1	2.300e-97	64.15	SMESG000053522.1	[more]
SMESG000064394.1	5.526e-95	100.00	SMESG000064394.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30033329 ID=SMED30033329|Name=ER lumen protein-retaining receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1204bp
TTTAACTTAAATCTTTAAATGACCTTAAAACTTCTTTAAATTATTCAGCG
AATTTATTGACACGTTTGTTTGTGTAAACATATTTGAAAATTAATTAATA
GGACAAGATGAATATATTTAGATTAGCGGGTGATATGTCCCATTTAGTGG
CCATAATAATTTTGCTTCTTAAAATTTGGAAAACTAGATCTTGTTCAGGA
ATATCTGGAAAAAGTCAAATTATGTTTGCTTTGGTCTTTACAGCTAGATA
TTTAGACTTGTTTACGTCATTTGTATCCATATATAATTCTGTTATGAAAG
TTTTGTTCCTATTAGGAACATATATTACTGTATATTTAATGTGGTTCAAA
TTTAAAGCCACAAATGACAGTAATCATGATACATTTCGTTTTGAGTTTCT
TATTGGTCCATGTGCAATATTAGCAATTATTGTCAATCATGATTTCTCTT
TTCTTGAGATATTTTGGACCTTTTCTATTTACATGGAAGCAGTTGCTATT
TTACCCCAATTATTTTTAATTAGTAAAACTGGCGAAGCTGAATCGATAAC
TTCACATTACCTTTTTGCACTCGGTTCATATAGGGCGTTGTACATTTTGA
ATTGGATATATCGATATTACGGGGAGAATTTCTTTGATTTGATAGCCGTT
GTTTCTGGGTGTGTTCAAACGATTCTCTACTGTGATTTCTTTTATCTCTA
TATTACGAAAGTGCTGAAAGGACGCAAGATCAGGTTGCCGGCTTGAATGG
TGCGCGATCGGTCGATCAATGAGTTCCTGTTCTGTTGATGTTGCTGTTCA
TTAGCTGTGTAGCTTTTTTGAAATTGAAAAATGGTTTTTTTGTCGAACTT
GTAATAAATCTTGTTTCGTATTTTGATTTTCTTGTTGTGTTTGAATTTTG
CAATGTGACAATTTTCAAATATTATAAATTTATTCCATATGTGAGATGAT
AATGATGATAATAATGATTGTCAGAGTTTTCAGTTTCTTTTGTATGTTTA
TTTGATCATATTGATTTAAAGAAATGTGAATTATTGATTTTATATAAGTG
CTTTCTTCTGGTCTTTATAAATACAAAGGTGTTTGTGTTGTTATTGTTTG
CTGATCAGTCCATTAATGAAAATTCATTGAGCATTTCACTTGCTTGTAGG
GCATTTCGTATTCGCTTGCACACCTTTGGTATTTAAAGATAACCGGTATG
GGCA

protein sequence of SMED30033329-orf-1

>SMED30033329-orf-1 ID=SMED30033329-orf-1|Name=SMED30033329-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=213bp
MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLD
LFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIG
PCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSH
YLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYIT
KVLKGRKIRLPA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002032	epidermal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000133	ER_ret_rcpt

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0030140	trans-Golgi network transport vesicle

Vocabulary: **biological process**
Term	Definition
GO:0006621	protein retention in ER lumen
GO:0006810	transport
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0019233	sensory perception of pain

Vocabulary: **molecular function**
Term	Definition
GO:0046923	ER retention sequence binding
GO:0005046	KDEL sequence binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000133	ER lumen protein retaining receptor	PRINTS	PR00660	ERLUMENR	coord: 52..68 score: 55.88 coord: 120..140 score: 75.85 coord: 31..51 score: 74.49 coord: 156..174 score: 69.55 coord: 4..23 score: 67.14 coord: 184..199 score: 75.0 coord: 142..156 score: 73.81
IPR000133	ER lumen protein retaining receptor	PFAM	PF00810	ER_lumen_recept	coord: 28..169 e-value: 3.5E-54 score: 183.6
IPR000133	ER lumen protein retaining receptor	PANTHER	PTHR10585	ER LUMEN PROTEIN RETAINING RECEPTOR	coord: 1..212
None	No IPR available	PANTHER	PTHR10585:SF37	ER LUMEN PROTEIN-RETAINING RECEPTOR 2	coord: 1..212
None	No IPR available	TMHMM	TMhelix		coord: 151..168
None	No IPR available	TMHMM	TMhelix		coord: 178..200
None	No IPR available	TMHMM	TMhelix		coord: 119..138
None	No IPR available	TMHMM	TMhelix		coord: 92..109
None	No IPR available	TMHMM	TMhelix		coord: 58..80