slc39a-4

Overview


Name	slc39a-4 (AKN21669.1)
Smed ID	SMED30033279
Length (bp)	2680

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc39a-4 (SMED30033279) t-SNE clustered cells

Violin plots show distribution of expression levels for slc39a-4 (SMED30033279) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc39a-4 (SMED30033279) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc39a-4 (SMED30033279) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30033279

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30033279	h1SMcG0018659	dd_Smed_v4_6113_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30033279	h1SMcG0018659	dd_Smed_v4_6113_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30033279	h1SMcG0018659	dd_Smed_v4_6113_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30033279	h1SMcG0018659	dd_Smed_v4_6113_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of slc39a-4 vs. Ensembl Human
Match: SLC39A10 (solute carrier family 39 member 10 [Source:HGNC Symbol;Acc:HGNC:20861])

HSP 1 Score: 182.185 bits (461), Expect = 6.643e-47
Identity = 88/160 (55.00%), Postives = 117/160 (73.12%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + +  IA+ VI GDG+HNF DG+AIGAAF+  + GG+ST+IAV CHELPHELGDF VLL AGM+++ AI YNL+S++   IGM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+        +    P   F+ QN+G + G AIMLVIALYE+
Sbjct:  664 TGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823

HSP 2 Score: 72.4034 bits (176), Expect = 2.504e-12
Identity = 65/209 (31.10%), Postives = 110/209 (52.63%), Query Frame = 1

Query:  388 KCHSPIQMLSWF-NKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKP--MKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHS-------------HNGHNKM------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKK 948
            +C +  Q+L ++ +   S +S + F  LCP+LL Q+ SR+C  +  + +     K  N       N   + W+C   ++ VISL+ LL V L+PI+ +  +  +   L+ALAVG+++GDALLHL+PH+     + GH               +  NK       V K LVAL GI+L F+ E    ++++ + +R  K++ F+K  T++
Sbjct:  336 ECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHS-----QGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR-GKQKWFMKQNTEE 538

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Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + +  IA+ VI GDG+HNF DG+AIGAAF+  + GG+ST+IAV CHELPHELGDF VLL AGM+++ AI YNL+S++   IGM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+        +    P   F+ QN+G + G AIMLVIALYE+
Sbjct:  664 TGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823

HSP 2 Score: 72.4034 bits (176), Expect = 2.504e-12
Identity = 65/209 (31.10%), Postives = 110/209 (52.63%), Query Frame = 1

Query:  388 KCHSPIQMLSWF-NKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKP--MKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHS-------------HNGHNKM------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKK 948
            +C +  Q+L ++ +   S +S + F  LCP+LL Q+ SR+C  +  + +     K  N       N   + W+C   ++ VISL+ LL V L+PI+ +  +  +   L+ALAVG+++GDALLHL+PH+     + GH               +  NK       V K LVAL GI+L F+ E    ++++ + +R  K++ F+K  T++
Sbjct:  336 ECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHS-----QGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR-GKQKWFMKQNTEE 538

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BLAST of slc39a-4 vs. Ensembl Human
Match: SLC39A6 (solute carrier family 39 member 6 [Source:HGNC Symbol;Acc:HGNC:18607])

HSP 1 Score: 164.851 bits (416), Expect = 2.190e-41
Identity = 80/161 (49.69%), Postives = 111/161 (68.94%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI--LFLWQNIGFVIGSAIMLVIALYE 2106
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM+++ A+ YN +S++   +GM  G+ +G    ++S WIF LTAG+F+Y+ALVDM+PE+    L  +   H  S    F  QN G ++G  IML+I+++E
Sbjct:  590 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEM----LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746

HSP 2 Score: 55.4546 bits (132), Expect = 4.405e-7
Identity = 50/169 (29.59%), Postives = 82/169 (48.52%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---------------MDDG-------EKGHSHNGHNKMVWKSLVALIGIHLFFLTERITIL 882
            L+  +F  LCP+++ Q+ +R C  + ++    + P   T S  I      W+  F A+ +IS + LL V L+P+M + ++  +   L+ALAVG+L+GDA LHL+PH+                M  G        +    + +    WK L AL G++  FL E +  L
Sbjct:  282 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPP--KTYSLQI-----AWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTL 443

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Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI--LFLWQNIGFVIGSAIMLVIALYE 2106
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM+++ A+ YN +S++   +GM  G+ +G    ++S WIF LTAG+F+Y+ALVDM+PE+    L  +   H  S    F  QN G ++G  IML+I+++E
Sbjct:  590 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEM----LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746

HSP 2 Score: 55.4546 bits (132), Expect = 4.405e-7
Identity = 50/169 (29.59%), Postives = 82/169 (48.52%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---------------MDDG-------EKGHSHNGHNKMVWKSLVALIGIHLFFLTERITIL 882
            L+  +F  LCP+++ Q+ +R C  + ++    + P   T S  I      W+  F A+ +IS + LL V L+P+M + ++  +   L+ALAVG+L+GDA LHL+PH+                M  G        +    + +    WK L AL G++  FL E +  L
Sbjct:  282 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPP--KTYSLQI-----AWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTL 443

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BLAST of slc39a-4 vs. Ensembl Human
Match: SLC39A12 (solute carrier family 39 member 12 [Source:HGNC Symbol;Acc:HGNC:20860])

HSP 1 Score: 154.066 bits (388), Expect = 9.872e-39
Identity = 71/158 (44.94%), Postives = 113/158 (71.52%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            ++  +A  ++ GD LHNF DG+AIGAAF++    G++T IA+LCHE+PHE+GDF VLL +G+S++TAI  N +SS+   +G+ IG+ +   P +  WIF +TAGMFLY++LV+M+PE++  + +      RP ++FL QN G ++G   +L++A+YE+
Sbjct:  402 AISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQ------RPWMMFLLQNFGLILGWLSLLLLAIYEQ 553

HSP 2 Score: 70.0922 bits (170), Expect = 1.139e-11
Identity = 59/172 (34.30%), Postives = 84/172 (48.84%), Query Frame = 1

Query:  391 CHSPIQMLSWF-NKTKSGLSKEDFITLCPSLLVQMVSRVCR-PNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL----MDDGEKGHSHN--GHNKMVWKSLVALIGIHLFFLTERITIL 882
            C S  Q++  F  K  S +SKEDF  + P ++ Q++S  C  P   Q   P   +       +    A+ L + G+++  +LV            +  Y  I QL + LAVG+L+GDALLHLIP  L     +  E GH H   GH   +WK +  + GIH FFL E+  IL
Sbjct:  176 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTV----AVTLLTLGSMLGTALVLFHSC-------EENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGH---IWKLMGLIGGIHGFFLIEKCFIL 333

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BLAST of slc39a-4 vs. Ensembl Celegans
Match: zipt-15 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:U4PS08])

HSP 1 Score: 148.288 bits (373), Expect = 2.363e-39
Identity = 74/161 (45.96%), Postives = 107/161 (66.46%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-PSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLW-QNIGFVIGSAIMLVIALYEE 2109
            S++ A+A+ ++ GDGLHNF DGI+IGAAFA  +  GLS ++AVLC E PHELGD  +L+ +GM+L+ A+ YNL+S++ C +G  IGV +G+L P  S + F L  GMFLYI+L  MMPE+     +   +  R  I  L+ Q++G   G  +M ++A Y E
Sbjct:  132 SAIAAVAWMIVFGDGLHNFIDGISIGAAFAESLHSGLSISLAVLCEEFPHELGDVAILVASGMTLKQALIYNLLSAITCYVGFFIGVGIGELGPDTSKYAFGLAGGMFLYISLACMMPEMKKAMEEALNVSLRHGIYVLFLQSVGLFSGLTLMYIMARYGE 292

[Close]

BLAST of slc39a-4 vs. Ensembl Celegans
Match: zipt-15 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:U4PS08])

HSP 1 Score: 149.058 bits (375), Expect = 1.584e-38
Identity = 74/161 (45.96%), Postives = 107/161 (66.46%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-PSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLW-QNIGFVIGSAIMLVIALYEE 2109
            S++ A+A+ ++ GDGLHNF DGI+IGAAFA  +  GLS ++AVLC E PHELGD  +L+ +GM+L+ A+ YNL+S++ C +G  IGV +G+L P  S + F L  GMFLYI+L  MMPE+     +   +  R  I  L+ Q++G   G  +M ++A Y E
Sbjct:  249 SAIAAVAWMIVFGDGLHNFIDGISIGAAFAESLHSGLSISLAVLCEEFPHELGDVAILVASGMTLKQALIYNLLSAITCYVGFFIGVGIGELGPDTSKYAFGLAGGMFLYISLACMMPEMKKAMEEALNVSLRHGIYVLFLQSVGLFSGLTLMYIMARYGE 409

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BLAST of slc39a-4 vs. Ensembl Celegans
Match: zipt-17 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:Q9XVR4])

HSP 1 Score: 117.087 bits (292), Expect = 6.786e-28
Identity = 63/160 (39.38%), Postives = 98/160 (61.25%), Query Frame = 1

Query: 1627 DLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++  +K  A  ++ GDG+HN  DG+A+GA+F   +  G  T IAV+CHELPHE+GD  VL+ +G+S+ TA+  NL+S++    G+ I + LG+   I + +  +TAGMFLY+A VDM+  L    L  +  +   SIL   Q  GF +G A++  +  +E
Sbjct:  226 EICGLKPRALIILFGDGVHNLVDGLAMGASFMISVKLGFITTIAVICHELPHEIGDLAVLIDSGLSMCTALILNLLSALTAYAGLFIAIVLGRDEEIETILLAITAGMFLYVAWVDMLSHLKHDSLMADH-WMVTSIL---QLSGFTLGFALIFGLGWFE 381

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BLAST of slc39a-4 vs. Ensembl Celegans
Match: zipt-16 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:Q8I4G0])

HSP 1 Score: 96.6709 bits (239), Expect = 1.551e-20
Identity = 53/157 (33.76%), Postives = 92/157 (58.60%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-PSISSWIFMLTAGMFLYIALVDMMPEL--STRRLKGNKIFHRPSILF-LWQNIGFVIGSAIMLVIA 2097
            V ++AY +I G   +NF DG+++GAAF++++  GLS  IAV+  + P ELG   +L+ +G+ L+  + +N++  V   +G  IGV L  +  S   +IF +++GM++YI L  ++PE+  ST  L    +    SIL  + Q  G + G+  M  ++
Sbjct:  344 VASVAYMIIFGSSANNFVDGMSMGAAFSDNLLRGLSIGIAVISQQFPQELGTLAILVKSGLGLKKTLLFNMVPIVLSFLGFSIGVMLDSVDDSYDEYIFAISSGMYMYIFLGTLIPEIRESTNELIKENL--AESILVSILQACGILFGTTFMYFMS 498

[Close]

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-PSISSWIFMLTAGMFLYIALVDMMPEL--STRRLKGNKIFHRPSILF-LWQNIGFVIGSAIMLVIA 2097
            V ++AY +I G   +NF DG+++GAAF++++  GLS  IAV+  + P ELG   +L+ +G+ L+  + +N++  V   +G  IGV L  +  S   +IF +++GM++YI L  ++PE+  ST  L    +    SIL  + Q  G + G+  M  ++
Sbjct:  344 VASVAYMIIFGSSANNFVDGMSMGAAFSDNLLRGLSIGIAVISQQFPQELGTLAILVKSGLGLKKTLLFNMVPIVLSFLGFSIGVMLDSVDDSYDEYIFAISSGMYMYIFLGTLIPEIRESTNELIKENL--AESILVSILQACGILFGTTFMYFMS 498

[Close]

BLAST of slc39a-4 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0331418)

HSP 1 Score: 181.415 bits (459), Expect = 1.864e-47
Identity = 82/157 (52.23%), Postives = 114/157 (72.61%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++ A+A+ +I GDGLHNF DG+AIGAAFA +I GG ST++AV CHELPHELGDF +L+ AGMS+++A++YNL++ V   IGM+ G+  G+   ++ W+F + AG+F+YIALVDMMPE+S          H+    FL Q +G + G  IML+IALYE
Sbjct:  539 TLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISAS--------HKSLGQFLLQILGMLSGVGIMLLIALYE 687

HSP 2 Score: 73.1738 bits (178), Expect = 6.688e-13
Identity = 59/191 (30.89%), Postives = 94/191 (49.21%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSR---VCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLR---SKRKSKKQHFLKLLTKKLSLENFYSEASAGDKF 996
            LS +D + LCP LL ++ ++      P +   +   + +         +   +W+ +F +V    ++GL+ V +IP M   YY  I Q L+ALAVG++ GDALLHL+PH+L    E+G        M+ K L  L GI  F++ E    +    R    K+++KK    K++    S  N    + AGDK 
Sbjct:  210 LSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKD--KDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERG--------MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVN---NSVAGDKI 387

[Close]

BLAST of slc39a-4 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0345601)

HSP 1 Score: 181.415 bits (459), Expect = 1.864e-47
Identity = 82/157 (52.23%), Postives = 114/157 (72.61%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++ A+A+ +I GDGLHNF DG+AIGAAFA +I GG ST++AV CHELPHELGDF +L+ AGMS+++A++YNL++ V   IGM+ G+  G+   ++ W+F + AG+F+YIALVDMMPE+S          H+    FL Q +G + G  IML+IALYE
Sbjct:  539 TLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISAS--------HKSLGQFLLQILGMLSGVGIMLLIALYE 687

HSP 2 Score: 73.1738 bits (178), Expect = 6.688e-13
Identity = 59/191 (30.89%), Postives = 94/191 (49.21%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSR---VCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLR---SKRKSKKQHFLKLLTKKLSLENFYSEASAGDKF 996
            LS +D + LCP LL ++ ++      P +   +   + +         +   +W+ +F +V    ++GL+ V +IP M   YY  I Q L+ALAVG++ GDALLHL+PH+L    E+G        M+ K L  L GI  F++ E    +    R    K+++KK    K++    S  N    + AGDK 
Sbjct:  210 LSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKD--KDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERG--------MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVN---NSVAGDKI 387

[Close]

BLAST of slc39a-4 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0331417)

HSP 1 Score: 181.415 bits (459), Expect = 1.864e-47
Identity = 82/157 (52.23%), Postives = 114/157 (72.61%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++ A+A+ +I GDGLHNF DG+AIGAAFA +I GG ST++AV CHELPHELGDF +L+ AGMS+++A++YNL++ V   IGM+ G+  G+   ++ W+F + AG+F+YIALVDMMPE+S          H+    FL Q +G + G  IML+IALYE
Sbjct:  539 TLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISAS--------HKSLGQFLLQILGMLSGVGIMLLIALYE 687

HSP 2 Score: 73.1738 bits (178), Expect = 6.688e-13
Identity = 59/191 (30.89%), Postives = 94/191 (49.21%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSR---VCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLR---SKRKSKKQHFLKLLTKKLSLENFYSEASAGDKF 996
            LS +D + LCP LL ++ ++      P +   +   + +         +   +W+ +F +V    ++GL+ V +IP M   YY  I Q L+ALAVG++ GDALLHL+PH+L    E+G        M+ K L  L GI  F++ E    +    R    K+++KK    K++    S  N    + AGDK 
Sbjct:  210 LSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKD--KDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERG--------MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVN---NSVAGDKI 387

[Close]

BLAST of slc39a-4 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0076624)

HSP 1 Score: 181.415 bits (459), Expect = 1.864e-47
Identity = 82/157 (52.23%), Postives = 114/157 (72.61%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++ A+A+ +I GDGLHNF DG+AIGAAFA +I GG ST++AV CHELPHELGDF +L+ AGMS+++A++YNL++ V   IGM+ G+  G+   ++ W+F + AG+F+YIALVDMMPE+S          H+    FL Q +G + G  IML+IALYE
Sbjct:  539 TLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISAS--------HKSLGQFLLQILGMLSGVGIMLLIALYE 687

HSP 2 Score: 73.1738 bits (178), Expect = 6.688e-13
Identity = 59/191 (30.89%), Postives = 94/191 (49.21%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSR---VCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLR---SKRKSKKQHFLKLLTKKLSLENFYSEASAGDKF 996
            LS +D + LCP LL ++ ++      P +   +   + +         +   +W+ +F +V    ++GL+ V +IP M   YY  I Q L+ALAVG++ GDALLHL+PH+L    E+G        M+ K L  L GI  F++ E    +    R    K+++KK    K++    S  N    + AGDK 
Sbjct:  210 LSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKD--KDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERG--------MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVN---NSVAGDKI 387

[Close]

BLAST of slc39a-4 vs. Ensembl Fly
Match: Zip71B (gene:FBgn0036461 transcript:FBtr0113171)

HSP 1 Score: 142.895 bits (359), Expect = 2.512e-35
Identity = 74/159 (46.54%), Postives = 101/159 (63.52%), Query Frame = 1

Query: 1648 IAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-PSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL-----FLWQNIGFVIGSAIMLVIALYE 2106
            +A+ VI GDGLHN  DG+AIGAAFA+D   G +TA AVLCHELPHELGDF +LL  G+S+R A++ N++SSV   +GM +G+ +  +   ++ WI+  TAG FLYIA  D++P +S        + H P         + Q  G ++G  IML IAL E
Sbjct:  412 VAFMVIIGDGLHNLTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFALLLQTGVSMRRAVYMNIVSSVLSFVGMSVGLFIAGIGDGMTQWIYAATAGSFLYIAFADLVPTMS--------VAHNPEKAKDPKGIIIQIFGILLGGLIMLAIALNE 562

HSP 2 Score: 58.9214 bits (141), Expect = 1.804e-8
Identity = 56/192 (29.17%), Postives = 102/192 (53.12%), Query Frame = 1

Query:  268 KNSSDNMSAFLSSEGFSSLILK-------LGLRK---RNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM 813
            + SS+ ++A LS +   SLI+        +  RK   +N++S T + V    +S  +   + N  +  ++   F+ LCP+LL Q+ + VC+    QP      +N+ +  +       W+ +   ++++S  GLL + L+P+M  + Y  I + L+++AVG+LAGDAL+HL+PHAL  + +      G N +
Sbjct:  139 RESSEPVAACLSPKSLLSLIVNHNDLHKNIAYRKLLIKNDVSST-DGVH---NSEEEYNEFINSVR--ITPRAFMKLCPALLAQIDNGVCK----QPAVRSVNLNDKNQKI----WYAWIYASITMLILSACGLLGILLVPLMKSAAYQEILKFLVSIAVGTLAGDALMHLLPHALFKEEKHEEEVTGINPL 316

[Close]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Match: slc39a10 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:393644])

HSP 1 Score: 185.652 bits (470), Expect = 4.066e-48
Identity = 88/163 (53.99%), Postives = 122/163 (74.85%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEEH 2112
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++    GMVIG  +G+   +++SWIF +TAGMFLY+ALVDM+PE+    L G+   H+   +  F+ QN G + G  IML+IA++E+H
Sbjct:  682 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYAGMVIGTAVGQYTHNVTSWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRCEMGHFVLQNFGMLTGFGIMLLIAIFEDH 840

HSP 2 Score: 73.9442 bits (180), Expect = 5.871e-13
Identity = 60/188 (31.91%), Postives = 95/188 (50.53%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM--------------VWKSLVALIGIHLFFLTERITILYQNLRSKR 906
            +C +  Q+L  +   + S +S   F  LCP+LL Q+  R C  +                 V  ++  +W+  F ++ +ISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+  D     H HN   +M              VWK L AL GI+L F+ E    ++++   +R
Sbjct:  382 ECLNLTQLLHQYGLSSDSLISPVQFTYLCPALLYQIDRRFCILHYHHV--------EAEEQVAPSSGWVWMWGFVSITIISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHSQGD-----HDHNHGEQMEEEPEVDFLIKFDGVWKGLTALAGIYLLFIIEHCIGMFKHYSDQR 556

[Close]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Match: slc39a10 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:393644])

HSP 1 Score: 184.882 bits (468), Expect = 7.557e-48
Identity = 88/163 (53.99%), Postives = 122/163 (74.85%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEEH 2112
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++    GMVIG  +G+   +++SWIF +TAGMFLY+ALVDM+PE+    L G+   H+   +  F+ QN G + G  IML+IA++E+H
Sbjct:  726 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYAGMVIGTAVGQYTHNVTSWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRCEMGHFVLQNFGMLTGFGIMLLIAIFEDH 884

HSP 2 Score: 73.9442 bits (180), Expect = 5.683e-13
Identity = 60/188 (31.91%), Postives = 95/188 (50.53%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM--------------VWKSLVALIGIHLFFLTERITILYQNLRSKR 906
            +C +  Q+L  +   + S +S   F  LCP+LL Q+  R C  +                 V  ++  +W+  F ++ +ISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+  D     H HN   +M              VWK L AL GI+L F+ E    ++++   +R
Sbjct:  426 ECLNLTQLLHQYGLSSDSLISPVQFTYLCPALLYQIDRRFCILHYHHV--------EAEEQVAPSSGWVWMWGFVSITIISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHSQGD-----HDHNHGEQMEEEPEVDFLIKFDGVWKGLTALAGIYLLFIIEHCIGMFKHYSDQR 600

[Close]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Match: slc39a6 (solute carrier family 39 member 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3023])

HSP 1 Score: 175.252 bits (443), Expect = 3.985e-45
Identity = 83/160 (51.88%), Postives = 114/160 (71.25%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGMS+R A+ YNL+S++   +GM+IG+ +G    ++++WIF LTAG+F+Y+ALVDM+PE+           H     FL QN G ++G  IML+IA++E+
Sbjct:  577 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMSVRQAMLYNLLSALMGYLGMIIGILIGHYAENVATWIFALTAGLFMYVALVDMVPEMLHNDASEAGFSHYG--FFLLQNAGILLGFGIMLIIAVFED 734

HSP 2 Score: 62.003 bits (149), Expect = 2.641e-9
Identity = 67/218 (30.73%), Postives = 102/218 (46.79%), Query Frame = 1

Query:  427 KTKSGLSKEDFITLCPSLLVQMVSRVC------------------RPNVTQPMKPMKPMNNTSSPVINNN--LAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN----KMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSE 1008
            + ++ LS +DF  LCP+LL+Q+ S+ C                    +         P N+T+     N      WL  F ++ +ISL+ L+ V LIP+M +  +N +   L+ALAVG+L+GDALLHLIPH+           +       + VW  L AL G+++ FL E    L +  + K + K Q  + L T+ L  E   S      K E +E
Sbjct:  278 RKEASLSVKDFSFLCPALLMQIDSKSCIVHEDEDEHSDHSHHHKHHHHHHDHQHLQHPHNHTNGRGQRNTPVYIAWLGGFLSITLISLLALVGVVLIPLMNRVCFNFLLSFLVALAVGTLSGDALLHLIPHSQGHHHHGHSEEHAEEEDSLRPVWTGLTALSGVYIMFLIEHFLTLGKMYKDKNQ-KVQKRVDLTTEVLESEKLPSLEENDVKIEAAE 494

[Close]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Match: BX119991.1 (solute carrier family 39 member 5 [Source:NCBI gene;Acc:561758])

HSP 1 Score: 152.91 bits (385), Expect = 2.201e-38
Identity = 78/161 (48.45%), Postives = 106/161 (65.84%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLG-KLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            + ++++A+ V+ GDG+HN  DG+AIG AF+  + GG STAIAV CHELPHELGD  VLL AG  +R  + ++ +S++   +G++ G  LG    S S WI  LTAG+FLY+AL DMMPE+    L G      P   FL Q +G + G AIML IAL+E+H
Sbjct:  414 TGIRSMAWMVVMGDGIHNLTDGLAIGVAFSQSLTGGFSTAIAVFCHELPHELGDLAVLLSAGWPVRRLLVFSGLSALLGFVGVLAGSALGNHWASHSPWILTLTAGVFLYVALADMMPEM----LHGACGSVSPLKRFLLQALGLLTGGAIMLCIALFEDH 570

HSP 2 Score: 60.4622 bits (145), Expect = 7.799e-9
Identity = 67/228 (29.39%), Postives = 106/228 (46.49%), Query Frame = 1

Query:  265 LKNSSDNMSAFLSSE---GFSSLILKLGLRKRNNIS-------KTFNNVSIKCHSPIQMLSWFNKTK-SGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSK 915
            L+ S D  SA   S    G S   L   LR +   S        T  ++   C +  Q+L  F   + S ++   F  LCP+LL Q+ S VC       ++  +  + TS       +A+   S  A++VISL  L+ + + P++  S        +  +AVG+L GDALLHL+PHA+         H  H   V+K L  L G++L F+ E +  L Q+ ++ ++ K
Sbjct:  163 LRESLDAKSALSGSPAELGRSDYFLHPALRNKQEESVSLLSDHPTEKHLHGNCLNVTQLLWNFGLGQASHITPAHFTFLCPALLYQIESGVC-------LRHTEDHSQTSKTSEGFLIALGWASL-ALLVISLPSLVALGMAPLLQPSVLQVFLCPMAGMAVGTLCGDALLHLMPHAIFSQ------HTDHQNAVFKGLSVLGGLYLLFIFESLLGLKQHFKNLKRRK 376

[Close]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Match: slc39a5 (solute carrier family 39 member 5 [Source:ZFIN;Acc:ZDB-GENE-060608-1])

HSP 1 Score: 152.14 bits (383), Expect = 2.755e-38
Identity = 78/161 (48.45%), Postives = 106/161 (65.84%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLG-KLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            + ++++A+ V+ GDG+HN  DG+AIG AF+  + GG STAIAV CHELPHELGD  VLL AG  +R  + ++ +S++   +G++ G  LG    S S WI  LTAG+FLY+AL DMMPE+    L G      P   FL Q +G + G AIML IAL+E+H
Sbjct:  386 TGIRSMAWMVVMGDGIHNLTDGLAIGVAFSQSLTGGFSTAIAVFCHELPHELGDLAVLLSAGWPVRRLLVFSGLSALLGFVGVLAGSALGNHWASHSPWILTLTAGVFLYVALADMMPEM----LHGACGSVSPLKRFLLQALGLLTGGAIMLCIALFEDH 542

HSP 2 Score: 60.8474 bits (146), Expect = 5.614e-9
Identity = 62/228 (27.19%), Postives = 99/228 (43.42%), Query Frame = 1

Query:  265 LKNSSDNMSAFLSSE---GFSSLILKLGLRKRNNIS-------KTFNNVSIKCHSPIQMLSWFNKTK-SGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSK 915
            L+ S D  SA   S    G S   L   LR +   S        T  ++   C +  Q+L  F   + S ++   F  LCP+LL Q+ S VC  +     +  K        +   +LA+ + S           L+ + + P++  S        +  +AVG+L GDALLHL+PHA+         H  H   V+K L  L G++L F+ E +  L Q+ ++ ++ K
Sbjct:  135 LRESLDAKSALSGSPAELGRSDYFLHPALRNKQEESVSLLSDHPTEKHLHGNCLNVTQLLWNFGLGQASHITPAHFTFLCPALLYQIESGVCLRHTEDHSQASKTSEGFLIALGWASLALLVISL--------PSLVALGMAPLLQPSVLQVFLCPMAGMAVGTLCGDALLHLMPHAIFSQ------HTDHQNAVFKGLSVLGGLYLLFIFESLLGLKQHFKNLKRRK 348

[Close]

BLAST of slc39a-4 vs. Ensembl Xenopus
Match: ENSXETT00000051316.1 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:100493171])

HSP 1 Score: 181.415 bits (459), Expect = 1.235e-46
Identity = 84/160 (52.50%), Postives = 119/160 (74.38%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + + +IA+ VI GDG+HNF DG+AIGAAF+  I GG+ST++AV CHELPHELGDF VLL AGM+++ AI YNL+S++   +GM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+     +  +  H     F+ +N+G ++G  IML+IALYE+
Sbjct:  667 TGIASIAWMVIMGDGMHNFSDGLAIGAAFSAGITGGISTSVAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYVGMLIGTAVGQYANNITLWIFAITAGMFLYVALVDMLPEMLHGDGEHEENGHCAVGQFILKNLGLLLGFTIMLLIALYED 826

HSP 2 Score: 74.7146 bits (182), Expect = 5.644e-13
Identity = 72/224 (32.14%), Postives = 113/224 (50.45%), Query Frame = 1

Query:  391 CHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL--MDDGEKG--HSHNGHNKM---------------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFED 1002
            C +  Q+L ++     S +S + F  +CP+L+ Q+ SR+C       +K    +   +        + W+C   ++ VISL+ LL V LIPI+ +  +  +   L+ALAVG+L+GDALLHL+PH+    D G +   HSH  HN                 V K LVAL GI+L F+ E    ++++ + +R  K+    K L +K  L+    EA+ G K  D
Sbjct:  347 CLNITQLLHYYGLNANSPISPDQFAYICPALVYQIDSRLC-------IKHFSDLQVENVEKSKAGASAWICGLISITVISLLSLLGVILIPIINQGCFKYLLNFLVALAVGTLSGDALLHLLPHSQGGHDHGTEAPNHSHE-HNHESLHSEDQSFLSEYDGVMKGLVALGGIYLLFIVENCLWMFKHYK-ERMGKR----KWLKRKQKLD----EAAVGRKLSD 553

[Close]

BLAST of slc39a-4 vs. Ensembl Xenopus
Match: ENSXETT00000051324.1 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:100493171])

HSP 1 Score: 181.03 bits (458), Expect = 1.351e-46
Identity = 84/160 (52.50%), Postives = 119/160 (74.38%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + + +IA+ VI GDG+HNF DG+AIGAAF+  I GG+ST++AV CHELPHELGDF VLL AGM+++ AI YNL+S++   +GM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+     +  +  H     F+ +N+G ++G  IML+IALYE+
Sbjct:  649 TGIASIAWMVIMGDGMHNFSDGLAIGAAFSAGITGGISTSVAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYVGMLIGTAVGQYANNITLWIFAITAGMFLYVALVDMLPEMLHGDGEHEENGHCAVGQFILKNLGLLLGFTIMLLIALYED 808

HSP 2 Score: 74.7146 bits (182), Expect = 5.339e-13
Identity = 72/224 (32.14%), Postives = 113/224 (50.45%), Query Frame = 1

Query:  391 CHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL--MDDGEKG--HSHNGHNKM---------------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFED 1002
            C +  Q+L ++     S +S + F  +CP+L+ Q+ SR+C       +K    +   +        + W+C   ++ VISL+ LL V LIPI+ +  +  +   L+ALAVG+L+GDALLHL+PH+    D G +   HSH  HN                 V K LVAL GI+L F+ E    ++++ + +R  K+    K L +K  L+    EA+ G K  D
Sbjct:  329 CLNITQLLHYYGLNANSPISPDQFAYICPALVYQIDSRLC-------IKHFSDLQVENVEKSKAGASAWICGLISITVISLLSLLGVILIPIINQGCFKYLLNFLVALAVGTLSGDALLHLLPHSQGGHDHGTEAPNHSHE-HNHESLHSEDQSFLSEYDGVMKGLVALGGIYLLFIVENCLWMFKHYK-ERMGKR----KWLKRKQKLD----EAAVGRKLSD 535

[Close]

BLAST of slc39a-4 vs. Ensembl Xenopus
Match: rabl6 (RAB, member RAS oncogene family like 6 [Source:Xenbase;Acc:XB-GENE-1014126])

HSP 1 Score: 152.91 bits (385), Expect = 2.333e-42
Identity = 69/151 (45.70%), Postives = 101/151 (66.89%), Query Frame = 1

Query: 1660 VIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            +  GD +HNF DG+AIGAAF+     GL+T++AVLCHELPHELGDF  LLHAG+ +R A+  N  S++   IG+ I + +    ++  WIF +  G+FLY+AL DM+P +   +L      HRP ILF   N+G ++G  I+L+++LYE++
Sbjct:    2 ITIGDAIHNFADGLAIGAAFSTSWKTGLATSLAVLCHELPHELGDFAALLHAGLRVRWALLLNFSSALTAFIGLYISLSISADEAVQQWIFTVATGLFLYVALADMLPAMMNVKL------HRPWILFFLHNLGILLGWVILLILSLYEDN 146

[Close]

BLAST of slc39a-4 vs. Ensembl Xenopus
Match: tmem135 (transmembrane protein 135 [Source:Xenbase;Acc:XB-GENE-954105])

HSP 1 Score: 154.451 bits (389), Expect = 8.592e-39
Identity = 74/158 (46.84%), Postives = 107/158 (67.72%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIG-VQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            +  I + V+ GDG+HNF DG+AIGAAF++   GGLST +AV CHELPHELGDF VLL +G+ +R  +F++L+S+     GM+IG V       I+ WIF  TAG+FLY+ALVDM+P++  R    +    +  ++    ++GF++G AIM  IALY++
Sbjct:  417 ITEIVWMVLLGDGIHNFTDGLAIGAAFSSGFSGGLSTTVAVFCHELPHELGDFAVLLQSGVPVRKVLFFSLVSAFLSFFGMIIGAVASQNSAQITPWIFAATAGIFLYVALVDMLPQMLHRE-TADPCQGKDCVI---HSLGFLLGCAIMFCIALYQD 570

HSP 2 Score: 70.8626 bits (172), Expect = 5.698e-12
Identity = 62/174 (35.63%), Postives = 89/174 (51.15%), Query Frame = 1

Query:  412 LSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN---KMVWKSLVALIGIHLFFLTERIT-ILYQNLRSKRKSKKQ 921
            LSW     S ++ + F  LCP+LL Q+ SRVC       +     + N+        L +      AV VIS   LL V  +P++ +  +  + + L+ALAVG+L GDALLHL+PHA  D    G+ H G     + V K L  L G++L FL E +  +L Q  + KR SK +
Sbjct:  189 LSWV----SAITPQQFSLLCPALLYQIDSRVC-------IHHSDELTNSKPDSKQALLQVLGWGALAVTVISAPSLLAVAFVPLLRRPLFRYLLRFLVALAVGTLCGDALLHLMPHAQED--HTGNQHGGKTHAIEPVLKGLSVLGGLYLLFLIENLMGLLKQRQQLKRLSKPE 349

[Close]

BLAST of slc39a-4 vs. Ensembl Xenopus
Match: tmem135 (transmembrane protein 135 [Source:Xenbase;Acc:XB-GENE-954105])

HSP 1 Score: 154.451 bits (389), Expect = 1.229e-38
Identity = 74/158 (46.84%), Postives = 107/158 (67.72%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIG-VQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            +  I + V+ GDG+HNF DG+AIGAAF++   GGLST +AV CHELPHELGDF VLL +G+ +R  +F++L+S+     GM+IG V       I+ WIF  TAG+FLY+ALVDM+P++  R    +    +  ++    ++GF++G AIM  IALY++
Sbjct:  458 ITEIVWMVLLGDGIHNFTDGLAIGAAFSSGFSGGLSTTVAVFCHELPHELGDFAVLLQSGVPVRKVLFFSLVSAFLSFFGMIIGAVASQNSAQITPWIFAATAGIFLYVALVDMLPQMLHRE-TADPCQGKDCVI---HSLGFLLGCAIMFCIALYQD 611

HSP 2 Score: 70.4774 bits (171), Expect = 7.870e-12
Identity = 62/174 (35.63%), Postives = 89/174 (51.15%), Query Frame = 1

Query:  412 LSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN---KMVWKSLVALIGIHLFFLTERIT-ILYQNLRSKRKSKKQ 921
            LSW     S ++ + F  LCP+LL Q+ SRVC       +     + N+        L +      AV VIS   LL V  +P++ +  +  + + L+ALAVG+L GDALLHL+PHA  D    G+ H G     + V K L  L G++L FL E +  +L Q  + KR SK +
Sbjct:  230 LSWV----SAITPQQFSLLCPALLYQIDSRVC-------IHHSDELTNSKPDSKQALLQVLGWGALAVTVISAPSLLAVAFVPLLRRPLFRYLLRFLVALAVGTLCGDALLHLMPHAQED--HTGNQHGGKTHAIEPVLKGLSVLGGLYLLFLIENLMGLLKQRQQLKRLSKPE 390

[Close]

BLAST of slc39a-4 vs. Ensembl Mouse
Match: Slc39a10 (solute carrier family 39 (zinc transporter), member 10 [Source:MGI Symbol;Acc:MGI:1914515])

HSP 1 Score: 182.185 bits (461), Expect = 4.416e-47
Identity = 88/160 (55.00%), Postives = 117/160 (73.12%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + +  IA+ VI GDG+HNF DG+AIGAAF+  + GG+ST+IAV CHELPHELGDF VLL AGM+++ AI YNL+S++   IGM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+        +    P   F+ QN+G + G AIMLVIALYE+
Sbjct:  666 TGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAITAGMFLYVALVDMLPEMLHGDGDHEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 825

HSP 2 Score: 72.7886 bits (177), Expect = 1.594e-12
Identity = 65/214 (30.37%), Postives = 107/214 (50.00%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNL--AIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN------------------------KMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKK 948
            +C +  Q+L  F     S +S + F  LCP+LL Q+ SR+C  +  + +      + T  P    N+  + W+C   ++ VISL+ LL V L+PI+ +  +  +   L+ALAVG+++GDALLHL+P          HS  GH+                          V K LVAL GI+L F+ E    ++++ + +R  K++ F+K  T++
Sbjct:  338 ECLNVTQLLKHFGLGPNSPISPDLFTYLCPALLYQIDSRLCIEHFDKLLVEDLNKDKTLVPEDKTNIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLP----------HSQGGHDHSHQHTHGHGHSHGHESKEFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR-GKQKWFMKQSTEE 540

[Close]

BLAST of slc39a-4 vs. Ensembl Mouse
Match: Slc39a6 (solute carrier family 39 (metal ion transporter), member 6 [Source:MGI Symbol;Acc:MGI:2147279])

HSP 1 Score: 164.466 bits (415), Expect = 1.978e-41
Identity = 79/161 (49.07%), Postives = 111/161 (68.94%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI--LFLWQNIGFVIGSAIMLVIALYE 2106
            + +  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM+++ A+ YN +S++   +GM  G+ +G    ++S WIF LTAG+F+Y+ALVDM+PE+    L  +   H  S    F  QN G ++G  IML+I+++E
Sbjct:  600 AGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEM----LHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFE 756

HSP 2 Score: 61.2326 bits (147), Expect = 5.538e-9
Identity = 56/199 (28.14%), Postives = 90/199 (45.23%), Query Frame = 1

Query:  352 NNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---------------MDDG-------EKGHSHNGHNKMVWKSLVALIGIHLFFLTERITIL 882
            +NI + FN   +     + + +  N T       +F  LCP+++ Q+ +R C  +     K   P    S  +       WL  F A+ +IS + LL V L+P+M + ++  +   L+ALAVG+L+GDALLHL+PH+                M  G        +    + +    WK L AL G++  FL E +  L
Sbjct:  268 DNIQECFNTTKLLTSHGMSIQALLNAT-------EFNYLCPAIINQIDARACLIHTASEKKAEIPPKTYSLQIA------WLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHQHSHSHEEPAMEMKRGPLFSHLSAQNIEESSYFDSTWKGLTALGGLYFMFLVEHVLTL 453

[Close]

BLAST of slc39a-4 vs. Ensembl Mouse
Match: Slc39a12 (solute carrier family 39 (zinc transporter), member 12 [Source:MGI Symbol;Acc:MGI:2139274])

HSP 1 Score: 157.532 bits (397), Expect = 1.283e-39
Identity = 69/158 (43.67%), Postives = 109/158 (68.99%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            ++  +A  ++ GD LHNF DG+ IG AF++ +  G++T IA+LCHE+PHE+GDF VLL +G+S+RTAI  N +S++    G+ IG+ +   P +  WI  +TAGMFLY++LV M+PE++  + +      RP + FL QN+G V+G   +L++A+YE+
Sbjct:  498 TISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQ------RPWMTFLLQNVGLVLGWFSLLLLAVYEQ 649

HSP 2 Score: 72.4034 bits (176), Expect = 1.762e-12
Identity = 63/177 (35.59%), Postives = 91/177 (51.41%), Query Frame = 1

Query:  391 CHSPIQMLSWFNKTKSGLS--KEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---MDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKR 906
            C S  Q++  F +  S LS  KEDF  L P ++ Q++S  C+    Q  KP  P   T      + +A+ L + G+++  +LV            +  Y+ I QL + LAVG+L+GDALLHLIP  L     + E GH H   +  +WK L  L GIH FFL E+  IL  +  +K+
Sbjct:  309 CFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKP-PP--TTLEKYGYSTVAVTLLTLGSMLGTALVLFHSC-------EENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAEFGHFHESQSP-IWKLLGLLGGIHGFFLIEKCFILLVSPNTKK 474

[Close]

BLAST of slc39a-4 vs. Ensembl Mouse
Match: Slc39a12 (solute carrier family 39 (zinc transporter), member 12 [Source:MGI Symbol;Acc:MGI:2139274])

HSP 1 Score: 157.532 bits (397), Expect = 1.782e-39
Identity = 69/158 (43.67%), Postives = 109/158 (68.99%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            ++  +A  ++ GD LHNF DG+ IG AF++ +  G++T IA+LCHE+PHE+GDF VLL +G+S+RTAI  N +S++    G+ IG+ +   P +  WI  +TAGMFLY++LV M+PE++  + +      RP + FL QN+G V+G   +L++A+YE+
Sbjct:  534 TISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQ------RPWMTFLLQNVGLVLGWFSLLLLAVYEQ 685

HSP 2 Score: 72.0182 bits (175), Expect = 2.400e-12
Identity = 62/169 (36.69%), Postives = 87/169 (51.48%), Query Frame = 1

Query:  391 CHSPIQMLSWFNKTKSGLS--KEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---MDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITIL 882
            C S  Q++  F +  S LS  KEDF  L P ++ Q++S  C+    Q  KP  P   T      + +A+ L + G+++  +LV            +  Y+ I QL + LAVG+L+GDALLHLIP  L     + E GH H   +  +WK L  L GIH FFL E+  IL
Sbjct:  309 CFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKP-PP--TTLEKYGYSTVAVTLLTLGSMLGTALVLFHSC-------EENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAEFGHFHESQSP-IWKLLGLLGGIHGFFLIEKCFIL 466

[Close]

BLAST of slc39a-4 vs. Ensembl Mouse
Match: Slc39a14 (solute carrier family 39 (zinc transporter), member 14 [Source:MGI Symbol;Acc:MGI:2384851])

HSP 1 Score: 153.295 bits (386), Expect = 5.164e-39
Identity = 74/159 (46.54%), Postives = 108/159 (67.92%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELS--TRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALY 2103
            S +  +A+ +   DGLHNF DG+AIGA+F   +  G+ST++A+LC E PHELGDFV+LL+AGMS++ A+F+N +S+  C +G+  G+  G   S ++WIF L  GMFLYIAL DM PE++   +  + N  F  P   F+ QN+G + G +IMLV+ +Y
Sbjct:  328 SDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYIALADMFPEMNEVCQEDEKNDSFLVP---FVIQNLGLLTGFSIMLVLTMY 482

HSP 2 Score: 56.225 bits (134), Expect = 1.393e-7
Identity = 44/165 (26.67%), Postives = 77/165 (46.67%), Query Frame = 1

Query:  433 KSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHF 927
            +S +   +F   CP++L Q+ S+ C     +  +  +      S +      +W   F +V +I+L  LL V ++P   K++++ +    IAL++G+L  +AL  LIP A           N  +  V KS V   G +LFF TE+I  +    +++      HF
Sbjct:  104 RSQIGASEFQEFCPTILQQLDSQACTSENQKSEENEQTEEGKPSAI-----EVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAF--------GFNPQDNYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHNHF 255

[Close]

BLAST of slc39a-4 vs. UniProt/SwissProt
Match: sp|Q6PEH9|S39AA_DANRE (Zinc transporter ZIP10 OS=Danio rerio OX=7955 GN=slc39a10 PE=2 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 2.986e-47
Identity = 88/163 (53.99%), Postives = 122/163 (74.85%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEEH 2112
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++    GMVIG  +G+   +++SWIF +TAGMFLY+ALVDM+PE+    L G+   H+   +  F+ QN G + G  IML+IA++E+H
Sbjct:  682 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYAGMVIGTAVGQYTHNVTSWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRCEMGHFVLQNFGMLTGFGIMLLIAIFEDH 840

HSP 2 Score: 73.9442 bits (180), Expect = 4.357e-12
Identity = 60/188 (31.91%), Postives = 95/188 (50.53%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM--------------VWKSLVALIGIHLFFLTERITILYQNLRSKR 906
            +C +  Q+L  +   + S +S   F  LCP+LL Q+  R C  +                 V  ++  +W+  F ++ +ISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+  D     H HN   +M              VWK L AL GI+L F+ E    ++++   +R
Sbjct:  382 ECLNLTQLLHQYGLSSDSLISPVQFTYLCPALLYQIDRRFCILHYHHV--------EAEEQVAPSSGWVWMWGFVSITIISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHSQGD-----HDHNHGEQMEEEPEVDFLIKFDGVWKGLTALAGIYLLFIIEHCIGMFKHYSDQR 556

[Close]

BLAST of slc39a-4 vs. UniProt/SwissProt
Match: sp|Q9VSL7|FOI_DROME (Zinc transporter foi OS=Drosophila melanogaster OX=7227 GN=foi PE=1 SV=3)

HSP 1 Score: 181.415 bits (459), Expect = 1.869e-46
Identity = 82/157 (52.23%), Postives = 114/157 (72.61%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            ++ A+A+ +I GDGLHNF DG+AIGAAFA +I GG ST++AV CHELPHELGDF +L+ AGMS+++A++YNL++ V   IGM+ G+  G+   ++ W+F + AG+F+YIALVDMMPE+S          H+    FL Q +G + G  IML+IALYE
Sbjct:  539 TLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISAS--------HKSLGQFLLQILGMLSGVGIMLLIALYE 687

HSP 2 Score: 73.1738 bits (178), Expect = 6.705e-12
Identity = 59/191 (30.89%), Postives = 94/191 (49.21%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSR---VCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLR---SKRKSKKQHFLKLLTKKLSLENFYSEASAGDKF 996
            LS +D + LCP LL ++ ++      P +   +   + +         +   +W+ +F +V    ++GL+ V +IP M   YY  I Q L+ALAVG++ GDALLHL+PH+L    E+G        M+ K L  L GI  F++ E    +    R    K+++KK    K++    S  N    + AGDK 
Sbjct:  210 LSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKD--KDIFYVWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERG--------MIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRAKVMRDPDSSVN---NSVAGDKI 387

[Close]

BLAST of slc39a-4 vs. UniProt/SwissProt
Match: sp|Q6P5F6|S39AA_MOUSE (Zinc transporter ZIP10 OS=Mus musculus OX=10090 GN=Slc39a10 PE=1 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 3.089e-46
Identity = 88/160 (55.00%), Postives = 117/160 (73.12%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + +  IA+ VI GDG+HNF DG+AIGAAF+  + GG+ST+IAV CHELPHELGDF VLL AGM+++ AI YNL+S++   IGM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+        +    P   F+ QN+G + G AIMLVIALYE+
Sbjct:  666 TGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAITAGMFLYVALVDMLPEMLHGDGDHEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 825

HSP 2 Score: 72.7886 bits (177), Expect = 1.115e-11
Identity = 65/214 (30.37%), Postives = 107/214 (50.00%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNL--AIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN------------------------KMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKK 948
            +C +  Q+L  F     S +S + F  LCP+LL Q+ SR+C  +  + +      + T  P    N+  + W+C   ++ VISL+ LL V L+PI+ +  +  +   L+ALAVG+++GDALLHL+P          HS  GH+                          V K LVAL GI+L F+ E    ++++ + +R  K++ F+K  T++
Sbjct:  338 ECLNVTQLLKHFGLGPNSPISPDLFTYLCPALLYQIDSRLCIEHFDKLLVEDLNKDKTLVPEDKTNIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLP----------HSQGGHDHSHQHTHGHGHSHGHESKEFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR-GKQKWFMKQSTEE 540

[Close]

BLAST of slc39a-4 vs. UniProt/SwissProt
Match: sp|Q9ULF5|S39AA_HUMAN (Zinc transporter ZIP10 OS=Homo sapiens OX=9606 GN=SLC39A10 PE=1 SV=2)

HSP 1 Score: 182.185 bits (461), Expect = 3.190e-46
Identity = 88/160 (55.00%), Postives = 117/160 (73.12%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            + +  IA+ VI GDG+HNF DG+AIGAAF+  + GG+ST+IAV CHELPHELGDF VLL AGM+++ AI YNL+S++   IGM+IG  +G+   +I+ WIF +TAGMFLY+ALVDM+PE+        +    P   F+ QN+G + G AIMLVIALYE+
Sbjct:  664 TGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823

HSP 2 Score: 72.4034 bits (176), Expect = 1.203e-11
Identity = 65/209 (31.10%), Postives = 110/209 (52.63%), Query Frame = 1

Query:  388 KCHSPIQMLSWF-NKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKP--MKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHS-------------HNGHNKM------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKK 948
            +C +  Q+L ++ +   S +S + F  LCP+LL Q+ SR+C  +  + +     K  N       N   + W+C   ++ VISL+ LL V L+PI+ +  +  +   L+ALAVG+++GDALLHL+PH+     + GH               +  NK       V K LVAL GI+L F+ E    ++++ + +R  K++ F+K  T++
Sbjct:  336 ECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHS-----QGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR-GKQKWFMKQNTEE 538

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BLAST of slc39a-4 vs. UniProt/SwissProt
Match: sp|Q4V887|S39A6_RAT (Zinc transporter ZIP6 OS=Rattus norvegicus OX=10116 GN=Slc39a6 PE=1 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 7.330e-41
Identity = 79/161 (49.07%), Postives = 111/161 (68.94%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI--LFLWQNIGFVIGSAIMLVIALYE 2106
            + +  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM+++ A+ YN +S++   +GM  G+ +G    ++S WIF LTAG+F+Y+ALVDM+PE+    L  +   H  S    F  QN G ++G  IML+I+++E
Sbjct:  576 AGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEM----LHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFE 732

HSP 2 Score: 60.8474 bits (146), Expect = 4.264e-8
Identity = 58/203 (28.57%), Postives = 97/203 (47.78%), Query Frame = 1

Query:  343 RKRNNISKTFNNVSIKCHSPIQMLSWFNKT-KSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL---------------MDDG-------EKGHSHNGHNKMVWKSLVALIGIHLFFLTERITIL 882
            RK    S+T N+   +C +  ++L+    + ++ L+  +F  LCP+++ Q+ +R C  +     K   P    S  +       WL  F A+ +IS + LL V L+P+M + ++  +   L+ALAVG+L+GDALLHL+PH+                M  G        +    + +    WK L AL G++  FL E +  L
Sbjct:  233 RKSFMYSRTSNDNIQECFNATKLLTSHGMSVQALLNATEFNYLCPAIINQIDARSCLIHTASEKKAEIPPKTYSLQIA------WLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSAQNLEESSYFDSTWKGLTALGGLYFMFLVEHVLTL 429

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BLAST of slc39a-4 vs. TrEMBL
Match: A0A0H3YJK3 (Slc39a-4 OS=Schmidtea mediterranea OX=79327 GN=slc39a-4 PE=2 SV=1)

HSP 1 Score: 1291.95 bits (3342), Expect = 0.000e+0
Identity = 682/682 (100.00%), Postives = 682/682 (100.00%), Query Frame = 1

Query:   67 MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAVIVISLVGLLVVWLIPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSPQIPPENNPNNVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPHGHHHGHSHDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH
Sbjct:   15 MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAVIVISLVGLLVVWLIPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSPQIPPENNPNNVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPHGHHHGHSHDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 696

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BLAST of slc39a-4 vs. TrEMBL
Match: A0A504YEB0 (Zinc transporter ZIP10 OS=Fasciola gigantica OX=46835 GN=FGIG_04175 PE=4 SV=1)

HSP 1 Score: 377.481 bits (968), Expect = 1.731e-115
Identity = 263/661 (39.79%), Postives = 370/661 (55.98%), Query Frame = 1

Query:  250 VYLNSLKNS---SDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSH---------------NGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKAL---STGKLHWASKSRKYSGSSKELVHASSHIGIDGE----------------VNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNY-LLTDRQLTNISSAQNETSNWSNKEDHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGGA---TVKSSLAHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            +Y N  K++     N+S FL     S    K G    +N S+       +C++  QM+ +F    + L+K  F++L P+++ ++ +  C P+          MN+   P  + +    +    AVIV+   GL+VV L+P+M +S+YN ++Q LIAL+VGSL GDA LHLIPHAL   GE  H H               N H  MV KSLVAL+GI+ FFLTER+TIL QN  S++K K+              + + E   GDK    ++   ++          T K    S+S    G ++E   + + + I                    ++   LCNRP  +P  N+ C D   Y  C T +P      ++G    +S     T   +K V     S P++ LLT   +    +A+ E    +N ED   +   +       +++  TV        ++L+  +        +    HP ++KPHGHHHGHSHDLSSVKAIAYT+IAGDGLHNFCDGIAIGAAFAND+ GGLST+IAVLCHELPHELGDF VLLHAGMS++TA+FYNL+SSV CA G  IG+ LG++ S+ +W+FMLTAGMF+YIALVDMMPEL+T RLKG++  H+P++LFLWQN+G  +G  +ML+I+L+E+
Sbjct:   49 LYANLTKDAFLYPQNLSKFLDHLNISPN--KRGGHLDHNHSQQSEIQEPECYTAEQMVGFF-APAAHLNKSQFVSLLPTIVYELHTHACHPD---------HMNSKIVPANSRDWKAIVACVVAVIVLGSSGLIVVALVPLMSRSFYNVVTQFLIALSVGSLTGDAFLHLIPHAL--SGEHSHGHKSDQMHGHHNEKAEENSHRNMVMKSLVALLGIYAFFLTERLTILCQNRTSRKKMKRL---------AQAAHVFDEDMPGDKTLGYQRVIAQTPYRNGYLHPETSKSAEQSRSDALVGGAQETSKSKNSLQIHARQLSVPEGLSTAHPEPLSHVDNQLCNRPPERPMDNTRCVD---YLKC-TFSP------ADGFTRAHSGTLGPTGSNVKHV---SGSTPHFWLLTSTAIVGTPTARAEG---ANNED-PTMKKTVTSTGIAPSIDNNTVTGDVVTWQKQLQTNSPTVFLNDTEQQPTHPHRDKPHGHHHGHSHDLSSVKAIAYTIIAGDGLHNFCDGIAIGAAFANDLRGGLSTSIAVLCHELPHELGDFAVLLHAGMSVKTALFYNLLSSVLCAAGTAIGLLLGQMESVDAWLFMLTAGMFVYIALVDMMPELTTNRLKGHRYCHQPTVLFLWQNLGIFLGYVVMLLISLFED 669

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BLAST of slc39a-4 vs. TrEMBL
Match: A0A3R7CP08 (Zinc transporter ZIP10 OS=Clonorchis sinensis OX=79923 GN=slc39a10 PE=4 SV=1)

HSP 1 Score: 372.859 bits (956), Expect = 1.511e-114
Identity = 246/609 (40.39%), Postives = 353/609 (57.96%), Query Frame = 1

Query:  388 KCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGH---------SHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHF---LKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYS-----------GSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTD------RQLTNISSAQNETSNWSNKE----DHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGGATVKSS---LAHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            +C+S  QM+ +F  +++ LSK+ F  L P+++ ++ +  C     +     + ++  +  ++ + +++ + S   +IV++L+        P+MP+ ++N ISQ LIAL+VGSL GDA LHLIPHAL  D +  H         +HN H++M+ K+LVAL+GI+ FFLTER+TIL QN  S+RK K+Q       +  K L+          G    ++EK   + S N     G      +SR++            G+   +V+  +   ++ E      LC RP  +P  N+ C D ++ ++   +N  S+ P         +  + Q +G +    P     P   LT        +L   ++A  +TS ++ ++     H +L                   +K   +T   E       + S+     HP ++KPHGHHHGHSHDLSSV+AIAYTVI GDGLHNFCDGIAIGAAF+ +I GGLSTAIAVLCHELPHELGDF VLLHAGMS++ AIFYNL+SS+ CA G VIG+ LG++ SI +WIFMLTAGMF+YIALVDMMPEL+T RLKG++  HRPSILF+WQN+G ++G  IML+IA YE
Sbjct:   38 QCYSAEQMIDFFPNSQT-LSKQQFGELLPTVVYELHTHACHHEHPEHSH-SRALDWKA--IVGSTVSVLVISISGLIVVALI--------PLMPRRFFNVISQFLIALSVGSLTGDAFLHLIPHALAPDHDHTHEEQTTTNVEAHN-HHEMISKALVALLGIYAFFLTERLTILCQNNTSRRKMKRQRASTNEAVGEKDLTYPPLSGAEQNGSLPTETEK---QESTNVMQPVGL-----RSREHGTPNTKPSVDNVGNPTLVVNGVTTSHMENE------LCGRPPDRPLDNARCADHLSGDVFVRVNSASLIP-------GGTHHKDQQDGAVHFCWPSSVYIPPTELTSSERSTATELPTQNAALADTSEFARRQRLEASHDVLDVDNRNGQM----------SKWKQNTTFAESNLAKTYLDSAHEQPTHPHRDKPHGHHHGHSHDLSSVRAIAYTVIVGDGLHNFCDGIAIGAAFSTNINGGLSTAIAVLCHELPHELGDFAVLLHAGMSVKAAIFYNLLSSILCAAGTVIGLLLGRIASIDTWIFMLTAGMFVYIALVDMMPELATNRLKGHRRCHRPSILFIWQNVGILLGYGIMLLIAFYE 602

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BLAST of slc39a-4 vs. TrEMBL
Match: A0A1S8WKI7 (Metal cation transporter, ZIP family OS=Opisthorchis viverrini OX=6198 GN=X801_09260 PE=4 SV=1)

HSP 1 Score: 372.089 bits (954), Expect = 4.098e-112
Identity = 263/684 (38.45%), Postives = 384/684 (56.14%), Query Frame = 1

Query:  232 KTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNI--SKTFNNVSIK--CHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHS---------HNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKA---PV-----KSSENKALSTGKLHWASKS-RKYSGS--------------------SKELVHASSHIGIDGEVN-------IGAH----LCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGG------ATVKSSLAHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            KT IA+ +L +L  S  N +  +  +     +  L L   ++    +  +N +I+  C+S  QM+ +F  +++ L+K+ F  L P+++ ++ +  C    ++     + ++  +  ++ + +++ + S   +IV++L+        P+MP+ ++N ISQ LIAL+VGSL GDA LHLIPHAL  + + GH          HN H++M+ K+LVAL+GI+ FFLTER+TIL QN  S++K K+Q  +      + L   +    +G     SE A   PV     K+S N+A+    L +   S  + +GS                    S+E    ++   +D   N       + +H    LC RP  +P  N+ C D ++ ++   +N  S+ P   G +  N     Q +G +    P     P   LT  +     S   E    +   D   L+ +  PE + + V++     + S   +               T +    HP ++KPHGHHHGHSHDLSSV+AIAYTVI GDGLHNFCDGIAIGAAF+ ++ GGLSTAIAVLCHELPHELGDF VLLHAGMS++ AIFYNL+SS+ CA G VIG+ LG++ SI +WIFMLTAGMF+YIALVDMMPEL+T RLKG +  HRPSILF+WQN+G ++G  IML+IA YE
Sbjct:  134 KTDIAEHHLTALFTSITNGTT-VDQQQLEKFLNGLHLSSPDHAHDEEHVHNETIETHCYSAEQMIEFFPNSQT-LTKQQFGELLPTVVYELHTHACHHEHSEHGH-SRALDWKA--IVGSTVSVLVISISGLIVVALI--------PLMPRRFFNVISQFLIALSVGSLTGDAFLHLIPHALAPEHDHGHEDQTTANVEPHN-HHEMIGKALVALLGIYAFFLTERLTILCQNNTSRQKMKRQRVVSSYHVSVWL---FVHIGSGHGSPTSEPALTFPVAFIFHKASNNEAVGEKDLTYPPISGAEQNGSLPMETEKQESTNVMQPVGLRSREHGTPNTKPSVDSAGNLTLAVNGVTSHMENELCGRPPDRPLDNARCADHLSGDVFVRVNSASLIP--GGAHHKN-----QQDGAVHFCWPSSVYIPPTELTSSE----RSTATELPTQNAVADASELTRRQRPEASYDMVDVDNRNGQISKWKQNATFAESNLAKTYLDTAEEQPTHPHRDKPHGHHHGHSHDLSSVRAIAYTVIVGDGLHNFCDGIAIGAAFSTNVNGGLSTAIAVLCHELPHELGDFAVLLHAGMSVKAAIFYNLLSSILCAAGTVIGLLLGRIASIDTWIFMLTAGMFVYIALVDMMPELATNRLKGQRCCHRPSILFIWQNVGILLGYGIMLLIAFYE 789

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BLAST of slc39a-4 vs. TrEMBL
Match: A0A5J4NNK5 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0012597 PE=4 SV=1)

HSP 1 Score: 363.614 bits (932), Expect = 4.991e-110
Identity = 256/660 (38.79%), Postives = 359/660 (54.39%), Query Frame = 1

Query:  307 EGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALM----DDGEKGHSH-----------NGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVK------------------------------SSENKALSTGKLHWASKSRKYS-----GSSKELVHASSHIGIDGEVNIG-AHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGGATVKSSL---------AHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            E   + +  + L   N+  +   +    C+S  +ML++F   K  L K  F  L P+++  + +  C P   +P+K  K      + ++ + +++ + S   +IV++L+        P+M + +YN +SQ LIAL+VGSL GDA +HLIPHAL      D E  H H           + H +M+ KSLV L+GI+ FFLTER+TIL QN  S++K K+Q    +L    S +   ++    DK    +  P +                              ++E++ + T K    + +R+ S       S +L  + SHI     ++ G +HLCNRP  +P  N+ C D +   L   I      P     N + S+           V P   S      T   LT ++      S  ++    + LS  +   N        TV TKH  +T   +  A  AT ++ +          H  ++KPHGHHHGHSHDLSSV+AIAYTVIAGDGLHNFCDGIAIGAAFAN++ GGLSTAIAVLCHELPHELGDF VLLHAGMS++ A+FYNL+SSV CA G  IG+ LG + SI +W+FMLTAGMF+YIALV+MMPEL+T RLKG++I H+PS+LF WQN+G + G  +ML+IA YE
Sbjct:   60 EELQAFLASIHLTPSNHSHEDHESNETHCYSAKEMLNFFPGAKY-LDKRQFGQLLPTMVYSIRTDACHPE-HEPVKTSKTTVGWQA-IVGSLISVIVISVSGLIVVALL--------PMMSRRFYNVVSQFLIALSVGSLTGDAFVHLIPHALTPNHEHDIETEHDHAHTHVAEAQAAHDHREMITKSLVVLVGIYAFFLTERLTILCQNSTSRKKMKRQRLFSILLLNCSQKFINADGHPTDKDVTYQPIPTQGQLTTDGHFCSEVDKEEHLNTSVTAQATGATNEDRGIPTQKSANNANARRLSVPENVSPSVDLFVSLSHILRLQPLSCGESHLCNRPPERPMDNARCVDHLRDNLYARIVMTDATP-----NRDLSDGPSHFWPSAIFVTPDVGSILVDETTSTGLTKVNGII--ASTLASATSQESLSHALDLPNG------NTVKTKHHTNTVT-DYAAVKATPQAMMYLDVSDQQPTHLHRDKPHGHHHGHSHDLSSVRAIAYTVIAGDGLHNFCDGIAIGAAFANNVRGGLSTAIAVLCHELPHELGDFAVLLHAGMSVKAALFYNLLSSVLCAAGTAIGLFLGHIQSIDTWLFMLTAGMFVYIALVNMMPELTTNRLKGHRICHQPSVLFFWQNVGILFGYGVMLLIAFYE 694

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BLAST of slc39a-4 vs. Ensembl Cavefish
Match: slc39a10 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:103023420])

HSP 1 Score: 187.578 bits (475), Expect = 9.397e-49
Identity = 89/163 (54.60%), Postives = 123/163 (75.46%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEEH 2112
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++    GMVIG  +G+   +++SWIF +TAGMFLY+ALVDM+PE+    L G+   H+   L  F+ QN+G + G  IML+IA++E+H
Sbjct:  710 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYFGMVIGTAVGQYTHNVTSWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRCHLGHFVLQNLGMLTGFGIMLLIAIFEDH 868

HSP 2 Score: 82.4185 bits (202), Expect = 1.149e-15
Identity = 67/194 (34.54%), Postives = 103/194 (53.09%), Query Frame = 1

Query:  388 KCHSPIQMLSWFNKTKSGL-SKEDFITLCPSLLVQMVSRVCRPNVTQ-PMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM----------VWKSLVALIGIHLFFLTERITILYQNLRSK-----RKSKK 918
            +C +  Q+L  +  +   L S   F  LCP+LL Q+ SRVC  +  Q  M+  +P          +++ IW+  F ++ VISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+    G   HSH   N            VWK L AL GI+L F+ E    + ++ + +     R+ K+
Sbjct:  425 ECLNLTQLLQHYGLSPDSLISPAQFTYLCPALLYQIDSRVCIRHYHQVAMEETQP----------HSVWIWVWGFVSITVISLLSLLGVVLVPILNQSCFKYLLTFLVALAVGTLSGDALLHLLPHS---QGGHDHSHGEENAEEMDLLTEFDGVWKGLTALAGIYLLFIIEHCISMVKHYKDQGGSFCRRKKR 605

[Close]

BLAST of slc39a-4 vs. Ensembl Cavefish
Match: ENSAMXT00000020125.2 (zinc transporter ZIP6-like [Source:NCBI gene;Acc:103026967])

HSP 1 Score: 171.014 bits (432), Expect = 9.523e-44
Identity = 82/159 (51.57%), Postives = 111/159 (69.81%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++   +GM+ G+ +G    +++ WIF LTAG+F+Y+ALVDM+PE+           H     F+ QN G ++G  IML+IAL+E
Sbjct:  575 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMSVKQAILYNLLSAMMGYLGMITGILIGHYAENVAMWIFALTAGLFMYVALVDMVPEMLHNNASEAGFSH--CGFFVLQNAGILLGFGIMLLIALFE 731

HSP 2 Score: 77.411 bits (189), Expect = 3.834e-14
Identity = 70/225 (31.11%), Postives = 105/225 (46.67%), Query Frame = 1

Query:  442 LSKEDFITLCPSLLVQMVSRVC----------------RPNVTQPMKPMKPMNNTSSPVINNNLAI-WLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEK-------GHSHNGHN----KMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSE 1032
            LS  DF  LCP+LL+Q+ S+ C                  +            NT +   ++ + I W+  F A+ +ISL+ L+ V LIP+M +  +N +   L+ALAVG+L+GDA LHLIPH+  +            HSH+G      K VW  L AL G+++ FL E    L +  + K+K         + K+  L N   E+      ED +  P+  SE
Sbjct:  273 LSVRDFSFLCPALLLQIDSKSCFMHADNLSDYKNQHHHHSHNHHHHDHHDHHENTDTTQKSSPIQIAWIGGFLAITIISLLALVGVVLIPLMDRVCFNFLLSFLVALAVGTLSGDAFLHLIPHSQGNHKHNHPVNESLEHSHHGEEEDPLKPVWTGLTALGGVYVMFLIEHFLTLAKMYKDKKK---------VQKRADLSNEILESEKVPALEDVDVKPLDDSE 488

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BLAST of slc39a-4 vs. Ensembl Cavefish
Match: slc39a5 (zinc transporter ZIP5-like [Source:NCBI gene;Acc:103022330])

HSP 1 Score: 152.91 bits (385), Expect = 1.309e-38
Identity = 77/160 (48.12%), Postives = 106/160 (66.25%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLG-KLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            S + ++A+ V+ GDG+HN  DG+AIG AF+  + GGLST IAV CHELPHELGD  VLL AG  +R    ++L+S++   +G++ G  +G +    S WI  +TAG+FLY+AL DMMPE+    L G++        FL Q +G +IG AIML IAL+EE
Sbjct:  387 SGLGSVAWMVVMGDGIHNLTDGLAIGVAFSQSLTGGLSTTIAVFCHELPHELGDLAVLLAAGWPVRRLAVFSLLSALLGYVGVLGGTAMGHQWAQHSPWILTVTAGVFLYVALADMMPEM----LHGDRGPLGAVKCFLLQCVGLLIGGAIMLCIALFEE 542

HSP 2 Score: 53.9138 bits (128), Expect = 7.151e-7
Identity = 56/191 (29.32%), Postives = 91/191 (47.64%), Query Frame = 1

Query:  352 NNISKTFNNVSIKCHSPIQMLSWFNKTK-SGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQ 921
            N+++K   ++   C +  Q+L  F   + S ++   F  LCP+LL Q+ S VC  +     +  K        +   +LA+++ S           LL + L P++  S   +    + A+AVG+L GDALLHL+PHA          H  H  +V K L  L G+ L F+ E I ++ Q  +  RK ++Q
Sbjct:  175 NHLTK--KHIHENCLNVTQLLWNFGLGQASHITPAHFTFLCPALLYQIDSGVCLRHTESSTEEAKNGVTFLKALGWASLALFVISL--------PSLLALGLAPLISPSSLRTFLCPMAAMAVGTLCGDALLHLLPHA------SSGPHTDHRDVVLKGLSVLGGLFLLFVLESIIVIRQQYKKSRKKRQQ 349

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BLAST of slc39a-4 vs. Ensembl Cavefish
Match: ENSAMXT00000003334.2 (zinc transporter ZIP8-like [Source:NCBI gene;Acc:103022239])

HSP 1 Score: 148.673 bits (374), Expect = 5.954e-38
Identity = 74/160 (46.25%), Postives = 108/160 (67.50%), Query Frame = 1

Query: 1630 LSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL--PSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALY 2103
            L+SV+ +A+ +   D LHNF DG+AIGA+F   I  G ST+IA++C E PHELGDFV+LL+AGM++  AIF+NL+S++ C IG+V+G+ LG    P+I   IF +  GMFLYIAL DM PE++    + +       + F+ QN G + G AI+ +I ++
Sbjct:  276 LASVRTVAWMITLSDALHNFIDGLAIGASFTVSILTGFSTSIAIVCEEFPHELGDFVILLNAGMTVPQAIFFNLLSAMSCYIGLVLGILLGSTFAPNI---IFAIAGGMFLYIALADMFPEMNAIAKEASTRTRTQLVFFIIQNAGLLSGFAIIFLITMF 432

HSP 2 Score: 51.6026 bits (122), Expect = 2.660e-6
Identity = 57/213 (26.76%), Postives = 101/213 (47.42%), Query Frame = 1

Query:  292 AFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTK-SGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHF 927
              L   G +SL+  +   K+    +T   V  +C S   +L+ +  +  + L++++  T+CP+LL Q +   C P   QP             ++ ++  +W   F AV +I+L  LL + LIP+  K Y+  +    I LA+G+L  +A L LIP AL  D +        +  + K++    G +L F TE+  +L   L+++ +    HF
Sbjct:   35 GLLDHSGVNSLLETITQEKQAEQQQT---VQAQCISGEDILTLYGLSNLTHLNQDNLRTICPALLNQALLPTCTPLAAQPQA-----------LVQDH--VWGYGFLAVTIINLFSLLGLLLIPLTKKPYFPKVLTYFIGLAIGTLFSNAALQLIPEALGFDPKA-------DNYILKAVGIFGGFYLLFFTEK--VLKMVLKTEHEHGHSHF 222

[Close]

BLAST of slc39a-4 vs. Ensembl Cavefish
Match: slc39a5 (zinc transporter ZIP5-like [Source:NCBI gene;Acc:103022330])

HSP 1 Score: 149.828 bits (377), Expect = 7.588e-38
Identity = 77/160 (48.12%), Postives = 106/160 (66.25%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLG-KLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            S + ++A+ V+ GDG+HN  DG+AIG AF+  + GGLST IAV CHELPHELGD  VLL AG  +R    ++L+S++   +G++ G  +G +    S WI  +TAG+FLY+AL DMMPE+    L G++        FL Q +G +IG AIML IAL+EE
Sbjct:  347 SGLGSVAWMVVMGDGIHNLTDGLAIGVAFSQSLTGGLSTTIAVFCHELPHELGDLAVLLAAGWPVRRLAVFSLLSALLGYVGVLGGTAMGHQWAQHSPWILTVTAGVFLYVALADMMPEM----LHGDRGPLGAVKCFLLQCVGLLIGGAIMLCIALFEE 502

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BLAST of slc39a-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000371.1 (pep scaffold:Pmarinus_7.0:GL476519:142118:151022:-1 gene:ENSPMAG00000000332.1 transcript:ENSPMAT00000000371.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 180.259 bits (456), Expect = 4.574e-47
Identity = 89/161 (55.28%), Postives = 119/161 (73.91%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            + V +IA+ VI GDG+HNF DG+AIGAAF++    GLST+IAV CHELPHELGDF VLL AGMS++ AI YNL+S++   +G+VIG  +G+   S+++WIF  TAG+FLY+ALVDM+PE+    +  +  + R    FL QN+G ++G  IMLVIA YEEH
Sbjct:  734 AGVSSIAWMVILGDGVHNFSDGLAIGAAFSDSTSVGLSTSIAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALLGYLGLVIGTAVGQYTHSVTTWIFAATAGIFLYVALVDMLPEMLHCEVDSHS-YGRLGC-FLLQNLGLLMGFGIMLVIARYEEH 892

HSP 2 Score: 84.3445 bits (207), Expect = 6.515e-17
Identity = 60/192 (31.25%), Postives = 101/192 (52.60%), Query Frame = 1

Query:  355 NISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPV-INNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM------------VWKSLVALIGIHLFFLTERITILYQN 891
            N S+ F N  +   S +            ++ E F  LCP++L Q+ S+ C       +K  +P N    P+  ++N+  W   F ++ +IS++ LL V ++P+M + ++  +   L+ALAVG+L+GDALLHL+PH+     +  HSHNGH+              +WK L  L GI+L F+ E +  L+++
Sbjct:  425 NASQLFQNFGLDVDSAV------------INTELFSYLCPAILYQIDSQAC-------LKHPEPPNKIDLPLSTDSNMPAWGWGFLSITIISMLSLLGVAIVPMMNQVFFKYLLTFLVALAVGTLSGDALLHLLPHS-----QNSHSHNGHDDHDHILDSDEHLDGIWKGLTGLGGIYLMFIVEHLLALFKH 592

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BLAST of slc39a-4 vs. Ensembl Sea Lamprey
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:799782])

HSP 1 Score: 141.354 bits (355), Expect = 7.240e-37
Identity = 71/158 (44.94%), Postives = 106/158 (67.09%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELS-TRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALY 2103
            S +  +A+ +   DGLHNF DG+AIGA+F   +  G+ST+IA+LC E PHELGDFV+LL+AGMS++ A+F+N +S+  C +G+V G+  G   +  +WIF L  GMFLYI+L DM PE++   +  G +      + F  QN+G + G +IML++ +Y
Sbjct:  190 SRIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSIAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACSCYLGLVCGIVAGSHFA-HNWIFALAGGMFLYISLADMFPEMNEVSKEDGEE--KNNLVTFGIQNLGLLTGFSIMLLLTIY 344

HSP 2 Score: 51.9878 bits (123), Expect = 3.173e-7
Identity = 29/87 (33.33%), Postives = 42/87 (48.28%), Query Frame = 1

Query:  658 PIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKK 918
            P M K +Y  +    IALA+G+L  +AL  LIP A   D  K       +  V+KS V   G +LFF  E+I  +    + +R   +
Sbjct:   39 PFMRKKFYRRLLMYFIALAIGTLYSNALFQLIPEAFGLDPVK-------DGYVYKSAVVFAGFYLFFFAEKILKMVLKQKDERPPNR 118

[Close]

BLAST of slc39a-4 vs. Ensembl Sea Lamprey
Match: SLC39A12 (solute carrier family 39 member 12 [Source:HGNC Symbol;Acc:HGNC:20860])

HSP 1 Score: 127.872 bits (320), Expect = 5.147e-32
Identity = 65/161 (40.37%), Postives = 105/161 (65.22%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHEL---GDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            + ++A  ++ GD +HNF DG+A+GAAF+     GL+T++A+  HE+PHE+   GDF  LL++GM +  A+  N +SS+    G+ +G+ L     +  WIF +TAGMF YI+LVD+MPEL    +K    F  P ++F  QN+G + G +IM+++A++E+ 
Sbjct:  233 MSSLAIMILVGDSIHNFADGLAMGAAFSASNRAGLTTSLAIFFHEVPHEIERSGDFAALLNSGMRVCPALVLNFISSLTAFTGLYVGLSLSNDTIVQQWIFSVTAGMFYYISLVDLMPEL----MKVTGKF--PWVVFALQNVGLLAGWSIMVLLAVFEDQ 387

HSP 2 Score: 69.707 bits (169), Expect = 8.312e-13
Identity = 49/167 (29.34%), Postives = 82/167 (49.10%), Query Frame = 1

Query:  391 CHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHAL-MDDGEKGHSHNGH-----NKMVWKSLVALIGIHLFFLTERI 873
            C+S  ++   F    SG+++ +F  L  +++ Q++S  C  +  +          T        LA+ + S  +++ ++++ +          +  Y  I Q  IALAVG+L+GDA LHLIP  L + D   GH+H        N  VWK +  L GI++FFL E+I
Sbjct:    1 CYSAHELFDVFEFNSSGVARRNFSALAVAIVQQLLSGACWVHGDEEATAPGAAPTTVEKYGYGTLAVLVVSLSSLMGVAVILVTSC-------QETYRVILQTFIALAVGTLSGDATLHLIPTMLVLHDHSDGHNHAEEDFVEKNSHVWKLMALLGGIYMFFLVEKI 160

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BLAST of slc39a-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009266.1 (pep scaffold:Pmarinus_7.0:GL483721:1641:4019:1 gene:ENSPMAG00000008381.1 transcript:ENSPMAT00000009266.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 106.686 bits (265), Expect = 4.335e-27
Identity = 66/152 (43.42%), Postives = 98/152 (64.47%), Query Frame = 1

Query: 1660 VIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFH--RPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            V+ GDGLHNF DG+A+GAAF+  +  GL+T +AV  HELPHE+  F +LL+ G+S++ A+  NL+S++   IG  IG  + +  +   WI     GMFLY+++ +M+ E+        K FH  RP +L L QN+G  +G A ML++ALYE+
Sbjct:    2 VLIGDGLHNFADGLALGAAFSLSLSDGLATMLAVALHELPHEIDIFSILLNTGLSIQAALGLNLLSALTALIGFYIGASVSENETAMQWIIAFATGMFLYLSINNMISEM--------KRFHVDRPWLLLLLQNLGLFLGWAFMLLLALYED 145

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BLAST of slc39a-4 vs. Ensembl Yeast
Match: YKE4 (Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family [Source:SGD;Acc:S000001285])

HSP 1 Score: 67.3958 bits (163), Expect = 2.671e-12
Identity = 48/164 (29.27%), Postives = 83/164 (50.61%), Query Frame = 1

Query: 1660 VIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKL-----------PSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKI--FHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            VI+G   H+  DGIA+  +F +    G+ T+IAV  HE+PHELGDF +LL +G +   AI    +++    +G  IG  + ++            + S  +   TAG  +YIA   ++P++       +K+  F + ++  ++  +GF        V+AL +EH
Sbjct:  191 VISGIA-HHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKATSSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLREFKKWALQLVFIFVGFA-------VMALMDEH 346

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BLAST of slc39a-4 vs. Ensembl Nematostella
Match: EDO37361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG18])

HSP 1 Score: 153.295 bits (386), Expect = 4.308e-43
Identity = 70/152 (46.05%), Postives = 102/152 (67.11%), Query Frame = 1

Query: 1660 VIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI-LFLWQNIGFVIGSAIMLVIALYEEH 2112
            V+ GD +HNF DG+AIGAAF+N I  G ST++A+ C E+PHELGDF VLL  GM++R A+ +N +S+  C +GM IG+ LG       WI+ L  GMF+YIALV M+PE++   ++  +   R ++ +F  QN+G + G  IM V+A+Y+  
Sbjct:    2 VLLGDSMHNFLDGLAIGAAFSNSIIEGFSTSLAIFCEEVPHELGDFAVLLSGGMTVRQALGFNFLSACVCFVGMAIGLLLGYTTHAVKWIYALAGGMFVYIALVAMLPEVNQMSMRAGQGSVRKNLKVFAMQNVGMICGFIIMFVLAMYQSQ 153

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BLAST of slc39a-4 vs. Ensembl Nematostella
Match: EDO29311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T403])

HSP 1 Score: 146.362 bits (368), Expect = 1.392e-40
Identity = 75/156 (48.08%), Postives = 106/156 (67.95%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLK-GNKIFHRPSILFLWQNIGFVIGSAIMLVIALY 2103
            VK IA+T++ GD +HNF DG+AIGAAF++ +  G+STA+A++  E+PHELGDF VLL +GM  R A+ +NL+S V C  G+V+G+ L    +   WI+ + AGMFLYI+LVDM+PE +    K G          F  QN G ++G +IMLV+A+Y
Sbjct:    2 VKPIAWTIVIGDCVHNFIDGVAIGAAFSSSVVEGISTALAIIGEEVPHELGDFAVLLSSGMKYRHAVLFNLLSGVICYTGLVLGLLLAYATASVQWIYAIAAGMFLYISLVDMLPEANEMSCKEGEHSVWSNLKTFALQNSGMLVGFSIMLVLAIY 157

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BLAST of slc39a-4 vs. Ensembl Nematostella
Match: EDO47899 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLA9])

HSP 1 Score: 148.288 bits (373), Expect = 7.931e-40
Identity = 76/156 (48.72%), Postives = 108/156 (69.23%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI-LFLWQNIGFVIGSAIMLVIALY 2103
            VK IA+T++ GD +HNF DG+AIGAAF++ +  G+STA+A+L  E+PHELGDF VLL +GM  R A+ +NL+S V C  G+V+G+ L    +   WI+ + AGMFLYI+LVDM+PE +    K  K     ++  F  QN G ++G +IMLV+A+Y
Sbjct:  116 VKPIAWTIVIGDCVHNFIDGVAIGAAFSSSVVEGISTALAILGEEVPHELGDFAVLLSSGMKYRHAVLFNLLSGVICYTGLVLGLLLAYATASVQWIYAIAAGMFLYISLVDMLPEANEMSCKEGKHSVWSNLKTFALQNSGMLVGFSIMLVLAIY 271

[Close]

BLAST of slc39a-4 vs. Ensembl Nematostella
Match: EDO49001 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHM0])

HSP 1 Score: 142.51 bits (358), Expect = 2.747e-39
Identity = 75/160 (46.88%), Postives = 103/160 (64.38%), Query Frame = 1

Query: 1660 VIAGDGLHNFCDGIAIGAAFANDIGGGLSTAI----AVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSI------LFLWQNIGFVIGSAIMLVIALYEE 2109
            +I GD +HN  DG+AIGAAF+     G+S  I    AV CHELPHELGDF VLL AGMS++ A+  NL+S+  C +G++IG+ +G+   +  WIF +  GMF+Y+ALVDM+P+L           H  S+       FL QNIG + G A+ML+IA++EE
Sbjct:    2 IIIGDTIHNISDGLAIGAAFSEGGSSGISGGISTSIAVFCHELPHELGDFAVLLTAGMSVKMALLANLLSACSCYLGLIIGIVIGQQMEVRLWIFAVAGGMFIYVALVDMLPDL----------MHSESLQTDTWKTFLLQNIGILTGFALMLIIAVFEE 151

[Close]

BLAST of slc39a-4 vs. Ensembl Nematostella
Match: EDO47900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLB0])

HSP 1 Score: 135.191 bits (339), Expect = 1.052e-36
Identity = 68/153 (44.44%), Postives = 103/153 (67.32%), Query Frame = 1

Query: 1648 IAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLK-GNKIFHRPSILFLWQNIGFVIGSAIMLVIALY 2103
            + + ++ GD LHNF DG+AIGA +++ I  G STA+A+ C ELPHELGDF VLL+ GM+ + A+F+N +S+  C +G+V+G+ LG       WI+ L AGMF+YI+LV+M+ E +   +K G     +    F  QN+G +IG A+M ++A+Y
Sbjct:    4 VCWMIVLGDALHNFIDGLAIGAGYSSSILEGASTALAIFCEELPHELGDFAVLLNGGMTYKQAMFFNFISACTCFLGLVMGLLLGYATPAVKWIYALAAGMFIYISLVNMLQEATEMSVKEGEGSIKKNLKTFALQNVGMIIGFAVMFILAIY 156

[Close]

BLAST of slc39a-4 vs. Ensembl Medaka
Match: ENSORLT00000032294.1 (zinc transporter ZIP10 [Source:NCBI gene;Acc:101174784])

HSP 1 Score: 186.422 bits (472), Expect = 1.396e-48
Identity = 87/162 (53.70%), Postives = 125/162 (77.16%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEE 2109
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++   +GM+IG  +G+   ++++WIF +TAGMFLY+ALVDM+PE+    L G+   H+ S L  FL QN+G + G ++ML+IA++E+
Sbjct:  648 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYVGMIIGAAVGQYTHNVTNWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRSHLGHFLLQNLGLLTGFSLMLLIAIFED 805

HSP 2 Score: 95.5153 bits (236), Expect = 1.131e-19
Identity = 70/199 (35.18%), Postives = 111/199 (55.78%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM---------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLS 954
            +C +  Q+LS++     S +S   F  LCP+LL Q+ SRVC  +  Q     KP+N+         + +W+C F ++ VISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+    G+  HS +G  +          VWK L AL GI+L F+ E    ++++ + ++   K      + +KLS
Sbjct:  365 ECLNLTQLLSYYGLNPHSLISPSQFTYLCPALLYQIDSRVCIQHYHQMEVEQKPVNS---------VWVWVCGFVSITVISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHS---QGQHDHSQHGAKEATDLVTDFDGVWKGLTALAGIYLLFIIEHCIAMFKHHKDQKSLGKTSEEGHIGRKLS 551

[Close]

BLAST of slc39a-4 vs. Ensembl Medaka
Match: ENSORLT00000011005.2 (zinc transporter ZIP10 [Source:NCBI gene;Acc:101174784])

HSP 1 Score: 186.422 bits (472), Expect = 1.563e-48
Identity = 87/162 (53.70%), Postives = 125/162 (77.16%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEE 2109
            + + +IA+ VI GDG+HNF DG+AIGAAF+ +I GG+ST++AV CHELPHELGDF VLL AGMS++ AI YNL+S++   +GM+IG  +G+   ++++WIF +TAGMFLY+ALVDM+PE+    L G+   H+ S L  FL QN+G + G ++ML+IA++E+
Sbjct:  657 AGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYVGMIIGAAVGQYTHNVTNWIFAVTAGMFLYVALVDMLPEM----LHGDSEEHKRSHLGHFLLQNLGLLTGFSLMLLIAIFED 814

HSP 2 Score: 95.5153 bits (236), Expect = 1.076e-19
Identity = 70/199 (35.18%), Postives = 111/199 (55.78%), Query Frame = 1

Query:  388 KCHSPIQMLSWFN-KTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM---------VWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLS 954
            +C +  Q+LS++     S +S   F  LCP+LL Q+ SRVC  +  Q     KP+N+         + +W+C F ++ VISL+ LL V L+PI+ +S +  +   L+ALAVG+L+GDALLHL+PH+    G+  HS +G  +          VWK L AL GI+L F+ E    ++++ + ++   K      + +KLS
Sbjct:  374 ECLNLTQLLSYYGLNPHSLISPSQFTYLCPALLYQIDSRVCIQHYHQMEVEQKPVNS---------VWVWVCGFVSITVISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHS---QGQHDHSQHGAKEATDLVTDFDGVWKGLTALAGIYLLFIIEHCIAMFKHHKDQKSLGKTSEEGHIGRKLS 560

[Close]

BLAST of slc39a-4 vs. Ensembl Medaka
Match: slc39a6 (solute carrier family 39 member 6 [Source:NCBI gene;Acc:101164750])

HSP 1 Score: 171.4 bits (433), Expect = 5.857e-44
Identity = 84/159 (52.83%), Postives = 111/159 (69.81%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM++R AI YN++S++   +GMV G+ +G    +I  WIF LTAG+FLY+ALVDM+PE+       +   H     FL QN G ++G  IML+IA++E
Sbjct:  538 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVRQAILYNVLSAMMGYLGMVTGIVIGHYAENICMWIFALTAGLFLYVALVDMVPEMLHNDASDHGFSH--CGFFLLQNAGILLGFCIMLLIAVFE 694

HSP 2 Score: 69.707 bits (169), Expect = 9.755e-12
Identity = 63/195 (32.31%), Postives = 95/195 (48.72%), Query Frame = 1

Query:  382 SIKCHSPIQMLSWFNKTKS-GLSKEDFITLCPSLLVQMVSRVC-RPNVTQPMKPMKPM--------NNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM------------------VWKSLVALIGIHLFFLTERITIL 882
            S +C +   +L++   ++  G++  DF  LCP+LL QM S  C R    Q                NN +     N    W   F ++ +ISL+ LL V LIP+M + ++  +   L+ALAVG+L+GDA LHLIPH+     + GH+H+ H ++                  VWK L AL G+++ FL E    L
Sbjct:  203 STECLNASSILTYHGMSQEVGVTLVDFSYLCPALLNQMDSGACIRHKDHQNHSHGHHGNHNHSDHSNNRTGDDSKNITMAWAGGFLSITIISLLSLLGVVLIPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLIPHS-----QAGHNHH-HQEVGLNPEPHLHLHEEENLDGVWKGLTALGGVYVMFLIEHFLTL 391

[Close]

BLAST of slc39a-4 vs. Ensembl Medaka
Match: slc39a6 (solute carrier family 39 member 6 [Source:NCBI gene;Acc:101164750])

HSP 1 Score: 170.629 bits (431), Expect = 8.517e-44
Identity = 84/159 (52.83%), Postives = 111/159 (69.81%), Query Frame = 1

Query: 1633 SSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLP-SISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            + V  +A+ VI GDGLHNF DG+AIGAAF   +  GLST++AV CHELPHELGDF VLL AGM++R AI YN++S++   +GMV G+ +G    +I  WIF LTAG+FLY+ALVDM+PE+       +   H     FL QN G ++G  IML+IA++E
Sbjct:  534 AGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVRQAILYNVLSAMMGYLGMVTGIVIGHYAENICMWIFALTAGLFLYVALVDMVPEMLHNDASDHGFSH--CGFFLLQNAGILLGFCIMLLIAVFE 690

HSP 2 Score: 72.4034 bits (176), Expect = 1.294e-12
Identity = 62/175 (35.43%), Postives = 90/175 (51.43%), Query Frame = 1

Query:  430 TKSGLSKE------DFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKM------------------VWKSLVALIGIHLFFLTERITIL 882
            T  G+S+E      DF  LCP+LL QM S  C  +   P     P  +T + V  +    W   F ++ +ISL+ LL V LIP+M + ++  +   L+ALAVG+L+GDA LHLIPH+     + GH+H+ H ++                  VWK L AL G+++ FL E    L
Sbjct:  223 TYHGMSQEVGVTLVDFSYLCPALLNQMDSGACIRHKGDP----PPHTHTKTTVCVS----WAGGFLSITIISLLSLLGVVLIPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLIPHS-----QAGHNHH-HQEVGLNPEPHLHLHEEENLDGVWKGLTALGGVYVMFLIEHFLTL 383

[Close]

BLAST of slc39a-4 vs. Ensembl Medaka
Match: SLC39A12 (solute carrier family 39 member 12 [Source:NCBI gene;Acc:101161276])

HSP 1 Score: 157.532 bits (397), Expect = 2.673e-40
Identity = 71/156 (45.51%), Postives = 111/156 (71.15%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYE 2106
            V  +A  VI GD LHNF DG+A+GAAF++ +  G++  +A+LCHE+PHE+GDF VLL +G+S++TA+  N +S++   +G+ IG+ +     +  WIF +TAG+FLY++LV+M+PE+S  R+K +    RP ++FL QN+G  +G A +  IAL+E
Sbjct:  381 VSLLAVMVIVGDSLHNFADGLAVGAAFSSSVETGMAITVAILCHEIPHEMGDFAVLLSSGLSVKTAVLMNFLSALTAFMGLFIGLLVSSENEVQQWIFSITAGIFLYLSLVEMLPEMS--RVKSD----RPCLMFLLQNLGLWMGWACLFFIALFE 530

HSP 2 Score: 53.9138 bits (128), Expect = 5.483e-7
Identity = 30/72 (41.67%), Postives = 42/72 (58.33%), Query Frame = 1

Query:  670 KSYYNSISQLLIALAVGSLAGDALLHLIPHAL-MDDGEKGHSHNGH---NKMVWKSLVALIGIHLFFLTERI 873
            K  Y  + QL + LAVG+L+G+ALLHLIP  L + D    H    H    + +WK L  + GI+ FFL E++
Sbjct:  280 KETYALVLQLFVGLAVGTLSGEALLHLIPQILGLHDDLHSHGDGQHVNEKEYLWKVLGLIAGIYGFFLIEKM 351

[Close]

BLAST of slc39a-4 vs. Planmine SMEST
Match: SMESG000026205.1 (SMESG000026205.1)

HSP 1 Score: 1290.4 bits (3338), Expect = 0.000e+0
Identity = 674/682 (98.83%), Postives = 674/682 (98.83%), Query Frame = 1

Query:   67 MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQHFLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSXXXXXXXXXXXVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPXXXXXXXXXDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 2112
            MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAVIVISLVGLLVVWLIPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQH        LSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSPQIPPENNPNNVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPHGHHHGHSHDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH
Sbjct:    1 MISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQTFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSLILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAVIVISLVGLLVVWLIPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQH--------LSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASKSRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNYELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTDRQLTNISSAQNETSNWSNKEDHKLLSPQIPPENNPNNVEIKTVGTKHSDHTERLEIGAGGATVKSSLAHPFKNKPHGHHHGHSHDLSSVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEH 674

[Close]

BLAST of slc39a-4 vs. Planmine SMEST
Match: SMESG000050464.1 (SMESG000050464.1)

HSP 1 Score: 197.593 bits (501), Expect = 3.455e-54
Identity = 94/160 (58.75%), Postives = 120/160 (75.00%), Query Frame = 1

Query: 1636 SVKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLK--GNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            S+ A+A+ VI GDGLHNF DG+AIGAAF   I GG+STA+AV CHELPHELGDF VLL  GM ++ A+FYN++SSV C +GMVIG+ L  + S S WIF +TAG F+YIALVDM+PEL++  ++   ++I H     FL QN+G + G  IML+IALYEE
Sbjct:  369 SIAAVAWMVILGDGLHNFSDGLAIGAAFGVQISGGISTAVAVFCHELPHELGDFAVLLKTGMKVKQALFYNIVSSVLCFLGMVIGIALQSVESASYWIFAITAGTFVYIALVDMLPELNSAEVRPGESRIVH-----FLIQNLGLLTGVGIMLLIALYEE 523

HSP 2 Score: 70.4774 bits (171), Expect = 3.152e-12
Identity = 45/100 (45.00%), Postives = 64/100 (64.00%), Query Frame = 1

Query:  577 NNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGE--KGHSHNGHNKMVWKSLVALIGIHLFFLTER 870
             +L +W+ S  +V +IS VGLL V ++P++ K +YN I Q L+ALAVGSL GDA LHLIPHA++   +  +          V K LVAL G++ FF+ E+
Sbjct:   56 RSLKVWIASTISVFIISAVGLLGVAVVPLVQKVFYNKIIQYLVALAVGSLTGDAFLHLIPHAILGQVQIPEEQKEKEEYTAVLKGLVALGGVYFFFMAEK 155

[Close]

BLAST of slc39a-4 vs. Planmine SMEST
Match: SMESG000016243.1 (SMESG000016243.1)

HSP 1 Score: 156.377 bits (394), Expect = 1.173e-40
Identity = 77/160 (48.12%), Postives = 115/160 (71.88%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPEL-STRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEE 2109
            V  +A+ +I GD LHNF DG++IGAAF+++   G+S +IAV+C ELPHELGDF +LL+AGM+++ A+ +N++S+  C IG +IGV LG+  S S+W+F +  GMFLYI+LVDMM E+ +T   K +       I   F+ QNIG ++G +I+L++ALY +
Sbjct:  290 VAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYISLVDMMSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGD 449

HSP 2 Score: 58.9214 bits (141), Expect = 9.525e-9
Identity = 64/209 (30.62%), Postives = 97/209 (46.41%), Query Frame = 1

Query:  268 KNSSDNMSAFLSSEGFSSLILKLGLRK-----RNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRP--NVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN-KMVWKSLVALIGIHLFFLTER 870
            K+S DN       + F +L L   L+      +N +SK   N S +C     +   F  +   L K  F      L+  +V +V  P  N+ +   P     N SS      + +W+  F +V +I+    L +  IP+M K +Y  +   +I+LAVGSL G ALL LIP A M   E  H + G+     +K+ V   G+++FFL ER
Sbjct:   16 KSSYDNFV-----DLFGNLFLNFSLQNAGDLMKNKLSKA--NFSTEC-----LARRFVNSTPELQKSTF----EGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSS------VKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDA-MQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLER 201

[Close]

BLAST of slc39a-4 vs. Planmine SMEST
Match: SMESG000016243.1 (SMESG000016243.1)

HSP 1 Score: 155.992 bits (393), Expect = 2.476e-40
Identity = 77/160 (48.12%), Postives = 115/160 (71.88%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPEL-STRRLKGNKIFHRPSIL--FLWQNIGFVIGSAIMLVIALYEE 2109
            V  +A+ +I GD LHNF DG++IGAAF+++   G+S +IAV+C ELPHELGDF +LL+AGM+++ A+ +N++S+  C IG +IGV LG+  S S+W+F +  GMFLYI+LVDMM E+ +T   K +       I   F+ QNIG ++G +I+L++ALY +
Sbjct:  307 VAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYISLVDMMSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGD 466

HSP 2 Score: 58.9214 bits (141), Expect = 1.024e-8
Identity = 64/209 (30.62%), Postives = 97/209 (46.41%), Query Frame = 1

Query:  268 KNSSDNMSAFLSSEGFSSLILKLGLRK-----RNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCPSLLVQMVSRVCRP--NVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAXXXXXXXXXXXXXXXPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHN-KMVWKSLVALIGIHLFFLTER 870
            K+S DN       + F +L L   L+      +N +SK   N S +C     +   F  +   L K  F      L+  +V +V  P  N+ +   P     N SS      + +W+  F +V +I+    L +  IP+M K +Y  +   +I+LAVGSL G ALL LIP A M   E  H + G+     +K+ V   G+++FFL ER
Sbjct:   33 KSSYDNFV-----DLFGNLFLNFSLQNAGDLMKNKLSKA--NFSTEC-----LARRFVNSTPELQKSTF----EGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSS------VKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDA-MQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLER 218

[Close]

BLAST of slc39a-4 vs. Planmine SMEST
Match: SMESG000016191.1 (SMESG000016191.1)

HSP 1 Score: 154.066 bits (388), Expect = 7.628e-40
Identity = 73/157 (46.50%), Postives = 104/157 (66.24%), Query Frame = 1

Query: 1639 VKAIAYTVIAGDGLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMSLRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVDMMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEE 2109
            +  +A+ V+ GD LHN  DG++IGA F+  +  G+S ++AVLC ELPHELGDF VLL AGMS++ A+F+NLMS++ C +G +IGV +G + S S WIF    GMFLYI+LVDMM  +          +   ++ F  QN+G   G A +LV++LY +
Sbjct:  295 IAPVAWMVVFGDSLHNLVDGMSIGAGFSQSVILGVSISLAVLCEELPHELGDFAVLLTAGMSVKQAVFWNLMSAMTCYLGFIIGVIVGDITSASVWIFAFAGGMFLYISLVDMMNNIIETIDDMIASWKHKALTFALQNLGLFTGYATILVLSLYSD 451

HSP 2 Score: 58.9214 bits (141), Expect = 9.508e-9
Identity = 27/72 (37.50%), Postives = 45/72 (62.50%), Query Frame = 1

Query:  658 PIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDDGEKGHSHNGHNKMVWKSLVALIGIHLFFLTERI 873
            P+M K  YNS+   +++LA+G+LAG ++L LIP ++        + +  N   WK+   + G++LFFLTER+
Sbjct:  145 PLMKKKIYNSVMTFMVSLAIGALAGTSILILIPDSMQISEIALKAKHDKNDYKWKATGVVAGLYLFFLTERL 216

The following BLAST results are available for this feature:

BLAST of slc39a-4 vs. Ensembl Human
BLAST of slc39a-4 vs. Ensembl Celegans
BLAST of slc39a-4 vs. Ensembl Fly
BLAST of slc39a-4 vs. Ensembl Zebrafish
BLAST of slc39a-4 vs. Ensembl Xenopus
BLAST of slc39a-4 vs. Ensembl Mouse
BLAST of slc39a-4 vs. UniProt/SwissProt
BLAST of slc39a-4 vs. TrEMBL
BLAST of slc39a-4 vs. Ensembl Cavefish
BLAST of slc39a-4 vs. Ensembl Sea Lamprey
BLAST of slc39a-4 vs. Ensembl Yeast
BLAST of slc39a-4 vs. Ensembl Nematostella
BLAST of slc39a-4 vs. Ensembl Medaka
BLAST of slc39a-4 vs. Planmine SMEST

BLAST of slc39a-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC39A10	6.643e-47	55.00	solute carrier family 39 member 10 [Source:HGNC Sy...	[more]
SLC39A10	6.643e-47	55.00	solute carrier family 39 member 10 [Source:HGNC Sy...	[more]
SLC39A6	2.190e-41	49.69	solute carrier family 39 member 6 [Source:HGNC Sym...	[more]
SLC39A6	2.190e-41	49.69	solute carrier family 39 member 6 [Source:HGNC Sym...	[more]
SLC39A12	9.872e-39	44.94	solute carrier family 39 member 12 [Source:HGNC Sy...	[more]

BLAST of slc39a-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zipt-15	2.363e-39	45.96	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-15	1.584e-38	45.96	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-17	6.786e-28	39.38	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-16	1.551e-20	33.76	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-16	1.551e-20	33.76	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]

BLAST of slc39a-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foi	1.864e-47	52.23	gene:FBgn0024236 transcript:FBtr0331418	[more]
foi	1.864e-47	52.23	gene:FBgn0024236 transcript:FBtr0345601	[more]
foi	1.864e-47	52.23	gene:FBgn0024236 transcript:FBtr0331417	[more]
foi	1.864e-47	52.23	gene:FBgn0024236 transcript:FBtr0076624	[more]
Zip71B	2.512e-35	46.54	gene:FBgn0036461 transcript:FBtr0113171	[more]

BLAST of slc39a-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc39a10	4.066e-48	53.99	solute carrier family 39 member 10 [Source:NCBI ge...	[more]
slc39a10	7.557e-48	53.99	solute carrier family 39 member 10 [Source:NCBI ge...	[more]
slc39a6	3.985e-45	51.88	solute carrier family 39 member 6 [Source:ZFIN;Acc...	[more]
BX119991.1	2.201e-38	48.45	solute carrier family 39 member 5 [Source:NCBI gen...	[more]
slc39a5	2.755e-38	48.45	solute carrier family 39 member 5 [Source:ZFIN;Acc...	[more]

BLAST of slc39a-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000051316.1	1.235e-46	52.50	solute carrier family 39 member 10 [Source:NCBI ge...	[more]
ENSXETT00000051324.1	1.351e-46	52.50	solute carrier family 39 member 10 [Source:NCBI ge...	[more]
rabl6	2.333e-42	45.70	RAB, member RAS oncogene family like 6 [Source:Xen...	[more]
tmem135	8.592e-39	46.84	transmembrane protein 135 [Source:Xenbase;Acc:XB-G...	[more]
tmem135	1.229e-38	46.84	transmembrane protein 135 [Source:Xenbase;Acc:XB-G...	[more]

BLAST of slc39a-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc39a10	4.416e-47	55.00	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a6	1.978e-41	49.07	solute carrier family 39 (metal ion transporter), ...	[more]
Slc39a12	1.283e-39	43.67	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a12	1.782e-39	43.67	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a14	5.164e-39	46.54	solute carrier family 39 (zinc transporter), membe...	[more]

BLAST of slc39a-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6PEH9\|S39AA_DANRE	2.986e-47	53.99	Zinc transporter ZIP10 OS=Danio rerio OX=7955 GN=s...	[more]
sp\|Q9VSL7\|FOI_DROME	1.869e-46	52.23	Zinc transporter foi OS=Drosophila melanogaster OX...	[more]
sp\|Q6P5F6\|S39AA_MOUSE	3.089e-46	55.00	Zinc transporter ZIP10 OS=Mus musculus OX=10090 GN...	[more]
sp\|Q9ULF5\|S39AA_HUMAN	3.190e-46	55.00	Zinc transporter ZIP10 OS=Homo sapiens OX=9606 GN=...	[more]
sp\|Q4V887\|S39A6_RAT	7.330e-41	49.07	Zinc transporter ZIP6 OS=Rattus norvegicus OX=1011...	[more]

BLAST of slc39a-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YJK3	0.000e+0	100.00	Slc39a-4 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A504YEB0	1.731e-115	39.79	Zinc transporter ZIP10 OS=Fasciola gigantica OX=46...	[more]
A0A3R7CP08	1.511e-114	40.39	Zinc transporter ZIP10 OS=Clonorchis sinensis OX=7...	[more]
A0A1S8WKI7	4.098e-112	38.45	Metal cation transporter, ZIP family OS=Opisthorch...	[more]
A0A5J4NNK5	4.991e-110	38.79	Uncharacterized protein OS=Paragonimus westermani ...	[more]

BLAST of slc39a-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc39a10	9.397e-49	54.60	solute carrier family 39 member 10 [Source:NCBI ge...	[more]
ENSAMXT00000020125.2	9.523e-44	51.57	zinc transporter ZIP6-like [Source:NCBI gene;Acc:1...	[more]
slc39a5	1.309e-38	48.13	zinc transporter ZIP5-like [Source:NCBI gene;Acc:1...	[more]
ENSAMXT00000003334.2	5.954e-38	46.25	zinc transporter ZIP8-like [Source:NCBI gene;Acc:1...	[more]
slc39a5	7.588e-38	48.13	zinc transporter ZIP5-like [Source:NCBI gene;Acc:1...	[more]

BLAST of slc39a-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSPMAT00000000371.1	4.574e-47	55.28	pep scaffold:Pmarinus_7.0:GL476519:142118:151022:-...	[more]
slc39a14	7.240e-37	44.94	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
SLC39A12	5.147e-32	40.37	solute carrier family 39 member 12 [Source:HGNC Sy...	[more]
ENSPMAT00000009266.1	4.335e-27	43.42	pep scaffold:Pmarinus_7.0:GL483721:1641:4019:1 gen...	[more]

BLAST of slc39a-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
YKE4	2.671e-12	29.27	Zinc transporter; localizes to the ER; null mutant...	[more]

BLAST of slc39a-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37361	4.308e-43	46.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29311	1.392e-40	48.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47899	7.931e-40	48.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49001	2.747e-39	46.88	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47900	1.052e-36	44.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc39a-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000032294.1	1.396e-48	53.70	zinc transporter ZIP10 [Source:NCBI gene;Acc:10117...	[more]
ENSORLT00000011005.2	1.563e-48	53.70	zinc transporter ZIP10 [Source:NCBI gene;Acc:10117...	[more]
slc39a6	5.857e-44	52.83	solute carrier family 39 member 6 [Source:NCBI gen...	[more]
slc39a6	8.517e-44	52.83	solute carrier family 39 member 6 [Source:NCBI gen...	[more]
SLC39A12	2.673e-40	45.51	solute carrier family 39 member 12 [Source:NCBI ge...	[more]

BLAST of slc39a-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000026205.1	0.000e+0	98.83	SMESG000026205.1	[more]
SMESG000050464.1	3.455e-54	58.75	SMESG000050464.1	[more]
SMESG000016243.1	1.173e-40	48.13	SMESG000016243.1	[more]
SMESG000016243.1	2.476e-40	48.13	SMESG000016243.1	[more]
SMESG000016191.1	7.628e-40	46.50	SMESG000016191.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30033279
GenBank	AKN21669.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30033279 ID=SMED30033279|Name=slc39a-4|organism=Schmidtea mediterranea sexual|type=transcript|length=2680bp
AATACATAGGTTGATGATTTTTAAATGAAGCTCATATTTTTAATTTTAAA
ATTATCAAAAGATTCAATGATTTCAAATATTATAGTCAAATCTTTTACTT
TTTTATTCATATTCCAACTTGGTGACTTTTCAAATCAAACAAATTCAAAT
TCAACAATATTGCCAACAATTCAAACCTTTCCACAAAACAGATCATCTGC
CAAATTAAAATCAAAACAAGAAATAATTTTCAAAACATCTATAGCAGATG
TTTATTTGAATTCTTTGAAAAATTCGTCAGACAATATGAGTGCATTCCTT
AGCTCCGAAGGTTTTTCGTCATTGATCCTAAAACTGGGATTGAGGAAACG
AAATAATATCTCAAAGACCTTTAACAATGTTTCTATAAAATGCCATTCTC
CTATTCAAATGCTGAGTTGGTTCAATAAAACAAAATCAGGACTTTCCAAA
GAAGATTTTATTACCCTTTGCCCATCGCTGCTTGTTCAAATGGTTTCAAG
AGTATGTCGACCAAATGTAACTCAGCCAATGAAACCAATGAAACCAATGA
ATAATACGAGCTCACCGGTTATAAATAATAATCTAGCAATTTGGCTATGC
AGTTTTGGAGCAGTTATTGTCATCAGTTTAGTGGGATTATTAGTAGTATG
GTTGATTCCAATAATGCCCAAGTCATATTACAATAGTATTTCTCAATTGT
TGATTGCTCTCGCCGTTGGATCCTTGGCAGGAGATGCTCTTCTGCATTTA
ATACCGCACGCATTAATGGATGACGGAGAAAAGGGCCATAGTCATAATGG
ACATAATAAGATGGTTTGGAAATCTTTAGTGGCGTTAATTGGAATTCATC
TGTTTTTCCTCACTGAAAGAATAACAATTCTTTATCAAAATCTAAGATCC
AAAAGGAAGTCTAAAAAGCAACATTTTTTGAAACTTTTAACCAAAAAGCT
ATCTTTGGAAAACTTTTATTCCGAAGCATCAGCCGGTGACAAATTTGAAG
ATTCAGAAAAAGCACCAGTGAAAAGTTCTGAAAATAAAGCTTTATCTACT
GGTAAATTACATTGGGCGTCAAAATCACGAAAATATAGTGGTAGTTCCAA
GGAACTAGTTCATGCTAGCAGTCATATCGGAATAGATGGCGAGGTAAATA
TTGGTGCTCATTTATGTAATCGTCCGAAAAGCAAGCCTCATGTCAACAGC
GATTGTCCAGACTCCATGAACTATGAGTTGTGTAACACAATAAATCCTTA
TTCAATGAATCCTGAGTCGAATGGATGTAATCCAAATAATTCGGAAGCAC
GATTACAAACTAACGGAGAAATCAAAACCGTGCAGCCGATTGAAGAAAGC
AAACCGAATTATTTATTAACTGATCGACAGTTGACAAATATTTCATCCGC
ACAAAATGAAACTAGCAATTGGTCGAATAAGGAAGACCACAAACTGCTTT
CTCCACAAATTCCTCCGGAAAATAATCCTAATAATGTCGAGATAAAAACT
GTTGGCACAAAACATTCTGACCATACAGAAAGATTGGAAATTGGAGCCGG
TGGTGCGACAGTAAAATCGAGTTTAGCGCATCCTTTTAAAAACAAACCTC
ACGGTCATCATCATGGACATAGCCATGACTTGAGTAGTGTTAAAGCGATT
GCATATACAGTCATTGCCGGAGATGGTCTTCATAATTTCTGTGATGGGAT
AGCGATTGGGGCAGCATTTGCTAATGACATTGGTGGAGGTTTATCGACCG
CTATAGCGGTTCTCTGTCATGAATTGCCCCACGAGCTTGGAGATTTCGTG
GTGTTACTTCATGCTGGAATGTCACTTAGAACTGCAATTTTCTATAATTT
AATGTCGAGTGTATTTTGTGCAATAGGTATGGTAATCGGTGTTCAGCTAG
GTAAATTGCCCTCAATTTCTAGTTGGATATTTATGCTCACTGCTGGGATG
TTTCTCTACATTGCTTTAGTTGATATGATGCCTGAACTCAGCACTCGGAG
GTTAAAAGGAAACAAAATATTTCATCGGCCCAGCATATTATTCCTGTGGC
AAAATATCGGTTTCGTAATTGGATCCGCCATAATGCTAGTTATAGCTTTA
TATGAAGAACATATGTTTTAGATGTTTACCACCTCTTTTTTGATGTCATC
TTCGCCTTTTCATTCTGTTTTCATCGTGTCAACTGGTGATTTTTCCGCTT
AAACTCAATATAATATATAAATATATATGTATACAATCATTTATAGATTT
GTAATTGTAATAATATTTTTGTATTTTCAATTTTTGTTATCTTATTATCC
ATCTTGACTTTTTTAATATCAAATATGCATTCACAATCGTTTTTTGTTTT
CATTTTTCGCCCTTCTATCTAAAATTCAGTTCAGATTTTTGTTTGCTTAC
TTCCGAGCGGCTGAGATGTTGCGTTAGATGAGAATTGTTAATATTTTTTT
AATTAATCCAATCTATATATCAATCGTTATATTTTATTGATTATTATTAT
TATATAAATTTGAAACTAATTTATTATTATTAATATTAATGTTATTTGGA
ATGTGAACATATTTTTTTCTCTGGTTTTGGTGGTTTTCAAAAAATATAGT
CGTTTATTTATTATATGTGATTGTTTCTGAATTTTTGTCAATGATATTTG
ATACGATTTTGTTTTTATCGTATATATATA

protein sequence of SMED30033279-orf-1

>SMED30033279-orf-1 ID=SMED30033279-orf-1|Name=SMED30033279-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=699bp
MKLIFLILKLSKDSMISNIIVKSFTFLFIFQLGDFSNQTNSNSTILPTIQ
TFPQNRSSAKLKSKQEIIFKTSIADVYLNSLKNSSDNMSAFLSSEGFSSL
ILKLGLRKRNNISKTFNNVSIKCHSPIQMLSWFNKTKSGLSKEDFITLCP
SLLVQMVSRVCRPNVTQPMKPMKPMNNTSSPVINNNLAIWLCSFGAVIVI
SLVGLLVVWLIPIMPKSYYNSISQLLIALAVGSLAGDALLHLIPHALMDD
GEKGHSHNGHNKMVWKSLVALIGIHLFFLTERITILYQNLRSKRKSKKQH
FLKLLTKKLSLENFYSEASAGDKFEDSEKAPVKSSENKALSTGKLHWASK
SRKYSGSSKELVHASSHIGIDGEVNIGAHLCNRPKSKPHVNSDCPDSMNY
ELCNTINPYSMNPESNGCNPNNSEARLQTNGEIKTVQPIEESKPNYLLTD
RQLTNISSAQNETSNWSNKEDHKLLSPQIPPENNPNNVEIKTVGTKHSDH
TERLEIGAGGATVKSSLAHPFKNKPHGHHHGHSHDLSSVKAIAYTVIAGD
GLHNFCDGIAIGAAFANDIGGGLSTAIAVLCHELPHELGDFVVLLHAGMS
LRTAIFYNLMSSVFCAIGMVIGVQLGKLPSISSWIFMLTAGMFLYIALVD
MMPELSTRRLKGNKIFHRPSILFLWQNIGFVIGSAIMLVIALYEEHMF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR003689	ZIP

Vocabulary: **molecular function**
Term	Definition
GO:0046873	metal ion transmembrane transporter activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0030001	metal ion transport
GO:0055085	transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003689	Zinc/iron permease	PFAM	PF02535	Zip	coord: 188..329 e-value: 3.8E-22 score: 79.0 coord: 448..691 e-value: 7.8E-49 score: 166.7
None	No IPR available	PANTHER	PTHR12191	SOLUTE CARRIER FAMILY 39	coord: 82..696
None	No IPR available	TMHMM	TMhelix		coord: 264..286
None	No IPR available	TMHMM	TMhelix		coord: 604..626
None	No IPR available	TMHMM	TMhelix		coord: 222..244
None	No IPR available	TMHMM	TMhelix		coord: 630..649
None	No IPR available	TMHMM	TMhelix		coord: 187..209
None	No IPR available	TMHMM	TMhelix		coord: 670..692