Rho GTPase-activating protein 7

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + + +    S  P   R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  513 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQN----SMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1008          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1082          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   15 EAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMK 76          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  577 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1072          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:    3 EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMK 66          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  577 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1072          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:    3 EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMK 66          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  621 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1116          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   47 EIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMK 110          

Query: 1851 WSHTSYSKDKSIPQYHHLLEL--SVTKFNL-----LKKFSILSCTSMLEKYCPQKNV-------------FNWRIPRLLP-------QKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEK---------DENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL-RMKKSNG----PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMI-FSESMSDEIFLTSNDNFGSVSNYSDVLIGH----IYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            W  ++   D+  P +  ++EL  S+   NL     L+K + L  +S+LE+    K V               W + RL+        QK++  ++    +FGV L VI NR G   P  IL +  +LR   P T GIFRK G+K RI EL+  +E           ENL   D   V+D+AD+LK +FRDLP+ L+T K+S     I + VP   +   L++A+  LPDENR AL+ L+ FL  +S+ S    M A+NLS+CF PSL  FQ   S  + ++P  R  K+ G    P+ K + E  A  LC+  +I    ++F +              G  ++ D  D N     +     + ++ ++++ L  D +     WT         + G+   IE  S R        +D   L+T++V +++   P  +   +  +R+ WD  +     +    EY+         PD        N   GH        H+  F  S   EI         SV    D L+G     I+   FLIE VS   +RV +I+RVDL G    WY+  +G  M R    LR
Sbjct:  780 WGSSTKLLDEQQPFFTDMVELARSIDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENL--LDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSL--FQLGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPD------------GLDDSMDAEDDNPNLTELGLKGPRSFLVDRVIDLIRDHSDQWKNWT---------IEGSFRGIEISSKRP-------SDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHL----EYVSA-------PDTDIHQYVVNETIGHP---TKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVSATIFDQRFLIEPVSGGQSRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1319          

Query: 1851 WSHTSYSKDKSIPQYHHLLEL--SVTKFNL-----LKKFSILSCTSMLEKYCPQKNV-------------FNWRIPRLLP-------QKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEK---------DENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL-RMKKSNG----PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMI-FSESMSDEIFLTSNDNFGSVSNYSDVLIGH----IYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            W  ++   D+  P +  ++EL  S+   NL     L+K + L  +S+LE+    K V               W + RL+        QK++  ++    +FGV L VI NR G   P  IL +  +LR   P T GIFRK G+K RI EL+  +E           ENL   D   V+D+AD+LK +FRDLP+ L+T K+S     I + VP   +   L++A+  LPDENR AL+ L+ FL  +S+ S    M A+NLS+CF PSL  FQ   S  + ++P  R  K+ G    P+ K + E  A  LC+  +I    ++F             +  G  ++ D  D N     +     + ++ ++++ L  D +     WT         + G+   IE  S R        +D   L+T++V +++   P  +   +  +R+ WD  +     +    EY+         PD        N   GH        H+  F  S   EI         SV    D L+G     I+   FLIE VS   +RV +I+RVDL G    WY+  +G  M R    LR
Sbjct:  956 WGSSTKLLDEQQPFFTDMVELARSIDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENL--LDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSL--FQLGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFM------------VPDGLDDSMDAEDDNPNLTELGLKGPRSFLVDRVIDLIRDHSDQWKNWT---------IEGSFRGIEISSKRP-------SDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHL----EYVSA-------PDTDIHQYVVNETIGHP---TKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVSATIFDQRFLIEPVSGGQSRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1495          

Query: 1851 WSHTSYSKDKSIPQYHHLLEL--SVTKFNL-----LKKFSILSCTSMLEKYCPQKNV-------------FNWRIPRLLP-------QKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEK---------DENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL-RMKKSNG----PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMI-FSESMSDEIFLTSNDNFGSVSNYSDVLIGH----IYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            W  ++   D+  P +  ++EL  S+   NL     L+K + L  +S+LE+    K V               W + RL+        QK++  ++    +FGV L VI NR G   P  IL +  +LR   P T GIFRK G+K RI EL+  +E           ENL   D   V+D+AD+LK +FRDLP+ L+T K+S     I + VP   +   L++A+  LPDENR AL+ L+ FL  +S+ S    M A+NLS+CF PSL  FQ   S  + ++P  R  K+ G    P+ K + E  A  LC+  +I    ++F             +  G  ++ D  D N     +     + ++ ++++ L  D +     WT         + G+   IE  S R        +D   L+T++V +++   P  +   +  +R+ WD  +     +    EY+         PD        N   GH        H+  F  S   EI         SV    D L+G     I+   FLIE VS   +RV +I+RVDL G    WY+  +G  M R    LR
Sbjct:  787 WGSSTKLLDEQQPFFTDMVELARSIDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENL--LDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSL--FQLGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFM------------VPDGLDDSMDAEDDNPNLTELGLKGPRSFLVDRVIDLIRDHSDQWKNWT---------IEGSFRGIEISSKRP-------SDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHL----EYVSA-------PDTDIHQYVVNETIGHP---TKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVSATIFDQRFLIEPVSGGQSRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1326          

Query: 1851 WSHTSYSKDKSIPQYHHLLEL--SVTKFNL-----LKKFSILSCTSMLEKYCPQKNV-------------FNWRIPRLLP-------QKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEK---------DENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL-RMKKSNG----PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMI-FSESMSDEIFLTSNDNFGSVSNYSDVLIGH----IYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            W  ++   D+  P +  ++EL  S+   NL     L+K + L  +S+LE+    K V               W + RL+        QK++  ++    +FGV L VI NR G   P  IL +  +LR   P T GIFRK G+K RI EL+  +E           ENL   D   V+D+AD+LK +FRDLP+ L+T K+S     I + VP   +   L++A+  LPDENR AL+ L+ FL  +S+ S    M A+NLS+CF PSL  FQ   S  + ++P  R  K+ G    P+ K + E  A  LC+  +I    ++F             +  G  ++ D  D N     +     + ++ ++++ L  D +     WT         + G+   IE  S R        +D   L+T++V +++   P  +   +  +R+ WD  +     +    EY+         PD        N   GH        H+  F  S   EI         SV    D L+G     I+   FLIE VS   +RV +I+RVDL G    WY+  +G  M R    LR
Sbjct:  787 WGSSTKLLDEQQPFFTDMVELARSIDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENL--LDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSL--FQLGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFM------------VPDGLDDSMDAEDDNPNLTELGLKGPRSFLVDRVIDLIRDHSDQWKNWT---------IEGSFRGIEISSKRP-------SDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHL----EYVSA-------PDTDIHQYVVNETIGHP---TKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVSATIFDQRFLIEPVSGGQSRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1326          

Query: 2070 FGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLN--NFDGYNVNDIAD------ILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSL 2543
            FGV L  I +  G   PP++  +  YL  H  T +G+FRK+     IK L+  + K E ++  N   Y  N+         +LKTFFR L + L T++L   L A+ + V K  +   +K  +  LP EN + L+ +I+FL+ +++ S    M A NLS+ F P+L
Sbjct:   48 FGVPLEFILSHCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAAL-SEVSKTEKSAAVKEFVKLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNL 212          

Query: 1911 LSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME----KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQ-NDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDT---NANKT-GWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGH 3440
            +S  +  +++K ++++ T  +E+YCP  ++ +NW +P+ + +K K+       +FGV L +I  R GQ  P  +   F +L+ +     GIFRK+G K RI +L++++E      E ++ FD     D+AD+LK +FR+LP+ LLT K+S T +AI+ ++P E + + ++ A+  LPDENR  L  L+EFL+ ++  S   +M + NL +C A S+F+   + GS++ + SP R  K +G P+ K LAE  A+H C+  MI +   ++           E L   +F+  ++S    +  +        W R  + +  + T      KT GW +IN          N     ++Y+K+G      DG  LR W+   +IEG P  +  ++  +R  WD ++ Q + +K++++  E  +   D      +   F VLR  Q  +   A +I   S+       +   FG+V        G +    +LIE   +  +RV  ++RVD+ G   +WY+ ++GH
Sbjct:  510 MSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIY-------TAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNW-RGYLYECTSATIKEGREKTRGWFSIN--------SLNDSSVDIAYKKVG------DGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDGQ----LTTDFCVLRSWQTDLPRGACVIVETSIDHA---KAKPLFGAVR-------GVVLASRYLIEPCGSGRSRVMHLARVDVKGKTPEWYNKNYGH 993          

Query:  393 ACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            AC WL+ AGFPQY QM+ D +FPI L  V +DH + +   L +L+RR+ +LN+ + ++
Sbjct:   50 ACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMR 107          

Query: 1911 LSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME----KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQ-NDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDT---NANKT-GWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGH 3440
            +S  +  +++K ++++ T  +E+YCP  ++ +NW +P+ + +K K+       +FGV L +I  R GQ  P  +   F +L+ +     GIFRK+G K RI +L++++E      E ++ FD     D+AD+LK +FR+LP+ LLT K+S T +AI+ ++P E + + ++ A+  LPDENR  L  L+EFL+ ++  S   +M + NL +C A S+F+   + GS++ + SP R  K +G P+ K LAE  A+H C+  MI +   ++           E L   +F+  ++S    +  +        W R  + +  + T      KT GW +IN          N     ++Y+K+G      DG  LR W+   +IEG P  +  ++  +R  WD ++ Q + +K++++  E  +   D      +   F VLR  Q  +   A +I   S+       +   FG+V        G +    +LIE   +  +RV  ++RVD+ G   +WY+ ++GH
Sbjct: 1844 MSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIY-------TAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNW-RGYLYECTSATIKEGREKTRGWFSIN--------SLNDSSVDIAYKKVG------DGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDGQ----LTTDFCVLRSWQTDLPRGACVIVETSID---HAKAKPLFGAVR-------GVVLASRYLIEPCGSGRSRVMHLARVDVKGKTPEWYNKNYGH 2327          

Query:  390 KACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIXXXXXXXXXXXXXXXXXXXXXXXXVLEQTALSSNWSYEPRTRRWSHI 788
            +AC WL+ AGFPQY QM+ D +FPI L  V +DH + +   L +L+RR+ +LN+ + ++               +    KP                          +E+  E  ALS +W+++P  RRWS I
Sbjct: 1383 EACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMR---------------LDQSHKP--------------------QTPQQKEESDDENFALSEHWTFQPHIRRWSRI 1480          

Query: 1911 LSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME----KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQ-NDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDT---NANKT-GWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGH 3440
            +S  +  +++K ++++ T  +E+YCP  ++ +NW +P+ + +K K+       +FGV L +I  R GQ  P  +   F +L+ +     GIFRK+G K RI +L++++E      E ++ FD     D+AD+LK +FR+LP+ LLT K+S T +AI+ ++P E + + ++ A+  LPDENR  L  L+EFL+ ++  S   +M + NL +C A S+F+   + GS++ + SP R  K +G P+ K LAE  A+H C+  MI +   ++           E L   +F+  ++S    +  +        W R  + +  + T      KT GW +IN          N     ++Y+K+G      DG  LR W+   +IEG P  +  ++  +R  WD ++ Q + +K++++  E  +   D      +   F VLR  Q  +   A +I   S+       +   FG+V        G +    +LIE   +  +RV  ++RVD+ G   +WY+ ++GH
Sbjct: 1844 MSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIY-------TAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNW-RGYLYECTSATIKEGREKTRGWFSIN--------SLNDSSVDIAYKKVG------DGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDGQ----LTTDFCVLRSWQTDLPRGACVIVETSID---HAKAKPLFGAVR-------GVVLASRYLIEPCGSGRSRVMHLARVDVKGKTPEWYNKNYGH 2327          

Query:  390 KACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIXXXXXXXXXXXXXXXXXXXXXXXXVLEQTALSSNWSYEPRTRRWSHI 788
            +AC WL+ AGFPQY QM+ D +FPI L  V +DH + +   L +L+RR+ +LN+ + ++               +    KP                          +E+  E  ALS +W+++P  RRWS I
Sbjct: 1383 EACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMR---------------LDQSHKP--------------------QTPQQKEESDDENFALSEHWTFQPHIRRWSRI 1480          

Query: 2031 QKQKLSLENTNFIFGVNLS--VIQNRFGQPFPPVILNIFSYLRKHGPT-TQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFS-LPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL 2591
            Q+ K++   T   FGV L   V+ +      PP++      L   G   T+GIFR++G    I  LK+ + + E+++     NV+ IA +LK+F RDL + LLT +L   +    ++ PKE +   +   +   LP+EN    +Y++EFL  +    D  KM + NL++ F P+    ++  +S   ++P+
Sbjct:  207 QQHKMA---TTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVD-LKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDW-PKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPI 392          

Query: 2031 QKQKLSLENTNFIFGVNLS--VIQNRFGQPFPPVILNIFSYLRKHGPT-TQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFS-LPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL 2591
            Q+ K++   T   FGV L   V+ +      PP++      L   G   T+GIFR++G    I  LK+ + + E+++     NV+ IA +LK+F RDL + LLT +L   +    ++ PKE +   +   +   LP+EN    +Y++EFL  +    D  KM + NL++ F P+    ++  +S   ++P+
Sbjct:  264 QQHKMA---TTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVD-LKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDW-PKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPI 449          

Query: 1779 QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKK---SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQ----EWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   RFGQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT KL  T L IY YVPKE + + ++ A+  + DENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N T   + M+K   +  P+ K L E  AA   +  MI   + LF++  + V  +  S       AP   +     H       +     ++  ++  L  D+     GW +            N    +LSY+K+G      DG  LR W+V +++E  P  +   +  +RH+WD D+   ++ + ++   E  + +  N       R F VLR  +  +      + S S+  E       +   V     +++      N+L+E   +  +R+T I RVDL G   +WY+  +GH     AA +RN
Sbjct:  565 ESTGMRERRDSGVGASLTRPKRLRWPSFQISNRLS----HSVASLQITSQSAAQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRFGQPLPLGMQQALRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESSPDDVNYEDQSAYDVADMVKQFFRDLPEPLLTSKLGETFLHIYQYVPKEQRLQAVQAAIMLMSDENREVLQTLLCFLSDVTSSVQENQMTPMNLAVCLAPSLFHLNILKKDNLTPRAMHMQKKYATGRPDQKDLNENLAATQGLAHMITECNRLFEIPHEMVTQSRNSYVEAELQAPTIEELCKRQHPEDDGEDEGSWPAFMEARLQGLLKDSREKAKGWVSCQST-------GNT---ELSYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHMWDVDLMNWKVSEVLDRQTEVFQYVL-NCMPPHPSRDFVVLRSWRTDLPRGTCSLVSVSIEHE-------DCPPVGGIRAIVME----SNYLLEPCGSGKSRLTHICRVDLKGRTPEWYNKAFGHLCAAEAARIRN 1109          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q+F DS+FPI +  V++DH   D   +  L RR+  LNK + +K
Sbjct:   55 EIEAKEACDWLRAAGFPQYAQLFEDSQFPIDISPVKKDHDFLDKDLVEPLCRRLNTLNKCASMK 118          

Query: 1779 QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKK---SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQ----EWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   RFGQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT KL  T L IY YVPKE + + ++ A+  + DENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N T   + M+K   +  P+ K L E  AA   +  MI   + LF++  + V  +  S       AP   +     H       +     ++  ++  L  D+     GW +            N    +LSY+K+G      DG  LR W+V +++E  P  +   +  +RH+WD D+   ++ + ++   E  + +  N       R F VLR  +  +      + S S+  E       +   V     +++      N+L+E   +  +R+T I RVDL G   +WY+  +GH     AA +RN
Sbjct:  929 ESTGMRERRDSGVGASLTRPKRLRWPSFQISNRLS----HSVASLQITSQSAAQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRFGQPLPLGMQQALRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESSPDDVNYEDQSAYDVADMVKQFFRDLPEPLLTSKLGETFLHIYQYVPKEQRLQAVQAAIMLMSDENREVLQTLLCFLSDVTSSVQENQMTPMNLAVCLAPSLFHLNILKKDNLTPRAMHMQKKYATGRPDQKDLNENLAATQGLAHMITECNRLFEIPHEMVTQSRNSYVEAELQAPTIEELCKRQHPEDDGEDEGSWPAFMEARLQGLLKDSREKAKGWVSCQST-------GNT---ELSYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHMWDVDLMNWKVSEVLDRQTEVFQYVL-NCMPPHPSRDFVVLRSWRTDLPRGTCSLVSVSIEHE-------DCPPVGGIRAIVME----SNYLLEPCGSGKSRLTHICRVDLKGRTPEWYNKAFGHLCAAEAARIRN 1473          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q+F DS+FPI +  V++DH   D   +  L RR+  LNK + +K
Sbjct:  419 EIEAKEACDWLRAAGFPQYAQLFEDSQFPIDISPVKKDHDFLDKDLVEPLCRRLNTLNKCASMK 482          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+KFS+L  T++LEK+    K+ +NW +P+ + ++ K+       +FGV   V   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD++K +FRDLP+ +LT KL+ T L +Y +VP E + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A +L++C APS+ +   + S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ+ P  +M+   +  + +   P       V  +      + ++ + +  L  + +    GW +         HG +    +L+Y+K+G      DG  +R W+V ++IE  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F  LR     +     ++ S S+        +DN    +    VL+         IE      +R+T   R DL G   DWY+  +GH      A +R+
Sbjct:  549 SAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILHL--NASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQI-PHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA--------HGPDNT--ELAYKKVG------DGHPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRNFITLRRWCSDLPKGVCVLVSSSV-------DHDNVQLEAGLRAVLL----TSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIRS 1038          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+KFS+L  T++LEK+    K+ +NW +P+ + ++ K+       +FGV   V   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD++K +FRDLP+ +LT KL+ T L +Y +VP E + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A +L++C APS+ +   + S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ+ P  +M+   +  + +   P       V  +      + ++ + +  L  + +    GW +         HG +    +L+Y+K+G      DG  +R W+V ++IE  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F  LR     +     ++ S S+        +DN    +    VL+         IE      +R+T   R DL G   DWY+  +GH      A +R+
Sbjct:  573 SAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILHL--NASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQI-PHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA--------HGPDNT--ELAYKKVG------DGHPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRNFITLRRWCSDLPKGVCVLVSSSV-------DHDNVQLEAGLRAVLL----TSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIRS 1062          

Query:  339 LISAKDTKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEI 563
            L+  K  + +  E + + AC WL+ AGFPQY Q++  S FPI +  V+ DH   D  SL AL RR+  LNK + +
Sbjct:   27 LLRRKAKQRQFAELEAKDACEWLRAAGFPQYAQLYEASLFPIEISAVRRDHEFLDQDSLKALCRRLTTLNKCAAM 101          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+KFS+L  T++LEK+    K+ +NW +P+ + ++ K+       +FGV   V   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD++K +FRDLP+ +LT KL+ T L +Y +VP E + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A +L++C APS+ +   + S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ+ P  +M+   +  + +   P       V  +      + ++ + +  L  + +    GW +         HG +    +L+Y+K+G      DG  +R W+V ++IE  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F  LR     +     ++ S S+        +DN    +    VL+         IE      +R+T   R DL G   DWY+  +GH      A +R+
Sbjct:  573 SAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILHL--NASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQI-PHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA--------HGPDNT--ELAYKKVG------DGHPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRNFITLRRWCSDLPKGVCVLVSSSV-------DHDNVQLEAGLRAVLL----TSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIRS 1062          

Query:  339 LISAKDTKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEI 563
            L+  K  + +  E + + AC WL+ AGFPQY Q++  S FPI +  V+ DH   D  SL AL RR+  LNK + +
Sbjct:   27 LLRRKAKQRQFAELEAKDACEWLRAAGFPQYAQLYEASLFPIEISAVRRDHEFLDQDSLKALCRRLTTLNKCAAM 101          

Query: 1740 DSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLEL---SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVM-------------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            D D+  +S +  +++ + +  +D  + + + R N  R+   S+            L++   SVT+ NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L++   R GQP P  I     YLR       G+FRK+G+K RI  L++  E + +   ++G +  D+AD+LK +FRDLP+ LLT KLS T L IY YVPKE + + +K A+  LPDENR  L+ L+ FLS ++   D+ +M   NL++C APSLF+       N++   +  K+S G P+ K L E  AA   +  MI     LF++ P+ +              +  E L  G  NA    D             Q +++  +  L  D      GW N           + +    LSY+K+       +G  LR WK  +DI   P  +   +  ++HLWD D+   ++I+ +++  +  + +  N       R F VLR  +  +   A ++   S+        +D    +    +VL+       +LIE  S+  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  510 DLDSTGNSFNDCEEATVIQARRDSGVGASLTRTNRHRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRN-VFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKI-PEEMSKCRNSYMEHDLRPVCLEELVNG--NAEGLCD------------YQSYLQENIDVLLKDAKDKFKGWVNC----------STSEQADLSYKKVC------EGPPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDIYQYVQ-NYMAPHPARDFVVLRTWRTNLAKGACVLSCTSVD-------HDRAPQLGVRVNVLMSR-----YLIEPGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIRD 1060          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+ AGFPQY Q++ D  FPI +  V++DH   D  ++ AL RR+  LNK + +K
Sbjct:   25 EAKEACDWLRAAGFPQYAQLYEDLLFPIDISSVKKDHDFLDRDAIEALCRRLNTLNKCAVMK 86          

Query: 1740 DSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLEL---SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVM-------------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            D D+  +S +  +++ + +  +D  + + + R N  R+   S+            L++   SVT+ NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L++   R GQP P  I     YLR       G+FRK+G+K RI  L++  E + +   ++G +  D+AD+LK +FRDLP+ LLT KLS T L IY YVPKE + + +K A+  LPDENR  L+ L+ FLS ++   D+ +M   NL++C APSLF+       N++   +  K+S G P+ K L E  AA   +  MI     LF++ P+ +              +  E L  G  NA    D             Q +++  +  L  D      GW N           + +    LSY+K+       +G  LR WK  +DI   P  +   +  ++HLWD D+   ++I+ +++  +  + +  N       R F VLR  +  +   A ++   S+        +D    +    +VL+       +LIE  S+  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  490 DLDSTGNSFNDCEEATVIQARRDSGVGASLTRTNRHRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRN-VFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKI-PEEMSKCRNSYMEHDLRPVCLEELVNG--NAEGLCD------------YQSYLQENIDVLLKDAKDKFKGWVNC----------STSEQADLSYKKVC------EGPPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDIYQYVQ-NYMAPHPARDFVVLRTWRTNLAKGACVLSCTSVD-------HDRAPQLGVRVNVLMSR-----YLIEPGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIRD 1040          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q++ D  FPI +  V++DH   D  ++ AL RR+  LNK + +K
Sbjct:    3 EIEAKEACDWLRAAGFPQYAQLYEDLLFPIDISSVKKDHDFLDRDAIEALCRRLNTLNKCAVMK 66          

Query: 1740 DSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLEL---SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVM-------------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            D D+  +S +  +++ + +  +D  + + + R N  R+   S+            L++   SVT+ NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L++   R GQP P  I     YLR       G+FRK+G+K RI  L++  E + +   ++G +  D+AD+LK +FRDLP+ LLT KLS T L IY YVPKE + + +K A+  LPDENR  L+ L+ FLS ++   D+ +M   NL++C APSLF+       N++   +  K+S G P+ K L E  AA   +  MI     LF++ P+ +              +  E L  G  NA    D             Q +++  +  L  D      GW N           + +    LSY+K+       +G  LR WK  +DI   P  +   +  ++HLWD D+   ++I+ +++  +  + +  N       R F VLR  +  +   A ++   S+        +D    +    +VL+       +LIE  S+  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  493 DLDSTGNSFNDCEEATVIQARRDSGVGASLTRTNRHRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRN-VFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKI-PEEMSKCRNSYMEHDLRPVCLEELVNG--NAEGLCD------------YQSYLQENIDVLLKDAKDKFKGWVNC----------STSEQADLSYKKVC------EGPPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDIYQYVQ-NYMAPHPARDFVVLRTWRTNLAKGACVLSCTSVD-------HDRAPQLGVRVNVLMSR-----YLIEPGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIRD 1043          

Query:  390 KACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            +AC WL+ AGFPQY Q++ D  FPI +  V++DH   D  ++ AL RR+  LNK + +K
Sbjct:    4 EACDWLRAAGFPQYAQLYEDLLFPIDISSVKKDHDFLDRDAIEALCRRLNTLNKCAVMK 62          

Query: 1740 DSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLEL---SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVM-------------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            D D+  +S +  +++ + +  +D  + + + R N  R+   S+            L++   SVT+ NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L++   R GQP P  I     YLR       G+FRK+G+K RI  L++  E + +   ++G +  D+AD+LK +FRDLP+ LLT KLS T L IY YVPKE + + +K A+  LPDENR  L+ L+ FLS ++   D+ +M   NL++C APSLF+       N++   +  K+S G P+ K L E  AA   +  MI     LF++ P+ +              +  E L  G  NA    D             Q +++  +  L  D      GW N           + +    LSY+K+       +G  LR WK  +DI   P  +   +  ++HLWD D+   ++I+ +++  +  + +  N       R F VLR  +  +   A ++   S+        +D    +    +VL+       +LIE  S+  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  555 DLDSTGNSFNDCEEATVIQARRDSGVGASLTRTNRHRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRN-VFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKI-PEEMSKCRNSYMEHDLRPVCLEELVNG--NAEGLCD------------YQSYLQENIDVLLKDAKDKFKGWVNC----------STSEQADLSYKKVC------EGPPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDIYQYVQ-NYMAPHPARDFVVLRTWRTNLAKGACVLSCTSVD-------HDRAPQLGVRVNVLMSR-----YLIEPGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIRD 1105          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q++ D  FPI +  V++DH   D  ++ AL RR+  LNK + +K
Sbjct:   39 EIEAKEACDWLRAAGFPQYAQLYEDLLFPIDISSVKKDHDFLDRDAIEALCRRLNTLNKCAVMK 102          

Query: 1740 DSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLEL---SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVM-------------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            D D+  +S +  +++ + +  +D  + + + R N  R+   S+            L++   SVT+ NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L++   R GQP P  I     YLR       G+FRK+G+K RI  L++  E + +   ++G +  D+AD+LK +FRDLP+ LLT KLS T L IY YVPKE + + +K A+  LPDENR  L+ L+ FLS ++   D+ +M   NL++C APSLF+       N++   +  K+S G P+ K L E  AA   +  MI     LF++ P+ +              +  E L  G  NA    D             Q +++  +  L  D      GW N           + +    LSY+K+       +G  LR WK  +DI   P  +   +  ++HLWD D+   ++I+ +++  +  + +  N       R F VLR  +  +   A ++   S+        +D    +    +VL+       +LIE  S+  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  521 DLDSTGNSFNDCEEATVIQARRDSGVGASLTRTNRHRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRN-VFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKI-PEEMSKCRNSYMEHDLRPVCLEELVNG--NAEGLCD------------YQSYLQENIDVLLKDAKDKFKGWVNC----------STSEQADLSYKKVC------EGPPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDIYQYVQ-NYMAPHPARDFVVLRTWRTNLAKGACVLSCTSVD-------HDRAPQLGVRVNVLMSR-----YLIEPGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIRD 1071          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+ AGFPQY Q++ D  FPI +  V++DH   D  ++ AL RR+  LNK + +K
Sbjct:    7 EAKEACDWLRAAGFPQYAQLYEDLLFPIDISSVKKDHDFLDRDAIEALCRRLNTLNKCAVMK 68          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLKMGSFNAPDKSDSN---DVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E  E+  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK  +  A    +S+   D  H +     Q+ +     ++K        GW +             +   +LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A           + LTS D+    +  + V + ++    +LIE   +  +++T++ R DL GH  +WYS  +GH        +R+ F+ +N
Sbjct:  588 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFL-----QDCVDGLFKEVKEKFK----GWVSY----------PTSEQAELSYKKV------SEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPRGACA---------LLLTSVDH--DRAPVAGVRV-NVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQN 1083          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   15 EAKEACDWLRVTGFPQYAQLYEDLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMK 76          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLKMGSFNAPDKSDSN---DVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E  E+  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK  +  A    +S+   D  H +     Q+ +     ++K        GW +             +   +LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A           + LTS D+    +  + V + ++    +LIE   +  +++T++ R DL GH  +WYS  +GH        +R+ F+ +N
Sbjct:  622 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFL-----QDCVDGLFKEVKEKFK----GWVSY----------PTSEQAELSYKKV------SEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYV-QNSMAPHPARDYVVLRTWRTNLPRGACA---------LLLTSVDH--DRAPVAGVRV-NVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQN 1117          

Query:  351 KDTKEEE-DEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            K+T+E    E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   38 KNTRERRLAEIEAKEACDWLRVTGFPQYAQLYEDLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMK 110          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK------MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E  E+  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK      +G  N+   +D             + ++++ +  L  +      GW +             +   +LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A           + LTS D+    +  + V + ++    +LIE   +  +++T++ R DL GH  +WYS  +GH        +R+ F+ +N
Sbjct: 1039 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPAD------------YRHFLQDCVDGLFKEVKEKFKGWVSY----------PTSEQAELSYKKV------SEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPRGACA---------LLLTSVDH--DRAPVAGVRV-NVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQN 1534          

Query:  360 KEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            ++E  E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:  459 EKEMAEIEAKEACDWLRVTGFPQYAQLYEDLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMK 527          

Query: 1374 KPNEFPR----ESY-PIGDSGWLNGRTGSF-ISRNNGQPDAEFKT------SKKNIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQR--LSDFESYTRYNNKDG----------STNFTENIDSDTRISSPSVI--DQSVLKEDE-------KDWELSSKINR-NNVTRWSHTSYS-KDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNI----NKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            KP  FP+    ES  P  +S  +N RTGS  + R  G    E +       + +  IYD  P   L  S  + L++ +  +  +          IL+H +  Q +  D  +  L + +S++      G          + +F  N  S+ R ++PS +  D++ L E E       +D  + + + R N   RWS    S + +  P   H+   +  + NLL++FS+L  T+++EKY    K+ + W +P+ + ++ K        +FGV L V   R GQP P  I     YLR +     G+FRK+G+K RI  L++  E   +  +++  +  D+AD++K FFRDLP+ L T+KLS T L IY YVPKE + + ++ A+  L DENR AL+ L+ FL  +    D+ +M   NL++C APSLF+  N     ++   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  + +S      + P   D        S      ++ + +  L+ +      GW       N D              L+++K+G      DG  L+ WK  +++E  P  +   +  +RHLWD D  Q ++++ +++  E  + + +    S VP   R F VLR  +  +      + S S+  E         G V          +    +LIE   +  +R+T I R+DL GH  +WYS  +GH        +RN
Sbjct:  284 KPGTFPKALSIESLSPTDNSNGVNWRTGSISLGRQQGPGMREPRLMSSCHRASRVSIYDNVPSSHLYASTGDLLDLEKDGLLPQ-------LDDILQHVNGIQEVVDDWSKNILPELQSHSTLAGDPGLSPFPSPNQVTLDFEGNSVSEGR-TTPSDVERDRTSLNESEATGVRERRDSGVGASLTRPNRRLRWSSFQLSHQPQPSPATPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTWSVPKFM-KRIKAPDYRDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPDNVSYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVCLAPSLFHL-NLLKKESSPKVIQKKYATGKPDQKDLNENLAAAQGLAHMITECNRLFEVPHEMVAQSRDSYLEAEIHVPSLEDLG-AQLAESGATFHTYLEHLVQGLQKEAKEKFKGWVTCSSPDNTD--------------LAFKKVG------DGHPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVERLDKQTEIYQYVLN----SMVPHPSRDFLVLRTWKTDLPKGMCTLVSLSVEYE----EAQLMGGVRAV-------VMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVTRIRN 981          

Query: 1374 KPNEFPR----ESY-PIGDSGWLNGRTGSF-ISRNNGQPDAEFKT------SKKNIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQR--LSDFESYTRYNNKDG----------STNFTENIDSDTRISSPSVI--DQSVLKEDE-------KDWELSSKINR-NNVTRWSHTSYS-KDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNI----NKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            KP  FP+    ES  P  +S  +N RTGS  + R  G    E +       + +  IYD  P   L  S  + L++ +  +  +          IL+H +  Q +  D  +  L + +S++      G          + +F  N  S+ R ++PS +  D++ L E E       +D  + + + R N   RWS    S + +  P   H+   +  + NLL++FS+L  T+++EKY    K+ + W +P+ + ++ K        +FGV L V   R GQP P  I     YLR +     G+FRK+G+K RI  L++  E   +  +++  +  D+AD++K FFRDLP+ L T+KLS T L IY YVPKE + + ++ A+  L DENR AL+ L+ FL  +    D+ +M   NL++C APSLF+  N     ++   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  + +S      + P   D        S      ++ + +  L+ +      GW       N D              L+++K+G      DG  L+ WK  +++E  P  +   +  +RHLWD D  Q ++++ +++  E  + + +    S VP   R F VLR  +  +      + S S+  E         G V          +    +LIE   +  +R+T I R+DL GH  +WYS  +GH        +RN
Sbjct:  402 KPGTFPKALSIESLSPTDNSNGVNWRTGSISLGRQQGPGMREPRLMSSCHRASRVSIYDNVPSSHLYASTGDLLDLEKDGLLPQ-------LDDILQHVNGIQEVVDDWSKNILPELQSHSTLAGDPGLSPFPSPNQVTLDFEGNSVSEGR-TTPSDVERDRTSLNESEATGVRERRDSGVGASLTRPNRRLRWSSFQLSHQPQPSPATPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTWSVPKFM-KRIKAPDYRDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPDNVSYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVCLAPSLFHL-NLLKKESSPKVIQKKYATGKPDQKDLNENLAAAQGLAHMITECNRLFEVPHEMVAQSRDSYLEAEIHVPSLEDLG-AQLAESGATFHTYLEHLVQGLQKEAKEKFKGWVTCSSPDNTD--------------LAFKKVG------DGHPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVERLDKQTEIYQYVLN----SMVPHPSRDFLVLRTWKTDLPKGMCTLVSLSVEYE----EAQLMGGVRAV-------VMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVTRIRN 1099          

Query:  369 EDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + E + ++AC WL+ AGFPQY Q++ DS+FPI++  V++DH   +   +  L RR+  LNK + ++
Sbjct:   55 QQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIAAVKKDHDFLERDLVEPLCRRLNTLNKCASMR 120          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLKMGSFNAPDK---SDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK  +  A  +    DS D  H +     Q+ + +   ++K        GW +           + +   +LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE   +  +++T++ R DL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  608 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRN-VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESTIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGRLCNDDSADYQHFL-----QDCVDSLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRATIEVPATPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLAR-----YLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRDSFSHQN 1103          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q++ D  FPI +  V+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   39 EIEAKEACDWLRAAGFPQYAQLYEDLLFPIDISSVKREHDFLDRDAIEALCRRLNTLNKCAVMK 102          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGV-NGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E  E+  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS+++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+ P+ +     S                +++    + R  ++++ +  L  +      GW +             +   +LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +  G+  ++F+           +D         +VL+       +LIE   +  +++T++ R DL GH  +WY+  +GH        +R+
Sbjct:  587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDYVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQV-PEEMSRCRNSYTEQELKPLTLEALGHLSNDQPADYRH-FLQDCVDGLFKEVKEKFKGWVSY----------PTSEQAELSYKKV------SEGPPLRLWRATIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYV-QNSMAPHPARDYVVLRTWRTNLPRGACALLFTS--------VDHDRAPVAGVRVNVLLS-----RYLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRD 1076          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   15 EAKEACDWLRVTGFPQYAQLYEDLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMK 76          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLK---MGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK   + +       DS D  H +     Q+ +     ++K        GW +           + +   +LSY+K+      ++G  LR W+ VI++   P  +   +  ++HLWD D+   ++I+ ++   E  + + +    S  P   R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE      +++T++ RVDL GH  +WY+  +GH        +R+ F+ +N
Sbjct: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFL-----QDCVDGLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQN----SMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1519          

Query:  357 TKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            +++E+ E + ++AC WL+  GFPQY Q++ D  FPI + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:  444 SEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMK 513          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLKMGSFNAPDKSDSN---DVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + ++ K+       +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E  E+  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY YVPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK  +  A    +S+   D  H +     Q+ +     ++K        GW +             +    LSY+K+      ++G  LR W+  I++  +P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A           + LTS D+    +  + V + ++    +LIE   +  +++T++ R DL GH  +WYS  +GH        +R+ F+ +N
Sbjct:  588 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFM-KRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFL-----QDCVDGLFKEVKEKFK----GWVSY----------PTSEQADLSYKKV------SEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQ-NSMAPHPARDYVVLRTWRTNLPRGACA---------LLLTSVDH--DRAPVAGVRV-NVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQN 1083          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+  GFPQY Q++ D  FP+ + LV+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   15 EAKEACDWLRVTGFPQYAQLYEDLLFPVDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMK 76          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI----THESLKMGSFNAPDK---SDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN-FAKEN 3488
            SV + NLL+K+S+L  T++LEKY P  K+ F+W +P+ + + +    ++ N +FGV L+V   R GQP P  I     YLR H     G+FRK+G+K RI+ L++  E   +  N++G +  D+AD+LK +FRDLP+ L+T+KLS T L IY  VPK+ + + +K A+  LPDENR  L+ L+ FLS ++    + +M   NL++C APSLF+       N++   ++ K+S G P+ K L E  AA   +  MI     LFQ+  +        T + LK  +  A  +    +S D  H +     Q+ + +   ++K        GW +           + +   +LSY+K+      ++G  LR W+  I++   P  +   +  ++HLWD D+   ++I+ ++   E  + +  N       R + VLR  +  +   A  +   S+        +D    V    +VL+       +LIE   +  +++T++ R DL GH  +WY+  +GH        +R+ F+ +N
Sbjct:  587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRN-VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQCVPKDQRLQAMKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGRLRNDESADYQHFL-----QDCVDSLFKEVKEKFK----GWVSY----------STSEQAELSYKKV------SEGPPLRLWRSTIEVPAMPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYV-QNSMAPHPARDYVVLRTWRTNLPKGACALLLTSV-------DHDRAPVVGVRVNVLLSR-----YLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQN 1082          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+  GFPQY Q++ D  FPI +  V+ +H   D  ++ AL RR+  LNK + +K
Sbjct:   15 EAKEACDWLRATGFPQYAQLYEDLLFPIDISSVKREHDFLDRDAIEALCRRLNTLNKCAVMK 76          

Query: 1359 LKLPD--KPNEFPR---ESYPIGDSG-WLNGRTGSFISRNNGQPDAEFKT--------------SKKNIIYD--------------LDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRI-SSPSVIDQSV----LKEDEKDWELSSKINRNNVTRWSHTSYSKDK--------SIPQYH---------HLLELSVTKFNLLKKFSILSCTSMLEKYCPQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMI--------THESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRNFAKEN 3488
             KLPD  KP  FP+     Y   + G  +N RTGSF   ++ + DA                  S +  +YD              LD ++S +  D+N   V+   I    +    P S  L   ST      D+  LSD ++ +     D S N  ++ D  +R  SSP   D  +    L  D+    +  +  R++    S T    D+        S  + H         H+  LSV +  +L+K S+   T ++EKY P ++ +NW +P  + ++ K    N   +FGV L V   R GQP P  +L+   YLRK      GIFRK+G++ RI++LK E+E +  L NF      D+AD+LK +FR+LP+ LLT+KLS   + I+ Y+P E + E L+ A+  LPDENR  L+ L+ FL  +S  +DD +M A NL++CFAPSLFN     S   + SP R +K+ G P+ + L EQ AAH C+ +++     LF + P T+M           + + +  FN     D     H       Q  ++    + K        GW +++         +      LSY+K+       DG  LR W+   +++G P      +KD+RH+WD D+ +   I++++   E  +        S  P   R F VLR  +  +      + S S+               +  +  + G +   ++LIE   +  +RVT ISR+D+ G   +WY   + +N + +   +R+  K++
Sbjct:  511 FKLPDDHKPGTFPKVLSTGYMEVEGGHGVNARTGSFSLGSDRKDDAAISAASVKRRGSAGPRLDSNRMSVYDNVEPEEDLESAQHELDMILSKVFEDIN---VLNKAIYGEDAEIVEPPSSSL--NSTVNKSDDDESHLSDLKNLSALETDD-SLNGNDDQDVTSRTNSSPDTSDHDITTGELSHDDSTENIEGRERRDSGVGSSLTRAPSDRRRQRIRWHSFQKSHRPSVSGRNTHISSLSVCQLMVLQKLSLCRLTGLIEKYSPNRSGWNWSMPGFM-KRHKTPNYNDRNVFGVPLLVTLQRTGQPLPQCMLSAMRYLRKTAKDAVGIFRKSGVRTRIQKLKNEVEANPELVNFQELQAYDVADLLKQYFRELPECLLTNKLSEVFINIFIYLPSEQRLEALQSAVVLLPDENREVLQSLLFFLYDISTQADDHQMTASNLAVCFAPSLFNMSGTKSVTQSPSPRRPRKNLGVPDARELQEQKAAHECLTTLVQECKKLFNI-PTTMMSKCRFSYIEQGDPVPLEEFNRRSSEDDQLAYHNFVDTAIQGLLKESRDKFK--------GWVSVS---------SVPTDVDLSYKKV------TDGHLLRLWRCSTEVDGPPFAALECVKDERHVWDEDLVKWRSIEKLDSQTEVFQYT----QSSMAPHPARDFCVLRSWRKDLPKGTCALVSTSIEH-----------PEAELNGAIQGVVLASHYLIEPCGSGKSRVTHISRIDMRGRTPEWYKKVYSYNCVNQMERIRDSLKQS 1242          

Query:  390 KACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIXXXXXXXXXXXXXXXXXXXXXXXXVLEQTALSSNWSYEPRTRRWSHIELSKP 803
            +AC WLKEAGFPQY QM++D +FPI +  V++DH   D  S+  L RR+  LNK + ++     + +  +  D                                       +Q ALS  W Y+   RRWS  +L  P
Sbjct:  155 EACRWLKEAGFPQYAQMYDDCQFPIDITSVEKDHDFLDRDSMQPLVRRLSTLNKCAVMRIGTPAKKLGDESDDE--------------------------------------DQCALSDKWKYQHNIRRWSRKDLGSP 254          

Query: 1827 INRNNVTRWSHTSYSKDKSIP-QYHHLLELSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKES-QCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQE-----WIRNKMLQLKNDTNANKTGWTNIN-----KDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHL-RNFA 3479
            I R    RWS  + S   SI  +   +  +S+ +  +LK  + L    +++++CP  K++ +W +P+ L + +     +   +FGV L+ +Q R GQP PP I+++   LR+ G +  GIFR+TG K R+  LK E++   ++ +F      D+AD++K + R+LP+ L+T KLS TL+ ++ +VP +  +   L+ A+  LPDENR  L+ L+ FL   ++ +D T+M+A NL++C APSLF F ++  + + +SP R +++ G P+ + L +  AA  CV  MI +   LF        ++ E  +  +F+A + ++   +  +   +  Q      ++ N    +  + +     WT  +     + F KKL                     +D   LR WK VI++E  P  +   I   +  WDPD+   EL++ I++  +  +    +P      R+  VLR  +      +H +++ S+       +                 I  +++LIEA     +RVT +SRVDL GH  +WY+  WGH++ R+  HL ++FA
Sbjct:  124 IRRGTKFRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLF-------TVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHCFAFVDNHAQMVGRECSEGAAKWTPFSSRCGVETFCKKL---------------------DDKCPLRLWKAVINVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPA-REQCVLRAWR-SAGSHSHCLYTASVRLPPTPLTLPT-------------LILNEDWLIEACGPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHLNKSFA 646          

Query: 2025 LPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNN---TMSPLRMKK-SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKT-GWTNINKDFIKKLH---GANAVIE--QLSYRKIGSN-HNDNDGIALRTWKVVIDI-EGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVK--LISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNY---SDVLIGHIYCDNFLIEAVST-KLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            +PQ     +  T  +FG +LS  Q R G P PP I+++  +L  +G T  G+FR+ G K RI  L++E+E+D N   F  +   DIAD+LK FFR+LP+ L T KL++ L+ +Y  VP   Q + L+W L SLPDENR+ L+ L+  L++LS++SD T+M A NL++CFAPSL+      S +    ++SP R+++ ++GP+ K LA+Q+AA L + +MI    +LFQ++    ++ H +L + S        + D+  ++      +WI+N +  L  + +++K+ GW  IN+D +K  +   GAN +++  ++ Y+KI ++  +     +LR W+  + I E +P  +     + R  WDP++ QM ++ +I++ ++  +  L S  P    +     +LRG Q  ++  +  + SES+ +  F ++N      +     S  ++GH+Y D+  I   +  +  RV  +SRVD+ G+  DWY N WGH + RR  +LR
Sbjct:   85 IPQLPIRCISYTGPVFGQSLSSWQRRLGYPLPPAIVHMMDHLELNGTTAHGLFRRPGGKSRILALREEIERDINWRKFSDWQPYDIADLLKQFFRELPECLFTSKLATVLVNVYICVPNSVQIDLLRWILISLPDENRLVLQKLLYLLNHLSRHSDVTEMSASNLAVCFAPSLYRLIKPSSLSTQGVSLSPRRLRRTTSGPDPKDLADQHAAQLSLSAMITLAPNLFQIS--CSLLDHSTL-LTSLTP----LAQDLESLIPNGDWPQWIQNSLTDLIRECSSSKSKGWNTINRDVMKHYNADSGANELLDNFEIHYKKIPTSIESKITSNSLRLWRCSLYIPETNPRVILNRFVETRSSWDPEVVQMTIVDQISDCVDLCELHLSSTYPQPKCL---LQLLRGIQYTLDDGSCAMLSESICNSAFSSTNTTHSLTTLSTSQSINVLGHVYEDHVYIRPDNNGRGCRVYLLSRVDVKGYGPDWYVNQWGHTLCRRLINLR 574          

Query: 1827 INRNNVTRWSHTSYSKDKSIP-QYHHLLELSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKES-QCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQE-----WIRNKMLQLKNDTNANKTGWTNIN-----KDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHL-RNFA 3479
            I R    RWS  + S   SI  +   +  +S+ +  +LK  + L    +++++CP  K++ +W +P+ L + +     +   +FGV L+ +Q R GQP PP I+++   LR+ G +  GIFR+TG K R+  LK E++   ++ +F      D+AD++K + R+LP+ L+T KLS TL+ ++ +VP +  +   L+ A+  LPDENR  L+ L+ FL   ++ +D T+M+A NL++C APSLF F ++  + + +SP R +++ G P+ + L +  AA  CV  MI +   LF        ++ E  +  +F+A + ++   +  +   +  Q      ++ N    +  + +     WT  +     + F KKL                     +D   LR WK V+++E  P  +   I   +  WDPD+   EL++ I++  +  +    +P      R+  VLR  +      +H +++ S+       +                 I  +++LIEA     +RVT +SRVDL GH  +WY+  WGH++ R+  HL ++FA
Sbjct:  124 IRRGTKFRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLF-------TVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHCFAFVDNHAQMVGRECSEGAAKWTPFSSRCGVETFCKKL---------------------DDKCPLRLWKAVMNVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPA-REQCVLRAWR-SAGSHSHCLYTASVRLPPTPLTLPT-------------LILNEDWLIEACGPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHLNKSFA 646          

Query: 1827 INRNNVTRWSHTSYSKDKSIP-QYHHLLELSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKES-QCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQE-----WIRNKMLQLKNDTNANKTGWTNIN-----KDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            I R    RWS  + S   SI  +   +  +S+ +  +LK  + L    +++++CP  K++ +W +P+ L + +     +   +FGV L+ +Q R GQP PP I+++   LR+ G +  GIFR+TG K R+  LK E++   ++ +F      D+AD++K + R+LP+ L+T KLS TL+ ++ +VP +  +   L+ A+  LPDENR  L+ L+ FL   ++ +D T+M+A NL++C APSLF F ++  + + +SP R +++ G P+ + L +  AA  CV  MI +   LF        ++ E  +  +F+A + ++   +  +   +  Q      ++ N    +  + +     WT  +     + F KKL                     +D   LR WK V+++E  P  +   I   +  WDPD+   EL++ I++  +  +    +P      R+  VLR  +      +H +++ S+       +                 I  +++LIEA     +RVT +SRVDL GH  +WY+  WGH++ R+  HL+
Sbjct:  124 IRRGTKFRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLF-------TVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHCFAFVDNHAQMVGRECSEGAAKWTPFSSRCGVETFCKKL---------------------DDKCPLRLWKAVMNVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPA-REQCVLRAWR-SAGSHSHCLYTASVRLPPTPLTLPT-------------LILNEDWLIEACGPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHLK 642          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNF---QNDGSSNNTMSPLRMKKSNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDV-THIMSTNLRQE------WIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+K+S+L  T++LEK+C   K+ ++W +P+ + + +    ++ + +FGV   +   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD+LK +FRDLP+ +LT KL+ T L IY +VP+  + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A+NL++C APS+ +    + DG+S   +S    K    P++K L+E  AA  C+  MI     LFQ       I HE + + S N+   +D+  +  H    N R E      ++++ +  L  +      GW ++N        G +    +LSY+K+G      DG  +R W++  ++E  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F VLR     +   A ++ S S+        +DN    +    VL+        LIE      +R+    R DL G   DWY+  +GH      A +R 
Sbjct:  541 SAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKH-VFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILHLNTSKRDGTSPRLIS---RKGGAKPDHKDLSENMAATQCLCHMITECKKLFQ-------IPHE-MMLQSRNSYVAADAQPLPLHGFGVNARGERVDYRAYLQDNVQCLLREAAEKSKGWHSVN--------GPDNT--ELSYKKVG------DGHPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRDFVVLRRWSSDLQRGACILVSSSV-------EHDNVQLEAGLRAVLL----TSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIRG 1030          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDV-THIMSTNLRQE------WIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+K+S+L  T++LEK+C   K+ ++W +P+ + + +    ++ + +FGV   +   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD+LK +FRDLP+ +LT KL+ T L IY +VP+  + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A+NL++C APS+ +     S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ       I HE + + S N+   +D+  +  H    N R E      ++++ +  L  +      GW ++N        G +    +LSY+K+G      DG  +R W++  ++E  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F VLR     +   A ++ S S+        +DN    +    VL+        LIE      +R+    R DL G   DWY+  +GH      A +R 
Sbjct:  565 SAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKH-VFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILHLNT--SKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQ-------IPHE-MMLQSRNSYVAADAQPLPLHGFGVNARGERVDYRAYLQDNVQCLLREAAEKSKGWHSVN--------GPDNT--ELSYKKVG------DGHPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRDFVVLRRWSSDLQRGACILVSSSV-------EHDNVQLEAGLRAVLL----TSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIRG 1054          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEI 563
            E + ++AC WL+ AGFPQYVQ++    FPI +  V+ DH   D  S+ AL RR+  LNK + +
Sbjct:   37 EVEAKEACDWLRAAGFPQYVQLYEAGLFPIEIASVRRDHEFLDHDSVRALCRRLTTLNKCAAM 99          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDV-THIMSTNLRQE------WIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+K+S+L  T++LEK+C   K+ ++W +P+ + + +    ++ + +FGV   +   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD+LK +FRDLP+ +LT KL+ T L IY +VP+  + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A+NL++C APS+ +     S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ       I HE + + S N+   +D+  +  H    N R E      ++++ +  L  +      GW ++N        G +    +LSY+K+G      DG  +R W++  ++E  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F VLR     +   A ++ S S+        +DN    +    VL+        LIE      +R+    R DL G   DWY+  +GH      A +R 
Sbjct:  562 SAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKH-VFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILHLNT--SKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQ-------IPHE-MMLQSRNSYVAADAQPLPLHGFGVNARGERVDYRAYLQDNVQCLLREAAEKSKGWHSVN--------GPDNT--ELSYKKVG------DGHPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRDFVVLRRWSSDLQRGACILVSSSV-------EHDNVQLEAGLRAVLL----TSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIRG 1051          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEI 563
            E + ++AC WL+ AGFPQYVQ++    FPI +  V+ DH   D  S+ AL RR+  LNK + +
Sbjct:   34 EVEAKEACDWLRAAGFPQYVQLYEAGLFPIEIASVRRDHEFLDHDSVRALCRRLTTLNKCAAM 96          

Query: 1914 SVTKFNLLKKFSILSCTSMLEKYCPQ-KNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG--PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDV-THIMSTNLRQE------WIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            S  + NLL+K+S+L  T++LEK+C   K+ ++W +P+ + + +    ++ + +FGV   +   R GQP P  I     YLR       GIFRK+G+K RI+ L++  E   +   + G +  D+AD+LK +FRDLP+ +LT KL+ T L IY +VP+  + + ++ A+  LPDENR  L+ L+ FLS ++  + + +M A+NL++C APS+ +     S  +  SP  + +  G  P++K L+E  AA  C+  MI     LFQ       I HE + + S N+   +D+  +  H    N R E      ++++ +  L  +      GW ++N        G +    +LSY+K+G      DG  +R W++  ++E  P  +   +  +RHLWD D+    +I+ +    E    I+D    S  P   R F VLR     +   A ++ S S+        +DN    +    VL+        LIE      +R+    R DL G   DWY+  +GH      A +R 
Sbjct:  555 SAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKH-VFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILHLNT--SKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQ-------IPHE-MMLQSRNSYVAADAQPLPLHGFGVNARGERVDYRAYLQDNVQCLLREAAEKSKGWHSVN--------GPDNT--ELSYKKVG------DGHPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITD----SMAPHPRRDFVVLRRWSSDLQRGACILVSSSV-------EHDNVQLEAGLRAVLL----TSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIRG 1044          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEI 563
            E + ++AC WL+ AGFPQYVQ++    FPI +  V+ DH   D  S+ AL RR+  LNK + +
Sbjct:   27 EVEAKEACDWLRAAGFPQYVQLYEAGLFPIEIASVRRDHEFLDHDSVRALCRRLTTLNKCAAM 89          

Query: 1941 KFSILSCTSMLEKY-CPQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKK---SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            KFS+L  T+++EKY    K+ + W +P+ + + +    ++ + +F V L +   R+GQP P  +     YLR       G+FRK+G+K RI  L++  +      +++     D+AD++K FFRDLP+ LLT KL  T L IY YVPKE + + ++ A+  + DENR  L+ L+ FLS ++   ++ +M   NL++C APSLF+   +   N+ +SP  ++K   +  P+ K L E  AA   +  MI   + LF++  + V  +  S         ++ +  +       +L Q  I+N +L+   D         NIN               +LS+RK+G      DG  LR W+V +++E  P  +   +  +RHLWD ++ Q ++++ +++  E V   + N       R F VLR  +  +   A ++ S S+  E  +      G V               +L+E   +  +R+T I RVDL G   +WY+  +GH      A +RN
Sbjct:  583 KFSLLRLTAIMEKYSISNKHGWTWSVPKFMKRMKGPEYKDKS-VFAVPLILHVQRYGQPLPLCLQLALRYLRSQCLDQVGLFRKSGVKSRILALRQMCDSSPESVDYEDQCAYDVADMVKQFFRDLPEPLLTSKLGETFLHIYQYVPKEQRLQAVQAAIMLMADENREVLQTLLCFLSDVTSSVEENQMTPMNLAVCLAPSLFHL--NIMKNDNLSPRAIQKKYATGRPDQKDLNENLAATHGLAHMITECNRLFEVPKEMVTQSRNSYMEAELLCEEEEEEVEEEGSYRCHL-QRQIQN-LLKEARDKTKCWVARPNINN-------------VELSFRKVG------DGSPLRRWRVSVEVEAPPCVVLNRVLRERHLWDSNLLQGKVLETLDKQTE-VYQYAINSMAPHPSRDFVVLRTWRTDMPKGACVLVSVSIDHEDSMPMAGVRGVVLE-----------SQYLLEQCGSGKSRLTHICRVDLKGKSLEWYNKAFGHLCAAEVASIRN 1061          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q++ DS+FPI +  V++DH   D   +  L RR+  LNK + +K
Sbjct:   44 EIEAKEACDWLRAAGFPQYAQLYEDSQFPIDISAVKKDHDFLDRDLVEPLCRRLNTLNKCAPMK 107          

Query: 2067 IFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKK--SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHES--------LKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +FGV L +   R GQP P  I     YLR       G+FRK+G+K RI+ L++  E      N++G +  D+AD+LK +FRDLP+ + T KL+ T L IY YVPKE Q + L+     LPDENR AL+ L+ FLS ++    + +M + NL++C APSLF+  N    +N+ S +R +K  +  P+ K L+E  AA   +  MI     LF++  + V     S        + +    AP  +        + + ++          L  +      GW   +      L  +  V    +Y+K+G      DG  LR WK  +++E  P  +   I+ +RHLWD D+ Q ++++ ++   E    +  N       R + VLR  +  +   + ++ + S+  E           V     V++   Y    LIE +    +R+T + R+D  G   +WY+  +GH    + A +R+
Sbjct:   25 VFGVPLLLNVQRTGQPLPQSIQQAMRYLRSQCLDQVGLFRKSGVKSRIQALREMNESGAESVNYEGQSAYDVADMLKQYFRDLPEPMFTSKLADTFLQIYQYVPKEQQLQALQAGTMLLPDENREALQTLLYFLSDVAAAVGENQMSSVNLAVCLAPSLFHL-NTVKRDNSTSRVRQRKYSTGKPDQKDLSENLAAIQGLAHMIAECKKLFKIPEEMVSQCQSSYMEHDTQPMSLAELGAPVTNGGGPPPAHLESCIQ---------GLLKEARDKFKGWVTCS-----SLESSTEV----AYKKVG------DGHLLRLWKTTVEVEAPPPRVLQRIRSERHLWDEDLLQWKVVETLDPNTEVFYYVL-NSMAPHPARDYLVLRSWRTDLPKGSCVLVATSVEHE-------EVPCVGEARAVVLASRY----LIEPLGANRSRLTHVCRIDTRGRSLEWYNKVFGHLCASKVAMIRD 466          

Query: 2070 FGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPL 2591
            FGV L  +    GQ  P V+ +  +YL++HG  T+GIFR++     ++E ++   + + ++     +V+  A ILKTF R+LP+ LLT  L   ++++   + K+++   +   +  LP+ENR  L +L++FL  +S +S   KM  +NL++ F P+L   +    +  TM+P+
Sbjct:  196 FGVGLKRLAENSGQLIPLVVRDTVAYLKEHGLQTEGIFRRSASTQALRETQERYNRGQPVDFQALGDVHLAAVILKTFLRELPEPLLTFSLFPYIVSVQG-LEKDARGAAVVEMVKKLPEENRAVLHHLLDFLKLVSPHSGVNKMSGENLAIVFGPNLVWERERSLNLATMAPV 368          

Query: 1992 KNVFNWRIPRLLPQK------QKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDEN--LNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLF 2546
            K  FN   P   P K       +   + T+ +F  NL       GQ  P V+ +   ++  +G   QGIFR +G +  + ++K   E+ E+  + + D +++N +A +LK +FR L + L   +    L+          +   ++  + +LP    V + YL+ FL++LS++SD+  MD  NL++CF P+L 
Sbjct:  310 KGDFNSFRPPFFPTKPPSAKRHRPRSQFTDKLFNGNLETFIQDTGQVIPLVVESCVRFINLYGLQHQGIFRVSGSQVEVNDIKNAFERGEDPLVEDEDSHDINSVAGVLKLYFRGLENSLFPKEKFHDLVMCVKMENLYERAAHIRKIILTLPRSTIVVMRYLLAFLNHLSQFSDENMMDPYNLAICFGPTLM 502          

Query: 2037 QKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLN-NFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLF--NFQN 2558
            +K  ++  +  FG+ L  +      P P  +     YL   G TT+G++R +G K     L+K+ E D +++      NVN +A  LK FF +LPD LL + +   L+   N   K  +   L+  L  LP  N    +Y+I  L  +S+YS +  M ++NLS+CF P+L   +FQ 
Sbjct: 1209 RKQEVKKESVYFGLPLVEVVQSPDNPIPLFVEKCVLYLESCGITTEGLYRVSGNKTEQDSLQKQFECDHSISYEAMDVNVNTVAGSLKIFFAELPDPLLPYDIHQDLMEAINIPDKTGRLLALRGKLKKLPHVNHEVFKYIITHLHKVSQYSSENYMTSENLSICFWPTLMRPDFQT 1385          

Query: 2067 IFGVNLSVIQNR-----FGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKD--ENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNGPNNKHLAEQNAAHLCVVSMI 2672
            +FGV LS +  +      G   P  +  + ++L + G  T+GIFR  G   RIK L++E+E    +    +D    +D A +LK F R+LP  LLT +  +   ++     ++ +   L   +  LP  NR  L+ ++E L  +S+ S  T+MD  N+SL  AP+LF      S +  + PL         N+  A   AA+  +V M+
Sbjct:  262 LFGVPLSTLLEQDQKISPGVKVPLFLQELLTHLEQTGLDTEGIFRIPGSSSRIKSLRQELEAGFYDGAVTWDDVRPHDAASLLKLFIRELPAPLLTAEYLTAFTSVEKIEIRKQRIRALNLLIILLPAANRDVLKAILELLLKVSEASTATRMDLWNVSLIMAPNLFM----SSGSALLQPL---------NRQFA---AAYAGLVRML 454          

Query: 2058 TNFIFGVNLSVIQNRFGQP-----------FPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKD-ENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFS-LPDENRVALEYLIEFLSYLSKYSD-----DTKMDAKNLSLCFAPSLFNFQNDGSSNN 2576
            T  +FG  L V+  ++G              P +I  + S LR+   + +GIFRK G   R++EL   ++ +     +F   N   ++ +LK F R+LP  +L+  L    +     +  E + + +   ++S LP  NR  LE L+ FL + S +S       +KMD  NLS    P++   ++   SN+
Sbjct:  724 TKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAK-IDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISND 913          

Query: 2067 IFGVNLS----------VIQ---NRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNN-FDG---YNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVP------------KESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQND 2561
            +FGV+L           +IQ   N  G   P VI     YL+++   T GIFR  G   R++EL+    K  +    F+G   +NV+DIA +LK +   L + L+        LA+Y+               KE   +  +     LP +NR  + YL   L+  ++      M A NL+    PSL +   D
Sbjct:   47 VFGVSLEESLKVAQEEVIIQKSTNEIGS-IPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVP-------LALYDIFRNPILENPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLLSHPKD 232          

Query: 2070 FGVNL-SVIQNRFGQPFPPVILNIFSY-LRKHGPTTQGIFRKTGMKCRIKELKKEMEKD-ENLNNF------DGYNVNDIADILKTFFRDLPDRLLTHKLSSTL---LAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSL 2543
            FGV L S+I+  F Q   P I+    Y + K G   +GI+RK+     + +LK+E++KD  N++           ++  +  +LKTFF  LPD +L   LSS +   L I +   +++   GL   +++LPD     L  L+  L  +  +    +M+ + L + + P++
Sbjct:  470 FGVPLESLIE--FEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGL---IYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTI 634          

Query: 2121 PVILNI---FSYLRKHGPTTQGIFRKTGMKCRIKELKKEM------EKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYN---------YVPKESQCEG------------LKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLF 2546
            P+IL++   F    +    ++GI+RK+G +  I+E++K+       +  E  N     ++N +  +LK + R LP+ + T ++   L+ +           +V  +   E             LK  L  LP E+   L  L E +  +++YS   +M   NL+L FAP L 
Sbjct:  805 PMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLI 976          

Query: 2067 IFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYN---YVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITH----ESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFN-VLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWY 3422
            +FGV +SV+  R GQP P  IL   +YL++    + GIFRK+G K RI  LK  ME +    +F+G +  D+AD+LK +FRDLPD +LT KL+ T + I+    Y+P E + E ++ A+  +PDENR AL+ L+ FL+ +++ S   +M+ KNL +CFAPSLF+    G+  +  +P R K++     +K L +  AAH C+  MI     LF +   T+M +     E  +  +     +S SN +    +      +I + +  +  +      GW N         H  +    ++SY+K+       DG  LR W+ VI+I+ SP  +   I D+RHLWD ++   +++++I+E ++    ++ +      P++ + VLR  +  +   A  +   S+S              +  +  +   +    +LIE +    +R+T I+R+D  G  S +Y
Sbjct:   17 VFGVPMSVVLQRSGQPLPRPILCAINYLQRTCVESVGIFRKSGGKQRINNLKDMMEDNPEHTDFEGMSPYDLADMLKQYFRDLPDPILTSKLAETFITIHTCKYYIPAELRVEAMQAAILLMPDENREALQTLLLFLNEVAENSAVNQMNEKNLGVCFAPSLFHLC--GTKEDPSAPKRQKRTPMIKASKELTDNLAAHECLTQMIAQVDKLFLVPEDTMMKSRFSYIEQSEPVTLEQLGRSKSNPLDDYRT------YIESCINGILKEAREKFKGWVN---------HSWHESSVEVSYKKV------RDGCPLRLWRGVIEIDASPEDVLKRIVDERHLWDEELEAWDVLEKIDEDMDVFYYVTRS--MILQPKRIHVVLRARRTNLAHGACALVCTSISH-----------PSAPMTPGVQATLLAQRYLIEPLEAGRSRLTHITRLDQKGRASVYY 441          

Query: 2118 PPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNF--DGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLR 2594
            P  +  +  +L  +  T +GI R  G   R+K L++E+E+  N   F  DG  V+D+A +LK F R+LP  LLT++   T  ++ N   +  Q + L   +  LP  +R  L  L+ FLS +  Y    KM+  N+S+  AP+LF+F    SS+  M  LR
Sbjct:   60 PLFLQEMIRFLDHNSLTEEGILRVGGATARMKALREEIEETFNEGAFSLDGRRVHDVAGLLKQFLRELPFPLLTYEYQPTFASVENIPDRRQQLQALNLLILLLPSIHRDCLRVLLTFLSRIISYEKQNKMNLNNVSMIMAPNLFHF----SSSKEMPSLR 216          

Query: 1989 QKNVFNWRIPRLLPQKQKLSLENT-NFIFGVNLS-VIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYN-YVPKESQC-EGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQN 2558
            +K + +  + R  PQ    S  NT N  FGV L  V ++R G P P V+  I  YL + G   +GIFR +G    ++ LK   ++D +  + +  +V  +A +LK F R+LP+  +   L++  + ++  Y      C + L+  L  LP  N   L++L  FL  +S   ++ KM    L++ F P+ F  ++
Sbjct:   75 RKKIQSPLVKRKGPQGSAGSQVNTGNKQFGVPLEEVTKSRDGSPIPWVLAKIVHYLSQCGLKHEGIFRVSGNHKVVESLKATFDRDGDA-DLEECDVMAVAGLLKLFLRELPEPPVPQALTTDFIKVHEVYGDDNPDCLDELRALLDKLPYLNYELLKFLCHFLVEVSMNEENNKMSTMALAIVFGPNFFRCKD 267          

Query: 2055 NTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDEN----LNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSN 2609
            N+  +FGV++  + +R     P +++     + K G    GI+R +G    +K LK+    DEN    L      +++ +A + K + RDLP+ L T +L    +  Y     E + E +     SLP  NR+   YL + L  +++ S+  KM   NLS  F P++        S  T SP+ + +  
Sbjct:  605 NSVGVFGVDIETVTSRESCDIPLIVIGCVREIEKRGLEEVGIYRLSGASSDVKRLKEGF--DENSQSALVLVSEADIHAVAGLFKMYLRDLPEPLFTDELYDKFVKAYAMADAEEKRETMLELFQSLPTPNRLTACYLFQHLRKVAEKSEVHKMGLNNLSTVFGPNVLR-----PSPKTSSPMDLAQGT 786          

Query: 2067 IFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFD-----GYNVNDIADILKTFFRDLPDRLLTHKLSSTLL-AIYNYVPK---ESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSL 2543
            +FG  L+V         P ++      + K G  + G++R +G   R KEL+     DEN    D       ++N I  ILK + R+LP+ L+T K++  L  A  N +     + Q + +   L  LPD NR  L +++  L ++ +  +  KMDA+NLS+C AP +
Sbjct:   25 VFGFRLNVTSELEQSSVPLLVRKCVLEIEKRGLESVGLYRISGNARRKKELRGFF--DENSEAVDISEENCPDINVITGILKDYLRELPEPLITEKMTEGLRKAAKNEIQDKKVDEQKQVMSELLSGLPDPNRHTLVFILNHLRHVMEKKEFNKMDARNLSVCLAPVM 190          

Query: 1647 ILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVID---------QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIE--------QLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDN--PDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +L+ D +R    E+  R +    + +F  N  ++++ ++PS +D         +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   R GQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT+KL  T L IY YVPK+ + + ++ A+  + DENR  L+ L+ FLS +S   ++ +M   N+++C APSLF+       N +   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  +  S      +AP                    I+    QL++D    +T      ++ +K+    +            +L Y+K+G      DG  LR W+V +++E  P  +   +  +RHLWD D+ Q ++ + +++  E  + + ++  P  S   R+F VLR  +  +   A  + S S+        +D   ++     +++      N+L+E   +  +R+T + R+DL G   DWY+  +GH     AA +RN
Sbjct:  501 LLQVDSER---EEAVGRQSASQITLDFEGNSVAESQ-TTPSDVDRDKVSLVEAESATLRERRDSGVGASLTRPKRLRWPSFQISNRIS----HSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHLNLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPT-------------------IQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSSSDNTELLYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPS---REFVVLRSWRTDLPKGACSLVSVSI-------EHDECPTIGGVRAIVLE----SNYLLEPCGSGKSRLTHLCRIDLKGRTPDWYNKAFGHLCAAEAARIRN 1087          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q+F DS+FPI ++ V+ DH   D   +  L RR+  LNK + +K
Sbjct:   55 EIEAKEACDWLRAAGFPQYAQLFEDSQFPIDIRPVKRDHDFLDKDLVEPLCRRLNTLNKCASMK 118          

Query: 1647 ILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVID---------QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIE--------QLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDN--PDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +L+ D +R    E+  R +    + +F  N  ++++ ++PS +D         +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   R GQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT+KL  T L IY YVPK+ + + ++ A+  + DENR  L+ L+ FLS +S   ++ +M   N+++C APSLF+       N +   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  +  S      +AP                    I+    QL++D    +T      ++ +K+    +            +L Y+K+G      DG  LR W+V +++E  P  +   +  +RHLWD D+ Q ++ + +++  E  + + ++  P  S   R+F VLR  +  +   A  + S S+        +D   ++     +++      N+L+E   +  +R+T + R+DL G   DWY+  +GH     AA +RN
Sbjct:  458 LLQVDSER---EEAVGRQSASQITLDFEGNSVAESQ-TTPSDVDRDKVSLVEAESATLRERRDSGVGASLTRPKRLRWPSFQISNRIS----HSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHLNLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPT-------------------IQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSSSDNTELLYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPS---REFVVLRSWRTDLPKGACSLVSVSI-------EHDECPTIGGVRAIVLE----SNYLLEPCGSGKSRLTHLCRIDLKGRTPDWYNKAFGHLCAAEAARIRN 1044          

Query:  381 DIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            + ++AC WL+ AGFPQY Q+F DS+FPI ++ V+ DH   D   +  L RR+  LNK + +K
Sbjct:   14 EAKEACDWLRAAGFPQYAQLFEDSQFPIDIRPVKRDHDFLDKDLVEPLCRRLNTLNKCASMK 75          

Query: 1647 ILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVID---------QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIE--------QLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDN--PDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +L+ D +R    E+  R +    + +F  N  ++++ ++PS +D         +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   R GQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT+KL  T L IY YVPK+ + + ++ A+  + DENR  L+ L+ FLS +S   ++ +M   N+++C APSLF+       N +   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  +  S      +AP                    I+    QL++D    +T      ++ +K+    +            +L Y+K+G      DG  LR W+V +++E  P  +   +  +RHLWD D+ Q ++ + +++  E  + + ++  P  S   R+F VLR  +  +   A  + S S+        +D   ++     +++      N+L+E   +  +R+T + R+DL G   DWY+  +GH     AA +RN
Sbjct:  471 LLQVDSER---EEAVGRQSASQITLDFEGNSVAESQ-TTPSDVDRDKVSLVEAESATLRERRDSGVGASLTRPKRLRWPSFQISNRIS----HSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHLNLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPT-------------------IQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSSSDNTELLYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPS---REFVVLRSWRTDLPKGACSLVSVSI-------EHDECPTIGGVRAIVLE----SNYLLEPCGSGKSRLTHLCRIDLKGRTPDWYNKAFGHLCAAEAARIRN 1057          

Query:  366 EEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            +EDE + ++AC WL+ AGFPQY Q+F DS+FPI ++ V+ DH   D   +  L RR+  LNK + +K
Sbjct:   22 QEDEIEAKEACDWLRAAGFPQYAQLFEDSQFPIDIRPVKRDHDFLDKDLVEPLCRRLNTLNKCASMK 88          

Query: 1647 ILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVID---------QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNG-PNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIE--------QLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDN--PDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +L+ D +R    E+  R +    + +F  N  ++++ ++PS +D         +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   R GQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT+KL  T L IY YVPK+ + + ++ A+  + DENR  L+ L+ FLS +S   ++ +M   N+++C APSLF+       N +   ++ K + G P+ K L E  AA   +  MI   + LF++  + V  +  S      +AP                    I+    QL++D    +T      ++ +K+    +            +L Y+K+G      DG  LR W+V +++E  P  +   +  +RHLWD D+ Q ++ + +++  E  + + ++  P  S   R+F VLR  +  +   A  + S S+        +D   ++     +++      N+L+E   +  +R+T + R+DL G   DWY+  +GH     AA +RN
Sbjct:  488 LLQVDSER---EEAVGRQSASQITLDFEGNSVAESQ-TTPSDVDRDKVSLVEAESATLRERRDSGVGASLTRPKRLRWPSFQISNRIS----HSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHLNLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPT-------------------IQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSSSDNTELLYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPS---REFVVLRSWRTDLPKGACSLVSVSI-------EHDECPTIGGVRAIVLE----SNYLLEPCGSGKSRLTHLCRIDLKGRTPDWYNKAFGHLCAAEAARIRN 1074          

Query:  327 VWDLLISAKDTKEEE-DEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
             WDLL   K+ KE    E + ++AC WL+ AGFPQY Q+F DS+FPI ++ V+ DH   D   +  L RR+  LNK + +K
Sbjct:   27 AWDLLW--KNVKERRLAEIEAKEACDWLRAAGFPQYAQLFEDSQFPIDIRPVKRDHDFLDKDLVEPLCRRLNTLNKCASMK 105          

Query: 1779 QSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVT-----KFNLLKKFSILSCTSMLEKYC-PQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKK---SNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIE--------QLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVP---RQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRN 3473
            +S    + +D  + + + R    RW     S   S    H +  L +T     + +LL+KFS+L  T+++EKY    K+ + W +P+ + + +    ++ N +FGV L V   R GQP P  +     YLR       G+FRK+G+K RI+ L++  E   +  N++  +  D+AD++K FFRDLP+ LLT+KL  T L IY YVPK+ + + ++ A+  + DENR  L+ L+ FLS +S   ++ +M   N+++C APSLF+       N  +SP  M+K   +  P+ K L E  AA   +  MI   + LF++  + V  +  S      +AP                    I+    QL++D    +T      ++ +K+    +            +L Y+K+G      DG  LR W+V +++E  P  +   +  +RHLWD D+ Q ++ + +++  E  + + +    S  P   R+F VLR  +  +   A  + S S+        +D   ++     +++      N+L+E   +  +R+T + R+DL G   DWY+  +GH     AA +RN
Sbjct:  844 ESATLRERRDSGVGASLTRPKRLRWPSFQISNRIS----HSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKN-VFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHLNLLKKDN--LSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPT-------------------IQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSSSDNTELLYKKVG------DGNPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLN----SMPPHPSREFVVLRSWRTDLPKGACSLVSVSI-------EHDECPTIGGVRAIVLE----SNYLLEPCGSGKSRLTHLCRIDLKGRTPDWYNKAFGHLCAAEAARIRN 1381          

Query:  375 EQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIK 566
            E + ++AC WL+ AGFPQY Q+F DS+FPI ++ V+ DH   D   +  L RR+  LNK + +K
Sbjct:  349 EIEAKEACDWLRAAGFPQYAQLFEDSQFPIDIRPVKRDHDFLDKDLVEPLCRRLNTLNKCASMK 412          

Query:  321 MNVWDLLISAKDTKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIXXXXXXXXXXXXXXXXXXXXXXXXVLEQTALSSNWSYEPRTRRWSHIELSKPPIVIKQDQNIPKLENYLGVSYPRPFVSIPEDNSSDNYQKPYQFRRPNCFPDSHRSFEPIIESNPEXXXXXXXXXXXXXXXXMASLQLKNKSPISPISPNDNQNSTALQATSSDSNRDSLKVDKPNNHILRSASMRLMKAVSRINPNQLSLRHKKDHVLTSPKPTNDDDFSNIKVPTSNEEMDFAKLKLPDKPNEFPRESYPIGDSGWLNGRTGSFISRNNGQPDAEFKTSKKNIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYCPQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRNFAKENXXXXXXXXXXXXXXXXXALSPGKDHSSPSINPQIFESAPETVL 3617
            MNVWDLLISAKDTKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIEDSSENEAENENEESDDEDDDKENVLEQTALSSNWSYEPRTRRWSHIELSKPPIVIKQDQNIPKLENYLGVSYPRPFVSIPEDNSSDNYQKPYQFRRPNCFPDSHRSFEPIIESNPENNDSLLKDNNDSLDHLMASLQLKNKSPISPISPNDNQNSTALQATSSDSNRDSLKVDKPNNHILRSASMRLMKAVSRINPNQLSLRHKKDHVLTSPKPTNDDDFSNIKVPTSNEEMDFAKLKLPDKPNEFPRESYPIGDSGWLNGRTGSFISRNNGQPDAEFKTSKKNIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYCPQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNGPNNKHLAEQNAAHLCVVSMINNTSSLFQ       ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRNFAKENLSLRLSSESSINNFSDSALSPGKDHSSPSINPQIFESAPETVL
Sbjct:    1 MNVWDLLISAKDTKEEEDEQDIRKACIWLKEAGFPQYVQMFNDSEFPISLKLVQEDHMDFDGGSLMALFRRIEILNKASEIKSALLTEDISSKITDSIPSFQKPYYEIIEDSSENEAENENEESDDEDDDKENVLEQTALSSNWSYEPRTRRWSHIELSKPPIVIKQDQNIPKLENYLGVSYPRPFVSIPEDNSSDNYQKPYQFRRPNCFPDSHRSFEPIIESNPENNDSLLKDNNDSLDHLMASLQLKNKSPISPISPNDNQNSTALQATSSDSNRDSLKVDKPNNHILRSASMRLMKAVSRINPNQLSLRHKKDHVLTSPKPTNDDDFSNIKVPTSNEEMDFAKLKLPDKPNEFPRESYPIGDSGWLNGRTGSFISRNNGQPDAEFKTSKKNIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQRLSDFESYTRYNNKDGSTNFTENIDSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYSKDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYCPQKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKSNGPNNKHLAEQNAAHLCVVSMINNTSSLFQ-------ITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIKKLHGANAVIEQLSYRKIGSNHNDNDGIALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIECVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVSNYSDVLIGHIYCDNFLIEAVSTKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLRNFAKENLSLRLSSESSINNFSDSALSPGKDHSSPSINPQIFESAPETVL 1092          

Query: 1383 EFPRESYPIGDSGWLNGRTGSFISR-------NNGQ--PDAEFKTSKK------------------NIIYDLDPVISLLESDVNSLEVMRSRIKSRASPDSAPTSPILRHKSTKQILKKDQQRLSDF-----ESYTRYNNKDGSTNFTENIDSDTRISSPSVIDQSVLKEDEKDWELSSKINRNNVTRWSHTSYS-KDKSIPQYHHLLELSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKS-NGPNNKHLAEQNAAHLCVVSMINNTSSLFQLNPKTVMITHESLKMGSFNAPDK--SDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIK-------KLHGANAVIEQLSYRKIGSNHN-DNDGI-ALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIE-CVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVS-----NYSDVLIGHIYCDNFLIEAV-STKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 3470
            E   +S  +G++G +N RTGSF++R       +N Q  P +   +  +                  N+  +L+PV+  L SD++SL+  R+ + +R   ++          ++K   KK + R  DF       +   +N D +    E+I++  + +S +        +     + +S   RN+  RWS  + + +  +  +   L  LS+ +F +LKK ++L  TS+LE + P QK+ FNW+ P+LL QK K +  +T+ +FG +LS  Q R GQP PPVI +   Y+R  GP + GIFR+ G K RI ELK+ +EK +++ +F  +   D+AD++K++FR LP+ L+T+KLSSTL++I  Y+P+++  E ++W + +LPDENR+ L+ L+ FLS L+K+S  T+M + NL++C +PSLF+  +  +S +++SP+RM+KS +GP+ + L +Q A H C+  MI++  SLF+L+ +T+      ++     +  K   D ND            WIR+K+  L N+ N     WT+  KD +K        LHG      +L Y+K  +  +  ++GI ++ TW++  +I+     +   I++ R  WD ++  + + +EI++ ++ C   +  NP  +   RQ  ++RG Q  ++G+ +++ S+S+ D   +T        +     N  D  + ++  D+ +IE + +++ +R+ W+SRVDL G  S+WY   W H +IRR  HL+
Sbjct:  349 ELSNDSIDMGEAGRINFRTGSFMTRYRRNSKLSNSQSSPRSVLISPSQHCVNWAWCKDEYNQPIIDNVEDELNPVLDSLFSDMDSLDNFRNILHNRRISNN------FDEFNSKDTCKK-ELRPKDFIIRKPHLHNEKSNIDKNVQTFEDIENRQQTNSLTRQGSENKFKKSSLKKSASARKRNHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTS-VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKRAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINS-SSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDW---------YSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGF-----ELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQT--QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYLPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 1072          

Query: 2046 SLENTNFI--FGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME--KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYV-PKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQND 2561
            S+EN N I  FG  L        QP PP+I N  + +  +G   QGIFR +G +  I ELK+  +  +D  +NN    +VN  A +LK +FR+L + + +  L   ++  +     K+S     +  + S+P E  V L YL  FL Y+S+  +D  MD+ NL++CF P L    N+
Sbjct:  506 SVENENLIKIFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNE 682          

Query: 2046 SLENTNFI--FGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME--KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYV-PKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQND 2561
            S+EN N I  FG  L        QP PP+I N  + +  +G   QGIFR +G +  I ELK+  +  +D  +NN    +VN  A +LK +FR+L + + +  L   ++  +     K+S     +  + S+P E  V L YL  FL Y+S+  +D  MD+ NL++CF P L    N+
Sbjct:  506 SVENENLIKIFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNE 682          

Query: 2046 SLENTNFI--FGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEME--KDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYV-PKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQND 2561
            S+EN N I  FG  L        QP PP+I N  + +  +G   QGIFR +G +  I ELK+  +  +D  +NN    +VN  A +LK +FR+L + + +  L   ++  +     K+S     +  + S+P E  V L YL  FL Y+S+  +D  MD+ NL++CF P L    N+
Sbjct:  506 SVENENLIKIFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNE 682