GCR027
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033206 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of GCR027 vs. Ensembl Human
Match: DRD2 (dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023]) HSP 1 Score: 137.887 bits (346), Expect = 1.102e-34 Identity = 123/473 (26.00%), Postives = 207/473 (43.76%), Query Frame = 2
Query: 161 YNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQR-SFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L E C N F++ ++IV+F++P I+ + Y+ +L +RK S A F+ L + L P M + K+ S ++RR + V +E E +P + TR + + + L D L P++ ++ K + + E R S K ++ K + + +KA Q L I+ +F+IC+LPFF+ ++++ C++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 34 YNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPL-LFGLNNADQNE------CIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRA-----FRAHLRAPLKGNCTHPED--MKLCTVIMKSNGSFPVNRRRV-----VQEAARRAQELEMEMLSSTSP--PERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPK----------IAKIFEIQTMPNGKTRTSLKTMSRRKLSQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSAFT---WLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 445
BLAST of GCR027 vs. Ensembl Human
Match: HTR2A (5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293]) HSP 1 Score: 131.339 bits (329), Expect = 3.411e-32 Identity = 85/237 (35.86%), Postives = 137/237 (57.81%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKT--REHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
NW+ + ++ +L++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++ Y + + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ ++++ W I I+ P+ +F L+ D +E S C + F+LI + V+FFIPL IM +TY LT+K L + EA L V+ L + KL+S F+ P + + SEK
Sbjct: 75 NWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWP-LPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIH-HSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGS----CLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSL-----QKEATL---CVSDLGTRAKLAS----FSFLPQSSLSSEK 293 HSP 2 Score: 65.0846 bits (157), Expect = 1.896e-10 Identity = 35/122 (28.69%), Postives = 60/122 (49.18%), Query Frame = 2
Query: 1193 PLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
P + LS ++ F+ S + Y+ + ++ I+ +KA + LGI+F LFV+ + PFF+ ++ K +L W+GY S NP+VY FN +R + R ++CQ
Sbjct: 285 PQSSLSSEKLFQRSIHREPGSYTG--------RRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQ 398
BLAST of GCR027 vs. Ensembl Human
Match: HTR2A (5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293]) HSP 1 Score: 131.339 bits (329), Expect = 3.411e-32 Identity = 85/237 (35.86%), Postives = 137/237 (57.81%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKT--REHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
NW+ + ++ +L++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++ Y + + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ ++++ W I I+ P+ +F L+ D +E S C + F+LI + V+FFIPL IM +TY LT+K L + EA L V+ L + KL+S F+ P + + SEK
Sbjct: 75 NWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWP-LPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIH-HSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGS----CLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSL-----QKEATL---CVSDLGTRAKLAS----FSFLPQSSLSSEK 293 HSP 2 Score: 65.0846 bits (157), Expect = 1.896e-10 Identity = 35/122 (28.69%), Postives = 60/122 (49.18%), Query Frame = 2
Query: 1193 PLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
P + LS ++ F+ S + Y+ + ++ I+ +KA + LGI+F LFV+ + PFF+ ++ K +L W+GY S NP+VY FN +R + R ++CQ
Sbjct: 285 PQSSLSSEKLFQRSIHREPGSYTG--------RRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQ 398
BLAST of GCR027 vs. Ensembl Human
Match: ADRA2B (adrenoceptor alpha 2B [Source:HGNC Symbol;Acc:HGNC:282]) HSP 1 Score: 128.642 bits (322), Expect = 1.880e-31 Identity = 106/466 (22.75%), Postives = 192/466 (41.20%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCG-PQNAYFILIATIVTFFIPLIIMTVTYVLTVKIL-YVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENT------------SMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAY-LVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
+ +++GN+LV ++V LR N FLVSLA +D L A L++P S + Y+ WC ++ +LDV F S+I+HLC IS+DRY A+ L+ + ++ R + ++ W+I I+ P ++ + D+ + C Q A++IL ++I +FF P +IM + Y+ I R+ A S +P +LA V S +++NG ++++ +L + N + + + + E ++ + + P LQ+ Q + L + R Q +L + + Q + + T+ ++ L ++ +FV+C+ PFF +Y L K C V + F W+GY S NP++Y FN FR ++R++
Sbjct: 24 LFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWY--FRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIY--KGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVL----ATLRGQ--------------VLLGRGVGAIGGQWWRRRAQLTREKRFTF-----------------------VLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVP---HGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL 441
BLAST of GCR027 vs. Ensembl Human
Match: ADRA2A (adrenoceptor alpha 2A [Source:HGNC Symbol;Acc:HGNC:281]) HSP 1 Score: 123.635 bits (309), Expect = 1.450e-29 Identity = 109/463 (23.54%), Postives = 194/463 (41.90%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQ-----NAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETE-NHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
+L+++GN LV I+V+ L+ N FLVSLA +D L A LV+P S + Y+ WC I+ +LDV F S+I+HLC IS+DRY ++ ++ + ++ R + ++ W+I I+ P + ++K + P+ ++++ + I +FF P +IM + YV +I + + + +AVA + +E++ NG SA ++E T+ N E P + T +E +S SD+ + + ++ + + Q K + + T + P A +R K + NR ++ L ++ +FV+C+ PFF Y + CSV T + F W GY S NP++Y FN FR +++++ C+ R
Sbjct: 60 LLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWY--FGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPL---ISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA-------------------APPGGTERRPNGLGPERSAGP----------GGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSS----SDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEER----VGAAKASRWRGRQ-------------NREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVG--CSVPRT---LFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKIL-CRGDR 461
BLAST of GCR027 vs. Ensembl Celegans
Match: ser-1 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:O17470]) HSP 1 Score: 147.132 bits (370), Expect = 2.426e-37 Identity = 117/476 (24.58%), Postives = 216/476 (45.38%), Query Frame = 2
Query: 161 YNWAYVGLFIIPML---SMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRR---SISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLP-FFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCY 1564
Y++ V LF++P+L + GN LVC+++ + L NYFL SLA++D L +VMP+S + + + T + CL++ DVF +++I+H+ IS+DRY + PL+ + R ++L+ +++ W++ ++CP+ + A+ T C + Y+I+ + +TF IPL IM VTY T ++L N AS++ + + K NG + HR+ + + S VN + K H ++ +N + + G+ +PS+ + +KQ Q+ + + WKS T ++ N + + S + + + +E+ KA + L ++F F IC+ P FF+ +L+ F + + + + + W+GY S NPI+Y FN FR + R+++CQC+
Sbjct: 4 YHFNGVALFLLPVLCLIGLIGNFLVCVAIATDRRLHNVTNYFLFSLALADLLVCCIVMPLSIVVEV-RHGVWTWSVSMCLLYVYSDVFLCSASIVHMSVISLDRYLGISQPLRT--RNRSKTLIFIKIAIVWVVTLLVSCPIAVLAMH--DTANILRNNQCMIFSRYYIIYGSTMTFLIPLCIMGVTYAKTTQLL-------------NKQASILSQ------------------KAGDKFNGNGLRRTMPHRKLGYARTYSATVNGTIANGKAIGAHGR-------TMSSISNIANGETADRLGTS--RPSINTNGHKQL----------QKASTINKWKSRT-SNLVTNFANKVGRRSSLQTATQDLANEH---------------------KATRVLAVVFACFFICWTPFFFINFLIGFGGENVQI---PDWVASIFLWLGYVSSTINPIIYTVFNKRFRQAFVRILRCQCF 399
BLAST of GCR027 vs. Ensembl Celegans
Match: ser-1 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:O17470]) HSP 1 Score: 147.132 bits (370), Expect = 3.509e-37 Identity = 117/476 (24.58%), Postives = 216/476 (45.38%), Query Frame = 2
Query: 161 YNWAYVGLFIIPML---SMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRR---SISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLP-FFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCY 1564
Y++ V LF++P+L + GN LVC+++ + L NYFL SLA++D L +VMP+S + + + T + CL++ DVF +++I+H+ IS+DRY + PL+ + R ++L+ +++ W++ ++CP+ + A+ T C + Y+I+ + +TF IPL IM VTY T ++L N AS++ + + K NG + HR+ + + S VN + K H ++ +N + + G+ +PS+ + +KQ Q+ + + WKS T ++ N + + S + + + +E+ KA + L ++F F IC+ P FF+ +L+ F + + + + + W+GY S NPI+Y FN FR + R+++CQC+
Sbjct: 52 YHFNGVALFLLPVLCLIGLIGNFLVCVAIATDRRLHNVTNYFLFSLALADLLVCCIVMPLSIVVEV-RHGVWTWSVSMCLLYVYSDVFLCSASIVHMSVISLDRYLGISQPLRT--RNRSKTLIFIKIAIVWVVTLLVSCPIAVLAMH--DTANILRNNQCMIFSRYYIIYGSTMTFLIPLCIMGVTYAKTTQLL-------------NKQASILSQ------------------KAGDKFNGNGLRRTMPHRKLGYARTYSATVNGTIANGKAIGAHGR-------TMSSISNIANGETADRLGTS--RPSINTNGHKQL----------QKASTINKWKSRT-SNLVTNFANKVGRRSSLQTATQDLANEH---------------------KATRVLAVVFACFFICWTPFFFINFLIGFGGENVQI---PDWVASIFLWLGYVSSTINPIIYTVFNKRFRQAFVRILRCQCF 447
BLAST of GCR027 vs. Ensembl Celegans
Match: tyra-3 (TYRAmine receptor [Source:UniProtKB/TrEMBL;Acc:Q2L6V9]) HSP 1 Score: 140.584 bits (353), Expect = 2.341e-35 Identity = 129/496 (26.01%), Postives = 227/496 (45.77%), Query Frame = 2
Query: 173 YVGLFIIPM--LSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCA-WIIPFSIACPLF------LFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTR-------TPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVE-----NTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXIN-----RSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLT-FLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQC 1561
++ LF++ + L+++GN LV +SV V +R N L SLA +D L ++VMP+S ++ N H+W C +W + DV ++I++LC IS+DRY A+ +PLK + + R R + L+ A W I F + P + LF + T FK + + + + + +F++PL++M Y KI V E EA L +V + +L+ + K R P ++ + N N S R + + N +++ K + H F+ T + +E N SM+L N P+ + + K ++ + S + + + + NT V + L+ + Q + ++ + Y + R RKA++T+GI+ L F+IC++PFF+ YLV+ F S ++ + F W+GYS S+ NPI+Y +N FR ++ L+ C
Sbjct: 73 FIALFLVMLILLTIFGNILVVLSVVVYKRMRTFTNILLTSLATADLLVGLIVMPMSLLDLLHN-------HRWPLGRFLCRMWATSDVLLCTASILNLCVISLDRYFAITSPLK-YPRTRSRKMAAGLLTAVWAISFVVCSPPWVIPSWNLFIDNNNNTGSSEDFKCAYSPSVAYRIYSALGSFYLPLLVMLFVY---FKIFRVA-SEREA-LMRQSVGTCRLSNRLTKTQQKNQRNNLRTASAPHSRTRVQVNHNCGRVNYSV---RPVEYA---NRVENSLKPS--HERFDSTDCEDSPPNGDSLEAGTTCNISMSLV--TNSPPNGLQKEAKNSMERECHSLADIVNSADTPVRKNTEVGVAPS-LSKRARQCNARLQPNNLLQKAHEHYQINGPGKAVRGSKEKMVYMRERKALKTIGIVVLGFIICWMPFFIMYLVEVFISDPVAESPIYRITSEFFLWLGYSNSVLNPIIYTMYNGDFRRCFRDLLSFGC 544
BLAST of GCR027 vs. Ensembl Celegans
Match: tyra-3 (TYRAmine receptor [Source:UniProtKB/TrEMBL;Acc:Q2L6V9]) HSP 1 Score: 139.043 bits (349), Expect = 3.022e-35 Identity = 127/486 (26.13%), Postives = 221/486 (45.47%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCA-WIIPFSIACPLF------LFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTR-------TPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVE-----NTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXIN-----RSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLT-FLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQC 1561
+L+++GN LV +SV V +R N L SLA +D L ++VMP+S ++ N H+W C +W + DV ++I++LC IS+DRY A+ +PLK + + R R + L+ A W I F + P + LF + T FK + + + + + +F++PL++M Y KI V E EA L +V + +L+ + K R P ++ + N N S R + + N +++ K + H F+ T + +E N SM+L N P+ + + K ++ + S + + + + NT V + L+ + Q + ++ + Y + R RKA++T+GI+ L F+IC++PFF+ YLV+ F S ++ + F W+GYS S+ NPI+Y +N FR ++ L+ C
Sbjct: 4 LLTIFGNILVVLSVVVYKRMRTFTNILLTSLATADLLVGLIVMPMSLLDLLHN-------HRWPLGRFLCRMWATSDVLLCTASILNLCVISLDRYFAITSPLK-YPRTRSRKMAAGLLTAVWAISFVVCSPPWVIPSWNLFIDNNNNTGSSEDFKCAYSPSVAYRIYSALGSFYLPLLVMLFVY---FKIFRVA-SEREA-LMRQSVGTCRLSNRLTKTQQKNQRNNLRTASAPHSRTRVQVNHNCGRVNYSV---RPVEYA---NRVENSLKPS--HERFDSTDCEDSPPNGDSLEAGTTCNISMSLV--TNSPPNGLQKEAKNSMERECHSLADIVNSADTPVRKNTEVGVAPS-LSKRARQCNARLQPNNLLQKAHEHYQINGPGKAVRGSKEKMVYMRERKALKTIGIVVLGFIICWMPFFIMYLVEVFISDPVAESPIYRITSEFFLWLGYSNSVLNPIIYTMYNGDFRRCFRDLLSFGC 465
BLAST of GCR027 vs. Ensembl Celegans
Match: tyra-3 (TYRAmine receptor [Source:UniProtKB/TrEMBL;Acc:Q2L6V9]) HSP 1 Score: 140.198 bits (352), Expect = 3.982e-35 Identity = 129/496 (26.01%), Postives = 227/496 (45.77%), Query Frame = 2
Query: 173 YVGLFIIPM--LSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCA-WIIPFSIACPLF------LFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTR-------TPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVE-----NTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXIN-----RSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLT-FLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQC 1561
++ LF++ + L+++GN LV +SV V +R N L SLA +D L ++VMP+S ++ N H+W C +W + DV ++I++LC IS+DRY A+ +PLK + + R R + L+ A W I F + P + LF + T FK + + + + + +F++PL++M Y KI V E EA L +V + +L+ + K R P ++ + N N S R + + N +++ K + H F+ T + +E N SM+L N P+ + + K ++ + S + + + + NT V + L+ + Q + ++ + Y + R RKA++T+GI+ L F+IC++PFF+ YLV+ F S ++ + F W+GYS S+ NPI+Y +N FR ++ L+ C
Sbjct: 101 FIALFLVMLILLTIFGNILVVLSVVVYKRMRTFTNILLTSLATADLLVGLIVMPMSLLDLLHN-------HRWPLGRFLCRMWATSDVLLCTASILNLCVISLDRYFAITSPLK-YPRTRSRKMAAGLLTAVWAISFVVCSPPWVIPSWNLFIDNNNNTGSSEDFKCAYSPSVAYRIYSALGSFYLPLLVMLFVY---FKIFRVA-SEREA-LMRQSVGTCRLSNRLTKTQQKNQRNNLRTASAPHSRTRVQVNHNCGRVNYSV---RPVEYA---NRVENSLKPS--HERFDSTDCEDSPPNGDSLEAGTTCNISMSLV--TNSPPNGLQKEAKNSMERECHSLADIVNSADTPVRKNTEVGVAPS-LSKRARQCNARLQPNNLLQKAHEHYQINGPGKAVRGSKEKMVYMRERKALKTIGIVVLGFIICWMPFFIMYLVEVFISDPVAESPIYRITSEFFLWLGYSNSVLNPIIYTMYNGDFRRCFRDLLSFGC 572
BLAST of GCR027 vs. Ensembl Fly
Match: Dop2R (gene:FBgn0053517 transcript:FBtr0343171) HSP 1 Score: 145.591 bits (366), Expect = 2.853e-36 Identity = 133/477 (27.88%), Postives = 216/477 (45.28%), Query Frame = 2
Query: 167 WAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLS--SSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHN----HFEMTPLLAKTTRNNFVENTSMNLCGSDNLKP------SLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDF----FFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
WA + L + P+L+++GN LV +SV E L+ NYF+VSLA++D L A++VMP + + +++ + + C + ++DV + S+I +L ISIDRY A+ P+K K R + + ++ W I +I P+ L L RE C NA FIL +++ +F+IP IIM Y K L + ++ A KP LS + + T+ ++E L+ S+ H I + S E E+ N + ++ F+ T + G+ +KP +QE TL + + KT + K N+ + + + K S K K ++ SA + RKA +TL I+ +F+ C+LPFF ++D F K C TA M T W+GY S NP++Y FNP FR ++++M
Sbjct: 378 WALI-LILFPILTLFGNILVILSVCRERSLQTVTNYFIVSLAIADLLVAVVVMPFAVYFLVNGAW--ALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNSRRVCLTILLVWAISAAIGSPIVL-GLNNTPNREPDV---CAFYNADFILYSSLSSFYIPCIIMVFLYWNIFKALRSRARKQRA----------ARKPHLSELTGGSVIENIAQTRRLAETALD------SSRHASRILPDEAATNTASGSNEEEDENAISPDIDDCHVIVNDKSTEFMLATVVEETGNVAMKPLSFVRYGVQE---AMTLARNDSTLSTTSKTSSRKDKKNSQAS-------RFTIYKVHKASKK-KREKSSA---------------KKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDCRPGLTAYMMTT---WLGYINSFVNPVIYTIFNPEFRKAFKKIM 802
BLAST of GCR027 vs. Ensembl Fly
Match: 5-HT2B (gene:FBgn0261929 transcript:FBtr0303603) HSP 1 Score: 132.494 bits (332), Expect = 5.806e-32 Identity = 80/257 (31.13%), Postives = 134/257 (52.14%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSF---KGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENH 973
GN LVC+++ E L+ NYFL+SLA++D + A+LVMP+ ++ Y+ + + CL W LDV F ++I+HLCTIS+DRY +L+ P++ K R + +++V W++ +++ PL L ++ H+S C + + L+ +IV F+IPL +M +TY LTV++L QR+ + A L + A R +++ G SS +H S NS D++ +NH
Sbjct: 90 GNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYF--PLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMSLPLSLM-----YSKNHASVLVNGTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKP----GPGNASSVLHAHS------ANSTDTDLSTLDNH 329 HSP 2 Score: 62.003 bits (149), Expect = 1.322e-9 Identity = 29/84 (34.52%), Postives = 47/84 (55.95%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
I +KA + LG++F FVI + PFFV L+ C + + + W+GY+ SM NPI Y FN +FR +++++ C+
Sbjct: 811 IRLEQKATKVLGVVFFTFVILWSPFFVLNLLPTVCAECE-ERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVLLCR 893
BLAST of GCR027 vs. Ensembl Fly
Match: 5-HT2B (gene:FBgn0261929 transcript:FBtr0339322) HSP 1 Score: 132.494 bits (332), Expect = 5.806e-32 Identity = 80/257 (31.13%), Postives = 134/257 (52.14%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSF---KGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENH 973
GN LVC+++ E L+ NYFL+SLA++D + A+LVMP+ ++ Y+ + + CL W LDV F ++I+HLCTIS+DRY +L+ P++ K R + +++V W++ +++ PL L ++ H+S C + + L+ +IV F+IPL +M +TY LTV++L QR+ + A L + A R +++ G SS +H S NS D++ +NH
Sbjct: 90 GNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYF--PLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMSLPLSLM-----YSKNHASVLVNGTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKP----GPGNASSVLHAHS------ANSTDTDLSTLDNH 329 HSP 2 Score: 62.003 bits (149), Expect = 1.322e-9 Identity = 29/84 (34.52%), Postives = 47/84 (55.95%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
I +KA + LG++F FVI + PFFV L+ C + + + W+GY+ SM NPI Y FN +FR +++++ C+
Sbjct: 811 IRLEQKATKVLGVVFFTFVILWSPFFVLNLLPTVCAECE-ERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVLLCR 893
BLAST of GCR027 vs. Ensembl Fly
Match: 5-HT2B (gene:FBgn0261929 transcript:FBtr0330144) HSP 1 Score: 132.109 bits (331), Expect = 7.072e-32 Identity = 80/257 (31.13%), Postives = 134/257 (52.14%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSF---KGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENH 973
GN LVC+++ E L+ NYFL+SLA++D + A+LVMP+ ++ Y+ + + CL W LDV F ++I+HLCTIS+DRY +L+ P++ K R + +++V W++ +++ PL L ++ H+S C + + L+ +IV F+IPL +M +TY LTV++L QR+ + A L + A R +++ G SS +H S NS D++ +NH
Sbjct: 90 GNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYF--PLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMSLPLSLM-----YSKNHASVLVNGTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKP----GPGNASSVLHAHS------ANSTDTDLSTLDNH 329 HSP 2 Score: 62.003 bits (149), Expect = 1.332e-9 Identity = 29/84 (34.52%), Postives = 47/84 (55.95%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
I +KA + LG++F FVI + PFFV L+ C + + + W+GY+ SM NPI Y FN +FR +++++ C+
Sbjct: 811 IRLEQKATKVLGVVFFTFVILWSPFFVLNLLPTVCAECE-ERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVLLCR 893
BLAST of GCR027 vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0330055) HSP 1 Score: 110.538 bits (275), Expect = 2.874e-25 Identity = 118/492 (23.98%), Postives = 202/492 (41.06%), Query Frame = 2
Query: 176 VGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIA-CPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTY--VLTVKILYVQRKEAEA---NLYSNAVASLVFKPKLSSS--------LAKFTRTPSTKVMSEKKLN-----------GKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGS-DNLKPSLQEDQYKQTLPQRQVSFREQQ--------KTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
+GL I ++++ GN V ++ +E L+ NY + SLA++D A LVMP+ A I N ++ + + C IW S DV ++I+HL I+ DRY + N + + + R + + + C W ++ P F + + D + Q+ + + AT TF++PL+++ Y + + +QR+ ++ L S V + K S L RTP + +L G+N N++ ++R S + + +L + H H + L A T ++ +M G PS + T+ + KN V + NP L+ +R + + + KA QTL I+ FVIC+LPFFV L K C + + + FL W+GY S NP++Y FNP FR ++R++
Sbjct: 97 LGLMI--LVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWI--LGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWK-DPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFGRNTNTANVYRTSNANEII--TLSQQVAHATQH-HLIASHLNAITP---LAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRER-------------------------KAAQTLAIITGAFVICWLPFFVMALTMSLCKECEIHTAVASL--FL-WLGYFNSTLNPVIYTIFNPEFRRAFKRIL 548
BLAST of GCR027 vs. Ensembl Zebrafish
Match: drd2a (dopamine receptor D2a [Source:ZFIN;Acc:ZDB-GENE-021119-2]) HSP 1 Score: 153.295 bits (386), Expect = 2.873e-40 Identity = 137/512 (26.76%), Postives = 227/512 (44.34%), Query Frame = 2
Query: 56 FEIITKTNLRETKFLGAFKMDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRY---RSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTK---VMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
E+ T E+ F A + N T +YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + RY R + V + WI+ F+I+CPL LF L T + + C N F++ ++IV+F++P II + YV +L +RK V +SS++ K T K V+ + N N + + + + N D + E N N +R + + + S + +L+E P+ V E+ + K + +P Q S K NK K + + +KA Q L I+ +F+IC+LPFF+ ++V+ + ++ ++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 1 MEVFTAYAFNESFFENASRDFNAT----EQGGRHQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISVVWILSFAISCPL-LFGLNNTVTHDDAL---CVIANPAFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVNTKR-----TCPVTDMDMSSTIKKCTHPDDVKLCTVIVKSSGNCPVNNKNVIFIKEVVN----NGDDIQMDEITNRN----------PSRQRKQDQSGGSQQNSRLVNSNLRETDISPPSPEAGVK-PERNGNTSSITKGAKAFEIQVSPTG--KTQTSVKTLNKRKISQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHIVNTYCQV------PPELYTAFTWLGYVNSAVNPIIYTTFNIEFRKAFIKILHC 448
BLAST of GCR027 vs. Ensembl Zebrafish
Match: drd2a (dopamine receptor D2a [Source:ZFIN;Acc:ZDB-GENE-021119-2]) HSP 1 Score: 153.295 bits (386), Expect = 2.873e-40 Identity = 137/512 (26.76%), Postives = 227/512 (44.34%), Query Frame = 2
Query: 56 FEIITKTNLRETKFLGAFKMDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRY---RSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTK---VMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
E+ T E+ F A + N T +YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + RY R + V + WI+ F+I+CPL LF L T + + C N F++ ++IV+F++P II + YV +L +RK V +SS++ K T K V+ + N N + + + + N D + E N N +R + + + S + +L+E P+ V E+ + K + +P Q S K NK K + + +KA Q L I+ +F+IC+LPFF+ ++V+ + ++ ++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 1 MEVFTAYAFNESFFENASRDFNAT----EQGGRHQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISVVWILSFAISCPL-LFGLNNTVTHDDAL---CVIANPAFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVNTKR-----TCPVTDMDMSSTIKKCTHPDDVKLCTVIVKSSGNCPVNNKNVIFIKEVVN----NGDDIQMDEITNRN----------PSRQRKQDQSGGSQQNSRLVNSNLRETDISPPSPEAGVK-PERNGNTSSITKGAKAFEIQVSPTG--KTQTSVKTLNKRKISQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHIVNTYCQV------PPELYTAFTWLGYVNSAVNPIIYTTFNIEFRKAFIKILHC 448
BLAST of GCR027 vs. Ensembl Zebrafish
Match: drd3 (dopamine receptor D3 [Source:ZFIN;Acc:ZDB-GENE-021119-1]) HSP 1 Score: 137.502 bits (345), Expect = 1.218e-34 Identity = 121/477 (25.37%), Postives = 210/477 (44.03%), Query Frame = 2
Query: 173 YVGLFIIPMLSM-WGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPL---KIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQ----TLPQRQVSFR--EQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
Y L+ + +L++ +GN LVCI+V E L+ NY +VSLA++D L A LVMP W + YLE + W C ++ +LDV ++I++LC ISIDRY A+ P+ H ++ S+++ V W++ F+++CPL LF T + + C N F++ +++V+F++P + + YV L +RK+ S V P + L + +S ++N E+ + R + L N L + +T + + P++ ++N C + E + + QV+ R E +K N ++ + + S R M +K K KA Q L I+ +F+IC+LPFFV ++++ + C + T W+GY S NP++Y FN FR + +++ C
Sbjct: 38 YAMLYSLLILAIVFGNVLVCIAVLRERALQTTTNYLVVSLAVADLLVASLVMP---WAV----YLEVVGGAWLFSRLYCNVFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHSSRKRVSVMIATV--WVLAFAVSCPL-LFGF---NTTDDPAV--CSISNPDFVIYSSVVSFYLPFAVTLLVYVRIYIFLRRRRKKITFRQGSGKVQPASAPPSVEMCLQDDAHK-EKRDLSPIRINVITESKEQVIRPRL----LANCLRRKRPQTAPAENSLLPPVI------------TLNYCSISQASFARTEQDANREEEEGGDEEQVAVRSCEVKKLANGRTHTSLRPPRAAHAMVCPSQARCRSMHSKEK-------------------------KATQMLAIVLGVFLICWLPFFVTHILNTHCRACHIPPEVYSAFT---WLGYVNSALNPVIYTTFNIEFRRAFIKILSC 454
BLAST of GCR027 vs. Ensembl Zebrafish
Match: drd3 (dopamine receptor D3 [Source:ZFIN;Acc:ZDB-GENE-021119-1]) HSP 1 Score: 137.502 bits (345), Expect = 1.292e-34 Identity = 121/477 (25.37%), Postives = 210/477 (44.03%), Query Frame = 2
Query: 173 YVGLFIIPMLSM-WGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPL---KIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQ----TLPQRQVSFR--EQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
Y L+ + +L++ +GN LVCI+V E L+ NY +VSLA++D L A LVMP W + YLE + W C ++ +LDV ++I++LC ISIDRY A+ P+ H ++ S+++ V W++ F+++CPL LF T + + C N F++ +++V+F++P + + YV L +RK+ S V P + L + +S ++N E+ + R + L N L + +T + + P++ ++N C + E + + QV+ R E +K N ++ + + S R M +K K KA Q L I+ +F+IC+LPFFV ++++ + C + T W+GY S NP++Y FN FR + +++ C
Sbjct: 50 YAMLYSLLILAIVFGNVLVCIAVLRERALQTTTNYLVVSLAVADLLVASLVMP---WAV----YLEVVGGAWLFSRLYCNVFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHSSRKRVSVMIATV--WVLAFAVSCPL-LFGF---NTTDDPAV--CSISNPDFVIYSSVVSFYLPFAVTLLVYVRIYIFLRRRRKKITFRQGSGKVQPASAPPSVEMCLQDDAHK-EKRDLSPIRINVITESKEQVIRPRL----LANCLRRKRPQTAPAENSLLPPVI------------TLNYCSISQASFARTEQDANREEEEGGDEEQVAVRSCEVKKLANGRTHTSLRPPRAAHAMVCPSQARCRSMHSKEK-------------------------KATQMLAIVLGVFLICWLPFFVTHILNTHCRACHIPPEVYSAFT---WLGYVNSALNPVIYTTFNIEFRRAFIKILSC 466
BLAST of GCR027 vs. Ensembl Zebrafish
Match: drd3 (dopamine receptor D3 [Source:ZFIN;Acc:ZDB-GENE-021119-1]) HSP 1 Score: 137.502 bits (345), Expect = 1.420e-34 Identity = 121/477 (25.37%), Postives = 210/477 (44.03%), Query Frame = 2
Query: 173 YVGLFIIPMLSM-WGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPL---KIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQ----TLPQRQVSFR--EQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
Y L+ + +L++ +GN LVCI+V E L+ NY +VSLA++D L A LVMP W + YLE + W C ++ +LDV ++I++LC ISIDRY A+ P+ H ++ S+++ V W++ F+++CPL LF T + + C N F++ +++V+F++P + + YV L +RK+ S V P + L + +S ++N E+ + R + L N L + +T + + P++ ++N C + E + + QV+ R E +K N ++ + + S R M +K K KA Q L I+ +F+IC+LPFFV ++++ + C + T W+GY S NP++Y FN FR + +++ C
Sbjct: 56 YAMLYSLLILAIVFGNVLVCIAVLRERALQTTTNYLVVSLAVADLLVASLVMP---WAV----YLEVVGGAWLFSRLYCNVFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHSSRKRVSVMIATV--WVLAFAVSCPL-LFGFN---TTDDPAV--CSISNPDFVIYSSVVSFYLPFAVTLLVYVRIYIFLRRRRKKITFRQGSGKVQPASAPPSVEMCLQDDAHK-EKRDLSPIRINVITESKEQVIRPRL----LANCLRRKRPQTAPAENSLLPPVI------------TLNYCSISQASFARTEQDANREEEEGGDEEQVAVRSCEVKKLANGRTHTSLRPPRAAHAMVCPSQARCRSMHSKEK-------------------------KATQMLAIVLGVFLICWLPFFVTHILNTHCRACHIPPEVYSAFT---WLGYVNSALNPVIYTTFNIEFRRAFIKILSC 472
BLAST of GCR027 vs. Ensembl Xenopus
Match: DRD2 (dopamine receptor D2 [Source:NCBI gene;Acc:100493063]) HSP 1 Score: 147.902 bits (372), Expect = 3.399e-38 Identity = 126/478 (26.36%), Postives = 215/478 (44.98%), Query Frame = 2
Query: 158 RYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSS-----LAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ + L ++ + ++GN LVCI+V E L+ NY +VSLA++D L A LVMP W + Y+E + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L +++ K C N F++ ++IV+F++P I+ + YV +L +RK S+ V K K + A F ++ + +KK+ + N H + + S E H +P + + N C + NL PS + YK E+ K V + P + S K +K K ++ + +KA Q L I+ +F+IC+LPFF+ ++++ C++ + + + W+GY S NPI+Y FN FR + +++ C
Sbjct: 27 HYNYYAMLLTLLIFVIVFGNVLVCIAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YMEVVG-EWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISVVWVLSFAISCPL-LFGL------NNTASKVCIIDNPAFVIYSSIVSFYVPFIVTLLVYVQIYIVLRKRRKRVNTKRNSHGVEVNAHKDKCTHPEDVKLCAVFVKSNGSFPTDKKKVVSEAGN----HPEDMDVEMM-----SSTSPPEKTKHKSASP-----NHHQLAVPATSNQCNNANL-PSPVDSPYKA----------EKNGHPKDSTKPAKVFEIQTMPNG--KTRTSIKTMSKRKLSQH------------------KEKKATQMLAIVLGVFIICWLPFFIIHILNMHCN-CNI---PQALYSAFTWLGYVNSAVNPIIYTTFNVEFRKAFIKILHC 440
BLAST of GCR027 vs. Ensembl Xenopus
Match: slc25a29 (solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 [Source:Xenbase;Acc:XB-GENE-5763797]) HSP 1 Score: 136.732 bits (343), Expect = 3.724e-34 Identity = 83/240 (34.58%), Postives = 137/240 (57.08%), Query Frame = 2
Query: 149 FHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
F NW + + ++++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++++Y ++ + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ + +++ W I I+ P+ +F L+ D ++ + C + FI+I + V FFIPLIIM +TY LT+K L + EA L N + + S LA F+ P + + SEK
Sbjct: 54 FSLEKNWPALLTVTVILVTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLNILNDYEWP-LHRKLCPVWIYLDVLFSTASIMHLCAISLDRYIAIRNPIH-HSRFNSRTKALAKIIAVWTISVGISMPVPVFGLQ-DDSKVFDQ-ENCSLSDENFIIIGSFVAFFIPLIIMVITYFLTIKSL-----QKEATLCINNLGA-------KSKLALFSFLPQSSISSEK 277 HSP 2 Score: 64.6994 bits (156), Expect = 2.198e-10 Identity = 32/87 (36.78%), Postives = 49/87 (56.32%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
I+ +KA + LGI+F LFVI + PFF+ ++ F K ++L W+GY S NP+VY FN +R + R ++C+ YR
Sbjct: 298 ISNEQKASKVLGIVFFLFVIMWCPFFITNVMAVFCKESCNEHVIGELLKVFVWIGYLSSAVNPLVYTLFNQTYRSAFSRYIQCR-YR 383
BLAST of GCR027 vs. Ensembl Xenopus
Match: slc25a29 (solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 [Source:Xenbase;Acc:XB-GENE-5763797]) HSP 1 Score: 137.117 bits (344), Expect = 3.949e-34 Identity = 83/240 (34.58%), Postives = 137/240 (57.08%), Query Frame = 2
Query: 149 FHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
F NW + + ++++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++++Y ++ + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ + +++ W I I+ P+ +F L+ D ++ + C + FI+I + V FFIPLIIM +TY LT+K L + EA L N + + S LA F+ P + + SEK
Sbjct: 83 FSLEKNWPALLTVTVILVTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLNILNDYEWP-LHRKLCPVWIYLDVLFSTASIMHLCAISLDRYIAIRNPIH-HSRFNSRTKALAKIIAVWTISVGISMPVPVFGLQ-DDSKVFDQ-ENCSLSDENFIIIGSFVAFFIPLIIMVITYFLTIKSL-----QKEATLCINNLGA-------KSKLALFSFLPQSSISSEK 306 HSP 2 Score: 64.3142 bits (155), Expect = 2.599e-10 Identity = 32/87 (36.78%), Postives = 49/87 (56.32%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
I+ +KA + LGI+F LFVI + PFF+ ++ F K ++L W+GY S NP+VY FN +R + R ++C+ YR
Sbjct: 327 ISNEQKASKVLGIVFFLFVIMWCPFFITNVMAVFCKESCNEHVIGELLKVFVWIGYLSSAVNPLVYTLFNQTYRSAFSRYIQCR-YR 412
BLAST of GCR027 vs. Ensembl Xenopus
Match: slc25a29 (solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 [Source:Xenbase;Acc:XB-GENE-5763797]) HSP 1 Score: 136.732 bits (343), Expect = 4.044e-34 Identity = 83/240 (34.58%), Postives = 137/240 (57.08%), Query Frame = 2
Query: 149 FHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
F NW + + ++++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++++Y ++ + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ + +++ W I I+ P+ +F L+ D ++ + C + FI+I + V FFIPLIIM +TY LT+K L + EA L N + + S LA F+ P + + SEK
Sbjct: 61 FSLEKNWPALLTVTVILVTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLNILNDYEWP-LHRKLCPVWIYLDVLFSTASIMHLCAISLDRYIAIRNPIH-HSRFNSRTKALAKIIAVWTISVGISMPVPVFGLQ-DDSKVFDQ-ENCSLSDENFIIIGSFVAFFIPLIIMVITYFLTIKSL-----QKEATLCINNLGA-------KSKLALFSFLPQSSISSEK 284 HSP 2 Score: 64.6994 bits (156), Expect = 2.181e-10 Identity = 32/87 (36.78%), Postives = 49/87 (56.32%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
I+ +KA + LGI+F LFVI + PFF+ ++ F K ++L W+GY S NP+VY FN +R + R ++C+ YR
Sbjct: 305 ISNEQKASKVLGIVFFLFVIMWCPFFITNVMAVFCKESCNEHVIGELLKVFVWIGYLSSAVNPLVYTLFNQTYRSAFSRYIQCR-YR 390
BLAST of GCR027 vs. Ensembl Xenopus
Match: slc25a29 (solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 [Source:Xenbase;Acc:XB-GENE-5763797]) HSP 1 Score: 135.961 bits (341), Expect = 5.830e-34 Identity = 83/240 (34.58%), Postives = 137/240 (57.08%), Query Frame = 2
Query: 149 FHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK 865
F NW + + ++++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++++Y ++ + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ + +++ W I I+ P+ +F L+ D ++ + C + FI+I + V FFIPLIIM +TY LT+K L + EA L N + + S LA F+ P + + SEK
Sbjct: 63 FSLEKNWPALLTVTVILVTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLNILNDYEWP-LHRKLCPVWIYLDVLFSTASIMHLCAISLDRYIAIRNPIH-HSRFNSRTKALAKIIAVWTISVGISMPVPVFGLQ-DDSKVFDQ-ENCSLSDENFIIIGSFVAFFIPLIIMVITYFLTIKSL-----QKEATLCINNLGA-------KSKLALFSFLPQSSISSEK 286 HSP 2 Score: 64.6994 bits (156), Expect = 2.331e-10 Identity = 32/87 (36.78%), Postives = 49/87 (56.32%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
I+ +KA + LGI+F LFVI + PFF+ ++ F K ++L W+GY S NP+VY FN +R + R ++C+ YR
Sbjct: 307 ISNEQKASKVLGIVFFLFVIMWCPFFITNVMAVFCKESCNEHVIGELLKVFVWIGYLSSAVNPLVYTLFNQTYRSAFSRYIQCR-YR 392
BLAST of GCR027 vs. Ensembl Mouse
Match: Drd2 (dopamine receptor D2 [Source:MGI Symbol;Acc:MGI:94924]) HSP 1 Score: 137.887 bits (346), Expect = 7.233e-35 Identity = 120/473 (25.37%), Postives = 210/473 (44.40%), Query Frame = 2
Query: 161 YNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSE-FKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L E C N F++ ++IV+F++P I+ + Y+ +L +RK S A F+ L + L P M + K+ S ++RR + + L+ E T +P+ + + + L + + +++ + + + R F E Q N ++ S K ++ K + + +KA Q L I+ +F+IC+LPFF+ ++++ C++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 34 YNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPL-LFGLNNTDQNE------CIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRA-----FRANLKTPLKGNCTHPED--MKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRT------------------SLKTMSRRKLSQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSAFT---WLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 444
BLAST of GCR027 vs. Ensembl Mouse
Match: Htr2a (5-hydroxytryptamine (serotonin) receptor 2A [Source:MGI Symbol;Acc:MGI:109521]) HSP 1 Score: 131.339 bits (329), Expect = 2.409e-32 Identity = 90/258 (34.88%), Postives = 145/258 (56.20%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKT--REHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEK--KLNGKNENSSAMHRRSIST 922
NW+ + ++ +L++ GN LV ++V +E L+ NYFL+SLA++D L LVMP+S ++ Y + + C +W LDV F+ ++I+HLC IS+DRY A++NP+ H + R+ ++++ W I I+ P+ +F L+ D +E S C + F+LI + V FFIPL IM +TY LT+K L + EA L V+ L + KLSS F+ P + + SEK + + E S RR++ +
Sbjct: 75 NWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWP-LPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIH-HSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGS----CLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSL-----QKEATL---CVSDLSTRAKLSS----FSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQS 314 HSP 2 Score: 65.0846 bits (157), Expect = 1.193e-10 Identity = 35/122 (28.69%), Postives = 61/122 (50.00%), Query Frame = 2
Query: 1193 PLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
P + LS ++ F+ S + Y+ + ++ I+ +KA + LGI+F LFV+ + PFF+ ++ K + +L W+GY S NP+VY FN +R + R ++CQ
Sbjct: 285 PQSSLSSEKLFQRSIHREPGSYAG--------RRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQ 398
BLAST of GCR027 vs. Ensembl Mouse
Match: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C [Source:MGI Symbol;Acc:MGI:96281]) HSP 1 Score: 127.872 bits (320), Expect = 3.000e-31 Identity = 70/197 (35.53%), Postives = 121/197 (61.42%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKE 751
NW + + +I ++++ GN LV ++V +E L NYFL+SLA++D L +LVMP+S ++ +Y + + C +W SLDV F+ ++I+HLC IS+DRY A++NP++ H + R+ ++++ W I ++ P+ + L D+++ + C + F+LI + V FFIPL IM +TY LT+ YV R++
Sbjct: 55 NWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDY-VWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIE-HSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLR-DESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTI---YVLRRQ 245 HSP 2 Score: 65.855 bits (159), Expect = 7.325e-11 Identity = 29/84 (34.52%), Postives = 46/84 (54.76%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
IN +KA + LGI+F +F+I + PFF+ ++ EK+L W+GY S NP+VY FN I+R + + ++C
Sbjct: 304 INNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCD 387
BLAST of GCR027 vs. Ensembl Mouse
Match: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C [Source:MGI Symbol;Acc:MGI:96281]) HSP 1 Score: 127.872 bits (320), Expect = 3.000e-31 Identity = 70/197 (35.53%), Postives = 121/197 (61.42%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKE 751
NW + + +I ++++ GN LV ++V +E L NYFL+SLA++D L +LVMP+S ++ +Y + + C +W SLDV F+ ++I+HLC IS+DRY A++NP++ H + R+ ++++ W I ++ P+ + L D+++ + C + F+LI + V FFIPL IM +TY LT+ YV R++
Sbjct: 55 NWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDY-VWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIE-HSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLR-DESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTI---YVLRRQ 245 HSP 2 Score: 65.855 bits (159), Expect = 7.325e-11 Identity = 29/84 (34.52%), Postives = 46/84 (54.76%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
IN +KA + LGI+F +F+I + PFF+ ++ EK+L W+GY S NP+VY FN I+R + + ++C
Sbjct: 304 INNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCD 387
BLAST of GCR027 vs. Ensembl Mouse
Match: Adra2b (adrenergic receptor, alpha 2b [Source:MGI Symbol;Acc:MGI:87935]) HSP 1 Score: 125.176 bits (313), Expect = 2.065e-30 Identity = 109/466 (23.39%), Postives = 190/466 (40.77%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCG-PQNAYFILIATIVTFFIPLIIMTVTYVLTVKI--------LYVQRKEAEA-----NLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSV-SSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
+ +++GN+LV ++V LR N FLVSLA +D L A L++P S + Y+ WC ++ +LDV F S+I+HLC IS+DRY A+ L+ + ++ R + ++ W+I I+ P ++ + D+ E C Q A++IL ++I +FF P +IM + Y+ I L +R E + + V + P L S L+ +K G+ + S L S+ + K T + E ++ + P LQ+ Q + L + R Q +L + + S Q + + ++R ++ L ++ +FV+C+ PFF +Y + IC + F W+GY S NP++Y FN FR ++R++
Sbjct: 24 LFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWY--FWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIY--KGDQRPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGA--EEDEEEVEECEPQTLPASPASVFNPPLQQPQTSRVL----ATLRGQ--------------VLLSKNVGVASGQWWRRRTQ-----------------------LSREKRFTFVLAVVIGVFVVCWFPFFFSYSLG---AICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL 439
BLAST of GCR027 vs. UniProt/SwissProt
Match: sp|P24628|DRD2A_XENLA (D(2) dopamine receptor A OS=Xenopus laevis OX=8355 GN=drd2-a PE=2 SV=1) HSP 1 Score: 145.591 bits (366), Expect = 1.020e-36 Identity = 130/482 (26.97%), Postives = 215/482 (44.61%), Query Frame = 2
Query: 161 YNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSS-----LAKFTRTPSTKVMSEKKL-----NGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ + L ++ + ++GN LVCI+V E L+ NY +VSLA++D L A LVMP W + Y+E + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L ++ K C N F++ ++IV+F++P I+ + YV +L +RK S VA K K + + F ++ + +KK+ GK+ M S STS E H +P N + N C + +L S E YK E+ K V + P + S K +K K ++ + +KA Q L I+ +F+IC+LPFF+ ++++ C++ + + + W+GY S NPI+Y FN FR + +++ C
Sbjct: 28 YNYYAMLLTLLVFVIVFGNVLVCIAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WAV----YMEVVG-EWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISVVWVLSFAISCPL-LFGL------NNTGSKVCIIDNPAFVIYSSIVSFYVPFIVTLLVYVQIYIVLRKRRKRVNTKRNSRGVAVDAHKDKCTHPEDVKLCSVFVKSNGSFPADKKKVILVQEAGKHPEDMEMEMMS-STS-----------PPEKTKHKSASP-----DHNQLAVPATSNQCKNASLT-SPVESPYKA----------EKNGHPKDSTKPAKVFEIQSMPNG--KTRTSIKTMSKKKLSQH------------------KEKKATQMLAIVLGVFIICWLPFFIIHILNMHCN-CNI---PQALYSAFTWLGYVNSAVNPIIYTTFNVEFRKAFIKILHC 442
BLAST of GCR027 vs. UniProt/SwissProt
Match: sp|Q17232|OAR_BOMMO (Octopamine receptor OS=Bombyx mori OX=7091 PE=2 SV=1) HSP 1 Score: 139.043 bits (349), Expect = 4.212e-34 Identity = 122/472 (25.85%), Postives = 211/472 (44.70%), Query Frame = 2
Query: 182 LFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLF------ALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQC 1561
L +I + ++ GN LV +SV+ LR N+F+VSLA++D AILV+P++ +I QW C +W + D+ S+I++LC I++DRY A+ +P+ ++ ++ + WI+ I+ P L E D +S G F++ ++ +F+IPL+IMTV Y +I +K + +++ +SS K+ S + + N N R ++ + + H ++TP R ++ S N L + L R S E + H E+ + ++ K+ + K ++ +A Y + EKQ + R R+A +TLGI+ +FV+C+LPFFV YLV F C +S+ K + F+ W+GY S NP++Y FN FR +++L+ +C
Sbjct: 61 LTMIIISTVVGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNV--------AYSILGQWVFGIYVCKMWLTCDIMCCTSSILNLCAIALDRYWAITDPINYAQKRTLERVLFMIGIVWILSLVISSPPLLGWNDWPEVFEPDTPCRLTSQPG-------FVIFSSSGSFYIPLVIMTVVY---FEIYLATKKRLRDRAKATKIST------ISSGRNKYETKESDPNDQDSVSSDANPNEHQGGTRLVA------------ENEKKHRTRKLTPKKKPKRRYWSKDDKSHNKLIIPILSNENSVTDIGENLENRNTS-SESNSKETH-----------EDNMIEITEAAPVKIQKRPKQNQTNAVY--QFIEEKQRISLTRERRAARTLGIIMGVFVVCWLPFFVIYLVIPFCVSCCLSN---KFINFITWLGYVNSALNPLIYTIFNMDFRRAFKKLLFIKC 479
BLAST of GCR027 vs. UniProt/SwissProt
Match: sp|P61168|DRD2_MOUSE (D(2) dopamine receptor OS=Mus musculus OX=10090 GN=Drd2 PE=1 SV=2) HSP 1 Score: 137.887 bits (346), Expect = 5.059e-34 Identity = 120/473 (25.37%), Postives = 210/473 (44.40%), Query Frame = 2
Query: 161 YNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSE-FKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L E C N F++ ++IV+F++P I+ + Y+ +L +RK S A F+ L + L P M + K+ S ++RR + + L+ E T +P+ + + + L + + +++ + + + R F E Q N ++ S K ++ K + + +KA Q L I+ +F+IC+LPFF+ ++++ C++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 34 YNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPL-LFGLNNTDQNE------CIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRA-----FRANLKTPLKGNCTHPED--MKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRT------------------SLKTMSRRKLSQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSAFT---WLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 444
BLAST of GCR027 vs. UniProt/SwissProt
Match: sp|P61169|DRD2_RAT (D(2) dopamine receptor OS=Rattus norvegicus OX=10116 GN=Drd2 PE=1 SV=1) HSP 1 Score: 137.887 bits (346), Expect = 6.024e-34 Identity = 120/473 (25.37%), Postives = 210/473 (44.40%), Query Frame = 2
Query: 161 YNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSE-FKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L E C N F++ ++IV+F++P I+ + Y+ +L +RK S A F+ L + L P M + K+ S ++RR + + L+ E T +P+ + + + L + + +++ + + + R F E Q N ++ S K ++ K + + +KA Q L I+ +F+IC+LPFF+ ++++ C++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 34 YNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPL-LFGLNNTDQNE------CIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRA-----FRANLKTPLKGNCTHPED--MKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRT------------------SLKTMSRRKLSQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSAFT---WLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 444
BLAST of GCR027 vs. UniProt/SwissProt
Match: sp|Q25188|OAR_HELVI (Octopamine receptor OS=Heliothis virescens OX=7102 PE=2 SV=1) HSP 1 Score: 137.502 bits (345), Expect = 1.419e-33 Identity = 124/474 (26.16%), Postives = 211/474 (44.51%), Query Frame = 2
Query: 182 LFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLF------ALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLP-----QRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKT-KTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
L +I + ++ GN LV +SV+ LR N+F+VSLA++D AILV+P++ +I QW C +W + D+ S+I++LC I++DRY A+ +P+ ++ +++ + W++ I+ P L E D +S G F++ ++ +F+IPL+IMTV Y F+ L++ R +TK+ + K N H + DS E ++ H +T L++ + + + Q K +P E + +N +SN+ T E+ L ++ K +K K ++ SA Y + EKQ + R R+A +TLGI+ +FV+C+LPFFV YLV F C +S+ K + F+ W+GY S NP++Y FN FR +++L+
Sbjct: 59 LTLIIISTIVGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNV--------AYSILGQWVFGIYVCKMWLTCDIMCCTSSILNLCAIALDRYWAITDPINYAQKRTLERVLLMIGVVWVLSLIISSPPLLGWNDWPDVFEPDTPCRLTSQPG-------FVIFSSSGSFYIPLVIMTVVY---------------------------FEIYLATKKRLRDRAKATKISTISSGQNKYNNKDDHHDQ-----------DSVSSEANHNEHQGVTRLVSDNEKKKRTRKLTPKKKPKRKYWSKDDKSQNKLIIPILSNENSVTDMGENLENRNTSSESNSKET-HEDDLIEVNETVPVKTHHKKPKPNQQSAVY--QFIEEKQRISLTRERRAARTLGIIMGVFVVCWLPFFVIYLVIPFCASCCLSN---KFINFITWLGYCNSALNPLIYTIFNMDFRRAFKKLL 473
BLAST of GCR027 vs. TrEMBL
Match: A0A193KU74 (GCR027 OS=Schmidtea mediterranea OX=79327 GN=gcr027 PE=2 SV=1) HSP 1 Score: 1002.28 bits (2590), Expect = 0.000e+0 Identity = 495/496 (99.80%), Postives = 495/496 (99.80%), Query Frame = 2
Query: 113 MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 1600
MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKP LQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR
Sbjct: 1 MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPPLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 496
BLAST of GCR027 vs. TrEMBL
Match: A0A193KUM1 (GCR037 OS=Schmidtea mediterranea OX=79327 GN=gcr037 PE=2 SV=1) HSP 1 Score: 334.724 bits (857), Expect = 3.824e-105 Identity = 199/475 (41.89%), Postives = 276/475 (58.11%), Query Frame = 2
Query: 167 WAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDK-TREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA-----NLYSNAVASLVFKPKL-SSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRV 1570
WA++ L +IP+++++GN LV +SV++E L+ RFNYFLVSLA+SDFLCAILVMP+S KM+ HQ CL WYSLDVFFTA+TIIHLCTISIDRY AL NPL+ H KR SL +++ +W+IPF IACPLFL +L+++ +E SSFKGCGP NA FI+ A IVTF +PL+IM ++Y+LTVK + Q K ++ + S S ++K + S+SL ++KV + + E S + SIST D + + N+F TP + EN + + + + ++P R+ + R + + + + VL N R S + T + S Y I +SRKAVQ LGI+F LFV CY+PFFV YL DFF C S M+++ EW+GYS SM NP+VYH FNP FR T+ RL++C+CY+V
Sbjct: 29 WAFLFLLLIPIITIFGNILVGVSVYLEKRLQNRFNYFLVSLAVSDFLCAILVMPVSTVKMVHVDLTNGWPHQLCLAWYSLDVFFTATTIIHLCTISIDRYVALNNPLRFHQTKRKYSLFIKISISWLIPFGIACPLFLSSLKIETMNQEESSFKGCGPNNAIFIMTAVIVTFILPLLIMMISYILTVKTIRKQTKNLDSFSTNGHRKSRFSQSEIYKKSMPSTSLTTSILNVNSKVCDDLNHSLNQEKLSLL---SIST-------DFSRRSLMSCNNFPTTP-------SKIQENIDGDKETYFDFRGKFSRLSRQMSIPFRKNTLRLHRNSSVNSERLRLCANVLLN-------SRLSVNSRRIATSDLSLRY------------IQKSRKAVQVLGIVFGLFVCCYMPFFVIYLTDFFCVSC--KSITSWMISYSEWIGYSASMMNPVVYHIFNPTFRRTFNRLIRCRCYKV 465
BLAST of GCR027 vs. TrEMBL
Match: A0A1S8WK07 (7 transmembrane receptor (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_09436 PE=3 SV=1) HSP 1 Score: 272.322 bits (695), Expect = 8.137e-81 Identity = 177/506 (34.98%), Postives = 260/506 (51.38%), Query Frame = 2
Query: 173 YVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKR-----YRSLVVQLVCAWIIPFSIACPLFLFALELDKTREH---------------SSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA-NLYSN-----AVASLV-------FKP-KLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMN-LCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHA 1585
Y+ L +IP+ ++WGN VC++V++E LR RFN FLVSLA+SD LCAILVMP+SAW MI N CL+ YS+D+FFTA+TIIHLC+IS+DRY AL+ P G+ R ++SLV ++ +W +PFSIA PLF+FAL+ ++ E S+KGCGP + F+L A VTF +PLIIMT TYVLTVK+L + +A LY+ + +S++ F+P +++ S + R + K + S +++ T L + L + EN P+ + + S N +CG D PS + + + + + F +H + + E L L S R +S+ T +I+ ++AV+ + +LF LFV CY PFF+ Y + C S AE + LEW+GY SM NP+VYH FN FR T++R+ +C C HA
Sbjct: 9 YIALCLIPLGTIWGNICVCLAVYLERRLRHRFNLFLVSLAISDLLCAILVMPVSAWHMIAT---RPQNRILCLVSYSMDIFFTATTIIHLCSISLDRYLALRRPF---GRNRAVPKIFQSLVFRIFMSWFVPFSIAGPLFVFALKWERGDEEFIVTMTPESANITTSKSYKGCGPNDKSFVLTAIGVTFVLPLIIMTATYVLTVKMLRRHMAQVKAIQLYATRPRPVSTSSVLWLRRDNSFRPTEINRSTKAWFRQADQQSTIPKTTKYMPASDSGCDEKTVKTCSLSDPLSYHNRPAENPP--RRIPIGVENPSTQDEASLSGNRVCGKD---PSDKSNDQQSYVKASETLFLTSTAKNDHDISGLELSSNHE--LGLPSQGRRTDISSAQTTTAID--------------RIHSGKRAVRVIAVLFGLFVTCYTPFFIVYTISVVCPQC--RSWAEPAIPHLEWLGYLNSMLNPVVYHSFNSTFRRTFRRIFQCACRTPHEHHA 485
BLAST of GCR027 vs. TrEMBL
Match: A0A074ZZH1 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_02329 PE=3 SV=1) HSP 1 Score: 272.322 bits (695), Expect = 8.733e-81 Identity = 179/506 (35.38%), Postives = 262/506 (51.78%), Query Frame = 2
Query: 173 YVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKR-----YRSLVVQLVCAWIIPFSIACPLFLFALELDKTREH---------------SSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA-NLYSN-----AVASLV-------FKP-KLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMN-LCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHA 1585
Y+ L +IP+ ++WGN VC++V++E LR RFN FLVSLA+SD LCAILVMP+SAW MI N CL+ YS+D+FFTA+TIIHLC+IS+DRY AL+ P G+ R ++SLV ++ +W +PFSIA PLF+FAL+ ++ E S+KGCGP + F+L A VTF +PLIIMT TYVLTVK+L + +A LY+ + +S++ F+P +++ S + R + K + S +++ T L + L + EN P+ + + S N +CG D PS + + + + + F +H L L S+ S +TD SA +T + +I+ ++AV+ + +LF LFV CY PFF+ Y + C S AE + LEW+GY SM NP+VYH FN FR T++R+ +C C HA
Sbjct: 9 YIALCLIPLGTIWGNICVCLAVYLERRLRHRFNLFLVSLAISDLLCAILVMPVSAWHMIAT---RPQNRILCLVSYSMDIFFTATTIIHLCSISLDRYLALRRPF---GRNRAVPKIFQSLVFRIFMSWFVPFSIAGPLFVFALKWERGDEEFIVTMTPESANITTSKSYKGCGPNDKSFVLTAIGVTFVLPLIIMTATYVLTVKMLRRHMAQVKAIQLYATRPRPVSTSSVLWLRRDNSFRPTEINRSTKAWFRQADQQSTIPKTTKYMPASDSGCDEKTVKTCSLSDPLSYHNRPAENPP--RRIPIGVENPSTQDEASLSGNRVCGKD---PSDKSNDQQSYVKASETLFLTSTAKNDHDISG----------LELSSNHELGLPSQGRRTDISSA------QTTTAIDRIHSGKRAVRVIAVLFGLFVTCYTPFFIVYTISVVCPQC--RSWAEPAIPHLEWLGYLNSMLNPVVYHSFNSTFRRTFRRIFQCACRTPHEHHA 485
BLAST of GCR027 vs. TrEMBL
Match: A0A4S2M3D3 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002997 PE=3 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 1.705e-78 Identity = 176/506 (34.78%), Postives = 260/506 (51.38%), Query Frame = 2
Query: 173 YVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKR-----YRSLVVQLVCAWIIPFSIACPLFLFALELDKTREH---------------SSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA-NLYSN-----AVASLV-------FKP-KLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMN-LCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHA 1585
Y+ L +IP+ ++WGN VC++V++E LR RFN FLVSLA+SD LCAILVMP+SAW MI N CL+ YS+D+FFTA+TIIHLC+IS+DRY AL+ P G+ R ++SLV+++ +W +PFSIA PLF+FAL+ ++ E S+KGCGP + F+L A VTF +PLIIMT TYVLTVK+L + +A LY+ + +S++ F+P + + S + R + K + +++ T L + L + E P+ + + S N + G D PS + + + + + F +H L L S+ S +TD SA +T + +I+ ++AV+ + +LF LFV CY PFF+ Y + C S AE + LEW+GY SM NP+VYH FN FR T++R+++C C HA
Sbjct: 9 YIALCLIPLGTIWGNICVCLAVYMERRLRHRFNLFLVSLAISDLLCAILVMPVSAWHMIAT---RPQNRILCLVSYSMDIFFTATTIIHLCSISLDRYLALRRPF---GRNRALPKIFQSLVLRIFMSWFVPFSIAGPLFVFALKWERGDEEFNVTMTPEAANITISKSYKGCGPNDKSFVLTAIGVTFVLPLIIMTATYVLTVKMLRRHMAQVKAIQLYATRPRPVSTSSVLWLRRDNSFRPTETNRSTKAWFRQTDQQTTIPKTAKYMPPSDCGCDEKTVKTCSLSDPLSYHNRPAEKPR--TRIPIGVENPSTQDEASLSGNRVSGKD---PSDRSNDQQSYIKASETLFLTSTAKTDHDISG----------LELSSNHELGLPSQGRRTDISSA------QTTTAIDRIHSGKRAVRVIAVLFGLFVTCYTPFFIVYTISVVCPQC--RSWAEPAIPHLEWLGYLNSMLNPVVYHSFNSTFRRTFRRILQCACRTPHEHHA 485
BLAST of GCR027 vs. Ensembl Cavefish
Match: drd2b (D(2) dopamine receptor A [Source:NCBI gene;Acc:103035621]) HSP 1 Score: 150.984 bits (380), Expect = 1.076e-39 Identity = 135/489 (27.61%), Postives = 216/489 (44.17%), Query Frame = 2
Query: 116 DNGTFPIFNMSFHSRYNWAYVGLFIIPML--SMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
DNGT + +++ + Y + + ++ ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L TR+ S C N F++ ++I++F++P II + YV +L +RK A +P L L K P T V G ++S + ++ VN L ++ + H E P D+ K +D QT P+ SF E Q N K+ T T K +K K ++ + +KA Q L I+ +F+IC+LPFF+ +++ C V +M W+GY S NPI+Y FN FR + +++ C
Sbjct: 15 DNGTEAFNSTGCEAKHQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWRFSKIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISVVWVLSFAISCPL-LFGLNNTATRDDSV---CEIANPAFVVYSSIMSFYVPFIITLLVYVQIYVVLRKRRKRVNTKRNCQK-ADAEPQPPLKQLLIKEVVQPGTGVEM-----GLMTSTSPPEKMKLAAPPAVNLLATQSPSHASPLHEEWQP--------------------HDDEKNGHAKD--AQT-PKETKSF-ETQALPNG--KTRTTVT---------------KTMSKRKMSQH------------------KEKKATQMLAIVLGVFIICWLPFFITHILKTHCTSCYVPL---EMYNAFTWLGYVNSAVNPIIYTTFNVEFRKAFMKILHC 423
BLAST of GCR027 vs. Ensembl Cavefish
Match: drd2a (D(2)-like dopamine receptor [Source:NCBI gene;Acc:103036974]) HSP 1 Score: 151.369 bits (381), Expect = 1.198e-39 Identity = 128/476 (26.89%), Postives = 222/476 (46.64%), Query Frame = 2
Query: 158 RYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEAN-LYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDS-EFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSH-QRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
+YN+ + L ++ + ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + WI+ F+I+CPL LF L ++R+ + C N F++ ++IV+F++P II + YV +L +RK + ++ A + ++L K T K+ + + N N ++ I +VN+ D + E N PL +T + L + + E + T+P+ + T + + V E ++ Q S K NK K + + +KA Q L I+ +F+IC+LPFF+ ++V+ ++ + ++ T W+GY S NPI+Y FN FR + +++ C
Sbjct: 31 QYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWILSFAISCPL-LFGLNNTESRDDAL---CVIANPAFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVSTKRTFPSSTA------ERGTTLKKCTHPDDVKLCT--VIVKSNGNFPVNNKNVIFIKEVVNNADDVQADEVTNPE-----PLNQRTLEQTGASQHGLLLVSTHS------ETEVLPTVPEAPIKPSRNGNTGD----APRVTKAFETQVSPSGKTQSSVKSFNKRKFSQ------------------QKEKKATQMLAIVLGVFIICWLPFFITHIVNTYYNV------PAELYTAFTWLGYVNSAVNPIIYTTFNIEFRKAFIKILHC 447
BLAST of GCR027 vs. Ensembl Cavefish
Match: drd3 (dopamine receptor D3 [Source:NCBI gene;Acc:103024755]) HSP 1 Score: 144.821 bits (364), Expect = 3.509e-37 Identity = 127/475 (26.74%), Postives = 220/475 (46.32%), Query Frame = 2
Query: 173 YVGLFIIPMLSM-WGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPL---KIHGQKRYRSLVVQLVCAWIIPFSIACPL-FLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRS---FKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
Y L+ + +L++ +GN LVC++V E L+ NY +VSLA+SD L A LVMP W + YLE + W C I+ +LDV ++I++LC ISIDRY A+ P+ H ++ S+++ V WI+ F+++CPL F F D C N F++ +++V+F++P ++ + YV L +RK+ S V +P + L + TR + +S ++N NE++ + R + + C L K R VEN+ + N S+ + + +T + E ++ +S C V E +S+ R+ + + + T A Y +R +KA Q L I+ +F+IC+LPFFV ++++ + C + ++ + W+GY S NP++Y FN FR + +++ C
Sbjct: 57 YAMLYSLLILAIVFGNVLVCMAVLREKSLQTTTNYLVVSLAVSDLLVASLVMP---WAV----YLEVVGGAWLFSRLYCNIFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHSSRKRVSVMIATV--WILAFAVSCPLLFGFNTTDDPL-------VCSISNPDFVIYSSVVSFYLPFVVTLLVYVRIYVFLRKRRKKITFRQTSGEVQQGSAQPSAETCLQEETRK-VRRDLSPIRINVVNESTEKVVRPRLLSGC----------------------LRRKRPRTVPVENSLLPPMDLQNYC-SISQASFARTEQEPNREEEEGREEDQVTVRS---CEVKE-----ISNGRTHTTLRPAPRVTTRASQARYRSIH---------SREKKATQMLAIVLGVFLICWLPFFVTHILNTHCRSCYI---PPELYSAFTWLGYVNSALNPVIYTTFNIEFRRAFIKILTC 471
BLAST of GCR027 vs. Ensembl Cavefish
Match: htr2ab (5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-120215-60]) HSP 1 Score: 124.79 bits (312), Expect = 2.998e-30 Identity = 74/200 (37.00%), Postives = 115/200 (57.50%), Query Frame = 2
Query: 164 NWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLV-VQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQ 742
NW + + + ++++ GN LV ++V +E L+ NYFL+SLA++D L +LVMP+S ++ NY +W C IW LDV F+ ++I+HLC IS+DRY A++NP++ H + R+ V++ AW I I+ P+ + L H+ C + F+LI + V FF+PLIIM VTY LT+ L Q
Sbjct: 81 NWVALLILLAIVITVTGNILVIMAVSLERKLQNATNYFLMSLAITDMLLGLLVMPVSMVTILYNY-------RWPFPFVLCPIWIYLDVLFSTASIMHLCAISLDRYIAIRNPIQ-HSRSNSRARARVKIAAAWTISVGISMPVPVIGLYDHSKVFHNG--SCQLKEDNFVLIGSFVAFFVPLIIMVVTYFLTISALQSQ 270 HSP 2 Score: 60.8474 bits (146), Expect = 1.872e-9 Identity = 31/90 (34.44%), Postives = 49/90 (54.44%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLE---WMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
I+ +KA + LG++F LFVI + PFFV + +C + M+ L W+GY S NP++Y FN +R + R ++C+ YR
Sbjct: 327 ISNEQKASKVLGVVFFLFVIMWCPFFVT---NVLLVVCDSACDPSLMIGLLNVFVWVGYLSSAVNPLIYTLFNKTYRAAFARYLRCR-YR 412
BLAST of GCR027 vs. Ensembl Cavefish
Match: adra2a (adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750]) HSP 1 Score: 119.783 bits (299), Expect = 5.768e-29 Identity = 112/455 (24.62%), Postives = 182/455 (40.00%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPIS-AWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPST---KVMSEKKLNG---KNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQ--QKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
GN L I+V+ L+ N FLVSLA +D L A LVMP S A +++ +Y + WC I+ +LDV F ++I HLC IS+DRY ++ ++ + ++ R + ++ W+I I+ P E + + S + ++ ++I+ + I +FF+P IIM + Y+ +I + TRTP K EKK NG + N A + VN++D E E+ + +H P +K R S Q P ++ RE + TK+ WK NR ++ L ++ +F+IC+ PFF Y + + C V+ T + F W GY S NPI+Y FN FR +++++
Sbjct: 29 GNLLAVIAVFTSRALKAPQNLFLVSLASADILVATLVMPFSLANELMGYWYFGPV---WCKIYLALDVLFCTASIAHLCAISLDRYWSITRAVEYNLKRTPRRIKCVILVVWVIAAVISFPPLTIMKEDEPINDPPSCQI--NKDKWYIISSCIGSFFLPCIIMVLVYIRIYQIAKSR-----------------------------TRTPPGDRRKRDDEKKENGHCHERLNGDAANGNDKDDKGDVNAVDME--ESSSSDHKVTNPCASKKKRAKGKTKLS-------------------QIKPGDDINKRENANRGTKSSRWKGRQ----------------------------------------------NREKRFTFVLAVVIGVFMICWFPFFFTYTLRALCESCCVNET---LFKFFFWFGYCNSSLNPIIYTIFNNDFRRAFKKIL 379
BLAST of GCR027 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004593.1 (pep scaffold:Pmarinus_7.0:GL476854:168999:207459:1 gene:ENSPMAG00000004184.1 transcript:ENSPMAT00000004593.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.783 bits (299), Expect = 8.119e-30 Identity = 69/179 (38.55%), Postives = 109/179 (60.89%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKG-CGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQ 742
GN LV ++VW+E L+ NYFL+SLA++D L + VMPIS ++ N + + C +W LDV F+ ++I+HLC IS+DRY A+K P++ H + RS ++++ W I IA P+ + L+ ++H G C FI+ ++V+FF+PL+IM V YVLT+++L Q
Sbjct: 21 GNLLVILAVWLEKKLQTATNYFLMSLAVADLLVGLTVMPISVINILYNMRWP-LPCEMCPVWVFLDVLFSTASIMHLCAISLDRYIAIKRPIQ-HSRFNSRSKTLLKITAVWAISIGIASPIPVLGLQ---DQQHVFVNGACILNIQNFIIYGSVVSFFLPLLIMVVIYVLTIRLLRGQ 194 HSP 2 Score: 67.781 bits (164), Expect = 1.964e-12 Identity = 37/99 (37.37%), Postives = 57/99 (57.58%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFF--KICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQ 1597
++ R+A + LGI+F LF++ + PFFV + +CSV + A+ M F+ W+GY S NP+VY FN +R ++R + C R RH SSS+
Sbjct: 275 LSNERRASKVLGIVFTLFLVMWCPFFVTNVTSALCPESLCSVEAMAKLMDIFV-WVGYVSSGVNPLVYTLFNQTYRQAFRRYVACDFRRA--RHRSSSK 370
BLAST of GCR027 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006953.1 (pep scaffold:Pmarinus_7.0:GL477632:7596:14007:1 gene:ENSPMAG00000006283.1 transcript:ENSPMAT00000006953.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 108.227 bits (269), Expect = 1.122e-25 Identity = 65/187 (34.76%), Postives = 110/187 (58.82%), Query Frame = 2
Query: 203 SMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRS-LVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA 760
++ GN LV ++V +E L+ NYFL+SLA++D L ILVMPIS ++ + + C +W LDV F+ ++I+HLC IS+DRY A+K P++ H + R+ +++++ W+I I+ P+ + L+ D ++ C + FI+ ++ +FF+PLIIM +YV T ++L Q E
Sbjct: 38 TIAGNVLVILAVSLEKKLQTATNYFLMSLAVADMLVGILVMPISLLNILYGFKWP-LPLSLCPVWIYLDVLFSTASIMHLCAISLDRYIAIKKPIE-HSRFNSRTKALLKILAVWVISVGISMPVPVLGLQ-DLAYVYTD-GSCQMNISDFIIYGSLSSFFLPLIIMVASYVSTTRVLRQQALLCEG 220 HSP 2 Score: 55.0694 bits (131), Expect = 2.567e-8 Identity = 28/87 (32.18%), Postives = 43/87 (49.43%), Query Frame = 2
Query: 1307 INRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSS----TAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
I ++A + LGI+FLLFV + PFF+ + +C + +L W+GY S NP+VY FN +R + R + C
Sbjct: 309 ITNEQRASKVLGIVFLLFVGMWCPFFIT---NVLSALCPADACNRHAMAALLDVFVWVGYVSSGVNPLVYTLFNRTYRQAFARYIAC 392
BLAST of GCR027 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009127.1 (pep scaffold:Pmarinus_7.0:GL478629:43196:44446:-1 gene:ENSPMAG00000008256.1 transcript:ENSPMAT00000009127.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 96.2857 bits (238), Expect = 9.945e-22 Identity = 56/173 (32.37%), Postives = 102/173 (58.96%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISA-WKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTY 712
+ +++GNS V ++ +E L+ NY + SLA++D L +ILV+P++A ++++D + T+ C I+ +LDV S+I+HLC I++DRY A+ NP+ ++ R V+ + W++ FSI+ P L + + ++ K Q+ + + +T F+IPLI+M V Y
Sbjct: 48 LCAIFGNSCVIAAIALERTLQNVANYLIGSLAVTDLLVSILVLPMAALYQVLDRW---TLGQVVCDIFIALDVLCCTSSILHLCVIALDRYWAITNPIDYVNKRTPRRAVIMISLTWLVGFSISIPPMLGWRTPEDRADPNACKIS--QDHGYTIYSTFGAFYIPLILMLVLY 215
BLAST of GCR027 vs. Ensembl Sea Lamprey
Match: adra2c (adrenoceptor alpha 2C [Source:NCBI gene;Acc:266752]) HSP 1 Score: 95.9005 bits (237), Expect = 2.453e-21 Identity = 67/216 (31.02%), Postives = 107/216 (49.54%), Query Frame = 2
Query: 101 GAFKMDNGTFPIFNMSFHSRYNWAY-----VGL----FIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDK-TREHSSFKGCG-PQNAYFILIATIVTFFIPLIIMTVTYV 715
GA NGT + W Y +GL I+ +++GN LV I+V L+ N FLVSLA +D L A LV+P S + + Y+ WC I+ +LDV F S+I+HLC IS+DRY ++ ++ + ++ R + +V W I +I+ P + + ++ +E C N ++IL + I +FF P +IM + Y
Sbjct: 30 GATNSSNGT--------DEKLGWEYSVLAGLGLSSLVLILVFATVFGNCLVIIAVLTRPSLKAPQNLFLVSLATADILVATLVIPFSLFNELMGYWY--FGRVWCEIYLALDVLFCTSSIVHLCAISLDRYWSVSQAVEYNIKRTPRRIKRIIVIVWFIAIAISLPPLISMNQKNRQQQEEVGRPNCELNTNTWYILGSCIGSFFAPCLIMVLVYA 235 HSP 2 Score: 56.9954 bits (136), Expect = 6.151e-9 Identity = 29/84 (34.52%), Postives = 44/84 (52.38%), Query Frame = 2
Query: 1313 RSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTA--EKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQ 1558
R R+ L ++ +FVIC+ PFF Y + +CS S A E + F W GY S NP++Y FN FR +++++ Q
Sbjct: 377 RERRFTFVLSVMIGVFVICWFPFFFTYSLS---ALCSPESCAIPETLFKFFFWFGYCNSCLNPVIYTVFNRDFRRAFKKILCMQ 457
BLAST of GCR027 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008360.1 (pep scaffold:Pmarinus_7.0:GL477173:168532:170490:1 gene:ENSPMAG00000007563.1 transcript:ENSPMAT00000008360.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.2781 bits (225), Expect = 8.401e-20 Identity = 61/207 (29.47%), Postives = 102/207 (49.28%), Query Frame = 2
Query: 185 FIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGP----------------QNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAE 757
FII +++++GNSLV I+V+ L+ N FLVSLA +D L A LVMP S + Y++ WC ++ +LDV F S+I+HLC IS+DRY ++ ++ + ++ R + +V W+I I+ P + +G G + +++L + +FF P +IM + Y +I V + A
Sbjct: 42 FII-LVTIFGNSLVAIAVFTSKSLKAAQNLFLVSLAAADILVATLVMPFSLANELMGYWV--FGSFWCEMYLALDVLFCTSSIVHLCAISLDRYWSVTQAVRYNMKRTPRRVKRAIVIVWVIAALISFPPLVGTGRPPANIHRHRHQGSGRNASSSPSSVLPTCKLNEETWYVLSSCTASFFTPCLIMLLVY---ARIYQVAKGRAR 242 HSP 2 Score: 51.6026 bits (122), Expect = 3.434e-7 Identity = 26/80 (32.50%), Postives = 41/80 (51.25%), Query Frame = 2
Query: 1313 RSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVS-STAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
R ++ L ++ +FV C+ PFF +Y + KIC S E + F W GY S NP++Y FN FR ++ ++
Sbjct: 387 REKRFTFVLAVVMGVFVACWFPFFFSYSLT---KICEASCKPPEYLFKFFFWCGYCNSSLNPLIYTVFNQDFRRAFKNIL 463
BLAST of GCR027 vs. Ensembl Nematostella
Match: EDO47359 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMJ9]) HSP 1 Score: 87.8113 bits (216), Expect = 1.281e-18 Identity = 54/201 (26.87%), Postives = 106/201 (52.74%), Query Frame = 2
Query: 182 LFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMI-DNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKI-----LYVQRKEAEANL 766
+ I+ +L++ GN LVC SV+ LR NY +VSLA+SD L L +P +++ + + + + C W +D+ + +++++L IS DR A+K PL+ + + ++ ++ WI S A FL +E + +++ CG + +I + + FF PL+I+ + Y + +++ L VQ+++ + L
Sbjct: 30 IVIVMLLTIMGNLLVCYSVFYYRRLRSPTNYLVVSLAVSDLLVGTLSLPFRLAQLLNEENWPSHLGREGCQFWIWVDMLCSGASMVNLAGISFDRLLAIKQPLRYREKMTSKRALILILVVWIYAASCA---FLSFVEWEGESTIAAYPQCGIRARVYITLMALAAFFCPLLIVIICYGMVLQVAIRHALQVQKEKEQIAL 227
BLAST of GCR027 vs. Ensembl Nematostella
Match: EDO28603 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T607]) HSP 1 Score: 82.0333 bits (201), Expect = 5.403e-17 Identity = 55/193 (28.50%), Postives = 94/193 (48.70%), Query Frame = 2
Query: 188 IIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTRE----HSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEA 754
+I L ++GN LVC++++ LR NY + SLA+SD L A L MP + + + + C W +D + ++I +L I+IDRY L P + R + ++ W+ F IA +L L + ++SF C + Y+ A ++FF+PL+++ + Y + K V RK+A
Sbjct: 28 VILFLDLFGNLLVCVAIYRYRRLRSVTNYLIGSLAVSDLLVACLSMPFRIYHTL-HLMCWDLGLSVCKFWIFVDALCSGASICNLSLIAIDRYLVLSCPFSYREKMRKPRGFIAILAVWLYAFVIA------SLSLTEPWSPDGFNASFPACAKMDKYYYAFAITMSFFLPLVVLIIAYSMVFK---VARKQA 210
BLAST of GCR027 vs. Ensembl Nematostella
Match: EDO40999 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5M0]) HSP 1 Score: 81.6481 bits (200), Expect = 8.448e-17 Identity = 55/193 (28.50%), Postives = 94/193 (48.70%), Query Frame = 2
Query: 188 IIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTRE----HSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEA 754
+I L ++GN LVC++++ LR NY + SLA+SD L A L MP + + + + C W +D + ++I +L I+IDRY L P + R + ++ W+ F IA +L L + ++SF C + Y+ A ++FF+PL+++ + Y + K V RK+A
Sbjct: 39 VILFLDLFGNLLVCVAIYRYRRLRSVTNYLIGSLAVSDLLVACLSMPFRIYHTL-HLMCWDLGLSVCKFWIFVDALCSGASICNLSLIAIDRYLVLSCPFSYREKMRKPRGFIAILAVWLYAFVIA------SLSLTEPWSPDGFNASFPACAKMDKYYYAFAITMSFFLPLVVLIIAYSMVFK---VARKQA 221
BLAST of GCR027 vs. Ensembl Nematostella
Match: EDO49367 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG65]) HSP 1 Score: 74.7146 bits (182), Expect = 9.015e-15 Identity = 48/170 (28.24%), Postives = 87/170 (51.18%), Query Frame = 2
Query: 212 GNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLT 721
GNSLVC+++ ++ LR N+F+ SLA++D L ++ +P ++++ C +W D+ A++I +L IS+DRY + P + H + ++ ++ +V WI +I L + K H + C N F +A IV F +PL+I+ + YV+
Sbjct: 13 GNSLVCLAICLDHRLRNSTNWFIASLAVADLLYGLIGLP---FRIVQTSGTRVFTLNECFLWIWADMVCAAASIANLAVISVDRYLKITKPFQYHIRMTHKRALLAVVAVWIYS-AILASLSIMPWPGAKG-VHLFEQSCTNLNQVFYTVANIVAFILPLLILVLNYVMV 177
BLAST of GCR027 vs. Ensembl Nematostella
Match: EDO44740 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUQ8]) HSP 1 Score: 74.7146 bits (182), Expect = 1.262e-14 Identity = 64/246 (26.02%), Postives = 110/246 (44.72%), Query Frame = 2
Query: 188 IIPMLSMWGNSLVCISVWVEVGLRKRF-NYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIAC-PLFLFALELDKTREHSSFKGCG-PQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSI 916
+I + ++ GN LV + LR NY++VSLA SD L A LV+P + I + + T C +W +L + +II+LC +++DR+ L PL+ R +V +VC W AC P+ + D+ ++ F C P ++++ I F +P+I M V + L KI ++ + KL S++ T S + + NG+ S +++I
Sbjct: 5 LIIIFALLGNILVVYAFCNYHRLRANVTNYYIVSLAFSDILTAGLVVPFELDQTIRDG-IWTHGRITCQLWTTLYLLVVPGSIINLCAVTLDRFIVLHMPLRYTTIITPRKAIVAIVCLWTYALVTACLPVLGWK---DQNYDYILFNACYFPLLQEYVMLINITNFLLPMIFMAVFWSLIFKIAKKHQRRVK---------------KLERSMSMVETTMSLSINGNEAQNGRPSMSEGGKKKTI 231
BLAST of GCR027 vs. Ensembl Medaka
Match: drd2a (dopamine receptor D2 [Source:NCBI gene;Acc:101164579]) HSP 1 Score: 152.14 bits (383), Expect = 9.638e-40 Identity = 137/509 (26.92%), Postives = 229/509 (44.99%), Query Frame = 2
Query: 116 DNGTFPIFNMSFHSRYNWAYVGLFIIPML--SMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQ-KRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEF-KETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQED--------QYKQTLPQRQ---------VSFREQQKTKNHYWKSNTVCTVLENPLALLSH--QRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
DNGT+ N ++ + Y + + ++ ++GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + +W C I+ +LDV ++I++LC ISIDRY A+ P+ + + R + V + W++ F+I+CPL LF L TR+ S C N F++ ++IV+F++P II + YV +L +RK KPK + + T + +K + ++ M +S + S VN F K+ N +E +N GS + L + ++Q +P + E QK + K+ VL +P +++ Q + KT+T K K+ + +KA Q L I+ +F+IC+LPFF+ ++++ C V + +M W+GY S NPI+Y FN FR + +++ C
Sbjct: 15 DNGTWSFNNTEPLPKHTYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMP---WVV----YLEVVG-EWRFSKIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWVMSFAISCPL-LFGLNNTATRDESL---CVIANPAFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVNT------------KPK--QRICQAADTDGATSLKDKCTHPEDVRLCTMIVKS-NGSFPVNKKKVIFIKDVANDGE--------------DLELDELNNSGSSQKQKQLTQSVLGDTPATSHQQLMPSKANASPTSTPPTPPEEGQKAE----KNEDTTDVLTDPAPIVAKAFQTQALPNGKTQTS--------VKTMSKRKISQQKEKKATQMLAIVLGVFIICWLPFFITHILNTHCTKCKVPA---EMYNAFTWLGYVNSAVNPIIYTTFNVEFRKAFIKILHC 467
BLAST of GCR027 vs. Ensembl Medaka
Match: drd3 (dopamine receptor D3 [Source:NCBI gene;Acc:101163209]) HSP 1 Score: 139.043 bits (349), Expect = 3.374e-35 Identity = 125/478 (26.15%), Postives = 216/478 (45.19%), Query Frame = 2
Query: 173 YVGLFIIPMLSM-WGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQW------CLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVC-AWIIPFSIACPL-FLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKV-MSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTV---CTVLENPLALLSHQRSF----KMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKC 1555
Y L+ + +L++ +GN LVC++V E L+ NY +VSLA++D L A LVMP W + YLE + W C I+ +LDV ++I++LC ISIDRY A+ P+ + R V ++ W++ F+++CPL F F D C N F++ +++V+F++P I+ + Y+ L ++RK V P + + L + TP K +S ++ ++ SS + S+ + C L + +T + + P+ N+ + S CG L Q QV EQ + ++ + + C V E LS+ R+ +S+ + + + R +KA Q L I+ +F+IC+LPFFV ++++ + C + T W+GY S NP++Y FN FR + +++ C
Sbjct: 39 YAMLYSLLILAIVFGNVLVCLAVLRERSLQTTTNYLVVSLAVADLLVASLVMP---WAV----YLEVVGGAWLFNRLYCNIFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHCSRKRVFAMIATVWVLAFAVSCPLLFGFNTTDDPMV-------CSISNPDFVIYSSVVSFYLPFIVTLLVYIRIYVFLRMRRKRIAFGQARGKVQPGSTHPSVETCLQE--ETPKAKQDLSPIRIKVQSVESSGTSKPSLLSGC----LWRKRPKTGPAQNSGLPPV----DMQNYC-SISHASCGRTEFD-----------LEQGQV---EQDASDSNQLELPPIRMNCEVKE-----LSNGRTHTSLRPISHSQNNPRFRSMHA-------------REKKATQMLAIVLGVFLICWLPFFVTHILNTHCRTCQIPPALYGAFT---WLGYVNSALNPVIYTTFNIEFRRAFIKILSC 456
BLAST of GCR027 vs. Ensembl Medaka
Match: ENSORLT00000042787.1 (alpha-2B adrenergic receptor-like [Source:NCBI gene;Acc:101155866]) HSP 1 Score: 137.117 bits (344), Expect = 1.504e-34 Identity = 112/458 (24.45%), Postives = 203/458 (44.32%), Query Frame = 2
Query: 197 MLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPIS-AWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQN-AYFILIATIVTFFIPLIIMTVTYVLTVKI----LYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVS-STAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLM 1549
+L++ GN LV I+V + LR N FLVSLA +D L A++V+P S A++++ + +I WC I +LDV F ++I+HLC I++DRY ++ P+ + R + +V W+I ++ P L+ DK + C P + ++IL +TI +FF P +IM + Y+ +I ++ E + Y A K S S+K + + + + ++ T C + ++ K E+ E PL + N + +L + ED + + + ++ + V ++P ++ + K S+ TK T++ + INR ++ L ++ +FV+C+ PFF +Y + +C + + F W GY S NPI+Y FN FR ++R++
Sbjct: 39 ILTIVGNILVIIAVLMSRSLRGPQNLFLVSLAAADILVALIVVPFSMAYELLGCWVFSSI---WCEIHKALDVLFCTASIVHLCAIALDRYLSISRPVSYGTTRSRRRIKSAIVMVWLIAAVVSFPPLLYLDTKDKVKGK-----CEPDDKPWYILYSTIGSFFAPCVIMILVYIRIYQIAKRHMHCPPGEKRRSFYGAATDDTEMK--------------SLPEESQKDVGQRAPAAPELSLTTVHTDC---AQWNDKKPAESPT--EGPPLFSTAVPN-----------AARDLPKAEGEDAVHTSSSESDTELQSIEEGDRAGGGGSPKAQV-QSPTC--RYKNTIKTSSGTKLLPEDTAKTQETPISRHKAMINREKRFTLVLAVVMGVFVVCWFPFFFSYSLK---AVCPEKYQVPDPLFRFFFWSGYCNSCLNPIIYTIFNRDFRTAFKRIL 452
BLAST of GCR027 vs. Ensembl Medaka
Match: ADRA2C (adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:HGNC:283]) HSP 1 Score: 135.576 bits (340), Expect = 3.487e-34 Identity = 125/497 (25.15%), Postives = 217/497 (43.66%), Query Frame = 2
Query: 89 TKFLGAFKMDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPIS-AWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQN-AYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETEN-HNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVS-STAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYR 1567
T+ LG F T S + A + F+I + ++ GN LV I+V L+ N FLVSLA +D L A LVMP S A +++ +Y + WC I+ +LDV F S+I+HLC IS+DRY ++ ++ + ++ R + ++ W++ I+ P + +D+ + SS C + ++IL ++I +FF P +IM + Y+ ++ + + KPK P +E NG ++ SS +H E EN H H TP T + + S + K PQRQ S R ++ K+ + K + + ++SNK+ S ++ ++ R ++ L ++ +FV+C+ PFF +Y + + +C S + + F W+GY S NP +Y FN FRH +Q+++ C+ ++
Sbjct: 12 TQRLGNFTPSGNTTLDGGYSLAAVAGIAALVSFLI-LFTVVGNILVVIAVLTSRALKAPQNLFLVSLATADILVATLVMPFSLANELMGYWYFGKV---WCGIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRIKCTILIVWLVSAFISSPPL---VSIDRNNDISSQPQCELNDETWYILSSSIASFFAPCLIMILVYIRIYQVAKTRTRSMSEK-----------KPK-----------PDGVTQTE---NGLSKVSSPLH-----------------GEAENGHCHCPPTPSQRTVTTGPQTQEVDVEESSS---------SEGKGHNPQRQDSQRARKARKSSFSKHSAHIS---------------RVSNKSMDLFASRRKRRRSSFARKKVSQAREKRFTFVLAVVMGVFVMCWFPFFFSYSL---YGVCRDSCRIPDPLFKFFFWIGYCNSSLNPAIYTIFNRDFRHAFQKIL-CKAWK 431
BLAST of GCR027 vs. Ensembl Medaka
Match: adra2a (adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750]) HSP 1 Score: 133.265 bits (334), Expect = 1.422e-33 Identity = 116/470 (24.68%), Postives = 192/470 (40.85%), Query Frame = 2
Query: 176 VGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPIS-AWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKN--ENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFI 1576
VG+ I L ++GN LV I+V+ LR N FLVSLA +D L A LVMP S A +++ +Y + WC I+ +LDV F ++I HLC IS+DRY ++ ++ + ++ R + +V W+I I+ P L +E + E K ++++ + I +FF+P IIM + Y V+I + +K A L ++ + + +KLNG+ E + R + VN D E + +H + K+ + K L + + PQR+ Q K WK NR ++ L ++ +FV+C+ PFF Y++ +CS + F W GY S NPI+Y FN FR +++++ C+ R ++
Sbjct: 23 VGVMI--SLIVFGNVLVVIAVFTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMGFWYFGKV---WCEIYLALDVLFCTASIAHLCAISLDRYWSITQAIEYNLKRTPRRIKSIIVIVWVIAAVISFPP-LITMEKENGSESPVCK--INDEKWYVISSCIGSFFLPCIIMVLVY---VRIYQIAKKRTRAPPGDRQQKGLSGPGAAAAGQRENGVGEPDDGLCHEKLNGEQDVELKEGVERGADEAKVEVNGGDMEESSSSDHKADHPCSIPKKSAKG----------------KTRLSQVKPGDADPQRRA-----QSAKASRWKGRQ----------------------------------------------NREKRFTFVLAVVIGVFVVCWFPFFFTYMLK---TLCSSCYVPTALFNFFFWFGYCNSALNPIIYTIFNHDFRRAFKKIL-CRERRKYL 410
BLAST of GCR027 vs. Planmine SMEST
Match: SMESG000000740.1 (SMESG000000740.1) HSP 1 Score: 1005.36 bits (2598), Expect = 0.000e+0 Identity = 496/496 (100.00%), Postives = 496/496 (100.00%), Query Frame = 2
Query: 113 MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 1600
MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR
Sbjct: 1 MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 496
BLAST of GCR027 vs. Planmine SMEST
Match: SMESG000000740.1 (SMESG000000740.1) HSP 1 Score: 982.245 bits (2538), Expect = 0.000e+0 Identity = 486/486 (100.00%), Postives = 486/486 (100.00%), Query Frame = 2
Query: 143 MSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 1600
MSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR
Sbjct: 1 MSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDKTREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYTKKKETEKQLKQINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSSQR 486
BLAST of GCR027 vs. Planmine SMEST
Match: SMESG000065390.1 (SMESG000065390.1) HSP 1 Score: 334.724 bits (857), Expect = 1.063e-108 Identity = 199/475 (41.89%), Postives = 276/475 (58.11%), Query Frame = 2
Query: 167 WAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDK-TREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEA-----NLYSNAVASLVFKPKL-SSSLAKFTRTPSTKVMSEKKLNGKNENSSAMHRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMSNKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRV 1570
WA++ L +IP+++++GN LV +SV++E L+ RFNYFLVSLA+SDFLCAILVMP+S KM+ HQ CL WYSLDVFFTA+TIIHLCTISIDRY AL NPL+ H KR SL +++ +W+IPF IACPLFL +L+++ +E SSFKGCGP NA FI+ A IVTF +PL+IM ++Y+LTVK + Q K ++ + S S ++K + S+SL ++KV + + E S + SIST D + + N+F TP + EN + + + + ++P R+ + R + + + + VL N R S + T + S Y I +SRKAVQ LGI+F LFV CY+PFFV YL DFF C S M+++ EW+GYS SM NP+VYH FNP FR T+ RL++C+CY+V
Sbjct: 29 WAFLFLLLIPIITIFGNILVGVSVYLEKRLQNRFNYFLVSLAVSDFLCAILVMPVSTVKMVHVDLTNGWPHQLCLAWYSLDVFFTATTIIHLCTISIDRYVALNNPLRFHQTKRKYSLFIKISISWLIPFGIACPLFLSSLKIETMNQEESSFKGCGPNNAIFIMTAVIVTFILPLLIMMISYILTVKTIRKQTKNLDSFSTNGHRKSRFSQSEIYKKSMPSTSLTTSILNVNSKVCDDLNHSLNQEKLSLL---SIST-------DFSRRSLMSCNNFPTTP-------SKIQENIDGDKETYFDFRSKFSRLSRQMSIPFRKNTLRLHRNSSVNSERLRLCANVLLN-------SRLSVNSRRIATSDLSLRY------------IQKSRKAVQVLGIVFGLFVCCYMPFFVIYLTDFFCVSC--KSITSWMISYSEWIGYSASMMNPVVYHIFNPTFRRTFNRLIRCRCYKV 465
BLAST of GCR027 vs. Planmine SMEST
Match: SMESG000032679.1 (SMESG000032679.1) HSP 1 Score: 326.635 bits (836), Expect = 3.551e-105 Identity = 192/496 (38.71%), Postives = 287/496 (57.86%), Query Frame = 2
Query: 158 RYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDK--------------------TREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAM----HRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMS-NKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRV 1570
RY W ++GL IIP+ ++WGN+LVC+SV++E L+ RFN+FLVSLA+SD LCA+LVMP+SAW M+ N ++ CL WYSLDVFFT++TIIHLC+IS+DRY L NPLK H + SL +++ AW+IPF IACPLF+FAL LD +++ S+KGCGP N YFI+I+T++TF +PL IM VTY+LTV + Q +A NLY N ++ S L + T ++ ++E + N+ S +M + +S +NS DS K F++ + +N F + ++ P+ + P++ ++ ++Q + ++S N + + ++S K ++ + + ++ L +N +KAVQ LGILF LF++CYLPFFV YL+DFF C + +++ EW+GYS SM NPIVYH FNP FR+T+ RLM+C+CY+V
Sbjct: 29 RYQWPFLGLLIIPLCTIWGNALVCVSVFIEKRLQNRFNFFLVSLAISDLLCALLVMPVSAWNMVRNNNFTSVPRGICLAWYSLDVFFTSTTIIHLCSISLDRYFVLNNPLKYHNTRIRSSLPLKISIAWLIPFCIACPLFIFALRLDHMAGNNRNSVPESGWLSNETISQQLDSYKGCGPHNVYFIIISTVITFVLPLCIMIVTYILTVWSIIRQTNQARQNLYPNKSST------KSRPLTQIKITDDSQSINETTNSADNDVSYSMIGVDDKYCSHSSLSLNSFDSPVKRGS----FKI------SHKNEFTIHLNV---------PTTDMRRSYDFSPKQNLAIKKQSSLTDKNFQS------FNNSFKMSPTRYGNQLSIRKNLSNSFRIHKQSRNSAKRTLAAMNSGKKAVQVLGILFGLFLLCYLPFFVIYLLDFFCIKC--QTMTGPLVSKTEWIGYSASMLNPIVYHIFNPTFRNTFNRLMRCKCYKV 491
BLAST of GCR027 vs. Planmine SMEST
Match: SMESG000032682.1 (SMESG000032682.1) HSP 1 Score: 322.013 bits (824), Expect = 2.528e-101 Identity = 195/513 (38.01%), Postives = 289/513 (56.34%), Query Frame = 2
Query: 158 RYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKRFNYFLVSLAMSDFLCAILVMPISAWKMIDNYYLETINHQWCLIWYSLDVFFTASTIIHLCTISIDRYNALKNPLKIHGQKRYRSLVVQLVCAWIIPFSIACPLFLFALELDK--------------------TREHSSFKGCGPQNAYFILIATIVTFFIPLIIMTVTYVLTVKILYVQRKEAEANLYSNAVASLVFKPKLSSSLAKFTRTPSTKVMSEKKLNGKNENSSAM----HRRSISTSCLVNSLDSEFKETENHNHFEMTPLLAKTTRNNFVENTSMNLCGSDNLKPSLQEDQYKQTLPQRQVSFREQQKTKNHYWKSNTVCTVLENPLALLSHQRSFKMS----------NKTKTDEYSAFYXXXXXXXXXXXXINRSRKAVQTLGILFLLFVICYLPFFVAYLVDFFFKICSVSSTAEKMLTFLEWMGYSGSMFNPIVYHFFNPIFRHTYQRLMKCQCYRVFIRHASSS 1594
RY W ++GL IIP+ ++WGN+LVC+SV++E L+ RFN+FLVSLA+SD LCA+LVMP+SAW M+ N ++ CL WYSLDVFFT++TIIHLC+IS+DRY L NPLK H + SL +++ AW+IPF IACPLF+FAL LD +++ S+KGCGP N YFI+I+T++TF +PL IM VTY+LTV + Q +A NLY N +S +P L + T ++ ++E + N+ S +M + +S +NS DS K F++ + +N F + ++ P+ + P++ ++ ++Q + ++ S SFKMS K ++ + + ++ L +N +KAVQ LGILF LF++CYLPFFV YL+DFF C + +++ EW+GYS SM NPIVYH FNP FR+T+ RLM+C+ + +R+ +S
Sbjct: 29 RYQWPFLGLLIIPLCTIWGNALVCVSVFIEKRLQNRFNFFLVSLAISDLLCALLVMPVSAWNMVRNNNFTSVPRGICLAWYSLDVFFTSTTIIHLCSISLDRYFVLNNPLKYHNTRIRSSLPLKISIAWLIPFCIACPLFIFALRLDHMAGNNRNSVPESGWLSNETISQQLDSYKGCGPHNVYFIIISTVITFVLPLCIMIVTYILTVWSIIRQTNQARQNLYPNK-SSTKSRP-----LTQIKITDDSQSINETTNSADNDVSYSMIGVDDKYCSHSSLSLNSFDSPVKRGS----FKI------SHKNEFTIHLNV---------PTTDMRRSYDFSPKQNLAIKKQSSLTDKNFQ---------------SFNNSFKMSPTRYGNQLSIRKNLSNSFRIHKQSRNSAKRTLAAMNSGKKAVQVLGILFGLFLLCYLPFFVIYLLDFFCIKC--QTMTGPLVSKTEWIGYSASMLNPIVYHIFNPTFRNTFNRLMRCKQIHLCLRNGQAS 499 The following BLAST results are available for this feature:
BLAST of GCR027 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of GCR027 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of GCR027 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of GCR027 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of GCR027 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of GCR027 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of GCR027 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of GCR027 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033206 ID=SMED30033206|Name=GCR027|organism=Schmidtea mediterranea sexual|type=transcript|length=1765bpback to top protein sequence of SMED30033206-orf-1 >SMED30033206-orf-1 ID=SMED30033206-orf-1|Name=SMED30033206-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=497bp MDNGTFPIFNMSFHSRYNWAYVGLFIIPMLSMWGNSLVCISVWVEVGLRKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
