Crooked neck pre-mRNA splicing factor 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033191 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Match: CRNKL1 (crooked neck pre-mRNA splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:15762]) HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0 Identity = 308/648 (47.53%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+++A IY++FV VHPD KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + + +RE+YERAIAN P I++K +W+RYIYLWI YA++EEL + +R +VY L PH+KFTFAK+WI A+ IRQK+L+ AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L +R R IYE A+ + LD P +WKSYIDFE + +E E L+RR+L++ +H +W S+AQ +L L + R+I+EEANK+++ E +R MLL+ W+ FE+++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 180 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGS-------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL 819
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Match: CRNKL1 (crooked neck pre-mRNA splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:15762]) HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0 Identity = 308/648 (47.53%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+++A IY++FV VHPD KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + + +RE+YERAIAN P I++K +W+RYIYLWI YA++EEL + +R +VY L PH+KFTFAK+WI A+ IRQK+L+ AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L +R R IYE A+ + LD P +WKSYIDFE + +E E L+RR+L++ +H +W S+AQ +L L + R+I+EEANK+++ E +R MLL+ W+ FE+++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 168 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGS-------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL 807
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Match: CRNKL1 (crooked neck pre-mRNA splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:15762]) HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0 Identity = 308/648 (47.53%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+++A IY++FV VHPD KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + + +RE+YERAIAN P I++K +W+RYIYLWI YA++EEL + +R +VY L PH+KFTFAK+WI A+ IRQK+L+ AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L +R R IYE A+ + LD P +WKSYIDFE + +E E L+RR+L++ +H +W S+AQ +L L + R+I+EEANK+++ E +R MLL+ W+ FE+++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 19 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGS-------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL 658
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Match: PRPF6 (pre-mRNA processing factor 6 [Source:HGNC Symbol;Acc:HGNC:15860]) HSP 1 Score: 60.077 bits (144), Expect = 1.253e-8 Identity = 85/439 (19.36%), Postives = 166/439 (37.81%), Query Frame = 1 Query: 325 ARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWM------AWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN----WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCG-KNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 AR + RA+ V +WL A +E ++AR + +A +P +W +EE N KI R + E + W + G + A+ + + + +E++ W++ A +N AR++ AL + S + A FE+ E ++ + + A+ + PK +E ++ + + GD + + + Q N + + W + +K +E EN + R + +A ++ P ++ E NI A ++ + L H F K+W+ K +I +++ + AR+ + +C L+ ++E + + R R + K + P W+E EYR + AL+ E +W I EA+ Sbjct: 419 ARIMLSRAVECCPTSVELWLALARLE----TYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKK---SVWLRAAYFEKNHGTRESLEALLQRAVAHCPK--AEVLWLMGAKSKWLAGDVPAARSILALAFQ--------ANPNSEEIWLAAVK-LESENDEYERARRLLAKARSSAP-----------TARVFMKSVKLEWVQDNIRAAQDLCEEALRHYED----FPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQ-ECPNSGILWSEAIFLEAR 823 HSP 2 Score: 60.077 bits (144), Expect = 1.487e-8 Identity = 75/335 (22.39%), Postives = 135/335 (40.30%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A ++ N + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K K E + A+ + AL Y D P ++K + EE++ E+ +E Y L P S ++ E+K G ++T I+ EK +N + W +++ E + + IAN L+ K + AIF E ++++ +C H PH AK++ Sbjct: 542 TWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHY-EDFPKLWMMK--GQIEEQKEMMEKAREAYNQGLKKCPH--STPLWLLLSRLEEKIG-QLTRARAIL-------EKSRLKNPKNPGLWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKC-EHDPHVLLAVAKLF 851
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Match: XAB2 (XPA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14089]) HSP 1 Score: 56.225 bits (134), Expect = 2.113e-7 Identity = 74/347 (21.33%), Postives = 140/347 (40.35%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYG----SDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLS--ENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTC--GNIDRAIEVYSQCL-LHTPHRKFTFAKIW 1275 W+ +A F ++ AR + E+A +++K+V S+W + E+EL+ + A L +A + R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E + + + + SD ++ K A++ R+ E R +++++ ALD P ++ +Y Y + E+++G + YE+ E YD + YIK E + R IY++AI + F ++ C G IDRA +YS C + P F + W Sbjct: 398 WVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAE----YFDGSEPVQN-----RVYKSL-------KVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLE--RARDLFEQALDGCPPKYAKTLYLLYAQLEEEWG--------LARHAMAVYERATRAVEPAQQYDMFNIYIKRAAE-IYGVTHTRGIYQKAI----------EVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTW 707
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Celegans
Match: M03F8.3 (pep chromosome:WBcel235:V:5940024:5943362:1 gene:WBGene00019762.1 transcript:M03F8.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M03F8.3) HSP 1 Score: 530.406 bits (1365), Expect = 1.221e-179 Identity = 291/633 (45.97%), Postives = 428/633 (67.61%), Query Frame = 1 Query: 103 VQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHP-DEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQ--LLDFDTEEEERFPEVLARSREIFEEANKSLKKMESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDD 1986 +QIT+EQLLREAKERELE P P+ KI+ E KEYQ +KR+++E+ IRK+++++ NW+KY +E S EI RAR+VFERA+++ ++ +SIWL+YAEME++CKQ+ HARN+++RA+ I+PRA Q W KY YMEE ++NI AR+IF+RW+ WEPPEQAW ++IN E +Y EI++A ++Y++F+ VH + +NWIK+AKFEE N AR+ A+ ++G ++ +L FA FEERQ+EHER + I+KY LDNLP +E+I++ Y ++EKKFG+++ I++ I+ KR+ YEK++ EN ++YD WF Y++++E E + +++ ++YERAIAN P +K YWRRYIYLWI YA++EEL + DRA +VY C+ PH+ FTFAK+WI A IRQ DL ARK +G AIG+C K+KL+R YI +E L EFDR R LY KF+ P Q WI+FA E L +R R ++ A+ + LD P +WK+YIDFE +E E L+ +L++ H +W S A+ + + +F+ +R+ FE AN+SL+ E +R MLL+ WK+ E G E+++ V +P+ + +R++I EDG+ W E FP D Sbjct: 31 LQITAEQLLREAKERELELIPPAPKTKITDPDELKEYQRKKRKEFEDGIRKNRMQLANWIKYGKWEESIGEIQRARSVFERALDVDHRSISIWLQYAEMEMRCKQINHARNVFDRAITIMPRAMQFWLKYSYMEEVIENIPGARQIFERWIEWEPPEQAWQTYINFELRYKEIDRARSVYQRFLHVHGINVQNWIKYAKFEERNGYIGNARAAYEKAMEYFGEEDINETVLVAFALFEERQKEHERARGIFKYGLDNLPSNRTEEIFKHYTQHEKKFGERVGIEDVIISKRKTQYEKMVEENGYNYDAWFDYLRLLENEETDREEVEDVYERAIANIPPHSEKRYWRRYIYLWINYALYEELVAKDFDRARQVYKACIDIIPHKTFTFAKVWIMFAHFEIRQLDLNAARKIMGVAIGKCPKDKLFRAYIDLELQLREFDRCRKLYEKFLESSPESSQTWIKFAELETLLGDTDRSRAVFTIAVQQPALDMPELLWKAYIDFEIACEEHEKARDLYETLLQRTNHIKVWISMAEFEQTIGNFEG------------ARKAFERANQSLENAEKEERLMLLEAWKECETKSGDQEALKRVETMMPRRVKKRRQIQTEDGVDAGWEEYFDYIFPQD 651
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Celegans
Match: M03F8.3 (pep chromosome:WBcel235:V:5940024:5943362:1 gene:WBGene00019762.1 transcript:M03F8.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M03F8.3) HSP 1 Score: 526.939 bits (1356), Expect = 2.729e-178 Identity = 291/634 (45.90%), Postives = 427/634 (67.35%), Query Frame = 1 Query: 103 VQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHP-DEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKP---LIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKMESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDD 1986 +QIT+EQLLREAKERELE P P+ KI+ E KEYQ +KR+++E+ IRK+++++ NW+KY +E S EI RAR+VFERA+++ ++ +SIWL+YAEME++CKQ+ HARN+++RA+ I+PRA Q W KY YMEE ++NI AR+IF+RW+ WEPPEQAW ++IN E +Y EI++A ++Y++F+ VH + +NWIK+AKFEE N AR+ A+ ++G ++ +L FA FEERQ+EHER + I+KY LDNLP +E+I++ Y ++EKKFG+++ I++ I+ KR+ YEK++ EN ++YD WF Y++++E E + +++ ++YERAIAN P ++K YWRRYIYLWI YA++EEL + DRA +VY C+ PH+ FTFAK+WI A IRQ DL ARK +G AIG+C K+KL+R YI +E L EFDR R LY KF+ P Q WI+FA E L +R R ++ A+ + LD P +WK+YIDFE +E E L+ +L++ H +W S A+ + + E +R+ FE AN+SL+ E +R MLL+ WK+ E G E+++ V +P+ + +R++I EDG+ W E FP D Sbjct: 31 LQITAEQLLREAKERELELIPPAPKTKITDPDELKEYQRKKRKEFEDGIRKNRMQLANWIKYGKWEESIGEIQRARSVFERALDVDHRSISIWLQYAEMEMRCKQINHARNVFDRAITIMPRAMQFWLKYSYMEEVIENIPGARQIFERWIEWEPPEQAWQTYINFELRYKEIDRARSVYQRFLHVHGINVQNWIKYAKFEERNGYIGNARAAYEKAMEYFGEEDINETVLVAFALFEERQKEHERARGIFKYGLDNLPSNRTEEIFKHYTQHEKKFGERVGIEDVIISKRKTQYEKMVEENGYNYDAWFDYLRLLENEETDREEVEDVYERAIANIPPHSYFQEKRYWRRYIYLWINYALYEELVAKDFDRARQVYKACIDIIPHKTFTFAKVWIMFAHFEIRQLDLNAARKIMGVAIGKCPKDKLFRAYIDLELQLREFDRCRKLYEKFLESSPESSQTWIKFAELETLLGDTDRSRAVFTIAVQQPALDMPELLWKAYIDFEIACEEHEKARDLYETLLQRTNHIKVWISMAEFEQTIGNFE----------GARKAFERANQSLENAEKEERLMLLEAWKECETKSGDQEALKRVETMMPRRVKKRRQIQTEDGVDAGWEEYFDYIFPQD 654
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Celegans
Match: syf-1 (SYF pre-mRNA splicing factor homolog [Source:UniProtKB/TrEMBL;Acc:P91175]) HSP 1 Score: 53.5286 bits (127), Expect = 4.606e-7 Identity = 80/363 (22.04%), Postives = 140/363 (38.57%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEVS----IWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWI-KWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLS--ENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ A ++ AR FE A+ + VS +W YAEME++ K+ + A + +RA C++P+ +N+ S + R W + + E+ G +E +Y K +++ I +A F E N +A + + KF +R ++ ER +++++ L+N P ++ I+ Y + E++ G + Y + S + + + YIK + +E I R I+ERAI+ P E K Y + E T G IDRA +Y+ + P F W + + AT R L Sbjct: 404 WIGLAKLYEDNGDLDAARKTFETAVISQFGGVSELANVWCAYAEMEMKHKRAKAALTVMQRA-CVVPKPGD-----------YENMQSVQARVHR------SPILWAMYADYEECCGTVESCRKVYDKMIELRVASPQMIMNYAMFLEENEYFELAFQAYEKGIALFKWPGVFDIWNTYLVKFIKRYGGKKLERARDLFEQCLENCPPTHAKYIFLLYAKLEEEHG--------LARHALSIYNRACSGVDRADMHSMYNIYIKKV-QEMYGIAQCRPIFERAISELP--EDKSRAMSLRYAQL------ETTVGEIDRARAIYAHAAEISDPKVHVKFWDTW---KNFEVAHGNEATVRDML 728
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Fly
Match: crn (gene:FBgn0000377 transcript:FBtr0070418) HSP 1 Score: 522.702 bits (1345), Expect = 3.653e-177 Identity = 294/650 (45.23%), Postives = 443/650 (68.15%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYA--QLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKER+LE P PP+QKIS E +YQ +KR+ +E+N+RK+++ + +W+KYA +E Q EI RAR+++ERA++ ++ V++WLKYAEME++ KQV HARNL++RA+ I+PR NQ WYKY YMEE L+N+ AR++F+RWM W+P EQAW +++N E +Y EI++A IY++FV VHPD KNWIK+A+FEE++ +R V A+ F+G D + FA+FEE Q+EH+R + IYKYALD+LPK ++++++AY ++EKK+GD+ I++ IV KR++ YE+ ++ N +YD WF Y++++E E D IRE YERAI+N P +K +WRRYIYLWI YA++EEL + +R ++Y CL PH++FTF+K+W+ A+ IR K+L ARK LG AIG C ++KL+R YI +E L EF+R R LY KF+ F P W++FA E L +R R I+E A+ + LD P +WK+YIDFE + E E +L+ R+LE+ +H +W S+A ++ L D+ + LAR I+E AN+ L+++ + R +LL+ W+ FE D + ++ V +K+P+ I +R++I +++G+ W E FP+D N+ ++ Sbjct: 14 KNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFGDDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAANPTNYDAWFDYLRLIEAEGDR-DQIRETYERAISNVPPANEKNFWRRYIYLWINYALYEELEAEDAERTRQIYKTCLELIPHKQFTFSKLWLLYAQFEIRCKELQRARKALGLAIGMCPRDKLFRGYIDLEIQLREFERCRMLYEKFLEFGPENCVTWMKFAELENLLGDTDRARAIFELAVQQPRLDMPELLWKAYIDFEVALGETELARQLYERLLERTQHVKVWMSFAKFEMGLSHGDSGPDAELNVQLARR--IYERANEMLRQLGDKESRVLLLEAWRDFERDASDSQEMQKVMDKMPRRIKKRQKIVSDNGVEEGWEEVFDYIFPEDEMARPNLKLL 660
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Fly
Match: CG6841 (gene:FBgn0036828 transcript:FBtr0346816) HSP 1 Score: 54.299 bits (129), Expect = 3.813e-7 Identity = 54/218 (24.77%), Postives = 87/218 (39.91%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEK 924 W+ A F +N AR V+ A+ I + SIWL+ A E + L +RA+ P++ LW + ++ +AR I P E W + + LE + E E+A + K P + +K A+ E + A +L A+ + D P ++K + EE+QR + Y L P + I A E K Sbjct: 532 TWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVEVF-PDFPKLWMMK--GQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERK 746
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Fly
Match: CG6841 (gene:FBgn0036828 transcript:FBtr0075068) HSP 1 Score: 54.299 bits (129), Expect = 3.813e-7 Identity = 54/218 (24.77%), Postives = 87/218 (39.91%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEK 924 W+ A F +N AR V+ A+ I + SIWL+ A E + L +RA+ P++ LW + ++ +AR I P E W + + LE + E E+A + K P + +K A+ E + A +L A+ + D P ++K + EE+QR + Y L P + I A E K Sbjct: 532 TWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVEVF-PDFPKLWMMK--GQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERK 746
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Fly
Match: fand (gene:FBgn0033859 transcript:FBtr0087623) HSP 1 Score: 51.2174 bits (121), Expect = 3.375e-6 Identity = 71/322 (22.05%), Postives = 132/322 (40.99%), Query Frame = 1 Query: 172 PQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCI-----------------LPRANQLWYKYVYMEEKLKNIDSARKIFKRWM-------------------------------------AWEPPEQAWHSFIN--LEKKYG-EIEKAHAIYKKFVQVHPDEKN---WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQRE---HERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGD 936 P + IST TE + +Q +Q KL + W+++A F + ++ AR VFER + Y +V ++W ++AEMEL+ +Q + A L +RA + L R+ ++W Y +EE + + +++R + W W+S++ LE+ G ++E+A ++++ + P E ++ +AK EE + A SV A D + + F ++ E R +EIY+ A+++LP+ + + E E K G+ Sbjct: 370 PAEIISTYTEAVQ-TVQPKQAV------GKLHTL-WVEFAKFYEANGQVEDARVVFERGTEVEYVKVEDLAAVWCEWAEMELRQQQFEAALKLMQRATAMPKRKIAYYDDTETVQARLHRSLKVWSMYADLEESFGTFKTCKAVYERIIDLKICTPQIIINYGMFLEEHNYFEEAYRAYEKGISLFKWPNVYDIWNSYLTKFLERYGGTKLERARDLFEQCLDQCPPEHAKYFYLLYAKLEEEHGLARHAMSVYDRATSAVKEDE----MFDMYNIFIKKAAEIYGLPRTREIYEKAIESLPEQNMRHMCVKFAELETKLGE 679
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:ZFIN;Acc:ZDB-GENE-040426-694]) HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0 Identity = 306/648 (47.22%), Postives = 449/648 (69.29%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ + E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S E+ R+R+++ERA+++ ++ +++WLKYAEME++ +QV HARN+++RA+ ILPR NQ WYKY YMEE L NI R++F+RWM WEP EQAWHS+IN E +Y E++KA +IY+ FV VHP+ KNWIK+A FEE + + R V A+ F+G + ++ FA+FEE+Q+E ERV+ IYKYALD +PK ++++++ Y +EK+FGD+ I++ IV KR+ YE+ + N H+YD WF Y++++ E + + D +RE+YERAIAN P I++K +WRRYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ + IRQK+L AR+ LG AIG+C KNKL++ YI++E L EFDR R LY K++ F P WI+FA E L +R R I+E A+ + LD P +WKSYIDFE + +E++N L++R+L++ +H +W SYAQ + L DTE+ + R R+++EEANK ++ E +R MLL+ W+ +E+++G+ E V LP+ + +R++I EDG W E FP+D N+ ++ Sbjct: 18 KNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDKEELNDYKLKKRKGFEDNIRKNRTVISNWIKYAQWEESLQEVQRSRSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNIAGCRQVFERWMEWEPEEQAWHSYINFELRYKEVDKARSIYENFVMVHPEVKNWIKYAHFEEKHGYVARGRKVFERAVEFFGEEQVSENLYVAFARFEEKQKEFERVRVIYKYALDRIPKQQAQELFKNYTVFEKRFGDRRGIEDVIVSKRRFQYEEEVKANPHNYDAWFDYLRLV-ESDADADTVREVYERAIANIPPIQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYKACLELIPHKKFTFAKIWLLYGQFEIRQKNLQNARRGLGTAIGKCPKNKLFKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDTDRSRAIFELAIGQPRLDMPEVLWKSYIDFEIEQEEYDNTRGLYKRLLQRTQHVKVWISYAQFE-LSIDTEDR------VQRCRQVYEEANKGMQNCEEKEERLMLLESWRDYEEEFGSFTHKERVRKLLPEKVKKRRKITAEDGSDAGWEEYYDYIFPEDAANQPNLKLL 657
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Match: xab2 (XPA binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-040426-685]) HSP 1 Score: 63.5438 bits (153), Expect = 6.358e-10 Identity = 84/361 (23.27%), Postives = 149/361 (41.27%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F +I AR +FE+A ++YK+V ++W +Y EMEL+ + A + +A I R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E +N + + + N KF +R ++ ER +++++ ALD P ++ IY Y + E+++G + V +R V +E H + F+ E + R IY++AI P + R+ + E G IDRA +YS C + P F + W E IR + T R+ L Sbjct: 393 WVSFAKFYEDNEQIDDARTIFEKATKVNYKQVDDLAAVWCEYGEMELRHENYDQALRILRKATAIPARKAE----YFDSSEPVQN-----RVYKSL-------KVWSMLADLEESLGTFQSTKAVYDRIIDLRIATPQIIINYAMFLEEHNYFEESFKAYERGIALFKWPNVHDIWNTYLTKFIDRYGGKKLERARDLFEQALDGCPAKYAKTIYLLYAKLEEEYG--LARHAMAVYERAT--AAVEAEERH---QMFNIYIKRAAEIYGVTHTRAIYQKAIEVLPDEHARDMCLRFADM--------ESKLGEIDRARAIYSYCSQICDPRVTAHFWQTW---KEFEIRHGNEDTIREML 719
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Match: prpf6 (PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-030131-2575]) HSP 1 Score: 61.2326 bits (147), Expect = 3.482e-9 Identity = 73/335 (21.79%), Postives = 133/335 (39.70%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A +S + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K + E A + T AL Y D P +++ + EE+ +R +E Y L P +S ++ E+K G ++T I+ EK +N + W +++ E + + IAN L+ K + A+F E ++++ +C H PH AK++ Sbjct: 545 TWMEDADSCVSHGALECARAIYAHALQVFPSKKSVWLRAAYFEKNNGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVRLEWVLGNIEAAHELCTEALKHY-EDFPKLWMMR--GQIEEQSESIDRAREAYNQGLKKCPHSMS--LWLLLSRLEEKVG-QLTRARAIL-------EKARLKNPQSPELWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 854
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Match: prpf6 (PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-030131-2575]) HSP 1 Score: 61.2326 bits (147), Expect = 3.610e-9 Identity = 73/335 (21.79%), Postives = 133/335 (39.70%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A +S + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K + E A + T AL Y D P +++ + EE+ +R +E Y L P +S ++ E+K G ++T I+ EK +N + W +++ E + + IAN L+ K + A+F E ++++ +C H PH AK++ Sbjct: 575 TWMEDADSCVSHGALECARAIYAHALQVFPSKKSVWLRAAYFEKNNGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVRLEWVLGNIEAAHELCTEALKHY-EDFPKLWMMR--GQIEEQSESIDRAREAYNQGLKKCPHSMS--LWLLLSRLEEKVG-QLTRARAIL-------EKARLKNPQSPELWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 884
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 58.9214 bits (141), Expect = 2.261e-8 Identity = 58/261 (22.22%), Postives = 116/261 (44.44%), Query Frame = 1 Query: 337 FERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERAL-CILPRANQ----LWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQ-VHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAI 1101 FER + +WL+Y LQ Q++ AR + ERAL I R Q +W + +E DS +K+F+R + + P + ++ K +I++A ++YK V+ D+ ++ + F ++ A ++L AL S ++ FA+ E + E+ K ++ L PK D++ + + K G + ++E + R H + + + + Y E++N + I+ + ++A+ Sbjct: 1553 FERLLLSSPDSSLLWLQYMAFHLQATQIEQARAVAERALKTISFREEQEKLNIWVAMLNLENMYGTPDSLQKVFERAIQYCEPLLVYQQLADIYAKSEKIKEAESLYKSMVKRFRQDKAVYLSYGTFLLRQRQSDAANALLQRALQSLSSKE-HVDLIARFARLEFQFGNSEKAKSMFDKVLTTYPK--RTDLWSVFIDLMVKHGSQKEVRE--LFDRVIHLSVSVKKIKFFFKRYLEY----EKKNGTPETIQVVKQKAL 1804
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Match: serpinb1 (serpin family B member 1 [Source:Xenbase;Acc:XB-GENE-1217264]) HSP 1 Score: 568.155 bits (1463), Expect = 0.000e+0 Identity = 307/648 (47.38%), Postives = 450/648 (69.44%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ R++F+RWM W+P EQAWHS+IN E +Y E+++A +IY++FV VHPD KNWIK+A+FEE + + AR V ++ F+G D+ ++ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKK+GD+ I++ IV KR+ YE+ + N H+YD WF Y++++ E + + D +RE+YERAIAN P ++K +W+RYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ ++ +RQK+L AR+ LG +IG+ KNKL++ YI++E L EFDR R LY KF+ F P WI+F+ E L ER R IYE A+ + LD P +WKSYIDFE + +EFE L+RR+L++ +H +W S+AQ +L + + L + R+I+EEANKSL+ E +R MLL+ W+ FE+++GT+ + E VA +P+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 18 KNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKSRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGTRQVFERWMEWQPEEQAWHSYINFELRYKEVDRARSIYERFVIVHPDVKNWIKYARFEEKHGYIAHARKVYERSVEFFGEDHMDENLYVSFAKFEEHQKEFERVRVIYKYALDRISKQQAQELFKNYTIFEKKYGDRRGIEDIIVNKRRFQYEEEVKANPHNYDAWFDYLRLV-ESDADPDTVREVYERAIANVPPTKEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQACLELIPHKKFTFAKIWLMYSQFEVRQKNLPFARRALGTSIGKSPKNKLFKGYIELELQLREFDRCRKLYEKFLEFAPENCTTWIKFSELETILGDAERARAIYELAIGQPRLDMPEVLWKSYIDFEIEQEEFEKTRTLYRRLLQRTQHVKVWISFAQFELTSSNE-------DTLGKCRQIYEEANKSLRNCEEKEERLMLLESWRNFEEEFGTESTKERVAKLMPEKVKKRRKLQGEDGSDAGWEEYYDYIFPEDAANQPNLKLL 657
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Match: serpinb1 (serpin family B member 1 [Source:Xenbase;Acc:XB-GENE-1217264]) HSP 1 Score: 549.28 bits (1414), Expect = 0.000e+0 Identity = 300/648 (46.30%), Postives = 445/648 (68.67%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ R++F+RWM W+P EQAWHS+IN E +Y E+++A +IY++++ NWIK+A+FEE + + AR V ++ F+G D+ ++ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKK+GD+ I++ IV KR+ YE+ + N H+YD WF Y++++ E + + D +RE+YERAIAN P ++K +W+RYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ ++ +RQK+L AR+ LG +IG+ KNKL++ YI++E L EFDR R LY KF+ F P WI+F+ E L ER R IYE A+ + LD P +WKSYIDFE + +EFE L+RR+L++ +H +W S+AQ +L + + L + R+I+EEANKSL+ E +R MLL+ W+ FE+++GT+ + E VA +P+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 7 KNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKSRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGTRQVFERWMEWQPEEQAWHSYINFELRYKEVDRARSIYERYILC-----NWIKYARFEEKHGYIAHARKVYERSVEFFGEDHMDENLYVSFAKFEEHQKEFERVRVIYKYALDRISKQQAQELFKNYTIFEKKYGDRRGIEDIIVNKRRFQYEEEVKANPHNYDAWFDYLRLV-ESDADPDTVREVYERAIANVPPTKEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQACLELIPHKKFTFAKIWLMYSQFEVRQKNLPFARRALGTSIGKSPKNKLFKGYIELELQLREFDRCRKLYEKFLEFAPENCTTWIKFSELETILGDAERARAIYELAIGQPRLDMPEVLWKSYIDFEIEQEEFEKTRTLYRRLLQRTQHVKVWISFAQFELTSSNE-------DTLGKCRQIYEEANKSLRNCEEKEERLMLLESWRNFEEEFGTESTKERVAKLMPEKVKKRRKLQGEDGSDAGWEEYYDYIFPEDAANQPNLKLL 641
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Match: serpinb1 (serpin family B member 1 [Source:Xenbase;Acc:XB-GENE-1217264]) HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0 Identity = 300/648 (46.30%), Postives = 445/648 (68.67%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ R++F+RWM W+P EQAWHS+IN E +Y E+++A +IY++++ NWIK+A+FEE + + AR V ++ F+G D+ ++ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKK+GD+ I++ IV KR+ YE+ + N H+YD WF Y++++ E + + D +RE+YERAIAN P ++K +W+RYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ ++ +RQK+L AR+ LG +IG+ KNKL++ YI++E L EFDR R LY KF+ F P WI+F+ E L ER R IYE A+ + LD P +WKSYIDFE + +EFE L+RR+L++ +H +W S+AQ +L + + L + R+I+EEANKSL+ E +R MLL+ W+ FE+++GT+ + E VA +P+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 8 KNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKSRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGTRQVFERWMEWQPEEQAWHSYINFELRYKEVDRARSIYERYILC-----NWIKYARFEEKHGYIAHARKVYERSVEFFGEDHMDENLYVSFAKFEEHQKEFERVRVIYKYALDRISKQQAQELFKNYTIFEKKYGDRRGIEDIIVNKRRFQYEEEVKANPHNYDAWFDYLRLV-ESDADPDTVREVYERAIANVPPTKEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQACLELIPHKKFTFAKIWLMYSQFEVRQKNLPFARRALGTSIGKSPKNKLFKGYIELELQLREFDRCRKLYEKFLEFAPENCTTWIKFSELETILGDAERARAIYELAIGQPRLDMPEVLWKSYIDFEIEQEEFEKTRTLYRRLLQRTQHVKVWISFAQFELTSSNE-------DTLGKCRQIYEEANKSLRNCEEKEERLMLLESWRNFEEEFGTESTKERVAKLMPEKVKKRRKLQGEDGSDAGWEEYYDYIFPEDAANQPNLKLL 642
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Match: adgrb1 (adhesion G protein-coupled receptor B1 [Source:Xenbase;Acc:XB-GENE-985157]) HSP 1 Score: 65.4698 bits (158), Expect = 2.456e-10 Identity = 81/364 (22.25%), Postives = 150/364 (41.21%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLS--ENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTC--GNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F +I AR + +RA + Y V S+W ++ EMEL+ + + A N+ +A + R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E +N + + + N +KF R ++ ER +++++ +LD P+ +++I+ Y + E++ G + YE+ E Y+ + YIK E + R IYERAI + L +++ F ++ C G IDRA +YS C R F + W + +R + T R+ L Sbjct: 380 WVAFAKFYEDNGQIEDARAILQRATLVQYTHVDELASVWCQFGEMELRHENYEQALNILRKATAVPARKAE----YFDSSEPVQN-----RLYKSL-------RVWSMLADLEESLGTFKSTKAVYDRIIDLRIATPQIIINYALFLEEHNYFEESFKAYERGIALFRWPNVYDIWSTYLSKFIARYGGKKLERARDLFEQSLDGCPRKFAKNIFLLYAKLEEEHG--------LARHAMALYERATQAVETGEQYEMFNIYIKRA-AEIYGVTHTRSIYERAI--ELLTDEQSREMCLR--------FADMECKLGEIDRARAIYSYCSQMCDPRVTGFWQTW---RDFEVRHGNEDTLREML 705
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Match: adgrb1 (adhesion G protein-coupled receptor B1 [Source:Xenbase;Acc:XB-GENE-985157]) HSP 1 Score: 64.3142 bits (155), Expect = 5.097e-10 Identity = 81/365 (22.19%), Postives = 151/365 (41.37%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLS--ENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTC--GNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F +I AR + +RA + Y V S+W ++ EMEL+ + + A N+ +A + R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E +N + + + N +KF R ++ ER +++++ +LD P+ +++I+ Y + E++ G + YE+ E Y+ + YIK E + R IYERAI + L +++ F ++ C G IDRA +YS C + P F + W + +R + T R+ L Sbjct: 367 WVAFAKFYEDNGQIEDARAILQRATLVQYTHVDELASVWCQFGEMELRHENYEQALNILRKATAVPARKAE----YFDSSEPVQN-----RLYKSL-------RVWSMLADLEESLGTFKSTKAVYDRIIDLRIATPQIIINYALFLEEHNYFEESFKAYERGIALFRWPNVYDIWSTYLSKFIARYGGKKLERARDLFEQSLDGCPRKFAKNIFLLYAKLEEEHG--------LARHAMALYERATQAVETGEQYEMFNIYIKRAAE-IYGVTHTRSIYERAI--ELLTDEQSREMCLR--------FADMECKLGEIDRARAIYSYCSQMCDPRLTAGFWQTW---RDFEVRHGNEDTLREML 693
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Match: Crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:MGI Symbol;Acc:MGI:1914127]) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 309/648 (47.69%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+E+A IY++FV VHP KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + D +RE+YERAIAN P I++K +W+RYIYLW+ YA++EEL + +R +VY L PH+KFTFAK+W+Y A+ IRQK+L AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L ER R IYE A+ + LD P +WKSYIDFE + +E E L+R++L++ +H +W S+AQ +L +A+ R+I+EEANK+++ E +R MLL+ W+ FED++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 19 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-ADTVREVYERAIANVPPIQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQHVKVWISFAQFELSSGKEGS-------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAANQPNLKLL 658
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Match: Prpf6 (pre-mRNA splicing factor 6 [Source:MGI Symbol;Acc:MGI:1922946]) HSP 1 Score: 65.4698 bits (158), Expect = 2.098e-10 Identity = 86/439 (19.59%), Postives = 166/439 (37.81%), Query Frame = 1 Query: 325 ARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWM------AWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN----WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCG-KNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 AR + RA+ V +WL A +E ++AR + +A +P +W +EE N KI R + E + W + G + A+ + + + +E++ W++ A +N AR++ AL + S + A FE+ E ++ + + A+ + PK +E ++ + + GD + + + Q N + + W + +K +E EN + R + +A ++ P ++ E GNI A E+ + L H F K+W+ K +I + + + AR+ + +C L+ ++E + + R R + K + P W+E EYR + AL+ E +W + EA+ Sbjct: 419 ARIMLSRAVECCPTSVELWLALARLE----TYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKK---SVWLRAAYFEKNHGTRESLEALLQRAVAHCPK--AEVLWLMGAKSKWLAGDVPAARSILALAFQ--------ANPNSEEIWLAAVK-LESENNEYERARRLLAKARSSAP-----------TARVFMKSVKLEWVLGNISAAQELCEEALRHYED----FPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQ-ECPNSGILWSEAVFLEAR 823 HSP 2 Score: 59.6918 bits (143), Expect = 1.286e-8 Identity = 75/335 (22.39%), Postives = 134/335 (40.00%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A ++ N + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K K E S A+ + AL Y D P ++K + EE+ E+ +E Y L P S ++ E+K G ++T I+ EK +N + W +++ E + + IAN L+ K + A+F E ++++ +C H PH AK++ Sbjct: 542 TWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALRHY-EDFPKLWMMK--GQIEEQGELMEKAREAYNQGLKKCPH--STPLWLLLSRLEEKIG-QLTRARAIL-------EKSRLKNPKNPGLWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 851
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Match: Prpf6 (pre-mRNA splicing factor 6 [Source:MGI Symbol;Acc:MGI:1922946]) HSP 1 Score: 65.4698 bits (158), Expect = 2.098e-10 Identity = 86/439 (19.59%), Postives = 166/439 (37.81%), Query Frame = 1 Query: 325 ARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWM------AWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN----WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCG-KNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 AR + RA+ V +WL A +E ++AR + +A +P +W +EE N KI R + E + W + G + A+ + + + +E++ W++ A +N AR++ AL + S + A FE+ E ++ + + A+ + PK +E ++ + + GD + + + Q N + + W + +K +E EN + R + +A ++ P ++ E GNI A E+ + L H F K+W+ K +I + + + AR+ + +C L+ ++E + + R R + K + P W+E EYR + AL+ E +W + EA+ Sbjct: 419 ARIMLSRAVECCPTSVELWLALARLE----TYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKK---SVWLRAAYFEKNHGTRESLEALLQRAVAHCPK--AEVLWLMGAKSKWLAGDVPAARSILALAFQ--------ANPNSEEIWLAAVK-LESENNEYERARRLLAKARSSAP-----------TARVFMKSVKLEWVLGNISAAQELCEEALRHYED----FPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQ-ECPNSGILWSEAVFLEAR 823 HSP 2 Score: 59.6918 bits (143), Expect = 1.286e-8 Identity = 75/335 (22.39%), Postives = 134/335 (40.00%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A ++ N + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K K E S A+ + AL Y D P ++K + EE+ E+ +E Y L P S ++ E+K G ++T I+ EK +N + W +++ E + + IAN L+ K + A+F E ++++ +C H PH AK++ Sbjct: 542 TWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALRHY-EDFPKLWMMK--GQIEEQGELMEKAREAYNQGLKKCPH--STPLWLLLSRLEEKIG-QLTRARAIL-------EKSRLKNPKNPGLWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 851
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Match: Xab2 (XPA binding protein 2 [Source:MGI Symbol;Acc:MGI:1914689]) HSP 1 Score: 55.8398 bits (133), Expect = 1.649e-7 Identity = 78/363 (21.49%), Postives = 143/363 (39.39%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTC--GNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F ++ AR + E+A +++K+V S+W + E+EL+ + A L +A + R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E + + + + N KF R R+ ER +++++ ALD P ++ +Y Y + E+++G + V R E YD + YIK E + R IY++AI + F ++ C G IDRA +YS C + P F + W + +R + T R+ L Sbjct: 398 WVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAE----YFDGSEPVQN-----RVYKSL-------KVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISRYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWG--LARHAMAVYDRATR----AVEPAQQYDMFNIYIKRAAE-IYGVTHTRGIYQKAI----------EVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTW---KDFEVRHGNEDTIREML 724
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Match: Pdcd11 (programmed cell death 11 [Source:MGI Symbol;Acc:MGI:1341788]) HSP 1 Score: 54.299 bits (129), Expect = 5.993e-7 Identity = 38/164 (23.17%), Postives = 85/164 (51.83%), Query Frame = 1 Query: 184 ISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAIN-IHYKE-VSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKR--WMAWEPPEQA--WHSFINLEKKYGEIEKAHAIYKKFVQ 657 I T++EK + + + Y +++ + + W+KY +F + +++ + V +RA+ + KE V + +K+A++E Q V+ A+ ++E L P+ +W Y+ M K + + R IF+R ++ P + +++ EK++G + A+ K ++ Sbjct: 1691 IYTKSEKYK---EAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALE 1851
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Match: sp|P63155|CRNL1_RAT (Crooked neck-like protein 1 OS=Rattus norvegicus OX=10116 GN=Crnkl1 PE=2 SV=1) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 309/648 (47.69%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+E+A IY++FV VHP KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + D +RE+YERAIAN P I++K +W+RYIYLW+ YA++EEL + +R +VY L PH+KFTFAK+W+Y A+ IRQK+L AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L ER R IYE A+ + LD P +WKSYIDFE + +E E L+R++L++ +H +W S+AQ +L +A+ R+I+EEANK+++ E +R MLL+ W+ FED++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 19 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-ADTVREVYERAIANVPPIQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQHVKVWISFAQFELSSGKEGS-------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAANQPNLKLL 658
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Match: sp|P63154|CRNL1_MOUSE (Crooked neck-like protein 1 OS=Mus musculus OX=10090 GN=Crnkl1 PE=1 SV=1) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 309/648 (47.69%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+E+A IY++FV VHP KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + D +RE+YERAIAN P I++K +W+RYIYLW+ YA++EEL + +R +VY L PH+KFTFAK+W+Y A+ IRQK+L AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L ER R IYE A+ + LD P +WKSYIDFE + +E E L+R++L++ +H +W S+AQ +L +A+ R+I+EEANK+++ E +R MLL+ W+ FED++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 19 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-ADTVREVYERAIANVPPIQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQHVKVWISFAQFELSSGKEGS-------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAANQPNLKLL 658
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Match: sp|Q9BZJ0|CRNL1_HUMAN (Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4) HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0 Identity = 308/648 (47.53%), Postives = 447/648 (68.98%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PPQQKI+ E E +Y+L+KR+ +E+NIRK++ I NW+KYA +E S EI RAR+++ERA+++ Y+ +++WLKYAEME++ +QV HARN+++RA+ LPR NQ WYKY YMEE L N+ AR++F+RWM W+P EQAWHS+IN E +Y E+++A IY++FV VHPD KNWIK+A+FEE + + AR V A+ F+G ++ H+ FAKFEE Q+E ERV+ IYKYALD + K ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + + +RE+YERAIAN P I++K +W+RYIYLWI YA++EEL + +R +VY L PH+KFTFAK+WI A+ IRQK+L+ AR+ LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P +WI+FA E L +R R IYE A+ + LD P +WKSYIDFE + +E E L+RR+L++ +H +W S+AQ +L L + R+I+EEANK+++ E +R MLL+ W+ FE+++GT E V +P+ + +R+++ +DG W E FP+D N+ ++ Sbjct: 180 KNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAE-AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGS-------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL 819
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Match: sp|P17886|CRN_DROME (Protein crooked neck OS=Drosophila melanogaster OX=7227 GN=crn PE=2 SV=2) HSP 1 Score: 522.702 bits (1345), Expect = 3.662e-176 Identity = 294/650 (45.23%), Postives = 443/650 (68.15%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYA--QLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKER+LE P PP+QKIS E +YQ +KR+ +E+N+RK+++ + +W+KYA +E Q EI RAR+++ERA++ ++ V++WLKYAEME++ KQV HARNL++RA+ I+PR NQ WYKY YMEE L+N+ AR++F+RWM W+P EQAW +++N E +Y EI++A IY++FV VHPD KNWIK+A+FEE++ +R V A+ F+G D + FA+FEE Q+EH+R + IYKYALD+LPK ++++++AY ++EKK+GD+ I++ IV KR++ YE+ ++ N +YD WF Y++++E E D IRE YERAI+N P +K +WRRYIYLWI YA++EEL + +R ++Y CL PH++FTF+K+W+ A+ IR K+L ARK LG AIG C ++KL+R YI +E L EF+R R LY KF+ F P W++FA E L +R R I+E A+ + LD P +WK+YIDFE + E E +L+ R+LE+ +H +W S+A ++ L D+ + LAR I+E AN+ L+++ + R +LL+ W+ FE D + ++ V +K+P+ I +R++I +++G+ W E FP+D N+ ++ Sbjct: 14 KNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFGDDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAANPTNYDAWFDYLRLIEAEGDR-DQIRETYERAISNVPPANEKNFWRRYIYLWINYALYEELEAEDAERTRQIYKTCLELIPHKQFTFSKLWLLYAQFEIRCKELQRARKALGLAIGMCPRDKLFRGYIDLEIQLREFERCRMLYEKFLEFGPENCVTWMKFAELENLLGDTDRARAIFELAVQQPRLDMPELLWKAYIDFEVALGETELARQLYERLLERTQHVKVWMSFAKFEMGLSHGDSGPDAELNVQLARR--IYERANEMLRQLGDKESRVLLLEAWRDFERDASDSQEMQKVMDKMPRRIKKRQKIVSDNGVEEGWEEVFDYIFPEDEMARPNLKLL 660
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Match: sp|Q5BDX1|CLF1_EMENI (Pre-mRNA-splicing factor clf1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=clf1 PE=3 SV=2) HSP 1 Score: 503.827 bits (1296), Expect = 4.408e-169 Identity = 279/663 (42.08%), Postives = 427/663 (64.40%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERF------PEVLARSREIFEEANKSLKKME-SSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVIDDFLKNVQNW 2046 +NK PAPVQI S + L E + + P Q+ + E EYQ +KR+++E+ +R++++ + NWM+YA++E+ Q E RAR++FERA+++ V +W++Y E E++ + + HARNL +RA+ ILPR ++LWYKYVYMEE L NI R++F+RWM+WEP E AW ++I LEK+Y E E+A AI+++F VHP+ +NWIKWA+FEE + + R V A+ G D + +A+FE + +E+ER + IYKYALD LP+ S +++AY +EK+FGD+ ++ I+ KR+ YE+ L EN +YD WF + + +EE++ + + +R++YERAIA P ++K +WRRYIYLWI YA++EE+ +IDRA +VY++CL PH+KFTFAK+W+ KA+ +RQ +L ARKTLG AIG C K+KL+R YI +E L EF R RTLY K I + P+ Q+WI++A E L ER R IYE + + LD P VWK+YIDFE E+E +L+ R+L++ +H +W +YA+ ++ D EEEE E R+R +FE A++ K+ E +R LL W+ FE +G+ E I+ + ++P+ + +R+++D++ + E FP D Q N+S + L+ W Sbjct: 11 KNKAPAPVQI-SAEQLLREAVDRQEPSLQAPTQRFADLEELHEYQGRKRKEFEDYVRRNRINMNNWMRYAAWELEQKEFRRARSIFERALDVDSTSVPLWIRYIESEMRNRNINHARNLLDRAVTILPRVDKLWYKYVYMEETLGNIPGTRQVFERWMSWEPDEGAWSAYIKLEKRYNEFERARAIFQRFTIVHPEPRNWIKWARFEEEYGTSDLVREVYGLAVETLGEDFMDEKLFIAYARFETKLKEYERARAIYKYALDRLPRSKSITLHKAYTTFEKQFGDREGVENVILAKRRVQYEEQLKENLRNYDVWFDFAR-LEEQSGDPERVRDVYERAIAQIPPSQEKRHWRRYIYLWIFYALWEEMEAKDIDRARQVYTECLKLIPHKKFTFAKVWLMKAQFEVRQLNLQAARKTLGQAIGMCPKDKLFRGYIDLERQLFEFVRCRTLYEKQIEWNPSNSQSWIQYAELERGLDDTERARAIYELGIDQPTLDMPELVWKAYIDFEDDEGEYERERQLYERLLQKTDHVKVWINYARFEINVPDEEEEEEEEERPISDEAKRRARAVFERAHRVFKEKELKEERVELLNAWRAFEHTHGSPEDIDKIEKQMPRRVKKRRKLDDD----RYEEYMDYVFPADDQSAANLSKL---LRMAHQW 664
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Match: A0A4S2LQG4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005583 PE=4 SV=1) HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0 Identity = 330/674 (48.96%), Postives = 462/674 (68.55%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDT---------------------------EEEERFPEVLARSREIFEEANKSLKKMESS-QREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA +QIT+EQLLREAKERELE TPK PQQKI++ +E +++QL+KR+DYE+NIRK++L + NW+KYA FE SQ EI RAR++FERA+++ Y+ V +WLKYAEME++ KQV HARNL++RA+ ++PRANQ WYKY YMEE L NI AR++F+RWM W+P EQAWH++IN E +Y E+++A IY++FV VHP+ +NW+K+AKFEE N + R V A+ F+G+DNP +L EFA+FEERQ+EHER + IYKYALDNLPK ++IY+AY +EKK+GD++ I++ I+ KR+ YE+ + N H+YD WF Y+++MEEE ++D REIYERA+AN P I++K YWRRYIYLW+ YA++EELT N++R +VY CL PHR+FTFAK+W+Y A+ IRQK L ARK LG AIG C K+KL+R YI++E L EFDR R LY KF+ F P W+ +A E L + +R R IYE A+ + LD P +WK+YIDFE + ++E+ L+RR+L++ +H +W S+A +L +T E + + R+R ++ EANK+L+ E QR LL+ WK+FED+YG ES +A P+ +V+ +R+ +E W E FPD + N ++ Sbjct: 25 KNKMPAAIQITAEQLLREAKERELEVTPKAPQQKITSLSELRDFQLRKRKDYEDNIRKNRLAMQNWIKYAKFEESQGEIQRARSIFERALDVDYRNVGLWLKYAEMEMRNKQVNHARNLWDRAVVLMPRANQFWYKYTYMEEMLGNIAGARQVFERWMEWQPEEQAWHAYINFELRYKELDQARMIYERFVLVHPEPRNWVKYAKFEERNGFVNSCRQVFERAVEFFGTDNPQARLLIEFARFEERQKEHERARVIYKYALDNLPKEECQEIYKAYTLHEKKYGDRLAIEDVILSKRKFQYEEEVQANPHNYDVWFDYVRLMEEEG-SVDQTREIYERAVANVPPIKEKRYWRRYIYLWLNYALYEELTVENMERTRQVYRFCLKLIPHRRFTFAKMWLYAAKFEIRQKSLTDARKLLGAAIGMCPKDKLFRGYIELEIQLREFDRCRKLYEKFLEFSPENCTTWMRYAELESLLGEVDRARAIYELAINRPLLDMPELLWKAYIDFEIEQYDWEHARALYRRLLKRTQHVKVWISFANFELCAHNTLTLDDLDDGVEAHLKSANVDKETIIREHNENEVQKGVLRTRAVYREANKALRTCEDKEQRVRLLEAWKEFEDEYGDAESQREIAKLQPQKVVRSRRLGDERS--GWEEFVEYIFPDTDAEKPNQKLL 695
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Match: A0A0R3UJ63 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7525 PE=4 SV=2) HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0 Identity = 324/660 (49.09%), Postives = 458/660 (69.39%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAE-LDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFD-TEEEERFPEVLA------------RSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVI 2016 +NKTPAPVQIT+EQ+LREAK RELE P P QKI+ E +++QL+KR+DYE+NIRK++L + NW+KYA FE SQ E+ RAR++FERA+++ ++ + +WLKYA+ME++ KQV HARNL++RA+ ++PRANQ WYKY YMEE+L NI AR++F+RWM WEP EQAWH++IN E +Y E+++A IY++FV V+P+ KNW+K+AKFEE NN + AR V A+ FYG+DNP + EFA+FEERQ+EH+R + IYKYALDNLP +IY+A+ +EKK+GD++ I+ I+ KR+ YE + N H+YD WF Y+++MEEE +++ RE+YERA+AN P I++K YWRRYIYLWI YA++EELT G+++R EVY+ L PHR+FTFAK+W+Y A+ IRQK L TARK LG A+G+C K KL+R YI++E L EFDR R LY KF+ F P W+ +A E L + ER R IYE A+ LD P +WK+YID+E + +E+ L+RR++++ +H +W S A +L + TE +V A R+RE++ EAN +L+K E QR L+ WK FE++YG +E+ VA P+ +V+ +R+++E G W E FPD + N ++ Sbjct: 25 KNKTPAPVQITAEQILREAKNRELEVAPAAPTQKITNLAELRDFQLRKRKDYEDNIRKNRLAMQNWIKYAKFEESQGELQRARSIFERALDVDFRNIGLWLKYADMEMRNKQVNHARNLWDRAVTLIPRANQFWYKYTYMEEQLGNIVGARQVFERWMEWEPEEQAWHAYINFELRYKELQRARMIYERFVLVNPEPKNWVKYAKFEERNNYINSARQVFERAVEFYGTDNPQARLFIEFARFEERQKEHDRARVIYKYALDNLPSDECPEIYKAFTLHEKKYGDRLAIEGVILNKRKFQYESEVEANPHNYDVWFDYVRLMEEEG-SVEQTRELYERAVANVPPIKEKRYWRRYIYLWINYALYEELTVGDVERTREVYNFALRLIPHRRFTFAKMWLYAAKFEIRQKLLPTARKILGTALGKCPKAKLFRGYIELEIQLREFDRCRKLYEKFLEFSPENCTTWMRYAEMEALLDEVERARAIYELAISQPLLDMPEILWKAYIDYEIEQREWNRARALYRRLMQKTQHVKVWLSLANFELCAQNSTEHGNELGDVGASANETETRAAVERAREVYREANLALRKSNEKEQRVQLIDEWKAFEEEYGDEETQMEVAGFEPQRLVRSRRLEDEAG-GGWEEYVDYIFPDTTAEQPNRKLL 682
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Match: A0A0R3SHV1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS4514 PE=4 SV=1) HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0 Identity = 324/675 (48.00%), Postives = 461/675 (68.30%), Query Frame = 1 Query: 43 NFQASXXXXXXXXRNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAE-LDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEE---------------EERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVI 2016 +F SK+ K KV+NKTPAP+QIT+EQ+LREAK RELE P P QKI+ E +++QL+KR+DYE+NIRK++L + NW+KYA FE SQ E+ RAR++FERA+++ ++ + +WLKYA+ME++ KQV HARNL++RA+ ++PRANQ WYKY YMEE L N+ AR++F+RWM WEP EQAWH++IN E +Y E+++A IY++FV V+P+ KNW+K+AKFEE NN + AR V A+ FYG+DNP + EFA+FEERQ+EH+R + IYKYALDNLP +IY+AY +EKK+GD++ I+ I+ KR+ YE + N H+YD WF Y+++MEEE +++ RE+YERA+AN P +++K YWRRYIYLWI YA +EELT +++R EVY+ L PH+KFTFAK+W+Y A+ IRQK L ARK LG A+G+C K KL+R YI++E L EFDR R LY+KF+ F P W+ +A E L + ER R IYE A+ LD P +WK+YID+E + +E++ L+RR++E+ +H +W S A +L D E E + RSR ++ EAN++L+K E QR L++ WK FE +YG +E+ + VA+ P+ +V+ +R++ W E FPD + N ++ Sbjct: 12 SFDKSKRAKFAKVKNKTPAPIQITAEQILREAKNRELEVAPVAPTQKITNLAELRDFQLRKRKDYEDNIRKNRLAMQNWIKYAKFEESQGELQRARSIFERALDVDFRNIGLWLKYADMEMRNKQVNHARNLWDRAVALIPRANQFWYKYTYMEELLGNVAGARQVFERWMEWEPEEQAWHAYINFELRYKELQRARLIYERFVLVNPEPKNWVKYAKFEERNNYINSARKVFERAVEFYGTDNPQARLFIEFARFEERQKEHDRARVIYKYALDNLPSDECPEIYKAYTLHEKKYGDRLAIEGVILNKRKFQYESEVEANPHNYDVWFDYVRLMEEEG-SVEQTRELYERAVANVPPVKEKRYWRRYIYLWINYAFYEELTVADVERTREVYNFALRLIPHKKFTFAKMWLYAAKFEIRQKQLTAARKLLGTALGKCPKAKLFRGYIELEIQLREFDRCRKLYDKFLEFSPENCTTWMRYAEIEALLDEVERARAIYELAISQPLLDMPEILWKAYIDYEIEQREWDRARALYRRLMEKTQHVKVWLSLANFELCAQDAVEVEEGNADSETAMATNEREGRAAIERSRAVYREANQALRKSPEKEQRVQLIEEWKAFEGEYGNEETRKEVASFEPQRVVRSRRLEEGGAAGGWEEFVEYIFPDTAAEQPNRKLL 685
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Match: A0A158QHU7 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS8091 PE=4 SV=1) HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0 Identity = 324/675 (48.00%), Postives = 464/675 (68.74%), Query Frame = 1 Query: 43 NFQASXXXXXXXXRNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAE-LDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFD----------TEEEERFPE-----VLARSREIFEEANKSLKK-MESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVI 2016 +F SK+ K KV+NKTPAP+QIT+EQ+LREAK RELE P P QKI+ E +++QL+KR+DYE+NIRK++L + NW+KYA FE SQ E+ RAR++FERA+++ ++ + +WLKYA+ME++ KQV HARNL++RA+ ++PRANQ WYKY YMEE L N+ AR++F+RWM WEP EQAWH++IN E +Y E+++A IY++FV V+P+ KNW+K+AKFEE NN + AR V A+ FYG+DNP + EFA+FEERQ+EH+R + IYKYALDNLP +IY+AY +EKK+GD++ I+ I+ KR+ YE N H+YD WF Y+++MEEE +++ RE+YERA+AN P +++K YWRRYIYLWI YA++EELT +++R EVY+ L PH+KFTFAK+W+Y A+ IRQK L ARK LG A+G+C K KL+R YI++E L EFDR R LY+KF+ F P W+ +A E L + ER R IYE A+ LD P +WK+YID+E + +E++ L+RR++E+ +H +W S A +L D E F E + R+R ++ EAN++L+K E QR LL+ WK FE++YG +E+ + V++ P+ +++ +R++ E W E FPD + N ++ Sbjct: 12 SFDKSKRAKFAKVKNKTPAPIQITAEQILREAKNRELEVAPLAPTQKITNLAELRDFQLRKRKDYEDNIRKNRLAMQNWIKYAKFEESQGELQRARSIFERALDVDFRNIGLWLKYADMEMRNKQVNHARNLWDRAVTLIPRANQFWYKYTYMEELLGNVAGARQVFERWMEWEPEEQAWHAYINFELRYKELQRARLIYERFVLVNPEPKNWVKYAKFEERNNYINSARKVFERAIEFYGTDNPQARLFIEFARFEERQKEHDRARVIYKYALDNLPSDECPEIYKAYTLHEKKYGDRLAIEGVILNKRKFQYESEAEANPHNYDVWFDYVRLMEEEG-SVEQTRELYERAVANVPPVKEKRYWRRYIYLWINYALYEELTVADMERTREVYNFALRLIPHKKFTFAKMWLYAAKFEIRQKQLTAARKLLGTALGKCPKAKLFRGYIELEILLREFDRCRKLYDKFLEFSPENCTTWMRYAEMEALLDEVERARAIYELAISQPLLDMPEILWKAYIDYEIEQREWDRARALYRRLMEKTQHVKVWLSLANFELCAQDAIVVEEGSANAETAREFNESEARTAIERARAVYREANQTLRKSSEKEQRVQLLEEWKTFEEEYGNEETRKEVSSFEPQRVIRSRRLEEEGAAGGWEEFVEYIFPDTAAEQPNRKLL 685
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Match: A0A1S8WTJ5 (HAT repeat protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_06402 PE=4 SV=1) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 327/674 (48.52%), Postives = 461/674 (68.40%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDT---------------------------EEEERFPEVLARSREIFEEANKSLKKMESS-QREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA +QIT+EQLLREAKERELE TPK PQQKI++ +E +++QL+KR+DYE+NIRK++L + NW+KYA FE SQ EI RAR++FERA+++ Y+ V +WLKYAEME++ KQV HARNL++RA+ ++PRANQ WYKY YMEE L NI AR++F+RWM W+P EQAWH++IN E +Y E+++A IY++++ +P +NW+K+AKFEE N + R V A+ F+G+DNP +L EFA+FEERQ+EHER + IYKYALDNLPK ++IY+AY +EKK+GD++ I++ I+ KR+ YE+ + N H+YD WF Y+++MEEE ++D REIYERA+AN P I++K YWRRYIYLW+ YA++EELT N++RA +VY CL PHR+FTFAK+W+Y A+ IRQK L ARK LG AIG C K+KL+R YI++E L EFDR R LY KF+ F P W+ +A E L + +R R IYE A+ + LD P +WK+YIDFE + ++E L+RR+L++ +H +W S+A +L +T E + + R+R ++ EANK+L+ E QR LL+ WK+FED+YG ES + +A P+ +V+ +R+ +E W E FPD + N ++ Sbjct: 25 KNKMPAAIQITAEQLLREAKERELEVTPKAPQQKITSLSELRDFQLRKRKDYEDNIRKNRLAMQNWIKYAKFEESQGEIQRARSIFERALDVDYRNVGLWLKYAEMEMRNKQVNHARNLWDRAVVLMPRANQFWYKYTYMEEMLGNIAGARQVFERWMEWQPEEQAWHAYINFELRYKELDQARMIYERYILFYP--RNWVKYAKFEERNGFVNSCRQVFERAVEFFGTDNPQARLLIEFARFEERQKEHERARVIYKYALDNLPKEECQEIYKAYTLHEKKYGDRLAIEDVILSKRKFQYEEEVQANPHNYDVWFDYVRLMEEEG-SVDQTREIYERAVANVPPIKEKRYWRRYIYLWLNYALYEELTVENMERARQVYRFCLKLIPHRRFTFAKMWLYAAKFEIRQKALTDARKLLGAAIGMCPKDKLFRGYIELEIQLREFDRCRKLYEKFLEFSPENCTTWMRYAELESLLGEVDRARAIYELAINRPLLDMPELLWKAYIDFEIEQYDWERARALYRRLLKRTQHVKVWISFANFELCAHNTLTLDDLDDGAEAHLKSANVDKETIIREHNENEVKKGVLRTRAVYREANKALRTCEDKEQRVRLLEAWKEFEDEYGDAESQKEIAKLQPQKVVRSRRLGDERS--GWEEFVEYIFPDTDAEKPNQKLL 693
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:NCBI gene;Acc:103034616]) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 309/648 (47.69%), Postives = 455/648 (70.22%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E E +Y+L+KR+ +E++IRK++ I NW+KYA +E S EI RAR+++ERA+++ ++ V++WLKYAEME++ +QV HARN+++RA+ ILPR NQ WYKY YMEE L N+ R++F+RWM WEP EQAWHS+IN E +Y E++KA IY++FV VHP+ KNWIK+A+FE+ + + AR V A+ F+G ++ ++ FA+FEE+Q+E ERV+ IYKYALD +PK ++++++ Y +EKKFGD+ I++ IV KR+ YE+ + N H+YD WF Y++++ E + ++D +RE+YERAIAN P I++K +WRRYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ + IRQK+L AR+ +G+AIG+C KNKL++ YI++E L EFDR R LY K++ F P WI+FA E L ER R I+E A+ + LD P +WKSYIDFE + +E++ +L++R+L++ +H +W SYAQ + L D+E+ L R R+++EE+NKSL+ E +R MLL+ W+ FE ++GT + + V LP+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 18 KNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDEEELNDYKLRKRKGFEDHIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDHRNVTLWLKYAEMEMKSRQVNHARNIWDRAITILPRVNQFWYKYSYMEEMLGNVAGCRQVFERWMEWEPEEQAWHSYINFELRYKEVDKARTIYERFVIVHPEIKNWIKYARFEDKHGYIAHARKVFERAVEFFGEEHIDENLFVAFARFEEKQKEFERVRVIYKYALDKIPKQQAQELFKNYTVFEKKFGDRRGIEDVIVSKRRFQYEEEVKANPHNYDAWFDYLRLV-ESDADVDTVREVYERAIANMPPIQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYQACLELIPHKKFTFAKIWLLYGQFEIRQKNLQNARRGMGSAIGKCPKNKLFKGYIELELQLREFDRCRKLYEKYLEFGPENCTTWIKFAELETILGDTERARAIFELAIGQPRLDMPEVLWKSYIDFEIEQEEYDKTRELYKRLLQRTQHVKVWISYAQFE-LSVDSEDR------LQRCRQVYEESNKSLRNCEEKEERLMLLESWRDFEQEFGTFANKDRVRKLLPEKVKKRRKLTAEDGSDAGWEEYYDYIFPEDAANQPNLKLL 657
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Match: xab2 (XPA binding protein 2 [Source:NCBI gene;Acc:103039703]) HSP 1 Score: 58.151 bits (139), Expect = 2.914e-8 Identity = 79/362 (21.82%), Postives = 148/362 (40.88%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVL-SENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F ++ AR +FE+A ++YK V ++W +Y EMEL+ + A + +A I R + Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F + +N + + + N KF +R ++ ER +++++ ALD P ++ IY Y + E+++G + YE+ + T + + F+ E + R IY++AI + L ++ + + E G IDRA +YS C + P F + W E IR + T R+ L Sbjct: 393 WVAFARFYEDNEQLEDARTIFEKATKVNYKVVDDLAAVWCEYGEMELRHENYDQALRILRKATAIPARKAE----YFDSSEPVQN-----RVYKSL-------KVWSMLADLEESLGTFQSTKAVYDRIIDLRIATPQIIINYAMFLDEHNYFEESFKAYERGIALFKWPNVYDIWNTYLTKFIDRYGGKKLERARDLFEQALDGCPSKFAKTIYLLYAKLEEEYG--------LARHAMAVYERATQAVETEERLQMFNIYIKRAAEIYGVTHTRAIYQKAI--EILSDEHARDMCLRFADM------ESKLGEIDRARAIYSFCSQMCDPRMTANFWQTW---KEFEIRHGNEDTIREML 719
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Match: prpf39 (pre-mRNA processing factor 39 [Source:NCBI gene;Acc:103021423]) HSP 1 Score: 53.5286 bits (127), Expect = 5.180e-7 Identity = 41/161 (25.47%), Postives = 80/161 (49.69%), Query Frame = 1 Query: 208 EYQLQKRQDYENNIRK--------DKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCI-LPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSF--INLEKKYGEIEKAHAIYKKFVQ 657 E+++ KR +E I++ +K ++ NW +Y FE+ R +FER + W+KYA+ L+ + R++Y++A I LP+ + + + EE+ NI+ AR I K + P A ++LE+++G +++A + + +Q Sbjct: 201 EHEVSKRWAFEEGIKRPYFHVKALEKTQLSNWREYLDFELENGTPERVVVLFERCLIACALYEEFWIKYAKY-LESYSTEGVRHVYKKACTIHLPKKANIHFLWAAFEEQQGNIEEARGILKS-LEESVPGLAMVRLRRVSLERRHGNLDEAETLLRDAIQ 359
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Match: prpf39 (pre-mRNA processing factor 39 [Source:NCBI gene;Acc:103021423]) HSP 1 Score: 53.1434 bits (126), Expect = 8.681e-7 Identity = 41/161 (25.47%), Postives = 80/161 (49.69%), Query Frame = 1 Query: 208 EYQLQKRQDYENNIRK--------DKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCI-LPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSF--INLEKKYGEIEKAHAIYKKFVQ 657 E+++ KR +E I++ +K ++ NW +Y FE+ R +FER + W+KYA+ L+ + R++Y++A I LP+ + + + EE+ NI+ AR I K + P A ++LE+++G +++A + + +Q Sbjct: 410 EHEVSKRWAFEEGIKRPYFHVKALEKTQLSNWREYLDFELENGTPERVVVLFERCLIACALYEEFWIKYAKY-LESYSTEGVRHVYKKACTIHLPKKANIHFLWAAFEEQQGNIEEARGILKS-LEESVPGLAMVRLRRVSLERRHGNLDEAETLLRDAIQ 568
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Match: prpf6 (pre-mRNA processing factor 6 [Source:NCBI gene;Acc:103027632]) HSP 1 Score: 51.9878 bits (123), Expect = 2.356e-6 Identity = 46/205 (22.44%), Postives = 82/205 (40.00%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYL 885 WM+ A +S + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K + ++K K E A+ + T AL Y + P + + EE+ + +E Y L P + Sbjct: 575 TWMEDAESCVSHGALECARAIYAHALQVFPSKKSVWLRAAYFEKSHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAATARVFMKSIKLEWVLGNIDAAQELCTEALRLYENF---PKLWMMKGQIEEQSENMDLAREAYNQGLKKCPHSM 776
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Sea Lamprey
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:ZFIN;Acc:ZDB-GENE-040426-694]) HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0 Identity = 307/649 (47.30%), Postives = 449/649 (69.18%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFV-QVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA +QIT+EQLLREAKERELE P PP+QKIS E E +Y+L+KR+ +E+NIRK++ + NW+KYA +E S EI RAR+++ERA+++ ++ V++WLKYAEME++ +QV HARN+++RA+ ILPR N WYKY YMEE L N+ R++F+RWM WEP EQAWHS+IN E +Y E++ A A+Y+K++ VHP+ KNWIK+A+FE+ + T+ AR V A+ FYG ++ + FA+FEE Q+E +RV+ IYKYALD +PK S+++++ Y +EKK+GD+ I++ IV KR+ YE+ + N H+YD WF Y++++E + + ++ +RE+YERAIAN PL+ +K +WRRYIYLWI +A+FEEL + DR +VY CL PH+KFTF+KIW+ A+ IRQK+L ARK LG +IG+C KNKL++ YI++E L EFDR R LY KF+ F P W++FA E L ER R IYE A+ + LD P +WKSYIDFE + +E L+RR+L++ +H +W S+A+ +L E +ER ++R R ++EE N+SL+ E +R MLL+ W+ FED +G ++S E V +P + +R+++ +DG W E FP+D N+ ++ Sbjct: 19 KNKAPADLQITAEQLLREAKERELELLPPPPRQKISDEEELADYKLRKRKTFEDNIRKNRTVVTNWIKYAQWEESLKEIQRARSLYERALDVDHRNVTLWLKYAEMEMKNRQVNHARNIWDRAVTILPRINAFWYKYTYMEEMLSNVAGCRQVFERWMEWEPEEQAWHSYINFELRYKEVDAARAVYEKYILGVHPEIKNWIKYARFEDRHGYTAHARRVYERAVEFYGEEHMKEPLFVAFARFEEAQKEFDRVRVIYKYALDRIPKQSSQELFKNYTMFEKKYGDRRGIEDVIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDCE-VESVREVYERAIANVPLLPEKRHWRRYIYLWINFALFEELEMKDPDRTRQVYQGCLELIPHKKFTFSKIWLLFAQFEIRQKNLTAARKILGMSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFAPENCTTWMKFAELETILGDVERSRAIYELAVGQPRLDMPEVLWKSYIDFEIEQEECSRTRNLYRRLLQRTQHVKVWISFAKFEL---SVEGKER----VSRCRRVYEEGNRSLRSCEEKEERVMLLEAWRDFEDPFGNEDSRERVQKLMPSRVKKRRKVQTDDGSDAGWEEYYDYIFPEDSANQPNLKLL 659
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Sea Lamprey
Match: prpf6 (PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-030131-2575]) HSP 1 Score: 62.003 bits (149), Expect = 3.714e-10 Identity = 86/439 (19.59%), Postives = 165/439 (37.59%), Query Frame = 1 Query: 325 ARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWM------AWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN----WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKN-KLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 AR + RA+ V +WL A +E ++AR + +A +P +W +EE N KI R + E + W K G + A+ + + + +E++ W++ A ++ AR++ AL + S + A FE+ E ++ + + A+ + PK +E ++ + + GD + + + Q N + + W + +K+ E EN + R + +A ++ P ++ E G I RA E+ + L H F K+W+ K +I + + AR + +C + L+ ++E + + R R + K + P + W+E EYR + + A E +W I EA+ Sbjct: 427 ARILLSRAVECCPTSVELWLALARLE----SYENARKVLNKARENIPTDRHIWITAAKLEEANGNTAMVEKIVDRAITSLRANGVEINREHWIQDAEECDKAGSVTTCQAVIRAVIGIGVEEEDRKHTWMEDADSCVSHGACECARAIYAFALQVFPSKK---SVWLRAAYFEKNHGTRESLEALLQRAVAHCPK--AEVLWLMGAKSKWMAGDVPAARSILALAFQ--------ANPNSEEIWLAAVKL-ESENNEDERARRLLAKARSSAP-----------TARVFMKSVKLEWVLGEIPRAKELSEEALRHYED----FPKLWMMKGQIEEQLQLNDKARDAYSQGLKKCPHSVALWLLLSRLEEHVGQLTRARAILEKARLKNPQNPELWLESVRLEYR-AGLKNIASTLMAKAMQECPSSGILWAEAIFLEAR 831 HSP 2 Score: 52.373 bits (124), Expect = 3.612e-7 Identity = 69/335 (20.60%), Postives = 132/335 (39.40%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A +S AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K K E A+ + AL Y D P ++K + EE+ + +++ ++ Y L P ++ ++ E+ G ++T I+ EK +N + + W +++ E + +I L+ K + AIF E ++++ +C H PH AK++ Sbjct: 550 TWMEDADSCVSHGACECARAIYAFALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWMAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEDERARRLLAKARSSAPTARVFMKSVKLEWVLGEIPRAKELSEEALRHY-EDFPKLWMMK--GQIEEQLQLNDKARDAYSQGLKKCPHSVA--LWLLLSRLEEHVG-QLTRARAIL-------EKARLKNPQNPELWLESVRL--EYRAGLKNIAST---------LMAKAMQECPSSGILWAEAIFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 859
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Sea Lamprey
Match: xab2 (XPA binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-040426-685]) HSP 1 Score: 61.2326 bits (147), Expect = 6.560e-10 Identity = 83/363 (22.87%), Postives = 145/363 (39.94%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTC--GNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A + ++I AR +FE+A + K V +W ++AEMEL+ + A L RA + R Y E ++N +++K + W +LE+ G + A+Y + + + + I +A F E +N + + + N KF ER ++ ER +++++ AL+ P ++ Y Y + E++ G + V +R E + Y + YIK E + R IYE+AI + + F ++ C G IDRA VYS C + P +F + W E I+ + T R+ L Sbjct: 400 WVAFAKYYEENDQIEDARTIFEKATKVALKSVDDLAGVWCEFAEMELRHENYDEALRLLRRATAMPSRKAD----YFDTSEPVQN-----RLYKSL-------KVWSMLADLEESLGTFKSTKAVYDRIIDLRIATPQIIINYAMFLEEHNYFEESYKAYERGIALFRWPNVFDIWNTYLVKFIERYGGKKLERARDLFEQALEGCPPKFAKSFYLLYAKLEEEHG--LARHAMAVYERGTRG----VEPSEQYSMFNIYIKRA-AEIYGVTHTRAIYEKAI----------EVLQDDHAREMCMRFADMECKLGEIDRARAVYSYCSQMSDPRTTLSFWQTW---KEFEIKHGNEDTVREML 726 HSP 2 Score: 50.8322 bits (120), Expect = 9.131e-7 Identity = 55/247 (22.27%), Postives = 108/247 (43.72%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCIL--PRANQLWYKYV--YMEE-KLKNIDSARKIFKRWMAWEPPEQA---WHSFINLEKKYGEIEKAHAIYKKFVQ-VHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGS-----DNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQ 975 W A E S + V++R I++ I + YA + + + YER + + P +W Y+ ++E K ++ AR +F++ + PP+ A + + LE+++G A A+Y++ + V P E+ ++ F R + V T I+ + D+ + FA E + E +R + +Y Y + +Q + E+E K G++ T++E + +KR Sbjct: 489 WSMLADLEESLGTFKSTKAVYDRIIDLRIATPQIIINYAMFLEEHNYFEESYKAYERGIALFRWPNVFDIWNTYLVKFIERYGGKKLERARDLFEQALEGCPPKFAKSFYLLYAKLEEEHGLARHAMAVYERGTRGVEPSEQ----YSMFNIYIKRAAEIYGVTHTRAIYEKAIEVLQDDHAREMCMRFADMECKLGEIDRARAVYSYCSQMSDPRTTLSFWQTWKEFEIKHGNEDTVREMLRIKRS 731
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Sea Lamprey
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 57.3806 bits (137), Expect = 9.871e-9 Identity = 31/147 (21.09%), Postives = 71/147 (48.30%), Query Frame = 1 Query: 235 YENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINI--HYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKR--WMAWEPPEQA--WHSFINLEKKYGEIEKAHAIYKKFVQ 657 Y +R+ + + W+ Y SF + + + AR + +RA+ + V + +K+A+++ + +V+H ++E L P+ +W Y+ M K R +F+R M + P + +++ E+K+G+ + +K ++ Sbjct: 1720 YNKMLRRFRQEKAVWLAYGSFLVQRGQTDSARRLMQRALKSLPEREHVDVIVKFAQLDFRSGEVEHGVAVFENTLSSYPKRTDIWSIYIDMLAKHGTAQQIRAVFERVVHMNFSPKRMKFFFKRYLDYERKHGDAASVQRVRQKALE 1866 HSP 2 Score: 53.5286 bits (127), Expect = 1.854e-7 Identity = 51/251 (20.32%), Postives = 107/251 (42.63%), Query Frame = 1 Query: 376 IWLKYAEMELQCKQVQHARNLYERALCILPRANQ------LWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN-WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNID--DIREIYERAI 1101 +WL+Y LQ +V AR + ERAL + + + +W + +E + S + F+R + +A+ + + ++A +Y K ++ EK W+ + F +T AR ++ AL + ++ +FA+ + R E E +++ L + PK DI+ Y + K G I+ +E+V+ N F + + ++ E ++ D ++ + ++A+ Sbjct: 1626 VWLQYMAFHLQATEVDRARAVAERALKTISFSREEQEKLNVWVALLNLENLYGDEASLMRAFERAVQHNDALKAFRHLAQIYIGSDKFQQADVLYNKMLRRFRQEKAVWLAYGSFLVQRGQTDSARRLMQRALKSL-PEREHVDVIVKFAQLDFRSGEVEHGVAVFENTLSSYPK--RTDIWSIYIDMLAKHGTAQQIRAV--------FERVVHMNFSPKRMKFFFKRYLDYERKHGDAASVQRVRQKAL 1865
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Yeast
Match: CLF1 (Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins [Source:SGD;Acc:S000004107]) HSP 1 Score: 331.643 bits (849), Expect = 3.003e-104 Identity = 209/617 (33.87%), Postives = 330/617 (53.48%), Query Frame = 1 Query: 199 EKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYG--------SDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIAN-KPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLH--TPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELD-----RPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHA-LIWCSYA--------QLQLLDFDTEEEERFPEVL---------ARSREIFEEANKSLKKMESSQ-REMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI 1944 E +EYQ +KR +YE +++++L + W++YA FEI Q+++ RAR++FERA+ + + +W++Y + EL+ K + HARNL RA+ LPR ++LWYKY+ +EE L N++ R ++ +W + EP AW+SF++ E + IY K+V HP + W+KW +FE + T RSV + A+ SD ++ FA +E Q+E+ER +Y+ A++ P ++ + ++EK+FGD +I+ETI KR+ YE +LS N +DYD W+ Y+ ++ E I + +E+AI + +P K + I E Q L+ PH+ FTF+KIW+ A+ IR D+ ARK LG AIG C K K ++ YI++E L EFDRVR +Y KFI F P+ Q W ++ E L ++RVR IY AL D + + YI FE + +EFE KL+RR LE +++ W +A + QLLD + E E + +R++FEEA K+ + Q R +L+ K +E+ YGT+ E V + PK I K++ ++G+ Sbjct: 42 ELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPS--NQLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLISESFPK--QIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVI---KKVRLQNGV 651
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Yeast
Match: RRP5 (RNA binding protein involved in synthesis of 18S and 5.8S rRNAs; component of ribosomal small subunit (SSU) processome and 90S preribosome; required for pre-rRNA packaging and compaction of processome into dense terminal balls; part of Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription with role in biogenesis of large ribosomal subunit; binds single stranded tracts of U's; relocalizes from nucleolus to nucleus upon DNA replication stress [Source:SGD;Acc:S000004842]) HSP 1 Score: 63.1586 bits (152), Expect = 1.149e-10 Identity = 56/265 (21.13%), Postives = 118/265 (44.53%), Query Frame = 1 Query: 337 FERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCIL---PRANQL--WYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN--WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANK 1110 FER + + +W+ Y +LQ +++ AR L ERAL + A +L W + +E ++ ++F R + + + + + +KA ++K + EK W+ W F ++N AR++L AL N ++++FA+ E + + ER + +++ + + PK + D++ Y + E K DK +++ +E+++++ F + K ++ E D+ Y +A A + Sbjct: 1464 FERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRN-HIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRI--DLWNVYVDQEVKAKDKKKVEDL--------FERIITKKITRKQAKFFFNKWLQFEESEGDEKTIEYVKAKATE 1717
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Match: EDO45828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRV5]) HSP 1 Score: 555.444 bits (1430), Expect = 0.000e+0 Identity = 316/667 (47.38%), Postives = 448/667 (67.17%), Query Frame = 1 Query: 25 MNFNDDNFQASXXXXXXXXRNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKMESS-QREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 M +D + KV KV+NK PAPVQIT+EQLLREAKER+LE + PP+QKIS E EY+L+KR+ +E+NIRK++ + NW+KYA +E SQ EI RAR+V+ER++++ ++ ++IWLKYAEME++ +Q+ HARN+++RA+ ILPR NQ WYKY YMEE L NI AR+IF+RWM WEP EQAWHS+IN+E +Y E+E A IY++FV VHPD KNW+K+AKFEE AR V A+ FYG ++ + F KFEE +EH+RV+ IYKYALDNLPK +++Y+++ ++EKK+GDK I+ IV KR+ YE+ + N ++YD WF Y+++ME E ++ +RE+YER+IAN PL +K WRRYIYLWI YA++EEL +I+R VY CL PH KFTFAKIW+ A+ IRQK+LA ARK LG AIG+C K+KL+R YI +E L EFDR R +Y KF+ F P W+++A E L +R R ++E A+ + LD P +WK+YIDFE +EF++ L+ R+L++ H +W SYAQ +L ++R I++ A+K L+ E+ +R +LL+ WK+ ED YG + S + N++P+ + +R+++ +DG W E FPDD N ++ Sbjct: 1 MASSDSGPMGKRVPKVAKVKNKAPAPVQITAEQLLREAKERQLELSLPPPKQKISDPDELAEYKLRKRKAFEDNIRKNRSVVANWLKYAQWEESQQEIQRARSVYERSLDVDHRNITIWLKYAEMEMRHRQINHARNIWDRAVTILPRVNQFWYKYTYMEEMLGNIAGARQIFERWMEWEPEEQAWHSYINMELRYKEVEHARTIYERFVLVHPDVKNWVKFAKFEERQGNIVGARGVYERAVEFYGEEHMDEKLFLAFGKFEEGCKEHDRVRTIYKYALDNLPKEQCQELYKSFTQHEKKYGDKGGIENVIVSKRKFQYEEEVKANPNNYDAWFDYLRLMEAE-ADVSTVRELYERSIANVPLAAEKTLWRRYIYLWINYALYEELMAKDIERTRLVYRACLDVIPHGKFTFAKIWLLYAQFEIRQKNLADARKALGTAIGKCPKDKLFREYIGLELQLREFDRCRKIYEKFLTFNPANCTTWVKYAELESVLGDVDRARALFELAVAQPLLDMPEVLWKAYIDFEINQEEFDHTRDLYERLLKRTNHVKVWISYAQFELTT-------GVEGCTDQARGIYKRADKQLRSAENKEERVLLLESWKELEDSYGDESSQTEMKNRMPRRVKRRRKLQADDGSDAGWEEYYDYIFPDDDTSMPNFKLL 659
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Match: EDO33185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSX5]) HSP 1 Score: 65.4698 bits (158), Expect = 6.104e-11 Identity = 100/484 (20.66%), Postives = 192/484 (39.67%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKR-----------WMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKK-FVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKV---------------------------LSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKN-KLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 W+K A+ E EI+ + V+ +A+ V IW E+E + + AR + RA+ P + +LW +L+ ++ARK+ + W+ E+A ++ +EK IE+A A K V+++ D+ WIK A+ E ++++ T + + H + A +E + IY +AL P S + AY +EK +G + ++ E+++ H K N + + W + +K+ E EN R++ +RA N + +I E GNI A ++ + + P FAK+W+ K ++ ++K+L AR+ + +C + L+ ++E + + R++ + P + W+E E R + + R + A++ E +W I E + Sbjct: 368 WIKAAAVE---TEIVAKKRVYRKALEHIPNSVRIWKAAVELE----EPEDARIMLSRAVECCPTSVELWLALA----RLETYENARKVLNKARENIPTDRLIWITAAKLEEANNNMPMVEKI---IERAVASLKSNGVEINRDQ--WIKDAEECEKAQSVETCQAIIRTVIGVGVEEEDRKHTWMDDADSCVANSAYECSRAIYAHALTVFPSKKSVWLRAAY--FEKNYGTRESL-ESLLQSAVKHCPKAEVLWLMGAKSKWMANDIPSARSILALAFQANPNSEEIWLAAVKL-ESENNEDQRARKLLQRARMN-----------ACTARVMMKSIKLEWVLGNIPEANKLLDEAVQKYPD----FAKLWMMKGQLQEQEKNLPEAREAYKTGVKKCPTSIPLWLLLSRLEEKTGQATKARSVLEQGRQRNPKSPELWLEAVRIETRGGRKDFARTLMAKAMQ-ECPTAGVLWSEAIFMEPR 815 HSP 2 Score: 52.373 bits (124), Expect = 5.601e-7 Identity = 41/180 (22.78%), Postives = 74/180 (41.11%), Query Frame = 1 Query: 220 QKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYME----EKLKNIDS--------------------------ARKIFKRWMAWEPP-EQAWHSFINLEKKYGEIEKAHAIYKKFVQVHP 666 + R+ Y+ ++K I W+ + E + +AR+V E+ + K +WL+ +E + + AR L +A+ P A LW + ++ME K +++D+ AR F R + +P AW F E ++G + ++ K VQV P Sbjct: 719 EAREAYKTGVKKCPTSIPLWLLLSRLEEKTGQATKARSVLEQGRQRNPKSPELWLEAVRIETRGGRKDFARTLMAKAMQECPTAGVLWSEAIFMEPRPQRKTRSVDALKRCEHDAHVLLAVAKLFWSERKVSKARDWFNRAVKLDPDFGDAWAYFYRFELQHGTEAQQESVSHKCVQVEP 898
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Match: EDO38955 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBJ3]) HSP 1 Score: 58.5362 bits (140), Expect = 8.407e-9 Identity = 62/292 (21.23%), Postives = 121/292 (41.44%), Query Frame = 1 Query: 229 QDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAI-NIHYKE----VSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKA----HAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDI 1077 +D++ + + W++Y +F + EI +AR V ERA+ I ++E ++IW+ +E NLY +S K+F+R + P++ + I + + + E A H + K+F Q +K WI++ +F + AR +L L + I+ +FA E + + +R + + + L N PK DI+ Y + K G T+++ +E+V+ N F + K ++ E ++ D++ Sbjct: 1508 EDFDRLVLSSPNNSVTWLQYMAFHLHTTEIDKARAVAERALRTISFREEREKLNIWVALMNLE----------NLYGTQ------------------------ESLIKVFERALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQ---SKKVWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIV-QFALMEFKNGDPQRGQTVLESVLSNYPK--RTDIWSVYIDMMSKQGHPDTVRQI--------FERVIHMNLSSRKMKFLFKKYLDFEREHGDEM 1751 HSP 2 Score: 55.0694 bits (131), Expect = 9.414e-8 Identity = 50/227 (22.03%), Postives = 93/227 (40.97%), Query Frame = 1 Query: 439 YERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAW----EPPEQ--AWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAI 1101 ++R + P + W +Y+ ID AR + +R + E E+ W + +NLE YG E ++++ +Q + +K + + +T +A + T + + EF +F + + + +++ + L +LP + + E K GD Q + E VLS D W YI MM ++ D +R+I+ER I Sbjct: 1510 FDRLVLSSPNNSVTWLQYMAFHLHTTEIDKARAVAERALRTISFREEREKLNIWVALMNLENLYGTQESLIKVFERALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQSK---KVWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIVQFALMEFKNGDPQRGQTVL--------ESVLSNYPKRTDIWSVYIDMMSKQGHP-DTVRQIFERVI 1724
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Match: EDO33251 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSQ6]) HSP 1 Score: 51.6026 bits (122), Expect = 7.644e-7 Identity = 43/199 (21.61%), Postives = 90/199 (45.23%), Query Frame = 1 Query: 235 YENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKL-----KNIDSARKIFKRWMAWEP----PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSD--NPPPHILKE 798 Y +++++ +W F +N++ AR F+ + W KYA+ME + ++ A+ ++E+ + + + LW Y+ + + R++F+R +A ++ W ++I EK G++++ A+Y K V P + + KF+E N VA + T L+ ++ PP ++ E Sbjct: 2 YWKSVKENPSDFTSWTYLLQFVEQENKLSSARKAFQTFFKRYPYCYGYWKKYADMERKNGNIEAAKEVFEQGVKAIACSVDLWVHYLNFSSQATKGQPDGPEIMRRLFERAIATAGQDFRSDKLWDAYIEWEKSQGQLQRVTALYDKLFTV-PTQNYAQHFEKFKEHINTHPVASVLQTEELLKLRAEVAAAPPGVISE 199
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Match: EDO29782 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2N5]) HSP 1 Score: 49.6766 bits (117), Expect = 1.605e-6 Identity = 61/292 (20.89%), Postives = 120/292 (41.10%), Query Frame = 1 Query: 229 QDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAI-NIHYKE----VSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKA----HAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDI 1077 +D++ + + W++Y +F + EI +AR V ERA+ I ++E ++IW+ +E NLY +S K+F+R + P++ + I + + + E A H + K+F Q + WI++ +F + AR +L L + I+ +FA E + + +R + + + L N PK DI+ Y + K G T+++ +E+V+ N F + K ++ E ++ D++ Sbjct: 11 EDFDRLVLSSPNNSVTWLQYMAFHLHTTEIDKARAVAERALRTISFREEREKLNIWVALMNLE----------NLY------------------------GTQESLIKVFERALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQ---SKTVWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIV-QFALMEFKNGDPQRGQTVLESVLSNYPK--RTDIWSVYIDMMSKQGHPDTVRQI--------FERVIHMNLSSRKMKFLFKKYLDFEREHGDEM 254 HSP 2 Score: 48.521 bits (114), Expect = 3.845e-6 Identity = 50/227 (22.03%), Postives = 93/227 (40.97%), Query Frame = 1 Query: 439 YERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAW----EPPEQA--WHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAI 1101 ++R + P + W +Y+ ID AR + +R + E E+ W + +NLE YG E ++++ +Q + +K + + +T +A + T + + EF +F + + + +++ + L +LP + + E K GD Q + E VLS D W YI MM ++ D +R+I+ER I Sbjct: 13 FDRLVLSSPNNSVTWLQYMAFHLHTTEIDKARAVAERALRTISFREEREKLNIWVALMNLENLYGTQESLIKVFERALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQSKT---VWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIVQFALMEFKNGDPQRGQTVL--------ESVLSNYPKRTDIWSVYIDMMSKQGHP-DTVRQIFERVI 227
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:NCBI gene;Acc:101164119]) HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0 Identity = 315/648 (48.61%), Postives = 451/648 (69.60%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E +Y+L+KR+ +E+NIRK++ I NW+KYA +E SQ E+ RAR+++ERA+++ ++ +++WLKYAEME++ +QV HARN+++RA+ ILPR NQ WYKY YMEE L N+ R+ F+RWM WEP EQAWHS+IN E +Y E++KA IY++FV VHP+ KNWIK+A+FEE + + +R V A FYG D+ ++ FAKFEE Q+E ERV+ IYKYALD +PK ++++++ Y +EKKFGD+ I++ I+ KR+ YE+ + N +YD WF Y++++E + + D +R++YERAIAN P I++K +WRRYIYLWI YA++EEL + +R +VY CL PH+KFTFAKIW+ A+ IRQK+L ARK +G AIG+C KNKL + YI++E L EFDR R LY K++ F P WI+FA E L ER R I+E A+ + LD P +WKSYIDFE + +EFEN L++R+L++ +H +W SYA+ + L D P+ LA+ R+IFEEANKS++ E +R MLL+ W+ +E ++G+D S E V+ LP+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 18 KNKAPADVQITAEQLLREAKERELELLPPPPKQKITNAEELNDYKLRKRKAFEDNIRKNRTIISNWIKYAQWEESQKEVQRARSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNVAGCRQAFERWMEWEPDEQAWHSYINFELRYKEVDKARTIYERFVMVHPEVKNWIKYARFEEKHGYIAHSRKVYERAAEFYGEDHVNENLFVAFAKFEEMQKEFERVRVIYKYALDKIPKNQAQELFKNYTMFEKKFGDRRGIEDVIINKRRFQYEEEVKANPLNYDAWFDYLRLVESDG-DPDTVRDVYERAIANIPPIQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYQACLDLMPHKKFTFAKIWLLFAQFEIRQKNLQAARKIMGTAIGKCPKNKLLKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDVERSRAIFELAIGQPRLDMPEVLWKSYIDFEIEQEEFENTRNLYKRLLQRTQHVKVWISYAKFE-LSVDG------PDRLAKCRQIFEEANKSMRNCEEKEERLMLLESWRDYEKEFGSDSSRERVSKLLPEKVKKRRKLTAEDGSDAGWEEYYDYIFPEDAANQPNLKLL 657
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:NCBI gene;Acc:101164119]) HSP 1 Score: 539.265 bits (1388), Expect = 0.000e+0 Identity = 307/655 (46.87%), Postives = 444/655 (67.79%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHP-------DEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E +Y+L+KR+ +E+NIRK++ I NW+KYA +E SQ E+ RAR+++ERA+++ ++ +++WLKYAEME++ +QV HARN+++RA+ ILPR NQ WYKY YMEE L N+ R+ F+RWM WEP EQAWHS+IN E +Y E++KA IY++++ +H E NWIK+A+FEE + + +R V A FYG D+ ++ FAKFEE Q+E ERV+ IYKYALD +PK ++++++ Y +EKKFGD+ I++ I+ KR+ YE+ + N +YD WF Y++++E + + D +R++YERAIAN P I++K +WRRYIYLWI YA++EEL + ++ CLL KFTFAKIW+ A+ IRQK+L ARK +G AIG+C KNKL + YI++E L EFDR R LY K++ F P WI+FA E L ER R I+E A+ + LD P +WKSYIDFE + +EFEN L++R+L++ +H +W SYA+ + L D P+ LA+ R+IFEEANKS++ E +R MLL+ W+ +E ++G+D S E V+ LP+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 19 KNKAPADVQITAEQLLREAKERELELLPPPPKQKITNAEELNDYKLRKRKAFEDNIRKNRTIISNWIKYAQWEESQKEVQRARSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNVAGCRQAFERWMEWEPDEQAWHSYINFELRYKEVDKARTIYERYILLHHLFDHFDLTETNWIKYARFEEKHGYIAHSRKVYERAAEFYGEDHVNENLFVAFAKFEEMQKEFERVRVIYKYALDKIPKNQAQELFKNYTMFEKKFGDRRGIEDVIINKRRFQYEEEVKANPLNYDAWFDYLRLVESDG-DPDTVRDVYERAIANIPPIQEKRHWRRYIYLWINYALYEELEV----KVGSSFTSCLLS----KFTFAKIWLLFAQFEIRQKNLQAARKIMGTAIGKCPKNKLLKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDVERSRAIFELAIGQPRLDMPEVLWKSYIDFEIEQEEFENTRNLYKRLLQRTQHVKVWISYAKFE-LSVDG------PDRLAKCRQIFEEANKSMRNCEEKEERLMLLESWRDYEKEFGSDSSRERVSKLLPEKVKKRRKLTAEDGSDAGWEEYYDYIFPEDAANQPNLKLL 657
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Match: crnkl1 (crooked neck pre-mRNA splicing factor 1 [Source:NCBI gene;Acc:101164119]) HSP 1 Score: 527.324 bits (1357), Expect = 1.531e-178 Identity = 299/648 (46.14%), Postives = 431/648 (66.51%), Query Frame = 1 Query: 82 RNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAAL-KAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKM-ESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGI-PTWIESSSLEFPDDVQQDHNMSVI 2016 +NK PA VQIT+EQLLREAKERELE P PP+QKI+ E +Y+L+KR+ +E+NIRK++ I NW+KYA +E SQ E+ RAR+++ERA+++ ++ +++WLKYAEME++ +QV HARN+++RA+ ILPR NQ WYKY YMEE L N+ R+ F+RWM WEP EQAWHS+IN E +Y E++KA IY++FV VHP+ KNWIK+A+FEE + + +R V A FYG D+ ++ FAKFEE Q+E ERV+ IYKYALD +PK ++++++ Y +EKKFGD+ I++ I+ KR+ YE+ + N +YD WF Y++++E + + D +R++YERAIAN P I++K +WRRYIYLWI YA++EEL + +R +VY CL PH+K G AIG+C KNKL + YI++E L EFDR R LY K++ F P WI+FA E L ER R I+E A+ + LD P +WKSYIDFE + +EFEN L++R+L++ +H +W SYA+ + L D P+ LA+ R+IFEEANKS++ E +R MLL+ W+ +E ++G+D S E V+ LP+ + +R+++ EDG W E FP+D N+ ++ Sbjct: 18 KNKAPADVQITAEQLLREAKERELELLPPPPKQKITNAEELNDYKLRKRKAFEDNIRKNRTIISNWIKYAQWEESQKEVQRARSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNVAGCRQAFERWMEWEPDEQAWHSYINFELRYKEVDKARTIYERFVMVHPEVKNWIKYARFEEKHGYIAHSRKVYERAAEFYGEDHVNENLFVAFAKFEEMQKEFERVRVIYKYALDKIPKNQAQELFKNYTMFEKKFGDRRGIEDVIINKRRFQYEEEVKANPLNYDAWFDYLRLVESDG-DPDTVRDVYERAIANIPPIQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYQACLDLMPHKK---------------------------GTAIGKCPKNKLLKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDVERSRAIFELAIGQPRLDMPEVLWKSYIDFEIEQEEFENTRNLYKRLLQRTQHVKVWISYAKFE-LSVDG------PDRLAKCRQIFEEANKSMRNCEEKEERLMLLESWRDYEKEFGSDSSRERVSKLLPEKVKKRRKLTAEDGSDAGWEEYYDYIFPEDAANQPNLKLL 630
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Match: prpf6 (pre-mRNA processing factor 6 [Source:NCBI gene;Acc:101162926]) HSP 1 Score: 63.5438 bits (153), Expect = 6.183e-10 Identity = 84/439 (19.13%), Postives = 168/439 (38.27%), Query Frame = 1 Query: 325 ARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWM------AWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKN----WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKN-KLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAK 1608 AR + RA+ V +WL A +E ++AR + +A +P +W +EE N KI R + E W K G + A+ + + + +E++ W++ A + AR++ AL + S + A FE+ E ++ + + A+ + PK +E ++ + + GD + + + Q N + + W + +K+ E EN + R + +A ++ P ++ E GNI+ A ++ ++ L H F K+W+ + +I + +++ AR+ + +C + L+ ++E + + R R + K + P W+E EYR + AL+ E +W + EA+ Sbjct: 447 ARIMLSRAVECCPTSVELWLALARLE----TYENARRVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINRDQWIQDAEECDKAGSVATCQAVIRAVIGIGIEEEDRKHTWMEDADSCVAHGALECARAIYAHALQVFPSKK---SVWLRAAYFEKNHGTRESLEALLQRAVAHCPK--AEVLWLMGAKSKWLAGDVPAARSILALAFQ--------ANPNSEEIWLAAVKL-ESENNEYERARRLLAKARSSAP-----------TARVFMKSVKLEWVLGNIEAAQDLCTEALKHYED----FPKLWMMRGQIEEQCENMDKAREAYNQGLKKCPHSVALWFLLSRLEERVGQLTRARAILEKSRLKNPQCADLWLESVRLEYRAGLKNIANTLMAKALQ-ECPNSGILWAEAVFLEAR 851 HSP 2 Score: 57.3806 bits (137), Expect = 4.967e-8 Identity = 71/335 (21.19%), Postives = 134/335 (40.00%), Query Frame = 1 Query: 274 NWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEP-PEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIW 1275 WM+ A ++ + AR ++ A+ + + S+WL+ A E + L +RA+ P+A LW + ++ +AR I P E+ W + + LE + E E+A + K P + ++K K E A+ + T AL Y D P +++ + EE+ ++ +E Y L P ++ ++ E++ G ++T I+ EK +N D W +++ E + + IAN L+ K + A+F E ++++ +C H PH AK++ Sbjct: 570 TWMEDADSCVAHGALECARAIYAHALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNIEAAQDLCTEALKHY-EDFPKLWMMR--GQIEEQCENMDKAREAYNQGLKKCPHSVA--LWFLLSRLEERVG-QLTRARAIL-------EKSRLKNPQCADLWLESVRL--EYRAGLKN--------IANT-LMAKALQECPNSGILWAEAVFLEARPQRKTKSVDALKKC-EHDPHVLLAVAKLF 879
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Match: xab2 (XPA binding protein 2 [Source:NCBI gene;Acc:101157537]) HSP 1 Score: 60.077 bits (144), Expect = 7.170e-9 Identity = 87/361 (24.10%), Postives = 152/361 (42.11%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEV----SIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVH-PDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEER--QREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCL-LHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTL 1335 W+ +A F ++ AR +FE+A +++K+V ++W +Y EMEL+ + Y++AL IL +A + K K + DS+ + R + W +LE+ G + A+Y + + + + I +A F E +N + + + N KF +R ++ ER +++++ ALD P ++ IY Y + E+++G + V +R + V E H + YIK E + R IY++AI P + R+ + E G IDRA +YS C + P F + W E IR + T R+ L Sbjct: 393 WVCFAKFYEENEQLDDARTIFEKATKVNFKQVDDLAAVWCEYGEMELRHEN-------YDQALRILRKATAIPSK------KAEYFDSSEPVQNRVYK---SLKVWSMLADLEESLGTFQSTKAVYDRIIDLRIATPQIIINYAMFLEEHNYFEESFKAYERGIALFKWPNVYDIWNTYLTKFIDRYGGKKLERARDLFEQALDGCPAKFAKTIYLLYAKLEEEYG--LARHAMAVYERAT--QAVEPEERHHM--FNIYIKRA-AEIYGVTYTRAIYQKAIEVLPDEHARDMCLRFADM--------ESKLGEIDRARAIYSYCSQICDPRLTANFWQTW---KEFEIRHGNEDTIREML 719 HSP 2 Score: 53.9138 bits (128), Expect = 5.638e-7 Identity = 57/246 (23.17%), Postives = 109/246 (44.31%), Query Frame = 1 Query: 277 WMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCIL--PRANQLWYKYV--YMEE-KLKNIDSARKIFKRWMAWEPPEQA---WHSFINLEKKYGEIEKAHAIYKKFVQ-VHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGS-----DNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKR 972 W A E S + V++R I++ I + YA + + + YER + + P +W Y+ +++ K ++ AR +F++ + P + A + + LE++YG A A+Y++ Q V P+E++ + F R + V T I+ + D + FA E + E +R + IY Y L+ + +Q + E+E + G++ TI+E + +KR Sbjct: 482 WSMLADLEESLGTFQSTKAVYDRIIDLRIATPQIIINYAMFLEEHNYFEESFKAYERGIALFKWPNVYDIWNTYLTKFIDRYGGKKLERARDLFEQALDGCPAKFAKTIYLLYAKLEEEYGLARHAMAVYERATQAVEPEERHHM----FNIYIKRAAEIYGVTYTRAIYQKAIEVLPDEHARDMCLRFADMESKLGEIDRARAIYSYCSQICDPRLTANFWQTWKEFEIRHGNEDTIREMLRIKR 723
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Planmine SMEST
Match: SMESG000006174.1 (SMESG000006174.1) HSP 1 Score: 1305.43 bits (3377), Expect = 0.000e+0 Identity = 676/678 (99.71%), Postives = 678/678 (100.00%), Query Frame = 1 Query: 25 MNFNDDNFQASXXXXXXXXRNKTPAPVQITSXXXXXXXXXXXXXXTPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKMESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVIDDFLKNVQNWDISI 2058 MNFNDDNFQASKKTKVTKVRNKTPAPVQITSEQLLREAKERELEATPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEE+NNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKYYWRRYIYLWIRYAIFEELTCGNIDRAIEVYSQCLLHTPH+KFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKMESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVIDDFLKNVQNWDISI Sbjct: 1 MNFNDDNFQASKKTKVTKVRNKTPAPVQITSEQLLREAKERELEATPKPPQQKISTETEKKEYQLQKRQDYENNIRKDKLKIINWMKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEKLKNIDSARKIFKRWMAWEPPEQAWHSFINLEKKYGEIEKAHAIYKKFVQVHPDEKNWIKWAKFEESNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSEDIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMMEEENQNIDDIREIYERAIANKPLIEKKYYWRRYIYLWIRYAIFEELTCGNIDRAIEVYSQCLLHTPHKKFTFAKIWIYKAEIHIRQKDLATARKTLGNAIGRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIYEAALKAELDRPYYVWKSYIDFEAKIKEFENCWKLHRRILEQEEHALIWCSYAQLQLLDFDTEEEERFPEVLARSREIFEEANKSLKKMESSQREMLLKFWKKFEDDYGTDESIEYVANKLPKTIVQRKRIDNEDGIPTWIESSSLEFPDDVQQDHNMSVIDDFLKNVQNWDISI 678
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Planmine SMEST
Match: SMESG000011657.1 (SMESG000011657.1) HSP 1 Score: 50.447 bits (119), Expect = 4.962e-6 Identity = 95/458 (20.74%), Postives = 189/458 (41.27%), Query Frame = 1 Query: 280 MKYASFEISQNEILRARNVFERAINIHYKEVSIWLKYAEMELQCKQVQHARNLYERALCILPRANQLWYKYVYMEEK---LKNIDSARKIFKRWMAWEPPEQA-WHSFINLE-----------KKYGEIEKAHAIYKKFVQVHPDEKN------------------WIKWAKFEETNNRTSVARSVLTTALIFYGSDNPPPHILKEFAKFEERQREHERVKEIYKYALDNLPKYLSE---DIYQAYCEYEKKFGDKMTIQETIVMKRQHHYEKVLSENTHDYDEWFSYIKMME--EENQNIDDIREIYERAIANKPLIEKKXXXXXXXXXXXXXAIFEELTCGNIDRAIEVYSQCLLHTPHRKFTFAKIWIYKAEIHIRQKDLATARKTLGNAI-GRCGKNKLYRYYIKMETDLLEFDRVRTLYNKFIVFYPTYEQAWIEFANFEYRLKQFERVRYIY 1536 M + E++ +I ++R + + + + +VS W+ E ++ A+ L + P + ++W + + + ++ NI A+ + + + P + W + NLE + EI + ++K V++ D + W+ AK N + AR+VL TA +D I K EE + E+++ + + A++ L + E D + E +K G+K+T Q+ I ++V+S + D +++ E EE+ ++ R IY AI++ L +KK +W R A FE+ G + ++ SQ + H T +W+ A+ D+ +AR L A ++ +K+E++ EFDR L + + T ++ W++ A E+ L + + Sbjct: 257 MNPSGSEVA--DIKKSRLLLKSMTDTNPHKVSGWISIVRFEEHFSKIHEAKQLVMKGCENCPESEEMWMEAIRIMKQYGGTDNISQAKSVASKAIKQVPNSVSLWVAAANLEETLKTKRVVYKRALAEIPDSVKLWKLIVELEDDPEEAKQLLEGAVQCCPTSVELWLALAKL----NNPTEARAVLNTARQKIPNDR---QIWITACKLEEAEGNDEKIERLIQRAIEVLKSNMVEINRDEWIKDAEEAEKSGNKVTAQKII--------QRVVSIGVDEQDRKQTWLADAEACEEHGCLECARAIYSIAISS--LSKKK-------GIWKRAAAFEK-EHGTRENYEKILSQAVEHCD----TVEVLWLMAAKSKWEAGDVESARNVLSRAFAANPNSEEIMLAAVKLESENNEFDRANRLLQRARMNVGT-DRVWMKSARLEWCLGNLDSAETLL 682 The following BLAST results are available for this feature:
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Crooked neck pre-mRNA splicing factor 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033191 ID=SMED30033191|Name=Crooked neck pre-mRNA splicing factor 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2100bpback to top protein sequence of SMED30033191-orf-1 >SMED30033191-orf-1 ID=SMED30033191-orf-1|Name=SMED30033191-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=679bp MNFNDDNFQASKKTKVTKVRNKTPAPVQITSEQLLREAKERELEATPKPPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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