Peregrin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033182 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Peregrin vs. Ensembl Human
Match: BRPF1 (bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]) HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0 Identity = 287/641 (44.77%), Postives = 392/641 (61.15%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSI 2516 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ Sbjct: 132 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSL 753
BLAST of Peregrin vs. Ensembl Human
Match: BRPF1 (bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]) HSP 1 Score: 554.673 bits (1428), Expect = 4.820e-177 Identity = 290/653 (44.41%), Postives = 395/653 (60.49%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ EDA Sbjct: 132 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 765 HSP 2 Score: 122.865 bits (307), Expect = 1.635e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 988 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1110
BLAST of Peregrin vs. Ensembl Human
Match: BRPF1 (bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]) HSP 1 Score: 556.214 bits (1432), Expect = 1.490e-176 Identity = 290/653 (44.41%), Postives = 395/653 (60.49%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ EDA Sbjct: 132 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 765 HSP 2 Score: 123.25 bits (308), Expect = 1.492e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1082 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1204
BLAST of Peregrin vs. Ensembl Human
Match: BRPF1 (bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]) HSP 1 Score: 556.214 bits (1432), Expect = 1.643e-176 Identity = 290/653 (44.41%), Postives = 395/653 (60.49%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ EDA Sbjct: 132 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 765 HSP 2 Score: 123.25 bits (308), Expect = 1.493e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1083 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1205
BLAST of Peregrin vs. Ensembl Human
Match: BRPF1 (bromodomain and PHD finger containing 1 [Source:HGNC Symbol;Acc:HGNC:14255]) HSP 1 Score: 555.829 bits (1431), Expect = 5.363e-176 Identity = 290/653 (44.41%), Postives = 395/653 (60.49%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ EDA Sbjct: 130 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 763 HSP 2 Score: 122.865 bits (307), Expect = 1.806e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1115 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1237
BLAST of Peregrin vs. Ensembl Celegans
Match: lin-49 (pep chromosome:WBcel235:IV:8620683:8626149:1 gene:WBGene00003034.1 transcript:F42A9.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-49) HSP 1 Score: 281.567 bits (719), Expect = 1.601e-78 Identity = 171/529 (32.33%), Postives = 272/529 (51.42%), Query Frame = 3 Query: 903 VEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDE--DAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN---VGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRR-XXXXXXXXXXXXXXIDEGSSEMISNLKFWQQ---IRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQ 2462 V+Y +DE D+ W+ N T L I A E+ +DR EK C ++ L ++ E D VC++CLDG N N I++CD CNL+VHQ+CYG+P++PEG CR+C SP+ V+C LCP+ GAFKQ + RW HV+C +W+ E F N IF+E ++NVEK R L+C LCK + +GACIQC ++ C +FHVTCA+ +GL M+I ++E + + +C H+P ++D E+ RQ L++ R+ N+R+ IS P + +K + I V + I +W KR R G PLL+ +S L S G + + + +Q +++ L + ++ +RE+ K+++ ++I + + PT L +++I+ L+T+D GK+FAEPV Y+ II+ P+ + +K S +Y + L D LM+SNC +N N +Y + R +S P+ E E++ Sbjct: 133 VDYSVDEFDMSWMSIMNAKRTKLGL-----------------EIFSVAIYEHWVDRLEKMCIWKPKEFHKLKDENGEELDDVCNICLDGDTSNCNQIVYCDRCNLSVHQDCYGIPFIPEGCLECRRCGISPAGRVNCVLCPSTTGAFKQVDQKRWVHVLCVIWVDETHFGNTIFMENVQNVEKALHDRRALSCLLCKNRQNARMGACIQCSETKCTASFHVTCARDSGLVMRINETED----GQVNRFVWCPKHAPP----------LTDADREM-------RQLMLRNARR-ENERKGPM--ISMPTL----MKSMISTICVERPFSDYSEIIYFWYEKRLNRLGAPLLKNFTQGASKSRRLLPKSTICGQLKNVETCEMKKQVNAVKESLASGLEIFDMIVRREERKKDMLNSYIRMFERGFKPTELLCQEVIEALKTIDAGKVFAEPVELV---GYTDIIENPICLKDMSEKAASGKYSTVAALSADVQLMLSNCATFNKGNRVYIKYGNTYRKDSTPILEIAEKE 613
BLAST of Peregrin vs. Ensembl Celegans
Match: phf-15 (PHd Finger family [Source:UniProtKB/TrEMBL;Acc:Q9N3F6]) HSP 1 Score: 130.954 bits (328), Expect = 1.103e-30 Identity = 61/160 (38.12%), Postives = 90/160 (56.25%), Query Frame = 3 Query: 1122 DIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQ--WLCRKCLHSPSHPVDCCLCPNKGGAFKQTND-NRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQ 1592 D EDA CDVC CD ++ ++FCD+CN VH C G+ +P+ W C KC H + C LCP GG+ + D +WAH C L+IPEI+F N P+ + E++ RW C +C + GAC+ C +C +HV CA +AG+ ++I++ Sbjct: 274 DGGEDAECDVCRISDCDVADEMVFCDMCNTCVHMVCAGIEELPDPAEPWKCAKCAHMGTPCPPCVLCPALGGSMTYSADKTQWAHHSCALFIPEIIFENEELRAPMTSFERVAEERWSQMCSVCDTRQ-GACVTCSWVDCEETYHVCCALRAGMTVRIQE 432
BLAST of Peregrin vs. Ensembl Celegans
Match: phf-15 (PHd Finger family [Source:UniProtKB/TrEMBL;Acc:Q9N3F6]) HSP 1 Score: 130.183 bits (326), Expect = 1.380e-30 Identity = 61/160 (38.12%), Postives = 90/160 (56.25%), Query Frame = 3 Query: 1122 DIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQ--WLCRKCLHSPSHPVDCCLCPNKGGAFKQTND-NRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQ 1592 D EDA CDVC CD ++ ++FCD+CN VH C G+ +P+ W C KC H + C LCP GG+ + D +WAH C L+IPEI+F N P+ + E++ RW C +C + GAC+ C +C +HV CA +AG+ ++I++ Sbjct: 233 DGGEDAECDVCRISDCDVADEMVFCDMCNTCVHMVCAGIEELPDPAEPWKCAKCAHMGTPCPPCVLCPALGGSMTYSADKTQWAHHSCALFIPEIIFENEELRAPMTSFERVAEERWSQMCSVCDTRQ-GACVTCSWVDCEETYHVCCALRAGMTVRIQE 391
BLAST of Peregrin vs. Ensembl Celegans
Match: zfp-1 (Uncharacterized protein F54F2.2, isoform a [Source:UniProtKB/Swiss-Prot;Acc:P34447]) HSP 1 Score: 130.183 bits (326), Expect = 2.732e-30 Identity = 65/159 (40.88%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKCLHSPS-------HPVDCC-LCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNV-----GACIQCHKSNCYTAFHVTCAQQAGL 1574 C VC D N +++CD C +AVHQ CYG+ VPEG+W C KC + + CC LCP GA K+T+ N WAHV+C L+IPE+ F N+ +EP+ + + ++ CY+C ++ GAC+ C+KS C +FHVTCAQ+ GL Sbjct: 8 CCVCADENGWTDNPLIYCDGENCEVAVHQGCYGIQEVPEGEWFCAKCTKASAMMPGSINEATFCCQLCPFDYGALKKTDRNGWAHVICALYIPEVRFGNVHSMEPVI-LNDVPTDKFNKLCYICNEERPNDAKKGACMSCNKSTCKRSFHVTCAQRKGL 165
BLAST of Peregrin vs. Ensembl Celegans
Match: zfp-1 (Uncharacterized protein F54F2.2, isoform a [Source:UniProtKB/Swiss-Prot;Acc:P34447]) HSP 1 Score: 130.183 bits (326), Expect = 2.732e-30 Identity = 65/159 (40.88%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKCLHSPS-------HPVDCC-LCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNV-----GACIQCHKSNCYTAFHVTCAQQAGL 1574 C VC D N +++CD C +AVHQ CYG+ VPEG+W C KC + + CC LCP GA K+T+ N WAHV+C L+IPE+ F N+ +EP+ + + ++ CY+C ++ GAC+ C+KS C +FHVTCAQ+ GL Sbjct: 8 CCVCADENGWTDNPLIYCDGENCEVAVHQGCYGIQEVPEGEWFCAKCTKASAMMPGSINEATFCCQLCPFDYGALKKTDRNGWAHVICALYIPEVRFGNVHSMEPVI-LNDVPTDKFNKLCYICNEERPNDAKKGACMSCNKSTCKRSFHVTCAQRKGL 165
BLAST of Peregrin vs. Ensembl Fly
Match: Br140 (gene:FBgn0033155 transcript:FBtr0089021) HSP 1 Score: 517.309 bits (1331), Expect = 3.211e-160 Identity = 249/560 (44.46%), Postives = 355/560 (63.39%), Query Frame = 3 Query: 819 EYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG--IRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGS---SEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGF 2480 +Y + P Y +++EK+ EELD VEYD+DEED WL NE L + V TME ++DR EKE HF++ G+ ++D+DAVC +CLDG C N+NVILFCD+CNLAVHQ+CYGVPY+PEGQWLCR+CL SPS PV+C LCPN GGAFKQT+ +WAHVVC LWIPE+ FAN +FLEPI+++E I ARWRL CY+CK+K +GACIQCH+++CY AFHVTCAQQAGLYM ++ + + ++K A+C H+P+ K ++ + ++ + K+K+ RK L K+R+ + P IPP++++EI + ++ K+EF++RI AYW +KR YR+GVPLLRRL + + + + EGS E+ LK+WQ +RQDLE+ARLL EL RKREK+K R + L P + L+D L+ D+ +IF EPV + P+Y+ I++ PMD +R K K +Y ++E+L DFDLM+ NC YN ++T++Y ++R ++ P+F + ++ G Sbjct: 194 DYRVSDAPPRPLAYYRFIEKSLEELDGEVEYDVDEEDSAWLEHMNEERQRLGL-----------------NAVGIDTMELLMDRLEKESHFQAAANGTPTGVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLKMNVPDFEDT------------RHKMKEARKALAKKRSTAPVVLIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGL 724 HSP 2 Score: 114.39 bits (285), Expect = 4.106e-25 Identity = 54/113 (47.79%), Postives = 73/113 (64.60%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRH 3494 LEPL LVWAKCRGYPW+P LI+DP + G N VP+P PP +V L + ++ FLVLFFD KRTWQWL KL+ + + +D+ L K + K+V +AY+DA+ + Sbjct: 1303 LEPLQLVWAKCRGYPWYPALILDP-KTPKGFVYNGVPLPAPPTDVLALRKNCLDEIVFLVLFFDVKRTWQWLPANKLDILGIDKQLDQQKLVESRKPAERKAVKKAYQDALHY 1414
BLAST of Peregrin vs. Ensembl Fly
Match: Br140 (gene:FBgn0033155 transcript:FBtr0345370) HSP 1 Score: 517.309 bits (1331), Expect = 3.211e-160 Identity = 249/560 (44.46%), Postives = 355/560 (63.39%), Query Frame = 3 Query: 819 EYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG--IRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGS---SEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGF 2480 +Y + P Y +++EK+ EELD VEYD+DEED WL NE L + V TME ++DR EKE HF++ G+ ++D+DAVC +CLDG C N+NVILFCD+CNLAVHQ+CYGVPY+PEGQWLCR+CL SPS PV+C LCPN GGAFKQT+ +WAHVVC LWIPE+ FAN +FLEPI+++E I ARWRL CY+CK+K +GACIQCH+++CY AFHVTCAQQAGLYM ++ + + ++K A+C H+P+ K ++ + ++ + K+K+ RK L K+R+ + P IPP++++EI + ++ K+EF++RI AYW +KR YR+GVPLLRRL + + + + EGS E+ LK+WQ +RQDLE+ARLL EL RKREK+K R + L P + L+D L+ D+ +IF EPV + P+Y+ I++ PMD +R K K +Y ++E+L DFDLM+ NC YN ++T++Y ++R ++ P+F + ++ G Sbjct: 194 DYRVSDAPPRPLAYYRFIEKSLEELDGEVEYDVDEEDSAWLEHMNEERQRLGL-----------------NAVGIDTMELLMDRLEKESHFQAAANGTPTGVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLKMNVPDFEDT------------RHKMKEARKALAKKRSTAPVVLIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGL 724 HSP 2 Score: 114.39 bits (285), Expect = 4.106e-25 Identity = 54/113 (47.79%), Postives = 73/113 (64.60%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRH 3494 LEPL LVWAKCRGYPW+P LI+DP + G N VP+P PP +V L + ++ FLVLFFD KRTWQWL KL+ + + +D+ L K + K+V +AY+DA+ + Sbjct: 1303 LEPLQLVWAKCRGYPWYPALILDP-KTPKGFVYNGVPLPAPPTDVLALRKNCLDEIVFLVLFFDVKRTWQWLPANKLDILGIDKQLDQQKLVESRKPAERKAVKKAYQDALHY 1414
BLAST of Peregrin vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0305549) HSP 1 Score: 198.364 bits (503), Expect = 9.949e-51 Identity = 144/443 (32.51%), Postives = 198/443 (44.70%), Query Frame = 3 Query: 909 YDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-----GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNR-WAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMK--IEQSEKISGPAGIRKSAFCDVHSPSGYK---AGVSRGMYANSDEEL-----------------------TSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDN------IDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFR 2117 YD+D D WL N + RA P ++ E VI+ E C +E I L + DE+ +CDVC + +N ++FCD CN+ VHQ CYG+ +P GQWLCR C S DC LCPNKGGA K + WAHV C LWIPE+ + +EPI + I +RW L C LC+ K VG+CIQC C TA+HVTCA Q GL M+ IE+ G++ ++C HS S K AG G A+ + T E P +R+ K +L ++ RN + E K + N DV ++ + I+ YWK+KR+ R L+ D + N K +RQDLE+ R L + +REK+ R LF+ Sbjct: 250 YDIDPIDEAWLRLYN---------------SDRAQCGAFP--INATQFERVIEELEVRC-WEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTC--SMGIKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAED---GVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKT--ELTSEERNQARAQRLQEVEAEFDKHVNFNDISCHLFDV--DDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMIARKQEQQD------MENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFK 658
BLAST of Peregrin vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0305548) HSP 1 Score: 198.364 bits (503), Expect = 9.949e-51 Identity = 144/443 (32.51%), Postives = 198/443 (44.70%), Query Frame = 3 Query: 909 YDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-----GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNR-WAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMK--IEQSEKISGPAGIRKSAFCDVHSPSGYK---AGVSRGMYANSDEEL-----------------------TSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDN------IDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFR 2117 YD+D D WL N + RA P ++ E VI+ E C +E I L + DE+ +CDVC + +N ++FCD CN+ VHQ CYG+ +P GQWLCR C S DC LCPNKGGA K + WAHV C LWIPE+ + +EPI + I +RW L C LC+ K VG+CIQC C TA+HVTCA Q GL M+ IE+ G++ ++C HS S K AG G A+ + T E P +R+ K +L ++ RN + E K + N DV ++ + I+ YWK+KR+ R L+ D + N K +RQDLE+ R L + +REK+ R LF+ Sbjct: 250 YDIDPIDEAWLRLYN---------------SDRAQCGAFP--INATQFERVIEELEVRC-WEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTC--SMGIKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAED---GVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKT--ELTSEERNQARAQRLQEVEAEFDKHVNFNDISCHLFDV--DDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMIARKQEQQD------MENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFK 658
BLAST of Peregrin vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0072532) HSP 1 Score: 198.364 bits (503), Expect = 9.949e-51 Identity = 144/443 (32.51%), Postives = 198/443 (44.70%), Query Frame = 3 Query: 909 YDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-----GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNR-WAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMK--IEQSEKISGPAGIRKSAFCDVHSPSGYK---AGVSRGMYANSDEEL-----------------------TSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDN------IDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFR 2117 YD+D D WL N + RA P ++ E VI+ E C +E I L + DE+ +CDVC + +N ++FCD CN+ VHQ CYG+ +P GQWLCR C S DC LCPNKGGA K + WAHV C LWIPE+ + +EPI + I +RW L C LC+ K VG+CIQC C TA+HVTCA Q GL M+ IE+ G++ ++C HS S K AG G A+ + T E P +R+ K +L ++ RN + E K + N DV ++ + I+ YWK+KR+ R L+ D + N K +RQDLE+ R L + +REK+ R LF+ Sbjct: 250 YDIDPIDEAWLRLYN---------------SDRAQCGAFP--INATQFERVIEELEVRC-WEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTC--SMGIKPDCVLCPNKGGAMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAED---GVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKT--ELTSEERNQARAQRLQEVEAEFDKHVNFNDISCHLFDV--DDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMIARKQEQQD------MENHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFK 658
BLAST of Peregrin vs. Ensembl Zebrafish
Match: brpf3b (bromodomain and PHD finger containing, 3b [Source:ZFIN;Acc:ZDB-GENE-081104-468]) HSP 1 Score: 547.74 bits (1410), Expect = 2.035e-173 Identity = 303/736 (41.17%), Postives = 434/736 (58.97%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEIL-SNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEK-ETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIE--QSEKISGPA-GIRKSAFCDVHSPS--------------GYKAGVSRGMYANSDE--------ELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRR-XXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF----ANKSIYDLVINSTFED 2549 L+YA ++K V + D R R ++ P+ + ++++ I E N+N ENS TS S + S+ +R R + K +++L+ S+ + +T+ N + P P F E E++E E P Y +Y++K++E+ D EYD+DEED+ WL NE + S P I T E +IDR EKE ES + ++ + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEPIE V+ I ARW+L CYLCKQK GA IQCHK+NCYTAFHVTCAQ+AGL+MKI+ + ++G ++K+AFC+ HSP+ G +A R Y + E ++ S++P K+ KK ++V K + T ++ P IP ++L +I+ ++ ++ K +FM R+H YW +KR+ R+GVPL+RR + + DE + + LK+WQ++R DLE+ARLL EL RKREK+KRE + ++ + L P + L+ +++LQ DT KIFA+PV P+Y + I PMDF+ ++ K ++++Y ++ L DF+LM+SNC YNA++T++Y A +LR + +RQ GFD +TG+ NK+ Y TFED Sbjct: 47 LTYAQAQKIVEVDLDGRLHRISIFDPLVVITEDEMTAQDIAECNSN---KENSEQTSVSTVVSSPRRSVANRGKK------KDVKQLSSSQNHCSNSHGQSQTQSSGNSHHGTL---PKPTFKEH---EFYEPVEAPPRPSAYYRYIDKSSEDPDTDAEYDMDEEDVAWLELVNE----------------KRDSDGQPHISPD-TFELLIDRLEKESFLESRSQASSQSVIDEDAFCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPIEGVDNIPPARWKLTCYLCKQKGCGASIQCHKANCYTAFHVTCAQRAGLFMKIDPVRETTVNGTTFSVKKTAFCEAHSPAVNGSDDEETGGRVLGCRANRGRSAYMQTPELKKQKGSNKVDSKQPQKKGKK-EEVSK-----KTTTLLVTVPEIPAQRLNKISKDVIIQKKNQFMQRLHNYWLLKRQSRNGVPLIRRLHSHLQGQRSAEQAEPDEKLNAVREELKYWQKLRHDLERARLLIELIRKREKLKREQVKIHQAVTEHQLTPVLVLLSSTLEQLQEKDTAKIFAQPVNLKEVPDYLEFITHPMDFSTMQSKLEAHKYRSVTDLEADFNLMISNCLLYNAKDTVFYQAAIRLRDLGGAILRHAQRQAQNTGFDLDTGMHLAESPNKNDY---YRCTFED 741 HSP 2 Score: 119.398 bits (298), Expect = 1.236e-26 Identity = 58/119 (48.74%), Postives = 75/119 (63.03%), Query Frame = 3 Query: 3159 EPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 EPLDLVWAK RGYP +P LI+DP M +G+ N VPIP PP +V LG + + + FLVLFFD KRTWQWL ++K+ P V + D+ + K+ KSV AY A++HL V Sbjct: 1092 EPLDLVWAKSRGYPSYPALIIDPDMPQDGLLHNGVPIPVPPLDVLRLGEQRQEEAGERLFLVLFFDNKRTWQWLSKDKVIPLGVDDTTDKLRIMEGKKTSIRKSVQVAYDRAMKHLSRV 1210
BLAST of Peregrin vs. Ensembl Zebrafish
Match: brpf3b (bromodomain and PHD finger containing, 3b [Source:ZFIN;Acc:ZDB-GENE-081104-468]) HSP 1 Score: 546.969 bits (1408), Expect = 3.066e-173 Identity = 303/736 (41.17%), Postives = 434/736 (58.97%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEIL-SNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEK-ETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIE--QSEKISGPA-GIRKSAFCDVHSPS--------------GYKAGVSRGMYANSDE--------ELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRR-XXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF----ANKSIYDLVINSTFED 2549 L+YA ++K V + D R R ++ P+ + ++++ I E N+N ENS TS S + S+ +R R + K +++L+ S+ + +T+ N + P P F E E++E E P Y +Y++K++E+ D EYD+DEED+ WL NE + S P I T E +IDR EKE ES + ++ + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEPIE V+ I ARW+L CYLCKQK GA IQCHK+NCYTAFHVTCAQ+AGL+MKI+ + ++G ++K+AFC+ HSP+ G +A R Y + E ++ S++P K+ KK ++V K + T ++ P IP ++L +I+ ++ ++ K +FM R+H YW +KR+ R+GVPL+RR + + DE + + LK+WQ++R DLE+ARLL EL RKREK+KRE + ++ + L P + L+ +++LQ DT KIFA+PV P+Y + I PMDF+ ++ K ++++Y ++ L DF+LM+SNC YNA++T++Y A +LR + +RQ GFD +TG+ NK+ Y TFED Sbjct: 47 LTYAQAQKIVEVDLDGRLHRISIFDPLVVITEDEMTAQDIAECNSN---KENSEQTSVSTVVSSPRRSVANRGKK------KDVKQLSSSQNHCSNSHGQSQTQSSGNSHHGTL---PKPTFKEH---EFYEPVEAPPRPSAYYRYIDKSSEDPDTDAEYDMDEEDVAWLELVNE----------------KRDSDGQPHISPD-TFELLIDRLEKESFLESRSQASSQSVIDEDAFCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPIEGVDNIPPARWKLTCYLCKQKGCGASIQCHKANCYTAFHVTCAQRAGLFMKIDPVRETTVNGTTFSVKKTAFCEAHSPAVNGSDDEETGGRVLGCRANRGRSAYMQTPELKKQKGSNKVDSKQPQKKGKK-EEVSK-----KTTTLLVTVPEIPAQRLNKISKDVIIQKKNQFMQRLHNYWLLKRQSRNGVPLIRRLHSHLQGQRSAEQAEPDEKLNAVREELKYWQKLRHDLERARLLIELIRKREKLKREQVKIHQAVTEHQLTPVLVLLSSTLEQLQEKDTAKIFAQPVNLKEVPDYLEFITHPMDFSTMQSKLEAHKYRSVTDLEADFNLMISNCLLYNAKDTVFYQAAIRLRDLGGAILRHAQRQAQNTGFDLDTGMHLAESPNKNDY---YRCTFED 741 HSP 2 Score: 119.398 bits (298), Expect = 1.330e-26 Identity = 58/119 (48.74%), Postives = 75/119 (63.03%), Query Frame = 3 Query: 3159 EPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 EPLDLVWAK RGYP +P LI+DP M +G+ N VPIP PP +V LG + + + FLVLFFD KRTWQWL ++K+ P V + D+ + K+ KSV AY A++HL V Sbjct: 1086 EPLDLVWAKSRGYPSYPALIIDPDMPQDGLLHNGVPIPVPPLDVLRLGEQRQEEAGERLFLVLFFDNKRTWQWLSKDKVIPLGVDDTTDKLRIMEGKKTSIRKSVQVAYDRAMKHLSRV 1204
BLAST of Peregrin vs. Ensembl Zebrafish
Match: brpf3a (bromodomain and PHD finger containing, 3a [Source:ZFIN;Acc:ZDB-GENE-130530-730]) HSP 1 Score: 493.426 bits (1269), Expect = 2.380e-158 Identity = 255/594 (42.93%), Postives = 350/594 (58.92%), Query Frame = 3 Query: 855 GYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKA------GVSRGMYANSDEELTSEKP----------GKRQKKLKDVRKLLNKRRNYTAPISF-PVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL-FANKSI-YDLVINSTFEDAHIYQL 2567 Y +Y+EK+ EELD EYD+DEED+ WL N+ +R S + V T E +IDR E+E ES + + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS PVDC LCPN+GGAFKQT+D WAHV+C +WIPE+ FAN +FLEP+E V+ I ARW+L CYLCKQK GA IQCHK+NCY AFHVTCAQ+AGLYMKI+ + +G G ++K+A+C+ HSP G G+ G T P G ++ K + R P+ P IP +L +I + V K +FM R+H YW +KR R+GVPL+RRL + D + LK+WQ++RQDLEKARLL EL RKRE++KRE + + + L P + ++ +++L+ DT IF PV P+Y + + PMDF+ + K ++++Y ++ L DF+LM+SNC RYN+ +T+++ A +LR + + Q IG D TG+ +K I ++ ++ E H+++L Sbjct: 159 AYYRYMEKSGEELDNEAEYDMDEEDMAWLEMVNQ---------------KRVSDGH--ASVPPDTFELLIDRLERESILESRSQALSQSTIDEDAYCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGSWAHVICAIWIPEVCFANTVFLEPVEGVKNIPPARWKLTCYLCKQKGRGASIQCHKANCYRAFHVTCAQRAGLYMKIDPVRE-TGTNGTTFTVKKTAYCENHSPPGTGTEGYEDNGLVGGRGNRGQRSYTLGPPLQQNQNGRKKGSAAQQKKTQKNSGGGSRKTGVPLLLVPQIPSFRLNKICTGVSVERKNQFMQRLHNYWLLKRHSRNGVPLIRRLHSHLQAQKSEQREPDAKLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQAALELQLTPALVFLRATLEQLKEKDTDHIFTTPVNLKEVPDYLEFVTVPMDFSTMHDKLEAHKYSSVADLENDFNLMVSNCLRYNSNDTVFHKAAMQLREVGGAILRHAQHQALSIGLDPSTGMHLPDKPIPHNTTVSWCDEGEHLHKL 734
BLAST of Peregrin vs. Ensembl Zebrafish
Match: brpf3a (bromodomain and PHD finger containing, 3a [Source:ZFIN;Acc:ZDB-GENE-130530-730]) HSP 1 Score: 493.426 bits (1269), Expect = 2.380e-158 Identity = 255/594 (42.93%), Postives = 350/594 (58.92%), Query Frame = 3 Query: 855 GYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKA------GVSRGMYANSDEELTSEKP----------GKRQKKLKDVRKLLNKRRNYTAPISF-PVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL-FANKSI-YDLVINSTFEDAHIYQL 2567 Y +Y+EK+ EELD EYD+DEED+ WL N+ +R S + V T E +IDR E+E ES + + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS PVDC LCPN+GGAFKQT+D WAHV+C +WIPE+ FAN +FLEP+E V+ I ARW+L CYLCKQK GA IQCHK+NCY AFHVTCAQ+AGLYMKI+ + +G G ++K+A+C+ HSP G G+ G T P G ++ K + R P+ P IP +L +I + V K +FM R+H YW +KR R+GVPL+RRL + D + LK+WQ++RQDLEKARLL EL RKRE++KRE + + + L P + ++ +++L+ DT IF PV P+Y + + PMDF+ + K ++++Y ++ L DF+LM+SNC RYN+ +T+++ A +LR + + Q IG D TG+ +K I ++ ++ E H+++L Sbjct: 159 AYYRYMEKSGEELDNEAEYDMDEEDMAWLEMVNQ---------------KRVSDGH--ASVPPDTFELLIDRLERESILESRSQALSQSTIDEDAYCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGSWAHVICAIWIPEVCFANTVFLEPVEGVKNIPPARWKLTCYLCKQKGRGASIQCHKANCYRAFHVTCAQRAGLYMKIDPVRE-TGTNGTTFTVKKTAYCENHSPPGTGTEGYEDNGLVGGRGNRGQRSYTLGPPLQQNQNGRKKGSAAQQKKTQKNSGGGSRKTGVPLLLVPQIPSFRLNKICTGVSVERKNQFMQRLHNYWLLKRHSRNGVPLIRRLHSHLQAQKSEQREPDAKLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQAALELQLTPALVFLRATLEQLKEKDTDHIFTTPVNLKEVPDYLEFVTVPMDFSTMHDKLEAHKYSSVADLENDFNLMVSNCLRYNSNDTVFHKAAMQLREVGGAILRHAQHQALSIGLDPSTGMHLPDKPIPHNTTVSWCDEGEHLHKL 734
BLAST of Peregrin vs. Ensembl Zebrafish
Match: brpf3a (bromodomain and PHD finger containing, 3a [Source:ZFIN;Acc:ZDB-GENE-130530-730]) HSP 1 Score: 493.426 bits (1269), Expect = 4.077e-156 Identity = 257/603 (42.62%), Postives = 348/603 (57.71%), Query Frame = 3 Query: 753 KNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKA------GVSRGMYANSDEELT----------SEKPGKRQKKLKDVRKLLNKRRNYTAPISF-PVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +N EQ K P+P + + P Y +Y+EK+ EELD EYD+DEED+ WL N+ +R S + V T E +IDR E+E ES + + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS PVDC LCPN+GGAFKQT+D WAHV+C +WIPE+ FAN +FLEP+E V+ I ARW+L CYLCKQK GA IQCHK+NCY AFHVTCAQ+AGLYMKI+ + +G G ++K+A+C+ HSP G G+ G T K G ++ K + R P+ P IP +L +I + V K +FM R+H YW +KR R+GVPL+RRL + D + LK+WQ++RQDLEKARLL EL RKRE++KRE + + + L P + ++ +++L+ DT IF PV P+Y + + PMDF+ + K ++++Y ++ L DF+LM+SNC RYN+ +T+++ A +LR + + Q IG D TG+ Sbjct: 82 ENSEQSKKKDAPLPKPTFRKLDNFTVSDAPPLPVAYYRYMEKSGEELDNEAEYDMDEEDMAWLEMVNQ---------------KRVSDGH--ASVPPDTFELLIDRLERESILESRSQALSQSTIDEDAYCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGSWAHVICAIWIPEVCFANTVFLEPVEGVKNIPPARWKLTCYLCKQKGRGASIQCHKANCYRAFHVTCAQRAGLYMKIDPVRE-TGTNGTTFTVKKTAYCENHSPPGTGTEGYEDNGLVGGRGNRGQRSYTLGPPLQQNQNGRKKGSAAQQKKTQKNSGGGSRKTGVPLLLVPQIPSFRLNKICTGVSVERKNQFMQRLHNYWLLKRHSRNGVPLIRRLHSHLQAQKSEQREPDAKLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQAALELQLTPALVFLRATLEQLKEKDTDHIFTTPVNLKEVPDYLEFVTVPMDFSTMHDKLEAHKYSSVADLENDFNLMVSNCLRYNSNDTVFHKAAMQLREVGGAILRHAQHQALSIGLDPSTGM 666 HSP 2 Score: 127.487 bits (319), Expect = 3.712e-29 Identity = 63/126 (50.00%), Postives = 79/126 (62.70%), Query Frame = 3 Query: 3138 SQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLH---SNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 SQ++ +EPL LVWAKCRGYP +P +IVDP M GI N +PIP PP +V +LG+ S + FLVLFFD KRTWQWL ++KL + + +DR L K KSVH AY A+ HL V Sbjct: 792 SQNDGEMEPLTLVWAKCRGYPSYPAMIVDPKMPQEGILHNGIPIPVPPTDVLDLGKRRQEESEEKLFLVLFFDTKRTWQWLPQDKLHHMGIDDTVDRLRLMEGKKPNVRKSVHTAYDRAMTHLSHV 917
BLAST of Peregrin vs. Ensembl Xenopus
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100127652]) HSP 1 Score: 560.451 bits (1443), Expect = 3.226e-178 Identity = 325/845 (38.46%), Postives = 468/845 (55.38%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNV--NVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMIS-NLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDA------MAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVIN-----STFEDAHIYQLEKEL 2579 +D DV F +R KPP+ CP + C K+++S+S I HL H + + I K + SA + P S+ + ++YA +++ V ++ R R ++ N+ + +S D+D E N + EN NDT + S + KRK S ++ + E+ ++ E LE + P Y +Y+EK+AEELDE VEYD+DEED IWL N +RR + + + Q EY++DR EKE +FES + ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL + + ++ LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ ++ LQ DT IF EPV + P+Y + ++ PMDF +++ ++ Y N ++ DF+L+++NC +YNA++TI+Y AS+LR + + + +Q ++IG D ETG+ + I I + FE AH+ K+L Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKIYKSYSGIEYHLY--HYDHDNPPLQQQTPIRKSKK--------KGRHPRSANKQSPTNSEVSQSPTREV-MTYAQAQRLVEVELHGRVHRISIFDNLDV-VSEDDD----PPEETPENGSNKEN-NDTPATTPKSGKHKNKDKRKDSNHHHHHSATAGAATKLPEV-------------------------VYRE---LELDSPDAPPRPSSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMN---------------DRRKNDGV--NHIPQEIFEYLMDRLEKESYFESHNKGDPNSLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSVCKLPALSHSEGEEEDDEEEEDGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQNDPTDKNWVLKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQMALEMQLTPFLILLRKTLELLQEKDTSNIFTEPVPLSEVTEIYEVPDYLEHVKKPMDFQTMKRNLEAFRYQNFDQFEEDFNLIVNNCIKYNAKDTIFYRAASRLREQGAALLRQARKQAEKIGIDFETGMHIHPVITGNEIGRHEAPNNFERAHLSDSRKQL 783 HSP 2 Score: 102.449 bits (254), Expect = 2.887e-21 Identity = 60/124 (48.39%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP +V +LG + +H +LVLFFD KRTWQWL R KL P + ++D+ + KS KSV AY A++H V +P Sbjct: 1087 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHHGVPIPVPPVDVLKLGEQMAQEAQEHLYLVLFFDNKRTWQWLPRTKLVPLGMNRELDKEKMLEGRKSNIRKSVQIAYDRAMQHRNKVQGDP 1210
BLAST of Peregrin vs. Ensembl Xenopus
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100127652]) HSP 1 Score: 553.132 bits (1424), Expect = 5.643e-175 Identity = 330/880 (37.50%), Postives = 472/880 (53.64%), Query Frame = 3 Query: 135 MDDIDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNV--NVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-------DEGSSEM----ISN----------------------LKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDA------MAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVIN-----STFEDAHIYQLEKEL 2579 M +D DV F +R KPP+ CP + C K+++S+S I HL H + + I K + SA + P S+ + ++YA +++ V ++ R R ++ N+ + +S D+D E N + EN NDT + S + KRK S ++ + E+ ++ E LE + P Y +Y+EK+AEELDE VEYD+DEED IWL N +RR + + + Q EY++DR EKE +FES + ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL + D+ + ISN LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ ++ LQ DT IF EPV + P+Y + ++ PMDF +++ ++ Y N ++ DF+L+++NC +YNA++TI+Y AS+LR + + + +Q ++IG D ETG+ + I I + FE AH+ K+L Sbjct: 1 MMGVDFDVKTFCHNLRATKPPYECPVETCRKIYKSYSGIEYHLY--HYDHDNPPLQQQTPIRKSKK--------KGRHPRSANKQSPTNSEVSQSPTREV-MTYAQAQRLVEVELHGRVHRISIFDNLDV-VSEDDD----PPEETPENGSNKEN-NDTPATTPKSGKHKNKDKRKDSNHHHHHSATAGAATKLPEV-------------------------VYRE---LELDSPDAPPRPSSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMN---------------DRRKNDGV--NHIPQEIFEYLMDRLEKESYFESHNKGDPNSLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSVCKLPALSHSEGEEEDDEEEEDGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQEMKWRIPISDDTPGHLGTIAISNEEPGDQANKNDPTDKNWVLKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQMALEMQLTPFLILLRKTLELLQEKDTSNIFTEPVPLSEVTEIYEVPDYLEHVKKPMDFQTMKRNLEAFRYQNFDQFEEDFNLIVNNCIKYNAKDTIFYRAASRLREQGAALLRQARKQAEKIGIDFETGMHIHPVITGNEIGRHGRENDFERAHLSDSRKQL 816 HSP 2 Score: 102.834 bits (255), Expect = 2.715e-21 Identity = 60/124 (48.39%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP +V +LG + +H +LVLFFD KRTWQWL R KL P + ++D+ + KS KSV AY A++H V +P Sbjct: 1120 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHHGVPIPVPPVDVLKLGEQMAQEAQEHLYLVLFFDNKRTWQWLPRTKLVPLGMNRELDKEKMLEGRKSNIRKSVQIAYDRAMQHRNKVQGDP 1243
BLAST of Peregrin vs. Ensembl Xenopus
Match: tf (transferrin [Source:Xenbase;Acc:XB-GENE-480506]) HSP 1 Score: 527.324 bits (1357), Expect = 1.996e-168 Identity = 290/704 (41.19%), Postives = 411/704 (58.38%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPA---GIRKSAFCDVHSPSG-------------YKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX-XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 L+YA +++ V ++ + R R ++ P+ I ++DL I E N+N ENS Q L S KR ++ K ++ PE K + V++ P P+ Y K+ +K+ EELD+ VEYD+DEED WL NE +R S S V Q E+++DRFEKE + E+ + + IDEDAVC +C+DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL S + P+DC LCPNKGGAFK+T+D+RW HVVC LWIPE+ FAN +F+EPI+ V I ARW+L CYLCKQK VGACIQCHK+NCYTAFHVTCAQ+AGLYMK+E ++++G ++K+A+CD H+P G K G+ R +SD+ + S +R K +K LN+ N I+ P IPP+++ +I + + + K++F+ R+H+YW +KR R+G+PLLRRL +S + DE + LK+ Q++R DLE+ARLL EL RKREK+KRE + + L P L++ L+++LQ D +IFA PV P+Y I+ PMDF+ ++K+ + Y N+ DF+L++ NC +YNA++TI+Y A +LR + + R+ + IGFD+ETG+ Sbjct: 31 LTYAQAQRMVEIEIEGRLHRISIFDPLEIVSEDDLTAQEINECNSNK---ENSEQPPQVCLRS-------KRHKASKEKKKSEVLPTAHGHTTTSVLPEPKVR---------VIECSPP-------------SAPNRSPSYYKFQDKSPEELDKEVEYDMDEEDYAWLEIINE---------------KRKSEGF--SAVSQDIFEFLMDRFEKESYCENQKQGDQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRNIPIDCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKEVAGSITTFSVKKTAYCDAHTPPGCVRRPLNIYEEPESKNGICR---KSSDKNIRSTSKARR--KTTKAKKELNETCNVLPTITVPDIPPQRVNKIINQVSIPRKKQFIERVHSYWMLKRLSRNGIPLLRRLQSSLQSQRNIQESEDDEEVQALKKKLKYLQRLRHDLERARLLIELIRKREKLKREQVKVEQVAMELKLTPLTVLLRSLLEQLQEKDPARIFAHPVNLTEVPDYLDHIKHPMDFSTMKKRLEDQRYRNLNEFEEDFNLIIENCMKYNAKDTIFYRAAVRLRDHGGVLLRQARREANVIGFDEETGM 680 HSP 2 Score: 109.383 bits (272), Expect = 1.740e-23 Identity = 56/131 (42.75%), Postives = 75/131 (57.25%), Query Frame = 3 Query: 3132 IKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 + + ++ LEPL +VWAKC GYP +P LI+DP M G N V IP PP +V + G + + + FLVLFFD KR+WQWL + K+ P V E ID+ + S K+V AY A+ HL V E Sbjct: 826 VAASTSAFLEPLKVVWAKCSGYPSYPALIIDPKMPRVGCHHNGVAIPVPPMDVLKTGDQMQTRAEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRVAYDRALNHLSRVQGE 956
BLAST of Peregrin vs. Ensembl Xenopus
Match: tf (transferrin [Source:Xenbase;Acc:XB-GENE-480506]) HSP 1 Score: 526.939 bits (1356), Expect = 1.261e-167 Identity = 290/704 (41.19%), Postives = 412/704 (58.52%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPA---GIRKSAFCDVHSPSG-------------YKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMI-SNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 L+YA +++ V ++ + R R ++ P+ I ++DL I E N+N ENS Q L S KR ++ K ++ PE K + V++ P P+ Y K+ +K+ EELD+ VEYD+DEED WL NE +R S S V Q E+++DRFEKE + E+ + + IDEDAVC +C+DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL S + P+DC LCPNKGGAFK+T+D+RW HVVC LWIPE+ FAN +F+EPI+ V I ARW+L CYLCKQK VGACIQCHK+NCYTAFHVTCAQ+AGLYMK+E ++++G ++K+A+CD H+P G K G+ R +SD+ + S +R K +K LN+ N I+ P IPP+++ +I + + + K++F+ R+H+YW +KR R+G+PLLRRL +S S D+ + + LK+ Q++R DLE+ARLL EL RKREK+KRE + + L P L++ L+++LQ D +IFA PV P+Y I+ PMDF+ ++K+ + Y N+ DF+L++ NC +YNA++TI+Y A +LR + + R+ + IGFD+ETG+ Sbjct: 31 LTYAQAQRMVEIEIEGRLHRISIFDPLEIVSEDDLTAQEINECNSNK---ENSEQPPQVCLRS-------KRHKASKEKKKSEVLPTAHGHTTTSVLPEPKVR---------VIECSPP-------------SAPNRSPSYYKFQDKSPEELDKEVEYDMDEEDYAWLEIINE---------------KRKSEGF--SAVSQDIFEFLMDRFEKESYCENQKQGDQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRNIPIDCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKEVAGSITTFSVKKTAYCDAHTPPGCVRRPLNIYEEPESKNGICR---KSSDKNIRSTSKARR--KTTKAKKELNETCNVLPTITVPDIPPQRVNKIINQVSIPRKKQFIERVHSYWMLKRLSRNGIPLLRRLQSSLQSQRNIQESEDDEEVQALKKKLKYLQRLRHDLERARLLIELIRKREKLKREQVKVEQVAMELKLTPLTVLLRSLLEQLQEKDPARIFAHPVNLTEVPDYLDHIKHPMDFSTMKKRLEDQRYRNLNEFEEDFNLIIENCMKYNAKDTIFYRAAVRLRDHGGVLLRQARREANVIGFDEETGM 680 HSP 2 Score: 111.694 bits (278), Expect = 4.373e-24 Identity = 64/165 (38.79%), Postives = 89/165 (53.94%), Query Frame = 3 Query: 3033 HESQDVDDEDSTQDNSNNIFDSFDASEEDETE-GIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 H +D + S +N N + A+E +T + + ++ LEPL +VWAKC GYP +P LI+DP M G N V IP PP +V + G + + + FLVLFFD KR+WQWL + K+ P V E ID+ + S K+V AY A+ HL V E Sbjct: 847 HTIEDRSELISCIENGNYARAARIAAEVGQTNMWVAASTSAFLEPLKVVWAKCSGYPSYPALIIDPKMPRVGCHHNGVAIPVPPMDVLKTGDQMQTRAEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRVAYDRALNHLSRVQGE 1011
BLAST of Peregrin vs. Ensembl Xenopus
Match: tf (transferrin [Source:Xenbase;Acc:XB-GENE-480506]) HSP 1 Score: 528.48 bits (1360), Expect = 1.264e-166 Identity = 290/704 (41.19%), Postives = 411/704 (58.38%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPA---GIRKSAFCDVHSPSG-------------YKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXX-XXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 L+YA +++ V ++ + R R ++ P+ I ++DL I E N+N ENS Q L S KR ++ K ++ PE K + V++ P P+ Y K+ +K+ EELD+ VEYD+DEED WL NE +R S S V Q E+++DRFEKE + E+ + + IDEDAVC +C+DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL S + P+DC LCPNKGGAFK+T+D+RW HVVC LWIPE+ FAN +F+EPI+ V I ARW+L CYLCKQK VGACIQCHK+NCYTAFHVTCAQ+AGLYMK+E ++++G ++K+A+CD H+P G K G+ R +SD+ + S K ++K +K LN+ N I+ P IPP+++ +I + + + K++F+ R+H+YW +KR R+G+PLLRRL +S DE + LK+ Q++R DLE+ARLL EL RKREK+KRE + + L P L++ L+++LQ D +IFA PV P+Y I+ PMDF+ ++K+ + Y N+ DF+L++ NC +YNA++TI+Y A +LR + + R+ + IGFD+ETG+ Sbjct: 31 LTYAQAQRMVEIEIEGRLHRISIFDPLEIVSEDDLTAQEINECNSN---KENSEQPPQVCLRS-------KRHKASKEKKKSEVLPTAHGHTTTSVLPEPKVR---------VIECSPP-------------SAPNRSPSYYKFQDKSPEELDKEVEYDMDEEDYAWLEIINE---------------KRKSEGF--SAVSQDIFEFLMDRFEKESYCENQKQGDQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRNIPIDCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKEVAGSITTFSVKKTAYCDAHTPPGCVRRPLNIYEEPESKNGICR---KSSDKNIRST--SKARRKTTKAKKELNETCNVLPTITVPDIPPQRVNKIINQVSIPRKKQFIERVHSYWMLKRLSRNGIPLLRRLQSSLQSQRNIQESEDDEEVQALKKKLKYLQRLRHDLERARLLIELIRKREKLKREQVKVEQVAMELKLTPLTVLLRSLLEQLQEKDPARIFAHPVNLTEVPDYLDHIKHPMDFSTMKKRLEDQRYRNLNEFEEDFNLIIENCMKYNAKDTIFYRAAVRLRDHGGVLLRQARREANVIGFDEETGM 680 HSP 2 Score: 111.694 bits (278), Expect = 4.651e-24 Identity = 64/165 (38.79%), Postives = 89/165 (53.94%), Query Frame = 3 Query: 3033 HESQDVDDEDSTQDNSNNIFDSFDASEEDETE-GIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 H +D + S +N N + A+E +T + + ++ LEPL +VWAKC GYP +P LI+DP M G N V IP PP +V + G + + + FLVLFFD KR+WQWL + K+ P V E ID+ + S K+V AY A+ HL V E Sbjct: 987 HTIEDRSELISCIENGNYARAARIAAEVGQTNMWVAASTSAFLEPLKVVWAKCSGYPSYPALIIDPKMPRVGCHHNGVAIPVPPMDVLKTGDQMQTRAEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRVAYDRALNHLSRVQGE 1151
BLAST of Peregrin vs. Ensembl Mouse
Match: Brpf1 (bromodomain and PHD finger containing, 1 [Source:MGI Symbol;Acc:MGI:1926033]) HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0 Identity = 324/826 (39.23%), Postives = 462/826 (55.93%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ ++ ++ EDA Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDA 764 HSP 2 Score: 122.865 bits (307), Expect = 1.179e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1116 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1238
BLAST of Peregrin vs. Ensembl Mouse
Match: Brpf1 (bromodomain and PHD finger containing, 1 [Source:MGI Symbol;Acc:MGI:1926033]) HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0 Identity = 324/826 (39.23%), Postives = 462/826 (55.93%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ ++ ++ EDA Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDA 764 HSP 2 Score: 122.865 bits (307), Expect = 1.253e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 987 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1109
BLAST of Peregrin vs. Ensembl Mouse
Match: Brpf1 (bromodomain and PHD finger containing, 1 [Source:MGI Symbol;Acc:MGI:1926033]) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 321/808 (39.73%), Postives = 455/808 (56.31%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGM 746 HSP 2 Score: 122.865 bits (307), Expect = 1.188e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1115 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1237
BLAST of Peregrin vs. Ensembl Mouse
Match: Brpf1 (bromodomain and PHD finger containing, 1 [Source:MGI Symbol;Acc:MGI:1926033]) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 321/808 (39.73%), Postives = 455/808 (56.31%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGM 746 HSP 2 Score: 122.865 bits (307), Expect = 1.153e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1081 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1203
BLAST of Peregrin vs. Ensembl Mouse
Match: Brpf1 (bromodomain and PHD finger containing, 1 [Source:MGI Symbol;Acc:MGI:1926033]) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 324/832 (38.94%), Postives = 462/832 (55.53%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDA------MAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ ++ ++ EDA Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDA 770 HSP 2 Score: 123.25 bits (308), Expect = 1.101e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1088 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1210
BLAST of Peregrin vs. UniProt/SwissProt
Match: sp|B2RRD7|BRPF1_MOUSE (Peregrin OS=Mus musculus OX=10090 GN=Brpf1 PE=1 SV=1) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 321/808 (39.73%), Postives = 455/808 (56.31%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITI-HKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +D DV F +R KPP+ CP + C K+++S+S I HL H + + + + N QS +E + + P + +SYA +++ V + R R ISI ++L+ + E + SN + ++ K S KN +K + N ++ K E+ +E E+ TP + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL D+ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ Sbjct: 3 VDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVS--QSPGRE----------VMSYAQAQRMVEVDLHGRVHR--------ISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPK--------SGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQ--DTP---------------DAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGM 746 HSP 2 Score: 122.865 bits (307), Expect = 8.064e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1081 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1203
BLAST of Peregrin vs. UniProt/SwissProt
Match: sp|P55201|BRPF1_HUMAN (Peregrin OS=Homo sapiens OX=9606 GN=BRPF1 PE=1 SV=2) HSP 1 Score: 556.214 bits (1432), Expect = 7.891e-176 Identity = 290/653 (44.41%), Postives = 395/653 (60.49%), Query Frame = 3 Query: 699 NEESKEILSNPEDKTKEMKNKEQEK-----------VLQTPIPIFIEDI--NLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYKAGVSRGMYAN---------------SDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX---XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDA 2552 N +KE P K K+K +EK V + P E + LE + P Y +Y+EK+AEELDE VEYD+DEED IWL NE RR + P + Q EY++DR EKE +FES + + +DEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G + ++ S E++ K K + K+K RK+L ++R +S P IPP +L +IT+ + ++ K +FM R+H+YW +KR+ R+GVPLLRRL ++ + + LK WQ++R DLE+ARLL EL RKREK+KRE + + L P + L++ +++LQ DTG IF+EPV + P+Y I+ PMDF +++ ++ Y+N + DF+L++SNC +YNA++TI+Y A +LR + V + RQ +++G D ETG+ S+ EDA Sbjct: 132 NGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNE---------------RRKTEGVSP--IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAK-AKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 765 HSP 2 Score: 123.25 bits (308), Expect = 7.168e-27 Identity = 61/123 (49.59%), Postives = 76/123 (61.79%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRL---HSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 L+ LDLVWAKCRGYP +P LI+DP M G+ + VPIP PP V +LG + +H +LVLFFD KRTWQWL R KL P V +D+D+ + KS KSV AY A++H V E Sbjct: 1083 LDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGE 1205
BLAST of Peregrin vs. UniProt/SwissProt
Match: sp|G5E8P1|BRD1_MOUSE (Bromodomain-containing protein 1 OS=Mus musculus OX=10090 GN=Brd1 PE=1 SV=1) HSP 1 Score: 526.939 bits (1356), Expect = 1.683e-166 Identity = 289/706 (40.93%), Postives = 409/706 (57.93%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG---IRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPG--KRQKKLKDVRKLLNKRRNYTA-------------PISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX-XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 L+YA +++ V ++ + R R ++ P+ I +++DL ++E N+N ENS + ++ KR KN +++K NE P + L P +E Y P Y K++EK+AEELD VEYD+DEED WL NE R+ C S V Q E+++DRFEKE + E+ + IDEDAVC +C+DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL S + P DC LCPNKGGAFK+T+D+RW HVVC LWIPE+ FAN +F+EPI+ V I ARW+L CYLCKQK VGACIQCHK+NCYTAFHVTCAQ+AGLYMK+E ++++G + +RK+A+CDVH+P G R + D E+ K G +++ +K VR R+ + P IPP++L I + + ++ K++F+ R H+YW +KR R+G PLLRRL +S DE LK+WQ++R DLE+ARLL EL RKREK+KRE + + L P L++ ++++LQ D KIFA+PV+ P+Y I+ PMDF +RK+ ++ Y N+ DF+L++ NC +YNA++T++Y A +LR + V + R+ + IG ++ +G+ Sbjct: 31 LTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSN---KENSERPP----------VCLRTKRH---KN-NRVKKKNEVLPSTHGTPASAS----------ALPEPKVRIVE-----YSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIINE--------------KRKGD---CVSAVSQNMFEFLMDRFEKESYCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGSATFSVRKTAYCDVHTPPGC---TRRPLNIYGDVEM---KNGVCRKESSVKTVRSTSKVRKKAKKAKKTLAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTPLTVLLRSVLEQLQEKDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVESIGLEEASGM 681 HSP 2 Score: 108.612 bits (270), Expect = 2.065e-22 Identity = 68/186 (36.56%), Postives = 93/186 (50.00%), Query Frame = 3 Query: 2970 EETKLNSSISFNDYTKNPEIAHESQDVDDEDSTQDNSNNIFDSFDASEEDETEGIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 + ++L S I +Y K IA E +N++ S DA+ LEPL +VWAKC GYP +P LI+DP M N V IP PP +V ++G + S + FLVLFFD KR+WQWL + K+ P V E ID+ + S K+V A+ A+ HL V+ EP Sbjct: 888 DRSELISCIENGNYAKAARIAAEV-----------GQSNMWISTDAAASV------------LEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEP 1050
BLAST of Peregrin vs. UniProt/SwissProt
Match: sp|O95696|BRD1_HUMAN (Bromodomain-containing protein 1 OS=Homo sapiens OX=9606 GN=BRD1 PE=1 SV=1) HSP 1 Score: 523.087 bits (1346), Expect = 4.205e-165 Identity = 290/704 (41.19%), Postives = 408/704 (57.95%), Query Frame = 3 Query: 438 LSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPA---GIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTA-------------PISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-DEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 L+YA +++ V ++ + R R ++ P+ I +++DL ++E N+N ENS + ++ KR KN +++K NE P + L P +E Y P Y K++EK+AEELD VEYD+DEED WL NE R+ C V Q+ E+++DRFEKE H E+ + IDEDAVC +C+DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL S + P DC LCPNKGGAFK+T+D+RW HVVC LWIPE+ FAN +F+EPI+ V I ARW+L CYLCKQK VGACIQCHK+NCYTAFHVTCAQ+AGLYMK+E ++++G +RK+A+CDVH+P G R + D E+ + +++ +K VR R+ + P IPP++L I + + ++ K++F+ R H+YW +KR R+G PLLRRL +S + DE LK+WQ++R DLE+ARLL EL RKREK+KRE + + L P L++ ++D+LQ D +IFA+PV+ P+Y I+ PMDF +RK+ ++ Y N+ DFDL++ NC +YNAR+T++Y A +LR + V + R+ D IG ++ +G+ Sbjct: 31 LTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNK---ENSERPP----------VCLRTKRH---KN-NRVKKKNEALPSAHGTPASAS----------ALPEPKVRIVE-----YSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNE--------------KRKGD---CVPAVSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGC---TRRPLNIYGDVEMKNGV-CRKESSVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGM 681 HSP 2 Score: 107.457 bits (267), Expect = 4.186e-22 Identity = 55/124 (44.35%), Postives = 74/124 (59.68%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LEPL +VWAKC GYP +P LI+DP M N V IP PP +V ++G + S++ FLVLFFD KR+WQWL + K+ P + E ID+ + S K+V A+ A+ HL V+ EP Sbjct: 927 LEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEP 1050
BLAST of Peregrin vs. UniProt/SwissProt
Match: sp|B2KF05|BRPF3_MOUSE (Bromodomain and PHD finger-containing protein 3 OS=Mus musculus OX=10090 GN=Brpf3 PE=1 SV=1) HSP 1 Score: 511.531 bits (1316), Expect = 4.268e-159 Identity = 269/597 (45.06%), Postives = 355/597 (59.46%), Query Frame = 3 Query: 828 EKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKIS--GPA-GIRKSAFCDVHSPS----GYKAGVSRGMYANSDEELTS-----------------------------EKPGK---RQKKLKDVRKLLNKRRNYTAP-ISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXX-XXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETG 2495 + E P Y +Y+EK E+LD VEYD+DEED+ WL NE RRA S V T E ++DR EKE + ES + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL SPS PVDC LCPNKGGAFKQT+D WAHVVC +WIPE+ FAN +FLEPIE ++ I ARW+L CY+CKQK +GA IQCHK NCYTAFHVTCAQ+AGL+MKIE + S G +RK+A+C+ HSPS K R + DE+ K GK +QK K+ + + + T P ++ P IP +L +I + + K +FM R+H YW +KR+ R+GVPL+RRL + DE +S + LK+WQ++R DLE+ARLL EL RKREK+KRE + + + L P L++ +D LQ D+ IFAEPV+ + P+Y + I PMDF+ +R+K +S+ Y +E DF+L+++NC +YNA++TI++ A +LR + RQ + IG+D E G Sbjct: 127 QPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDIAWLDMVNE--------------KRRADGH---SSVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTTFTVRKTAYCEAHSPSVAVARRKGDSPRSLSEVGDEDGPKEGGGEEEQEEAEEEGQEGQGGVGSPLKGVSKKGKMSLKQKIKKEPEEAGREAPSITLPMVTVPQIPSYRLNKICSGLSFQRKTQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQEKDSAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERG 706 HSP 2 Score: 124.02 bits (310), Expect = 3.792e-27 Identity = 60/120 (50.00%), Postives = 78/120 (65.00%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 LEPL+LVWAKCRGYP +P LI+DP M G+ N VPIP PP +V +LG + + + FLVLFFD KRTWQWL R+K+ P V++ +D+ + K+ KSV AY A+ HL V Sbjct: 1073 LEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRV 1192
BLAST of Peregrin vs. TrEMBL
Match: A0A5K4F181 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 653.284 bits (1684), Expect = 0.000e+0 Identity = 359/826 (43.46%), Postives = 506/826 (61.26%), Query Frame = 3 Query: 132 IMDDIDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDN--ESAYLKIPN-----MKHTSKFVIDTIQLSYADSKKFVILQ----NDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIR--KLNEESKEILSNPEDKTKEMKN-KEQEKVLQTPIPIFIEDINLEYFEKETPHDVEG--YVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESIT-------------GSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNID--VRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-----DEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF 2501 + +D D+D+FL+RI+GNKPPF CP + C K+ RS++ + KH++ +H+ I+I V + + + C + N + E A + + + +H SK +++ D+ V+ + +FRCN+ VP+ I ++++N + T+T + S+SE K+ R + KN +I+ K + S + S+ K N E V++ P ++ I+ E+ +++ H EG Y++++EKT++ELDE+VEYDLDEEDL WL + N +R S P V ++T+E+++DRFEK+ F T G N H+ IDEDAVC VC DGTC+N+NVILFCDVCNLAVHQECYGVPYVPEG WLCRKCLHSPS PV C LCPN+GGAFK+T D+RWAHV+CGLW+PE+MFANL FLEP+E +++I AARWRL C++CKQ+NVGACIQCHKS+CY AFHVTCAQ AGLYMKIE ++ G GIRKSAFCD H P + + ++GMYA+SD + + L+ RK+L +RRN + P++ K+ I + +K EF+ + +A+WK+KRE+R GVPLL+RL A S + A ++ D S +M ++LKFWQQ+RQDLE+ RLLSEL RKRE+IKR++FR F++ D + P + ID+LQ LDT + FAEPV ++AP+YS II+ PMDF+ +RKK ++ EY I L DF+LM+ NC YN +IYY A KLR S P+ +I F +TGL Sbjct: 2 VYHPVDFDIDDFLSRIQGNKPPFVCPSETCQKVCRSYNYMQKHML-LHRPPAPIDIPGPLVNGEVSSNFKCASALENGSDQIEKAPIVVGHPTENLCRHQSK-----TPMTFTDAHTSVVFEASPATKGHTFRCNICVPLTICF-QNMSNKVDHDSCTST------QELSKSEGIPINKKQPSSRSKMPHHKNKGRIKNNKSGQISDKQQSDLGGKGSLYTNGTEVNNVIEIPKAVY--SIDPEFSIRKSIHLKEGSSYIRFIEKTSDELDEVVEYDLDEEDLFWLKRINA---------------KRNSLSLPP--VSESTLEWIMDRFEKKARFRLFTSNGCETTDVLPDIGGN-HSGIDEDAVCAVCQDGTCENTNVILFCDVCNLAVHQECYGVPYVPEGPWLCRKCLHSPSEPVSCVLCPNRGGAFKKTTDDRWAHVICGLWVPEVMFANLTFLEPLEGIDRIAAARWRLQCFICKQRNVGACIQCHKSSCYRAFHVTCAQHAGLYMKIEHTDD-PGDLGIRKSAFCDQHCPPDHFSSSNKGMYAHSDSDGPQSPERAARIHLRKARKILAERRNSKPSVCVPIVSKAKIDLILSKLSGVSGDKMEFLKQTYAFWKLKREFRRGVPLLKRLQACSLHRSAANFAVAATTGDAESHQMRAHLKFWQQLRQDLERGRLLSELIRKRERIKRDIFRLFVTEIDFKIKPLVVFQLRFIDQLQALDTNQFFAEPVEPSLAPDYSLIIKKPMDFSTMRKKIENFEYCTINELLSDFNLMLENCFEYNRETSIYYTAAMKLRERSKPIISEALTIAKQINFCPKTGLL 793 HSP 2 Score: 128.257 bits (321), Expect = 7.005e-26 Identity = 61/131 (46.56%), Postives = 84/131 (64.12%), Query Frame = 3 Query: 3153 RLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG-RLHSNQHK-----FLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPY 3527 + PLD+VWAKC G PW+P +IVDP ++ G N VPIP PPE+V + G R+ N+ LVLFFD KRTWQWL +KL+P + +++D L+ KS+ SV +AY+ A+ H+C V+ PYPY Sbjct: 1304 QFSPLDIVWAKCLGSPWYPAIIVDP-DANEGYSHNGVPIPLPPESVLKWGKRIAFNKSTDDSELLLVLFFDTKRTWQWLSPQKLQPLGINKELDYERLREGRKSKMKHSVTKAYRRAVEHICKVHGRPYPY 1433
BLAST of Peregrin vs. TrEMBL
Match: A0A4Z2DLA2 (Peregrin OS=Schistosoma japonicum OX=6182 GN=EWB00_011311 PE=4 SV=1) HSP 1 Score: 652.129 bits (1681), Expect = 0.000e+0 Identity = 355/829 (42.82%), Postives = 503/829 (60.68%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDC-NNVQSNKDNESAYLKIPNMKHTSKFVIDTIQ------LSYADSKKFVILQ----NDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFS----LKNYKKIRKLNEESKEILSNPEDKTK-------EMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEG--YVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNL------------HNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNID--VRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-----DEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF 2501 +D D+D+FL+RI+GNKPPF CP + C K+ RS++ + KH++ +H+ I+I V + + + C +++++ D S L + +TSK D Q + + D+ V+ + +FRCN+ VP+ + L NT N + D+ T + S + I I +K++F L + K R N ++ ++ + DK K E IP + I+ E+ +++ EG Y++++EKTA+ELDE+VEYDLDEEDL WL + N +R S P V ++T+E+++DRFEK+ F + S H+ IDEDAVC VC DGTC+N+NVILFCDVCNLAVHQECYGVPYVPEG WLCRKCLHSPS PV C LCPN+GGAFK+T D+RWAHV+CGLW+PE+MFANL FLEP+E +++I ARWRL C++CKQ+NVGACIQCHKS+CY AFHVTCAQ AGLYMKIE ++ G +GIRKSAFCD H P + + ++GMYA+SD + + L+ RK+L +RRN + P++ K+ I + +K EF+ + +A+WK+KRE+R GVPLL+RL A S + A ++ D S +M + LKFWQQ+RQDLE+ RLLSEL RKRE+IKR++FR+F+ + + P + ID+LQ LDT + FA+PV ++AP+Y+ II+ PMDF+ IRKK ++ +YI ++ + DF+LM+ NC YN +IYY A KLR S P+ +I F +TGL Sbjct: 38 VDFDIDDFLSRIQGNKPPFVCPSETCQKVCRSYNYMQKHML-LHRPPTPIDIPGPLVNGNISAGLKCISSLKNASDQTSKELIL--FSNTSK---DFYQQQNRNSMVFTDAHSSVVFEASPATKGHTFRCNIYVPLTVR----LQNTP------NQIEDDPLIST---QTLSKPESISINKKQTFGRSKILHHKNKGRIKNNKNGLVMGHSSDKQKYESCDKGSFHTSGVEVNSAVEIPKAVYSIDPEFSIRKSIRLKEGSSYIRFIEKTADELDEVVEYDLDEEDLFWLERINA---------------KRKSLSLLP--VTESTLEWIMDRFEKKARFRMSSSSGYETTDVYPDIGGNHSGIDEDAVCAVCQDGTCENTNVILFCDVCNLAVHQECYGVPYVPEGPWLCRKCLHSPSEPVSCVLCPNRGGAFKKTTDDRWAHVICGLWVPEVMFANLTFLEPLEGIDRIAPARWRLQCFICKQRNVGACIQCHKSSCYRAFHVTCAQHAGLYMKIEHTDD-PGDSGIRKSAFCDQHCPPDHFSSSNKGMYAHSDSDGPQSPERAARIHLRKARKILAERRNSKPSVCVPIVSKAKMNLILSKLSGVSGDKMEFLKQTYAFWKLKREFRRGVPLLKRLQACSLHRSAANFAVAATTGDAESHQMRAQLKFWQQLRQDLERGRLLSELIRKRERIKRDIFRSFVKETELKIKPFVVFQLRFIDKLQALDTNQFFAKPVEPSLAPDYALIIKNPMDFSTIRKKIENFDYITMDDMLSDFNLMLENCFEYNRETSIYYTAAVKLRERSRPIISEALALMKQINFCPKTGLL 829 HSP 2 Score: 129.798 bits (325), Expect = 2.137e-26 Identity = 62/131 (47.33%), Postives = 84/131 (64.12%), Query Frame = 3 Query: 3153 RLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG-RLHSNQHK-----FLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPY 3527 +L PLD VWAKC G PW+P +IVDP +S G N VPIP PPE+V + G R+ N+ LVLFFD KRTWQWL +KL+P + +++D L+ +S+ SV +AY+ A+ H+C V+ PYPY Sbjct: 1348 QLSPLDTVWAKCLGSPWYPAIIVDP-DASEGYSHNGVPIPQPPESVLKWGKRIVCNKSTDDLELLLVLFFDTKRTWQWLSPQKLQPLGMNKELDCEKLREGRRSKMKHSVTKAYRRAVEHICKVHGRPYPY 1477
BLAST of Peregrin vs. TrEMBL
Match: A0A5K3FIJ2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 635.95 bits (1639), Expect = 0.000e+0 Identity = 349/804 (43.41%), Postives = 494/804 (61.44%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDK---RSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETP-HDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFES-------ITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH-SPSGYKAGVSRGMYANSDEELTSEKPGK---RQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDV--RNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-----DEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVF-ERYERQYDEIGFDK 2486 +D D+ EFL RI GNKPP+ CP DGC + F+SF AI +H+ H+ + DI + + + SA+ + ++ SKF + + DS+K V+ S RC+++VP++ S D NS+D +L + + + ++R ++ + + + +S +S ++ ++N ++ + PIP F D N K P D Y++++E++ +ELDEIVEYDLDEEDL WL K N R S P ++Q+T+E+V+DRFEKE F + +T S + ID+DAVC VC DGTC+N+NVILFCDVCNLAVHQECYGVPYVPEG WLCRKCLHSPS P+ CCLCPN GGAFK+T+D+RWAHV+CGLW+PE+MFANL FLEP+E+++KI ARWRL C++CKQ+NVGACIQCHK +CY AFHVTCAQQAGLYMKIEQS+ S GIRK+AFCD+H PS +KA +GMYA+SDEE S+ + ++ K+++ RK+L +RRN + P++P K I + R EF R++A+WK+KRE R GVPLL+RL ASS +A L+ DE + +M S L FWQ++RQDLE+ARLLSEL+RKRE++KRE+ R ++ + L PT + DLI +LQ+ D FA PV+ +AP+Y +I+ PMDF +++K ++Y+ + + DF L+++NC YN +T YY A L + +F E YE ++ ++ FD+ Sbjct: 6 VDFDIYEFLTRIHGNKPPYRCPADGCRRTFKSFKAIQQHM-ECHRAPDPV-------------DIPATFISAPEHTSSAHSR--SLYRNSKFP----SMLFPDSQKCVVFNLTGVGISSVRCSIHVPLHFSFDFS-----------------NSDD----QLLNKLEPVALRRMKNIKSR-VSQPALMPIDSCNSISQSSNECSAVENHDRSSA-KVPIPQFEIDQNFICQRKPAPWKDGCAYMRFIERSFDELDEIVEYDLDEEDLFWLEKINA---------------DRMSKMMEP--IEQSTLEWVLDRFEKEARFRTTTENGAGLTTSVMMAGIDDDAVCAVCQDGTCENTNVILFCDVCNLAVHQECYGVPYVPEGPWLCRKCLHSPSEPISCCLCPNIGGAFKKTSDDRWAHVICGLWVPEVMFANLTFLEPLEDIDKIAPARWRLQCFICKQRNVGACIQCHKPSCYRAFHVTCAQQAGLYMKIEQSDDPSD-LGIRKNAFCDLHCPPSHFKANAHKGMYAHSDEEGASKDADEETVKRTKIRNARKVLAERRNSKPLVCVPMVPKSKTDLIFSELTGVKRGSVEFFQRVYAFWKLKREVRCGVPLLKRLQASSVNRGVASLAAAAAAGDEEAQKMRSQLIFWQRLRQDLERARLLSELTRKRERVKREILRTTLAQLECRLRPTFRALTDLITQLQSKDVRNFFANPVSTDVAPDYCTVIKQPMDFETMKRKCADHQYLCVADVFNDFSLIVNNCCTYNGSDTTYYKAAVSLSDQCASIFKEAYENEHFDL-FDE 747 HSP 2 Score: 130.954 bits (328), Expect = 9.738e-27 Identity = 75/217 (34.56%), Postives = 102/217 (47.00%), Query Frame = 3 Query: 3036 ESQDVDDEDSTQDNSNNIFDS---FDASEEDETEGIKSQSNIR-------LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR------------------------------------LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPYDQFHFDE 3548 + +++ +E Q + D+ +++E +G +QS ++ EPLDLVWAKCRG PW+P LI+DP S+ N VPIP PPE+V +G ++ FLVLFFD KRTWQWL REKL P A ID L +S+ +SV +AY AI H C V+ PYP+ DE Sbjct: 1049 QQKEISEERGQQRPNTGTVDTNRPLGSTKEGPQKGQSAQSGVKPGHGEGNFEPLDLVWAKCRGSPWYPALIIDPTASTEDYNHNGVPIPTPPESVLNVGSGAPSSFVNALRGPGSLSPSSVTCSSPAPVAAPNSPPVNQQPPTFLVLFFDGKRTWQWLPREKLLPLATNTAIDDEKLHEAKRSKLKQSVVKAYGRAIEHYCKVHGRPYPFTDSCSDE 1265
BLAST of Peregrin vs. TrEMBL
Match: A0A158QDI9 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS3109 PE=4 SV=1) HSP 1 Score: 630.558 bits (1625), Expect = 0.000e+0 Identity = 355/804 (44.15%), Postives = 499/804 (62.06%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGC-SKLFRSFSAISKHLITIHKKSKEIEIC-EIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQ---NDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEG-YVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSN---------LHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH-SPSGYKAGVSRGMYANSDEELTSEKPGK---RQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNID--VRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSS---------EMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVF-ERYERQ 2462 +D D+ EFL RIRGNKPPFTCP + C K F++F AI +H+ H+ ++I I V +EN ++ ++ N ++ + + DS+K V+ ++ +S RC++NV I+++ E L N LNT SND + SE+SS R R KN +I K+ E+ E+ T +K + + V+ P+P F D Y +++ P V+G Y++++E +AEEL+EIVEYDLDEEDLIWL K N+ ++ +T + Q+ +E+V+DRFEK+ F + TG N L+N +EDAVC VC DG C+N NVILFCDVCNLAVHQ+CYGVPY+PEG WLCRKCL SPS PV CCLCPN GGAFK+T+D+RWAHV+CGLWIPE+MFANL FLEP+++++KI RW L C++CKQKNVGACIQCHK NCY +FHVTCAQQAGLYMKIEQS+ +G+RK A+CD+H PS +KA RGMYANSD+++ E+P + ++ + R++L KRRN + P++ K+ +I R KEEF R++A+WK+KRE R GVPLL+RL A+S A LS ++ +M S L F Q++R DLE+ARLL EL RKRE++K+EL N + + + PT + + +LI +LQ DT + F EPVT +AP+Y +II+ PMDF+ ++KK +EY + +++ FDL++SNC YNA+ T+YY A L + P+F E +E++ Sbjct: 6 VDFDIPEFLNRIRGNKPPFTCPAEPCKQKPFKNFKAIQQHM-HFHRPPDPVDISNTIGVTFEENSKLE-------------VIEPSNSRYRP--------MRFLDSQKNVVFNLTGDNAQSVRCSINVLIHLT-SEPLPNDHQIPLNT-------SNDLNGSEVSS------AHRGRR---KNKHRISKVPEQPPV-----ENGTALVKQEPKLPVISIPVPKFEVDSCFAY-QRKPPTWVKGAYLRFIEHSAEELEEIVEYDLDEEDLIWLEKINDI-------------RKKQGFET----IKQSQLEWVLDRFEKKAVFRT-TGENGANVSTTMLLNNSEEEDAVCAVCQDGNCENLNVILFCDVCNLAVHQDCYGVPYIPEGSWLCRKCLISPSEPVSCCLCPNTGGAFKKTSDDRWAHVICGLWIPEVMFANLTFLEPLDDIDKISPQRWALRCFICKQKNVGACIQCHKQNCYKSFHVTCAQQAGLYMKIEQSDDPDD-SGVRKLAYCDMHCPPSHFKANAHRGMYANSDDDIAGEEPDEESIKRTTINKARRVLAKRRNSKPQVCVPIVTKSKMVDILSEFTGPARGKEEFFKRVYAFWKLKREARRGVPLLKRLQAASRLRGAASLSEAAAAALAASSEEQEKMRSQLIFTQRLRHDLERARLLCELVRKRERVKQELVLNSRAQLNMRIQPTFDFLGELIKKLQARDTRRFFCEPVTTDIAPDYLEIIKHPMDFSTMKKKLAEHEYFTVAQVKEHFDLIVSNCCEYNAKETVYYKAAVALADQCAPIFKEAFEKE 745 HSP 2 Score: 82.8037 bits (203), Expect = 4.941e-12 Identity = 53/147 (36.05%), Postives = 71/147 (48.30%), Query Frame = 3 Query: 3213 LIVDPFMSSNGICDNKVPIPDPPENV--RELGRLHS--NQH-------------------------------KFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPYDQFHFDE 3548 L++DP SS+ N VPIP PPE++ + G + S NQ FLV+FFD KRTWQ L REKL P A ID LQ +S+ +SV +AY+ A+ H C VN PYP+++ D+ Sbjct: 1084 LVIDPAASSDQYTQNGVPIPVPPESLLNGQSGEVGSPLNQRGGGLDAAPASPSSNGTSNSPIATTPPPVGGPTFLVVFFDGKRTWQRLPREKLFPLATNTVIDEEKLQEARRSKLRQSVVKAYQRAVEHYCKVNRRPYPFNENSADD 1230
BLAST of Peregrin vs. TrEMBL
Match: A0A3R7JZ53 (Peregrin OS=Clonorchis sinensis OX=79923 GN=BRPF1 PE=4 SV=1) HSP 1 Score: 629.787 bits (1623), Expect = 0.000e+0 Identity = 343/815 (42.09%), Postives = 494/815 (60.61%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEI--CEIDVINDENKDIDCNNVQSNKDN--ESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQND---KRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVE---GYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITG---SNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKL----KEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXI-----DEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYD 2522 +D D+D+FLAR +GNKPPF CP + C K+ +SF+ I KH++ IH+ I+I D++ + SN + + HT+ +S+ DS V + ++FRC++ VP+ + E + T + + T TV ++++N+TSQ L +N K R +KN + + + + N ++++ ++ L+ P P++ +++ E+ K+ V+ GY++++EKT +ELDE+VEYDLDEEDL WL + N N R VD+ T+E+ IDRFEKE F ++ L + IDEDAVC +C DG+C+N+NVILFCDVCNLAVHQECYGVPYVPEG WLCRKCLHSPS PV C LCPN GGAFK+T+D+RWAHV+CGLW+PE+MFANL FLEP+E +++I ARWRL C++CKQ+N GACIQCHK++CY AFHVTCAQQAGLYMKIE ++ AGIRK+AFCD+H P + ++GMYANS+ E T + +L+ RK L +RRN I P++P K+ + D+I + +F+ + +A+WK+KRE R GVPLL+RL A S + A ++ D + +M L+FWQQ+RQDLEKARLLSEL RKRE++KR++FR F + + + + L++ LQ LD FAEPV +AP+Y II+ PMDF +R K + + Y++I+ D++LM++NC +YN R +IYY A+++ + +F IG TGL A +D Sbjct: 6 VDFDIDDFLARTQGNKPPFICPAETCQKVHKSFAHIQKHML-IHRPPAPIDIPASPSDLVQSTTAPYGLSASPSNGYSLTHRGVRNSSSASHTNHLST----ISHTDSCAVVFGPSSITHGQTFRCSIYVPLTFRL-EPIRKTE-SAIKTETV-NQSTNNTSQ--LDNNGKSSNRSR-----VKNRNGLMRTRDTNGYTEENCISQSQQQQHTNGMTELRLPQPVY--EVDPEFVFKKPSLLVKEGHGYIRFIEKTLDELDEVVEYDLDEEDLFWLERIN---------------NERKLKGLM--AVDETTLEWTIDRFEKEAKFRQLSSDEDGPLTHSIDEDAVCSICQDGSCENTNVILFCDVCNLAVHQECYGVPYVPEGPWLCRKCLHSPSEPVSCVLCPNTGGAFKKTSDDRWAHVICGLWVPEVMFANLTFLEPLEGIDRIAPARWRLQCFICKQRNAGACIQCHKTSCYRAFHVTCAQQAGLYMKIEDTDD-PKEAGIRKNAFCDLHCPPDHFTKGNKGMYANSESENTHSPEQAARIQLRKARKALAERRNSKPSICVPIVPKAKIDLMCTMLADDIS-GDVMDFLGKAYAFWKLKREARRGVPLLKRLQACSIHRSAANFAMAATTGDGEAKQMRKQLQFWQQLRQDLEKARLLSELIRKRERVKRDIFRVFTTEAELQIKSINIFLLRLLEILQDLDKNGFFAEPVGPELAPDYHLIIKHPMDFATMRSKIEQSCYLSIKEFESDYNLMLNNCFQYNRRESIYYAAATRISEQGKQIFREAFAIAQRIGLSPHTGLLAVMEPHD 784 HSP 2 Score: 132.494 bits (332), Expect = 3.141e-27 Identity = 66/145 (45.52%), Postives = 90/145 (62.07%), Query Frame = 3 Query: 3120 ETEGIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSN---------QHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPY 3527 E + S S+ + PLD+VWAKCRG PW+P L++DP +S+G N VP+P PPE+V GR ++ + LVLFFD KRTWQWL R KL+P + D+DR L+ +S+ SV +AY+ A+ HLC V+ PYPY Sbjct: 1232 ELGAVDSLSDRHIGPLDVVWAKCRGSPWYPALVIDP-GASDGYSHNGVPVPIPPESVLRWGRRITDGSNAVADEEKPNLLVLFFDTKRTWQWLSRYKLQPLGLCVDVDRERLRESRRSKMKNSVIKAYRRAVEHLCKVHGRPYPY 1375
BLAST of Peregrin vs. Ensembl Cavefish
Match: brpf1 (bromodomain and PHD finger containing, 1 [Source:ZFIN;Acc:ZDB-GENE-040426-731]) HSP 1 Score: 567 bits (1460), Expect = 0.000e+0 Identity = 317/813 (38.99%), Postives = 444/813 (54.61%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK---AGVSRGMYANS---------------------DEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +D DV F +R KPP+ CP + C K+++S+S I HL + +N + Q + + + + ++YA +++ V L+ + R ISI EDL+ V +E+S+ ++ K G K KK + ++ P ++ P +F E L+ + P Y +Y++K+ EELDE VEYD+DEED IWL N+ RR T + Q EY++DR EKE +FES + ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G GV ++S E K ++K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+HAYW +KR+ R+GVPLLRR + + +S +E + + LK WQ++R DLE+ARLL EL RKREKIKRE + + + L P + L++ +++LQ DT F EPV P+Y IQ PMDF + +S+ Y++ E DF L+++NC +YNA++T++Y A +LR + + RQ + IG++ ETG+ Sbjct: 3 LDFDVKTFCHNLRATKPPYECPIETCRKVYKSYSGIEYHLYHY---------------DHDNPPPIQSTPQKKRKGRPPRVSLSGSHSEHSHSPERETMTYAQAQRMVELEIGGKVHR--------ISIFEDLD----------VVSEEDSDAEDAPASANGGKGTGATPKSGKHKSKEKKKEGSHHHGN--MAGP--------------AVKLPEAVFRE---LDQERPDAPPRTLSYYRYIDKSVEELDEEVEYDIDEEDYIWLDIMND--------------KRRIDGVT---PIPQEVFEYLMDRLEKESYFESHNKGDPNSLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASTSHSEGEAEDEEEVSAVGEEEGKGWSSERAKRAKAKSRRKMKRARKILAERRAAAPVVSVPCIPPHRLSKITANLTVPRKSQFMQRLHAYWTLKRQSRNGVPLLRR-LQTHLQSQRNPEDTEEKHAALKEQLKAWQRLRHDLERARLLVELIRKREKIKREAIKVQQLVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLNEVPDYLDHIQQPMDFQTMWLSLESHHYLSFEAFEGDFLLIVNNCLKYNAKDTVFYRAALRLREAGGAILRQARRQAERIGYEYETGM 744 HSP 2 Score: 120.168 bits (300), Expect = 7.021e-27 Identity = 65/163 (39.88%), Postives = 89/163 (54.60%), Query Frame = 3 Query: 3030 AHESQDVDDEDSTQDNSNNIFDSFDASEEDETEG-----IKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRH 3494 A + ++ T+++S ++ S S + G + S L+ LDLVWAKCRGYP +P LI+DP M G+ VPIP PP V +LG + +H FLVLFFD KRTW WL R KL P V +++D+ + KS KSV AY A++H Sbjct: 1004 AFQEDSSEETSGTENDSYSVGGSRGVSHLVRSRGRSSCWMSSTDYSSLDALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPLEVLKLGEQMTQEAREHLFLVLFFDNKRTWLWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQH 1166
BLAST of Peregrin vs. Ensembl Cavefish
Match: brpf3a (bromodomain and PHD finger-containing protein 3-like [Source:NCBI gene;Acc:103021900]) HSP 1 Score: 517.694 bits (1332), Expect = 1.272e-167 Identity = 289/731 (39.53%), Postives = 405/731 (55.40%), Query Frame = 3 Query: 417 FVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEK-ETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPS--------GYKAG--------VSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISF-PVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF-------ANKSIYD 2522 F + L+YA S+K V ++ + R R N+ P+ + +++L + E N+N + E N R R + K R+ K+ KN P P F + L+ F E P Y +YVEKT+EEL+ EYD+DEED+ WL N+ +R S + V T E +IDR E+E ES + + N IDEDA C VC+D C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEPIE V+ I ARW+L CYLCKQ+ GA IQCHK+NCY AFHVTCAQ+AGL+MKI+ + +G G ++K+AFC HSP+ G+ G + G A ++ + P Q+K K + R P+ P IP +L +I + V+ K +FM R+H YW +KR R+GVPL+RRL D + LK+WQ++RQDLEKARLL EL RKRE++KRE + + L P + L++ +++LQ DT +IF P P+Y + + PMDF+ +R+K ++++Y ++ L DF+LM+SNC +YN+ +T+++ A++L+ + +RQ +G D +TG+ A+KS +D Sbjct: 28 FSVTRETLTYAQSQKMVEVELEGRIHRINIFDPLAVVTEDELLAQEVQECNSNKENSEQEN-----------------RGRHVHHTSTNKARR----------------KDGKNGP------LPKPTFRK---LDAFTPNEAPPLPVAYYRYVEKTSEELETEAEYDMDEEDMAWLEMVNQ---------------KRVSDGH--ASVQPDTFELLIDRLERESILESRSQALSQNTIDEDAFCCVCMDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPIEGVKNIPPARWKLTCYLCKQRGRGASIQCHKANCYRAFHVTCAQRAGLFMKIDPVRE-TGTNGTTFTVKKTAFCGSHSPATAEGDEDGGFAGGRNNRGQRAYTLGPAAQQNQRGNKKAPPTPQQK-KTRKSADGVSRKTGVPLLLVPQIPSYRLNKICTGVSVQRKNQFMQRLHNYWLLKRHSRNGVPLIRRLHTHLQTQKTEQREPDARLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQVSLELQLTPALVLLRSTLEQLQEKDTAQIFTSPTFFLHVPDYLEFVSDPMDFSTMREKLEAHKYCSVLDLEADFNLMVSNCLKYNSTDTVFHKAATQLKEVGGAILRNAQRQAVSVGLDPKTGMHLPDSKPNASKSCWD 697
BLAST of Peregrin vs. Ensembl Cavefish
Match: brpf3a (bromodomain and PHD finger-containing protein 3-like [Source:NCBI gene;Acc:103021900]) HSP 1 Score: 527.709 bits (1358), Expect = 4.731e-166 Identity = 292/739 (39.51%), Postives = 414/739 (56.02%), Query Frame = 3 Query: 417 FVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSN------DTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFE-KETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPS--------GYKAG--------VSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISF-PVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLF-------ANKSIYDLV 2528 F + L+YA S+K V ++ + R R N+ P+ + +++L + E N+N + E N TS ++ + G R R F + + + ++ + PE P P F + L+ F E P Y +YVEKT+EEL+ EYD+DEED+ WL N+ +R S + V T E +IDR E+E ES + + N IDEDA C VC+D C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEPIE V+ I ARW+L CYLCKQ+ GA IQCHK+NCY AFHVTCAQ+AGL+MKI+ + +G G ++K+AFC HSP+ G+ G + G A ++ + P Q+K K + R P+ P IP +L +I + V+ K +FM R+H YW +KR R+GVPL+RRL D + LK+WQ++RQDLEKARLL EL RKRE++KRE + + L P + L++ +++LQ DT +IF PV P+Y + + PMDF+ +R+K ++++Y ++ L DF+LM+SNC +YN+ +T+++ A++L+ + +RQ +G D +TG+ A+KS +D V Sbjct: 46 FSVTRETLTYAQSQKMVEVELEGRIHRINIFDPLAVVTEDELLAQEVQECNSNKENSEQENRGRHVHHTSTNKARRKDGKNGGGRARRFGSQQF-------SQHQDHQTQPEGPL--------------PKPTFRK---LDAFTPNEAPPLPVAYYRYVEKTSEELETEAEYDMDEEDMAWLEMVNQ---------------KRVSDGH--ASVQPDTFELLIDRLERESILESRSQALSQNTIDEDAFCCVCMDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPIEGVKNIPPARWKLTCYLCKQRGRGASIQCHKANCYRAFHVTCAQRAGLFMKIDPVRE-TGTNGTTFTVKKTAFCGSHSPATAEGDEDGGFAGGRNNRGQRAYTLGPAAQQNQRGNKKAPPTPQQK-KTRKSADGVSRKTGVPLLLVPQIPSYRLNKICTGVSVQRKNQFMQRLHNYWLLKRHSRNGVPLIRRLHTHLQTQKTEQREPDARLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQVSLELQLTPALVLLRSTLEQLQEKDTAQIFTSPVNLKEVPDYLEFVSDPMDFSTMREKLEAHKYCSVLDLEADFNLMVSNCLKYNSTDTVFHKAATQLKEVGGAILRNAQRQAVSVGLDPKTGMHLPDSKPNASKSCWDEV 741 HSP 2 Score: 117.087 bits (292), Expect = 6.363e-26 Identity = 63/135 (46.67%), Postives = 80/135 (59.26%), Query Frame = 3 Query: 3108 SEEDETEGIKSQSNIR--LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHK---FLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHL 3497 S E++ +KS S LEPL LVWAKCRGYP +P + VDP M G+ N +PIP PP+ V LG + + FLVLFFD KRTWQWL +KL P V + +D+ L K KSV+ AY+ A+ HL Sbjct: 1060 SSNPESDSVKSSSQQSEDLEPLSLVWAKCRGYPSYPAMTVDPEMPKEGVLHNGIPIPVPPKEVLRLGERRRRETEDKLFLVLFFDTKRTWQWLPLDKLHPMGVDDTVDKLRLMEGKKRNVRKSVNTAYERAMNHL 1194
BLAST of Peregrin vs. Ensembl Cavefish
Match: brpf3b (bromodomain and PHD finger containing, 3b [Source:ZFIN;Acc:ZDB-GENE-081104-468]) HSP 1 Score: 509.99 bits (1312), Expect = 1.536e-159 Identity = 288/714 (40.34%), Postives = 403/714 (56.44%), Query Frame = 3 Query: 480 DKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNE-ESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIE--QSEKISGPA-GIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDV----------------------------RKLLNKRRNYTAP-ISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXX-XXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIY 2519 D R R ++ P+ I ++++ I E N+N EN+ TS S ++N R K I LN S + S+ + K +VL + +P + P Y +Y+EK+ EEL+ EYD+DEED+ WL NE + +S+ P IV T E ++DR EKE ES + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEP+E V+ I ARW+L CYLCKQK GA IQCHK+NCYTAFHVTCAQ+AGL+MKI+ + ++G ++K+AFC+ HSP K G + DEE G R K+ +++++K+ T P ++ P IP +L ++ I ++ K FM R+H YW +KR+ R+GVPL+RRL + A DE S + LK+WQ++R DLE+ARLL EL RKREK+KRE + ++ + L P + L + ++D+LQ D+ +IFA+PV P+Y + + PMDF+ +R K ++++Y +I L DF+LM++NC YNA++T+++ A +LR + +RQ G D TG+ +S + Sbjct: 7 DGRLHRISIFDPLPIITEDEMTAQDIAECNSNK---ENTEQTSASS-AANLSRRTASNKNKKKDIKNAYISILNHFPSSQGQSHSQHGNHCPLPKPTFRVLDSFVPT------------DAPPLPSAYYRYMEKSQEELENEAEYDMDEEDVSWLEMVNE----------------KRTSEGQP-IVSPDTFELLMDRMEKESFLESRSQVPSQSSIDEDAFCSVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPVEGVDNIPPARWKLTCYLCKQKGRGASIQCHKANCYTAFHVTCAQRAGLFMKIDPVRETTVNGTTFSVKKTAFCEAHSPE-QKEG-------SDDEETGGRVVGGRAKRGSSAYVPTPQLKKSGRSNKKEEESPKKKGKKSQEVISKK--LTTPVVAVPEIPSNRLNKVFKGIIMQKKNYFMQRLHKYWLLKRQSRNGVPLIRRLHSHLQAQKSADQAEPDEKVSAVREELKYWQKLRHDLERARLLVELIRKREKLKREQMKVQQAVMELQLTPALMLQRSILDQLQEKDSAEIFAQPVDLKEVPDYLEFVSQPMDFSTMRSKLEAHKYRSILDLEADFNLMIANCLLYNAKDTVFHRAAVRLRELGGAILRHAQRQAQNTGLDPNTGMHLPESPH 677 HSP 2 Score: 128.642 bits (322), Expect = 1.481e-29 Identity = 63/125 (50.40%), Postives = 79/125 (63.20%), Query Frame = 3 Query: 3141 QSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 +S+ LEPLDLVWAKCRGYP +P LI+DP M G+ N VPIP PP +V LG + + + FLVLFFD KRTWQWL R+KL P + + +D+ L K+ KSV AY A+ HL V Sbjct: 1064 ESDAELEPLDLVWAKCRGYPSYPALIIDPDMPEEGLLHNGVPIPVPPADVLRLGDQRQEEAGEKLFLVLFFDNKRTWQWLPRDKLLPLGMDDTVDKLRLMEGRKTSIRKSVQVAYDRAMMHLSRV 1188
BLAST of Peregrin vs. Ensembl Cavefish
Match: brpf3b (bromodomain and PHD finger containing, 3b [Source:ZFIN;Acc:ZDB-GENE-081104-468]) HSP 1 Score: 506.523 bits (1303), Expect = 1.033e-158 Identity = 264/603 (43.78%), Postives = 370/603 (61.36%), Query Frame = 3 Query: 786 PIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIE--QSEKISGPA-GIRKSAFCDVHSP----------SGYKAGVSRGMYANSDEELTSE--KPGKRQKKLKDV--------RKLLNKRRNYTAP-ISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXX-XXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIY 2519 P+P + + + P Y +Y+EK+ EEL+ EYD+DEED+ WL NE + +S+ P IV T E ++DR EKE ES + + IDEDA C VCLD C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR CL SPS PVDC LCPN+GGAFKQT+D RWAHVVC +WIPE+ FAN +FLEP+E V+ I ARW+L CYLCKQK GA IQCHK+NCYTAFHVTCAQ+AGL+MKI+ + ++G ++K+AFC+ HSP +G + R +S T + K G+ KK ++ +++++K+ T P ++ P IP +L ++ I ++ K FM R+H YW +KR+ R+GVPL+RRL + A DE S + LK+WQ++R DLE+ARLL EL RKREK+KRE + ++ + L P + L + ++D+LQ D+ +IFA+PV P+Y + + PMDF+ +R K ++++Y +I L DF+LM++NC YNA++T+++ A +LR + +RQ G D TG+ +S + Sbjct: 127 PLPKPTFRVLDSFVPTDAPPLPSAYYRYMEKSQEELENEAEYDMDEEDVSWLEMVNE----------------KRTSEGQP-IVSPDTFELLMDRMEKESFLESRSQVPSQSSIDEDAFCSVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNRGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPVEGVDNIPPARWKLTCYLCKQKGRGASIQCHKANCYTAFHVTCAQRAGLFMKIDPVRETTVNGTTFSVKKTAFCEAHSPEQKEGSDDEETGGRVVGGRAKRGSSAYVPTPQLKKSGRSNKKEEESPKKKGKKSQEVISKK--LTTPVVAVPEIPSNRLNKVFKGIIMQKKNYFMQRLHKYWLLKRQSRNGVPLIRRLHSHLQAQKSADQAEPDEKVSAVREELKYWQKLRHDLERARLLVELIRKREKLKREQMKVQQAVMELQLTPALMLQRSILDQLQEKDSAEIFAQPVDLKEVPDYLEFVSQPMDFSTMRSKLEAHKYRSILDLEADFNLMIANCLLYNAKDTVFHRAAVRLRELGGAILRHAQRQAQNTGLDPNTGMHLPESPH 710 HSP 2 Score: 126.716 bits (317), Expect = 5.954e-29 Identity = 62/120 (51.67%), Postives = 76/120 (63.33%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELG---RLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIV 3506 LEPLDLVWAKCRGYP +P LI+DP M G+ N VPIP PP +V LG + + + FLVLFFD KRTWQWL R+KL P + + +D+ L K+ KSV AY A+ HL V Sbjct: 1028 LEPLDLVWAKCRGYPSYPALIIDPDMPEEGLLHNGVPIPVPPADVLRLGDQRQEEAGEKLFLVLFFDNKRTWQWLPRDKLLPLGMDDTVDKLRLMEGRKTSIRKSVQVAYDRAMMHLSRV 1147
BLAST of Peregrin vs. Ensembl Sea Lamprey
Match: brpf3a (bromodomain and PHD finger containing, 3a [Source:ZFIN;Acc:ZDB-GENE-130530-730]) HSP 1 Score: 183.341 bits (464), Expect = 3.247e-48 Identity = 92/226 (40.71%), Postives = 149/226 (65.93%), Query Frame = 3 Query: 1824 KLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXX-XXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGL 2498 +LK+I + ++ K+EFM R+ +YW +KR+ R+GVPLLRRL + S+ + DE +S + LK+WQ++RQDLE+ARLL EL RKREK+KRE + ++ + L P + L++ +++LQ DT IFAEPV+ P+Y I+ PMDF+ +R + +++ Y ++ DFDL+++NC +YN+++TI+Y A +LR + + + RQ ++IGFD TG+ Sbjct: 1 RLKKIVSRVTMQRKKEFMTRLQSYWTLKRQSRNGVPLLRRLQSHLQSQRSAEQRENDEKNSALKEQLKYWQRLRQDLERARLLIELIRKREKLKREQIKVQQAVLEMQLTPFLVLLRRSLEQLQERDTNNIFAEPVSIEEVPDYLDYIKKPMDFSGMRARLEAHGYCTLDDFENDFDLIVANCMQYNSKDTIFYKAAVRLRDQGGAILRQARRQAEKIGFDYATGM 226 HSP 2 Score: 123.635 bits (309), Expect = 5.874e-29 Identity = 61/123 (49.59%), Postives = 74/123 (60.16%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCE 3515 +EPLDLVWAKCRGYP +P LI+DP + G N VPIP PP +V LG + + FLVLFFD KRTWQWL R KL P ++E +D+ + KS KSV AY A+ H V E Sbjct: 577 MEPLDLVWAKCRGYPSYPALIIDPKIPREGFYHNSVPIPLPPMDVLTLGEAMAAEAGESLFLVLFFDNKRTWQWLPRSKLMPLGIEESLDKLKMMEGRKSNIRKSVQIAYDRAMTHRSRVQGE 699
BLAST of Peregrin vs. Ensembl Sea Lamprey
Match: mllt10 (MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:ZFIN;Acc:ZDB-GENE-041114-176]) HSP 1 Score: 144.821 bits (364), Expect = 3.155e-35 Identity = 89/248 (35.89%), Postives = 130/248 (52.42%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKC-LHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN------VGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH-------SPSG---YKAGVSRGMYANSDEELTSEKPG------KRQKKLKDVRKLL-----NKRRNYTAP 1796 C VC D N +++CD C++AVHQ CYG+ +VP G W CRKC + V C LCP+K GA K+T++ WAHVVC L+IPE+ FAN+ +EPI ++ + R+ CYLC+++ GAC+ C+K C AFHVTCAQ AGL + E+ G ++ +C H P+G + AG+ + D+ +K KR K++ + LL + YT+P Sbjct: 9 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVHVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIV-LQYVPHDRYNKTCYLCEEQGRESKAATGACMTCNKHGCRQAFHVTCAQMAGLLCE----EEGVGADNVKYCGYCKYHYSKMQKGRPAGRSAFDAGLGEAPSHSQDKHERDKKKNREKEKQKRHKRVGEPSPLLPSLTVTTEKTYTSP 251
BLAST of Peregrin vs. Ensembl Sea Lamprey
Match: KDM4C (lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]) HSP 1 Score: 123.25 bits (308), Expect = 8.556e-29 Identity = 58/143 (40.56%), Postives = 86/143 (60.14%), Query Frame = 3 Query: 1170 DNSNVILFCDVCNLAVHQECYGVPY--VPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN---VGACIQCHKSNCYTAFHVTCAQQAGLYMK 1583 D ++ ++ C C L VH CYGV + +G W C +C + + VDCCLC +GGA +QT DNRW HV+C + + E F N++ P+ ++ +I RW+L C C++++ GAC+QC C T FHVTCA AG+ M+ Sbjct: 469 DGTSTLISCAKCCLQVHASCYGVGAQSLSDG-WKCSRCA-AEAWTVDCCLCNLRGGALQQTTDNRWVHVMCAVAVTEARFVNVMERRPV-DISRIPPPRWKLKCIFCRKQHRKVQGACVQCSYGRCPTPFHVTCAHAAGVLME 608
BLAST of Peregrin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008687.1 (pep scaffold:Pmarinus_7.0:GL495059:436:1819:-1 gene:ENSPMAG00000007864.1 transcript:ENSPMAT00000008687.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 109.768 bits (273), Expect = 5.023e-28 Identity = 52/126 (41.27%), Postives = 72/126 (57.14%), Query Frame = 3 Query: 1035 VDQATMEYVIDRFEKECHFESI----TGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQT-NDNRWAHVVCGLWIPEI 1397 V + ++E + R E+ C ++ T + L + D D VCDVC ++ N ++FCD C++ VHQ CYG+ VP G WLCR C + P C LCP + GA K T +WAHV C LWIPE+ Sbjct: 24 VRERSLEAALSRLERRCADSALRALSTEAALGIEFDADVVCDVCRSPHAEDGNEMVFCDKCDVCVHQACYGIACVPAGSWLCRVCDRGVAAP-RCQLCPRRDGAMKPTRGGGKWAHVSCALWIPEV 148
BLAST of Peregrin vs. Ensembl Sea Lamprey
Match: KDM4C (lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]) HSP 1 Score: 101.679 bits (252), Expect = 1.285e-23 Identity = 46/109 (42.20%), Postives = 68/109 (62.39%), Query Frame = 3 Query: 1266 CRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN---VGACIQCHKSNCYTAFHVTCAQQAGLYMK 1583 C +C + + VDCCLC +GGA +QT DNRW HV+C + + E F N++ P++ + +I RW+L C C++++ GAC+QC C T FHVTCA AG+ M+ Sbjct: 2 CSRCA-AEAWTVDCCLCNLRGGALQQTTDNRWVHVMCAVAVTEARFVNVMERRPVD-ISRIPPPRWKLKCIFCRKQHRKVQGACVQCSYGRCPTPFHVTCAHAAGVLME 108
BLAST of Peregrin vs. Ensembl Yeast
Match: NTO1 (Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 [Source:SGD;Acc:S000006235]) HSP 1 Score: 241.891 bits (616), Expect = 9.836e-68 Identity = 133/378 (35.19%), Postives = 204/378 (53.97%), Query Frame = 3 Query: 1077 KECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYM---KIEQSEKISGPAGIRKS--AFCDVHSPSGYKA---GVSRGM-YANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIP---PEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMI-SNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMK 2171 ++C + GS+ + D C VCL DN N I+FCD C++AVHQECYG+ ++PEG+WLCR+C+ S ++ C +CP+ GAFKQT+ W H +C LW+PE+ F+NL ++EPIE V+ + +RW+L CY+CK+K +GACIQC + NC+TA+HVTCA++AGLYM K E S + S +FC H+P G++ G+++ Y + L +E P + + K + + P PV P E L+++ D + N I YW MKRE G PL + S+ + E + + + F +DL + + L+ L +KR + L R+ + D + P L+K Sbjct: 244 RDCKNYELYGSDDGTGLSMDQACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTGSWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKK-MGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAPRGWQTSIEGINKARKYFSLLSTLQTETPQHNEANDRTNSKF--NKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKRELTGGTPL---------TACFENNSLGSLTEEQVQTRIDFANDQLEDLYRLKELTTLVKKRTQASNSLSRSRKKVFDIVKSPQKYLLK 609
BLAST of Peregrin vs. Ensembl Yeast
Match: SNT2 (Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitination, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003099]) HSP 1 Score: 72.4034 bits (176), Expect = 4.307e-13 Identity = 49/185 (26.49%), Postives = 78/185 (42.16%), Query Frame = 3 Query: 1137 AVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPY---------VPEGQWLCRKCLH--SP--SHPVDCCLCPNKG---------------GAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKIS 1607 C VC + DN N + C C L VH CY + + +WLC C + +P S C +CP K A K T+ W H+VC L+ +I + N ++P N + R C +C+ N G ++C+K C +H+TCAQ + + + + + +S Sbjct: 1039 TFCSVCKEKFNDNDNYEVVCGNCGLTVHYFCYAIKLPKDMKKNTNLKTFKWLCDPCSNDLNPIISTTYQCSMCPTKDYDYDRYRSQSFKICPDALKCTSLGTWVHLVCSLFNEDIKYGNGQSMQPALNTTAVLIKHSRFTCGVCRI-NGGGLVKCNK--CQYRYHITCAQNSSNFKLMFEKKNMS 1220
BLAST of Peregrin vs. Ensembl Yeast
Match: GCN5 (Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]) HSP 1 Score: 58.151 bits (139), Expect = 5.423e-9 Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 3 Query: 2166 MKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKL 2420 +++++ ELQ F +PV P+Y I+ PMD + + K +SN+Y +E D L+ +NC+ YN NT YY A++L Sbjct: 336 IQNILTELQNHAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRL 420
BLAST of Peregrin vs. Ensembl Yeast
Match: BDF2 (Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002228]) HSP 1 Score: 49.2914 bits (116), Expect = 3.244e-6 Identity = 27/85 (31.76%), Postives = 46/85 (54.12%), Query Frame = 3 Query: 2178 IDELQTLDTGKIFAEPVTDAMA---PNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLR 2423 I + L + F +PV D +A P+Y +Q PMD +LI K + N Y ++E++ DF M+ NC +N + +MA +++ Sbjct: 146 IKATKRLKDARPFLKPV-DPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQ 229
BLAST of Peregrin vs. Ensembl Nematostella
Match: EDO40569 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Q6]) HSP 1 Score: 525.783 bits (1353), Expect = 1.971e-170 Identity = 269/590 (45.59%), Postives = 371/590 (62.88%), Query Frame = 3 Query: 771 KVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSD-EELTSE---KPGKRQKK-LKDVRKLLNKRRNYTAP-ISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSE---MISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKS 2513 K + P+ ++ E + + + P Y +++E+T EE+DE+VEYD+DEED WL N ++R + P V Q E ++DR EKE +FES T + + IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNK GAFKQT+D RW HV C LWIPE+ FAN +FLEPI++++ I +ARW+L CY+CK++ GACIQC K+NCYTAFHVTCAQQAGLYMKIE + +G +RK+AFCD+HSP+ + +E+ S+ K GK K+ +K RKLL++++ P ++ P IP +L +I + + K +F++ + +YW +KR+ R+GVPLLRRL A+ E S M L FWQ++R DLE+ARLL EL RKREK+KRE + + D L P +++ +D++QT D G+IF++PV +Y +I+ PMDF+ +R + SN Y IE+ DF+L++ NC YNA++TIYY A KLR + P+ RQ + G D TGL ++ Sbjct: 154 KKTELPLAVYCE-ADEAFCLPDAPARPTTYFRFIEQTTEEMDEMVEYDMDEEDYAWLDFVN---------------DKRKADSIAP--VSQEVFETLMDRLEKESYFESQTTCDPNQYIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRVVDCVLCPNKTGAFKQTDDGRWGHVSCALWIPEVCFANTVFLEPIDSIDNIPSARWKLTCYICKRRQ-GACIQCFKTNCYTAFHVTCAQQAGLYMKIEPVKGENGHITVRKNAFCDIHSPNSSEENEGEERSEEEKTKEVKSKAAVKTGKTNKRSIKKFRKLLSEKKTMPVPVVNIPFIPAHRLGKIVSRVAMAKKAQFVHALQSYWMLKRQSRNGVPLLRRLQATHLSQKGTGDESSERSERIRAMKEQLHFWQRLRHDLERARLLVELIRKREKLKREHVKVKQHVVDLKLQPLNIVLRKTLDQVQTKDPGEIFSDPVDTNEVLDYLDVIKQPMDFSTMRSRIDSNFYHTIEQFEADFNLIIENCMAYNAQDTIYYRAALKLRDQGRPIIRAARRQIERAGIDPVTGLHTKEA 724
BLAST of Peregrin vs. Ensembl Nematostella
Match: EDO49715 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFG5]) HSP 1 Score: 217.624 bits (553), Expect = 1.800e-61 Identity = 138/415 (33.25%), Postives = 207/415 (49.88%), Query Frame = 3 Query: 909 YDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECH----FESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNR-WAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMK--IEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLK-DVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKF----WQQIRQDLEKARLLSELSRKREKIKRELFR 2117 YDL+ D+ WL N + +D+ T+E I E +C+ + +T L + DE CDVC + N ++FCD C++ VHQ CYG+ +P G WLC+ C + P C LC GGA K+ + + HV C LW+PE+ F N+ +EPI VEKI +RW L CYLCK+K VGACIQC +C TAFHVTC Q GL M+ ++ +E G+R ++C H G S G S + ++ P + +K+K D + N+R+ + + EI ++ + +E + IHAYW +KR+ R VPL+ K + +G++++ NL+ ++R DLE+ R L + KREK++RELFR Sbjct: 73 YDLNRTDVEWLTALNSITLSCLGKTE----------------LDEGTLEKAIAYMEDKCYENMGYAIVTQKGLSIEYDESVCCDVCQSPESEEGNEMVFCDSCDICVHQACYGIQSIPSGSWLCQPCRWGVAKP-PCKLCSACGGAMKKAKGGKTYIHVSCALWVPEVGFGNVERMEPIIKVEKIPTSRWNLVCYLCKEK-VGACIQCSVKSCVTAFHVTCGFQEGLDMRTILDDTEV----DGVRHVSYCSKHGYKNKSPGKSPGRPPKSPRKSPNKSPPRSPEKIKQDKEEAENQRQKRLKQMEGEFYNYVDVGEIAKDLAL--PKELASHIHAYWTLKRKARDDVPLVPPTPQQQEKLSGK-----QGAADISKNLQVQIERLMKMRCDLERLRNLCYMVGKREKMRRELFR 458
BLAST of Peregrin vs. Ensembl Nematostella
Match: EDO43778 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXH9]) HSP 1 Score: 140.198 bits (352), Expect = 7.477e-38 Identity = 73/178 (41.01%), Postives = 103/178 (57.87%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKCLHSPS-HPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNV------GACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH 1649 C VC D + N +++CD CN+AVHQ CYG+ VP+G W CRKC V C LCP+K GA K+T++ WAHVVC L+IPE+ F N+ +EPI + + R+ CY+C+++ G C+ C+K C FHVTCAQ GL E+++ SGP ++ +C H Sbjct: 9 CCVCSDERGWDENPLVYCDGHGCNVAVHQACYGIVQVPKGPWFCRKCESQERIARVKCELCPSKVGALKRTDNGGWAHVVCALYIPEVRFGNVSTMEPIL-LASVPHERYLKTCYICEERGKESRTAHGGCMNCNKLGCKQTFHVTCAQSCGLL--CEENDGQSGPT-VKYVGYCQFH 182
BLAST of Peregrin vs. Ensembl Nematostella
Match: EDO45971 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR96]) HSP 1 Score: 82.8037 bits (203), Expect = 4.762e-16 Identity = 44/108 (40.74%), Postives = 60/108 (55.56%), Query Frame = 3 Query: 2163 LMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVF--ERYERQYDEIGF 2480 +++L LQ D FA PV DA+AP YS++I PMDF+ I+ K SN Y IE R DF LM +N YNA +TIY+ A ++ + +R + Y IGF Sbjct: 164 CLENLHITLQRKDIQGFFAYPVNDAIAPGYSRVITHPMDFSTIKTKIDSNSYTTIEAFRDDFYLMCNNAMVYNAPDTIYFKAAKRIMQIGAKMMTNDRIKNMYRSIGF 271
BLAST of Peregrin vs. Ensembl Nematostella
Match: EDO44902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUH0]) HSP 1 Score: 52.373 bits (124), Expect = 9.106e-8 Identity = 26/85 (30.59%), Postives = 43/85 (50.59%), Query Frame = 3 Query: 2166 MKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKL 2420 +K ++ LQ+ F EPV+ P Y +I+ PMD + + K S +Y +E+ D + NC+ +N ++T YY A L Sbjct: 56 LKRMLRSLQSHKMAWPFLEPVSGLDVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVL 140
BLAST of Peregrin vs. Ensembl Medaka
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100302418]) HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0 Identity = 330/846 (39.01%), Postives = 460/846 (54.37%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLI-----------TIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRS--FSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK------AGVSRGMYANSDEEL-----------------TSEKPGKRQK-----KLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMIS------------NLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANK 2510 +D DV F +R KPP+ CP + C K+++S+S I HL T+ +K ++ + + D D + +H+ +T ++YA ++ V L+ R R ++ I + +ED + A L + T + + G + RS S K K + + D + N + ++ P +F E L+ + P Y +Y++K+AEELDE VEYD+DEED IWL N+ K RR P Q EY++DR EKE +FES ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G G S G ++S+ EL +SE+ KR K K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+H+YW +KR+ R+GVPLLRRL + S+++ S LK WQ++R DLE+ARLL EL RKREK+KRE + + + L P + L++ +++LQ DT F EPV P+Y + I PMDF + +S+ Y+ E DF L+++NC +YNA++T++Y A +LR V +RQ D IGFD E+G+ ++ Sbjct: 3 LDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPTPAQTMPQKKRKGRPPRASLTGSADTD-DGGGNGGQGHEGNTPGSPSRSEHSHSPGRET--MTYAQAQSMVELEIQGRVHRISIFENIDVVSEED--SDADDALPSGTGNSTGGVCNGGDGGGGGSEVGGSCKDRSDITSSNGAKATPKTGKHKSKAKKK--DGSSHHHNSQSGPAVKLPEAVFRE---LDQDRPDAPPRPSSYYRYIDKSAEELDEEVEYDIDEEDYIWLGIMND-------------KRRRDGVPPIP----QEVFEYLMDRLEKESYFESHNKTDPSTLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASMGS-SHSEGELEDDDEPSLCNDDDSKGWSSER-AKRAKAKSRLKMKKARKILAERRAAAPVVSVPCIPPHRLSKITSNLTVPRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLPSHRHVEPHPPQPSAQVASRDSEEKQTALKEQLKAWQRLRHDLERARLLVELIRKREKLKRETIKVQQMVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLEEVPDYLEHIDTPMDFQTMWNLLESHRYLTFEAFEGDFGLIVNNCLKYNAKDTVFYRAALRLREMGGAVIRAAKRQADRIGFDYESGMHLHR 818 HSP 2 Score: 106.686 bits (265), Expect = 1.085e-22 Identity = 62/124 (50.00%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ VPIP PP +V +LG + +H FLVLFFD KRTWQWL R KL P V +++D+ + KS KSV AY A++H V +P Sbjct: 1152 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPVDVLKLGEQMTQEAREHLFLVLFFDNKRTWQWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQHRSKVQGDP 1275
BLAST of Peregrin vs. Ensembl Medaka
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100302418]) HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0 Identity = 330/846 (39.01%), Postives = 460/846 (54.37%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLI-----------TIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRS--FSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK------AGVSRGMYANSDEEL-----------------TSEKPGKRQK-----KLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMIS------------NLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANK 2510 +D DV F +R KPP+ CP + C K+++S+S I HL T+ +K ++ + + D D + +H+ +T ++YA ++ V L+ R R ++ I + +ED + A L + T + + G + RS S K K + + D + N + ++ P +F E L+ + P Y +Y++K+AEELDE VEYD+DEED IWL N+ K RR P Q EY++DR EKE +FES ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G G S G ++S+ EL +SE+ KR K K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+H+YW +KR+ R+GVPLLRRL + S+++ S LK WQ++R DLE+ARLL EL RKREK+KRE + + + L P + L++ +++LQ DT F EPV P+Y + I PMDF + +S+ Y+ E DF L+++NC +YNA++T++Y A +LR V +RQ D IGFD E+G+ ++ Sbjct: 3 LDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPTPAQTMPQKKRKGRPPRASLTGSADTD-DGGGNGGQGHEGNTPGSPSRSEHSHSPGRET--MTYAQAQSMVELEIQGRVHRISIFENIDVVSEED--SDADDALPSGTGNSTGGVCNGGDGGGGGSEVGGSCKDRSDITSSNGAKATPKTGKHKSKAKKK--DGSSHHHNSQSGPAVKLPEAVFRE---LDQDRPDAPPRPSSYYRYIDKSAEELDEEVEYDIDEEDYIWLGIMND-------------KRRRDGVPPIP----QEVFEYLMDRLEKESYFESHNKTDPSTLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASMGS-SHSEGELEDDDEPSLCNDDDSKGWSSER-AKRAKAKSRLKMKKARKILAERRAAAPVVSVPCIPPHRLSKITSNLTVPRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLPSHRHVEPHPPQPSAQVASRDSEEKQTALKEQLKAWQRLRHDLERARLLVELIRKREKLKRETIKVQQMVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLEEVPDYLEHIDTPMDFQTMWNLLESHRYLTFEAFEGDFGLIVNNCLKYNAKDTVFYRAALRLREMGGAVIRAAKRQADRIGFDYESGMHLHR 818 HSP 2 Score: 106.686 bits (265), Expect = 1.085e-22 Identity = 62/124 (50.00%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ VPIP PP +V +LG + +H FLVLFFD KRTWQWL R KL P V +++D+ + KS KSV AY A++H V +P Sbjct: 1152 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPVDVLKLGEQMTQEAREHLFLVLFFDNKRTWQWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQHRSKVQGDP 1275
BLAST of Peregrin vs. Ensembl Medaka
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100302418]) HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0 Identity = 329/845 (38.93%), Postives = 458/845 (54.20%), Query Frame = 3 Query: 144 IDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLI-----------TIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRS--FSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK------AGVSRGMYANSDEELT----------------SEKPGKRQK-----KLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMIS------------NLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANK 2510 +D DV F +R KPP+ CP + C K+++S+S I HL T+ +K ++ + + D D + +H+ +T ++YA ++ V L+ R R ++ I + +ED + A L + T + + G + RS S K K + + D + N + ++ P +F E L+ + P Y +Y++K+AEELDE VEYD+DEED IWL N+ K RR P Q EY++DR EKE +FES ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G G S G ++S+ EL S + KR K K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+H+YW +KR+ R+GVPLLRRL + S+++ S LK WQ++R DLE+ARLL EL RKREK+KRE + + + L P + L++ +++LQ DT F EPV P+Y + I PMDF + +S+ Y+ E DF L+++NC +YNA++T++Y A +LR V +RQ D IGFD E+G+ ++ Sbjct: 3 LDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPTPAQTMPQKKRKGRPPRASLTGSADTD-DGGGNGGQGHEGNTPGSPSRSEHSHSPGRET--MTYAQAQSMVELEIQGRVHRISIFENIDVVSEED--SDADDALPSGTGNSTGGVCNGGDGGGGGSEVGGSCKDRSDITSSNGAKATPKTGKHKSKAKKK--DGSSHHHNSQSGPAVKLPEAVFRE---LDQDRPDAPPRPSSYYRYIDKSAEELDEEVEYDIDEEDYIWLGIMND-------------KRRRDGVPPIP----QEVFEYLMDRLEKESYFESHNKTDPSTLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASMGS-SHSEGELEDDDEPSLCNDDDSKGWSSERAKRAKAKSRLKMKKARKILAERRAAAPVVSVPCIPPHRLSKITSNLTVPRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLPSHRHVEPHPPQPSAQVASRDSEEKQTALKEQLKAWQRLRHDLERARLLVELIRKREKLKRETIKVQQMVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLEEVPDYLEHIDTPMDFQTMWNLLESHRYLTFEAFEGDFGLIVNNCLKYNAKDTVFYRAALRLREMGGAVIRAAKRQADRIGFDYESGMHLHR 818 HSP 2 Score: 106.301 bits (264), Expect = 1.170e-22 Identity = 62/124 (50.00%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ VPIP PP +V +LG + +H FLVLFFD KRTWQWL R KL P V +++D+ + KS KSV AY A++H V +P Sbjct: 1130 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPVDVLKLGEQMTQEAREHLFLVLFFDNKRTWQWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQHRSKVQGDP 1253
BLAST of Peregrin vs. Ensembl Medaka
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100302418]) HSP 1 Score: 555.058 bits (1429), Expect = 1.033e-176 Identity = 287/623 (46.07%), Postives = 381/623 (61.16%), Query Frame = 3 Query: 735 DKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK------AGVSRGMYANSDEELT----------------SEKPGKRQK-----KLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANK 2510 D + N + ++ P +F E L+ + P Y +Y++K+AEELDE VEYD+DEED IWL N+ K RR P Q EY++DR EKE +FES ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G G S G ++S+ EL S + KR K K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+H+YW +KR+ R+GVPLLRRL +E + + LK WQ++R DLE+ARLL EL RKREK+KRE + + + L P + L++ +++LQ DT F EPV P+Y + I PMDF + +S+ Y+ E DF L+++NC +YNA++T++Y A +LR V +RQ D IGFD E+G+ ++ Sbjct: 156 DGSSHHHNSQSGPAVKLPEAVFRE---LDQDRPDAPPRPSSYYRYIDKSAEELDEEVEYDIDEEDYIWLGIMND-------------KRRRDGVPPIP----QEVFEYLMDRLEKESYFESHNKTDPSTLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASMGS-SHSEGELEDDDEPSLCNDDDSKGWSSERAKRAKAKSRLKMKKARKILAERRAAAPVVSVPCIPPHRLSKITSNLTVPRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLPSHRHRDS--EEKQTALKEQLKAWQRLRHDLERARLLVELIRKREKLKRETIKVQQMVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLEEVPDYLEHIDTPMDFQTMWNLLESHRYLTFEAFEGDFGLIVNNCLKYNAKDTVFYRAALRLREMGGAVIRAAKRQADRIGFDYESGMHLHR 754 HSP 2 Score: 108.997 bits (271), Expect = 1.755e-23 Identity = 70/163 (42.94%), Postives = 90/163 (55.21%), Query Frame = 3 Query: 3057 EDSTQDNSNNIFDSFDASEEDETEGIKSQSNI------RLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 EDS+++ S DS+ KS + LE LDLVWAKCRGYP +P LI+DP M G+ VPIP PP +V +LG + +H FLVLFFD KRTWQWL R KL P V +++D+ + KS KSV AY A++H V +P Sbjct: 1019 EDSSEETSGTENDSYSVGGSRSVSHCKSGCWMTSDDYSSLEALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPVDVLKLGEQMTQEAREHLFLVLFFDNKRTWQWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQHRSKVQGDP 1181
BLAST of Peregrin vs. Ensembl Medaka
Match: brpf1 (bromodomain and PHD finger containing 1 [Source:NCBI gene;Acc:100302418]) HSP 1 Score: 554.288 bits (1427), Expect = 5.533e-176 Identity = 286/634 (45.11%), Postives = 380/634 (59.94%), Query Frame = 3 Query: 735 DKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAG----IRKSAFCDVHSPSGYK---AGVSRGMYANS------------------DEELTSEKPGKRQK-----KLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMIS------------NLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANK 2510 D + N + ++ P +F E L+ + P Y +Y++K+AEELDE VEYD+DEED IWL N+ K RR P Q EY++DR EKE +FES ++ IDEDAVC +C DG C NSNVILFCD+CNLAVHQECYGVPY+PEGQWLCR+CL SPS VDC LCPNKGGAFKQT+D+RWAHVVC LWIPE+ FAN +FLEPI+++E I ARW+L CY+CKQ+ GACIQCHK+NCYTAFHVTCAQQAGLYMK+E + +G G +RK+A+CD+H+P G GV +S D + S + KR K K+K RK+L +RR +S P IPP +L +IT N+ V K +FM R+H+YW +KR+ R+GVPLLRRL + S+++ S LK WQ++R DLE+ARLL EL RKREK+KRE + + + L P + L++ +++LQ DT F EPV P+Y + I PMDF + +S+ Y+ E DF L+++NC +YNA++T++Y A +LR V +RQ D IGFD E+G+ ++ Sbjct: 151 DGSSHHHNSQSGPAVKLPEAVFRE---LDQDRPDAPPRPSSYYRYIDKSAEELDEEVEYDIDEEDYIWLGIMND-------------KRRRDGVPPIP----QEVFEYLMDRLEKESYFESHNKTDPSTLIDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDSRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRE-TGANGTSFSVRKTAYCDIHTPPGSARPLGGVGGASMGSSHSEGELEDDDEPSLCNDDDSKGWSSERAKRAKAKSRLKMKKARKILAERRAAAPVVSVPCIPPHRLSKITSNLTVPRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLPSHRHVEPHPPQPSAQVASRDSEEKQTALKEQLKAWQRLRHDLERARLLVELIRKREKLKRETIKVQQMVLEMQLTPFLVLLRSTLEQLQERDTNNFFTEPVPLEEVPDYLEHIDTPMDFQTMWNLLESHRYLTFEAFEGDFGLIVNNCLKYNAKDTVFYRAALRLREMGGAVIRAAKRQADRIGFDYESGMHLHR 763 HSP 2 Score: 106.686 bits (265), Expect = 9.472e-23 Identity = 62/124 (50.00%), Postives = 77/124 (62.10%), Query Frame = 3 Query: 3156 LEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGR---LHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEP 3518 LE LDLVWAKCRGYP +P LI+DP M G+ VPIP PP +V +LG + +H FLVLFFD KRTWQWL R KL P V +++D+ + KS KSV AY A++H V +P Sbjct: 1097 LEALDLVWAKCRGYPSYPALIIDPKMPREGVFHRGVPIPVPPVDVLKLGEQMTQEAREHLFLVLFFDNKRTWQWLPRSKLVPLGVDQELDKEKMLEGRKSNIRKSVQVAYHRAMQHRSKVQGDP 1220
BLAST of Peregrin vs. Planmine SMEST
Match: SMESG000047551.1 (SMESG000047551.1) HSP 1 Score: 2257.64 bits (5849), Expect = 0.000e+0 Identity = 1150/1156 (99.48%), Postives = 1152/1156 (99.65%), Query Frame = 3 Query: 135 MDDIDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKIPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLXXXXXXXXXNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKDLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDAHIYQLEKELNKVPQPSFGKLLIETHNQIYPPRXXXXXXXXXXXXXXMKTGKESNSSNVLSEQQSKTEEHLESIEEMADSQQNYSLRKMPAXXXXXXXXXXXXXXXXXXKTDNNEESSNNYFRVSSTHTDPDSTFDAYKSEETKLNSSISFNDYTKNPEIAHESQDVDDEDSTQDNSNNIFDSFDASEEDETEGIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPYDQFHFDEEISSPFLPRAAASAQFRS 3602 MDDIDIDVDEFLARIRGNKPPFTCPFD CSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLK PNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLEPPKPEKKKNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRLVASSSKSNLALLSID+ SSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMK+LIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDAHIYQLEKELNKVPQ SFGKLLIETHNQIYPPRSLESYSSSQDESYSMKTGKESNSSNVLSEQQSKTEEHLESIEEMADSQQNYSLRKMPATSSTTINSISSSLRRRNNKTDNNEESSNNYFRVSSTHTDPDSTFDAYKSEETKLNSSISFNDYTKNPEIAHESQDVDDEDSTQDNSNNIFDSFDASEEDETEGIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPYDQFHFDEEISSPFLPRAAASAQFRS Sbjct: 1 MDDIDIDVDEFLARIRGNKPPFTCPFDDCSKLFRSFSAISKHLITIHKKSKEIEICEIDVINDENKDIDCNNVQSNKDNESAYLKTPNMKHTSKFVIDTIQLSYADSKKFVILQNDKRSFRCNVNVPIYISIDEDLNNTAITELNTNTVHDENSNDTSQSELSSNFKRIGIKRKRSFSLKNYKKIRKLNEESKEILSNPEDKTKEMKNKEQEKVLQTPIPIFIEDINLEYFEKETPHDVEGYVKYVEKTAEELDEIVEYDLDEEDLIWLPKCNEYLTTLEPPKPEKKKNRRASSKTCPSIVDQATMEYVIDRFEKECHFESITGSNLHNDIDEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRLVASSSKSNLALLSIDKDSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELFRNFISINDTLLYPTMNLMKNLIDELQTLDTGKIFAEPVTDAMAPNYSKIIQCPMDFTLIRKKHKSNEYINIERLRVDFDLMMSNCQRYNARNTIYYNMASKLRTESVPVFERYERQYDEIGFDKETGLFANKSIYDLVINSTFEDAHIYQLEKELNKVPQSSFGKLLIETHNQIYPPRSLESYSSSQDESYSMKTGKESNSSNVLSEQQSKTEEHLESIEEMADSQQNYSLRKMPATSSTTINSISSSLRRRNNKTDNNEESSNNYFRVSSTHTDPDSTFDAYKSEETKLNSSISFNDYTKNPEIAHESQDVDDEDSTQDNSNNIFDSFDASEEDETEGIKSQSNIRLEPLDLVWAKCRGYPWFPGLIVDPFMSSNGICDNKVPIPDPPENVRELGRLHSNQHKFLVLFFDKKRTWQWLEREKLEPFAVKEDIDRNMLQLINKSRKSKSVHQAYKDAIRHLCIVNCEPYPYDQFHFDEEISSPFLPRAAASAQFRS 1156
BLAST of Peregrin vs. Planmine SMEST
Match: SMESG000051958.1 (SMESG000051958.1) HSP 1 Score: 196.823 bits (499), Expect = 7.738e-52 Identity = 110/334 (32.93%), Postives = 170/334 (50.90%), Query Frame = 3 Query: 1128 DEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQ--TNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRXXXXXXXXXXXXXXIDEGSSEMISN---LKFWQQIRQDLEKARLLSELSRKREKIKRELF 2114 DE++ CDVC ++ N ++FC+ C + VHQ CYG+P +P G W+CR C P+ C LCPN+GGA KQ +++++WAH+ C +WIPE+ F N+ +EPI + I ARW L C+LCK N GA IQC + C AFHVTCA Q L MK ++ ++ A+C HS + S ++ + K+++ + K +N + FP + LK I +I ++I YW +KR L++ S +E + I+N + + +IR L++ARL+ ++ +REK K LF Sbjct: 186 DENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK----QEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIQKQKEFEQKFSKFVNAKELSETLHEFPKQLIDPLKSIPSDIK--------DKIFTYWTLKRTSNHFQCLIKPPSIWS----------EENLKQRINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLF 497
BLAST of Peregrin vs. Planmine SMEST
Match: SMESG000057438.1 (SMESG000057438.1) HSP 1 Score: 127.872 bits (320), Expect = 1.222e-29 Identity = 68/178 (38.20%), Postives = 96/178 (53.93%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKCLHSP-SHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN------VGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH 1649 C VCL +N I+ CD C+ VH+ CYG+ +P+G W C+KC+ + V C LCP++ GA K TN W H++C L++P F + LE I +V+K+ + C +C++ N GACIQC KS C FHVTCAQ GL +I S+ +R A+C H Sbjct: 7 CCVCLKEEPFENNPIVSCDGKNCSTTVHKACYGIQQIPDGAWFCQKCISQERTARVRCELCPSRDGALKHTNKGGWCHIICALFVPGAEFLDTERLESI-SVDKVLTDKLNKMCTICEKNNRLDRATTGACIQCVKSGCKVLFHVTCAQAQGLLTEIVNSKD-----SVRYVAYCFAH 178
BLAST of Peregrin vs. Planmine SMEST
Match: SMESG000057438.1 (SMESG000057438.1) HSP 1 Score: 127.872 bits (320), Expect = 1.223e-29 Identity = 68/178 (38.20%), Postives = 96/178 (53.93%), Query Frame = 3 Query: 1143 CDVCLDGTCDNSNVILFCDV--CNLAVHQECYGVPYVPEGQWLCRKCLHSP-SHPVDCCLCPNKGGAFKQTNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKN------VGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVH 1649 C VCL +N I+ CD C+ VH+ CYG+ +P+G W C+KC+ + V C LCP++ GA K TN W H++C L++P F + LE I +V+K+ + C +C++ N GACIQC KS C FHVTCAQ GL +I S+ +R A+C H Sbjct: 7 CCVCLKEEPFENNPIVSCDGKNCSTTVHKACYGIQQIPDGAWFCQKCISQERTARVRCELCPSRDGALKHTNKGGWCHIICALFVPGAEFLDTERLESI-SVDKVLTDKLNKMCTICEKNNRLDRATTGACIQCVKSGCKVLFHVTCAQAQGLLTEIVNSKD-----SVRYVAYCFAH 178
BLAST of Peregrin vs. Planmine SMEST
Match: SMESG000036910.1 (SMESG000036910.1) HSP 1 Score: 72.7886 bits (177), Expect = 1.356e-12 Identity = 48/138 (34.78%), Postives = 69/138 (50.00%), Query Frame = 3 Query: 1185 ILFCDVCNLAVHQECYGVPYV----------PEGQWLCRKCL-HSPSHPVDCCLCPNKGGAFKQ-TNDNR-WAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCA 1559 IL C CNL VH CYG V P+ W C +C+ +P + C LC +GGA K+ TN N WAH+VC L E++F +L+ +P + E + C +CK + +C +C ++ HVTCA Sbjct: 571 ILKCSHCNLTVHARCYGNVEVDRSLSKGECEPDQNWTCDRCVKFNPL--IHCSLCSVRGGALKKLTNRNSGWAHIVCTLACQEMVFEDLLHRKPRIRDKSTEYTSNK--CSICKGRQSQPICKCAFPDCRSSVHVTCA 704 The following BLAST results are available for this feature:
BLAST of Peregrin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Peregrin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Peregrin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Peregrin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Peregrin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of Peregrin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Peregrin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Peregrin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033182 ID=SMED30033182|Name=Peregrin|organism=Schmidtea mediterranea sexual|type=transcript|length=3768bpback to top protein sequence of SMED30033182-orf-1 >SMED30033182-orf-1 ID=SMED30033182-orf-1|Name=SMED30033182-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1157bp MDDIDIDVDEFLARIRGNKPPFTCPFDGCSKLFRSFSAISKHLITIHKKSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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