Heat shock 70 kDa protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033164 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18
Homology
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 65.4698 bits (158), Expect = 4.432e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 65.4698 bits (158), Expect = 4.957e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 65.855 bits (159), Expect = 7.400e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 65.855 bits (159), Expect = 7.844e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]) HSP 1 Score: 65.855 bits (159), Expect = 7.909e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Match: hsp-1 (Heat shock 70 kDa protein A [Source:UniProtKB/Swiss-Prot;Acc:P09446]) HSP 1 Score: 65.855 bits (159), Expect = 2.087e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Match: hsp-1 (Heat shock 70 kDa protein A [Source:UniProtKB/Swiss-Prot;Acc:P09446]) HSP 1 Score: 65.855 bits (159), Expect = 2.087e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Match: F44E5.5 (pep chromosome:WBcel235:II:11759681:11761808:1 gene:WBGene00009692.1 transcript:F44E5.5.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F44E5.5) HSP 1 Score: 63.1586 bits (152), Expect = 2.054e-11 Identity = 31/70 (44.29%), Postives = 43/70 (61.43%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCVG++++ N +G+ TTP+Y AFTDT R + A KD RN N +F+ KRL+ Sbjct: 5 KAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Match: F44E5.5 (pep chromosome:WBcel235:II:11759640:11761853:1 gene:WBGene00009692.1 transcript:F44E5.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F44E5.5) HSP 1 Score: 63.1586 bits (152), Expect = 2.054e-11 Identity = 31/70 (44.29%), Postives = 43/70 (61.43%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCVG++++ N +G+ TTP+Y AFTDT R + A KD RN N +F+ KRL+ Sbjct: 5 KAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Match: F44E5.4 (pep chromosome:WBcel235:II:11757106:11759323:-1 gene:WBGene00009691.1 transcript:F44E5.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F44E5.4) HSP 1 Score: 63.1586 bits (152), Expect = 2.054e-11 Identity = 31/70 (44.29%), Postives = 43/70 (61.43%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCVG++++ N +G+ TTP+Y AFTDT R + A KD RN N +F+ KRL+ Sbjct: 5 KAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Match: Hsc70-1 (gene:FBgn0001216 transcript:FBtr0075762) HSP 1 Score: 65.855 bits (159), Expect = 3.022e-12 Identity = 34/67 (50.75%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFT++ R I A K+ N NN IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Match: Hsc70-4 (gene:FBgn0266599 transcript:FBtr0083059) HSP 1 Score: 64.6994 bits (156), Expect = 6.754e-12 Identity = 34/67 (50.75%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Match: Hsc70-4 (gene:FBgn0266599 transcript:FBtr0337053) HSP 1 Score: 64.6994 bits (156), Expect = 6.754e-12 Identity = 34/67 (50.75%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Match: Hsc70-4 (gene:FBgn0266599 transcript:FBtr0083058) HSP 1 Score: 64.6994 bits (156), Expect = 6.754e-12 Identity = 34/67 (50.75%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Match: Hsc70-4 (gene:FBgn0266599 transcript:FBtr0083060) HSP 1 Score: 64.6994 bits (156), Expect = 6.754e-12 Identity = 34/67 (50.75%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Match: hsp70.1 (heat shock cognate 70-kd protein, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-990415-91]) HSP 1 Score: 69.3218 bits (168), Expect = 1.466e-13 Identity = 37/86 (43.02%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + +++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDPVVQSDMKHWSFK 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Match: hsp70.2 (heat shock cognate 70-kd protein, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-110405-1]) HSP 1 Score: 69.3218 bits (168), Expect = 1.466e-13 Identity = 37/86 (43.02%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + +++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDPVVQSDMKHWSFK 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Match: hspa1b (heat shock protein family A (Hsp70) member 1B [Source:ZFIN;Acc:ZDB-GENE-060503-867]) HSP 1 Score: 69.707 bits (169), Expect = 1.963e-13 Identity = 38/86 (44.19%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN IF+ KRL+ + + +++ + FK Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDAKRLIGRKFDDQVVQSDMKLWPFK 93
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Match: hsp70.1 (heat shock cognate 70-kd protein, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-990415-91]) HSP 1 Score: 69.707 bits (169), Expect = 2.203e-13 Identity = 37/86 (43.02%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + +++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDPVVQSDMKHWSFK 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Match: hsp70.3 (heat shock cognate 70-kd protein, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-110713-1]) HSP 1 Score: 69.707 bits (169), Expect = 2.245e-13 Identity = 37/86 (43.02%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + +++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDPVVQSDMKHWSFK 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Match: ENSXETT00000025573.1 (heat shock protein family A (Hsp70) member 1B [Source:NCBI gene;Acc:100485441]) HSP 1 Score: 67.3958 bits (163), Expect = 1.760e-12 Identity = 36/86 (41.86%), Postives = 50/86 (58.14%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ + +++ + FK Sbjct: 9 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNTVFDAKRLIGRKYDEPVVQSDMKHWPFK 94
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Match: tmed10 (transmembrane emp24-like trafficking protein 10 (yeast) [Source:Xenbase;Acc:XB-GENE-968508]) HSP 1 Score: 67.3958 bits (163), Expect = 1.792e-12 Identity = 36/86 (41.86%), Postives = 50/86 (58.14%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ + +++ + FK Sbjct: 9 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNTVFDAKRLIGRKYDEPVVQSDMKHWPFK 94
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Match: wdr26 (WD repeat domain 26 [Source:Xenbase;Acc:XB-GENE-993726]) HSP 1 Score: 66.6254 bits (161), Expect = 2.782e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 13 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 79
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Match: wdr26 (WD repeat domain 26 [Source:Xenbase;Acc:XB-GENE-993726]) HSP 1 Score: 66.6254 bits (161), Expect = 2.886e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 11 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 77
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Match: wdr26 (WD repeat domain 26 [Source:Xenbase;Acc:XB-GENE-993726]) HSP 1 Score: 66.6254 bits (161), Expect = 2.897e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Match: Hspa8 (heat shock protein 8 [Source:MGI Symbol;Acc:MGI:105384]) HSP 1 Score: 64.6994 bits (156), Expect = 3.416e-13 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Match: Hspa2 (heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96243]) HSP 1 Score: 67.3958 bits (163), Expect = 1.407e-12 Identity = 35/67 (52.24%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N IF+ KRL+ Sbjct: 9 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLI 75
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Match: Hspa2 (heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96243]) HSP 1 Score: 67.3958 bits (163), Expect = 1.407e-12 Identity = 35/67 (52.24%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N IF+ KRL+ Sbjct: 9 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLI 75
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Match: Hspa1a (heat shock protein 1A [Source:MGI Symbol;Acc:MGI:96244]) HSP 1 Score: 67.0106 bits (162), Expect = 1.873e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Match: Hspa1b (heat shock protein 1B [Source:MGI Symbol;Acc:MGI:99517]) HSP 1 Score: 67.0106 bits (162), Expect = 1.928e-12 Identity = 34/67 (50.75%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Match: sp|Q91233|HSP70_ONCTS (Heat shock 70 kDa protein OS=Oncorhynchus tshawytscha OX=74940 GN=hsp70 PE=2 SV=1) HSP 1 Score: 69.3218 bits (168), Expect = 2.107e-12 Identity = 37/86 (43.02%), Postives = 50/86 (58.14%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + ++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFNDQVVQADMKHWPFK 95
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Match: sp|Q9U639|HSP7D_MANSE (Heat shock 70 kDa protein cognate 4 OS=Manduca sexta OX=7130 PE=2 SV=1) HSP 1 Score: 69.3218 bits (168), Expect = 2.368e-12 Identity = 36/67 (53.73%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTDRLIGDAAKNQVAMNPNNTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Match: sp|Q05746|HSP70_PLACB (Heat shock 70 kDa protein OS=Plasmodium cynomolgi (strain Berok) OX=5828 PE=2 SV=1) HSP 1 Score: 67.781 bits (164), Expect = 6.110e-12 Identity = 35/67 (52.24%), Postives = 44/67 (65.67%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGV+R+E NDQG+ TTP+Y AFTDT R I A K+ RN N +F+ KRL+ Sbjct: 19 GIDLGTTYSCVGVWRNENVDIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVARNPENTVFDAKRLI 85
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Match: sp|P11144|HSP70_PLAFA (Heat shock 70 kDa protein OS=Plasmodium falciparum OX=5833 PE=2 SV=2) HSP 1 Score: 67.781 bits (164), Expect = 7.363e-12 Identity = 35/67 (52.24%), Postives = 44/67 (65.67%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGV+R+E NDQG+ TTP+Y AFTDT R I A K+ RN N +F+ KRL+ Sbjct: 19 GIDLGTTYSCVGVWRNENVDIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVARNPENTVFDAKRLI 85
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Match: sp|P47773|HSP7C_ICTPU (Heat shock cognate 71 kDa protein OS=Ictalurus punctatus OX=7998 GN=hsc70 PE=2 SV=1) HSP 1 Score: 67.3958 bits (163), Expect = 8.057e-12 Identity = 36/86 (41.86%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTD+ R I A K+ N N IF+ KRL+ ++++ ++ + FK Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFEDSVVQADMKHWPFK 93
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Match: K9ZRK9 (Heat shock 70kDa protein 1A (Fragment) OS=Bos indicus OX=9915 GN=HSPA1A PE=4 SV=1) HSP 1 Score: 70.0922 bits (170), Expect = 4.883e-12 Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FKQL 469 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I YA K+ N N +F+ KRL+ + + +++ + F+ + Sbjct: 5 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGYAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFRVI 92
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Match: K9ZU00 (Heat shock 70kDa protein 1A (Fragment) OS=Bos indicus x Bos taurus OX=30522 GN=HSPA1A PE=4 SV=1) HSP 1 Score: 70.0922 bits (170), Expect = 4.883e-12 Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FKQL 469 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I YA K+ N N +F+ KRL+ + + +++ + F+ + Sbjct: 5 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGYAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFRVI 92
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Match: A0A2A4AYR6 (Molecular chaperone DnaK (Fragment) OS=Pseudomonas pelagia OX=553151 GN=CO192_00790 PE=4 SV=1) HSP 1 Score: 68.5514 bits (166), Expect = 1.038e-11 Identity = 36/67 (53.73%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Match: A3E3T5 (Heat shock protein 70 (Fragment) OS=Pfiesteria piscicida OX=71001 PE=2 SV=1) HSP 1 Score: 68.5514 bits (166), Expect = 1.942e-11 Identity = 37/86 (43.02%), Postives = 50/86 (58.14%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGV++++ NDQG+ TTP+Y AFTDT R I A K RN N +F+ KRL+ + I +I + FK Sbjct: 8 GIDLGTTYSCVGVWKNDGVEIIANDQGNRTTPSYVAFTDTERLIGDAAKSQVARNPENTVFDAKRLIGRKFADPIVQADIKLWPFK 93
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Match: A0A5C6MF07 (Heat shock 70 kDa protein 1 (Fragment) OS=Takifugu flavidus OX=433684 GN=D4764_0023340 PE=4 SV=1) HSP 1 Score: 68.5514 bits (166), Expect = 2.055e-11 Identity = 37/86 (43.02%), Postives = 50/86 (58.14%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ ++ +I + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPSNTVFDAKRLIGRKLEDPTVQADIKHWPFK 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Match: ENSAMXT00000032722.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001455.1:155723:156505:1 gene:ENSAMXG00000042801.1 transcript:ENSAMXT00000032722.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.9366 bits (167), Expect = 1.899e-14 Identity = 36/86 (41.86%), Postives = 52/86 (60.47%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ ++ + +++ + F+ Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFEDPVVQSDMKHWPFQ 95
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Match: ENSAMXT00000004733.2 (pep primary_assembly:Astyanax_mexicanus-2.0:20:27541457:27560661:-1 gene:ENSAMXG00000004628.2 transcript:ENSAMXT00000004733.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 69.707 bits (169), Expect = 1.507e-13 Identity = 37/86 (43.02%), Postives = 52/86 (60.47%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVG+F+H NDQG+ TTP+Y AFTDT R I A K+ N N IF+ KRL+ ++T+ +++ + FK Sbjct: 8 GIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFEDTVVQSDMKHWPFK 93
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Match: hspa1b (heat shock protein family A (Hsp70) member 1B [Source:ZFIN;Acc:ZDB-GENE-060503-867]) HSP 1 Score: 69.707 bits (169), Expect = 1.602e-13 Identity = 38/86 (44.19%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN IF+ KRL+ + + +++ + FK Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDAKRLIGRRFDDAVVQSDMKLWPFK 93
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Match: hsc70 (heat shock cognate 71 kDa protein-like [Source:NCBI gene;Acc:103045816]) HSP 1 Score: 69.3218 bits (168), Expect = 2.349e-13 Identity = 36/86 (41.86%), Postives = 51/86 (59.30%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVG+F+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ + + +++ + FK Sbjct: 8 GIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDAVVQSDMKHWPFK 93
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Match: ENSAMXT00000037064.1 (heat shock 70 kDa protein [Source:NCBI gene;Acc:111193176]) HSP 1 Score: 68.9366 bits (167), Expect = 2.882e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 76
BLAST of Heat shock 70 kDa protein vs. Ensembl Sea Lamprey
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848]) HSP 1 Score: 55.0694 bits (131), Expect = 2.810e-9 Identity = 31/68 (45.59%), Postives = 40/68 (58.82%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTG-RWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF++ NDQG+ TP+Y AFT G R I A K+ N N +F+ KRL+ Sbjct: 37 GIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDAKRLI 104
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Match: SSA4 (Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation; SSA4 has a paralog, SSA3, that arose from the whole genome duplication [Source:SGD;Acc:S000000905]) HSP 1 Score: 60.8474 bits (146), Expect = 2.473e-11 Identity = 32/70 (45.71%), Postives = 42/70 (60.00%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCV F ++ NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ Sbjct: 3 KAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLI 72
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Match: SSA1 (ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils [Source:SGD;Acc:S000000004]) HSP 1 Score: 60.077 bits (144), Expect = 3.665e-11 Identity = 31/70 (44.29%), Postives = 42/70 (60.00%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCV F ++ NDQG+ TTP++ AFTDT R I A K+ N +N +F+ KRL+ Sbjct: 3 KAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLI 72
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Match: SSA3 (ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm; SSA3 has a paralog, SSA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000171]) HSP 1 Score: 59.3066 bits (142), Expect = 7.769e-11 Identity = 31/67 (46.27%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCV F ++ NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ Sbjct: 6 GIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLI 72
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Match: SSA2 (HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation [Source:SGD;Acc:S000003947]) HSP 1 Score: 56.9954 bits (136), Expect = 3.820e-10 Identity = 30/70 (42.86%), Postives = 40/70 (57.14%), Query Frame = 2 Query: 197 KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 K GI+ T YSCV F ++ NDQG+ TTP++ FTDT R I A K+ N N +F+ KRL+ Sbjct: 3 KAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLI 72
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Match: KAR2 (ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p [Source:SGD;Acc:S000003571]) HSP 1 Score: 55.8398 bits (133), Expect = 9.867e-10 Identity = 30/72 (41.67%), Postives = 42/72 (58.33%), Query Frame = 2 Query: 191 Y*KMSGIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 Y + GI+ T YSCV V ++ + N+QG+ TP+Y AFTD R I A K+ N N IF++KRL+ Sbjct: 49 YGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIKRLI 120
BLAST of Heat shock 70 kDa protein vs. Ensembl Nematostella
Match: EDO37280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG65]) HSP 1 Score: 65.4698 bits (158), Expect = 1.787e-12 Identity = 33/67 (49.25%), Postives = 42/67 (62.69%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AF+DT R I A K+ N N +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFSDTERLIGDAAKNQVAMNPENTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Nematostella
Match: EDO30323 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T144]) HSP 1 Score: 63.929 bits (154), Expect = 5.620e-12 Identity = 33/67 (49.25%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTD R + A K+ N N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDEERLVGDAAKNQVAMNPTNTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Nematostella
Match: EDO44530 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV88]) HSP 1 Score: 61.2326 bits (147), Expect = 4.241e-11 Identity = 32/67 (47.76%), Postives = 41/67 (61.19%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF++ NDQG+ TTP+Y FTDT R + A K+ N N IF+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVGFTDTERLVGDAAKNQVALNPENTIFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Nematostella
Match: EDO33296 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL5]) HSP 1 Score: 54.6842 bits (130), Expect = 6.764e-9 Identity = 30/68 (44.12%), Postives = 40/68 (58.82%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTG-RWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF++ NDQG+ TP+Y AFT+ G R I K+ N N +F+ KRL+ Sbjct: 37 GIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTEEGERLIGDGAKNQLTTNPENTVFDAKRLI 104
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Match: hspa8b (heat shock cognate 70 kDa protein [Source:NCBI gene;Acc:100125490]) HSP 1 Score: 68.9366 bits (167), Expect = 3.553e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPNNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Match: hspa8b (heat shock cognate 70 kDa protein [Source:NCBI gene;Acc:100125490]) HSP 1 Score: 68.5514 bits (166), Expect = 3.667e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPNNTVFDAKRLI 74
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Match: HSPA2 (heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235]) HSP 1 Score: 68.1662 bits (165), Expect = 5.236e-13 Identity = 37/92 (40.22%), Postives = 51/92 (55.43%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FKQLYNIT 481 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ + ++ + FK + I Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPSNTVFDAKRLIGRRFDEPVVQADMKHWPFKVMKEIA 98
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Match: ENSORLT00000043909.1 (pep primary_assembly:ASM223467v1:8:793349:795333:-1 gene:ENSORLG00000028255.1 transcript:ENSORLT00000043909.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 5.594e-13 Identity = 37/92 (40.22%), Postives = 51/92 (55.43%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FKQLYNIT 481 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ + ++ + FK + I Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPSNTVFDAKRLIGRRFDEPVVQADMKHWPFKVMKEIA 98
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Match: ENSORLT00000042552.1 (pep primary_assembly:ASM223467v1:8:710990:713238:-1 gene:ENSORLG00000027683.1 transcript:ENSORLT00000042552.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 66.6254 bits (161), Expect = 8.413e-13 Identity = 36/86 (41.86%), Postives = 49/86 (56.98%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLVEMSNKNTINMTEITQY*FK 463 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N +N +F+ KRL+ + ++ + FK Sbjct: 10 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPSNTVFDAKRLIGRRFDEPVVQADMKHWPFK 95
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Match: SMESG000051815.1 (SMESG000051815.1) HSP 1 Score: 68.5514 bits (166), Expect = 3.557e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 73
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Match: SMESG000051570.1 (SMESG000051570.1) HSP 1 Score: 68.1662 bits (165), Expect = 3.846e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 73
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Match: SMESG000051567.1 (SMESG000051567.1) HSP 1 Score: 68.1662 bits (165), Expect = 3.846e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 73
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Match: SMESG000051541.1 (SMESG000051541.1) HSP 1 Score: 68.1662 bits (165), Expect = 3.846e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 73
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Match: SMESG000051540.1 (SMESG000051540.1) HSP 1 Score: 68.1662 bits (165), Expect = 3.846e-13 Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 206 GIEYSTNYSCVGVFRHE*S*N*GNDQGDHTTPNYGAFTDTGRWIEYATKDPDMRNTNNMIFEVKRLV 406 GI+ T YSCVGVF+H NDQG+ TTP+Y AFTDT R I A K+ N NN +F+ KRL+ Sbjct: 7 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLI 73 The following BLAST results are available for this feature:
BLAST of Heat shock 70 kDa protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Heat shock 70 kDa protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Heat shock 70 kDa protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Heat shock 70 kDa protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033164 ID=SMED30033164|Name=Heat shock 70 kDa protein|organism=Schmidtea mediterranea sexual|type=transcript|length=676bpback to top protein sequence of SMED30033164-orf-1 >SMED30033164-orf-1 ID=SMED30033164-orf-1|Name=SMED30033164-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=121bp WSYFSRSAKCLLYWNHCFYCRVYSYRHFCHWNCRGLLLYFETDIDCGKIWback to top Annotated Terms
The following terms have been associated with this transcript:
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