Rhophilin-2-like Protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033108 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Match: RHPN2 (rhophilin Rho GTPase binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19974]) HSP 1 Score: 258.07 bits (658), Expect = 3.302e-75 Identity = 160/559 (28.62%), Postives = 295/559 (52.77%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQII----SQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL+++ + +++ ++ +E+ F S+L++ KEELE N ++ YQ+ + +P+IP+ +K T D+DF ++ + HY ED Y + I + R+A + P R G+ + Y+ + +E RFF P R G++F+W D TGVP Q+ + EK+ ++FN GALY+Q+ + + TQAGLE + + F + N+L F + PS DM P ML +L +M QA E F + + + F ++ + E+ + +++ ++++++ ++ E+IP +W +L VK+++Y ALA+ A I + D++ QE + L + + + P L + + L K + A+ EES++ A++ K LR++ L L + +L E DLL+ ++A + V II S+ +D F+ LGP+ +F++ + P R + ++ GFT++G P++V ++ +A +G + GD+++S+ D +W
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGFVESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPGIRNEFFMLVKVAQ---EAAKVGEVYQQLHAAMSQAPVK--ENIPYSWASLACVKAHHYAALAHYFTAILLIDHQVKPGTDLDHQEKCLSQLYDHMPEGLTP----LATLKNDQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQER--SRLTYAQHQEEDDLLNL----IDAPSVVAKTEQEVDIILPQFSKLTVTDFFQKLGPLSVFSANKRWTPPRSIRFTAEEG-DLGFTLRGNAPVQVHFLDPYCSASVAGAREGDYIVSIQLVDCKW 568
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Match: RHPN1 (rhophilin Rho GTPase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19973]) HSP 1 Score: 233.032 bits (593), Expect = 3.966e-66 Identity = 163/578 (28.20%), Postives = 291/578 (50.35%), Query Frame = 1
Query: 139 RDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDT--YQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFX--XXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLH---LPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMK---IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLR-WSSQEVLVQITA 1836
R + + + Q Q +L R +I+++I+K+L+M++GA NL T + R++ + +E+ + SNL+L KEELE + +D + +PMIP+ +K T ++D+ + ++ H+GED Y I + + R+A++ P R+ G+ YYN + ++ RF P RS G+ F W D TGVP QQR FEK ++FN+GAL++Q+ + ++ G + F + F+ L NF + PS DM L L LM QA EC F +D + LR L E+ ++ + V+ ++ + +++P +W LV VK+ Y+++LA+ +A D + E + E L PT LP E L K + A+ EE+++L A+ + LR ++ L ++ + + + L++ + + + P++Q +T ++ + +SQ D F LGP+ +F+++ + +GP V + R + GFG T++G P+ + V S A +GLK GD+++S++ R W EV+ ++ A
Sbjct: 18 RLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLR---LAQEAAQVAAEYRLVHRTMAQPPVH--DYVPVSWTALVHVKAEYFRSLAHYHVAMALC------DGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQ--PKTHQKPEARMPR-LSQGKGPDIFHRLGPLSVFSAKNRWRLVGP---VHLTRGEG-GFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKA 577
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Match: PTPN23 (protein tyrosine phosphatase non-receptor type 23 [Source:HGNC Symbol;Acc:HGNC:14406]) HSP 1 Score: 89.3521 bits (220), Expect = 1.673e-17 Identity = 69/278 (24.82%), Postives = 131/278 (47.12%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKY---IEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQE 1218
+PMI + +K D F+ + + + +YGE+P+ Y ++ +EL+ R+ A++ PR EG Y +++++ R + + +W ++F+G +E++ I++NLGAL+S L + + ++ G++ S +F + F +L +F SVDM ++L + NLM QA EC + N ++ + S + ++ +L N + L I + W LVQ+K Y+ A+A +L M K Q+
Sbjct: 7 MPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELL--RQNAVRVPR-DFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVA---------HLHMGKQAEEQQ 264
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Match: PDCD6IP (programmed cell death 6 interacting protein [Source:HGNC Symbol;Acc:HGNC:8766]) HSP 1 Score: 80.1073 bits (196), Expect = 1.102e-15 Identity = 53/194 (27.32%), Postives = 92/194 (47.42%), Query Frame = 1
Query: 406 MIPIAMKNTVDIDFKNSFRNILENHY---GEDPDKYIEAIE-LVNSRRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-------TGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNP----PSVDMKPEMLQMLANLMRVQAME 939
I + +K T ++D ++ Y GE+ +Y A E L RR A+ P +EG ++ +L YY+ I IE +F F + + F+W D F V + +EKS ++FN AL SQ+A+ + GL+ + ++ + F H+ ++ P+VD+ P+ + L+ +M QA E
Sbjct: 4 FISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQE 197
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Match: PDCD6IP (programmed cell death 6 interacting protein [Source:HGNC Symbol;Acc:HGNC:8766]) HSP 1 Score: 78.1814 bits (191), Expect = 3.111e-14 Identity = 54/196 (27.55%), Postives = 93/196 (47.45%), Query Frame = 1
Query: 409 IPIAMKNTVDIDFKNSFRNILENHY---GEDPDKYIEAIE-LVNSRRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-------TGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNP----PSVDMKPEMLQMLANLMRVQAMECKF 948
I + +K T ++D ++ Y GE+ +Y A E L RR A+ P +EG ++ +L YY+ I IE +F F + + F+W D F V + +EKS ++FN AL SQ+A+ + GL+ + ++ + F H+ ++ P+VD+ P+ + L+ +M QA E F
Sbjct: 5 ISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFF 200
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Match: alx-1 (Apoptosis-linked gene 2-interacting protein X 1 [Source:UniProtKB/Swiss-Prot;Acc:P34552]) HSP 1 Score: 71.2478 bits (173), Expect = 1.866e-12 Identity = 64/261 (24.52%), Postives = 119/261 (45.59%), Query Frame = 1
Query: 421 MKNTVDIDFKNSFRNILENHYGEDPD---KYIEAIELVNS-RRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
+K+T ++D + ++N Y + EA++ +N R KA P ++ +D + YY+ + IE + N ++F W D F G F R S+ FE++ ++FN+G+L SQ+ + T ++ S F S F L + P+ D+ P+ L L+ LM QA E + +K +DK ++A +V S ++ + ++ ++++ L + W +V K+ Y+ALA
Sbjct: 11 LKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIY-----IKGHKDK---MKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWD--KDWSAIVSGKNLAYQALA 261
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Match: alx-1 (Apoptosis-linked gene 2-interacting protein X 1 [Source:UniProtKB/Swiss-Prot;Acc:P34552]) HSP 1 Score: 71.2478 bits (173), Expect = 2.069e-12 Identity = 64/261 (24.52%), Postives = 119/261 (45.59%), Query Frame = 1
Query: 421 MKNTVDIDFKNSFRNILENHYGEDPD---KYIEAIELVNS-RRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
+K+T ++D + ++N Y + EA++ +N R KA P ++ +D + YY+ + IE + N ++F W D F G F R S+ FE++ ++FN+G+L SQ+ + T ++ S F S F L + P+ D+ P+ L L+ LM QA E + +K +DK ++A +V S ++ + ++ ++++ L + W +V K+ Y+ALA
Sbjct: 11 LKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIY-----IKGHKDK---MKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWD--KDWSAIVSGKNLAYQALA 261
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Match: alx-1 (Apoptosis-linked gene 2-interacting protein X 1 [Source:UniProtKB/Swiss-Prot;Acc:P34552]) HSP 1 Score: 70.8626 bits (172), Expect = 2.550e-12 Identity = 64/261 (24.52%), Postives = 119/261 (45.59%), Query Frame = 1
Query: 421 MKNTVDIDFKNSFRNILENHYGEDPD---KYIEAIELVNS-RRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
+K+T ++D + ++N Y + EA++ +N R KA P ++ +D + YY+ + IE + N ++F W D F G F R S+ FE++ ++FN+G+L SQ+ + T ++ S F S F L + P+ D+ P+ L L+ LM QA E + +K +DK ++A +V S ++ + ++ ++++ L + W +V K+ Y+ALA
Sbjct: 11 LKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIY-----IKGHKDK---MKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWD--KDWSAIVSGKNLAYQALA 261
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Match: alx-1 (Apoptosis-linked gene 2-interacting protein X 1 [Source:UniProtKB/Swiss-Prot;Acc:P34552]) HSP 1 Score: 70.8626 bits (172), Expect = 2.550e-12 Identity = 64/261 (24.52%), Postives = 119/261 (45.59%), Query Frame = 1
Query: 421 MKNTVDIDFKNSFRNILENHYGEDPD---KYIEAIELVNS-RRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
+K+T ++D + ++N Y + EA++ +N R KA P ++ +D + YY+ + IE + N ++F W D F G F R S+ FE++ ++FN+G+L SQ+ + T ++ S F S F L + P+ D+ P+ L L+ LM QA E + +K +DK ++A +V S ++ + ++ ++++ L + W +V K+ Y+ALA
Sbjct: 11 LKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIY-----IKGHKDK---MKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWD--KDWSAIVSGKNLAYQALA 261
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Match: alx-1 (Apoptosis-linked gene 2-interacting protein X 1 [Source:UniProtKB/Swiss-Prot;Acc:P34552]) HSP 1 Score: 68.1662 bits (165), Expect = 1.054e-11 Identity = 64/261 (24.52%), Postives = 119/261 (45.59%), Query Frame = 1
Query: 421 MKNTVDIDFKNSFRNILENHYGEDPD---KYIEAIELVNS-RRKAIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
+K+T ++D + ++N Y + EA++ +N R KA P ++ +D + YY+ + IE + N ++F W D F G F R S+ FE++ ++FN+G+L SQ+ + T ++ S F S F L + P+ D+ P+ L L+ LM QA E + +K +DK ++A +V S ++ + ++ ++++ L + W +V K+ Y+ALA
Sbjct: 11 LKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIY-----IKGHKDK---MKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWD--KDWSAIVSGKNLAYQALA 261
BLAST of Rhophilin-2-like Protein vs. Ensembl Fly
Match: Rhp (gene:FBgn0026374 transcript:FBtr0074095) HSP 1 Score: 300.442 bits (768), Expect = 4.315e-91 Identity = 203/614 (33.06%), Postives = 315/614 (51.30%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRAL-ELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIY---LFMSKDVN-SQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLH------SLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKL---------------------------------GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC-SLIKLTVTT 1869
T RSKL R K+N++INK+LR+++GA NL + T +++++ + +E+ F SNL+L KE+L N +++ YQ +PMIP+ +K T +I+F F + + HY E+P YI+AI + R+A + P R G+ YYN + ++E+RFF PDR+ G+ F W D TGVP QRT FEK+ +FNLG +Y+Q+ + +TT+ GL+ + + FL + F H+ F N PS+D+KP++L +L +LM QA EC F +E + +A +L GE+ IS + ++ NI+ ++P+ W LV VK+ YKA A+ A L SK +QE+ S E+++ I Y +S A L+ L EAL IEE+ +L M ++L+N L+ + H ++L S E DLL E VEA + SL + + DPFK LGPI IF++R R V + + L FGF V+G P+ + +VE NS A+ G+K GDF++ + D++W S + +VQ+ C S ++L V T
Sbjct: 41 TCRSKLQNRRCKLNKEINKELRLRAGAENLYKATSNRKLRDTVALELSFVNSNLQLLKEQLAELNSSVEIYQSESHNGIMPMIPLGLKETKEINFMEPFSDFILEHYSEEPSMYIDAIADMTDTRQASKTPSRDALGVALLFRYYNTLYYVERRFFPPDRNLGVYFEWYDSLTGVPSCQRTIAFEKACTLFNLGGIYTQIGARHDRTTERGLDLAVDSFLRAAGVFRHIYDTFTNAPSMDLKPQVLDVLVSLMLSQARECLF--EKLQLQIEAMSHDCQAFRDLAGEAAQISHEYNEMHK--NIQANDTHTYLPECWAGLVPVKAELYKAFAHFYKARSIDATDELKASKSSQKNQESFIGNSQEVER-ITTADYGASDEASTSIANKLAHL--KEALASIEEAQRLQRMCRFLKNKASLTEVMKEVHSKSQEELEKFRLQASAKNIEDGDLL---ERSVEA-SSKFTLSLTGPDFTSHKVKDPFKRLGPIAIFSARRHWTAPRCVRLQKGSSLYHSVPSNDNKCPLDNDDDEEHDGGYNLYKEEFENFGFHVRGDAPVIIAHVEINSLADLGGIKEGDFIVEIAGVDVKWYSHQQVVQLIQSCGSTLELRVIT 643
BLAST of Rhophilin-2-like Protein vs. Ensembl Fly
Match: Rhp (gene:FBgn0026374 transcript:FBtr0074096) HSP 1 Score: 300.442 bits (768), Expect = 4.315e-91 Identity = 203/614 (33.06%), Postives = 315/614 (51.30%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRAL-ELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIY---LFMSKDVN-SQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLH------SLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKL---------------------------------GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC-SLIKLTVTT 1869
T RSKL R K+N++INK+LR+++GA NL + T +++++ + +E+ F SNL+L KE+L N +++ YQ +PMIP+ +K T +I+F F + + HY E+P YI+AI + R+A + P R G+ YYN + ++E+RFF PDR+ G+ F W D TGVP QRT FEK+ +FNLG +Y+Q+ + +TT+ GL+ + + FL + F H+ F N PS+D+KP++L +L +LM QA EC F +E + +A +L GE+ IS + ++ NI+ ++P+ W LV VK+ YKA A+ A L SK +QE+ S E+++ I Y +S A L+ L EAL IEE+ +L M ++L+N L+ + H ++L S E DLL E VEA + SL + + DPFK LGPI IF++R R V + + L FGF V+G P+ + +VE NS A+ G+K GDF++ + D++W S + +VQ+ C S ++L V T
Sbjct: 41 TCRSKLQNRRCKLNKEINKELRLRAGAENLYKATSNRKLRDTVALELSFVNSNLQLLKEQLAELNSSVEIYQSESHNGIMPMIPLGLKETKEINFMEPFSDFILEHYSEEPSMYIDAIADMTDTRQASKTPSRDALGVALLFRYYNTLYYVERRFFPPDRNLGVYFEWYDSLTGVPSCQRTIAFEKACTLFNLGGIYTQIGARHDRTTERGLDLAVDSFLRAAGVFRHIYDTFTNAPSMDLKPQVLDVLVSLMLSQARECLF--EKLQLQIEAMSHDCQAFRDLAGEAAQISHEYNEMHK--NIQANDTHTYLPECWAGLVPVKAELYKAFAHFYKARSIDATDELKASKSSQKNQESFIGNSQEVER-ITTADYGASDEASTSIANKLAHL--KEALASIEEAQRLQRMCRFLKNKASLTEVMKEVHSKSQEELEKFRLQASAKNIEDGDLL---ERSVEA-SSKFTLSLTGPDFTSHKVKDPFKRLGPIAIFSARRHWTAPRCVRLQKGSSLYHSVPSNDNKCPLDNDDDEEHDGGYNLYKEEFENFGFHVRGDAPVIIAHVEINSLADLGGIKEGDFIVEIAGVDVKWYSHQQVVQLIQSCGSTLELRVIT 643
BLAST of Rhophilin-2-like Protein vs. Ensembl Fly
Match: mop (gene:FBgn0036448 transcript:FBtr0075700) HSP 1 Score: 54.6842 bits (130), Expect = 3.779e-7 Identity = 39/185 (21.08%), Postives = 85/185 (45.95%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFS--WNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNF--VNPPSVDMKPEMLQMLANLMRVQAMEC 942
L M+ A+K++ + + + + Y EDP+ Y + + + + R + + ++ YY ++ ++ RF P ++ IF+ W D++ + FE++ ++FN+ AL++Q + ++ G++ + +F + + L + VN M PE+L + QA EC
Sbjct: 7 LHMLWFALKSSPEGTSFAALKKYIAEFYHEDPEAYSKEVHALETLRNQAMHTTKDGAPVMKR--YYCQLHALQNRF--PQLADRGIFTFKWKDLYHSAVHEVTDLRFERAAVLFNIAALHTQSGASVTRGDVDGMKMACTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQAQEC 187
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Match: rhpn1 (rhophilin, Rho GTPase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-081031-79]) HSP 1 Score: 278.1 bits (710), Expect = 4.430e-83 Identity = 186/606 (30.69%), Postives = 327/606 (53.96%), Query Frame = 1
Query: 160 IFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLI-----KPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC--SLIKLTVTTITEMGLTRNHTFSTSAPFDLNKSSQ 1944
+ TQRSKL + R K+N++IN++L ++SGA NL + ++++K + +E+ F SNL+L KEELE N +++ YQ L PMIP+ +K T +ID ++ + HYGED Y+ I+ R+A++ P R+ G + Y+N + +++RFF P RS G+ F W D TGVP QR FEK ++FN+GALY+Q+ + ++T +G+E++ + F + F +L NF + PS+DM L ML LM Q EC + L ++D N+ L+ E+ +S ++ V ++++ LL+ +++P +WI++VQVK+++++ALA+ A + L V ++ ED AE+K L+ +P K +L P K L K + +A+ EE+++L + K LR ++ L L++ H +++ +++ + + ++ PE+Q + I F+ + +D F LGP+ +F++R + R V ++R + G G T++G P+ V V A GL+ GD++++++ D RW+ +V C ++L + T+ + R S S D SQ
Sbjct: 28 LVSTQRSKLQQRRAKLNQQINRELLLRSGAENLYRASTNQKVKETVALELSFVNSNLQLLKEELEELNSSMNIYQTESETLNVPMIPLGLKETKEIDMTVPLQDFIAEHYGEDASLYLNEIQDFMELRQAMRTPSRNEAGQELLMEYFNQLYFLDQRFFSPHRSLGVHFHWYDSLTGVPSVQRALAFEKGSVLFNIGALYTQIGARQDRSTLSGIEDAIDAFQRAAGAFLYLQENFSHAPSLDMSGSALSMLVRLMVAQVQEC--VCEKVLLNIQDIHLNV-LLQAAQEAARVSDVYSLVLQAMSVPLLK--DYVPFSWISMVQVKTHHFRALAHYYTA---VALCDCSGVGDED--ED-GAEIKALVQIHTRQPEKLNLQDPEDKRR---LGKAHLRKAIIRHEEALRLHGVCKMLRKMDILQEVLSDAHTRSLEKYSDIDQEDDFCEVAEAPEVQSHTQQKPDIKAPDFSVVRV----TDIFHRLGPLSVFSARNRW-TRRHVCLVRGEA-GLGLTLRGDSPVLVAGVLPGGCA-AGGLREGDYIVAVNSVDCRWAEHAEVVHALKSCPDRGLELDIITLQTHEVERRMNLSPSGEQDYQSGSQ 612
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Match: rhpn1 (rhophilin, Rho GTPase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-081031-79]) HSP 1 Score: 276.559 bits (706), Expect = 1.363e-82 Identity = 178/581 (30.64%), Postives = 315/581 (54.22%), Query Frame = 1
Query: 160 IFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLI-----KPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTIT 1875
+ TQRSKL + R K+N++IN++L ++SGA NL + ++++K + +E+ F SNL+L KEELE N +++ YQ L PMIP+ +K T +ID ++ + HYGED Y+ I+ R+A++ P R+ G + Y+N + +++RFF P RS G+ F W D TGVP QR FEK ++FN+GALY+Q+ + ++T +G+E++ + F + F +L NF + PS+DM L ML LM Q EC + L ++D N+ L+ E+ +S ++ V ++++ LL+ +++P +WI++VQVK+++++ALA+ A V + + AE+K L+ +P K +L P K L K + +A+ EE+++L + K LR ++ L L++ H +++ +++ + + ++ PE+Q + I F+ + +D F LGP+ +F++R + R V ++R + G G T++G P+ V V A + GL+ GD++++++ D RW+ +V C L + IT
Sbjct: 28 LVSTQRSKLQQRRAKLNQQINRELLLRSGAENLYRASTNQKVKETVALELSFVNSNLQLLKEELEELNSSMNIYQTESETLNVPMIPLGLKETKEIDMTVPLQDFIAEHYGEDASLYLNEIQDFMELRQAMRTPSRNEAGQELLMEYFNQLYFLDQRFFSPHRSLGVHFHWYDSLTGVPSVQRALAFEKGSVLFNIGALYTQIGARQDRSTLSGIEDAIDAFQRAAGAFLYLQENFSHAPSLDMSGSALSMLVRLMVAQVQEC--VCEKVLLNIQDIHLNV-LLQAAQEAARVSDVYSLVLQAMSVPLLK--DYVPFSWISMVQVKTHHFRALAHYYTA-----------VALCDCSGNYGAEIKALVQIHTRQPEKLNLQDPEDKRR---LGKAHLRKAIIRHEEALRLHGVCKMLRKMDILQEVLSDAHTRSLEKYSDIDQEDDFCEVAEAPEVQSHTQQKPDIKAPDFSVVRV----TDIFHRLGPLSVFSARNRW-TRRHVCLVRGEA-GLGLTLRGDSPVLVAGVLPGGCAAEGGLREGDYIVAVNSVDCRWAEHAEVVHALKSCPDRGLELDIIT 583
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:321330]) HSP 1 Score: 261.922 bits (668), Expect = 8.252e-77 Identity = 166/563 (29.48%), Postives = 297/563 (52.75%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLK--TGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-------DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMK-IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N QT RSKL R +N+KI K +RM++GA NL++ T + +++ ++ +E+ + S+L+L E+LE N +++ YQ+++ + +P+IP+ +K T D+DF ++ + HY ED + I+ + R+A + P R+N G+ Y++ ++ +E RFF P R GI F+W D FTG+P Q EK+ ++FN+ ALYSQ+ + + T AGLE++ F S + L F + PS DM P ML ML LM QA EC F + + + F L++ E+ ++ + V+ S+ IE +++P W + Q+K N+Y +LA+ ++ + L S D + QE A+ L + + P L + +K E + K + ++ EE+I+ ++L+ L+ LS+ L + + +K + + D++S E + E + T D F+ LGP+ +F+++ + P I +I++D+ L GFT+KG P+++ +++ A GLK GD+++++ D D +W
Sbjct: 26 NPFAQTGRSKLQNKRAVLNQKIIKQMRMRAGAENLLKATSNNKVREQVVLELSYVNSDLQLLMEQLEGLNSSVEVYQNVQESSSIPLIPLGLKETKDVDFSVPLKDFILEHYSEDGSNFQNQIDDLMDLRQACRTPSRNNSGVDLIANYFSQLSFLETRFFSPTRQIGIFFTWYDSFTGMPVCQNNISLEKASMLFNMAALYSQIGTRADRQTLAGLEDAIAAFQKSAGVLHLLKETFTHTPSYDMSPAMLSMLFRLMLAQAQECLFEQITLPGIRNEFFC---LLKMAQEAAKVAETYAQVHQSM-IE-TPITKNVPFFWTTMSQLKINHYNSLAHYFVSTALLDHQLNPSDDEDKQEKALSQLYDAMPEGRSP----LDILKNKDERRRIGKAHLQRSIMGHEEAIRTHCRCRHLQKLDILSDILRASLNRSLTKFEQNDKEDEFTDYMLAPDIISKTEKKAEMEIPAATKVKVT---------DLFQRLGPLSVFSAKQRWTAPRTIRLILQDRDL--GFTLKGDAPVQIQSLDPLCPAAAGGLKEGDYLVAVGDTDCKW 568
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Match: ptpn23a (protein tyrosine phosphatase, non-receptor type 23, a [Source:ZFIN;Acc:ZDB-GENE-100921-24]) HSP 1 Score: 103.99 bits (258), Expect = 2.811e-22 Identity = 81/309 (26.21%), Postives = 142/309 (45.95%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFP-DRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQ----EAIEDLSAELKQLIKPTKYHLHLPSSKLEAL 1308
+PMI + +K + F + + + +YGEDPD Y E ++ + R++ R EG Y+ +++++ R + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F +L +F + SVDM ++L + NLM QA EC L + N ++ + S + ++ +L N E L I + W LVQ+K Y+ A+A +L M K Q E + L + L +L + K P S EAL
Sbjct: 7 MPMIWLDLKEAGEFQFSPTVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGLGQEAAVPISWTEIFSGKTVTHEDICYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFAYLRDHFSHSYSVDMSHQILNLNINLMLGQAQEC--------LLEKSMLDNRKSFLVARISAQVVDYYKEACRALENSETASMLGKIQKDWKKLVQMKIYYFAAIA---------HLHMGKQAEEQQKYGERVAYLQSSLDKLGEAIKLAKGQPDSVQEAL 298
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Match: ptpn23a (protein tyrosine phosphatase, non-receptor type 23, a [Source:ZFIN;Acc:ZDB-GENE-100921-24]) HSP 1 Score: 99.7525 bits (247), Expect = 5.813e-21 Identity = 66/255 (25.88%), Postives = 123/255 (48.24%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFP-DRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAY 1158
+PMI + +K + F + + + +YGEDPD Y E ++ + R++ R EG Y+ +++++ R + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F +L +F + SVDM ++L + NLM QA EC + N ++ + S + ++ +L N E L I + W LVQ+K Y+ A+A+
Sbjct: 7 MPMIWLDLKEAGEFQFSPTVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGLGQEAAVPISWTEIFSGKTVTHEDICYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFAYLRDHFSHSYSVDMSHQILNLNINLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENSETASMLGKIQKDWKKLVQMKIYYFAAIAH 253
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:100145690]) HSP 1 Score: 303.523 bits (776), Expect = 2.661e-92 Identity = 187/570 (32.81%), Postives = 317/570 (55.61%), Query Frame = 1
Query: 124 LAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
L+ +N RK I QT RSKL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R GI + Y+ + +E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEES F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L++ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKAL +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L N L+ H+ + + KH+ + DLLS P++ + E + +I L S+ +D F+ LGP+ +F+ + + R V I ++ FGF +KG P++VV+++ + GLK GD+++S++ D +W S
Sbjct: 15 LSEQNYFRKGKSIAQTGRSKLQNQRASLNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGIELLMSYFQQLGFLENRFFPPSRNMGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEESVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKVAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALTNYFVAVILIDYQLNLSDDEDKQEKAIAQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRCHEEAIRFSTLCSTLRQIDVLQNILSAFHQRSLLKFSQHQKHDDFLDLLSAPDIVSKTEYQAEMIPPQL-----SRVKATDLFQRLGPLSVFSVKQRWSAPRKVCITKEDG-DFGFLLKGDSPVQVVSLDPLCPSATEGLKEGDYIVSVEGEDCKWCS 569
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:100145690]) HSP 1 Score: 298.901 bits (764), Expect = 1.102e-90 Identity = 183/563 (32.50%), Postives = 312/563 (55.42%), Query Frame = 1
Query: 145 RKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
+ I QT RSKL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R GI + Y+ + +E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEES F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L++ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKAL +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L N L+ H+ + + KH+ + DLLS P++ + E + +I L S+ +D F+ LGP+ +F+ + + R V I ++ FGF +KG P++VV+++ + GLK GD+++S++ D +W S
Sbjct: 2 KSGKSIAQTGRSKLQNQRASLNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGIELLMSYFQQLGFLENRFFPPSRNMGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEESVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKVAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALTNYFVAVILIDYQLNLSDDEDKQEKAIAQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRCHEEAIRFSTLCSTLRQIDVLQNILSAFHQRSLLKFSQHQKHDDFLDLLSAPDIVSKTEYQAEMIPPQL-----SRVKATDLFQRLGPLSVFSVKQRWSAPRKVCITKEDG-DFGFLLKGDSPVQVVSLDPLCPSAVKGLKEGDYIVSVEGEDCKWCS 549
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:100145690]) HSP 1 Score: 298.516 bits (763), Expect = 2.505e-90 Identity = 183/558 (32.80%), Postives = 311/558 (55.73%), Query Frame = 1
Query: 160 IFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
I QT RSKL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R GI + Y+ + +E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEES F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L++ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKAL +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L N L+ H+ + + KH+ + DLLS P++ + E + +I L S+ +D F+ LGP+ +F+ + + R V I ++ FGF +KG P++VV+++ + GLK GD+++S++ D +W S
Sbjct: 34 IAQTGRSKLQNQRASLNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGIELLMSYFQQLGFLENRFFPPSRNMGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEESVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKVAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALTNYFVAVILIDYQLNLSDDEDKQEKAIAQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRCHEEAIRFSTLCSTLRQIDVLQNILSAFHQRSLLKFSQHQKHDDFLDLLSAPDIVSKTEYQAEMIPPQL-----SRVKATDLFQRLGPLSVFSVKQRWSAPRKVCITKEDG-DFGFLLKGDSPVQVVSLDPLCPSAVKGLKEGDYIVSVEGEDCKWCS 576
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:100145690]) HSP 1 Score: 290.041 bits (741), Expect = 1.535e-87 Identity = 178/551 (32.30%), Postives = 306/551 (55.54%), Query Frame = 1
Query: 181 KLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
KL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R GI + Y+ + +E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEES F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L++ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKAL +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L N L+ H+ + + KH+ + DLLS P++ + E + +I L S+ +D F+ LGP+ +F+ + + R V I ++ FGF +KG P++VV+++ + GLK GD+++S++ D +W S
Sbjct: 7 KLQNQRASLNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGIELLMSYFQQLGFLENRFFPPSRNMGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEESVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKVAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALTNYFVAVILIDYQLNLSDDEDKQEKAIAQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRCHEEAIRFSTLCSTLRQIDVLQNILSAFHQRSLLKFSQHQKHDDFLDLLSAPDIVSKTEYQAEMIPPQL-----SRVKATDLFQRLGPLSVFSVKQRWSAPRKVCITKEDG-DFGFLLKGDSPVQVVSLDPLCPSAVKGLKEGDYIVSVEGEDCKWCS 542
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Match: rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:NCBI gene;Acc:100145690]) HSP 1 Score: 290.812 bits (743), Expect = 2.217e-87 Identity = 182/573 (31.76%), Postives = 312/573 (54.45%), Query Frame = 1
Query: 124 LAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSL-----GPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
L+ +N RK I QT RSKL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R GI + Y+ + +E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEES F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L++ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKAL +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L N L+ H+ + + KH+ + DLLS P++ + + +++S + F GP+ +F+ + + R V I ++ FGF +KG P++VV+++ + GLK GD+++S++ D +W S
Sbjct: 15 LSEQNYFRKGKSIAQTGRSKLQNQRASLNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGIELLMSYFQQLGFLENRFFPPSRNMGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEESVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKVAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALTNYFVAVILIDYQLNLSDDEDKQEKAIAQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRCHEEAIRFSTLCSTLRQIDVLQNILSAFHQRSLLKFSQHQKHDDFLDLLSAPDIVSKYGLPLFLLLCIHELLSNISKWTYFTYFTFNVQGPLSVFSVKQRWSAPRKVCITKEDG-DFGFLLKGDSPVQVVSLDPLCPSAVKGLKEGDYIVSVEGEDCKWCS 577
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Match: Rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:MGI Symbol;Acc:MGI:1289234]) HSP 1 Score: 270.396 bits (690), Expect = 5.169e-80 Identity = 165/559 (29.52%), Postives = 304/559 (54.38%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLS---CPELQVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL+++ +++++ ++ +E+ F S+L++ KEELE N ++ YQ + +P+IP+ +K T ++DF F++ + HY ED Y + I + R+A + P R G+ + Y+ + +E RFF P R G++F+W D FTGVP Q+T + EK+ ++FN+GALY+Q+ + ++ TQAGLE + + F + N+L F + PS DM P ML +L +M QA E F + + + F ++ + E+ ++ + ++++++ E ++ E+IP +W ++ VK+ +Y ALA+ A I L D + QE + L + + + P L + + + L K ++ A+ EES++ A + K LR++ L + L+ H+ QL E DLL+ P++ + V I F+++ +D F+ LGP+ +F++ + P R + ++ GFT++G P++V ++ + +A +G K GD+++S+ D +W
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASVLFNIGALYTQIGTRCNRQTQAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKVCLPGIQNEFFVLVKVAQ---EAAKVAEAYRQLHAAMSQEPVK--ENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTP----LATLKNAGQRVLLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQR--TQLKHTQHREDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTV----TDFFQKLGPLSVFSASKRWSPPRGIHFTVEEG-DLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGVDCKW 568
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Match: Rhpn2 (rhophilin, Rho GTPase binding protein 2 [Source:MGI Symbol;Acc:MGI:1289234]) HSP 1 Score: 270.396 bits (690), Expect = 5.169e-80 Identity = 165/559 (29.52%), Postives = 304/559 (54.38%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLS---CPELQVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL+++ +++++ ++ +E+ F S+L++ KEELE N ++ YQ + +P+IP+ +K T ++DF F++ + HY ED Y + I + R+A + P R G+ + Y+ + +E RFF P R G++F+W D FTGVP Q+T + EK+ ++FN+GALY+Q+ + ++ TQAGLE + + F + N+L F + PS DM P ML +L +M QA E F + + + F ++ + E+ ++ + ++++++ E ++ E+IP +W ++ VK+ +Y ALA+ A I L D + QE + L + + + P L + + + L K ++ A+ EES++ A + K LR++ L + L+ H+ QL E DLL+ P++ + V I F+++ +D F+ LGP+ +F++ + P R + ++ GFT++G P++V ++ + +A +G K GD+++S+ D +W
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASVLFNIGALYTQIGTRCNRQTQAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKVCLPGIQNEFFVLVKVAQ---EAAKVAEAYRQLHAAMSQEPVK--ENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTP----LATLKNAGQRVLLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQR--TQLKHTQHREDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTV----TDFFQKLGPLSVFSASKRWSPPRGIHFTVEEG-DLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGVDCKW 568
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Match: Rhpn1 (rhophilin, Rho GTPase binding protein 1 [Source:MGI Symbol;Acc:MGI:1098783]) HSP 1 Score: 249.21 bits (635), Expect = 2.363e-72 Identity = 162/571 (28.37%), Postives = 288/571 (50.44%), Query Frame = 1
Query: 145 RKNNRIF-QTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSK-DVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHES-YDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMK---IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQ-EVLVQI 1830
RK F Q Q +L +R +++++I+K+LRM++GA NL T + ++ + +E+ + SNL+L KEEL + ++D Q G+ PMIP+ +K T ++D+ + ++ H+GED + I+ + R+A + P R G+ YY+ + ++ RFF P RS G++F W D TGVP QQR FEK ++FN+GAL++Q+ + + G + F + F L NF + PS DM L ML LM QA EC F LL + L+L E+ ++ + V+ ++ ++ +++P +W NL VK+ ++ ALA+ A +K ++ QE + S + L PT LP + L+K + A+ EE+++L + + LR ++ L + + + + L + + ++ P++Q + + +SQ +D F LGP+ +F+++ + +GP V + R + FGFT++G P+ + V AE +GLK GD+++S++ +W EV+ Q+
Sbjct: 26 RKGYGSFVQNQPGQLQSHRARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSTSVDVDQPEGEGITIPMIPLGLKETKELDWATPLKELISEHFGEDGTSFETEIQELEDLRQATRTPSRDEAGLDLLAAYYSQLCFLDARFFSPSRSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTNHAAEAFQRAAGAFRLLRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDQ-LQLAQEAAQVATEYGLVHRAMAQPPVR--DYLPASWTNLAHVKAEHFCALAHYHAAMALCESHPAKGELARQEHVFQPSTPHEPL-GPT-----LPQHPEDRRKLAKAHLKRAILGQEEALRLHTLCRVLRKVDLLQVVVTQALRRSLAKYSQLEREDDFFEATEAPDIQPKTHQ---TPEVRMPSLSQVKVTDFFHRLGPLSVFSTKNRWQLVGP---VHMTRGEG-SFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQL 580
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Match: Rhpn1 (rhophilin, Rho GTPase binding protein 1 [Source:MGI Symbol;Acc:MGI:1098783]) HSP 1 Score: 243.047 bits (619), Expect = 3.516e-70 Identity = 160/571 (28.02%), Postives = 283/571 (49.56%), Query Frame = 1
Query: 145 RKNNRIF-QTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSK-DVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHES-YDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMK---IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQ-EVLVQI 1830
RK F Q Q +L +R +++++I+K+LRM++GA NL T + ++ + +E+ + SNL+L KEEL + ++D Q G+ PMIP+ +K T ++D+ + ++ H+GED + I+ + R+A + P R G+ YY+ + ++ RFF P RS G++F W D TGVP QQR FEK ++FN+GAL++Q+ + + G + F + F L NF + PS DM L ML LM QA EC F LL + L+L E+ ++ + V+ ++ ++ +++P +W NL VK+ ++ ALA+ A +K ++ QE + S + L PT LP + L+K + A+ EE+++L + + LR ++ L + + + + L + + ++ P++Q + Q PE GP+ +F+++ + +GP V + R + FGFT++G P+ + V AE +GLK GD+++S++ +W EV+ Q+
Sbjct: 26 RKGYGSFVQNQPGQLQSHRARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSTSVDVDQPEGEGITIPMIPLGLKETKELDWATPLKELISEHFGEDGTSFETEIQELEDLRQATRTPSRDEAGLDLLAAYYSQLCFLDARFFSPSRSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTNHAAEAFQRAAGAFRLLRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDQ-LQLAQEAAQVATEYGLVHRAMAQPPVR--DYLPASWTNLAHVKAEHFCALAHYHAAMALCESHPAKGELARQEHVFQPSTPHEPL-GPT-----LPQHPEDRRKLAKAHLKRAILGQEEALRLHTLCRVLRKVDLLQVVVTQALRRSLAKYSQLEREDDFFEATEAPDIQPKTH--------------QTPE-------GPLSVFSTKNRWQLVGP---VHMTRGEG-SFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQL 562
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Match: Rhpn1 (rhophilin, Rho GTPase binding protein 1 [Source:MGI Symbol;Acc:MGI:1098783]) HSP 1 Score: 203.371 bits (516), Expect = 1.624e-57 Identity = 109/341 (31.96%), Postives = 183/341 (53.67%), Query Frame = 1
Query: 145 RKNNRIF-QTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAY 1158
RK F Q Q +L +R +++++I+K+LRM++GA NL T + ++ + +E+ + SNL+L KEEL + ++D Q G+ PMIP+ +K T ++D+ + ++ H+GED + I+ + R+A + P R G+ YY+ + ++ RFF P RS G++F W D TGVP QQR FEK ++FN+GAL++Q+ + + G + F + F L NF + PS DM L ML LM QA EC F LL + L+L E+ ++ + V+ ++ ++ +++P +W NL VK+ ++ ALA+
Sbjct: 26 RKGYGSFVQNQPGQLQSHRARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSTSVDVDQPEGEGITIPMIPLGLKETKELDWATPLKELISEHFGEDGTSFETEIQELEDLRQATRTPSRDEAGLDLLAAYYSQLCFLDARFFSPSRSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTNHAAEAFQRAAGAFRLLRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDQ-LQLAQEAAQVATEYGLVHRAMAQPPVR--DYLPASWTNLAHVKAEHFCALAH 363
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Match: sp|Q63ZR5|RHN2B_XENLA (Rhophilin-2-B OS=Xenopus laevis OX=8355 GN=rhpn2-b PE=2 SV=1) HSP 1 Score: 296.204 bits (757), Expect = 7.941e-89 Identity = 184/568 (32.39%), Postives = 317/568 (55.81%), Query Frame = 1
Query: 124 LAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSS 1809
L+ +N RK I QT RSKL R +N++I K +RM++GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R G+ + Y+ + ++E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALYSQ+ + ++ T+ GLEE+ F + N+L F + PS DM P ML L ++ +A EC F + L ++++F L L+ E+ +S + VY+ +N ++ E++P +W +VQVK+ +YKALA +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L L+ H+ + + K + + DLLS P+ + ++T +++ Q +S++ +D F+ LGP+ IF+ + + R + I ++ FGF +KG P++V++++ A GLK GD+++S+ D +W S
Sbjct: 15 LSEQNYFRKGKSIAQTGRSKLQNQRAILNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGVELLVSYFQQLGYLENRFFPPSRNIGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYSQIGTRCNRQTKIGLEEAVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGALIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKAAQEAAKVSEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALANYFVAITLIDYQLNLSDDEDKQEKAISQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRSHEEAIRFSTLCSTLRQIDVLQLILSAFHQRSLLKFSQHQKPDDFLDLLSAPD--IVSKTEYQAETIPPQ-LSKDKVTDIFQRLGPLSIFSVKQRWSAPRKMCITKEDG-DFGFVLKGDCPVQVISLDPLCPAATEGLKEGDYIVSVAGKDCKWCS 569
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Match: sp|Q6DJJ6|RHN2A_XENLA (Rhophilin-2-A OS=Xenopus laevis OX=8355 GN=rhpn2-a PE=2 SV=1) HSP 1 Score: 295.819 bits (756), Expect = 1.323e-88 Identity = 188/596 (31.54%), Postives = 326/596 (54.70%), Query Frame = 1
Query: 124 LAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLK--TGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEV---LVQITAKCSLIKLTVTTITE 1878
L+ +N RK I QT RSKL R +N++I K +RM+ GA NL+ T + +I+ ++ +E+ F SNL+ KEELER N +++ YQ + + +P+IP+ +K T D+DF +F++ + HY ED +Y + + R+A + P R G+ + Y+ + ++E RFF P R+ GI+F+W D FTGVP Q EK+ I+FN+ ALY+Q+ + ++ T+ GLEE+ F + N+L F + PS DM P ML +L ++ +A EC F + L ++++F L L+ E+ + + VY+ +N ++ E++P +W +VQVK+ +YKALA +A I L +S D + QE AI L + + + L + L L K +++A+ EE+I+ + + LR ++ L L+ H+ + K + + DLLS P++ + E + I+ L S++ +D F+ LGP+ +F+ + + R + I ++ FGF ++G P++V++++ A GLK GD+++S+ D +W S ++Q T K S I++ V +I +
Sbjct: 15 LSEQNYFRKGKSIAQTGRSKLQNQRASLNQQILKAMRMRVGAENLLRATSNNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQDSNIPLIPLGLKETKDVDFTTAFKDFISEHYSEDASEYENELADLMDLRQACRTPSRDEAGVELLVSYFQQLGYLENRFFPPSRNLGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYTQIGTRCNRQTKIGLEEAVTAFQKATGVLNYLKETFTHTPSYDMSPAMLGVLIKMLLAEAHECYF-EKMILSGIQNEFCTL--LKAAQEAAKVGEVHMQVYTLMNQAPIK--ENVPYSWSVMVQVKAEHYKALANYFVAIILIDYQLSLSDDEDKQEKAISQLYDSMPEGLTAQTI---LKDQQQRTL-LGKAHLSKAIRSHEEAIRFSTLCSTLRQIDVLQKILSAFHQRSQLKFSQHQKPDDFLDLLSAPDIVSKTEYQAKTISPQL-----SKDKVTDIFQRLGPLSVFSVKQRWSAPRKICITKEDG-DFGFVLRGDCPVQVISLDPLCPAATEGLKEGDYIVSVAGKDCKWCSTSQVMDMLQATGKQS-IEIQVISIQD 594
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Match: sp|A4FUC9|RHPN2_BOVIN (Rhophilin-2 OS=Bos taurus OX=9913 GN=RHPN2 PE=2 SV=1) HSP 1 Score: 277.715 bits (709), Expect = 7.796e-82 Identity = 173/564 (30.67%), Postives = 316/564 (56.03%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKP--TKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEH-KSWI--DQLHS----LNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL++ +++++ ++ +E+ F S+L++ KEELE N ++ YQ+ + +P+IP+ +K T D+DF + ++ + HY ED Y + I + R+A + P R+ G+ + Y+ + +E RFF P R GI+F+W D TGVP Q+ + EK+ I+FN+GALY+Q+ + ++ T+AGLE + + F + N+L F + PS DM P ML +L +M QA E F + L + F ++ + E+ + ++ +++++N E ++ E+IP +W +L VK+++Y+ALA+ A I L +D + QE + L + + + + P T ++H + + LG S L +A+ EES++ A++ K LRN++ L L+ H +S + QL LN ++ D++S E +VE ++ Q F+++ +D F+ LGP+ +F++ + R + ++ GFT++G P++V ++ +A +G K GD+++S+ D D +W
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAMRMRTGAENLLKAATNQKVREQVRLELSFLNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFSVALKDFILEHYSEDSYLYEDEIADLMDLRQACRTPSRNEAGVELLMSYFMQLGFVESRFFPPTRQMGILFTWYDSLTGVPVSQQNLLLEKASILFNIGALYTQIGTRCNRQTEAGLESTVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESTFEKVCLPGLQNEFFLLVKVAQ---EAAKVGEVYRQLHTAMNQEPVK--ENIPYSWASLACVKAHHYEALAHYFTATLLIDHQLKPGEDEDHQEKCLSQLYSHMPEGLTPLATLKNVH----QRQLLGKSHLC--QAVTHHEESMREASLCKKLRNIDVLQEVLSAAHDRSQLKYTQLREDDDLLNLTDAPDIVSKTEREVEI---IVPQ--FSKVTV----TDFFQKLGPLSVFSANKRWTAPRSIHFTAEEG-DLGFTLRGNSPVQVHFLDPYCSAAAAGTKEGDYIVSIQDVDCKW 568
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Match: sp|Q8BWR8|RHPN2_MOUSE (Rhophilin-2 OS=Mus musculus OX=10090 GN=Rhpn2 PE=1 SV=2) HSP 1 Score: 270.396 bits (690), Expect = 3.615e-79 Identity = 165/559 (29.52%), Postives = 304/559 (54.38%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLS---CPELQVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL+++ +++++ ++ +E+ F S+L++ KEELE N ++ YQ + +P+IP+ +K T ++DF F++ + HY ED Y + I + R+A + P R G+ + Y+ + +E RFF P R G++F+W D FTGVP Q+T + EK+ ++FN+GALY+Q+ + ++ TQAGLE + + F + N+L F + PS DM P ML +L +M QA E F + + + F ++ + E+ ++ + ++++++ E ++ E+IP +W ++ VK+ +Y ALA+ A I L D + QE + L + + + P L + + + L K ++ A+ EES++ A + K LR++ L + L+ H+ QL E DLL+ P++ + V I F+++ +D F+ LGP+ +F++ + P R + ++ GFT++G P++V ++ + +A +G K GD+++S+ D +W
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASVLFNIGALYTQIGTRCNRQTQAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKVCLPGIQNEFFVLVKVAQ---EAAKVAEAYRQLHAAMSQEPVK--ENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTP----LATLKNAGQRVLLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQR--TQLKHTQHREDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTV----TDFFQKLGPLSVFSASKRWSPPRGIHFTVEEG-DLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGVDCKW 568
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Match: sp|Q8HXG3|RHPN2_CANLF (Rhophilin-2 OS=Canis lupus familiaris OX=9615 GN=RHPN2 PE=2 SV=1) HSP 1 Score: 270.011 bits (689), Expect = 6.638e-79 Identity = 170/576 (29.51%), Postives = 312/576 (54.17%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEH-KSWIDQLH------SLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCS 1845
N + QT RSKL R +N++I K +RM++GA NL+++ + +++ ++ +E+ F S+L++ KEELE N ++ YQ + +P+IP+ +K T DIDF ++ + HY ED Y + I + R+A + P R G+ + Y+ + +E RFF P R GI+F+W D TGVP Q+ + EK+ I+FN+GALY+Q+ + ++ TQAGL+ + + F + +HL F + PS DM P ML +L +M QA E F + + + F ++ + E+ + ++ ++++++ ++ E+IP +W +LV VK+++Y ALA+ A I L D + QE + L + + + P L S + L K + A+ EES++ A++ K LRN+ L + L+ H +S + LN ++ D++S E +VE ++ Q F+++ + +D F+ LGP+ +F++ + P R + ++ GFT++G P++V ++ + +A +G K GD+++S+ D D +W + ++++ C
Sbjct: 26 NPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNHKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQSTEEAFTVPLIPLGLKETKDIDFSVVLKDFILEHYSEDSYLYEDEIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRQMGILFTWYDSLTGVPVSQQNLLLEKASILFNIGALYTQIGTRCNRRTQAGLDGAVDAFQRAAGVLHHLKETFTHTPSYDMSPAMLSVLVKMMLAQAQENVFEKICLPGIRNEFFVLVKVAQ---EAAKVGEVYRQLHTAMSQAPVK--ENIPYSWASLVCVKAHHYAALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDHMPEGLTP----LATLKSGHQRRQLGKSHLRRAVAHHEESVREASLCKKLRNIEVLQDVLSVAHERSRLKYAQHQDDDDLLNLIDAPDIISKTEQEVEI---ILPQ--FSKVTA----TDFFQKLGPLSVFSANKRWTPPRSIHFTAEEG-DLGFTLRGNSPVQVHFLDPHCSAALAGAKEGDYIVSIQDVDCKWLTVSEVMKLLKACG 582
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Match: A0A139WFV4 (Rhophilin-2-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC033522 PE=4 SV=1) HSP 1 Score: 347.051 bits (889), Expect = 7.810e-106 Identity = 207/588 (35.20%), Postives = 335/588 (56.97%), Query Frame = 1
Query: 85 MNSSSKMSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSK-DVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHES--YDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKL-GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQI 1830
M S E F L + R ++ T R KL R K+N++INK+LR+++GA NL + T ++++K + +E+ F SNL+L KE+L N +++ YQ T +PMIP+ +K T +IDF++ F++ + HY ED ++Y +AI R+AI+ P R GI YYN + +E+RFF PDRS GI F W D TGVP QRT FEK+ ++FN+GA+Y+Q+ + ++T GL+ + + FL + F +++ NF N PS+D+ PEML+ML LM QA EC L L L+ E + ++ L+L E+ ++ + VY + E + +++P +WI+LVQVK YY +A+ +A+ ++ +K ++ ++ L AE T+ + LP E L + + E+L L EE +L M + LR L+ L N HK+ + Q ++ N++E D+L P +Q + +L +Q +D F++LGPI IF+++ R+V + R + GFGF+V+G P+ V VE NS AE G+K GDF++++ D D++WSS + +V +
Sbjct: 1 MCESDLRIEDFSDLPKKPFVRGSDPRVATCRGKLQNRRSKLNQEINKELRLRAGAENLFKATTNRKLKETVALELSFVNSNLQLLKEQLAELNSSVELYQSDSTDAVMPMIPLGLKETKEIDFRDPFKDFILEHYSEDANQYEDAIADFMDTRQAIRTPLRDTTGISLLFRYYNQLYFVERRFFPPDRSLGIYFEWFDSLTGVPSCQRTVAFEKACVLFNMGAIYTQIGAKQDRSTAKGLDAAVDSFLRAAGTFRYIHENFTNAPSMDLGPEMLEMLVQLMLAQAREC-LLEKLDLQSKESRSIDI-CLDLAQEAAHLADCYSQVYQLIMTESVH--DYVPYSWISLVQVKKEYYTGMAHYHVASGVLHKEAAKMSPTTKTTLQFLHAE----TASTQLDIRLPKDDAERRLLGRAHLRESLVLHEECQRLHRMCRELRGKQALTAVLRNAHKTAL-QAYTNNENEDDFSDVLDPPRVQAATK---FQLALTPPDFAQYRVNDLFRALGPIAIFSAKRHWTAPRLVQLHRGRTSEGFGFSVRGDAPVIVAIVESNSLAEFGGVKEGDFIVAISDKDVKWSSHDEVVAL 576
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Match: A0A139WFS4 (Rhophilin-2-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC033522 PE=4 SV=1) HSP 1 Score: 346.665 bits (888), Expect = 1.333e-105 Identity = 201/560 (35.89%), Postives = 326/560 (58.21%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSK-DVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHES--YDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKL-GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQI 1830
T R KL R K+N++INK+LR+++GA NL + T ++++K + +E+ F SNL+L KE+L N +++ YQ T +PMIP+ +K T +IDF++ F++ + HY ED ++Y +AI R+AI+ P R GI YYN + +E+RFF PDRS GI F W D TGVP QRT FEK+ ++FN+GA+Y+Q+ + ++T GL+ + + FL + F +++ NF N PS+D+ PEML+ML LM QA EC L L L+ E + ++ L+L E+ ++ + VY + E + +++P +WI+LVQVK YY +A+ +A+ ++ +K ++ ++ L AE T+ + LP E L + + E+L L EE +L M + LR L+ L N HK+ + Q ++ N++E D+L P +Q + +L +Q +D F++LGPI IF+++ R+V + R + GFGF+V+G P+ V VE NS AE G+K GDF++++ D D++WSS + +V +
Sbjct: 30 TCRGKLQNRRSKLNQEINKELRLRAGAENLFKATTNRKLKETVALELSFVNSNLQLLKEQLAELNSSVELYQSDSTDAVMPMIPLGLKETKEIDFRDPFKDFILEHYSEDANQYEDAIADFMDTRQAIRTPLRDTTGISLLFRYYNQLYFVERRFFPPDRSLGIYFEWFDSLTGVPSCQRTVAFEKACVLFNMGAIYTQIGAKQDRSTAKGLDAAVDSFLRAAGTFRYIHENFTNAPSMDLGPEMLEMLVQLMLAQAREC-LLEKLDLQSKESRSIDI-CLDLAQEAAHLADCYSQVYQLIMTESVH--DYVPYSWISLVQVKKEYYTGMAHYHVASGVLHKEAAKMSPTTKTTLQFLHAE----TASTQLDIRLPKDDAERRLLGRAHLRESLVLHEECQRLHRMCRELRGKQALTAVLRNAHKTAL-QAYTNNENEDDFSDVLDPPRVQAATK---FQLALTPPDFAQYRVNDLFRALGPIAIFSAKRHWTAPRLVQLHRGRTSEGFGFSVRGDAPVIVAIVESNSLAEFGGVKEGDFIVAISDKDVKWSSHDEVVAL 577
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Match: A0A1Y1L5A0 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_02495 PE=4 SV=1) HSP 1 Score: 344.739 bits (883), Expect = 6.381e-105 Identity = 199/566 (35.16%), Postives = 330/566 (58.30%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQD--LKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIK-------PTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHES--YDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKL-GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQI 1830
T R KL R K+N++INK+LR+++GA NL + T +++++ + +E+ F SNL+L KE+L N +++ YQ + + +PMIP+ +K T +IDF + F++ + HY ED +Y + I R+A++ P R N GI YYN + +E+RFF PDRS GI F W D TGVP QRT FEK+ ++FN+GA+Y+Q+ + + T GL+ + + FL + F +++ NF N PS+D+ PEML+ML LM QA EC L L+L+ ED+ ++ + +L E+ +S + NV+ + E ++ +++P +W++LVQVK Y+ +A+ A+ ++ EA +SA K +++ T+ ++ LP +E L K + EAL L EE +L M + L++ L+ L H + Q ++ N+HE +LL P++Q + SL +Q+ +D F++LGPI IF+++ R+V + R + GFGF+V+G P+ + NVE NS AE G+K GDF++++ D D++WSS + +V+
Sbjct: 32 TCRGKLQNKRSKLNQEINKELRLRAGAENLFKATTNRKLRETVALELSFVNSNLQLLKEQLAELNSSVELYQSDSMDSVMPMIPLGLKETKEIDFMDPFKDFILEHYSEDAFQYEDPITDFMDTRQAMRTPLRDNAGIALLFRYYNQLYFVERRFFPPDRSLGIYFEWFDSLTGVPSCQRTVAFEKACVLFNIGAIYTQIGTKQDRCTAKGLDSAVDSFLRAAGTFKYIHENFTNAPSMDLGPEMLEMLVQLMLAQAREC-LLEKLELQSREDRSVDI-SFDLAQEAAQLSQCYANVHQLITHETVR--DYVPYSWVSLVQVKREYFNGMAHYHAASGILH----------EAASQMSAATKDILRFLHVESTSTQLNIRLPKDDVERRLLGKAHLREALVLHEECQRLQRMCRELKSKLALTCVLRIAHSEAL-QSYTANEHEDDFRELLDPPQIQPSTK---FQLSLTAPDFAQHRVNDLFRALGPIAIFSAKRHWTAPRLVQLHRGRNSDGFGFSVRGDAPVIIANVESNSLAEFGGVKEGDFIVNILDKDVKWSSHDEVVKC 579
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Match: A0A151X327 (Rhophilin-2 OS=Trachymyrmex zeteki OX=64791 GN=ALC60_06461 PE=4 SV=1) HSP 1 Score: 344.739 bits (883), Expect = 7.052e-105 Identity = 199/577 (34.49%), Postives = 328/577 (56.85%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG---LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLA----NRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRD-QKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCS-LIKLTVTT 1869
T R KL R K+N++INK+LR+++GA NL + T ++++K + +E+ F SNL+L KE+L N +++ YQ++ + +PMIP+ +K T DIDF++ F++ + HY ED + Y EAI + R+A + P R + GI + YYN + IE+RFF PDRS GI F W D TGVP QRT FEK+ I+FN GALY+QLA+ + T GL+++ + FL + F +++ NF N PS+D+ P+ML+ML LM QA EC F +D S L+L E+ +++++ +V+ ++ E ++ +++P+ WI+L+ VK ++ ALA+K +A +R I F + + E I+ + T+ +P E L K + EAL L +ES +L M + L+ L+ L ++ ++ + + + +LL P++ + S+ Q+ D FKSLGP+ IF+++ R+V + R GFGF+V+G P+ V V+ NS A+ G+K GDF++ + D D++W+S E +V++ +C I L + T
Sbjct: 31 TCRGKLQNKRSKLNQEINKELRLRAGAENLFKATTNRKLKETVALELSFVNSNLQLLKEQLAELNSSVELYQNVDSTEPVMPMIPLGLKETKDIDFRDPFKDFILEHYSEDGENYEEAIADLMETRQATRTPTRDSAGIALLLRYYNQLYFIERRFFPPDRSLGIYFEWFDSLTGVPSCQRTVAFEKASILFNAGALYTQLAAKQDRLTARGLDQAVDAFLRAAGTFRYIHENFTNAPSMDLGPDMLEMLVQLMLAQARECLF--EKLELQSKDSRSIDVCLDLAQEAAQVAVIYNDVHGLISREPVR--DYVPETWISLILVKREHHLALAHKHIAVGLLDRPIAEFRVETKLTLEHIQKSDGK-------TQLDATIPRDDNERKLLGKAHLREALVLHDESQRLQRMCRELKGKQALAKVLKKAQEATLESYNRFGNEDDFRELLDPPDIIASTK---FQLSITHPDFGQHGVDDLFKSLGPVAIFSAKRHWTAPRLVQLQRGPDGEGFGFSVRGDAPVIVAAVDHNSLADVGGMKEGDFIVGIGDKDVKWASHEQVVRMIKQCGDFINLKLVT 593
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Match: A0A026X5U6 (Rhophilin-2 OS=Ooceraea biroi OX=2015173 GN=X777_16433 PE=4 SV=1) HSP 1 Score: 344.739 bits (883), Expect = 3.075e-104 Identity = 196/580 (33.79%), Postives = 324/580 (55.86%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG---LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIK-------PTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRD-QKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCS-LIKLTVTT 1869
T R KL R K+N++INK+LR+++GA NL + T ++++K + +E+ F SNL+L KE+L N +++ YQ++ +PMIP+ +K T DIDF++ F++ + HY ED + Y EAI + R+A + P R + GI + YYN + IE+RFF PDRS GI F W D TGVP QRT FEK+ I+FN GALY+QLA+ + T GL+++ + FL + F +++ NF N PS+D+ P+ML+ML LM QA EC F D + L+L E+ ++ ++ +V+ ++ E ++ +++P+ WI+L+ VK ++ ALA+K +A + I D E++ ++ T+ +P E L K + EAL L +ES +L M + L+ L+ L H++ +D + + + +LL P++ + S+ Q+ D F+SLGP+ IF+++ R+V + R GFGF+V+G P+ + V+ NS A+ G+K GDF++ + D D++W+S E +V++ +C I L + T
Sbjct: 80 TCRGKLQNKRSKLNQEINKELRLRAGAENLFKATTNRKLKETVALELSFVNSNLQLLKEQLAELNSSVELYQNVDGDEPVMPMIPLGLKETKDIDFRDPFKDFILEHYSEDGENYEEAIADLMETRQATRTPTRDSAGIALLLRYYNQLYFIERRFFPPDRSLGIYFEWFDSLTGVPSCQRTVAFEKASILFNAGALYTQLAAKQDRMTARGLDQAVDAFLRAAGTFRYIHENFTNAPSMDLGPDMLEMLVQLMLAQARECLF--EKLELQSRDGRNIDVCLDLAQEAAQVATIYNDVHGLISREPVR--DYVPETWISLILVKREHHLALAHKHIAVGLL----------DRPITDFRVEIRLTLEHIQKSDGKTQLDATVPRDDSERKLLGKAHLREALVLHDESQRLQRMCRDLKGKQALARVLKKAHEATLDSYNRFGSEDDFRELLDPPDIIASTK---FQLSITHPDFGQHGVDDLFRSLGPVAIFSAKRHWTAPRLVQLQRGPDGEGFGFSVRGDAPVIIAAVDHNSLADVGGMKEGDFIVGIGDKDVKWASHEQVVRMIKQCGDFINLKLVT 642
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Match: rhpn1 (rhophilin Rho GTPase binding protein 1 [Source:NCBI gene;Acc:103039738]) HSP 1 Score: 286.96 bits (733), Expect = 1.968e-86 Identity = 176/575 (30.61%), Postives = 313/575 (54.43%), Query Frame = 1
Query: 169 TQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ--DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYL--FMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMK-IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTIT 1875
TQRSKL + R K+N++IN++LR+++GA NL T ++++K +++E+ F SNL+L KEELE N +++ YQ K +PMIP+ +K T +ID ++ + HYGED Y+ ++ R+A++ P R++ G+ + YYN + +++RFF P R+ G+ F W D TGVP QR FEK ++FN+GALY+Q+ + ++T G++ + + F + F +L NF + PS+DM L ML LM Q EC + D SNL+A + ES +S ++ V ++++ LL+ +++P +W+++VQVK+ +++ALA+ A + K + A++ L +L P L P +L L K + +A+ EE+++L + K LR ++ L L+ H +++ +++ + + ++ PE+Q + T S +D F LGP+ +F +R + +G R + ++R + G G T++G P+ V V A ++GL GD++++++ D RW+ +V + CS + + IT
Sbjct: 33 TQRSKLQQRRAKLNQQINRELRLRTGAENLYRATTNQKVKETVSLELSFVNSNLQLLKEELEELNSSMEVYQTESEKVNVPMIPLGLKETKEIDMTIPLQDFISEHYGEDASLYMSEVKEFMDLRQAMRTPSRNDAGLELLMEYYNQLYFLDQRFFAPHRTLGVHFHWYDSLTGVPSCQRALAFEKGSVLFNIGALYTQIGARQDRSTLPGIQNAIDAFQRAAGAFLYLQENFSHAPSLDMSSPALSMLVRLMVAQVQECICERVTLTMEENDLMSNLQAAQ---ESARVSDVYSLVLQAMSVPLLK--DYVPFSWLSVVQVKTQHFRALAHYYTAAALCDCSDMIDKVNDCGSAVKAL--KLVHTRPPDTLCLQEPEDRLR---LGKGHLRKAIIRHEEALRLHGVCKMLRKMDILQEVLSYAHTRSLEKYSDIDQEDDFCEIAEAPEIQSHTYQ---KPDIKTPDFSSVRVTDIFHRLGPLSLFCARNRWVG--RRLCLVRGEA-GLGLTLRGDSPVLVAGVLPEGCAAEAGLHEGDYIVAVNGSDCRWAEHAEVVHVLKGCSERGVELDVIT 591
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Match: rhpn2 (rhophilin Rho GTPase binding protein 2 [Source:NCBI gene;Acc:103031065]) HSP 1 Score: 285.034 bits (728), Expect = 1.603e-85 Identity = 171/560 (30.54%), Postives = 308/560 (55.00%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTG--LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESY-DLLSCPEL--QVEARTGV-INQSLFTQIISQNPESDPFKSLGPIEIFNSRMK-IGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL R +N++I K +RM++GA NL++ T + +++ + +E+ + S+L+L E+LE N +++ YQ+++ +P+IP+ +K T D+DF F++ + HY ED Y + I+ + RKA + P R++ GI Y+ ++ +E RFF P+R GI F+W D FTGVP Q+ EK+ I+FN+ ALY+Q+ + + + T +GLEES F S +HL F + PS DM P ML ML +M QA EC F L + + FS L++ E+ + ++E V+ S+ ++ +++P W + QVK+++Y++LA+ ++ + L S D + QE A+ L + P H K E + K + A+ EE++++ + + LR L+ L++ L HK + + +K + + D + P++ + E + + + S+ ++ D F LGP+ +F+++ + P + + + D+ L GFT+KG P+++ +++ +A GLK GD+V+++ D D +W
Sbjct: 27 NPLAQTGRSKLQNQRASLNQQIIKQMRMRAGAENLLKATSNNKVRDMVMLELSYVNSDLQLLMEQLEGLNSSVEVYQNVQGTAIIPLIPLGLKETKDVDFSVPFKDFILEHYSEDGANYQDEIDDLMDLRKACRTPSRNDAGIELLANYFTQLSLLESRFFSPNRQMGIFFTWYDSFTGVPVCQQNMSLEKASILFNMAALYTQIGTRSDRQTSSGLEESITAFQRSAGVLSHLKETFTHTPSYDMSPAMLSMLVKMMFAQAQECLFEKLALPGIRNEFFS---LLKMAQEAAMVGEMYEQVHQSMIQTPIK--DNVPFFWSIMAQVKTHHYRSLAHYFVSTALLDHQLNPSDDEDKQEKALSQLYDAMPDGRSPLDVLRH----KDERRRIGKAHLQRAVVGQEEALRIQGLCRDLRKLSVLNDILQASHKRSLAKFEQKDKEDEFTDYMEAPDIISKTEQKAEMEVPASIKVKV------KDLFHRLGPLSVFSAKQRWTAPRTVRLKVEDRDL--GFTLKGDAPVQIQSLDPLCHAAADGLKEGDYVVAVGDADSKW 569
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Match: ptpn23a (protein tyrosine phosphatase non-receptor type 23 [Source:NCBI gene;Acc:103026294]) HSP 1 Score: 108.227 bits (269), Expect = 1.242e-23 Identity = 81/309 (26.21%), Postives = 145/309 (46.93%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQ----EAIEDLSAELKQLIKPTKYHLHLPSSKLEAL 1308
+PMI + +K + +F + + + +YGEDPD Y E ++ + R++ R EG Y+ +++++ R P + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F++L +F + SVDM ++L + NLM QA EC L + N ++ + S + ++ +L N + L I + W LVQ+K Y+ A+A +L M K Q E + L + L +L + K P S EAL
Sbjct: 7 MPMIWLDLKEAGEFEFGAAVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGPGQEAAVPISWTEIFSGKTVTHEDISYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFSYLRDHFSHSYSVDMSHQILNLNINLMLGQAQEC--------LLEKSMLDNRKSFLVARISAQVVDYYKEACRALENSDTASMLGKIQKDWKKLVQMKIYYFAAIA---------HLHMGKQAEEQQKYGERLAYLQSSLDKLNEAIKLAKGQPDSVQEAL 298
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Match: ptpn23a (protein tyrosine phosphatase non-receptor type 23 [Source:NCBI gene;Acc:103026294]) HSP 1 Score: 99.7525 bits (247), Expect = 4.644e-21 Identity = 90/353 (25.50%), Postives = 161/353 (45.61%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQ----EAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLI---------------NEALPLIE--ESIKLAAMNKYL 1389
+PMI + +K + +F + + + +YGEDPD Y E ++ + R++ R EG Y+ +++++ R P + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F++L +F + SVDM ++L + NLM QA EC + N ++ + S + ++ +L N + L I + W LVQ+K Y+ A+A +L M K Q E + L + L +L + K P S EAL + +I +EA+P +E S+K A + K L
Sbjct: 7 MPMIWLDLKEAGEFEFGAAVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGPGQEAAVPISWTEIFSGKTVTHEDISYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFSYLRDHFSHSYSVDMSHQILNLNINLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENSDTASMLGKIQKDWKKLVQMKIYYFAAIA---------HLHMGKQAEEQQKYGERLAYLQSSLDKLNEAIKLAKGQPDSVQEALRFTMDVIGGKFNSAKKDNDFIYHEAVPSLETLPSVKGAPLVKAL 342
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Match: ptpn23a (protein tyrosine phosphatase non-receptor type 23 [Source:NCBI gene;Acc:103026294]) HSP 1 Score: 96.6709 bits (239), Expect = 4.685e-20 Identity = 66/255 (25.88%), Postives = 126/255 (49.41%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAY 1158
+PMI + +K + +F + + + +YGEDPD Y E ++ + R++ R EG Y+ +++++ R P + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F++L +F + SVDM ++L + NLM QA EC + N ++ + S + ++ +L N + L I + W LVQ+K Y+ A+A+
Sbjct: 7 MPMIWLDLKEAGEFEFGAAVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGPGQEAAVPISWTEIFSGKTVTHEDISYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFSYLRDHFSHSYSVDMSHQILNLNINLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENSDTASMLGKIQKDWKKLVQMKIYYFAAIAH 253
BLAST of Rhophilin-2-like Protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004835.1 (pep scaffold:Pmarinus_7.0:GL480606:4394:25584:1 gene:ENSPMAG00000004381.1 transcript:ENSPMAT00000004835.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 236.498 bits (602), Expect = 7.282e-72 Identity = 122/338 (36.09%), Postives = 202/338 (59.76%), Query Frame = 1
Query: 166 QTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRAL-ELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLA 1170
QTQRSKL R K+N++INK++R+++GA NL+ T + ++K + +E+ F SNL+L KEEL N +++ YQ+ G+ P+IP+ +K T ++DF F+ +E HYGE +KY E I+ + R+A++ PRR+ G+ + YYN + +E RF P R +G+ F+W D TG+P QRT FE+ ++FN+GALY+Q+ + +T GL + + F + FN+L NF + P++DM P L ML LM Q EC F L L D + AL + E+ +S ++ + +++ + +++P +W +V+VKS ++ AL++ +A
Sbjct: 7 QTQRSKLQTRRAKLNQQINKEMRLRAGAENLLRATNNNKVKETVALELSFVNSNLQLLKEELAELNSSMEIYQNDSEGISVPLIPLGLKETKEVDFLTPFKAFIEEHYGECGEKYEEEIKDLLELRQAMRTPRRNEVGVELLMEYYNQLYFVENRFCPPHRHSGVFFTWYDSLTGMPACQRTLAFERGSVLFNVGALYTQIGARQDRTAHDGLHSAIDAFQKAAGAFNYLKENFTHAPTLDMSPASLTMLVRLMAAQVQECVFERFLLQGLHND----VPALFNIAQEATRVSDVYNVTHQTMDQTAIT--DYVPVSWRTMVRVKSLHFLALSHHYVA 338
BLAST of Rhophilin-2-like Protein vs. Ensembl Sea Lamprey
Match: ptpn23b (protein tyrosine phosphatase, non-receptor type 23, b [Source:ZFIN;Acc:ZDB-GENE-060503-179]) HSP 1 Score: 98.2117 bits (243), Expect = 3.630e-21 Identity = 69/275 (25.09%), Postives = 124/275 (45.09%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPD-RSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQE 1218
+PMI + +K D F ++ + + HYGE+PDKY E + R + R EG Y+ +++++ R + + + W D+FTG + FE++ I++NLGAL+S L S+ ++ G++ S +F + F +L +F + S DM +L + LM QA EC + N ++ + S ++ ++ L N E+ L + W +QVK +Y+ +A L+M K + Q+
Sbjct: 23 MPMISLELKIADDFPFVDAVKQYIFGHYGEEPDKYNEELRKFEQLRSSAVAVTRDFEGCSTLRKYFGQLHYLQSRVPMGEGQDAAVTVIWKDIFTGKAVKYDDIHFEQAAILYNLGALHSLLGVMDSRQSEEGMKVSCTHFQCAAGAFTYLRDHFSHSYSADMSLGILNLYITLMLGQAQECLL--------EKSMLDNRKSFLIARISAQVAEYYKEACHFLENHEVSSLLGREQKEWKKQIQVKISYFSCIA---------NLYMGKQADEQQ 280
BLAST of Rhophilin-2-like Protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001449.1 (pep scaffold:Pmarinus_7.0:GL478971:7755:10135:1 gene:ENSPMAG00000001310.1 transcript:ENSPMAT00000001449.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 46.9802 bits (110), Expect = 1.094e-6 Identity = 23/96 (23.96%), Postives = 50/96 (52.08%), Query Frame = 1
Query: 1594 GPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEM 1881
GP+ +F+++ R V ++ G+G ++G P++V VE S AE +G+K GD ++++ D +W+ +V+ +T+ ++ +
Sbjct: 1 GPLSVFSAKHSWTSPRSVKLVPCAD-GYGLVLRGDSPVRVATVETGSVAELAGVKNGDCIVALGGEDCKWAKHVDVVEAMRSADAAGVTLLIVSPL 95
BLAST of Rhophilin-2-like Protein vs. Ensembl Yeast
Match: RIM20 (Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation [Source:SGD;Acc:S000005801]) HSP 1 Score: 68.5514 bits (166), Expect = 1.886e-12 Identity = 68/266 (25.56%), Postives = 120/266 (45.11%), Query Frame = 1
Query: 406 MIPIAMKNTVDIDFKNSFRNILENHYGEDPDKY-IEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFT--GVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHL---NTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENV--YSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRF 1179
++ I +K T+++DF +++ + + + +++V++R AI P S +G+ YY ++ +EK+F P+ N I F+W + Q + +EK II+N+G +YS LA ++ L+ S YF N+ CF H+ N P VD L L +LM QA EC + +A++ + I+ L + + + I Q + I WIN ++ K Y+ A+ Y +A F
Sbjct: 4 LLAIPLKRTLEVDFATELSKLIDTTSFQTASFFQSDILKVVDARNNAIA-PDISIDGLSALKEYYVILLQLEKKF--PN--NQIEFTWFQTLSQKSRGTSQYSLQWEKLTIIYNIGCMYSLLALNSNNDAAESLKTSCLYFQNAAGCFKHVLDHQKNLETIPVVD--DATLNALTSLMLAQAQECFW---------------FKAVQDKHKDSLIAKLSQQIVDFYCEAINDAQRGKLIRSDWINHLKAKKAYFSAVTYYRIALSF 247
BLAST of Rhophilin-2-like Protein vs. Ensembl Yeast
Match: BRO1 (Cytoplasmic class E vacuolar protein sorting (VPS) factor; coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes [Source:SGD;Acc:S000006005]) HSP 1 Score: 62.003 bits (149), Expect = 2.443e-10 Identity = 45/189 (23.81%), Postives = 86/189 (45.50%), Query Frame = 1
Query: 406 MIPIAMKNTVDIDFKNSFRNILENHYGED------PDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDV-----FTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAME 939
+ + +K+T +D+K + L+ YG +K ++ + + P +E ++ YY+ + H+ R + F+W D G+ + Q T FEKS +FN+ +++Q+A + + S + +CF +L+ NF+N PSVD++ E + LAN+ +A E
Sbjct: 5 LFDLKLKDTEKLDWKKGLSSYLKKSYGSSQWRTFYDEKATSELDHLRNNANGELAPSSLSE---QNLKYYSFLEHLYFRLGSKGSRLKMDFTWYDAEYSSAQKGLKYTQHTLAFEKSCTLFNIAVIFTQIAR---ENINEDYKNSIANLTKAFSCFEYLSENFLNSPSVDLQSENTRFLANICHAEAQE 187
BLAST of Rhophilin-2-like Protein vs. Ensembl Nematostella
Match: EDO34525 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP33]) HSP 1 Score: 261.922 bits (668), Expect = 4.602e-77 Identity = 179/632 (28.32%), Postives = 297/632 (46.99%), Query Frame = 1
Query: 82 SMNSSSKMSEKFETLAIENRDRKNNRIF-QTQRSKLHENREKINEKINKDLRMKSGARNLIEL---TKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQ---DLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEA-----IEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLF--TQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVN------------------------------------VEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQ 1827
+ N +K T+A R+ +N ++ ++ R +L R+ +N KI+K +++ GA NLI+ T D+++K +E+ F L +EELE NC+LD YQ ++ +PMIP+ ++ T D+DF + F+ L++HY EDP+KY E RK + P R +GI+ YYN + +E++FF S + F W D TG+P QR++ FEK+ ++FN+GAL+SQ+ + + T G+EE+ F + F + NF+N PSVDM + L+ L LM VQA C + L D F ++ E IS ++ V +N + ++ IP AW NLV++ S +YKAL++ A + + E I D+ + K+ K K HLH AL EE+++ + ++ R + L L ++L + + + +D P V+A + Q F + P D F LGP+ IFN+ +G +R V I R+ FGF+V G PM + + ++ A ++G++VGD V+ ++ D++W +V+
Sbjct: 20 TTNPVTKKRRSHGTVARVLRENENAAVYRESGRWQLQHKRQALNRKIHKQTKLRDGAENLIKALKSTNDRKLKHAARMELSFASFQLDQLQEELEGINCSLDVYQFDGTMEKQVPMIPLGLRETQDVDFCSQFKEFLQDHYDEDPEKYTEEFARYRKLRKTMCNPSRDKDGILSLYEYYNQMYFVERKFFPKRGSMAVYFHWYDAMTGLPKVQRSAAFEKASVMFNIGALWSQIGTKQDRGTAEGVEEACMAFQKAAGAFRFIRDNFMNSPSVDMTQDTLEALIPLMLVQAQACMWEKRRLLHDDVDGFQE--CIQAGQECAEISQGYKRVQLLMNSGIC--MDSIPTAWRNLVKIMSAHYKALSHYHTAAGLLQCPAGETSGLHEMLSSLYISDMDSGPKRK-KQAKAHLHA-----------------ALRHHEEAMRARQVCRFCRRVLSLHKVLTVARDMSTNKLVGMEEEDDFDAPLAP-TPVKA---YVRQKAFPISPEFHMAPVEDLFYKLGPVHIFNAENTLGASRTVTIHRENG-SFGFSVIGSAPMIIQSIDDQGAAWVSNDQEAAWVIDDQEAAWVIDDQRPFWVIDSQGAASEAGVQVGDIVIGVNGEDVKWGEHHDVVE 624
BLAST of Rhophilin-2-like Protein vs. Ensembl Nematostella
Match: EDO45795 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRP2]) HSP 1 Score: 75.485 bits (184), Expect = 4.799e-14 Identity = 64/262 (24.43%), Postives = 118/262 (45.04%), Query Frame = 1
Query: 409 IPIAMKNTVDIDFKNSFRNILENHYGEDPDKY-IEAIELVNSRRKA--IQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVF-TGVPFQQR-----TSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFV----NPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALA 1155
I I K + +DFK ++N + ED K +AI +N R + +Q P + + + YY+ + IE + + + F+W D F G F + TS +E+ ++FN+GAL SQ+AS + T GL+ + F ++ CFN L + P+ DM EML L ++M Q E + K+ + + + A +S + + ++ ++ + + + W ++ K Y+KA++
Sbjct: 5 IVIPCKRSEAVDFKKPLEKFIKNTFSEDVLKENSDAISDLNKLRNSAVMQTPDKHESALEPLLRYYDQLVAIEGKLPINESQIRVSFTWFDCFDKGSLFGYKKASLATSAYERLCLLFNIGALESQIASAQNLQTDDGLKLAAKMFQSASGCFNLLKDSVYAQLHQVPTPDMSVEMLNALGSIMLAQGQESIWFKTEHDKMKDGIIAKVAA--------QLSDFYNEANQACQVQTVK--QQLEKEWTAVLGAKQKYFKAIS 256
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Match: rhpn1 (rhophilin Rho GTPase binding protein 1 [Source:NCBI gene;Acc:101168940]) HSP 1 Score: 295.819 bits (756), Expect = 1.479e-89 Identity = 179/586 (30.55%), Postives = 310/586 (52.90%), Query Frame = 1
Query: 166 QTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGL--PMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLS-----------AELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYD-LLSCPELQVEA--RTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTIT 1875
QTQRSKL R +IN++INK++RM++GA NL T + ++K + +E+ F SNL+L KEELE N ++ YQ + PMIP+ +K T D+DF ++ + HYGED +Y + + R+A++ P R+ G+ + YYN + ++++RFF R+ G+ F W D TGVP QR FEK ++FN+GALY+Q+ + + A ++ + + F + FN+L NF N PS+DM L ML LM Q EC F + S LR L E+ +S ++ V ++ L++ +++P W ++VQVKS +++AL++ A +S + + + L+Q+++ + K LG + L AL EE+++L + K LR ++ L + L+ HK +D+ +L++ + +D PE+Q ++ + V + T + +D F+ LGP+ +F +R + GP R++ + R + G G T++G P+ V V AE++GL+ GD+++++D D +W+ +V + CS ++ +T
Sbjct: 44 QTQRSKLQHRRARINQQINKEMRMRAGAENLFRATTNNKVKETVALELSFVNSNLQLLKEELEELNSNMEVYQTDSEAVKVPMIPLGLKETKDVDFTIPIQDFICEHYGEDSSQYDREVRELMELRQAMRTPSRNQAGLELLMEYYNQLYYVDQRFFSAHRNLGVHFHWYDSLTGVPSSQRALAFEKGSVLFNIGALYTQIGARQDRCATADIDAAIDAFQRAAGAFNYLKENFSNAPSLDMSAPSLSMLVRLMLAQVQECVFERIALASRSAHFSSQLR---LSQEAARVSDVYLLVQQTMTQPLMK--DYVPFPWASMVQVKSEHFRALSHYYAAAALCEHTLSAKEEEGDQEAEEAFLGFYANVPAGQSLRQVLQDAE--------KRRKLGKAHLRC--ALIRHEEAMRLHGLCKILRKMDILQDVLSLAHKRSLDKYSALDREDDFDETAEAPEIQAQSQQKPDVTPPNFSTVQV-----TDIFQRLGPLSVFCARARWGPVRVICLQRREG-GLGLTLRGDSPVLVAGVVPGGCAEEAGLREGDYIVAVDGLDCKWAKHAEVVHLLKSCSDSGTDISVVT 608
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Match: rhpn2 (rhophilin Rho GTPase binding protein 2 [Source:NCBI gene;Acc:101173292]) HSP 1 Score: 262.692 bits (670), Expect = 3.122e-77 Identity = 175/569 (30.76%), Postives = 300/569 (52.72%), Query Frame = 1
Query: 154 NRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLK--TGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFI--YLFMSKDVNSQE-AIEDLSAELKQLIKPTKYHLHLPSSKL-EALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKH-------------ESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRW 1803
N + QT RSKL + R +N++I K +R+++GA NL++ T + ++K + +E+ F S+L+L +L+ N ++D YQ+ + +P+I + +K T ++DF F++ + HY ED K+ + I + R+A + P RS G+ YYN + IE RFF P GI F+W D FTGVP Q+ EK+ I+FN+ AL+SQ+ + +++ T AGLEE+ + F + N+L F + PS DM P ML ML LM QA EC F L +KF+ + +++ E+ ++ +++ V+ + I+ Q +++P W + QVK+N+Y ++A+ +A + L D + QE + + + P L ++L E LG K I ++ EE++++ M L N + L + L H HSL+K+ E+ ++LS E + E T S+ D F LGP+ +F+++ P R V + + + GFT+KG P++VV+++ A K GLK GD+++++ D + +W
Sbjct: 25 NPLAQTGRSKLQKERAVLNQQIIKQMRIRAGAENLLKATSNNKVKEMVLLELSFVNSDLQLLMGQLDALNSSVDVYQNKQETVNIPLIALGLKETKEVDFSAPFKDFIMEHYNEDSRKFEDEIADLMDLREACRTPSRSEAGVELLEKYYNHLPMIESRFFAPTNQTGIFFTWYDSFTGVPVCQQNLSLEKASILFNMAALFSQIGTRSNRQTTAGLEEAISSFQKASGILNYLKETFTHTPSFDMGPAMLSMLIRLMLAQAQECLF-EKSVLPGTRNKFNAM--IKVAQEAAKVAEVYDQVHQCM-IQ-TQLKDNVPLFWSTMTQVKTNHYSSMAHYFVAVALLDHQLGPKDDEDHQEKTFSQVYDQFPEGWTPLDV---LKQTELRERLG--KAHIRKSTSGHEEALRIFDMCPNLNNHDVLRDILKTSH------YHSLDKYTEFENEEEFTDYMEAPNILSKTERKAEMETPS---------TSKVKVKDFFHRLGPLTVFSAKQHWTPPRTVRLCPEGR-DLGFTLKGGSPVQVVSLDPLCVAAKDGLKEGDYIVAVGDTECKW 567
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Match: ptpn23a (protein tyrosine phosphatase non-receptor type 23 [Source:NCBI gene;Acc:101156355]) HSP 1 Score: 100.523 bits (249), Expect = 2.829e-21 Identity = 67/255 (26.27%), Postives = 124/255 (48.63%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAY 1158
+PMI + +K + F S R + +YGE+PD Y E ++ + + R++ R EG Y+ +++++ R + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F +L +F + SVDM ++L + NLM QA EC + N ++ + S + ++ +L N E L I + W LVQ+K Y+ A+A+
Sbjct: 7 MPMIWLDLKEAGEFQFSPSVRQFILKNYGENPDNYNEQMKKLETLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPMGAGQEAAVPISWTEIFSGKNVTHDDISYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFTYLRDHFSHNFSVDMSHQILNLNINLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENSETASMLGKIQKDWKKLVQMKIYYFAAIAH 253
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Match: ptpn23a (protein tyrosine phosphatase non-receptor type 23 [Source:NCBI gene;Acc:101156355]) HSP 1 Score: 92.4337 bits (228), Expect = 1.032e-18 Identity = 71/275 (25.82%), Postives = 129/275 (46.91%), Query Frame = 1
Query: 400 LPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRF-FFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSL-NIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQE 1218
+PMI + +K + F S R + +YGE+PD Y E ++ + + R++ R EG Y+ +++++ R + + SW ++F+G +E++ I++NLGAL+S L + ++ ++ G++ S +F S F +L +F + SVDM ++L + NLM QA EC + N ++ + S + ++ +L N E L I + W LVQ+K Y+ A+A +L M K Q+
Sbjct: 7 MPMIWLDLKEAGEFQFSPSVRQFILKNYGENPDNYNEQMKKLETLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPMGAGQEAAVPISWTEIFSGKNVTHDDISYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFTYLRDHFSHNFSVDMSHQILNLNINLMLGQAQECLL--------EKSMLDNRKSFLVARISAQVVDYYKEACRALENSETASMLGKIQKDWKKLVQMKIYYFAAIA---------HLHMGKQAEEQQ 264
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:NCBI gene;Acc:101156751]) HSP 1 Score: 72.4034 bits (176), Expect = 1.208e-12 Identity = 56/223 (25.11%), Postives = 107/223 (47.98%), Query Frame = 1
Query: 409 IPIAMKNTVDIDFKNSFRNILENHY--GEDPDKYIEAIELVNSRRK-AIQYPRRSNEGIIDHIL-YYNLINHIEKRFFFPDRSNGIIFSWNDVF-------TGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNP----PSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNL--RALELVGESF 1026
I + +K + ++D + Y GED +YI A+E +N RK A+ P ++ ++ +L YY+ + +E +F F + + F+W D F V + +EK+ ++FN AL SQ+A+ + L+ + Y+ + F+H+ ++ P++D+ PE + L+ +M QA E FL K+ + + L +A + G++F
Sbjct: 5 ISVPLKKSSEVDLVKPLSKYITVTYPAGEDQTEYIRAVEELNKLRKNALGRPLDKHDSSLEILLRYYDQLCALEPKFPFSENQICLSFTWKDAFDKGSLFGGSVKLSLASLGYEKTCVLFNCAALASQIAAEQNMDNDECLKTAAKYYQLASGAFSHIKDTVLSALSREPTMDICPETVGTLSLIMLAQAQEVFFLKATSDKMKDAVIAKLANQAADFYGDAF 227
BLAST of Rhophilin-2-like Protein vs. Planmine SMEST
Match: SMESG000022872.1 (SMESG000022872.1) HSP 1 Score: 1306.2 bits (3379), Expect = 0.000e+0 Identity = 660/663 (99.55%), Postives = 661/663 (99.70%), Query Frame = 1
Query: 85 MNSSSKMSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKSSQPDXXXXXXPNRKTGKLSWKQRLSGTLXXXXXXXXQPQTVSTLF 2073
MNSSSKMSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGI DHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFLLLLKLKLLEDKFSNLRALELVGESFA+SILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKS QPDSLSLSLPNRKTGKLSWKQRLSGTLKKKSSKSSQPQTVSTLF
Sbjct: 1 MNSSSKMSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGISDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFLLLLKLKLLEDKFSNLRALELVGESFAVSILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKSLQPDSLSLSLPNRKTGKLSWKQRLSGTLKKKSSKSSQPQTVSTLF 663
BLAST of Rhophilin-2-like Protein vs. Planmine SMEST
Match: SMESG000022872.1 (SMESG000022872.1) HSP 1 Score: 1292.72 bits (3344), Expect = 0.000e+0 Identity = 654/657 (99.54%), Postives = 655/657 (99.70%), Query Frame = 1
Query: 103 MSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGIIDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKSSQPDXXXXXXPNRKTGKLSWKQRLSGTLXXXXXXXXQPQTVSTLF 2073
MSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGI DHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFLLLLKLKLLEDKFSNLRALELVGESFA+SILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKS QPDSLSLSLPNRKTGKLSWKQRLSGTLKKKSSKSSQPQTVSTLF
Sbjct: 1 MSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRMKSGARNLIELTKDKRIKSKINIEIDFFESNLKLWKEELERANCALDTYQDLKTGLPMIPIAMKNTVDIDFKNSFRNILENHYGEDPDKYIEAIELVNSRRKAIQYPRRSNEGISDHILYYNLINHIEKRFFFPDRSNGIIFSWNDVFTGVPFQQRTSVFEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVNPPSVDMKPEMLQMLANLMRVQAMECKFLLLLKLKLLEDKFSNLRALELVGESFAVSILFENVYSSLNIELLQFLEHIPQAWINLVQVKSNYYKALAYKMLANRFIYLFMSKDVNSQEAIEDLSAELKQLIKPTKYHLHLPSSKLEALGLSKLLINEALPLIEESIKLAAMNKYLRNLNDLSNFLNNEHKSWIDQLHSLNKHESYDLLSCPELQVEARTGVINQSLFTQIISQNPESDPFKSLGPIEIFNSRMKIGPARIVVIIRDQKLGFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKCSLIKLTVTTITEMGLTRNHTFSTSAPFDLNKSLQPDSLSLSLPNRKTGKLSWKQRLSGTLKKKSSKSSQPQTVSTLF 657
BLAST of Rhophilin-2-like Protein vs. Planmine SMEST
Match: SMESG000019014.1 (SMESG000019014.1) HSP 1 Score: 53.9138 bits (128), Expect = 4.106e-7 Identity = 46/189 (24.34%), Postives = 87/189 (46.03%), Query Frame = 1
Query: 631 FPDRSNG--IIFSWNDVFTGVP-FQQRTSV------FEKSGIIFNLGALYSQLASGTSKTTQAGLEESQNYFLNSEACFNHLNTNFVN----PPSVDMKPEMLQMLANLMRVQAMECKFXXXXXXXXXEDKFSNLRALELVGESFAISILFENVYSSLNIELLQFLEHI-PQAWINLVQVKSNYYKALA 1155
P NG I F W+D F F ++ S+ +E+ ++FN+ A+YSQ+A + + +GL+ + YF + F++L ++ N P+ D+ + L L +M QA E + ++ + + + ++ V + +A L + L ++ I P+ WI +V K Y A+A
Sbjct: 80 IPIAENGVRIDFKWDDAFAKDSLFGKKGSLKIASGGYERICVLFNIAAMYSQVAETANLSDDSGLKTAAKYFQQAAGIFSYLRSSVPNIIQREPTYDLNGDTLSALNVIMLAQAQELIYTKAVRDSHKDGNIAKI--VQQVADLYA---------DGLKLMQLNSVKAIWPKDWIPIVAGKQAGYHAMA 257
BLAST of Rhophilin-2-like Protein vs. Planmine SMEST
Match: SMESG000022937.1 (SMESG000022937.1) HSP 1 Score: 51.2174 bits (121), Expect = 2.662e-6 Identity = 21/57 (36.84%), Postives = 39/57 (68.42%), Query Frame = 1
Query: 1672 GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC 1842
GFGFT+ G P+ V +V+ +S+AE +G+ GD ++ +D++++ SS E +V++ C
Sbjct: 422 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 478 The following BLAST results are available for this feature:
BLAST of Rhophilin-2-like Protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Rhophilin-2-like Protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Rhophilin-2-like Protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Rhophilin-2-like Protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Rhophilin-2-like Protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Rhophilin-2-like Protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033108 ID=SMED30033108|Name=Rhophilin-2-like Protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2194bpback to top protein sequence of SMED30033108-orf-1 >SMED30033108-orf-1 ID=SMED30033108-orf-1|Name=SMED30033108-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=664bp MNSSSKMSEKFETLAIENRDRKNNRIFQTQRSKLHENREKINEKINKDLRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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