Dvl-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033103 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Dvl-2 vs. Ensembl Human
Match: DVL3 (dishevelled segment polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:3087]) HSP 1 Score: 210.69 bits (535), Expect = 1.717e-56 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+I+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 245 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTG 370 HSP 2 Score: 163.696 bits (413), Expect = 4.892e-41 Identity = 73/134 (54.48%), Postives = 105/134 (78.36%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ER ++ HL+ ++D+ I++ ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY ++EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ NM+ LSL + S G + LA LP P
Sbjct: 397 DTERL-DDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS--GASDQDTLAPLPHP 527 HSP 3 Score: 136.346 bits (342), Expect = 3.604e-32 Identity = 59/82 (71.95%), Postives = 70/82 (85.37%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+D +ETPYL+KL + ++VTL D K L RP YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+AEGS
Sbjct: 3 ETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGS 84
BLAST of Dvl-2 vs. Ensembl Human
Match: DVL1 (dishevelled segment polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:3084]) HSP 1 Score: 204.527 bits (519), Expect = 8.646e-55 Identity = 93/127 (73.23%), Postives = 107/127 (84.25%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNIVTV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V + GPI+L VAKCWDP P+ YFT+PR +PVRPIDP AW+ HT A+T
Sbjct: 247 LNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGA 373 HSP 2 Score: 156.377 bits (394), Expect = 8.029e-39 Identity = 72/132 (54.55%), Postives = 99/132 (75.00%), Query Frame = 2
Query: 1544 RYQ-EELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
RY+ EE LT +D+ ++RV+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY H+EGF +R+EARKYA++LLK G+++HTVNK+TFSEQCYYV G+ N++ L+L+ S G + LA LP P
Sbjct: 376 RYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSS----GTSDQDTLAPLPHP 503 HSP 3 Score: 135.191 bits (339), Expect = 6.595e-32 Identity = 62/85 (72.94%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+DEEETPYL+KL ++P++VTL D KN L NRP YK+FFKSMD DFGVVKEEI DD AKLPCF GRV+SWLV AEG+
Sbjct: 3 ETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGA 87
BLAST of Dvl-2 vs. Ensembl Human
Match: DVL2 (dishevelled segment polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:3086]) HSP 1 Score: 205.682 bits (522), Expect = 9.254e-55 Identity = 92/126 (73.02%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+ YFT+PR EP++PIDP AWV H+ A+T
Sbjct: 263 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTG 388 HSP 2 Score: 151.369 bits (381), Expect = 6.539e-37 Identity = 64/111 (57.66%), Postives = 90/111 (81.08%), Query Frame = 2
Query: 1505 SIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
S +T+ SSLP+ E L+ +TD+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF +R+EARKYA+ LLK G I+HTVNK+TFSEQCYYV G+
Sbjct: 400 STITSGSSLPDG---CEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGD 507 HSP 3 Score: 126.331 bits (316), Expect = 5.765e-29 Identity = 53/81 (65.43%), Postives = 69/81 (85.19%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET++IYH+DEEETPYL+K+ + +++TLGD K+ L RP KYFFKSMD DFGVVKEEI+DD A+LPCF GRV+SWLV+++
Sbjct: 13 ETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSD 93
BLAST of Dvl-2 vs. Ensembl Human
Match: DVL2 (dishevelled segment polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:3086]) HSP 1 Score: 205.682 bits (522), Expect = 9.299e-55 Identity = 92/126 (73.02%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+ YFT+PR EP++PIDP AWV H+ A+T
Sbjct: 257 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTG 382 HSP 2 Score: 150.984 bits (380), Expect = 7.126e-37 Identity = 64/111 (57.66%), Postives = 90/111 (81.08%), Query Frame = 2
Query: 1505 SIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
S +T+ SSLP+ E L+ +TD+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF +R+EARKYA+ LLK G I+HTVNK+TFSEQCYYV G+
Sbjct: 394 STITSGSSLPDG---CEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGD 501 HSP 3 Score: 125.946 bits (315), Expect = 6.371e-29 Identity = 53/81 (65.43%), Postives = 69/81 (85.19%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET++IYH+DEEETPYL+K+ + +++TLGD K+ L RP KYFFKSMD DFGVVKEEI+DD A+LPCF GRV+SWLV+++
Sbjct: 13 ETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSD 93
BLAST of Dvl-2 vs. Ensembl Human
Match: DVL1 (dishevelled segment polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:3084]) HSP 1 Score: 204.527 bits (519), Expect = 1.484e-54 Identity = 93/127 (73.23%), Postives = 107/127 (84.25%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNIVTV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V + GPI+L VAKCWDP P+ YFT+PR +PVRPIDP AW+ HT A+T
Sbjct: 247 LNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGA 373 HSP 2 Score: 155.221 bits (391), Expect = 2.704e-38 Identity = 70/128 (54.69%), Postives = 96/128 (75.00%), Query Frame = 2
Query: 1553 EELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
EE LT +D+ ++RV+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY H+EGF +R+EARKYA++LLK G+++HTVNK+TFSEQCYYV G+ N++ L+L+ S G + LA LP P
Sbjct: 405 EEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSS----GTSDQDTLAPLPHP 528 HSP 3 Score: 135.191 bits (339), Expect = 7.319e-32 Identity = 62/85 (72.94%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+DEEETPYL+KL ++P++VTL D KN L NRP YK+FFKSMD DFGVVKEEI DD AKLPCF GRV+SWLV AEG+
Sbjct: 3 ETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGA 87
BLAST of Dvl-2 vs. Ensembl Celegans
Match: dsh-1 (DiSHevelled related [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU4]) HSP 1 Score: 163.696 bits (413), Expect = 4.585e-43 Identity = 82/127 (64.57%), Postives = 99/127 (77.95%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIP---RQEPVRPIDPRAWVLHTNAM 1222
L+++TV LNMDTV FLGISIVGQ++ GD GIYV +IMKGGAVA DGRIE GDMIL+VN+ SFE+ +ND AV LRE V + GPI L VAK ++ N + FTIP R+EPVRPID +AW+ HTNAM
Sbjct: 103 LDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFE-NGQSCFTIPRNSREEPVRPIDTQAWIQHTNAM 228 HSP 2 Score: 125.946 bits (315), Expect = 2.444e-30 Identity = 61/137 (44.53%), Postives = 90/137 (65.69%), Query Frame = 2
Query: 1466 PMGMPGQFSQG---AGSIVTTSSSLPESERYQEELH--LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRL 1861
P +PG++ G + S VT++ S ++ H L +TD ++ +++ P SGLDI++R WLKI +P +F+GS+LV+WL H+EG +RK AR +AA+LLK YI H VNKVTF+EQCYYVLG+ + +R
Sbjct: 240 PTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARF 376
BLAST of Dvl-2 vs. Ensembl Celegans
Match: dsh-1 (DiSHevelled related [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU4]) HSP 1 Score: 164.081 bits (414), Expect = 1.135e-42 Identity = 82/127 (64.57%), Postives = 99/127 (77.95%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIP---RQEPVRPIDPRAWVLHTNAM 1222
L+++TV LNMDTV FLGISIVGQ++ GD GIYV +IMKGGAVA DGRIE GDMIL+VN+ SFE+ +ND AV LRE V + GPI L VAK ++ N + FTIP R+EPVRPID +AW+ HTNAM
Sbjct: 103 LDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFE-NGQSCFTIPRNSREEPVRPIDTQAWIQHTNAM 228 HSP 2 Score: 125.946 bits (315), Expect = 5.400e-30 Identity = 61/137 (44.53%), Postives = 90/137 (65.69%), Query Frame = 2
Query: 1466 PMGMPGQFSQG---AGSIVTTSSSLPESERYQEELH--LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRL 1861
P +PG++ G + S VT++ S ++ H L +TD ++ +++ P SGLDI++R WLKI +P +F+GS+LV+WL H+EG +RK AR +AA+LLK YI H VNKVTF+EQCYYVLG+ + +R
Sbjct: 240 PTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARF 376
BLAST of Dvl-2 vs. Ensembl Celegans
Match: dsh-1 (DiSHevelled related [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU4]) HSP 1 Score: 164.081 bits (414), Expect = 6.731e-42 Identity = 82/127 (64.57%), Postives = 99/127 (77.95%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIP---RQEPVRPIDPRAWVLHTNAM 1222
L+++TV LNMDTV FLGISIVGQ++ GD GIYV +IMKGGAVA DGRIE GDMIL+VN+ SFE+ +ND AV LRE V + GPI L VAK ++ N + FTIP R+EPVRPID +AW+ HTNAM
Sbjct: 299 LDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFE-NGQSCFTIPRNSREEPVRPIDTQAWIQHTNAM 424 HSP 2 Score: 125.561 bits (314), Expect = 1.966e-29 Identity = 61/137 (44.53%), Postives = 90/137 (65.69%), Query Frame = 2
Query: 1466 PMGMPGQFSQG---AGSIVTTSSSLPESERYQEELH--LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRL 1861
P +PG++ G + S VT++ S ++ H L +TD ++ +++ P SGLDI++R WLKI +P +F+GS+LV+WL H+EG +RK AR +AA+LLK YI H VNKVTF+EQCYYVLG+ + +R
Sbjct: 436 PTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARF 572 HSP 3 Score: 73.559 bits (179), Expect = 5.153e-13 Identity = 39/87 (44.83%), Postives = 56/87 (64.37%), Query Frame = 2
Query: 107 TRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGV-VKEEITDDEAKL-PCFKGRVISWLVTAEGSTVSD 361
T++ HID+E PY++++ + PD +TLGDLK L R ++KY+ K++D D G VK EI DD +L P +L+T EGST SD
Sbjct: 72 TKVYCHIDDETDPYMLEVHVPPDLITLGDLKRVLMRTNFKYYRKALDPDSGYEVKAEIRDDSQRLTPSPNNLFELFLLTIEGSTHSD 158
BLAST of Dvl-2 vs. Ensembl Celegans
Match: dsh-1 (DiSHevelled related [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU4]) HSP 1 Score: 164.466 bits (415), Expect = 9.258e-42 Identity = 82/127 (64.57%), Postives = 99/127 (77.95%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIP---RQEPVRPIDPRAWVLHTNAM 1222
L+++TV LNMDTV FLGISIVGQ++ GD GIYV +IMKGGAVA DGRIE GDMIL+VN+ SFE+ +ND AV LRE V + GPI L VAK ++ N + FTIP R+EPVRPID +AW+ HTNAM
Sbjct: 299 LDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFE-NGQSCFTIPRNSREEPVRPIDTQAWIQHTNAM 424 HSP 2 Score: 125.946 bits (315), Expect = 2.559e-29 Identity = 61/137 (44.53%), Postives = 90/137 (65.69%), Query Frame = 2
Query: 1466 PMGMPGQFSQG---AGSIVTTSSSLPESERYQEELH--LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRL 1861
P +PG++ G + S VT++ S ++ H L +TD ++ +++ P SGLDI++R WLKI +P +F+GS+LV+WL H+EG +RK AR +AA+LLK YI H VNKVTF+EQCYYVLG+ + +R
Sbjct: 436 PTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARF 572 HSP 3 Score: 73.559 bits (179), Expect = 4.715e-13 Identity = 39/87 (44.83%), Postives = 56/87 (64.37%), Query Frame = 2
Query: 107 TRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGV-VKEEITDDEAKL-PCFKGRVISWLVTAEGSTVSD 361
T++ HID+E PY++++ + PD +TLGDLK L R ++KY+ K++D D G VK EI DD +L P +L+T EGST SD
Sbjct: 72 TKVYCHIDDETDPYMLEVHVPPDLITLGDLKRVLMRTNFKYYRKALDPDSGYEVKAEIRDDSQRLTPSPNNLFELFLLTIEGSTHSD 158
BLAST of Dvl-2 vs. Ensembl Celegans
Match: dsh-1 (DiSHevelled related [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU4]) HSP 1 Score: 166.007 bits (419), Expect = 1.092e-41 Identity = 82/127 (64.57%), Postives = 99/127 (77.95%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIP---RQEPVRPIDPRAWVLHTNAM 1222
L+++TV LNMDTV FLGISIVGQ++ GD GIYV +IMKGGAVA DGRIE GDMIL+VN+ SFE+ +ND AV LRE V + GPI L VAK ++ N + FTIP R+EPVRPID +AW+ HTNAM
Sbjct: 578 LDVITVNLNMDTVNFLGISIVGQTSNCGDNGIYVANIMKGGAVALDGRIEAGDMILQVNETSFENFTNDQAVDVLREAVSRRGPIKLTVAKSFE-NGQSCFTIPRNSREEPVRPIDTQAWIQHTNAM 703 HSP 2 Score: 126.331 bits (316), Expect = 3.260e-29 Identity = 61/137 (44.53%), Postives = 90/137 (65.69%), Query Frame = 2
Query: 1466 PMGMPGQFSQG---AGSIVTTSSSLPESERYQEELH--LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRL 1861
P +PG++ G + S VT++ S ++ H L +TD ++ +++ P SGLDI++R WLKI +P +F+GS+LV+WL H+EG +RK AR +AA+LLK YI H VNKVTF+EQCYYVLG+ + +R
Sbjct: 715 PTPIPGEWPHGRPPSSSTVTSNGSNGQNTVVGGGAHIILDIHTDKKKVVEIMAMPGSGLDIKNRTWLKIPIPMSFLGSDLVEWLLDHVEGLRERKTARNFAADLLKLKYIAHVVNKVTFTEQCYYVLGDECSDYARF 851
BLAST of Dvl-2 vs. Ensembl Fly
Match: dsh (gene:FBgn0000499 transcript:FBtr0073454) HSP 1 Score: 226.868 bits (577), Expect = 5.076e-63 Identity = 104/129 (80.62%), Postives = 116/129 (89.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGAS 1237
LNI+TV +NM+ V FLGISIVGQSN+GGDGGIYVGSIMKGGAVA DGRIEPGDMIL+VND++FE+M+ND+AVR LRE VQKPGPI LVVAKCWDPNPKGYFTIPR EPVRPIDP AWV HT A+T+ S
Sbjct: 248 LNIITVSINMEAVNFLGISIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPGPIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALTSHDS 376 HSP 2 Score: 122.479 bits (306), Expect = 2.685e-28 Identity = 57/89 (64.04%), Postives = 69/89 (77.53%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH--YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDN 364
ET++IYHID+E TPYL+K+ I +VTL D K LN+ + YKYFFKSMD DFGVVKEEI DD LPCF GRV+SWLV+A+G+ SDN
Sbjct: 10 ETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLNKQNNNYKYFFKSMDADFGVVKEEIADDSTILPCFNGRVVSWLVSADGTNQSDN 98 HSP 3 Score: 119.013 bits (297), Expect = 3.231e-27 Identity = 47/80 (58.75%), Postives = 68/80 (85.00%), Query Frame = 2
Query: 1592 ILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVL 1831
I++ +++PDSGL+IRDR+WLKIT+PNAFIG++ V+W+ ++E DR+EAR+ + +L+ YIKHTVNK+TFSEQCYYV+
Sbjct: 397 IVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYIKHTVNKLTFSEQCYYVV 476
BLAST of Dvl-2 vs. Ensembl Fly
Match: baz (gene:FBgn0000163 transcript:FBtr0111000) HSP 1 Score: 53.1434 bits (126), Expect = 1.514e-6 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 932 GDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQV-----QKPGPINLVVAK 1123
GD GI+V +++ GGA ++DGR+ D +L VN +S +N +A+ TLR + + PG I L+V +
Sbjct: 687 GDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGR 755
BLAST of Dvl-2 vs. Ensembl Fly
Match: baz (gene:FBgn0000163 transcript:FBtr0343763) HSP 1 Score: 53.1434 bits (126), Expect = 1.672e-6 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 932 GDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQV-----QKPGPINLVVAK 1123
GD GI+V +++ GGA ++DGR+ D +L VN +S +N +A+ TLR + + PG I L+V +
Sbjct: 666 GDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGR 734
BLAST of Dvl-2 vs. Ensembl Fly
Match: baz (gene:FBgn0000163 transcript:FBtr0343764) HSP 1 Score: 53.1434 bits (126), Expect = 1.757e-6 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 932 GDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQV-----QKPGPINLVVAK 1123
GD GI+V +++ GGA ++DGR+ D +L VN +S +N +A+ TLR + + PG I L+V +
Sbjct: 687 GDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGR 755
BLAST of Dvl-2 vs. Ensembl Fly
Match: baz (gene:FBgn0000163 transcript:FBtr0074388) HSP 1 Score: 53.1434 bits (126), Expect = 1.782e-6 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 932 GDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQV-----QKPGPINLVVAK 1123
GD GI+V +++ GGA ++DGR+ D +L VN +S +N +A+ TLR + + PG I L+V +
Sbjct: 666 GDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGR 734
BLAST of Dvl-2 vs. Ensembl Zebrafish
Match: dvl1a (dishevelled segment polarity protein 1a [Source:ZFIN;Acc:ZDB-GENE-090312-40]) HSP 1 Score: 210.69 bits (535), Expect = 9.515e-58 Identity = 94/126 (74.60%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+++FE+MSNDDAVR LRE V KPGPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A++
Sbjct: 90 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSG 215 HSP 2 Score: 154.066 bits (388), Expect = 1.100e-38 Identity = 79/163 (48.47%), Postives = 110/163 (67.48%), Query Frame = 2
Query: 1454 FFGYPMGMPGQFSQGAGSIV-TTSSSLPESERYQEELHLT-KNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
+F P P + A I TT+ S P ++L L+ TD+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWL+ +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L++ S +G LA LPPP
Sbjct: 189 YFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDG---LAPLPPP 348
BLAST of Dvl-2 vs. Ensembl Zebrafish
Match: dvl2 (dishevelled segment polarity protein 2 [Source:ZFIN;Acc:ZDB-GENE-041118-20]) HSP 1 Score: 213.772 bits (543), Expect = 1.576e-57 Identity = 96/127 (75.59%), Postives = 110/127 (86.61%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+GYFT+PR EP+RPIDP AWV H+ A+T
Sbjct: 249 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPQGYFTLPRNEPIRPIDPAAWVNHSVALTGA 375 HSP 2 Score: 155.221 bits (391), Expect = 2.101e-38 Identity = 71/135 (52.59%), Postives = 102/135 (75.56%), Query Frame = 2
Query: 1541 ERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLG---NTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
ER+ +E +L+ +D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++V+WLY HI+GF DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G N M+ LSL+ + S G + LA LP P
Sbjct: 394 ERF-DEFNLSLRSDMASVAKAMASPESGLEVRDRMWLKITIPNAFLGSDVVEWLYHHIDGFQDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDFSNCENYMANLSLNDNDGSS--GASDQDTLAPLPLP 525 HSP 3 Score: 135.191 bits (339), Expect = 5.849e-32 Identity = 57/80 (71.25%), Postives = 71/80 (88.75%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET+IIYHIDEEETPYL+K+ I+ +K+TL D K LN+P+YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV+++
Sbjct: 3 ETKIIYHIDEEETPYLVKIPIAAEKITLLDFKQVLNKPNYKFFFKSMDQDFGVVKEEISDDSAKLPCFNGRVVSWLVSSD 82
BLAST of Dvl-2 vs. Ensembl Zebrafish
Match: dvl3b (dishevelled segment polarity protein 3b [Source:ZFIN;Acc:ZDB-GENE-121101-2]) HSP 1 Score: 212.616 bits (540), Expect = 2.143e-57 Identity = 97/127 (76.38%), Postives = 108/127 (85.04%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDPNP+ FT+PR EP+RPIDP AWV HT AMT
Sbjct: 255 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPNPRSCFTLPRSEPIRPIDPAAWVSHTAAMTGA 381 HSP 2 Score: 168.318 bits (425), Expect = 9.434e-43 Identity = 74/134 (55.22%), Postives = 104/134 (77.61%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
E+ER+ E+ HL+ ++D+ + + ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY +EGF+DR+EARKYA+NLLK GYI+HTVNK+TFSEQCYY+ G+ NM+ L+L + S G + LA LP P
Sbjct: 407 ETERF-EDFHLSIHSDMAAVAKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHRVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGDVCGNMASLTLHDHDGSS--GASDQDTLAPLPHP 537 HSP 3 Score: 144.05 bits (362), Expect = 7.667e-35 Identity = 64/86 (74.42%), Postives = 75/86 (87.21%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSD 361
ET+IIYH+DE+ETPYLIKL I + VTL D KN LN+P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+A+GS SD
Sbjct: 3 ETKIIYHLDEQETPYLIKLPIPAENVTLADFKNVLNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSADGSHGSD 88
BLAST of Dvl-2 vs. Ensembl Zebrafish
Match: dvl1b (dishevelled segment polarity protein 1b [Source:ZFIN;Acc:ZDB-GENE-071004-1]) HSP 1 Score: 209.534 bits (532), Expect = 1.937e-56 Identity = 95/126 (75.40%), Postives = 108/126 (85.71%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V K GPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 241 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKNGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 366 HSP 2 Score: 154.066 bits (388), Expect = 4.231e-38 Identity = 86/174 (49.43%), Postives = 117/174 (67.24%), Query Frame = 2
Query: 1454 FFGYPMGMPGQFSQGAGSIVTTSS---SLPESERYQEELHLTK-NTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPI 1963
+F P P + A I T++ S P++E +EL LT TD+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG ++VDWLY +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L+ E S G + LA LPPP S+N P+
Sbjct: 340 YFTIPRAEPVRPIDPAAWISHTTALTGSYPQNEF--DELPLTMGKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGGDVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMATLNLN--EGSSGAG-SEQDTLAPLPPP--STNPWPM 506 HSP 3 Score: 138.272 bits (347), Expect = 4.702e-33 Identity = 64/85 (75.29%), Postives = 73/85 (85.88%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KLS++P+KVTL D KN L NRP YK+FFKSMD DFGVVKEE++DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETKIIYHIDEEETPYLVKLSVAPEKVTLADFKNVLSNRPVNSYKFFFKSMDQDFGVVKEEVSDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Zebrafish
Match: dvl1b (dishevelled segment polarity protein 1b [Source:ZFIN;Acc:ZDB-GENE-071004-1]) HSP 1 Score: 209.534 bits (532), Expect = 2.376e-56 Identity = 95/126 (75.40%), Postives = 108/126 (85.71%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V K GPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 250 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKNGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 375 HSP 2 Score: 154.066 bits (388), Expect = 4.902e-38 Identity = 86/174 (49.43%), Postives = 117/174 (67.24%), Query Frame = 2
Query: 1454 FFGYPMGMPGQFSQGAGSIVTTSS---SLPESERYQEELHLTK-NTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPI 1963
+F P P + A I T++ S P++E +EL LT TD+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG ++VDWLY +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L+ E S G + LA LPPP S+N P+
Sbjct: 349 YFTIPRAEPVRPIDPAAWISHTTALTGSYPQNEF--DELPLTMGKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGGDVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMATLNLN--EGSSGAG-SEQDTLAPLPPP--STNPWPM 515 HSP 3 Score: 138.272 bits (347), Expect = 5.073e-33 Identity = 64/85 (75.29%), Postives = 73/85 (85.88%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KLS++P+KVTL D KN L NRP YK+FFKSMD DFGVVKEE++DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETKIIYHIDEEETPYLVKLSVAPEKVTLADFKNVLSNRPVNSYKFFFKSMDQDFGVVKEEVSDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Xenopus
Match: dvl1 (dishevelled segment polarity protein 1 [Source:NCBI gene;Acc:100144639]) HSP 1 Score: 212.616 bits (540), Expect = 2.730e-58 Identity = 96/127 (75.59%), Postives = 109/127 (85.83%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI+L VAKCWDP P+ YFTIPR EPVRPIDP AW+ HT+A+T
Sbjct: 249 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWITHTSALTGA 375 HSP 2 Score: 159.073 bits (401), Expect = 3.900e-40 Identity = 74/135 (54.81%), Postives = 104/135 (77.04%), Query Frame = 2
Query: 1532 PESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
PESE+ QE+ L+ +D+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY H+EGF +R+EARKYA+++LK GY++HTVNK+TFSEQCYYV G+ N++ L+L++ S G + LA LP P
Sbjct: 400 PESEK-QEDSPLSVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNVAALNLNEGSS----GTSDQDTLAPLPHP 529 HSP 3 Score: 137.887 bits (346), Expect = 3.247e-33 Identity = 65/85 (76.47%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KL + P+KVTL D KN L NRP HYK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHHYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Xenopus
Match: dvl1 (dishevelled segment polarity protein 1 [Source:NCBI gene;Acc:100144639]) HSP 1 Score: 212.231 bits (539), Expect = 2.817e-57 Identity = 96/127 (75.59%), Postives = 109/127 (85.83%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI+L VAKCWDP P+ YFTIPR EPVRPIDP AW+ HT+A+T
Sbjct: 234 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWITHTSALTGA 360 HSP 2 Score: 158.688 bits (400), Expect = 1.518e-39 Identity = 74/135 (54.81%), Postives = 104/135 (77.04%), Query Frame = 2
Query: 1532 PESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
PESE+ QE+ L+ +D+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY H+EGF +R+EARKYA+++LK GY++HTVNK+TFSEQCYYV G+ N++ L+L++ S G + LA LP P
Sbjct: 385 PESEK-QEDSPLSVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNVAALNLNEGSS----GTSDQDTLAPLPHP 514 HSP 3 Score: 139.428 bits (350), Expect = 2.530e-33 Identity = 66/85 (77.65%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ETRIIYHIDEEETPYL+KL + P+KVTL D KN L NRP HYK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETRIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHHYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Xenopus
Match: dvl1 (dishevelled segment polarity protein 1 [Source:NCBI gene;Acc:100144639]) HSP 1 Score: 212.231 bits (539), Expect = 4.266e-57 Identity = 96/127 (75.59%), Postives = 109/127 (85.83%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI+L VAKCWDP P+ YFTIPR EPVRPIDP AW+ HT+A+T
Sbjct: 249 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWITHTSALTGA 375 HSP 2 Score: 159.073 bits (401), Expect = 1.590e-39 Identity = 74/135 (54.81%), Postives = 104/135 (77.04%), Query Frame = 2
Query: 1532 PESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
PESE+ QE+ L+ +D+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY H+EGF +R+EARKYA+++LK GY++HTVNK+TFSEQCYYV G+ N++ L+L++ S G + LA LP P
Sbjct: 400 PESEK-QEDSPLSVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNVAALNLNEGSS----GTSDQDTLAPLPHP 529 HSP 3 Score: 138.272 bits (347), Expect = 7.856e-33 Identity = 65/85 (76.47%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KL + P+KVTL D KN L NRP HYK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHHYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Xenopus
Match: dvl3 (dishevelled segment polarity protein 3 [Source:NCBI gene;Acc:100144702]) HSP 1 Score: 207.994 bits (528), Expect = 5.005e-56 Identity = 95/126 (75.40%), Postives = 107/126 (84.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND +FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+ FT+PR EP+RPIDP AWV HT AMT
Sbjct: 218 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRNCFTLPRSEPIRPIDPAAWVSHTAAMTG 343 HSP 2 Score: 160.999 bits (406), Expect = 2.055e-40 Identity = 72/128 (56.25%), Postives = 101/128 (78.91%), Query Frame = 2
Query: 1553 EELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ L+ ++D+ TI++ + P+SGL++RDR+WLKIT+PNAFIGS++VDWLY H+EGF+DR+EARKYA+NLLK GYI+HTVNK+TFSEQCYY+ G+ +M+ LSL+ + S G + LA LP P
Sbjct: 351 DDFQLSIHSDMVTIVKAMRSPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHHVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGD-LCDMANLSLNDHDGSS--GTSDQDTLAPLPHP 475 HSP 3 Score: 144.05 bits (362), Expect = 6.600e-35 Identity = 64/103 (62.14%), Postives = 82/103 (79.61%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLP 412
ET++IYH+DE+ETPYL+KL + +KVTLGD KN LN+P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+ WLV+A+GS D+ + N+S + P
Sbjct: 3 ETKVIYHLDEQETPYLVKLPVPAEKVTLGDFKNVLNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVCWLVSADGS----QSDAGSVCADNQSDLPP 101
BLAST of Dvl-2 vs. Ensembl Xenopus
Match: dvl3 (dishevelled segment polarity protein 3 [Source:NCBI gene;Acc:100144702]) HSP 1 Score: 208.379 bits (529), Expect = 7.743e-56 Identity = 95/126 (75.40%), Postives = 107/126 (84.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND +FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+ FT+PR EP+RPIDP AWV HT AMT
Sbjct: 244 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRNCFTLPRSEPIRPIDPAAWVSHTAAMTG 369 HSP 2 Score: 169.474 bits (428), Expect = 7.034e-43 Identity = 76/134 (56.72%), Postives = 106/134 (79.10%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
E+ER+ ++ L+ ++D+ TI++ + P+SGL++RDR+WLKIT+PNAFIGS++VDWLY H+EGF+DR+EARKYA+NLLK GYI+HTVNK+TFSEQCYY+ G+ NM+ LSL+ + S G + LA LP P
Sbjct: 396 ETERF-DDFQLSIHSDMVTIVKAMRSPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHHVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGDLCGNMANLSLNDHDGSS--GTSDQDTLAPLPHP 526 HSP 3 Score: 144.436 bits (363), Expect = 9.062e-35 Identity = 64/103 (62.14%), Postives = 82/103 (79.61%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLP 412
ET++IYH+DE+ETPYL+KL + +KVTLGD KN LN+P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+ WLV+A+GS D+ + N+S + P
Sbjct: 3 ETKVIYHLDEQETPYLVKLPVPAEKVTLGDFKNVLNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVCWLVSADGS----QSDAGSVCADNQSDLPP 101
BLAST of Dvl-2 vs. Ensembl Mouse
Match: Dvl3 (dishevelled segment polarity protein 3 [Source:MGI Symbol;Acc:MGI:108100]) HSP 1 Score: 211.075 bits (536), Expect = 9.419e-57 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+I+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 245 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTG 370 HSP 2 Score: 163.696 bits (413), Expect = 3.573e-41 Identity = 73/134 (54.48%), Postives = 105/134 (78.36%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ER ++ HL+ ++D+ I++ ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY ++EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ NM+ LSL + S G + LA LP P
Sbjct: 397 DTERL-DDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS--GASDQDTLAPLPHP 527 HSP 3 Score: 136.346 bits (342), Expect = 2.434e-32 Identity = 59/82 (71.95%), Postives = 70/82 (85.37%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+D +ETPYL+KL + ++VTL D K L RP YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+AEGS
Sbjct: 3 ETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGS 84
BLAST of Dvl-2 vs. Ensembl Mouse
Match: Dvl3 (dishevelled segment polarity protein 3 [Source:MGI Symbol;Acc:MGI:108100]) HSP 1 Score: 210.69 bits (535), Expect = 1.024e-56 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+I+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 245 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTG 370 HSP 2 Score: 164.081 bits (414), Expect = 3.125e-41 Identity = 73/134 (54.48%), Postives = 105/134 (78.36%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ER ++ HL+ ++D+ I++ ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY ++EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ NM+ LSL + S G + LA LP P
Sbjct: 397 DTERL-DDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS--GASDQDTLAPLPHP 527 HSP 3 Score: 136.346 bits (342), Expect = 2.286e-32 Identity = 59/82 (71.95%), Postives = 70/82 (85.37%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+D +ETPYL+KL + ++VTL D K L RP YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+AEGS
Sbjct: 3 ETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGS 84
BLAST of Dvl-2 vs. Ensembl Mouse
Match: Dvl2 (dishevelled segment polarity protein 2 [Source:MGI Symbol;Acc:MGI:106613]) HSP 1 Score: 206.068 bits (523), Expect = 4.807e-55 Identity = 94/134 (70.15%), Postives = 111/134 (82.84%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSS 1252
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+ YFT+PR EP++PIDP AWV H+ A+T P S
Sbjct: 263 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGAFPAYPGS 396 HSP 2 Score: 149.058 bits (375), Expect = 2.401e-36 Identity = 63/111 (56.76%), Postives = 89/111 (80.18%), Query Frame = 2
Query: 1505 SIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
S +T+ SSLP+ E L+ + D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF +R+EARKYA+ LLK G I+HTVNK+TFSEQCYYV G+
Sbjct: 400 STITSGSSLPDG---CEGRGLSVHMDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGD 507 HSP 3 Score: 126.331 bits (316), Expect = 3.992e-29 Identity = 53/81 (65.43%), Postives = 69/81 (85.19%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET++IYH+DEEETPYL+K+ + +++TLGD K+ L RP KYFFKSMD DFGVVKEEI+DD A+LPCF GRV+SWLV+++
Sbjct: 13 ETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSD 93
BLAST of Dvl-2 vs. Ensembl Mouse
Match: Dvl2 (dishevelled segment polarity protein 2 [Source:MGI Symbol;Acc:MGI:106613]) HSP 1 Score: 206.068 bits (523), Expect = 4.807e-55 Identity = 94/134 (70.15%), Postives = 111/134 (82.84%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSS 1252
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+ YFT+PR EP++PIDP AWV H+ A+T P S
Sbjct: 263 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGAFPAYPGS 396 HSP 2 Score: 149.058 bits (375), Expect = 2.401e-36 Identity = 63/111 (56.76%), Postives = 89/111 (80.18%), Query Frame = 2
Query: 1505 SIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
S +T+ SSLP+ E L+ + D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF +R+EARKYA+ LLK G I+HTVNK+TFSEQCYYV G+
Sbjct: 400 STITSGSSLPDG---CEGRGLSVHMDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGD 507 HSP 3 Score: 126.331 bits (316), Expect = 3.992e-29 Identity = 53/81 (65.43%), Postives = 69/81 (85.19%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET++IYH+DEEETPYL+K+ + +++TLGD K+ L RP KYFFKSMD DFGVVKEEI+DD A+LPCF GRV+SWLV+++
Sbjct: 13 ETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSD 93
BLAST of Dvl-2 vs. Ensembl Mouse
Match: Dvl2 (dishevelled segment polarity protein 2 [Source:MGI Symbol;Acc:MGI:106613]) HSP 1 Score: 206.068 bits (523), Expect = 4.807e-55 Identity = 94/134 (70.15%), Postives = 111/134 (82.84%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSS 1252
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+ YFT+PR EP++PIDP AWV H+ A+T P S
Sbjct: 263 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGAFPAYPGS 396 HSP 2 Score: 149.058 bits (375), Expect = 2.401e-36 Identity = 63/111 (56.76%), Postives = 89/111 (80.18%), Query Frame = 2
Query: 1505 SIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
S +T+ SSLP+ E L+ + D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF +R+EARKYA+ LLK G I+HTVNK+TFSEQCYYV G+
Sbjct: 400 STITSGSSLPDG---CEGRGLSVHMDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGD 507 HSP 3 Score: 126.331 bits (316), Expect = 3.992e-29 Identity = 53/81 (65.43%), Postives = 69/81 (85.19%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET++IYH+DEEETPYL+K+ + +++TLGD K+ L RP KYFFKSMD DFGVVKEEI+DD A+LPCF GRV+SWLV+++
Sbjct: 13 ETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSD 93
BLAST of Dvl-2 vs. UniProt/SwissProt
Match: sp|P51140|DSH_DROME (Segment polarity protein dishevelled OS=Drosophila melanogaster OX=7227 GN=dsh PE=1 SV=2) HSP 1 Score: 226.868 bits (577), Expect = 5.089e-62 Identity = 104/129 (80.62%), Postives = 116/129 (89.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGAS 1237
LNI+TV +NM+ V FLGISIVGQSN+GGDGGIYVGSIMKGGAVA DGRIEPGDMIL+VND++FE+M+ND+AVR LRE VQKPGPI LVVAKCWDPNPKGYFTIPR EPVRPIDP AWV HT A+T+ S
Sbjct: 248 LNIITVSINMEAVNFLGISIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPGPIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALTSHDS 376 HSP 2 Score: 122.479 bits (306), Expect = 2.692e-27 Identity = 57/89 (64.04%), Postives = 69/89 (77.53%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPH--YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDN 364
ET++IYHID+E TPYL+K+ I +VTL D K LN+ + YKYFFKSMD DFGVVKEEI DD LPCF GRV+SWLV+A+G+ SDN
Sbjct: 10 ETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLNKQNNNYKYFFKSMDADFGVVKEEIADDSTILPCFNGRVVSWLVSADGTNQSDN 98 HSP 3 Score: 119.013 bits (297), Expect = 3.239e-26 Identity = 47/80 (58.75%), Postives = 68/80 (85.00%), Query Frame = 2
Query: 1592 ILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVL 1831
I++ +++PDSGL+IRDR+WLKIT+PNAFIG++ V+W+ ++E DR+EAR+ + +L+ YIKHTVNK+TFSEQCYYV+
Sbjct: 397 IVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYIKHTVNKLTFSEQCYYVV 476
BLAST of Dvl-2 vs. UniProt/SwissProt
Match: sp|Q61062|DVL3_MOUSE (Segment polarity protein dishevelled homolog DVL-3 OS=Mus musculus OX=10090 GN=Dvl3 PE=1 SV=2) HSP 1 Score: 210.69 bits (535), Expect = 7.165e-56 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+I+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 245 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTG 370 HSP 2 Score: 164.081 bits (414), Expect = 2.186e-40 Identity = 73/134 (54.48%), Postives = 105/134 (78.36%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ER ++ HL+ ++D+ I++ ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY ++EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ NM+ LSL + S G + LA LP P
Sbjct: 397 DTERL-DDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS--GASDQDTLAPLPHP 527 HSP 3 Score: 136.346 bits (342), Expect = 1.599e-31 Identity = 59/82 (71.95%), Postives = 70/82 (85.37%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+D +ETPYL+KL + ++VTL D K L RP YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+AEGS
Sbjct: 3 ETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGS 84
BLAST of Dvl-2 vs. UniProt/SwissProt
Match: sp|Q92997|DVL3_HUMAN (Segment polarity protein dishevelled homolog DVL-3 OS=Homo sapiens OX=9606 GN=DVL3 PE=1 SV=2) HSP 1 Score: 210.69 bits (535), Expect = 8.246e-56 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VN+I+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 245 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTG 370 HSP 2 Score: 163.696 bits (413), Expect = 2.349e-40 Identity = 73/134 (54.48%), Postives = 105/134 (78.36%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
++ER ++ HL+ ++D+ I++ ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWLY ++EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ NM+ LSL + S G + LA LP P
Sbjct: 397 DTERL-DDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS--GASDQDTLAPLPHP 527 HSP 3 Score: 136.346 bits (342), Expect = 1.731e-31 Identity = 59/82 (71.95%), Postives = 70/82 (85.37%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYH+D +ETPYL+KL + ++VTL D K L RP YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+AEGS
Sbjct: 3 ETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGS 84
BLAST of Dvl-2 vs. UniProt/SwissProt
Match: sp|B1WAP7|DVL3_XENTR (Segment polarity protein dishevelled homolog DVL-3 OS=Xenopus tropicalis OX=8364 GN=dvl3 PE=2 SV=1) HSP 1 Score: 208.379 bits (529), Expect = 4.102e-55 Identity = 95/126 (75.40%), Postives = 107/126 (84.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND +FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+ FT+PR EP+RPIDP AWV HT AMT
Sbjct: 244 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRNCFTLPRSEPIRPIDPAAWVSHTAAMTG 369 HSP 2 Score: 169.474 bits (428), Expect = 3.727e-42 Identity = 76/134 (56.72%), Postives = 106/134 (79.10%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
E+ER+ ++ L+ ++D+ TI++ + P+SGL++RDR+WLKIT+PNAFIGS++VDWLY H+EGF+DR+EARKYA+NLLK GYI+HTVNK+TFSEQCYY+ G+ NM+ LSL+ + S G + LA LP P
Sbjct: 396 ETERF-DDFQLSIHSDMVTIVKAMRSPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHHVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGDLCGNMANLSLNDHDGSS--GTSDQDTLAPLPHP 526 HSP 3 Score: 144.436 bits (363), Expect = 4.801e-34 Identity = 64/103 (62.14%), Postives = 82/103 (79.61%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLP 412
ET++IYH+DE+ETPYL+KL + +KVTLGD KN LN+P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+ WLV+A+GS D+ + N+S + P
Sbjct: 3 ETKVIYHLDEQETPYLVKLPVPAEKVTLGDFKNVLNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVCWLVSADGS----QSDAGSVCADNQSDLPP 101
BLAST of Dvl-2 vs. UniProt/SwissProt
Match: sp|Q05AS8|DVL2_XENTR (Segment polarity protein dishevelled homolog DVL-2 OS=Xenopus tropicalis OX=8364 GN=dvl2 PE=2 SV=1) HSP 1 Score: 208.379 bits (529), Expect = 5.093e-55 Identity = 93/126 (73.81%), Postives = 110/126 (87.30%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LR+ V KPGPI L VAKCWDP+P+GYFT+PR EP++PIDP AWV H+ A++
Sbjct: 246 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLRDIVHKPGPIILTVAKCWDPSPQGYFTLPRNEPIQPIDPAAWVSHSAALSG 371 HSP 2 Score: 155.221 bits (391), Expect = 1.714e-37 Identity = 71/130 (54.62%), Postives = 99/130 (76.15%), Query Frame = 2
Query: 1565 LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTL---NMSRLSLDQVESVSEVGVNGPHHLAALPPPNFS 1945
L+ +TD+ ++ +V++ P+SGL++RDR+WLKIT+PNAF+GS++VDWLY H+EGF DR+EARK+A+NLLK G I+HTVNK+TFSEQCYY+ G+ T M+ LSL+ + S G + LA LP P S
Sbjct: 408 LSVHTDLASVAKVMASPESGLEVRDRMWLKITIPNAFLGSDMVDWLYHHVEGFQDRREARKFASNLLKAGLIRHTVNKITFSEQCYYIFGDLTGCENYMANLSLNDNDGSS--GASDQDTLAPLPLPGAS 535 HSP 3 Score: 127.102 bits (318), Expect = 1.454e-28 Identity = 54/82 (65.85%), Postives = 68/82 (82.93%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET++IYH+DEEETPYL+K+ + +++ L D K AL R H KYFFK+MD DFGVVKEEI+DD AKLPCF GRV+SWLV++E S
Sbjct: 3 ETKVIYHLDEEETPYLVKVPVPANEIRLRDFKAALGRGHAKYFFKAMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVSSETS 84
BLAST of Dvl-2 vs. TrEMBL
Match: F2WMR5 (Dvl-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1229.16 bits (3179), Expect = 0.000e+0 Identity = 773/775 (99.74%), Postives = 773/775 (99.74%), Query Frame = 2
Query: 65 MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESXXXXXXXXXXXSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPXXXXXXXXXXXXXXXQYSVVGPLPCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ 2389
MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKN LNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGP RSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPSNNANVATATASSNSQYSVVGPLPCSQPSQHASSNASASAIKKSGSCNSLSGSSSSTSSSSSSNRSNTRINGNASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ
Sbjct: 1 MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNTLNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPPRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPSNNANVATATASSNSQYSVVGPLPCSQPSQHASSNASASAIKKSGSCNSLSGSSSSTSSSSSSNRSNTRINGNASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ 775
BLAST of Dvl-2 vs. TrEMBL
Match: B1NWV9 (Dishevelled-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=Dvl-b PE=2 SV=1) HSP 1 Score: 913.294 bits (2359), Expect = 0.000e+0 Identity = 543/545 (99.63%), Postives = 543/545 (99.63%), Query Frame = 2
Query: 170 PDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESXXXXXXXXXXXSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT 1804
PDKVTLGDLKN LNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGP RSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT
Sbjct: 1 PDKVTLGDLKNTLNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPPRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT 545
BLAST of Dvl-2 vs. TrEMBL
Match: D3J1K0 (Dishevelled (Fragment) OS=Schmidtea polychroa OX=50054 GN=dvl PE=2 SV=1) HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0 Identity = 317/318 (99.69%), Postives = 317/318 (99.69%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT 1804
LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPG SVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT
Sbjct: 216 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGTSVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVT 533 HSP 2 Score: 308.145 bits (788), Expect = 9.140e-90 Identity = 159/162 (98.15%), Postives = 159/162 (98.15%), Query Frame = 2
Query: 170 PDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESXXXXXXXXXXXSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETN 655
PDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDN DSNGILDKNESRMLPFQESHFPL NNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNG NPIYETN
Sbjct: 1 PDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNADSNGILDKNESRMLPFQESHFPLTNNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGPNPIYETN 162
BLAST of Dvl-2 vs. TrEMBL
Match: A0A4Z2DKF8 (Putative Dishevelled segment polarity protein DVL-3 OS=Schistosoma japonicum OX=6182 GN=EWB00_000072 PE=4 SV=1) HSP 1 Score: 535.798 bits (1379), Expect = 1.289e-170 Identity = 355/670 (52.99%), Postives = 422/670 (62.99%), Query Frame = 2
Query: 89 NVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSD---------------------NVDSNGILDKNESR----MLPFQESHFPLINNIKASGGTTTNESXXXXXXXXXXXSVYSAAQDRVGPLRSF--------HDYKQAG--RVAAHANRVNTNTPN----GQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNP-KGYFTIPRQEPVRPIDPRAWVLHTNAMT-----AGASEPPSSVNG--------------------VHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVN 1903
N ET+ IY+IDEEETPYL+KL+I+P+KVTLGD KNALNRPH K+FFKS+DDDFGVVKEEI +D A LPCF GRVISWLVTAE S SD N+D +NE + +L + P ++ A+ G N SV+SA QDR+ PLR+F H Y G + AN N+ + + YET S M S ++ E+ S S T T S RY R +++RRRRRPP ISRASSFSSITDSTMSLNIV+V LNMDTV FLGISIVGQSNK GDGGIYVGSIMKGGAVAQDGRIEPGDMILE N ISFE+MSNDDAVRTLREQVQ+PGPI LVVAKCWDPNP + YFTIPRQEPV PIDPRAWVLHTNAMT A +P VNG + P +S S Q+ + GT A + A AA+ Q + P S P G Q A SIVT SSSLPE ERY + + L+ +T + T++R + QPDSGLDIRDR+WLK+T+PNAFIGS+LVDWL+RH+EG +DR+EARKYA+NLLK GYI+H VNK+TFSEQCYYV + + MS LSL++V+SVSEVG +
Sbjct: 5 NSFVGETKFIYYIDEEETPYLVKLNIAPEKVTLGDFKNALNRPHSKFFFKSLDDDFGVVKEEIFEDNAPLPCFNGRVISWLVTAEESIASDPGVLSPSIETNTNANNNKYPPNLDLESSNTRNECKGSSCVLQPHTTAAP-ADSTSANLGHGRNTGQNYDTETE---SVHSANQDRIAPLRNFHHYKSSGRHHYTMGGSSHLVQQANHNNSRHRHYRHLASSSTYETPSMMSSDLESTSFLDSEEESSRFSSVTGTTLSSRRYSRARRRRRRRRPPPISRASSFSSITDSTMSLNIVSVTLNMDTVNFLGISIVGQSNKSGDGGIYVGSIMKGGAVAQDGRIEPGDMILEANGISFEEMSNDDAVRTLREQVQRPGPITLVVAKCWDPNPAERYFTIPRQEPVHPIDPRAWVLHTNAMTTPDSHAQGGDPHRHVNGASMTGASSGGESSSTLSPPGLTPGMSMGTLTSGQTSMPLGTSAAAFNMAALLAASKQKQEQELQQQNLLQQRIHLSQPTCYSASNMLLPHGYTQQI---APSIVTVSSSLPEIERYSDPIPLSLSTSIPTVIRAMLQPDSGLDIRDRVWLKLTVPNAFIGSDLVDWLFRHLEGLTDRREARKYASNLLKLGYIRHIVNKLTFSEQCYYVFRDISERMSCLSLEEVDSVSEVGAH 667
BLAST of Dvl-2 vs. TrEMBL
Match: A0A5K4EAL9 (Putative dishevelled OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 528.48 bits (1360), Expect = 5.685e-169 Identity = 366/704 (51.99%), Postives = 445/704 (63.21%), Query Frame = 2
Query: 101 DETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLIN----NIKASGGT-----------TTNESXXXXXXXXXXXSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQ---PQNI---------NQNTASVSTVGGPPG---------ASVGFFGYPMGMPGQFSQGAGSIVTTSS---SLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNG--------------PHHLAALPPPNFSSNKQPISSCINQ--PPLNINPQLTATSEPLP 2032
D+T+IIYHID+EETPYL+K+++ P+ VTLGD KNALNRP+YK+FFKS+D DFGVVKEEI DD+A+LPCF G+VISWLV+A+ ST SDN S G + + LP Q + N NI + TT CDTC +TDSVYS DRV PL++FH+YK R+A R+ QN YET+SSMMSSDLESTSFFDSEDESSRFST T TTMSS + +++RR R A+SFSS+TDSTMSLNI+TV LNMD+V FLGISIVGQSNK GDGGIYVGSIM+GGAVAQDGRIEPGDMILEVN ISFEDMSND+AVR LRE+VQKPGPI LVVAKCWDP+PK YFTIPRQEPVRPIDPRAWVLHTNAMT P +G P + + +++ G M S+ + MP P ++ N T S+ V G AS G G P S+ G + SL + LT +D+ +++ + DSGL+IRDR WLKIT+PNAFIGS LVDWL+ H++GF+DR++AR+YA+NLL +GYI HTVNK TFSEQCYY G+ +S L+LD+V+SVSE+G N PH LP S + +SS NQ PP NP L S P+P
Sbjct: 2 DDTKIIYHIDDEETPYLVKIAVCPNAVTLGDFKNALNRPNYKFFFKSVDADFGVVKEEIADDDARLPCFNGKVISWLVSADSSTKSDN-HSTGTGENH----LPGQNKNSTNFNKAPDNIHSVSKNEIPSEQEHAIGTTGHGLEECDTCVETDSVYSG--DRVPPLKNFHNYKHGSRLAKLGQRI-------QN--YETSSSMMSSDLESTSFFDSEDESSRFSTATGTTMSSAKYPRHRRQRRHRRILPIRRTSEDATSFSSVTDSTMSLNIITVTLNMDSVNFLGISIVGQSNKAGDGGIYVGSIMRGGAVAQDGRIEPGDMILEVNRISFEDMSNDEAVRVLREEVQKPGPITLVVAKCWDPSPKNYFTIPRQEPVRPIDPRAWVLHTNAMTGALGTP--GFDGNTPFFGSGSPAAGMAMIPGHFMGMTPSSGLSVPSMPPGMPPLILPPSMAGINAIPSSNMTTKSLPEVADGDGGGYHRSRGPASSGVVGGPGSTKTNGSRSGGETTVDAKGTQSLLSGANGKSSTSLTVASDMASVVHDMLMSDSGLEIRDRTWLKITIPNAFIGSELVDWLFTHVDGFADRRDARRYASNLLHYGYICHTVNKSTFSEQCYYTFGDIATTLSHLNLDEVDSVSEIGANSSSHTGTHPMMPQMYPHVHHVLPDAPGSGSATGLSSVQNQNAPP---NPNLGLMSSPIP 684
BLAST of Dvl-2 vs. Ensembl Cavefish
Match: dvl2 (dishevelled segment polarity protein 2 [Source:NCBI gene;Acc:103045219]) HSP 1 Score: 214.157 bits (544), Expect = 1.011e-57 Identity = 96/126 (76.19%), Postives = 110/126 (87.30%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+GYFT+PR EP+RPIDP AWV H+ A+T
Sbjct: 252 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPQGYFTLPRNEPIRPIDPAAWVSHSVALTG 377 HSP 2 Score: 154.451 bits (389), Expect = 3.393e-38 Identity = 69/131 (52.67%), Postives = 101/131 (77.10%), Query Frame = 2
Query: 1553 EELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTL---NMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
+E +L+ ++D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++V+WLY HIEGF DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYY+ G+ + M+ LSL+ + S G + LA LP P
Sbjct: 400 DEFNLSLHSDMASVAKAMASPESGLEVRDRMWLKITIPNAFLGSDVVEWLYHHIEGFQDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDFSDCENYMANLSLNDNDGSS--GASDQDTLAPLPLP 528 HSP 3 Score: 134.035 bits (336), Expect = 1.270e-31 Identity = 57/80 (71.25%), Postives = 70/80 (87.50%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET+IIYHIDEEETPYL+K+ I +K+TL D K LN+P+YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV+++
Sbjct: 3 ETKIIYHIDEEETPYLVKIPIPAEKITLLDFKQVLNKPNYKFFFKSMDQDFGVVKEEISDDSAKLPCFNGRVVSWLVSSD 82
BLAST of Dvl-2 vs. Ensembl Cavefish
Match: dvl1a (segment polarity protein dishevelled homolog DVL-1 [Source:NCBI gene;Acc:103035729]) HSP 1 Score: 213.772 bits (543), Expect = 1.041e-57 Identity = 96/126 (76.19%), Postives = 109/126 (86.51%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 251 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 376 HSP 2 Score: 146.747 bits (369), Expect = 8.401e-36 Identity = 65/121 (53.72%), Postives = 90/121 (74.38%), Query Frame = 2
Query: 1574 NTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
TD+ TI +V+ P+SGL+IRDR+WLKIT+ NA IG+++VDWL+ +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L++ S +A LPPP
Sbjct: 392 KTDMATIAKVMQLPESGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGGSEQDT--VAPLPPP 510 HSP 3 Score: 136.732 bits (343), Expect = 1.593e-32 Identity = 66/89 (74.16%), Postives = 75/89 (84.27%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNAL-NRP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSD 361
ET+IIYH+DEEETPYL+KLS+SPD+VTL D K+ L NRP YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV E ST SD
Sbjct: 3 ETKIIYHVDEEETPYLVKLSVSPDRVTLADFKHVLSNRPTNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLTE-STHSD 90
BLAST of Dvl-2 vs. Ensembl Cavefish
Match: dvl1b (segment polarity protein dishevelled homolog DVL-1-like [Source:NCBI gene;Acc:103046093]) HSP 1 Score: 209.92 bits (533), Expect = 1.750e-56 Identity = 95/126 (75.40%), Postives = 108/126 (85.71%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V K GPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 247 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKTGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 372 HSP 2 Score: 149.058 bits (375), Expect = 1.869e-36 Identity = 79/172 (45.93%), Postives = 113/172 (65.70%), Query Frame = 2
Query: 1454 FFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQ-EELHLT-KNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPI 1963
+F P P + A I T++ +Y+ ++L LT TD+ T+++V+ PDSGL+IRDR+WLKIT+ NA IG ++VDWLY +EGF DR++ARKYA+ +LK GY++HTVNK+TFSEQCYY G+ NM+ L+L++ S G + LA LPP S+N P+
Sbjct: 346 YFTIPRAEPVRPIDPAAWISHTTALTGSYPQYEFDDLPLTVGKTDMATLVKVMQLPDSGLEIRDRMWLKITIANAVIGGDVVDWLYSRVEGFKDRRDARKYASTMLKHGYLRHTVNKITFSEQCYYTFGDICQNMASLNLNE---GSSGGGSEQDTLAPLPP---STNPWPM 511 HSP 3 Score: 138.658 bits (348), Expect = 3.969e-33 Identity = 65/85 (76.47%), Postives = 72/85 (84.71%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALN-RP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KL ++PDKVTL D KN LN RP YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE S
Sbjct: 3 ETKIIYHIDEEETPYLVKLPVAPDKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESS 87
BLAST of Dvl-2 vs. Ensembl Cavefish
Match: dvl3a (segment polarity protein dishevelled homolog DVL-3-like [Source:NCBI gene;Acc:103042896]) HSP 1 Score: 206.453 bits (524), Expect = 1.228e-55 Identity = 93/126 (73.81%), Postives = 106/126 (84.13%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+M NDDAVR LR+ V KPGP++L VAKCWDPNP F +PR EP+RPIDP AWV HT AMT
Sbjct: 246 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMCNDDAVRVLRDIVHKPGPVSLTVAKCWDPNPNSCFALPRSEPIRPIDPAAWVSHTAAMTG 371 HSP 2 Score: 170.244 bits (430), Expect = 1.434e-43 Identity = 76/136 (55.88%), Postives = 109/136 (80.15%), Query Frame = 2
Query: 1466 PMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQ 1873
P GM S + + SSS+PE+ER+ ++ HL+ ++D+ T+ + ++ PDSGL++RDR+WLKIT+ NAFIGS++VDWL+ H+EGF+DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYYV G+ + NM+ LSL +
Sbjct: 375 PYGMSPSMSTVTSTSSSISSSIPETERF-DDYHLSVHSDMATVAKAMACPDSGLEVRDRMWLKITIANAFIGSDVVDWLFHHVEGFADRREARKYASNLLKAGFIRHTVNKITFSEQCYYVFGDLSGNMAHLSLHE 509 HSP 3 Score: 139.813 bits (351), Expect = 1.058e-33 Identity = 58/82 (70.73%), Postives = 75/82 (91.46%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET++IYH+DE+ETPYL+KL++ ++VTL DLKNAL +P++K+FFKSMDDDFGVVKEEITDD AKLPC+ GRV+ WLV+A+GS
Sbjct: 3 ETKVIYHLDEQETPYLVKLAVPAERVTLSDLKNALKKPNHKFFFKSMDDDFGVVKEEITDDNAKLPCYNGRVVCWLVSADGS 84
BLAST of Dvl-2 vs. Ensembl Cavefish
Match: dvl3b (dishevelled segment polarity protein 3b [Source:ZFIN;Acc:ZDB-GENE-121101-2]) HSP 1 Score: 196.438 bits (498), Expect = 2.515e-52 Identity = 89/113 (78.76%), Postives = 98/113 (86.73%), Query Frame = 2
Query: 893 FLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDPNP+G FT+PR EP+RPIDP AWV HT AMT
Sbjct: 240 LLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPNPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGA 352 HSP 2 Score: 173.326 bits (438), Expect = 1.083e-44 Identity = 77/134 (57.46%), Postives = 106/134 (79.10%), Query Frame = 2
Query: 1535 ESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
E+ER+ EE HL+ ++D+ TI + ++ P+SGL++RDR+WLKIT+PNAFIGS++VDWL+ H+EGF+DR+EARKYA+NLLK GYI+HTVNK+TFSEQCYY+ G+ NM+ L+L + S G + LA LP P
Sbjct: 378 ETERF-EEFHLSIHSDMATIAKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLFHHVEGFTDRREARKYASNLLKAGYIRHTVNKITFSEQCYYIFGDLCGNMANLTLHDHDGSS--GASDQDTLAPLPHP 508 HSP 3 Score: 142.124 bits (357), Expect = 1.728e-34 Identity = 63/98 (64.29%), Postives = 80/98 (81.63%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNE 397
ET+IIYH+D++ETPYL+KL I ++VTL D K+ LN+P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+A+GS SD + G + E
Sbjct: 3 ETKIIYHLDDQETPYLVKLPIPAERVTLADFKHVLNKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSADGSHGSDGGSACGAESQAE 100
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001371.1 (pep scaffold:Pmarinus_7.0:GL492828:1505:4356:1 gene:ENSPMAG00000001236.1 transcript:ENSPMAT00000001371.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 154.066 bits (388), Expect = 1.500e-43 Identity = 67/129 (51.94%), Postives = 96/129 (74.42%), Query Frame = 2
Query: 1451 GFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGN 1837
G+F P P + A + T++ +ELHL+ ++D+ T+++ ++ P+SGL++RDR+WLKIT+PNAFIGS+LVDWL+ H+EGF DR++ARKYA NLLK G I+HTVNK+TFSEQCYY+ G+
Sbjct: 25 GYFTIPRSEPVRPIDPAAWVSHTAAMTGAYPYGFDELHLSIHSDMATVVKAMASPESGLEVRDRMWLKITIPNAFIGSDLVDWLFNHLEGFQDRRDARKYACNLLKAGLIRHTVNKITFSEQCYYIFGD 153 HSP 2 Score: 85.5001 bits (210), Expect = 1.370e-19 Identity = 38/72 (52.78%), Postives = 48/72 (66.67%), Query Frame = 2
Query: 1100 PINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLS 1315
PI L VAKCWDP P+GYFTIPR EPVRPIDP AWV HT AMT P + +H + + +A ++++ S
Sbjct: 10 PITLTVAKCWDPTPRGYFTIPRSEPVRPIDPAAWVSHTAAMTGAY---PYGFDELHLSIHSDMATVVKAMAS 78
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002205.1 (pep scaffold:Pmarinus_7.0:GL477144:51012:68257:1 gene:ENSPMAG00000001988.1 transcript:ENSPMAT00000002205.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.6842 bits (130), Expect = 9.706e-8 Identity = 34/82 (41.46%), Postives = 48/82 (58.54%), Query Frame = 2
Query: 896 LGISIVGQSNKGG--DGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQV----QKPGPINLVVAK 1123
LG+S+ G ++ G D GIYV SI+ GGA A+DGR+ GD ++ VN SN A+ TLR + + G I+L VA+
Sbjct: 527 LGVSVKGNRSRDGAHDLGIYVKSIIAGGAAAKDGRLRIGDQLVAVNREPLLGRSNAAAMETLRRCMATDGSERGRIHLAVAR 608
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008444.1 (pep scaffold:Pmarinus_7.0:GL479496:14395:17295:-1 gene:ENSPMAG00000007646.1 transcript:ENSPMAT00000008444.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 47.3654 bits (111), Expect = 5.260e-7 Identity = 25/71 (35.21%), Postives = 42/71 (59.15%), Query Frame = 2
Query: 119 YHIDEEETPYLIKLSISPDKVTLGDLKNALNRP-HYKYFFKSMDDDF--GVVKEEITDDEAKLPCFKGRVI 322
Y+ E PY + + D +TL K L + +Y+++FK ++F GVV EE+ DD+A LP ++G+V+
Sbjct: 14 YYFCGEPIPY--RSRVRGDSLTLAHFKELLTKKGNYRFYFKKASEEFECGVVFEEVRDDKALLPLYQGKVV 82
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009066.1 (pep scaffold:Pmarinus_7.0:GL479913:2065:18580:1 gene:ENSPMAG00000008193.1 transcript:ENSPMAT00000009066.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 50.8322 bits (120), Expect = 1.484e-6 Identity = 28/71 (39.44%), Postives = 40/71 (56.34%), Query Frame = 2
Query: 866 VRLNMDTVKFLGISIVGQSN-KGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTL 1075
V++N+ + LG SIV + + GIY+ SI+KGGA DGRI GD +L +N S +S AV +
Sbjct: 628 VQINLQKRQGLGFSIVAAKGPRQANIGIYIKSIIKGGAADLDGRIARGDQLLSINGTSLIGISEKRAVEIM 698
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006056.1 (pep scaffold:Pmarinus_7.0:GL477535:225:55869:1 gene:ENSPMAG00000005437.1 transcript:ENSPMAT00000006056.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 50.8322 bits (120), Expect = 1.601e-6 Identity = 30/82 (36.59%), Postives = 48/82 (58.54%), Query Frame = 2
Query: 896 LGISIVGQSNK--GGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQK----PGPINLVVAK 1123
LG+S+ G ++ D GI++ +I+ GGA A+DGR+ D ++ VN S SN +A+ +LR + + P I LVVA+
Sbjct: 553 LGVSVKGTKDRRTNADLGIFIKTIIAGGAAAKDGRLRVDDQLIAVNRESLLGRSNLEAMESLRCAMSRDAGDPSLIQLVVAR 634
BLAST of Dvl-2 vs. Ensembl Yeast
Match: IML1 (GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Iml1p functions in the SEACIT complex as a GAP for the Rag family GTPase Gtr1p (EGOC subunit), resulting in the inhibition of TORC1 signaling in response to amino acid deprivation; the Iml1p/SEACIT complex is required for non-nitrogen-starvation (NNS)-induced autophagy [Source:SGD;Acc:S000003899]) HSP 1 Score: 48.1358 bits (113), Expect = 7.474e-6 Identity = 22/87 (25.29%), Postives = 43/87 (49.43%), Query Frame = 2
Query: 1565 LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYY 1825
L +N ++ + + + + + + +R W F+GS +V+WL R+ R++A KY ++K G H +NK F + Y+
Sbjct: 1182 LNRNVELSKLAYQIQRGEDRITLVNRKWHWKKHEKCFVGSEMVNWLIRNFSDIDTREDAIKYGQKVMKEGLFVHVLNKHNFLDGHYF 1268
BLAST of Dvl-2 vs. Ensembl Nematostella
Match: EDO39599 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9L8]) HSP 1 Score: 212.616 bits (540), Expect = 1.485e-58 Identity = 96/130 (73.85%), Postives = 109/130 (83.85%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASE 1240
LNI+T+ LNMD V FLGISIVGQSNK GDGGIYVGS+MKGGAV DGR+EPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI L VAKCWDP PKGYFT+P +PVRPID AWV HT AM A++
Sbjct: 245 LNIITITLNMDKVNFLGISIVGQSNKKGDGGIYVGSVMKGGAVDLDGRVEPGDMLLQVNDVNFENMSNDDAVRVLREMVHKPGPITLTVAKCWDPTPKGYFTLPHSDPVRPIDTSAWVQHTTAMNQFAAQ 374 HSP 2 Score: 176.022 bits (445), Expect = 3.895e-46 Identity = 84/151 (55.63%), Postives = 109/151 (72.19%), Query Frame = 2
Query: 1532 PESERYQE---ELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALP-----PPNFSSNKQP 1960
PES+RY E LT NTD+ T+++ ++ PDSGLDIRDR+WLKIT+PNAFIGS++VDWLY H+EGF DR+EARKYA NLLK GYI+HTVNK+TFSEQCYYV G+ N++ LSL++ E + P A+P PP + ++ P
Sbjct: 405 PESDRYTEIPEGEALTINTDMSTVVKAMAAPDSGLDIRDRMWLKITIPNAFIGSDVVDWLYTHVEGFMDRREARKYACNLLKAGYIRHTVNKITFSEQCYYVFGDLCGNLAALSLNENEGDQDTLGPLPPQQQAIPWMTGGPPAYGYHQMP 555 HSP 3 Score: 147.517 bits (371), Expect = 7.685e-37 Identity = 64/90 (71.11%), Postives = 78/90 (86.67%), Query Frame = 2
Query: 101 DETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVD 370
DET++IYHID+E+TPYL+KL +PD VTLGD KN LNRP+YK+FFKSMDDDFGVVKEEI+DDE LPCF GRV++WLVT++ S+VS D
Sbjct: 2 DETKVIYHIDDEDTPYLVKLGKTPDIVTLGDFKNVLNRPNYKFFFKSMDDDFGVVKEEISDDETHLPCFNGRVVAWLVTSDTSSVSGGGD 91
BLAST of Dvl-2 vs. Ensembl Nematostella
Match: EDO39598 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9L7]) HSP 1 Score: 167.933 bits (424), Expect = 1.797e-42 Identity = 85/135 (62.96%), Postives = 98/135 (72.59%), Query Frame = 2
Query: 881 DTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGAS-------EPPSSVNGV 1264
D V FLGISIVGQSNK GDGGIYVGS+MKGGAV DGR+EPGDM+L+VND++FE+MSNDDAVR LRE V KPGPI L VAKCWDP PKGYFT+P + ID R + +M G + E PSS G+
Sbjct: 167 DKVNFLGISIVGQSNKKGDGGIYVGSVMKGGAVDLDGRVEPGDMLLQVNDVNFENMSNDDAVRVLREMVHKPGPITLTVAKCWDPTPKGYFTLPHKLLEVRID-RKITNWSGSMAIGVTTANPSMIEIPSSATGL 300
BLAST of Dvl-2 vs. Ensembl Nematostella
Match: EDO46059 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR65]) HSP 1 Score: 60.077 bits (144), Expect = 3.799e-10 Identity = 34/81 (41.98%), Postives = 52/81 (64.20%), Query Frame = 2
Query: 890 KFLGISIVGQSNKG---GDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAK 1123
K LG SI G S GD GIY+ I++GGA QDGR++ GD I+ VN + ED+S++DAV+ L+ ++ + +VV++
Sbjct: 109 KGLGFSIAGGSGNQHVPGDNGIYITKIIEGGAAQQDGRLQVGDKIISVNLQNLEDVSHEDAVQVLKATKER---VTIVVSR 186
BLAST of Dvl-2 vs. Ensembl Nematostella
Match: EDO45887 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRU6]) HSP 1 Score: 59.6918 bits (143), Expect = 5.607e-9 Identity = 45/141 (31.91%), Postives = 70/141 (49.65%), Query Frame = 2
Query: 866 VRLNMDTVKFLGISIVGQ---SNKGGDG----GIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQK----PGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSV 1255
+ LNM LG+S+ G+ ++ G D GI+V S++ GGA +DGR++ D +L VN++SF ++N +A+ LR +Q I VA+ DP T+ R V P+ + T EPP+SV
Sbjct: 429 IPLNMSGAAGLGVSVKGKVADTDSGRDSPIDMGIFVKSVIAGGAAFKDGRLKAEDQLLSVNNVSFMRLTNTEAIDGLRRAMQNTRLGQAFIETTVARERDPQ-NDIGTVVRSHEVLKAPPQERSIEGGDHTPTRVEPPTSV 568
BLAST of Dvl-2 vs. Ensembl Nematostella
Match: EDO37929 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEC9]) HSP 1 Score: 54.6842 bits (130), Expect = 1.133e-7 Identity = 20/52 (38.46%), Postives = 39/52 (75.00%), Query Frame = 2
Query: 179 VTLGDLKNALNRPH-YKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWL 331
+TL D K+ +RP Y++ FK++D +FG VKEE+ +D+ +P ++G++++W+
Sbjct: 294 ITLRDFKHMFDRPGPYRFHFKALDPEFGTVKEEVIEDDDIIPGWEGKIVAWV 345
BLAST of Dvl-2 vs. Ensembl Medaka
Match: dvl2 (dishevelled segment polarity protein 2 [Source:NCBI gene;Acc:101163770]) HSP 1 Score: 213.001 bits (541), Expect = 1.555e-57 Identity = 96/127 (75.59%), Postives = 111/127 (87.40%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+GYFT+PR EP+RPIDP AWV H+ A++ G
Sbjct: 239 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPIILTVAKCWDPSPQGYFTLPRNEPIRPIDPAAWVSHSVAVSGG 365 HSP 2 Score: 159.073 bits (401), Expect = 1.075e-39 Identity = 72/132 (54.55%), Postives = 105/132 (79.55%), Query Frame = 2
Query: 1541 ERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
ER+ ++ +L+ ++D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++V+WL+ HIEGF DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYYV G+ LNM+ LSL+ + S G + LA LP P
Sbjct: 388 ERF-DDFNLSLHSDMASVAKAMASPESGLEVRDRMWLKITIPNAFLGSDVVEWLFHHIEGFQDRREARKYASNLLKAGFIRHTVNKITFSEQCYYVFGD--LNMANLSLNDNDGSS--GASDQDTLAPLPLP 514 HSP 3 Score: 128.257 bits (321), Expect = 6.770e-30 Identity = 54/76 (71.05%), Postives = 66/76 (86.84%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWL 331
ET+IIYHIDEEETPYL+K+ I+ + +TL D K LN+P+YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SW+
Sbjct: 3 ETKIIYHIDEEETPYLVKIPIAAENITLLDFKQVLNKPNYKFFFKSMDQDFGVVKEEISDDSAKLPCFNGRVVSWV 78
BLAST of Dvl-2 vs. Ensembl Medaka
Match: dvl2 (dishevelled segment polarity protein 2 [Source:NCBI gene;Acc:101163770]) HSP 1 Score: 212.616 bits (540), Expect = 3.893e-57 Identity = 96/127 (75.59%), Postives = 111/127 (87.40%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAG 1231
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LRE V KPGPI L VAKCWDP+P+GYFT+PR EP+RPIDP AWV H+ A++ G
Sbjct: 253 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPIILTVAKCWDPSPQGYFTLPRNEPIRPIDPAAWVSHSVAVSGG 379 HSP 2 Score: 152.91 bits (385), Expect = 1.115e-37 Identity = 70/135 (51.85%), Postives = 104/135 (77.04%), Query Frame = 2
Query: 1541 ERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTL---NMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
ER+ ++ +L+ ++D+ ++ + ++ P+SGL++RDR+WLKIT+PNAF+GS++V+WL+ HIEGF DR+EARKYA+NLLK G+I+HTVNK+TFSEQCYYV G+ + M+ LSL+ + S G + LA LP P
Sbjct: 402 ERF-DDFNLSLHSDMASVAKAMASPESGLEVRDRMWLKITIPNAFLGSDVVEWLFHHIEGFQDRREARKYASNLLKAGFIRHTVNKITFSEQCYYVFGDLSDCENYMANLSLNDNDGSS--GASDQDTLAPLPLP 533 HSP 3 Score: 132.88 bits (333), Expect = 3.157e-31 Identity = 56/80 (70.00%), Postives = 70/80 (87.50%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAE 343
ET+IIYHIDEEETPYL+K+ I+ + +TL D K LN+P+YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV+++
Sbjct: 3 ETKIIYHIDEEETPYLVKIPIAAENITLLDFKQVLNKPNYKFFFKSMDQDFGVVKEEISDDSAKLPCFNGRVVSWLVSSD 82
BLAST of Dvl-2 vs. Ensembl Medaka
Match: dvl1a (dishevelled segment polarity protein 1 [Source:NCBI gene;Acc:101165393]) HSP 1 Score: 209.92 bits (533), Expect = 4.914e-57 Identity = 95/126 (75.40%), Postives = 108/126 (85.71%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V K GPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 207 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKTGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 332 HSP 2 Score: 150.599 bits (379), Expect = 2.378e-37 Identity = 68/119 (57.14%), Postives = 92/119 (77.31%), Query Frame = 2
Query: 1577 TDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPP 1933
TD+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L++ S G + LA LPP
Sbjct: 349 TDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNE---GSSGGGSEQDTLAPLPP 464 HSP 3 Score: 138.658 bits (348), Expect = 2.046e-33 Identity = 65/85 (76.47%), Postives = 73/85 (85.88%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALN-RP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KLS+SP+KVTL D KN LN RP YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE +
Sbjct: 3 ETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESA 87
BLAST of Dvl-2 vs. Ensembl Medaka
Match: dvl1a (dishevelled segment polarity protein 1 [Source:NCBI gene;Acc:101165393]) HSP 1 Score: 211.075 bits (536), Expect = 7.566e-57 Identity = 95/126 (75.40%), Postives = 108/126 (85.71%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VND++FE+MSNDDAVR LRE V K GPI+L VAKCWDP+P+ YFTIPR EPVRPIDP AW+ HT A+T
Sbjct: 252 LNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKTGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTG 377 HSP 2 Score: 151.369 bits (381), Expect = 2.737e-37 Identity = 68/119 (57.14%), Postives = 92/119 (77.31%), Query Frame = 2
Query: 1577 TDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPP 1933
TD+ TI++V+ PDSGL+IRDR+WLKIT+ NA IG+++VDWLY +EGF DR++ARKYA++LLK GY++HTVNK+TFSEQCYY G+ NM+ L+L++ S G + LA LPP
Sbjct: 394 TDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNE---GSSGGGSEQDTLAPLPP 509 HSP 3 Score: 139.428 bits (350), Expect = 2.076e-33 Identity = 65/85 (76.47%), Postives = 73/85 (85.88%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALN-RP--HYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGS 349
ET+IIYHIDEEETPYL+KLS+SP+KVTL D KN LN RP YK+FFKSMD DFGVVKEEI+DD AKLPCF GRV+SWLV AE +
Sbjct: 3 ETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESA 87
BLAST of Dvl-2 vs. Ensembl Medaka
Match: dvl3a (dishevelled segment polarity protein 3 [Source:NCBI gene;Acc:101157324]) HSP 1 Score: 208.379 bits (529), Expect = 2.866e-56 Identity = 95/126 (75.40%), Postives = 107/126 (84.92%), Query Frame = 2
Query: 851 LNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTA 1228
LNI+TV LNM+ FLGISIVGQSN+ GDGGIY+GSIMKGGAVA DGRIEPGDM+L+VNDI+FE+MSNDDAVR LR+ V KPGPI L VAKCWDPNP+ F +PR EP+RPIDP AWV HT AMT
Sbjct: 243 LNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLRDIVHKPGPITLTVAKCWDPNPRSCFALPRSEPIRPIDPAAWVSHTAAMTG 368 HSP 2 Score: 169.088 bits (427), Expect = 3.888e-43 Identity = 82/157 (52.23%), Postives = 115/157 (73.25%), Query Frame = 2
Query: 1466 PMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPP 1936
P GM S + + SSS+PE+ER+ ++ HL+ ++D+ T+ + ++ P+SGL++RDR+WLKIT+ NAFIGS++VDWL+ H+EGFSDR+EARKYA+NLLK G+I+HTVNK+TFSEQCYYV G+ NM+ LSL + S G + L LP P
Sbjct: 372 PYGMSPSMSTVTSTSSSISSSIPETERF-DDFHLSIHSDMATVAKAMACPESGLEVRDRMWLKITIANAFIGSDVVDWLFHHVEGFSDRREARKYASNLLKAGFIRHTVNKITFSEQCYYVFGDLCGNMAHLSLHDHDG-SSGGASDQDTLPPLPHP 526 HSP 3 Score: 138.658 bits (348), Expect = 3.097e-33 Identity = 60/98 (61.22%), Postives = 78/98 (79.59%), Query Frame = 2
Query: 104 ETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNE 397
ET+IIYH+D++ETPYL+KLS+ D+VTL D KN + +P+YK+FFKSMDDDFGVVKEEI+DD AKLPCF GRV+SWLV+ +G + D+ + D E
Sbjct: 3 ETKIIYHLDDQETPYLVKLSVPADRVTLADFKNVIKKPNYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSGDGG----HADTGSVADSLE 96
BLAST of Dvl-2 vs. Planmine SMEST
Match: SMESG000010246.1 (SMESG000010246.1) HSP 1 Score: 1234.94 bits (3194), Expect = 0.000e+0 Identity = 775/775 (100.00%), Postives = 775/775 (100.00%), Query Frame = 2
Query: 65 MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESXXXXXXXXXXXSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLXXXXXXXXXXXXXXYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPXXXXXXXXXXXXXXXQYSVVGPLPCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ 2389
MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPSNNANVATATASSNSQYSVVGPLPCSQPSQHASSNASASAIKKSGSCNSLSGSSSSTSSSSSSNRSNTRINGNASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ
Sbjct: 1 MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNGILDKNESRMLPFQESHFPLINNIKASGGTTTNESDTICDTCTDTDSVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTNTPNGQNPIYETNSSMMSSDLESTSFFDSEDESSRFSTTTCTTMSSRYGRQKQQRRRRRPPAISRASSFSSITDSTMSLNIVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPPSSVNGVHPQVSNLVAPSMQSLLSGGTMLAGTSAATFNAAAFGYMPQPQNINQNTASVSTVGGPPGASVGFFGYPMGMPGQFSQGAGSIVTTSSSLPESERYQEELHLTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLDQVESVSEVGVNGPHHLAALPPPNFSSNKQPISSCINQPPLNINPQLTATSEPLPSNNANVATATASSNSQYSVVGPLPCSQPSQHASSNASASAIKKSGSCNSLSGSSSSTSSSSSSNRSNTRINGNASSVSNMISKNPPPKIPPRTIASVSTNSTNPIISGFQNRGQSSVSQ 775
BLAST of Dvl-2 vs. Planmine SMEST
Match: SMESG000049876.1 (SMESG000049876.1) HSP 1 Score: 208.764 bits (530), Expect = 9.083e-56 Identity = 169/268 (63.06%), Postives = 203/268 (75.75%), Query Frame = 2
Query: 515 SVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTN--------------------TPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSN---KGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPP 1246
S+Y+ +D+V PLR F D+K + ++ N ++ P Q PIYE++SSMMSSDL++TSFFDSED+SSRFS+ T TTMSS+YG+Q++Q RRRR +SRASSFSS+TDST+SLNI+TV LNMDTV FLGISIVGQ+N + GDGGIYVGSIMKGGAVA DGRIEPGDMILEVN ISFE++SN++AVRTLREQVQK GP+ LVVAK WDPNP GY +P+Q+PVRPIDPRAWVLHT AM G PP
Sbjct: 172 SIYN--EDKVPPLRKFSDFKHSVKLKKLRNAQGSHGNSNSSSNNNNSNSNNASNNAPAKQQPIYESSSSMMSSDLDTTSFFDSEDDSSRFSSATETTMSSKYGKQRRQLRRRRKMPHLSRASSFSSMTDSTVSLNIITVTLNMDTVPFLGISIVGQTNGNQENGDGGIYVGSIMKGGAVALDGRIEPGDMILEVNGISFENVSNEEAVRTLREQVQKLGPVTLVVAKSWDPNPTGYM-LPQQDPVRPIDPRAWVLHTQAM--GNMAPP 434 HSP 2 Score: 150.214 bits (378), Expect = 8.091e-37 Identity = 69/105 (65.71%), Postives = 88/105 (83.81%), Query Frame = 2
Query: 101 DETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNG----ILDKNESR 403
+ETRIIY++D+EETPYLIK P+++TLGD KNALNRP+YK+FFKS+DDDFGVVKEEITDD+AKLP GRV+SWLV +EGST SDN S+G ++D ++S+
Sbjct: 2 EETRIIYYVDDEETPYLIKFHSPPEQITLGDFKNALNRPNYKFFFKSLDDDFGVVKEEITDDDAKLPYVNGRVVSWLVVSEGSTQSDNHSSSGKEVLLVDSDKSK 106 HSP 3 Score: 149.443 bits (376), Expect = 1.312e-36 Identity = 68/112 (60.71%), Postives = 90/112 (80.36%), Query Frame = 2
Query: 1565 LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLD-QVESVSEVG 1897
LT N + I+R ++Q DSGL IRDRLWLKIT+ NAFIGS+LVDWLY H++GF+DRK+ARK+A NLLK G+I+HTVNK +FSEQCYYVL + +S ++L+ +++SVS V
Sbjct: 484 LTTNHEPSVIIRAMAQADSGLPIRDRLWLKITIYNAFIGSDLVDWLYSHVQGFTDRKDARKFATNLLKMGFIRHTVNKSSFSEQCYYVLNDMMGALSVMNLESEIDSVSVVA 595
BLAST of Dvl-2 vs. Planmine SMEST
Match: SMESG000049876.1 (SMESG000049876.1) HSP 1 Score: 209.149 bits (531), Expect = 2.083e-55 Identity = 169/268 (63.06%), Postives = 203/268 (75.75%), Query Frame = 2
Query: 515 SVYSAAQDRVGPLRSFHDYKQAGRVAAHANRVNTN--------------------TPNGQNPIYETNXXXXXXXXXXXXXXXXXXXXXXXXXXTCTTMXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXLNIVTVRLNMDTVKFLGISIVGQSN---KGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLREQVQKPGPINLVVAKCWDPNPKGYFTIPRQEPVRPIDPRAWVLHTNAMTAGASEPP 1246
S+Y+ +D+V PLR F D+K + ++ N ++ P Q PIYE++SSMMSSDL++TSFFDSED+SSRFS+ T TTMSS+YG+Q++Q RRRR +SRASSFSS+TDST+SLNI+TV LNMDTV FLGISIVGQ+N + GDGGIYVGSIMKGGAVA DGRIEPGDMILEVN ISFE++SN++AVRTLREQVQK GP+ LVVAK WDPNP GY +P+Q+PVRPIDPRAWVLHT AM G PP
Sbjct: 172 SIYN--EDKVPPLRKFSDFKHSVKLKKLRNAQGSHGNSNSSSNNNNSNSNNASNNAPAKQQPIYESSSSMMSSDLDTTSFFDSEDDSSRFSSATETTMSSKYGKQRRQLRRRRKMPHLSRASSFSSMTDSTVSLNIITVTLNMDTVPFLGISIVGQTNGNQENGDGGIYVGSIMKGGAVALDGRIEPGDMILEVNGISFENVSNEEAVRTLREQVQKLGPVTLVVAKSWDPNPTGYM-LPQQDPVRPIDPRAWVLHTQAM--GNMAPP 434 HSP 2 Score: 150.599 bits (379), Expect = 1.002e-36 Identity = 69/105 (65.71%), Postives = 88/105 (83.81%), Query Frame = 2
Query: 101 DETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRPHYKYFFKSMDDDFGVVKEEITDDEAKLPCFKGRVISWLVTAEGSTVSDNVDSNG----ILDKNESR 403
+ETRIIY++D+EETPYLIK P+++TLGD KNALNRP+YK+FFKS+DDDFGVVKEEITDD+AKLP GRV+SWLV +EGST SDN S+G ++D ++S+
Sbjct: 2 EETRIIYYVDDEETPYLIKFHSPPEQITLGDFKNALNRPNYKFFFKSLDDDFGVVKEEITDDDAKLPYVNGRVVSWLVVSEGSTQSDNHSSSGKEVLLVDSDKSK 106 HSP 3 Score: 149.828 bits (377), Expect = 1.520e-36 Identity = 68/112 (60.71%), Postives = 90/112 (80.36%), Query Frame = 2
Query: 1565 LTKNTDVGTILRVLSQPDSGLDIRDRLWLKITLPNAFIGSNLVDWLYRHIEGFSDRKEARKYAANLLKFGYIKHTVNKVTFSEQCYYVLGNTTLNMSRLSLD-QVESVSEVG 1897
LT N + I+R ++Q DSGL IRDRLWLKIT+ NAFIGS+LVDWLY H++GF+DRK+ARK+A NLLK G+I+HTVNK +FSEQCYYVL + +S ++L+ +++SVS V
Sbjct: 484 LTTNHEPSVIIRAMAQADSGLPIRDRLWLKITIYNAFIGSDLVDWLYSHVQGFTDRKDARKFATNLLKMGFIRHTVNKSSFSEQCYYVLNDMMGALSVMNLESEIDSVSVVA 595
BLAST of Dvl-2 vs. Planmine SMEST
Match: SMESG000056186.1 (SMESG000056186.1) HSP 1 Score: 53.5286 bits (127), Expect = 1.010e-6 Identity = 27/74 (36.49%), Postives = 43/74 (58.11%), Query Frame = 2
Query: 857 IVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLR 1078
+ TV + K LGIS++G+ G G+Y+ ++KGG DGR++PGD ILE+N F + + + A L+
Sbjct: 666 VSTVEITKKPSKGLGISVIGRE---GAKGVYICDVVKGGVADVDGRLKPGDQILEINGEDFRNETQEIAATRLK 736
BLAST of Dvl-2 vs. Planmine SMEST
Match: SMESG000056186.1 (SMESG000056186.1) HSP 1 Score: 53.1434 bits (126), Expect = 1.122e-6 Identity = 27/74 (36.49%), Postives = 43/74 (58.11%), Query Frame = 2
Query: 857 IVTVRLNMDTVKFLGISIVGQSNKGGDGGIYVGSIMKGGAVAQDGRIEPGDMILEVNDISFEDMSNDDAVRTLR 1078
+ TV + K LGIS++G+ G G+Y+ ++KGG DGR++PGD ILE+N F + + + A L+
Sbjct: 465 VSTVEITKKPSKGLGISVIGRE---GAKGVYICDVVKGGVADVDGRLKPGDQILEINGEDFRNETQEIAATRLK 535 The following BLAST results are available for this feature:
BLAST of Dvl-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dvl-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dvl-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Dvl-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Dvl-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dvl-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033103 ID=SMED30033103|Name=Dvl-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3159bpback to top protein sequence of SMED30033103-orf-1 >SMED30033103-orf-1 ID=SMED30033103-orf-1|Name=SMED30033103-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=776bp MTNCATSGNVISDETRIIYHIDEEETPYLIKLSISPDKVTLGDLKNALNRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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