Innexin

Overview
NameInnexin
Smed IDSMED30033065
Length (bp)1728
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30033065) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30033065) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30033065) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30033065) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033065

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
central nervous systemSMED30033065SMESG000046667.1 dd_Smed_v4_11077_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30033065SMESG000046667.1 SmedASXL_013997SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30033065SMESG000046667.1 SmedASXL_013996SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30033065SMESG000046667.1 dd_Smed_v4_11077_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033065SMESG000046667.1 dd_Smed_v4_11077_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30033065SMESG000046667.1 dd_Smed_v4_11077_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30033065SMESG000046667.1 OX_Smed_1.0.09661ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 334.724 bits (857), Expect = 4.660e-110
Identity = 159/379 (41.95%), Postives = 243/379 (64.12%), Query Frame = 2 
Query:  266 RFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 1402
            +F  DDD  D+LN+ +T+ ++ +F +++SA+QY+G PI CWVP  F+   E+Y E+ CWV +TYF+ P    IP N  +RE+R++ YYQWVPF+L  +A LF +P I+WRL +WQSGI++ S++Q+ACD  ++ D E R   +  +A ++++ L+ +H   +    ++ N I       C++  G+ +  LYI  K+LY +N++ Q F++N  LG    +YG  ++  L +GR W ESGHFPR+T+CDFE++ L N HR+TVQCVL INMFNEKIF+FLWFW+ L++  T+ S     Y   +   ++NFV K+L   +  + +     R FV   LR DGVFLLR++A +AG+L   E+  +LW  Y D+K     D+
Sbjct:   16 QFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFL-PLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLL-DLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLII------CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV 386
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 321.627 bits (823), Expect = 2.252e-104
Identity = 159/382 (41.62%), Postives = 242/382 (63.35%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWR-LFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVL---VSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRS 1411
            DDDF D+LN+ +TS ++  F +I+SA+QY+G PI CWVP +F+ A E+Y E+ CWV +TY++ P   + P    DR  R++ YYQWVPF+L  +A  F IPCI+WR L +W SGIN+ S+ Q+ACD  ++ D + R   V  +A H++  L  +    +  G           C+   K + +Y+  LY+  KMLY+ NV+ Q F++N  LGT+  FYGF +++ L +GR W  SG+FPR+TMCDFE+R L N H +TVQCVL INMFNEKIF+FLWFW+ +   VSAV++  +I +++  G     + F+ K+  LR       +   + FV K L +DGVF +R+++ +AGD++A+E+  +LW  ++D   ++  ++F  
Sbjct:   18 DDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYL-PLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMM-DADARAATVQTIAGHMEDALEIQREVTDVSG----------MCV--QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPG---QHMKFIRKY--LRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKSPIEMFEG 380
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 317.775 bits (813), Expect = 1.407e-103
Identity = 158/370 (42.70%), Postives = 237/370 (64.05%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWR-LFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVL---VSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSD 1375
            DDDF D+LN+ +TS ++  F +I+SA+QY+G PI CWVP +F+ A E+Y E+ CWV +TY++ P   + P    DR  R++ YYQWVPF+L  +A  F IPCI+WR L +W SGIN+ S+ Q+ACD  ++ D + R   V  +A H++  L  +    +  G           C+   K + +Y+  LY+  KMLY+ NV+ Q F++N  LGT+  FYGF +++ L +GR W  SG+FPR+TMCDFE+R L N H +TVQCVL INMFNEKIF+FLWFW+ +   VSAV++  +I +++  G     + F+ K+  LR       +   + FV K L +DGVF +R+++ +AGD++A+E+  +LW  ++D
Sbjct:   18 DDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYL-PLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMM-DADARAATVQTIAGHMEDALEIQREVTDVSG----------MCV--QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPG---QHMKFIRKY--LRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFND 368
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 317.775 bits (813), Expect = 1.407e-103
Identity = 158/370 (42.70%), Postives = 237/370 (64.05%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWR-LFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVL---VSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSD 1375
            DDDF D+LN+ +TS ++  F +I+SA+QY+G PI CWVP +F+ A E+Y E+ CWV +TY++ P   + P    DR  R++ YYQWVPF+L  +A  F IPCI+WR L +W SGIN+ S+ Q+ACD  ++ D + R   V  +A H++  L  +    +  G           C+   K + +Y+  LY+  KMLY+ NV+ Q F++N  LGT+  FYGF +++ L +GR W  SG+FPR+TMCDFE+R L N H +TVQCVL INMFNEKIF+FLWFW+ +   VSAV++  +I +++  G     + F+ K+  LR       +   + FV K L +DGVF +R+++ +AGD++A+E+  +LW  ++D
Sbjct:   18 DDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYL-PLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMM-DADARAATVQTIAGHMEDALEIQREVTDVSG----------MCV--QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPG---QHMKFIRKY--LRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFND 368
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 311.612 bits (797), Expect = 7.496e-101
Identity = 161/370 (43.51%), Postives = 235/370 (63.51%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWR-LFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLK-LRQKPETITKNKC--RNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSD 1375
            DDDF D+LN+ +T+ +L  F L++SA+QY+G PI CWVP  F+ A E+Y E+ CWV +TY+V P    IP+ I  R +R++ YYQWVPFIL  +A LF +PCI+WR L  W SGINL  ++Q+ACD  ++ D E +   V  +A H+   +   +++R   G     F   +    C +  G Y+  LYI  K+LY  NV+ QFF++N +LG+N   YGF L+K L     W ++G FPR+T+CDFE+R L N HR+TVQCVL INMFNEKIF+FLWFWF+    VTV + +     + +    ++FV K+L+ L   P     +    R F    LR DGVF+LR+++ +AG+L++SE+  +LW+ +++
Sbjct:   18 DDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWV-PMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLM-DSEIKTRTVYTMARHMQDEVQLTNIDRQ--GHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 383
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 127.102 bits (318), Expect = 7.586e-32
Identity = 112/384 (29.17%), Postives = 180/384 (46.88%), Query Frame = 2 
Query:  296 RLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTY-------------FVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQL---ADGRMWHESGHFPRITMCDF-EIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWR-LYSDHKSETK 1393
            R+++  T  +L+ F+L++++RQYIG PI C V        + Y    CW+ ST+              V+PGV S  +  D+ +  K  YYQWV F+L  QA LF +P  +W+  +W+ G   + VM +  +  I+ D EC+      +  +    LN RH           NF A +                + +C+ L  +NVI Q + ++  L   ++ YG D++K      D R+   +  FP++T C F +     +   +   CVLP+N+ NEKI++FLWFWF+++S   + S ISL Y+I +V        + L LR +   + +++    V         FLL  L +N   LI  E+   L R +  D  S  K
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--YYQWVCFVLFFQAILFYVPRYLWK--SWEGGRLKMLVMDL--NSPIVND-ECKNDRKKILVDYFIGNLN-RH-----------NFYAFR----------------FFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILS---IMSGISLIYRIAVVAGP---KLRHLLLRAR-SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDLSREMSGDEHSAHK 362
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 127.102 bits (318), Expect = 7.586e-32
Identity = 112/384 (29.17%), Postives = 180/384 (46.88%), Query Frame = 2 
Query:  296 RLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTY-------------FVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQL---ADGRMWHESGHFPRITMCDF-EIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWR-LYSDHKSETK 1393
            R+++  T  +L+ F+L++++RQYIG PI C V        + Y    CW+ ST+              V+PGV S  +  D+ +  K  YYQWV F+L  QA LF +P  +W+  +W+ G   + VM +  +  I+ D EC+      +  +    LN RH           NF A +                + +C+ L  +NVI Q + ++  L   ++ YG D++K      D R+   +  FP++T C F +     +   +   CVLP+N+ NEKI++FLWFWF+++S   + S ISL Y+I +V        + L LR +   + +++    V         FLL  L +N   LI  E+   L R +  D  S  K
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--YYQWVCFVLFFQAILFYVPRYLWK--SWEGGRLKMLVMDL--NSPIVND-ECKNDRKKILVDYFIGNLN-RH-----------NFYAFR----------------FFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILS---IMSGISLIYRIAVVAGP---KLRHLLLRAR-SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDLSREMSGDEHSAHK 362
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 127.102 bits (318), Expect = 7.586e-32
Identity = 112/384 (29.17%), Postives = 180/384 (46.88%), Query Frame = 2 
Query:  296 RLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTY-------------FVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQL---ADGRMWHESGHFPRITMCDF-EIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWR-LYSDHKSETK 1393
            R+++  T  +L+ F+L++++RQYIG PI C V        + Y    CW+ ST+              V+PGV S  +  D+ +  K  YYQWV F+L  QA LF +P  +W+  +W+ G   + VM +  +  I+ D EC+      +  +    LN RH           NF A +                + +C+ L  +NVI Q + ++  L   ++ YG D++K      D R+   +  FP++T C F +     +   +   CVLP+N+ NEKI++FLWFWF+++S   + S ISL Y+I +V        + L LR +   + +++    V         FLL  L +N   LI  E+   L R +  D  S  K
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--YYQWVCFVLFFQAILFYVPRYLWK--SWEGGRLKMLVMDL--NSPIVND-ECKNDRKKILVDYFIGNLN-RH-----------NFYAFR----------------FFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILS---IMSGISLIYRIAVVAGP---KLRHLLLRAR-SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDLSREMSGDEHSAHK 362
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 127.102 bits (318), Expect = 7.586e-32
Identity = 112/384 (29.17%), Postives = 180/384 (46.88%), Query Frame = 2 
Query:  296 RLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTY-------------FVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQL---ADGRMWHESGHFPRITMCDF-EIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWR-LYSDHKSETK 1393
            R+++  T  +L+ F+L++++RQYIG PI C V        + Y    CW+ ST+              V+PGV S  +  D+ +  K  YYQWV F+L  QA LF +P  +W+  +W+ G   + VM +  +  I+ D EC+      +  +    LN RH           NF A +                + +C+ L  +NVI Q + ++  L   ++ YG D++K      D R+   +  FP++T C F +     +   +   CVLP+N+ NEKI++FLWFWF+++S   + S ISL Y+I +V        + L LR +   + +++    V         FLL  L +N   LI  E+   L R +  D  S  K
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--YYQWVCFVLFFQAILFYVPRYLWK--SWEGGRLKMLVMDL--NSPIVND-ECKNDRKKILVDYFIGNLN-RH-----------NFYAFR----------------FFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILS---IMSGISLIYRIAVVAGP---KLRHLLLRAR-SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDLSREMSGDEHSAHK 362
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 116.701 bits (291), Expect = 4.316e-28
Identity = 98/379 (25.86%), Postives = 172/379 (45.38%), Query Frame = 2 
Query:  272 MRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVE-------------PGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLA---DGRMWHESGHFPRITMCD-FEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSL 1357
            ++ D    RL+++ T  +L+ F+LII+ RQY+G PI C          E+   + CW+ STY ++             PG+ +   +  D++  K  YYQWV F L  QA LF  P  +W+  +W+ G     +M +  D+ I  + E ++     + +                             LW +  Y ++    Y +C++L ++NVI Q F+MNR     +  +G  ++  +    + RM      FPR+T C  F+        ++   C+LP+N+ NEKI+IFLWFW      +T  + ++L Y++ ++++    V  F   R +   + ++     V +    D  FLL LL +N   +I  ++   L
Sbjct:   17 VKTDSIVFRLHYSITVMILMSFSLIITTRQYVGNPIDC---VHTKDIPEDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYK--YYQWVCFCLFFQAILFYTPRWLWK--SWEGGKIHALIMDL--DIGICSEAEKKQKKKLLLDY-----------------------------LWENLRYHNWWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFW---FILLTFLTLLTLIYRVVIIFSPRMRVYLF---RMRFRLVRRDAIEIIVRRSKMGDW-FLLYLLGENIDTVIFRDVVQDL 350
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 334.724 bits (857), Expect = 5.927e-109
Identity = 159/379 (41.95%), Postives = 243/379 (64.12%), Query Frame = 2 
Query:  266 RFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 1402
            +F  DDD  D+LN+ +T+ ++ +F +++SA+QY+G PI CWVP  F+   E+Y E+ CWV +TYF+ P    IP N  +RE+R++ YYQWVPF+L  +A LF +P I+WRL +WQSGI++ S++Q+ACD  ++ D E R   +  +A ++++ L+ +H   +    ++ N I       C++  G+ +  LYI  K+LY +N++ Q F++N  LG    +YG  ++  L +GR W ESGHFPR+T+CDFE++ L N HR+TVQCVL INMFNEKIF+FLWFW+ L++  T+ S     Y   +   ++NFV K+L   +  + +     R FV   LR DGVFLLR++A +AG+L   E+  +LW  Y D+K     D+
Sbjct:   16 QFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFL-PLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLL-DLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLII------CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV 386
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 4.333e-99
Identity = 161/370 (43.51%), Postives = 235/370 (63.51%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWR-LFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLK-LRQKPETITKNKC--RNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSD 1375
            DDDF D+LN+ +T+ +L  F L++SA+QY+G PI CWVP  F+ A E+Y E+ CWV +TY+V P    IP+ I  R +R++ YYQWVPFIL  +A LF +PCI+WR L  W SGINL  ++Q+ACD  ++ D E +   V  +A H+   +   +++R   G     F   +    C +  G Y+  LYI  K+LY  NV+ QFF++N +LG+N   YGF L+K L     W ++G FPR+T+CDFE+R L N HR+TVQCVL INMFNEKIF+FLWFWF+    VTV + +     + +    ++FV K+L+ L   P     +    R F    LR DGVF+LR+++ +AG+L++SE+  +LW+ +++
Sbjct:  138 DDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWV-PMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLM-DSEIKTRTVYTMARHMQDEVQLTNIDRQ--GHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 503
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 283.108 bits (723), Expect = 2.543e-88
Identity = 146/426 (34.27%), Postives = 245/426 (57.51%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVL-GTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPE--------------------TITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDH--KSETKTDLFRSKENHRNLASGQQILTHKPQLNESLL 1486
            DDD  DRLN+ +T  +L +  L+ISA+QY G PI CWV      + EEY ES CW+ +TY++ P   ++P +   RE++++ YYQWVPFIL+ +A +F++PCI WRL ++QSG+N+ +++  ACD + + D   R+  V  +  +    L+ +  N      R R +IA     +   + G  +  +Y   K+LY +NV++QFFI+N  L  + + F+GF ++  +  GR W E+GHFPR+T+CDFE+R LAN +RYTVQC L IN+ NEK+F FLW W+++++ +T  SFI       +   ++++V KF+++ +  E                        +   +FV   L+ DG+ +LR+++ +AGD+I  ++  +LW+ Y +   +   + +  +  E  R   + ++I+   P   +S L
Sbjct:   20 DDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWI-PMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRI---RARGWIAR--IKFSRFLSGQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRERNWREFEEHEEMKDVEMRRIQGTRERIVIANPGQTKSFL 439
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2)

HSP 1 Score: 281.952 bits (720), Expect = 1.203e-87
Identity = 147/425 (34.59%), Postives = 243/425 (57.18%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVL-GTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPE--------------------TITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKE-NHRNLASGQQILTHKPQLNESLL 1486
            DDD  DRLN+ +T  +L +  L+ISA+QY G PI CWV      + EEY ES CW+ +TY++ P   ++P +   RE++++ YYQWVPFIL+ +A +F++PCI WRL ++QSG+N+ +++  ACD + + D   R+  V  +  +    L+ +  N      R R +IA     +   + G  L  L+   K+LY +NV++QF I+N  L  +++ F+GF ++  +  GR W E+GHFPR+T+CDFE+R LAN +RYTVQC L IN+ NEK+F FLW W+++++ +T  SFI       +   ++++V KF+++ +  E                        +    FV   L+ DGV +LR+++ +AGD+I  ++  +LW+ + +       +    K+   R +  G++I+   P   +S L
Sbjct:   36 DDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWI-PMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRI---RARGWIAR--IKFSRFLSGQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRERNWREFEEHEEMKDVEMRRIHGGERIVISNPGQTKSFL 454
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 267.314 bits (682), Expect = 2.033e-82
Identity = 149/425 (35.06%), Postives = 223/425 (52.47%), Query Frame = 2 
Query:  281 DDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLP 1555
            DD  DRL++  T+ LL  F++++S +QY+G  I CW+P EF    E+YAE  C++ +T+F+ P    IP +++DR+  ++ YYQWVP +L  QAF+F +P  IW     Q G++  SV+  A  +   +D E R   V+ +   I   L+TR  N     GR         C    K  GS    LYI  K++Y+ NV  QF I+N+ LG     +GF     L  GR W +SG FPR+T+CDF +RKLAN HRYTVQCVL INMFNEKI++F+WFWFV V   T  + +   Y++    +R N++   L          K    +F    L+ DGV L+R +  +AG ++  EI + L++ + +           + +++R+   G    +  P L E           H  +  P+K +   P
Sbjct:   21 DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFI-PERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRS-QDSETRTKGVNKLVDFIGDILDTRSKNEY---GRFY-------CYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGE-----------NLQHNRDFHHGHSTKSTSPGLEE---------GHHEHLYTPEKMKLMAP 413
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A158R819 (Innexin OS=Taenia asiatica OX=60517 GN=inx PE=3 SV=1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 263/458 (57.42%), Postives = 335/458 (73.14%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKE-NHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPT 1585
            M++  FAGL+KFK  AG+  RDDDFADR +H FT+ LLVIFTL++SARQYIGKPIACWVPTEF+RAQEEYAESVCWVTSTYF+     ++P++  +RE+RK+LYYQWVPF+LM QAFLFN+PCIIWRLFNWQSGI+L S+M+V+CD+E+I+D + RK N++YVA HI+  L ++   R+  G   R  +A  CC W  K YG+YLICLY+I K LYI NV+ QFF+MNR+LGTNYTFYG DL++ +A+G +W ESG+FPRIT+CDFEIRKLAN HRYTVQCVLPINMFNEKIFIFLWFWF+LVSAV++SSF+  +YK     NRI+F+ KFLKLR   E   K +   FV+ +LR DGVF+LRL+AQNAG+L+ASEI + LW+++   +S   T+  R+ E   ++  SG   +   P        L   S +   I  P     K P        P+
Sbjct:    1 MDTHFFAGLTKFKLDAGKHRRDDDFADRFSHNFTTLLLVIFTLVVSARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFLPTKQKTVPESTQEREERKILYYQWVPFVLMIQAFLFNLPCIIWRLFNWQSGIHLSSIMEVSCDIEMIRDPDSRKSNITYVARHIEDALTSQREYRDGCGVNCRQAMARSCCFWFGKRYGNYLICLYLITKALYIFNVVGQFFLMNRILGTNYTFYGLDLIRDIAEGYLWEESGNFPRITLCDFEIRKLANSHRYTVQCVLPINMFNEKIFIFLWFWFILVSAVSISSFLYWSYKSSFRSNRIHFIRKFLKLRDSLEPGEKKRSYAFVDSYLRQDGVFILRLVAQNAGELVASEIVEKLWQMFKRRQSLPTTEKVRANEVGWKSGVSGHSHIHSPPMRAPRSSELSPTSVTSPTINAPTVHGSKHPFGSGLPPPPS 458
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4E0RPY2 (Innexin OS=Fasciola hepatica OX=6192 GN=inx PE=3 SV=1)

HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0
Identity = 258/389 (66.32%), Postives = 315/389 (80.98%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHK 1381
            M++  FAGL+KFK  AG+F RDDDF+DR +HTFT+ LLVIFTL+ISARQYIGKPIACWVPTEF+RAQEEYAESVCWVTSTYF+     S+P  I DREDRK+ YYQWVPFILM QAFLFN+PCI+WRLFNWQSGI+L S+M+VAC++E+IKD E RK NV+YVA H++  L  +   R+    R R+ +A+ CCLW  K YG+YLICLY+I K LYILNV+ QFF MNR+LGTNYTFYG DL++ LA+G MW ESG+FPRIT+CDFE+RKLAN HR+TVQCVLPINMFNEKIFIFLWFWF+LV+AV +SSF+  +YK     NR++F+ KFLKLR   E   K +   FV+ +LR DGVF+LRL+AQNAG+L+ASEI + LW +Y  H+
Sbjct:    1 MDTHFFAGLTKFKLDAGKFRRDDDFSDRFSHTFTTLLLVIFTLVISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFIPTNDVSVPVKIADREDRKIHYYQWVPFILMLQAFLFNLPCIVWRLFNWQSGIHLSSIMEVACEIEMIKDPETRKSNVTYVARHVEDALTAQREYRSGCAVRCRHCLAKSCCLWFGKRYGNYLICLYLITKSLYILNVVGQFFFMNRILGTNYTFYGLDLLRDLAEGYMWQESGNFPRITLCDFEVRKLANTHRHTVQCVLPINMFNEKIFIFLWFWFILVAAVNISSFLYWSYKSSFHGNRVHFIRKFLKLRDALEPGDKKRTFAFVDSYLRQDGVFILRLVAQNAGELVASEIVERLWNMYKSHQ 389
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LLY4 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 256/390 (65.64%), Postives = 314/390 (80.51%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKS 1384
            M++  FAGL+KFK  AG+F RDDDF+DR +HTFT  LLVIFTL+ISARQYIGKPIACWVPTEF+RAQEEYAESVCWVTSTYF+     ++P N+ DREDRK+ YYQWVPFILM QAFLFN+PCI+WRLFNWQSGI+L S+M+VAC++E+IKD E RK NV+YVA HI+  L T+   R+  G + R+F+A  CCLW  K YG+YLICLY+I K LYILNV+ QFF MNR+LGTNYTFYG DL++ +A+G +W ESG+FPRIT+CDFE+RKLAN HR+TVQCVLPINMFNEKIFIFLWFWF+LV+AV  SSF+  +YK     NR++F+ KFLKLR   E   K +   FV+ +LR DGVF+LRL+  NAG+L+ASEI + LW LY   ++
Sbjct:    1 MDTHFFAGLTKFKLDAGKFRRDDDFSDRFSHTFTPLLLVIFTLVISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFIPTREVNVPVNLADREDRKIHYYQWVPFILMIQAFLFNLPCIVWRLFNWQSGIHLSSIMEVACEIEMIKDPETRKSNVTYVARHIEDALTTQREYRSGCGVKCRHFLARSCCLWFGKRYGNYLICLYLITKSLYILNVVGQFFFMNRILGTNYTFYGIDLLRDIAEGIVWQESGNFPRITLCDFEVRKLANVHRHTVQCVLPINMFNEKIFIFLWFWFILVAAVNTSSFLYWSYKSSFQGNRVHFIRKFLKLRDALEPGDKKRTAAFVDSYLRQDGVFILRLVGLNAGELVASEIVERLWSLYKSRQT 390
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A075A080 (Innexin OS=Opisthorchis viverrini OX=6198 GN=inx PE=3 SV=1)

HSP 1 Score: 558.14 bits (1437), Expect = 0.000e+0
Identity = 256/390 (65.64%), Postives = 314/390 (80.51%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKS 1384
            M++  FAGL+KFK  AG+F RDDDF+DR +HTFT  LLVIFTL+ISARQYIGKPIACWVPTEF+RAQEEYAESVCWVTSTYF+     ++P N+ DREDRK+ YYQWVPFILM QAFLFN+PCI+WRLFNWQSGI+L S+M+VAC++E+IKD E RK NV+YVA HI+  L T+   R+  G + R+F+A  CCLW  K YG+YLICLY+I K LYILNV+ QFF MNR+LGTNYTFYG DL++ +A+G +W ESG+FPRIT+CDFE+RKLAN HR+TVQCVLPINMFNEKIFIFLWFWF+LV+AV  SSF+  +YK     NR++F+ KFLKLR   E   K +   FV+ +LR DGVF+LRL+  NAG+L+ASEI + LW LY   ++
Sbjct:    1 MDTHFFAGLTKFKLDAGKFRRDDDFSDRFSHTFTPLLLVIFTLVISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFIPTREVNVPVNLADREDRKIHYYQWVPFILMIQAFLFNLPCIVWRLFNWQSGIHLSSIMEVACEIEMIKDPETRKSNVTYVARHIEDALTTQREYRSGCGVKCRHFLARSCCLWFGKRYGNYLICLYLITKSLYILNVVGQFFFMNRILGTNYTFYGIDLLRDIAEGIVWQESGNFPRITLCDFEVRKLANVHRHTVQCVLPINMFNEKIFIFLWFWFILVAAVNTSSFLYWSYKSSFQGNRVHFIRKFLKLRDALEPGDKKRTAAFVDSYLRQDGVFILRLVGLNAGELVASEIVERLWSLYKSRQT 390
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A5K4F1T1 (Innexin OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 541.576 bits (1394), Expect = 0.000e+0
Identity = 255/398 (64.07%), Postives = 320/398 (80.40%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFR 1408
            M++  FAGL+KFK  AG+  RDDDF+DR +HTFTS LL+IFTLIISARQYIGKPIACWVPTEF+RAQEEYAESVCWVTSTYF+     +IP+NI +RE+RK+ YYQWVPFILM QAFLFN+PC+IWRLFNWQSGI+L S+M+VAC++E+IKD E RK N++YVA HI+  L+++   R+  G R ++ +A+ CCLW  K YG+YLICLY+I K LYI NV+ QFF+MN++LGTNYTFYG DL++ +++G +W ESG+FPRIT+CDFE+RK+ANKHR+TVQCVLPINMFNEKIFIFLWFWF+LV+AV  SSF+  +YK      RI F+ KFLKLR   E   K K   FV+ +LR DGVF+LRL AQNAG+L+ASEI + LW +Y  H++ + T   R
Sbjct:    1 MDTHFFAGLTKFKLDAGKLRRDDDFSDRFSHTFTSLLLIIFTLIISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFIPTQDINIPENISERENRKIHYYQWVPFILMIQAFLFNLPCLIWRLFNWQSGIHLSSIMEVACEIEMIKDPETRKSNITYVARHIEDALSSQREYRSGCGVRFKHCLAKSCCLWFGKRYGNYLICLYLITKSLYIFNVVGQFFLMNKILGTNYTFYGLDLLRDISEGYVWQESGNFPRITLCDFEVRKVANKHRHTVQCVLPINMFNEKIFIFLWFWFILVAAVNTSSFLYWSYKSSFRGTRIQFIRKFLKLRGALEPGDKKKTLTFVDSYLRQDGVFILRLTAQNAGELVASEIIERLWNMYRAHQNVSTTSTSR 398
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 1004.59 bits (2596), Expect = 0.000e+0
Identity = 480/480 (100.00%), Postives = 480/480 (100.00%), Query Frame = 2 
Query:  173 MVRSRNFDQFASLNMESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 1612
            MVRSRNFDQFASLNMESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV
Sbjct:    1 MVRSRNFDQFASLNMESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 480
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 975.311 bits (2520), Expect = 0.000e+0
Identity = 466/466 (100.00%), Postives = 466/466 (100.00%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 1612
            MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV
Sbjct:    1 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 466
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000035987.1 (SMESG000035987.1)

HSP 1 Score: 493.041 bits (1268), Expect = 1.603e-170
Identity = 254/489 (51.94%), Postives = 328/489 (67.08%), Query Frame = 2 
Query:  215 MESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQK-PETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLW-------RLYSDHKSE----TKTDLFRSKENHRNLASGQQI--------LTHKPQLNE---SLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 1612
            ME+  F+GLSKFK   G+F RDDD +DR NH FT+ LLV F+L++S RQY+GKPIACWVPTEF+ +QEEYAES+CWV+STYF+ P   SIP+N   RE++K+LYYQWVPFILM QA LFN PC +WRL NWQSG+N+ +++ +A D E+IKD E RK N+ ++  HID  L  +   RN    + R+ +A+  C+W  + YG+YL+C+Y ICK LYILNVI QFF+MNR LGTNYTFYG DL+ QL+ G  W ESG+FPR+TMCDF IRKLAN+HRYTVQCVLPIN+FNEKIFIFLWFWFV ++ +TV SFI  T K      R NF+ KFL L+    E   + K   F++  L+ DGVF+LRLLA N GDLIA+EIT+ LW       R+ S  +S+       D++     +R+  S   I        +   P L E   S  +    SS+ + I  P++   K+     A  +  +EEDPGEFV
Sbjct:    1 MEAPFFSGLSKFKNDVGKFRRDDDQSDRFNHFFTTILLVCFSLVVSTRQYVGKPIACWVPTEFTSSQEEYAESICWVSSTYFINPYQGSIPENTQQREEKKILYYQWVPFILMLQAILFNFPCCVWRLLNWQSGLNISAIIDIAGDTEMIKDYEQRKANLDFITRHIDDTLRIQREYRNGCTVQCRHCLAQHFCMWFGRRYGNYLVCVYTICKSLYILNVIGQFFLMNRFLGTNYTFYGLDLIYQLSIGNEWTESGNFPRVTMCDFNIRKLANQHRYTVQCVLPINLFNEKIFIFLWFWFVFIAIITVHSFIHWTSKSVCRIQRYNFIRKFLVLKDALQEAGDRKKLYAFIDLFLQQDGVFILRLLALNCGDLIAAEITEYLWCRFKECARMDSGERSKLFYLDSGDVYSKARPYRSRKSKDLIEPVQSRRRIPSAPALKENSHSQSNSNTSSSNRSNISAPNRPPKKMSC---ANLHHVSEEDPGEFV 486
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000037115.1 (SMESG000037115.1)

HSP 1 Score: 361.688 bits (927), Expect = 7.309e-120
Identity = 183/432 (42.36%), Postives = 264/432 (61.11%), Query Frame = 2 
Query:  341 LIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNT-VGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLY------SDHKSET-KTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKIRGPDKSRHKLPLNEFATANPTAEEDPGEFV 1612
            +IISARQYIGKPI+CWVP EF+R+QEEY ESVCWVTSTYF+     +I  + + R   KL YYQWVPFIL+ QA LF IPC++WR+FNWQSG  +  + +++  ++I  + + R  N+  +A H++    TR   + T +  +++  I    C W  K +G++L+ LY+  K LY LN+  Q  +MN  LGTNYT YG  L+  ++ GR W ESG+FPR+T+CDF I KLAN H+YTVQCVLPINMFNEKI+IFLWFW VLVS  TV SF++   K+ ++  ++ F+  +L+ R           + FV +HLR DGVF+L ++   AG+++  E+ + +W++Y      S  K ET +  L   KE  ++L        +K Q+    LS   ++ S    +     +     N   ++N   EE+ G+FV
Sbjct:    1 MIISARQYIGKPISCWVPAEFTRSQEEYTESVCWVTSTYFLPNS--TISNDNERRNVTKLTYYQWVPFILIAQAALFYIPCLVWRMFNWQSGYQVTRISELSRHLQICINSQDRHYNIVLLALHLNDIFKTRLTVQGTGIATKIKKCICSVFCFWFGKRFGNFLVGLYLFVKFLYSLNIFGQLILMNTYLGTNYTLYGIHLLLDISSGRSWQESGNFPRVTICDFTIHKLANTHKYTVQCVLPINMFNEKIYIFLWFWMVLVSIKTVQSFVTWGLKLTMLDYKVGFIQHYLRYRNIITCHELEDVKYFVTQHLRSDGVFVLHIVKSIAGEIVCGELMEEIWKIYIQPHRHSKVKRETDERQLLTEKERDKHLIPLIHSRLNKSQIRFGFLSNSLNAKSDVSYKNHFNFKSLTKPNLIQSSNNDEEEEGGDFV 430
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000060499.1 (SMESG000060499.1)

HSP 1 Score: 322.398 bits (825), Expect = 8.091e-104
Identity = 162/385 (42.08%), Postives = 235/385 (61.04%), Query Frame = 2 
Query:  278 DDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCL-------NTRHVNRNTVGGR--MRNFIAEKCCLWC-SKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 1402
            DDDF DRLN+ FT  LL +F  +I  RQY+GKPI CW+P EF+R  EEY E+ CWV++TYF    + +   + D R+++ + YYQW P +L  Q+ LF IPC+IWR  + QSG N+  ++QVA D       E  + ++S++A H+D CL         +H  R T G R  +   +A+  C+ C  K+ G++L  LYI  K+LY++N+I Q ++M + +GT Y FYG  ++  L  G  WH SG+FPR+T CD E +KL   H Y++QCVLP+NMF EKI+IFLWFW V+V   T+ S  S   +IG   NRI  +  +L+L        K   R F E +LR DG FL++L+A N GDL+A ++   +W++Y   + +   +L
Sbjct:   61 DDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFAS--IQNRMPSKDARKEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYRHRICYEHKHFMR-TNGKRSTISRCLAKLRCICCLGKLQGNFLTVLYISIKILYLINIIGQLYLMEKFIGTKYAFYGIRVLWDLMRGHEWHYSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLFSLFSWIKRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEEL 442
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-94.660e-11041.95Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
inx-12.252e-10441.62Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.407e-10342.70Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.407e-10342.70Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
unc-77.496e-10143.51Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx27.586e-3229.17gene:FBgn0027108 transcript:FBtr0301860[more]
Inx27.586e-3229.17gene:FBgn0027108 transcript:FBtr0071005[more]
Inx27.586e-3229.17gene:FBgn0027108 transcript:FBtr0332314[more]
Inx27.586e-3229.17gene:FBgn0027108 transcript:FBtr0071006[more]
shakB4.316e-2825.86gene:FBgn0085387 transcript:FBtr0112571[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL5.927e-10941.95Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL4.333e-9943.51Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|A8WVX4|INX19_CAEBR2.543e-8834.27Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
sp|O61715|INX19_CAEEL1.203e-8734.59Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q19746|INX3_CAEEL2.033e-8235.06Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A158R8190.000e+057.42Innexin OS=Taenia asiatica OX=60517 GN=inx PE=3 SV... [more]
A0A4E0RPY20.000e+066.32Innexin OS=Fasciola hepatica OX=6192 GN=inx PE=3 S... [more]
A0A4S2LLY40.000e+065.64Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
A0A075A0800.000e+065.64Innexin OS=Opisthorchis viverrini OX=6198 GN=inx P... [more]
A0A5K4F1T10.000e+064.07Innexin OS=Schistosoma mansoni OX=6183 PE=4 SV=1[more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000046667.10.000e+0100.00SMESG000046667.1[more]
SMESG000046667.10.000e+0100.00SMESG000046667.1[more]
SMESG000035987.11.603e-17051.94SMESG000035987.1[more]
SMESG000037115.17.309e-12042.36SMESG000037115.1[more]
SMESG000060499.18.091e-10442.08SMESG000060499.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033065 ID=SMED30033065|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1728bp
TTTATAAAATACCAATTTCTATTAATTTCTAACAGGAAGTTGATTAATTT
TTTATTTACCGAATTTCTATCGATCTTTGGACTAAAGGAAATTTATTTAA
TCGTGAATTATACATTTAACTATAGAAACATCGTGATGACAACAAATTTC
CAGTGGATCACTGGTTTATAAAATGGTCCGTTCGAGAAACTTTGATCAAT
TCGCTAGTTTGAATATGGAATCTCAATTATTTGCCGGATTAAGTAAATTT
AAATGGTACGCTGGTCGGTTTATGAGAGATGACGATTTTGCTGATCGGCT
CAATCATACATTCACTTCTTTTCTTCTCGTAATTTTCACCTTGATCATTT
CCGCTCGACAGTACATTGGGAAACCAATAGCTTGTTGGGTACCGACGGAA
TTCTCTCGCGCTCAAGAAGAATATGCCGAATCTGTTTGTTGGGTAACGAG
CACTTACTTTGTTGAACCCGGAGTTCACTCAATTCCACAAAATATCGACG
ATAGAGAAGACAGAAAATTACTTTATTATCAATGGGTGCCATTTATACTA
ATGGGGCAAGCTTTTTTATTCAATATTCCTTGCATTATTTGGCGTCTCTT
CAACTGGCAATCAGGTATTAATCTTGTCAGTGTGATGCAAGTAGCCTGCG
ATGTTGAAATAATCAAAGACAGAGAATGTCGGAAAGTTAATGTATCATAT
GTAGCTCATCATATAGATCAGTGTTTAAATACCCGCCATGTCAATCGCAA
CACAGTCGGTGGAAGGATGCGAAACTTTATTGCAGAAAAATGCTGCCTTT
GGTGCAGCAAAATGTATGGTAGTTATCTCATCTGTCTCTATATAATTTGC
AAGATGCTCTACATTTTGAACGTAATCAGTCAGTTCTTCATAATGAATCG
TGTTCTTGGCACAAATTACACTTTCTACGGATTTGATCTCGTAAAGCAAC
TGGCCGACGGACGAATGTGGCACGAATCTGGACATTTCCCCCGGATAACA
ATGTGTGATTTCGAAATTCGCAAGTTGGCTAATAAACACCGCTACACAGT
TCAATGTGTTTTACCAATCAACATGTTTAATGAGAAAATCTTCATTTTTC
TTTGGTTTTGGTTTGTTTTAGTTTCCGCCGTTACCGTGAGCAGTTTCATA
TCATTGACTTACAAAATCGGTTTGGTTTATAATCGAATTAATTTTGTTTG
TAAATTTCTCAAGTTGCGCCAGAAACCAGAAACAATAACGAAAAACAAAT
GTCGGAACTTTGTCGAAAAGCATTTACGACATGATGGAGTGTTTTTGTTG
CGACTTTTGGCTCAGAACGCCGGTGACTTGATCGCCTCAGAAATTACTGA
CTCTCTTTGGCGATTGTATAGCGACCATAAATCAGAAACCAAAACCGATT
TGTTTCGTTCGAAAGAAAACCATCGAAATTTAGCTTCTGGTCAGCAGATT
TTGACCCACAAACCTCAACTTAACGAATCGTTGCTTTCGTTAAGGAAAGA
TTCCTCGTCACACACAAAAATCAGAGGTCCTGATAAATCCCGCCATAAGC
TGCCTTTAAATGAATTCGCTACCGCTAATCCGACTGCCGAGGAAGATCCT
GGGGAATTTGTTTAAAGAACTGATTTTTATAAAAATTAAAAGTCGAGCCC
GTTGGAATTATAAATGTGATAATAGTTTTGATGAAAGATTTCCGTTTTTA
CGATTAAAAAGCTATTCGGAAAATATTC
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protein sequence of SMED30033065-orf-1

>SMED30033065-orf-1 ID=SMED30033065-orf-1|Name=SMED30033065-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=481bp
MVRSRNFDQFASLNMESQLFAGLSKFKWYAGRFMRDDDFADRLNHTFTSF
LLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPG
VHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGIN
LVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMR
NFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYT
FYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPIN
MFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQ
KPETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYS
DHKSETKTDLFRSKENHRNLASGQQILTHKPQLNESLLSLRKDSSSHTKI
RGPDKSRHKLPLNEFATANPTAEEDPGEFV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 223..237
score: 43.73
coord: 295..311
score: 74.12
coord: 271..280
score: 68.8
coord: 60..71
score: 53.67
coord: 88..97
score: 47.2
coord: 118..140
score: 58.09
IPR000990InnexinPFAMPF00876Innexincoord: 37..399
e-value: 3.0E-121
score: 405.0
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 33..417
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 32..405
score: 36.591
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 442..461
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 440..480
NoneNo IPR availableTMHMMTMhelixcoord: 43..65
NoneNo IPR availableTMHMMTMhelixcoord: 219..241
NoneNo IPR availableTMHMMTMhelixcoord: 121..143
NoneNo IPR availableTMHMMTMhelixcoord: 306..328