Protein FAM76B

Overview
NameProtein FAM76B
Smed IDSMED30033046
Length (bp)1801
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein FAM76B (SMED30033046) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein FAM76B (SMED30033046) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein FAM76B (SMED30033046) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein FAM76B (SMED30033046) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033046

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30033046h1SMcG0007734 dd_Smed_v4_6213_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30033046h1SMcG0007734 dd_Smed_v4_6213_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033046h1SMcG0007734 dd_Smed_v4_6213_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein FAM76B vs. Ensembl Human
Match: FAM76A (family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530])

HSP 1 Score: 111.694 bits (278), Expect = 1.700e-26
Identity = 88/294 (29.93%), Postives = 140/294 (47.62%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTL 885
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+ S    +  ++   LS     +S  +L ++    E   K+S+ E    N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++  +  +  QM+   +   E L  K R L
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL-SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNREL 285
[Close]
BLAST of Protein FAM76B vs. Ensembl Human
Match: FAM76B (family with sequence similarity 76 member B [Source:HGNC Symbol;Acc:HGNC:28492])

HSP 1 Score: 112.079 bits (279), Expect = 2.284e-26
Identity = 88/328 (26.83%), Postives = 151/328 (46.04%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSD------------------KNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK    K  +  K       ++ S+ LT+                      + ++S+LS         ++  +++ +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M+   +   E L  K R L ++   + +  K
Sbjct:    5 ALYACTKCTQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKK 328
[Close]
BLAST of Protein FAM76B vs. Ensembl Human
Match: FAM76B (family with sequence similarity 76 member B [Source:HGNC Symbol;Acc:HGNC:28492])

HSP 1 Score: 111.309 bits (277), Expect = 3.381e-26
Identity = 88/328 (26.83%), Postives = 153/328 (46.65%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSD------------------KNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK    K  +  K       ++ S+ LT+                      + ++S+LS         ++  +++ +  E   K+ ++E      D+S++  + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M+   +   E L  K R L ++   + +  K
Sbjct:    5 ALYACTKCTQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSINQ-SADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKK 327
[Close]
BLAST of Protein FAM76B vs. Ensembl Human
Match: FAM76A (family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530])

HSP 1 Score: 108.612 bits (270), Expect = 1.040e-25
Identity = 83/291 (28.52%), Postives = 132/291 (45.36%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINI 906
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+          +  + S LS     NS                 L++   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++  +  +  QM+   +   E L  K R L ++   +
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHLSSSSRA----GHQEKEQYSRLSGGGHYNSF-------------SPDLAL---DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAAL 263
[Close]
BLAST of Protein FAM76B vs. Ensembl Human
Match: FAM76A (family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530])

HSP 1 Score: 107.842 bits (268), Expect = 1.998e-25
Identity = 85/287 (29.62%), Postives = 137/287 (47.74%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENL 864
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+ S    +  ++   LS     +S  +L ++    E   K+S+ E    N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++  +  +  QM+   +   E L
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL-SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 278
[Close]
BLAST of Protein FAM76B vs. Ensembl Celegans
Match: K04F10.7 (pep chromosome:WBcel235:I:6366331:6368078:1 gene:WBGene00019399.1 transcript:K04F10.7.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K04F10.7)

HSP 1 Score: 56.6102 bits (135), Expect = 1.501e-8
Identity = 35/110 (31.82%), Postives = 51/110 (46.36%), Query Frame = 1 
Query:  148 KQCFYCNSDF-KNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAI 474
            K+CF C     +++I   +C KC  +  K+G+P  C  CK+   F +   C+ CSH   KFG+P  C N C+ S  F    S +     +LC LC    +     V   I
Sbjct:    7 KKCFNCRVALPEDAINTAQCQKCQKNEAKYGKPGTCQYCKLNAAFHDQK-CVWCSHAERKFGNPFPCAN-CKLSCAFPRRESDKVEGAALLCRLCILQARHTNQTVVAGI 114
[Close]
BLAST of Protein FAM76B vs. Ensembl Fly
Match: CG4452 (gene:FBgn0035981 transcript:FBtr0089493)

HSP 1 Score: 138.658 bits (348), Expect = 1.355e-35
Identity = 95/315 (30.16%), Postives = 160/315 (50.79%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGD-KCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKN-----------IELSSLSRNDSTNSLLSAEPISKRSRIEDN--------SLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKK 927
            L+ C KCF +    ELS+  QLC+ C+    STS  +C YC S+F+ +      C KC  +L K+G+PS C  CK+   FG +  CMRC+ Y +K+G P QC+ C   SAF +     +KVNGK+LCWLC   YK     + KA ++  + +   +  + T SS ++           +  S    N+S  + +S   +    +I           + +    D+  ++ ++ +  L+E I +L +++  KD ELL KD  +  LK    +K+ D+ NR  +++   + + +NL  KI ++ +E   + ++S KK
Sbjct:    6 LFACSKCFSRHLYEELSSGQQLCKGCRG---STSVGKCTYCRSEFQPATKSQSACKKCEHYLGKYGKPSACECCKIVAAFGGSK-CMRCASYEAKYGPPVQCDECKLRSAFDRRD-ENKKVNGKLLCWLCACAYKRA---LLKAQQEGRIPMSKKRPHEKTSSSHRDSAAAKKPSRNELGKSGSGANNSGVNAVSGAGLDLPDKISRGNGGNGTIAAPAAITVDTNSSDHVVAITYLKERIASLEKRLNQKDKELLEKDKQLTELKGKNFEKENDMRNRLKEVERLHDMKVDNLNRKIASVLKELAVLKKSSNKK 312
[Close]
BLAST of Protein FAM76B vs. Ensembl Fly
Match: CG4452 (gene:FBgn0035981 transcript:FBtr0333883)

HSP 1 Score: 65.4698 bits (158), Expect = 3.023e-12
Identity = 36/88 (40.91%), Postives = 50/88 (56.82%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGG-DKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMR 303
            L+ C KCF +    ELS+  QLC+ C+    STS  +C YC S+F+ +      C KC  +L K+G+PS C  CK+   FG +  CMR
Sbjct:    6 LFACSKCFSRHLYEELSSGQQLCKGCRG---STSVGKCTYCRSEFQPATKSQSACKKCEHYLGKYGKPSACECCKIVAAFGGSK-CMR 89
[Close]
BLAST of Protein FAM76B vs. Ensembl Zebrafish
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:335015])

HSP 1 Score: 107.842 bits (268), Expect = 3.225e-25
Identity = 82/273 (30.04%), Postives = 128/273 (46.89%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK-VFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA-------------EPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADI 789
             LY C KC Q+F   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+  LQK+K   K +   + +  S    +  +    +      S +   +  LS              E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD 
Sbjct:    5 ALYACTKCNQRFPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKDEGRRKVDGKLLCWLCTLSYRRVLQKTKEQRKGLGSSHSNSSSLSEKEHQRHHHHHQHHRHGSSHHKISGNLSPEQDQGLWKQSIQKETPKKKPKLETKPSNGDSSSITQSMDSGGTDNFILISQLKEEVMSLKRMLQQRDQTILEKDRKLTELKADF 273
[Close]
BLAST of Protein FAM76B vs. Ensembl Xenopus
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:548701])

HSP 1 Score: 119.013 bits (297), Expect = 4.362e-29
Identity = 88/304 (28.95%), Postives = 151/304 (49.67%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK-VFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K   K++   + +  S+  T+  +   K+        +  +++++  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M    ++  E L  K R L ++   + +  K
Sbjct:    4 ALYACTKCHQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHSHKSSTVIQNETPKKKPKLEFKPSNGDSSSINQSTDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKK 303
[Close]
BLAST of Protein FAM76B vs. Ensembl Xenopus
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:548701])

HSP 1 Score: 115.546 bits (288), Expect = 1.202e-27
Identity = 89/323 (27.55%), Postives = 151/323 (46.75%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSKVFK---------------AIKDKNVDIFSNKSTDLTKSSD-----KNIELSSLSRNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K  +                 KD++     +      + S+     K  E     ++  +++++  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M    ++  E L  K R L ++   + +  K
Sbjct:    4 ALYACTKCHQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSNTVNTLKEPEQGIWKQSHKSSTVIQNETPKKKPKLEFKPSNGDSSSINQSTDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKK 322
[Close]
BLAST of Protein FAM76B vs. Ensembl Xenopus
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:548701])

HSP 1 Score: 112.464 bits (280), Expect = 1.341e-26
Identity = 91/327 (27.83%), Postives = 155/327 (47.40%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSKVFK---------------AIKDKNVDIFSNKSTDLTKSSDKNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K  +                 KD++     +      + S  + ++SSLS         ++  +++++  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M    ++  E L  K R L ++   + +  K
Sbjct:    4 ALYACTKCHQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSSSHHKISSLSPEPEQGIWKQSHKSSTVIQNETPKKKPKLEFKPSNGDSSSINQSTDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKK 326
[Close]
BLAST of Protein FAM76B vs. Ensembl Xenopus
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:548701])

HSP 1 Score: 112.079 bits (279), Expect = 1.875e-26
Identity = 91/327 (27.83%), Postives = 157/327 (48.01%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSKVFK---------------AIKDKNVDIFSNKSTDLTKSSDKNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K  +                 KD++     +      + S  + ++SSLS         ++  +++++  E   K+ ++E      D+S++  + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M    ++  E L  K R L ++   + +  K
Sbjct:    4 ALYACTKCHQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSSSHHKISSLSPEPEQGIWKQSHKSSTVIQNETPKKKPKLEFKPSNGDSSINQ-STDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKK 325
[Close]
BLAST of Protein FAM76B vs. Ensembl Mouse
Match: Fam76a (family with sequence similarity 76, member A [Source:MGI Symbol;Acc:MGI:2385211])

HSP 1 Score: 112.464 bits (280), Expect = 5.165e-27
Identity = 89/294 (30.27%), Postives = 140/294 (47.62%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTL 885
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+ S    +  ++   LS  S  +S  +L ++    E   K+S+ E    N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++     +  QM+   +   E L  K R L
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL-SSSSRGSHQEKEQYSRLSGGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNREL 285
[Close]
BLAST of Protein FAM76B vs. Ensembl Mouse
Match: Fam76b (family with sequence similarity 76, member B [Source:MGI Symbol;Acc:MGI:1920076])

HSP 1 Score: 112.849 bits (281), Expect = 8.052e-27
Identity = 89/328 (27.13%), Postives = 151/328 (46.04%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSD------------------KNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK    K  +  K       ++ S+ LT+                      + ++SSLS         ++  +++ +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M+   +   E L  K R L ++   + +  K
Sbjct:    5 ALYACTKCTQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHSSGHHKVSSLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKK 328
[Close]
BLAST of Protein FAM76B vs. Ensembl Mouse
Match: Fam76a (family with sequence similarity 76, member A [Source:MGI Symbol;Acc:MGI:2385211])

HSP 1 Score: 108.997 bits (271), Expect = 5.351e-26
Identity = 84/291 (28.87%), Postives = 132/291 (45.36%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINI 906
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   +    S+    S  +  + S LS     NS                 L++   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++     +  QM+   +   E L  K R L ++   +
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL----SSSSRGSHQEKEQYSRLSGGSHYNSF-------------SPDLAL---DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAAL 263
[Close]
BLAST of Protein FAM76B vs. Ensembl Mouse
Match: Fam76b (family with sequence similarity 76, member B [Source:MGI Symbol;Acc:MGI:1920076])

HSP 1 Score: 98.5969 bits (244), Expect = 7.578e-23
Identity = 57/143 (39.86%), Postives = 77/143 (53.85%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK 459
             LY C KC Q++   ELS   QLC+ C+         +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K
Sbjct:    5 ALYACTKCTQRYPFEELSQGQQLCKECRIAHPIV---KCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTK 143
[Close]
BLAST of Protein FAM76B vs. Ensembl Mouse
Match: Fam76a (family with sequence similarity 76, member A [Source:MGI Symbol;Acc:MGI:2385211])

HSP 1 Score: 68.9366 bits (167), Expect = 1.525e-13
Identity = 43/107 (40.19%), Postives = 61/107 (57.01%), Query Frame = 1 
Query:  151 QCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK 459
            +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K
Sbjct:   20 KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYKRVLQKTK 123
[Close]
BLAST of Protein FAM76B vs. UniProt/SwissProt
Match: sp|Q5ZJ65|FA76A_CHICK (Protein FAM76A OS=Gallus gallus OX=9031 GN=FAM76A PE=2 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 4.064e-28
Identity = 95/316 (30.06%), Postives = 153/316 (48.42%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSR---IEDNSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGL 951
             LY C KC Q+F    LS   QLC+ C+         +C YC ++F+  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+    L +  ++   LSS S  +S  +L ++    E   K+++   I  N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD+  ++  +  +  QM+   +   E L  K R L ++   +   SK K+P  S  +
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPIV---KCTYCRTEFQQESKTNTICKKCAQNVKLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPHSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQCKHLSSSSRASL-QEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKAKFDAISANGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADLQYQESQMRAKMNQMEKTHKEVMEQLQAKNRELLKQAAAL---SKGKKPEKSGAI 304
[Close]
BLAST of Protein FAM76B vs. UniProt/SwissProt
Match: sp|Q922G2|FA76A_MOUSE (Protein FAM76A OS=Mus musculus OX=10090 GN=Fam76a PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.613e-26
Identity = 89/294 (30.27%), Postives = 140/294 (47.62%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTL 885
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+ S    +  ++   LS  S  +S  +L ++    E   K+S+ E    N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++     +  QM+   +   E L  K R L
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL-SSSSRGSHQEKEQYSRLSGGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNREL 285
[Close]
BLAST of Protein FAM76B vs. UniProt/SwissProt
Match: sp|Q5EA89|FA76A_BOVIN (Protein FAM76A OS=Bos taurus OX=9913 GN=FAM76A PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.939e-26
Identity = 89/294 (30.27%), Postives = 140/294 (47.62%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVF-GNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSA----EPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTL 885
             LY C KC Q+F    LS   QLC+ C+         +C YC ++++  S     C KC  +++ +G P  C  C +   F GN   C RC++   K+G P  CE C Q  AF +    R+KV+GK+LCWLCT  YK    +V +  K++   + S+ S       ++   LS  S  +S  +L ++    E   K+S+ E    N  S   +   DS   +  + +  L+EE+  L++ +  KD  +L K+  I  LKAD   ++  +  +  QM+   +   E L  K R L
Sbjct:    3 ALYACTKCHQRFPFEALSQGQQLCKECRIAHPVV---KCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNK--CQRCTNSEKKYGPPYSCEQCKQQCAFDRKD-DRKKVDGKLLCWLCTLSYK----RVLQKTKEQRKHL-SSSSRASHHEKEQYSRLSGGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNREL 285
[Close]
BLAST of Protein FAM76B vs. UniProt/SwissProt
Match: sp|Q80XP8|FA76B_MOUSE (Protein FAM76B OS=Mus musculus OX=10090 GN=Fam76b PE=1 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 5.632e-26
Identity = 89/328 (27.13%), Postives = 151/328 (46.04%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSD------------------KNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK    K  +  K       ++ S+ LT+                      + ++SSLS         ++  +++ +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M+   +   E L  K R L ++   + +  K
Sbjct:    5 ALYACTKCTQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGAPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHSKHHHHHHHHHHRHSSGHHKVSSLSPEQEQGLWKQSHKSSAAIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKK 328
[Close]
BLAST of Protein FAM76B vs. UniProt/SwissProt
Match: sp|Q566M1|FA76B_XENTR (Protein FAM76B OS=Xenopus tropicalis OX=8364 GN=fam76b PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 7.104e-26
Identity = 91/327 (27.83%), Postives = 155/327 (47.40%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSKVFK---------------AIKDKNVDIFSNKSTDLTKSSDKNIELSSLS---------RNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+    +    +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  YK  LQK+K  +                 KD++     +      + S  + ++SSLS         ++  +++++  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +   M    ++  E L  K R L ++   + +  K
Sbjct:    4 ALYACTKCHQRYPFEELSQGQQLCKECRI---AHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSSSHHKISSLSPEPEQGIWKQSHKSSTVIQNETPKKKPKLEFKPSNGDSSSINQSTDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKK 326
[Close]
BLAST of Protein FAM76B vs. TrEMBL
Match: A0A5K3EY51 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 246.128 bits (627), Expect = 2.646e-71
Identity = 149/351 (42.45%), Postives = 208/351 (59.26%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNS----------LSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKS-RWENEREN-LMDKIRTLQRENINI--MRNSKKKRPLPSSGLQYLTRNPL-------PVMPHSVTDSPEVSRGGSA 1032
            L+ C KC + F  S++S     C+ C  T + +S+KQC YC +DFK S+ G  CP+C S   K+GEP  CTIC + M +G+A++C RC HYR+KFGDPQQC+ C Q  AF+KD +SR KV+GK+LCW+CTY YK+ KSK               + +D ++S   +++ + + R+   +S LSA    +R R ED +           + Y+ DS YNE LL ++ LQ++IK L+RK+A KD ELLAKD +IAGLK+D+   D +   RE   KS R   E  N L D IR LQRE   +  +R+SKK+R    SG   LT +PL        VMP SV+ +P + R  +A
Sbjct:    5 LFSCTKCLKSFPHSQMSRSGTTCKIC--TPHHSSFKQCEYCRADFKQSLPGTICPRCQSSKTKYGEPKPCTICLLPMAYGSALVCQRCLHYRNKFGDPQQCQKCLQICAFYKDEVSRSKVDGKILCWVCTYDYKIAKSK---------------ERSDRSQSKRNSLDDAFMPRSSRDSSNLSA---VRRQRTEDYTSRHSANRSANTNTYSMDSAYNEHLLTISQLQDDIKILKRKLAQKDAELLAKDRIIAGLKSDL--DDCESQKRERAFKSERMAKEEINRLKDTIRNLQREKAELSSVRSSKKRRTGGLSG-SPLTLSPLRVPPTKSAVMPTSVS-TPSLRRAAAA 331
[Close]
BLAST of Protein FAM76B vs. TrEMBL
Match: A0A564Z904 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS13343 PE=4 SV=1)

HSP 1 Score: 242.662 bits (618), Expect = 2.575e-70
Identity = 138/322 (42.86%), Postives = 197/322 (61.18%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNN-DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSR--WENERENLMDKIRTLQRENINIM--RN--SKKKRPLPSSGLQYLTRNPLPVMP 987
            ++ C +C + F  S++S     C+NC    + +S+KQC YC SDFK SI G  CP+C S   ++G+P  C+IC++ M FG+A++C RC HYRSKFGDP+QCE C Q  AF+KD  SR KVNG+VLCW+CTY YK+ KS   K   DK+     +     +KS D     SSL R  +       E IS R  +  ++ ++ ++ DS YN+ L+ ++ LQEE++NL+R +A KD ELLAKD +IAGL+AD+   D +   RE   KS+     E E L D IRTL+RE  +I+  RN  +K++R + +  L  L  +PL + P
Sbjct:    5 MFSCSRCLKSFPSSQMSRSGTFCKNC--NPHHSSFKQCDYCRSDFKRSISGSLCPRCQSLKSRYGDPKPCSICQLTMAFGSALVCQRCLHYRSKFGDPRQCEKCLQLCAFYKDEASRSKVNGQVLCWVCTYNYKVSKS---KERSDKHQSKRGSFGDSYSKSHDSQ---SSLKRQRT-------EEISGRHSLNRSANALTDSLDSAYNDHLVTISQLQEEMRNLKRALAQKDAELLAKDRVIAGLRADL--DDFETQRRERAYKSQALANEEIEKLKDTIRTLKREKADILASRNPSTKRRRAMNADSLSPLKLSPLRLPP 309
[Close]
BLAST of Protein FAM76B vs. TrEMBL
Match: A0A087W012 (Protein FAM76A OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000184600 PE=4 SV=1)

HSP 1 Score: 239.195 bits (609), Expect = 1.411e-68
Identity = 138/357 (38.66%), Postives = 200/357 (56.02%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRE--NINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSR---------GGSASK----DVSSAEDSPH 1068
            L+ C +C + F  S++S    +C+ C    + +S+KQC YC SDFK SI G  CP+C S   ++G+P  CTIC++ M FG+A++C RC HYR+KFGDP+QCE C    AF+KD  SR KV+G+VLCW+CTY YK+ KSK            F++  + L+KS D        S + +     + E  S+ S     + + YN DS YNE LL +  LQ++IK L+R++A KD ELLAKD +IAGLK+D+   +     R  + +     E E L + IRTL+RE   ++  R + KKR + +     LT +P+ V P     +  VS          GGSA+     D +++   PH
Sbjct:    5 LFSCTRCLKNFPSSQMSRSGTICKAC--NPHHSSFKQCEYCRSDFKQSISGAICPRCCSLKSRYGDPKSCTICQLPMAFGSALVCQRCLHYRTKFGDPRQCEKCLHMCAFYKDEASRSKVDGQVLCWVCTYNYKMSKSKERSEKHQSKRSSFND--SYLSKSHDS-------SNSGAIKRQRTEEYTSRHSSNRPGNAANYNMDSAYNEHLLTIGQLQDDIKALKRQLAQKDAELLAKDKMIAGLKSDLDDYESQQRERAFKTQHIANEEIERLKETIRTLKREKAELSASRFTSKKRRIVAHTGSPLTLSPIRVPPKPAKLTTSVSTPNAVFHHSGGGSAAAKEAGDNTASPTPPH 350
[Close]
BLAST of Protein FAM76B vs. TrEMBL
Match: A0A5K3EVH4 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 236.113 bits (601), Expect = 7.498e-68
Identity = 142/341 (41.64%), Postives = 197/341 (57.77%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKS-RWENEREN-LMDKIRTLQRENINI--MRNSKKKRPLPSSGLQYLTRNPL-------PVMPHSVTDSPEVSRGGSA 1032
            L+ C KC + F  S++S     C+ C  T + +S+KQC YC +DFK S+ G  CP+C S   K+GEP  CTIC + M +G+A++C RC HYR+KFGDPQQC+ C Q  AF+KD +SR KV+GK+LCW+CTY YK+ KSK               + +D ++S   +++ + + R+   +S                     N DS YNE LL ++ LQ++IK L+RK+A KD ELLAKD +IAGLK+D+   D +   RE   KS R   E  N L D IR LQRE   +  +R+SKK+R    SG   LT +PL        VMP SV+ +P + R  +A
Sbjct:    5 LFSCTKCLKSFPHSQMSRSGTTCKIC--TPHHSSFKQCEYCRADFKQSLPGTICPRCQSSKTKYGEPKPCTICLLPMAYGSALVCQRCLHYRNKFGDPQQCQKCLQICAFYKDEVSRSKVDGKILCWVCTYDYKIAKSK---------------ERSDRSQSKRNSLDDAFMPRSSRDSS---------------------NMDSAYNEHLLTISQLQDDIKILKRKLAQKDAELLAKDRIIAGLKSDL--DDCESQKRERAFKSERMAKEEINRLKDTIRNLQREKAELSSVRSSKKRRTGGLSG-SPLTLSPLRVPPTKSAVMPTSVS-TPSLRRAAAA 303
[Close]
BLAST of Protein FAM76B vs. TrEMBL
Match: A0A564Z7V1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS13343 PE=4 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 1.446e-66
Identity = 146/359 (40.67%), Postives = 205/359 (57.10%), Query Frame = 1 
Query:   43 LYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSK-----------VFKAIKDKNVDIFS----------------NKSTD-LTKSSD--KNIELSSLSR-----NDSTNSLLSAE---PISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSR--WENERENLMDKIRTLQRENINIM--RN--SKKKRPLPSSGLQYLTRNPLPVMP 987
            ++ C +C + F  S++S     C+NC    + +S+KQC YC SDFK SI G  CP+C S   ++G+P  C+IC++ M FG+A++C RC HYRSKFGDP+QCE C Q  AF+KD  SR KVNG+VLCW+CTY YK+ KSK            F     K+ D  S                N+S + LT S +   NIE ++L       ND+   L  ++   PI   S  ++ SL     DS YN+ L+ ++ LQEE++NL+R +A KD ELLAKD +IAGL+AD+   D +   RE   KS+     E E L D IRTL+RE  +I+  RN  +K++R + +  L  L  +PL + P
Sbjct:    5 MFSCSRCLKSFPSSQMSRSGTFCKNC--NPHHSSFKQCDYCRSDFKRSISGSLCPRCQSLKSRYGDPKPCSICQLTMAFGSALVCQRCLHYRSKFGDPRQCEKCLQLCAFYKDEASRSKVNGQVLCWVCTYNYKVSKSKERSDKHQSKRGSFGDSYSKSHDSQSSLKRQRTEEISGRHSLNRSANALTDSGEPSSNIESAALLYIRQLLNDAAKRLAESDSKSPIRPLSENKNPSL-----DSAYNDHLVTISQLQEEMRNLKRALAQKDAELLAKDRVIAGLRADL--DDFETQRRERAYKSQALANEEIEKLKDTIRTLKREKADILASRNPSTKRRRAMNADSLSPLKLSPLRLPP 354
[Close]
BLAST of Protein FAM76B vs. Ensembl Cavefish
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:335015])

HSP 1 Score: 87.0409 bits (214), Expect = 2.334e-18
Identity = 65/225 (28.89%), Postives = 111/225 (49.33%), Query Frame = 1 
Query:  151 QCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE-----------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADI 789
            +C YC ++F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+    +V +  K++   +  +  ++ +  SDK  E     R+ S++    +  I K +  +           D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD 
Sbjct:   41 KCTYCRTEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYR----RVLQKTKEQRKGL-GSSHSNTSSLSDK--EHRHHHRHSSSHHNHKSSSIQKETPKKKPKLELKPSNGDSSSVAQSMDSGGTDNFILISQLKEEVMSLKRMLQQRDQTILEKDRKLTELKADF 257
[Close]
BLAST of Protein FAM76B vs. Ensembl Cavefish
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:335015])

HSP 1 Score: 85.8853 bits (211), Expect = 7.002e-18
Identity = 68/238 (28.57%), Postives = 107/238 (44.96%), Query Frame = 1 
Query:  154 CFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK-----------VFKAIKDKNVDIFSNKSTDLTKSS------------DKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADI 789
            C YC ++F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+  LQK+K              ++ DK        S+   K S            D++ + SS+ +             S      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD 
Sbjct:   42 CTYCRTEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYRRVLQKTKEQRKGLGSSHSNTSSLSDKEHRHHHRHSSSHHKLSGSLSPEQEQRLWDQSHKSSSIQKETPKKKPKLELKPSN----GDSSSVAQSMDSGGTDNFILISQLKEEVMSLKRMLQQRDQTILEKDRKLTELKADF 274
[Close]
BLAST of Protein FAM76B vs. Ensembl Sea Lamprey
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:335015])

HSP 1 Score: 105.531 bits (262), Expect = 4.306e-25
Identity = 88/339 (25.96%), Postives = 154/339 (45.43%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYK--LQKSK---------VFKAIKDKNVDIFSNKSTD------------------LTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIED---NSLSMYNN---DSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKR-PLPSS 945
             LY C KC Q+F   ELS   QLC++C+         +C YC ++F+  S     C KC  +++ +G P  C  C +   F     C RC++   K+G P  CE C Q  AF +   S++KV+GK+LCWLCT  Y+  LQK+K           ++ +D+       + T                    +  S  +I     + + S       +P  K+ ++E+   N  S+  +   DS  ++  + +  L+EE+  L++++  K+  +L +D  +  +KAD   ++  I  +   M+   +   E L  K R L ++  ++ +  K  R P+ +S
Sbjct:    5 ALYACTKCHQRFPFEELSQSQQLCKDCRIAHPVV---KCTYCRTEFQQESKTNTICKKCAQNVKLYGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGLPLACEQCKQRCAFDRKDDSKKKVDGKLLCWLCTLSYRRVLQKAKEQHRGLGAAQHRSSQDERHGARKEQHTHRQYVQAHSSHSMHSTHHSASAHSTLHIASKQNTHHKSPGPASQNDPPQKKPKVENKPSNGDSVSGDATMDSASSDNFILITQLKEEVALLKKQLQQKEGLILERDRKLTEIKADFQYQENLIRTKMNNMERTHKESIEQLQSKNRELIKQVSSLSKGKKLDRAPVGTS 339
[Close]
BLAST of Protein FAM76B vs. Ensembl Nematostella
Match: EDO46673 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPE7])

HSP 1 Score: 108.612 bits (270), Expect = 3.292e-26
Identity = 90/330 (27.27%), Postives = 153/330 (46.36%), Query Frame = 1 
Query:   37 FGLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFK--NSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKL----QKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSL-SMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDS 1005
              L+ C KC  +    ELS   QLC+ C+    S     C +C  +F   +      C KC S+++++G+P+ C  C ++  F N   C RC     K+G P  CE C    AF K   S++KV+GKVLC LCT  YK      K KV      ++  +   K +      +K  +++ L  +  ++      P++       +S  S    +++ + Q+ ++N L+E++  L+R++  KD  LL K+  +  LKA+  +K+K    + + +       ++ + D+I TLQ EN N+ +            L  L+R P P    + T S
Sbjct:    1 MSLFACTKCHSRHPFEELSRGDQLCKKCRK---SFPLVTCTFCRLEFHLLDKTERPVCKKCDSNIKQYGQPTCCVYCNIRAAF-NGDKCSRCESSEKKYGTPVLCEQCKLKCAFKKSDESKEKVDGKVLCLLCTLSYKRLVHKSKGKVHGRSSSQHKGV---KRSHHHPKHEKKSKVAKLQESKQSSQSSRDSPVTALGLYSASSGNSDTGGEAIMSGQMAELNDLKEQVAKLKRQLQQKDQALLEKEKKLTELKAENWEKEKVSKKKVMSL-------QKEMTDRIDTLQTENRNLRKQ-----------LSSLSRTPKPEKASASTAS 305
[Close]
BLAST of Protein FAM76B vs. Ensembl Medaka
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:101157078])

HSP 1 Score: 114.39 bits (285), Expect = 1.650e-27
Identity = 87/331 (26.28%), Postives = 146/331 (44.11%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTK------------------------------SSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+         +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+    +V +  K++     S+ S+ L +                               S    +   L +    +S +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +  QM+   +   E    K R L ++   + +  K
Sbjct:    7 ALYACTKCNQRYPFEELSQGQQLCKECRIAHPIV---KCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYR----RVLQKTKEQRKGFVSSNSSSLNEKDHHSRTHHHHHHHQPHHHHRHSSSHHKLSGSLSPEQEPGLWKQSHKSSSIQKETPKKKPKLEMKPSNGDSSSITQSMDSGGTDNFILISQLKEEVMSLKRLLQQRDQTILEKDRKLTELKADFQYQESNMRVKMNQMEKAHKEAMEQQQGKNRELMKQVAALSKGKK 329
[Close]
BLAST of Protein FAM76B vs. Ensembl Medaka
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:101157078])

HSP 1 Score: 114.39 bits (285), Expect = 1.650e-27
Identity = 87/331 (26.28%), Postives = 146/331 (44.11%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTK------------------------------SSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+         +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+    +V +  K++     S+ S+ L +                               S    +   L +    +S +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +  QM+   +   E    K R L ++   + +  K
Sbjct:    7 ALYACTKCNQRYPFEELSQGQQLCKECRIAHPIV---KCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYR----RVLQKTKEQRKGFVSSNSSSLNEKDHHSRTHHHHHHHQPHHHHRHSSSHHKLSGSLSPEQEPGLWKQSHKSSSIQKETPKKKPKLEMKPSNGDSSSITQSMDSGGTDNFILISQLKEEVMSLKRLLQQRDQTILEKDRKLTELKADFQYQESNMRVKMNQMEKAHKEAMEQQQGKNRELMKQVAALSKGKK 329
[Close]
BLAST of Protein FAM76B vs. Ensembl Medaka
Match: fam76b (family with sequence similarity 76 member B [Source:NCBI gene;Acc:101157078])

HSP 1 Score: 112.849 bits (281), Expect = 2.580e-27
Identity = 84/301 (27.91%), Postives = 140/301 (46.51%), Query Frame = 1 
Query:   40 GLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKN-SIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE------DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSK 921
             LY C KC Q++   ELS   QLC+ C+         +C YC S+F+  S     C KC  ++++ G P  C  C +   F     C RC++   K+G PQ CE C Q  AF +    R+KV+GK+LCWLCT  Y+    +V +  K++     S+ S+                     +S +  E   K+ ++E      D+S    + DS   +  + ++ L+EE+ +L+R +  +D  +L KD  +  LKAD   ++ ++  +  QM+   +   E    K R L ++   + +  K
Sbjct:    5 ALYACTKCNQRYPFEELSQGQQLCKECRIAHPIV---KCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAF-IGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYR----RVLQKTKEQRKGFVSSNSS-------------------HKSSSIQKETPKKKPKLEMKPSNGDSSSITQSMDSGGTDNFILISQLKEEVMSLKRLLQQRDQTILEKDRKLTELKADFQYQESNMRVKMNQMEKAHKEAMEQQQGKNRELMKQVAALSKGKK 278
[Close]
BLAST of Protein FAM76B vs. Planmine SMEST
Match: SMESG000071772.1 (SMESG000071772.1)

HSP 1 Score: 717.998 bits (1852), Expect = 0.000e+0
Identity = 348/348 (100.00%), Postives = 348/348 (100.00%), Query Frame = 1 
Query:   25 MTTNFGLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH 1068
            MTTNFGLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH
Sbjct:    1 MTTNFGLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH 348
[Close]
BLAST of Protein FAM76B vs. Planmine SMEST
Match: SMESG000071772.1 (SMESG000071772.1)

HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0
Identity = 323/323 (100.00%), Postives = 323/323 (100.00%), Query Frame = 1 
Query:  100 MQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH 1068
            MQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH
Sbjct:    1 MQLCQNCKNTSNSTSYKQCFYCNSDFKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSKFGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAIKDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIEDNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAGLKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKKKRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH 323
The following BLAST results are available for this feature:
BLAST of Protein FAM76B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FAM76A1.700e-2629.93family with sequence similarity 76 member A [Sourc... [more]
FAM76B2.284e-2626.83family with sequence similarity 76 member B [Sourc... [more]
FAM76B3.381e-2626.83family with sequence similarity 76 member B [Sourc... [more]
FAM76A1.040e-2528.52family with sequence similarity 76 member A [Sourc... [more]
FAM76A1.998e-2529.62family with sequence similarity 76 member A [Sourc... [more]
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BLAST of Protein FAM76B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
K04F10.71.501e-831.82pep chromosome:WBcel235:I:6366331:6368078:1 gene:W... [more]
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BLAST of Protein FAM76B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG44521.355e-3530.16gene:FBgn0035981 transcript:FBtr0089493[more]
CG44523.023e-1240.91gene:FBgn0035981 transcript:FBtr0333883[more]
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BLAST of Protein FAM76B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fam76b3.225e-2530.04family with sequence similarity 76 member B [Sourc... [more]
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BLAST of Protein FAM76B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
fam76b4.362e-2928.95family with sequence similarity 76 member B [Sourc... [more]
fam76b1.202e-2727.55family with sequence similarity 76 member B [Sourc... [more]
fam76b1.341e-2627.83family with sequence similarity 76 member B [Sourc... [more]
fam76b1.875e-2627.83family with sequence similarity 76 member B [Sourc... [more]
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BLAST of Protein FAM76B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fam76a5.165e-2730.27family with sequence similarity 76, member A [Sour... [more]
Fam76b8.052e-2727.13family with sequence similarity 76, member B [Sour... [more]
Fam76a5.351e-2628.87family with sequence similarity 76, member A [Sour... [more]
Fam76b7.578e-2339.86family with sequence similarity 76, member B [Sour... [more]
Fam76a1.525e-1340.19family with sequence similarity 76, member A [Sour... [more]
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BLAST of Protein FAM76B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5ZJ65|FA76A_CHICK4.064e-2830.06Protein FAM76A OS=Gallus gallus OX=9031 GN=FAM76A ... [more]
sp|Q922G2|FA76A_MOUSE3.613e-2630.27Protein FAM76A OS=Mus musculus OX=10090 GN=Fam76a ... [more]
sp|Q5EA89|FA76A_BOVIN3.939e-2630.27Protein FAM76A OS=Bos taurus OX=9913 GN=FAM76A PE=... [more]
sp|Q80XP8|FA76B_MOUSE5.632e-2627.13Protein FAM76B OS=Mus musculus OX=10090 GN=Fam76b ... [more]
sp|Q566M1|FA76B_XENTR7.104e-2627.83Protein FAM76B OS=Xenopus tropicalis OX=8364 GN=fa... [more]
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BLAST of Protein FAM76B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K3EY512.646e-7142.45Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A564Z9042.575e-7042.86Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A087W0121.411e-6838.66Protein FAM76A OS=Echinococcus multilocularis OX=6... [more]
A0A5K3EVH47.498e-6841.64Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A564Z7V11.446e-6640.67Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
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BLAST of Protein FAM76B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
fam76b2.334e-1828.89family with sequence similarity 76 member B [Sourc... [more]
fam76b7.002e-1828.57family with sequence similarity 76 member B [Sourc... [more]
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BLAST of Protein FAM76B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fam76b4.306e-2525.96family with sequence similarity 76 member B [Sourc... [more]
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BLAST of Protein FAM76B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein FAM76B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO466733.292e-2627.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein FAM76B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
fam76b1.650e-2726.28family with sequence similarity 76 member B [Sourc... [more]
fam76b1.650e-2726.28family with sequence similarity 76 member B [Sourc... [more]
fam76b2.580e-2727.91family with sequence similarity 76 member B [Sourc... [more]
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BLAST of Protein FAM76B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000071772.10.000e+0100.00SMESG000071772.1[more]
SMESG000071772.10.000e+0100.00SMESG000071772.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033046 ID=SMED30033046|Name=Protein FAM76B|organism=Schmidtea mediterranea sexual|type=transcript|length=1801bp
CATTAACTTTTTGATTTTAAAATTATGACTACCAATTTTGGATTATATGG
CTGTCGTAAATGTTTTCAGAAGTTTAAATTATCCGAATTATCAAATATTA
TGCAATTGTGTCAAAATTGCAAAAATACTAGTAATTCAACATCATATAAA
CAGTGTTTTTACTGTAACAGTGATTTTAAAAACAGCATAGGCGGTGACAA
ATGTCCGAAATGTATGAGCCACTTGGAGAAGCATGGTGAACCGTCACAAT
GCACAATTTGCAAAATGCAAATGGTATTTGGAAATGCTGTCATTTGTATG
CGTTGCAGTCATTATCGATCAAAATTTGGTGATCCTCAACAATGCGAAAA
CTGTTGTCAATATTCAGCATTTTTCAAAGATAGTATAAGTCGTCAAAAAG
TTAATGGGAAAGTTTTATGTTGGCTATGTACATACTTTTATAAACTTCAG
AAGTCTAAAGTTTTTAAGGCAATTAAAGATAAAAATGTTGACATATTTTC
TAATAAATCTACGGATTTAACTAAAAGCAGTGATAAAAATATTGAATTGT
CAAGTTTATCACGCAACGATTCGACAAACAGTTTGTTGAGTGCTGAACCA
ATAAGTAAAAGATCAAGAATTGAAGATAATAGTTTGAGTATGTATAACAA
CGACAGTGTGTATAACGAGCAACTATTGAAAGTGAACGGTTTGCAAGAGG
AAATTAAAAACCTTCGGCGTAAAGTTGCCGTCAAAGACAACGAGTTGCTG
GCTAAAGACAACCTCATTGCTGGCCTGAAGGCTGACATATTACAGAAAGA
CAAAGATATCATGAACCGAGAGATCCAGATGAAAAGTAGGTGGGAAAATG
AGCGAGAAAACCTCATGGACAAAATTCGCACCCTTCAACGAGAGAATATC
AACATCATGAGAAATAGCAAAAAGAAACGGCCTTTGCCGTCATCAGGCCT
CCAATATCTCACCAGGAATCCTCTGCCCGTTATGCCTCACTCAGTTACCG
ACTCACCGGAAGTCAGTCGAGGTGGCTCTGCCAGTAAAGATGTCAGCAGC
GCAGAGGATTCACCGCATTGACAACAAATCGAATCTCCTCTATTGACAAT
GATGATGTCATTGGCTAATATTTATTGCTTGTGAATTTGATGTGAAATAA
ATTAAACAATCTTATAATTATTATTATTTGCGTGTGTTTCAATAAGCTTT
TATTTTTGTCAATTTCCAGTGGCATCGTGTGAAAATTTATTTGTGTGTAT
TTCTGATATATTGCATGTATATTATTGATTATGACACCGTTTAAATTACT
CGTCGCGTTTCGTGCTCCCAATTCGCACCCATTGCGCCAATTTATAATTG
AGTTATTATATATCATATATTAGATGAATGTCAATAATATTGTGCTTACT
GTAATCATCAATATGTTCTTTTTTAGTATTTATTATTATTACTATTAATC
ATTTCCTCAACGGAATATTTTGTACCTAAACATTTTTTAGGTGATTTATT
GAATTGTAGAATAGTGCAAATACATTTTTAACATTATCATTATTGTGTGT
GTGCGTGTGTGTGTTTGGACAGTTATTATTATTTGTGTCTGGGAAGTTTC
ATTTCACAATTATTTATTAATAAATGTTTTATATAAACGGATTTTTTGTC
GTTCTGAATTGGAATTATGTCAACAATGTAAAATATCGAAATTTGAAGAA
ATTTAGTTACATTTAATCAATTCAGTTATTTTAGTAAATGTTTCTGATGA
GGATTATGCAATGCAAATACTCATTATTGTGCACTTTCTGTGATATTTTT
T
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protein sequence of SMED30033046-orf-1

>SMED30033046-orf-1 ID=SMED30033046-orf-1|Name=SMED30033046-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=349bp
MTTNFGLYGCRKCFQKFKLSELSNIMQLCQNCKNTSNSTSYKQCFYCNSD
FKNSIGGDKCPKCMSHLEKHGEPSQCTICKMQMVFGNAVICMRCSHYRSK
FGDPQQCENCCQYSAFFKDSISRQKVNGKVLCWLCTYFYKLQKSKVFKAI
KDKNVDIFSNKSTDLTKSSDKNIELSSLSRNDSTNSLLSAEPISKRSRIE
DNSLSMYNNDSVYNEQLLKVNGLQEEIKNLRRKVAVKDNELLAKDNLIAG
LKADILQKDKDIMNREIQMKSRWENERENLMDKIRTLQRENINIMRNSKK
KRPLPSSGLQYLTRNPLPVMPHSVTDSPEVSRGGSASKDVSSAEDSPH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016607nuclear speck
GO:0005654nucleoplasm
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR032017FAM76
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 219..246
NoneNo IPR availableCOILSCoilCoilcoord: 269..303
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 302..354
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 334..354
NoneNo IPR availablePANTHERPTHR46176:SF1coord: 12..309
IPR032017FAM76 proteinPFAMPF16046FAM76coord: 13..305
e-value: 3.4E-63
score: 213.8
IPR032017FAM76 proteinPANTHERPTHR46176FAMILY NOT NAMEDcoord: 12..309