Alpha-int-3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032970 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Alpha-int-3 vs. Ensembl Human
Match: ITGA3 (integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]) HSP 1 Score: 174.096 bits (440), Expect = 2.671e-43 Identity = 223/915 (24.37%), Postives = 381/915 (41.64%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFS------EHSNESL-LGYVVDSNSHEGLIYTCAPKFLR----SHTYVKYVEGACWEFNEMFNEVEQISNQDCL----ESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSII--NTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSP-GSCQPILTMQAVLSLPTEGEQYILHMG---NVSKFKLEIQTKNIATT-----DDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVK----------------ESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACN 2684
++N+D +K N S FG+S+ + + +Y L+ GAP ++ T TGA++ CP+T DC++ + H E + LG V S G + CA ++ + + + G C+ N++E S+ D E S + E C G + + + AP +Y KG N+ R+ S Y + Y G++M VG +P +IV G+P R + ++ + L V+ G G+ +G ++ DLNNDG +L+VGAP+ G ++V+ M+Q+ P LLL S +G+S+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ G+ D+D N YPD +VGS LS H+V +R RP+I N+V +T + P D C + C++ V + + Y P+Y + T+ Y +E + RL F + V G + K ++ N + L P+ + N SLP+ + + L + + YP+L + + +T + F C P C+ L M+A +E +Q + + +V K L I N T+ D ++A T ++ L+ + P A Q++ F C L N F N + + + + + S Q +L P++L + V L ++ N++ + +++G S + E +G +K+ + + V L + +L + +P+E+S +G++LLY P GN C
Sbjct: 32 AFNLDTRFLVVKEAG-NPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRG---NDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAP--------RHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVF----MNQAGTSFPAHP-----SLLLHGP---SGSAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ-MDVDENFYPDLLVGS-LSDHIVLLRARPVI-----NIVHKTLVPRPAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEA----DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA-------------YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFV--SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV---------------------PPALLLSSVRPPGACQANETIF-CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMV----NHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVS------NGKWLLY----PTEITVHGNGSWPCR 847
BLAST of Alpha-int-3 vs. Ensembl Human
Match: ITGA3 (integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]) HSP 1 Score: 173.711 bits (439), Expect = 3.007e-43 Identity = 223/915 (24.37%), Postives = 381/915 (41.64%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFS------EHSNESL-LGYVVDSNSHEGLIYTCAPKFLR----SHTYVKYVEGACWEFNEMFNEVEQISNQDCL----ESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSII--NTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSP-GSCQPILTMQAVLSLPTEGEQYILHMG---NVSKFKLEIQTKNIATT-----DDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVK----------------ESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACN 2684
++N+D +K N S FG+S+ + + +Y L+ GAP ++ T TGA++ CP+T DC++ + H E + LG V S G + CA ++ + + + G C+ N++E S+ D E S + E C G + + + AP +Y KG N+ R+ S Y + Y G++M VG +P +IV G+P R + ++ + L V+ G G+ +G ++ DLNNDG +L+VGAP+ G ++V+ M+Q+ P LLL S +G+S+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ G+ D+D N YPD +VGS LS H+V +R RP+I N+V +T + P D C + C++ V + + Y P+Y + T+ Y +E + RL F + V G + K ++ N + L P+ + N SLP+ + + L + + YP+L + + +T + F C P C+ L M+A +E +Q + + +V K L I N T+ D ++A T ++ L+ + P A Q++ F C L N F N + + + + + S Q +L P++L + V L ++ N++ + +++G S + E +G +K+ + + V L + +L + +P+E+S +G++LLY P GN C
Sbjct: 32 AFNLDTRFLVVKEAG-NPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRG---NDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAP--------RHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVF----MNQAGTSFPAHP-----SLLLHGP---SGSAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ-MDVDENFYPDLLVGS-LSDHIVLLRARPVI-----NIVHKTLVPRPAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEA----DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA-------------YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFV--SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV---------------------PPALLLSSVRPPGACQANETIF-CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMV----NHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVS------NGKWLLY----PTEITVHGNGSWPCR 847
BLAST of Alpha-int-3 vs. Ensembl Human
Match: ITGA7 (integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]) HSP 1 Score: 169.474 bits (428), Expect = 6.928e-42 Identity = 163/561 (29.06%), Postives = 253/561 (45.10%), Query Frame = 3
Query: 57 FINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIK-YFLIGAPFDILKDSNET--TGALFSCPVTKETQDCKKF-------VFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQDCLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ------------YTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELD 1637
F + + LF V ++N+D+ K S FGFS+ + Q + + L+GAP + + TG LF+CP++ E DC + + E LG V S G I TCA ++ + +E G C+ ++ +++ + + + Q +E + C G AA S + L+ AP +Y KGLL N +S + L ++ + + Y GFS+ GK S V G+P R K V++ K + L ++ GE SG+GYS+ DLN+DG +L+VGAP+ G V+VY N + I PL RL + + +GISL +GD+N+D D+AVGAPF DG G V+IY G S ++ K SQ +EG+ + ++ +G+S+ G + D+D N YPD +VGS L+ V R RPI+ V E +A P S D L++ N G C+ L V Y + SY+ + +DY ++ D
Sbjct: 19 FGSLLVELLFSRAV---AFNLDVMGALRKEG--EPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE-WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNI----DSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAP--------RANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS----PL----RLCGSP-----DSMFGISLAVLGDLNQDGFPDIAVGAPF--DGDGKVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSG-SLDMDGNQYPDLLVGS-LADTAVLFRARPILHVSHEVSIA------PRSID-LEQPNCAGGHSVCVDLRVCFSY----IAVPSSYSPTVALDYVLDAD 531
BLAST of Alpha-int-3 vs. Ensembl Human
Match: ITGA7 (integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]) HSP 1 Score: 164.081 bits (414), Expect = 3.090e-40 Identity = 158/537 (29.42%), Postives = 242/537 (45.07%), Query Frame = 3
Query: 57 FINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIK-YFLIGAPFDILKDSNET--TGALFSCPVTKETQDCKKF-------VFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQDCLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ------------YTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYY 1565
F + + LF V ++N+D+ K S FGFS+ + Q + + L+GAP + + TG LF+CP++ E DC + + E LG V S G I TCA ++ + +E G C+ ++ +++ + + + Q +E + C G AA S + L+ AP +Y KGLL N +S + L ++ + + Y GFS+ GK S V G+P R K V++ K + L ++ GE SG+GYS+ DLN+DG +L+VGAP+ G V+VY N + I PL RL + + +GISL +GD+N+D D+AVGAPF DG G V+IY G S ++ K SQ +EG+ + ++ +G+S+ G + D+D N YPD +VGS L+ V R RPI+ V E +A P S D L++ N G C+ L V Y
Sbjct: 19 FGSLLVELLFSRAV---AFNLDVMGALRKEG--EPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE-WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNI----DSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAP--------RANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS----PL----RLCGSP-----DSMFGISLAVLGDLNQDGFPDIAVGAPF--DGDGKVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSG-SLDMDGNQYPDLLVGS-LADTAVLFRARPILHVSHEVSIA------PRSID-LEQPNCAGGHSVCVDLRVCFSY 511
BLAST of Alpha-int-3 vs. Ensembl Human
Match: ITGA7 (integrin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:6143]) HSP 1 Score: 159.844 bits (403), Expect = 7.198e-39 Identity = 155/528 (29.36%), Postives = 237/528 (44.89%), Query Frame = 3
Query: 165 SFFGFSLNIFTSKQNSIK-YFLIGAPFDILKDSNET--TGALFSCPVTKETQDCKKF-------VFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQDCLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------------LINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELD 1637
S FGFS+ + Q + + L+GAP + + TG LF+CP++ E DC + + E LG V S G I TCA ++ + +E G C+ ++ +++ + + + Q +E + C G AA S + L+ AP +Y KG L + + + L +NS Y GFS+ GK S V G+P R K V++ K + L ++ GE SG+GYS+ DLN+DG +L+VGAP+ G V+VY N + I PL RL + + +GISL +GD+N+D D+AVGAPF DG G V+IY G S ++ K SQ +EG+ + ++ +G+S+ G + D+D N YPD +VGS L+ V R RPI+ V E +A P S D L++ N G C+ L V Y + SY+ + +DY ++ D
Sbjct: 50 SLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE-WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANS---YFGFSIDSGKGLVRAEELSFVAGAP--------RANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS----PL----RLCGSP-----DSMFGISLAVLGDLNQDGFPDIAVGAPF--DGDGKVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSG-SLDMDGNQYPDLLVGS-LADTAVLFRARPILHVSHEVSIA------PRSID-LEQPNCAGGHSVCVDLRVCFSY----IAVPSSYSPTVALDYVLDAD 535
BLAST of Alpha-int-3 vs. Ensembl Celegans
Match: ina-1 (Integrin alpha ina-1 [Source:UniProtKB/Swiss-Prot;Acc:Q03600]) HSP 1 Score: 142.51 bits (358), Expect = 5.534e-34 Identity = 244/1077 (22.66%), Postives = 437/1077 (40.58%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPF-DILKDSNETTGALFSCPVTK-----ETQDCKKFVF--------SEHSNES--------------LLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLE-SIKSESQNYEYRNCLTG-AALKSLERKQLVLTAPYSYEGKGLL-------INNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKI-FRNPNVKSIVLGSPGISQYDSTRTQI--KFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTN------NNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSN----GQYGISLENIGDINKD--FIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMIS----PDL-----RGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDM------PFIKTSSSKRLYFENKLNTVTGGGSINCKTP-NSKSNSIINTFN--ILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPG-SCQPILTMQAVL-SLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSP--QRHLRPIVLKIKVKMVANIDLKL--LVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFS--ITTGNKKI-ACNVDILNNITNVIKTRI-----YQDIIPISKLEDVQLKKV-------------TVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
S+N+D+N+P + + + + FG+S+ + LIGAP + + E GA+++C + C++ F ++ NE+ L +V + G CAP +R H Y +GAC+E N Q + C + ++ + ++ EY C+ G +A + + L + G G+ I ++ + N R + Y G+S+ +G+ F + K I + S G ++Y I F Q KL N +++ I G GS +GYS+ +DLN DG D+L+VGAPF + N G V+VY++ + + +H E L+ K L N Q+G+S+ +G+++ D + D AVGAPF DG GAVYIYLG + I+ +K Q+I P+L R +GFS+ G D+D N YPD ++GS V +R+RP+I + ++ + E M D K N C L + IY + ++ +D+ ++ M PF + ++ R + E G S N P S S+ T+ I PV + P++ S+ + P + L DL +YPVL + + + F C +CQ L+++A +P Y+ ++G L +N F S +T + + + +P+N T + L E + +++ + + S + L+ + +V+++ +L++ + PD + + S + EE IG ++ + N+ +V + + I +P+++ G+ LYLL +P + T G ++ C + N + ++ Q+ P ++E ++K+ V N+P + F K D G E + + C + +A C V+C + S + + R+W T IE++ + V I
Sbjct: 19 SFNLDVNAPIYR--YGPSGTNFGYSVAEHFKGDKPV--MLIGAPRGESGQTGTERAGAMYACDINTFYNGGSNHWCEQVRFEYENVEDYAKRPNETRGRTVHPLGKNDQLLASTIVSKGTKNGSALVCAP-LIRYHQTAAYPQGACYELES--NLRLQSTYATCAQKNLPTTDRHNEYGGCMEGFSAAITQDTIVTGLIGAVKWTG-GVFAKKSSANIFDSVVEKYTMNQPNGDMIRTRLVAHDYLGYSVDIGRFGFWYEDGKPITVVS-GATRYGEHGAVIFLPFIQDSSSKLTLNEDKFI--INGTAMGSAFGYSIEVVDLNGDGFDDLIVGAPFEHRSGIDGNFGGIVYVYFSQGVQRK--QH-------ESHLVFHPPKILKNPDFYSQFGLSITKLGNVDGDKSKLNDFAVGAPFAFDGAGAVYIYLGTKN--IEKFRKKPAQVIKGNDLPNLPPGGMRSFGFSLSG-GSDMDENGYPDLLIGSPSKNFVALLRSRPVISIETKHKM-EKRM-----VDIDKGVNCPRGAKTCFPLDMVIY------VDEETKRGAELVDFSSDVFMCNLEAIPF-RADTTARGFIE-------GSHSHNYSWPCGSNSHVQKRTYRQLIYLPVQESKDWITPLKFRFTVSIRNEKKPVQPPQGSQLVDLKHYPVLNKYGASYEFDVPFNTLCGEDHTCQTDLSLKAAFKDIPLTSNGYVSNVGEKDYLDLTFTVENKKEKAYQANFYLEYNEEELELPQVQGSKRMIAETIGKNIVHLPLGNPMNGASKHQFTIQFKLTRGRTEGIGKALKFMAHVNSTSQETEEELKDNKWEAEVQIIKKAELEIYGISDPDRVFFGGKA-RAESELELEEDIGTMVRHNYTIINHGPWTV-RNVEAHISWPYQLRSRFGR--GKNALYLLDVPTITTEFTDGTSEVRKCFIKQQYEYVNPAEIKLNTKYSTQETAP-HRVEH-RMKREIDEDEEEQSDDLGAVEENIPWFSTANFWNLFAIKGGD-GRPRE---VKHLSCQDNTANCFTVICHFDFIDANSA-VVIDLRARLWNATFIEDYSDVESVKI 1041
BLAST of Alpha-int-3 vs. Ensembl Celegans
Match: pat-2 (Integrin alpha pat-2 [Source:UniProtKB/Swiss-Prot;Acc:P34446]) HSP 1 Score: 110.923 bits (276), Expect = 3.587e-24 Identity = 140/552 (25.36%), Postives = 232/552 (42.03%), Query Frame = 3
Query: 168 FFGFSLNIFTSKQNSIKYFLIGAPFDILKDSN----ETTGALFSCPVTKETQDCKK-----------------FVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE--GACWEFNEMFNEVEQISNQDC-LESIKSESQNYEYRNCLTGAALKSLERKQLV-LTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIG----KLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF-----------TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFEN-DGTGAVYIYLGDSHQIIKL-SQKIEGQMISP-DLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPF--IKTSSSKRLYFENK 1688
+FG+SL+ F +Q + ++GAP + N GA+++C V + T C++ V E + G V SN I CAPK+ ++ + +E G C+ F+ E+ S+ C E + Y C AA+ + + V + AP + +G + + N ++ + ++ Y + + G+S A G + + IV G P R G++V+ K++ N + V G+ G SV D+N DG D++++G PF T Q V I M Q T P K++ + + G++G ++ GD+N D D+ VGAP+ + GAVY+ G + +L +QKIEG I +++ +GFS+ G NED+D N PD VG+ SG+ + T+P++ V + E + L D K C+ +G KL + + TC Y ++E D+ F S R YF K
Sbjct: 42 YFGYSLD-FYHEQKGMPVLVVGAPEAESNNPNLAGIRRPGAVYACSVNRAT--CREVHVDKMKGNLKKLNGSHLVPIEEKSHQFFGATVRSNDKHDKIVVCAPKYTYFYSKFEVIEPVGTCFYAENGFDNAEEFSS--CKQEPARHGRHRLGYGQCGFSAAVPGKKNQNRVFIGAPGVWYWQGAMFSQNIKNQTDRPNTEY---GSKEYDHDMMGYSTATGDFDGD-GIDDIVAGVP--------RGNDLHGKLVLYTSKLKMMINLTDEVSTQHGQYCGG----SVAVADVNKDGRDDIIMGCPFYTDYGSVKDAKTQERKPQYDVGKVIVMLQ------TAPGVFGKQIAVVGDDQW--GRFGHAVAAAGDLNLDGYNDVIVGAPYAGKNKQGAVYVIHGSKDGVRELPTQKIEGANIGHGNIKSFGFSLTG-NEDVDGNGMPDIAVGAWKSGNAAVLLTKPVVTVTGQ---TEPESALISVED--KNCDVDG------KLGKQACKH---INTCFKYEGKGDTPNDLEFDLRFNLDDHSPEPRAYFLQK 549
BLAST of Alpha-int-3 vs. Ensembl Fly
Match: mew (gene:FBgn0004456 transcript:FBtr0340190) HSP 1 Score: 202.216 bits (513), Expect = 2.821e-52 Identity = 257/1099 (23.38%), Postives = 456/1099 (41.49%), Query Frame = 3
Query: 63 NFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ----NSIKYFLIGAPFDILKDSNET-TGALFSCPVTKETQDCKKFVFSEHSN----------------ESLLGYVVDSNSHE-----GLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRS-SNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
N L + + +++N++ P +K + + S FG+S+ T + N L+GAP D + N T +GAL+ CP+T+ DC++ + N + +G V SN + G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ + S++ + KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 18 NLGILIILQCVLTCYNFNLEQRLPIVK--YGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 1042
BLAST of Alpha-int-3 vs. Ensembl Fly
Match: mew (gene:FBgn0004456 transcript:FBtr0073732) HSP 1 Score: 201.445 bits (511), Expect = 3.516e-52 Identity = 257/1099 (23.38%), Postives = 456/1099 (41.49%), Query Frame = 3
Query: 63 NFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ----NSIKYFLIGAPFDILKDSNET-TGALFSCPVTKETQDCKKFVFSEHSN----------------ESLLGYVVDSNSHE-----GLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRS-SNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
N L + + +++N++ P +K + + S FG+S+ T + N L+GAP D + N T +GAL+ CP+T+ DC++ + N + +G V SN + G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ + S++ + KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 18 NLGILIILQCVLTCYNFNLEQRLPIVK--YGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 1042
BLAST of Alpha-int-3 vs. Ensembl Fly
Match: mew (gene:FBgn0004456 transcript:FBtr0310647) HSP 1 Score: 197.593 bits (501), Expect = 7.135e-51 Identity = 259/1110 (23.33%), Postives = 458/1110 (41.26%), Query Frame = 3
Query: 63 NFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ----NSIKYFLIGAPFDILKDSNET-TGALFSCPVTKETQDCKKFVFS-------------------------EHSNESLLGYVVDSNSHE-----GLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRSSNYLKFRNSNS---KYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
N L + + +++N++ P +K + + S FG+S+ T + N L+GAP D + N T +GAL+ CP+T+ DC++ + E + +G V SN + G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ +++ Y + NS KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 18 NLGILIILQCVLTCYNFNLEQRLPIVK--YGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRTNGAYEINKHFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRD--KTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 1051
BLAST of Alpha-int-3 vs. Ensembl Fly
Match: mew (gene:FBgn0004456 transcript:FBtr0073731) HSP 1 Score: 171.4 bits (433), Expect = 8.511e-43 Identity = 227/971 (23.38%), Postives = 403/971 (41.50%), Query Frame = 3
Query: 369 VDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRS-SNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
+ +N G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ + S++ + KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 47 LQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 945
BLAST of Alpha-int-3 vs. Ensembl Fly
Match: mew (gene:FBgn0004456 transcript:FBtr0310648) HSP 1 Score: 171.014 bits (432), Expect = 1.108e-42 Identity = 229/973 (23.54%), Postives = 405/973 (41.62%), Query Frame = 3
Query: 369 VDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRSSNYLKFRNSNS---KYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
+ +N G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ +++ Y + NS KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 56 LQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRD--KTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 954
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Match: itga3a (integrin, alpha 3a [Source:ZFIN;Acc:ZDB-GENE-090805-3]) HSP 1 Score: 188.734 bits (478), Expect = 3.953e-48 Identity = 284/1149 (24.72%), Postives = 484/1149 (42.12%), Query Frame = 3
Query: 60 INFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKY-FLIGAPFDILKD--SNETTGALFSCPVTKETQDCKKFVFSEHSNES---LLGYVVDS----------NSHEGLIYTCAPKFLRSHTYVKYVEGACW-EFNEMFNEVEQISNQDCLESIK-SESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYL----KFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENS----LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFG----KNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYF-ENKLNTVTGGGSINCKTPNSKSNSI---INTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT--IHFGVGCS-PGSCQPILTMQAVLS-------LPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTY--IILTYDAKKINLFSNNPD-------RKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSK-------LLIYFPWEISGNPTE-TDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRV---VAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQN 3299
+ +F+ L ++N+D++ +K S FG S+ + N ++ L+GAP + + S TG +++CP++ +++DC + + E L YV+D + G + C +++R+ T + G C+ N++ + Q E E+QN E CL G + ++ ++ AP + +G N +S+ ++ + + K +S Y G+S V + ++V G+P R + K G V++ +++++ ++ + GE GS +G SV +DLNNDG +L+VGAPF + G V+VY N S N + ++LT K + +G+S+ IGD+N+D QD AVGAP+ + TG V I+ G I + SQ I+G+ D+ G GF FG + D+D N YPD VGS L VV +R+RP+I + +N T M + +L+ C + CI+ V Y Y T S + T+ Y +E D ++S S R+ F +N TG S+N P+ +S+ + + I V+ + L+VS V L DLS +PV+ + ++ LT IH C C+ L M A + L E Q + ++ K KL + N+ + + KA Y I+ ++ S NP +S S L+ + P + Q E I + I + + +S Q LRP+ + V+ + L+ P +++G S++ IG ++F I SV +S K L + F W P+ + ++LLYL I TG + C + I N + + + K ++V +S+ + + + G E +++C +G+ARC C PLS L R+W T++E++ + K V + V + L+ N K +I V + VA L P ++ II++V +GV++L IVI+L+KC FF+R N
Sbjct: 9 LRLTLVFVLSAARLCQAFNLDVSFAVVKEGKTAG-SLFGLSVALHEQVVNEKRHMLLVGAPKEKAESGLSANETGDVYACPISADSKDCARLNLISSNPEDKPDLKNYVIDGMWLGVSIVSQSQPGGRVVACGHRYIRNFTSNFRMIGRCYVRGNDLQLNLSDYQWQSYDEICDPREAQNSEGM-CLLGMS-AAVTFSEIFFGAPGCFNWQG-----NIFSKWHNPADEFHLLKSKLPDSRKGNIYIGYSTIVDQDVLVKGKDTVVTGAP--------RDEAK-GSVMMAEVLKSGGSGEVKIKVTVTGEQVGSYFGNSVAVVDLNNDGWKDLIVGAPFYFDRKMDKGGAVYVYMNQNGSFRN----------KSDVVLTGPK---DSGFGMSVVAIGDVNQDGFQDFAVGAPYHS--TGRVSIWTGSKTGISQEPSQVIDGK----DIPGGGFQTFGYSISRGLDVDRNGYPDIAVGS-LDDRVVLLRSRPVIHL--KNTFTVTPMVI-----NLEDC------VACIEAKVCFSYTYS--TGTASSQKAVTLQYTVEADQ---QSSRSPRVSFLDNNKGKYTGKMSVN---PSGDCHSLKLELASKTIQDKVSAII-----------FQLSVSVVDPPPSGGKMLEDLSAFPVISQ-RDALTGRAEIHIQKACGLDNKCESNLQMTAAFTDEKNTPFLMQEDHQIFNYTTDIKKLKLLVNVSNVPS-EGRKAEDAYNAILNITIPSSLSFSSLNPKLPSTLNGDPSSGGSYLLCTLGDPFKSNQ--RVEIEITFETSGISIDMQEIETELQLSTLSDQNDLRPLSRVLLVEYILQPLFNLI--PYFRAEFSGNVVGESAMKSTSDIGSPVEFNI--------SVDISGKPLGNLGFLEVVFQW-----PSAVANEKWLLYLSEIQ----MTGTSESFC---VAKGIVNPLNLTVSERKSRRRKRDEV----------------LSESKLAMSQKTRQGQNKPRE---VLNCTKGTARCQTFSC---PLSAMKTSAMLTVRARVWNSTMLEDY-RAKGVSVQGSVM--------LTLKTDKKNIKMNNNIREFTVEIDPAVAEELPYEAP------LWIIIVSVLSGVVMLGVIVILLWKCGFFKRAN 1025
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Match: itga4 (integrin alpha 4 [Source:ZFIN;Acc:ZDB-GENE-110411-108]) HSP 1 Score: 182.956 bits (463), Expect = 2.666e-47 Identity = 189/682 (27.71%), Postives = 301/682 (44.13%), Query Frame = 3
Query: 72 FLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPF--DILKDSNETTGALFSCPVTKE---------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPK-----FLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYE--YRNCLTGAALKSLERKQLVLTAPYS--YEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIK-LSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFD-SLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSK-----RLYFE-NKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIH----FGVGCSPGSCQPILTMQAVLSLP 2015
F L+++ +L YN+D+ P + + N S FG+S+ + +N+ + L+GAP + ++ GA+++C + Q C + +E+ N+ LG + + +G + C + + K G C+ F+ I + K + + Y +C G + S +V+ AP + + G L++N ++ S+ Y+ + Y G+S++ G F +P IV G+P Q++ T G+ I ++ N+L+ V G+ GS YG SV A+DLN DG+ +L+VGAP + G+V+VY N Q E K E L + ++G ++ N+GDI+ D D+A+GAP E+D GA+YIY G I + SQ+I G ++ + R +G S+ G D+DSN YPD VG+ LS V RTRP+++V A M LP S + S+ +C NGQ CIK+ V K I IEL K R YF N + VT G +K + F+ F +I PI +K+ L V +R+L P+L++ K+ L N I F CS +C L + A L LP
Sbjct: 17 FGILWYLLILCDCYNLDVEHPLVFNG--PNGSLFGYSVLLHQHNENT--WLLVGAPVANSSFYPNIKSPGAIYNCSMLNSQCEQLPVGGVQRCGRHCLAENDNQ-WLGVSLSRQASKGHVLACGHRWKNVFYSSKDNQNKLPHGVCFRFSPDLKHASHI-----IPCYKDHQRRFGEGYGSCQAGIS-NSFTEDLMVMGAPGTSYWTGSVLVVNTT-----SNISAAYVDDDSDVLYGSYLGYSVSAGH-FLDPQSTEIVGGAP---QHEQT------GKAYIFRIEGNTLKIVNKTKGKTLGSYYGASVCAVDLNADGLSDLLVGAPMFSSVREEGRVYVYIN----QGEAELK------EADFELVGSDSYA-ARFGETIINLGDIDDDGYPDVAIGAPQEDDLRGAIYIYNGRRSGIARSFSQRITGSLLGNNFRMFGQSVSG-GVDIDSNNYPDVAVGAFLSDSAVVFRTRPVVKVDAV-------MLLPESLNRSVAQCTENGQPAVCIKVRVCF------------RVRGKQIPGNIELKYNLTADVHHKEGFPSRFYFSGNGTSNVTAG------RVKAKHEQLTCVFHQAFMKKDVRDIFTPIHFEVKYELGEHRVVQRDLGDLPALK----PILQQ-KDELDNVIKNKTIFARYCSWENCSTNLQVSARLVLP 630
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Match: itga4 (integrin alpha 4 [Source:ZFIN;Acc:ZDB-GENE-110411-108]) HSP 1 Score: 183.726 bits (465), Expect = 1.456e-46 Identity = 189/682 (27.71%), Postives = 301/682 (44.13%), Query Frame = 3
Query: 72 FLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPF--DILKDSNETTGALFSCPVTKE---------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPK-----FLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYE--YRNCLTGAALKSLERKQLVLTAPYS--YEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIK-LSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFD-SLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSK-----RLYFE-NKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIH----FGVGCSPGSCQPILTMQAVLSLP 2015
F L+++ +L YN+D+ P + + N S FG+S+ + +N+ + L+GAP + ++ GA+++C + Q C + +E+ N+ LG + + +G + C + + K G C+ F+ I + K + + Y +C G + S +V+ AP + + G L++N ++ S+ Y+ + Y G+S++ G F +P IV G+P Q++ T G+ I ++ N+L+ V G+ GS YG SV A+DLN DG+ +L+VGAP + G+V+VY N Q E K E L + ++G ++ N+GDI+ D D+A+GAP E+D GA+YIY G I + SQ+I G ++ + R +G S+ G D+DSN YPD VG+ LS V RTRP+++V A M LP S + S+ +C NGQ CIK+ V K I IEL K R YF N + VT G +K + F+ F +I PI +K+ L V +R+L P+L++ K+ L N I F CS +C L + A L LP
Sbjct: 17 FGILWYLLILCDCYNLDVEHPLVFNG--PNGSLFGYSVLLHQHNENT--WLLVGAPVANSSFYPNIKSPGAIYNCSMLNSQCEQLPVGGVQRCGRHCLAENDNQ-WLGVSLSRQASKGHVLACGHRWKNVFYSSKDNQNKLPHGVCFRFSPDLKHASHI-----IPCYKDHQRRFGEGYGSCQAGIS-NSFTEDLMVMGAPGTSYWTGSVLVVNTT-----SNISAAYVDDDSDVLYGSYLGYSVSAGH-FLDPQSTEIVGGAP---QHEQT------GKAYIFRIEGNTLKIVNKTKGKTLGSYYGASVCAVDLNADGLSDLLVGAPMFSSVREEGRVYVYIN----QGEAELK------EADFELVGSDSYA-ARFGETIINLGDIDDDGYPDVAIGAPQEDDLRGAIYIYNGRRSGIARSFSQRITGSLLGNNFRMFGQSVSG-GVDIDSNNYPDVAVGAFLSDSAVVFRTRPVVKVDAV-------MLLPESLNRSVAQCTENGQPAVCIKVRVCF------------RVRGKQIPGNIELKYNLTADVHHKEGFPSRFYFSGNGTSNVTAG------RVKAKHEQLTCVFHQAFMKKDVRDIFTPIHFEVKYELGEHRVVQRDLGDLPALK----PILQQ-KDELDNVIKNKTIFARYCSWENCSTNLQVSARLVLP 630
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Match: itga4 (integrin alpha 4 [Source:ZFIN;Acc:ZDB-GENE-110411-108]) HSP 1 Score: 183.726 bits (465), Expect = 1.456e-46 Identity = 189/682 (27.71%), Postives = 301/682 (44.13%), Query Frame = 3
Query: 72 FLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPF--DILKDSNETTGALFSCPVTKE---------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPK-----FLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYE--YRNCLTGAALKSLERKQLVLTAPYS--YEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIK-LSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFD-SLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSK-----RLYFE-NKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIH----FGVGCSPGSCQPILTMQAVLSLP 2015
F L+++ +L YN+D+ P + + N S FG+S+ + +N+ + L+GAP + ++ GA+++C + Q C + +E+ N+ LG + + +G + C + + K G C+ F+ I + K + + Y +C G + S +V+ AP + + G L++N ++ S+ Y+ + Y G+S++ G F +P IV G+P Q++ T G+ I ++ N+L+ V G+ GS YG SV A+DLN DG+ +L+VGAP + G+V+VY N Q E K E L + ++G ++ N+GDI+ D D+A+GAP E+D GA+YIY G I + SQ+I G ++ + R +G S+ G D+DSN YPD VG+ LS V RTRP+++V A M LP S + S+ +C NGQ CIK+ V K I IEL K R YF N + VT G +K + F+ F +I PI +K+ L V +R+L P+L++ K+ L N I F CS +C L + A L LP
Sbjct: 17 FGILWYLLILCDCYNLDVEHPLVFNG--PNGSLFGYSVLLHQHNENT--WLLVGAPVANSSFYPNIKSPGAIYNCSMLNSQCEQLPVGGVQRCGRHCLAENDNQ-WLGVSLSRQASKGHVLACGHRWKNVFYSSKDNQNKLPHGVCFRFSPDLKHASHI-----IPCYKDHQRRFGEGYGSCQAGIS-NSFTEDLMVMGAPGTSYWTGSVLVVNTT-----SNISAAYVDDDSDVLYGSYLGYSVSAGH-FLDPQSTEIVGGAP---QHEQT------GKAYIFRIEGNTLKIVNKTKGKTLGSYYGASVCAVDLNADGLSDLLVGAPMFSSVREEGRVYVYIN----QGEAELK------EADFELVGSDSYA-ARFGETIINLGDIDDDGYPDVAIGAPQEDDLRGAIYIYNGRRSGIARSFSQRITGSLLGNNFRMFGQSVSG-GVDIDSNNYPDVAVGAFLSDSAVVFRTRPVVKVDAV-------MLLPESLNRSVAQCTENGQPAVCIKVRVCF------------RVRGKQIPGNIELKYNLTADVHHKEGFPSRFYFSGNGTSNVTAG------RVKAKHEQLTCVFHQAFMKKDVRDIFTPIHFEVKYELGEHRVVQRDLGDLPALK----PILQQ-KDELDNVIKNKTIFARYCSWENCSTNLQVSARLVLP 630
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Match: itga6a (integrin, alpha 6a [Source:ZFIN;Acc:ZDB-GENE-050309-23]) HSP 1 Score: 169.859 bits (429), Expect = 3.533e-42 Identity = 276/1150 (24.00%), Postives = 469/1150 (40.78%), Query Frame = 3
Query: 69 IFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKY-FLIGAP--FDILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLR-----SHTYVKYVEGACWEFNEMFNEVEQISNQDC--LESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL--------------LINNNFY--SRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNN--NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTID---YEIELDMP----FIKTSSSKRLYFENKLNTVTGGGSINC-KTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNN--LTNTIHFGVGCSPGS-CQPILTMQAVLS-----------LPTEGEQYILHMGNVSKFKLEIQTKN-----------IATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQN-SVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGN-YKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
+ +F + V ++N+D + KS S FGFS+ + Q K LIGAP + TG L+SC +T DC + F E+ +G V S G I TCA ++ R + + + G C+ ++ + ++ S++D + ++ +E + C G AA + + ++ AP +Y KG+ L ++ Y EN N + +NS Y GFS+ G IV G+P + + K G++ E+ LE G S +GY V +DLN DG ++VVGAP F + G V+VY N ++ P+ + + +G+S+ENIGD+N D +D+AVGAP+ + G G+VYIY G + I K +Q +EG+ + + +G+S+ G N DLD N+YPD VGS LS V R++ +I + + V P D KK N C+ + Y T P S T + Y +L +P F+ + + Y + G C KT + I + ++PIE+++ ++ ++ KR L P+L+ N LT GC + CQ L +Q LP E ++ + + LE+ +N ++ DD+ ++ + L + K + +N G + +S + TF +L I + + I++ +E S Q L + K KV + + ++ + P Y + G S++ EE++G +++ + N + ++ L I +P E S G++LLYL++I T + + C+ + N +K R I +LE+ + P+ K+ +D+ K ++ C G ARCV + C PL + R+W T +E+F Y Y+DI +V + L V N K P+ +VR+ P + + I++AV AG+++LA +V++L+KC FF+R
Sbjct: 12 LCVFSWLVWTSASAFNLDTQNVLRKSG--QPGSLFGFSIALHRQLQPHDKTILLIGAPKARALSNQGANVTGGLYSCDITTHPNDCSRVDFDNDVDVRVENKENQWMGVTVQSQGPGGKIVTCAHRYQRLLFPNTPQEARDITGRCYMLSQDLS-IDNQSDEDGGNWKFCDGRTRGHERFGACQQGLAATFTKDYHYVIFGAPGAYNWKGIVRIEQKNNTLLEMGLFDDGPYEVGDENRLDPNLVPV-PANS---YLGFSLDSGHSITEKGKLIIVSGAPRANHSGAVVFLRKEGELSSMLTPEHILE------GPGLASSFGYDVAVVDLNGDGWQDVVVGAPQFFQRDEEVGGAVYVYIN----KAGRWRDVTPV---------RLNGTKDSMFGLSVENIGDVNLDSFEDIAVGAPYADSGFGSVYIYHGSADGISTKPAQILEGKQHNTKM--FGYSLAG-NMDLDHNSYPDLAVGS-LSDTVFIYRSKNVISIKKDIKVT------PKEIDLTKKTCGNS---ICLTVEACFSYRANPTTYNPKITISCTFEAEWYRRKLGLPSRVVFLDKTEIDQDYQSTGTLELRGQNKKACYKTKLRLQDGIRDKLR-----------AIPIEVSV--AIQSAKRGKRQSSLPQLV-----PILDSTVPNKTLTEVNFLKEGCGTDNICQSNLNLQYRFCYRESKQDIFPPLPLENGVPVISLSDQKDIALEVTVRNRNGDDAHEAKLVSHFDDSLSYSGFRSLRTNDKHVICAANQNGSLADCELGNPFKRDSEV--------TFYIILSTGKISLETKEVEIDLQLETTSSQEGLSKVKAKAKVVIELLLSVQGVAKPSQV-YFGGEVKGMSAMKKEEEVGSLIEYEFRVINLGKPLKSFGTASLNIQWPKESSV------GKWLLYLMKIN----TRDLQLVTCSPE---REINPLKLREDSSIRKKRELEERR------PSEGNKISLFTDKRKH----------------KILSC-SGDARCVEIKC---PLQGLDSTAVIVLKSRLWNSTFLEDFASYN--YLDI------IVKASISLDVSAKNIVLKNPET---QVRLTVFPETTATPFGGVP-WWIILVAVLAGILMLALLVLLLWKCGFFKR 1044
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Match: ITGA3 (integrin subunit alpha 3 [Source:NCBI gene;Acc:100494331]) HSP 1 Score: 175.637 bits (444), Expect = 6.018e-44 Identity = 268/1102 (24.32%), Postives = 468/1102 (42.47%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFSEHSNES-------LLGYVVDSNSHEGLIYTCAPKFL----------RSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNN----NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTN-TIHFGVGC-SPGSCQPILTMQ---AVLSLPTEGEQYILHM-GNVSKFKLEIQTKNI--ATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNAT--FECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQ-YREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTE-TDGQYLLYLLRIPKFSITTGNKKIACNV--DILNNIT-NVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
++N+D P +K + FGFS+++ + +Y L+ GAP D S + TGAL++CP+T T DC + S+ LG V S +G + C ++ R Y+ G E NE ++ + N+ C + ++ C G + + AP +Y +G +N R+ + + + +N+ Y G+++ V + + ++V +P R + K G V + + +N + V+ G+ GS +G ++ DLNNDG ++VVGAP+ + G V+VY N+ + +K ++ S +G +L NIGDIN+D DLAVGAPF DG G VYIY ++ + SQ I+G ++ ++ +G+S+ G D+D N YPD +VGS L+ + +R+RP+I + D ++ + KC++ CI + V Y T +Y + T+ Y +E D R+ F+ V G P++K ++ +L N+ + PI I++K+S+ E R+ + N+PVL ++N IHF C S C+ L MQ V + P ILH +V+K L + N AT+ + A + +T ++ S P + +I + P Q T FE + I + + + +S Q L K+ V I V P + Q Y +++G S++ + +G ++F+ + N + L++ L I F W P E +G++LLY + + TG +K AC+ D++N + NV +T + + I + DV+ ++ + ++ C G A CV C PL+ T+ R+W T +E++ V++ + + + VP N K V+ V + + L++P PPA L ++ II++V +G++LL I+++L+K FF R
Sbjct: 24 AFNLDTRFPVLKEAGVPG-GLFGFSVSLHRQSEGEQRYLLLSGAPQDAAAPSVKANRTGALYACPITSSTNDCFRVPIDPESDPQNNIIENMWLGVTVASQGPDGRVLVCGHRYTSVRWSGEEDQRRMIGKCYIRGNNLELNED-DDWQTYHNELCDPNSDFDATGM----CQMGIS-GGFTSNMVYFGAPGAYTWQG---SNFILQRDTAWDLKEIYYPTNNTFNIYMGYTVQVNSRVLHKDQVTVVSSAP--------RWESK-GAVFLLDVQKNIMVVKHVLNGQQVGSYFGSAIALADLNNDGWQDIVVGAPYYFDRKEEIGGAVYVYNNVAGFFN-----------DKAAMVLHGSSFSG--FGFALANIGDINQDGFTDLAVGAPF--DGLGKVYIYNSNADGPKQEPSQVIDGSQVA-NISTFGYSLSG-GLDVDDNAYPDLLVGS-LTDRIALLRSRPVINI-------SKDFKVTPTLVDPSKCSNTS----CIDVLVCFSYTLS--TGNAAYRKNITLQYTLEAD----HDRRPPRVKFQGASGAVYQG---LFSMPDTKCQNV----QLLLLDNIRDKLH-PISISLKYSILEREARGRSAVRSLD----NFPVLSEDQSNFQELEIHFQKECGSDNVCRSNLQMQYEYVVGNAPLVNGSQILHYDSSVNKVNLNVIVTNFPSATSPADDAHEAVLNITI-PPELFFSSVRPPLACTLKETIICELGFPFKRNQKAEITIVFEVV----GISLKTREVVAGLQLSTLSKQDDLHEEYAKLLVDYTLKISFS--VQPSHIQTYFSGNVMGESAMKTVQDVGSPVEFSFTVINYGEPLTSLAT-LFIAFNW-----PHEVANGKWLLYPTEV---LVNTGTEK-ACHPSGDVINPLNLNVSETLVKRRRRQIDETPDVRTL---------------------------AAVRRESSEAVLKCSGGGATCVHFSC---PLNDMQSRATISMRGRVWNSTFLEDYRNVDRVWV------MGGAELYLKTDVPTINMKS--QFVTFSVSI-DSELEEP-PPAELP-LWLIIVSVVSGIVLLGIIILLLWKIGFFHR 1001
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Match: ITGA3 (integrin subunit alpha 3 [Source:NCBI gene;Acc:100494331]) HSP 1 Score: 171.014 bits (432), Expect = 1.849e-42 Identity = 265/1104 (24.00%), Postives = 466/1104 (42.21%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVK----------------YVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNN----NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNN---LTNTIHFGVGC-SPGSCQPILTMQ---AVLSLP---TEGEQYILHMGNVSKFKLEIQTKNI--ATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQ-YREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTE-TDGQYLLYLLRIPKFSITTGNKKIACNV--DILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQN 3299
++N+D P +K + FGFS+++ + +Y L+ GAP D S + TGAL++CP+T T DC + S + H L + C P + H Y Y+ G E NE ++ + N+ C + ++ C G + + AP +Y +G +N R+ + + + +N+ Y G+++ V + + ++V +P +++S G V + + +N + V+ G+ GS +G ++ DLNNDG ++VVGAP+ + G V+VY N+ + +K ++ S +G +L NIGDIN+D DLAVGAPF DG G VYIY ++ + SQ I+G ++ ++ +G+S+ G D+D N YPD +VGS L+ + +R+RP+I + D ++ + KC++ CI + V Y T +Y + T+ Y +E D R+ F+ V G P++K ++ +L N+ + PI I++K+S+ E R+ + L N+PVL ++N L +IHF C S C+ L MQ V + P G Q + + +V+K L + N AT+ + A + +T + LF ++ ++TS I V FE + I + + + +S Q L K+ V I V P + Q Y +++G S++ + +G ++F+ + N + L++ L I F W P E +G++LLY + + TG +K AC+ D++N + + +S L + +++ +I P ++ + ++ C G A CV C PL+ T+ R+W T FL+ K + + + L + V + + L++P PPA L ++ II++V +G++LL I+++L+KC FFRR N
Sbjct: 21 AFNLDTRFPVLKEAGVPG-GLFGFSVSLHRQSEGEQRYLLLSGAPQDAAAPSVKANRTGALYACPITSSTNDCFRVPIDPESK--------CKDPHGTLQFLCHPCQVCGHRYTSVRWSGEEDQRRMIGKCYIRGNNLELNED-DDWQTYHNELCDPNSDFDATGM----CQMGIS-GGFTSNMVYFGAPGAYTWQG---SNFILQRDTAWDLKEIYYPTNNTFNIYMGYTVQVNSRVLHKDQVTVVSSAP---RWESK------GAVFLLDVQKNIMVVKHVLNGQQVGSYFGSAIALADLNNDGWQDIVVGAPYYFDRKEEIGGAVYVYNNVAGFFN-----------DKAAMVLHGSSFSG--FGFALANIGDINQDGFTDLAVGAPF--DGLGKVYIYNSNADGPKQEPSQVIDGSQVA-NISTFGYSLSG-GLDVDDNAYPDLLVGS-LTDRIALLRSRPVINI-------SKDFKVTPTLVDPSKCSNTS----CIDVLVCFSYTLS--TGNAAYRKNITLQYTLEAD----HDRRPPRVKFQGASGAVYQG---LFSMPDTKCQNV----QLLLLDNIRDKLH-PISISLKYSILEREARGRS----AVRSLDNFPVLSEDQSNFQELEVSIHFQKECGSDNVCRSNLQMQYEYVVGNAPLSKVNGSQILHYDSSVNKVNLNVIVTNFPSATSPADDAHEAVLNITIPPE---LFFSSVRPVSATSPAEITIV-------------FEVV----GISLKTREVVAGLQLSTLSKQDDLHEEYAKLLVDYTLKISFS--VQPSHIQTYFSGNVMGESAMKTVQDVGSPVEFSFTVINYGEPLTSLAT-LFIAFNW-----PHEVANGKWLLYPTEV---LVNTGTEK-ACHPSGDVINPLN-----------LNVSVLFSIFIQR-------------RRQIDETPDVRTLAAVRRESSEAVLKCSGGGATCVHFSC---PLNDMQSRATISMRGRVWNST----FLEVKKILNPVTIQPAALAIFSVSID---------------------SELEEP-PPAELP-LWLIIVSVVSGIVLLGIIILLLWKCGFFRRAN 964
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Match: ITGA4 (integrin subunit alpha 4 [Source:NCBI gene;Acc:100487924]) HSP 1 Score: 169.474 bits (428), Expect = 3.934e-42 Identity = 190/710 (26.76%), Postives = 310/710 (43.66%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETT-GALFSCPVTKE--------------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYV---KYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNY--EYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKN----EDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLK-KCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYF--ENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVK---NNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYI-LHMGNVSKFKLEIQTKNIATTDDNKAFRTYIIL 2135
SYNID +SP + + S FGFS+ + ++ + + ++GAP N T GA+ C + + C K E N+ L + ++ +G I C ++ H + K G C+ F ++S + C K + + Y +C G + +E +V+ AP S+ G + N + EN+ S Y+ N+ Y G+S+ G FR PN ++ G+P Q + G+ I E L + G+ GS +G +V A+DLN DG+ +L+VGAP T G+VFVY N +E+ S L ++G ++ N+GDI+ D +D+A+ AP E D GAVYIY G I SQ+++G GYG +FG++ D+D N Y D +G+ LS V +RTRP+I V + ++LP + + + +C NG P + ++V+I + Y L P Y + Y I D+ K+ + R YF + ++G +I+ K+ N K++ F +I PI + + L V KR+ PVL++ + N +TN +HF C+ +C L + LS P E + L +G + + I N + AF+T + L
Sbjct: 32 SYNIDESSPVVFKG--SQGSLFGFSVVLHSNGDGN--WIVVGAPQSSWTTKNVTNPGAILKCRIEQNPNGSCDVLELGNLNGAKCGKTCKEEQDNQWLGVSLSRQSTKDGQILACGHRWKNIHFMLSDHKLPYGVCYGIPANFRT--ELSKRIC-PCYKDHVRKFGDSYGSCQAGISTFYVE-DVIVMGAPGSFYWTGSIFVYN--TTENTIKS-YVDLNNAVKFGSYLGYSVGAGH-FRTPNSYEVIGGAP---------QQEQTGKAYIFTYEEKQLVILFEAGGKKLGSYFGAAVCAVDLNGDGLSDLLVGAPMQSTIREEGRVFVYMNTGGGA-----------MEELQFELSGSDLYAARFGDTIANLGDIDNDGFEDVAIAAPQEGDLEGAVYIYNGREKGITPSFSQRLQGSKF-----GYGLRMFGQSISNVLDIDGNGYNDVAIGAFLSDSAVLLRTRPVI-------VIDASLKLPMTVNKTRFECMENG--APAVCMNVTICFAYKGLDV-PGYI---VMYYNITSDVR-RKSGTPARFYFVSNGTSDVMSGTMNIHQKSGNCKTHKA-------FMRKDTRDIFTPIHMESSYYLGKHIVSKRSADDLQPLQ----PVLQQKEGKGNVITNKVHFARHCTLLNCSADLQITGKLSFPKPFESKLYLAVGGMKSLMINITLFN----GGDDAFQTVLQL 675
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Match: ITGA4 (integrin subunit alpha 4 [Source:NCBI gene;Acc:100487924]) HSP 1 Score: 169.859 bits (429), Expect = 4.115e-42 Identity = 193/710 (27.18%), Postives = 312/710 (43.94%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETT-GALFSCPVTKE--------------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYV---KYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNY--EYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKN----EDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLK-KCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYF--ENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVK---NNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYI-LHMGNVSKFKLEIQTKNIATTDDNKAFRTYIIL 2135
SYNID +SP + + S FGFS+ + ++ + + ++GAP N T GA+ C + + C K E N+ L + ++ +G I C ++ H + K G C+ F ++S + C K + + Y +C G + +E +V+ AP S+ G + N + EN+ S Y+ N+ Y G+S+ G FR PN ++ G+P Q + G+ I E L + G+ GS +G +V A+DLN DG+ +L+VGAP T G+VFVY N T +E+ S L ++G ++ N+GDI+ D +D+A+ AP E D GAVYIY G I SQ+++G GYG +FG++ D+D N Y D +G+ LS V +RTRP+I V + ++LP + + + +C NG P + ++V+I + Y L P Y + Y I D+ K+ + R YF + ++G +I+ K+ N K++ F +I PI + + L V KR+ PVL++ + N +TN +HF C+ +C L + LS P E + L +G + + I N DD AF+T + L
Sbjct: 32 SYNIDESSPVVFKG--SQGSLFGFSVVLHSNGDGN--WIVVGAPQSSWTTKNVTNPGAILKCRIEQNPNGSCDVLELGNLNGAKCGKTCKEEQDNQWLGVSLSRQSTKDGQILACGHRWKNIHFMLSDHKLPYGVCYGIPANFRT--ELSKRIC-PCYKDHVRKFGDSYGSCQAGISTFYVE-DVIVMGAPGSFYWTGSIFVYN--TTENTIKS-YVDLNNAVKFGSYLGYSVGAGH-FRTPNSYEVIGGAP---------QQEQTGKAYIFTYEEKQLVILFEAGGKKLGSYFGAAVCAVDLNGDGLSDLLVGAPMQSTIREEGRVFVYMN-----------TGGGAMEELQFELSGSDLYAARFGDTIANLGDIDNDGFEDVAIAAPQEGDLEGAVYIYNGREKGITPSFSQRLQGSKF-----GYGLRMFGQSISNVLDIDGNGYNDVAIGAFLSDSAVLLRTRPVI-------VIDASLKLPMTVNKTRFECMENG--APAVCMNVTICFAYKGLDV-PGYI---VMYYNITSDVR-RKSGTPARFYFVSNGTSDVMSGTMNIHQKSGNCKTHKA-------FMRKDTRDIFTPIHMESSYYLGKHIVSKRSADDLQPLQ----PVLQQKEGKGNVITNKVHFARHCTLLNCSADLQITGKLSFPKPFESKLYLAVGGMKSLMINITLFN--GGDD--AFQTVLQL 675
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Match: ITGA4 (integrin subunit alpha 4 [Source:NCBI gene;Acc:100487924]) HSP 1 Score: 169.474 bits (428), Expect = 4.202e-42 Identity = 193/710 (27.18%), Postives = 312/710 (43.94%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETT-GALFSCPVTKE--------------TQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYV---KYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNY--EYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKN----EDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLK-KCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYF--ENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVK---NNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYI-LHMGNVSKFKLEIQTKNIATTDDNKAFRTYIIL 2135
SYNID +SP + + S FGFS+ + ++ + + ++GAP N T GA+ C + + C K E N+ L + ++ +G I C ++ H + K G C+ F ++S + C K + + Y +C G + +E +V+ AP S+ G + N + EN+ S Y+ N+ Y G+S+ G FR PN ++ G+P Q + G+ I E L + G+ GS +G +V A+DLN DG+ +L+VGAP T G+VFVY N T +E+ S L ++G ++ N+GDI+ D +D+A+ AP E D GAVYIY G I SQ+++G GYG +FG++ D+D N Y D +G+ LS V +RTRP+I V + ++LP + + + +C NG P + ++V+I + Y L P Y + Y I D+ K+ + R YF + ++G +I+ K+ N K++ F +I PI + + L V KR+ PVL++ + N +TN +HF C+ +C L + LS P E + L +G + + I N DD AF+T + L
Sbjct: 32 SYNIDESSPVVFKG--SQGSLFGFSVVLHSNGDGN--WIVVGAPQSSWTTKNVTNPGAILKCRIEQNPNGSCDVLELGNLNGAKCGKTCKEEQDNQWLGVSLSRQSTKDGQILACGHRWKNIHFMLSDHKLPYGVCYGIPANFRT--ELSKRIC-PCYKDHVRKFGDSYGSCQAGISTFYVE-DVIVMGAPGSFYWTGSIFVYN--TTENTIKS-YVDLNNAVKFGSYLGYSVGAGH-FRTPNSYEVIGGAP---------QQEQTGKAYIFTYEEKQLVILFEAGGKKLGSYFGAAVCAVDLNGDGLSDLLVGAPMQSTIREEGRVFVYMN-----------TGGGAMEELQFELSGSDLYAARFGDTIANLGDIDNDGFEDVAIAAPQEGDLEGAVYIYNGREKGITPSFSQRLQGSKF-----GYGLRMFGQSISNVLDIDGNGYNDVAIGAFLSDSAVLLRTRPVI-------VIDASLKLPMTVNKTRFECMENG--APAVCMNVTICFAYKGLDV-PGYI---VMYYNITSDVR-RKSGTPARFYFVSNGTSDVMSGTMNIHQKSGNCKTHKA-------FMRKDTRDIFTPIHMESSYYLGKHIVSKRSADDLQPLQ----PVLQQKEGKGNVITNKVHFARHCTLLNCSADLQITGKLSFPKPFESKLYLAVGGMKSLMINITLFN--GGDD--AFQTVLQL 675
BLAST of Alpha-int-3 vs. Ensembl Mouse
Match: Itga3 (integrin alpha 3 [Source:MGI Symbol;Acc:MGI:96602]) HSP 1 Score: 208.379 bits (529), Expect = 2.631e-54 Identity = 252/1041 (24.21%), Postives = 435/1041 (41.79%), Query Frame = 3
Query: 105 FSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDIL--KDSNETTGALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVE------QISNQDCLESIKSE--SQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ-YTGFSMAVGKIFRNP-NVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIE-------LDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYIN----------------ISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID 3050
F++N+D +K +N S FG+S+ + + +Y L+ GAP D+ D TGA++ CP+T DC++ SE S+ + LG V S G + CA H Y K + + M + Q+ D ++ +E + N +Y C G + + + AP +Y KG N+ R++ S Y +R S + Y G+++ VG +P ++ ++V G+P R Q ++ + L+ V+ G G+ +G ++ DLNNDG +L+VGAP+ G V+V+ M+Q+ P LLL S +GIS+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ GK D+D N YPD +VGS LS H+V +R RP+I + +VA P D C + C++ V + + Y P+Y + T+ Y +E + F ++ SS F + T +C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T +HF C P + C L M+A LS + + + + K L I N ++ +LT + S L+ + P Q++N T C L N F N + + I + + S Q +L+P++L ++V L L+ N++ + +++G +++ E +G +K+ + L + +L + +P+E+ T+G++LLY I S N C N+ N + + ++ L + ++ P P ++ + + ++ ++ C G ARCV + C PL S + R+W T IE++ + V +D
Sbjct: 31 FAFNLDTRFLVVKEA-VNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCA------HRYTKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEY-SYRGSEEQGNLYIGYTVQVGNAILHPTDIITVVTGAP--------RHQHMGAVFLLKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVF----MNQAGASFPDQP-----SLLLHGP---SRSAFGISIASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSGGLLRQPQQIIHGEKLGLPGLATFGYSLSGK-MDVDENLYPDLLVGS-LSDHIVLLRARPVINILHRTLVAR-----PAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFARSQSSVFHGFFSMPET-------HCQT--LELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDA-------------YPVLNQAQAMENHTEVHFQKECGPDNKCDSNLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGEDAHEALLTLE----------------VPSALLLSSVRPSGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQLSTSSHQDNLQPVLLTLQVDYTLQASLSLM----NHRLQSFFGGTVMGEAAMKTAEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEV------TNGKWLLYPTEITIHS----NGSWPCQPS--GNLVNPLNLTLSDP--GVTPLSPQRRRRQLDPGGDQSSPPVT-----------LAAAKKAKSETVLTCSNGRARCVWLEC---PLPDTSNITNVTVKARVWNSTFIEDYKDFDRVRVD 953
BLAST of Alpha-int-3 vs. Ensembl Mouse
Match: Itga3 (integrin alpha 3 [Source:MGI Symbol;Acc:MGI:96602]) HSP 1 Score: 207.994 bits (528), Expect = 3.713e-54 Identity = 252/1041 (24.21%), Postives = 435/1041 (41.79%), Query Frame = 3
Query: 105 FSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDIL--KDSNETTGALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVE------QISNQDCLESIKSE--SQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ-YTGFSMAVGKIFRNP-NVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIE-------LDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYIN----------------ISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID 3050
F++N+D +K +N S FG+S+ + + +Y L+ GAP D+ D TGA++ CP+T DC++ SE S+ + LG V S G + CA H Y K + + M + Q+ D ++ +E + N +Y C G + + + AP +Y KG N+ R++ S Y +R S + Y G+++ VG +P ++ ++V G+P R Q ++ + L+ V+ G G+ +G ++ DLNNDG +L+VGAP+ G V+V+ M+Q+ P LLL S +GIS+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ GK D+D N YPD +VGS LS H+V +R RP+I + +VA P D C + C++ V + + Y P+Y + T+ Y +E + F ++ SS F + T +C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T +HF C P + C L M+A LS + + + + K L I N ++ +LT + S L+ + P Q++N T C L N F N + + I + + S Q +L+P++L ++V L L+ N++ + +++G +++ E +G +K+ + L + +L + +P+E+ T+G++LLY I S N C N+ N + + ++ L + ++ P P ++ + + ++ ++ C G ARCV + C PL S + R+W T IE++ + V +D
Sbjct: 31 FAFNLDTRFLVVKEA-VNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCA------HRYTKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEY-SYRGSEEQGNLYIGYTVQVGNAILHPTDIITVVTGAP--------RHQHMGAVFLLKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVF----MNQAGASFPDQP-----SLLLHGP---SRSAFGISIASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSGGLLRQPQQIIHGEKLGLPGLATFGYSLSGK-MDVDENLYPDLLVGS-LSDHIVLLRARPVINILHRTLVAR-----PAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFARSQSSVFHGFFSMPET-------HCQT--LELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDA-------------YPVLNQAQAMENHTEVHFQKECGPDNKCDSNLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGEDAHEALLTLE----------------VPSALLLSSVRPSGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQLSTSSHQDNLQPVLLTLQVDYTLQASLSLM----NHRLQSFFGGTVMGEAAMKTAEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEV------TNGKWLLYPTEITIHS----NGSWPCQPS--GNLVNPLNLTLSDP--GVTPLSPQRRRRQLDPGGDQSSPPVT-----------LAAAKKAKSETVLTCSNGRARCVWLEC---PLPDTSNITNVTVKARVWNSTFIEDYKDFDRVRVD 953
BLAST of Alpha-int-3 vs. Ensembl Mouse
Match: Itga3 (integrin alpha 3 [Source:MGI Symbol;Acc:MGI:96602]) HSP 1 Score: 194.126 bits (492), Expect = 7.821e-50 Identity = 243/1005 (24.18%), Postives = 415/1005 (41.29%), Query Frame = 3
Query: 210 SIKYFLIGAPFDIL--KDSNETTGALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVE------QISNQDCLESIKSE--SQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ-YTGFSMAVGKIFRNP-NVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIEL-------DMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYIN----------------ISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID 3050
S L GAP D+ D TGA++ CP+T DC++ SE S+ + LG V S G + CA H Y K + + M + Q+ D ++ +E + N +Y C G + + + AP +Y KG N+ R++ S Y +R S + Y G+++ VG +P ++ ++V G+P R Q ++ + L+ V+ G G+ +G ++ DLNNDG +L+VGAP+ G V+V+ M+Q+ P LLL S +GIS+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ GK D+D N YPD +VGS LS H+V +R RP+I + +VA P D C + C++ V + + Y P+Y + T+ Y +E + F ++ SS F + T +C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T +HF C P + C L M+A LS + + + + K L I N ++ +LT + S L+ + P Q++N T C L N F N + + I + + S Q +L+P++L ++V L L+ N++ + +++G +++ E +G +K+ + L + +L + +P+E+ T+G++LLY I S N C N+ N + + ++ L + ++ P P ++ + + ++ ++ C G ARCV + C PL S + R+W T IE++ + V +D
Sbjct: 35 SFSSLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCA------HRYTKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEY-SYRGSEEQGNLYIGYTVQVGNAILHPTDIITVVTGAP--------RHQHMGAVFLLKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVF----MNQAGASFPDQP-----SLLLHGP---SRSAFGISIASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSGGLLRQPQQIIHGEKLGLPGLATFGYSLSGK-MDVDENLYPDLLVGS-LSDHIVLLRARPVINILHRTLVAR-----PAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFARSQSSVFHGFFSMPET-------HCQT--LELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDA-------------YPVLNQAQAMENHTEVHFQKECGPDNKCDSNLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGEDAHEALLTLEVP----------------SALLLSSVRPSGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQLSTSSHQDNLQPVLLTLQVDYTLQASLSLM----NHRLQSFFGGTVMGEAAMKTAEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEV------TNGKWLLYPTEITIHS----NGSWPCQPS--GNLVNPLNLTLSDP--GVTPLSPQRRRRQLDPGGDQSSPPVT-----------LAAAKKAKSETVLTCSNGRARCVWLEC---PLPDTSNITNVTVKARVWNSTFIEDYKDFDRVRVD 922
BLAST of Alpha-int-3 vs. Ensembl Mouse
Match: Itga4 (integrin alpha 4 [Source:MGI Symbol;Acc:MGI:96603]) HSP 1 Score: 169.859 bits (429), Expect = 2.873e-42 Identity = 193/703 (27.45%), Postives = 306/703 (43.53%), Query Frame = 3
Query: 69 IFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFD--ILKDSNETTGALFSCPVTK--------------ETQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPK-----FLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQL-VLTAPYSYEGKGLL----INNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLK-KCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNN--LTNTIHFGVGCSPGSCQPILTMQAVLSL--PTEGEQYILHMGNVSKFKLEI 2075
+ L F VP + SYN+D + + + + FG+S+ + + S ++ ++GAP + S GA++ C + K + C K E N+ L + G I TC + +++S K G C+ M +++ ++ K ++ + A + S + L V+ AP S G + I N Y R N +KF + Y G+S+ G FR+P+ +V G+P Q G+ I + EN L V + G+ GS +G SV A+DLN DG +L+VGAP T G+VFVY N M +E + R+L+ S K + ++G S+ N+GDI+ D +D+A+GAP E+D GAVYIY G I SQ+IEGQ IS LR +G SI G+ D D+N Y D VG+ S V +RTRP++ + E + P S + K C NG C+ L++ Y ++ P Y + Y + LD+ S S+ +F N + V GSI + K + + F +I PI + + L + KRN P+L++ K + I+F C+ +C L + A + P E + Y L +G++ L +
Sbjct: 21 MLLLYFGVPTGH-SYNLDPENALLYQG--PSGTLFGYSVVLHS--HGSKRWLIVGAPTASWLSNASVVNPGAIYRCGIRKNPNQTCEQLQLGSPSGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYMKSDN--KLPTGICYV---MPSDLRTELSKRMAPCYKDYTRKFGENFASCQAGISSFYTQDLIVMGAPGSSYWTGTVFVYNITTNQYKAFVDRQ-NQVKFGS------YLGYSVGAGH-FRSPHTTEVVGGAPQHEQ---------IGKAYIFSIDENELNIVYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGMGAVMVEME--------RVLVGSDKYAA--RFGESIANLGDIDNDGFEDIAIGAPQEDDLRGAVYIYNGRVDGISSTYSQRIEGQQISKSLRMFGQSISGQI-DADNNGYVDVAVGAFQSDSAVLLRTRPVV-------IVEASLSHPESVNRTKFDCTENGLPSVCMHLTLCFSYKGKEV---PGYI---VLFYNVSLDVHRKAESPSRFYFFSNGTSDVI-TGSIRVSSSGEKCRT-----HQAFMRKDVRDILTPIHVEATYHLGHHVITKRNTEEFPPLQ----PILQQKKEKDVIRKMINFARFCAYENCSADLQVSAKVGFLKPYENKTY-LAVGSMKTIMLNV 661
BLAST of Alpha-int-3 vs. Ensembl Mouse
Match: Itga6 (integrin alpha 6 [Source:MGI Symbol;Acc:MGI:96605]) HSP 1 Score: 169.859 bits (429), Expect = 3.431e-42 Identity = 290/1148 (25.26%), Postives = 476/1148 (41.46%), Query Frame = 3
Query: 66 FIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ-NSIKYFLIGAPFD---ILKDSNETTGALFSCPVTKETQDCKKFVF-------SEHSNESLLGYVVDSNSHEGLIYTCAPKF-LRSHTYVKY----VEGACWEFNEMFNEVEQISNQD---CLESIKSESQNYEYRNCLTG-AALKSLERKQLVLTAPYSYEGKGLLI----NNNFYSRENSRSSNYLKFRNSNSKYQ--------YTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIF-GEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQV----FVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPS-YASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHF-GVGCSPGS-CQPILTMQAVLSLPTEGEQ----YILHMGNVSKFKLEIQTK---NIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAV-NSPLNARQSDNAT-FECMLPNDFIENVKESIY----------------INISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKF---TIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLP--NISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
++L + L ++N+D + + S FGFSL + Q + L+GAP L+ +N T G L+SC +T C + F SE + +G V S G + TCA ++ R H K + G C+ ++ + + D C ++ + + +C G AA + + +V AP +Y KG++ NN F+ Y ++ Y GFS+ GK + + + V G+P R V++ + ++++ IF GE S +GY V +DLN DG ++V+GAP + +G+V +VY N + SN+ K I L+ K + +GIS++NIGDIN+D D+AVGAP+ D G V+IY G II K +Q +EG SP +G+SI G N DLD N+YPD VGS LS V R+RP+I + V P D +K C+K+ Y T PS Y +I +E + K+ S R+ F N+ + + T N + + N+ + PI IT S+ + E R ++ P+L + T +HF GC + C L ++ EG Q Y+ + + L+ Q I T+ R DA + L + PD T ++ + A L+ + N + +C L N F N + Y IN+ +E S Q +L PI K KV + + + + P Y +++G ++ E+++G +++ I L ++N + ++ L I +P EIS +G++LLYL+++ + G ++I C P +++ ++LK+ +LP I D KF S+ ++C + RCV + C PL + +L R+W T +E + K Y+DI L+ + + N KLP +VRV K S + I++AV AG+++LA +V +L+KC FF+R
Sbjct: 9 LLYLSAGLLARLGTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRT-GGLYSCDITSRGP-CTRIEFDNDADPMSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK---FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETDHDESLVPVPANSYLGFSLDSGKGIVSKDDITFVSGAP--------RANHSGAVVLLKRDMKSAHLLPEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDRDGEVGGAVYVYINQQGKWSNV--KPIRLNGTK-----------DSMFGISVKNIGDINQDGYPDIAVGAPY--DDLGKVFIYHGSPTGIITKPTQVLEG--TSP---YFGYSIAG-NMDLDRNSYPDLAVGS-LSDSVTIFRSRPVINILKTITVT------PNRIDLRQKSMCGSPSGICLKVKACFEY-----TAKPSGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEPKYTQEL---TLNRQKQRACMEETLWLQENIRDKLR-PIPITA--SVEIQEPSSRRRVNSLPEV---LPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGT-REGNQDKFSYLPIQKGIPELVLKDQKDIALEITVTNSPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV-YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLKN--LGTATLNIQWPKEIS------NGKWLLYLMKVE----SKGLEQIVCE--------------------PHNEINYLKLKESHNSRKKRELPEKQIDDSRKF--------SLFPERKYQTLNC-SVNVRCVNIRC---PLRGLDSKASLVLRSRLWNSTFLEEY--SKLNYLDI------LLRASIDVTAAAQNI-KLPH-AGTQVRVTVFP-SKTVAQYSGVAWWIILLAVLAGILMLALLVFLLWKCGFFKR 1044
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Match: sp|P17852|ITA3_CRIGR (Integrin alpha-3 OS=Cricetulus griseus OX=10029 GN=ITGA3 PE=1 SV=3) HSP 1 Score: 212.231 bits (539), Expect = 1.225e-54 Identity = 278/1137 (24.45%), Postives = 477/1137 (41.95%), Query Frame = 3
Query: 33 PNDLKFMEFINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVE------QISNQDCLESIKSE--SQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKI-EGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKT----SSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSN-NPDRKTSTSSGLIYAVNSPL--NARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGS-------ISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLP-----DIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
P D +M + + L + F++N+D +K +N S FG+S+ + + +Y L+ GAP D+ T TGA++ CP+T DC++ SE S+ + LG V S G + CA H Y + + + M + Q+ D ++ +E + N +Y C G + + + AP +Y KG N+ R++ S Y + + Y G+++ VG +P ++V G+P R Q ++ + L+ V+ G G+ +G ++ DLNNDG +L+VGAP+ G V+V+ M+Q+ P LLL S +GIS+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+I G + P L +G+S+ GK D+D N+YPD +VGS LS H+V +R RP+I + +VA P D C P + V + + Y PSY + T+ Y +E D + S+ F L+ +C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T +HF C P + C L M+A +S + + + + K L I N + + +LT + L S+ P + ++ + +P N R FE + ++K + ++ S S Q +L+P+ L ++V L L+ T + +++G + + E +G +K+ + L + +L + +P+E+ T+G++LLY P I N+ C N+ N P++ + ++ P + P P + L D GS + ++ ++ C G ARCV + C P+ S + R+W T IE++ + V +D W L + +P N + DI S V + A ++ ++ +++AVSAG++LL I+I+L+KC FF+R
Sbjct: 9 PGDPGWM--LGALALMVAASGRFAFAFNLDTRFLVVKEA-VNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLSVADGYTNRTGAVYLCPLTALKDDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCA------HRYTQVLWSGMEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEYSYKGSEDQGNLYIGYTVQVGSAVLHPTYITVVAGAP--------RHQHMGAVFLLSQESGGDLKRKQVLEGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVF----MNQAGTSFPDQP-----SLLLHGP---SRSAFGISIASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSGGLLRQPQQIVHGDKLGLPGLSTFGYSLSGKM-DVDDNSYPDLLVGS-LSDHIVLLRARPVINILQRTLVAR-----PAVLDP-SLCT------PTSCVQVELCFAYNQSAGNPSYRRNITLAYTLEADRDRRPPRLRFARSQSAVFHGFLSMP----ETHCQT--LELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGMRSL-------------DAYPVLNQAQALENHTEVHFQKECGPDNKCDSNLQMRAAFVSEQLQPLSRLQYSRDTKKLFLSINVTNTPSRERAGEDAHEALLTLEVPPALLLSSVRPSGTCQANETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLKAQLQLSTS----SHQDNLQPMTLILQVDYTLQASLSLM-THRLQSFFGGTVMGEAGMKTVEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEV------TNGKWLLY----PTEIIIHSNESWPCQPP--GNLVN-----------PLNLI-------LSDPGDKPHSPQ--RRRRQLDPGGDQGSPPVTLAAAKKAKSETVLTCASGRARCVWLEC---PIPDTSNVTNVTVKARVWNSTFIEDYRDFDRVRVD---GWATLF---LRTSIPTINMENKTTWFSVDIDSELVEELPAEIE----------LWLVLVAVSAGLLLLGLIIILLWKCGFFKR 1021
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Match: sp|Q62470|ITA3_MOUSE (Integrin alpha-3 OS=Mus musculus OX=10090 GN=Itga3 PE=1 SV=1) HSP 1 Score: 207.994 bits (528), Expect = 2.597e-53 Identity = 252/1041 (24.21%), Postives = 435/1041 (41.79%), Query Frame = 3
Query: 105 FSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDIL--KDSNETTGALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVE------QISNQDCLESIKSE--SQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQ-YTGFSMAVGKIFRNP-NVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIE-------LDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYIN----------------ISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID 3050
F++N+D +K +N S FG+S+ + + +Y L+ GAP D+ D TGA++ CP+T DC++ SE S+ + LG V S G + CA H Y K + + M + Q+ D ++ +E + N +Y C G + + + AP +Y KG N+ R++ S Y +R S + Y G+++ VG +P ++ ++V G+P R Q ++ + L+ V+ G G+ +G ++ DLNNDG +L+VGAP+ G V+V+ M+Q+ P LLL S +GIS+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ GK D+D N YPD +VGS LS H+V +R RP+I + +VA P D C + C++ V + + Y P+Y + T+ Y +E + F ++ SS F + T +C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T +HF C P + C L M+A LS + + + + K L I N ++ +LT + S L+ + P Q++N T C L N F N + + I + + S Q +L+P++L ++V L L+ N++ + +++G +++ E +G +K+ + L + +L + +P+E+ T+G++LLY I S N C N+ N + + ++ L + ++ P P ++ + + ++ ++ C G ARCV + C PL S + R+W T IE++ + V +D
Sbjct: 31 FAFNLDTRFLVVKEA-VNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCA------HRYTKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEY-SYRGSEEQGNLYIGYTVQVGNAILHPTDIITVVTGAP--------RHQHMGAVFLLKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVF----MNQAGASFPDQP-----SLLLHGP---SRSAFGISIASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSGGLLRQPQQIIHGEKLGLPGLATFGYSLSGK-MDVDENLYPDLLVGS-LSDHIVLLRARPVINILHRTLVAR-----PAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFARSQSSVFHGFFSMPET-------HCQT--LELLLMDNVRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDA-------------YPVLNQAQAMENHTEVHFQKECGPDNKCDSNLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGEDAHEALLTLE----------------VPSALLLSSVRPSGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQLSTSSHQDNLQPVLLTLQVDYTLQASLSLM----NHRLQSFFGGTVMGEAAMKTAEDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEV------TNGKWLLYPTEITIHS----NGSWPCQPS--GNLVNPLNLTLSDP--GVTPLSPQRRRRQLDPGGDQSSPPVT-----------LAAAKKAKSETVLTCSNGRARCVWLEC---PLPDTSNITNVTVKARVWNSTFIEDYKDFDRVRVD 953
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Match: sp|Q24247|ITA1_DROME (Integrin alpha-PS1 OS=Drosophila melanogaster OX=7227 GN=mew PE=1 SV=2) HSP 1 Score: 201.445 bits (511), Expect = 3.524e-51 Identity = 257/1099 (23.38%), Postives = 456/1099 (41.49%), Query Frame = 3
Query: 63 NFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ----NSIKYFLIGAPFDILKDSNET-TGALFSCPVTKETQDCKKFVFSEHSN----------------ESLLGYVVDSNSHE-----GLIYTCAPKFLRSHTYVKYVEGACWEFNE--MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSRENSRS-SNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVI-GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMIS---PD---LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKL----SVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISL---PIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGS-CQPILTMQAVLSL-PTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATF-------ECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSL---LGFSSITGEEKIGP----------KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDG-QYLLYLLRIPKFSITTGNKKIACN-VDILNNITNVIKTRIYQDIIPISKL------------------------------EDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
N L + + +++N++ P +K + + S FG+S+ T + N L+GAP D + N T +GAL+ CP+T+ DC++ + N + +G V SN + G + CA +++ +Y +G C+ F EV ++ C + + Q+ +Y C G + L+ +VL +P Y +G + + + R+ + S++ + KY Y G S+ G+ F + S G+P R++ GQVVI K +N + ++ GE FGS +GY + D+N D +L+V AP FT G V+VY NI+ T+P+ + L LT + ++G++L NIGD+NKD +DLAVGAP+E G G VYIYLG S + K +QKI+ + P+ +R +G SI G N DLD N+YPD ++G+ S V + RPII + E P + L SN + C S+ Y ++T D+ + F +KR +++ V G C+ + NT +I PV SL P+ + LN P+L++ + ++ F C C+ L ++ ++ + G +Y L + + ++ ++ I N+A + A+ + + + A + + P T S S N D TF + + P++ I + I+ N + + + P+R R L++ V A ++ + P+ Y S+ + ++ T E GP FTI N S +++I++P+ + +P QYLLYL ++P ++ G +A V+ LN + + Y ++ +D Q + V + + + + + P+ S++ + + ++IV +DC +G+ CV + CD+ + S E + R+W TL+ + + + V I
Sbjct: 18 NLGILIILQCVLTCYNFNLEQRLPIVK--YGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEV----HEPC-KGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH---MSYAAGAP--------RSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQ--------DTLPM--KYTLKLTGPLE---SRFGLALANIGDLNKDNCEDLAVGAPYE--GNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISG-NTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASN---LTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA--NTRDIQTPVRFRLKYSLVEPPLADSALVRLN--------------------PILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLIL-DETELEVRINVSNLA----DSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKI--MLFHIFANTTSKLVGPERPERD--LRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIF---NEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAAN-GKKQDIVELDCNKGATNCVRIECDILNMPALS-EAQVVVKARLWNSTLVSEYPRVERVRI 1042
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Match: sp|F1MMS9|ITA3_BOVIN (Integrin alpha-3 OS=Bos taurus OX=9913 GN=ITGA3 PE=3 SV=1) HSP 1 Score: 190.274 bits (482), Expect = 8.357e-48 Identity = 217/898 (24.16%), Postives = 377/898 (41.98%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFSEHSN------ESLLGYVVDSNSHEGLIYTCAPKFL----------RSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGG----GSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSPGS-CQPILTMQAV-LSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSN-NPDRKTSTSSGLIYAVNSPL--NARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACN 2684
++N+D +K N S FG+S+ + + +Y L+ GAP D+ T TGA++ CP+T DC++ E SN + LG V S G + CA ++ R YV G E + ++ + N+ C S + E C G + + + AP +Y KG N+ R++ S Y + Y G++M VG +P +IV G+P R Q ++ + L V+ G G+ +G ++ DLNNDG +L+VGAP+ G ++++ N + S +H ++ L R +G S+ +IGD+N+D QD+AVGAPFE G G VYIY G S +++ Q+ I G+ + P L +G+S+ G+ D+D N YPD +VGS LS +V +R RP+I + + +VA+ + P +F + C + V + + Y P+Y + T+ Y +E D + RL+F + V G + C+T + + N + L P+ + N SLP+ + + L + + YPVL + + +T + F C + C L M+A +S + + + ++ K L I N + +LT + L S+ P + ++ + +P N R FE + ++ + ++ S S Q LRP+ L + V L ++ N++ + +++G S + E +G +K+ + + L + +L + +P+E+S +G++LLY P GN C
Sbjct: 32 AFNLDTRFLVVKEAG-NPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVPDGYTNRTGAVYLCPLTAHKNDCERMDIKEKSNPNHIIEDMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDAR-DDWQTYHNEMC----NSNTDYLETGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKDWDLSEYSYKDPEDQGNLYIGYTMQVGSAILHPTNITIVTGAP--------RHQHVGAVFLLSQEAGGDLRRRQVLEGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYIFMN-QAGTSFPDHPSLLLHGPSR-----------SAFGFSVASIGDVNQDGFQDIAVGAPFE--GLGKVYIYHGSSRGLLRQPQQVIHGEQLGLPGLATFGYSLSGQM-DVDENFYPDLLVGS-LSDRIVLLRARPVINILHKTLVAKPSILDP-AFCTATSC-----------VQVELCFAYNQSAGNPNYRRNITLAYTLEAD----RDRRPPRLHFARSQSAVFHGFFSMPEMRCQT--LELLLMDNVRDKLRPITISMNYSLPLRLPDRPQLGLGSLDA-------------YPVLNQAQALENHTEVQFQKECGQDNRCDSNLQMRAAFVSELGQRLSRLQYRRDLRKLLLSINVTNTPSRKRAGEDAHEALLTLEVPPTLLLSSVRPPGACQANETIVCELGNPFKRNQRMELLIAFEVIGVTLHTRELQAQLQLSTS----SHQDDLRPMTLPLLVDYTLQASLSMV----NHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLAALGTLVLGLEWPYEVS------NGKWLLY----PTEITVHGNGSWHCQ 846
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Match: sp|P26006|ITA3_HUMAN (Integrin alpha-3 OS=Homo sapiens OX=9606 GN=ITGA3 PE=1 SV=5) HSP 1 Score: 173.711 bits (439), Expect = 1.444e-42 Identity = 223/915 (24.37%), Postives = 381/915 (41.64%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDSNET--TGALFSCPVTKETQDCKKFVFS------EHSNESL-LGYVVDSNSHEGLIYTCAPKFLR----SHTYVKYVEGACWEFNEMFNEVEQISNQDCL----ESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQK-IEGQMIS-PDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSII--NTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGCSP-GSCQPILTMQAVLSLPTEGEQYILHMG---NVSKFKLEIQTKNIATT-----DDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVK----------------ESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYRE---DSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACN 2684
++N+D +K N S FG+S+ + + +Y L+ GAP ++ T TGA++ CP+T DC++ + H E + LG V S G + CA ++ + + + G C+ N++E S+ D E S + E C G + + + AP +Y KG N+ R+ S Y + Y G++M VG +P +IV G+P R + ++ + L V+ G G+ +G ++ DLNNDG +L+VGAP+ G ++V+ M+Q+ P LLL S +G+S+ +IGDIN+D QD+AVGAPFE G G VYIY S +++ Q+ I G+ + P L +G+S+ G+ D+D N YPD +VGS LS H+V +R RP+I N+V +T + P D C + C++ V + + Y P+Y + T+ Y +E + RL F + V G + K ++ N + L P+ + N SLP+ + + L + + YP+L + + +T + F C P C+ L M+A +E +Q + + +V K L I N T+ D ++A T ++ L+ + P A Q++ F C L N F N + + + + + S Q +L P++L + V L ++ N++ + +++G S + E +G +K+ + + V L + +L + +P+E+S +G++LLY P GN C
Sbjct: 32 AFNLDTRFLVVKEAG-NPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRG---NDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTS-GGFTQNTVYFGAPGAYNWKG---NSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAP--------RHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVF----MNQAGTSFPAHP-----SLLLHGP---SGSAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ-MDVDENFYPDLLVGS-LSDHIVLLRARPVI-----NIVHKTLVPRPAVLDP-ALCTATS----CVQ--VELCFAYNQSAGNPNYRRNITLAYTLEA----DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA-------------YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFV--SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV---------------------PPALLLSSVRPPGACQANETIF-CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTLQTSLSMV----NHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVS------NGKWLLY----PTEITVHGNGSWPCR 847
BLAST of Alpha-int-3 vs. TrEMBL
Match: A0A1P8CUU3 (Alpha-int-3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1684.85 bits (4362), Expect = 0.000e+0 Identity = 840/859 (97.79%), Postives = 844/859 (98.25%), Query Frame = 3
Query: 744 MAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK 3320
MAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGD HQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIK + + LYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRN LSDDLADLSNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQ KNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFEC+LPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKF+IALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK
Sbjct: 1 MAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDRHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKPFAGRCLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNFLSDDLADLSNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQMKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECLLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFSIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK--------KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK 851
BLAST of Alpha-int-3 vs. TrEMBL
Match: A0A068YDF9 (Integrin alpha ps OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000782500 PE=3 SV=1) HSP 1 Score: 248.825 bits (634), Expect = 1.166e-63 Identity = 283/1157 (24.46%), Postives = 501/1157 (43.30%), Query Frame = 3
Query: 204 QNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFSEHSNE---------SLLGYVVDSNSHEG--LIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAA---LKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYL---KFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQ-VVIGKLIENS-----LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNN--------------------GQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLS-NGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMP--------CIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDM---------PFIKTSSSK-----RLYFENKLNTVTGG-------GSINCKTPNSKSNSII------------------------NTFNILFPVNLFF------NISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPD---RKTSTSSGL-IYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIV-----LKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGP-KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSIT----TGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVP-KLPNISD--EIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKR 3311
QN+ + ++GAPFD +G+++ CP ++ C++ F H + L G+ + + E L C+P+ T +V G C+ F+ + N + CL +I S++ + R CL GA+ + +V +PY KG+ + NN R ++ + S + + P V V G+PG+ Q TQ + G V+ +IE + V ++ G FGS +G++V +DL+ DG D+LVVGAPF G ++V+WN Q T D ++ LS +G S+ ++GDI++D I D AVGAP++ +G GAV IY G + I L +Q + ++ ++G+GFS+ DLD+N YPD VG+ S + R RP+I+V + + + DSL+ C + Q +P C+ + V + + DL C + +TI + L + F +SSK +F ++ V S + TP + S+ ++ + PV L F ++S PI +KW L+ S ADL NYP+ +N + I FG C C PIL Q S+ + + ++ +G+ +E++ + + ++ T + +Y + ++L +N + R + GL + +PL+ + + + ++ IN +I A SP+ + + + +KVKM N+ + + PD Y + G GE KIG ++ + ++N ++S++ +S+L+I +P+E + TE +G+ L YLL P + T N I C+ L+ + N R+++ + P + + V + +P++ P + P + EI+ +P + +S + C+ G RCVP+VCDLGPLS ++G +T + R+W +T+ ++F + + W V + G+ D S + + N +P+P ++ I +AV G++LLA ++IIL+K FF R+ +R
Sbjct: 2 QNNGEGIIVGAPFD------NNSGSIYWCPY--KSNQCRRVNFDIHKSAHYSYSKLGNELFGFSLSTLPKERNRLAVACSPRLSYEVTGNLFVTGGCFAFDNVLNNPSFLGASSCL-NIPEASRSIDLRFCLDGASSAYFHNTYTDLIVSGSPYYQFAKGIGLVNNVTKFNPVRKTDIAYVGDYSLLGSSSVLSDRVYSSASDSERPIVS--VFGAPGVPQ-----TQDREGSGFVVLHVIEKGPNQIVIPQVKILHGNRFGSRFGHAVALIDLDCDGWDDLVVGAPFEQLPGTSVALQRDFDLHGVHSAPVFGCIYVFWN----QRRHLPSTTAFDSTSVQVIWPPPSLSFKSGFGSSITSLGDIDRDGIDDFAVGAPYD-EGGGAVLIYHGSKSRRIGLPTQILNATELTDSMKGFGFSLSSGGLDLDNNGYPDLAVGAPNSDKIAVFRARPVIKVEIFVLREDGSSHIGERLDSLEVCTRDTQILPGYWAPRVHCMNMKVLATFTHLDLVPC----ARRTIPVRLLLTINPPDHWLNEEFTNKTSSKTETPVASFFGERVLKVGDPEVGEFYQRSYDAATPPANSDEVLPFLLLNSLMAICREPGDTNKPPSPAELDQATPVRLAFRDVDLVDLSSPIRFGVKWLLDAPS------PSSPFADLINYPINNPRENTGQSLITFGNECESRKCNPILLPQFEYSVTRDRDGPVVFVGDDEFQSVEVKA-TVTNRGRDPSYATSVYASYPEELLDLSTNQHELNHRVSLVRPGLALCHFGNPLSVGEGATCALRFKVLGQQLMKAPKNFTINSTI-ASSPKFPPKMLASATDSITVKVKMSVNVSVTGEILPDAAYYSGNVTDGILINNGENKIGSTRLLIRVRVQNLRKHSLVPNSRLIIDWPYETADIITEENGKLLFYLLEKPYITKTDLPIASNTTIVCDSRALDRLVNPYNYRVFRSLAPQPRGDPVATAPIDLPSSHPTEYPPLKSNLEIEKMPDQGNVKRVS-----TTLSCYNGQLRCVPIVCDLGPLSYRTGMLTFEMPARLWDNTMRQDFKDIFMTSVQLTATW----RASVTFTIDAGDK----DHTSGNLELKIFNDMEPEPVYPKNMPLYIGLAVFTGLLLLAILIIILWKAKFFERKKFKQR 1112
BLAST of Alpha-int-3 vs. TrEMBL
Match: A0A068WCN4 (Integrin alpha ps OS=Echinococcus granulosus OX=6210 GN=EgrG_000782500 PE=3 SV=1) HSP 1 Score: 239.58 bits (610), Expect = 1.009e-60 Identity = 282/1150 (24.52%), Postives = 492/1150 (42.78%), Query Frame = 3
Query: 204 QNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFSEHSNE---------SLLGYVVDSNSHEG--LIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINN--NFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENS-----LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNN--------------------GQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLS-NGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGD-SHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMP--------CIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDM---------PFIKTSSSK-----RLYFENKLNTVTGG-------GSINCKTPNSKSNSII------------------------NTFNILFPVNLFF------NISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPD----RKTSTSSGL-IYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMS--PQRHLRPIV--LKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGP-KMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFS----ITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVP-KLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKR 3311
QN+ + ++GAPFD +G+++ CP ++ C++ F H + L G+ + + E L C+P+ T +V G C+ F+ + + CL +I S++ + R CL GA+ L G+ L+NN F + + + S + + P V V G+PG+ Q T + G VV+ +IE + V V+ G FGS +G++V +DL+ DG D+LVVGAPF G ++V+WN Q T D ++ LS +G S+ ++GDI+ D I D AVGAP++ +G GAV IY G S +I +Q + ++ + G+GFS+ DLD+N YPD VG+ S + R RP+I++ + + + DSL+ C + Q +P C+ + V + + D C + +TI + L + F +SSK +F ++ V S + TP + S+ ++ + PV L F ++S PI +KW L+ S ADL NYP+ +N + I FG C C PIL Q S+ + + ++ +G+ +E++ + + ++ T + +Y + ++L S NP R + GL + +PL+ + + + ++ IN +I + P + L P + +KVKM N+ + + PD Y + G GE KIG ++ + ++N ++S++ +S+L+I +P+E + TE +G+ L YLL P + T N I C+ L+ + N R+++ + P + + V + +P++ P + P + ++F K D G++ + C+ G RCVP+VCDLGPLS ++G +T + R+W +T+ ++F + + W V + G+ D S + + N +P+P ++ I +AV AG++LLA ++IIL+K FF R+ +R
Sbjct: 2 QNNGEGIIVGAPFD------NNSGSIYWCPY--KSNQCRRVNFDIHKSAHYSYSKLGNELFGFSLSTLPKERNRLAVACSPRLSYEVTGNLFVTGGCFAFDNVLINPSFLGASSCL-NIPEASRSIDLRFCLDGASSAYFHNTYTDLIV----SGRIGLVNNVTKFNPVRKTDIAYVGDYSLLGSSSVLSDRVYSSASDSERPIVS--VFGAPGVPQ---TWDREGSGFVVL-NVIEKGPNQIVIPQVKVLHGNRFGSRFGHAVALIDLDCDGWDDLVVGAPFEQLPGTSVALQRDLDLHSVHSAPVFGCIYVFWN----QRRHLPSTTAFDSTSVQVIWPPPSLSFKSGFGSSITSLGDIDHDGIDDFAVGAPYD-EGGGAVLIYHGSKSRRIGAPTQILNATELTDSMEGFGFSLSSGGLDLDNNGYPDLAVGAPNSDKIAVFRARPVIKLEIFVLREDGSSHIGERLDSLEVCTRDTQILPGYWAPRVHCMNMKVLATFTHLDPVPC----ARRTIPVRLLLTINPPDHWLNEEFTNKNSSKMEIPVASFFGEQVLKVGDPEVGEFYRRSYDAATPPANSDEVLPFLLLNSLMAVCREPGATNKPPSPAELDQATPVRLAFRDVDLVDLSSPIRFGVKWLLDAPS------PSSPFADLINYPINNPRENTGQSLITFGNECESRKCNPILLPQFEYSVTRDRDGPVVRVGDDEFQSVEVKA-TVTNRGRDPSYATSVYASYPEELLDL-STNPHELNHRASLVRPGLALCHFGNPLSVGEGATCALRFKVLGQQLMKAPKNFTINSTITSSPKFPPKMLAPATDSITVKVKMSVNVSVTGEILPDAAYYSGNVTDGILINNGENKIGSTRLLIRVRVQNLRKHSLVPNSRLIIDWPYETADIITEENGKLLFYLLEKPYITKTDLPTASNTTIVCDSRALDRLVNPYNYRVFRSLAPQPRGDPVATAPIDLPSSHPTEYPPLKSNLEF-EKMPDQGNVKRVSTT--LSCYNGQLRCVPIVCDLGPLSYRTGILTFEMPARLWDNTMRQDFKDIFMTSVQLTATW----RASVTFTIDAGDK----DHTSDNLELKIFNDMEPEPVYPKNMPLYIGLAVFAGLLLLAILIIILWKAKFFERKKFKQR 1104
BLAST of Alpha-int-3 vs. TrEMBL
Match: A0A1S3R6S0 (integrin alpha-3-like isoform X3 OS=Salmo salar OX=8030 GN=LOC106600863 PE=3 SV=1) HSP 1 Score: 234.958 bits (598), Expect = 2.095e-59 Identity = 287/1130 (25.40%), Postives = 486/1130 (43.01%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFL-IGAPFDILKD---SNETTGALFSCPVTKETQDCKK---------FVFSEHSNESL-LGYVVDSNSHEG-LIYTCAPKFLRSHTYVKYVE--GACW-EFNEM-FNEVE-QISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKG-----LLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNN----NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFG----KNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFE-NKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMK---WSLNVSEVPKRNXXXXXXXXXXNYPVLERVK-NNLTNTIHFGVGCS-PGSCQPILTMQAVLS------LPT-EGEQYILHMGNVSKFKLEIQTKNIAT-----TDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYA-VNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYF--PWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI----------DIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
+N+D+ P +K S FGFS+ + +Y L +GAP + + +NET G +++CPV DC + + E E + LG V S G I TC +F++ H +K + G C+ N++ +NE + N D + S + N AA+ E +++ AP S+E +G + N Y + S N+ N ++ Y G+S+A G+ + N ++V G+P ++ D+ + I + + L+ + GE GS +G S+ DLNNDG ++L+VGAPF + G V+VY N + K+ + ++ + +G+++ IGD+N+D QD AVGAPF GTG VYI+ G + I + SQ I+G+ D+ G GF FG D+D N YPD +VGS L V +R RP+I + V P D K C++ C+++ V Y T + + T+ Y +E D+ T + R+ F+ N L++ TG S+ P++K + L ++ PI ++ +SLNVS + L +L +PVL K +++ IHF C +CQ L M+A + P+ +G Q + + NV K L ++ N + D + A I L Y A + L++N+P K S ++ + +P + Q D + + I I + + +S Q +L+P+ L + V+ + L + + + ++G S + +G ++FT + N + L + F PWE++ +G++LLYL I T G C I N +K ++P SK + ++ + P+ P S +K K S +DC G+A CV +C PL + T+ R+W T++E++ + V + D P + + L + P++ A Q P ++ II++ AGV+LLA I+++++KC FFRR
Sbjct: 30 GFNLDVRFPVVKEGKTPG-SLFGFSVALHKQMVGEKRYLLLVGAPKEKAESGVKANET-GDVYTCPVNVAQSDCTRMNLIGSDPDLIEGEDRVEDMWLGVTVASQRQPGGRILTCGHRFVKLHGVLKLRQMIGKCYIRGNDLNYNETDMHWQNPDQVCSHTKDITGEVMCNMGISAAITDTE---VIVGAPGSFEWQGNVHVSWMNPNVIYDTKRSSFPNF-----GNRRHIYIGYSVAEGRGLLSQNQDTVVTGAPKDNKDDAKGSVILTVKKKSTSGDGDQLKPYLTLRGEQMGSYFGNSLAVADLNNDGWNDLIVGAPFYFDRKKELGGAVYVYMN---ENGSFRQKSSII----------LRGPRDSAFGMAVAAIGDVNQDGFQDFAVGAPFH--GTGRVYIWTGSAEGISREPSQVIDGE----DIAGGGFKTFGYSINGGLDVDENRYPDMVVGS-LDDRVALLRARPVIHLIKTLEVT------PEIVDP-KDCDN------CVEVKVCFSYTLS--TGANDFRKNVTVKYTVEADL----TRHNHRVRFQDNGLDSYTGFLSM----PSAKCKT------------LRLGLASPIRDKVEPVVFSLNVSLHEGHSKARQSLQNLDAFPVLSEGKASHVKKEIHFQKACGLDNTCQSNLQMKAEFANEEQTPFPSHDGHQILQYSANVKKVMLVVEVTNFPSPGKPAEDAHNAMLNVTIPPSLIYSAFRSKLWNNSPAIKCSAEDMVVLCELGNPFTSNQMDQV--QIIFQTSEISLDTREIRSTLQLSTLSKQSNLQPLPLVMMVEYTLDTSFALAQYTGHTHFSGE-IMGESGMKTASDVGSPVEFTFKV-NVFGKPLGNLGNLEVEFDWPWEVA------NGKWLLYLTEIQ----TKGTSDSHCVPP--GAIVNPLKL-----MLPESKARRRKREEGSTEEVHPREPQASLNLKGTRKKS-----------FKLDCVTGAAHCVKFIC---PLRNMNNTATIIVRARVWNSTMLEDYREAWRVTVNGKATLKLVTDKPTIRMNTESTEFTLNID-------PELGEE------ATYQVP--------LWIIIVSAVAGVLLLAFIILLMWKCGFFRR 1038
BLAST of Alpha-int-3 vs. TrEMBL
Match: A0A1S3R7F9 (integrin alpha-3-like isoform X1 OS=Salmo salar OX=8030 GN=LOC106600863 PE=3 SV=1) HSP 1 Score: 234.572 bits (597), Expect = 3.342e-59 Identity = 287/1132 (25.35%), Postives = 487/1132 (43.02%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFL-IGAPFDILKD---SNETTGALFSCPVTKETQDCKK---------FVFSEHSNESL-LGYVVDSNSHEG-LIYTCAPKFLRSHTYVKYVE--GACW-EFNEM-FNEVE-QISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKG-----LLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNN----NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRGYGFSIFG----KNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFE-NKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMK---WSLNVSEVPKRNXXXXXXXXXXNYPVLERVK-NNLTNTIHFGVGCS-PGSCQPILTMQAVLS------LPT-EGEQYILHMGNVSKFKLEIQTKNIAT-----TDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYA-VNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYF--PWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI----------DIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQN 3299
+N+D+ P +K S FGFS+ + +Y L +GAP + + +NET G +++CPV DC + + E E + LG V S G I TC +F++ H +K + G C+ N++ +NE + N D + S + N AA+ E +++ AP S+E +G + N Y + S N+ N ++ Y G+S+A G+ + N ++V G+P ++ D+ + I + + L+ + GE GS +G S+ DLNNDG ++L+VGAPF + G V+VY N + K+ + ++ + +G+++ IGD+N+D QD AVGAPF GTG VYI+ G + I + SQ I+G+ D+ G GF FG D+D N YPD +VGS L V +R RP+I + V P D K C++ C+++ V Y T + + T+ Y +E D+ T + R+ F+ N L++ TG S+ P++K + L ++ PI ++ +SLNVS + L +L +PVL K +++ IHF C +CQ L M+A + P+ +G Q + + NV K L ++ N + D + A I L Y A + L++N+P K S ++ + +P + Q D + + I I + + +S Q +L+P+ L + V+ + L + + + ++G S + +G ++FT + N + L + F PWE++ +G++LLYL I T G C I N +K ++P SK + ++ + P+ P S +K K S +DC G+A CV +C PL + T+ R+W T++E++ + V + D P + + L + P++ A Q P ++ II++ AGV+LLA I+++++KC FF+R N
Sbjct: 30 GFNLDVRFPVVKEGKTPG-SLFGFSVALHKQMVGEKRYLLLVGAPKEKAESGVKANET-GDVYTCPVNVAQSDCTRMNLIGSDPDLIEGEDRVEDMWLGVTVASQRQPGGRILTCGHRFVKLHGVLKLRQMIGKCYIRGNDLNYNETDMHWQNPDQVCSHTKDITGEVMCNMGISAAITDTE---VIVGAPGSFEWQGNVHVSWMNPNVIYDTKRSSFPNF-----GNRRHIYIGYSVAEGRGLLSQNQDTVVTGAPKDNKDDAKGSVILTVKKKSTSGDGDQLKPYLTLRGEQMGSYFGNSLAVADLNNDGWNDLIVGAPFYFDRKKELGGAVYVYMN---ENGSFRQKSSII----------LRGPRDSAFGMAVAAIGDVNQDGFQDFAVGAPFH--GTGRVYIWTGSAEGISREPSQVIDGE----DIAGGGFKTFGYSINGGLDVDENRYPDMVVGS-LDDRVALLRARPVIHLIKTLEVT------PEIVDP-KDCDN------CVEVKVCFSYTLS--TGANDFRKNVTVKYTVEADL----TRHNHRVRFQDNGLDSYTGFLSM----PSAKCKT------------LRLGLASPIRDKVEPVVFSLNVSLHEGHSKARQSLQNLDAFPVLSEGKASHVKKEIHFQKACGLDNTCQSNLQMKAEFANEEQTPFPSHDGHQILQYSANVKKVMLVVEVTNFPSPGKPAEDAHNAMLNVTIPPSLIYSAFRSKLWNNSPAIKCSAEDMVVLCELGNPFTSNQMDQV--QIIFQTSEISLDTREIRSTLQLSTLSKQSNLQPLPLVMMVEYTLDTSFALAQYTGHTHFSGE-IMGESGMKTASDVGSPVEFTFKV-NVFGKPLGNLGNLEVEFDWPWEVA------NGKWLLYLTEIQ----TKGTSDSHCVPP--GAIVNPLKL-----MLPESKARRRKREEGSTEEVHPREPQASLNLKGTRKKS-----------FKLDCVTGAAHCVKFIC---PLRNMNNTATIIVRARVWNSTMLEDYREAWRVTVNGKATLKLVTDKPTIRMNTESTEFTLNID-------PELGEE------ATYQVP--------LWIIIVSAVAGVLLLAFIILLMWKCGFFKRPN 1040
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Match: itga6a (integrin subunit alpha 6 [Source:NCBI gene;Acc:103030583]) HSP 1 Score: 189.889 bits (481), Expect = 1.410e-48 Identity = 289/1168 (24.74%), Postives = 481/1168 (41.18%), Query Frame = 3
Query: 66 FIFLFLFHVPVLYF----SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ-NSIKYFLIGAPFD--ILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLR-----SHTYVKYVEGACWEFNEMFNEVEQISNQDC--LESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------LINNNFYSR------ENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENS--LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNT---VTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNI-SLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERV--KNNLTNTIHFGVGCSPGS-CQPILTMQAVLS-----------LPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKA---FRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYI----------------NISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVI-------------YAIIIAVSAGVILLATIVIILYKCNFFRR 3293
F+ + P+L + ++N+D + K + S FGFS+ + Q + LIGAP + TG L+SC +T T DC + F E +G V S G I TCA ++ R S + + G C+ ++ + ++ S++D + + ++ +E + C G AA + + L+ AP +Y KG+ L+ FY + SR + L +NS Y GFS+ G +V G+P R +++GK E S L V ++ G S +GY V +DLN DG +++VVGAP +G+V I M+++ +P+ + + +G+ +E IGDIN D D+AVGAP+ + G+G VYIY G + I K +Q +EG+ ++ +G+S+ G N DLD N+YPD VGS LS V R+RP+I + E V P D KK N I L+V + Y P+Y+ I Y +E + K R+ F++K T GS+ K N ++ + N+ + ++PIE+++ + ++ KR +L PVL+ N T GC + CQ L +Q LP + ++ + + LE+ +N D ++A + +L+Y F ++ + +S +I N N Q+D C L N F + + + YI ++ +E S Q LR + K KV + + ++ + P Y + G S++ EE +G + + + N + + L I +P E S G++LLYL++I + ++I C+ + N+ + + R + + + K +V T+ K +S C G ARCV + C L L S +I L+ R+W T IE F Y Y+D+ +V + L V N IV L+ P+ L V + I++AV AG+++LA +V++L+KC FF+R
Sbjct: 7 FVGFSWWISPLLLWTGAAAFNLDTQTVLRKDG--DPGSLFGFSIALHRQLQPEDRRILLIGAPRAKALAYQRANITGGLYSCDITAHTDDCNRIEFDNEADAQKESKENQWMGVTVQSQGPGGKIVTCAHRYQRRLFVNSPQESRDITGRCYVLSQDLS-IDSQSDEDGGNWKFCEGRARGHERFGACQQGLAAAFTNDYHYLIFGAPGAYNWKGIVRVEQKNNTLLEMGFYDDGPYEVGDESRLNPELVPVPANS---YLGFSLDSGHSITEKGKLIVVSGAP--------RANHSGAVILLGKEGEVSSMLSPVYILEGPGLASSFGYDVAVVDLNGDGWEDIVVGAPQFFQRDGEVGGAVYIYMNRAGKWSSVVPI---------RLNGTKDSMFGLVVEKIGDINLDSYDDIAVGAPYADGGSGRVYIYHGSADGINTKAAQVLEGKQHG--IKMFGYSLAG-NMDLDENSYPDLAVGS-LSDSVFIYRSRPVITMTKEIKVT------PREIDLTKKTCGN-----SICLNVEACFTYK--ANPPTYSPKLRISYTLEAESVRRKQGMPSRVSFQDKKPTDQDFQSTGSLELKGQNKRA---CYKTKLRLQENIKDKLRAIPIEVSV--DIASAKRGKRQNSLPELV-----PVLDSSLPSKNSTEVNFLKEGCGTDNICQSNLHLQYRFCYRESNQDIFPPLPVKNGVAVVSLSDQKDIALEVTVRNRNGDDAHEAKLVGQFGDLLSYSG-----FRSHRNSMSSKDKQVICVANQ--NGSQAD-----CELGNPFKRDSEVTFYIILSTARISLNTTEVEVDLQLETTSLQEGLRKVRAKAKVMIELLLSVQGIAKPSQV-YFGGVVKGESAMKSEEDVGSLIDYEFRVINLGKPLKSFGTAYLNIQWPKETS------TGRWLLYLVKINSKEL----EEIKCSPEKEINLLGLTE-RSSRKKREAEESRSTETSKTSVFTDQRKYKTLS-------------------------CL-GDARCVEIKCPLLNLD-SSADIILRS--RLWNATFIEEFSSYN--YLDV------IVHASISLNVSAKN------IV----------LKNPETQVRLTVFPENTVAHYGGVPWWIILVAVLAGILMLALLVLLLWKCGFFKR 1047
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Match: itga6a (integrin subunit alpha 6 [Source:NCBI gene;Acc:103030583]) HSP 1 Score: 189.889 bits (481), Expect = 1.410e-48 Identity = 289/1168 (24.74%), Postives = 481/1168 (41.18%), Query Frame = 3
Query: 66 FIFLFLFHVPVLYF----SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ-NSIKYFLIGAPFD--ILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLR-----SHTYVKYVEGACWEFNEMFNEVEQISNQDC--LESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------LINNNFYSR------ENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENS--LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNT---VTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNI-SLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERV--KNNLTNTIHFGVGCSPGS-CQPILTMQAVLS-----------LPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKA---FRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYI----------------NISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVI-------------YAIIIAVSAGVILLATIVIILYKCNFFRR 3293
F+ + P+L + ++N+D + K + S FGFS+ + Q + LIGAP + TG L+SC +T T DC + F E +G V S G I TCA ++ R S + + G C+ ++ + ++ S++D + + ++ +E + C G AA + + L+ AP +Y KG+ L+ FY + SR + L +NS Y GFS+ G +V G+P R +++GK E S L V ++ G S +GY V +DLN DG +++VVGAP +G+V I M+++ +P+ + + +G+ +E IGDIN D D+AVGAP+ + G+G VYIY G + I K +Q +EG+ ++ +G+S+ G N DLD N+YPD VGS LS V R+RP+I + E V P D KK N I L+V + Y P+Y+ I Y +E + K R+ F++K T GS+ K N ++ + N+ + ++PIE+++ + ++ KR +L PVL+ N T GC + CQ L +Q LP + ++ + + LE+ +N D ++A + +L+Y F ++ + +S +I N N Q+D C L N F + + + YI ++ +E S Q LR + K KV + + ++ + P Y + G S++ EE +G + + + N + + L I +P E S G++LLYL++I + ++I C+ + N+ + + R + + + K +V T+ K +S C G ARCV + C L L S +I L+ R+W T IE F Y Y+D+ +V + L V N IV L+ P+ L V + I++AV AG+++LA +V++L+KC FF+R
Sbjct: 7 FVGFSWWISPLLLWTGAAAFNLDTQTVLRKDG--DPGSLFGFSIALHRQLQPEDRRILLIGAPRAKALAYQRANITGGLYSCDITAHTDDCNRIEFDNEADAQKESKENQWMGVTVQSQGPGGKIVTCAHRYQRRLFVNSPQESRDITGRCYVLSQDLS-IDSQSDEDGGNWKFCEGRARGHERFGACQQGLAAAFTNDYHYLIFGAPGAYNWKGIVRVEQKNNTLLEMGFYDDGPYEVGDESRLNPELVPVPANS---YLGFSLDSGHSITEKGKLIVVSGAP--------RANHSGAVILLGKEGEVSSMLSPVYILEGPGLASSFGYDVAVVDLNGDGWEDIVVGAPQFFQRDGEVGGAVYIYMNRAGKWSSVVPI---------RLNGTKDSMFGLVVEKIGDINLDSYDDIAVGAPYADGGSGRVYIYHGSADGINTKAAQVLEGKQHG--IKMFGYSLAG-NMDLDENSYPDLAVGS-LSDSVFIYRSRPVITMTKEIKVT------PREIDLTKKTCGN-----SICLNVEACFTYK--ANPPTYSPKLRISYTLEAESVRRKQGMPSRVSFQDKKPTDQDFQSTGSLELKGQNKRA---CYKTKLRLQENIKDKLRAIPIEVSV--DIASAKRGKRQNSLPELV-----PVLDSSLPSKNSTEVNFLKEGCGTDNICQSNLHLQYRFCYRESNQDIFPPLPVKNGVAVVSLSDQKDIALEVTVRNRNGDDAHEAKLVGQFGDLLSYSG-----FRSHRNSMSSKDKQVICVANQ--NGSQAD-----CELGNPFKRDSEVTFYIILSTARISLNTTEVEVDLQLETTSLQEGLRKVRAKAKVMIELLLSVQGIAKPSQV-YFGGVVKGESAMKSEEDVGSLIDYEFRVINLGKPLKSFGTAYLNIQWPKETS------TGRWLLYLVKINSKEL----EEIKCSPEKEINLLGLTE-RSSRKKREAEESRSTETSKTSVFTDQRKYKTLS-------------------------CL-GDARCVEIKCPLLNLD-SSADIILRS--RLWNATFIEEFSSYN--YLDV------IVHASISLNVSAKN------IV----------LKNPETQVRLTVFPENTVAHYGGVPWWIILVAVLAGILMLALLVLLLWKCGFFKR 1047
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Match: itga3b (integrin alpha-3-like [Source:NCBI gene;Acc:103040573]) HSP 1 Score: 181.8 bits (460), Expect = 4.183e-46 Identity = 260/1023 (25.42%), Postives = 433/1023 (42.33%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLI-GAPFDILKDS---NETTGALFSCPVTKETQDCKKF--VFSEHSNESL----LGYVVDSNSHE--GLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNC---------------LTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIK-LSQKIEGQMI-SPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYF-ENKLNTVTGGGSINCKTPNSKSNSIINTF-NILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVL---ERVKNNLTNTIHFGVGC-SPGSCQPILTMQAVLS----LP---TEGEQYILHMGNVSKFKLEIQTKNIAT--TDDNKAFRTYIILTYDA--KKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTET-DGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENF 3023
+NIDL P +K SFFGFS+ Q KY L+ GAP + + NET GA++SCP+T + DC + + S S+E + LG V S + G + C H YVK V G E M + + D + + QN+ Y C ++G KS + T Y ++G + + S NS N + Y G+S+ + ++V G+P D +R G V + + + L I GE GS +G S+ DLNND ++L+VGAPF G V+V+ N S K+++L MK +GI++ IGDIN+D QD AVGAPF G+G VYI+ G I+K SQ IEG + S + +G+S+ G D+D N YPD +VGS L + +R RP+I+ ++ T P D L +C C+ +V + + Y P + + ++ Y +E D + + R+ F + KLNT TG + + T S+ + N L PV N+SL +E +VP ++ L + +PVL +RV I+F C + C L ++ + +P + Q + + +V K L ++ N+ + A + + LT K L D + + + +I + +P + + N F + I + I + + +S Q L P+ + + V+ + + +N + ++G S + +G +KF + + + + + L + F W P E +G++LLYL I +TTG + C D I N + + + ++ + K + N+P+ ++ + L +S + L+DC + +ARCV C L +S S EIT++ R+W T++E++
Sbjct: 21 GFNIDLRFPVVKEGKTKG-SFFGFSVAQHKQTQKGEKYLLLTGAPREKAPSNLKVNET-GAVYSCPITSDVADCTRMDIITSTDSSEMIEGMWLGVTVASQRDQPDGRVLACG------HRYVKVVPGGIEEQRRMVGKC-YVRGNDLTYDNRDDWQNHPYEVCNHNFDMEKEGMCNMGISGGMTKS--DVYIGCTGSYLWQGN-VHVTWRDTSPGNSWDYNDRDLGQQAKRNSYMGYSVTEETKLLDGTEFTLVTGAP----RDESR-----GSVTLAAVGNSDLVVKVTIPGEQVGSYFGSSIAVTDLNNDNWNDLIVGAPFYFDRYKEQGGAVYVFMNENGSFGG-----------KKMVLKGMK---GSGFGIAVAAIGDINQDGFQDFAVGAPFH--GSGKVYIWTGSKEGIMKDPSQVIEGNSVGSGGFQTFGYSLSG-GMDMDGNKYPDILVGS-LDDRIALLRARPVIQ------LSRTFTVEPKIVDPL-QCKD-----ACV--TVKMCFAYTLSNGNPDFKNKISVKYTVEAD----RALRNPRVQFTDTKLNTNTGVLTFSSSTCQELKLSVTDQIKNKLDPVVFLLNVSL-VE---------PDVPAQSSLQNLDV----FPVLSSQQRVTEKA--EINFQKECGADNKCSSNLQVKKEFANESQVPFSSNDKGQMMEYDNSVVKLTLLLEVSNLPEPGREAEDAHQAMLNLTIPPTLKYSGLRPQGIDIQCTANVTVICDLGNPFKSNKQINFHF---IFQTSITLYTDQIQTQLQLSTLSEQSDLNPVSITLNVRNNIAPSFTIDNSVEN-TFFSGKVMGESGMKTISDVGSPVKFVFKVSVSGEPLGEMGT-LFVVFDW-----PVEVLNGKWLLYLTEI----LTTGTSEQRCVPD--GQIVNPLNLTLSE--------KNSKRNKRDLDVNLPQ----TEAARTL--------LSPRKESHLLDCSKQTARCVTFSCPLTNMS-TSAEITVR--ARVWNTTMLEDY 931
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Match: itga6a (integrin subunit alpha 6 [Source:NCBI gene;Acc:103030583]) HSP 1 Score: 163.31 bits (412), Expect = 3.044e-40 Identity = 168/604 (27.81%), Postives = 266/604 (44.04%), Query Frame = 3
Query: 66 FIFLFLFHVPVLYF----SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQ-NSIKYFLIGAPFD--ILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLR-----SHTYVKYVEGACWEFNEMFNEVEQISNQDC--LESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------LINNNFYSR------ENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENS--LEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQI-IKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNT---VTGGGSINCKTPNSKS 1745
F+ + P+L + ++N+D + K + S FGFS+ + Q + LIGAP + TG L+SC +T T DC + F E +G V S G I TCA ++ R S + + G C+ ++ + ++ S++D + + ++ +E + C G AA + + L+ AP +Y KG+ L+ FY + SR + L +NS Y GFS+ G +V G+P R +++GK E S L V ++ G S +GY V +DLN DG +++VVGAP +G+V I M+++ +P+ + + +G+ +E IGDIN D D+AVGAP+ + G+G VYIY G + I K +Q +EG+ ++ +G+S+ G N DLD N+YPD VGS LS V R+RP+I + E V P D KK N I L+V + Y P+Y+ I Y +E + K R+ F++K T GS+ K N ++
Sbjct: 7 FVGFSWWISPLLLWTGAAAFNLDTQTVLRKDG--DPGSLFGFSIALHRQLQPEDRRILLIGAPRAKALAYQRANITGGLYSCDITAHTDDCNRIEFDNEADAQKESKENQWMGVTVQSQGPGGKIVTCAHRYQRRLFVNSPQESRDITGRCYVLSQDLS-IDSQSDEDGGNWKFCEGRARGHERFGACQQGLAAAFTNDYHYLIFGAPGAYNWKGIVRVEQKNNTLLEMGFYDDGPYEVGDESRLNPELVPVPANS---YLGFSLDSGHSITEKGKLIVVSGAP--------RANHSGAVILLGKEGEVSSMLSPVYILEGPGLASSFGYDVAVVDLNGDGWEDIVVGAPQFFQRDGEVGGAVYIYMNRAGKWSSVVPI---------RLNGTKDSMFGLVVEKIGDINLDSYDDIAVGAPYADGGSGRVYIYHGSADGINTKAAQVLEGKQHG--IKMFGYSLAG-NMDLDENSYPDLAVGS-LSDSVFIYRSRPVITMTKEIKVT------PREIDLTKKTCGN-----SICLNVEACFTYK--ANPPTYSPKLRISYTLEAESVRRKQGMPSRVSFQDKKPTDQDFQSTGSLELKGQNKRA 570
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Match: itga6b (integrin alpha-6-like [Source:NCBI gene;Acc:103030335]) HSP 1 Score: 160.614 bits (405), Expect = 1.972e-39 Identity = 240/1015 (23.65%), Postives = 423/1015 (41.67%), Query Frame = 3
Query: 225 LIGAPF--DILKDSNETTGALFSCPVTKETQDCKKFVF-------SEHSNESLLGYVVDSNSHEGLIYTCAPKFLR-----SHTYVKYVEGACWEFNEMFNEVEQISNQDC-LESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------LINNNFYSRENSRSSNYLKFRNSNS----KYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVG--VIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNN--GQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLG-DSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKK-CNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVT---GGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVL--ERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLS-----------LPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIK---------VKMVANIDLKLLVT------PDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACN----VDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
L+GAP + K ++ TG L++C VT C + F SE+ + +G V S G I TCA ++ R + + + G C+ ++ E ++ + + ++ +E + +C G +A + + LV AP ++ KG+ L+ FY + Y ++ Y GFS+ GK+ +V G+P ++ + V++ K E S + + ++ GE S +GY + +D+N D +LVVGAP F N++ G ++VY N + +N + T + + +G+S+E++GDIN D D+A+GAP+E+ G G+VYIY G DS +K +Q ++G+ + +++ +G+S+ G N DLD+N YPD +GS LS + R RP++ + E V T P D KK C + I L V Y Y + Y++ I Y IE++ K R+ F NT T G ++ N + + T + + +PIE+ ++ L S KR++ L PVL + N N + G G S C L +Q + LP G+ ++ + + + LE+ N D A+ T +I ++ S + R + +I N N Q+ EC L N F N + YI + +S + + L++K + AN+ ++LL++ P ++ + G S++ E ++G ++ + + N + + L I +P + N ++LLYL++I +TG ++I C V+ L+ I R+ +++ + +D PK +D+ K ++ C +G A CV C PL + R+W T +E+F +V I
Sbjct: 6 LVGAPKAKKLSKQQSQITGGLYNCDVTTIEATCPRVNFDNDEDVRSENKSNQWMGVTVQSQGPGGKIVTCAHRYQRRLFVNTAQESRDITGRCYVLSQDLKIDESTGDEGGDWKFCEGRARGHERFGSCQQGMSATFTKDYHYLVFGAPGAFNWKGVVRVEQKNNTLLELGFYD-DGPYEVTYKTAEGLDTVAVPANSYLGFSLDSGKMVTKAGQLVVVAGAPRVNHSGAV--------VLLKKESETSPQLITEYILEGEGLASSFGYDLALLDVNGDKWQDLVVGAPQYFEKNSDIGGAIYVYINKNGNWANA-------------VRTRIDGPKDSMFGLSVESLGDINLDGFNDVAIGAPYEDGGMGSVYIYHGSDSGLKLKPAQVLKGKDL--NIKLFGYSLAG-NMDLDNNQYPDLAIGS-LSDTIAVFRARPVVNI--EKTVTMT----PKELDLNKKNCGDS------ICLQVRTCYKY--TSNSKDYSAPLRIKYSIEVESKRKKLGLPSRVTFSPHSNTDTDYESSGIVDLSKANEQ-KCVDKTIKLQDTIKDKLR-GIPIEVNVEI-LYPSARRKRDVAFSQL-----LPVLGSSQPAANEVNFVKEGCG-SDNICNSNLKLQYIFCSREPNSDNFKPLPLVGDVPVISLSDQKEIALEVTVTNQNGDD---AYETVLIGSFPGA----LSYSASRTKTPDKVVICVANQ--NGSQA-----ECELGNPFKRNSVVTFYIILGTGGISLDMNEVAVNLQLKTTSDQPPLSITKKANVIVQLLLSLSGVAKPSQLEF-TGQVKGESAMKTESEVGSQIDYEFRVINLGKPLKSFGTAFLNIQWPKSTASN------KWLLYLMKIS----STGVERIGCGRTQEVNPLSLIQESSSARLKREVGKETSSDD------------PKFSLFTDKRKS----------------KVLSCEDG-ANCVNFKC---PLQGLDSNAVIALKARLWNSTFLEDFADMNYVDI 914
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Match: ITGA6 (integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]) HSP 1 Score: 187.193 bits (474), Expect = 1.900e-48 Identity = 270/1144 (23.60%), Postives = 451/1144 (39.42%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQN-SIKYFLIGAPFD--ILKDSNETTGALFSCPVTKETQDCKKFVF-------SEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE------GACW------EFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLL----INNNFYSR----ENSRSSNYLKFRNSN----SKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNN--GQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLN------------TVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLE-RVKNNLTNTIHF-GVGCSPGS-CQPILTMQAVLSLPTEGEQY--ILHMGNVSKFKLEIQTK-----NIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNAR-----QSDNATFECMLPNDFIENVKESIYINISIEAM----------------SPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLL-IYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
++N+D +K ++ S FGFS+ + Q L+GAP + TG ++ CP T T DC++ +F +E + +G V S G + CA ++ + +V E G C+ NE +E++ S Q C S Q + L + + AP +Y KG+ N+ FY + + + +++N + Y GFSM GK N S V G+P R VV+ K +SL I+GE S +GY V DLNNDG +LVVGAP F + G V+VY N EH I L+ K + +G+++ NIGDIN+D +D+AVGAP+ DG+G V+IY G I + Q+I + +G+SI G D+D NTYPD ++GS LS + +R RP+I N++ +D + ++K C ++ + CIK+ Y +Y + Y E +M K R+ F N+ + + G G C + I P+ L + I+ ++ + SL++ PVL+ +V + + I+F GC P + CQ L ++ E E+Y + M F L Q +I+ T D DA + +L N PD + S G P + ++ + +C L N S Y+ +S + S Q L + K+KV + + + P ++ + + G S + EE +G +++ + N ++ L S + I +P EI +G++LLYL+ + G ++ CN N I Q + P + + + + + T +LP +D + DC +G+ARC + C PL+ ++ R+W T +E ++ ++D +++ + G + P+IV R P + I ++I+ SA + AT+ + KC FF+R
Sbjct: 24 TFNVDTRLAVVKEG--DSGSLFGFSVALHRQLQPIDRSVLLVGAPRAKALPNQHANRTGGVYQCPFTANTDDCQRVIFDNDADPTTESKQDQWMGVTVKSQGPGGKVLACAHRY-ETRRFVGLPEETRGMIGRCYVLSQDLRMNEQ-DEMDGGSWQFCAGRPDSHEQFGVCQQGLDAGFTRDFH--YIYFGAPGAYNWKGIAHVAQRNSTFYEQGIFDDGPYETGDERWKNEKLVPVAYNSYLGFSMDSGKSVMARNRLSFVAGAP--------RANHTGAVVVLKKDSLSSLTPEQTIYGEELASSFGYDVTLADLNNDGWLDLVVGAPQYFDRREDIGGAVYVYMN--QRGGFDEHNFIRLNGTK-----------DSMFGLAVANIGDINQDGFEDIAVGAPY--DGSGKVFIYHGGRMGINPKAS----QVIVRTVEKFGYSITG-GMDVDGNTYPDLLIGS-LSDKIALLRARPVI---TPNILVTSDKDIDI---NVKNCEND--KRICIKVKACFSYK----AKPANYNPIINLTYTFEAEMDRRKQGLGSRVSFLNRGSNSPEEYVLSGSLVLMGQGREKCTEKTMQLQENIKDKLRPIPLQLTYEINQVVKTKRQASLSLQ------------------PVLDAQVPSRMKTEINFVKEGCGPDNICQSNLILKYNYCSREENEKYKALKSMSGQQVFSLSDQKDLALEVSISNTGD------------DAHEAHLIVNLPD---AVSYGGFRKKTVPEEVQLVCVANANGSLADCELGNPLKRGQAVSFYLILSTSGITLDTSEISTALLLTTTSEQPDLNALSAKLKVVIELALTVTGFTKPSQAKFGGE-IRGESVMKTEEDVGSLIEYDFKVLNLGKSLGSLGSAFISISWPAEIP------NGKWLLYLVSVE----MVGTRETHCNPS-----GNRINELGLQKVAPEISPSNDKRRSLKLVTACARLPICAD-----------------RRVDAYDCRDGTARCYTLQC---PLTAMDSVAEIKLRARLWNSTFLE-----EYSHLD---------QLEIITRATVGISSQSPNIVMKDAR--------PDGYPVSEHICSLIM--SAHITNTATVFSLRMKCGFFKR 1027
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001557.1 (pep scaffold:Pmarinus_7.0:GL480593:314407:372761:-1 gene:ENSPMAG00000001371.1 transcript:ENSPMAT00000001557.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 148.288 bits (373), Expect = 2.147e-36 Identity = 142/477 (29.77%), Postives = 215/477 (45.07%), Query Frame = 3
Query: 222 FLIGAP---FDILKDSNETTGALFSC-----------------PVTKETQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYV---KYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNY--EYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF--TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFD-SLKKCNSNGQEMPCIKLSVSIYY 1565
L+GAP D+L ++ GA+F C P ++ C + E N+ L + N +G I CA ++ ++ YV K G C+ E C K + Y E+ +C G A LE +VL AP S+ G +I +N +R NS S R + Y G+S+ G F +P +V G+P + G+V + ++ L + G+ GS +G ++ A+DLN+DG+ +L+VGAP + + G+V VY N H L VE+ L+ N +G + +GDI+ D D+AVGAP E + GAVYIY G + I K SQ+I G+ I + +G SI G+ DLD N YPD ++G+ S V RTRP+I V E + LP S + + C GQ C+ +SV + +
Sbjct: 1 ILVGAPKADSDLLTETVHP-GAIFKCRVQPNGEQSCTEMLLGPPGSRHNHQCGRTCLEERDNQWLGVSMARQNKPDGKILACAHRW-KNAFYVREWKLPHGLCYIIPASLAPSESTHIIPCF---KEHQKKYGEEHGSCQAGIAGLFLE-DAVVLGAPGSFYWTGTVILHNLTTRANSFYSE--SERRAVGYSSYLGYSITAGH-FTHPQSTEVVGGAP---------QRANVGEVYLFRIQRGGLHIIRHFSGKKMGSYFGSALCAVDLNSDGLSDLLVGAPTHSASRDEGRVHVYVN---------HGNGDL-VEQEPLVG--LNAYNAHFGAVIAALGDIDDDGFPDVAVGAPQEEE-FGAVYIYHGSQNGITHKHSQRIFGKSIESGISMFGQSISGQ-VDLDGNGYPDVVIGAFTSDVAVLFRTRPVITV-------EASVVLPRSVNITAPLCVDGGQPTLCLNVSVCLRF 438
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005763.1 (pep scaffold:Pmarinus_7.0:GL478250:6840:43285:-1 gene:ENSPMAG00000005190.1 transcript:ENSPMAT00000005763.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 142.124 bits (357), Expect = 2.274e-34 Identity = 137/509 (26.92%), Postives = 225/509 (44.20%), Query Frame = 3
Query: 105 FSYNIDL-NSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSC-------------PVTKETQDCKKFVFSEHSNESLLGYVV--DSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDC-LESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNS---KYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQ--DLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFD-SLKKCNSNGQEMPCIKLSV 1553
+YN+D+ + I+ +FFGFS + + + LIGAP + E +GA+F C P+ K T + + E + LG + ++ E + CA + + + G C+ C + ++ + + ++ +C G A S + +VL P S+ G ++ +N SS + F ++ K Y G+S++ G IF N +V G+P Q G+V + L+E L+ G+ GS +G + A+DL+ DG+ +L+VGAP + G+V V+ N Q N+ VE++ LL+ N +G + +GDIN D + D+A+GAP E+D GAVYIY G I SQ+I G+ ++ +L +G SI G D+D N YPD VG+ S V R + ++ V A + LP + + S C Q + CI + V
Sbjct: 28 LAYNLDVAGAAPIRGA---KGTFFGFS--VLQHAYENDTWVLIGAPQ--AQSGAERSGAVFKCHEDGAGGYSCSELPIDKRTGNVCGTLCRETRADQWLGVSLAREAGGGESKVMACAHRRANVNPDDIFPHGICFLIPPDLKPDAVTHTSPCSIGAVDAHDEMRQHASCQAGMAASSATQNFMVLGGPGSFNWAGTVMLHNV-------SSGFTHFSTPDTVVTKDSYLGYSVSAG-IFYNRTSLGVVAGAP---------RQDNVGKVYLLTLVEGELQITWQSSGKQLGSYFGSATCAVDLDADGLADLLVGAPQHSETRDEGRVHVFMN--AGQGNL--------VEQKSLLSGANAY-NAHFGQVIVALGDINDDRFEEPDVAIGAPHEDDLRGAVYIYNGGPSGISHSFSQRILGRSVNGELSMFGHSISGV-IDMDRNGYPDVTVGAFNSDAAVVFRAKAVVTVRAH-------VSLPSTVNASSSVCPGTHQPVTCIIIRV 493
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Match: ITGA6 (integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]) HSP 1 Score: 119.013 bits (297), Expect = 2.025e-27 Identity = 126/514 (24.51%), Postives = 223/514 (43.39%), Query Frame = 3
Query: 276 ALFSCPVTKETQDCKKFVFSEHSN-------ESLLGYVVDSNSHEGLIYTCAP-----KFLRSHTYVKYVEGACWEFNEMFN-EVEQISNQDCLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL---------LINNNFYSRENSR------SSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKL--IENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF-----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTG 1706
+++CP+T++ DC + F +H + +G V S G + CA KF+ + ++ G C+ + + + S + ++Y Y C G AA + + L +P ++ +G L+ + +++ ++ + NS ++ FS+ V S+V G+P + G V++ + NSL ++ GE S YGY+V DLN DG +L+VGAP+ + G V+VY N + E K KR+ L + + +G+++ IGD++ D QD+AVGAPFE +G VYIY G +I Q+ G+G+S+ G D+D N YPD +VGS LS VV R+R +I +++ + D+ + S+K C + ++ C+++ Y+ P+Y+ + T+ Y + + + S R++ T TG
Sbjct: 21 GIYACPITQQPGDCSRLTFDDHVDPKEESKENQWMGVTVRSQGPGGKVLACAHRYERRKFVGNSEEIRSPVGRCYVLGQALGLDQDDHSEGGGWHACSDRGESYALYGFCQQGTAAGFTRDYHYLYFGSPGAHYWRGATHLECHSSALVPHKLQEVGSAQRLGEQVGADAVVHVQHNSTFR---FSVDVANNVARRGEPSVVAGAPRAAH---------MGAVLLLAVNYSHNSLVPEVMLRGEGLASAYGYAVCLADLNGDGWMDLLVGAPYFFDQSKKSVGGAVYVYLND--NDGGGERK-------KRVRL---EGTAGSGFGLTIAAIGDVDLDGFQDVAVGAPFEE--SGRVYIYSGGPSGVITKP----AQVWHASQPGFGYSLSG-GLDVDGNLYPDLLVGS-LSDQVVLFRSRTVITADV-HLLTDGDIDM-----SVKNCEN--RQSTCVRVLACFSYW----ARPPTYSPAITLHYSLNAEEDRRQQGLSSRVHLTAIAGTETG 490
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Match: itga8 (integrin, alpha 8 [Source:ZFIN;Acc:ZDB-GENE-080220-48]) HSP 1 Score: 115.546 bits (288), Expect = 2.874e-26 Identity = 85/254 (33.46%), Postives = 132/254 (51.97%), Query Frame = 3
Query: 711 SNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFEN-DGTGAVYIYLGDSHQIIKL-SQKIEGQMISPDLRG-YGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVA 1463
+N+ Y G+S+AVG+ F +V+ V G P S FG V+I L + + + GE S +GY+V D+NNDG+D+L+VGAP Q + E+ + + + PL + L+ G+YG ++ +GD+++D D+AVG PF DGTG V++Y G ++ + SQ + G+ S L +GF++ G DLDSN YPD IVG+ + R RP++ V AE V+
Sbjct: 27 ANNDDAYMGYSVAVGE-FTGDSVQEFVTGVPKGSS--------TFGYVLI--LNTTDMSTLMNVTGEQLASYFGYTVAVTDVNNDGLDDLLVGAPLYMERGSQGRLE---ELGRVYLYLQQAPLSLGAAQTLSGRDVY--GRYGSAITPVGDLDQDGYNDVAVGMPFGGEDGTGVVFVYNGRDTGLMAIPSQTLRGRWASQGLPASFGFALRG-GTDLDSNGYPDLIVGAFGVDKAIVYRARPVVTVSAELTVS 263
BLAST of Alpha-int-3 vs. Ensembl Nematostella
Match: EDO48984 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH6]) HSP 1 Score: 123.25 bits (308), Expect = 2.750e-28 Identity = 100/274 (36.50%), Postives = 147/274 (53.65%), Query Frame = 3
Query: 918 GSGYGYSVLAMDLNNDGMDELVVGAPF--TNN--NNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISP-----DLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQL-PYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSK-------TIDYEIELDMPFI---KTSSSKRLYF 1679
GSG+G+SV +D+N DG ++V+GAPF T N N G+VFVY N + KT R L S+ + +G ++ N+GD+++D +D AVGAP+E +GTG VYI+ G + SQK GQ+I P DL+ +G SI GK D+D N YPD ++G+ S VV +R+RPII + TD+ + P F+S K S + I+ +V I D+ C SY+ + +ID IE D+ + +TS R+ F
Sbjct: 323 GSGFGFSVAGVDVNGDGWTDVVIGAPFYSTKNSPNEGRVFVYTN---NGDGTFSKT-------RELAPSIAR-KGAYFGHAVANLGDLDQDGYEDFAVGAPYE-EGTGVVYIFNGSETGV---SQKA-GQLIKPTDINQDLKTFGSSIAGK-LDMDGNGYPDLLIGAYTSDSVVLLRSRPIIDI-------NTDVNITPNPFNSRNKTCSKTFKGKLIQ-TVCI-----DIEICLSYSERRNRTHDKLSIDLNIEADVEYTRNSRTSKQSRVVF 566 HSP 2 Score: 58.9214 bits (141), Expect = 1.308e-8 Identity = 72/323 (22.29%), Postives = 139/323 (43.03%), Query Frame = 3
Query: 2349 HLRPIVLKIKVKMVANIDLKLLVTPDNYQYR-EDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLK-KVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFL---KYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVI--YAIIIAVSAGVILLATIVIILYKCNFFRRQ 3296
L+ ++++ V +V+ DL+L + Q + G S++ E++IG +++ T +N + + ++++I +P+E T+G++LLYL+ + +GN + D N + ++K + P + Q + T T V + IK + + E + V +DC G+ARC P+ C + ++ E++ RIW TLIE++ K V + V + L N + V PP D + + I +AV ++ L +++IL+K FF+R+
Sbjct: 966 QLKDNLIELNVTIVSQADLELSGSFKQEQVSYGGEVKGESAMRVEDEIGNEVRHTYIAQNKGPD-FVPEAEVVIQWPFEA------TNGKHLLYLMDVE----ISGNAECTFAPDQPNLLGLIVKPKSS----PARNVTSRQSSSESTRTTRVRRAVEEETSIK-----TKRATADERGSSVKLDCETGTARCTPIRCLIKRFAK-GNEVSFVVRSRIWAATLIEDYYNTDKSSEVTVVSRASLRAAVTFVRELNKENNNAE------------VKTQFNPDFPPRKSDKLASWVIPVAVVGAILALVIVILILWKLGFFKRK 1255
BLAST of Alpha-int-3 vs. Ensembl Nematostella
Match: EDO49372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG71]) HSP 1 Score: 107.071 bits (266), Expect = 2.176e-23 Identity = 139/590 (23.56%), Postives = 241/590 (40.85%), Query Frame = 3
Query: 51 MEFINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAP-------FDILKDSNETTGALFSCPVTKETQ------DCKKFVFSEHSNESL---------LGYVVDSNSHEGLIYTCAPKFL-------RSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRN---CLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTG----FSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFT--NNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFEN-DGTGAVYIYLGDSHQI-IKLSQKIEG-QMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNT 1697
M + I L V + +N+D++ P + + N +FGF++ + + + K+ L+GAP F +E G +F C K + D ++ + + E + LG + S G CAP++ R + V G C+ + + + + C Y Y C G + L A GKG++ ++ R +S + R+S+ K Y G ++M G+ F+ + ++ SP + D R ++ VV + I+ S + + GS +G+S+ A+DLNNDG+ +L+VGAP + + G+V+VY N NG I++ + VGAP+ D GAVYIY G I K Q++ M P L+ +G+S+ G D+D N+YPD VG+ S V +R+RPI+ V + ++ + L + +L C G + C+ V + Y + P + +D+ + LD +T +R++F+ K T
Sbjct: 1 MGAVKCILAVLLAVLHVVICFNVDISEPIVFRSQAKN-DYFGFTVALHSYGDD--KWLLVGAPLANQTAPFGSRFKIHERYGGVFKCRPRKNSACETIPIDTTDPLYQDFNGEQIDIEEKAGQWLGASLFSTGQNGKAVACAPRYTFRGNFINRPEKRPRNVIGRCFLIRDDLRGLHKRVSP-CYHGSNGRELMYGYGQDGMCQAGFSTVITNDDTLGFGAVGVGYGKGMI--GAYFDRSDS----TVFARSSDLKVGYFGDVFGYTMTAGR-FKRSGKEQLIGSSP---RADDIRGRVMAFDVVGDEQIKVSFT-LPLPPDNQPGSAFGFSMCAVDLNNDGLSDLLVGAPRYSYDKDEGRVYVYVN------------------------------NGLVSITIPKY----------VVVGAPYGGPDRRGAVYIYHGTKDGIDTKYRQRVTASDMNDPALKTFGYSLTG-GLDMDDNSYPDVAVGAYSSDRAVLLRSRPIVDVVGKIELSTNRIILESNQTNL--CTLQGNQHKCLTARVCLKYKH----KVP-VSQGVELDFSLALDQDR-RTIELRRMFFDPKNTT 526
BLAST of Alpha-int-3 vs. Ensembl Nematostella
Match: EDO37905 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SED1]) HSP 1 Score: 50.447 bits (119), Expect = 4.517e-6 Identity = 41/110 (37.27%), Postives = 53/110 (48.18%), Query Frame = 3
Query: 1122 LSNGQYGISLENIGDINKDFIQDLAVGAPFENDG---------TGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNE-----------DLDSNTYPDFIVGS 1391
+ NG++G L + D+NKD I DLAV AP E G TGAVY+Y G L + I I PDL +I GK + D+DS+ Y D I+GS
Sbjct: 460 VPNGRFGYDLA-VSDLNKDGIDDLAVSAPSEGKGRLRADNLQYTGAVYVYYG------VLGKGIP---IKPDL-----TIIGKGQYYNLGTKLLGADIDSDGYRDLIIGS 554
BLAST of Alpha-int-3 vs. Ensembl Medaka
Match: itga3b (integrin subunit alpha 3 [Source:NCBI gene;Acc:101157734]) HSP 1 Score: 200.29 bits (508), Expect = 6.886e-52 Identity = 269/1109 (24.26%), Postives = 486/1109 (43.82%), Query Frame = 3
Query: 111 YNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFL-IGAPFDI---LKDSNETTGALFSCPVTKETQDCKK--FVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTA-------------PYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISP-DLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEI-TMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGC-SPGSCQPILTMQAVLSLPTEGE----------QYILHMGNVSKFKLEI---QTKNIATTDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLR--PIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTE-TDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID-IPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
+N+D P IK S FGFS+ + S ++ L +GAP + LKD NET GA+++CP++ DC + V S+E + G + ++ + H Y K V G E M + SN L++ Q Y C G ++S + L ++ Y+++G +I N +NS +N F +++ Y G+S+ + + ++V G+P ++DS G V++G++ + + + +I GE GS +G S+ A DLNND ++L+VGAPF N G V+++ N S N+ K +K + +G ++ IGD+N+D QD AVGAPF+ TG VYI++G I K SQ IEG+ + + + +G+SI G D+D N+YPD +VGS L + +R RP+I + +N E P+ D N PCI +V + + + + S +DY +E + ++ +R+YF++ ++ S S S+ ++ +I +N+F + ++ + +S+N+S + + L +L ++PVL + + + IHF C + C L ++A E QY +M + K+++ ++ D ++ + I L Y + + N + + G++ + +PL A + + + I+ I + + +S Q L+ + + I+ ++ + K L + +++G S++ +G ++FT ++ N Q L + L + F W P E +G++LLYL ++ + G + C+ L N N+ + ED +K T P+ + ++ LPK + L+DC +G+A+CV C L +S+ + EI ++ R+W T++E++ V + W+ + ++ +K VV + + P L ++ II AV AGV+LLA I+ IL+KC FF+R
Sbjct: 22 FNLDQRFPVIKEGETKG-SLFGFSVALHEQTVGSRQHLLLVGAPKEKANGLKDVNET-GAVYACPISTTFDDCSRMDLVTQPSSSEMVEGMWLGVTVASQKGHSAGRVLMCGHRYAKIVTGGTEEQRRMIGKCYVRSNDLTLDATDF-WQTDSYEVCNPGYDMESEGQCNLGISGGIGYTDVYLGAVGSYTWQGNVHVIWRN-PEPDNSWEANGKAFGELDNRNIYMGYSVLEEQKLLKQDQYTVVTGAP---RFDSR------GSVILGEMSQAKISLMQLIPGEQVGSYFGSSLAAADLNNDDWNDLIVGAPFYFERQNQIGGAVYIFMNENGSFQNVSTKV-------------LKGPAYSGFGFAVAAIGDVNQDGFQDFAVGAPFQE--TGRVYIWMGSKKGISDKYSQMIEGKSVGDGNFQSFGYSIDG-GMDMDGNSYPDMVVGS-LDDRIALIRARPVIHL-TKNFTVE-----PFIVDP----NQCTDAKPCISATVCMSFTLSNGN--KDFKKSIVVDYTMEAGVGELR----RRVYFQDD------------RSTFSGSLSLSSSKSICETLNVFVKTPVRDKLDAVHFSINMSLPEQTSKARRSLQNLDSFPVLSQDQKLIHKAEIHFQKECGTDNKCSSNLQLKAQFVDEKETPYPRRDGMQIFQYNRNMRIIIGLKVDVTNLKSPGKVAEDAHQTMLSVTIPNTLKYAGVRPPTYQCNAN---DANDGVLCEIGNPLKAEEM--TSLRLLFETSDIDLNTNLIECQLLLSTVSEQSDLKREAVGILIESTILPSFSAKALSVGTKFG---GTVMGESAMVNTSDVGSLVEFTFNVDMNEQLLGDLGT-LAVEFKW-----PFEVANGKWLLYLTKV----VVKGRSETECDAGGLVNSLNLSLSHSRPQRTKRQADEDDANEKFQSQTTEPQ---AASKLLTLPK----------KESYLLDCTQGTAKCVTFSCPLLNMSK-TAEIYVR--SRLWNSTMLEDYSNALTVTVKGQATLWLMAKKPTIKMETQTIEFK-----------VVIEPEEGVETPYELP-LWIIISAVVAGVLLLAIIIAILWKCGFFQR 1026
BLAST of Alpha-int-3 vs. Ensembl Medaka
Match: itga3b (integrin subunit alpha 3 [Source:NCBI gene;Acc:101157734]) HSP 1 Score: 196.052 bits (497), Expect = 1.664e-50 Identity = 268/1110 (24.14%), Postives = 484/1110 (43.60%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFL-IGAPFDI---LKDSNETTGALFSCPVTKETQDCKK--FVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTA-------------PYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPF----TNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII-KLSQKIEGQMISP-DLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEI-TMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNT-IHFGVGC-SPGSCQPILTMQAVLSLPTEGE----------QYILHMGNVSKFKLEI---QTKNIATTDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLR--PIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTE-TDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYID-IPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRR 3293
+N+D P IK S FGFS+ + S ++ L +GAP + LKD NET GA+++CP++ DC + V S+E + G + ++ + H Y K V G E M + SN L++ Q Y C G ++S + L ++ Y+++G +I N +NS +N F +++ Y G+S+ + + ++V G+P ++DS G V++G++ + + + +I GE GS +G S+ A DLNND ++L+VGAPF N G V+++ N S N+ K +K + +G ++ IGD+N+D QD AVGAPF+ TG VYI++G I K SQ IEG+ + + + +G+SI G D+D N+YPD +VGS L + +R RP+I + +N E P+ D N PCI +V + + + + S +DY +E + ++ +R+YF++ ++ S S S+ ++ +I +N+F + ++ + +S+N+S + + L +L ++PVL + + + IHF C + C L ++A E QY +M + K+++ ++ D ++ + I L Y + + N + + G++ + +PL A + + + I+ I + + +S Q L+ + + I+ ++ + K L + +++G S++ +G ++FT ++ N Q L + L + F W P E +G++LLYL ++ + G + C+ L N N+ + ED +K T P+ + ++ LPK L+DC +G+A+CV C L +S+ + EI ++ R+W T++E++ V + W+ + ++ +K VV + + P L ++ II AV AGV+LLA I+ IL+K FF+R
Sbjct: 21 GFNLDQRFPVIKEGETKG-SLFGFSVALHEQTVGSRQHLLLVGAPKEKANGLKDVNET-GAVYACPISTTFDDCSRMDLVTQPSSSEMVEGMWLGVTVASQKGHSAGRVLMCGHRYAKIVTGGTEEQRRMIGKCYVRSNDLTLDATDF-WQTDSYEVCNPGYDMESEGQCNLGISGGIGYTDVYLGAVGSYTWQGNVHVIWRN-PEPDNSWEANGKAFGELDNRNIYMGYSVLEEQKLLKQDQYTVVTGAP---RFDSR------GSVILGEMSQAKISLMQLIPGEQVGSYFGSSLAAADLNNDDWNDLIVGAPFYFERQNQIGGAVYIFMNENGSFQNVSTKV-------------LKGPAYSGFGFAVAAIGDVNQDGFQDFAVGAPFQE--TGRVYIWMGSKKGISDKYSQMIEGKSVGDGNFQSFGYSIDG-GMDMDGNSYPDMVVGS-LDDRIALIRARPVIHL-TKNFTVE-----PFIVDP----NQCTDAKPCISATVCMSFTLSNGNK--DFKKSIVVDYTMEAGVGELR----RRVYFQDD------------RSTFSGSLSLSSSKSICETLNVFVKTPVRDKLDAVHFSINMSLPEQTSKARRSLQNLDSFPVLSQDQKLIHKAEIHFQKECGTDNKCSSNLQLKAQFVDEKETPYPRRDGMQIFQYNRNMRIIIGLKVDVTNLKSPGKVAEDAHQTMLSVTIPNTLKYAGVRPPTYQCNAN---DANDGVLCEIGNPLKAEEM--TSLRLLFETSDIDLNTNLIECQLLLSTVSEQSDLKREAVGILIESTILPSFSAKALSVGTKFG---GTVMGESAMVNTSDVGSLVEFTFNVDMNEQLLGDLGT-LAVEFKW-----PFEVANGKWLLYLTKV----VVKGRSETECDAGGLVNSLNLSLSHSRPQRTKRQADEDDANEKFQSQTTEPQ---AASKLLTLPKKES----------YLLDCTQGTAKCVTFSCPLLNMSK-TAEIYVR--SRLWNSTMLEDYSNALTVTVKGQATLWLMAKKPTIKMETQTIEFK-----------VVIEPEEGVETPYELP-LWIIISAVVAGVLLLAIIIAILWKLGFFKR 1026
BLAST of Alpha-int-3 vs. Ensembl Medaka
Match: itga6b (integrin alpha-6 [Source:NCBI gene;Acc:101167322]) HSP 1 Score: 186.422 bits (472), Expect = 1.739e-47 Identity = 248/1053 (23.55%), Postives = 416/1053 (39.51%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIK-YFLIGAP--FDILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQD--CLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL--LINNNF------------YSRENSRSSN-YLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNN--NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII--KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCP-SYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNI-SLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSP-GSCQPILTMQAVLSLPTEGEQY-----------ILHMGNVSKFKLEIQTKNIATTDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMS---------------PQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETD-GQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
++N+D ++ K + S FGFSL + K L+GAP + ++ TG L+SC + ++ C + +F E +G V S G I TCA ++ R + +E G C+ ++ + + SN+D S + +E + +C G +A + + AP +Y KG+ L NF Y + + N L +NS Y GFS+ G+ N ++V G+P + + +K G L+E EY + GE S +GY + +DLN DG +++VVGAP F + G +++Y N N + T T + + +G+++EN+GDIN+D D AVGAP++++G G VYIY G + II K Q + GQ + L +G+S+ G N DLD NTYPD VGS LS V R RP++ + E + + L + K C + C+ ++ Y T P SYA + T+ Y +E D K R F S T + + T + N+ + +P+++ S+++ + +R S PVL+ +K GC C+ L M L T E ++ + N LE+ N D ++A T I LTY ++ S+ + V++ +R +C L N F+ + + YI S +S ++ + + KV ++ + L V P Y + + G +++ E IG + + N + + L W P ET+ G++LLYL+ I + + ++ LN + ++R + KV V + +L + EI + C G A+CV + C LG L G + F R+W T +E++ + V +
Sbjct: 20 AFNLDTDNVLRKDG--DPGSLFGFSLAMHRQLSPVDKTMLLVGAPRAAALSNQKSKVTGGLYSCDMASSSKSCTRIIFDNDEDVKKESKENQWMGVSVSSQGPGGKIVTCAHRYQRRNNVRTNLESRDIIGRCYVLSQDLS-IRADSNEDGGSWHFCDSRLRGHEMFGSCQQGLSATFDDDYHYFIFGAPGAYNWKGIVRLEQKNFSLVEMGIFDDGPYELGDEKQKNPNLVPAPANS---YLGFSLDSGRSLTNKGQLTVVAGAP-RANHSGAVVLLKKGLTTSNILLE---EYT--LEGEGLASSFGYDLAVLDLNKDGWEDIVVGAPQFFVKDGEIGGAIYIYIN---KNGNWDQVTP----------TRINGPKDSMFGLAVENLGDINQDGYHDFAVGAPYKDNGVGQVYIYCGSATGIISEKDPQVLSGQPLGVKL--FGYSLAG-NMDLDKNTYPDLAVGS-LSDSVFVYRARPVVNIKKEVTFSPNQINL-----ADKSCG----KAFCMDVTACFTY-----TANPKSYAPTLTVAYTLEADADLRKKGLKPRAIFTESSELDGNAQSTGTITMDKQGKEQCVTRKLAIQENIRDKLQGIPVDV----SVSIQDAKRRRRQSSTAKLT---PVLDEIKPTRATVEFLKEGCGQDNECESNLKMNYRFGLRTTTEDDFTELNQEDGLPVISLSNQKDIALEVTVTNQKGDDAHEASLTAIFPSSLTYSTYRV-----------SSQESPVTCVSNKEGSRA------DCELGNPFMRDAETKFYIFFSTAGISFNISEVEITLMLNTTSKQSKSTVKARAKVAIMLQLSLLGQVNPSQVHYTGE-IKGETAMITESDIGSGITHQFRVINLGKRLTDFGTATL-EIDW-----PKETEQGKWLLYLMNINSMGVDQIKCTPSAEINPLNKKPDTARSR-----------RAAESTKVDVKGTISRLIDTKKEI-------------------TLSCNNG-AKCVKIKCPLGGL---DGNAVITFSSRLWNTTFLEDYSDFHHVEV 964
BLAST of Alpha-int-3 vs. Ensembl Medaka
Match: itga6b (integrin alpha-6 [Source:NCBI gene;Acc:101167322]) HSP 1 Score: 186.422 bits (472), Expect = 1.896e-47 Identity = 248/1053 (23.55%), Postives = 416/1053 (39.51%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIK-YFLIGAP--FDILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQD--CLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL--LINNNF------------YSRENSRSSN-YLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNN--NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII--KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCP-SYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNI-SLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSP-GSCQPILTMQAVLSLPTEGEQY-----------ILHMGNVSKFKLEIQTKNIATTDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMS---------------PQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETD-GQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
++N+D ++ K + S FGFSL + K L+GAP + ++ TG L+SC + ++ C + +F E +G V S G I TCA ++ R + +E G C+ ++ + + SN+D S + +E + +C G +A + + AP +Y KG+ L NF Y + + N L +NS Y GFS+ G+ N ++V G+P + + +K G L+E EY + GE S +GY + +DLN DG +++VVGAP F + G +++Y N N + T T + + +G+++EN+GDIN+D D AVGAP++++G G VYIY G + II K Q + GQ + L +G+S+ G N DLD NTYPD VGS LS V R RP++ + E + + L + K C + C+ ++ Y T P SYA + T+ Y +E D K R F S T + + T + N+ + +P+++ S+++ + +R S PVL+ +K GC C+ L M L T E ++ + N LE+ N D ++A T I LTY ++ S+ + V++ +R +C L N F+ + + YI S +S ++ + + KV ++ + L V P Y + + G +++ E IG + + N + + L W P ET+ G++LLYL+ I + + ++ LN + ++R + KV V + +L + EI + C G A+CV + C LG L G + F R+W T +E++ + V +
Sbjct: 20 AFNLDTDNVLRKDG--DPGSLFGFSLAMHRQLSPVDKTMLLVGAPRAAALSNQKSKVTGGLYSCDMASSSKSCTRIIFDNDEDVKKESKENQWMGVSVSSQGPGGKIVTCAHRYQRRNNVRTNLESRDIIGRCYVLSQDLS-IRADSNEDGGSWHFCDSRLRGHEMFGSCQQGLSATFDDDYHYFIFGAPGAYNWKGIVRLEQKNFSLVEMGIFDDGPYELGDEKQKNPNLVPAPANS---YLGFSLDSGRSLTNKGQLTVVAGAP-RANHSGAVVLLKKGLTTSNILLE---EYT--LEGEGLASSFGYDLAVLDLNKDGWEDIVVGAPQFFVKDGEIGGAIYIYIN---KNGNWDQVTP----------TRINGPKDSMFGLAVENLGDINQDGYHDFAVGAPYKDNGVGQVYIYCGSATGIISEKDPQVLSGQPLGVKL--FGYSLAG-NMDLDKNTYPDLAVGS-LSDSVFVYRARPVVNIKKEVTFSPNQINL-----ADKSCG----KAFCMDVTACFTY-----TANPKSYAPTLTVAYTLEADADLRKKGLKPRAIFTESSELDGNAQSTGTITMDKQGKEQCVTRKLAIQENIRDKLQGIPVDV----SVSIQDAKRRRRQSSTAKLT---PVLDEIKPTRATVEFLKEGCGQDNECESNLKMNYRFGLRTTTEDDFTELNQEDGLPVISLSNQKDIALEVTVTNQKGDDAHEASLTAIFPSSLTYSTYRV-----------SSQESPVTCVSNKEGSRA------DCELGNPFMRDAETKFYIFFSTAGISFNISEVEITLMLNTTSKQSKSTVKARAKVAIMLQLSLLGQVNPSQVHYTGE-IKGETAMITESDIGSGITHQFRVINLGKRLTDFGTATL-EIDW-----PKETEQGKWLLYLMNINSMGVDQIKCTPSAEINPLNKKPDTARSR-----------RAAESTKVDVKGTISRLIDTKKEI-------------------TLSCNNG-AKCVKIKCPLGGL---DGNAVITFSSRLWNTTFLEDYSDFHHVEV 964
BLAST of Alpha-int-3 vs. Ensembl Medaka
Match: itga6b (integrin alpha-6 [Source:NCBI gene;Acc:101167322]) HSP 1 Score: 186.422 bits (472), Expect = 2.101e-47 Identity = 248/1053 (23.55%), Postives = 416/1053 (39.51%), Query Frame = 3
Query: 108 SYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIK-YFLIGAP--FDILKDSNETTGALFSCPVTKETQDCKKFVFS-------EHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVE-----GACWEFNEMFNEVEQISNQD--CLESIKSESQNYE-YRNCLTG-AALKSLERKQLVLTAPYSYEGKGL--LINNNF------------YSRENSRSSN-YLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAP--FTNNN--NGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQII--KLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCP-SYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNI-SLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSP-GSCQPILTMQAVLSLPTEGEQY-----------ILHMGNVSKFKLEIQTKNIATTDDNKAFRTYII---LTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMS---------------PQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETD-GQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYI 3047
++N+D ++ K + S FGFSL + K L+GAP + ++ TG L+SC + ++ C + +F E +G V S G I TCA ++ R + +E G C+ ++ + + SN+D S + +E + +C G +A + + AP +Y KG+ L NF Y + + N L +NS Y GFS+ G+ N ++V G+P + + +K G L+E EY + GE S +GY + +DLN DG +++VVGAP F + G +++Y N N + T T + + +G+++EN+GDIN+D D AVGAP++++G G VYIY G + II K Q + GQ + L +G+S+ G N DLD NTYPD VGS LS V R RP++ + E + + L + K C + C+ ++ Y T P SYA + T+ Y +E D K R F S T + + T + N+ + +P+++ S+++ + +R S PVL+ +K GC C+ L M L T E ++ + N LE+ N D ++A T I LTY ++ S+ + V++ +R +C L N F+ + + YI S +S ++ + + KV ++ + L V P Y + + G +++ E IG + + N + + L W P ET+ G++LLYL+ I + + ++ LN + ++R + KV V + +L + EI + C G A+CV + C LG L G + F R+W T +E++ + V +
Sbjct: 20 AFNLDTDNVLRKDG--DPGSLFGFSLAMHRQLSPVDKTMLLVGAPRAAALSNQKSKVTGGLYSCDMASSSKSCTRIIFDNDEDVKKESKENQWMGVSVSSQGPGGKIVTCAHRYQRRNNVRTNLESRDIIGRCYVLSQDLS-IRADSNEDGGSWHFCDSRLRGHEMFGSCQQGLSATFDDDYHYFIFGAPGAYNWKGIVRLEQKNFSLVEMGIFDDGPYELGDEKQKNPNLVPAPANS---YLGFSLDSGRSLTNKGQLTVVAGAP-RANHSGAVVLLKKGLTTSNILLE---EYT--LEGEGLASSFGYDLAVLDLNKDGWEDIVVGAPQFFVKDGEIGGAIYIYIN---KNGNWDQVTP----------TRINGPKDSMFGLAVENLGDINQDGYHDFAVGAPYKDNGVGQVYIYCGSATGIISEKDPQVLSGQPLGVKL--FGYSLAG-NMDLDKNTYPDLAVGS-LSDSVFVYRARPVVNIKKEVTFSPNQINL-----ADKSCG----KAFCMDVTACFTY-----TANPKSYAPTLTVAYTLEADADLRKKGLKPRAIFTESSELDGNAQSTGTITMDKQGKEQCVTRKLAIQENIRDKLQGIPVDV----SVSIQDAKRRRRQSSTAKLT---PVLDEIKPTRATVEFLKEGCGQDNECESNLKMNYRFGLRTTTEDDFTELNQEDGLPVISLSNQKDIALEVTVTNQKGDDAHEASLTAIFPSSLTYSTYRV-----------SSQESPVTCVSNKEGSRA------DCELGNPFMRDAETKFYIFFSTAGISFNISEVEITLMLNTTSKQSKSTVKARAKVAIMLQLSLLGQVNPSQVHYTGE-IKGETAMITESDIGSGITHQFRVINLGKRLTDFGTATL-EIDW-----PKETEQGKWLLYLMNINSMGVDQIKCTPSAEINPLNKKPDTARSR-----------RAAESTKVDVKGTISRLIDTKKEI-------------------TLSCNNG-AKCVKIKCPLGGL---DGNAVITFSSRLWNTTFLEDYSDFHHVEV 964
BLAST of Alpha-int-3 vs. Planmine SMEST
Match: SMESG000034289.1 (SMESG000034289.1) HSP 1 Score: 2170.97 bits (5624), Expect = 0.000e+0 Identity = 1074/1090 (98.53%), Postives = 1078/1090 (98.90%), Query Frame = 3
Query: 51 MEFINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK 3320
MEFINFIFLFLFHVP LYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVF+EHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFN+MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVA TDMQLPYSFDSLKKCNSNGQEMPCIKLSVSI+YYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRN LSDDLADLSNYPVLERVKNNLTN IHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKF+IALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK
Sbjct: 1 MEFINFIFLFLFHVPALYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFTEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNDMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAATDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIHYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNFLSDDLADLSNYPVLERVKNNLTNKIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFSIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK--------KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNFFRRQNVGKRRWK 1082
BLAST of Alpha-int-3 vs. Planmine SMEST
Match: SMESG000034289.1 (SMESG000034289.1) HSP 1 Score: 2134.38 bits (5529), Expect = 0.000e+0 Identity = 1060/1078 (98.33%), Postives = 1065/1078 (98.79%), Query Frame = 3
Query: 51 MEFINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFSEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNXXXXXXXXXXNYPVLERVKNNLTNTIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFTIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYKKLPDIVSHKVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKCNF 3284
MEFINFIFLFLFHVP LYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVF+EHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFN+MFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVA TDMQLPYSFDSLKKCNSNGQEMPCIKLSVSI+YYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRN LSDDLADLSNYPVLERVKNNLTN IHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKF+IALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYK +F
Sbjct: 1 MEFINFIFLFLFHVPALYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKDSNETTGALFSCPVTKETQDCKKFVFTEHSNESLLGYVVDSNSHEGLIYTCAPKFLRSHTYVKYVEGACWEFNDMFNEVEQISNQDCLESIKSESQNYEYRNCLTGAALKSLERKQLVLTAPYSYEGKGLLINNNFYSRENSRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKSIVLGSPGISQYDSTRTQIKFGQVVIGKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPFENDGTGAVYIYLGDSHQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAATDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIHYYYPDLTTCPSYASSKTIDYEIELDMPFIKTSSSKRLYFENKLNTVTGGGSINCKTPNSKSNSIINTFNILFPVNLFFNISLPIEITMKWSLNVSEVPKRNFLSDDLADLSNYPVLERVKNNLTNKIHFGVGCSPGSCQPILTMQAVLSLPTEGEQYILHMGNVSKFKLEIQTKNIATTDDNKAFRTYIILTYDAKKINLFSNNPDRKTSTSSGLIYAVNSPLNARQSDNATFECMLPNDFIENVKESIYINISIEAMSPQRHLRPIVLKIKVKMVANIDLKLLVTPDNYQYREDSLLGFSSITGEEKIGPKMKFSIALENNVQNSVILSSKLLIYFPWEISGNPTETDGQYLLYLLRIPKFSITTGNKKIACNVDILNNITNVIKTRIYQDIIPISKLEDVQLKKVTVPTNVPKLPNISDEIKFLPKDSDSGSISEWENIVLIDCFEGSARCVPVVCDLGPLSRQSGEITLQFDIRIWIHTLIENFLKYKFVYIDIPVFWVPLVDYDVVLQVPGGNYK--------KVRVVAANLQKPKPPASLDVIYAIIIAVSAGVILLATIVIILYKVSF 1070
BLAST of Alpha-int-3 vs. Planmine SMEST
Match: SMESG000022733.1 (SMESG000022733.1) HSP 1 Score: 89.3521 bits (220), Expect = 1.221e-17 Identity = 151/580 (26.03%), Postives = 252/580 (43.45%), Query Frame = 3
Query: 117 IDLNSPYIKSNFINNKSFFGFSLNIFTSKQNSIKYFLIGAPFDILKD----SNETTGALFSCPVTKETQDCKKF-VFSEHSNESLLGYV--------VDSNSHEGLIYTCAPKFLRSHTY-VKYVE------GACWEFNEMFNEVEQISNQDCLESIKSESQNYEYRNCLTG----AALKSLERKQLVLTAPYSYEGKGLLINNNFYSREN------SRSSNYLKFRNSNSKYQYTGFSMAVGKIFRNPNVKS-----IVLGSPGISQYDSTRTQIKFGQVVI--GKLIENSLEYVGVIFGEVFGSGYGYSVLAMDLNNDGMDELVVGAPFTNNNN---------GQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAP-FENDGTGAVYIYLGDSH---QIIKLSQKIEGQMISPD------------LRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQLPYSFDSLKKCNSNGQEMPCIKLSVSIYYYYPDLTTCPSYASSKT------IDYEIELDMPFIK 1652
+ L+ Y+ SN S+FG+S++ F ++ + Y L+GAP D + D N TG ++ ++ DC K + SE S GY N G+ C P+FL +Y V E G C + + + IS C S+ E CL+G + E+ ++ L P S+ +G + NF S + LK R N Y + G R+P + S +V SP + S + G V++ KL + + Y+ + G + GS +G S+ D N D + +++VGAPF ++ G +++++ Q + + K + L +++ G++G+S+ N+GDI+ D I D AVG P ND TG+VYIYLG S Q+I+ + + +++P + +G+S+ GK D+D N+ PD I+G S +V +R++ +I + EN V LP S S++ N + PC S Y ++S+ ID + +L+ PF K
Sbjct: 34 VGLSKLYLHSNV---NSYFGYSISSFIGQKEA--YCLVGAPRDEIDDESTNGNVNTGGVYR--ISFVNNDCSKVPMGSEGSGHVSPGYFNWLGGSVSTTVNGSNGVQLGCDPRFLSKTSYGVNKSEQQLLGIGQCSIYTG--STIRDISFLAC--SVTDEGA------CLSGFSSSVSADDSEKIKVALGMPGSFLTEGNIFLANFGPMSMIDKVLLKTSPSDLKNRGYNLGYDIKLARLWYGPKGRSPFINSFSNEVVVTSSP---HWKSNEYR---GVVLVLDTKLDLSQILYIPDMSGHL-GSNFGNSLAVGDFNGDKILDIIVGAPFYTDHWTSSKRLVDIGAIYIFY----GQVSDKFKYTVSNQNDVLKGVNVR----GKFGMSIANLGDIDGDDIDDFAVGCPNCGNDATGSVYIYLGGSKVPVQVIR-PRNLNHVLVTPQCSYMDDKEIMRSFQNFGWSLAGK-FDIDGNSVPDLIIGDYSSSQIVVLRSKNLI--WLENPV----WLLPTS-KSIEWTKYNEPDKPCFGDSCRYYMSLKAKVAGRKISTSEKIIFRVYIDLDTKLEHPFYK 572
BLAST of Alpha-int-3 vs. Planmine SMEST
Match: SMESG000018926.1 (SMESG000018926.1) HSP 1 Score: 52.7582 bits (125), Expect = 2.024e-6 Identity = 59/201 (29.35%), Postives = 95/201 (47.26%), Query Frame = 3
Query: 921 SGYGYSVLAMDLNNDGMDELVVGAPFTN----NNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPF-ENDGT-GAVYIYLGDS--------HQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQL 1481
S +G ++ + + +V+GAPF + N G+V+++ S+ ++++ P D L +K + +G L NIGDIN D QDLA+ +PF ND G V +Y + +QI+K SQK + I +G +I G D+D N +PD IV S S + +R ++Y + TD L
Sbjct: 296 SSFGVTLTTLSIFKGKRYAVVIGAPFHSVKSIQNVGKVYIFC------SSNKNRSAPSD-----FLHGKEK--DEFFGYFLANIGDINGDGNQDLAISSPFLRNDEIKGFVALYTINENCEMKQTPYQILK-SQKPKNAGI------FGIAITG-GSDMDFNGWPDIIVSSTRSNSIEMYASR---QLYTAKCIYSTDSNL 472
BLAST of Alpha-int-3 vs. Planmine SMEST
Match: SMESG000018926.1 (SMESG000018926.1) HSP 1 Score: 52.7582 bits (125), Expect = 2.328e-6 Identity = 59/201 (29.35%), Postives = 95/201 (47.26%), Query Frame = 3
Query: 921 SGYGYSVLAMDLNNDGMDELVVGAPFTN----NNNGQVFVYWNIEMSQSNIEHKTIPLDVEKRLLLTSMKKLSNGQYGISLENIGDINKDFIQDLAVGAPF-ENDGT-GAVYIYLGDS--------HQIIKLSQKIEGQMISPDLRGYGFSIFGKNEDLDSNTYPDFIVGSVLSGHVVGMRTRPIIRVYAENMVAETDMQL 1481
S +G ++ + + +V+GAPF + N G+V+++ S+ ++++ P D L +K + +G L NIGDIN D QDLA+ +PF ND G V +Y + +QI+K SQK + I +G +I G D+D N +PD IV S S + +R ++Y + TD L
Sbjct: 296 SSFGVTLTTLSIFKGKRYAVVIGAPFHSVKSIQNVGKVYIFC------SSNKNRSAPSD-----FLHGKEK--DEFFGYFLANIGDINGDGNQDLAISSPFLRNDEIKGFVALYTINENCEMKQTPYQILK-SQKPKNAGI------FGIAITG-GSDMDFNGWPDIIVSSTRSNSIEMYASR---QLYTAKCIYSTDSNL 472 The following BLAST results are available for this feature:
BLAST of Alpha-int-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Alpha-int-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Alpha-int-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Alpha-int-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Alpha-int-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Alpha-int-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Alpha-int-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032970 ID=SMED30032970|Name=Alpha-int-3|organism=Schmidtea mediterranea sexual|type=transcript|length=3827bpback to top protein sequence of SMED30032970-orf-1 >SMED30032970-orf-1 ID=SMED30032970-orf-1|Name=SMED30032970-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1091bp MEFINFIFLFLFHVPVLYFSYNIDLNSPYIKSNFINNKSFFGFSLNIFTSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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