TNF receptor associated factor 4
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032941 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18
Homology
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 127.102 bits (318), Expect = 5.754e-30 Identity = 134/518 (25.87%), Postives = 219/518 (42.28%), Query Frame = 2
Query: 137 SYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEY--LCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL-CEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEI-FVHTKLLM----DFVVNFNNEMEILKANNNGLSPVN---ELLRNEINE-------------LKLDG----DRRR-------------------------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEND--FQQQIAQC--ATNCQQAEIKQKELID-------KIGQMEN--KQKVDLTEMSNKID--------KLSGNVDR-KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
S +Y+ + +E+ C C +L N H CG RFC C+ L CP D E K ++ + D ++ L V C C + L + +DH++ C +Q QC SN C + + +D + +HL + F K L V+N N E L P N +L+ E++E K G D+RR +I DL + + +I+ L E I L + + + QV ++ + Q+ Q N QQ + + L++ KI +EN ++ L E +NK D +LS N +R KLLE NG+ +WK+ + K +A +G I+S+SF T + G+++C Y +GDG G+G+HLS++F +M+GEFD +L+WPFR VT L++Q + ++ D + +F +P + G +F++H L
Sbjct: 30 SIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIK------SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQC--SNEKCREPVLRKD-LKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTC-----YNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMET---FKPDPNSSSFKRPDGEMNIASGCPRFVAHSVL 530
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 127.102 bits (318), Expect = 5.754e-30 Identity = 134/518 (25.87%), Postives = 219/518 (42.28%), Query Frame = 2
Query: 137 SYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEY--LCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL-CEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEI-FVHTKLLM----DFVVNFNNEMEILKANNNGLSPVN---ELLRNEINE-------------LKLDG----DRRR-------------------------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEND--FQQQIAQC--ATNCQQAEIKQKELID-------KIGQMEN--KQKVDLTEMSNKID--------KLSGNVDR-KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
S +Y+ + +E+ C C +L N H CG RFC C+ L CP D E K ++ + D ++ L V C C + L + +DH++ C +Q QC SN C + + +D + +HL + F K L V+N N E L P N +L+ E++E K G D+RR +I DL + + +I+ L E I L + + + QV ++ + Q+ Q N QQ + + L++ KI +EN ++ L E +NK D +LS N +R KLLE NG+ +WK+ + K +A +G I+S+SF T + G+++C Y +GDG G+G+HLS++F +M+GEFD +L+WPFR VT L++Q + ++ D + +F +P + G +F++H L
Sbjct: 30 SIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIK------SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQC--SNEKCREPVLRKD-LKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTC-----YNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMET---FKPDPNSSSFKRPDGEMNIASGCPRFVAHSVL 530
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 127.102 bits (318), Expect = 5.754e-30 Identity = 134/518 (25.87%), Postives = 219/518 (42.28%), Query Frame = 2
Query: 137 SYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEY--LCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL-CEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEI-FVHTKLLM----DFVVNFNNEMEILKANNNGLSPVN---ELLRNEINE-------------LKLDG----DRRR-------------------------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEND--FQQQIAQC--ATNCQQAEIKQKELID-------KIGQMEN--KQKVDLTEMSNKID--------KLSGNVDR-KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
S +Y+ + +E+ C C +L N H CG RFC C+ L CP D E K ++ + D ++ L V C C + L + +DH++ C +Q QC SN C + + +D + +HL + F K L V+N N E L P N +L+ E++E K G D+RR +I DL + + +I+ L E I L + + + QV ++ + Q+ Q N QQ + + L++ KI +EN ++ L E +NK D +LS N +R KLLE NG+ +WK+ + K +A +G I+S+SF T + G+++C Y +GDG G+G+HLS++F +M+GEFD +L+WPFR VT L++Q + ++ D + +F +P + G +F++H L
Sbjct: 30 SIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIK------SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQC--SNEKCREPVLRKD-LKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTC-----YNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMET---FKPDPNSSSFKRPDGEMNIASGCPRFVAHSVL 530
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 123.635 bits (309), Expect = 3.182e-29 Identity = 114/489 (23.31%), Postives = 205/489 (41.92%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKC--NISQDKVTDHLQSEIFVHTKLLMDFV-VNFNNEM-----------EILKANNNGLSPVNELLRNEIN---------------ELKLDG-DRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + +LC LC K + + CG RFC C+ E+L E + CP D +L I D + V++ L ++C E C + LR ++ H+ C++ CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL E D + + L C NQ + ED+P N + L + ++ A+ ++ + K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ +S + +G+G G+G HLS++ ++ G FD +LEWPF VTF+L++Q + H + + D + F KP + GS FG+ +FISH+D+
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCP------NRCPMKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESV--------------KPHLAMMCALVSRQRQELQELRRELEELSVGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTE--TFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 124.02 bits (310), Expect = 6.551e-29 Identity = 98/371 (26.42%), Postives = 176/371 (47.44%), Query Frame = 2
Query: 377 LLVKCPEVLCEFQSELR-KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
++V CP C Q+ LR ++ H+ C S C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++ L
Sbjct: 200 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVL 543
BLAST of TNF receptor associated factor 4 vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 87.0409 bits (214), Expect = 9.012e-18 Identity = 35/103 (33.98%), Postives = 59/103 (57.28%), Query Frame = 2
Query: 1034 KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTR 1342
++L A + + +WK+DK + +AK+G + I+S F++H+ G+KM GDG G +S++ L+KGEFD LEWPF ++ +L++Q R
Sbjct: 249 RILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPR 351
BLAST of TNF receptor associated factor 4 vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 73.559 bits (179), Expect = 8.916e-14 Identity = 40/115 (34.78%), Postives = 64/115 (55.65%), Query Frame = 2
Query: 989 EMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADA-KNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALIN 1330
+ S +DK G + + + +A + ++ + +++ K + A KN + IYS+ F +H G+KM P GDG + SVF LMKGE+D ILEWPFR VTF++++
Sbjct: 131 QQSAYVDKYVGML--QYMSIAESAFEKYGSQHTFRIPKIGLTVVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILS 243
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 90.5077 bits (223), Expect = 1.163e-18 Identity = 44/136 (32.35%), Postives = 75/136 (55.15%), Query Frame = 2
Query: 1073 NGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGS-EFGFHQFISHRDLSANP 1477
G +WK+ ++ KMA+A+ + S F T + G+K+ S++ +G+G G+ H+SV+ ++ GE+D +L+WPF HS+TF L Q + + D + F +P ++ FGF +FISH L + P
Sbjct: 330 TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP 465
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 90.1225 bits (222), Expect = 1.470e-18 Identity = 44/136 (32.35%), Postives = 75/136 (55.15%), Query Frame = 2
Query: 1073 NGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGS-EFGFHQFISHRDLSANP 1477
G +WK+ ++ KMA+A+ + S F T + G+K+ S++ +G+G G+ H+SV+ ++ GE+D +L+WPF HS+TF L Q + + D + F +P ++ FGF +FISH L + P
Sbjct: 321 TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP 456
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0308606) HSP 1 Score: 60.077 bits (144), Expect = 3.526e-9 Identity = 26/95 (27.37%), Postives = 51/95 (53.68%), Query Frame = 2
Query: 1064 QRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLA 1348
Q I G +W++ ++ K+ ++K + I++S F G+ + L +Y +G G KG ++ +++ GE+D +L WP R + +Q T +A
Sbjct: 251 QNIRGHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVA 344
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074274) HSP 1 Score: 60.077 bits (144), Expect = 3.526e-9 Identity = 26/95 (27.37%), Postives = 51/95 (53.68%), Query Frame = 2
Query: 1064 QRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLA 1348
Q I G +W++ ++ K+ ++K + I++S F G+ + L +Y +G G KG ++ +++ GE+D +L WP R + +Q T +A
Sbjct: 251 QNIRGHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVA 344
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0334036) HSP 1 Score: 60.077 bits (144), Expect = 3.526e-9 Identity = 26/95 (27.37%), Postives = 51/95 (53.68%), Query Frame = 2
Query: 1064 QRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLA 1348
Q I G +W++ ++ K+ ++K + I++S F G+ + L +Y +G G KG ++ +++ GE+D +L WP R + +Q T +A
Sbjct: 251 QNIRGHLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVA 344
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2]) HSP 1 Score: 132.109 bits (331), Expect = 7.747e-32 Identity = 99/356 (27.81%), Postives = 165/356 (46.35%), Query Frame = 2
Query: 428 KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVN-ELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQ----RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
K DHI++C + C + +GCD + ++K+ DH Q+ + H LL+ F++ +K N L P + EL ++I+EL +++G L C A + AL + A+ + + ++ + + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM A + +G FVWK+ F+ K DA G ++S +F T K G+KMCL +Y +GDG G+G HLS+FF +M+G D +L+WPF VT L++Q R + DI +F +PVS
Sbjct: 201 KYVDHIKLCTKFRTPCRFHVVGCDM-TVEKEKIHDHEQACSYEHLNLLLHFIMG-------IKVNLESLQPQSLELASHKIHELHQSLRELELKMGQL---CGAGASV-----QGACALPPPPPPAPTLGTSFTPLPTAVGAALELQLHSEKTKVVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDA---FRPDISSSSFQRPVS 535
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 121.324 bits (303), Expect = 1.264e-28 Identity = 111/480 (23.12%), Postives = 211/480 (43.96%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNI--SQDKVTDHLQSEIFVHTKLLMDFVVN-FNNEMEILKANNNGLSPVNELL-RNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQL------IIEGNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + C LC K + + CG RFC C+ E+L E + CP D +L I D + +I L ++C E C + ++++++ H C + CP ++C++ ++ + +HLQ + K+ +F + F E N+ G+ P + N+ + RR+ +C + + + ++ V D + Q + NQ +A + N ++ C E K K+ +E K LT M + + + + R++ E++ + + G +WKL ++ K+ +AK N +S F TH+ G+K+ +S + +G+G G+G+HLS++ ++ GE+D +LEWPF + VTF++++Q ++ H + + D + F KP S S FG+ +FISH ++
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCP------NRCSVKLTRRDLPEHLQHDC-PKRKVKCEFCGSEFTGEA---YENHQGICPQESVYCENKCGARMM----RRLLSQHTMTECPKRTQPCKYCGKEF---------VYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCSLVGRQRQEILELRREMEELSVSHD----GVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFN--PDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 121.324 bits (303), Expect = 1.264e-28 Identity = 111/480 (23.12%), Postives = 211/480 (43.96%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNI--SQDKVTDHLQSEIFVHTKLLMDFVVN-FNNEMEILKANNNGLSPVNELL-RNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQL------IIEGNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + C LC K + + CG RFC C+ E+L E + CP D +L I D + +I L ++C E C + ++++++ H C + CP ++C++ ++ + +HLQ + K+ +F + F E N+ G+ P + N+ + RR+ +C + + + ++ V D + Q + NQ +A + N ++ C E K K+ +E K LT M + + + + R++ E++ + + G +WKL ++ K+ +AK N +S F TH+ G+K+ +S + +G+G G+G+HLS++ ++ GE+D +LEWPF + VTF++++Q ++ H + + D + F KP S S FG+ +FISH ++
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCP------NRCSVKLTRRDLPEHLQHDC-PKRKVKCEFCGSEFTGEA---YENHQGICPQESVYCENKCGARMM----RRLLSQHTMTECPKRTQPCKYCGKEF---------VYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCSLVGRQRQEILELRREMEELSVSHD----GVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFN--PDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1) HSP 1 Score: 111.694 bits (278), Expect = 7.399e-27 Identity = 68/206 (33.01%), Postives = 106/206 (51.46%), Query Frame = 2
Query: 875 FQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQ----RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
Q Q+ + + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM A + +G FVWK+ F+ K DA G ++S +F T K G+KMCL +Y +GDG G+G HLS+FF +M+G D +L+WPF VT L++Q R + DI +F +PVS
Sbjct: 35 LQPQMVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDA---FRPDISSSSFQRPVS 235
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Match: AL844899.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28760787:-1 gene:ENSDARG00000111038.1 transcript:ENSDART00000183806.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844899.1) HSP 1 Score: 111.694 bits (278), Expect = 7.399e-27 Identity = 68/206 (33.01%), Postives = 106/206 (51.46%), Query Frame = 2
Query: 875 FQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQ----RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
Q Q+ + + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM A + +G FVWK+ F+ K DA G ++S +F T K G+KMCL +Y +GDG G+G HLS+FF +M+G D +L+WPF VT L++Q R + DI +F +PVS
Sbjct: 35 LQPQMVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDA---FRPDISSSSFQRPVS 235
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 129.413 bits (324), Expect = 7.701e-31 Identity = 119/506 (23.52%), Postives = 221/506 (43.68%), Query Frame = 2
Query: 140 YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL---------CENR---------------------YCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHI-RMCNYQSSQ--------------------CPYSNIGCDK-CNI--------SQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISH 1456
Y + +E++ C C+ +L N CG RFC C++ L CE+ +C +T CK ELI++ N+++ + + +L CP C+ + + + DHI + C Y+ + CP I C C++ + ++ H S H L+ ++ ++ +L+ ++ + ++L N++ +++ +R + I LQR QA++++ L+++I RN+ R D DG++ E Q + +E +A+ A + ++ + I++ QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ V+ L++Q H GD ++ D + +F KP + G F++
Sbjct: 34 YKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCK-ELITLG-NLLIHLKSDCQFEEL--SCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEI---RNL-RQTGDEADGMKSNYESLQNRLSQLE-----VMAKNAASWNPGVLETQ--INRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQ 508
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 121.324 bits (303), Expect = 1.458e-28 Identity = 107/489 (21.88%), Postives = 208/489 (42.54%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQ---------------------SSQCPYSNIGCDKC--NISQDKVTDH----LQSEIFVHTKL---LMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M YDY+ + ++ + LC LC K + + CG RFC C+ E+L E + CP D +L I DR + ++ L ++C E C + +L++++ H+ +C + CP + C+ C + + + DH Q ++ K +M V++ ++ +E K E + + I + R C NQ + ED+ ++ D + + + ++ + T + E + + + + ++Q+ ++ E+ ++++LS + + G +WK+ ++ K+ +AK N +S F THK G+K+ +S + +G+G G+G++LSV+ ++ GE+D +LEWPF + VTF+L++Q ++ H + + D + F KP S FG+ +FISH D+
Sbjct: 1 MPGYDYKFLEKLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPR-------YPTPCPNQCGIASIAREDL------SNHLKDSC--------SSALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSMMSSLVSRQRQEILELRKQVEELSVSSE---------------GVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFN--PDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 120.553 bits (301), Expect = 7.432e-28 Identity = 121/516 (23.45%), Postives = 216/516 (41.86%), Query Frame = 2
Query: 140 YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL---------CENR---------------------YCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHI-RMCNYQSSQCPY-------------SNIGCDKCNISQD---KVTDHLQSEIFVH---------TKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNE-------DIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVD-------LTEMSNKIDKLSGNVDRKLLEMAAN----QNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
Y + +E++ C C+ +L N CG RFC C++ L CE+ +C +T CK ELI++ N+++ + + +L CP C+ + + + DHI + C Y+ + C + ++ C IS V L+SE+ H T + F + +KA+ S V +N +K + ++ LQ + + + + I++L+ +I + RN R+ LQ +IEG ++ ++ + + + Q + + L +++ Q+E K L N+ D++ D +L +M + NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ V+ L++Q H GD ++ D + +F KP + G F++ L
Sbjct: 34 YKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCK-ELITLG-NLLIHLKSDCQFEEL--SCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEAS-SAV-----QHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEI-RNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVL 536
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Match: hspb6 (heat shock protein family B (small) member 6 [Source:Xenbase;Acc:XB-GENE-876273]) HSP 1 Score: 113.62 bits (283), Expect = 1.853e-26 Identity = 52/126 (41.27%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 1040 LEM--AANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPV 1411
LEM A + +G F+WK+ T+K DA G +YS +F T K G+K+CL +Y +GDG GKG H+S+FF +MKGE+D +L WPF+H VTF L++ R + F + D+ +F +P+
Sbjct: 216 LEMRSACLEQTSYDGVFLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDHNNRDSVFDA---FRPDVTSASFQRPI 338
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 107.071 bits (266), Expect = 9.290e-24 Identity = 95/376 (25.27%), Postives = 175/376 (46.54%), Query Frame = 2
Query: 383 VKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEI--------ELLNEDIPALRNVDRNVSDRLDGLQLII-EGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDR-KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPE 1480
V CP C +++ H+ C QC +SN GC+ + + KV +H + F+ +L +V+N N ++E GL +L ++I +L D + C + + L+ +D+++ +QL+ E +++ +R + + + + +T + D+I ++ + K +SN +++ N +R +L+E + NG+ +WK+ + K +A G I+S+ F T G+++C Y +GDG GKG+ LS++F +MKGEFD IL WPF+ VT L++Q + H + D+ + D + +F +P S+ G +F SH L NP+
Sbjct: 125 VPCPNA-CPVTCPRAELDKHLCECPEAELQCTFSNYGCN-VMVKRGKVKEH--EDTFLRDHML--YVLNRNMKLE---EQVLGLQQNLDLKEHQIQQL-----------SDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLST--------LEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTS-----YNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHIT-DV-FRADPNSSSFKRPDSEMNIASGCPRFASHAQLE-NPK 464
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Match: Traf4 (TNF receptor associated factor 4 [Source:MGI Symbol;Acc:MGI:1202880]) HSP 1 Score: 125.176 bits (313), Expect = 5.423e-30 Identity = 115/482 (23.86%), Postives = 209/482 (43.36%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKC--NISQDKVTDHLQSEIFVHTKLLMDFV-VNFNNEMEILKANNNGLSPVNELL-RNEINEL---KLDGDRRRVEIGDLQRKCAN----------QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC------QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + +LC LC K + + CG RFC C+ E+L E + CP D +L I D + V++ L ++C E C + LR ++ H+ C++ CP ++C +S+ + HLQ + +L +F +F+ E ++ G+ P + N+ +L E + CA Q+ + + +P R D + + A V F++ + C C + E K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ +S + +G+G G+G HLS++ ++ G FD +LEWPF VTF+L++Q + H + + D + F KP + GS FG+ +FISH+D+
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCP------NRCPAKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEA---YESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAF--VLCPFKE--SGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTE--TFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 123.635 bits (309), Expect = 5.020e-29 Identity = 98/371 (26.42%), Postives = 176/371 (47.44%), Query Frame = 2
Query: 377 LLVKCPEVLCEFQSELR-KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
++V CP C Q+ LR ++ H+ C S C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++ L
Sbjct: 199 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVL 542
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 120.939 bits (302), Expect = 3.513e-28 Identity = 117/502 (23.31%), Postives = 214/502 (42.63%), Query Frame = 2
Query: 140 YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR-YCPGDTED-----------CKLELISIT---ENIMVDRPMNVKISKLLV-----------KCPEVLCEFQSELRKMEDHI-RMCNYQSSQ--------------------CPYSNIGCD-KCNI--------SQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISH 1456
Y + + +ED+ C C+ +L N CG RFC C++ L + C E CK E++++ N + + LLV C C+ + + + DH+ + C Y+ + CP + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++
Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF----RQNWEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQ 514
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 120.939 bits (302), Expect = 3.513e-28 Identity = 117/502 (23.31%), Postives = 214/502 (42.63%), Query Frame = 2
Query: 140 YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR-YCPGDTED-----------CKLELISIT---ENIMVDRPMNVKISKLLV-----------KCPEVLCEFQSELRKMEDHI-RMCNYQSSQ--------------------CPYSNIGCD-KCNI--------SQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISH 1456
Y + + +ED+ C C+ +L N CG RFC C++ L + C E CK E++++ N + + LLV C C+ + + + DH+ + C Y+ + CP + C KC++ + ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++
Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPF----RQNWEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQ 514
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 108.997 bits (271), Expect = 1.764e-24 Identity = 56/149 (37.58%), Postives = 84/149 (56.38%), Query Frame = 2
Query: 992 MSNKIDKLSGNVDRKLLEMAANQNQRIN--------GEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
+SNK+ +L ++ K L MA + Q+++ G F+WK+ FT K +A G I+S +F T + G+KMCL VY +GDG G+G HLS+FF +MKG D +L+WPF VT L++ R + D+ +F +PVS
Sbjct: 317 LSNKVQQLERSIGLKDLAMA-DLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDA---FRPDVTSSSFQRPVS 461
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2) HSP 1 Score: 127.102 bits (318), Expect = 2.763e-29 Identity = 134/518 (25.87%), Postives = 219/518 (42.28%), Query Frame = 2
Query: 137 SYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEY--LCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL-CEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEI-FVHTKLLM----DFVVNFNNEMEILKANNNGLSPVN---ELLRNEINE-------------LKLDG----DRRR-------------------------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEND--FQQQIAQC--ATNCQQAEIKQKELID-------KIGQMEN--KQKVDLTEMSNKID--------KLSGNVDR-KLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
S +Y+ + +E+ C C +L N H CG RFC C+ L CP D E K ++ + D ++ L V C C + L + +DH++ C +Q QC SN C + + +D + +HL + F K L V+N N E L P N +L+ E++E K G D+RR +I DL + + +I+ L E I L + + + QV ++ + Q+ Q N QQ + + L++ KI +EN ++ L E +NK D +LS N +R KLLE NG+ +WK+ + K +A +G I+S+SF T + G+++C Y +GDG G+G+HLS++F +M+GEFD +L+WPFR VT L++Q + ++ D + +F +P + G +F++H L
Sbjct: 30 SIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIK------SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQC--SNEKCREPVLRKD-LKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTC-----YNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMET---FKPDPNSSSFKRPDGEMNIASGCPRFVAHSVL 530
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Match: sp|Q61382|TRAF4_MOUSE (TNF receptor-associated factor 4 OS=Mus musculus OX=10090 GN=Traf4 PE=1 SV=2) HSP 1 Score: 125.176 bits (313), Expect = 3.793e-29 Identity = 115/482 (23.86%), Postives = 209/482 (43.36%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKC--NISQDKVTDHLQSEIFVHTKLLMDFV-VNFNNEMEILKANNNGLSPVNELL-RNEINEL---KLDGDRRRVEIGDLQRKCAN----------QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNC------QQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + +LC LC K + + CG RFC C+ E+L E + CP D +L I D + V++ L ++C E C + LR ++ H+ C++ CP ++C +S+ + HLQ + +L +F +F+ E ++ G+ P + N+ +L E + CA Q+ + + +P R D + + A V F++ + C C + E K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ +S + +G+G G+G HLS++ ++ G FD +LEWPF VTF+L++Q + H + + D + F KP + GS FG+ +FISH+D+
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCP------NRCPAKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEA---YESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAF--VLCPFKE--SGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTE--TFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDI 445
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Match: sp|Q9BUZ4|TRAF4_HUMAN (TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1) HSP 1 Score: 123.635 bits (309), Expect = 1.528e-28 Identity = 114/489 (23.31%), Postives = 205/489 (41.92%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKC--NISQDKVTDHLQSEIFVHTKLLMDFV-VNFNNEM-----------EILKANNNGLSPVNELLRNEIN---------------ELKLDG-DRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + +LC LC K + + CG RFC C+ E+L E + CP D +L I D + V++ L ++C E C + LR ++ H+ C++ CP ++C +S+ + HLQ + +L +F +F+ E + N G + LL E D + + L C NQ + ED+P N + L + ++ A+ ++ + K + + + ++Q+ +L E+ ++++LS D G +WK+ + ++ +AK N +S +F THK G+K+ +S + +G+G G+G HLS++ ++ G FD +LEWPF VTF+L++Q + H + + D + F KP + GS FG+ +FISH+D+
Sbjct: 1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCP------NRCPMKLSRRDLPAHLQHDC-PKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESV--------------KPHLAMMCALVSRQRQELQELRRELEELSVGSD---------------GVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTE--TFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDI 445
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2) HSP 1 Score: 124.02 bits (310), Expect = 3.146e-28 Identity = 98/371 (26.42%), Postives = 176/371 (47.44%), Query Frame = 2
Query: 377 LLVKCPEVLCEFQSELR-KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
++V CP C Q+ LR ++ H+ C S C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++ L
Sbjct: 200 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQVARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVL 543
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 123.635 bits (309), Expect = 3.511e-28 Identity = 98/371 (26.42%), Postives = 176/371 (47.44%), Query Frame = 2
Query: 377 LLVKCPEVLCEFQSELR-KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
++V CP C Q+ LR ++ H+ C S C + GC +Q ++ H S H LL ++ + ++ +L+ + + + L N+I +++ +R++ +I LQR +QAE+++ L+++I R + D ++ +E Q + +E+ + Q A N E + + + QM + + L +M + ++LE A+ NG +WK+ + + +A G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q + H GD ++ D + +F KP + G F++ L
Sbjct: 199 VVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQ-QIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN----WEEADSMKSSVESLQNRVTELES-VDKSAGQAARNTGLLESQ----LSRHDQMLSVHDIRLADMDLRF---------QVLETAS-----YNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHL-GDA-FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVL 542
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Match: A0A0F7GWW3 (TNF receptor associated factor 4 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 293.123 bits (749), Expect = 1.793e-91 Identity = 145/166 (87.35%), Postives = 152/166 (91.57%), Query Frame = 2
Query: 326 ITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGL 823
+ ENI VD PMN+KI+KL VKC E C++ ELRKMEDH R C Y+S CPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEME+LKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGL
Sbjct: 12 LNENICVDYPMNMKIAKLQVKCKEKSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEMLKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGL 177
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 177.563 bits (449), Expect = 9.493e-45 Identity = 121/455 (26.59%), Postives = 238/455 (52.31%), Query Frame = 2
Query: 98 MATKLENIWESMKSYDYETIGE-IEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR-YCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFV------VNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ--RING-------EFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYE-LDIDGDAFCKP 1408
+ +KL+N+ E + Y+ + + E + +++LC+LC KL+ +A + CGC +C+ C+ YL +N YCPGD +CK + +++ ++ + ++ +IS+++VKCP + C + SEL ++++H+ C +S +CP IGC++ + +D++ HL ++ HT+L+M F +N NNE +S + E+LR + K D + ++ L + N+ I +L++DI ++N + ++ + ++ +++D QI + Q+ E + +L + +G + K +V ++ +I + N+D E N R+N +F+W++++++ K + +YS+SF +H +K CL++Y GD G ++ +MKGE D LEWP R +VT ++I Q + H + Y+ + AF +P
Sbjct: 2 IPSKLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNE-----TTKEDISHLKEVLRVQ----KALNDEKTAQMEFLIEELRNKDNMILVLSQDIQEVKN----------EMITLLTSKESELKKLKSDI--QIFR-----QEIEFMKNDL-EVVGSTDIKNQV--KDLKKEIFGIKMNIDSNNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSKKRRTVTD-----VYSDSFQSH--NYKFCLNLYIYGDNLG------LWCVIMKGEKDDFLEWPMRRTVTLSIIEQDSLKTHKTTVFQYDTYQRNKKAFDRP 414
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Match: A0A5A9NXF1 (TNF receptor-associated factor OS=Triplophysa tibetana OX=1572043 GN=E1301_Tti007446 PE=3 SV=1) HSP 1 Score: 149.443 bits (376), Expect = 1.541e-34 Identity = 128/467 (27.41%), Postives = 204/467 (43.68%), Query Frame = 2
Query: 167 EDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR--YCPGDTEDCKLEL---ISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQ---------------------SSQCPYSNIGCDKCNI---------SQDKVTDHLQSEIFVHTKLLMDFVVNFNNEM--------EILKANNNGLSPVNELLRNEINELKLDGDRRRV-----EIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDF--QQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSK 1417
+++ LC C +L A CG R+C CV+ L N+ C ED +E + + D +N +I L V C C ++S L+ EDH C Y CP + C C+ + DKV +H H +LL++ + + + EIL G + + L+ +E +EL+ DG V + D Q + A ++++ L + + + N+ + L +E Q+ + A+E D QQI Q Q E K +E + + ++ + +T + I L QN +G F+W+L T + +A G YS +F T + GFK+C+ +Y +GDG GKG H+S+FF +MKGE+DGIL+WPFRH VTF LI+Q R + D+ +F +PVS+
Sbjct: 35 KEKFLCSNCNNVLNKARQTVCGHRYCLACVNWLLRNNKDLVCTKCKEDQSIESDTSVLTLDQFFNDAAINKEILDLKVHCANQGCPWRSTLKNFEDHQSQCEYALIPCNIGCGIMVQRKALATHLERGCPNNKTTCASCSGVLTPRELQGNADKVKEHESCSHVGHLQLLLEVIRGLQSNLSSQERGIPEILDFLQPGTTG-SSLVSHEESELETDGGESGVNDKASSLHDDQAELA-VGQQLDTLQQRVQVMENI-------ISALNREVEKTQIGVVALERDNLNNQQIIQ------QLETKVEEQQEWL----TRKDIHITSLQQCISGL--------------QNVSYDGTFLWRLCDVTQSLREAATGHKISQYSPAFYTARYGFKVCMRLYLNGDGVGKGTHISLFFVIMKGEYDGILQWPFRHKVTFFLIDQNQREHVIDA---FRPDLCSASFHQPVSE 465
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 140.584 bits (353), Expect = 2.719e-34 Identity = 76/190 (40.00%), Postives = 113/190 (59.47%), Query Frame = 2
Query: 113 ENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCE-NRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELK 679
E I + +Y++E G + D + C LCK LLVNA + CGCRFC C+ EY+ N YCPG T +CK E ++I NI D +N KI+K+ VKCPE C+ EL +E+H+R+C +S CP+ +GC++ + +T+HLQ+ F H+KL++D + N N+ GL+ LR +IN +K
Sbjct: 4 EKINRLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFF-------GLTTKEVELREDINLIK 186
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 147.132 bits (370), Expect = 3.610e-34 Identity = 120/444 (27.03%), Postives = 207/444 (46.62%), Query Frame = 2
Query: 164 IEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCEN--RYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQ--DKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILK-ANNNGLSPVNELLRNEINELKLDG--DRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQM--ENKQ-KVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
I D + C++C+ +L++A CGCR+C C+ YL EN + C + EDC+ S+ + + DR N +IS L VKC C F+ L+ ++ H+ C Y+ N C C + + ++HL +E LL + + + + K N + L + L + + G +V + ++ C N+ E L D L I +Q+ + ++ + T ++ E + K + +++ + EN+ K L M + K SG++ R AN+ NG+++WK+ F+ +A G N I SE+F T G+KMC+ +YP GDG GKG HLS+FF +MKG++D IL WPF++ V + + ++ + S ++ D + +P + G +FIS +L
Sbjct: 25 INDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYL-ENGEKECVAEYEDCR----SVITSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYR-------NEMCSLCGMEYIIKEESNHLANEC-----LLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQL-----------------IPKDQMTEHLNTSSYEHTLT-IVTELRKLEKQNKHMEERMNILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSD--TFKPDPKSICYQRPEEEYNIASGSPKFISFSEL 431
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 133.265 bits (334), Expect = 3.087e-32 Identity = 104/362 (28.73%), Postives = 168/362 (46.41%), Query Frame = 2
Query: 428 KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVN-ELLRNEINELKLDGDRRRVEIGDL------QRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQ----RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
K DHI++C + C + +GCD ++ ++K+ DH ++ + H LL+ F++ +K N L P + EL ++I EL +++G L Q CA L L V L+ LQL E + ++A+ + CQ+ E+K +E+ ME N+Q K+++ ++NK+ +L V D ++EM + +G FVWK+ F+ K DA G ++S +F T K G+KMCL +Y +GDG G+G HLS+FF +M+G D +L+WPF VT L++Q R + DI +F +PVS
Sbjct: 201 KYVDHIKLCTKFRTPCRFHVVGCDM-SVEKEKIHDHERACSYEHLNLLLHFIMG-------IKVNLESLQPQSLELASHKIQELHQSLRELELKMGQLSAGAPVQGACAPPPPPPPTLATSFTPLPTT---VGAALE-LQLHSE-------------KTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEI--LNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDA---FRPDISSSSFQRPVS 532
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 117.857 bits (294), Expect = 1.166e-27 Identity = 110/480 (22.92%), Postives = 210/480 (43.75%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNI--SQDKVTDHLQSEIFVHTKLLMDFVVN-FNNEMEILKANNNGLSPVNELL-RNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQL------IIEGNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M YDY+ + + + C LC K + + CG RFC C+ E+L E + CP D +L I D + +I L ++C E C + ++++++ H C + CP ++C + ++ + +HLQ + K+ +F + F E N+ G+ P + N+ + RR+ +C + + + ++ V D + Q + NQ +A + ++ C + K K+ +E K LT M + + + + R++ E++ + + G +WKL+ ++ K+ +AK N +S F TH+ G+K+ +S + +G+G G+G+HLS++ ++ GE+D +LEWPF + VTF++++Q ++ H + + D + F KP S S FG+ +FISH ++
Sbjct: 1 MPGYDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCP------NRCAVKLTRRDLPEHLQHDC-PKRKVKCEFCGSEFTGEA---FENHQGICPQESVYCENKCGARMM----RRLLAQHTMAECPKRTQPCKYCGKEF---------VYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSHLTMMCSLVGRQRQEIIELRREMEELSVSHD----GVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFN--PDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Match: traf5 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:103031120]) HSP 1 Score: 117.472 bits (293), Expect = 3.638e-27 Identity = 93/371 (25.07%), Postives = 171/371 (46.09%), Query Frame = 2
Query: 383 VKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRN---EINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSA 1471
V+CP C + K++DH C Q + C Y GC N + +V H Q+E H LL L++N+ + V++L ++ + ELK R + + +L+R+ + + + + R + +V L L+ ++E + V++RA + ++Q+A + L + +G + + + + +L + R ++ +G+ +WK+ + K +A +N S F T +G+K+ VY G+G +G HLS++ LM+G+FD +L WPFR +VT A+++Q H S L + D+ + F +P S+ + GF +FI+H DL A
Sbjct: 195 VQCPNK-CIHLVKRHKLKDHADECPEQETDCIYKKYGCTVRN-KRGQVKVHEQTEFNHHVLLL-------------LESNSKLIKQVDQLQQDFAAQQGELK----ERNLLVSNLKREVSKCDTTVSAMQRSVEEQRELVSSVKRELKDLRDVLEADLTKEELVSLRASLDSLREQVAM-----------TQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQR----FQQLESTSYDGKLIWKVHDYHRK-KEAGTALN----SPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVS--LSFTPDLASNNFRRPTSETNAALGFPRFITHADLEA 524
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 112.464 bits (280), Expect = 1.363e-25 Identity = 85/320 (26.56%), Postives = 147/320 (45.94%), Query Frame = 2
Query: 473 CPYSNIGCD-KCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDL---QRKCANQAEEIEL-LNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSK 1417
C +S IGC K N DKV +H S H LL++ V N + P ++ +L L+G + GD + + ++ EL + + + AL+ + + + + L +E Q+ + +E D + LI + + +Q+ L +I L ++ +A Q+ +G F+W++ + K+ +A G + YS +F T + GFK+C+ +Y GDG GKG H+S+FF +MKG++D +L WPF+ VTF LI+Q R + D+ +F +PVS+
Sbjct: 196 CVFSEIGCTFKGN--PDKVREHEVSSTSAHLHLLVEVVRNVQMSVP---------PPPERTVQYPALDLTLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNM---------------NLIQHLEAVVAEQQQRLIRKDLQISSLQQSI-------SAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDA---FRPDLRSASFQRPVSE 479 HSP 2 Score: 51.6026 bits (122), Expect = 2.276e-6 Identity = 38/115 (33.04%), Postives = 50/115 (43.48%), Query Frame = 2
Query: 176 MLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR--YC------PGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGC 496
LC C +L AH CG R+C CV L N+ C PG D + L ++ D +N +I +L V C C ++S L+ EDH C Y C NIGC
Sbjct: 27 FLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSMML--TLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGC 136
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 112.079 bits (279), Expect = 2.073e-25 Identity = 85/324 (26.23%), Postives = 151/324 (46.60%), Query Frame = 2
Query: 473 CPYSNIGCD-KCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNE----INELKLDGDRRRVEIGDL---QRKCANQAEEIEL-LNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSK 1417
C +S IGC K N DKV +H S H LL++ V N + ++ L+N+ + ++ L+G + GD + + ++ EL + + + AL+ + + + + L +E Q+ + +E D + LI + + +Q+ L +I L ++ +A Q+ +G F+W++ + K+ +A G + YS +F T + GFK+C+ +Y GDG GKG H+S+FF +MKG++D +L WPF+ VTF LI+Q R + D+ +F +PVS+
Sbjct: 206 CVFSEIGCTFKGN--PDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLHLQNQDMTPLPDITLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQLTVVVLERDNHNNM---------------NLIQHLEAVVAEQQQRLIRKDLQISSLQQSI-------SAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDA---FRPDLRSASFQRPVSE 502 HSP 2 Score: 51.9878 bits (123), Expect = 2.143e-6 Identity = 38/115 (33.04%), Postives = 50/115 (43.48%), Query Frame = 2
Query: 176 MLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENR--YC------PGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGC 496
LC C +L AH CG R+C CV L N+ C PG D + L ++ D +N +I +L V C C ++S L+ EDH C Y C NIGC
Sbjct: 27 FLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESDSSMML--TLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGC 136
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 124.02 bits (310), Expect = 1.213e-30 Identity = 101/408 (24.75%), Postives = 176/408 (43.14%), Query Frame = 2
Query: 284 CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEI----LKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLD--GLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKL--LEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
CP E CK ++T +++ +R + ++ + CP E ++ H+ C + C + +GC + + V +H +S + H L V++ N+E+E+ L+ + + ++E+L + +L+ D G + + E + NE + +L R D L+ + + +RA+E C C E Q++ + D L +R+L LE A +G+ VWK+ + + +A +G +YS+ F T G+KMC Y +GDG G+G HLS+FF +M+GE+D +LEWPFR VT +L++Q H S + D +F +P G F+SH L + L
Sbjct: 29 CPHRAEFCKYCSAAVTCSLL-ERHHKEECAQYPLPCPNNCEEHGIPRAELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTL----VISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNP-GPCEERCHMHE----------------QRLTMH------DGLLDTAERRLQVLETAG-----YSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSD--TFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYL 401
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.553 bits (301), Expect = 3.974e-29 Identity = 97/391 (24.81%), Postives = 171/391 (43.73%), Query Frame = 2
Query: 362 VKISKLLVKCPEVLCEFQSELRK-MEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGD-----------LQRKCANQAEEIELLNEDIPAL-RNVDRN-VSDRLDGLQLIIE--GNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSG-NVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
+ + + CP CE QS R+ + H+ +C Y+ ++C +S GC K + + +H H L+ N ++ +L++ + +LL + EL ++ + +G +QR A Q E + L E + R D + + LDG + G +VA A+E + ++ +++ T++ +L+ ++ ++LE A+ NG+ VWK+ + + DA +G +YS+ F T G++MC Y +GDG G+G HLS+FF +M+GE+D +L WPFR VT L++Q S ++ D +F +P S G F+SH L + L
Sbjct: 96 TRCPRYPIPCPNK-CEEQSIAREELVSHLGICPYKQAECFFSQFGC-KYKGTLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVREL----EKELISVGQTASKNESVLCVVQRMLAVQTERLLRLQESMQGTTRRADHDALRGDLDGTAATLHELGTRVA--AIEES-------------GGSVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETAS-----YNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSD--TFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYL 458
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 81.6481 bits (200), Expect = 2.040e-16 Identity = 109/510 (21.37%), Postives = 206/510 (40.39%), Query Frame = 2
Query: 134 KSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITEN-IMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCN--ISQDKVTDHLQSEIF------VHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEIN-ELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRL--DGLQL----IIEGNQVAMRAVEN---------------DFQQQIA--------QCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSG------NVDRKLLEMAANQNQRI-NGEFVWKLDKFTDKMAD------AKNGIN----AIIYSESFLTHKNGFKMCLSV-------YPDGDG------GGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTR-LAHFSGDLDYELDIDGDAFCKP-VSKCGSEFGFHQFI 1450
+ Y+ + +E + C +C L PCG RFC C+ + P C ++ + E + D +I L V+CP C + ELR +++H +C Y+ + C +C + + + H + E +H M + + N+E N EL+R ++ L++D + +V C E +++ + A + V RL +GL++ + +G Q + A + D Q A + A +C Q + +E+ + + Q + E+S K D G + R L A R+ G F W++++F+ + A +G++ A+++S F T G+++CL + P G G+ HL++F HL++G++D L WPF+ + ++++Q R H + +D + + AF +P V + FG+ F+
Sbjct: 49 QGYEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGP----KCPVDNAVLHEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEH-------QLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSKNHEQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGC-----EAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQL--SAFQRPSVHRNPKGFGYMNFM 540
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.5286 bits (127), Expect = 9.125e-8 Identity = 30/133 (22.56%), Postives = 61/133 (45.86%), Query Frame = 2
Query: 920 EIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLL----EMAANQNQRINGEFVWKLDKFTDKMADAKNGIN--AIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPF 1300
+++ E + G ++ + L +++ +R +L +A +N NG F+WK+ +++ +A NG I S +F T + G+++ L + G+ H+S + L G +D L WP+
Sbjct: 269 DVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPY 395
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Match: rnf41l (ring finger protein 41, like [Source:ZFIN;Acc:ZDB-GENE-030131-9441]) HSP 1 Score: 48.9062 bits (115), Expect = 2.247e-7 Identity = 33/120 (27.50%), Postives = 55/120 (45.83%), Query Frame = 2
Query: 137 SYDYET-IGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL--CEFQSELRKMEDHIRMCNYQSSQCPYSN 487
YD E +G ++D +LC +C+ +L + APC FC C+ +L N CP D + + +E + R M ++ L + C CE L + H + C Y + CP++
Sbjct: 2 GYDAERFVGRVKDGLLCCVCRDVLEDPLQAPCEHAFCSACIHGWLVHNHTCPEDRQP-----LDASELRPLFRYMRNDLNALRLHCTHRARGCEGVCALETIAIHEQQCPYTPTPCPHTG 116
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 139.813 bits (351), Expect = 5.317e-35 Identity = 131/515 (25.44%), Postives = 215/515 (41.75%), Query Frame = 2
Query: 155 IGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCP--EVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGC-------------DKC------------NISQDKVTDHLQS-------------------EIFVH-------TKLLMDFV---VNFNNEMEILKAN--NNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNV------DRKLLEMAANQNQ--------------RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDL 1465
+ ++ + C +C L + PCG RFC C+ L CP D E+ K++ + +++ R +I L CP ++ CE+ +L+ +E+H C Y+ QC N GC ++C I + DHLQ+ E+ H +L F +F E L+ + + VN LL NE K + ++ ++++ A Q E++ E + R +L+ +IE + R + +++I Q+ E +E ++G +EN+ S + G + DR ++A + Q +G ++WK+D++T + + +G IYS F + G+K C VYP+GDG GKG+HLS+FF LM+GEFD +L WPFR VTF L++Q H GD + D +F +P S G FISH +L
Sbjct: 12 VEPLDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGPSKCPVDGEELKID--GVFKDVCCRR----EILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQC--HNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHLQTCEKHPVVCPHCGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMA-AKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLN----VIERSVAEQRRELAELKERI-----QLQEVEAAIREQDRRLGMIENEASRGAAPSSGP-GSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDR--VHDIGDT-FRPDPTSSSFKRPTSNMNIASGCPLFISHTNL 504
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 130.183 bits (326), Expect = 8.168e-32 Identity = 86/330 (26.06%), Postives = 152/330 (46.06%), Query Frame = 2
Query: 365 KISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLL-------MDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQ 1333
K ++CP + E +K+ H R C + C +S +GC + + + +H + H LL ++ N++E N E + E ++K + + +G +++ ANQ +I + R D L+ +V MR + + C + +K+ E+ D NK L+++ + I + ++ L + Q +G F+WK+DKFT++ A+AK+G IYS F TH+ G+K+C ++P+GDG + N+LS+F LM+GE+D IL WPF+ ++T LI+Q
Sbjct: 155 KCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCRFSPLGCTY-KVKKIALREHQNKHVIKHMILLGRTTGEPQPNLLELENQLERFDGENTSFKTELERHKYEFAQMKERFNDQNARLGIVEKTVANQKGDIA--------------EIWMRFDQENLV---GEVRMRDKLKK-FKVKTKANKECLLSLMKRLEVQDDSQTNPNKLNRRLSQLESSITIHKTKLFQEDLRIQIQQAISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQ 465
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 121.709 bits (304), Expect = 2.645e-29 Identity = 105/408 (25.74%), Postives = 182/408 (44.61%), Query Frame = 2
Query: 140 YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRY--CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGD-LQRKCANQAEEIELLNEDIP-ALRNVDRNVSDRLDGLQLIIEGNQVAMRAVEN----DFQQQIAQCATNCQQAEIK-QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR 1336
YD E + + +E C +C L CG RFC C+ E CP D E + + +++ +D+ I LVKCP C++++ELR +E H R C+Y+ C SN C + + V +HL E +L++ + + KA+ N + +L R+++ + L +C + E ++ P L+ N D+ L G Q+ + + + Q + CA E++ Q L+D+ + +++T + + SG +L + N+ + FVW++ F D + AK G+ + SE F T KNG+K+ ++YP+G GK H+S F + +GE+DGIL WPF + L++Q+
Sbjct: 11 YDSEFVIAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDREP-----LDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTC--SNPMCSA-QLPRMDVDEHLLVE--CDWRLIVCEYCGDESPYCLQKAHARNCDYKLVTCSNPMCSAQLP----RMDVDEHLLVECDWRLIVCEYCGDESPYCLQKDHSNQCDKFPVLCPNDCGTQITREKLRDHQSEECQFAVVPCAFRDFGCEVEIQNRLMDQHLDTNIQSHLNMTCNQLLLSRDSGAQFHELQQGLGRVNELLKMRFVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQK 404
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 114.775 bits (286), Expect = 5.013e-27 Identity = 125/479 (26.10%), Postives = 204/479 (42.59%), Query Frame = 2
Query: 128 SMKSYDYETI-GEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC---PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLL----MDFVVNFNNEMEILKANNNGLSPVN------ELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEI---KQKELIDKIGQMENKQKVDLTEMSNKIDKL--------SGNVDRKL----LEMAAN--QNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLD-YELDIDGDAFCKPVSKCGSEFGFHQFISHRDLS 1468
+M Y+ T I + LC C+ ++ +A CG R+C C+S L P + C I+ E D+ + +I +L V C P C ++ ELR ++H C + C + G +S K+ +HLQ+E + VV M+ PVN EL+R E++ + R +E G R C N E +E I L + ++GLQ + + A+ D +++A E+ + +D++ + + V L E + I +L G R L LE N Q + +WK+ +K ++A +G YS F T +G+KMC +Y +GDG G+ +H+S+FF +M+GEFD +L WPFR VT L++Q + H +D + D +F +P ++ G F SH L+
Sbjct: 5 AMVGYEIATTDTAIAAKHLCAKCRLIVKDAVQTACGHRYCSPCISPLLSRG---PIQCDVCG-STITKPETFR-DKFADREILELHVHCVNQPHG-CPWEGELRHRQNHHTKCEFNPISCVHPECGK---KLSVAKLPEHLQNECQYREETCSYCEQPVVVA---RMKEHHEKTCPSYPVNCPKCSKELIRVEVHSTPFTREPR-LEKG---RGCENTLEVLEDHESRIKKLEQRGGGIG--VNGLQSMRISENIDNEAI-GDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQ-DNVEHV---IDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLT 460
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Match: EDO37750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SER6]) HSP 1 Score: 107.071 bits (266), Expect = 1.679e-24 Identity = 111/461 (24.08%), Postives = 199/461 (43.17%), Query Frame = 2
Query: 155 IGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCP--EVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEM--EILKANNNGLSPVNELLRNEINELKLDGDRRRVE--IGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDR-LDGLQLIIEGN----QVAMRAVE----NDFQQQIAQCA---TNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRT-RLAHFSGDLDYELDIDGDAFCKPVSKCGS-EFGFHQFISHRDLSA 1471
+ + + +LC +C + NA + CG RFC C++ L E R CP D I ++ + D N I L V C + C+++ +LRK++ H+ C + S+ C S C I + ++++H + + E L+ N G L+ + + + G+R RV+ ++ C N+ + N +I R DR + L N Q+ VE D + I QC C + + Q+ L I + + ++E++ + K + L E+ + + + +W++D F + + K ++S F T G+K + ++P G+G G+G HLS++ L+ GE+D +L WPF +T L++Q T + A + D + +F +P S FG+ QF+SHR L +
Sbjct: 9 VPAVRENLLCRICHLPVRNAVQVSVCGHRFCDSCLNHALGETRLRCPVDNT-----AIDYSQ-VYADDVTNQMIMSLTVICDYYQAGCKWKGQLRKLQGHLAECKFVSADCSNS---CGA-RIQKRRMSEHTSKDCPKRRVCCARCKAEMSYEQLRVSLRYRNEG-----ALVSDHVTCPRNCGERMRVQDKARHMREDCLNRWVFCQYCNTEI-VFR--DRQTHHQSCPSFPLSCPNNCGVAQIPRGEVELHLSRDCRSNIMQCPFRHVGCHK-QFPQRSLQRHIEESVQQHLELVSELAIQQQKEINS----LKEIVRHCKPYHDSKLLWRIDDFWEAFDEGKRKPGTELHSPVFYTSNYGYKFKVVLFPYGNGSGEGTHLSLYIRLLPGEYDSLLPWPFEGQITLTLLDQSTDKRAKRHISQSFSPDPNWKSFQRPSKNSTSLGFGYPQFVSHRGLES 446
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 130.568 bits (327), Expect = 2.539e-31 Identity = 101/361 (27.98%), Postives = 169/361 (46.81%), Query Frame = 2
Query: 428 KMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIG-----DLQRKCANQ-AEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIK-----------QKELIDKIGQME--NKQ------KVDLTEMSNKIDKLSGNV---DRKLLEMAANQN----QRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVS 1414
K DHI+ C+ + C + +GCD ++ ++K+ DH + + H LL+ F++ +E L+ L ++ L +E+++ D + R ++G LQ CA A L+ + A L+L ++ + ++A+ + CQ+ E+K +EL ME N+Q K+++ +SNK+ +L V D ++EM +G F+WK+ FT K DA G ++S +F T K G+KMCL +Y +GDG G+G HLS+FF +M+G D +L+WPF VT L++Q R + DI +F +PVS
Sbjct: 202 KYVDHIKFCSKFKAPCRFHVVGCDT-SVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQR--LEVASQKL-HELHQSLRDLELRMSQLGRSGTAPLQGVCAATLATSFTPLHSAMGA-------------ALELQLQSEKT-----------KVAELSRRCQELELKVSTFENIVCILNRELERSCATMEAYNRQHRLDQDKIEI--LSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIIDA---FRPDISSSSFQRPVS 529
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 123.25 bits (308), Expect = 1.765e-29 Identity = 107/439 (24.37%), Postives = 189/439 (43.05%), Query Frame = 2
Query: 167 EDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL-CENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVL--CEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSAN 1474
E + C C+ +L CG RFC+ C+++ L C N CP D E + I D + +I L V C C+ Q L+++ DH+ +C + CP +G K + + ++ +HL + + + +F N E+ K N L + + ++ E++ L ++ +L R + D ++ L+ ++ + + A+E Q + +++ M + ++ L +M + ++LE A+ NG +WK+ + + DA G +YS+ F T G+KMC VY +GDG GKG HLS+FF +M+GE+D +L WPF+ VT L++Q H GD ++ D +F +PV++ G F+S L +
Sbjct: 43 EAKYCCEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPADMEPL------FKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCP---LGKCKERMMRKEIPEHLAWKC-KYRESTCEFCKNKMPLTELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLM---------SSHTEKLLELELELRSL----RQLRDEMESLRGTLDTVRTRLSALE--------------QGGRASLETQLNRHDDMLSVHEIRLADMDLRF---------QVLETAS-----YNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHL-GDA-FKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESG 428
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 122.479 bits (306), Expect = 3.942e-29 Identity = 111/475 (23.37%), Postives = 213/475 (44.84%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNI--SQDKVTDHLQSEIFVHTKLLMDFVVN-FNNEMEILKANNNGLSPVNELL-RNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIE-GNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + C LC K + + CG RFC C+ E+L E + CP D +L I D + +I L ++C E C + ++++++ H C + CP ++C++ ++ + DHLQ + K+ +F + F E N+ G+ P + N+ + RR+ +C + + + ++ D + + + ++ NQ +A + N + C + K K+ +E+ K LT M N + + + R++ E++ + + G +WKL+ ++ K+ +AK N +S F TH+ G+K+ +S + +G+G G+G+HLSV+ ++ GE+D +LEWPF + VTF++++Q ++ H + + D + F KP S S FG+ +FISH ++
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCP------NRCSVKLTRRDLPDHLQHDC-PKRKVKCEFCGSEFTGEA---FENHQGVCPQESVYCENKCGARMM----RRLLSQHGMAECPKRTQPCKYCGKEF----VFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSRQRQEILELRREMEELSVSHD----GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITE--TFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 122.479 bits (306), Expect = 5.552e-29 Identity = 111/475 (23.37%), Postives = 213/475 (44.84%), Query Frame = 2
Query: 131 MKSYDYETIGEIEDEMLCLLCKKLLVNA-HSAPCGCRFCFVCVSEYLCENRY-CPGDTEDCKLELISITENIMVDRPMNVKISKLLVKC--PEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNI--SQDKVTDHLQSEIFVHTKLLMDFVVN-FNNEMEILKANNNGLSPVNELL-RNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIE-GNQ-----VAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIG---QMENKQKVDLTEMSNKIDKLSGNV---DRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQR----TRLAHFSGDLDYELDIDGDAFCKPVSKCGS------EFGFHQFISHRDL 1465
M +DY+ + + + C LC K + + CG RFC C+ E+L E + CP D +L I D + +I L ++C E C + ++++++ H C + CP ++C++ ++ + DHLQ + K+ +F + F E N+ G+ P + N+ + RR+ +C + + + ++ D + + + ++ NQ +A + N + C + K K+ +E+ K LT M N + + + R++ E++ + + G +WKL+ ++ K+ +AK N +S F TH+ G+K+ +S + +G+G G+G+HLSV+ ++ GE+D +LEWPF + VTF++++Q ++ H + + D + F KP S S FG+ +FISH ++
Sbjct: 1 MPGFDYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPED------QLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCP------NRCSVKLTRRDLPDHLQHDC-PKRKVKCEFCGSEFTGEAF---ENHQGVCPQESVYCENKCGARMM----RRLLSQHGMAECPKRTQPCKYCGKEF----VFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSRQRQEILELRREMEELSVSHD----GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITE--TFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEI 445
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Match: ENSORLT00000001369.2 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:101170323]) HSP 1 Score: 110.923 bits (276), Expect = 6.379e-25 Identity = 118/525 (22.48%), Postives = 226/525 (43.05%), Query Frame = 2
Query: 122 WESMKS---YDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITEN-IMVDRPMNVKISKLLVKCP-EVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQS------EIFVH------TKLLMDFVVNFNNEMEILKANN-NGLSPVNELLRN--EINELKLD-----------GDRRRVEIGD------------------------LQRKCANQAEEIEL-------LNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQ-KELIDKIGQ---MENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQ-------RINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGS--EFGFHQFISHRDLSA 1471
WES + + + + ++++E +C +CK +++N CG +CF C+ + L E+ G C +E +IT + + D +IS L V C LC L ++++H++ C Y+ C SN GC + + + + +HL + E H ++ D V + E+++ + + L P N L + E+ D G RR+V++ + +Q++ + +E++ L E + ++ R+ + Q + + A+ +V+ D QQ C E+++ K +D + Q + + + + SG ++ + ++A N+ +G +WK+ F + G + + S F T + G+KM + Y +GDG G+G HLS++ LM G+FD +L WPF+ +V+ ++++Q H S ++ D F +P ++ S GF FIS L A
Sbjct: 45 WESELASLQHSLKFVMKLKEEFICPICKGVVLNPQQNSCGHIYCFHCL-QGLLESSLLSGPV--CPVEKAAITPSEVFQDNCCKREISSLEVYCTNSPLCTSVLALNQLQEHLKSCQYEQLLC--SNPGCTEL-LQRRLLQEHLNATCPHRRESCPHCLQPFQLSVIQDHVQSSCPEVKVGCPDGCSTLVPRNRLTEHGESCPEVHTDCSFKMFGCSVKGKRRKVKLHEEAAVCHHVLLVLKSSAHLEQQVVFVQKEALLRQQEVQTDTLLLSDLQEQLGSVLQQSRSQEHIVATAQRTLSRQEDALSSVQLDLQQ--VSCGMGSGLDELRRFKTSLDGVMQELLAAETLREHIATLEENRKRHSGLLELHVAQLALNKQHLQELELTSYDGRLIWKIKDFQKRREAEATGQHPCLSSVPFHTGRCGYKMAMKAYLNGDGEGRGTHLSLYVVLMPGDFDALLPWPFKQTVSLSVLDQSGARNHQS--FNFRPDPTNTCFHQPAAESASNVAVGFPCFISLDALEA 559
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Match: SMESG000025980.1 (SMESG000025980.1) HSP 1 Score: 743.421 bits (1918), Expect = 0.000e+0 Identity = 373/462 (80.74%), Postives = 409/462 (88.53%), Query Frame = 2
Query: 101 ATKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL-CENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
+KLEN+ + M+ Y+YE++ EI+++MLCLLCKKLLVNA APC CRFCF C+S++L + + CPG+TE+CK E++ + ENI VD PMN+KI+KL VKC E+ C++ ELRKMEDH R C Y+S CPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEF+WKLDKFTDKMADAK GINA IYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRL H S + + F +P + GF +F+SH +LS+NP+L
Sbjct: 3 GSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDFLDHKKKNCPGNTEECKQEMLHLNENICVDYPMNMKIAKLQVKCKEMSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKKGINAFIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKITECANYPNNKEFIQPTDRNAGR-GFARFVSHEELSSNPDL 463
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Match: SMESG000025794.1 (SMESG000025794.1) HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0 Identity = 338/462 (73.16%), Postives = 376/462 (81.39%), Query Frame = 2
Query: 101 ATKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL-CENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
+KLEN+W+ M+ Y+YE++ EI+++MLC LCKKLLVNA APCGCRFCF C+S++L + + CPGDTE+CK E++ + ENI VD PMN+KISKL VKC E+ C + ELRKMEDH R C Y+S CPYSNIGCDKCNISQDKVTDHLQSEIF HTKLLMDFVVNFNNEME+LKANNNGLS VNELLRNEINELKLDG+RRRVEI DLQRKCA+QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEF+WKLDKFTDKMADAKNGIN IYSESFLTHKNGFKMCL V PDG+GGGKG HLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRL H S + + A +P + + GF +F+SH +LS+NP+L
Sbjct: 3 GSKLENVWQIMRDYNYESVTEIQNDMLCFLCKKLLVNARCAPCGCRFCFTCISDFLDHKEKICPGDTEECKQEMLHLNENICVDYPMNIKISKLQVKCKEMSCVYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRVEIADLQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKNGINTRIYSESFLTHKNGFKMCLRVDPDGNGGGKGTHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKTVKCANYPNDKALIQPTDR-NAGLGFPKFVSHEELSSNPDL 435
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Match: SMESG000025982.1 (SMESG000025982.1) HSP 1 Score: 672.544 bits (1734), Expect = 0.000e+0 Identity = 346/462 (74.89%), Postives = 381/462 (82.47%), Query Frame = 2
Query: 101 ATKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYL-CENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
+KLEN+ + M+ Y+YE++ EI+++MLCLLCKKLLVNA APC CRFCF C+S++L + + CPG+TE+CK E++ + ENI VD PMN+KI+KL VKC E+ C++ ELRKMEDH R C Y+S CPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAK GINA IYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRL H S + + F +P + GF +F+SH +LS+NP+L
Sbjct: 3 GSKLENVGQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDFLDHKKKNCPGNTEECKQEMLHLNENICVDYPMNMKIAKLQVKCKEMSCDYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKKGINAFIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKITECANYPNNKEFIQPTDRNAGR-GFARFVSHEELSSNPDL 435
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Match: SMESG000025934.1 (SMESG000025934.1) HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0 Identity = 334/402 (83.08%), Postives = 364/402 (90.55%), Query Frame = 2
Query: 101 ATKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRRVEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRH 1306
+KLEN+W+ M+ Y+YE++ EI+++MLCLLCKKLLVNA APC CRFCF C+S+YL +N CPG+TEDCK E++ + ENI VD+PMN+KISKL VKC E+ C++ ELRKME+H R C Y+S CPYSNIGCDKCNISQDKVTDHLQSEIF HTKLLMDFVVNF+NEME+LKANNNGLS VNELLRNEINELKLDG+RRR EI +LQ KCA+QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDK SGNVDRKLLEMAANQNQRINGEF+WKLDKFTDKMADAK GINAIIYSESFLTHKNGFKMCL V PDGDG GKG HLSVFF LMKGEFDGILEWPF H
Sbjct: 3 GSKLENVWQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQEVLYLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRACKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFHNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELQMKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKSSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKKGINAIIYSESFLTHKNGFKMCLRVDPDGDGVGKGTHLSVFFCLMKGEFDGILEWPFSH 404
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Match: SMESG000025901.1 (SMESG000025901.1) HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0 Identity = 342/495 (69.09%), Postives = 379/495 (76.57%), Query Frame = 2
Query: 104 TKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFVCVSEYLCENRYCPGDTEDCKLELISITENIMVDRPMNVKISKLLVKCPEVLCEFQSELRKMEDHIRMCNYQSSQCPYSNIGCDKCNISQDKVTDHLQSEIFVHTKLLMDFVVNFNNEMEILKANNNGLSPVNELLRNEINELKLDGDRRR-----------------------------------VEIGDLQRKCANQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGNQVAMRAVENDFQQQIAQCATNCQQAEIKQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGDGGGKGNHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLAHFSGDLDYELDIDGDAFCKPVSKCGSEFGFHQFISHRDLSANPEL 1483
+KLEN+W+ M+ Y+YE++ EI+++MLCLLCKKLLVNA APC CRFCF C+S+YL +N CPG+TEDCK E++ + ENI VD+PMN+KISKL VKC E+ C++ ELRKME+H R C Y+S C YSNIGCDKCNISQDKV DHLQSEIFVHTKLLMDFVVNFNNEME+LKANNNGLS VNELLRNEINELKLDG+RRR VEIGDLQRKCA+QAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDG G GKG HLSV+FHLMKGEFDGILEWPFRHSVT ALINQRTRL H S Y D + +P + + GF +F+SH +LS+NP+L
Sbjct: 4 SKLENVWQIMRDYNYESVTEIQNDMLCLLCKKLLVNARCAPCSCRFCFTCISDYLDKNEICPGNTEDCKQEVLHLNENIYVDQPMNIKISKLQVKCKEMSCDYVDELRKMEEHSRTCKYRSEACLYSNIGCDKCNISQDKVEDHLQSEIFVHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRREEIAELRVNIICLNGENAAMRENMDKLISAGERNQVEIGDLQRKCADQAEEIELLNEDIPALRNVDRNVSDRLDGLQLIIEGN----------------------------QKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFVWKLDKFTDKMADAKNGINAIIYSESFLTHKNGFKMCLSVYPDGVGVGKGTHLSVYFHLMKGEFDGILEWPFRHSVTLALINQRTRLPHVSETTKYANDSNSKTLIQPTDR-NAGLGFPKFVSHEELSSNPDL 469 The following BLAST results are available for this feature:
BLAST of TNF receptor associated factor 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor associated factor 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor associated factor 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor associated factor 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032941 ID=SMED30032941|Name=TNF receptor associated factor 4|organism=Schmidtea mediterranea sexual|type=transcript|length=2232bpback to top protein sequence of SMED30032941-orf-1 >SMED30032941-orf-1 ID=SMED30032941-orf-1|Name=SMED30032941-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=479bp MATKLENIWESMKSYDYETIGEIEDEMLCLLCKKLLVNAHSAPCGCRFCFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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