Peptidase S1 domain-containing protein

Overview
NamePeptidase S1 domain-containing protein
Smed IDSMED30032940
Length (bp)1352
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Peptidase S1 domain-containing protein (SMED30032940) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30032940) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidase S1 domain-containing protein (SMED30032940) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30032940) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30032940

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30032940h1SMcG0011347 dd_Smed_v4_2566_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30032940h1SMcG0011347 dd_Smed_v4_2566_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30032940h1SMcG0011347 dd_Smed_v4_2566_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 102.834 bits (255), Expect = 4.086e-23
Identity = 93/310 (30.00%), Postives = 132/310 (42.58%), Query Frame = 2
Query:   80 IAFIFCVTCTHSS-MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +  + C  C H      RI+GG  +   ++ W  S++     L     CG S++ TP   LW++TAAHC        VY+L   K W  +VGL                   V  L N A   L              + KI+ H  Y+P          R+ NDIALMKL  PL  +++  +  + LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYL      C GDSG  L+C  +    + G  S G G      P V++RV++F +WI
Sbjct:  199 VVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHL-----CGGSVI-TP---LWIITAAHC--------VYDLYLPKSWTIQVGL-------------------VSLLDNPAPSHL--------------VEKIVYHSKYKPK---------RLGNDIALMKLAGPLTFNEM--IQPVCLPNSEEN--FPD-GKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 443          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 102.834 bits (255), Expect = 4.086e-23
Identity = 93/310 (30.00%), Postives = 132/310 (42.58%), Query Frame = 2
Query:   80 IAFIFCVTCTHSS-MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +  + C  C H      RI+GG  +   ++ W  S++     L     CG S++ TP   LW++TAAHC        VY+L   K W  +VGL                   V  L N A   L              + KI+ H  Y+P          R+ NDIALMKL  PL  +++  +  + LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYL      C GDSG  L+C  +    + G  S G G      P V++RV++F +WI
Sbjct:  199 VVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHL-----CGGSVI-TP---LWIITAAHC--------VYDLYLPKSWTIQVGL-------------------VSLLDNPAPSHL--------------VEKIVYHSKYKPK---------RLGNDIALMKLAGPLTFNEM--IQPVCLPNSEEN--FPD-GKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 443          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 102.834 bits (255), Expect = 4.337e-23
Identity = 93/310 (30.00%), Postives = 132/310 (42.58%), Query Frame = 2
Query:   80 IAFIFCVTCTHSS-MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +  + C  C H      RI+GG  +   ++ W  S++     L     CG S++ TP   LW++TAAHC        VY+L   K W  +VGL                   V  L N A   L              + KI+ H  Y+P          R+ NDIALMKL  PL  +++  +  + LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYL      C GDSG  L+C  +    + G  S G G      P V++RV++F +WI
Sbjct:  197 VVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHL-----CGGSVI-TP---LWIITAAHC--------VYDLYLPKSWTIQVGL-------------------VSLLDNPAPSHL--------------VEKIVYHSKYKPK---------RLGNDIALMKLAGPLTFNEM--IQPVCLPNSEEN--FPD-GKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 441          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 98.9821 bits (245), Expect = 9.805e-22
Identity = 86/314 (27.39%), Postives = 127/314 (40.45%), Query Frame = 2
Query:   80 IAFIFCVTC---THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            +  + C+ C    +SS + RI+GGE A P  + W VS+      ++    CG SI+ TP    W+VTAAHC           L    +W A  G+ +  F++   G +                                + K+I HP Y    K         +NDIALMKL++PL  + L  V  + LPN  +      +   C + GWG T+ K   + +   A + +     C +       I PA   CAG+L+     C GDSG  L+        + G  S G G      P V+  V  F +WI+R
Sbjct:  236 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH-----VQNVHVCGGSII-TPE---WIVTAAHCVEKP-------LNNPWHWTAFAGILRQSFMFYGAGYQ--------------------------------VEKVISHPNYDSKTK---------NNDIALMKLQKPLTFNDL--VKPVCLPNPGMMLQPEQL---CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM-ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYR 486          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 98.9821 bits (245), Expect = 9.805e-22
Identity = 86/314 (27.39%), Postives = 127/314 (40.45%), Query Frame = 2
Query:   80 IAFIFCVTC---THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            +  + C+ C    +SS + RI+GGE A P  + W VS+      ++    CG SI+ TP    W+VTAAHC           L    +W A  G+ +  F++   G +                                + K+I HP Y    K         +NDIALMKL++PL  + L  V  + LPN  +      +   C + GWG T+ K   + +   A + +     C +       I PA   CAG+L+     C GDSG  L+        + G  S G G      P V+  V  F +WI+R
Sbjct:  236 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH-----VQNVHVCGGSII-TPE---WIVTAAHCVEKP-------LNNPWHWTAFAGILRQSFMFYGAGYQ--------------------------------VEKVISHPNYDSKTK---------NNDIALMKLQKPLTFNDL--VKPVCLPNPGMMLQPEQL---CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM-ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYR 486          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 76.2554 bits (186), Expect = 1.580e-14
Identity = 76/301 (25.25%), Postives = 126/301 (41.86%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARV-GLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPA-SDFCAGYLKKKYGLCHGDSGSGLICDYQ-GTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVIS 1021
            R++GG E  P  + W  +++   +K   +  CGASIL        L+TAAHCF   + V+ Y +  G + + +  G  ++ +L + H             F   Y+ +F  D   +          I +PG                  I   +  +P+ +     V T G                C+V GWG   ++ A     + A++ I +  +C NS  S++Y + + S FCAGYL+     C GDSG    C  + G   +AGV+S G G      P +++ V+ +  WI  +I+
Sbjct:  712 RVVGGFETVPGAFPWTAALR---NKATKAHHCGASILDK----THLITAAHCFEEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIH-------------FYPLYKDIFSHDIAILE---------IPYPG------------------IEFNEYAQPICLPSKDFVYTPG--------------RQCVVSGWGSMGLRYAER--LQAALIPIINRFDCVNS--SQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISAIIN 947          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-1 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q23528])

HSP 1 Score: 70.0922 bits (170), Expect = 3.759e-13
Identity = 78/300 (26.00%), Postives = 120/300 (40.00%), Query Frame = 2
Query:  116 SMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSD-CIVVGWGCT-KVKNAPNPIAKLAILKIWSNSECENSVPSKL-YINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +++ R+IGG E+ P  + W V +   +   +    CG S++  P  VL   TAAHCF      T Y++  G +                           +S     +R                ++ + IHP Y           F    D A+M++  P  ++  +    I LP      S PA+ +  C+V GWG T +  +   P  +   + + S   C +S+P+ +  I+  S  CAGY   K   C GDSG  L+C   G   + GVVS G G    G P V+  V +   WI
Sbjct:   53 TLDHRLIGGSESSPHSWPWTVQLLSRLGHHR----CGGSLID-PNFVL---TAAHCFAKDRRPTSYSVRVGGH---------------------------RSGSGSPHR----------------VTAVSIHPWYNIG--------FPSSYDFAIMRIHPP--VNTSTTARPICLP------SLPAVENRLCVVTGWGSTIEGSSLSAPTLREIHVPLLSTLFC-SSLPNYIGRIHLPSMLCAGYSYGKIDSCQGDSGGPLMCARDGHWELTGVVSWGIGCARPGMPGVYGNVHSASTWI 284          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: mas (gene:FBgn0011653 transcript:FBtr0073260)

HSP 1 Score: 94.3597 bits (233), Expect = 4.016e-20
Identity = 89/306 (29.08%), Postives = 141/306 (46.08%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTK-GKYWHARVGLTKVDF-LYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPI-AKLAILKIWSNSEC---ENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            R++GGE+    ++ W V++  ++++      CGA+++ T     W++TAAHC        V N+ + G   + RVG    D+ L +K+G                     G    +V T  +H                ++     +DNDIAL+KL     +    GV  + LP   V+    A G  C V G+G    +  P P+  + A + I S++EC    N+V  K++I PAS FCAG  ++ +  C GD G  L+C   G   +AG+VS G G      P V+ + S+F  WI ++IS N
Sbjct:  802 RVVGGEDGENGEWCWQVALINSLNQY----LCGAALIGT----QWVLTAAHC--------VTNIVRSGDAIYVRVG----DYDLTRKYGSP-------------------GAQTLRVATTYIH----------------HNHNSQTLDNDIALLKLHGQAELRD--GVCLVCLPARGVSH---AAGKRCTVTGYGYMG-EAGPIPLRVREAEIPIVSDTECIRKVNAVTEKIFILPASSFCAGG-EEGHDACQGDGGGPLVCQDDGFYELAGLVSWGFGCGRQDVPGVYVKTSSFIGWINQIISVN 1045          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: mas (gene:FBgn0011653 transcript:FBtr0332659)

HSP 1 Score: 93.9745 bits (232), Expect = 4.472e-20
Identity = 89/306 (29.08%), Postives = 141/306 (46.08%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTK-GKYWHARVGLTKVDF-LYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPI-AKLAILKIWSNSEC---ENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            R++GGE+    ++ W V++  ++++      CGA+++ T     W++TAAHC        V N+ + G   + RVG    D+ L +K+G                     G    +V T  +H                ++     +DNDIAL+KL     +    GV  + LP   V+    A G  C V G+G    +  P P+  + A + I S++EC    N+V  K++I PAS FCAG  ++ +  C GD G  L+C   G   +AG+VS G G      P V+ + S+F  WI ++IS N
Sbjct:  801 RVVGGEDGENGEWCWQVALINSLNQY----LCGAALIGT----QWVLTAAHC--------VTNIVRSGDAIYVRVG----DYDLTRKYGSP-------------------GAQTLRVATTYIH----------------HNHNSQTLDNDIALLKLHGQAELRD--GVCLVCLPARGVSH---AAGKRCTVTGYGYMG-EAGPIPLRVREAEIPIVSDTECIRKVNAVTEKIFILPASSFCAGG-EEGHDACQGDGGGPLVCQDDGFYELAGLVSWGFGCGRQDVPGVYVKTSSFIGWINQIISVN 1044          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: tpr (gene:FBgn0034661 transcript:FBtr0071743)

HSP 1 Score: 90.1225 bits (222), Expect = 2.145e-19
Identity = 89/310 (28.71%), Postives = 126/310 (40.65%), Query Frame = 2
Query:   95 CVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGA--CGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDYQGTP--TIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            CV C  ++++KRI+GG+E    +Y W       V  L   G   C AS+L       +L+TA+HC Y                                G +   KE++     +  RK+    K      D  ++++I HP Y              DNDIA++KL EP+  +++     +  P  S        G + IV GWG  KV    +   +   + I S  EC  S     Y N  +D   C GY +     C GDSG  L     GT    IAGVVS G G    GYP V++RV+ +  WI
Sbjct:  116 CV-CGIANIQKRIVGGQETEVHQYPW-------VAMLLYGGRFYCAASLLNDQ----FLLTASHCVY--------------------------------GFR---KERISVRLLEHDRKMSHMQKI-----DRKVAEVITHPKYNAR---------NYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFK------GENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKS----RYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG6041 (gene:FBgn0029826 transcript:FBtr0070861)

HSP 1 Score: 85.5001 bits (210), Expect = 3.599e-18
Identity = 81/309 (26.21%), Postives = 129/309 (41.75%), Query Frame = 2
Query:  107 THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGA---CGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDL---HISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNA-PNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            T   +E +I+GG +A  ++  + VSI+   +  K  G+   CG  ++    Q L + TAAHC Y +D                               K K++   + +       + G      +TD     ++ ++I H  Y P           + NDIALM +   +P +  + V+ + L     NS   A  +DC++ GWG  +      +   + A + I S + C  S  S     P S  CAGYL      C GDSG  + C+      +AG+VS G G    GYP V++ VS + +WI +
Sbjct:   27 TAGKIEPKIVGGYDASIEQVSYQVSIRLTANDKKSYGSGHLCGGVVIS---QRL-VATAAHCCYITD-------------------------------KKKYRTAGEFVL------VMGSTYLTSSTDRTLMYYLQQLITHENYNPDA---------LTNDIALMFINGYIPWNWPT-VTALAL-----NSQLVATNTDCLISGWGLLQQNGTFSSNTLQAATVPIVSYTTCRISYNSI----PVSQVCAGYLSGGVDACQGDSGGPMSCN----GMLAGIVSYGAGCAAPGYPGVYTNVSYYYDWIVQ 271          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG11836 (gene:FBgn0039272 transcript:FBtr0309271)

HSP 1 Score: 80.4925 bits (197), Expect = 1.149e-16
Identity = 89/331 (26.89%), Postives = 131/331 (39.58%), Query Frame = 2
Query:   26 ELEFSEFTKMKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISK----IIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            E+E++E + +KN              C  S+ E RI+GG+    ++Y W   I   V   K    CG S+L       ++++AAHC                                           VK L     R +FG    ++T++   I +    +I H  + P            +NDIAL++L++P+   ++  +  I LP ++ +   PA G    VVGWG T        I     + I S +EC N       I  +S  CAG  +     C GDSG  L+        I G+VS G G    GYP V+SRVS F  WI
Sbjct:   20 EVEYTENSSLKNCD----------CDCGFSNEEIRIVGGKPTGVNQYPWMARI---VYDGKFH--CGGSLLTKD----YVLSAAHC-------------------------------------------VKKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDT---------YNNDIALLRLRKPISFSKI--IKPICLPRYNYD---PA-GRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRIT-SSMLCAG--RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWI 270          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: CU062628.1 (trypsin-2-like [Source:NCBI gene;Acc:103908930])

HSP 1 Score: 107.842 bits (268), Expect = 1.995e-26
Identity = 93/325 (28.62%), Postives = 145/325 (44.62%), Query Frame = 2
Query:   53 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            MK  ++  L+  + C      S   +IIGG E PP+   W + I  +  +      CGAS++       W V+AAHC   ++ +TVY           +G   +D +       +K ++++++       K+F   +FK  ++                           DNDI L+KLK+P   +Q   V  I L      +S  + G  C+V GWG T+V   P+ +  L  L + S  ECE     K   N     CAG+++   G+CHGDSG  L+C+ +    + GVVS G G    GYPAV+  V  + +WI   I++N
Sbjct:    1 MKTVVFALLVVNVAC------SPVDKIIGGYECPPNSQPWQIYITNDGQRW-----CGASLINES----WAVSAAHCNIGANLLTVY-----------LGKHNIDVV-------EKTEQRIRT------EKVFPHPEFKFPSE---------------------------DNDIMLIKLKDPAVFNQY--VQPIPLA-----TSCSSEGEQCLVSGWGYTEV-GLPSVLQCLD-LAVQSRQECERVYKDKFTQNM---LCAGFMEGGKGVCHGDSGGPLVCNGE----LRGVVSWGAGCAEPGYPAVYVEVCRYSDWIATTIANN 243          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:92590 (zgc:92590 [Source:ZFIN;Acc:ZDB-GENE-041024-15])

HSP 1 Score: 95.1301 bits (235), Expect = 7.998e-22
Identity = 83/318 (26.10%), Postives = 140/318 (44.03%), Query Frame = 2
Query:   77 LIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +I F   V     S + +IIGG E  P+   W + +  +  +      CGAS++       W V+AAHC+  ++ +TV+           +G   V        +++  ++++K+                         K+I HP Y      ND   + +DND  L+KLKEP   +Q   V  I L      +S  + G  C+V GWG         P + +   L + + ++CE +   ++  N    FCAG+++     C GDSG  +IC+ +    + GVVS G+G    GYP V++ V  + +W+   I++N
Sbjct:    3 MIVFALLVLAVACSADDKIIGGYECSPNSQPWQIYLTYDNGQRW----CGASLIND----RWAVSAAHCYLVANRLTVH-----------LGEHNV-------AVEEGTEQRIKA------------------------EKVIPHPKY------ND---YTLDNDFMLIKLKEPAVFNQY--VQPIPL-----TTSCSSEGEQCLVSGWGNLINTGVVYPDVLQCLNLPVLTRAQCEGAYGWQITKNM---FCAGFMEGGKDACQGDSGGPVICNGE----LRGVVSWGYGCADSGYPGVYTEVCRYTDWVASTIANN 247          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: CR352265.1 (pep chromosome:GRCz11:24:21813127:21819010:-1 gene:ENSDARG00000062758.6 transcript:ENSDART00000091096.6 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR352265.1)

HSP 1 Score: 93.9745 bits (232), Expect = 5.250e-21
Identity = 79/311 (25.40%), Postives = 132/311 (42.44%), Query Frame = 2
Query:   89 IFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDYQGTP-TIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            + C   T      +I+GG +A    + W VS++      +    CGAS++ +     WLV+AAHCF  SD +     +  + W A +G+  ++                 S+ N A  +               I +I++H  Y           F  D DIAL++L  P+  ++L     +  P+    S     G+ C V GWG    +     + + A + I +++ C     +K+Y +  +    CAG ++     C GDSG  L+C  +G    +AG+VS G G      P V++RV  F +WI +
Sbjct:   41 LRCGCGTRPRKRAKIVGGTDAQAGSWPWQVSLQME----RYGHVCGASLVAS----RWLVSAAHCFQDSDAI---KYSDARSWRAYMGMRVMN-----------------SVSNAAATR--------------QIRRIVLHSQYD---------QFTSDYDIALLELSAPVFFNELVQPVCVPAPSHVFTS-----GTSCFVTGWGVLTEEGELATLLQEATVNIINHNTC-----NKMYDDAVTPRMLCAGNIQGGVDACQGDSGGPLVCLERGRRWFLAGIVSWGEGCARQNRPGVYTRVIKFTDWIHQ 290          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: tmprss9 (transmembrane serine protease 9 [Source:ZFIN;Acc:ZDB-GENE-050208-573])

HSP 1 Score: 95.9005 bits (237), Expect = 1.242e-20
Identity = 88/308 (28.57%), Postives = 129/308 (41.88%), Query Frame = 2
Query:   92 FCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTK--VKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDY-QGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            FC   T   M  RI+GGE     ++ W VS++     L+    CGASI+ +     WLV+AAHCF   +          K W A VG  +V          + F   +KSL                          ++ P Y P            D+D+ +++L+ PL       V  + +P+   +S     G +CIV GWG         P+ + K AI+KI  +  C  S   +  +   +  CAG+L+ K   C GDSG  L C+   G   +AG+VS G G      P V+SRV+  + WI
Sbjct:  219 FCSCGTRPVMSNRIVGGENTRHGEFPWQVSLR-----LRGRHTCGASIVNS----RWLVSAAHCFEVEN--------NPKDWTALVGANQV-----SGAEAEAFIVNIKSL--------------------------VMSPKYDP---------MTTDSDVTVLELETPLKFSHY--VQPVCIPS---SSHVFTPGQNCIVSGWGALNQYTTEVPSTLQK-AIVKIIDSKVCNKSSVYRGALT-QNMMCAGFLQGKVDSCQGDSGGPLACEVAAGRYFLAGIVSWGVGCAQINKPGVYSRVTKLRNWI 462          

HSP 2 Score: 86.2705 bits (212), Expect = 1.530e-17
Identity = 74/298 (24.83%), Postives = 125/298 (41.95%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAI--GSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLIC-DYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            ++RIIGG  A   ++ W  S++      +    CGA+++       WL+TAAHCF        Y ++ G    + +G   +                                          + +II HP +  +          MD D+AL+++  P P  +   + T+ LP     S W +     +C ++GWG  +       + + A + +   S+C+ +  ++L  N     CAGY++ +   C GDSG  L+C +  G   +AGV S GHG    G+P V+ R +A +EWI
Sbjct:  554 QERIIGGVTARRGEWPWVGSLQ-----YQRIHRCGATLIHCK----WLLTAAHCFRGDLNPAGYTVSLGSVIWSGLGALVIP-----------------------------------------VQRIIPHPAFNSST---------MDLDVALVEISIPAP--KSYTIQTVCLP-----SPWHSFIKSMECYIIGWGAVREDGMITNLLQKAQVGVIDQSDCQRAYGAELTDNM---MCAGYMEGQRDTCLGDSGGPLVCRETLGRWFLAGVTSWGHGCGRIGFPGVYMRATAVREWI 782          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zmp:0000001114 (zmp:0000001114 [Source:ZFIN;Acc:ZDB-GENE-140106-74])

HSP 1 Score: 95.9005 bits (237), Expect = 1.455e-20
Identity = 92/315 (29.21%), Postives = 127/315 (40.32%), Query Frame = 2
Query:   95 CVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSG-ACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSEC----ENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTI-AGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVIS 1021
            C   T      RI+GG+ A   ++ W VS+       K  G ACGASI+       WL+ AAHCF   D    Y +T    W    GL   +   +   M+D                               +  II HP Y      ND      D DI+L++L +PL       V  I LP     S     GS C V GWG  +   +   I + A +K+ +++ C    E  V S++        C+GYL      C GDSG  L+C  +G     AG+VS G G      P V++RV+  +EWI  + S
Sbjct:  591 CDCGTRPYKHNRIVGGQNADVGEWPWQVSLH-----FKTQGHACGASIISNK----WLLCAAHCFIQPD--PSYKMTSS--WITYSGLRDQNTHDKSVQMRD-------------------------------LKTIITHPNY------ND---LTNDYDISLLELSQPLNFSNT--VHPICLP---ATSHVFTAGSSCFVTGWGTLREGGSAAQILQKAEVKVINDTVCNMVTEGQVTSRM-------MCSGYLSGGVDACQGDSGGPLVCLSEGGKWFQAGIVSWGEGCARRNKPGVYTRVTKLREWIREITS 840          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: TMPRSS9 (transmembrane serine protease 9 [Source:NCBI gene;Acc:100489279])

HSP 1 Score: 102.064 bits (253), Expect = 2.321e-22
Identity = 92/317 (29.02%), Postives = 135/317 (42.59%), Query Frame = 2
Query:   95 CVTCTHSSMEK--RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDY-QGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            C   T  +M+K  RI+GG +A   ++ W VS++ N +       CGA+++       WLV+AAHCF         +      W A +  T                             L G D    +T    I  II HP Y P            D D+A+++L  PL  ++ +    + LP+      +P +G  CI+ GWG  K  N   P + + A + I   S C +     LY N  ++   CAGYL+ K   C GDSG  L+C+   G   +AG+VS G G      P V+ RVS  + WI  +IS +
Sbjct:  224 CNCGTRPAMQKTNRIVGGSDATKGEFPWQVSLRENNEHF-----CGATVIGDK----WLVSAAHCFN--------DFQDPAVWVAYIATTS----------------------------LSGTDS---STVKATIRNIIKHPSYDPDTA---------DYDVAVLELDSPLKFNKYT--QPVCLPD--PTHVFP-VGKKCIITGWGYLKEDNLVKPEVLQKATVAIMDQSLCNS-----LYSNVVTERMLCAGYLEGKIDSCQGDSGGPLVCEEPSGKFFLAGIVSWGVGCAEARRPGVYVRVSKIRNWILDIISSS 473          

HSP 2 Score: 81.6481 bits (200), Expect = 8.025e-16
Identity = 83/301 (27.57%), Postives = 126/301 (41.86%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDYQ-GTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVIS 1021
            +I+GG +A   +  W  S+K           CGA+I+       WLV+AAHCF         N TK     A +G T                             L G D   +    + + ++I HP + P           +D D+A+++L   L  ++   V  + LP  S    +PA G  C++ GWG  K  N    ++K  +L+  S    +  + S LY    ++   CAG+L  K   C GDSG  L C+   G   +AG+VS G G      P V+SRV+  K+WI   ++
Sbjct:  530 KIVGGLDAVRGEIPWQASLKEGSRHF-----CGATIIGD----RWLVSAAHCF---------NQTKVDQVTAHMGSTA----------------------------LSGADTIAI---KISLKRVIQHPHFNP---------LTLDFDVAVLELASSLTFNKY--VQPVCLP--SALQKFPA-GWKCMISGWGNIKEGN----VSKPEVLQKASVGIIDQKICSVLYNFSITERMICAGFLDGKVDSCQGDSGGPLACEESPGIFFLAGIVSWGIGCAQAKKPGVYSRVTKLKDWILDTVA 763          

HSP 3 Score: 81.6481 bits (200), Expect = 8.926e-16
Identity = 83/326 (25.46%), Postives = 142/326 (43.56%), Query Frame = 2
Query:   38 SEFTKMKNTIYQFLIAFIFCVTCTHSSME--KRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLIC-DYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            S  + + + +  FL  + F + C  + +    +I+GG  +   ++ W VS+     + K    CGA ++       WL++AAHCF       +Y  +  K W A +G     FL    G  +K                              I +I  HP Y          ++ +DND+AL++L  PL    L  +  I LP+  ++  +P  G+ C + GWG TK   A +   + A + I  +  C+   P  + I+P    CAG+++     C GD+G  L C +  G   +AG+ S G+G     +P V++R+++ + WI
Sbjct:  829 SSPSTLSSFLTLFLYIYPFILDCGFAPVLPFNKIVGGSGSVRGEWPWQVSLWLRRKEHK----CGAVLISD----RWLLSAAHCF------DIY--SDPKLWAAYLG---TPFLNGVEGRVEK------------------------------IFRIHKHPFYN---------VYTLDNDVALLELPSPLTYTNL--IRPICLPD--ISHIFPE-GTRCFITGWGSTKEGGAMSRQLQKASVSIVGDQTCKKFYP--IQISPRM-LCAGFMQGGVDSCSGDAGGPLACREPSGRWFLAGITSWGYGCARPYFPGVYTRITSVRNWI 1088          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: TMPRSS9 (transmembrane serine protease 9 [Source:NCBI gene;Acc:100489279])

HSP 1 Score: 101.293 bits (251), Expect = 3.650e-22
Identity = 92/317 (29.02%), Postives = 135/317 (42.59%), Query Frame = 2
Query:   95 CVTCTHSSMEK--RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDY-QGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            C   T  +M+K  RI+GG +A   ++ W VS++ N +       CGA+++       WLV+AAHCF         +      W A +  T                             L G D    +T    I  II HP Y P            D D+A+++L  PL  ++ +    + LP+      +P +G  CI+ GWG  K  N   P + + A + I   S C +     LY N  ++   CAGYL+ K   C GDSG  L+C+   G   +AG+VS G G      P V+ RVS  + WI  +IS +
Sbjct:   37 CNCGTRPAMQKTNRIVGGSDATKGEFPWQVSLRENNEHF-----CGATVIGDK----WLVSAAHCFN--------DFQDPAVWVAYIATTS----------------------------LSGTDS---STVKATIRNIIKHPSYDPDTA---------DYDVAVLELDSPLKFNKYT--QPVCLPD--PTHVFP-VGKKCIITGWGYLKEDNLVKPEVLQKATVAIMDQSLCNS-----LYSNVVTERMLCAGYLEGKIDSCQGDSGGPLVCEEPSGKFFLAGIVSWGVGCAEARRPGVYVRVSKIRNWILDIISSS 286          

HSP 2 Score: 82.0333 bits (201), Expect = 6.632e-16
Identity = 85/331 (25.68%), Postives = 143/331 (43.20%), Query Frame = 2
Query:   35 FSEFTKMKNTIYQFLIAFI----FCVTCTHSSME--KRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLIC-DYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
             S+    ++T   FL  F+    F + C  + +    +I+GG  +   ++ W VS+     + K    CGA ++       WL++AAHCF       +Y  +  K W A +G     FL    G  +K                              I +I  HP Y          ++ +DND+AL++L  PL    L  +  I LP+  ++  +P  G+ C + GWG TK   A +   + A + I  +  C+   P  + I+P    CAG+++     C GD+G  L C +  G   +AG+ S G+G     +P V++R+++ + WI
Sbjct:  622 MSQTKSTRSTPSSFLTLFLYIYPFILDCGFAPVLPFNKIVGGSGSVRGEWPWQVSLWLRRKEHK----CGAVLISD----RWLLSAAHCF------DIY--SDPKLWAAYLG---TPFLNGVEGRVEK------------------------------IFRIHKHPFYN---------VYTLDNDVALLELPSPLTYTNL--IRPICLPD--ISHIFPE-GTRCFITGWGSTKEGGAMSRQLQKASVSIVGDQTCKKFYP--IQISPRM-LCAGFMQGGVDSCSGDAGGPLACREPSGRWFLAGITSWGYGCARPYFPGVYTRITSVRNWI 886          

HSP 3 Score: 81.2629 bits (199), Expect = 1.100e-15
Identity = 83/301 (27.57%), Postives = 126/301 (41.86%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASD--FCAGYLKKKYGLCHGDSGSGLICDYQ-GTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVIS 1021
            +I+GG +A   +  W  S+K           CGA+I+       WLV+AAHCF         N TK     A +G T                             L G D   +    + + ++I HP + P           +D D+A+++L   L  ++   V  + LP  S    +PA G  C++ GWG  K  N    ++K  +L+  S    +  + S LY    ++   CAG+L  K   C GDSG  L C+   G   +AG+VS G G      P V+SRV+  K+WI   ++
Sbjct:  343 KIVGGLDAVRGEIPWQASLKEGSRHF-----CGATIIGD----RWLVSAAHCF---------NQTKVDQVTAHMGSTA----------------------------LSGADTIAI---KISLKRVIQHPHFNP---------LTLDFDVAVLELASSLTFNKY--VQPVCLP--SALQKFPA-GWKCMISGWGNIKEGN----VSKPEVLQKASVGIIDQKICSVLYNFSITERMICAGFLDGKVDSCQGDSGGPLACEESPGIFFLAGIVSWGIGCAQAKKPGVYSRVTKLKDWILDTVA 576          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000011941.1 (trypsin-like [Source:NCBI gene;Acc:105945798])

HSP 1 Score: 94.7449 bits (234), Expect = 1.330e-21
Identity = 85/304 (27.96%), Postives = 127/304 (41.78%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWG--CTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +IIGG     +   + VS+            CG S++       W+V+AAHC+  S  V             R+G         +H +     E  +   N A                    K+I HP Y             +DNDI L+KL  P  ++  S V+T+ LP     SS  A G+ C+V GWG   T   N PN +  L    I + ++C  + P ++  N    FCAG+L+     C GDSG  ++C+ Q    + GVVS G+G     YP V+++V  +  WI   I+ N
Sbjct:   18 DDKIIGGSTCARNSVPYIVSLNSGYH------FCGGSLISNQ----WVVSAAHCYKASVQV-------------RLG---------EHNIA--LSEGTEQFINSA--------------------KVIRHPSYNSRT---------IDNDIMLIKLASPASLN--SNVNTVALP-----SSCAAAGTSCLVSGWGNLSTTTSNYPNLLQCLNA-PILTTAQCSGAYPGQITNNM---FCAGFLEGGKDSCQGDSGGPVVCNGQ----LQGVVSWGYGCAQRNYPGVYTKVCNYVSWIQNTIAAN 243          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000011928.1 (trypsin-like [Source:NCBI gene;Acc:105945798])

HSP 1 Score: 94.3597 bits (233), Expect = 1.625e-21
Identity = 85/304 (27.96%), Postives = 127/304 (41.78%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKV--KNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +IIGG     +   + VS+            CG S+L       W+V+AAHC+  S  V             R+G         +H +     E  +   N A                    K+I HP Y             +DNDI L+KL  P  ++  S V+T+ LP     SS  A G+ C++ GWG T     N PN +  L    I + ++C  + P ++  N    FCAG+L+     C GDSG  ++C+ Q    + GVVS G+G     YP V+++V  +  WI   I+ N
Sbjct:   11 DDKIIGGATCAKNSVPYIVSLNAGYHF------CGGSLLNNQ----WVVSAAHCYQASVQV-------------RLG---------EHNIA--VSEGTEQFINSA--------------------KVIRHPSYNSRT---------IDNDIMLIKLASPASLN--SAVNTVALP-----SSCAAAGTSCLISGWGNTSTTGSNYPNLLQCLN-APILTTAQCSGAYPGQITNNM---FCAGFLEGGKDSCQGDSGGPVVCNGQ----LQGVVSWGYGCAQRNYPGVYTKVCNYVSWIQNTIAAN 236          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000011936.1 (trypsin-like [Source:NCBI gene;Acc:105945798])

HSP 1 Score: 93.5893 bits (231), Expect = 3.904e-21
Identity = 84/304 (27.63%), Postives = 128/304 (42.11%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWG--CTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +IIGG     +   + VS+            CG S++       W+V+AAHC+  S  V             R+G         +H +     E  +   N A                    K+I HP Y             +DNDI L+KL  P  ++  S V+T+ LP     SS  A G+ C+V GWG   T   N P+ +  L    I + ++C ++ P ++  N    FCAG+L+     C GDSG  ++C+ Q    + GVVS G+G     YP V+++V  +  WI   I+ N
Sbjct:   18 DDKIIGGSTCARNSVPYIVSLNSGYH------FCGGSLISNQ----WVVSAAHCYKASVQV-------------RLG---------EHNIA--LSEGTEQFINSA--------------------KVIRHPSYNSRT---------IDNDIMLIKLASPASLN--SNVNTVALP-----SSCAAAGTSCLVSGWGNLSTTTSNYPDLLQCLNA-PILTTAQCSSAYPGQITNNM---FCAGFLEGGKDSCQGDSGGPVVCNGQ----LQGVVSWGYGCAQRNYPGVYTKVCNYVSWIQNTIAAN 243          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss3 (transmembrane protease, serine 3 [Source:MGI Symbol;Acc:MGI:2155445])

HSP 1 Score: 107.071 bits (266), Expect = 1.112e-24
Identity = 96/317 (30.28%), Postives = 134/317 (42.27%), Query Frame = 2
Query:   80 IAFIFCVTC-THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  + C  C T +    RI+GG  +   ++ W VS++     L     CG SI+ TP   LW+VTAAHC        VY+L   K W  +VGL  +                V S                       + KII H  Y+P          R+ NDIALMKL EPL   +   +  I LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYLK     C GDSG  L+C  +    + G  S G G      P V++R+++F +WI   +  +
Sbjct:  199 VVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----CGGSII-TP---LWIVTAAHC--------VYDLYHPKSWTVQVGLVSL------------MDSPVPSHL---------------------VEKIIYHSKYKPK---------RLGNDIALMKLSEPLTFDET--IQPICLPNSEEN--FPD-GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 450          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss3 (transmembrane protease, serine 3 [Source:MGI Symbol;Acc:MGI:2155445])

HSP 1 Score: 107.071 bits (266), Expect = 1.112e-24
Identity = 96/317 (30.28%), Postives = 134/317 (42.27%), Query Frame = 2
Query:   80 IAFIFCVTC-THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  + C  C T +    RI+GG  +   ++ W VS++     L     CG SI+ TP   LW+VTAAHC        VY+L   K W  +VGL  +                V S                       + KII H  Y+P          R+ NDIALMKL EPL   +   +  I LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYLK     C GDSG  L+C  +    + G  S G G      P V++R+++F +WI   +  +
Sbjct:  199 VVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----CGGSII-TP---LWIVTAAHC--------VYDLYHPKSWTVQVGLVSL------------MDSPVPSHL---------------------VEKIIYHSKYKPK---------RLGNDIALMKLSEPLTFDET--IQPICLPNSEEN--FPD-GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 450          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss3 (transmembrane protease, serine 3 [Source:MGI Symbol;Acc:MGI:2155445])

HSP 1 Score: 107.071 bits (266), Expect = 1.125e-24
Identity = 96/312 (30.77%), Postives = 132/312 (42.31%), Query Frame = 2
Query:   95 CVTC-THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            C  C T +    RI+GG  +   ++ W VS++     L     CG SI+ TP   LW+VTAAHC        VY+L   K W  +VGL  +                V S                       + KII H  Y+P          R+ NDIALMKL EPL   +   +  I LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYLK     C GDSG  L+C  +    + G  S G G      P V++R+++F +WI   +  +
Sbjct:  202 CSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----CGGSII-TP---LWIVTAAHC--------VYDLYHPKSWTVQVGLVSL------------MDSPVPSHL---------------------VEKIIYHSKYKPK---------RLGNDIALMKLSEPLTFDET--IQPICLPNSEEN--FPD-GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 448          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss3 (transmembrane protease, serine 3 [Source:MGI Symbol;Acc:MGI:2155445])

HSP 1 Score: 107.071 bits (266), Expect = 1.231e-24
Identity = 96/317 (30.28%), Postives = 134/317 (42.27%), Query Frame = 2
Query:   80 IAFIFCVTC-THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  + C  C T +    RI+GG  +   ++ W VS++     L     CG SI+ TP   LW+VTAAHC        VY+L   K W  +VGL  +                V S                       + KII H  Y+P          R+ NDIALMKL EPL   +   +  I LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYLK     C GDSG  L+C  +    + G  S G G      P V++R+++F +WI   +  +
Sbjct:  221 VVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----CGGSII-TP---LWIVTAAHC--------VYDLYHPKSWTVQVGLVSL------------MDSPVPSHL---------------------VEKIIYHSKYKPK---------RLGNDIALMKLSEPLTFDET--IQPICLPNSEEN--FPD-GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 472          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss2 (transmembrane protease, serine 2 [Source:MGI Symbol;Acc:MGI:1354381])

HSP 1 Score: 101.293 bits (251), Expect = 1.054e-22
Identity = 86/319 (26.96%), Postives = 136/319 (42.63%), Query Frame = 2
Query:   77 LIAFIFCVTCTHSSMEK--RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            ++  + C+ C   S+++  RI+GG  A P  + W VS+      ++    CG SI+ TP    W+VTAAHC           L+  +YW A  G+ +   ++  +G + +                              + K+I HP Y    K         +NDIALMKL+ PL  + L  V  + LPN  +      +  +C + GWG T  K   + +   A++ +   S+C +       I PA   CAG+L+     C GDSG  L+    G   + G  S G G      P V+  V+ F +WI++ +  N
Sbjct:  234 MVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLH-----VQGVHVCGGSII-TPE---WIVTAAHCVEEP-------LSSPRYWTAFAGILRQSLMF--YGSRHQ------------------------------VEKVISHPNYDSKTK---------NNDIALMKLQTPLAFNDL--VKPVCLPNPGMMLD---LDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAM-ICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRAN 489          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8K1T0|TMPS3_MOUSE (Transmembrane protease serine 3 OS=Mus musculus OX=10090 GN=Tmprss3 PE=1 SV=2)

HSP 1 Score: 107.071 bits (266), Expect = 7.779e-24
Identity = 96/317 (30.28%), Postives = 134/317 (42.27%), Query Frame = 2
Query:   80 IAFIFCVTC-THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  + C  C T +    RI+GG  +   ++ W VS++     L     CG SI+ TP   LW+VTAAHC        VY+L   K W  +VGL  +                V S                       + KII H  Y+P          R+ NDIALMKL EPL   +   +  I LPN   N  +P  G  C   GWG T+     +P+   A + + SN  C +       I+P S  CAGYLK     C GDSG  L+C  +    + G  S G G      P V++R+++F +WI   +  +
Sbjct:  199 VVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHL-----CGGSII-TP---LWIVTAAHC--------VYDLYHPKSWTVQVGLVSL------------MDSPVPSHL---------------------VEKIIYHSKYKPK---------RLGNDIALMKLSEPLTFDET--IQPICLPNSEEN--FPD-GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 450          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JIQ8|TMPS2_MOUSE (Transmembrane protease serine 2 OS=Mus musculus OX=10090 GN=Tmprss2 PE=2 SV=3)

HSP 1 Score: 101.293 bits (251), Expect = 7.369e-22
Identity = 86/319 (26.96%), Postives = 136/319 (42.63%), Query Frame = 2
Query:   77 LIAFIFCVTCTHSSMEK--RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            ++  + C+ C   S+++  RI+GG  A P  + W VS+      ++    CG SI+ TP    W+VTAAHC           L+  +YW A  G+ +   ++  +G + +                              + K+I HP Y    K         +NDIALMKL+ PL  + L  V  + LPN  +      +  +C + GWG T  K   + +   A++ +   S+C +       I PA   CAG+L+     C GDSG  L+    G   + G  S G G      P V+  V+ F +WI++ +  N
Sbjct:  234 MVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLH-----VQGVHVCGGSII-TPE---WIVTAAHCVEEP-------LSSPRYWTAFAGILRQSLMF--YGSRHQ------------------------------VEKVISHPNYDSKTK---------NNDIALMKLQTPLAFNDL--VKPVCLPNPGMMLD---LDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAM-ICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRAN 489          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q2KJ63|KLKB1_BOVIN (Plasma kallikrein OS=Bos taurus OX=9913 GN=KLKB1 PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 3.638e-21
Identity = 84/305 (27.54%), Postives = 132/305 (43.28%), Query Frame = 2
Query:  113 SSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            ++   RI+GG  A   ++ W VS++  V +   S  CG SI+       W++TAAHCF   DG+ + N+     W                               + Y  +    +    T    I +II+HP Y+ +  S+D         IAL+KL+ PL    L     I LP  S + + P + +DC + GWG T+ K       + A + + SN EC+ S   + Y       CAGY +     C GDSG  L+C ++ T  + G+ S G G      P V+++V+ + +WI     D+
Sbjct:  386 TTKRTRIVGGTNASWGEWPWQVSLQ--VKQRAQSHLCGGSIIGRQ----WVLTAAHCF---DGLLLSNI-----W-------------------------------RIYGGILNLSEITTETSFSQIKEIIVHPNYKISEGSHD---------IALIKLEAPLNFTDLQ--KAICLP--SKDDTKP-VYTDCWITGWGFTEEKGKIQNTLQKANIPLISNEECQKSY--RDYKITKQMICAGYKEGGKDACKGDSGGPLVCQHEETWHLVGITSWGEGCARREQPGVYTKVAEYVDWILEKTQDS 629          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|O15393|TMPS2_HUMAN (Transmembrane protease serine 2 OS=Homo sapiens OX=9606 GN=TMPRSS2 PE=1 SV=3)

HSP 1 Score: 98.9821 bits (245), Expect = 4.709e-21
Identity = 86/314 (27.39%), Postives = 127/314 (40.45%), Query Frame = 2
Query:   80 IAFIFCVTC---THSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            +  + C+ C    +SS + RI+GGE A P  + W VS+      ++    CG SI+ TP    W+VTAAHC           L    +W A  G+ +  F++   G +                                + K+I HP Y    K         +NDIALMKL++PL  + L  V  + LPN  +      +   C + GWG T+ K   + +   A + +     C +       I PA   CAG+L+     C GDSG  L+        + G  S G G      P V+  V  F +WI+R
Sbjct:  236 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLH-----VQNVHVCGGSII-TPE---WIVTAAHCVEKP-------LNNPWHWTAFAGILRQSFMFYGAGYQ--------------------------------VEKVISHPNYDSKTK---------NNDIALMKLQKPLTFNDL--VKPVCLPNPGMMLQPEQL---CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM-ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYR 486          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P57727|TMPS3_HUMAN (Transmembrane protease serine 3 OS=Homo sapiens OX=9606 GN=TMPRSS3 PE=1 SV=2)

HSP 1 Score: 98.5969 bits (244), Expect = 5.529e-21
Identity = 93/311 (29.90%), Postives = 132/311 (42.44%), Query Frame = 2
Query:   80 IAFIFCVTCTHSS-MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKV-KNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +  + C  C H      RI+GG  +   ++ W  S++     L     CG S++ TP   LW++TAAHC        VY+L   K W  +VGL                   V  L N A   L              + KI+ H  Y+P          R+ NDIALMKL  PL  +++  +  + LPN   N  +P  G  C   GWG T+      +P+   A + + SN  C +       I+P S  CAGYL      C GDSG  L+C  +    + G  S G G      P V++RV++F +WI
Sbjct:  199 VVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHL-----CGGSVI-TP---LWIITAAHC--------VYDLYLPKSWTIQVGL-------------------VSLLDNPAPSHL--------------VEKIVYHSKYKPK---------RLGNDIALMKLAGPLTFNEM--IQPVCLPNSEEN--FPD-GKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISP-SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A0X3NYH2 (Mast cell tryptase (Fragment) OS=Schistocephalus solidus OX=70667 GN=TRYT PE=3 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 6.327e-50
Identity = 99/310 (31.94%), Postives = 162/310 (52.26%), Query Frame = 2
Query:  125 KRIIGGEEAPPDKYRWAVSIKGNVDK----LKMSGA---CGASILQTPGQVLWLVTAAHCFYP-SDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVN-SSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +RII G+ A   +Y + VSI+  +      L   G    CG +++       W++TAAHC Y  ++   +  L   K WH R+   K         ++    ++++ LF++AY K+FG  K +      H+ KI+IHP Y             ++NDIAL+KLKEP+ +H++  +  + +PN + N ++WPA+G +C  +GWGC+     P    ++  L I +   C     + + +    +FCAG+ +   G+C GDSG  L+C++ G   +AG+VS  H   P  YPAVF+RVS F +W+  VI  +
Sbjct:   51 RRIISGQNAKNSEYPFIVSIQAKLQNGLHTLLFGGLEHFCGGTLIDP----RWILTAAHCMYAYTEEGELIRLLDVKQWHVRMATDK---------LRPSIMDRLRGLFHRAYNKIFGYRKLQTF---YHLKKIVIHPDYVEGF---------LENDIALLKLKEPILVHRIPTLDVLPMPNGTENYANWPAVGQNCTALGWGCSCATCPPEMYMQVLRLPIIAPQVCRKMYKAPINLTETKEFCAGFFRANTGICPGDSGGPLVCEHNGQKLLAGIVSATHAKKPESYPAVFTRVSYFVDWVRSVIEKD 335          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A4S2MLJ2 (Peptidase S1 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000382 PE=3 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.565e-48
Identity = 110/317 (34.70%), Postives = 162/317 (51.10%), Query Frame = 2
Query:  119 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKV---------DFLYQKHGMKDKFKEKVKSLFNKAYRK-LFGKDKFKVTTDD----LHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            ++KRII G +A    + WAVSIKG   +      CGA+I+       WL+TAAHCF+ +D      L  G YWHA+ G TK+         + +    G+ +     +++LF    +  LF     +  TDD    +H  KII+HP Y P     DD    ++ DIAL+KL+ PLPI   + ++   LP       WP +G+ C  VGWGC + +  P+   ++  L++ S+  C     +   +N   +FCAGY K   G+C GDSG GLI  ++    + GV S  H   P  YP +F+RVSAF +WI + +  N
Sbjct:   21 VDKRIINGYDAKGGDHPWAVSIKGIHPRTLSITYCGATIIADQ----WLLTAAHCFW-TDARRRSMLIPG-YWHAQAGHTKIVLGEEHTDREIIVGSSGIDEVGSNFLQNLFENLKKLILFKTPSDQAITDDKLWHIHFEKIILHPKYLP-----DD----LEYDIALVKLRAPLPIDGKT-LTAAKLPAGLTTGDWPPVGTQCTFVGWGCQRYQGEPSADLQVVALRVVSHDACTEMYNNGAGLNEHHEFCAGYYKSNVGICAGDSGGGLIQVFERQVVVVGVASATHAKQPQSYPGLFTRVSAFTDWIEKTVDSN 321          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A074Z675 (Peptidase S1 domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_15173 PE=3 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 1.818e-47
Identity = 110/318 (34.59%), Postives = 156/318 (49.06%), Query Frame = 2
Query:  119 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKF------KEKVKSLFNKAYRKLFGKDKFKVTTDD---------LHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            ++KRII G +A    + WAVSIKG          CGA+I+       WL+TAAHCF+ +D      L  G YWHA+ G TK+  L ++H  ++         E   +     +  L     FK +TD+         +H  KII+HP Y P    ND     ++ DIAL+KL+  LPI     ++   LP       WP +G+ C  VGWGC K +  P    ++  L++ S+  C         +N   +FCAGY +   G+C GDSG GLI  Y+    + GV S  H   P  YP +F+RVSAF +WI + +  N
Sbjct:   21 VDKRIINGYDAKTGDHPWAVSIKGIHPTTLSITYCGATIIAEQ----WLLTAAHCFW-TDARRKSMLNPG-YWHAQAGHTKI-VLGEEHTKREIIVGASDTDETGSNFLQNLFESLKKLILFKTSTDEAVADDKLWHVHFQKIILHPKYAP----ND-----LEYDIALVKLRAALPIDG-KKLAAAKLPAGLTTGDWPPVGTQCTFVGWGCQKYQGEPTANLQVVALRVVSHDACTEMYNHGAGLNEHHEFCAGYYQSNVGICAGDSGGGLIQMYERQVVVVGVASATHARQPQSYPGLFTRVSAFTDWIEKTVDSN 321          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A068YHF5 (Subfamily S1A unassigned peptidase S01 family OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001046200 PE=3 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 4.331e-47
Identity = 102/307 (33.22%), Postives = 157/307 (51.14%), Query Frame = 2
Query:  125 KRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVL---WLVTAAHCF--YPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPN-WSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +RII GE A  D++ + VSI+  +     S   G       G ++   W++TAAHC   Y  DG  V +L   K WH R+   K         ++    +++K  F++A+  LFG   ++      H++KII+HP Y             ++NDIAL+KLKE + +H++  +  + LPN   V   WP  G +C  VGWG T +   P    ++  + I   ++C +     + +  +S+FCAGY KK  G+C GDSG  L+C+++G   +AGV S  H   P  YPAVF+RV  F +WI   +  N
Sbjct:   37 RRIINGELAEMDEFPFIVSIQAKLSNDIYSRIFGGVEHFCGGTLISPRWILTAAHCMFAYTDDGKQV-SLLNPKAWHVRMATDK---------LRPSVIDRMKGFFHRAFNTLFG---YRKPQTFYHLAKIILHPDYVEGF---------LENDIALLKLKEHVLVHRMKSLDLLALPNPHIVGKIWPKTGQNCSAVGWGSTCINCPPEMYMRVVNMPIIDPNKCRSMYKVSINLTESSEFCAGYFKKNVGVCSGDSGGPLVCEFEGERLLAGVTSAIHAKTPQSYPAVFTRVVRFADWISETMKKN 321          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A5K3F8T1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 1.262e-46
Identity = 102/311 (32.80%), Postives = 158/311 (50.80%), Query Frame = 2
Query:  125 KRIIGGEEAPPDKYRWAVSIKG----NVDKLKMSGA---CGASILQTPGQVLWLVTAAHCFYP--SDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWS-VNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +RII GE A  ++Y + VSI+     ++  L   G    CG +++       W++TAAHC Y    DG  +  LT  K WH R+   K         +K    +++K  F++A+  LFG  K +      HI K ++HP Y             ++NDIAL+KLKE + +H+++ +  I LP+   V   WP  G +C  +GWGC      P    K   + I    +C+    + + +  A +FC+G+  +  G+C GDSG  L+CD+ G   +AGVVS  H   P  +PAVF+RV+ F++WI   I +N
Sbjct:   21 RRIINGELAKKNRYPFIVSIQAKLSNDLHSLLFGGIEHFCGGALVAP----RWILTAAHCMYAYSKDGELIPLLTP-KSWHVRMSTDK---------LKPSTIDRLKGFFHRAFNTLFGYIKPQTF---YHIEKFVLHPHYVEGY---------LENDIALLKLKEHVQVHRMNTLDVIKLPDPKLVGEMWPKTGQECTAIGWGCACAHCPPEMYMKTIKMPIIDPRKCKAMYKAPINLTVAKEFCSGFFNRNSGICPGDSGGPLVCDFNGNQLLAGVVSATHAKKPESFPAVFTRVTYFRDWILETIKNN 305          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000049166.1 (serine protease 56 [Source:NCBI gene;Acc:103021696])

HSP 1 Score: 100.523 bits (249), Expect = 3.149e-22
Identity = 87/304 (28.62%), Postives = 131/304 (43.09%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGA--CGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVG---LTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQ--GTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVI 1018
            RI+GG  APP  + W V+       L++ GA  CG  ++ +     W++TAAHCF  S            YW A VG   +TK D            +E+V                       L ++++I HP + P            +NDIAL++L  P+ +     V+ + LP+       P  G+ C+V GWG          +   A + + S   C++++  +L  N  + FCAGYL      C GDSG  LI   +  G   + G+ S G G    G P V++RV+AF +WI   I
Sbjct:   97 RIVGGSPAPPGSWPWLVN-------LQLDGALMCGGVLVDSS----WVLTAAHCFAGSRS--------DSYWTAVVGEFDITKTDP-----------EEQV-----------------------LKVNRVITHPKFNPKT---------FNNDIALVELTSPVVLS--DQVTPVCLPS----GIEPPTGTPCLVAGWGSLYEDGPAADVVMEAKVPLLSQGTCKSALGKELLTN--TMFCAGYLSGGIDSCQGDSGGPLIFQDRITGRFQLYGITSWGDGCGEKGKPGVYTRVTAFTDWILSEI 330          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: tmprss9 (transmembrane serine protease 9 [Source:ZFIN;Acc:ZDB-GENE-050208-573])

HSP 1 Score: 99.3673 bits (246), Expect = 7.786e-22
Identity = 82/299 (27.42%), Postives = 135/299 (45.15%), Query Frame = 2
Query:  116 SMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICD-YQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIF 1009
            +M  R++GG+ A   ++ W VS+K     L+    CGASI+ +     W+V+AAHCF   +          K W A VG + V                             G +    T   ++I  +I+ P Y P            D+D+ +++L++PL       +  + +P++S ++  P  G +CIV GWG     +   P  + A++K+  +  C +SV  +  I   +  CAG+L+ +   C GDSG  L+C+   G   +AG+VS G G      P V+SRV+  + WI 
Sbjct:  222 AMGSRVVGGQNARHGEFPWQVSLK-----LRGRHTCGASIISS----RWIVSAAHCFENKNP---------KDWRALVGSSLVS----------------------------GAENGATT---INIKSLIVSPDYNP---------MTTDSDVTVLELEKPLTFSAY--IQPVCIPSFS-HTFIP--GQNCIVSGWGALSQDSEVPPTLQKAVVKVIDSDVCNSSVVYRGAIT-NNMMCAGFLQGRVDSCQGDSGGPLVCEGAPGRFFLAGIVSWGVGCAQVNKPGVYSRVTKLRNWIM 456          

HSP 2 Score: 84.3445 bits (207), Expect = 5.407e-17
Identity = 80/299 (26.76%), Postives = 122/299 (40.80%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWS---VNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDY-QGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
             +RI+GG  A   ++ W  S++      + S  CGA+++       W++TAAHCF P+             W   +G                 +  V +L                    + + + IIHP +  +          MD D+AL++L  P P      + T+ LP+ S    NSS      +C ++GWG  +       + K A + I   S+C  S   +L  N     CAG ++     C GDSG  L C    G   +AGV S GHG     +P V+ RV+A +EWI
Sbjct:  467 RQRIVGGVTARRGEWPWVASLQ-----FQRSHRCGATLIHCK----WILTAAHCFEPNP----------SGWTVSLG--------------SVLRSGVSALV-------------------IPVQRFIIHPNFTSST---------MDFDVALVELSIPAPSSYT--IQTLCLPSPSHSFFNSS------ECYIMGWGAIREDKLTTLLQK-AKVSIIDQSDCLPSYSGRLTANMV---CAGSMEGGKDTCLGDSGGPLACRQPHGRWFLAGVTSWGHGCGRSSFPGVYMRVTAVREWI 692          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: tmprss5 (transmembrane serine protease 5 [Source:ZFIN;Acc:ZDB-GENE-131121-184])

HSP 1 Score: 95.9005 bits (237), Expect = 8.747e-22
Identity = 91/328 (27.74%), Postives = 133/328 (40.55%), Query Frame = 2
Query:   47 TKMKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDF--LYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVIS 1021
            ++  +  Y   + F+ C  C   +   RI+GG EA P ++ W VS+            CG SI+ +     W+VTAAHC        VY L +   W    G+   +   L Q  G   +     K ++NK Y                H S                      DNDIALMKL+ PL       +    LP +  +   P  G+ C + GWG T+  +   P   K A + + S  +C +S      I  +   CAGY + K   C GDSG  L+C       + GVVS G G     +P V+++V+ F  WI+ +I 
Sbjct:    3 SRQNSLSYIECVIFLSCAECGTRAKLPRIVGGVEATPGRWPWQVSLY-----YSNRHTCGGSIITSQ----WIVTAAHC--------VYRLPQVSSWVVYAGIVTRNTAKLAQYTGYAVE-----KIIYNKNYN---------------HRSH---------------------DNDIALMKLRTPLNFSDT--IRPACLPQY--DHDLPG-GTQCWISGWGYTQPDDVHIPDTLKEAPVPLISTKKCNSSCMYNGEIT-SRMLCAGYTEGKVDACQGDSGGPLVCQDDNVWRLVGVVSWGTGCAEPNHPGVYTKVAEFLGWIYEMIE 266          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000017181.2 (trypsin-3-like [Source:NCBI gene;Acc:103044944])

HSP 1 Score: 94.3597 bits (233), Expect = 1.207e-21
Identity = 83/304 (27.30%), Postives = 133/304 (43.75%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCT--KVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +I+GG E P +   + VS+            CG S++ T     W+++AAHC+  S             +  R+G         +H +K   +               G ++F      +  +KII HP Y              +NDI L+KLK P  ++  S VST+ LP     SS  + G+ C++ GWG T     N P+ +  L    I S+S C  + P  +  N    FCAG+++     C GDSG  ++C+ +    + G+VS G+G      P V+++V  +  WI R I +N
Sbjct:   20 DDKIVGGYECPKNSVPYQVSLNIGYHY------CGGSLITTE----WVLSAAHCYKSS-------------YQVRLG---------EHNIKSDDE---------------GTEQF------IDSAKIIKHPSYSS---------LTFNNDIMLIKLKSPATLN--SYVSTVALP-----SSCASAGTSCLISGWGNTLSSGSNYPDTLQCLDA-PILSDSNCRRAYPLLITSNM---FCAGFMEGGKDSCQGDSGGPVVCNGE----VQGIVSWGYGCAQKNSPGVYTKVCNYNSWINRTIQNN 246          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000030599.1 (trypsin-2-like [Source:NCBI gene;Acc:103029195])

HSP 1 Score: 93.9745 bits (232), Expect = 1.714e-21
Identity = 78/302 (25.83%), Postives = 126/302 (41.72%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +I+GG E  P    W VS+            CG S++       W+V+AAHC+                       ++++    +H ++                        + T  ++  SK+I HP Y           + +DNDI L+KL  P  ++  S V  + LP      S  A G+ C V GWG T    A     +   + I ++ +C+NS P  +     S FCAGYL+     C GDSG  ++C+ +    + GVVS G+G     +P V+++V  F  W+ + +S N
Sbjct:   18 DDKIVGGYECTPYSQPWQVSLNAGYH------FCGGSLVNEN----WVVSAAHCYK----------------------SRIEVRLGEHNIQ----------------------VTEGTEQNIPSSKVIRHPSYDS---------WTIDNDIMLIKLSTPARLN--SNVQPVALPK-----SCAAAGTRCTVSGWGNTMSSTADRNKLQCLEIPIIADKDCDNSYPGMI---TDSMFCAGYLEGGKDSCQGDSGGPVVCNGE----LQGVVSWGYGCAEKDHPGVYAKVCKFSSWLQQTMSSN 242          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007992.1 (pep scaffold:Pmarinus_7.0:GL479522:6599:9454:1 gene:ENSPMAG00000007230.1 transcript:ENSPMAT00000007992.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.5077 bits (223), Expect = 4.299e-21
Identity = 78/302 (25.83%), Postives = 122/302 (40.40%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            E  I+GG E       W VS+            CG S++ +     W+V+AAHC+  +  ++V           R+G         +H +            N+             T   +  SK I HP Y           + +DNDI L+KL  P  ++Q +    I LP+  VN+     G  C + GWG T+       +       + S++ C NS P  +  N     C GYL+     C GDSG  ++C+ +    + G+VS G G     YP V+++V  +  WI + I+ N
Sbjct:    8 EDHIVGGSECAAHSQPWQVSLNIGYH------FCGGSLINSQ----WVVSAAHCYQTASRISV-----------RIG---------EHNI----------FVNEG------------TEQQIQASKAIQHPQYNS---------WTIDNDIMLIKLSSPATLNQYA--QAIALPSSCVNT-----GVMCTISGWGETQTSVGSPDVLMCVQAPVLSDTSCRNSYPGDITNNM---ICLGYLEGGKDSCQGDSGGPVVCNGE----LQGIVSWGRGCALPNYPGVYTKVCNYNAWIAQTIAAN 234          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004281.1 (pep scaffold:Pmarinus_7.0:GL479205:9482:14995:-1 gene:ENSPMAG00000003912.1 transcript:ENSPMAT00000004281.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 7.274e-21
Identity = 77/302 (25.50%), Postives = 120/302 (39.74%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            E  I+GG E       W VS+            CG S++ +     W+V+AAHC+  +  ++V           R+G   +                     N+             T   +  SK I HP Y           + +DNDI L+KL  P  ++Q +    I LP+  VN+     G  C + GWG T+       +       + S++ C NS P  +  N     C GYL+     C GDSG  ++C+ +    + G+VS G G     YP V+++V  +  WI + I+ N
Sbjct:   21 EDHIVGGSECAAHSQPWQVSLNIGYH------FCGGSLINSQ----WVVSAAHCYQTASRISV-----------RIGEHNI-------------------FVNEG------------TEQQIQASKAIQHPQYNS---------WTIDNDIMLIKLSSPATLNQYA--QAIALPSSCVNT-----GVMCTISGWGETQTSVGSPDVLMCVQAPVLSDTSCRNSYPGDITNNM---ICLGYLEGGKDSCQGDSGGPVVCNGE----LQGIVSWGRGCALPNYPGVYTKVCNYNAWIAQTIAAN 247          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010026.1 (pep scaffold:Pmarinus_7.0:GL476399:2596494:2601138:1 gene:ENSPMAG00000009070.1 transcript:ENSPMAT00000010026.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 7.274e-21
Identity = 77/302 (25.50%), Postives = 120/302 (39.74%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            E  I+GG E       W VS+            CG S++ +     W+V+AAHC+  +  ++V           R+G   +                     N+             T   +  SK I HP Y           + +DNDI L+KL  P  ++Q +    I LP+  VN+     G  C + GWG T+       +       + S++ C NS P  +  N     C GYL+     C GDSG  ++C+ +    + G+VS G G     YP V+++V  +  WI + I+ N
Sbjct:   21 EDHIVGGSECAAHSQPWQVSLNIGYH------FCGGSLINSQ----WVVSAAHCYQTASRISV-----------RIGEHNI-------------------FVNEG------------TEQQIQASKAIQHPQYNS---------WTIDNDIMLIKLSSPATLNQYA--QAIALPSSCVNT-----GVMCTISGWGETQTSVGSPDVLMCVQAPVLSDTSCRNSYPGDITNNM---ICLGYLEGGKDSCQGDSGGPVVCNGE----LQGIVSWGRGCALPNYPGVYTKVCNYNAWIAQTIAAN 247          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmprss3a (transmembrane serine protease 3a [Source:ZFIN;Acc:ZDB-GENE-070912-70])

HSP 1 Score: 90.5077 bits (223), Expect = 4.288e-20
Identity = 84/314 (26.75%), Postives = 130/314 (41.40%), Query Frame = 2
Query:   80 IAFIFCVTCTHS-SMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVT--TDDL--HISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            +  I C+ C  S     RI+GG++A    + W VS++ N         CG ++L TP    W+++AAHC                                                   ++   G D + VT  T +L   ISKII +  Y   V + ++     D DIAL+KL +PL +    G +   LPN+  +     +G +C + GWG TKV   P       ++    ++E  N+  S      +   CAG+++     C GDSG  L+C    T  + G  S G G     +P V+SRV+A+ +WI
Sbjct:  105 VVSISCLACGSSIKSTSRIVGGQDAQLGSWPWQVSLQFNGQH-----TCGGTLL-TP---TWVLSAAHC---------------------------------------------------FQGYLGPDMWNVTDLTSNLAGSISKIITNSQY---VDNTNN-----DYDIALVKLSKPLSMSNTIGPAC--LPNYQTDFQ---VGMNCWITGWGATKVSAGPASTTLQEVMVPILSTETCNAANSYNGQITSRMVCAGFMQGGQDACQGDSGGPLVCQTGTTWFVVGATSFGEGCALTNFPGVYSRVTAYLDWI 345          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004829.1 (pep scaffold:Pmarinus_7.0:GL487651:3325:6603:-1 gene:ENSPMAG00000004392.1 transcript:ENSPMAT00000004829.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.6557 bits (213), Expect = 1.118e-19
Identity = 77/302 (25.50%), Postives = 118/302 (39.07%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            E  I+GG E       W VS+            CG S++ +     W+V+AAHC+  +  ++V           R+G   +   +   G + + +                             SK I HP Y  A          +DNDI L+KL  P  ++Q +    I LP     SS    G  C + GWG T+       +       + S++ C NS P  +  N     C GYL+     C GDSG  ++C+ Q    + G+VS G G     YP V+++V  +  WI   ++ N
Sbjct:   19 EDHIVGGYECAAHSQPWQVSLNIGYH------FCGGSLISSE----WVVSAAHCYQTASRISV-----------RIGEHNI---FVTEGTEQRIQA----------------------------SKAIRHPQYNSAT---------IDNDIMLIKLSSPATLNQYA--QAIPLP-----SSCVGTGVMCTISGWGETQTSVGSPDVLMCVQAPVLSDTSCRNSYPGDITNNM---ICLGYLEGGKDSCQGDSGGPVVCNGQ----LQGIVSWGRGCALPNYPGVYTKVCNYNSWIASTMAAN 245          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO31586 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXH0])

HSP 1 Score: 99.7525 bits (247), Expect = 7.239e-24
Identity = 88/310 (28.39%), Postives = 131/310 (42.26%), Query Frame = 2
Query:  119 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHC-----FYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGL-----CHGDSGSGLICDYQGTPTIAGVVSRGHGSDP----GGYPAVFSRVSAFKEWI 1006
            +EKR++ G E  P  + W V +  + D   +   CG +++       W+VTAAHC      Y S  V V N               +D+L+         KE  +              +F V+T  LH  + +   GY                DIAL+KL  P  I++   V T+ LP      S    G+ C + GWG T +    +   + A L I    EC NS      ++  S  CAGY + +  L     C+GDSG   +CD  G+  + GVVS G   DP    G + +VF+R+S+F +W+
Sbjct:    1 LEKRVVSGSEVEPQSWPWQVHLLQSRDGSFLH-KCGGALIDRE----WVVTAAHCCAFKVHYLSTDVVVDNF--------------LDWLFFTGDFNRDIKEPTEQ-------------EFDVSTLHLH-QRFLTDKGY--------------GYDIALLKLSRPAVINEF--VRTVCLP---AQGSRALEGTMCFITGWGKTNITEDKSVTLREAQLPIVGQKECNNSNSWFHIVDETSMLCAGYGENRGNLSKISGCNGDSGGPFVCDEGGSWVLRGVVSWG---DPKCQAGSFYSVFTRISSFIDWM 255          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO44208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW61])

HSP 1 Score: 96.6709 bits (239), Expect = 5.838e-23
Identity = 85/300 (28.33%), Postives = 127/300 (42.33%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSG--ACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKY-GLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRV 1015
            RII G+ A P  + W +S++G       SG   CG S++       W+VTAAHC + +     Y +  G   H + G T V                                        L +S+II HP Y      ND    R+ NDIAL++L  P+       V T+ L +       PA G  C + GWG        +P I + A+L I S+  C         ++  +  CAG  +    G C+GDSG  L+C+  G+  + G VS G  + P  +  VF+RV+++ +WI R+
Sbjct:    2 RIINGQNAQPHSWPWQISLRGR------SGFHTCGGSLISD----RWVVTAAHCIHRNKNPGGYTVVVGA--HKKRGSTSVQ-------------------------------------QSLRLSQIIEHPKY------NDR---RIVNDIALIELATPVQFDSAGKVGTVCLTDQR-----PAPGKRCYITGWGAINGDTQQSPDILQQAMLPIASHENCRRKYGD---VSSTAHLCAGEARSDAAGGCNGDSGGPLVCEDNGSWFLHGAVSYGLRNCPTTHYTVFARVASYTDWIKRM 235          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO30506 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0K9])

HSP 1 Score: 92.8189 bits (229), Expect = 1.781e-21
Identity = 78/300 (26.00%), Postives = 128/300 (42.67%), Query Frame = 2
Query:  119 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNP-IAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLK-KKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFR 1012
            M  RI+GG +A P  + W VS++      ++   CG +++       W+VTA HC   +   + Y +  G                                   A+R+L      +V    + + +I  H G+          M+R  +DIAL++L+ P  ++    V+ +  P        P +GS C + GWG     + P P I + A + I S+ +C+    S +Y    +  CAG  K    G C GDSG  L+C+  G  T+ GVVS G G+       V+++VS + +WI +
Sbjct:    1 MWTRIVGGHDAAPHSWPWQVSLRE-----ELGHTCGGTLIAPE----WVVTATHCIIMNPSPSSYTVALG-----------------------------------AHRRLSSNTAEQV----IKVKRIFKHSGFS---------MWRYRDDIALLQLERPAQLNDRVNVACLPSPG-----DVPPVGSKCWLTGWGRQVDSSGPLPDILQQARIPIASHEDCKRKYGSGIY--SYTHLCAGEAKPNAAGACQGDSGGPLVCERNGQWTLYGVVSFGAGNCEVTSYTVYTKVSNYLDWITK 236          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO34807 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNB8])

HSP 1 Score: 91.2781 bits (225), Expect = 3.747e-21
Identity = 77/293 (26.28%), Postives = 120/293 (40.96%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWI 1006
            R+IGG++A P  + W +++K   + +     CG S++ +     W+VTAAHC   S     Y +  G++                                        ++  +VT + L++ K+I HP Y            R+ NDIAL++L  P  +   S V+ + LP        PA GS C + GWG  K   + +PI + A++   S ++C+            S  CAG        C GDSG  L+C+  G   I G  S GHG    G   V++ V     W+
Sbjct:    2 RVIGGKDAIPGAWPWQIALKSRGNFI-----CGGSLVSS----TWVVTAAHCVARSSNPAQYQIIVGEH---------------------------------------NRNVNEVTEETLNVKKVIAHPQYNNP---------RLSNDIALIELASPAKLS--SRVNPVCLPPHGYK--LPA-GSRCFITGWGKIKHPGSSHPILQQAMIPSLSEAQCKQKAQQS---GCNSMLCAGLYNGGIDACQGDSGGPLVCETGGQFYIHGATSWGHGCAAPGKYGVYAHVKNLIGWV 229          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO34771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNF5])

HSP 1 Score: 91.6633 bits (226), Expect = 4.809e-21
Identity = 83/303 (27.39%), Postives = 132/303 (43.56%), Query Frame = 2
Query:  128 RIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCT-KVKNAPNPIAKLAILKIWSNSECENSVPSKLY-INPASDFCAGYLKK-KYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            R+I G+ A P  + W +S++          +CG +++       W+VTA+HC + +   + Y +  G   H R G T V                                      + + +S +I HP Y       DD   ++ NDIAL++L  P+   +   V T  L N       P  G  C + GWG T    N+P  I + A+L I S+++C+N    K Y ++  +  CAG  +    G C+GDSG  L+C+  G   + G VS G    P  Y  VF+RV+++ +WI +V  + 
Sbjct:   16 RVINGQNAQPHSWPWQISLR----PYGRYHSCGGTLISD----RWVVTASHCVHKNPRPS-YTVVVGA--HERNGKTAVQ-------------------------------------ESIPVSHVIEHPEY-------DD--RKIKNDIALLELSRPVKFDREGKVGTACLTNQQ-----PTPGKRCYITGWGSTIGTGNSPR-ILQQAMLPIASHNDCKN----KYYGVSSTAHLCAGEARSGASGGCNGDSGGPLVCEDNGRWYLHGAVSYGKLHCPTTYYTVFARVASYTDWIKQVTGNQ 251          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000041614.1 (pep primary_assembly:ASM223467v1:8:2529637:2537084:1 gene:ENSORLG00000026241.1 transcript:ENSORLT00000041614.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.2857 bits (238), Expect = 6.193e-22
Identity = 89/327 (27.22%), Postives = 143/327 (43.73%), Query Frame = 2
Query:   53 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVK-NAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 1030
            ++NT  QF    +F   C  +++  RI+GG++AP   + W VS++G+         CG S++       W++TAAHCF PS   +              G+T V  L    G             N+  R                I+ +I+HP +  A +         +NDIAL++L  P+       ++ + LP  S  S++ + G +  V GWG  ++   AP  + ++ I  I  N  C+ S  + L  +  +  CAG L      C GDSG  L+         AG+VS G G     +P +++RVS ++ WI   I+ NK
Sbjct:    3 LENT-SQFCSVLLFFPVCGRANLNNRIVGGQDAPAGFWPWQVSLQGSRH------FCGGSLINNQ----WVLTAAHCF-PSRSAS--------------GVTVVLGLQSLQGSNP----------NRVSRT---------------ITTLIVHPNFNSATQ---------NNDIALLQLSSPVTFTNY--ITPVCLP--STGSTFYS-GVNTWVTGWGTIRISLPAPQTLQEVQI-PIVGNRRCKCSYGASLITD--NMMCAGLLAGGKDSCQGDSGGPLVIKQNIRWIQAGIVSFGKGCALPNFPGIYTRVSQYQTWINTQITTNK 261          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: tryp (trypsinogen [Source:NCBI gene;Acc:100125451])

HSP 1 Score: 94.7449 bits (234), Expect = 8.499e-22
Identity = 81/325 (24.92%), Postives = 135/325 (41.54%), Query Frame = 2
Query:   53 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            M++ ++  LI   F +       + +I+GG E  P      VS+            CG S++       W+V+AAHC+                       ++V+    +H +++                  G ++F  +      S++I HP Y           + +DNDI L+KL  P  ++Q   V  + LP     S     G+ C+V GWG T          +   + I S+S+C NS P  +     S FCAGYL+     C GDSG  ++C+ Q    + G+VS G+G     +P V+++V  F +W+   ++ N
Sbjct:    1 MRSLVFVLLIGAAFALD------DDKIVGGYECTPHSQPHQVSLNAGYH------FCGGSLVNQN----WVVSAAHCYQ----------------------SRVEVRLGEHHIRNND----------------GTEQFITS------SRVIRHPSYNS---------YTIDNDIMLIKLSTPATLNQY--VQPVSLP-----SGCAPAGTMCLVSGWGNTMSPADDGDKLQCLNIPILSDSDCSNSYPGMI---TNSMFCAGYLEGGKDSCQGDSGGPVVCNGQ----LQGIVSWGYGCAERNHPGVYAKVCIFSDWLDSTMASN 242          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027744.1 (trypsin-2 [Source:NCBI gene;Acc:101161921])

HSP 1 Score: 94.7449 bits (234), Expect = 8.499e-22
Identity = 81/325 (24.92%), Postives = 135/325 (41.54%), Query Frame = 2
Query:   53 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            M++ ++  LI   F +       + +I+GG E  P      VS+            CG S++       W+V+AAHC+                       ++V+    +H +++                  G ++F  +      S++I HP Y           + +DNDI L+KL  P  ++Q   V  + LP     S     G+ C+V GWG T          +   + I S+S+C NS P  +     S FCAGYL+     C GDSG  ++C+ Q    + G+VS G+G     +P V+++V  F +W+   ++ N
Sbjct:    1 MRSLVFVLLIGAAFALD------DDKIVGGYECTPHSQPHQVSLNAGYH------FCGGSLVNQN----WVVSAAHCYQ----------------------SRVEVRLGEHHIRNND----------------GTEQFITS------SRVIRHPSYNS---------YTIDNDIMLIKLSTPATLNQY--VQPVSLP-----SGCAPAGTMCLVSGWGNTMSPADDGDKLQCLNIPILSDSDCSNSYPGMI---TNSMFCAGYLEGGKDSCQGDSGGPVVCNGQ----LQGIVSWGYGCAERNHPGVYAKVCIFSDWLDSTMASN 242          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040914.1 (pep primary_assembly:ASM223467v1:8:2529365:2537213:1 gene:ENSORLG00000026241.1 transcript:ENSORLT00000040914.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 94.7449 bits (234), Expect = 1.543e-21
Identity = 86/317 (27.13%), Postives = 140/317 (44.16%), Query Frame = 2
Query:   83 AFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVK-NAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 1030
            + +F   C  +++  RI+GG++AP   + W VS++G+         CG S++       W++TAAHCF PS G TV  L  G                                     + L G +  +V+     I+ +I+HP +  A +         +NDIAL++L  P+       ++ + LP  S  S++ + G +  V GWG  ++   AP  + ++ I  I  N  C+ S  + L  +  +  CAG L      C GDSG  L+         AG+VS G G     +P +++RVS ++ WI   I+ NK
Sbjct:   16 SLLFFPVCGRANLNNRIVGGQDAPAGFWPWQVSLQGSRH------FCGGSLINNQ----WVLTAAHCF-PS-GPTVQMLVLG------------------------------------LQSLQGSNPNRVSRT---ITTLIVHPNFNSATQ---------NNDIALLQLSSPVTFTNY--ITPVCLP--STGSTFYS-GVNTWVTGWGTIRISLPAPQTLQEVQI-PIVGNRRCKCSYGASLITD--NMMCAGLLAGGKDSCQGDSGGPLVIKQNIRWIQAGIVSFGKGCALPNFPGIYTRVSQYQTWINTQITTNK 264          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: prss1 (trypsin-3 [Source:NCBI gene;Acc:101154931])

HSP 1 Score: 93.2041 bits (230), Expect = 2.919e-21
Identity = 79/303 (26.07%), Postives = 128/303 (42.24%), Query Frame = 2
Query:  122 EKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAI-LKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            + +I+GG E   +   + VS+            CG S++ +     W+V+AAHC+                  +R+ +   +     +   ++F + VK                           II HP Y           + +DNDI L+KL  P  ++  S VST+ LP     SS  A G+ C++ GWG T    +  P   + +   I S++ C NS P ++  N    FCAG+L+     C GDSG  ++C+ Q    + G+VS G+G      P V+++V  +  WI   +S N
Sbjct:   20 DDKIVGGYECRKNSVPYQVSLNVGYH------FCGGSLISS----TWVVSAAHCY-----------------QSRIQVRLGEHNIAVNEGTEQFIDSVK---------------------------IIRHPSYSS---------WNLDNDIMLIKLSTPASLN--SYVSTVSLP-----SSCAAAGTSCLISGWGNTSASGSNYPDRLMCLDAPILSDTNCRNSYPGEITSNM---FCAGFLEGGKDSCQGDSGGPVVCNNQ----LQGIVSWGYGCAQKNRPGVYTKVCNYNTWIRNTMSSN 245          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000040907.1 (SMESG000040907.1)

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 325/326 (99.69%), Postives = 326/326 (100.00%), Query Frame = 2
Query:   53 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 1030
            MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVN+SWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK
Sbjct:    1 MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNTSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 326          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000040907.1 (SMESG000040907.1)

HSP 1 Score: 626.706 bits (1615), Expect = 0.000e+0
Identity = 303/304 (99.67%), Postives = 304/304 (100.00%), Query Frame = 2
Query:  119 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 1030
            MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVN+SWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK
Sbjct:    1 MEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNTSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDNK 304          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000077268.1 (SMESG000077268.1)

HSP 1 Score: 374.4 bits (960), Expect = 2.660e-128
Identity = 178/319 (55.80%), Postives = 229/319 (71.79%), Query Frame = 2
Query:   71 QFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +FL + IF V+ +   ++KR+IGGE APPDKYRWAVSIKG+VD+LK SGACGASI++T G + WL+TAAHCF+PS+ +  ++LTK + WHARVGL KVDF Y+KHG       K+ S F+KA++KLFG  K  VTT D+HI KI IHP Y            R++NDIALMKL +PLPI QL GV+TI LP+    + WP +GSDC+VVGWGCTK    PN  AKLA+LK+W N +C ++  + + +NP S+FCAGYLK+KYGLC GDSGSGL C Y G   +AGVVS  H  +PG +PA+F++V +FK WI   I+ N
Sbjct:    5 EFLSSLIFVVSISTGQIDKRVIGGETAPPDKYRWAVSIKGDVDELKTSGACGASIIKTKGNISWLLTAAHCFFPSNKIKTFDLTKPELWHARVGLMKVDFYYKKHGRGYLSNNKLISFFSKAFKKLFGNSKNVVTTGDIHIKKIFIHPDYVST---------RLENDIALMKLIDPLPIEQLKGVNTIELPDIPNLTKWPPVGSDCVVVGWGCTKAAGVPNTYAKLALLKVWDNDKCIDAFVAPIDLNPESEFCAGYLKRKYGLCPGDSGSGLACKYDGRWMLAGVVSAAHSKEPGQFPAIFTKVPSFKNWILDTINKN 314          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000077235.1 (SMESG000077235.1)

HSP 1 Score: 250.751 bits (639), Expect = 2.344e-80
Identity = 126/305 (41.31%), Postives = 181/305 (59.34%), Query Frame = 2
Query:  113 SSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  +KRIIGG+    D+++W VSIKG++  ++ +    ASI+++   + WLVTAAHCF+PS+GVT  +++    WH  V LTK D +Y+KHG+KDK  EK+KS+            K K+ T+D H+ KII+HP Y+P  ++N +    +DNDIAL+KL +PLP +  S +  + LP  SV   WP     C+V GW C K+ N  N  +K   LKI SN +CE        +N  +D C     K+ G C  D GSGL+CD  G  T+AGV+SRG+   P  +P V +RVS++  WI   I +N
Sbjct:    4 TQRQKRIIGGDIPRDDEHKWKVSIKGDISVVRKAAVYSASIIKSEKGIYWLVTAAHCFFPSNGVTFIDMSNPALWH--VALTKFDSIYEKHGLKDKAMEKLKSIL-----------KNKLITNDFHVKKIIVHPDYKPVKQTNSNAPIPLDNDIALIKLTDPLPENHPSLIYALDLPESSV---WPETDKSCVVAGWDCRKISNNDNYNSKAVNLKILSNEKCEKLTSKSFLMNTKTDLCVAQSTKENGFCLEDIGSGLVCDRNGKSTLAGVLSRGYSDLPIPFPPVLTRVSSYVNWIKDSIKNN 292          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000077235.1 (SMESG000077235.1)

HSP 1 Score: 250.751 bits (639), Expect = 3.917e-80
Identity = 126/305 (41.31%), Postives = 181/305 (59.34%), Query Frame = 2
Query:  113 SSMEKRIIGGEEAPPDKYRWAVSIKGNVDKLKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVGLTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKIIIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWSVNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSKLYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSDPGGYPAVFSRVSAFKEWIFRVISDN 1027
            +  +KRIIGG+    D+++W VSIKG++  ++ +    ASI+++   + WLVTAAHCF+PS+GVT  +++    WH  V LTK D +Y+KHG+KDK  EK+KS+            K K+ T+D H+ KII+HP Y+P  ++N +    +DNDIAL+KL +PLP +  S +  + LP  SV   WP     C+V GW C K+ N  N  +K   LKI SN +CE        +N  +D C     K+ G C  D GSGL+CD  G  T+AGV+SRG+   P  +P V +RVS++  WI   I +N
Sbjct:   21 TQRQKRIIGGDIPRDDEHKWKVSIKGDISVVRKAAVYSASIIKSEKGIYWLVTAAHCFFPSNGVTFIDMSNPALWH--VALTKFDSIYEKHGLKDKAMEKLKSIL-----------KNKLITNDFHVKKIIVHPDYKPVKQTNSNAPIPLDNDIALIKLTDPLPENHPSLIYALDLPESSV---WPETDKSCVVAGWDCRKISNNDNYNSKAVNLKILSNEKCEKLTSKSFLMNTKTDLCVAQSTKENGFCLEDIGSGLVCDRNGKSTLAGVLSRGYSDLPIPFPPVLTRVSSYVNWIKDSIKNN 309          
The following BLAST results are available for this feature:
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMPRSS34.086e-2330.00transmembrane serine protease 3 [Source:HGNC Symbo... [more]
TMPRSS34.086e-2330.00transmembrane serine protease 3 [Source:HGNC Symbo... [more]
TMPRSS34.337e-2330.00transmembrane serine protease 3 [Source:HGNC Symbo... [more]
TMPRSS29.805e-2227.39transmembrane serine protease 2 [Source:HGNC Symbo... [more]
TMPRSS29.805e-2227.39transmembrane serine protease 2 [Source:HGNC Symbo... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
svh-11.580e-1425.25HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
try-13.759e-1326.00TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mas4.016e-2029.08gene:FBgn0011653 transcript:FBtr0073260[more]
mas4.472e-2029.08gene:FBgn0011653 transcript:FBtr0332659[more]
tpr2.145e-1928.71gene:FBgn0034661 transcript:FBtr0071743[more]
CG60413.599e-1826.21gene:FBgn0029826 transcript:FBtr0070861[more]
CG118361.149e-1626.89gene:FBgn0039272 transcript:FBtr0309271[more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CU062628.11.995e-2628.62trypsin-2-like [Source:NCBI gene;Acc:103908930][more]
zgc:925907.998e-2226.10zgc:92590 [Source:ZFIN;Acc:ZDB-GENE-041024-15][more]
CR352265.15.250e-2125.40pep chromosome:GRCz11:24:21813127:21819010:-1 gene... [more]
tmprss91.242e-2028.57transmembrane serine protease 9 [Source:ZFIN;Acc:Z... [more]
zmp:00000011141.455e-2029.21zmp:0000001114 [Source:ZFIN;Acc:ZDB-GENE-140106-74... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMPRSS92.321e-2229.02transmembrane serine protease 9 [Source:NCBI gene;... [more]
TMPRSS93.650e-2229.02transmembrane serine protease 9 [Source:NCBI gene;... [more]
ENSXETT00000011941.11.330e-2127.96trypsin-like [Source:NCBI gene;Acc:105945798][more]
ENSXETT00000011928.11.625e-2127.96trypsin-like [Source:NCBI gene;Acc:105945798][more]
ENSXETT00000011936.13.904e-2127.63trypsin-like [Source:NCBI gene;Acc:105945798][more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tmprss31.112e-2430.28transmembrane protease, serine 3 [Source:MGI Symbo... [more]
Tmprss31.112e-2430.28transmembrane protease, serine 3 [Source:MGI Symbo... [more]
Tmprss31.125e-2430.77transmembrane protease, serine 3 [Source:MGI Symbo... [more]
Tmprss31.231e-2430.28transmembrane protease, serine 3 [Source:MGI Symbo... [more]
Tmprss21.054e-2226.96transmembrane protease, serine 2 [Source:MGI Symbo... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8K1T0|TMPS3_MOUSE7.779e-2430.28Transmembrane protease serine 3 OS=Mus musculus OX... [more]
sp|Q9JIQ8|TMPS2_MOUSE7.369e-2226.96Transmembrane protease serine 2 OS=Mus musculus OX... [more]
sp|Q2KJ63|KLKB1_BOVIN3.638e-2127.54Plasma kallikrein OS=Bos taurus OX=9913 GN=KLKB1 P... [more]
sp|O15393|TMPS2_HUMAN4.709e-2127.39Transmembrane protease serine 2 OS=Homo sapiens OX... [more]
sp|P57727|TMPS3_HUMAN5.529e-2129.90Transmembrane protease serine 3 OS=Homo sapiens OX... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NYH26.327e-5031.94Mast cell tryptase (Fragment) OS=Schistocephalus s... [more]
A0A4S2MLJ21.565e-4834.70Peptidase S1 domain-containing protein OS=Opisthor... [more]
A0A074Z6751.818e-4734.59Peptidase S1 domain-containing protein OS=Opisthor... [more]
A0A068YHF54.331e-4733.22Subfamily S1A unassigned peptidase S01 family OS=E... [more]
A0A5K3F8T11.262e-4632.80Uncharacterized protein OS=Mesocestoides corti OX=... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000049166.13.149e-2228.62serine protease 56 [Source:NCBI gene;Acc:103021696... [more]
tmprss97.786e-2227.42transmembrane serine protease 9 [Source:ZFIN;Acc:Z... [more]
tmprss58.747e-2227.74transmembrane serine protease 5 [Source:ZFIN;Acc:Z... [more]
ENSAMXT00000017181.21.207e-2127.30trypsin-3-like [Source:NCBI gene;Acc:103044944][more]
ENSAMXT00000030599.11.714e-2125.83trypsin-2-like [Source:NCBI gene;Acc:103029195][more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007992.14.299e-2125.83pep scaffold:Pmarinus_7.0:GL479522:6599:9454:1 gen... [more]
ENSPMAT00000004281.17.274e-2125.50pep scaffold:Pmarinus_7.0:GL479205:9482:14995:-1 g... [more]
ENSPMAT00000010026.17.274e-2125.50pep scaffold:Pmarinus_7.0:GL476399:2596494:2601138... [more]
tmprss3a4.288e-2026.75transmembrane serine protease 3a [Source:ZFIN;Acc:... [more]
ENSPMAT00000004829.11.118e-1925.50pep scaffold:Pmarinus_7.0:GL487651:3325:6603:-1 ge... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO315867.239e-2428.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO442085.838e-2328.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO305061.781e-2126.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO348073.747e-2126.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347714.809e-2127.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000041614.16.193e-2227.22pep primary_assembly:ASM223467v1:8:2529637:2537084... [more]
tryp8.499e-2224.92trypsinogen [Source:NCBI gene;Acc:100125451][more]
ENSORLT00000027744.18.499e-2224.92trypsin-2 [Source:NCBI gene;Acc:101161921][more]
ENSORLT00000040914.11.543e-2127.13pep primary_assembly:ASM223467v1:8:2529365:2537213... [more]
prss12.919e-2126.07trypsin-3 [Source:NCBI gene;Acc:101154931][more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000040907.10.000e+099.69SMESG000040907.1[more]
SMESG000040907.10.000e+099.67SMESG000040907.1[more]
SMESG000077268.12.660e-12855.80SMESG000077268.1[more]
SMESG000077235.12.344e-8041.31SMESG000077235.1[more]
SMESG000077235.13.917e-8041.31SMESG000077235.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032940 ID=SMED30032940|Name=Peptidase S1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1352bp
GAAATAATAGTATAAATTATTCATTGAATTAGAATTTTCTGAATTCACAA
AAATGAAAAATACCATTTATCAATTCTTAATAGCATTCATTTTTTGTGTT
ACATGTACTCATTCATCGATGGAGAAAAGGATAATAGGAGGTGAAGAAGC
CCCTCCAGACAAATACAGATGGGCTGTTTCAATCAAAGGTAATGTAGATA
AGTTGAAAATGTCTGGAGCGTGTGGGGCGTCAATTTTACAAACCCCTGGT
CAAGTGCTTTGGTTAGTCACTGCTGCACATTGTTTTTATCCATCAGACGG
AGTTACTGTTTACAATTTGACAAAAGGGAAATATTGGCATGCTCGAGTAG
GTCTGACAAAAGTCGATTTCCTTTATCAAAAGCATGGCATGAAAGATAAA
TTCAAAGAAAAAGTTAAATCCCTTTTTAACAAAGCTTACAGAAAGTTATT
TGGAAAAGACAAGTTCAAGGTCACAACTGATGATCTCCATATTAGTAAAA
TCATAATTCATCCGGGATATCAGCCAGCTGTAAAATCAAATGACGATGGA
ATGTTTCGAATGGATAACGACATAGCTTTGATGAAATTGAAAGAACCTCT
CCCAATTCACCAGTTATCTGGGGTCAGTACAATCGGCTTACCAAATTGGT
CTGTTAATTCCAGTTGGCCCGCGATTGGGTCGGATTGTATTGTTGTTGGA
TGGGGATGCACTAAAGTTAAAAATGCTCCAAATCCGATAGCAAAACTGGC
TATATTAAAAATATGGAGCAATTCTGAATGTGAAAACTCGGTACCATCGA
AATTATACATAAATCCAGCGAGTGATTTCTGTGCAGGATACCTAAAGAAA
AAATACGGTCTGTGCCATGGAGACAGTGGCAGCGGGTTGATATGTGATTA
CCAAGGAACCCCGACTATTGCGGGAGTCGTTTCAAGGGGACACGGATCAG
ATCCTGGAGGATATCCAGCAGTATTCTCAAGAGTTTCAGCTTTCAAGGAG
TGGATTTTCAGAGTCATCAGTGACAATAAATAACCACTAAATTATAAATC
GGTTTAGGGAATATAATTCAGCAAAACTTTCAATATTTTGTCATTTATTC
TTAACTTAATTTTATTATAATTAATAAAATGAAAAACTTTATTAGGCCAT
TTTAGCCATTGAATAAGAGAAATATTTGTTATAAAATTATGATAAAATGA
TAATGAATGAATGCTGACTGACCCCTCTGGGTGACTTCTTGTTGACTTCC
GGCTTCATGCCGTTTATTCTTGACTCGATAAATATTTGCTAGAAAAATTA
GAGAGAAATCGAGTGCTAATGGTTGGTTTGTAAATAAAGAGTTGTTTATA
GA
back to top

protein sequence of SMED30032940-orf-1

>SMED30032940-orf-1 ID=SMED30032940-orf-1|Name=SMED30032940-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=327bp
MKNTIYQFLIAFIFCVTCTHSSMEKRIIGGEEAPPDKYRWAVSIKGNVDK
LKMSGACGASILQTPGQVLWLVTAAHCFYPSDGVTVYNLTKGKYWHARVG
LTKVDFLYQKHGMKDKFKEKVKSLFNKAYRKLFGKDKFKVTTDDLHISKI
IIHPGYQPAVKSNDDGMFRMDNDIALMKLKEPLPIHQLSGVSTIGLPNWS
VNSSWPAIGSDCIVVGWGCTKVKNAPNPIAKLAILKIWSNSECENSVPSK
LYINPASDFCAGYLKKKYGLCHGDSGSGLICDYQGTPTIAGVVSRGHGSD
PGGYPAVFSRVSAFKEWIFRVISDNK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR001314Peptidase_S1A
IPR001254Trypsin_dom
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0008233peptidase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 324..326
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 18..322
e-value: 4.3E-48
score: 165.8
NoneNo IPR availablePANTHERPTHR24256TRANSMEMBRANE PROTEASE, SERINEcoord: 23..322
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.613
IPR001314Peptidase S1A, chymotrypsin familyPRINTSPR00722CHYMOTRYPSINcoord: 268..280
score: 44.58
coord: 169..183
score: 41.27
coord: 62..77
score: 35.57
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 26..318
e-value: 2.5E-44
score: 163.2
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 27..86
e-value: 9.1E-5
score: 22.4
coord: 127..318
e-value: 6.7E-29
score: 101.3
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 27..323
score: 24.653
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 27..318
e-value: 1.30468E-48
score: 160.905
IPR018114Serine proteases, trypsin family, histidine active sitePROSITEPS00134TRYPSIN_HIScoord: 72..77
IPR009003Peptidase S1, PA clanSUPERFAMILYSSF50494Trypsin-like serine proteasescoord: 12..324