Protein kinase domain-containing protein

Overview
NameProtein kinase domain-containing protein
Smed IDSMED30032932
Length (bp)1733
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase domain-containing protein (SMED30032932) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30032932) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase domain-containing protein (SMED30032932) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30032932) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032932

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30032932SMESG000065913.1 SmedASXL_012171SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30032932SMESG000065913.1 SmedASXL_012173SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30032932SMESG000065913.1 SmedASXL_012172SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
gutSMED30032932SMESG000066720.1 SMESG000065914.1 SMESG000065913.1 SMESG000044801.1 SMESG000021895.1 Contig36405newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30032932SMESG000066720.1 SMESG000065914.1 SMESG000065913.1 SMESG000044801.1 SMESG000021895.1 Contig36405uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
zeta neoblastSMED30032932SMESG000065913.1 dd_Smed_v4_22191_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NRBP1 (nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993])

HSP 1 Score: 79.337 bits (194), Expect = 6.333e-15
Identity = 51/163 (31.29%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NRBP1 (nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993])

HSP 1 Score: 79.337 bits (194), Expect = 6.333e-15
Identity = 51/163 (31.29%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NRBP1 (nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993])

HSP 1 Score: 77.7962 bits (190), Expect = 2.025e-14
Identity = 51/166 (30.72%), Postives = 93/166 (56.02%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSNGNP 711
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG     +F+N  P
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAP 231
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NRBP2 (nuclear receptor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19339])

HSP 1 Score: 77.0258 bits (188), Expect = 3.240e-14
Identity = 52/178 (29.21%), Postives = 95/178 (53.37%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLN---KVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNGNP 711
            I+E+SP   + KR     Q N+  + S+ LA++ + G +V+WNE++          ++    +  +L   +HP I+K ++ W+  +E   R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA++FL      I +  +T++ I  Q N  IKIG     +FSN  P
Sbjct:   28 ILEESPCGRWQKRREQVNQGNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI-FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALP 204
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NRBP2 (nuclear receptor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19339])

HSP 1 Score: 68.9366 bits (167), Expect = 1.570e-12
Identity = 44/154 (28.57%), Postives = 83/154 (53.90%), Query Frame = 1 
Query:  268 IDSSSLAIEPKTGKQVIWNEIYLN---KVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNGNP 711
            + S+ LA++ + G +V+WNE++          ++    +  +L   +HP I+K ++ W+  +E   R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA++FL      I +  +T++ I  Q N  IKIG     +FSN  P
Sbjct:    4 LQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLHKYWLDTSEACARVI-FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALP 156
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: hpo-11 (pep chromosome:WBcel235:I:7140278:7147230:-1 gene:WBGene00010427.1 transcript:H37N21.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:hpo-11)

HSP 1 Score: 68.9366 bits (167), Expect = 5.162e-12
Identity = 54/175 (30.86%), Postives = 89/175 (50.86%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKR-NRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAID 690
            I+E+SP   + KR  ++  ++V  ID + LA++ +TG +V+WNE+  +    E+KNF         +   L Q  H  ++KF++ W        R I FITE ++  +   ++  T+ +       +WKK T Q+LSA+ +L   D  I +  +T   +  Q N  IKIG  A D
Sbjct:   32 ILEESPDKRWSKRREQVKQRDVPGIDVAYLAMDNETGNEVVWNEVQFS----ERKNFRAQEEKINAVFDNLTQLVHTNLVKFHKYWTDSKSEKPRII-FITEYMSSGSMSAFLQRTRKAGSSLSIKAWKKWTTQILSALNYLHSSDPPIIHGNLTCNTVFIQQNGLIKIGCVAPD 201
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: wnk-1 (Serine/threonine-protein kinase WNK [Source:UniProtKB/Swiss-Prot;Acc:X5M5N0])

HSP 1 Score: 58.9214 bits (141), Expect = 9.176e-9
Identity = 46/156 (29.49%), Postives = 82/156 (52.56%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKVD-IEKKNFLEIISRLRQFNHPFILKFYESWISINENGERK-INFITERITIPTFREYITHTKLSQRLNDKT--SWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFG 735
             ++ +TG  V W E+  +K++  E++ F E    L+   HP I++FY+ W S +  G+RK I  +TE +T  T + Y+   K   R+N K   SW +   Q+L  ++FL  R+  + + ++  +NI  +  T  + +G + L +  N S + S  G
Sbjct:  349 GLDTETGVAVAWCELQESKLNKTERQRFREEAEMLKDLQHPNIVRFYDYWESADLCGKRKYIVLVTELMTSGTLKMYLKRFK---RINIKVLKSWCR---QILKGLSFLHTRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLATLKNKSFAKSVIG 498
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: wnk-1 (Serine/threonine-protein kinase WNK [Source:UniProtKB/Swiss-Prot;Acc:X5M5N0])

HSP 1 Score: 58.9214 bits (141), Expect = 9.247e-9
Identity = 46/156 (29.49%), Postives = 82/156 (52.56%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKVD-IEKKNFLEIISRLRQFNHPFILKFYESWISINENGERK-INFITERITIPTFREYITHTKLSQRLNDKT--SWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFG 735
             ++ +TG  V W E+  +K++  E++ F E    L+   HP I++FY+ W S +  G+RK I  +TE +T  T + Y+   K   R+N K   SW +   Q+L  ++FL  R+  + + ++  +NI  +  T  + +G + L +  N S + S  G
Sbjct:  349 GLDTETGVAVAWCELQESKLNKTERQRFREEAEMLKDLQHPNIVRFYDYWESADLCGKRKYIVLVTELMTSGTLKMYLKRFK---RINIKVLKSWCR---QILKGLSFLHTRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLATLKNKSFAKSVIG 498
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: wnk-1 (Serine/threonine-protein kinase WNK [Source:UniProtKB/Swiss-Prot;Acc:X5M5N0])

HSP 1 Score: 58.9214 bits (141), Expect = 9.257e-9
Identity = 46/156 (29.49%), Postives = 82/156 (52.56%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKVD-IEKKNFLEIISRLRQFNHPFILKFYESWISINENGERK-INFITERITIPTFREYITHTKLSQRLNDKT--SWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFG 735
             ++ +TG  V W E+  +K++  E++ F E    L+   HP I++FY+ W S +  G+RK I  +TE +T  T + Y+   K   R+N K   SW +   Q+L  ++FL  R+  + + ++  +NI  +  T  + +G + L +  N S + S  G
Sbjct:  296 GLDTETGVAVAWCELQESKLNKTERQRFREEAEMLKDLQHPNIVRFYDYWESADLCGKRKYIVLVTELMTSGTLKMYLKRFK---RINIKVLKSWCR---QILKGLSFLHTRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLATLKNKSFAKSVIG 445
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: wnk-1 (Serine/threonine-protein kinase WNK [Source:UniProtKB/Swiss-Prot;Acc:X5M5N0])

HSP 1 Score: 58.9214 bits (141), Expect = 9.293e-9
Identity = 46/156 (29.49%), Postives = 82/156 (52.56%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKVD-IEKKNFLEIISRLRQFNHPFILKFYESWISINENGERK-INFITERITIPTFREYITHTKLSQRLNDKT--SWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFG 735
             ++ +TG  V W E+  +K++  E++ F E    L+   HP I++FY+ W S +  G+RK I  +TE +T  T + Y+   K   R+N K   SW +   Q+L  ++FL  R+  + + ++  +NI  +  T  + +G + L +  N S + S  G
Sbjct:  349 GLDTETGVAVAWCELQESKLNKTERQRFREEAEMLKDLQHPNIVRFYDYWESADLCGKRKYIVLVTELMTSGTLKMYLKRFK---RINIKVLKSWCR---QILKGLSFLHTRNPPVIHRDLKCDNIFITGTTGSVKIGDLGLATLKNKSFAKSVIG 498
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Madm (gene:FBgn0027497 transcript:FBtr0347493)

HSP 1 Score: 72.4034 bits (176), Expect = 5.193e-13
Identity = 95/374 (25.40%), Postives = 172/374 (45.99%), Query Frame = 1 
Query:  199 IIEKSPSLEF-HKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIY---LNKVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNG-------------------NPSKSFSD----------FGKLILEMCAYHHHLDIQ-SNLQSNDI-DTMLERVIF---ND-QKDFI---VSSMTENRFS--NLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCR-KNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            I+E+SP   +  +R  +  ++V  ID   LA++ + G +V+WNE+    L ++  +++   ++   L Q +H  I+KF+  W    +    ++ FITE ++  + ++++  TK + +     SW++   Q+LSA+++L      I +  +T ++I  Q N  +KIG    D                         P    +D          FG   LEM A    L+IQ SN +S  I +  ++R IF   ND Q+D I   ++   ++R S  +LL  FH  L + V SLK+L    LV + ++   F+         + FD L+     ++  D V+ + R     E+  +  +   A   L KF++D++
Sbjct:   96 ILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQHNGLVKIGSVVPDAVHYSVRRGRERERERERGAHYFQAPEYGAADQLTAALDIYAFGMCALEMAA----LEIQPSNSESTAINEETIQRTIFSLENDLQRDLIRKCLNPQPQDRPSANDLL--FHPLLFE-VHSLKLLTAHCLVFSPANRTMFS--------ETAFDGLMQR---YYQPDVVMAQLRLAGGQERQYRLADVSGA-DKLEKFVEDVK 450
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Madm (gene:FBgn0027497 transcript:FBtr0078722)

HSP 1 Score: 72.4034 bits (176), Expect = 5.193e-13
Identity = 95/374 (25.40%), Postives = 172/374 (45.99%), Query Frame = 1 
Query:  199 IIEKSPSLEF-HKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIY---LNKVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNG-------------------NPSKSFSD----------FGKLILEMCAYHHHLDIQ-SNLQSNDI-DTMLERVIF---ND-QKDFI---VSSMTENRFS--NLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCR-KNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            I+E+SP   +  +R  +  ++V  ID   LA++ + G +V+WNE+    L ++  +++   ++   L Q +H  I+KF+  W    +    ++ FITE ++  + ++++  TK + +     SW++   Q+LSA+++L      I +  +T ++I  Q N  +KIG    D                         P    +D          FG   LEM A    L+IQ SN +S  I +  ++R IF   ND Q+D I   ++   ++R S  +LL  FH  L + V SLK+L    LV + ++   F+         + FD L+     ++  D V+ + R     E+  +  +   A   L KF++D++
Sbjct:   96 ILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQHNGLVKIGSVVPDAVHYSVRRGRERERERERGAHYFQAPEYGAADQLTAALDIYAFGMCALEMAA----LEIQPSNSESTAINEETIQRTIFSLENDLQRDLIRKCLNPQPQDRPSANDLL--FHPLLFE-VHSLKLLTAHCLVFSPANRTMFS--------ETAFDGLMQR---YYQPDVVMAQLRLAGGQERQYRLADVSGA-DKLEKFVEDVK 450
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nrbp2b (nuclear receptor binding protein 2b [Source:ZFIN;Acc:ZDB-GENE-080724-1])

HSP 1 Score: 83.9593 bits (206), Expect = 1.223e-16
Identity = 58/183 (31.69%), Postives = 97/183 (53.01%), Query Frame = 1 
Query:  214 PSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKK---NFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSNGNPSKSFSDFGKL 741
            P   + KR     Q NV  ++S+SLA++ + G +V+WNE++     + K       E+   L Q +HP I+KF++ W+ I +N  R + FITE ++  + ++++  TK + +  +  +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG     LF N  P       GKL
Sbjct:   30 PCGRWQKRKEQVSQGNVPGVESASLAMDTEEGVEVVWNEVFFQDKKVFKTVEDKMKEMFENLTQVDHPNIVKFHKYWLDIRDNHARVV-FITEYMSSGSLKQFLKKTKKNHKTMNVKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVWHRLFVNVFPEGGVQ--GKL 209
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nrbp2a (nuclear receptor binding protein 2a [Source:ZFIN;Acc:ZDB-GENE-070713-4])

HSP 1 Score: 82.4185 bits (202), Expect = 2.715e-16
Identity = 85/294 (28.91%), Postives = 140/294 (47.62%), Query Frame = 1 
Query:  235 RNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEK---KNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSNGNPSKS-----------FSD---------FGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQ-------KDFIVSSM-TENRFSNLLNN--FHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENC 1008
            R R    NV  I+S+ LA++ + G +V+WNE+  +   + K   +   E+   L Q  HP I+KF++ W+ + E+  R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG     LF NG    S           F++         FG   LEM      L+IQ+N    D     E + +  Q       ++FI S + TE +     ++  FH  L + V SLK+LA    ++     N + + ENC
Sbjct:   39 RRRQNQGNVPGIESAYLAMDTEEGVEVVWNEVQFSDKKVFKSFEERIREMFENLMQVEHPNIVKFHKYWLDMRESRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNVKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVWHRLFVNGESISSSICHVHRNVVIFAEDNYAIDIFSFGICGLEMAV----LEIQAN---GDTAVAKEAIDYAGQSLEDPLMREFIQSCVRTEAKSRPTAHDLLFHRVLFE-VHSLKLLAAHCFIN-----NQYLLPENC 318
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nrbp2a (nuclear receptor binding protein 2a [Source:ZFIN;Acc:ZDB-GENE-070713-4])

HSP 1 Score: 78.9518 bits (193), Expect = 4.463e-15
Identity = 80/308 (25.97%), Postives = 140/308 (45.45%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEK---KNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRD------------------------IGIANSEITNENIHQSNCTIK--------IGLG----AIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQ-------KDFIVSSM-TENRFSNLLNN--FHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENC 1008
            +R ++   NV  I+S+ LA++ + G +V+WNE+  +   + K   +   E+   L Q  HP I+KF++ W+ + E+  R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA+++L                          IG   +E  + N+HQ    ++         G+     AID+FS          FG   LEM      L+IQ+N    D     E + +  Q       ++FI S + TE +     ++  FH  L + V SLK+LA    ++     N + + ENC
Sbjct:   37 RREQVSQGNVPGIESAYLAMDTEEGVEVVWNEVQFSDKKVFKSFEERIREMFENLMQVEHPNIVKFHKYWLDMRESRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNVKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFAEAIHGNVHQHRDEVRNQHFFAPEYGIAEDNYAIDIFS----------FGICGLEMAV----LEIQAN---GDTAVAKEAIDYAGQSLEDPLMREFIQSCVRTEAKSRPTAHDLLFHRVLFE-VHSLKLLAAHCFIN-----NQYLLPENC 320
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nrbp1 (nuclear receptor binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-041001-146])

HSP 1 Score: 77.7962 bits (190), Expect = 1.256e-14
Identity = 99/355 (27.89%), Postives = 166/355 (46.76%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN-----GNPSKSF----SDFGKLI----------LEMCAYHHH-LDIQSNLQSN-----DIDTMLERVIFNDQKDFI-----VSSMTENRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            +R  +  +NV  ID++ LA++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   +  I +  +T + I  Q N  IKIG  A D  +N         KS      ++G +             MCA     L+IQSN +S+      I++ ++ +    Q++FI     V          LL  FH  L + V  LK+LA   +V   SH +   I EN           L     + D + VI++ ++N L KL ++    L      KFL+D+R
Sbjct:   60 RREEVNQRNVPGIDNAYLAMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCEPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKSLHFFAPEYGAVANVTTAVDIYSFGMCALEMAVLEIQSNGESSYVSQEAINSAIQSLEDPLQREFIQKCLEVDPSKRPTARELL--FHQALFE-VPQLKLLAAHCIV---SHQHM--IPENA----------LEEITKNMDPNQVIMERKENQL-KLSQFPALELD-----KFLEDVR 385
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nrbp1 (nuclear receptor binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-041001-146])

HSP 1 Score: 77.411 bits (189), Expect = 1.419e-14
Identity = 99/355 (27.89%), Postives = 166/355 (46.76%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN-----GNPSKSF----SDFGKLI----------LEMCAYHHH-LDIQSNLQSN-----DIDTMLERVIFNDQKDFI-----VSSMTENRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            +R  +  +NV  ID++ LA++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   +  I +  +T + I  Q N  IKIG  A D  +N         KS      ++G +             MCA     L+IQSN +S+      I++ ++ +    Q++FI     V          LL  FH  L + V  LK+LA   +V   SH +   I EN           L     + D + VI++ ++N L KL ++    L      KFL+D+R
Sbjct:   76 RREEVNQRNVPGIDNAYLAMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCEPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKSLHFFAPEYGAVANVTTAVDIYSFGMCALEMAVLEIQSNGESSYVSQEAINSAIQSLEDPLQREFIQKCLEVDPSKRPTARELL--FHQALFE-VPQLKLLAAHCIV---SHQHM--IPENA----------LEEITKNMDPNQVIMERKENQL-KLSQFPALELD-----KFLEDVR 401
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nrbp1 (nuclear receptor binding protein 1 [Source:MGI Symbol;Acc:MGI:2183436])

HSP 1 Score: 78.9518 bits (193), Expect = 6.347e-15
Identity = 50/163 (30.67%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nrbp2 (nuclear receptor binding protein 2 [Source:MGI Symbol;Acc:MGI:2385017])

HSP 1 Score: 78.5666 bits (192), Expect = 7.208e-15
Identity = 92/373 (24.66%), Postives = 165/373 (44.24%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLN---KVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNGNPSKSFSD-------------------------------FGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFN----DQKDFIVSSMTEN---RFS--NLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            I+E+SP   + KR     Q N+  I S+ LA++ + G +V+WNE++          ++    +  +L   +HP I+K ++ W+  +E   R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA++FL      I +  +T++ I  Q N  IKIG     +FSN  P    S                                FG   LEM      L+IQ+N  +   +  + R   +    + ++FI+S +  +   R S  NLL  FH  L + V SLK+LA    + +        ++E  +++               D  +V+ +  +      ++W    ++F  L KFL+D+R
Sbjct:   26 ILEESPCGRWQKRREQVNQGNMPGIQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTMFEQLALVDHPNIVKLHKYWLDASEARARVI-FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDTIFIQHNGLIKIGSVWYRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVNDGTAVDIFSFGMCALEMAV----LEIQANGDTRVTEEAIARARHSLSDPNMREFILSCLARDPARRPSAHNLL--FHRVLFE-VHSLKLLAAHCFIQHQYLMPENVVEEKTKAM---------------DLHAVLAEMPQPHGPP-MQWRYSEVSFLELDKFLEDVR 374
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nrbp1 (nuclear receptor binding protein 1 [Source:MGI Symbol;Acc:MGI:2183436])

HSP 1 Score: 77.411 bits (189), Expect = 1.717e-14
Identity = 50/166 (30.12%), Postives = 93/166 (56.02%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSNGNP 711
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG     +F+N  P
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAP 231
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nrbp1 (nuclear receptor binding protein 1 [Source:MGI Symbol;Acc:MGI:2183436])

HSP 1 Score: 66.2402 bits (160), Expect = 4.396e-12
Identity = 42/144 (29.17%), Postives = 80/144 (55.56%), Query Frame = 1 
Query:  289 IEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            ++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:    1 MDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 143
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nrbp2 (nuclear receptor binding protein 2 [Source:MGI Symbol;Acc:MGI:2385017])

HSP 1 Score: 53.1434 bits (126), Expect = 1.006e-7
Identity = 33/124 (26.61%), Postives = 65/124 (52.42%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLN---KVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSW 558
            I+E+SP   + KR     Q N+  I S+ LA++ + G +V+WNE++          ++    +  +L   +HP I+K ++ W+  +E   R I FITE ++  + ++++  TK + +  +   W
Sbjct:   26 ILEESPCGRWQKRREQVNQGNMPGIQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTMFEQLALVDHPNIVKLHKYWLDASEARARVI-FITEYVSSGSLKQFLKKTKKNHKAMNARVW 148
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R8X0|NRBP_MACFA (Nuclear receptor-binding protein OS=Macaca fascicularis OX=9541 GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.042e-14
Identity = 51/163 (31.29%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UHY1|NRBP_HUMAN (Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.042e-14
Identity = 51/163 (31.29%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RBH9|NRBP_PONAB (Nuclear receptor-binding protein OS=Pongo abelii OX=9601 GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.440e-14
Identity = 51/163 (31.29%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99J45|NRBP_MOUSE (Nuclear receptor-binding protein OS=Mus musculus OX=10090 GN=Nrbp1 PE=1 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 4.440e-14
Identity = 50/163 (30.67%), Postives = 92/163 (56.44%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  ++     ++++    +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   67 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 228
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q91V36|NRBP2_MOUSE (Nuclear receptor-binding protein 2 OS=Mus musculus OX=10090 GN=Nrbp2 PE=1 SV=2)

HSP 1 Score: 78.5666 bits (192), Expect = 5.042e-14
Identity = 92/373 (24.66%), Postives = 165/373 (44.24%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLN---KVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIG--IANSEITNENIH-QSNCTIKIGLGAIDLFSNGNPSKSFSD-------------------------------FGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFN----DQKDFIVSSMTEN---RFS--NLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            I+E+SP   + KR     Q N+  I S+ LA++ + G +V+WNE++          ++    +  +L   +HP I+K ++ W+  +E   R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA++FL      I +  +T++ I  Q N  IKIG     +FSN  P    S                                FG   LEM      L+IQ+N  +   +  + R   +    + ++FI+S +  +   R S  NLL  FH  L + V SLK+LA    + +        ++E  +++               D  +V+ +  +      ++W    ++F  L KFL+D+R
Sbjct:   26 ILEESPCGRWQKRREQVNQGNMPGIQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTMFEQLALVDHPNIVKLHKYWLDASEARARVI-FITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHACSPPIIHGNLTSDTIFIQHNGLIKIGSVWYRIFSNALPDDLRSPIRAEREELRNLHFFPPEYGEVNDGTAVDIFSFGMCALEMAV----LEIQANGDTRVTEEAIARARHSLSDPNMREFILSCLARDPARRPSAHNLL--FHRVLFE-VHSLKLLAAHCFIQHQYLMPENVVEEKTKAM---------------DLHAVLAEMPQPHGPP-MQWRYSEVSFLELDKFLEDVR 374
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A3P7PV61 (Protein kinase domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS14306 PE=4 SV=1)

HSP 1 Score: 162.155 bits (409), Expect = 9.185e-40
Identity = 111/354 (31.36%), Postives = 190/354 (53.67%), Query Frame = 1 
Query:  226 FHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAID-LFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTENRFSN-----LLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIK-----ENCRSIYSP-FDDLLGSHIDHFDNDSVIVKC--RKNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIF 1239
            FHKRN+ + + V  +D + +AIEPK+GK+VIWNE  L +   E++N FL ++ +L++  HPF+++F ++WI+  + G RKI FITER+   T ++Y+ +   ++ L     W++  GQLLS + FL  +G+ +  +T E I +Q++  +K+G   +D  F   + +      G + LE+ A+   LD  +   +  +  ML+R+    Q++FI   +  N  S      LLN  H  L + V +LK+L+ K LV     T  FA++     E   +  +P F  LL  ++ H ++++VIV+     + +     W++F   FT+  KFL+D+              +NGFY  F
Sbjct:   60 FHKRNKRFPKQVAGVDDTFIAIEPKSGKEVIWNERILPEKKTERENRFLAVVKKLKRHAHPFLVRFLDAWITKGDCGPRKIVFITERLDECTLKQYLCNATRTKLL-----WRRHIGQLLSVVIFLHHLGVTHGNLTKETIYYQNSGCLKVGPFVLDGFFGQRSLATDILALGLVALEIAAWTPALDAANLPAAERLPQMLDRLQDPHQRNFIEICLDPNPASRPRIKFLLN--HPSLAE-VPTLKLLSAKVLVGT---TLLFAVRAAGPAEEAVATEAPGFATLLKDNLSHLEDETVIVETTFPHDQVSHSRSWKDFRSNFTLTSKFLEDV--------------KNGFYPFF 388
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A3R7CYA6 (Nuclear receptor-binding protein OS=Clonorchis sinensis OX=79923 GN=Nrbp1 PE=4 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 1.454e-38
Identity = 112/363 (30.85%), Postives = 202/363 (55.65%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAIDLFSNGNP------SKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTE-----NRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNI-SHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCR--KNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIF 1239
            I+EKS +  FHKRN+ +   ++ +DS+ +AIEPK+GK+VIWNE  L++   EK+N +L I+ RL++ +HPF+ ++ ++W++ +++G RK+ FITER+   T ++++ ++  + R     SWK+  GQLLS + FL  +G+ +  +T E I +Q++  +++G      FS G P      S      G + LE+  +      Q+ L +     M  R+  +DQ+ FI S +       NR   L++  H  + ++ I LK+L+ K +V  + S TN    +E   +  + F  LL  ++ H+++++VIV+     +++ K   W++F   FT+  K+L+D+              +NGFY +F
Sbjct:   56 IVEKSHNSRFHKRNKRFPIQIQGVDSAFVAIEPKSGKEVIWNECILSEKKSEKENRYLSIMKRLKRNSHPFLARYLDAWVAKSDDGPRKLVFITERLDECTLKQFLCNSPKNNR-----SWKRHVGQLLSVLMFLHRLGVPHGNLTKETIYYQNSGNLRVG-----PFSLGGPLDQKSQSADVYALGVVALEIAVWTPTEFPQTLLPAELCQQMQARLENSDQRSFIESCLDPNPTMGNRVKRLIH--HPAVTEVPI-LKLLSAKVIVGALRSVTN----EEGSATEQTGFASLLKEYVSHYEDETVIVEVHFPHDNIVKSRSWKDFRSNFTLTSKYLEDV--------------KNGFYPLF 387
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A4V3SD12 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009369 PE=4 SV=1)

HSP 1 Score: 162.155 bits (409), Expect = 3.517e-38
Identity = 112/363 (30.85%), Postives = 201/363 (55.37%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAIDLFSNGNP------SKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTE-----NRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNI-SHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCR--KNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIF 1239
            I+EKS +  FHKRN+ +   ++ +DS+ +AIEPK+GK+VIWNE  L++   EK+N +L I+ RL++ +HPF+ ++ ++W++ +++G RK+ FITER+   T ++++ ++  + R     SWK+  GQLLS + FL  +GI +  +T E I +Q++  +++G      FS G P      S      G + LE+  +      Q+ L +     M  R+  +DQ+ FI   +       NR   L++  H  + ++ I LK+L+ K +V  + S TN    +E   +  + F  LL  ++ H+++++VIV+     +++ K   W++F   FT+  K+L+D+              +NGFY +F
Sbjct:   56 IVEKSHNSRFHKRNKRFPIQIQGVDSAFVAIEPKSGKEVIWNECILSEKKSEKENRYLSIMKRLKRNSHPFLARYLDAWVAKSDDGSRKLVFITERLDECTLKQFLCNSPKNNR-----SWKRHVGQLLSVLMFLHRLGIPHGNLTKETIYYQNSGNLRVG-----PFSLGGPLDQKSQSADVYALGVVALEIAVWTPTEFPQTLLPAELCQQMQARLENSDQRSFIECCLDPNPAVGNRVKRLIH--HPAVTEVPI-LKLLSAKVIVGALRSVTN----EEGSATEQTGFASLLKEYVSHYEDETVIVEVHFPHDNIVKSRSWKDFRSNFTLTSKYLEDV--------------KNGFYPLF 387
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A2H1C048 (Protein kinase domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_12321 PE=4 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 2.952e-37
Identity = 101/343 (29.45%), Postives = 198/343 (57.73%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAI-DLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTEN-----RFSNLLNNFHVKLQKLVISLKVLAGKKLVD-NISHTNTFAI-----KENCRSI-YSPFDDLLGSHIDHFDNDSVIVKCR--KNSLEKLLKWENFLLAFTILPKFLDDIR 1176
            I+EKS +  FHKRN+ + + ++ +D++ +AIEPK+GK+VIWNE  L++   +K+N +L II +L++ +HPF+ +F ++W+S +E+G RK+ FITER+   + ++++ ++  + RL     WK+  GQ+LS + FL  +GI +  ++ E+I +Q++  +++G  A+     + + S      G + LE+  +      QS   +     M+ ++    Q+DFI   +  N     +   L+N  H  + ++ I LK+L+ K +V+ NI++  +F +      E+C +   + F  LL  ++ H++++++IV      +++     W++F   FT+  KFL+D +
Sbjct:   49 IVEKSHNSRFHKRNKRFPKQIEGVDNAFIAIEPKSGKEVIWNECILSEKKTDKENRYLSIIKKLKKSSHPFLARFLDAWVSKSEDGSRKLVFITERLDECSLKQFLCNSAKNNRL-----WKRHVGQILSVLMFLHRLGITHGNLSKESIYYQNSGNLRVGPFALGGCLDHKSLSADIYALGVVALEIAIWTPTEFPQSLPLTERCQQMIAKLEDCSQRDFIEVCLDSNINARHKMKRLIN--HPAVTEVPI-LKLLSAKVIVENNINYRCSFLVVKSLTNEDCPAAEQTGFTTLLKDYLSHYEDETIIVDVHFPHDNVVNSRSWKDFRSNFTLTSKFLEDFK 383
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A4Z2DBA6 (Nuclear receptor-binding protein OS=Schistosoma japonicum OX=6182 GN=EWB00_002685 PE=4 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 4.882e-36
Identity = 105/358 (29.33%), Postives = 205/358 (57.26%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAIDLFSNGNPSKSFS--DFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVS-----SMTENRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCR--KNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIF 1239
            I+EKS +  FHKRN+ + + ++ +D++ +AIEPK+GK+VIWNE  L +   +K+N +L +I +L++ +HPF+++F ++W+S  E G RK+ FITER+   T ++++ ++  + RL     W +  GQLLS + FL  +G+A+  +T E+I +Q++  +++GL A+    +   S++F     G + LE+  +      Q+   +     M+ R+  ++QK FI +     S T+     LLN+  V     V +LK+L+ + +V+++  T++   ++   +  + F  LL  +++ +++++VI++     + + K   W++F   FT+  K+L+D+              +NGFY +F
Sbjct:   49 IVEKSHNSRFHKRNKRFPKQIEGVDNAFVAIEPKSGKEVIWNECILPEKKTDKENRYLSLIKKLKKNSHPFLVRFLDAWVSKTEEGPRKLVFITERLDECTLKQFLCNSAKNNRL-----WNRHVGQLLSVLMFLHRLGVAHGNLTKESIYYQNSGNLRVGLFALGRCLDQK-SEAFDVYSLGVVSLEIAVWTPTEFPQNADLAERCQQMISRLDNSNQKSFIEACFDTVSATKGLIKRLLNHPAV---TEVPTLKLLSARMIVNSMISTSS---EDGSTNEPTGFVSLLKEYLNRYEDETVIMEVHFPHDGVVKSKSWKDFRSNFTLTSKYLEDV--------------KNGFYPLF 380
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nrbp2a (nuclear receptor binding protein 2a [Source:ZFIN;Acc:ZDB-GENE-070713-4])

HSP 1 Score: 86.6557 bits (213), Expect = 1.447e-17
Identity = 55/171 (32.16%), Postives = 93/171 (54.39%), Query Frame = 1 
Query:  196 LIIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN---FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAID 690
            L I  +P        R+   NV  I+S+SLA++ + G +V+WNE+  +   + K +     E+   L Q  HP I+KF++ W+   EN  R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG GA +
Sbjct:   97 LAIRHAPCGPRRWNPRVSQGNVPGIESASLAMDTEEGVEVVWNEVQFSDKKVFKAHEDRIKEMFENLMQVEHPNIVKFHKYWLDTRENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNVKAWKRWCTQILSALSYLHSCDPPIVHGNLTCDTIFIQHNGLIKIGSGAAE 266
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nrbp1 (nuclear receptor binding protein 1 [Source:NCBI gene;Acc:103045477])

HSP 1 Score: 76.2554 bits (186), Expect = 3.328e-14
Identity = 52/167 (31.14%), Postives = 92/167 (55.09%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  ID++ LA++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   +  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   80 RREEVNQRNVPGIDNAYLAMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCEPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 241
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nrbp1 (nuclear receptor binding protein 1 [Source:NCBI gene;Acc:103045477])

HSP 1 Score: 75.8702 bits (185), Expect = 3.541e-14
Identity = 52/167 (31.14%), Postives = 92/167 (55.09%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  ID++ LA++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   +  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   80 RREEVNQRNVPGIDNAYLAMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCEPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 241
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: wnk4b (serine/threonine-protein kinase WNK4-like [Source:NCBI gene;Acc:103036582])

HSP 1 Score: 50.447 bits (119), Expect = 5.438e-6
Identity = 37/139 (26.62%), Postives = 69/139 (49.64%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKV-DIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDL 693
             ++ +T  +V W E+   ++  +E++ F E +  L+   HP I++FY+SW S    G + I  +TE +T  T + Y+   K   +L     W   + Q+L  + FL  R   I + ++  +NI  +  T  + +G + L
Sbjct:  219 GLDTETTVEVAWCELQTRRLTKVERQRFSEEVEMLKGLQHPNIVRFYDSWKS-TVKGHKCIILVTELMTSGTLKTYLKRFK-EMKLKLLQRW---SHQILKGLHFLHTRAPPIIHRDLKCDNIFITGPTGSVKIGDLGL 352
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041214.1 (serine/threonine-protein kinase WNK1 [Source:NCBI gene;Acc:103038802])

HSP 1 Score: 49.6766 bits (117), Expect = 9.024e-6
Identity = 38/139 (27.34%), Postives = 71/139 (51.08%), Query Frame = 1 
Query:  286 AIEPKTGKQVIWNEIYLNKVD-IEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFL--RDIGIANSEITNENIHQSNCTIKIGLGAIDL 693
             ++ +T  +V W E+   K+   E++ F E    L+   HP I++FY+SW S ++ G++ I  +TE +T  T + Y+   K   ++    SW +   Q+L  + FL  R   I + ++  +NI  +  T  + +G + L
Sbjct:  227 GLDTETTVEVAWCELQDRKLSKSERQRFKEEAGMLKGLQHPNIVRFYDSWESPSK-GKKYIVLVTELMTSGTLKTYLKRFK-EMKIKVLRSWCR---QILKGLHFLHTRSPPIIHRDLKCDNIFITGPTGSVKIGDLGL 360
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: nrbp1 (nuclear receptor binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-041001-146])

HSP 1 Score: 81.6481 bits (200), Expect = 1.209e-16
Identity = 55/167 (32.93%), Postives = 90/167 (53.89%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFLE-------IISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRD--IGIANSEITNENI-HQSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  IDS+ LA++ + G +V+WNE+  +    E+KNF         +   L Q  HP I+KF++ W  I EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+ +L      I +  +T + I  Q N  IKIG  A D   N
Sbjct:   48 RREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFS----ERKNFKAQEEKIKAVFDNLIQLEHPNIVKFHKYWTDIKENKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALRYLHSSVPPIIHGNLTCDTIFMQHNGLIKIGSVAPDAIHN 209
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: nrbp1 (nuclear receptor binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-041001-146])

HSP 1 Score: 75.485 bits (184), Expect = 5.522e-15
Identity = 50/166 (30.12%), Postives = 91/166 (54.82%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKR-NRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDI--GIANSEITNENI-HQSNCTIKIG 675
            I+E+SP   + KR   +  +NV  IDS+ L ++ + G +V+WNE+  ++      +++    + + L    H  I+KF+  W  I E+  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+ +L      I ++ +T E I  Q N  IKIG
Sbjct:   27 ILEESPCGRWQKRREEVSQRNVPGIDSAYLGMDTEEGVEVVWNEVQFSERRNYKAQEEKIKTVFNNLIHLEHANIVKFHNYWADIKESKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALGYLHSFVPPIIHANLTCETIFMQHNGLIKIG 191
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: nrbp1 (nuclear receptor binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-041001-146])

HSP 1 Score: 75.0998 bits (183), Expect = 7.101e-15
Identity = 50/166 (30.12%), Postives = 91/166 (54.82%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKR-NRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNK---VDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDI--GIANSEITNENI-HQSNCTIKIG 675
            I+E+SP   + KR   +  +NV  IDS+ L ++ + G +V+WNE+  ++      +++    + + L    H  I+KF+  W  I E+  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+ +L      I ++ +T E I  Q N  IKIG
Sbjct:   28 ILEESPCGRWQKRREEVSQRNVPGIDSAYLGMDTEEGVEVVWNEVQFSERRNYKAQEEKIKTVFNNLIHLEHANIVKFHNYWADIKESKARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALGYLHSFVPPIIHANLTCETIFMQHNGLIKIG 192
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36110 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJJ9])

HSP 1 Score: 81.2629 bits (199), Expect = 2.475e-16
Identity = 73/261 (27.97%), Postives = 120/261 (45.98%), Query Frame = 1 
Query:  208 KSPSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNF-------LEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLS--QRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN-------------------GNPSK------SFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTEN 876
            +SP   + KR +   Q +V  ID + LA++ + G +V+WNE+  +    E+K+F        ++   L Q +HP I+ F+  W  +     R I FITE +T  + ++++  T+ +  + +N+K  WK+   Q+LSA+++L   D+ I +  ++ + I  Q N  IKIG  A D   N                   G P            FG   LEM A   H DI+  +    I   ++ +    QKDFI   + EN
Sbjct:   30 QSPCGRWEKRRQEVMQRDVPGIDHAYLAMDTEEGVEVVWNEVQFS----ERKDFKSQEETVKKVFENLIQLDHPNIVSFHRFWTDVQGEKARVI-FITEYMTSGSLKQFLKKTRKNNYKTMNEKV-WKRWCRQILSALSYLHGCDVPIVHGNLSCDTIFIQHNGLIKIGSVAPDTIHNHVKTCREERRNMHFIAPEYGQPGHIVDCAVDVYAFGMCALEMAALELH-DIEGPVPKEAITQAIQGLESPLQKDFINRCLAEN 283
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nrbp2b (nuclear receptor binding protein 2 [Source:NCBI gene;Acc:101163531])

HSP 1 Score: 85.1149 bits (209), Expect = 4.990e-17
Identity = 61/200 (30.50%), Postives = 103/200 (51.50%), Query Frame = 1 
Query:  214 PSLEFHKRNRIYFQ-NVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDI---EKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNL 792
            P   + KR     Q NV  ++S+SLA++ + G +V+WNE+  +   +   +++   E+   L Q  HP I+KF++ W+ + E+  R I FITE ++  + ++++  TK + +  +  +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG     LF N  P  S    G+          H D Q NL
Sbjct:   30 PCGRWQKRKEQVSQGNVPGVESASLAMDTEEGVEVVWNEVLFSDKKVFKAQEEKIKEMFENLMQVEHPNIVKFHKYWLDMKESQARVI-FITEYMSSGSLKQFLKKTKKNHKTMNVKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVWHRLFVNVFPDTSVHSKGR---------QHRDEQRNL 219
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000014317.2 (nuclear receptor-binding protein [Source:NCBI gene;Acc:101170578])

HSP 1 Score: 79.7221 bits (195), Expect = 2.236e-15
Identity = 52/179 (29.05%), Postives = 103/179 (57.54%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKR-NRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFLEIISRLR-------QFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            ++E+SP   + KR +++  +NV  ID++ LA++ + G +V+WNE+ ++    E+K+F  +  +++          H  I+KF++ W  I ++  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + +  Q N  IKIG  A D  +N
Sbjct:   64 VLEESPCGRWQKRRDQVNQRNVPGIDAAYLAMDTEEGVEVVWNEVMIS----ERKDFKPLQEKVKAVFDNLIHLEHANIVKFHKYWADIKDSRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTVFIQHNGLIKIGSVAPDTINN 237
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nrbp1 (nuclear receptor-binding protein [Source:NCBI gene;Acc:101169578])

HSP 1 Score: 75.8702 bits (185), Expect = 1.456e-14
Identity = 69/236 (29.24%), Postives = 119/236 (50.42%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIG---------LGAID--LFSNGNPSKSFS--DFGKLILEMCAYHHHLDIQSNLQSN-----DIDTMLERVIFNDQKDFI 855
            +R  +  +NV  ID++ L ++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG         L A +  L S  N + +     FG   LEM      L+IQSN  S+      I++ ++ +    Q++FI
Sbjct:   73 RREEVNQRNVPGIDNAYLGMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVITWARMLLKAEEPSLLSVANVTTAVDIYSFGMCALEMAV----LEIQSNGDSSYVSQEAINSAIQSLEDPLQREFI 299
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nrbp1 (nuclear receptor-binding protein [Source:NCBI gene;Acc:101169578])

HSP 1 Score: 77.0258 bits (188), Expect = 1.629e-14
Identity = 52/167 (31.14%), Postives = 91/167 (54.49%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  ID++ L ++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:   73 RREEVNQRNVPGIDNAYLGMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 234
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nrbp1 (nuclear receptor-binding protein [Source:NCBI gene;Acc:101169578])

HSP 1 Score: 77.0258 bits (188), Expect = 2.154e-14
Identity = 52/167 (31.14%), Postives = 91/167 (54.49%), Query Frame = 1 
Query:  232 KRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL-------EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR--DIGIANSEITNENIH-QSNCTIKIGLGAIDLFSN 702
            +R  +  +NV  ID++ L ++ + G +V+WNE+  +    E+KNF         +   L Q  H  I+KF++ W  + EN  R I FITE ++  + ++++  TK + +  ++ +WK+   Q+LSA+++L   D  I +  +T + I  Q N  IKIG  A D  +N
Sbjct:  122 RREEVNQRNVPGIDNAYLGMDTEEGVEVVWNEVMFS----ERKNFKLQEEKVKAVFDNLIQLEHLNIVKFHKYWADVKENRARVI-FITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINN 283
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000065913.1 (SMESG000065913.1)

HSP 1 Score: 734.176 bits (1894), Expect = 0.000e+0
Identity = 385/408 (94.36%), Postives = 389/408 (95.34%), Query Frame = 1 
Query:   70 MKELIHNKPVEVKSIDETSNDIFKILXXXXXXXXXXXXXXXYLIIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTENRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIFTNEYCEIVSNSLELNSGL 1293
            MKELIHNKPVE KSIDETSNDIFKILSNISNENEANSEENEYLIIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKK FLEIISRLRQFNHPFILKFYESWISINE GERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLR+IGIAN EITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTML+RVIFNDQKDFIVSSMTE+RFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDI              RNGFYSIFTNEYCEIVSNSLELNS +
Sbjct:    1 MKELIHNKPVEGKSIDETSNDIFKILSNISNENEANSEENEYLIIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKIFLEIISRLRQFNHPFILKFYESWISINEYGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLREIGIANGEITNENIHQSNCTIKIGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLDRVIFNDQKDFIVSSMTESRFSNLLNNFHVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLKWENFLLAFTILPKFLDDI--------------RNGFYSIFTNEYCEIVSNSLELNSDV 394

HSP 2 Score: 219.55 bits (558), Expect = 0.000e+0
Identity = 131/132 (99.24%), Postives = 131/132 (99.24%), Query Frame = 3 
Query: 1338 DVINLGNDFRVSSDNLIDFDSTXXXXXXXXXXXXXXXXXFIIHEDSSSRESEIKSEQVQNLLNLSVDGETNLIDFRSPVLEKKSLINIPVDESSVNETMFQNLDNLFDKEIIKCRPHDMRIKIESPLDTIPH 1733
            DVINLGNDFRVSSDNLIDFDS LLENEELIKNLEVKEKIFIIHEDSSSRESEIKSEQVQNLLNLSVDGETNLIDFRSPVLEKKSLINIPVDESSVNETMFQNLDNLFDKEIIKCRPHDMRIKIESPLDTIPH
Sbjct:  393 DVINLGNDFRVSSDNLIDFDSALLENEELIKNLEVKEKIFIIHEDSSSRESEIKSEQVQNLLNLSVDGETNLIDFRSPVLEKKSLINIPVDESSVNETMFQNLDNLFDKEIIKCRPHDMRIKIESPLDTIPH 524
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BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000066284.1 (SMESG000066284.1)

HSP 1 Score: 223.787 bits (569), Expect = 9.494e-63
Identity = 133/360 (36.94%), Postives = 209/360 (58.06%), Query Frame = 1 
Query:  199 IIEKSPSLEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKN-FLEIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITHTKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENI-HQSNCTIKIGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTMLERVIFNDQKDFIVSSMTENRFSNLLNNF--HVKLQKLVISLKVLAGKKLVDNISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKC--RKNSLEKLLKWENFLLAFTILPKFLDDIR*VNF*NRLKVM*NRNGFYSIFTNEYCEI 1260
            IIEKSP+L FHKRN+ Y + V  ID+S +AIEPK+GK+VIWNEI L+    E++N F+ +I +L+++NHPF ++F + W S  E+G RK+ F+TER+T PT ++Y  ++  S RL +K+ W+K  GQL+S + FL  +G+ +  ++NE + +Q+   +K+G  ++DL  +  PS    D GKL LEM AY    D +S    + I  ML RV  + Q  FI   +        L+    H+ L K V SLK LA K +V N   T+     EN  S+   F  +    + HF+++++++K     +++ K+  W+ F + F+ LPK+++D+              RNGFY IF  +  +I
Sbjct:   60 IIEKSPNLRFHKRNKKYMRKVPGIDNSFIAIEPKSGKEVIWNEINLSDKKTEQENRFINLIKKLKRYNHPFFVRFLDVWQSKPESGFRKVIFVTERLTDPTMKQYFVNSSSSHRLTNKSLWRKFVGQLISVLKFLNHLGVHHGNLSNETVYYQNTGCLKVGTLSVDLSFDNKPSSDIYDMGKLALEMAAYEALDDTESLSTKDRIQKMLSRVTDSAQGSFIQICLDNAENPTTLSKLFQHIVL-KEVPSLKRLAAKIIVKNSISTSEDDKLENQHSM---FTTIFKEQVGHFEDETILIKVVFPHDNITKMRLWKEFRINFSNLPKYIEDV--------------RNGFYPIFEAKSGQI 401
The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NRBP16.333e-1531.29nuclear receptor binding protein 1 [Source:HGNC Sy... [more]
NRBP16.333e-1531.29nuclear receptor binding protein 1 [Source:HGNC Sy... [more]
NRBP12.025e-1430.72nuclear receptor binding protein 1 [Source:HGNC Sy... [more]
NRBP23.240e-1429.21nuclear receptor binding protein 2 [Source:HGNC Sy... [more]
NRBP21.570e-1228.57nuclear receptor binding protein 2 [Source:HGNC Sy... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hpo-115.162e-1230.86pep chromosome:WBcel235:I:7140278:7147230:-1 gene:... [more]
wnk-19.176e-929.49Serine/threonine-protein kinase WNK [Source:UniPr... [more]
wnk-19.247e-929.49Serine/threonine-protein kinase WNK [Source:UniPr... [more]
wnk-19.257e-929.49Serine/threonine-protein kinase WNK [Source:UniPr... [more]
wnk-19.293e-929.49Serine/threonine-protein kinase WNK [Source:UniPr... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Madm5.193e-1325.40gene:FBgn0027497 transcript:FBtr0347493[more]
Madm5.193e-1325.40gene:FBgn0027497 transcript:FBtr0078722[more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nrbp2b1.223e-1631.69nuclear receptor binding protein 2b [Source:ZFIN;A... [more]
nrbp2a2.715e-1628.91nuclear receptor binding protein 2a [Source:ZFIN;A... [more]
nrbp2a4.463e-1525.97nuclear receptor binding protein 2a [Source:ZFIN;A... [more]
nrbp11.256e-1427.89nuclear receptor binding protein 1 [Source:ZFIN;Ac... [more]
nrbp11.419e-1427.89nuclear receptor binding protein 1 [Source:ZFIN;Ac... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nrbp16.347e-1530.67nuclear receptor binding protein 1 [Source:MGI Sym... [more]
Nrbp27.208e-1524.66nuclear receptor binding protein 2 [Source:MGI Sym... [more]
Nrbp11.717e-1430.12nuclear receptor binding protein 1 [Source:MGI Sym... [more]
Nrbp14.396e-1229.17nuclear receptor binding protein 1 [Source:MGI Sym... [more]
Nrbp21.006e-726.61nuclear receptor binding protein 2 [Source:MGI Sym... [more]
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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q4R8X0|NRBP_MACFA3.042e-1431.29Nuclear receptor-binding protein OS=Macaca fascicu... [more]
sp|Q9UHY1|NRBP_HUMAN3.042e-1431.29Nuclear receptor-binding protein OS=Homo sapiens O... [more]
sp|Q5RBH9|NRBP_PONAB3.440e-1431.29Nuclear receptor-binding protein OS=Pongo abelii O... [more]
sp|Q99J45|NRBP_MOUSE4.440e-1430.67Nuclear receptor-binding protein OS=Mus musculus O... [more]
sp|Q91V36|NRBP2_MOUSE5.042e-1424.66Nuclear receptor-binding protein 2 OS=Mus musculus... [more]
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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P7PV619.185e-4031.36Protein kinase domain-containing protein OS=Diboth... [more]
A0A3R7CYA61.454e-3830.85Nuclear receptor-binding protein OS=Clonorchis sin... [more]
A0A4V3SD123.517e-3830.85Protein kinase domain-containing protein OS=Opisth... [more]
A0A2H1C0482.952e-3729.45Protein kinase domain-containing protein OS=Fascio... [more]
A0A4Z2DBA64.882e-3629.33Nuclear receptor-binding protein OS=Schistosoma ja... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nrbp2a1.447e-1732.16nuclear receptor binding protein 2a [Source:ZFIN;A... [more]
nrbp13.328e-1431.14nuclear receptor binding protein 1 [Source:NCBI ge... [more]
nrbp13.541e-1431.14nuclear receptor binding protein 1 [Source:NCBI ge... [more]
wnk4b5.438e-626.62serine/threonine-protein kinase WNK4-like [Source:... [more]
ENSAMXT00000041214.19.024e-627.34serine/threonine-protein kinase WNK1 [Source:NCBI ... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
nrbp11.209e-1632.93nuclear receptor binding protein 1 [Source:ZFIN;Ac... [more]
nrbp15.522e-1530.12nuclear receptor binding protein 1 [Source:ZFIN;Ac... [more]
nrbp17.101e-1530.12nuclear receptor binding protein 1 [Source:ZFIN;Ac... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO361102.475e-1627.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nrbp2b4.990e-1730.50nuclear receptor binding protein 2 [Source:NCBI ge... [more]
ENSORLT00000014317.22.236e-1529.05nuclear receptor-binding protein [Source:NCBI gene... [more]
nrbp11.456e-1429.24nuclear receptor-binding protein [Source:NCBI gene... [more]
nrbp11.629e-1431.14nuclear receptor-binding protein [Source:NCBI gene... [more]
nrbp12.154e-1431.14nuclear receptor-binding protein [Source:NCBI gene... [more]
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BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000065913.10.000e+094.36SMESG000065913.1[more]
SMESG000066284.19.494e-6336.94SMESG000066284.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032932 ID=SMED30032932|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1733bp
TCAAATTTGTATTTTTAAAAAATATTCCGTTTATAATCTACTTTAGATTT
TTATTCTGAAAAATTATAAATGAAAGAGTTAATACACAACAAGCCAGTTG
AAGTAAAATCAATAGATGAAACATCTAATGATATTTTCAAGATATTAAGT
AATATATCAAACGAAAATGAAGCTAATAGTGAAGAAAACGAATATTTAAT
TATTGAGAAAAGTCCCAGTTTAGAATTTCATAAAAGAAATAGAATATATT
TTCAGAACGTCAAGTATATCGATTCAAGTTCACTGGCAATTGAACCAAAA
ACCGGTAAACAAGTCATTTGGAATGAAATTTACTTGAATAAAGTGGATAT
TGAAAAAAAAAATTTTTTGGAAATTATAAGTCGCTTGCGACAATTTAATC
ATCCATTTATTTTAAAGTTTTATGAATCTTGGATTTCAATAAATGAAAAC
GGTGAAAGGAAAATTAATTTTATAACGGAACGCATAACAATTCCAACTTT
TAGAGAGTATATAACTCATACGAAATTGTCTCAAAGACTAAATGATAAAA
CTTCTTGGAAAAAAATGACAGGTCAATTGTTATCTGCCATGACATTTCTT
CGGGATATTGGTATAGCGAATAGTGAGATAACCAATGAAAATATCCACCA
ATCAAATTGTACTATTAAAATCGGATTGGGCGCTATTGATTTGTTTTCTA
ATGGAAATCCATCGAAATCATTTTCTGATTTTGGAAAATTGATTCTAGAA
ATGTGTGCATATCATCATCACCTGGATATTCAGAGCAATTTACAATCAAA
TGATATTGATACAATGCTTGAGAGGGTAATTTTTAACGATCAAAAAGATT
TCATTGTTAGTTCAATGACTGAGAATCGTTTTTCGAATCTATTGAATAAT
TTCCACGTGAAATTGCAAAAGCTTGTTATCAGCCTCAAAGTGTTAGCTGG
GAAAAAATTAGTTGACAATATTTCTCATACGAACACCTTTGCAATTAAAG
AGAACTGTAGATCAATTTATTCTCCATTTGATGATTTACTGGGATCACAC
ATTGATCATTTTGACAACGATTCCGTCATTGTAAAATGTAGGAAAAATTC
TTTGGAAAAACTTTTAAAATGGGAAAATTTTCTGTTGGCCTTTACAATTC
TGCCAAAATTTCTCGATGACATTCGGTAAGTTAATTTCTAAAATCGTTTA
AAAGTTATGTGAAATAGAAATGGGTTTTATAGTATTTTTACAAACGAATA
TTGCGAAATAGTTTCGAATTCTCTAGAATTAAATTCAGGTTTGAAAATCT
GGGAGAAAATGAAAACTATATTTTTGATTTCTTTTTAGATGTTATCAATC
TAGGAAATGATTTTCGTGTATCATCAGACAATCTCATTGATTTCGATTCG
ACATTATTGGAAAACGAAGAACTAATCAAGAACTTAGAAGTGAAAGAAAA
GATCTTTATTATTCATGAAGACTCTTCCAGTAGAGAATCGGAAATCAAAA
GTGAACAAGTTCAAAATTTGCTTAATTTAAGCGTTGATGGAGAAACAAAT
CTGATAGATTTCCGAAGTCCAGTTTTGGAGAAAAAATCTCTGATTAATAT
TCCCGTTGATGAGAGTTCGGTGAATGAAACGATGTTCCAGAATCTGGATA
ACTTATTTGATAAGGAAATCATAAAATGCAGGCCCCATGATATGCGGATT
AAAATTGAAAGTCCATTGGATACAATACCTCAC
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protein sequence of SMED30032932-orf-1

>SMED30032932-orf-1 ID=SMED30032932-orf-1|Name=SMED30032932-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=370bp
MKELIHNKPVEVKSIDETSNDIFKILSNISNENEANSEENEYLIIEKSPS
LEFHKRNRIYFQNVKYIDSSSLAIEPKTGKQVIWNEIYLNKVDIEKKNFL
EIISRLRQFNHPFILKFYESWISINENGERKINFITERITIPTFREYITH
TKLSQRLNDKTSWKKMTGQLLSAMTFLRDIGIANSEITNENIHQSNCTIK
IGLGAIDLFSNGNPSKSFSDFGKLILEMCAYHHHLDIQSNLQSNDIDTML
ERVIFNDQKDFIVSSMTENRFSNLLNNFHVKLQKLVISLKVLAGKKLVDN
ISHTNTFAIKENCRSIYSPFDDLLGSHIDHFDNDSVIVKCRKNSLEKLLK
WENFLLAFTILPKFLDDIR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000026gut
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 95..203
e-value: 7.9E-11
score: 43.7
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 72..139
e-value: 7.9E-11
score: 43.7
NoneNo IPR availablePANTHERPTHR13902:SF67NUCLEAR RECEPTOR-BINDING PROTEIN HOMOLOGcoord: 29..205
NoneNo IPR availablePANTHERPTHR13902SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATEDcoord: 29..205
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 73..202