Protein Jade-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032893 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Protein Jade-1 vs. Ensembl Human
Match: JADE1 (jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]) HSP 1 Score: 285.419 bits (729), Expect = 4.421e-83 Identity = 180/516 (34.88%), Postives = 273/516 (52.91%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 542
BLAST of Protein Jade-1 vs. Ensembl Human
Match: JADE1 (jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]) HSP 1 Score: 285.419 bits (729), Expect = 4.421e-83 Identity = 180/516 (34.88%), Postives = 273/516 (52.91%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 542
BLAST of Protein Jade-1 vs. Ensembl Human
Match: JADE1 (jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]) HSP 1 Score: 285.419 bits (729), Expect = 4.421e-83 Identity = 180/516 (34.88%), Postives = 273/516 (52.91%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 542
BLAST of Protein Jade-1 vs. Ensembl Human
Match: JADE1 (jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]) HSP 1 Score: 285.419 bits (729), Expect = 4.421e-83 Identity = 180/516 (34.88%), Postives = 273/516 (52.91%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 542
BLAST of Protein Jade-1 vs. Ensembl Human
Match: JADE1 (jade family PHD finger 1 [Source:HGNC Symbol;Acc:HGNC:30027]) HSP 1 Score: 282.722 bits (722), Expect = 3.050e-82 Identity = 181/512 (35.35%), Postives = 272/512 (53.12%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIM------PEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + +I+ PE R L + C Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARPKKYIVSSGSEPPELGYVDIRT---LADSVCR--------YDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 530
BLAST of Protein Jade-1 vs. Ensembl Celegans
Match: lin-49 (pep chromosome:WBcel235:IV:8620683:8626149:1 gene:WBGene00003034.1 transcript:F42A9.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-49) HSP 1 Score: 163.696 bits (413), Expect = 3.867e-41 Identity = 85/238 (35.71%), Postives = 128/238 (53.78%), Query Frame = 3
Query: 444 YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQS--KVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCK---TSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS 1142
Y +D D SW+ I N +R LGL++ S + E + LE++C + + K+++ E L+ C++C + + N++V+C+ C + VHQ CYGIP +P G CR C P C+LCP+ GA KQ+ D+ +W H+ C +W+ E FGN ME + + R L C LCK + GA IQCSE KC +FHVTCA + LVM+ + V +C +H+
Sbjct: 135 YSVDEFDMSWMSIMNAKRTKLGLEIFSVAIYEHWVDRLEKMCIWKPKEFHKLKDENGEELD----DVCNICLDGDTSNCNQIVYCDRCNLSVHQDCYGIPFIPEGCLECRRCGISPAGRVNCVLCPSTTGAFKQV--DQKRWVHVLCVIWVDETHFGNTIFMENVQNVEKALHDRRALSCLLCKNRQNARMGACIQCSETKCTASFHVTCARDSGLVMRINETEDGQVNRFVWCPKHA 366
BLAST of Protein Jade-1 vs. Ensembl Celegans
Match: phf-15 (PHd Finger family [Source:UniProtKB/TrEMBL;Acc:Q9N3F6]) HSP 1 Score: 135.191 bits (339), Expect = 1.624e-32 Identity = 94/319 (29.47%), Postives = 158/319 (49.53%), Query Frame = 3
Query: 225 IITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTR-KYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCL--GLQLISETMLEIIFEILERLCYKRIQSKVREAETEFL-----EHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGS--WICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQAN---MDVKLLAYCKQHS 1142
+I+D+W P++ G + +E ++ + + F P+K I R +F H + YEI D ++++ N+ERK L L T + II E LE +K+I + + ++ + E+++CDVC+ + + +E+VFC+ C CVH C GI ELP + W C C C+LCP GG+M +D+ +WAH SCA++IPE+ F N +L P+T + + RW+ C +C T GA + CS C+ +HV CA++ + ++ + N +V + YC +H+
Sbjct: 97 MISDNWKPEY--SGGTQELAHPDELPQTIVNDDDFWLKPKDFFSTPKKRIVCNRNSVDFDENIHEEVTTRDALHYEITAHDMAFLQKINMERKLLTGDTYLPMATFIRIIKE-LETEAFKQIHNHLLDSLHVVYCRPPEDGGEDAECDVCRISDCDVADEMVFCDMCNTCVHMVCAGIEELPDPAEPWKCAKCAHMGTPCPPCVLCPALGGSMT-YSADKTQWAHHSCALFIPEIIFENEELRAPMTSFERVAEERWSQMCSVCDTRQ-GACVTCSWVDCEETYHVCCALRAGMTVRIQEVPNDPEHNVTRVTYCHKHT 410
BLAST of Protein Jade-1 vs. Ensembl Celegans
Match: phf-15 (PHd Finger family [Source:UniProtKB/TrEMBL;Acc:Q9N3F6]) HSP 1 Score: 135.191 bits (339), Expect = 1.862e-32 Identity = 94/319 (29.47%), Postives = 158/319 (49.53%), Query Frame = 3
Query: 225 IITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTR-KYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCL--GLQLISETMLEIIFEILERLCYKRIQSKVREAETEFL-----EHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGS--WICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQAN---MDVKLLAYCKQHS 1142
+I+D+W P++ G + +E ++ + + F P+K I R +F H + YEI D ++++ N+ERK L L T + II E LE +K+I + + ++ + E+++CDVC+ + + +E+VFC+ C CVH C GI ELP + W C C C+LCP GG+M +D+ +WAH SCA++IPE+ F N +L P+T + + RW+ C +C T GA + CS C+ +HV CA++ + ++ + N +V + YC +H+
Sbjct: 138 MISDNWKPEY--SGGTQELAHPDELPQTIVNDDDFWLKPKDFFSTPKKRIVCNRNSVDFDENIHEEVTTRDALHYEITAHDMAFLQKINMERKLLTGDTYLPMATFIRIIKE-LETEAFKQIHNHLLDSLHVVYCRPPEDGGEDAECDVCRISDCDVADEMVFCDMCNTCVHMVCAGIEELPDPAEPWKCAKCAHMGTPCPPCVLCPALGGSM-TYSADKTQWAHHSCALFIPEIIFENEELRAPMTSFERVAEERWSQMCSVCDTRQ-GACVTCSWVDCEETYHVCCALRAGMTVRIQEVPNDPEHNVTRVTYCHKHT 451
BLAST of Protein Jade-1 vs. Ensembl Celegans
Match: zfp-1 (Uncharacterized protein F54F2.2, isoform a [Source:UniProtKB/Swiss-Prot;Acc:P34447]) HSP 1 Score: 133.65 bits (335), Expect = 7.505e-32 Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFC--EDCFVCVHQACYGIPELPSGSWICRHCDKCP-------NESSQCI-LCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLC-----KTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKK 1148
C VC G N L++C E+C V VHQ CYGI E+P G W C C K NE++ C LCP GA+K+ +D + WAH+ CA++IPEV FGN+ MEP+ LN +P ++N C++C + GA + C++ CK +FHVTCA + L+ +E + +VK YC+ H KK
Sbjct: 8 CCVCADENGWTDNPLIYCDGENCEVAVHQGCYGIQEVPEGEWFCAKCTKASAMMPGSINEATFCCQLCPFDYGALKK--TDRNGWAHVICALYIPEVRFGNVHSMEPVI-LNDVPTDKFNKLCYICNEERPNDAKKGACMSCNKSTCKRSFHVTCAQRKGLLC-EEGAISRNVKYCGYCENHLKK 188
BLAST of Protein Jade-1 vs. Ensembl Celegans
Match: zfp-1 (Uncharacterized protein F54F2.2, isoform a [Source:UniProtKB/Swiss-Prot;Acc:P34447]) HSP 1 Score: 133.65 bits (335), Expect = 7.505e-32 Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFC--EDCFVCVHQACYGIPELPSGSWICRHCDKCP-------NESSQCI-LCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLC-----KTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKK 1148
C VC G N L++C E+C V VHQ CYGI E+P G W C C K NE++ C LCP GA+K+ +D + WAH+ CA++IPEV FGN+ MEP+ LN +P ++N C++C + GA + C++ CK +FHVTCA + L+ +E + +VK YC+ H KK
Sbjct: 8 CCVCADENGWTDNPLIYCDGENCEVAVHQGCYGIQEVPEGEWFCAKCTKASAMMPGSINEATFCCQLCPFDYGALKK--TDRNGWAHVICALYIPEVRFGNVHSMEPVI-LNDVPTDKFNKLCYICNEERPNDAKKGACMSCNKSTCKRSFHVTCAQRKGLLC-EEGAISRNVKYCGYCENHLKK 188
BLAST of Protein Jade-1 vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0305549) HSP 1 Score: 263.462 bits (672), Expect = 2.905e-73 Identity = 147/348 (42.24%), Postives = 217/348 (62.36%), Query Frame = 3
Query: 138 SKDSHAEVFDKHPITAMS--EVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSE--IKHIGKPA-AKTENFIMPE-KLIRHTRKYEFLPEKH--CHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK---QEFQANMDVKLLAYCKQHS 1142
S ++ AE++ K I+AM + +P + LI+TD W +W + GVQVPV N E + + +P + +F +P+ + +R T+ + P+ H ++ + E Y+IDPID +W+ + N +R G I+ T E + E LE C+++IQ ++ E +E DEN CDVC+SP+ E+ NE+VFC++C +CVHQACYGI +PSG W+CR C C+LCPN+GGAMK +S + WAH+SCA+WIPEV G +D MEPIT++++IPQ+RW+L C LC+ G+ IQCS K CK A+HVTCA Q+ L M+ +E A VKL +YC++HS
Sbjct: 142 STEAPAELYRKDLISAMKLPDSEPLANYEYLIVTDPWKQEWEK-GVQVPV---NPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTCSM--GIKPDCVLCPNKGGAMKSNKSGK-HWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAEDGVKLRSYCQKHS 481
BLAST of Protein Jade-1 vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0305548) HSP 1 Score: 263.462 bits (672), Expect = 2.905e-73 Identity = 147/348 (42.24%), Postives = 217/348 (62.36%), Query Frame = 3
Query: 138 SKDSHAEVFDKHPITAMS--EVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSE--IKHIGKPA-AKTENFIMPE-KLIRHTRKYEFLPEKH--CHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK---QEFQANMDVKLLAYCKQHS 1142
S ++ AE++ K I+AM + +P + LI+TD W +W + GVQVPV N E + + +P + +F +P+ + +R T+ + P+ H ++ + E Y+IDPID +W+ + N +R G I+ T E + E LE C+++IQ ++ E +E DEN CDVC+SP+ E+ NE+VFC++C +CVHQACYGI +PSG W+CR C C+LCPN+GGAMK +S + WAH+SCA+WIPEV G +D MEPIT++++IPQ+RW+L C LC+ G+ IQCS K CK A+HVTCA Q+ L M+ +E A VKL +YC++HS
Sbjct: 142 STEAPAELYRKDLISAMKLPDSEPLANYEYLIVTDPWKQEWEK-GVQVPV---NPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTCSM--GIKPDCVLCPNKGGAMKSNKSGK-HWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAEDGVKLRSYCQKHS 481
BLAST of Protein Jade-1 vs. Ensembl Fly
Match: rno (gene:FBgn0035106 transcript:FBtr0072532) HSP 1 Score: 263.462 bits (672), Expect = 2.905e-73 Identity = 147/348 (42.24%), Postives = 217/348 (62.36%), Query Frame = 3
Query: 138 SKDSHAEVFDKHPITAMS--EVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSE--IKHIGKPA-AKTENFIMPE-KLIRHTRKYEFLPEKH--CHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK---QEFQANMDVKLLAYCKQHS 1142
S ++ AE++ K I+AM + +P + LI+TD W +W + GVQVPV N E + + +P + +F +P+ + +R T+ + P+ H ++ + E Y+IDPID +W+ + N +R G I+ T E + E LE C+++IQ ++ E +E DEN CDVC+SP+ E+ NE+VFC++C +CVHQACYGI +PSG W+CR C C+LCPN+GGAMK +S + WAH+SCA+WIPEV G +D MEPIT++++IPQ+RW+L C LC+ G+ IQCS K CK A+HVTCA Q+ L M+ +E A VKL +YC++HS
Sbjct: 142 STEAPAELYRKDLISAMKLPDSEPLANYEYLIVTDPWKQEWEK-GVQVPV---NPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTCSM--GIKPDCVLCPNKGGAMKSNKSGK-HWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSVKPCKTAYHVTCAFQHGLEMRAIIEEGNAEDGVKLRSYCQKHS 481
BLAST of Protein Jade-1 vs. Ensembl Fly
Match: Br140 (gene:FBgn0033155 transcript:FBtr0089021) HSP 1 Score: 221.476 bits (563), Expect = 1.410e-59 Identity = 135/421 (32.07%), Postives = 218/421 (51.78%), Query Frame = 3
Query: 435 EFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEF------QANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLKSIPS-----DIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI------------MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
E Y++D DS+W+E N ER+ LGL + +E++ + LE+ + Q+ T +E D+++ C +C E ++ N ++FC+ C + VHQ CYG+P +P G W+CR C + P++ C+LCPN GGA KQ +D +WAH+ CA+WIPEV F N +EPI + TIP ARW L C++CK GA IQC C AFHVTCA Q L M + ++M V+ AYC H+ +++ + M D ++ R + ++ + K A + + P + + ++ + + D+I YWTLKR + L++ + S+ N I I + + +R L+RARL+ +++ +REK K + ++ LQL L+ + LN +L
Sbjct: 221 EVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKESH--FQAAANGTPT-GVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQ--TDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHT-------PADAKLKMNVPDFEDTRHKMKEARKALAKKRSTAPVV--LIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLR--RLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAA-LNKLL 624
BLAST of Protein Jade-1 vs. Ensembl Fly
Match: Br140 (gene:FBgn0033155 transcript:FBtr0345370) HSP 1 Score: 221.476 bits (563), Expect = 1.410e-59 Identity = 135/421 (32.07%), Postives = 218/421 (51.78%), Query Frame = 3
Query: 435 EFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEF------QANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLKSIPS-----DIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI------------MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
E Y++D DS+W+E N ER+ LGL + +E++ + LE+ + Q+ T +E D+++ C +C E ++ N ++FC+ C + VHQ CYG+P +P G W+CR C + P++ C+LCPN GGA KQ +D +WAH+ CA+WIPEV F N +EPI + TIP ARW L C++CK GA IQC C AFHVTCA Q L M + ++M V+ AYC H+ +++ + M D ++ R + ++ + K A + + P + + ++ + + D+I YWTLKR + L++ + S+ N I I + + +R L+RARL+ +++ +REK K + ++ LQL L+ + LN +L
Sbjct: 221 EVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKESH--FQAAANGTPT-GVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQ--TDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHT-------PADAKLKMNVPDFEDTRHKMKEARKALAKKRSTAPVV--LIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLR--RLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAA-LNKLL 624
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Match: jade2 (jade family PHD finger 2 [Source:ZFIN;Acc:ZDB-GENE-120215-66]) HSP 1 Score: 275.018 bits (702), Expect = 1.850e-82 Identity = 181/502 (36.06%), Postives = 270/502 (53.78%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQ---LIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEE--NLKQRINN--RSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNS 1610
+EVF ITAM D S D I+ D W +W GVQVP + ++ I +P + ++PE +R F + E+ E L Y++D +D +W+E+ N E + L L + E +E + LER C + +Q ++ E +E+DE+ CDVC+SPEGEDGNE+VFC++C VCVHQACYGI ++P G+W+CR C S+C+LCP RGGA+K S KW H+SCA+WIPEV G + MEPIT+++ IP +RW L C LC ++G IQCS C +AFHVTCA + L M+ N +V+ +YC +HS ++ + S V D + +Q+ ++ A + + L E + L+DP S+P D +F YW L+R +N + L+ S+ +E NL Q+ + + F +R L+R R + M+ RREK K L L KI SLQ++ ++ +
Sbjct: 49 SEVFRTDFITAMKLPDSAQLSADEFYILCDPWRQEW-EKGVQVP---------ANVETIPEPVVR----MLPEV----SRIPFFSAVQTRSQSEISEPLSRYDLDDLDVAWLELVNAEFRQLALPELDELTMEQLLVELERRCQQNMQQQIENQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDNCNVCVHQACYGILKVPQGNWLCRTC--ALGVQSKCLLCPRRGGALKPTRSG-TKWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLC-CEHSGTCIQCSMPSCTVAFHVTCAFDHGLEMRTTLADNDEVRFKSYCLEHSSVWR--SNSSGGVQSDRPDPRHAVPDPAAAQKQEQAEREKASQRKQKLQELEDEFYTLVDPKDIAESLSLPDAHVDFLFQYWKLRRKTNGNKPLV---SMKRDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCCMITRREKIKHSLCNLQEKIFSLQIQLMEQN 523
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Match: jade2 (jade family PHD finger 2 [Source:ZFIN;Acc:ZDB-GENE-120215-66]) HSP 1 Score: 277.33 bits (708), Expect = 1.126e-80 Identity = 194/561 (34.58%), Postives = 286/561 (50.98%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQ---LIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEE--NLKQRINN--RSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQL------------------------EQLKNSRLNSILK------DDPSLAGNWGFISTVHLDDNVY 1697
+EVF ITAM D S D I+ D W +W GVQVP + ++ I +P + ++PE +R F + E+ E L Y++D +D +W+E+ N E + L L + E +E + LER C + +Q ++ E +E+DE+ CDVC+SPEGEDGNE+VFC++C VCVHQACYGI ++P G+W+CR C S+C+LCP RGGA+K S KW H+SCA+WIPEV G + MEPIT+++ IP +RW L C LC ++G IQCS C +AFHVTCA + L M+ N +V+ +YC +HS ++ + S V D + +Q+ ++ A + + L E + L+DP S+P D +F YW L+R +N + L+ S+ +E NL Q+ + + F +R L+R R + M+ RREK K L L KI SLQ+ E++K R NS K DD SL GF + +D +++
Sbjct: 49 SEVFRTDFITAMKLPDSAQLSADEFYILCDPWRQEW-EKGVQVP---------ANVETIPEPVVR----MLPEV----SRIPFFSAVQTRSQSEISEPLSRYDLDDLDVAWLELVNAEFRQLALPELDELTMEQLLVELERRCQQNMQQQIENQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDNCNVCVHQACYGILKVPQGNWLCRTC--ALGVQSKCLLCPRRGGALKPTRSG-TKWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLC-CEHSGTCIQCSMPSCTVAFHVTCAFDHGLEMRTTLADNDEVRFKSYCLEHSSVWR--SNSSGGVQSDRPDPRHAVPDPAAAQKQEQAEREKASQRKQKLQELEDEFYTLVDPKDIAESLSLPDAHVDFLFQYWKLRRKTNGNKPLV---SMKRDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCCMITRREKIKHSLCNLQEKIFSLQIQLMEQNLVGEKSQRGERKHRNRVQERVKERRKNSPEKKDKWRSDDNSLFSQLGFSRSFPIDGSLF 582
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Match: jade3 (jade family PHD finger 3 [Source:NCBI gene;Acc:322209]) HSP 1 Score: 273.863 bits (699), Expect = 1.850e-79 Identity = 184/511 (36.01%), Postives = 273/511 (53.42%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKY------EFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF-----PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
AEVF K I+AM D + S++ ++ D+W +W GVQV I +P+ + E L RKY + + ++ E+ E + Y++D +D W++ N E +G ++ E +E + E LER C++ + + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C + QC+LCP GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK +YC +HSK K EP S + + P + +L + A++L E EF P+++ L S+P + D IF YW +KR SN + L+ P EENL + SI M F +R L+R R + M+ RREK K + +I +L + +L N L++ L
Sbjct: 42 AEVFRKDLISAMKLPDSHHISSEDYYLLADTWKQEW-EKGVQVLASPDT---------IPQPSVRIITEKPKEVLFSKPRKYIQCWSQDSTETGYVNIKELAEAMCRYDLDDMDLYWLQQLNAELGMMGDGVVDELTMERVMEALERQCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNWLCRTC--VLGITPQCLLCPKTGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKVSHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSYCLKHSKPKAGEPGLSPAR-HKPPTETDKLSL--------------RAQKLQELEEEFYTYVHPEEVAHDL-SLPLHLLDFIFQYWKMKRKSNFNKALLPPKE--DEENLLLQPQEDSIHTRMRMFMHLRQDLERVRNLCYMVSRREKLKLSQSKAQEQIFNLHV-KLVNQELSAGL 519
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Match: jade3 (jade family PHD finger 3 [Source:NCBI gene;Acc:322209]) HSP 1 Score: 273.863 bits (699), Expect = 1.850e-79 Identity = 184/511 (36.01%), Postives = 273/511 (53.42%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKY------EFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF-----PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
AEVF K I+AM D + S++ ++ D+W +W GVQV I +P+ + E L RKY + + ++ E+ E + Y++D +D W++ N E +G ++ E +E + E LER C++ + + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C + QC+LCP GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK +YC +HSK K EP S + + P + +L + A++L E EF P+++ L S+P + D IF YW +KR SN + L+ P EENL + SI M F +R L+R R + M+ RREK K + +I +L + +L N L++ L
Sbjct: 42 AEVFRKDLISAMKLPDSHHISSEDYYLLADTWKQEW-EKGVQVLASPDT---------IPQPSVRIITEKPKEVLFSKPRKYIQCWSQDSTETGYVNIKELAEAMCRYDLDDMDLYWLQQLNAELGMMGDGVVDELTMERVMEALERQCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNWLCRTC--VLGITPQCLLCPKTGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKVSHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSYCLKHSKPKAGEPGLSPAR-HKPPTETDKLSL--------------RAQKLQELEEEFYTYVHPEEVAHDL-SLPLHLLDFIFQYWKMKRKSNFNKALLPPKE--DEENLLLQPQEDSIHTRMRMFMHLRQDLERVRNLCYMVSRREKLKLSQSKAQEQIFNLHV-KLVNQELSAGL 519
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Match: jade2 (jade family PHD finger 2 [Source:ZFIN;Acc:ZDB-GENE-120215-66]) HSP 1 Score: 271.552 bits (693), Expect = 4.742e-79 Identity = 186/541 (34.38%), Postives = 277/541 (51.20%), Query Frame = 3
Query: 207 STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQ---LIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEE--NLKQRINN--RSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQL------------------------EQLKNSRLNSILK------DDPSLAGNWGFISTVHLDDNVY 1697
S D I+ D W +W GVQVP + ++ I +P + ++PE +R F + E+ E L Y++D +D +W+E+ N E + L L + E +E + LER C + +Q ++ E +E+DE+ CDVC+SPEGEDGNE+VFC++C VCVHQACYGI ++P G+W+CR C S+C+LCP RGGA+K S KW H+SCA+WIPEV G + MEPIT+++ IP +RW L C LC ++G IQCS C +AFHVTCA + L M+ N +V+ +YC +HS ++ + S V D + +Q+ ++ A + + L E + L+DP S+P D +F YW L+R +N + L+ S+ +E NL Q+ + + F +R L+R R + M+ RREK K L L KI SLQ+ E++K R NS K DD SL GF + +D +++
Sbjct: 10 SADEFYILCDPWRQEW-EKGVQVP---------ANVETIPEPVVR----MLPEV----SRIPFFSAVQTRSQSEISEPLSRYDLDDLDVAWLELVNAEFRQLALPELDELTMEQLLVELERRCQQNMQQQIENQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDNCNVCVHQACYGILKVPQGNWLCRTC--ALGVQSKCLLCPRRGGALKPTRSG-TKWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLC-CEHSGTCIQCSMPSCTVAFHVTCAFDHGLEMRTTLADNDEVRFKSYCLEHSSVWR--SNSSGGVQSDRPDPRHAVPDPAAAQKQEQAEREKASQRKQKLQELEDEFYTLVDPKDIAESLSLPDAHVDFLFQYWKLRRKTNGNKPLV---SMKRDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCCMITRREKIKHSLCNLQEKIFSLQIQLMEQNLVGEKSQRGERKHRNRVQERVKERRKNSPEKKDKWRSDDNSLFSQLGFSRSFPIDGSLF 523
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Match: cfp (complement factor properdin [Source:Xenbase;Acc:XB-GENE-5941221]) HSP 1 Score: 281.567 bits (719), Expect = 2.455e-82 Identity = 183/518 (35.33%), Postives = 262/518 (50.58%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAK--ELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKISSLQLEQLKN 1607
+EVF ITAM D N D ++ D W +W GVQVPV P +K++ TR +++ PE+ Y++D +D +W+E+ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H + N+ + + P + LR+ + + K K +L + H F Q I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS EQ KN
Sbjct: 29 SEVFRTDLITAMKLHDSYQLNPED-FYVLADPWRQEW-EKGVQVPVNPEF-----------IPETVAREIAEKDKVVTFTRPRKYIRSSGSEPPELGYVDIQTLADAVCRYDLDEMDVAWLELINEEFKEMGMQQLDEYSMERVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALFCSLC-NEKLGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTEEDEVKFKSYCPKHGSTKKPENSHFCKSVNDGKGTCGASPTCLDGLRLLDVSQQDAKHGSQRKFKLQQLEDEFHTFVDVQEISQALKIPLDMTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYAKIS----EQEKN 524
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Match: cfp (complement factor properdin [Source:Xenbase;Acc:XB-GENE-5941221]) HSP 1 Score: 281.567 bits (719), Expect = 3.080e-82 Identity = 184/518 (35.52%), Postives = 264/518 (50.97%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAK--ELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKISSLQLEQLKN 1607
+EVF ITAM D N D ++ D W +W GVQVPV + I P +K++ TR +++ PE+ Y++D +D +W+E+ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H + N+ + + P + LR+ + + K K +L + H F Q I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS EQ KN
Sbjct: 43 SEVFRTDLITAMKLHDSYQLNPED-FYVLADPWRQEW-EKGVQVPVNP---------EFI--PETVAREIAEKDKVVTFTRPRKYIRSSGSEPPELGYVDIQTLADAVCRYDLDEMDVAWLELINEEFKEMGMQQLDEYSMERVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALFCSLC-NEKLGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTEEDEVKFKSYCPKHGSTKKPENSHFCKSVNDGKGTCGASPTCLDGLRLLDVSQQDAKHGSQRKFKLQQLEDEFHTFVDVQEISQALKIPLDMTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYAKIS----EQEKN 538
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Match: cfp (complement factor properdin [Source:Xenbase;Acc:XB-GENE-5941221]) HSP 1 Score: 281.952 bits (720), Expect = 6.177e-82 Identity = 184/518 (35.52%), Postives = 264/518 (50.97%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAK--ELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKISSLQLEQLKN 1607
+EVF ITAM D N D ++ D W +W GVQVPV + I P +K++ TR +++ PE+ Y++D +D +W+E+ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H + N+ + + P + LR+ + + K K +L + H F Q I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS EQ KN
Sbjct: 40 SEVFRTDLITAMKLHDSYQLNPED-FYVLADPWRQEW-EKGVQVPVNP---------EFI--PETVAREIAEKDKVVTFTRPRKYIRSSGSEPPELGYVDIQTLADAVCRYDLDEMDVAWLELINEEFKEMGMQQLDEYSMERVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALFCSLC-NEKLGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTEEDEVKFKSYCPKHGSTKKPENSHFCKSVNDGKGTCGASPTCLDGLRLLDVSQQDAKHGSQRKFKLQQLEDEFHTFVDVQEISQALKIPLDMTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYAKIS----EQEKN 535
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Match: cfp (complement factor properdin [Source:Xenbase;Acc:XB-GENE-5941221]) HSP 1 Score: 281.952 bits (720), Expect = 6.580e-82 Identity = 184/518 (35.52%), Postives = 264/518 (50.97%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAK--ELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKISSLQLEQLKN 1607
+EVF ITAM D N D ++ D W +W GVQVPV + I P +K++ TR +++ PE+ Y++D +D +W+E+ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H + N+ + + P + LR+ + + K K +L + H F Q I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS EQ KN
Sbjct: 43 SEVFRTDLITAMKLHDSYQLNPED-FYVLADPWRQEW-EKGVQVPVNP---------EFI--PETVAREIAEKDKVVTFTRPRKYIRSSGSEPPELGYVDIQTLADAVCRYDLDEMDVAWLELINEEFKEMGMQQLDEYSMERVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALFCSLC-NEKLGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTEEDEVKFKSYCPKHGSTKKPENSHFCKSVNDGKGTCGASPTCLDGLRLLDVSQQDAKHGSQRKFKLQQLEDEFHTFVDVQEISQALKIPLDMTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYAKIS----EQEKN 538
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Match: cfp (complement factor properdin [Source:Xenbase;Acc:XB-GENE-5941221]) HSP 1 Score: 280.411 bits (716), Expect = 1.969e-81 Identity = 184/520 (35.38%), Postives = 264/520 (50.77%), Query Frame = 3
Query: 147 SHAEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAK--ELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKISSLQLEQLKN 1607
S + VF ITAM D N D ++ D W +W GVQVPV + I P +K++ TR +++ PE+ Y++D +D +W+E+ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H + N+ + + P + LR+ + + K K +L + H F Q I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS EQ KN
Sbjct: 43 SDSTVFRTDLITAMKLHDSYQLNPED-FYVLADPWRQEW-EKGVQVPVNP---------EFI--PETVAREIAEKDKVVTFTRPRKYIRSSGSEPPELGYVDIQTLADAVCRYDLDEMDVAWLELINEEFKEMGMQQLDEYSMERVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALFCSLC-NEKLGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTEEDEVKFKSYCPKHGSTKKPENSHFCKSVNDGKGTCGASPTCLDGLRLLDVSQQDAKHGSQRKFKLQQLEDEFHTFVDVQEISQALKIPLDMTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYAKIS----EQEKN 540
BLAST of Protein Jade-1 vs. Ensembl Mouse
Match: Jade1 (jade family PHD finger 1 [Source:MGI Symbol;Acc:MGI:1925835]) HSP 1 Score: 276.944 bits (707), Expect = 3.458e-80 Identity = 182/543 (33.52%), Postives = 274/543 (50.46%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNV 1694
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I + + L+ +++ + S N F ++ + N
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA 566
BLAST of Protein Jade-1 vs. Ensembl Mouse
Match: Jade1 (jade family PHD finger 1 [Source:MGI Symbol;Acc:MGI:1925835]) HSP 1 Score: 276.944 bits (707), Expect = 3.458e-80 Identity = 182/543 (33.52%), Postives = 274/543 (50.46%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNV 1694
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I + + L+ +++ + S N F ++ + N
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA 566
BLAST of Protein Jade-1 vs. Ensembl Mouse
Match: Jade1 (jade family PHD finger 1 [Source:MGI Symbol;Acc:MGI:1925835]) HSP 1 Score: 276.944 bits (707), Expect = 3.458e-80 Identity = 182/543 (33.52%), Postives = 274/543 (50.46%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNV 1694
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I + + L+ +++ + S N F ++ + N
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA 566
BLAST of Protein Jade-1 vs. Ensembl Mouse
Match: Jade1 (jade family PHD finger 1 [Source:MGI Symbol;Acc:MGI:1925835]) HSP 1 Score: 276.944 bits (707), Expect = 3.458e-80 Identity = 182/543 (33.52%), Postives = 274/543 (50.46%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNV 1694
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I + + L+ +++ + S N F ++ + N
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA 566
BLAST of Protein Jade-1 vs. Ensembl Mouse
Match: Jade1 (jade family PHD finger 1 [Source:MGI Symbol;Acc:MGI:1925835]) HSP 1 Score: 265.388 bits (677), Expect = 4.522e-79 Identity = 170/487 (34.91%), Postives = 248/487 (50.92%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMM 1526
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R + D +
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVMIDTDTL 510
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Match: sp|Q6IE81|JADE1_HUMAN (Protein Jade-1 OS=Homo sapiens OX=9606 GN=JADE1 PE=1 SV=1) HSP 1 Score: 285.419 bits (729), Expect = 2.123e-82 Identity = 180/516 (34.88%), Postives = 273/516 (52.91%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PR+ E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I +L + L+ R++ +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGV 542
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Match: sp|Q6GQJ2|JADE1_XENLA (Protein Jade-1 OS=Xenopus laevis OX=8355 GN=jade1 PE=2 SV=1) HSP 1 Score: 278.1 bits (710), Expect = 6.998e-80 Identity = 178/500 (35.60%), Postives = 266/500 (53.20%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQH--SKKYQEPNTSESSVN------MGPRDIKELRI--XXXXXXXXXXXXXVNAKELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKK-------AHLFELMSKIS 1580
+EVF ITAM D N + + ++ D W +W GVQVPV E I + K F P K I H+ E + + + + + Y+++ +D +W+++ N E K +G+Q + E +E + E E+ CY ++ + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP RW L C LC GA IQCS K C+ AFHVTCA + L MK +VK +YC +H +KK ++ + S+ + P + LR+ Q+ + + + ++L + + F I IP D+ + I+ YW L+R +N + LI P E+NL ++ + I + F +R L+R R + M+ RREK K +F L +KIS
Sbjct: 41 SEVFRTDLITAMKLHDSNQLNPEDYYVLADPWRQEW-EKGVQVPVNP--EFIPETIARVIAEKDKVVTFTRPRKYI-HSSGSEPPEVGYVDIQTLADAVCRYDLNEMDVAWLQLINEEFKEMGMQQLDEYTMEQVLEEFEKKCYDKMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSGT-KWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSNRWALLCSLC-NEKVGACIQCSIKNCRTAFHVTCAFDHGLEMKTILTQEDEVKFKSYCPKHGSTKKPEDSHFCRSASDGKDTCEASPTFLGGLRVLEASQQNVKHGSQRKLKLQQLEDDFYSFVDVHDISQALKIPLDVTEYIYQYWKLRRKANFNEPLITPKKD-EEDNLAKKEQDVLIRRLQLFTHLRQDLERVRNLTYMVTRREKMKRSVCRVQEQIFNLYTKIS 531
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Match: sp|Q5E9T7|JADE1_BOVIN (Protein Jade-1 OS=Bos taurus OX=9913 GN=JADE1 PE=2 SV=1) HSP 1 Score: 269.626 bits (688), Expect = 7.895e-80 Identity = 171/483 (35.40%), Postives = 251/483 (51.97%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHS--KKYQEPNTSESSVNMG-----PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMM 1526
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ PE+ Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS +K +E ++ G PRD E ++ E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R D +
Sbjct: 45 SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEYVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKAEEGLGEGTAQENGAPECSPRDPLEPFAGLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVMTDTDTL 509
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Match: sp|Q6ZPI0|JADE1_MOUSE (Protein Jade-1 OS=Mus musculus OX=10090 GN=Jade1 PE=1 SV=2) HSP 1 Score: 276.944 bits (707), Expect = 2.419e-79 Identity = 182/543 (33.52%), Postives = 274/543 (50.46%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF----------LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-----------KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK--QLIDPLKS--IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNV 1694
+EVF ITAM D + D ++ D W +W GVQVPV I +P A+ + EK + R +++ P + Y+++ +D++W+E++N E K +G+ + E +E + E E+ CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C +C+LCP +GGAMK S KW H+SCA+WIPEV G+ + MEPIT+++ IP +RW L C LC GA IQCS K C+ AFHVTCA L MK N +VK +YC +HS QE ESS P+ E + E+ V ++L + EF L+D ++ +P ++ D ++ YW LKR N + LI P E+NL +R + + F +R L+R R + M+ RREK K + ++ +I + + L+ +++ + S N F ++ + N
Sbjct: 46 SEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEW-EKGVQVPVSPGT---------IPQPVARV---VSEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLC-NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPESS----PQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKD-EEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA 566
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Match: sp|Q7ZVP1|JADE3_DANRE (Protein Jade-3 OS=Danio rerio OX=7955 GN=jade3 PE=2 SV=1) HSP 1 Score: 273.863 bits (699), Expect = 1.397e-78 Identity = 184/511 (36.01%), Postives = 273/511 (53.42%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKY------EFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-KYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF-----PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
AEVF K I+AM D + S++ ++ D+W +W GVQV I +P+ + E L RKY + + ++ E+ E + Y++D +D W++ N E +G ++ E +E + E LER C++ + + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C + QC+LCP GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK +YC +HSK K EP S + + P + +L + A++L E EF P+++ L S+P + D IF YW +KR SN + L+ P EENL + SI M F +R L+R R + M+ RREK K + +I +L + +L N L++ L
Sbjct: 42 AEVFRKDLISAMKLPDSHHISSEDYYLLADTWKQEW-EKGVQVLASPDT---------IPQPSVRIITEKPKEVLFSKPRKYIQCWSQDSTETGYVNIKELAEAMCRYDLDDMDLYWLQQLNAELGMMGDGVVDELTMERVMEALERQCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNWLCRTC--VLGITPQCLLCPKTGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKVSHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSYCLKHSKPKAGEPGLSPAR-HKPPTETDKLSL--------------RAQKLQELEEEFYTYVHPEEVAHDL-SLPLHLLDFIFQYWKMKRKSNFNKALLPPKE--DEENLLLQPQEDSIHTRMRMFMHLRQDLERVRNLCYMVSRREKLKLSQSKAQEQIFNLHV-KLVNQELSAGL 519
BLAST of Protein Jade-1 vs. TrEMBL
Match: A0A4S2L8C9 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009057 PE=4 SV=1) HSP 1 Score: 416.001 bits (1068), Expect = 1.342e-129 Identity = 262/690 (37.97%), Postives = 376/690 (54.49%), Query Frame = 3
Query: 90 VEKLLNEYETEINYTKSKDSHAEVFDKHPITAM---SEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHI---GKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQE---------PNTSE--------SSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKEL--SETLHEFPKQLIDPLKS-------IPSDIKDKIFTYWTLKRTSNHFQCLI-KPPSIWSE------ENLKQ-------RINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLL----------DVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMI---ATNNPVSIVSNIPKEQLLISSKLKTDIYEKLKEPIFI 1976
V LLN++ T + + AE+FD HP++ M E + +D +++I ++W +W R+GVQVPV E ++S + + G P K I P KL F HC + Y+ID +D +WI I N ER CL L ++++ MLE I E LE+L + ++ K++E E + LE DEN++CD+C S EGEDGNELVFC+ CF+CVHQACYGIP LP GSWICR C+ ++ C LCPN GGAMK E D +W H+SCA+W+PEVGFG+++LMEP+ RL IPQAR NL C +C+ S GAPIQCS KKCK+AFHVTCA Q++L+M+QE + DV+L+ C +HS++ Q+ +TSE S N P ++ R+ + + ++ + S+T K L + IP DI+ I YW LKR +N + LI PPS W E E K+ + ++F ++RFGLDRARLVVDM+++RE++K LF M +IS LQ+ L N +++ D F STVHL D+VY N L D+ L+ + +L+ E L+ E +V + V K P + T +P S + IP EQL++ K DI ++L+ + +
Sbjct: 7 VTHLLNDW-TPTFFNEKDGKPAELFDAHPLSEMMVSPEAEVGKSDSLILIENNWRSEWHRNGVQVPVLPLGEMRRSGCRRMAMNGHPR-KLPYKINPSKLWHDVNDQRFDDSLHCILDARKRTSSSYQIDNLDYAWISIVNEERDCLDLPVVTDGMLEDIMEALEQLTFLKMHQKLKELEAQTLEFDENARCDICLSYEGEDGNELVFCDGCFLCVHQACYGIPRLPEGSWICRQCEAGVKSTTTCSLCPNTGGAMKMTE-DGTRWCHISCALWVPEVGFGDVELMEPVVRLENIPQARRNLLCSICR-SRYGAPIQCSNKKCKVAFHVTCAFQSNLIMRQEL-VDRDVRLVGLCLKHSRREQQVQPSKNDTSDHTSESPHKQAGHSPTNHIPPVSRQQRLLELENNFYSLVADIDVESWLSSKTTTGGMKAAKSDLSNNANKRLPIPEDIRRAITIYWRLKRCANFNKPLIYPPPSHWLELASKTVETTKEALAKAARLAAEQQAFDSFRRVRFGLDRARLVVDMVLQRERRKLALFRRMWRISELQMRILDNKHFSTLSISDRE------FFSTVHLGDSVYDNSTLLTKRKSTKIQGSDLKLKNTESSSSLSTQEHLQ-----TENSVPNSSACTIVNKQYEPPVGVREPRTASPHSSMGKIPYEQLIV----KEDIKQRLRSALAL 676
BLAST of Protein Jade-1 vs. TrEMBL
Match: A0A419PD52 (Protein Jade-1 OS=Clonorchis sinensis OX=79923 GN=Jade1 PE=4 SV=1) HSP 1 Score: 408.297 bits (1048), Expect = 1.291e-125 Identity = 256/690 (37.10%), Postives = 371/690 (53.77%), Query Frame = 3
Query: 90 VEKLLNEYETEINYTKSKDSH-AEVFDKHPITAM---SEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHI---GKPAAKTENFIMPEKLIRHTRKYEFLPEKHC--HMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQ--EPNTSESSVNMG---------------PRDIKELRIXXXXXXXXXXXXXVNAKEL--------------SETLHEFPKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLI-KPPSIWSE------ENLKQ-------RINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLL----------DVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMI---ATNNPVSIVSNIPKEQLLISSKLKTDIYEKL 1958
V LLN++ + KD AE+FD HP++ M E + +D +++I ++W +W R+GVQVPV + ++S + I G P K P KL F HC + + Y+ID +D +WI I N ER CL L +I++ MLE I E LE+L + ++ K++E E + LE DEN++CD+C S EGEDGNELVFC+ CF+CVHQACYGIP LP GSWICR C+ ++ C LCPN GGAMK E D +W H+SCA+W+PEVGFG+++LMEP+ RL IPQAR NL C +C+ S GAPIQCS KKCK+AFHVTCA Q++L+M+QE + DV+L+ C +HS++ Q +P T +S +M P ++ R+ + + ++ + S++ + K+L IP DI+ I YW LKR +N + LI PPS W E E K+ + ++F ++RFGLDRARLVVDM+++RE++K LF M +IS LQ+ L + +++ D F STVHL D+VY N L D+ L+ + +L+ E + E ++ V K P + T +P S + IP EQL+++ +K + L
Sbjct: 108 VTHLLNDWTP--TFLNEKDGKPAELFDAHPLSEMMVSPEAEVGKSDSLILIENNWRSEWHRNGVQVPVLPLSAMRRSGCRRIAVNGNPR-KLPYKTNPSKLWHDMNDQRFDDSLHCILDVRKRTPSSYQIDNLDYAWISIVNEERDCLDLPVITDAMLEDIMEALEQLTFLKMHQKLKELEAQTLEFDENARCDICLSYEGEDGNELVFCDGCFLCVHQACYGIPRLPEGSWICRQCEAGVKSTTTCSLCPNTGGAMKMTE-DGTRWCHISCALWVPEVGFGDVELMEPVVRLENIPQARRNLLCSICR-SRYGAPIQCSNKKCKVAFHVTCAFQSNLIMRQEL-VDRDVRLVGLCLKHSRREQQVQPPTDGTSGHMSESPHKQTGHSPTSHIPPVSRQQRLLELETNFYNLVADIDVESWLSGKTNTGGTKAAKSDSSNSVNKRL-----PIPEDIRRAITIYWRLKRCANFNKPLIYPPPSHWLELASKTVETTKEALAKAARLAAEQQAFDSFRRVRFGLDRARLVVDMVLQRERRKLALFRRMWRISELQMRVLDSKHFSTLSISDRE------FFSTVHLGDSVYDNSTLLTKHKSTKIQSSDLKLKNTESSSSLSTQEHFQ-----TENSIPTSSACTIVNKQCTSPICVREPRTASPHSSIGKIPYEQLIVTEDIKQRLRSAL 775
BLAST of Protein Jade-1 vs. TrEMBL
Match: A0A0X3NJA7 (Protein Jade-1 (Fragment) OS=Schistocephalus solidus OX=70667 GN=JADE1 PE=4 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 1.370e-121 Identity = 253/672 (37.65%), Postives = 370/672 (55.06%), Query Frame = 3
Query: 66 SMESHNEIVEKLLNEYETEINYTKSKDSHAEVFDKHPITAM--SEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTE--NFIMPEKLIRHTRKYEFLPEKHCHMPE---MHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQH-SKKYQ-------EPNTSE-SSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSE-----TLHEFP---------------KQLIDPLKS---IPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRI------------NNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNS-RLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMIATNNPVSIVSNIPKEQLLIS 1925
+M + + ++L E E N +++ AE+FD+HPI+ M +E + S ++ IT++W PDW +DGVQVP + + + P K + F +P KLIR TR EF H+ + + Y++D +D +W++ N ER+CLG + I + M+E IFE E + Y + + E + +E DEN++CDVC S EGEDGNELVFC+ C VCVHQACYGIP LP GSW+CR C+ +++C LCPN GGAMK L D W H+SCA+W+PEV FG+IDLMEP++RLN IPQAR NL C LC+ + GAPIQCS KKCK AFHVTCA QN LVM QE N DV+LLA+C +H SK+YQ P E S V+ + ++ + + +Q S+ N + L TL E+ +L+ K+ IP I + + TYW LKR SN Q L++ P W L ++ ++N F ++RFGLDRAR+V+DM+++RE++K L M +I++ QL + ++ LN++ +D + + H +++Y N D LL L + ++ T+P S + + M+T T I T NPV + ++ EQL++S
Sbjct: 39 TMGASEAVFQRLSEICECEPNVCQTRP--AELFDRHPISLMLVAENEFGSFPNLIKITNAWKPDWLKDGVQVPTRDPSSLPPVFVTKADLPTVKRKIATFPLPNKLIRCTRD-EFYDANLHHVSKKGVISSAFYQLDELDHAWLQTVNEERECLGEEKIQDWMIENIFETAEEIAYIKSKDDALSNEKKPIEFDENTRCDVCLSYEGEDGNELVFCDGCLVCVHQACYGIPTLPEGSWLCRRCEMGAKSTTRCALCPNTGGAMK-LVDDYTSWCHVSCALWVPEVAFGDIDLMEPVSRLNEIPQARKNLVCCLCRLRH-GAPIQCSVKKCKTAFHVTCAFQNGLVMLQEL-VNGDVRLLAHCPKHSSKEYQSRLSLLRSPKKKELSLVDTRSPNSTPVKKEGSFDKDQSHSRDANCQSLVRTEDVITLLEYEAKQKYSKKKHVTRDHSKLVHSPKADNVIPVGIIEHVLTYWRLKRCSNFNQPLMEAPEEWKTSVLPSQVPPSLATSTDPLAEATEVVNRFKRVRFGLDRARMVIDMVLQRERRKDALLRKMQQIANTQLRIIASTPDLNALPED------CLQVLISAHHGNSIYENYDALL--RLSDLNQPISPTRPMSPDVRRPETRPATTSSPSMRTTDNATAATAYIVTGNPV--IDSLRPEQLIVS 694
BLAST of Protein Jade-1 vs. TrEMBL
Match: G4VGV0 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_137970 PE=4 SV=1) HSP 1 Score: 395.586 bits (1015), Expect = 2.207e-121 Identity = 230/577 (39.86%), Postives = 332/577 (57.54%), Query Frame = 3
Query: 153 AEVFDKHPITAM---SEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKH--IGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF-LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKK-----------------YQEPNT------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKEL-------SETLHEFPKQLIDPL--KSIPSDIKDKIFTYWTLKRTSNHFQCLIKP-PSIWSE----------ENLKQRINNRSIMNAF---CKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVN 1727
AEVFD+HP++AM ++ + D +++I +SW +W R+GVQVPVK A+ Q + K + P + FIMPEKL + F H + + Y +D +D SWI N ER+CLG L+ + MLE + LE L Y +++ K++E + + LE DEN++CD+C S EGEDGNELVFC+ CF+CVHQACYGI ++P GSW+CR C+ ++ C LCPN GGAMK L D +W H+SCA+W+PEVGFG++++MEPI +L+ IPQAR NL C +C+ S GAP+QCS KCK AFHVTCA Q++LVM+QE + DV+L+ C +HS+K ++ PN+ + + G + + R Q+ E E F V L S +H ++ + +P+DI+ IF YW LKR +N Q L+ P P W E E L + S M AF +IRFGLDRARL+ DM+++RE++K LF+ M +IS +QL L+ + NS++ + + T H+ ++VY N + L N
Sbjct: 27 AEVFDRHPLSAMMISADSECGRKDNLVLILNSWKSEWYREGVQVPVKDASNQPRPVYKKLDVSCPKRRCPRFIMPEKLRVESTDGNFNETTHMLVKKRKNAPYYNVDDLDYSWIATVNEERECLGQVLVEDWMLEKVISALEYLTYVKMREKIKEIDVQSLEFDENARCDICLSFEGEDGNELVFCDGCFLCVHQACYGILQIPEGSWMCRQCEAGVKSTTPCSLCPNTGGAMK-LSDDGQRWCHVSCALWVPEVGFGDVEMMEPIIKLDNIPQARRNLLCSICR-SRYGAPVQCSSVKCKTAFHVTCAFQSNLVMRQEL-VDKDVRLIGLCWKHSRKEQQSATHHSSASCDSNSFRAPNSPIKVHDANQNFGSGMQPVALTRKQRLLELECNFHNLVQESHLNIWLDNDSMKMHLGNSAFLNEGEHRHVPNDIRAAIFVYWRLKRRANFNQPLVNPAPLTWKESADQVAATTKEELARVERANSDMKAFESFKRIRFGLDRARLMADMVLQRERRKLALFKRMWRISEIQLSALE--KQNSLISSE--------LLRTAHIGESVYDNWELFLAYN 590
BLAST of Protein Jade-1 vs. TrEMBL
Match: A0A3Q0KMX3 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 395.201 bits (1014), Expect = 2.427e-121 Identity = 230/577 (39.86%), Postives = 332/577 (57.54%), Query Frame = 3
Query: 153 AEVFDKHPITAM---SEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKH--IGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEF-LYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKK-----------------YQEPNT------SESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKEL-------SETLHEFPKQLIDPL--KSIPSDIKDKIFTYWTLKRTSNHFQCLIKP-PSIWSE----------ENLKQRINNRSIMNAF---CKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVN 1727
AEVFD+HP++AM ++ + D +++I +SW +W R+GVQVPVK A+ Q + K + P + FIMPEKL + F H + + Y +D +D SWI N ER+CLG L+ + MLE + LE L Y +++ K++E + + LE DEN++CD+C S EGEDGNELVFC+ CF+CVHQACYGI ++P GSW+CR C+ ++ C LCPN GGAMK L D +W H+SCA+W+PEVGFG++++MEPI +L+ IPQAR NL C +C+ S GAP+QCS KCK AFHVTCA Q++LVM+QE + DV+L+ C +HS+K ++ PN+ + + G + + R Q+ E E F V L S +H ++ + +P+DI+ IF YW LKR +N Q L+ P P W E E L + S M AF +IRFGLDRARL+ DM+++RE++K LF+ M +IS +QL L+ + NS++ + + T H+ ++VY N + L N
Sbjct: 27 AEVFDRHPLSAMMISADSECGRKDNLVLILNSWKSEWYREGVQVPVKDASNQPRPVYKKLDVSCPKRRCPRFIMPEKLRVESTDGNFNETTHMLVKKRKNAPYYNVDDLDYSWIATVNEERECLGQVLVEDWMLEKVISALEYLTYVKMREKIKEIDVQSLEFDENARCDICLSFEGEDGNELVFCDGCFLCVHQACYGILQIPEGSWMCRQCEAGVKSTTPCSLCPNTGGAMK-LSDDGQRWCHVSCALWVPEVGFGDVEMMEPIIKLDNIPQARRNLLCSICR-SRYGAPVQCSSVKCKTAFHVTCAFQSNLVMRQEL-VDKDVRLIGLCWKHSRKEQQSATHHSSASCDSNSFRSPNSPIKVHDANQNFGSGMQPVALTRKQRLLELECNFHNLVQESHLNIWLDNDSMKMHLGNSAFLNEGEHRHVPNDIRAAIFVYWRLKRRANFNQPLVNPAPLTWKESADQVAATTKEELARVERANSDMKAFESFKRIRFGLDRARLMADMVLQRERRKLALFKRMWRISEIQLSALE--KQNSLISSE--------LLRTAHIGESVYDNWELFLAYN 590
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Match: jade1 (jade family PHD finger 1 [Source:NCBI gene;Acc:327437]) HSP 1 Score: 285.034 bits (728), Expect = 2.147e-83 Identity = 180/500 (36.00%), Postives = 273/500 (54.60%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF--PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSI 1625
+EVF ITAM D N D +++D W +W GVQVPV S + K ++ + ++ F P+KLIR T E + + + E + Y+++ D +W+E++N E +G+QL+ E +E + E ER CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C S +C LCP +GGAMK S KW H+SCA+WIPEV GN + MEPIT ++ IP RW L C LCK TGA IQCS K C++AFHVTC +Q L M + +VK ++C HS + + ++ + G R ++ + + + ++L + + F P ++ L+ +P++ D +F YW LKR ++ Q L+ P EE+L +R + + F +R L+R R + M+ RREK K + + +I + L+ RL+ +
Sbjct: 66 SEVFRTDLITAMKLHDSYQLNPED-YYVLSDPWRQEW-EKGVQVPV-SPHSIPKPTVRVVADKSSALL-FTRPKKLIR-TWGAEASALGYVAIGTLSEGMCRYDLNEEDVAWLELANKEFSAMGMQLLDENTMERVMEEFERHCYDNMSHAMETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGISPKCQLCPKKGGAMKPTRSG-SKWVHVSCALWIPEVSIGNPEKMEPITSVSQIPNNRWALICCLCK-EKTGACIQCSAKSCRVAFHVTCGLQFGLKMNTILTDDDEVKFKSFCPTHSGMDWTDSYAGANEDGGIR-VRGVN-AADPCGAHLSERKLRVQQLEDEFYRFVAPDEVAKHLR-LPAETVDFLFQYWKLKRKASFNQPLVTPKRE-EEESLARREQEVLLRRLRLFTHLRQDLERVRNLTYMVTRREKIKRSVCRVQEQIFHHHVRLLEQGRLSGV 552
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Match: jade1 (jade family PHD finger 1 [Source:NCBI gene;Acc:327437]) HSP 1 Score: 275.789 bits (704), Expect = 6.288e-80 Identity = 181/498 (36.35%), Postives = 270/498 (54.22%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDP---NSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF--PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLN 1619
+EVF ITAM D N D +++D W +W GVQVPV S + K + K +A F P+KLIR T E + + + E + Y+++ D +W+E++N E + +QL+ E +E + E ER CY + + E +E+DE+ CDVCQSP+GEDGNE+VFC+ C +CVHQACYGI ++P GSW+CR C S +C LCP +GGAMK S KW H+SCA+WIPEV GN + MEPIT ++ IP RW L C LCK TGA IQCS K C++AFHVTC +Q L M + +VK ++C HS + + ++ + G R ++ + + + ++L + + F P ++ L+ +P++ D +F YW LKR ++ Q L+ P EE+L +R + + F +R L+R R + M+ RREK K + + +I + L+ RL+
Sbjct: 37 SEVFRTDLITAMKLHDSYQLNPED-YYVLSDPWRQEW-EKGVQVPV-SPHSIPKPTVVVADKSSALL--FTRPKKLIR-TWGAEASALGYVAIGTLSEGMCRYDLNEEDVAWLELANKEFSAM-MQLLDENTMERVMEEFERHCYDNMSHAMETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGISPKCQLCPKKGGAMKPTRSG-SKWVHVSCALWIPEVSIGNPEKMEPITSVSQIPNNRWALICCLCK-EKTGACIQCSAKSCRVAFHVTCGLQFGLKMNTILTDDDEVKFKSFCPTHSGMDWTDSYAGANEDGGIR-VRGVNA-ADPCGAHLSERKLRVQQLEDEFYRFVAPDEVAKHLR-LPAETVDFLFQYWKLKRKASFNQPLVTPKRE-EEESLARREQEVLLRRLRLFTHLRQDLERVRNLTYMVTRREKIKRSVCRVQEQIFHHHVRLLEQGRLS 519
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Match: jade3 (jade family PHD finger 3 [Source:NCBI gene;Acc:322209]) HSP 1 Score: 266.159 bits (679), Expect = 8.067e-77 Identity = 183/510 (35.88%), Postives = 268/510 (52.55%), Query Frame = 3
Query: 156 EVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIG-KPAAKTENFIMPEKLIRHTRKY------EFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSIL 1628
+VF K I+AM D + S + ++ D+W +W GVQV + S + + I+ I KP E L RKY + + ++ E+ E + Y++D +D W++ N+E +G + E +E E LER C+ + + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C QCILCP +GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK +YC +HSK T ES ++ E + A++L E EF K L+ P + +P + D I+ YW LKR +N + L+ P EENL + SI M F +R L+R R + M+ RREK K + +I +L + +L N L++ L
Sbjct: 27 QVFRKDLISAMKLPDSHHISPEDYYLLADTWRQEW-EKGVQV-LASPDTIPQPSIRIIAEKPK---------EILFSRQRKYIQCWSQDSTETGYVNIKELAEAMCRYDLDDMDLYWLQELNIELGQMGEGFMDELTMERAMEALERKCHDNMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNWLCRTC--VLGIDPQCILCPKKGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKVSHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSYCLKHSKS----KTGESGLSPARHKPTE-----------TEKVGLRAQKLQELEEEFYK-LVQPEEVAQDLGLPPHLLDFIYQYWKLKRKTNFNKALLPPKE--DEENLLLQPQEDSIHTRMRMFMHLRQDLERVRNLCYMVSRREKLKLSQSKAQEQIFNLHV-KLVNQELSAGL 502
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Match: jade2 (jade family PHD finger 2 [Source:ZFIN;Acc:ZDB-GENE-120215-66]) HSP 1 Score: 256.914 bits (655), Expect = 6.253e-73 Identity = 171/508 (33.66%), Postives = 271/508 (53.35%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPNST----DRVLIITDSWTPDWCRDGVQVP--VKSANEQKKSEIKHIGKPA--AKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESS----VNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQ---LIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEE--NLKQRINN--RSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLK 1604
+EVF ITAM P+ST + I++DSW +W GVQVP V++ E+ + + + T + E R +R + + Y++D +D +W+++ N E + L L + E +E + +LE C +++Q + E +E+DE+ CDVC+SPEGEDGNE+VFC+ C +CVHQACYGI ++P G+W+CR C +C+LCP RGGA+K S KW H+SCA+WIPEV G + MEPIT+++ IP +RW L CHLC+ TG IQCS C +AFHVTCA + L M+ N +V+ ++C +HS + +E GP +E + + + ++ S+ A + + L E + L+DP +P D ++ +W L+R +N + L+ S+ ++ NL Q+ + + F +R L+R R + M+ RRE+ K +L + KI +LQ++ L+
Sbjct: 64 SEVFRTDFITAMKL--PDSTQLNPEDFYILSDSWRQEW-EKGVQVPANVEAIPIPVVRELPEVSRIPFYSPTYSGDQSESGFRSSRILQDSGSR-----------YDLDDLDVTWLDLVNAEFRELALPELDELTMERVLVVLEIRCEEKMQEAIEAQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNICVHQACYGIMKVPQGNWLCRTC--ALGVQPKCLLCPKRGGALKPTRSGT-KWIHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCHLCR-ELTGTCIQCSMPSCVVAFHVTCAFDHGLEMRTLLAENDEVRFKSFCLEHSGVSRPTGGAERDQSRHCGTGPSG-REPALVQSERSDRDQSEVQKASQRKQKLQELEDEFYRLVDPKDVAESLGLPDAHADFLYQFWKLRRRANFNRPLV---SLNRDQVDNLDQQEQDVLYRRLRLFTHLRQDLERVRNLCYMVTRRERIKHNLCSVQEKIFNLQIQLLE 549
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Match: brd1b (bromodomain-containing protein 1-like [Source:NCBI gene;Acc:103023471]) HSP 1 Score: 213.001 bits (541), Expect = 4.544e-57 Identity = 103/283 (36.40%), Postives = 161/283 (56.89%), Query Frame = 3
Query: 318 HIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQE--------FQANMDVKLLAYCKQHS 1142
+ +P KT + +P R + ++++ + + E E Y++D D +W+E+ N +RK G +S+ + E + + E+ + Q +V DE++ C +C E ++ N ++FC+ C + VHQ CYG+P +P G W+CRHC + P++ ++CI CPN+GGA+K+ +D+D+W H+ CA+W+PEVGF N +EPI + IP ARW L C+LCK GA IQCS+ C AFHV+CA + L MK E VK AYC H+
Sbjct: 111 RLPEPKIKTVEYNLPAVPRRPSAYFKYVEKTSEELDE--EVEYDMDEEDYAWLELINEKRKSEGYSQVSQNVFEFLMDRFEKESFFESQGQVDPQSL----IDEDAVCCICMDGECQNSNAILFCDMCNLAVHQECYGVPHIPEGQWLCRHCLQSPSQPAECIFCPNKGGALKR--TDDDRWGHVVCAIWVPEVGFTNTLFIEPIDGVANIPPARWKLTCYLCKERGVGACIQCSKANCYTAFHVSCAQKAGLYMKMEPIKEVTDTGSTTFTVKKTAYCCSHT 385
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008687.1 (pep scaffold:Pmarinus_7.0:GL495059:436:1819:-1 gene:ENSPMAG00000007864.1 transcript:ENSPMAT00000008687.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 132.494 bits (332), Expect = 3.246e-36 Identity = 70/135 (51.85%), Postives = 85/135 (62.96%), Query Frame = 3
Query: 504 LGLQLISETMLEIIFEILERLCYKRIQSKVREAETEF---LEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEV 899
LGL + E LE LER C S +R TE +E D + CDVC+SP EDGNE+VFC+ C VCVHQACYGI +P+GSW+CR CD+ + +C LCP R GAMK KWAH+SCA+WIPEV
Sbjct: 19 LGLPPVRERSLEAALSRLERRC---ADSALRALSTEAALGIEFDADVVCDVCRSPHAEDGNEMVFCDKCDVCVHQACYGIACVPAGSWLCRVCDRGV-AAPRCQLCPRRDGAMKPTRGG-GKWAHVSCALWIPEV 148
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Match: mllt10 (MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:ZFIN;Acc:ZDB-GENE-041114-176]) HSP 1 Score: 144.436 bits (363), Expect = 1.173e-35 Identity = 76/184 (41.30%), Postives = 106/184 (57.61%), Query Frame = 3
Query: 633 SKCDVCQSPEGEDGNELVFCED--CFVCVHQACYGIPELPSGSWICRHCDKCPNESS-QCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCK------TSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQE 1157
C VC G N LV+C+ C V VHQACYGI +P+G W CR C+ + +C LCP++ GA+K+ +D WAH+ CA++IPEV F N+ MEPI L +P R+N C+LC+ + TGA + C++ C+ AFHVTCA L+ ++E +VK YCK H K Q+
Sbjct: 7 GGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVHVPTGPWFCRKCESQERAARVRCELCPHKDGALKR--TDNGGWAHVVCALYIPEVQFANVSTMEPIV-LQYVPHDRYNKTCYLCEEQGRESKAATGACMTCNKHGCRQAFHVTCAQMAGLLCEEEGVGADNVKYCGYCKYHYSKMQK 187
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Match: phf14 (PHD finger protein 14 [Source:ZFIN;Acc:ZDB-GENE-030131-1796]) HSP 1 Score: 97.0561 bits (240), Expect = 6.953e-21 Identity = 58/185 (31.35%), Postives = 91/185 (49.19%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFCEDCFVCVHQACYGI-----------PELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLR-CHLCKT---SNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKK 1148
C VC ED NE+V C++C V VH+ACYG+ + + W C C S C LCP G K E+D +W H+ CA+++ V F +++ + P+T L + +++ + C LC+ S TG I C C+ FHV CA + L+ + + + A+CKQH+ +
Sbjct: 282 CSVCLGENSEDSNEIVQCDNCGVTVHEACYGVDGESESVISSTSDNSTEPWFCDPCKAGVVPS--CELCPAIDGIFK--ETDAGRWVHVVCALYVSGVAFEDVERLRPVT-LTEMSYSKYGAKECMLCEERLFSRTGVCINCDAGMCRSFFHVMCAQREGLLSEAAAEEEIADPFFAHCKQHADR 461
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Match: KDM4C (lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]) HSP 1 Score: 92.0485 bits (227), Expect = 2.147e-19 Identity = 52/144 (36.11%), Postives = 77/144 (53.47%), Query Frame = 3
Query: 666 EDGNE-LVFCEDCFVCVHQACYGI-PELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSN---TGAPIQCSEKKCKMAFHVTCAIQNSLVM 1082
EDG L+ C C + VH +CYG+ + S W C C + C LC RGGA++Q + +++W H+ CAV + E F N+ P+ ++ IP RW L+C C+ + GA +QCS +C FHVTCA ++M
Sbjct: 468 EDGTSTLISCAKCCLQVHASCYGVGAQSLSDGWKCSRC-AAEAWTVDCCLCNLRGGALQQ--TTDNRWVHVMCAVAVTEARFVNVMERRPVD-ISRIPPPRWKLKCIFCRKQHRKVQGACVQCSYGRCPTPFHVTCAHAAGVLM 607
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Match: KDM4C (lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]) HSP 1 Score: 75.8702 bits (185), Expect = 3.794e-15 Identity = 40/110 (36.36%), Postives = 62/110 (56.36%), Query Frame = 3
Query: 771 CDKCPNE--SSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSN---TGAPIQCSEKKCKMAFHVTCAIQNSLVMK 1085
C +C E + C LC RGGA++Q + +++W H+ CAV + E F N+ P+ ++ IP RW L+C C+ + GA +QCS +C FHVTCA ++M+
Sbjct: 2 CSRCAAEAWTVDCCLCNLRGGALQQ--TTDNRWVHVMCAVAVTEARFVNVMERRPVD-ISRIPPPRWKLKCIFCRKQHRKVQGACVQCSYGRCPTPFHVTCAHAAGVLME 108
BLAST of Protein Jade-1 vs. Ensembl Yeast
Match: NTO1 (Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 [Source:SGD;Acc:S000006235]) HSP 1 Score: 147.132 bits (370), Expect = 5.583e-37 Identity = 68/179 (37.99%), Postives = 101/179 (56.42%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK------QEFQAN---MDVKLLAYCKQHSKK 1148
C VC + ++ N +VFC+ C + VHQ CYGI +P G W+CR C N + C++CP+ GA KQ +D W H CA+W+PE+ F N+ MEPI + + +RW L C++CK GA IQC ++ C A+HVTCA + L M QE +N + ++C +H+ +
Sbjct: 266 CAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQ--TDTGSWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICK-KKMGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAPR 441
BLAST of Protein Jade-1 vs. Ensembl Yeast
Match: SNT2 (Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitination, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003099]) HSP 1 Score: 75.485 bits (184), Expect = 2.807e-14 Identity = 57/225 (25.33%), Postives = 97/225 (43.11%), Query Frame = 3
Query: 549 EILER-LCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGI---------PELPSGSWICRHCDKCPNE-------SSQCILCPNRGGAMKQLESDEDK-------------WAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQ-ANMDVKLLAYC 1130
++LE+ + K ++K + +T + + + C VC+ ++ N V C +C + VH CY I L + W+ CD C N+ + QC +CP + + S K W HL C+++ ++ +GN M+P + C +C+ N G ++C+ KC+ +H+TCA QNS K F+ NM V C
Sbjct: 1010 KMLEKDMILKHTKNKPKNPDTAWANNSARTFCSVCKEKFNDNDNYEVVCGNCGLTVHYFCYAIKLPKDMKKNTNLKTFKWL---CDPCSNDLNPIISTTYQCSMCPTKDYDYDRYRSQSFKICPDALKCTSLGTWVHLVCSLFNEDIKYGNGQSMQPALNTTAVLIKHSRFTCGVCRI-NGGGLVKCN--KCQYRYHITCA-QNSSNFKLMFEKKNMSVDTTLPC 1227
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Match: EDO49715 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFG5]) HSP 1 Score: 240.736 bits (613), Expect = 5.575e-71 Identity = 159/493 (32.25%), Postives = 250/493 (50.71%), Query Frame = 3
Query: 156 EVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWI-EISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANM--DVKLLAYCKQHSKKYQEPNTSESSVNMGPR---DIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQL----IDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI-------MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKI 1577
++F I+AM D +T+ + ITD+W +W R GVQV ++ Q + E +P K ++ K + + +Y+++ D W+ ++++ CLG + E LE +E CY+ + + + +E+DE+ CDVCQSPE E+GNE+VFC+ C +CVHQACYGI +PSGSW+C+ C + C LC GGAMK+ + + + H+SCA+W+PEVGFGN++ MEPI ++ IP +RWNL C+LCK GA IQCS K C AFHVTC Q L M+ V+ ++YC +H K + P S PR + R ++ + +++ ++ K L + EF + I ++P ++ I YWTLKR + L+ PP+ +E L + I + K+R L+R R + M+ +REK + LF + ++
Sbjct: 3 QIFRTDLISAMKLPDSQILNTENYMSITDTWRQEWER-GVQV----SSSQTRGE-------------GCIPPKFLKADEKKK----------SRTQCIYDLNRTDVEWLTALNSITLSCLGKTELDEGTLEKAIAYMEDKCYENMGYAIVTQKGLSIEYDESVCCDVCQSPESEEGNEMVFCDSCDICVHQACYGIQSIPSGSWLCQPC-RWGVAKPPCKLCSACGGAMKKAKGGKT-YIHVSCALWVPEVGFGNVERMEPIIKVEKIPTSRWNLVCYLCK-EKVGACIQCSVKSCVTAFHVTCGFQEGLDMRTILDDTEVDGVRHVSYCSKHGYKNKSPGKSPGRPPKSPRKSPNKSPPRSPEKIKQDKEEAENQRQKRLKQMEGEFYNYVDVGEIAKDLALPKELASHIHAYWTLKRKARDDVPLV-PPTPQQQEKLSGKQGAADISKNLQVQIERLMKMRCDLERLRNLCYMVGKREKMRRELFRVRERV 463
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Match: EDO40569 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Q6]) HSP 1 Score: 211.075 bits (536), Expect = 1.550e-57 Identity = 159/528 (30.11%), Postives = 260/528 (49.24%), Query Frame = 3
Query: 210 TDRVLII--TDSWTPDWCRDGVQVPVKS---ANEQKKSEIKHIGKPAAKTE-----------NFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQE----FQANMDVKLLAYCKQHSKKYQEPNT--------------SESSVNMG---PRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIK--PPSIWSEENLKQRINNRS--------IMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLK---NSRLNSILKDDPS 1643
TDR+ ++ T+S PD D + P + + + K++ K PA KTE F +P+ R T + F+ + M EM E Y++D D +W++ N +RK + +S+ + E + + LE+ Y +S+ +++ DE++ C +C E ++ N ++FC+ C + VHQ CYG+P +P G W+CR C + P+ C+LCPN+ GA KQ +D+ +W H+SCA+WIPEV F N +EPI ++ IP ARW L C++CK GA IQC + C AFHVTCA Q L MK E ++ V+ A+C HS E N S+++V G R IK+ R + E + VN + H K + + + + +YW LKR S + L++ + S++ + RS ++ + ++R L+RARL+V+++ +REK K ++ + L+L+ L L+ + DP
Sbjct: 107 TDRLGVVEETESKEPDRIEDSEEPPPQKPVSKSTKSKNKNKTKQTPAKKTELPLAVYCEADEAFCLPDAPARPTTYFRFIEQTTEEMDEMVE--YDMDEEDYAWLDFVNDKRKADSIAPVSQEVFETLMDRLEKESY--FESQTTCDPNQYI--DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRVVDCVLCPNKTGAFKQ--TDDGRWGHVSCALWIPEVCFANTVFLEPIDSIDNIPSARWKLTCYICK-RRQGACIQCFKTNCYTAFHVTCAQQAGLYMKIEPVKGENGHITVRKNAFCDIHSPNSSEENEGEERSEEEKTKEVKSKAAVKTGKTNKRSIKKFR-KLLSEKKTMPVPVVNIPFIPA--HRLGKIVSRVAMAKKAQFVHALQSYWMLKRQSRNGVPLLRRLQATHLSQKGTGDESSERSERIRAMKEQLHFWQRLRHDLERARLLVELIRKREKLKREHVKVKQHVVDLKLQPLNIVLRKTLDQVQTKDPG 622
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Match: EDO43778 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXH9]) HSP 1 Score: 133.65 bits (335), Expect = 8.210e-36 Identity = 75/180 (41.67%), Postives = 106/180 (58.89%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFCED--CFVCVHQACYGIPELPSGSWICRHCDKCPNESS-QCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLC----KTSNT--GAPIQCSEKKCKMAFHVTCAIQNSLVMKQ-EFQANMDVKLLAYCKQHSKK 1148
C VC G D N LV+C+ C V VHQACYGI ++P G W CR C+ + +C LCP++ GA+K+ +D WAH+ CA++IPEV FGN+ MEPI L ++P R+ C++C K S T G + C++ CK FHVTCA L+ ++ + Q+ VK + YC+ H K
Sbjct: 9 CCVCSDERGWDENPLVYCDGHGCNVAVHQACYGIVQVPKGPWFCRKCESQERIARVKCELCPSKVGALKR--TDNGGWAHVVCALYIPEVRFGNVSTMEPIL-LASVPHERYLKTCYICEERGKESRTAHGGCMNCNKLGCKQTFHVTCAQSCGLLCEENDGQSGPTVKYVGYCQFHWNK 185
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Match: EDO35083 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMJ1]) HSP 1 Score: 63.1586 bits (152), Expect = 2.924e-10 Identity = 38/119 (31.93%), Postives = 58/119 (48.74%), Query Frame = 3
Query: 861 WAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLC----KTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-KYQEPNTSESSVNMGPRDI 1202
W H++CA+ +PE F +I IT IP AR LRC +C + A +QC KC +FHVTC + S ++ ++ + YC +H + KY+ S + +G R I
Sbjct: 317 WVHIACAITLPEAEFTDIGNRSGIT-TEKIPPARRKLRCSICNEPPASVTRSACVQCCAGKCATSFHVTCCLLTSKPLE---PSDWPQPISTYCGRHRRDKYKAAERDFSEIGVGERVI 431
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Match: EDO30859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYF7]) HSP 1 Score: 48.9062 bits (115), Expect = 7.496e-6 Identity = 36/133 (27.07%), Postives = 56/133 (42.11%), Query Frame = 3
Query: 789 ESSQCILC-------PNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWN---LRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQE 1157
++ +C LC P R G + L S D+W H++C +W EV + RL + A ++C LC GA + C E +C M +H C V + + + YC QHS + +E
Sbjct: 473 DTRKCQLCNRLGDDEPTRAGRL--LYSALDEWVHINCGLWSAEV------FEDDEGRLQNVQAAVTRGKMMKCELC--GEAGATVGCCENRCPMNYHFMCGRDAEAVYQDDKK--------VYCAQHSFRAKE 587
BLAST of Protein Jade-1 vs. Ensembl Medaka
Match: jade1 (jade family PHD finger 1 [Source:NCBI gene;Acc:101155976]) HSP 1 Score: 266.159 bits (679), Expect = 3.842e-76 Identity = 183/524 (34.92%), Postives = 265/524 (50.57%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVD--PNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSK-KYQEP---------------------------NTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEF--PKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI--MNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNS 1622
+EVF ITAM D P + + ++ D W +W GVQVPV + + + + K FI P+KLIR T E L Y+++ D +W++I N E +GL L+ E +E E ER CY + + E +E+DE+ CDVCQSP+GED NE+VFC+ C +CVHQACYGI ++P GSW+CR C +C LCP +GGAMK S KW H+SCA+WIPEV GN + MEPIT ++ IP RW L C LCK GA IQCS K C+ AFHVTC +Q +L M + +VK ++C +HS + EP SS + D + L ++ ++ + + +E+ E + F +++ LK +P ++ D ++ YW LKR +N Q L+ P EE+L +R + + F +R L+R R + M+ RREK K L+++ +I Q+ L LN
Sbjct: 37 SEVFRTDLITAMKLHDSHPLNPEDYFVLADPWRQEW-EKGVQVPV--SPQSIPQPVTRVLVEKEKELMFIRPKKLIR-TSGTEALGYVDIRTLADGVCRYDLNEEDVAWLQIVNEEFAEMGLPLLDENTMERAMEEFERRCYDNMTHAMETEEGLGIEYDEDVVCDVCQSPDGEDNNEMVFCDKCNICVHQACYGIQKVPQGSWLCRIC--ALGILPKCQLCPKKGGAMKPTRSG-TKWVHVSCALWIPEVSIGNPEKMEPITNVSHIPSNRWALICCLCK-EKAGACIQCSAKNCRTAFHVTCGLQANLEMNTILTEDDEVKFKSFCPKHSGHQGAEPRDQESEDEEEEEEAAGHKKGRKGGVTRGGDASSYPLPSYDQEGL----SQQEKRVSLRKLKLQEMEEDFYRFVEVEEVAGSLK-LPPEVLDFLYQYWKLKRKANFNQPLLTPKKD-EEESLARREQEVLLRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSLWKVQEQILQQQVVLLDQELLNG 546
BLAST of Protein Jade-1 vs. Ensembl Medaka
Match: jade3 (jade family PHD finger 3 [Source:NCBI gene;Acc:101168361]) HSP 1 Score: 259.61 bits (662), Expect = 1.395e-74 Identity = 175/496 (35.28%), Postives = 259/496 (52.22%), Query Frame = 3
Query: 105 NEYETEINYTKSKDSH-AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRK------YEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKK 1547
N+Y+++ S AEVF K I+AM D + S + ++ D+W W GVQVP I +P+ + E L H RK E + ++ E+ E + Y++D +D W++ N E +G + I E +E E LE+ C+ ++ + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C QC+LCP +GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK ++C +HSK P + E+ ++ R + E + + +EL E + Q + L + I D I+ YW LKR SN + L+ P EEN + + S+ M F +R L+R R + M+ RREK K
Sbjct: 26 NKYDSKPGTPASNPKKPAEVFRKDLISAMKLPDSHHISPEDFYLLADTWKQKW-EKGVQVPASPDT---------IPEPSVRVIAEKSKEMLFSHQRKNIQCSGQESAEPGYVNIRELAEAMCPYDLDDMDLYWLQALNQELVLMGEEPIDELTMERAMEALEKHCHDNMKHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPVGNWLCRTC--VLGILPQCLLCPQKGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSFCLKHSK----PKSGEAGLSPA-------RSKPPGEVGKVGQRAQRLQELEEEFYTLVHLQEVAQLLRLSERILDFIYQYWKLKRKSNFNKPLLPPK---EEENGVLQPHEDSVHTRMRMFMHLRQDLERVRNLCYMVSRREKLK 493
BLAST of Protein Jade-1 vs. Ensembl Medaka
Match: jade3 (jade family PHD finger 3 [Source:NCBI gene;Acc:101168361]) HSP 1 Score: 258.84 bits (660), Expect = 3.122e-74 Identity = 175/496 (35.28%), Postives = 259/496 (52.22%), Query Frame = 3
Query: 105 NEYETEINYTKSKDSH-AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRK------YEFLPEKHCHMPEMHEFL--YEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPK-QLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSI---MNAFCKIRFGLDRARLVVDMMVRREKKK 1547
N+Y+++ S AEVF K I+AM D + S + ++ D+W W GVQVP I +P+ + E L H RK E + ++ E+ E + Y++D +D W++ N E +G + I E +E E LE+ C+ ++ + E +E+DE+ CDVC+SP+ E+GN++VFC+ C +CVHQACYGI ++P G+W+CR C QC+LCP +GGAMK + KWAH+SCA+WIPEV + MEPIT+++ IP +RW+L C LCK TGA IQCS K C + FHVTCA ++SL MK +VK ++C +HSK P + E+ ++ R + E + + +EL E + Q + L + I D I+ YW LKR SN + L+ P EEN + + S+ M F +R L+R R + M+ RREK K
Sbjct: 40 NKYDSKPGTPASNPKKPAEVFRKDLISAMKLPDSHHISPEDFYLLADTWKQKW-EKGVQVPASPDT---------IPEPSVRVIAEKSKEMLFSHQRKNIQCSGQESAEPGYVNIRELAEAMCPYDLDDMDLYWLQALNQELVLMGEEPIDELTMERAMEALEKHCHDNMKHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPVGNWLCRTC--VLGILPQCLLCPQKGGAMKATRAG-TKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWSLICSLCKL-KTGACIQCSVKNCTIPFHVTCAFEHSLEMKTILDEGDEVKFKSFCLKHSK----PKSGEAGLSPA-------RSKPPGEVGKVGQRAQRLQELEEEFYTLVHLQEVAQLLRLSERILDFIYQYWKLKRKSNFNKPLLPPK---EEENGVLQPHEDSVHTRMRMFMHLRQDLERVRNLCYMVSRREKLK 507
BLAST of Protein Jade-1 vs. Ensembl Medaka
Match: jade2 (jade family PHD finger 2 [Source:NCBI gene;Acc:101162062]) HSP 1 Score: 253.832 bits (647), Expect = 1.777e-71 Identity = 173/532 (32.52%), Postives = 268/532 (50.38%), Query Frame = 3
Query: 153 AEVFDKHPITAMSEVDPN--STDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQH------------------SKKYQEPNTSE---------------SSVNMGPRDIKEL-RIXXXXXXXXXXXXXVNAKELSETLHEFPK---QLIDPLK-----SIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEE--NLKQRINN--RSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLK 1604
+EVF ITAM D D +++D W +W GVQVP AN++ E PA+ E L + R+ + E H P+ + Y++D +D +W+++ N+E + + L + E +E + +E +C +++Q + E +E+DE+ CDVC+SPEGEDGNE+VFC+ C VCVHQACYGI ++P G+W+CR C +C+LCP RGGA+K S KW H+SCA+WIPEV G + MEPIT+++ IP +RW L C LC+ +TG IQCS C +AFHVTCA + L MK N +V+ ++C +H + P+T ++ PR L + + E+ + + + L E Q +DP + +P D ++ +W LKR +N + L+ ++ +E NL Q+ + + F +R L+R R + M+ RREK K L +L +I LQ++ L+
Sbjct: 49 SEVFRTDFITAMKLPDSAQLGPDDFYVLSDPWRQEW-EKGVQVP---ANQEAIPEPVVRCLPASLAE-------LSNNGRQKDG--ESHFSRPQPYT-CYDLDDLDVAWLQLVNLEFRQMALPELDELTMECVLVEMESVCQEKMQQAIETEEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPQGNWLCRTC--ALGVQPKCLLCPKRGGALKPTRSGT-KWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLCR-EHTGTCIQCSMPSCIVAFHVTCAFDHGLEMKTILAENDEVRFKSFCLEHSCSTSSSSGVSNGDCVNGAHAAARPDTRHGVGDGLLTDQTRNPNGGADLEPRSTSHLVSVSASERAERDQLEREKVSQRKQKLQELEDEFYQFVDPREVAENLGLPISQVDFLYQFWKLKRKANFNRPLV---TLKRDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRREKMKHSLCDLQERIFHLQIQLLE 559
BLAST of Protein Jade-1 vs. Ensembl Medaka
Match: brd1b (bromodomain-containing protein 1 [Source:NCBI gene;Acc:101163229]) HSP 1 Score: 217.238 bits (552), Expect = 2.202e-58 Identity = 114/311 (36.66%), Postives = 170/311 (54.66%), Query Frame = 3
Query: 270 QVPVKSA----NEQKKSEI---------KHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEF--------QANMDVKLLAYCKQH 1139
QVPV+S N+QKKS + +P + + +P R Y++ + E E Y++D D +W+E+ N +RK G+ +S + E + + LE+ + S R + DE++ C +C +G D N ++FC+ C + VHQ CYG+P +P G W+CRHC +CP+ +QC+ CPN+GGA+K+ +D+D+W H++CA+W+PEVGF + +EPI + IP ARW L C+LCK GA IQC + C AFHV+CA Q L MK E + VK AYC H
Sbjct: 83 QVPVRSVRLKNNQQKKSAALTTSHSASSGSLLEPKVRQVEYNLPVVPKRPAAFYKYTERTGEELDE--EVEYDMDEEDCAWLELINEKRKSEGVSPVSHHLFEFLMDRLEKESL--LTSHDRSDPQSLV--DEDAVCCICMDGDGADSNVILFCDSCNIAVHQECYGVPYIPEGQWLCRHCLQCPSRPAQCLFCPNQGGALKR--TDDDRWGHVACALWVPEVGFSDTVFIEPIDGVRNIPPARWKLTCYLCKAKGAGACIQCDKINCYTAFHVSCAQQAGLYMKMEAVKEVAPSGASTYSVKKTAYCCSH 385
BLAST of Protein Jade-1 vs. Planmine SMEST
Match: SMESG000051958.1 (SMESG000051958.1) HSP 1 Score: 1399.8 bits (3622), Expect = 0.000e+0 Identity = 746/747 (99.87%), Postives = 747/747 (100.00%), Query Frame = 3
Query: 69 MESHNEIVEKLLNEYETEINYTKSKDSHAEVFDKHPITAMSEVDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMIATNNPVSIVSNIPKEQLLISSKLKTDIYEKLKEPIFICHYLMPNIQDLLLYSMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXISLAXXXXXXXXXXXXXXXXXXTKVEEKIFPPAPKKVCVKICNEENQLICRKSLPSRNIFDMADKM 2309
MESHNEIVEKLLNEYETEINYTKSKDSHAEVFDKHPITAMSE+DPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIQKQKEFEQKFSKFVNAKELSETLHEFPKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMIATNNPVSIVSNIPKEQLLISSKLKTDIYEKLKEPIFICHYLMPNIQDLLLYSMKQQQQEDNNEDGEQEEEDDEDKLKKQENEISLANELPEDSDSSSNSILDISTKVEEKIFPPAPKKVCVKICNEENQLICRKSLPSRNIFDMADKM
Sbjct: 1 MESHNEIVEKLLNEYETEINYTKSKDSHAEVFDKHPITAMSEMDPNSTDRVLIITDSWTPDWCRDGVQVPVKSANEQKKSEIKHIGKPAAKTENFIMPEKLIRHTRKYEFLPEKHCHMPEMHEFLYEIDPIDSSWIEISNVERKCLGLQLISETMLEIIFEILERLCYKRIQSKVREAETEFLEHDENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIQKQKEFEQKFSKFVNAKELSETLHEFPKQLIDPLKSIPSDIKDKIFTYWTLKRTSNHFQCLIKPPSIWSEENLKQRINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLFELMSKISSLQLEQLKNSRLNSILKDDPSLAGNWGFISTVHLDDNVYVNPDNLLDVNLEYVMNKMNLTKPESLEPHKQLLEYNVFDEKPMKTVRKYTRKPQMIATNNPVSIVSNIPKEQLLISSKLKTDIYEKLKEPIFICHYLMPNIQDLLLYSMKQQQQEDNNEDGEQEEEDDEDKLKKQENEISLANELPEDSDSSSNSILDISTKVEEKIFPPAPKKVCVKICNEENQLICRKSLPSRNIFDMADKM 747
BLAST of Protein Jade-1 vs. Planmine SMEST
Match: SMESG000047551.1 (SMESG000047551.1) HSP 1 Score: 189.119 bits (479), Expect = 2.885e-49 Identity = 111/331 (33.53%), Postives = 170/331 (51.36%), Query Frame = 3
Query: 624 DENSKCDVCQSPEGEDGNELVFCEDCFVCVHQACYGIPELPSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMK----QEFQANMDVKLLAYCKQHSKKYQEPNTSESSVNMGPRDIKELRIXXXXXXXXXXXXXVNAKELSETLHEFPKQLIDPLKSIPSDIK--------DKIFTYWTLKRTSNHFQCLIKP-PSIWSEENL------KQRINNRSIMNAFCKIRFGLDRARLVVDMMVRREKKKAHLF 1559
DE++ CDVC ++ N ++FC+ C + VHQ CYG+P +P G W+CR C P+ C LCPN+GGA KQ +++++WAH+ C +WIPE+ F N+ +EPI + I ARW L C+LCK N GA IQC + C AFHVTCA Q L MK ++ ++ A+C HS + S ++ + K+++ + K +N + FP + LK I +I ++I YW +KR L++ + S+ NL K S + + +IR L++ARL+ ++ +REK K LF
Sbjct: 332 DEDAVCDVCLDGTCDNSNVILFCDVCNLAVHQECYGVPYVPEGQWLCRKCLHSPSHPVDCCLCPNKGGAFKQ--TNDNRWAHVVCGLWIPEIMFANLIFLEPIENVEKIEAARWRLACYLCKQKNVGACIQCHKSNCYTAFHVTCAQQAGLYMKIEQSEKISGPAGIRKSAFCDVHSPSGYKAGVSRGMYANSDEELTSEKPGKRQKKLKDVRKLLNKRRNYTAPISFPVIPPEKLKEITDNIDVRNKEEFMNRIHAYWKMKREYRSGVPLLRRLVASSSKSNLALLSIDKDSSEMISNLKFWQQIRQDLEKARLLSELSRKREKIKRELF 660
BLAST of Protein Jade-1 vs. Planmine SMEST
Match: SMESG000057438.1 (SMESG000057438.1) HSP 1 Score: 108.997 bits (271), Expect = 4.356e-24 Identity = 61/181 (33.70%), Postives = 101/181 (55.80%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFCE--DCFVCVHQACYGIPELPSGSWICRHC-DKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSN------TGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQ 1154
C VC E + N +V C+ +C VH+ACYGI ++P G+W C+ C + +C LCP+R GA+K +++ W H+ CA+++P F + + +E I+ ++ + + N C +C+ +N TGA IQC + CK+ FHVTCA Q ++ + + V+ +AYC H K +
Sbjct: 7 CCVCLKEEPFENNPIVSCDGKNCSTTVHKACYGIQQIPDGAWFCQKCISQERTARVRCELCPSRDGALKH--TNKGGWCHIICALFVPGAEFLDTERLESIS-VDKVLTDKLNKMCTICEKNNRLDRATTGACIQCVKSGCKVLFHVTCA-QAQGLLTEIVNSKDSVRYVAYCFAHKHKTK 183
BLAST of Protein Jade-1 vs. Planmine SMEST
Match: SMESG000057438.1 (SMESG000057438.1) HSP 1 Score: 108.612 bits (270), Expect = 5.142e-24 Identity = 61/181 (33.70%), Postives = 101/181 (55.80%), Query Frame = 3
Query: 639 CDVCQSPEGEDGNELVFCE--DCFVCVHQACYGIPELPSGSWICRHC-DKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSN------TGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQ 1154
C VC E + N +V C+ +C VH+ACYGI ++P G+W C+ C + +C LCP+R GA+K +++ W H+ CA+++P F + + +E I+ ++ + + N C +C+ +N TGA IQC + CK+ FHVTCA Q ++ + + V+ +AYC H K +
Sbjct: 7 CCVCLKEEPFENNPIVSCDGKNCSTTVHKACYGIQQIPDGAWFCQKCISQERTARVRCELCPSRDGALKH--TNKGGWCHIICALFVPGAEFLDTERLESIS-VDKVLTDKLNKMCTICEKNNRLDRATTGACIQCVKSGCKVLFHVTCA-QAQGLLTEIVNSKDSVRYVAYCFAHKHKTK 183
BLAST of Protein Jade-1 vs. Planmine SMEST
Match: SMESG000036910.1 (SMESG000036910.1) HSP 1 Score: 77.0258 bits (188), Expect = 4.054e-14 Identity = 50/179 (27.93%), Postives = 83/179 (46.37%), Query Frame = 3
Query: 690 CEDCFVCVHQACYGIPEL----------PSGSWICRHCDKCPNESSQCILCPNRGGAMKQLESDEDKWAHLSCAVWIPEVGFGNIDLMEPITRLNTIPQARWNLRCHLCKTSNTGAPIQCSEKKCKMAFHVTCAIQNSLVMKQEFQANMDVKLLAYCKQHSKKYQEPNT--SESSVNMG 1190
C C + VH CYG E+ P +W C C K N C LC RGGA+K+L + WAH+ C + E+ F DL+ R+ + +C +CK + +C+ C+ + HVTCA ++++++ E ++ C +H Y + T ++SS+ +G
Sbjct: 574 CSHCNLTVHARCYGNVEVDRSLSKGECEPDQNWTCDRCVKF-NPLIHCSLCSVRGGALKKLTNRNSGWAHIVCTLACQEMVFE--DLLHRKPRIRDKSTEYTSNKCSICKGRQSQPICKCAFPDCRSSVHVTCAFFHNVLIESETYPHL---FFVICMKHPSYYAKQPTPNAQSSITVG 746 The following BLAST results are available for this feature:
BLAST of Protein Jade-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein Jade-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein Jade-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Protein Jade-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein Jade-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein Jade-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032893 ID=SMED30032893|Name=Protein Jade-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2510bpback to top protein sequence of SMED30032893-orf-1 >SMED30032893-orf-1 ID=SMED30032893-orf-1|Name=SMED30032893-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=748bp MESHNEIVEKLLNEYETEINYTKSKDSHAEVFDKHPITAMSEVDPNSTDRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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