Kinase

Overview
NameKinase
Smed IDSMED30032881
Length (bp)2325
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Kinase (SMED30032881) t-SNE clustered cells

Violin plots show distribution of expression levels for Kinase (SMED30032881) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kinase (SMED30032881) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kinase (SMED30032881) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032881

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 14

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30032881h1SMcG0010329 PL05006A2G05smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30032881h1SMcG0010329 Contig55348uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032881h1SMcG0010329 Contig55348newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032881h1SMcG0010329 Contig29775uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032881h1SMcG0010329 Contig29775newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30032881h1SMcG0010329 dd_Smed_v4_8300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30032881h1SMcG0010329 dd_Smed_v4_8300_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30032881h1SMcG0010329 dd_Smed_v4_8479_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30032881h1SMcG0010329 dd_Smed_v4_8479_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30032881h1SMcG0010329 dd_Smed_v4_8479_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032881h1SMcG0018485 Contig55348uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032881h1SMcG0018485 Contig55348newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
tail regionSMED30032881h1SMcG0010329 dd_Smed_v6_8479_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
intestinal phagocyteSMED30032881h1SMcG0010329 dd_Smed_v6_8479_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Kinase vs. Ensembl Human
Match: CDKL3 (cyclin dependent kinase like 3 [Source:HGNC Symbol;Acc:HGNC:15483])

HSP 1 Score: 98.9821 bits (245), Expect = 3.439e-21
Identity = 77/227 (33.92%), Postives = 116/227 (51.10%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV--PEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  N  GQ V  + F   PE+SV +I +  EIK+L+ F  +  L++        KKI   F   + ++ ++++             +    + K  ++IL  +  LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+  K  S     DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKN-TGQIVAIKIFYERPEQSVNKIAM-REIKFLKQF-HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIY---TDYVATRWYRAPELV-LKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Human
Match: CDKL3 (cyclin dependent kinase like 3 [Source:HGNC Symbol;Acc:HGNC:15483])

HSP 1 Score: 99.3673 bits (246), Expect = 6.297e-21
Identity = 78/232 (33.62%), Postives = 117/232 (50.43%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV--PEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  N  GQ V  + F   PE+SV +I +  EIK+L+ F  +  L++        KKI   F   + ++ ++++             +    + K  ++IL  +  LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKN-TGQIVAIKIFYERPEQSVNKIAM-REIKFLKQF-HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Human
Match: CDKL3 (cyclin dependent kinase like 3 [Source:HGNC Symbol;Acc:HGNC:15483])

HSP 1 Score: 98.9821 bits (245), Expect = 7.302e-21
Identity = 78/232 (33.62%), Postives = 117/232 (50.43%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV--PEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  N  GQ V  + F   PE+SV +I +  EIK+L+ F  +  L++        KKI   F   + ++ ++++             +    + K  ++IL  +  LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKN-TGQIVAIKIFYERPEQSVNKIAM-REIKFLKQF-HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Human
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 82.8037 bits (203), Expect = 8.821e-17
Identity = 62/211 (29.38%), Postives = 111/211 (52.61%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPE--ESVREI-NINEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRV----PLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K  ++  IG GS+G VY+ +   +  Q V  +F +P+   S +E+ N+  EI+ +      RGL   N  I      FE   +  +         F++      + E+++  +A +++  L  LH  +ILH D+KP+NILL K G   LCD+G ++ + + T +    + + GT  Y++PEL+  +P  D T +D+WS+G ++ E+  G
Sbjct:    1 MEKYHVLEMIGEGSFGRVYKGRR-KYSAQVVALKF-IPKLGRSEKELRNLQREIEIM------RGLRHPN--IVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVL---TSIKGTPLYMSPELVEERPY-DHT-ADLWSVGCILYELAVG 196
[Close]
BLAST of Kinase vs. Ensembl Human
Match: CDKL4 (cyclin dependent kinase like 4 [Source:HGNC Symbol;Acc:HGNC:19287])

HSP 1 Score: 83.5741 bits (205), Expect = 1.023e-16
Identity = 61/213 (28.64%), Postives = 106/213 (49.77%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE--------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++K + + K G GSYG V++C+     GQ V  + FV  E        ++REI + +++K+    P    L+   ++      +FE   D+ +   +  NPN     +++  I  + ++ L  L   H    +H DIKPENIL+ K G   +CD+G ++++    +     +D   T  Y APEL+ G  Q   +  DIW++G V  E++ G+
Sbjct:    1 MEKYEKLAKTGEGSYGVVFKCRNKT-SGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH----PNLVNLIEVFRRKRKMHLVFEYC-DHTLLNELERNPNG----VADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAY----TDYVATRWYRAPELLVGDTQYG-SSVDIWAIGCVFAELLTGQ 198
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: cdkl-1 (Cyclin-dependent kinase-like 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2H1])

HSP 1 Score: 87.4261 bits (215), Expect = 3.319e-18
Identity = 63/215 (29.30%), Postives = 114/215 (53.02%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSY---NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            + K   ++K+G GSYG VY+CK  +      IK+F   E+       ++REI + +++K+  L     GL+     N+K+   F L ++++ ++++     NP+     +++  I K+ Y++L  LK  H  K +H D+KPENI L ++ +  L D+G +++I +        +D   T  Y +PEL+ G  Q      DIW++G V  E++ G+
Sbjct:    1 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLV----GLIEVFKRNRKLHLVFELCDRTVLHELE----KNPHG----VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMY----TDYVATRWYRSPELLVGDVQYG-PPVDIWAVGCVYAELLTGE 198
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: cdkl-1 (Cyclin-dependent kinase-like 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2H1])

HSP 1 Score: 87.4261 bits (215), Expect = 4.473e-18
Identity = 63/215 (29.30%), Postives = 114/215 (53.02%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSY---NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            + K   ++K+G GSYG VY+CK  +      IK+F   E+       ++REI + +++K+  L     GL+     N+K+   F L ++++ ++++     NP+     +++  I K+ Y++L  LK  H  K +H D+KPENI L ++ +  L D+G +++I +        +D   T  Y +PEL+ G  Q      DIW++G V  E++ G+
Sbjct:   31 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLV----GLIEVFKRNRKLHLVFELCDRTVLHELE----KNPHG----VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMY----TDYVATRWYRSPELLVGDVQYG-PPVDIWAVGCVYAELLTGE 228
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: cdkl-1 (Cyclin-dependent kinase-like 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2H1])

HSP 1 Score: 87.0409 bits (214), Expect = 1.092e-17
Identity = 63/215 (29.30%), Postives = 114/215 (53.02%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSY---NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            + K   ++K+G GSYG VY+CK  +      IK+F   E+       ++REI + +++K+  L     GL+     N+K+   F L ++++ ++++     NP+     +++  I K+ Y++L  LK  H  K +H D+KPENI L ++ +  L D+G +++I +        +D   T  Y +PEL+ G  Q      DIW++G V  E++ G+
Sbjct:  132 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLV----GLIEVFKRNRKLHLVFELCDRTVLHELE----KNPHG----VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTTEMY----TDYVATRWYRSPELLVGDVQYG-PPVDIWAVGCVYAELLTGE 329
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8])

HSP 1 Score: 80.1073 bits (196), Expect = 1.271e-15
Identity = 70/212 (33.02%), Postives = 106/212 (50.00%), Query Frame = 1 
Query: 1393 MITKIGNGSYGEVYQCKEANFDGQFVIKRFFVP---EESVREININEE------IKYLELFPKYRGL---MSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++ K+G GSYG V++           IK+  V    +E ++EI+I ++      +KY   + K+  L   M Y    C A S+ +          +R+    R PL SE EI  +  + L  L+ LH  K +H DIK  NILL+  G A L D+G +  +   T     ++ + GT  ++APE+I  +     TK+DIWSLGI  IEM EG+
Sbjct:   37 IVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEY----CGAGSISD---------IMRAR---RKPL-SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQL---TDTMAKRNTVIGTPFWMAPEVI--EEIGYDTKADIWSLGITAIEMAEGR 226
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31])

HSP 1 Score: 80.8777 bits (198), Expect = 1.294e-15
Identity = 70/212 (33.02%), Postives = 106/212 (50.00%), Query Frame = 1 
Query: 1393 MITKIGNGSYGEVYQCKEANFDGQFVIKRFFVP---EESVREININEE------IKYLELFPKYRGL---MSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++ K+G GSYG V++           IK+  V    +E ++EI+I ++      +KY   + K+  L   M Y    C A S+ +          +R+    R PL SE EI  +  + L  L+ LH  K +H DIK  NILL+  G A L D+G +  +   T     ++ + GT  ++APE+I  +     TK+DIWSLGI  IEM EG+
Sbjct:   37 IVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEY----CGAGSISD---------IMRAR---RKPL-SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQL---TDTMAKRNTVIGTPFWMAPEVI--EEIGYDTKADIWSLGITAIEMAEGR 226
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: CG7236 (gene:FBgn0031730 transcript:FBtr0302950)

HSP 1 Score: 92.4337 bits (228), Expect = 1.762e-19
Identity = 63/234 (26.92%), Postives = 118/234 (50.43%), Query Frame = 1 
Query: 1330 IRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            I+  + +++  +   ++ + + ++++G GSYG VY+C++        +KRF   E+       ++REI + + +K+      LE+F + R L          F   E ++ ++++   +  P        E+   ++ Y+ L+ +   HK   LH DIKPENILL   G+  LCD+G ++++    S   N +D   T  Y APEL+ G  Q   T  D+W++G +  E++ G+
Sbjct:   28 IKRGQCLSLRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLH-------LVFEFCELTVLHELERHPQGCP--------EHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQYG-TPVDVWAIGCLFAELVRGE 241
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: CG7236 (gene:FBgn0031730 transcript:FBtr0343388)

HSP 1 Score: 92.0485 bits (227), Expect = 2.244e-19
Identity = 61/219 (27.85%), Postives = 112/219 (51.14%), Query Frame = 1 
Query: 1375 RLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++ + + ++++G GSYG VY+C++        +KRF   E+       ++REI + + +K+      LE+F + R       ++   F   E ++ ++++   +  P        E+   ++ Y+ L+ +   HK   LH DIKPENILL   G+  LCD+G ++++    S   N +D   T  Y APEL+ G  Q   T  D+W++G +  E++ G+
Sbjct:   20 KMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKR-------RLHLVFEFCELTVLHELERHPQGCP--------EHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQYG-TPVDVWAIGCLFAELVRGE 218
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: CG7236 (gene:FBgn0031730 transcript:FBtr0343387)

HSP 1 Score: 92.0485 bits (227), Expect = 2.497e-19
Identity = 61/219 (27.85%), Postives = 112/219 (51.14%), Query Frame = 1 
Query: 1375 RLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++ + + ++++G GSYG VY+C++        +KRF   E+       ++REI + + +K+      LE+F + R       ++   F   E ++ ++++   +  P        E+   ++ Y+ L+ +   HK   LH DIKPENILL   G+  LCD+G ++++    S   N +D   T  Y APEL+ G  Q   T  D+W++G +  E++ G+
Sbjct:   46 KMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKR-------RLHLVFEFCELTVLHELERHPQGCP--------EHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQYG-TPVDVWAIGCLFAELVRGE 244
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: CG7236 (gene:FBgn0031730 transcript:FBtr0343389)

HSP 1 Score: 91.6633 bits (226), Expect = 3.109e-19
Identity = 61/219 (27.85%), Postives = 112/219 (51.14%), Query Frame = 1 
Query: 1375 RLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++ + + ++++G GSYG VY+C++        +KRF   E+       ++REI + + +K+      LE+F + R       ++   F   E ++ ++++   +  P        E+   ++ Y+ L+ +   HK   LH DIKPENILL   G+  LCD+G ++++    S   N +D   T  Y APEL+ G  Q   T  D+W++G +  E++ G+
Sbjct:   29 KMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKR-------RLHLVFEFCELTVLHELERHPQGCP--------EHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQYG-TPVDVWAIGCLFAELVRGE 227
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: png (gene:FBgn0000826 transcript:FBtr0070234)

HSP 1 Score: 79.337 bits (194), Expect = 8.329e-16
Identity = 55/210 (26.19%), Postives = 105/210 (50.00%), Query Frame = 1 
Query: 1384 KEQMITKIGNGSYGEVYQCKEANFDGQ----FVIKRFFVPEESVREININEEIKYLELFPKYRGLMSYNKKICAAFSL---FEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            K + +  +G G++G V+ C +    GQ      +KR  V         I EE+  +    ++  ++ + +    A ++    E   +  ++  I+  P+     +++  ++    ++++ L+ LH   ++H DIKPEN+LLD + R  + D+G + V    T LQ       GT  Y+APE ++ + + D  KSD+WSLG+V+ E+  G+
Sbjct:    7 KLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQL-RHPHIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPS-GTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAGM----GTPMYMAPEAMSSQGKVD-FKSDVWSLGLVLYELCLGR 209
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: nek1 (NIMA-related kinase 1 [Source:ZFIN;Acc:ZDB-GENE-040730-1])

HSP 1 Score: 82.8037 bits (203), Expect = 6.171e-17
Identity = 67/214 (31.31%), Postives = 103/214 (48.13%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVP-------EESVREININEE------IKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            + K + + KIG GS+G+    K      Q+VIK   +        +ES +E+ +         ++Y E F +  G +      C    LF+K ++N+           R  L  E +I+    +I + LK +H  KILH DIK +NI L K G   L D+G ++V+ S   L        GT  Y++PE+   KP ++  KSDIW+LG V+ EM
Sbjct:    1 MDKYERLKKIGEGSFGKAILVKSRTDGRQYVIKEIGISRMSNKERQESRKEVAVLANMSHPNIVQYKESFEE-SGCLYIVMDYCEGGDLFKK-INNQ-----------RGSLFPEEQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVEL---ARTCIGTPYYLSPEICENKPYNN--KSDIWALGCVLYEM 196
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: cdkl1 (cyclin-dependent kinase-like 1 (CDC2-related kinase) [Source:NCBI gene;Acc:445316])

HSP 1 Score: 83.1889 bits (204), Expect = 1.148e-16
Identity = 59/214 (27.57%), Postives = 104/214 (48.60%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSY---NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + I+KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K+    P    LM      +K+   F   + ++ N++    R  P        E+ +  + ++ L  +   HK   +H D+KPENIL+ K     LCD+G ++++          +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:    1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKH----PNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVP--------EHMVKSIIWQTLQAVNFCHKQNCIHRDVKPENILITKHQVIKLCDFGFARILTGPCDYY---TDYVATRWYRAPELLVGDTQYG-PPVDVWAVGCVFAELLSG 198
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246])

HSP 1 Score: 84.7297 bits (208), Expect = 2.461e-16
Identity = 68/211 (32.23%), Postives = 104/211 (49.29%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVR-EININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLI--------SENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDK-SGRATLCDYGCSKVI-----CSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            +G G+YG VY  ++ +   +  IK   +PE   R    ++EEI  L  + K+R ++ Y         L   S D  IKI +   P   +  +         E  II    +IL  ++ LH+ +I+H DIK +N+L++  SG   + D+G SK +     C++T          GTL Y+APE+I+  P+     +DIWSLG  IIEM  GK
Sbjct:  658 LGRGTYGVVYAGRDLSNQVRIAIKE--IPERDSRYSQPLHEEIA-LHKYLKHRNIVQY---------LGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGIRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTET--------FTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGK 848
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246])

HSP 1 Score: 84.7297 bits (208), Expect = 2.461e-16
Identity = 68/211 (32.23%), Postives = 104/211 (49.29%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVR-EININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLI--------SENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDK-SGRATLCDYGCSKVI-----CSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            +G G+YG VY  ++ +   +  IK   +PE   R    ++EEI  L  + K+R ++ Y         L   S D  IKI +   P   +  +         E  II    +IL  ++ LH+ +I+H DIK +N+L++  SG   + D+G SK +     C++T          GTL Y+APE+I+  P+     +DIWSLG  IIEM  GK
Sbjct:  658 LGRGTYGVVYAGRDLSNQVRIAIKE--IPERDSRYSQPLHEEIA-LHKYLKHRNIVQY---------LGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGIRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTET--------FTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGK 848
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246])

HSP 1 Score: 84.7297 bits (208), Expect = 2.529e-16
Identity = 68/211 (32.23%), Postives = 104/211 (49.29%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVR-EININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLI--------SENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDK-SGRATLCDYGCSKVI-----CSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            +G G+YG VY  ++ +   +  IK   +PE   R    ++EEI  L  + K+R ++ Y         L   S D  IKI +   P   +  +         E  II    +IL  ++ LH+ +I+H DIK +N+L++  SG   + D+G SK +     C++T          GTL Y+APE+I+  P+     +DIWSLG  IIEM  GK
Sbjct:  629 LGRGTYGVVYAGRDLSNQVRIAIKE--IPERDSRYSQPLHEEIA-LHKYLKHRNIVQY---------LGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGIRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTET--------FTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGK 819
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: CDKL1 (cyclin dependent kinase like 1 [Source:NCBI gene;Acc:100496578])

HSP 1 Score: 81.6481 bits (200), Expect = 6.001e-16
Identity = 58/217 (26.73%), Postives = 106/217 (48.85%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + I KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K+      LE+F + R       K+   F   + ++ +++    R  P        E+ +  + ++ L  +   HK   +H D+KPENIL+ +     LCD+G ++++   +      +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:    1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKR-------KLHLVFEYCDHTVLHELDKYPRGVP--------EHLVKSITWQTLQAVNFCHKHHCIHRDVKPENILITRHSVIKLCDFGFARLLTGPSDYY---TDYVATRWYRAPELLVGDTQYG-PPVDVWAIGCVFAELLSG 198
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: ephb1 (EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626])

HSP 1 Score: 84.3445 bits (207), Expect = 6.267e-16
Identity = 73/219 (33.33%), Postives = 106/219 (48.40%), Query Frame = 1 
Query: 1384 KEQMITKIGNGSYGEVYQCKEANFDGQFVIKRF-FVP------EESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKL-AYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPG----TLG---YIAPELIN-GKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            K Q   KIG G YG+VY C   +      +K   F P      +E+  E+ I E IK+  L  +Y G+  + +++   +   E   +  ++   R        L  +  +I+L   +I I + VLH+  I+H DIK  NI L  SG   L D+GCS        L+ N   +PG    TLG   Y+APE+I   K +     +DIWSLG V+IEM+ GK
Sbjct: 1275 KWQRGNKIGEGQYGKVYTCISIDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLV-RYFGVELHREEM---YIFMEYCDEGTLEEVSR--------LGLQEHVIRLYTKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCS------VKLKNNAQTMPGEVNSTLGTAAYMAPEVITQAKGEGHGRAADIWSLGCVLIEMVTGK 1475
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: CDKL1 (cyclin dependent kinase like 1 [Source:NCBI gene;Acc:100496578])

HSP 1 Score: 81.6481 bits (200), Expect = 6.514e-16
Identity = 58/217 (26.73%), Postives = 106/217 (48.85%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + I KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K+      LE+F + R       K+   F   + ++ +++    R  P        E+ +  + ++ L  +   HK   +H D+KPENIL+ +     LCD+G ++++   +      +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:    1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKR-------KLHLVFEYCDHTVLHELDKYPRGVP--------EHLVKSITWQTLQAVNFCHKHHCIHRDVKPENILITRHSVIKLCDFGFARLLTGPSDYY---TDYVATRWYRAPELLVGDTQYG-PPVDVWAIGCVFAELLSG 198
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: ephb1 (EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626])

HSP 1 Score: 83.9593 bits (206), Expect = 7.061e-16
Identity = 73/219 (33.33%), Postives = 106/219 (48.40%), Query Frame = 1 
Query: 1384 KEQMITKIGNGSYGEVYQCKEANFDGQFVIKRF-FVP------EESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKL-AYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPG----TLG---YIAPELIN-GKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            K Q   KIG G YG+VY C   +      +K   F P      +E+  E+ I E IK+  L  +Y G+  + +++   +   E   +  ++   R        L  +  +I+L   +I I + VLH+  I+H DIK  NI L  SG   L D+GCS        L+ N   +PG    TLG   Y+APE+I   K +     +DIWSLG V+IEM+ GK
Sbjct: 1274 KWQRGNKIGEGQYGKVYTCISIDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLV-RYFGVELHREEM---YIFMEYCDEGTLEEVSR--------LGLQEHVIRLYTKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCS------VKLKNNAQTMPGEVNSTLGTAAYMAPEVITQAKGEGHGRAADIWSLGCVLIEMVTGK 1474
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: ephb1 (EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626])

HSP 1 Score: 83.9593 bits (206), Expect = 7.084e-16
Identity = 73/219 (33.33%), Postives = 106/219 (48.40%), Query Frame = 1 
Query: 1384 KEQMITKIGNGSYGEVYQCKEANFDGQFVIKRF-FVP------EESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKL-AYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPG----TLG---YIAPELIN-GKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            K Q   KIG G YG+VY C   +      +K   F P      +E+  E+ I E IK+  L  +Y G+  + +++   +   E   +  ++   R        L  +  +I+L   +I I + VLH+  I+H DIK  NI L  SG   L D+GCS        L+ N   +PG    TLG   Y+APE+I   K +     +DIWSLG V+IEM+ GK
Sbjct: 1127 KWQRGNKIGEGQYGKVYTCISIDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLV-RYFGVELHREEM---YIFMEYCDEGTLEEVSR--------LGLQEHVIRLYTKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCS------VKLKNNAQTMPGEVNSTLGTAAYMAPEVITQAKGEGHGRAADIWSLGCVLIEMVTGK 1327
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 98.5969 bits (244), Expect = 1.032e-21
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 98.5969 bits (244), Expect = 1.032e-21
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 97.8265 bits (242), Expect = 6.027e-21
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 97.8265 bits (242), Expect = 1.169e-20
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Cdkl3 (cyclin-dependent kinase-like 3 [Source:MGI Symbol;Acc:MGI:2388268])

HSP 1 Score: 97.8265 bits (242), Expect = 1.169e-20
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q4R8T9|CDKL3_MACFA (Cyclin-dependent kinase-like 3 OS=Macaca fascicularis OX=9541 GN=CDKL3 PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 3.390e-20
Identity = 78/232 (33.62%), Postives = 117/232 (50.43%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV--PEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  N  GQ V  + F   PE+SV +I +  EIK+L+ F  +  L++        KKI   F   + ++ ++++             +    + K  ++IL  +  LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKN-TGQIVAIKIFYERPEQSVNKIAM-REIKFLKQF-HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q8IVW4|CDKL3_HUMAN (Cyclin-dependent kinase-like 3 OS=Homo sapiens OX=9606 GN=CDKL3 PE=1 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 3.507e-20
Identity = 78/232 (33.62%), Postives = 117/232 (50.43%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV--PEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  N  GQ V  + F   PE+SV +I +  EIK+L+ F  +  L++        KKI   F   + ++ ++++             +    + K  ++IL  +  LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKN-TGQIVAIKIFYERPEQSVNKIAM-REIKFLKQF-HHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q9JM01|CDKL3_RAT (Cyclin-dependent kinase-like 3 OS=Rattus norvegicus OX=10116 GN=Cdkl3 PE=1 SV=2)

HSP 1 Score: 97.8265 bits (242), Expect = 8.107e-20
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTTYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q8BLF2|CDKL3_MOUSE (Cyclin-dependent kinase-like 3 OS=Mus musculus OX=10090 GN=Cdkl3 PE=2 SV=2)

HSP 1 Score: 97.4413 bits (241), Expect = 1.160e-19
Identity = 76/231 (32.90%), Postives = 117/231 (50.65%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLK 2034
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LK
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLK 216
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|P32490|MKK1_YEAST (MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK1 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.650e-17
Identity = 66/204 (32.35%), Postives = 104/204 (50.98%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFV----PE---ESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKL 1995
            +G G+ G V +CK  N    F +K        PE   +  RE+  N   +  E   +Y G+ + ++   ++  +  + M  +    I  N   R   ISE  + K+A  +L  L  LH+ K++H DIKP+NILL+++G+  LCD+G S    +  +     +   GT  Y+APE I G+P S    SD+WSLG+ I+E+  GK 
Sbjct:  227 LGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQS-EYIVRYYGMFTDDEN--SSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLA-----TTFTGTSFYMAPERIQGQPYS--VTSDVWSLGLTILEVANGKF 420
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A3Q0CGF3 (cyclin-dependent kinase-like 3 isoform X3 OS=Mesocricetus auratus OX=10036 GN=Cdkl3 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.131e-19
Identity = 87/268 (32.46%), Postives = 132/268 (49.25%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFF-VPEESVREININEEIKYLELFPKYRGLMSY------NKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELI-----NGKPQSDKTKSDIWSLGIVIIEMMEGK----LSSDIKFSHKINLKA-LQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAF 2142
            + + K+G GSYG V +CK  +      IK F+  PE+SV +I    EIK+L+ F ++  L++        KKI   F   + ++ ++++             +    + K  ++IL  ++ LH   I+H DIKPENIL+ +SG   LCD+G ++ + +   +    +D   T  Y APEL+      GKP       DIW+LG +IIEM  G      SSD+   HKI LKA LQ                +P ER+S+ +LL  D F
Sbjct:    5 ETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKI-ATREIKFLKQF-RHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG--------LESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVY---TDYVATRWYRAPELVLKDTSYGKP------VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKACLQI---------------DPAERISSTDLLHHDYF 238
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A4P9YQ68 (Kinase-like protein OS=Rozella allomycis (strain CSF55) OX=988480 GN=ROZALSC1DRAFT_11703 PE=3 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 1.487e-19
Identity = 84/241 (34.85%), Postives = 127/241 (52.70%), Query Frame = 1 
Query: 1306 DERDLNIPIRITEHMTI---HFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPE-ESVREIN--INEE---IKYLEL--FPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIK-LAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            D   LN+  +++  M++   HF+  +R +  Q+   IG GS+G VY C + +      IK    P+  SV E N  + EE   I+YL+     +Y GL  Y+K       L E      ++  IR+ P      I+E  IIK ++ +IL  L+ LH   I+H DIKP+NIL+D  G   L D+G +K++ S+ ++    + L GT  Y+APE+I G   +  TK DIWS G  ++EM  GK
Sbjct:   60 DHEFLNLKNKVSCCMSLLISHFQRRERFRY-QIRNCIGTGSFGTVYDCIDLDTGELMAIKEIRFPDVNSVVETNQQVKEELDVIQYLQHSNIVEYYGL-EYHKD--HVHILMEYCSGGSLENLIRNEP------ITEVSIIKQISVQILEGLRYLHSKDIIHRDIKPDNILIDSKGVVKLVDFGAAKIVKSKKTVN-GANTLIGTPAYMAPEIIIGDEVT--TKVDIWSFGCTVLEMATGK 287
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A182M7R0 (Protein kinase domain-containing protein OS=Anopheles culicifacies OX=139723 PE=3 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 2.803e-19
Identity = 66/218 (30.28%), Postives = 110/218 (50.46%), Query Frame = 1 
Query: 1375 RLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            R+ + + ++++G GSYG VY+C++        +KRF   E+       ++REI + + +K+      LE+F + R L     + C    L E     ++ +  R N +  V    +N   ++ Y+ +  +   HK   LH DIKPENILL   G+  LCD+G ++++    S   N +D   T  Y APEL+ G  Q   T  D+W++G V  E++ G
Sbjct:   65 RMDRYEKLSRLGEGSYGVVYKCRDRETGSLVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVCLLEVFRRKRRL-HLVFEFCEHTVLHELERHPEVGVNARQNTDLHVIGCPDNLTKQITYQTIQGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQYG-TPVDVWAIGCVFAELVRG 276
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A1W0WA82 (Cyclin-dependent kinase-like 1 OS=Hypsibius dujardini OX=232323 GN=BV898_13605 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 8.914e-19
Identity = 81/283 (28.62%), Postives = 136/283 (48.06%), Query Frame = 1 
Query: 1396 ITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKY------LELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIV---------------------IIEMMEGKLSSDIKFSHKINLKALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAF 2142
            ITKIG GSYG V++C+++  D    +KRF   +E       + REI I +++++      LE+F +        K++   F   ++++ ++++ T      F +P   E +  ++  E+L  ++ +H+ + LH DIKPENILL  SG+  LCD+G ++ I    +     +D   T  Y APEL+  +P    +  DIW++G V                     +IE M G  +     +    L+     S   + +L + L T+P ER +AK LLQ   F
Sbjct:   29 ITKIGQGSYGTVFKCRDSQTDTIVAVKRFLETDEQSHIRKIAYREIRILKKLRHPHIVTLLEVFRR-------RKRLHLVFEYCDRTLLDELQRT-----KFGLP---EKDAQRVIAELLQAVEAVHQHRCLHRDIKPENILLTTSGQVKLCDFGFARSIAETNTENDYYTDYVATRWYRAPELLTDRPVYG-SGVDIWAVGCVFFECLTRVPLLPGTSDIDQRYLIEAMFGDRTEAKSPTLTDKLRRYGSTSSDAQSLLTQMLRTDPSERPTAKSLLQESYF 295
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A0L8H3E8 (Protein kinase domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22023492mg PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.083e-18
Identity = 62/212 (29.25%), Postives = 109/212 (51.42%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            + K   I KIG GSYG VY+C+  +      IK+F   E+       ++REI + +++K+  L      +    K++   F   + ++ N+++     NP+     ++EN++ K+ Y+ L  +   H+ K +H D+KPENIL++K G   LCD+G ++V+          +D   T  Y  PEL+ G  Q      D+W++G V  E++ G+
Sbjct:    1 MDKYDKIAKIGEGSYGVVYKCRNKDTGQLVAIKKFVESEDDYLIKKIAMREIRMLKQLKHQNLVNLIE-VFRRKKRLHLVFEYVDHTVLNELE----KNPHG----VAENQVKKIIYQTLKAVNFCHQHKCIHRDVKPENILVNKQGHVKLCDFGFARVLSPGDEY----TDYVATRWYRGPELLVGDTQYG-PPVDVWAIGCVFAELLTGQ 198
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000033332.1 (cyclin-dependent kinase-like 1 [Source:NCBI gene;Acc:103024925])

HSP 1 Score: 89.3521 bits (220), Expect = 9.018e-19
Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + + KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K++ L      +    +++   F   E+++ N++    +  P        E ++  + ++ L  +   HK   +H D+KPENILL K+G   LCD+G ++++   T    + +D   T  Y APEL+ G  Q      D+W+LG V  E++ G
Sbjct:    1 MEKYEKLAKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHVNLV-NLLEVFRRKRRLHLVFEFCEQTVLNELDKHPKGVP--------EAQLKSIIWQTLQAVNFCHKNNCIHRDVKPENILLTKTGIIKLCDFGFARIL---TGPGDDYTDYVATRWYRAPELLVGDTQYGPA-VDVWALGCVFAELLNG 198
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000057054.1 (cyclin-dependent kinase-like 1 [Source:NCBI gene;Acc:103024925])

HSP 1 Score: 88.9669 bits (219), Expect = 1.280e-18
Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + + KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K++ L      +    +++   F   E+++ N++    +  P        E ++  + ++ L  +   HK   +H D+KPENILL K+G   LCD+G ++++   T    + +D   T  Y APEL+ G  Q      D+W+LG V  E++ G
Sbjct:    1 MEKYEKLAKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHVNLV-NLLEVFRRKRRLHLVFEFCEQTVLNELDKHPKGVP--------EAQLKSIIWQTLQAVNFCHKNNCIHRDVKPENILLTKTGIIKLCDFGFARIL---TGPGDDYTDYVATRWYRAPELLVGDTQYGPA-VDVWALGCVFAELLNG 198
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000052448.1 (cyclin-dependent kinase-like 1 [Source:NCBI gene;Acc:103024925])

HSP 1 Score: 88.9669 bits (219), Expect = 1.280e-18
Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + + KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K++ L      +    +++   F   E+++ N++    +  P        E ++  + ++ L  +   HK   +H D+KPENILL K+G   LCD+G ++++   T    + +D   T  Y APEL+ G  Q      D+W+LG V  E++ G
Sbjct:    1 MEKYEKLAKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHVNLV-NLLEVFRRKRRLHLVFEFCEQTVLNELDKHPKGVP--------EAQLKSIIWQTLQAVNFCHKNNCIHRDVKPENILLTKTGIIKLCDFGFARIL---TGPGDDYTDYVATRWYRAPELLVGDTQYGPA-VDVWALGCVFAELLNG 198
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000004552.2 (cyclin dependent kinase like 2 [Source:NCBI gene;Acc:103039054])

HSP 1 Score: 85.5001 bits (210), Expect = 7.534e-17
Identity = 59/202 (29.21%), Postives = 101/202 (50.00%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            +G GSYG V +C+         +K+F   E+       ++REI + +++++  L      L+   KK    + +FE  ++  +   +   PN   P    N I K  Y+IL  +   H+  I+H DIKPEN+L+ + G   LCD+G ++ + +   +    +D   T  Y APEL+ G  + DK   D+W+ G + +EM+ G
Sbjct:   10 VGEGSYGTVTKCRHRESGRIVAVKKFLESEDDKSVKKIALREIKLLKQLRHENLV----NLLEVWKKKRRWYLVFE-FVERTVLDELEQFPNGLDP----NRIRKYLYQILRAISFCHQHNIIHRDIKPENVLVSQQGVVKLCDFGFARTMAAPGEVY---TDYVATRWYRAPELLVGDSKYDKA-VDVWATGCLFVEMLTG 198
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: cdkl1 (cyclin dependent kinase like 1 [Source:NCBI gene;Acc:103022052])

HSP 1 Score: 83.1889 bits (204), Expect = 9.733e-17
Identity = 58/211 (27.49%), Postives = 102/211 (48.34%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K + I KIG GSYG V++C+  +      IK+F   E+       ++REI + +++K+  L      +    +K+   F   + ++ N++    R  P + V  I+        ++ L  +   HK   +H D+KPENIL+ K     LCD+G ++++          +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:    1 MEKYEKIGKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHCNLV-NLIEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVPEYLVKSIT--------WQTLQAVNFCHKQNCIHRDVKPENILITKHQVIKLCDFGFARILTGPCDYY---TDYVATRWYRAPELLVGDTQYG-PPVDVWAIGCVFAELLSG 198
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96])

HSP 1 Score: 82.8037 bits (203), Expect = 1.258e-16
Identity = 68/209 (32.54%), Postives = 107/209 (51.20%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRF-FVPE--ESVREININE-EIKYL-----ELFPKYRGLMSYNKKICAAFSLFEKSM-DNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSK---VICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            +G G++G VY C +A+   +  +K+  F P   E+ +E+N  E EI+ L     E   +Y G +   ++     S+F + M    IK  +R+        ++EN   K   +IL  +  LH   I+H DIK  NIL D +G   L D+G SK    ICSQ +       + GT  +++PE+ING  +    K+DIWS+G  ++EM+  K
Sbjct:  365 LGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEVNALECEIQLLKNLQHERIVQYFGCLRDPQQ--KTLSIFMEYMPGGSIKDQLRA-----YGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAM---RSVTGTPYWMSPEVING--EGYGRKADIWSVGCTVVEMLTEK 561
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: cdk4 (cyclin-dependent kinase 4 [Source:ZFIN;Acc:ZDB-GENE-060929-974])

HSP 1 Score: 80.1073 bits (196), Expect = 1.524e-16
Identity = 60/218 (27.52%), Postives = 111/218 (50.92%), Query Frame = 1 
Query: 1375 RLKKEQMITKIGNGSYGEVYQCKEANFDGQFV-IKRFFV-------PEESVREININEEIKYLELFPKYRGLMSYNKKICAA--------FSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            RL+ E  I +IG G+YG VY+ ++   +G+FV +K+  V       P  ++RE+ +   ++ LE F     +  ++  +CA          +L  + +D  +   +   P    P +  ++I  + +++L  L  LH  +++H D+KP+NIL+   G+  L D+G +++     S Q+  + +  TL Y APE++     S  T  D+WS+G +  EM
Sbjct:   12 RLQYEP-IAEIGVGAYGTVYKARDLQNEGRFVALKKVRVQTGEEGMPLSTIREVAL---LRQLETFEHPNVVRLFD--VCATSRTDRETRLTLVFEHVDQDLSTYLEKAP---APGLPADKIKDMMHQLLSGLDFLHTHRVVHRDLKPQNILVTSDGQVKLADFGLARIY----SFQMALTSVVVTLWYRAPEVL--LQSSYATTVDLWSVGCIFAEM 214
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 83.1889 bits (204), Expect = 1.590e-16
Identity = 64/211 (30.33%), Postives = 112/211 (53.08%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPE--ESVREI-NINEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRV----PLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            ++K  ++  IG GS+G+VY+ ++  + GQ V  +F +P+   S +E+ N+  EI  +      RGL   N  I      FE   +  +         F++      + E ++ ++A +++  L  LH  +ILH D+KP+NILL K G   LCD+G ++ +   T   +  + + GT  Y++PEL+  KP  D T +D+WS+G ++ E+  G
Sbjct:    1 MEKYHVLEMIGEGSFGKVYKGRK-RYTGQVVALKF-IPKVGRSDKELRNLRREIDIM------RGLQHPN--IVQMLDSFETDKEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINT---LVLTSIKGTPLYMSPELVEEKPY-DHT-ADLWSMGCILYELFVG 196
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.1814 bits (191), Expect = 6.643e-16
Identity = 68/217 (31.34%), Postives = 105/217 (48.39%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFV----PEE------------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            +++  M+++IG GS+G+    K       +VIK   +    P+E            ++R  NI   + Y E F + RG +      C    LF+           R N    V L SE++I+    ++ + LK +H  KILH DIK +NI L K+G   L D+G ++V+ S T L        GT  Y++PE+   KP +   KSD+W+LG V+ EM
Sbjct:    1 MERYTMVSQIGEGSFGKAMLVKSKADGHLYVIKEINISRMSPKERDEARKEVCVLANMRHPNI---VSYKESFEE-RGNLYIVMDYCEGGDLFK-----------RINAQKGV-LFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVLNSTTEL---ARTCIGTPYYLSPEICENKPYNH--KSDMWALGCVLYEM 196
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004683.1 (pep scaffold:Pmarinus_7.0:GL488517:199:5283:1 gene:ENSPMAG00000004265.1 transcript:ENSPMAT00000004683.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.8626 bits (172), Expect = 1.969e-14
Identity = 51/154 (33.12%), Postives = 79/154 (51.30%), Query Frame = 1 
Query: 1672 LISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKL---SSDIKFSHKINLKA----LQFXXXXXXXXXXXXXNTNPDERLS 2112
            + +E ++     E+ + L  LH   I++ D+KPENILLD+SG   L D+G SK        +       GT+ Y+APE++N K  +    +D WS G+++ EM+ G L     D K +  + LKA     QF S + + +L+     NP  RL 
Sbjct:   29 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDESGHIGLTDFGLSKESIDH---EKKAYSFCGTVEYMAPEVVNRKGHTH--SADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSGEAQSLLRMLFKRNPGNRLG 177
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757])

HSP 1 Score: 90.1225 bits (222), Expect = 2.376e-19
Identity = 66/204 (32.35%), Postives = 104/204 (50.98%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFV----PE---ESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKL 1995
            +G G+ G V +CK  N    F +K        PE   +  RE+  N   +  E   +Y G+ + ++   ++  +  + M  +    I  N   R   ISE  + K+A  +L  L  LH+ K++H DIKP+NILL+++G+  LCD+G S    +  +     +   GT  Y+APE I G+P S    SD+WSLG+ I+E+  GK 
Sbjct:  227 LGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQS-EYIVRYYGMFTDDEN--SSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLA-----TTFTGTSFYMAPERIQGQPYS--VTSDVWSLGLTILEVANGKF 420
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061])

HSP 1 Score: 87.4261 bits (215), Expect = 2.035e-18
Identity = 63/204 (30.88%), Postives = 103/204 (50.49%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFV----PE---ESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKL 1995
            +G G+ G V +C+  N    F +K        PE   +  RE+  N+  K  +   +Y G+ + +++  + +   E      ++ T + N   R   ISE  I K+A  +L  L  LH+ K++H DIKP+NILL++ G   LCD+G S    +  ++        GT  Y+APE I G+P S     D+WSLG+ ++E+  G+ 
Sbjct:  220 LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKS-DYIVQYYGMFT-DEQSSSIYIAMEYMGGKSLEATYK-NLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFT-----GTSFYMAPERIQGQPYS--VTCDVWSLGLTLLEVAGGRF 413
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 81.6481 bits (200), Expect = 2.481e-17
Identity = 61/207 (29.47%), Postives = 105/207 (50.72%), Query Frame = 1 
Query: 1396 ITKIGNGSYGEVYQCKEANFDGQFVIKRF------FVPEESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIK-LAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINK-SDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            + K+GNG+Y  VY+           +K          P  ++REI++ +E+K+  +   Y  + + NK      +L  + MDN +K  + S      P   E  ++K   +++L  L   H+ KILH D+KP+N+L++K G+  L D+G ++       + +N  S    TL Y AP+++ G  ++  T  DIWS G ++ EM+ GK
Sbjct:   10 LEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENK-----LTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAF----GIPVNTFSSEVVTLWYRAPDVLMGS-RTYSTSIDIWSCGCILAEMITGK 206
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 82.8037 bits (203), Expect = 1.090e-16
Identity = 67/213 (31.46%), Postives = 104/213 (48.83%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPE------------ESVR-EININEEIKYLELFPKYRGLMSYNKKICAAFSLF-EKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGC---SKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            IG GS+G VY C          +K+  VP+            E++R E++  +++ +L +  +Y G  + N      +SLF E      +   IR    F  PLI       L  ++L  L  LH   ILH D+K +N+LLD+ G   + D+G    SK I S + + +      GT+ ++APE+++ K Q    K DIWSLG +++EM  GK
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIV-QYLGFENKNN----IYSLFLEYVAGGSVGSLIRMYGRFDEPLIKH-----LTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMR-----GTVFWMAPEMVDTK-QGYSAKVDIWSLGCIVLEMFAGK 1377
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 82.4185 bits (202), Expect = 1.254e-16
Identity = 68/200 (34.00%), Postives = 96/200 (48.00%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVREIN-INEEIKYLELFP-----KYRGLMSYNKKICAAFSLFEKSMDNKIKITI-RSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMM 1983
            IG GSYG VY+    + D    IK   V  E+  E+N I  EI  L+        KY G +   +K    + L E   +  ++  I RS+       +SENE      + L+ LK LH   ++H DIK  NILL       L D+G S ++ S          L GTL ++APE++  +  S  T SDIWSLG  ++EM+
Sbjct:   31 IGRGSYGVVYKAINKHTDQVVAIKE--VVYENDEELNDIMAEISLLKNLNHNNIVKYHGFI---RKSYELYILLEYCANGSLRRLISRSSTG-----LSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSA------LTLAGTLNWMAPEILGNRGAS--TLSDIWSLGATVVEML 212
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO35402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLJ0])

HSP 1 Score: 91.6633 bits (226), Expect = 4.868e-20
Identity = 57/212 (26.89%), Postives = 113/212 (53.30%), Query Frame = 1 
Query: 1378 LKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            ++K + +  +G GSYG V +C+  + +    IK+F   E+       ++RE+ +  ++++  L      L+   ++    F +FE  +D+ +   +   PN     + EN + K+ +++L  ++ +H+  I+H D+KPENIL+ +SG   LCD+G ++ + S        +D   T  Y APEL+ G  +  +   D+W++G ++ EM+ G+
Sbjct:    1 MEKYENLGLVGEGSYGMVMKCRHKDSNQIVAIKKFIESEDDKMVKKIAMREVRMLRQLRHENLV----NLIEVFRRKKRLFLVFE-FVDHTVLDDLERYPNG----LDENTVRKVMWQVLRAIEFIHRHNIIHRDVKPENILVSRSGIVKLCDFGFARTLASGQGEAY--TDYVATRWYRAPELLVGDTKYGRA-VDVWAVGCLLAEMLTGE 200
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO49690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG02])

HSP 1 Score: 85.5001 bits (210), Expect = 2.849e-18
Identity = 63/205 (30.73%), Postives = 98/205 (47.80%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVREININEE-------------IKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            IG GSYGEV+  K      Q+V+K+  + + SVRE    E              + Y E F    G +      C    L+ +    K            +PL  EN+I++   +I + L+ +H+  ILH D+K +NI L KS    + D G ++V+ S + +    + L GT  Y++PEL + KP +   KSD+W+LG  + EM
Sbjct:   12 IGKGSYGEVFLSKHKKDKKQYVLKKVDLQKASVRERKAAELEAKLLSQLRHPNIVSYRESFQDDTGFLYIAMNFCEGGDLYSRLKAQK-----------GIPL-DENQIVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKSKIIKVGDLGIARVLESSSDMA---TTLIGTPYYMSPELFSNKPYNH--KSDVWALGCCLYEM 199
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO37567 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFE6])

HSP 1 Score: 82.4185 bits (202), Expect = 4.331e-17
Identity = 63/211 (29.86%), Postives = 107/211 (50.71%), Query Frame = 1 
Query: 1384 KEQMITKIGNGSYGEVYQCKEANFDGQFV-IKRFFV-------PEESVREININEEIKYLELFPKYRGLMSYNKKICAA----FSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            K + + +IG G+YG VY+ K+   DG+FV +KR  +       P  ++REI + ++I         R L  ++  +  A     +L  + +D  +   +   P    P + E +I  L Y+IL  +  LH  +I+H DIKP+NIL+ K G+  + D+G ++V     +L    + +  TL Y APE++     S  T  DIWS+  ++ E+
Sbjct:    4 KYEEVAEIGTGAYGTVYKAKDLLNDGKFVALKRVRIQNSEEGMPLSTIREIALLKQIDNFAHPNVVRLLDIFHIPMLTARETHLNLVFEHVDQDLAAYLEYCPQ---PGLGEWKIKDLTYQILNGVDFLHTHRIVHRDIKPQNILVTKDGQVKIADFGLARVYKDAMAL----TSVVVTLWYRAPEVL--LQSSYATSVDIWSVACILAEL 205
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO46185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQY7])

HSP 1 Score: 85.1149 bits (209), Expect = 4.798e-17
Identity = 64/197 (32.49%), Postives = 109/197 (55.33%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPE--ESVREININEEIKYLELFPKYRGLMSYNKKIC--AAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRAT-LCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            +G G+YG VY C+    +   +IK+  V E  +  R+  +NE +K L +F     +  Y+  +   A   + E +    I   ++        L+ E+EI++L  +IL+ L+ +HK +ILH D+K +NILL+K  +   + D+G SK++ S++      + + G+  YI+PEL  GKP +   KSD+WSLG V+ E+
Sbjct:   10 VGRGAYGTVYLCRRLVDNFLVIIKQIPVEEMTKEERQSALNE-VKVLSMFQHPNIIRYYDSFVQEKALMIVMEYAQGGTIYDYLQQRGG---KLMDEDEILRLFVQILLALRHVHKGQILHRDLKTQNILLNKKRKVVKIGDFGISKILSSKS----KANTVIGSPCYISPELCEGKPYNQ--KSDVWSLGCVLYEL 196
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO38062 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDX6])

HSP 1 Score: 82.4185 bits (202), Expect = 5.931e-17
Identity = 61/213 (28.64%), Postives = 101/213 (47.42%), Query Frame = 1 
Query: 1390 QMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVRE------ININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHK-WKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSD----KTKSDIWSLGIVIIEMMEGKL 1995
            Q I ++G+G+YG VY+           +K+      S  +      ++I+  +        + G +     +     L + S+ +  K  + S P+ R+P   E  + K+A  ++  L+ LH   K++H D+KP NIL+D+ G   LCD+G S  +    +  ++     G   Y+APE IN  P  D      +SDIWSLGI +IE+  GK 
Sbjct:   59 QEIRELGHGAYGYVYEMLHVPTSTVMAVKKIRANVNSTEQKRLLMDLDISMRVSDYPYTVHFYGALFREGDVWICMELMKTSLYDLYK-QVFSKPDRRIP---EEVLGKIAVSVVSALEYLHSNLKVIHRDVKPSNILVDERGNFKLCDFGISGQLVDSLAKTVDA----GCKPYMAPERIN--PDRDMKGYDIRSDIWSLGITMIELATGKF 261
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: ENSORLT00000001547.2 (cyclin-dependent kinase-like 1 [Source:NCBI gene;Acc:101157382])

HSP 1 Score: 97.0561 bits (240), Expect = 2.675e-21
Identity = 62/214 (28.97%), Postives = 111/214 (51.87%), Query Frame = 1 
Query: 1369 MKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            M  ++K + + KIG GSYG V++C+  +      IK+F   EE       ++REI + +++K++ L      +    +++   F   E+++ N++    R  P        E ++  + ++ L  +   HK   +H D+KPENILL K+G   LCD+G ++++   T  + + +D   T  Y APEL+ G  Q      D+W+LG V  E+++G
Sbjct:    1 MDMMEKYEKLAKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEEDPVIKKIALREIRMLKQLKHVNLV-NLLEVFRRKRRLHLVFEFCEQTVLNELDRHPRGVP--------EAQLKSIVWQTLQAVNFCHKHNCIHRDVKPENILLTKTGVIKLCDFGFARIL---TGPEDDYTDYVATRWYRAPELLVGDTQYG-PPVDVWALGCVFAELLDG 201
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: cdkl1 (cyclin dependent kinase like 1 [Source:NCBI gene;Acc:101159782])

HSP 1 Score: 87.8113 bits (216), Expect = 5.321e-18
Identity = 65/238 (27.31%), Postives = 113/238 (47.48%), Query Frame = 1 
Query: 1297 VNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            VN     +   +RIT  +     E K+++K + I KIG GSYG V++C+         IK+F   +E       ++REI + +++K+  L      +    +K+   F   + ++ N++    R  P        E+ +  + ++ L  +   HK   +H D+KPENIL+ K     LCD+G ++++   T      +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:   36 VNRKSAKIKYRVRITADLL----EQKKMEKYEKIAKIGEGSYGVVFKCRSRETGQIVAIKKFVESDEDPIIRKIALREIRMLKQLKHANLV-NLMEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVP--------EHLVKSITWQTLQAVNFCHKQNCIHRDVKPENILITKQQVIKLCDFGFARIL---TGPGDYYTDYVATRWYRAPELLVGDTQYG-PPVDVWAIGCVFAELLSG 256
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: cdkl1 (cyclin dependent kinase like 1 [Source:NCBI gene;Acc:101159782])

HSP 1 Score: 87.8113 bits (216), Expect = 5.666e-18
Identity = 65/238 (27.31%), Postives = 113/238 (47.48%), Query Frame = 1 
Query: 1297 VNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEE-------SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEG 1989
            VN     +   +RIT  +     E K+++K + I KIG GSYG V++C+         IK+F   +E       ++REI + +++K+  L      +    +K+   F   + ++ N++    R  P        E+ +  + ++ L  +   HK   +H D+KPENIL+ K     LCD+G ++++   T      +D   T  Y APEL+ G  Q      D+W++G V  E++ G
Sbjct:   36 VNRKSAKIKYRVRITADLL----EQKKMEKYEKIAKIGEGSYGVVFKCRSRETGQIVAIKKFVESDEDPIIRKIALREIRMLKQLKHANLV-NLMEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVP--------EHLVKSITWQTLQAVNFCHKQNCIHRDVKPENILITKQQVIKLCDFGFARIL---TGPGDYYTDYVATRWYRAPELLVGDTQYG-PPVDVWAIGCVFAELLSG 256
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: cdk6 (cyclin dependent kinase 6 [Source:NCBI gene;Acc:101168879])

HSP 1 Score: 82.0333 bits (201), Expect = 2.001e-16
Identity = 60/212 (28.30%), Postives = 108/212 (50.94%), Query Frame = 1 
Query: 1396 ITKIGNGSYGEVYQCKEANFDGQFV-IKRFFV-------PEESVREININEEIKYLELFPKYRGLMSYNKKICAA--------FSLFEKSMDNKIKITIRSNPNFRVPLISENEIIK-LAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEM 1980
            + +IG G+YG+VY+ ++   +G+FV +KR  V       P  ++RE+ +   ++ LE F     +  ++  +C           +L  + +D  +   +   P+  VP     E IK + Y++L  L  LH  +++H D+KP+NIL+   G+  L D+G +++     S Q+  + +  TL Y APE++     S  T  D+WS+G +  EM
Sbjct:   13 VAEIGEGAYGKVYKARDLKNEGRFVALKRVRVQTEEEGMPLSTIREVAV---LRQLEAFEHPNVVRLFD--VCTVSRTDRETKLTLVFEHVDQDLTTYLEKVPDPGVP----PETIKDMMYQLLQGLDFLHSHRVVHRDLKPQNILVTSGGQIKLADFGLARIY----SFQMALTSVVVTLWYRAPEVLLQS--SYATPVDLWSVGCIFAEM 209
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985])

HSP 1 Score: 84.7297 bits (208), Expect = 2.326e-16
Identity = 85/273 (31.14%), Postives = 128/273 (46.89%), Query Frame = 1 
Query: 1405 IGNGSYGEVYQCKEANFDGQFVIKRFFVPE-ESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLI----------SENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDK-SGRATLCDYGCSKVI-----CSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK-----LSSDIKFSHKINL-----KALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAF 2142
            +G G+YG VY  ++ +   +  IK   +PE +S     ++EEI   +   K+R ++ Y         L   S D  IKI +   P   +  +          +E  II    ++L  LK LH  +I+H DIK +N+L++  SG   + D+G SK +     C++T          GTL Y+APE+I+  P+     +DIWSLG  IIEM  GK     L S      K+ +     K  +  S + K  +  C   NPD R +A ELL +D F
Sbjct:  639 LGKGTYGVVYAGRDLSNQVRIAIKE--IPEKDSTYSQPLHEEIALHKRL-KHRNIVQY---------LGSVSQDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEPTIIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTET--------FAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPKVPECMSDEAKGFIMSCFEPNPDNRATAAELL-MDTF 890
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000078505.1 (SMESG000078505.1)

HSP 1 Score: 1194.1 bits (3088), Expect = 0.000e+0
Identity = 619/670 (92.39%), Postives = 638/670 (95.22%), Query Frame = 1 
Query:  160 MYSVRTENNILKELKIESFYYVNDIVKYFSDKYSNSNRRLPHFELIYENMILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDXXXXXXXXDLQAFKKHLESHPKDSFIPNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIYYYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQAXXXXXXXNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEIRFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINLKALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAFKDIQSATTQ 2169
            MYSVRTENNILKELKIESFYYVNDIVKYFSDKYSNSNRRLPHFELIYENMILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDKIIKIIKKDLQAFKKHLESHPKDS I NTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIY YIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQALKLLLKKNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEI FFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMI KIGNGSYGEVYQCKEANFDGQFVIKRF VPEESVREININEEIKY +L   YRGLM Y+++IC AFSLFE+S+D KIK   + +        +E +I+++AYEIL ELK LHKW+I+H DIKPENILLDK+GRATLCDYGCSKVICSQTSLQINKSDL GTLGYIAPELI GKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINL+ALQFKSVKLKKILKKCL T+PD+RLSAKELLQLDAFKDIQSATTQ
Sbjct:    1 MYSVRTENNILKELKIESFYYVNDIVKYFSDKYSNSNRRLPHFELIYENMILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDKIIKIIKKDLQAFKKHLESHPKDSLIHNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIYSYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQALKLLLKKNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEISFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMIRKIGNGSYGEVYQCKEANFDGQFVIKRFIVPEESVREININEEIKYFKLLSNYRGLMRYDREICVAFSLFEESLDKKIKSYCQKSEE------NEKKILRVAYEILKELKELHKWEIIHRDIKPENILLDKNGRATLCDYGCSKVICSQTSLQINKSDLAGTLGYIAPELIKGKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINLEALQFKSVKLKKILKKCLKTDPDKRLSAKELLQLDAFKDIQSATTQ 664
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000078505.1 (SMESG000078505.1)

HSP 1 Score: 1095.88 bits (2833), Expect = 0.000e+0
Identity = 570/621 (91.79%), Postives = 589/621 (94.85%), Query Frame = 1 
Query:  307 MILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDXXXXXXXXDLQAFKKHLESHPKDSFIPNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIYYYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQAXXXXXXXNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEIRFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINLKALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAFKDIQSATTQ 2169
            MILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDKIIKIIKKDLQAFKKHLESHPKDS I NTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIY YIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQALKLLLKKNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEI FFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMI KIGNGSYGEVYQCKEANFDGQFVIKRF VPEESVREININEEIKY +L   YRGLM Y+++IC AFSLFE+S+D KIK   + +        +E +I+++AYEIL ELK LHKW+I+H DIKPENILLDK+GRATLCDYGCSKVICSQTSLQINKSDL GTLGYIAPELI GKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINL+ALQFKSVKLKKILKKCL T+PD+RLSAKELLQLDAFKDIQSATTQ
Sbjct:    1 MILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDKIIKIIKKDLQAFKKHLESHPKDSLIHNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIYSYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQALKLLLKKNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEISFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMIRKIGNGSYGEVYQCKEANFDGQFVIKRFIVPEESVREININEEIKYFKLLSNYRGLMRYDREICVAFSLFEESLDKKIKSYCQKSEE------NEKKILRVAYEILKELKELHKWEIIHRDIKPENILLDKNGRATLCDYGCSKVICSQTSLQINKSDLAGTLGYIAPELIKGKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINLEALQFKSVKLKKILKKCLKTDPDKRLSAKELLQLDAFKDIQSATTQ 615
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000078507.1 (SMESG000078507.1)

HSP 1 Score: 665.226 bits (1715), Expect = 0.000e+0
Identity = 391/684 (57.16%), Postives = 488/684 (71.35%), Query Frame = 1 
Query:  160 MYSVRTENNILKELKIESFYYVNDIVKYFSDKYSNSNRRLPHFELIYENMILNREKHLQFYKICQFKEIYMGSVEGYM--SRFGDKDQDVIVEVVVQCFLSESIFLIMKQNYEISEVTEILARLTQISGL--------LEKDDINRIPEV-KRDSGKIFISWTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDXXXXXXXXD--LQAFKKHLESHPK-DSFIPNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDSDFTVIYYYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQAXXXXXXXNSGKSI-MKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENLRIPLEEIRFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKS-DLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKLSSDIKFSHKINLK-ALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAFKDIQSA 2160
            MY V+ ENN    +K +   YV DI+KY  ++    N+  P  ELIY+ +ILN EK LQFYKI   K IYMG +E Y+  S  GDKD DV VEVVVQC  SESIFLIMKQN  I +V EI+ARL +IS L         + +D   + ++ K+DS +IFISWTP+YLH  YNR LIEKYFW G DS +GWIK+ ++ +   +    L+ FK +LE +   +S +    L+ +   S+ YFCK+YSE F KE E++WK  IK+ +DF VIYY+IR+ IFI L +  N      + W    S + I+I+ L+LLL+ + G    ++KF+KHV +GE++ E +E++I+ YF  YG LK+KM KSTE +++PL E+  F++ KIAQI CGI++DL+YFVNYDE+DL  PI+I+ +MTIH EEM RLKKEQ   KIG GSYG+VY  KEAN D +F IK F    +SVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKS+DNKIKITIRSNPNFRVPLISENEIIKLAYEIL ELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSK+IC+QT++ ++K  +  GT  Y APE+      SD  K+DIWSLGIVIIEM+EGKL+   K    IN K  L+F S  L+ IL KCL  +   R SA+ELL+L+ FKDIQ+ 
Sbjct:    1 MYWVKRENNDPIPVKRKKCLYVKDIIKYCLNEDYTPNQSFPPCELIYDRIILNHEKPLQFYKISSDKVIYMGPLEEYILKSGIGDKDPDVFVEVVVQCHYSESIFLIMKQNDNILKVKEIVARLIRISSLPGIYNINGFQLEDFIALSQILKKDSQRIFISWTPDYLHRDYNRYLIEKYFWYGNDSEEGWIKSFNRFLNNNENRFYLRDFKTYLERNRNCNSSLNRKSLNALFETSEFYFCKYYSEFFYKEIEQKWKCHIKNVADFPVIYYFIRLGIFIALQEYYN-----RRSWWDVSSMNDIIIKGLELLLQNDQGGEFFIQKFIKHVCVGEISGEYLENEIENYFHYYGNLKIKMTKSTEFIKVPLGEMSLFEINKIAQIFCGIDEDLIYFVNYDEQDLKDPIKISANMTIHLEEMTRLKKEQKRDKIGEGSYGKVYLFKEANSDDKFAIKIFNDSAKSVREININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSLDNKIKITIRSNPNFRVPLISENEIIKLAYEILKELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKLICNQTNIIVHKKPNSFGTQDYEAPEISKNNSYSD--KADIWSLGIVIIEMIEGKLNQYAK-DKNINFKFRLRFISENLRNILMKCLTNDMAARSSAEELLELEVFKDIQNT 676
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000078509.1 (SMESG000078509.1)

HSP 1 Score: 242.276 bits (617), Expect = 4.531e-75
Identity = 140/204 (68.63%), Postives = 162/204 (79.41%), Query Frame = 1 
Query: 1567 MSYNKKICAAFSLFEKSMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVICSQTSLQINKS-DLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGKLSS-----DIKFSHKINLKALQFXXXXXXXXXXXXXNTNPDERLSAKELLQLDAFKDIQSA 2160
            MSYNKKICAAF LFEKS+DNKIKITIRSNPNFRVPLISENEIIKLAYEIL ELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSK+IC+QT++ ++K  +  GT  Y APE+      SD  K+DIWSLGIVIIEM+EGKL+      +I F+ +     L+F S  L+ IL KCL T+P  R SA+ELL+L+ FKDIQ+ 
Sbjct:    1 MSYNKKICAAFLLFEKSLDNKIKITIRSNPNFRVPLISENEIIKLAYEILKELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKLICNQTNIIVHKKPNSFGTQDYEAPEISENNSYSD--KADIWSLGIVIIEMIEGKLNQYAKDKNINFAFR-----LRFISENLRNILMKCLITDPAARSSAEELLELEVFKDIQNT 197
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000073002.1 (SMESG000073002.1)

HSP 1 Score: 119.398 bits (298), Expect = 4.772e-29
Identity = 82/267 (30.71%), Postives = 138/267 (51.69%), Query Frame = 1 
Query: 1207 LRIPLEEIRFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIHFEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESV-REININEEIKYLELFPKYRGLMSYNKKICAAFSLFEK-SMDNKIKITIRSNPNFRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATLCDYGCSKVI---CSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSLGIVIIEMMEGK 1992
            L IP       + K++    CG+  D  Y ++    D        E+  + FE M+ ++   +  ++ +G +G ++ C+       F+IK+     E++ REI IN +  Y +   K  GL+      C A   F   S+ + I+         ++  + E EI  + Y+IL+++  LH+  I+H DIKP+NI+ D+   A L D+G +K +    ++  L+  KS +PGT+ Y+APEL+ G P S+K   DIWS G+VI+EM+ GK
Sbjct:   11 LAIPSTPQTVIEAKRVIACKCGVSIDDFYCIDLYNSDKPNDWDTYEY-ELMFERMRNIENINITRELASGGFGRIFICQNKFSTNNFLIKKSINETENLHREIFINLQFFYSDKLFKISGLIRNENHPCLAMPYFPGGSLASYIE---------QIRCLDEKEIGNILYQILMQINELHRLGIIHRDIKPDNIVFDEKKNAKLIDFGLAKCMDEWKNKDQLENLKSYVPGTVKYMAPELVKGSPYSNKI--DIWSFGMVIVEMVTGK 265
The following BLAST results are available for this feature:
BLAST of Kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDKL33.439e-2133.92cyclin dependent kinase like 3 [Source:HGNC Symbol... [more]
CDKL36.297e-2133.62cyclin dependent kinase like 3 [Source:HGNC Symbol... [more]
CDKL37.302e-2133.62cyclin dependent kinase like 3 [Source:HGNC Symbol... [more]
STK368.821e-1729.38serine/threonine kinase 36 [Source:HGNC Symbol;Acc... [more]
CDKL41.023e-1628.64cyclin dependent kinase like 4 [Source:HGNC Symbol... [more]
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BLAST of Kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdkl-13.319e-1829.30Cyclin-dependent kinase-like 1 [Source:UniProtKB/... [more]
cdkl-14.473e-1829.30Cyclin-dependent kinase-like 1 [Source:UniProtKB/... [more]
cdkl-11.092e-1729.30Cyclin-dependent kinase-like 1 [Source:UniProtKB/... [more]
cst-21.271e-1533.02Caenorhabditis STE20-like kinase [Source:UniProtK... [more]
cst-11.294e-1533.02Serine/threonine-protein kinase cst-1 Serine/threo... [more]
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BLAST of Kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG72361.762e-1926.92gene:FBgn0031730 transcript:FBtr0302950[more]
CG72362.244e-1927.85gene:FBgn0031730 transcript:FBtr0343388[more]
CG72362.497e-1927.85gene:FBgn0031730 transcript:FBtr0343387[more]
CG72363.109e-1927.85gene:FBgn0031730 transcript:FBtr0343389[more]
png8.329e-1626.19gene:FBgn0000826 transcript:FBtr0070234[more]
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BLAST of Kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nek16.171e-1731.31NIMA-related kinase 1 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
cdkl11.148e-1627.57cyclin-dependent kinase-like 1 (CDC2-related kinas... [more]
map3k152.461e-1632.23mitogen-activated protein kinase kinase kinase 15 ... [more]
map3k152.461e-1632.23mitogen-activated protein kinase kinase kinase 15 ... [more]
map3k152.529e-1632.23mitogen-activated protein kinase kinase kinase 15 ... [more]
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BLAST of Kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDKL16.001e-1626.73cyclin dependent kinase like 1 [Source:NCBI gene;A... [more]
ephb16.267e-1633.33EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626... [more]
CDKL16.514e-1626.73cyclin dependent kinase like 1 [Source:NCBI gene;A... [more]
ephb17.061e-1633.33EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626... [more]
ephb17.084e-1633.33EPH receptor B1 [Source:Xenbase;Acc:XB-GENE-488626... [more]
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BLAST of Kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdkl31.032e-2132.90cyclin-dependent kinase-like 3 [Source:MGI Symbol;... [more]
Cdkl31.032e-2132.90cyclin-dependent kinase-like 3 [Source:MGI Symbol;... [more]
Cdkl36.027e-2132.90cyclin-dependent kinase-like 3 [Source:MGI Symbol;... [more]
Cdkl31.169e-2032.90cyclin-dependent kinase-like 3 [Source:MGI Symbol;... [more]
Cdkl31.169e-2032.90cyclin-dependent kinase-like 3 [Source:MGI Symbol;... [more]
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BLAST of Kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q4R8T9|CDKL3_MACFA3.390e-2033.62Cyclin-dependent kinase-like 3 OS=Macaca fascicula... [more]
sp|Q8IVW4|CDKL3_HUMAN3.507e-2033.62Cyclin-dependent kinase-like 3 OS=Homo sapiens OX=... [more]
sp|Q9JM01|CDKL3_RAT8.107e-2032.90Cyclin-dependent kinase-like 3 OS=Rattus norvegicu... [more]
sp|Q8BLF2|CDKL3_MOUSE1.160e-1932.90Cyclin-dependent kinase-like 3 OS=Mus musculus OX=... [more]
sp|P32490|MKK1_YEAST1.650e-1732.35MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cere... [more]
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BLAST of Kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q0CGF31.131e-1932.46cyclin-dependent kinase-like 3 isoform X3 OS=Mesoc... [more]
A0A4P9YQ681.487e-1934.85Kinase-like protein OS=Rozella allomycis (strain C... [more]
A0A182M7R02.803e-1930.28Protein kinase domain-containing protein OS=Anophe... [more]
A0A1W0WA828.914e-1928.62Cyclin-dependent kinase-like 1 OS=Hypsibius dujard... [more]
A0A0L8H3E81.083e-1829.25Protein kinase domain-containing protein OS=Octopu... [more]
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BLAST of Kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000033332.19.018e-1927.96cyclin-dependent kinase-like 1 [Source:NCBI gene;A... [more]
ENSAMXT00000057054.11.280e-1827.96cyclin-dependent kinase-like 1 [Source:NCBI gene;A... [more]
ENSAMXT00000052448.11.280e-1827.96cyclin-dependent kinase-like 1 [Source:NCBI gene;A... [more]
ENSAMXT00000004552.27.534e-1729.21cyclin dependent kinase like 2 [Source:NCBI gene;A... [more]
cdkl19.733e-1727.49cyclin dependent kinase like 1 [Source:NCBI gene;A... [more]
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BLAST of Kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k21.258e-1632.54mitogen-activated protein kinase kinase kinase 2 [... [more]
cdk41.524e-1627.52cyclin-dependent kinase 4 [Source:ZFIN;Acc:ZDB-GEN... [more]
STK361.590e-1630.33serine/threonine kinase 36 [Source:HGNC Symbol;Acc... [more]
ENSPMAT00000007414.16.643e-1631.34pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1... [more]
ENSPMAT00000004683.11.969e-1433.12pep scaffold:Pmarinus_7.0:GL488517:199:5283:1 gene... [more]
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BLAST of Kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
MKK12.376e-1932.35MAPKK involved in the protein kinase C signaling p... [more]
MKK22.035e-1830.88MAPKK involved in the protein kinase C signaling p... [more]
PHO852.481e-1729.47Cyclin-dependent kinase; has ten cyclin partners; ... [more]
BCK11.090e-1631.46MAPKKK acting in the protein kinase C signaling pa... [more]
CDC151.254e-1634.00Protein kinase of the Mitotic Exit Network; locali... [more]
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BLAST of Kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO354024.868e-2026.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496902.849e-1830.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375674.331e-1729.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461854.798e-1732.49Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380625.931e-1728.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000001547.22.675e-2128.97cyclin-dependent kinase-like 1 [Source:NCBI gene;A... [more]
cdkl15.321e-1827.31cyclin dependent kinase like 1 [Source:NCBI gene;A... [more]
cdkl15.666e-1827.31cyclin dependent kinase like 1 [Source:NCBI gene;A... [more]
cdk62.001e-1628.30cyclin dependent kinase 6 [Source:NCBI gene;Acc:10... [more]
si:ch211-1i11.32.326e-1631.14mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000078505.10.000e+092.39SMESG000078505.1[more]
SMESG000078505.10.000e+091.79SMESG000078505.1[more]
SMESG000078507.10.000e+057.16SMESG000078507.1[more]
SMESG000078509.14.531e-7568.63SMESG000078509.1[more]
SMESG000073002.14.772e-2930.71SMESG000073002.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032881 ID=SMED30032881|Name=Kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2325bp
TAGAACCTGATTCAGCACTCAAATACTTTTCAGAAAATCAATACCAAAAT
TGCATGTTCACCATTTTGGACTTTAGAATATTGATAAACCATTTCAGCCA
TGCATTTATAGTCATTGAGTTGAGCAATCACAATACAATATTTGATCTCA
ACATACATTATGTACTCGGTGAGGACTGAGAACAATATCTTAAAGGAGTT
AAAAATTGAGAGCTTTTATTATGTGAACGATATAGTAAAGTATTTCTCTG
ACAAATATTCCAATTCCAATCGGAGGCTTCCCCATTTCGAATTAATATAT
GAAAATATGATTTTGAATCGTGAGAAACATCTGCAATTTTATAAAATATG
TCAGTTTAAAGAGATTTATATGGGTTCGGTGGAAGGATACATGTCACGCT
TTGGAGATAAAGATCAAGACGTCATTGTGGAGGTTGTGGTACAATGCTTC
TTATCAGAATCTATATTTTTAATAATGAAACAAAATTATGAAATATCAGA
GGTAACAGAAATTCTAGCTAGGTTAACTCAGATTTCTGGCTTACTTGAAA
AAGATGACATCAATCGAATCCCAGAGGTAAAAAGAGATTCGGGAAAAATA
TTCATAAGCTGGACTCCCGAATATCTTCATGAAGGTTATAATCGGAATTT
AATAGAAAAATATTTTTGGAACGGGGGAGACTCAGTTGACGGATGGATAA
AAACTTCAGATAAAATCATAAAAATTATCAAAAAAGATCTTCAAGCTTTC
AAAAAGCACCTGGAAAGCCATCCCAAGGACAGTTTTATTCCCAATACTCC
CTTATCGAAAGTGGTTAGAAGATCAAAATCCTACTTTTGTAAGTGGTATT
CTGAAAGTTTTGATAAAGAATGTGAAGAAGAATGGAAATCCAAAATAAAA
GATGATTCTGATTTCACTGTCATCTATTACTACATTCGGATTGCAATATT
CATTGTGCTACACAAGGAATGCAATTTGAATCCTCCCTTTCACAAATGTT
GGCCTAAAACTGATTCGTTTGATGCCATTTTAATTCAAGCTCTCAAACTT
TTGCTTAAAAAGAACAGTGGAAAATCAATCATGAAAAAATTTGTAAAACA
TGTTAGCATGGGAGAAATGACAAGAGAAATCATGGAAGACAAAATTGACA
AATATTTTTTACAATACGGAGTACTCAAAGTAAAAATGATAAAGTCAACG
GAGAATCTACGAATCCCACTCGAAGAAATAAGATTTTTTCAACTGAAGAA
AATTGCACAAATTACTTGTGGGATTGAGAAAGATTTGCTATATTTTGTTA
ATTATGACGAGCGAGATTTGAATATTCCAATCAGAATAACAGAACACATG
ACAATCCATTTTGAAGAAATGAAAAGATTAAAAAAAGAACAAATGATTAC
AAAAATTGGAAATGGGTCTTATGGGGAAGTTTATCAATGCAAAGAAGCTA
ATTTTGATGGTCAATTCGTAATCAAAAGATTTTTCGTTCCTGAAGAAAGC
GTTCGAGAAATTAATATAAATGAAGAAATAAAATATTTGGAATTGTTTCC
AAAGTATCGCGGGTTGATGAGCTATAACAAAAAGATCTGTGCCGCATTCT
CCTTATTTGAAAAATCGATGGACAACAAAATAAAAATAACTATTAGAAGT
AATCCTAATTTTCGAGTTCCTCTAATTAGCGAAAATGAGATTATTAAGTT
GGCATACGAAATCCTCATAGAATTGAAAGTGCTCCACAAATGGAAAATTC
TTCATCTCGATATAAAACCCGAAAATATTCTGTTGGATAAAAGTGGAAGG
GCTACCCTATGTGATTATGGTTGCTCAAAAGTGATTTGTAGTCAAACAAG
TTTACAAATAAATAAATCAGATTTACCTGGTACTCTGGGCTATATAGCTC
CGGAATTAATAAATGGCAAGCCACAATCAGACAAAACCAAAAGCGACATT
TGGTCGCTTGGCATTGTAATAATCGAAATGATGGAAGGAAAATTATCGAG
TGATATAAAATTCTCCCATAAAATCAACCTAAAAGCTTTGCAGTTTAAAT
CCGTAAAACTAAAAAAGATTTTAAAGAAATGTCTAAATACTAATCCGGAT
GAAAGATTATCTGCCAAAGAACTTCTACAACTGGACGCTTTCAAGGATAT
TCAAAGCGCTACAACACAATAAAACCAAATTGTTTTGATTTTAGAGCCTC
AAATTGTTTTTCTTCCATACAACAAGAAATGCAGTCTCTCTGTGTTCTAA
AATTGAAAAGTTGATTATCTTAGTGATGCACAGATGAGCCTTGTGCACGC
GAAACGAATAAACAGCGCATTTTTT
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protein sequence of SMED30032881-orf-1

>SMED30032881-orf-1 ID=SMED30032881-orf-1|Name=SMED30032881-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=671bp
MYSVRTENNILKELKIESFYYVNDIVKYFSDKYSNSNRRLPHFELIYENM
ILNREKHLQFYKICQFKEIYMGSVEGYMSRFGDKDQDVIVEVVVQCFLSE
SIFLIMKQNYEISEVTEILARLTQISGLLEKDDINRIPEVKRDSGKIFIS
WTPEYLHEGYNRNLIEKYFWNGGDSVDGWIKTSDKIIKIIKKDLQAFKKH
LESHPKDSFIPNTPLSKVVRRSKSYFCKWYSESFDKECEEEWKSKIKDDS
DFTVIYYYIRIAIFIVLHKECNLNPPFHKCWPKTDSFDAILIQALKLLLK
KNSGKSIMKKFVKHVSMGEMTREIMEDKIDKYFLQYGVLKVKMIKSTENL
RIPLEEIRFFQLKKIAQITCGIEKDLLYFVNYDERDLNIPIRITEHMTIH
FEEMKRLKKEQMITKIGNGSYGEVYQCKEANFDGQFVIKRFFVPEESVRE
ININEEIKYLELFPKYRGLMSYNKKICAAFSLFEKSMDNKIKITIRSNPN
FRVPLISENEIIKLAYEILIELKVLHKWKILHLDIKPENILLDKSGRATL
CDYGCSKVICSQTSLQINKSDLPGTLGYIAPELINGKPQSDKTKSDIWSL
GIVIIEMMEGKLSSDIKFSHKINLKALQFKSVKLKKILKKCLNTNPDERL
SAKELLQLDAFKDIQSATTQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0051726regulation of cell cycle
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0004693cyclin-dependent protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 411..482
e-value: 1.1E-12
score: 49.9
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 483..536
e-value: 1.1E-12
score: 49.9
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 413..536
e-value: 6.0E-12
score: 45.5
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 410..536
score: 13.319
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 416..439
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 411..536