WD repeat-containing protein 75

Overview
NameWD repeat-containing protein 75
Smed IDSMED30032876
Length (bp)2453
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of WD repeat-containing protein 75 (SMED30032876) t-SNE clustered cells

Violin plots show distribution of expression levels for WD repeat-containing protein 75 (SMED30032876) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of WD repeat-containing protein 75 (SMED30032876) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for WD repeat-containing protein 75 (SMED30032876) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032876

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30032876h1SMcG0014252 SmedASXL_015602SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30032876h1SMcG0014252 SmedASXL_015602SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of WD repeat-containing protein 75 vs. Ensembl Human
Match: WDR75 (WD repeat domain 75 [Source:HGNC Symbol;Acc:HGNC:25725])

HSP 1 Score: 102.834 bits (255), Expect = 8.521e-22
Identity = 88/292 (30.14%), Postives = 130/292 (44.52%), Query Frame = 2
Query:  500 RSKVHY---LTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDH-------QGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDM---DCIHRL 1327
            R+K H     T VACHP+E  IA+G   GKI +W +     K  +T  HWH   +  L FS  G  L SGG E VLV W  +    +K +   PRL + IE I   V    + F  + SDN I I+  +       QG   +   ++GL+  P T                             ++LNG  G LQFY L      Y LD+  Q +  +       G IQ++L   +  C G ++AT E     +T++  Q  +++++++   Q + + TKI+M   DCI  L
Sbjct:  197 RNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDAT---EKNKEFLPRLGATIEHIS--VSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRT---------------------------KALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDY------GLIQIELTKAAFGCFGNWLATVEQRQEKETELELQ--MKLWMYNKKTQGFILNTKINMPHEDCITAL 448          
BLAST of WD repeat-containing protein 75 vs. Ensembl Fly
Match: l(2)05287 (gene:FBgn0284251 transcript:FBtr0114615)

HSP 1 Score: 94.3597 bits (233), Expect = 2.440e-19
Identity = 87/300 (29.00%), Postives = 139/300 (46.33%), Query Frame = 2
Query:  497 KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRF-TVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIW--SDDNQSYAMETKIDMDCIHRLSDMVFH---PVDNRYLACTT 1378
            K +K H +T V   P E + AT ++ G+I++W D         T++HWH   + +L FS +G  ++SGGHE VLV+W  +   ++K     PR+ S I  I   V  ++E  L+   DN+I+++       G  +     +Q   T   K        P+GLR    L P+ ++ V LNG  G LQFY    +S  Y L V   N   E  N+ I      ++   +    ++AT    G    D+     +R+  W  ++  QSY + T+I++   +    ++F     VDN  L C T
Sbjct:  197 KSAKQHTITCVKMSPCEMVAATADSEGQIFVWRDFEKKDSMTNTLFHWHHTEVTSLAFSPSGVSIYSGGHECVLVKWTVASPGYRK---YLPRMSSVIRHI--VVSDDNENVLVCTEDNAIQLIS------GSDNIIKSTVQH-FTYETKDKTGQSKFPLGLR----LNPRTNTLV-LNGRSGHLQFYSAYTKSLLYNLRVVDTNVHNEEANHII---YNTRITRAAFNINWMAT----GEVYNDLVNFAEVRLKFWHYNERLQSYILNTEIELPHENGFKAIIFSNQFQVDN--LRCAT 470          
BLAST of WD repeat-containing protein 75 vs. Ensembl Zebrafish
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478])

HSP 1 Score: 102.834 bits (255), Expect = 5.250e-22
Identity = 90/333 (27.03%), Postives = 150/333 (45.05%), Query Frame = 2
Query:  398 AFCAKLGIMGIVENLTVSVICINDNKSFNYKVI---KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTT 1378
            AF      +    +L ++V      K++++ +    K++  +  T VACHP++  IA+G   GKI +W + N   +  ++  HWH  ++  L F+  G  L SGG E VLV+W++       K+   PRL   I  + +    + + F    SDN I I+   +  F      SGLIQ  L   + VS    ++P             S  ++LNG  G LQFY L R    Y LD+  Q +  E+      G  Q ++V       G ++AT E  G   +D+  +  L+++ + +  QS+ + T +      R++ M F   +   +  TT
Sbjct:  165 AFGRGGEFIAFSRHLQLNVYFFRKQKTYSFSLKATDKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWRNFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYG---DMSKKEFLPRLGGSISHVSA--SADGQLFCTAHSDNKISII---ESSF----KVSGLIQG-LVRGDAVSTDLMIDPR------------SKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEA------GLDQFEVVKAVFDVKGSWLATVEERGHKTSDL--EFFLKLWAFDETTQSFVLNTTVTEAHSERITSMCFSSSEETTMLVTT 464          
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750])

HSP 1 Score: 100.908 bits (250), Expect = 3.293e-21
Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342
            H+  C  +G     +  V+ L +S+      K F   +   SK    +  T VACHP E  IATG   G+I +W + N   K+  VY   HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I +        T+ E   I++ D S+++ G  QG        +GL+  P                            S+ ++LNG  G LQFY L+     Y LD+  Q +  ++      G   + LV    ++ G+++AT E L   +     +  ++ + + D +QS+ + T I       ++ + F
Sbjct:  138 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 433          
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750])

HSP 1 Score: 100.523 bits (249), Expect = 3.869e-21
Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342
            H+  C  +G     +  V+ L +S+      K F   +   SK    +  T VACHP E  IATG   G+I +W + N   K+  VY   HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I +        T+ E   I++ D S+++ G  QG        +GL+  P                            S+ ++LNG  G LQFY L+     Y LD+  Q +  ++      G   + LV    ++ G+++AT E L   +     +  ++ + + D +QS+ + T I       ++ + F
Sbjct:  155 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 450          
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750])

HSP 1 Score: 100.523 bits (249), Expect = 4.032e-21
Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342
            H+  C  +G     +  V+ L +S+      K F   +   SK    +  T VACHP E  IATG   G+I +W + N   K+  VY   HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I +        T+ E   I++ D S+++ G  QG        +GL+  P                            S+ ++LNG  G LQFY L+     Y LD+  Q +  ++      G   + LV    ++ G+++AT E L   +     +  ++ + + D +QS+ + T I       ++ + F
Sbjct:  158 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 453          
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750])

HSP 1 Score: 99.7525 bits (247), Expect = 7.387e-21
Identity = 91/321 (28.35%), Postives = 140/321 (43.61%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKI 1303
            H+  C  +G     +  V+ L +S+      K F   +   SK    +  T VACHP E  IATG   G+I +W + N   K+  VY   HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I +        T+ E   I++ D S+++ G  QG        +GL+  P                            S+ ++LNG  G LQFY L+     Y LD+  Q +  ++      G   + LV    ++ G+++AT E L   +     +  ++ + + D +QS+ + T I
Sbjct:  184 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTII 466          
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750])

HSP 1 Score: 97.8265 bits (242), Expect = 2.917e-20
Identity = 90/318 (28.30%), Postives = 137/318 (43.08%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKI 1303
            H+  C  +G     +  V+ L +S+      KS N            T VACHP E  IATG   G+I +W + N   K+  VY   HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I +        T+ E   I++ D S+++ G  QG        +GL+  P                            S+ ++LNG  G LQFY L+     Y LD+  Q +  ++      G   + LV    ++ G+++AT E L   +     +  ++ + + D +QS+ + T I
Sbjct:  121 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKSNNI----------FTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTII 390          
BLAST of WD repeat-containing protein 75 vs. Ensembl Mouse
Match: Wdr75 (WD repeat domain 75 [Source:MGI Symbol;Acc:MGI:1920924])

HSP 1 Score: 97.0561 bits (240), Expect = 3.775e-20
Identity = 92/330 (27.88%), Postives = 150/330 (45.45%), Query Frame = 2
Query:  377 DKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKV----IKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFH 1345
            +++ K IAF  +   +  V +  +SV      K+ N+ +     K++  +  T VACHP E  IA+G   GKI +W + ++  K  +T  HWH   +  L F+  G  L SGG E VLV W       +K +   PRL S IE I   V    + F  + SDN I ++  H+     +D+ S +IQ  L     +S    ++P             +  ++LNG  G LQFY L      Y LD+  Q +  +       G  Q +L   +  C G ++AT E     + ++  Q  ++++ +S   Q + + TKI M     ++ + F+
Sbjct:  154 NRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWR---DGSEKNKEFLPRLGSSIEHIS--VSPAGDLFCTSHSDNKITVI--HRN----LDA-SAVIQG-LVKDRSISTGLMVDPR------------TKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDE------GLTQTELTKAAFGCSGTWLATVEQRQENENELELQ--MKLWNYSKKTQGFVLNTKIAMPHDDHITALCFN 450          
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q6DFC6|WDR75_XENLA (WD repeat-containing protein 75 OS=Xenopus laevis OX=8355 GN=wdr75 PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.745e-24
Identity = 95/332 (28.61%), Postives = 152/332 (45.78%), Query Frame = 2
Query:  392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDN 1357
            H+  C  +G     +  V+ + +S+      KSF + +   SK    +  T VACHPSE  IATG   G+I +W + N   +  +T  HWH  S+  L FS  G  L SGG E VLV+W +   E   K+   PRL + IE I   V  +   +  + +DN I I+             SG+IQ              L    +++   + P+ S+ ++LNG  G LQFY L      Y LD+  Q +  ++      G   + LV  + S+ GR++AT E L   +  M  +  ++++ + D +QS+ + T I+      ++ + F    N
Sbjct:  156 HLPKCTAIGRQCLYVASVKGVHLSIYYFKTKKSFRFSLKATSKKGANNIFTVVACHPSEDCIATGHMDGRIRLWRNFNHKKEYTYTSLHWHHDSVMDLAFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHIS--VSPHGTLYCTSHTDNKISIIDTSL-------KVSGIIQG------------LLKGTVVKTGLIVDPR-SNALVLNGKPGHLQFYSLLNDRHLYNLDIVQQEFIHQA------GLQYMDLVKASFSSTGRWLATVEELQGGEDSMDLEMQMKLWEYQDKSQSFVLNTTINRPHEDHITSLCFRDEGN 456          
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q7ZVR1|WDR75_DANRE (WD repeat-containing protein 75 OS=Danio rerio OX=7955 GN=wdr75 PE=2 SV=2)

HSP 1 Score: 102.834 bits (255), Expect = 3.963e-21
Identity = 90/333 (27.03%), Postives = 150/333 (45.05%), Query Frame = 2
Query:  398 AFCAKLGIMGIVENLTVSVICINDNKSFNYKVI---KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTT 1378
            AF      +    +L ++V      K++++ +    K++  +  T VACHP++  IA+G   GKI +W + N   +  ++  HWH  ++  L F+  G  L SGG E VLV+W++       K+   PRL   I  + +    + + F    SDN I I+   +  F      SGLIQ  L   + VS    ++P             S  ++LNG  G LQFY L R    Y LD+  Q +  E+      G  Q ++V       G ++AT E  G   +D+  +  L+++ + +  QS+ + T +      R++ M F   +   +  TT
Sbjct:  165 AFGRGGEFIAFSRHLQLNVYFFRKQKTYSFSLKATDKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWRNFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYG---DMSKKEFLPRLGGSISHVSA--SADGQLFCTAHSDNKISII---ESSF----KVSGLIQG-LVRGDAVSTDLMIDPR------------SKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEA------GLDQFEVVKAVFDVKGSWLATVEERGHKTSDL--EFFLKLWAFDETTQSFVLNTTVTEAHSERITSMCFSSSEETTMLVTT 464          
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q8IWA0|WDR75_HUMAN (WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 4.092e-21
Identity = 88/292 (30.14%), Postives = 130/292 (44.52%), Query Frame = 2
Query:  500 RSKVHY---LTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDH-------QGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDM---DCIHRL 1327
            R+K H     T VACHP+E  IA+G   GKI +W +     K  +T  HWH   +  L FS  G  L SGG E VLV W  +    +K +   PRL + IE I   V    + F  + SDN I I+  +       QG   +   ++GL+  P T                             ++LNG  G LQFY L      Y LD+  Q +  +       G IQ++L   +  C G ++AT E     +T++  Q  +++++++   Q + + TKI+M   DCI  L
Sbjct:  197 RNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDAT---EKNKEFLPRLGATIEHIS--VSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRT---------------------------KALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDY------GLIQIELTKAAFGCFGNWLATVEQRQEKETELELQ--MKLWMYNKKTQGFILNTKINMPHEDCITAL 448          
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q3U821|WDR75_MOUSE (WD repeat-containing protein 75 OS=Mus musculus OX=10090 GN=Wdr75 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 2.641e-19
Identity = 92/330 (27.88%), Postives = 150/330 (45.45%), Query Frame = 2
Query:  377 DKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKV----IKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFH 1345
            +++ K IAF  +   +  V +  +SV      K+ N+ +     K++  +  T VACHP E  IA+G   GKI +W + ++  K  +T  HWH   +  L F+  G  L SGG E VLV W       +K +   PRL S IE I   V    + F  + SDN I ++  H+     +D+ S +IQ  L     +S    ++P             +  ++LNG  G LQFY L      Y LD+  Q +  +       G  Q +L   +  C G ++AT E     + ++  Q  ++++ +S   Q + + TKI M     ++ + F+
Sbjct:  154 NRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWR---DGSEKNKEFLPRLGSSIEHIS--VSPAGDLFCTSHSDNKITVI--HRN----LDA-SAVIQG-LVKDRSISTGLMVDPR------------TKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDE------GLTQTELTKAAFGCSGTWLATVEQRQENENELELQ--MKLWNYSKKTQGFVLNTKIAMPHDDHITALCFN 450          
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|O13878|UTP17_SCHPO (U3 small nucleolar RNA-associated protein 17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=utp17 PE=3 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 2.756e-12
Identity = 76/269 (28.25%), Postives = 121/269 (44.98%), Query Frame = 2
Query:  557 ATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILG----DHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPK----FSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESEN-----YFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQ------MLRVFIWSDDNQSYAMETKID 1306
            A  +  GKI++  D++       + HWH   L  L ++ NGEYL SGG E VLV W+   T H++     PRL S I SI      +S+ + + L DNS+ ++       Q     I+S+     + LT     + S QL   GL    ++ P       S    NGH   +Q YDL + ST  + + A  ++ + S+N         G +    VT S  G +IAT ++   C   +  QQ       L+ + +    +++ + T+ID
Sbjct:  240 AVSDDEGKIHVINDISNEKFNPQILHWHANPLNGLSWALNGEYLLSGGQEGVLVLWQME-TSHRQ---FLPRLGSSILSI--ATSHDSDSYALHLGDNSLVVIRAVDLAEQIHVSGINSFE---SKYLTSTGPKNTSKQLQ--GLVQFSSVSPNGELLLMSSSSFNGHSVSVQEYDLTKDSTIRKFEAARYSYSSVSKNSDDATSLDNGHVGSVAVTSSRNGLYIATIDTW--CTNIIDEQQRNVKQTALKFWQFDSVQKTWVLMTRID 495          
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: V3Z1V7 (WD_REPEATS_REGION domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_236208 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 3.760e-26
Identity = 84/294 (28.57%), Postives = 145/294 (49.32%), Query Frame = 2
Query:  467 DNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP 1348
            D K+ + + + + +  Y T + CHP +P I  G+  G+I+ WW+        T YHWH L +K LEF+  G  L SGGHE VLV+W+F  +     +   PRL S I  I +C   N+ Y L +  DN+IR++ +    +  +  Y GL +  ++         Q+ P         P   S  ++ NG  G LQFY+++     + LD+ CQN+ +           QV   T ++CG+++AT E       ++S +  ++ +I++++ Q+Y + T ++      +  + F P
Sbjct:  199 DLKNGDKRTVSKDENCY-TCITCHPVQPCIVIGDELGRIHFWWNFFKKNPVETSYHWHSLPVKCLEFTQEGSNLLSGGHECVLVKWQFDSS----NRDFLPRLGSPINHI-TCSPDNTVYAL-SQDDNAIRLISN---TYSPVCFYQGLTRGHMS---------QVKPRSSTGLLFDP--LSKALVTNGRVGHLQFYNVHTDIQLFNLDITCQNYISPDSLSKDSMATQVTKATFNHCGKWLATAEYWSA--ENLSPEIRIKFWIFNEEKQTYILNTSVEFPHEEEIHWLKFRP 469          
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A2J7QYF2 (Uncharacterized protein (Fragment) OS=Cryptotermes secundus OX=105785 GN=B7P43_G13025 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 1.680e-25
Identity = 98/341 (28.74%), Postives = 166/341 (48.68%), Query Frame = 2
Query:  359 NKKLISDKTFKHIAFCAKLG---IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDN--QSYAMETKIDMDCIHRLSDMVFHP 1348
            N K   D    ++AF  + G   + GI +N+      +  + +  +K   +  +    + T VACHP E  IATG+ TG++ IWW++ TS K  + VYHWH L ++ + FS  G + +SG  E VLV+W       +K     PRL + I  +   +G +++Y  ++ SDN I+IL D Q +         +IQ   T   +      L P G+     + P+ +  ++LNG  G +QFY     +  Y +D+   N+ T+  N  I   +   +  +S NC G ++AT E     +T+M     +R+  W  DN  QS+++ T +++     ++ + F P
Sbjct:  156 NMKFRLDDHAHNVAFGGRPGGEYVAGIHKNV------LQFSDAVEWKECDKQYIGGGRWFTCVACHPEERCIATGDNTGRVLIWWNLLTSGKPTWAVYHWHALPVQAITFSQAGSHFYSGAGECVLVKWTLDKPLDRK---FLPRLPTPICHLS--MGPDNKYLAVSTSDNGIQIL-DPQLKL------ISMIQH-FTWQVEAKHGLPLFPAGI----TVDPR-TKAMVLNGRTGHVQFYSPRSTTLLYNMDITGMNYLTQERNDVI---VNTDVTKVSLNCNGHWMATVEQRDDGETNME----VRLKFWHYDNVKQSFSLNTSVELPHQGGVTALAFQP 465          
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A4Y2LXF3 (WD repeat-containing protein 75 OS=Araneus ventricosus OX=182803 GN=Wdr75_0 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 8.007e-25
Identity = 125/491 (25.46%), Postives = 223/491 (45.42%), Query Frame = 2
Query:   35 VRPIYFPEKKLFVIAHENLVEVINI-----------HHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFD----NNNKKLISDKTFKH---IAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKR--SKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNW-PTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP----VDNRYLACTTIEMEFLLFQRNIKSDIAC 1432
            VRP++  + K F+IA  + V+V +I           H   +  L+E +K  +L     S+  F V  +H E KL  +    +           N ++  + V    ++   LY        + N ++I      +   IAF ++   +  +   +++V+        + KV+ +  +    L  V CHPS+ I+ATG+  G+I +W +V  S  R ++YHWH L +  + FS  G YL+SGG E  LV+W   + E    +S  PRL +     R  + ++  + + T +DNS++I+   +     I    GL Q     H + +K+  + P GL     L    +  ++LNG  G LQFY++N     + LD++ +N+   E EN  +     VQ   I + G+++AT E     +T  S Q  L+ + +    Q++ + T + +     ++ ++F P     D      T+ +  F ++   +K DI C
Sbjct:   25 VRPLFSHDSKFFLIASGSDVKVHSIQSGECVHILRYHKTRVISLQE-NKTNHLQVFSCSDDGFVVRWDHSEGKLLQVYNLHMPASSFYIPSGDNTWFVTKKV--ENQDQYRLYSLISKPKRSENVQMIVSPVLPYENAIAFGSEGKFVASIHENSLTVV------KLDVKVVAKHLTGERTLKCVTCHPSDFILATGDDQGRILVWSNVMESPIR-SIYHWHTLPVADIVFSTEGSYLYSGGGEAALVKWNLFLDE----KSILPRLGAPFH--RLNISSDGSFVVTTHTDNSLQIINSQKIVVQMI---QGLTQG----HFQGAKTANILPTGL-----LYDPLNKALVLNGKPGHLQFYNINEDKQLFNLDISGRNFISQERENVVLN--TDVQKAAIDDKGQWLATAEFWDDGET--SPQIWLKFWEFDVSKQTFVLNTNVILPHNKEVNCILFQPRIASQDMPIAVTTSNDCRFKIW--GLKDDIRC 481          
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A4Y2LXN7 (WD repeat-containing protein 75 OS=Araneus ventricosus OX=182803 GN=Wdr75_1 PE=4 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 2.679e-24
Identity = 124/491 (25.25%), Postives = 222/491 (45.21%), Query Frame = 2
Query:   35 VRPIYFPEKKLFVIAHENLVEVINI-----------HHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFD----NNNKKLISDKTFKH---IAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKR--SKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNW-PTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP----VDNRYLACTTIEMEFLLFQRNIKSDIAC 1432
            VRP++  + K  +IA  + V+V +I           H   +  L+E +K  +L     S+  F V  +H E KL  +    +           N ++  + V    ++   LY        + N ++I      +   IAF ++   +  +   +++V+        + KV+ +  +    L  V CHPS+ I+ATG+  G+I +W +V  S  R ++YHWH L +  + FS  G YL+SGG E  LV+W   + E    +S  PRL +     R  + ++  + + T +DNS++I+   +     I    GL Q     H + +K+  + P GL     L    +  ++LNG  G LQFY++N     + LD++ +N+   E EN  +     VQ   I + G+++AT E     +T  S Q  L+ + +    Q++ + T + +     ++ ++F P     D      T+ +  F ++   +K DI C
Sbjct:   25 VRPLFSHDSKFLIIASGSDVKVHSIQSGECVHILRYHKTRVISLQE-NKTNHLQVFSCSDDGFVVRWDHSEGKLLQVYNLHMPASSFYIPSGDNTWFVTKKV--ENQDQYRLYSLISKPKRSENVQMIVSPVLPYENAIAFGSEGKFVASIHENSLTVV------KLDVKVVAKHLTGERTLKCVTCHPSDFILATGDDQGRILVWSNVMESPIR-SIYHWHTLPVADIVFSTEGSYLYSGGGEAALVKWNLFLDE----KSILPRLGAPFH--RLNISSDGSFVVTTHTDNSLQIINSQKIVVQMI---QGLTQG----HFQGAKTANILPTGL-----LYDPLNKALVLNGKPGHLQFYNINEDKQLFNLDISGRNFISQERENVVLN--TDVQKAAIDDKGQWLATAEFWDDGET--SPQIWLKFWEFDVSKQTFVLNTNVILPHNKEVNCILFQPRIASQDMPIAVTTSNDCRFKIW--GLKDDIRC 481          
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A482W0X1 (WD repeat-containing protein 75 (Fragment) OS=Asbolus verrucosus OX=1661398 GN=BDFB_003221 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 1.697e-23
Identity = 85/316 (26.90%), Postives = 152/316 (48.10%), Query Frame = 2
Query:  422 MGIVENLTVSVICIND-NKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDD--NQSYAMETKIDMDCIHRLSDMVFHPVDNR 1360
              +++   ++++  +D +K+  Y++       + T +ACH    I+ TG+ TG++ +W  + T      V+HWH L ++ L FS  G Y +SGG E VLVRW+      KK     PRL S I  +   V  N+ +  I  +DN++RI+         +D+ S LIQ  L + +       L+P             +  +++NG+ G++QFY  +  S  Y +D+  QN  +   N  I    QV  + ++  G ++AT E     + D      LR+  W  D   Q++ + T ++    + ++ ++F P+DN+
Sbjct:  159 FAVIQKNILNIVPFDDFSKTHTYRI---ENSRHFTCIACHSDREIVLTGDQTGRVVVWQKLFTRKPSQAVFHWHTLPVQCLSFSVAGSYFYSGGLESVLVRWQLDNHFEKK---FLPRLPSTIAQV--AVSPNNTFIAIATNDNAVRIVD------SRLDNVS-LIQH-LVIGDNFQSGIVLDPR------------TKALVMNGNVGQIQFYSPSDNSLLYNVDIVGQNKISNERNCSIEN-TQVSKIAMTRDGLWMATVE----IRQDPEFSPELRLKFWYFDLEKQNFRLNTSVESPHENHINSILFQPMDNK 441          
BLAST of WD repeat-containing protein 75 vs. Ensembl Cavefish
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:103024989])

HSP 1 Score: 88.5817 bits (218), Expect = 1.306e-17
Identity = 77/287 (26.83%), Postives = 124/287 (43.21%), Query Frame = 2
Query:  497 KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP 1348
            K+   +  T VACHP +  IATG   GKI +W + N   +  ++  HWH  ++ +L F+  G +L SGG E VLV+W     E   K+   PRL   I  I   V ++ + +  + SDN I I+      F       GL++  +     +                     +  +++NG  G LQFY L +    Y LD+  Q +  E       G  Q +++       G ++AT E  G    D   +  L+++ +++  QS  + T I      R++ M F P
Sbjct:  201 KKGAKNAFTCVACHPKDDCIATGHEDGKIRLWRNFNQKKEYTYSTQHWHHNAVSSLCFTPEGMHLLSGGVESVLVQWH---CEEVNKKDFLPRLGGAISHI--AVSSDGQMYCTSHSDNKINII---HCSFKLSAVIQGLVKGNIWTDLVIDSR------------------TKALVMNGRPGHLQFYSLQQDKQLYSLDIVQQEYIYEE------GLDQFEVMKAVFDVRGNWLATVEERG---RDSDLEFALKLWGFNESAQSLELNTTITAAHQDRITSMCFSP 452          
BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478])

HSP 1 Score: 47.7506 bits (112), Expect = 6.457e-6
Identity = 39/129 (30.23%), Postives = 54/129 (41.86%), Query Frame = 2
Query:  443 TVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKR---------FTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRS 802
            T SV C+++N S          +  L  V C    P I  G        + D+   LKR         F+ YHWH   +  L +S  G  L +GG + VLV+W     EHK      PRL + I S+ +
Sbjct:  191 TRSVKCMSNNDSLR-------GLTSLWLVHCRVINPAIRVG--------FLDLKLKLKRNFWHKKEYTFSTYHWHSEGVSDLAYSAEGTCLHTGGPKAVLVQWRHCPEEHK---DFLPRLGAPISSVST 301          
BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478])

HSP 1 Score: 48.1358 bits (113), Expect = 8.416e-6
Identity = 39/129 (30.23%), Postives = 54/129 (41.86%), Query Frame = 2
Query:  443 TVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKR---------FTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRS 802
            T SV C+++N S          +  L  V C    P I  G        + D+   LKR         F+ YHWH   +  L +S  G  L +GG + VLV+W     EHK      PRL + I S+ +
Sbjct:  204 TRSVKCMSNNDSLR-------GLTSLWLVHCRVINPAIRVG--------FLDLKLKLKRNFWHKKEYTFSTYHWHSEGVSDLAYSAEGTCLHTGGPKAVLVQWRHCPEEHK---DFLPRLGAPISSVST 314          
BLAST of WD repeat-containing protein 75 vs. Ensembl Medaka
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:101161765])

HSP 1 Score: 92.8189 bits (229), Expect = 6.863e-19
Identity = 83/317 (26.18%), Postives = 139/317 (43.85%), Query Frame = 2
Query:  431 VENLTVSVICINDNKSFNY---KVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS--NCGRFIATCESLGVCKTDMSGQQMLRVFIWS--DDNQSYAMETKIDMDCIHRLSDMVFHPVDN 1357
             + L + V      KS+++   K  ++   +  T + CHP+E  IA+G   GKI +W + N   +  ++  HWH  ++ +L F+  G  L SGG E VLV+W ++    + ++   PRL   I  I   V  +   F  + SDN I I+             S +IQ  L   +++     + P             S  ++LNG  G LQFY L R    Y LD+  Q +  ES      G  Q ++V  +    G ++AT E     +   + +  L + +W+  D  QS+ + T I      +++ + F  V +
Sbjct:  176 AKPLQLEVYFFKKQKSYSFFLKKDNQKGGKNTFTCITCHPTEDCIASGHEDGKIRLWRNFNHRKEYTYSTLHWHHSAVSSLRFTPEGTNLLSGGVESVLVQWRYN---QESQRDFLPRLGGAITHIS--VSPDGALFCTSHSDNKITIIQS-------CVKVSAVIQG-LVKGDRIRTDLMIEPR------------SKALVLNGKPGHLQFYSLQRDKLLYNLDIVQQEYIHES------GLEQFEVVMAAFDASGSWLATVEE----RKQKAPELELNLKLWALDDQKQSFVLNTTISAPHEAQITALCFPHVSD 457          
BLAST of WD repeat-containing protein 75 vs. Planmine SMEST
Match: SMESG000006113.1 (SMESG000006113.1)

HSP 1 Score: 1541.55 bits (3990), Expect = 0.000e+0
Identity = 762/773 (98.58%), Postives = 768/773 (99.35%), Query Frame = 2
Query:    2 MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTTIEMEFLLFQRNIKSDIACWDMSNSVDLEEVLYRFQIKMENINSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDLVESNTKPVFAVQLETXXXXXXXXXXXXXXXNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLIDSQGAIEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI 2320
            MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGI+GIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWS+DNQSY +ETKIDMDCIHRLSDMVFHPVDNRYLACTTIEME LLFQRNI SDI CWDMSNSVDLEEVLYRFQIKMEN+NSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDL+ESNTKPVFAVQLETLVEDLDMKDEDKKLLNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLI+SQG IEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI
Sbjct:    1 MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGIIGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSEDNQSYELETKIDMDCIHRLSDMVFHPVDNRYLACTTIEMELLLFQRNINSDIVCWDMSNSVDLEEVLYRFQIKMENVNSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDLIESNTKPVFAVQLETLVEDLDMKDEDKKLLNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLINSQGVIEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI 773          
The following BLAST results are available for this feature:
BLAST of WD repeat-containing protein 75 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
WDR758.521e-2230.14WD repeat domain 75 [Source:HGNC Symbol;Acc:HGNC:2... [more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WD repeat-containing protein 75 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
l(2)052872.440e-1929.00gene:FBgn0284251 transcript:FBtr0114615[more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
wdr755.250e-2227.03WD repeat domain 75 [Source:NCBI gene;Acc:368478][more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
htr1a3.293e-2127.545-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
htr1a3.869e-2127.545-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
htr1a4.032e-2127.545-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
htr1a7.387e-2128.355-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
htr1a2.917e-2028.305-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Wdr753.775e-2027.88WD repeat domain 75 [Source:MGI Symbol;Acc:MGI:192... [more]
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BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6DFC6|WDR75_XENLA3.745e-2428.61WD repeat-containing protein 75 OS=Xenopus laevis ... [more]
sp|Q7ZVR1|WDR75_DANRE3.963e-2127.03WD repeat-containing protein 75 OS=Danio rerio OX=... [more]
sp|Q8IWA0|WDR75_HUMAN4.092e-2130.14WD repeat-containing protein 75 OS=Homo sapiens OX... [more]
sp|Q3U821|WDR75_MOUSE2.641e-1927.88WD repeat-containing protein 75 OS=Mus musculus OX... [more]
sp|O13878|UTP17_SCHPO2.756e-1228.25U3 small nucleolar RNA-associated protein 17 OS=Sc... [more]
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BLAST of WD repeat-containing protein 75 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V3Z1V73.760e-2628.57WD_REPEATS_REGION domain-containing protein OS=Lot... [more]
A0A2J7QYF21.680e-2528.74Uncharacterized protein (Fragment) OS=Cryptotermes... [more]
A0A4Y2LXF38.007e-2525.46WD repeat-containing protein 75 OS=Araneus ventric... [more]
A0A4Y2LXN72.679e-2425.25WD repeat-containing protein 75 OS=Araneus ventric... [more]
A0A482W0X11.697e-2326.90WD repeat-containing protein 75 (Fragment) OS=Asbo... [more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
wdr751.306e-1726.83WD repeat domain 75 [Source:NCBI gene;Acc:10302498... [more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
wdr756.457e-630.23WD repeat domain 75 [Source:NCBI gene;Acc:368478][more]
wdr758.416e-630.23WD repeat domain 75 [Source:NCBI gene;Acc:368478][more]
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BLAST of WD repeat-containing protein 75 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WD repeat-containing protein 75 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WD repeat-containing protein 75 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
wdr756.863e-1926.18WD repeat domain 75 [Source:NCBI gene;Acc:10116176... [more]
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BLAST of WD repeat-containing protein 75 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000006113.10.000e+098.58SMESG000006113.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032876 ID=SMED30032876|Name=WD repeat-containing protein 75|organism=Schmidtea mediterranea sexual|type=transcript|length=2453bp
CATGGTTGTAACTGTCAGTAAAAATTTATTATTCGTACGTCCTATATATT
TTCCTGAAAAAAAGTTGTTTGTTATTGCACATGAAAATTTAGTGGAAGTT
ATTAATATACACCATAATATAATTTGGAAATTAGAAGAAAAATCAAAAAT
TAAAAATTTAGATTACTGTGATATATCTGAAGCTAAATTTTATGTCGCAC
TTGAACATGGTGAAATTAAACTTTGTGATATTAACAAACAAGAAGTAAAC
GTTGTAATTCGACTGGAAAATGAAATTCAAAATGTATTTTATTTCAACCG
TGATGTTATAATTGTGGAGAAAGAATCAATAAATTTATACTATGGTTTCG
ATAATAACAATAAGAAACTAATTTCCGATAAAACATTTAAGCATATTGCG
TTTTGTGCAAAATTAGGTATTATGGGAATAGTTGAAAATTTGACTGTATC
TGTAATATGCATAAATGATAATAAGTCCTTTAATTATAAAGTCATCAAAC
GCAGTAAAGTTCATTATTTAACAGCTGTTGCATGTCATCCAAGTGAACCT
ATTATTGCTACTGGAGAAACCACCGGAAAGATATACATTTGGTGGGATGT
GAACACTTCTTTAAAACGATTCACTGTTTACCATTGGCACTTTCTCTCAT
TGAAAACCTTGGAATTTAGCTACAATGGGGAATATTTATTCAGTGGTGGC
CATGAGCAAGTTTTAGTGAGATGGGAATTTTCAGTGACAGAACATAAAAA
GAAACAATCTTGCTACCCTCGGCTTGAATCGGACATCGAATCTATCAGAT
CATGTGTCGGTACGAATTCCGAATATTTCCTGATCACATTGTCCGACAAT
TCCATTAGAATTCTCGGCGACCACCAGGGTAGATTCGGCGAAATCGATTC
TTATTCTGGTTTGATCCAACGACCTCTCACTCTTCACAATAAAGTCTCAA
AATCGTGCCAATTAAATCCAGTCGGGCTTAGGAGCTGTTTCAATTTGCCG
CCGAAATTCAGTTCATGCGTCTTACTGAATGGACATGAAGGCAAGCTGCA
ATTTTACGACTTGAATCGACGCTCGACCGAATATCAATTAGATGTTGCTT
GTCAGAACTGGCCGACTGAATCGGAAAACTATTTTATCCCAGGATTTATT
CAAGTTCAATTAGTGACCATCTCAAATTGCGGCCGATTCATTGCTACATG
TGAAAGTTTAGGGGTGTGCAAAACGGACATGAGTGGCCAACAAATGTTGA
GAGTATTCATTTGGAGTGATGATAATCAGAGCTATGCAATGGAAACGAAG
ATAGACATGGACTGTATTCACAGATTATCTGACATGGTTTTCCACCCAGT
TGATAACCGTTACCTCGCCTGCACGACCATCGAAATGGAGTTCCTATTGT
TCCAACGGAATATCAAAAGTGATATCGCCTGTTGGGATATGTCTAATTCA
GTCGATTTAGAAGAAGTGCTTTATCGGTTTCAAATAAAAATGGAAAATAT
CAATTCTAAAGCAAGAATGGTTACAGTAGAAAAGCAATCTAGAAAAGGTG
ATGGCCTATTGGTTGTTACAAAATGCGATTGTATAGTCTTTTATCACTGG
AGTGATTTGGTAGAGTCAAACACCAAACCGGTGTTTGCAGTTCAATTGGA
AACATTGGTAGAGGACCTTGATATGAAAGATGAAGACAAGAAACTGCTGA
ATTCCACAATATCATCGGTAGCTGTATTCAATCATGACGTCGCTTTAAAT
ACGTACCGAATCATATTGGGTCTTCCTACAGGGCTAATTGTTATAGAGAT
GCTTATCGATTCCCAGGGGGCAATTGAATATAAAGCAATCGCTGGTGCCA
TTTCCAAATTCGGCGTTAAAAGTTTGAAGTCTTATCCAGTTAGTTTGGAA
TCCAATTCGCAAGTTGCAGTTCTCTTTGAGAATTCTGATCATTTGACAAT
AATATCTGTGTGGAATGACGCTTCAGTAAACAATAAAATAGTTTCGGTTC
CAGCTCTAGATGATGTTGCGTGGGTTCCAGTGAATGGTCAAAATGACAAT
TGGGTTCTCGTAGGAATAAGGAACGATAGCAGCATGAGATCGATTGTGGT
TTGTGATGATGAAGCCCCTCATTTCACTCAGACGAATGCCATTGAAATTA
AACAGGAAACCAAGAACTTACTTTCAAGTGTTGAGGAAATTCACCAATTG
CCCAAAAAGGAGAAAACTATTAGAAGGAATTTACATAATCGTTTGGACAG
ATCCTTTTTGTTATACGATCCGATATCGTGTCCCAGCGCAACTCTCATTT
TGAATTCACTATACGCAATTTAATAAATATTATTTCCATGCATTTCATTA
TGTTGATCAGATTTTTATGCTTGTTTGATTAAATAGGTGTGACCATTATA
TCATAAATATATTTTAGACAAAAATTCTCTAGTGCTGGTGATCTTCCTAC
GCG
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protein sequence of SMED30032876-orf-1

>SMED30032876-orf-1 ID=SMED30032876-orf-1|Name=SMED30032876-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=774bp
MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKI
KNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNR
DVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGIMGIVENLTVS
VICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDV
NTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKK
KQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDS
YSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQ
FYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATC
ESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPV
DNRYLACTTIEMEFLLFQRNIKSDIACWDMSNSVDLEEVLYRFQIKMENI
NSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDLVESNTKPVFAVQLE
TLVEDLDMKDEDKKLLNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEM
LIDSQGAIEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTI
ISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVV
CDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDR
SFLLYDPISCPSATLILNSLYAI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0005515protein binding
GO:0005185neurohypophyseal hormone activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR036322WD40_repeat_dom_sf
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR017986WD40_repeat_dom
IPR022423Neurohypophysial_hormone_CS
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005634nucleus
GO:0005730nucleolus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 201..533
e-value: 6.0E-7
score: 30.5
NoneNo IPR availablePANTHERPTHR44215FAMILY NOT NAMEDcoord: 37..529
IPR017986WD40-repeat-containing domainPROSITEPS50294WD_REPEATS_REGIONcoord: 166..251
score: 9.072
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 171..476
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 18..197