WD repeat-containing protein 75
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032876 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of WD repeat-containing protein 75 vs. Ensembl Human
Match: WDR75 (WD repeat domain 75 [Source:HGNC Symbol;Acc:HGNC:25725]) HSP 1 Score: 102.834 bits (255), Expect = 8.521e-22 Identity = 88/292 (30.14%), Postives = 130/292 (44.52%), Query Frame = 2 Query: 500 RSKVHY---LTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDH-------QGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDM---DCIHRL 1327 R+K H T VACHP+E IA+G GKI +W + K +T HWH + L FS G L SGG E VLV W + +K + PRL + IE I V + F + SDN I I+ + QG + ++GL+ P T ++LNG G LQFY L Y LD+ Q + + G IQ++L + C G ++AT E +T++ Q +++++++ Q + + TKI+M DCI L Sbjct: 197 RNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDAT---EKNKEFLPRLGATIEHIS--VSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRT---------------------------KALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDY------GLIQIELTKAAFGCFGNWLATVEQRQEKETELELQ--MKLWMYNKKTQGFILNTKINMPHEDCITAL 448
BLAST of WD repeat-containing protein 75 vs. Ensembl Fly
Match: l(2)05287 (gene:FBgn0284251 transcript:FBtr0114615) HSP 1 Score: 94.3597 bits (233), Expect = 2.440e-19 Identity = 87/300 (29.00%), Postives = 139/300 (46.33%), Query Frame = 2 Query: 497 KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRF-TVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIW--SDDNQSYAMETKIDMDCIHRLSDMVFH---PVDNRYLACTT 1378 K +K H +T V P E + AT ++ G+I++W D T++HWH + +L FS +G ++SGGHE VLV+W + ++K PR+ S I I V ++E L+ DN+I+++ G + +Q T K P+GLR L P+ ++ V LNG G LQFY +S Y L V N E N+ I ++ + ++AT G D+ +R+ W ++ QSY + T+I++ + ++F VDN L C T Sbjct: 197 KSAKQHTITCVKMSPCEMVAATADSEGQIFVWRDFEKKDSMTNTLFHWHHTEVTSLAFSPSGVSIYSGGHECVLVKWTVASPGYRK---YLPRMSSVIRHI--VVSDDNENVLVCTEDNAIQLIS------GSDNIIKSTVQH-FTYETKDKTGQSKFPLGLR----LNPRTNTLV-LNGRSGHLQFYSAYTKSLLYNLRVVDTNVHNEEANHII---YNTRITRAAFNINWMAT----GEVYNDLVNFAEVRLKFWHYNERLQSYILNTEIELPHENGFKAIIFSNQFQVDN--LRCAT 470
BLAST of WD repeat-containing protein 75 vs. Ensembl Zebrafish
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478]) HSP 1 Score: 102.834 bits (255), Expect = 5.250e-22 Identity = 90/333 (27.03%), Postives = 150/333 (45.05%), Query Frame = 2 Query: 398 AFCAKLGIMGIVENLTVSVICINDNKSFNYKVI---KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTT 1378 AF + +L ++V K++++ + K++ + T VACHP++ IA+G GKI +W + N + ++ HWH ++ L F+ G L SGG E VLV+W++ K+ PRL I + + + + F SDN I I+ + F SGLIQ L + VS ++P S ++LNG G LQFY L R Y LD+ Q + E+ G Q ++V G ++AT E G +D+ + L+++ + + QS+ + T + R++ M F + + TT Sbjct: 165 AFGRGGEFIAFSRHLQLNVYFFRKQKTYSFSLKATDKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWRNFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYG---DMSKKEFLPRLGGSISHVSA--SADGQLFCTAHSDNKISII---ESSF----KVSGLIQG-LVRGDAVSTDLMIDPR------------SKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEA------GLDQFEVVKAVFDVKGSWLATVEERGHKTSDL--EFFLKLWAFDETTQSFVLNTTVTEAHSERITSMCFSSSEETTMLVTT 464
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750]) HSP 1 Score: 100.908 bits (250), Expect = 3.293e-21 Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342 H+ C +G + V+ L +S+ K F + SK + T VACHP E IATG G+I +W + N K+ VY HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I + T+ E I++ D S+++ G QG +GL+ P S+ ++LNG G LQFY L+ Y LD+ Q + ++ G + LV ++ G+++AT E L + + ++ + + D +QS+ + T I ++ + F Sbjct: 138 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 433
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750]) HSP 1 Score: 100.523 bits (249), Expect = 3.869e-21 Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342 H+ C +G + V+ L +S+ K F + SK + T VACHP E IATG G+I +W + N K+ VY HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I + T+ E I++ D S+++ G QG +GL+ P S+ ++LNG G LQFY L+ Y LD+ Q + ++ G + LV ++ G+++AT E L + + ++ + + D +QS+ + T I ++ + F Sbjct: 155 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 450
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750]) HSP 1 Score: 100.523 bits (249), Expect = 4.032e-21 Identity = 92/334 (27.54%), Postives = 144/334 (43.11%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVF 1342 H+ C +G + V+ L +S+ K F + SK + T VACHP E IATG G+I +W + N K+ VY HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I + T+ E I++ D S+++ G QG +GL+ P S+ ++LNG G LQFY L+ Y LD+ Q + ++ G + LV ++ G+++AT E L + + ++ + + D +QS+ + T I ++ + F Sbjct: 158 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTIISRPHEDHITSLCF 453
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750]) HSP 1 Score: 99.7525 bits (247), Expect = 7.387e-21 Identity = 91/321 (28.35%), Postives = 140/321 (43.61%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKI 1303 H+ C +G + V+ L +S+ K F + SK + T VACHP E IATG G+I +W + N K+ VY HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I + T+ E I++ D S+++ G QG +GL+ P S+ ++LNG G LQFY L+ Y LD+ Q + ++ G + LV ++ G+++AT E L + + ++ + + D +QS+ + T I Sbjct: 184 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKCFRLPLKATSKKGANNIFTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTII 466
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Match: htr1a (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:Xenbase;Acc:XB-GENE-984750]) HSP 1 Score: 97.8265 bits (242), Expect = 2.917e-20 Identity = 90/318 (28.30%), Postives = 137/318 (43.08%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVY---HWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVG-----TNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVT--ISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKI 1303 H+ C +G + V+ L +S+ KS N T VACHP E IATG G+I +W + N K+ VY HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I + T+ E I++ D S+++ G QG +GL+ P S+ ++LNG G LQFY L+ Y LD+ Q + ++ G + LV ++ G+++AT E L + + ++ + + D +QS+ + T I Sbjct: 121 HLPKCTAIGRQCLYVASVKGLHLSIYYFKTKKSNNI----------FTVVACHPKEDCIATGHMDGRIRLWRNFNH--KQGYVYSSLHWHHDSVMDLTFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHISTSPHGTLYCTSHEDNKISIIDTSLKVSGIIQGLLKGTVVKTGLVVDPR---------------------------SNALVLNGKPGHLQFYSLHNDRHLYNLDIVQQEFIHQA------GLQYMDLVKALFNSTGKWLATVEELQGGEDSRDLEMQMKFWEYQDKSQSFVLNTII 390
BLAST of WD repeat-containing protein 75 vs. Ensembl Mouse
Match: Wdr75 (WD repeat domain 75 [Source:MGI Symbol;Acc:MGI:1920924]) HSP 1 Score: 97.0561 bits (240), Expect = 3.775e-20 Identity = 92/330 (27.88%), Postives = 150/330 (45.45%), Query Frame = 2 Query: 377 DKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKV----IKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFH 1345 +++ K IAF + + V + +SV K+ N+ + K++ + T VACHP E IA+G GKI +W + ++ K +T HWH + L F+ G L SGG E VLV W +K + PRL S IE I V + F + SDN I ++ H+ +D+ S +IQ L +S ++P + ++LNG G LQFY L Y LD+ Q + + G Q +L + C G ++AT E + ++ Q ++++ +S Q + + TKI M ++ + F+ Sbjct: 154 NRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWR---DGSEKNKEFLPRLGSSIEHIS--VSPAGDLFCTSHSDNKITVI--HRN----LDA-SAVIQG-LVKDRSISTGLMVDPR------------TKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDE------GLTQTELTKAAFGCSGTWLATVEQRQENENELELQ--MKLWNYSKKTQGFVLNTKIAMPHDDHITALCFN 450
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q6DFC6|WDR75_XENLA (WD repeat-containing protein 75 OS=Xenopus laevis OX=8355 GN=wdr75 PE=2 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 3.745e-24 Identity = 95/332 (28.61%), Postives = 152/332 (45.78%), Query Frame = 2 Query: 392 HIAFCAKLG----IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDN 1357 H+ C +G + V+ + +S+ KSF + + SK + T VACHPSE IATG G+I +W + N + +T HWH S+ L FS G L SGG E VLV+W + E K+ PRL + IE I V + + + +DN I I+ SG+IQ L +++ + P+ S+ ++LNG G LQFY L Y LD+ Q + ++ G + LV + S+ GR++AT E L + M + ++++ + D +QS+ + T I+ ++ + F N Sbjct: 156 HLPKCTAIGRQCLYVASVKGVHLSIYYFKTKKSFRFSLKATSKKGANNIFTVVACHPSEDCIATGHMDGRIRLWRNFNHKKEYTYTSLHWHHDSVMDLAFSAQGTKLLSGGVESVLVQWPYGSEE---KKEFLPRLGAAIEHIS--VSPHGTLYCTSHTDNKISIIDTSL-------KVSGIIQG------------LLKGTVVKTGLIVDPR-SNALVLNGKPGHLQFYSLLNDRHLYNLDIVQQEFIHQA------GLQYMDLVKASFSSTGRWLATVEELQGGEDSMDLEMQMKLWEYQDKSQSFVLNTTINRPHEDHITSLCFRDEGN 456
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q7ZVR1|WDR75_DANRE (WD repeat-containing protein 75 OS=Danio rerio OX=7955 GN=wdr75 PE=2 SV=2) HSP 1 Score: 102.834 bits (255), Expect = 3.963e-21 Identity = 90/333 (27.03%), Postives = 150/333 (45.05%), Query Frame = 2 Query: 398 AFCAKLGIMGIVENLTVSVICINDNKSFNYKVI---KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTT 1378 AF + +L ++V K++++ + K++ + T VACHP++ IA+G GKI +W + N + ++ HWH ++ L F+ G L SGG E VLV+W++ K+ PRL I + + + + F SDN I I+ + F SGLIQ L + VS ++P S ++LNG G LQFY L R Y LD+ Q + E+ G Q ++V G ++AT E G +D+ + L+++ + + QS+ + T + R++ M F + + TT Sbjct: 165 AFGRGGEFIAFSRHLQLNVYFFRKQKTYSFSLKATDKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWRNFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYG---DMSKKEFLPRLGGSISHVSA--SADGQLFCTAHSDNKISII---ESSF----KVSGLIQG-LVRGDAVSTDLMIDPR------------SKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEA------GLDQFEVVKAVFDVKGSWLATVEERGHKTSDL--EFFLKLWAFDETTQSFVLNTTVTEAHSERITSMCFSSSEETTMLVTT 464
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q8IWA0|WDR75_HUMAN (WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1) HSP 1 Score: 102.834 bits (255), Expect = 4.092e-21 Identity = 88/292 (30.14%), Postives = 130/292 (44.52%), Query Frame = 2 Query: 500 RSKVHY---LTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDH-------QGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDM---DCIHRL 1327 R+K H T VACHP+E IA+G GKI +W + K +T HWH + L FS G L SGG E VLV W + +K + PRL + IE I V + F + SDN I I+ + QG + ++GL+ P T ++LNG G LQFY L Y LD+ Q + + G IQ++L + C G ++AT E +T++ Q +++++++ Q + + TKI+M DCI L Sbjct: 197 RNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDAT---EKNKEFLPRLGATIEHIS--VSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRT---------------------------KALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDY------GLIQIELTKAAFGCFGNWLATVEQRQEKETELELQ--MKLWMYNKKTQGFILNTKINMPHEDCITAL 448
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|Q3U821|WDR75_MOUSE (WD repeat-containing protein 75 OS=Mus musculus OX=10090 GN=Wdr75 PE=1 SV=1) HSP 1 Score: 97.0561 bits (240), Expect = 2.641e-19 Identity = 92/330 (27.88%), Postives = 150/330 (45.45%), Query Frame = 2 Query: 377 DKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKV----IKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFH 1345 +++ K IAF + + V + +SV K+ N+ + K++ + T VACHP E IA+G GKI +W + ++ K +T HWH + L F+ G L SGG E VLV W +K + PRL S IE I V + F + SDN I ++ H+ +D+ S +IQ L +S ++P + ++LNG G LQFY L Y LD+ Q + + G Q +L + C G ++AT E + ++ Q ++++ +S Q + + TKI M ++ + F+ Sbjct: 154 NRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWR---DGSEKNKEFLPRLGSSIEHIS--VSPAGDLFCTSHSDNKITVI--HRN----LDA-SAVIQG-LVKDRSISTGLMVDPR------------TKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDE------GLTQTELTKAAFGCSGTWLATVEQRQENENELELQ--MKLWNYSKKTQGFVLNTKIAMPHDDHITALCFN 450
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Match: sp|O13878|UTP17_SCHPO (U3 small nucleolar RNA-associated protein 17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=utp17 PE=3 SV=3) HSP 1 Score: 74.3294 bits (181), Expect = 2.756e-12 Identity = 76/269 (28.25%), Postives = 121/269 (44.98%), Query Frame = 2 Query: 557 ATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILG----DHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPK----FSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESEN-----YFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQ------MLRVFIWSDDNQSYAMETKID 1306 A + GKI++ D++ + HWH L L ++ NGEYL SGG E VLV W+ T H++ PRL S I SI +S+ + + L DNS+ ++ Q I+S+ + LT + S QL GL ++ P S NGH +Q YDL + ST + + A ++ + S+N G + VT S G +IAT ++ C + QQ L+ + + +++ + T+ID Sbjct: 240 AVSDDEGKIHVINDISNEKFNPQILHWHANPLNGLSWALNGEYLLSGGQEGVLVLWQME-TSHRQ---FLPRLGSSILSI--ATSHDSDSYALHLGDNSLVVIRAVDLAEQIHVSGINSFE---SKYLTSTGPKNTSKQLQ--GLVQFSSVSPNGELLLMSSSSFNGHSVSVQEYDLTKDSTIRKFEAARYSYSSVSKNSDDATSLDNGHVGSVAVTSSRNGLYIATIDTW--CTNIIDEQQRNVKQTALKFWQFDSVQKTWVLMTRID 495
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: V3Z1V7 (WD_REPEATS_REGION domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_236208 PE=4 SV=1) HSP 1 Score: 127.102 bits (318), Expect = 3.760e-26 Identity = 84/294 (28.57%), Postives = 145/294 (49.32%), Query Frame = 2 Query: 467 DNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP 1348 D K+ + + + + + Y T + CHP +P I G+ G+I+ WW+ T YHWH L +K LEF+ G L SGGHE VLV+W+F + + PRL S I I +C N+ Y L + DN+IR++ + + + Y GL + ++ Q+ P P S ++ NG G LQFY+++ + LD+ CQN+ + QV T ++CG+++AT E ++S + ++ +I++++ Q+Y + T ++ + + F P Sbjct: 199 DLKNGDKRTVSKDENCY-TCITCHPVQPCIVIGDELGRIHFWWNFFKKNPVETSYHWHSLPVKCLEFTQEGSNLLSGGHECVLVKWQFDSS----NRDFLPRLGSPINHI-TCSPDNTVYAL-SQDDNAIRLISN---TYSPVCFYQGLTRGHMS---------QVKPRSSTGLLFDP--LSKALVTNGRVGHLQFYNVHTDIQLFNLDITCQNYISPDSLSKDSMATQVTKATFNHCGKWLATAEYWSA--ENLSPEIRIKFWIFNEEKQTYILNTSVEFPHEEEIHWLKFRP 469
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A2J7QYF2 (Uncharacterized protein (Fragment) OS=Cryptotermes secundus OX=105785 GN=B7P43_G13025 PE=4 SV=1) HSP 1 Score: 124.405 bits (311), Expect = 1.680e-25 Identity = 98/341 (28.74%), Postives = 166/341 (48.68%), Query Frame = 2 Query: 359 NKKLISDKTFKHIAFCAKLG---IMGIVENLTVSVICINDNKSFNYKVIKRSKV---HYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS-NC-GRFIATCESLGVCKTDMSGQQMLRVFIWSDDN--QSYAMETKIDMDCIHRLSDMVFHP 1348 N K D ++AF + G + GI +N+ + + + +K + + + T VACHP E IATG+ TG++ IWW++ TS K + VYHWH L ++ + FS G + +SG E VLV+W +K PRL + I + +G +++Y ++ SDN I+IL D Q + +IQ T + L P G+ + P+ + ++LNG G +QFY + Y +D+ N+ T+ N I + + +S NC G ++AT E +T+M +R+ W DN QS+++ T +++ ++ + F P Sbjct: 156 NMKFRLDDHAHNVAFGGRPGGEYVAGIHKNV------LQFSDAVEWKECDKQYIGGGRWFTCVACHPEERCIATGDNTGRVLIWWNLLTSGKPTWAVYHWHALPVQAITFSQAGSHFYSGAGECVLVKWTLDKPLDRK---FLPRLPTPICHLS--MGPDNKYLAVSTSDNGIQIL-DPQLKL------ISMIQH-FTWQVEAKHGLPLFPAGI----TVDPR-TKAMVLNGRTGHVQFYSPRSTTLLYNMDITGMNYLTQERNDVI---VNTDVTKVSLNCNGHWMATVEQRDDGETNME----VRLKFWHYDNVKQSFSLNTSVELPHQGGVTALAFQP 465
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A4Y2LXF3 (WD repeat-containing protein 75 OS=Araneus ventricosus OX=182803 GN=Wdr75_0 PE=4 SV=1) HSP 1 Score: 122.479 bits (306), Expect = 8.007e-25 Identity = 125/491 (25.46%), Postives = 223/491 (45.42%), Query Frame = 2 Query: 35 VRPIYFPEKKLFVIAHENLVEVINI-----------HHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFD----NNNKKLISDKTFKH---IAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKR--SKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNW-PTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP----VDNRYLACTTIEMEFLLFQRNIKSDIAC 1432 VRP++ + K F+IA + V+V +I H + L+E +K +L S+ F V +H E KL + + N ++ + V ++ LY + N ++I + IAF ++ + + +++V+ + KV+ + + L V CHPS+ I+ATG+ G+I +W +V S R ++YHWH L + + FS G YL+SGG E LV+W + E +S PRL + R + ++ + + T +DNS++I+ + I GL Q H + +K+ + P GL L + ++LNG G LQFY++N + LD++ +N+ E EN + VQ I + G+++AT E +T S Q L+ + + Q++ + T + + ++ ++F P D T+ + F ++ +K DI C Sbjct: 25 VRPLFSHDSKFFLIASGSDVKVHSIQSGECVHILRYHKTRVISLQE-NKTNHLQVFSCSDDGFVVRWDHSEGKLLQVYNLHMPASSFYIPSGDNTWFVTKKV--ENQDQYRLYSLISKPKRSENVQMIVSPVLPYENAIAFGSEGKFVASIHENSLTVV------KLDVKVVAKHLTGERTLKCVTCHPSDFILATGDDQGRILVWSNVMESPIR-SIYHWHTLPVADIVFSTEGSYLYSGGGEAALVKWNLFLDE----KSILPRLGAPFH--RLNISSDGSFVVTTHTDNSLQIINSQKIVVQMI---QGLTQG----HFQGAKTANILPTGL-----LYDPLNKALVLNGKPGHLQFYNINEDKQLFNLDISGRNFISQERENVVLN--TDVQKAAIDDKGQWLATAEFWDDGET--SPQIWLKFWEFDVSKQTFVLNTNVILPHNKEVNCILFQPRIASQDMPIAVTTSNDCRFKIW--GLKDDIRC 481
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A4Y2LXN7 (WD repeat-containing protein 75 OS=Araneus ventricosus OX=182803 GN=Wdr75_1 PE=4 SV=1) HSP 1 Score: 120.553 bits (301), Expect = 2.679e-24 Identity = 124/491 (25.25%), Postives = 222/491 (45.21%), Query Frame = 2 Query: 35 VRPIYFPEKKLFVIAHENLVEVINI-----------HHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFD----NNNKKLISDKTFKH---IAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKR--SKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNW-PTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP----VDNRYLACTTIEMEFLLFQRNIKSDIAC 1432 VRP++ + K +IA + V+V +I H + L+E +K +L S+ F V +H E KL + + N ++ + V ++ LY + N ++I + IAF ++ + + +++V+ + KV+ + + L V CHPS+ I+ATG+ G+I +W +V S R ++YHWH L + + FS G YL+SGG E LV+W + E +S PRL + R + ++ + + T +DNS++I+ + I GL Q H + +K+ + P GL L + ++LNG G LQFY++N + LD++ +N+ E EN + VQ I + G+++AT E +T S Q L+ + + Q++ + T + + ++ ++F P D T+ + F ++ +K DI C Sbjct: 25 VRPLFSHDSKFLIIASGSDVKVHSIQSGECVHILRYHKTRVISLQE-NKTNHLQVFSCSDDGFVVRWDHSEGKLLQVYNLHMPASSFYIPSGDNTWFVTKKV--ENQDQYRLYSLISKPKRSENVQMIVSPVLPYENAIAFGSEGKFVASIHENSLTVV------KLDVKVVAKHLTGERTLKCVTCHPSDFILATGDDQGRILVWSNVMESPIR-SIYHWHTLPVADIVFSTEGSYLYSGGGEAALVKWNLFLDE----KSILPRLGAPFH--RLNISSDGSFVVTTHTDNSLQIINSQKIVVQMI---QGLTQG----HFQGAKTANILPTGL-----LYDPLNKALVLNGKPGHLQFYNINEDKQLFNLDISGRNFISQERENVVLN--TDVQKAAIDDKGQWLATAEFWDDGET--SPQIWLKFWEFDVSKQTFVLNTNVILPHNKEVNCILFQPRIASQDMPIAVTTSNDCRFKIW--GLKDDIRC 481
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Match: A0A482W0X1 (WD repeat-containing protein 75 (Fragment) OS=Asbolus verrucosus OX=1661398 GN=BDFB_003221 PE=4 SV=1) HSP 1 Score: 118.242 bits (295), Expect = 1.697e-23 Identity = 85/316 (26.90%), Postives = 152/316 (48.10%), Query Frame = 2 Query: 422 MGIVENLTVSVICIND-NKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDD--NQSYAMETKIDMDCIHRLSDMVFHPVDNR 1360 +++ ++++ +D +K+ Y++ + T +ACH I+ TG+ TG++ +W + T V+HWH L ++ L FS G Y +SGG E VLVRW+ KK PRL S I + V N+ + I +DN++RI+ +D+ S LIQ L + + L+P + +++NG+ G++QFY + S Y +D+ QN + N I QV + ++ G ++AT E + D LR+ W D Q++ + T ++ + ++ ++F P+DN+ Sbjct: 159 FAVIQKNILNIVPFDDFSKTHTYRI---ENSRHFTCIACHSDREIVLTGDQTGRVVVWQKLFTRKPSQAVFHWHTLPVQCLSFSVAGSYFYSGGLESVLVRWQLDNHFEKK---FLPRLPSTIAQV--AVSPNNTFIAIATNDNAVRIVD------SRLDNVS-LIQH-LVIGDNFQSGIVLDPR------------TKALVMNGNVGQIQFYSPSDNSLLYNVDIVGQNKISNERNCSIEN-TQVSKIAMTRDGLWMATVE----IRQDPEFSPELRLKFWYFDLEKQNFRLNTSVESPHENHINSILFQPMDNK 441
BLAST of WD repeat-containing protein 75 vs. Ensembl Cavefish
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:103024989]) HSP 1 Score: 88.5817 bits (218), Expect = 1.306e-17 Identity = 77/287 (26.83%), Postives = 124/287 (43.21%), Query Frame = 2 Query: 497 KRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLV--TISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHP 1348 K+ + T VACHP + IATG GKI +W + N + ++ HWH ++ +L F+ G +L SGG E VLV+W E K+ PRL I I V ++ + + + SDN I I+ F GL++ + + + +++NG G LQFY L + Y LD+ Q + E G Q +++ G ++AT E G D + L+++ +++ QS + T I R++ M F P Sbjct: 201 KKGAKNAFTCVACHPKDDCIATGHEDGKIRLWRNFNQKKEYTYSTQHWHHNAVSSLCFTPEGMHLLSGGVESVLVQWH---CEEVNKKDFLPRLGGAISHI--AVSSDGQMYCTSHSDNKINII---HCSFKLSAVIQGLVKGNIWTDLVIDSR------------------TKALVMNGRPGHLQFYSLQQDKQLYSLDIVQQEYIYEE------GLDQFEVMKAVFDVRGNWLATVEERG---RDSDLEFALKLWGFNESAQSLELNTTITAAHQDRITSMCFSP 452
BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478]) HSP 1 Score: 47.7506 bits (112), Expect = 6.457e-6 Identity = 39/129 (30.23%), Postives = 54/129 (41.86%), Query Frame = 2 Query: 443 TVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKR---------FTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRS 802 T SV C+++N S + L V C P I G + D+ LKR F+ YHWH + L +S G L +GG + VLV+W EHK PRL + I S+ + Sbjct: 191 TRSVKCMSNNDSLR-------GLTSLWLVHCRVINPAIRVG--------FLDLKLKLKRNFWHKKEYTFSTYHWHSEGVSDLAYSAEGTCLHTGGPKAVLVQWRHCPEEHK---DFLPRLGAPISSVST 301
BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:368478]) HSP 1 Score: 48.1358 bits (113), Expect = 8.416e-6 Identity = 39/129 (30.23%), Postives = 54/129 (41.86%), Query Frame = 2 Query: 443 TVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKR---------FTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRS 802 T SV C+++N S + L V C P I G + D+ LKR F+ YHWH + L +S G L +GG + VLV+W EHK PRL + I S+ + Sbjct: 204 TRSVKCMSNNDSLR-------GLTSLWLVHCRVINPAIRVG--------FLDLKLKLKRNFWHKKEYTFSTYHWHSEGVSDLAYSAEGTCLHTGGPKAVLVQWRHCPEEHK---DFLPRLGAPISSVST 314
BLAST of WD repeat-containing protein 75 vs. Ensembl Medaka
Match: wdr75 (WD repeat domain 75 [Source:NCBI gene;Acc:101161765]) HSP 1 Score: 92.8189 bits (229), Expect = 6.863e-19 Identity = 83/317 (26.18%), Postives = 139/317 (43.85%), Query Frame = 2 Query: 431 VENLTVSVICINDNKSFNY---KVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLK-RFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTIS--NCGRFIATCESLGVCKTDMSGQQMLRVFIWS--DDNQSYAMETKIDMDCIHRLSDMVFHPVDN 1357 + L + V KS+++ K ++ + T + CHP+E IA+G GKI +W + N + ++ HWH ++ +L F+ G L SGG E VLV+W ++ + ++ PRL I I V + F + SDN I I+ S +IQ L +++ + P S ++LNG G LQFY L R Y LD+ Q + ES G Q ++V + G ++AT E + + + L + +W+ D QS+ + T I +++ + F V + Sbjct: 176 AKPLQLEVYFFKKQKSYSFFLKKDNQKGGKNTFTCITCHPTEDCIASGHEDGKIRLWRNFNHRKEYTYSTLHWHHSAVSSLRFTPEGTNLLSGGVESVLVQWRYN---QESQRDFLPRLGGAITHIS--VSPDGALFCTSHSDNKITIIQS-------CVKVSAVIQG-LVKGDRIRTDLMIEPR------------SKALVLNGKPGHLQFYSLQRDKLLYNLDIVQQEYIHES------GLEQFEVVMAAFDASGSWLATVEE----RKQKAPELELNLKLWALDDQKQSFVLNTTISAPHEAQITALCFPHVSD 457
BLAST of WD repeat-containing protein 75 vs. Planmine SMEST
Match: SMESG000006113.1 (SMESG000006113.1) HSP 1 Score: 1541.55 bits (3990), Expect = 0.000e+0 Identity = 762/773 (98.58%), Postives = 768/773 (99.35%), Query Frame = 2 Query: 2 MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGIMGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSDDNQSYAMETKIDMDCIHRLSDMVFHPVDNRYLACTTIEMEFLLFQRNIKSDIACWDMSNSVDLEEVLYRFQIKMENINSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDLVESNTKPVFAVQLETXXXXXXXXXXXXXXXNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLIDSQGAIEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI 2320 MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGI+GIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWS+DNQSY +ETKIDMDCIHRLSDMVFHPVDNRYLACTTIEME LLFQRNI SDI CWDMSNSVDLEEVLYRFQIKMEN+NSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDL+ESNTKPVFAVQLETLVEDLDMKDEDKKLLNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLI+SQG IEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI Sbjct: 1 MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIKNLDYCDISEAKFYVALEHGEIKLCDINKQEVNVVIRLENEIQNVFYFNRDVIIVEKESINLYYGFDNNNKKLISDKTFKHIAFCAKLGIIGIVENLTVSVICINDNKSFNYKVIKRSKVHYLTAVACHPSEPIIATGETTGKIYIWWDVNTSLKRFTVYHWHFLSLKTLEFSYNGEYLFSGGHEQVLVRWEFSVTEHKKKQSCYPRLESDIESIRSCVGTNSEYFLITLSDNSIRILGDHQGRFGEIDSYSGLIQRPLTLHNKVSKSCQLNPVGLRSCFNLPPKFSSCVLLNGHEGKLQFYDLNRRSTEYQLDVACQNWPTESENYFIPGFIQVQLVTISNCGRFIATCESLGVCKTDMSGQQMLRVFIWSEDNQSYELETKIDMDCIHRLSDMVFHPVDNRYLACTTIEMELLLFQRNINSDIVCWDMSNSVDLEEVLYRFQIKMENVNSKARMVTVEKQSRKGDGLLVVTKCDCIVFYHWSDLIESNTKPVFAVQLETLVEDLDMKDEDKKLLNSTISSVAVFNHDVALNTYRIILGLPTGLIVIEMLINSQGVIEYKAIAGAISKFGVKSLKSYPVSLESNSQVAVLFENSDHLTIISVWNDASVNNKIVSVPALDDVAWVPVNGQNDNWVLVGIRNDSSMRSIVVCDDEAPHFTQTNAIEIKQETKNLLSSVEEIHQLPKKEKTIRRNLHNRLDRSFLLYDPISCPSATLILNSLYAI 773 The following BLAST results are available for this feature:
BLAST of WD repeat-containing protein 75 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of WD repeat-containing protein 75 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of WD repeat-containing protein 75 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of WD repeat-containing protein 75 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WD repeat-containing protein 75 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of WD repeat-containing protein 75 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of WD repeat-containing protein 75 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of WD repeat-containing protein 75 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of WD repeat-containing protein 75 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032876 ID=SMED30032876|Name=WD repeat-containing protein 75|organism=Schmidtea mediterranea sexual|type=transcript|length=2453bpback to top protein sequence of SMED30032876-orf-1 >SMED30032876-orf-1 ID=SMED30032876-orf-1|Name=SMED30032876-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=774bp MVVTVSKNLLFVRPIYFPEKKLFVIAHENLVEVINIHHNIIWKLEEKSKIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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