Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein)
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032865 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]) HSP 1 Score: 56.9954 bits (136), Expect = 5.104e-8 Identity = 39/148 (26.35%), Postives = 68/148 (45.95%), Query Frame = 2 Query: 974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 V+C G+ + + +Y+ Y++ + L+ +LDG P C+ + ++ MWR FDV LH +L +V+ P+ + F+ FAFV +HG W +L+ EN ++ + + L + FSP RR Sbjct: 214 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 361
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]) HSP 1 Score: 56.9954 bits (136), Expect = 5.104e-8 Identity = 39/148 (26.35%), Postives = 68/148 (45.95%), Query Frame = 2 Query: 974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 V+C G+ + + +Y+ Y++ + L+ +LDG P C+ + ++ MWR FDV LH +L +V+ P+ + F+ FAFV +HG W +L+ EN ++ + + L + FSP RR Sbjct: 214 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 361
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]) HSP 1 Score: 56.9954 bits (136), Expect = 6.787e-8 Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 G+ + + +Y+ Y++ + L+ +LDG P C+ + ++ MWR FDV LH +L +V+ P+ + F+ FAFV +HG W +L+ EN ++ + + L + FSP RR Sbjct: 288 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 427
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]) HSP 1 Score: 56.9954 bits (136), Expect = 6.787e-8 Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 G+ + + +Y+ Y++ + L+ +LDG P C+ + ++ MWR FDV LH +L +V+ P+ + F+ FAFV +HG W +L+ EN ++ + + L + FSP RR Sbjct: 288 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 427
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270]) HSP 1 Score: 56.225 bits (134), Expect = 7.365e-8 Identity = 41/149 (27.52%), Postives = 71/149 (47.65%), Query Frame = 2 Query: 974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLY-WISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 V+C G+ + + +Y+ Y++ + L+ +LDG P C+ + ++ MWR FDV LH +L +V+ P+ + F+ FAFV +HG D L+ W +L+ EN ++ + + L + FSP RR Sbjct: 142 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHG-GYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 289
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Match: hhat-1 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:G5EFT7]) HSP 1 Score: 77.7962 bits (190), Expect = 6.068e-15 Identity = 52/192 (27.08%), Postives = 90/192 (46.88%), Query Frame = 2 Query: 845 EDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 +W + +S VRIA + ++ +H+ + + + K VA G+ M GI +++ Y + + L +LD PGP C++ + LYS++WR FD L+ + K ++F PI + F + FV+ +HG N+ WI L+I E K I+ V + E S + RR++ Sbjct: 254 RNWLDCAWSGVRIAFWWWLMEASLHFLYHEAILKNAPYLYSLPKDQFVALGMAM--GIFFHLKYAVIFGLPTLFAKLDNMDPLPGPICLIRVTLYSKVWREFDRGLYQFFKTYIFIPICAPTFSLPRKIFGVFISYGFVLLWHGFYHHNIVWIGLNILALFIEMGSKAIYTIESVRKWREANLSDVAFRRIL 443
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Match: hhat-2 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:O18241]) HSP 1 Score: 69.3218 bits (168), Expect = 3.343e-12 Identity = 41/113 (36.28%), Postives = 62/113 (54.87%), Query Frame = 2 Query: 1004 GIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRP-IAKLGPF--RITRYFAAI-ACFAFVVNFHGLRRDNLYWISLSIFQYMAENI 1330 G +++ Y++ + LDGF P P CI ++LYSRMWR FD L+ +LK V+ P + K P I R A+ A F V+ +HG RR ++W++LS + + E I Sbjct: 303 GQLFHVKYVVIFGVPAFFAALDGFRPPPPPICISRVSLYSRMWRFFDNGLYQFLKYQVYIPAMRKPLPLFWSILRSLGALCAVFGVVLAWHGTRRHFIFWVTLSATELIVERI 415
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Fly
Match: rasp (gene:FBgn0024194 transcript:FBtr0073029) HSP 1 Score: 52.7582 bits (125), Expect = 6.106e-7 Identity = 83/413 (20.10%), Postives = 168/413 (40.68%), Query Frame = 2 Query: 152 DVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNN--KKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPF-TFYIFISKLLRSYTSPKMFMFGNL---LITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYM------PDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKL--VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILK 1336 D +++ E Y +++ ++ G+Y+IY L ++ K+ + QF + + S +N+ L E F+ PF ++ + +R + P++ G + + N +SS V + ++ I L K L+W++ + + M D Y +Y L + + + R S L+ A + D+ +++ Y YFP + ++ + F + +++W ++ +R A + + +HY Y+ ++ D + ++ + F G +++ Y++ Y DG P CI I YS MW+ FD L+ +L +++ + ++ A FAFV +HG L W L+ AE + K Sbjct: 6 DRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDEL--ENFGDFIVSFWPFYLLHVAVQGFIR-WKRPRLQCLGFIGVCALALSVNLDWSSMVLL---VTLIASYYIVSLLSLKFLVWLLSAGWILCINVMQKNVWWTDRVGYTEYVLVIVTMSWSVL---RGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIWWLVMQCALHY--FYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFK 405
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Zebrafish
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1]) HSP 1 Score: 59.6918 bits (143), Expect = 4.866e-9 Identity = 53/213 (24.88%), Postives = 101/213 (47.42%), Query Frame = 2 Query: 743 LEMSFYFWYFPAIIGCRLMVIKEFINNIYKP-CVIEDWKEWLFSSV-RIAAYIFIWNIVMHYCHI--------YLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIF 1345 L+++ + +Y P +M K+F I +P C + +FS + R+ + + ++H+ ++ YL ++ W + +A VQ FY + Y++ + + L+ +LDG P C+ + ++ MWR+FDV L+ WL +++ P+ ++ G FR + + F FV +HG LYW L+ + EN +F Sbjct: 224 LKLTAFCFYHPLFYNGPIMTYKDFSEQIERPLCKVSALH--VFSGILRLCVWWCLAEFMIHFMYMHAIQSNETYLEMLP-PWAMGGLALAL-VQFFY-----VKYLVLFGAVSLLVRLDGLEPPTLPRCVSIMYSFTGMWRHFDVGLYKWLIRYIYVPLGGSRHGAFR--KLLSTALAFGFVCFWHGCHDYLLYWALLNWVGVLVENAFALLF 425
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Xenopus
Match: HHAT (hedgehog acyltransferase [Source:NCBI gene;Acc:100490766]) HSP 1 Score: 58.151 bits (139), Expect = 2.002e-8 Identity = 36/141 (25.53%), Postives = 68/141 (48.23%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408 G+ + + +Y+ Y++ Y LI +LDG P C+ + ++ +WR+FDV LH +L +++ P+ ++ F FV +HG YW +L+ +AE+ K + V +++T SP R++ Sbjct: 189 GLALAQVLFFYVKYLVLYGLPALIVRLDGLDPPALPRCVSTMYSFTGIWRSFDVGLHRFLVRYIYIPLGGSQRGLHGMLLSSALTFIFVCCWHGAHEYLWYWAALNWIGLVAEHAGKKLLDIPVVQHAVDRTLSPKMHRQI 329
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681]) HSP 1 Score: 59.6918 bits (143), Expect = 5.745e-9 Identity = 50/200 (25.00%), Postives = 85/200 (42.50%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQIS 1585 G+ + + +Y+ Y++ + L+ +LDG P P C+ + ++ MWR FDV LH +L +V+ P+ + + FAFV +HG D W +L+ E+ ++ + V L + SP RL A A S + F GI + + + W V + G + YSH I+ Sbjct: 293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPW-VTLSVLGFLYCYSHVDIA 491
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681]) HSP 1 Score: 59.3066 bits (142), Expect = 6.817e-9 Identity = 37/141 (26.24%), Postives = 65/141 (46.10%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408 G+ + + +Y+ Y++ + L+ +LDG P P C+ + ++ MWR FDV LH +L +V+ P+ + + FAFV +HG D W +L+ E+ ++ + V L + SP RL Sbjct: 293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRL 433
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681]) HSP 1 Score: 59.3066 bits (142), Expect = 6.991e-9 Identity = 37/141 (26.24%), Postives = 65/141 (46.10%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408 G+ + + +Y+ Y++ + L+ +LDG P P C+ + ++ MWR FDV LH +L +V+ P+ + + FAFV +HG D W +L+ E+ ++ + V L + SP RL Sbjct: 293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRL 433
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Match: sp|Q8BMT9|HHAT_MOUSE (Protein-cysteine N-palmitoyltransferase HHAT OS=Mus musculus OX=10090 GN=Hhat PE=2 SV=1) HSP 1 Score: 59.6918 bits (143), Expect = 4.018e-8 Identity = 50/200 (25.00%), Postives = 85/200 (42.50%), Query Frame = 2 Query: 986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQIS 1585 G+ + + +Y+ Y++ + L+ +LDG P P C+ + ++ MWR FDV LH +L +V+ P+ + + FAFV +HG D W +L+ E+ ++ + V L + SP RL A A S + F GI + + + W V + G + YSH I+ Sbjct: 293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPW-VTLSVLGFLYCYSHVDIA 491
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Match: sp|Q9VZU2|HHAT_DROME (Protein-cysteine N-palmitoyltransferase Rasp OS=Drosophila melanogaster OX=7227 GN=rasp PE=2 SV=1) HSP 1 Score: 52.7582 bits (125), Expect = 6.121e-6 Identity = 83/413 (20.10%), Postives = 168/413 (40.68%), Query Frame = 2 Query: 152 DVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNN--KKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPF-TFYIFISKLLRSYTSPKMFMFGNL---LITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYM------PDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKL--VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILK 1336 D +++ E Y +++ ++ G+Y+IY L ++ K+ + QF + + S +N+ L E F+ PF ++ + +R + P++ G + + N +SS V + ++ I L K L+W++ + + M D Y +Y L + + + R S L+ A + D+ +++ Y YFP + ++ + F + +++W ++ +R A + + +HY Y+ ++ D + ++ + F G +++ Y++ Y DG P CI I YS MW+ FD L+ +L +++ + ++ A FAFV +HG L W L+ AE + K Sbjct: 6 DRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDEL--ENFGDFIVSFWPFYLLHVAVQGFIR-WKRPRLQCLGFIGVCALALSVNLDWSSMVLL---VTLIASYYIVSLLSLKFLVWLLSAGWILCINVMQKNVWWTDRVGYTEYVLVIVTMSWSVL---RGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIWWLVMQCALHY--FYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFK 405
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V0RNH6 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella nelsoni OX=6336 GN=HHAT PE=3 SV=1) HSP 1 Score: 102.064 bits (253), Expect = 3.361e-19 Identity = 107/451 (23.73%), Postives = 205/451 (45.45%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTI---SEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 T E++K++ + P + E AFY + + Y++++L+N + Q + + K L K N Y W + ++VR A+P+ F + KLL + T K FM ++ W F +Y A + V I T + A R K +W I LY +++ + D++ + + S ++ + +S L + ++ ++++Y Y P + +++ K F ++ + E + L +RI + +++H H+Y ++ + + + + C + G +++ Y++ + +LD GP CI + LYS +WR+FD L+ + K+++F PIA+ FRI R A + F+FV+ +HG R + W+ L++ + + ENI K I+ F V EK S RR++ Sbjct: 16 TSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQSVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSREMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPSGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 451
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V1CGW5 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella britovi OX=45882 GN=HHAT PE=3 SV=1) HSP 1 Score: 99.3673 bits (246), Expect = 3.004e-18 Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 + E++K++ + P + E AFY + + Y++++L+N + Q + + K L K N Y W + ++VR A+P+ F + KLL + T K FM ++ W F +Y A + V I T + A R K +W I LY +++ + D++ + + S ++ + +S L I P ++ ++++Y Y P + +++ K F ++ + + + L +RI + +++H H+Y ++ + + + + C + G +++ Y++ + +LD GP CI + LYS +WR+FD L+ + K+++F PIA+ FRI R A + F+FV+ +HG R + W+ L++ + + ENI K I+ F V EK S RR++ Sbjct: 50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCQHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V0UPL8 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella sp. T9 OX=181606 GN=T09_6398 PE=3 SV=1) HSP 1 Score: 99.3673 bits (246), Expect = 3.405e-18 Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 + E++K++ + P + E AFY + + Y++++L+N + Q + + K L K N Y W + ++VR A+P+ F + KLL + T K FM ++ W F +Y A + V I T + A R K +W I LY +++ + D++ + + S ++ + +S L I P ++ ++++Y Y P + +++ K F ++ + + + L +RI + +++H H+Y ++ + + + + C + G +++ Y++ + +LD GP CI + LYS +WR+FD L+ + K+++F PIA+ FRI R A + F+FV+ +HG R + W+ L++ + + ENI K I+ F V EK S RR++ Sbjct: 50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A1Y3ES49 (MBOAT family protein OS=Trichinella nativa OX=6335 GN=D917_06718 PE=3 SV=1) HSP 1 Score: 99.3673 bits (246), Expect = 3.405e-18 Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 + E++K++ + P + E AFY + + Y++++L+N + Q + + K L K N Y W + ++VR A+P+ F + KLL + T K FM ++ W F +Y A + V I T + A R K +W I LY +++ + D++ + + S ++ + +S L I P ++ ++++Y Y P + +++ K F ++ + + + L +RI + +++H H+Y ++ + + + + C + G +++ Y++ + +LD GP CI + LYS +WR+FD L+ + K+++F PIA+ FRI R A + F+FV+ +HG R + W+ L++ + + ENI K I+ F V EK S RR++ Sbjct: 50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V1EAM2 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella pseudospiralis OX=6337 GN=HHAT PE=3 SV=1) HSP 1 Score: 98.2117 bits (243), Expect = 5.973e-18 Identity = 105/447 (23.49%), Postives = 204/447 (45.64%), Query Frame = 2 Query: 128 EREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQF---LKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLF--RHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISE---APKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIY-KPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411 E++K++ + P + E AFY + + Y++++L+N + Q L N + L ++N Y W + ++VR A+P+ F + KLLR+ T K FM ++ W F +Y A + V TF + R K +W I LY +++ + D++ + + S ++ + +S L + + + ++++Y Y P + +++ K F ++ + + L +RI + +++H H+Y ++ + + + + C + G +++ Y++ + +LD GP CI + LYS +WR+FD L+ + K+++F PIA+ FRI R A + F+FV+ +HG RR + W+ L++ + + EN K I+ F V EK S RR++ Sbjct: 19 EQKKRQSFKYPSLPNGETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAPLTNSHLWLIGDKLKDTSN-YEWQHWI-VWVREALPWYFVHSLLFNCTEKLLRT-TVWKRFM----IVYWIFASWYLFATHIVLTVFTAATFMYCAAYWLRSKLAVWTITLGILYVAVEGIVDFAADEDAF---KSISFIGYKMLQCLSFCLDLIDNRAVCDHFFDGFFKLAWYMLYLPYQLSL-IVIYKRFQPDMECRNSRQMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNIELLTSIPLDTLCCIGALLGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRRSCMVWVGLNVVEILIENFGKVIYSFQSVQKLREKLISDQCFRRIL 451
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Sea Lamprey
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1]) HSP 1 Score: 60.8474 bits (146), Expect = 3.409e-10 Identity = 33/107 (30.84%), Postives = 52/107 (48.60%), Query Frame = 2 Query: 1013 YYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENIL 1333 +Y+ Y++ + L LDG P P C+ +S MWRNFDV LH WL +V+ P+ + + + A F +V +HG + L+W +L+ E L Sbjct: 274 FYVKYLVLFGVPSLAMHLDGVQPPPLPRCVSITHGFSDMWRNFDVGLHRWLLRYVYVPLGGSQGGALRQAVSCGAVFLYVFFWHGAQAYLLFWATLNWLGVTVETGL 380
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Match: EDO33140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST26]) HSP 1 Score: 64.3142 bits (155), Expect = 6.014e-11 Identity = 60/223 (26.91%), Postives = 104/223 (46.64%), Query Frame = 2 Query: 665 LAVLFTRAISVGLTISEAPKYDMKL----VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWL---FSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVV--ACGVQMFYGIHYYMV-YIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIA---KLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWI 1294 L + R G+T + K D L +L++ Y +Y P LM K+F ++P + E L + ++R + + +HY + +V D K + V G+ M+ ++ ++V Y++ Y+ S L + D P C+ + L+ MWR FD L++W+K +++ P+ K P +IT F A F FV +HG R D L+W+ Sbjct: 224 LECCWHRQDGAGVT---SDKTDKPLPSFTLLDLLLYNFYLPLFANGPLMTYKDFYTQFHQPVQLLTKPELLTILWDAIRTLWWYIFLEVYLHYMY-SAALVRKDPVFKGLSVWTITGI-MYSQLNIFLVKYVVLYRLSGLFARFDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSQKGIPRQITGSFLA---FTFVWAWHGSRVDILWWV 438
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Match: EDO38150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDP8]) HSP 1 Score: 61.2326 bits (147), Expect = 5.973e-10 Identity = 54/222 (24.32%), Postives = 94/222 (42.34%), Query Frame = 2 Query: 665 LAVLFTRAISVGLTISEAPKYDMKL-VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWL---FSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMV------YIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIA---KLGPFRITRYFAAIACFAFVVNFHGLRRDNLYW 1291 L + R G+T + K +L++ Y +Y P +M K+F ++P + E L + ++R + + +HY + + + + GI Y + Y++ Y S L +LD P C+ + L+ MWR FD L++W+K +++ P+ K P +IT F A F FV +HG + DNL+W Sbjct: 224 LECCWHRQDGAGVTRDKTDKPSPSFTLLDLLLYNFYLPLFANGPVMTYKDFHTQFHQPVQLLTKPELLTILWDAIRTLWWYIFLEVYLHYMYSAALV-----REAPVFKGLSAWTITGIMYSQLNIFLTKYVVLYLLSGLFARLDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSRKGIPRQITGSFLA---FTFVWAWHGGQVDNLWW 437
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552]) HSP 1 Score: 55.0694 bits (131), Expect = 1.169e-7 Identity = 95/439 (21.64%), Postives = 181/439 (41.23%), Query Frame = 2 Query: 155 VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGF-IQKGSF-GLYKSNNEYLWDELMELFVRGAVPFTF--YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQ----MEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYL----AVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRI-AAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC-------GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 V P+ + E Y WV +Y ++L K + L F ++KG G + ++++ W + + R ++ T + +S+L Y PK F L IT Y S + + V + +TF +A L + ++ W+ L + ++ P K +Y+ + L AV R IS L + + + + Y +Y P +M K F + + + + FS + + + I +W + C I+ + H Q+ + G+ + +Y+ Y++ + ++ LD + P C+ + ++ MWR+FD L+ WL +++ P+ ++ GP + + FAF+ +HG YW ++ +AEN L +F V +E+ FS RR Sbjct: 5 VSPLPQTEILVY---WVLSFGSHLYSFFQLHKFSKEHEAGLSREFQLEKGLLQGFKRDSSDFEWSFWSD-WGRKSLLLTLIGHCVVSRL-SGYFYPK---FKVLAITLYGLLAAVSVLGVKGVSVLLVHLSVTFLVAQL-QKPAMSWMCNLLLIATLYIQPIQEIQKSWYMTEEEYYLLLFSVAVCSLRFISFSLEQCWSSCNALVQLFWLLAYTFYHPFFYNGPIMTYKAFTEQMQRSTEENNRTTFAFSHLLLRSGRILLWWCLAE-CLIHF-MYMHSIQSNETYIEILPPWALGGLALALVQFFYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLH--KLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRR 430
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552]) HSP 1 Score: 55.0694 bits (131), Expect = 1.407e-7 Identity = 95/439 (21.64%), Postives = 181/439 (41.23%), Query Frame = 2 Query: 155 VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGF-IQKGSF-GLYKSNNEYLWDELMELFVRGAVPFTF--YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQ----MEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYL----AVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRI-AAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC-------GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405 V P+ + E Y WV +Y ++L K + L F ++KG G + ++++ W + + R ++ T + +S+L Y PK F L IT Y S + + V + +TF +A L + ++ W+ L + ++ P K +Y+ + L AV R IS L + + + + Y +Y P +M K F + + + + FS + + + I +W + C I+ + H Q+ + G+ + +Y+ Y++ + ++ LD + P C+ + ++ MWR+FD L+ WL +++ P+ ++ GP + + FAF+ +HG YW ++ +AEN L +F V +E+ FS RR Sbjct: 5 VSPLPQTEILVY---WVLSFGSHLYSFFQLHKFSKEHEAGLSREFQLEKGLLQGFKRDSSDFEWSFWSD-WGRKSLLLTLIGHCVVSRL-SGYFYPK---FKVLAITLYGLLAAVSVLGVKGVSVLLVHLSVTFLVAQL-QKPAMSWMCNLLLIATLYIQPIQEIQKSWYMTEEEYYLLLFSVAVCSLRFISFSLEQCWSSCNALVQLFWLLAYTFYHPFFYNGPIMTYKAFTEQMQRSTEENNRTTFAFSHLLLRSGRILLWWCLAE-CLIHF-MYMHSIQSNETYIEILPPWALGGLALALVQFFYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLH--KLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRR 430
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001671.1 (SMESG000001671.1) HSP 1 Score: 927.932 bits (2397), Expect = 0.000e+0 Identity = 474/504 (94.05%), Postives = 482/504 (95.63%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630 TKCEREKQKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFL+NGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLI+WYFNYYYSSAKFFQMEVLIFLTFAIAGLFR KSLIWIIGCLSLYSMKYMPDYSFYK YLFHNS+PYLAVLFTRAISVGL ISEAP+YDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTH WQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMW HVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQY AENILKYIFLFTWVGPYLEKTFSPIWLRRLIAAAVAASF SSVWAFA FQYGI IANALYFSSLNKNLSW+VERFITGSAFIYSHAQISLTVNEYLRKRKLKTA Sbjct: 25 TKCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLENGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLISWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRQKSLIWIIGCLSLYSMKYMPDYSFYKDDYLFHNSYPYLAVLFTRAISVGLAISEAPRYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHYWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMW------------SHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTWVGPYLEKTFSPIWLRRLIAAAVAASFLSSVWAFAVFQYGISIANALYFSSLNKNLSWIVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 516
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1) HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0 Identity = 333/339 (98.23%), Postives = 336/339 (99.12%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 1135 TKCERE QKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMP YSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTI THDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR Sbjct: 25 TKCERENQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 363
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1) HSP 1 Score: 532.332 bits (1370), Expect = 0.000e+0 Identity = 259/262 (98.85%), Postives = 260/262 (99.24%), Query Frame = 2 Query: 350 MELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 1135 MELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMP YSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTI THDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR Sbjct: 1 MELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 262
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001542.1 (SMESG000001542.1) HSP 1 Score: 460.685 bits (1184), Expect = 1.140e-157 Identity = 233/503 (46.32%), Postives = 342/503 (67.99%), Query Frame = 2 Query: 122 KCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630 K ER + KDY++P ISK+E L+IW +L+G Y+ YKL KKT + F K I FGLY S + WDEL++L P Y+ +SKL R SP + M N ++ FNYYYSS KF ME++IFL A+ GLF+ K+L+WI G LY ++Y+ Y F+ ++F +++PY +L TR+IS+GLTI+++ K D K LEM ++++YFPAI+GCR+M +K+F+ IYKP +I +WK W ++ Y +W+ + + H+ L + TH+ + H V G Q+F G+H+YMVY++FY+ ++L+TQLDGFLT GPECI HI LYSRMW+NFD LH+WLK+++FRP+ KLG F +T++FA A F FV FHG++ +N+ WI++++FQY +EN+LK+++L T G +E+ FSPI +RR+IA + A SF S++AFA+F +G+ +AN++YFS +L+ L R F Y+H+Q+SLTVNEYLRKRK K + Sbjct: 9 KDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVIMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSDSKSFLEMLYFYFYFPAIVGCRMMNVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQINNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKSKDS 511
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001654.1 (SMESG000001654.1) HSP 1 Score: 262.692 bits (670), Expect = 1.250e-83 Identity = 150/159 (94.34%), Postives = 153/159 (96.23%), Query Frame = 2 Query: 1154 HLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630 +L + HVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQY AENILKYIFLFT VGPYLEKTFSPIWLRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNK+ SWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA Sbjct: 135 NLLITCHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTCVGPYLEKTFSPIWLRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNKSFSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 293 HSP 2 Score: 231.106 bits (588), Expect = 1.736e-71 Identity = 111/115 (96.52%), Postives = 114/115 (99.13%), Query Frame = 2 Query: 119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLIT 463 TKCEREKQKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYI ISKLLRSYTSPKMFMFGNLLIT Sbjct: 25 TKCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIIISKLLRSYTSPKMFMFGNLLIT 139 The following BLAST results are available for this feature:
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 2
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032865 ID=SMED30032865|Name=Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein)|organism=Schmidtea mediterranea sexual|type=transcript|length=1672bpback to top protein sequence of SMED30032865-orf-1 >SMED30032865-orf-1 ID=SMED30032865-orf-1|Name=SMED30032865-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=529bp MSKITNEESIEKENKSEKESVPEETKCEREKQKDYDVPPISKLEFAFYLLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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