Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein)

Overview
NameProtein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein)
Smed IDSMED30032865
Length (bp)1672
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) (SMED30032865) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) (SMED30032865) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) (SMED30032865) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) (SMED30032865) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032865

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30032865h1SMcG0018020 dd_Smed_v4_17532_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30032865h1SMcG0018020 dd_Smed_v4_17532_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30032865h1SMcG0018022 Contig45756newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032865h1SMcG0018022 Contig45756uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032865h1SMcG0018020 Contig45756newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032865h1SMcG0018020 Contig45756uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 56.9954 bits (136), Expect = 5.104e-8
Identity = 39/148 (26.35%), Postives = 68/148 (45.95%), Query Frame = 2
Query:  974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
             V+C    G+ +   + +Y+ Y++ +    L+ +LDG      P C+  +  ++ MWR FDV LH +L  +V+ P+       +   F+    FAFV  +HG       W +L+      EN ++ +     +   L + FSP   RR
Sbjct:  214 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 361          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 56.9954 bits (136), Expect = 5.104e-8
Identity = 39/148 (26.35%), Postives = 68/148 (45.95%), Query Frame = 2
Query:  974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
             V+C    G+ +   + +Y+ Y++ +    L+ +LDG      P C+  +  ++ MWR FDV LH +L  +V+ P+       +   F+    FAFV  +HG       W +L+      EN ++ +     +   L + FSP   RR
Sbjct:  214 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 361          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 56.9954 bits (136), Expect = 6.787e-8
Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
            G+ +   + +Y+ Y++ +    L+ +LDG      P C+  +  ++ MWR FDV LH +L  +V+ P+       +   F+    FAFV  +HG       W +L+      EN ++ +     +   L + FSP   RR
Sbjct:  288 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 427          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 56.9954 bits (136), Expect = 6.787e-8
Identity = 37/140 (26.43%), Postives = 65/140 (46.43%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
            G+ +   + +Y+ Y++ +    L+ +LDG      P C+  +  ++ MWR FDV LH +L  +V+ P+       +   F+    FAFV  +HG       W +L+      EN ++ +     +   L + FSP   RR
Sbjct:  288 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 427          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 56.225 bits (134), Expect = 7.365e-8
Identity = 41/149 (27.52%), Postives = 71/149 (47.65%), Query Frame = 2
Query:  974 VVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLY-WISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
             V+C    G+ +   + +Y+ Y++ +    L+ +LDG      P C+  +  ++ MWR FDV LH +L  +V+ P+       +   F+    FAFV  +HG   D L+ W +L+      EN ++ +     +   L + FSP   RR
Sbjct:  142 TVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHG-GYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRR 289          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Match: hhat-1 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:G5EFT7])

HSP 1 Score: 77.7962 bits (190), Expect = 6.068e-15
Identity = 52/192 (27.08%), Postives = 90/192 (46.88%), Query Frame = 2
Query:  845 EDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
             +W +  +S VRIA + ++    +H+ +    +    +     K   VA G+ M  GI +++ Y + +    L  +LD     PGP C++ + LYS++WR FD  L+ + K ++F PI         + F     + FV+ +HG    N+ WI L+I     E   K I+    V  + E   S +  RR++
Sbjct:  254 RNWLDCAWSGVRIAFWWWLMEASLHFLYHEAILKNAPYLYSLPKDQFVALGMAM--GIFFHLKYAVIFGLPTLFAKLDNMDPLPGPICLIRVTLYSKVWREFDRGLYQFFKTYIFIPICAPTFSLPRKIFGVFISYGFVLLWHGFYHHNIVWIGLNILALFIEMGSKAIYTIESVRKWREANLSDVAFRRIL 443          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Match: hhat-2 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:O18241])

HSP 1 Score: 69.3218 bits (168), Expect = 3.343e-12
Identity = 41/113 (36.28%), Postives = 62/113 (54.87%), Query Frame = 2
Query: 1004 GIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRP-IAKLGPF--RITRYFAAI-ACFAFVVNFHGLRRDNLYWISLSIFQYMAENI 1330
            G  +++ Y++ +        LDGF   P P CI  ++LYSRMWR FD  L+ +LK  V+ P + K  P    I R   A+ A F  V+ +HG RR  ++W++LS  + + E I
Sbjct:  303 GQLFHVKYVVIFGVPAFFAALDGFRPPPPPICISRVSLYSRMWRFFDNGLYQFLKYQVYIPAMRKPLPLFWSILRSLGALCAVFGVVLAWHGTRRHFIFWVTLSATELIVERI 415          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Fly
Match: rasp (gene:FBgn0024194 transcript:FBtr0073029)

HSP 1 Score: 52.7582 bits (125), Expect = 6.106e-7
Identity = 83/413 (20.10%), Postives = 168/413 (40.68%), Query Frame = 2
Query:  152 DVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNN--KKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPF-TFYIFISKLLRSYTSPKMFMFGNL---LITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYM------PDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKL--VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILK 1336
            D   +++ E   Y  +++  ++ G+Y+IY L ++  K+ + QF +   +   S      +N+ L  E    F+    PF   ++ +   +R +  P++   G +    +    N  +SS       V +  ++ I  L   K L+W++    +  +  M       D   Y +Y L   +  +  +   R  S  L+   A + D+    +++   Y  YFP +    ++  + F     +   +++W  ++   +R A +  +    +HY   Y+  ++ D +   ++ +         F G  +++ Y++ Y         DG      P CI  I  YS MW+ FD  L+ +L  +++  +         ++ A    FAFV  +HG     L W  L+     AE + K
Sbjct:    6 DRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDEL--ENFGDFIVSFWPFYLLHVAVQGFIR-WKRPRLQCLGFIGVCALALSVNLDWSSMVLL---VTLIASYYIVSLLSLKFLVWLLSAGWILCINVMQKNVWWTDRVGYTEYVLVIVTMSWSVL---RGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIWWLVMQCALHY--FYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFK 405          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Zebrafish
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1])

HSP 1 Score: 59.6918 bits (143), Expect = 4.866e-9
Identity = 53/213 (24.88%), Postives = 101/213 (47.42%), Query Frame = 2
Query:  743 LEMSFYFWYFPAIIGCRLMVIKEFINNIYKP-CVIEDWKEWLFSSV-RIAAYIFIWNIVMHYCHI--------YLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIF 1345
            L+++ + +Y P      +M  K+F   I +P C +      +FS + R+  +  +   ++H+ ++        YL ++   W    + +A  VQ FY     + Y++ + +  L+ +LDG      P C+  +  ++ MWR+FDV L+ WL  +++ P+  ++ G FR  +  +    F FV  +HG     LYW  L+    + EN    +F
Sbjct:  224 LKLTAFCFYHPLFYNGPIMTYKDFSEQIERPLCKVSALH--VFSGILRLCVWWCLAEFMIHFMYMHAIQSNETYLEMLP-PWAMGGLALAL-VQFFY-----VKYLVLFGAVSLLVRLDGLEPPTLPRCVSIMYSFTGMWRHFDVGLYKWLIRYIYVPLGGSRHGAFR--KLLSTALAFGFVCFWHGCHDYLLYWALLNWVGVLVENAFALLF 425          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Xenopus
Match: HHAT (hedgehog acyltransferase [Source:NCBI gene;Acc:100490766])

HSP 1 Score: 58.151 bits (139), Expect = 2.002e-8
Identity = 36/141 (25.53%), Postives = 68/141 (48.23%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408
            G+ +   + +Y+ Y++ Y    LI +LDG      P C+  +  ++ +WR+FDV LH +L  +++ P+            ++   F FV  +HG      YW +L+    +AE+  K +     V   +++T SP   R++
Sbjct:  189 GLALAQVLFFYVKYLVLYGLPALIVRLDGLDPPALPRCVSTMYSFTGIWRSFDVGLHRFLVRYIYIPLGGSQRGLHGMLLSSALTFIFVCCWHGAHEYLWYWAALNWIGLVAEHAGKKLLDIPVVQHAVDRTLSPKMHRQI 329          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 59.6918 bits (143), Expect = 5.745e-9
Identity = 50/200 (25.00%), Postives = 85/200 (42.50%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQIS 1585
            G+ +   + +Y+ Y++ +    L+ +LDG    P P C+  +  ++ MWR FDV LH +L  +V+ P+       +    +    FAFV  +HG   D   W +L+      E+ ++ +     V   L +  SP    RL A   A S    +     F  GI +    +     +   W V   + G  + YSH  I+
Sbjct:  293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPW-VTLSVLGFLYCYSHVDIA 491          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 59.3066 bits (142), Expect = 6.817e-9
Identity = 37/141 (26.24%), Postives = 65/141 (46.10%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408
            G+ +   + +Y+ Y++ +    L+ +LDG    P P C+  +  ++ MWR FDV LH +L  +V+ P+       +    +    FAFV  +HG   D   W +L+      E+ ++ +     V   L +  SP    RL
Sbjct:  293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRL 433          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 59.3066 bits (142), Expect = 6.991e-9
Identity = 37/141 (26.24%), Postives = 65/141 (46.10%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRL 1408
            G+ +   + +Y+ Y++ +    L+ +LDG    P P C+  +  ++ MWR FDV LH +L  +V+ P+       +    +    FAFV  +HG   D   W +L+      E+ ++ +     V   L +  SP    RL
Sbjct:  293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRL 433          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Match: sp|Q8BMT9|HHAT_MOUSE (Protein-cysteine N-palmitoyltransferase HHAT OS=Mus musculus OX=10090 GN=Hhat PE=2 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 4.018e-8
Identity = 50/200 (25.00%), Postives = 85/200 (42.50%), Query Frame = 2
Query:  986 GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQIS 1585
            G+ +   + +Y+ Y++ +    L+ +LDG    P P C+  +  ++ MWR FDV LH +L  +V+ P+       +    +    FAFV  +HG   D   W +L+      E+ ++ +     V   L +  SP    RL A   A S    +     F  GI +    +     +   W V   + G  + YSH  I+
Sbjct:  293 GLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPW-VTLSVLGFLYCYSHVDIA 491          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Match: sp|Q9VZU2|HHAT_DROME (Protein-cysteine N-palmitoyltransferase Rasp OS=Drosophila melanogaster OX=7227 GN=rasp PE=2 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 6.121e-6
Identity = 83/413 (20.10%), Postives = 168/413 (40.68%), Query Frame = 2
Query:  152 DVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNN--KKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPF-TFYIFISKLLRSYTSPKMFMFGNL---LITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYM------PDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKL--VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC----GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILK 1336
            D   +++ E   Y  +++  ++ G+Y+IY L ++  K+ + QF +   +   S      +N+ L  E    F+    PF   ++ +   +R +  P++   G +    +    N  +SS       V +  ++ I  L   K L+W++    +  +  M       D   Y +Y L   +  +  +   R  S  L+   A + D+    +++   Y  YFP +    ++  + F     +   +++W  ++   +R A +  +    +HY   Y+  ++ D +   ++ +         F G  +++ Y++ Y         DG      P CI  I  YS MW+ FD  L+ +L  +++  +         ++ A    FAFV  +HG     L W  L+     AE + K
Sbjct:    6 DRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDEL--ENFGDFIVSFWPFYLLHVAVQGFIR-WKRPRLQCLGFIGVCALALSVNLDWSSMVLL---VTLIASYYIVSLLSLKFLVWLLSAGWILCINVMQKNVWWTDRVGYTEYVLVIVTMSWSVL---RGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIWWLVMQCALHY--FYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFK 405          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V0RNH6 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella nelsoni OX=6336 GN=HHAT PE=3 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 3.361e-19
Identity = 107/451 (23.73%), Postives = 205/451 (45.45%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTI---SEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
            T  E++K++ +  P +   E AFY  +    +    Y++++L+N  + Q   +    + K    L     K  N Y W   + ++VR A+P+ F     +    KLL + T  K FM    ++ W F  +Y  A    + V I  T  +  A   R K  +W I    LY +++ + D++  +  +    S  ++     + +S  L +       ++      ++++Y  Y P  +   +++ K F  ++ +    E +    L   +RI  +     +++H  H+Y   ++ + +   +  +   C +    G  +++ Y++ +       +LD      GP CI  + LYS +WR+FD  L+ + K+++F PIA+   FRI R  A  +  F+FV+ +HG R   + W+ L++ + + ENI K I+ F  V    EK  S    RR++
Sbjct:   16 TSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQSVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSREMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPSGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 451          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V1CGW5 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella britovi OX=45882 GN=HHAT PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.004e-18
Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
            +  E++K++ +  P +   E AFY  +    +    Y++++L+N  + Q   +    + K    L     K  N Y W   + ++VR A+P+ F     +    KLL + T  K FM    ++ W F  +Y  A    + V I  T  +  A   R K  +W I    LY +++ + D++  +  +    S  ++     + +S  L  I   P  ++      ++++Y  Y P  +   +++ K F  ++ +    + +    L   +RI  +     +++H  H+Y   ++ + +   +  +   C +    G  +++ Y++ +       +LD      GP CI  + LYS +WR+FD  L+ + K+++F PIA+   FRI R  A  +  F+FV+ +HG R   + W+ L++ + + ENI K I+ F  V    EK  S    RR++
Sbjct:   50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCQHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V0UPL8 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella sp. T9 OX=181606 GN=T09_6398 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.405e-18
Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
            +  E++K++ +  P +   E AFY  +    +    Y++++L+N  + Q   +    + K    L     K  N Y W   + ++VR A+P+ F     +    KLL + T  K FM    ++ W F  +Y  A    + V I  T  +  A   R K  +W I    LY +++ + D++  +  +    S  ++     + +S  L  I   P  ++      ++++Y  Y P  +   +++ K F  ++ +    + +    L   +RI  +     +++H  H+Y   ++ + +   +  +   C +    G  +++ Y++ +       +LD      GP CI  + LYS +WR+FD  L+ + K+++F PIA+   FRI R  A  +  F+FV+ +HG R   + W+ L++ + + ENI K I+ F  V    EK  S    RR++
Sbjct:   50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A1Y3ES49 (MBOAT family protein OS=Trichinella nativa OX=6335 GN=D917_06718 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.405e-18
Identity = 107/451 (23.73%), Postives = 206/451 (45.68%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGL----YKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLT--FAIAGLFRHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLT-ISEAP--KYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIE-DWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
            +  E++K++ +  P +   E AFY  +    +    Y++++L+N  + Q   +    + K    L     K  N Y W   + ++VR A+P+ F     +    KLL + T  K FM    ++ W F  +Y  A    + V I  T  +  A   R K  +W I    LY +++ + D++  +  +    S  ++     + +S  L  I   P  ++      ++++Y  Y P  +   +++ K F  ++ +    + +    L   +RI  +     +++H  H+Y   ++ + +   +  +   C +    G  +++ Y++ +       +LD      GP CI  + LYS +WR+FD  L+ + K+++F PIA+   FRI R  A  +  F+FV+ +HG R   + W+ L++ + + ENI K I+ F  V    EK  S    RR++
Sbjct:   50 SSVEQKKRQRFKYPSLPSSETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAP--LTKSHLWLIGDKLKDTNNYEWQHWI-VWVREALPWYFLHSLLFNCTEKLLGT-TLWKRFM----IVYWIFASWYLFATHIVLTVFIAATVMYGAAYWLRSKLAVWTITLGILYVAVEGIVDFAADQDAF---KSISFIGYKMLQCLSFCLDLIDNQPVCEHFFDGFFKLAWYILYLPYQLSL-IVIYKRFQPDMERRNSRDMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNVELLTSMPLDTLCCIGALIGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRHSCMVWVGLNVVEILIENIGKVIYSFQSVQKLREKLISDQCFRRIL 485          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Match: A0A0V1EAM2 (Protein-cysteine N-palmitoyltransferase HHAT OS=Trichinella pseudospiralis OX=6337 GN=HHAT PE=3 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 5.973e-18
Identity = 105/447 (23.49%), Postives = 204/447 (45.64%), Query Frame = 2
Query:  128 EREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQF---LKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTF-----YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLF--RHKSLIWIIGCLSLY-SMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISE---APKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIY-KPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQ---NKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAA-IACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLI 1411
            E++K++ +  P +   E AFY  +    +    Y++++L+N  + Q      L N  +      L  ++N Y W   + ++VR A+P+ F     +    KLLR+ T  K FM    ++ W F  +Y  A    + V    TF     +  R K  +W I    LY +++ + D++  +  +    S  ++     + +S  L + +      +      ++++Y  Y P  +   +++ K F  ++  +     +    L   +RI  +     +++H  H+Y   ++ + +   +  +   C +    G  +++ Y++ +       +LD      GP CI  + LYS +WR+FD  L+ + K+++F PIA+   FRI R  A  +  F+FV+ +HG RR  + W+ L++ + + EN  K I+ F  V    EK  S    RR++
Sbjct:   19 EQKKRQSFKYPSLPNGETAFYFAVISCTIFYTWYKVFQLSNEPQVQNNTVAPLTNSHLWLIGDKLKDTSN-YEWQHWI-VWVREALPWYFVHSLLFNCTEKLLRT-TVWKRFM----IVYWIFASWYLFATHIVLTVFTAATFMYCAAYWLRSKLAVWTITLGILYVAVEGIVDFAADEDAF---KSISFIGYKMLQCLSFCLDLIDNRAVCDHFFDGFFKLAWYMLYLPYQLSL-IVIYKRFQPDMECRNSRQMNLSRTLLFGIRILFWYCFTELLLH--HLYFEAISMNIELLTSIPLDTLCCIGALLGQFFHLKYVVIFGFPAFFAKLDKMTPPNGPICISRVTLYSNIWRHFDRGLYEFFKEYIFLPIAR-PSFRIERKLAGLLLSFSFVLVWHGFRRSCMVWVGLNVVEILIENFGKVIYSFQSVQKLREKLISDQCFRRIL 451          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Sea Lamprey
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1])

HSP 1 Score: 60.8474 bits (146), Expect = 3.409e-10
Identity = 33/107 (30.84%), Postives = 52/107 (48.60%), Query Frame = 2
Query: 1013 YYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENIL 1333
            +Y+ Y++ +    L   LDG    P P C+     +S MWRNFDV LH WL  +V+ P+       + +  +  A F +V  +HG +   L+W +L+      E  L
Sbjct:  274 FYVKYLVLFGVPSLAMHLDGVQPPPLPRCVSITHGFSDMWRNFDVGLHRWLLRYVYVPLGGSQGGALRQAVSCGAVFLYVFFWHGAQAYLLFWATLNWLGVTVETGL 380          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Match: EDO33140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST26])

HSP 1 Score: 64.3142 bits (155), Expect = 6.014e-11
Identity = 60/223 (26.91%), Postives = 104/223 (46.64%), Query Frame = 2
Query:  665 LAVLFTRAISVGLTISEAPKYDMKL----VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWL---FSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVV--ACGVQMFYGIHYYMV-YIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIA---KLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWI 1294
            L   + R    G+T   + K D  L    +L++  Y +Y P      LM  K+F    ++P  +    E L   + ++R   +     + +HY +    +V  D   K + V    G+ M+  ++ ++V Y++ Y+ S L  + D       P C+  + L+  MWR FD  L++W+K +++ P+    K  P +IT  F A   F FV  +HG R D L+W+
Sbjct:  224 LECCWHRQDGAGVT---SDKTDKPLPSFTLLDLLLYNFYLPLFANGPLMTYKDFYTQFHQPVQLLTKPELLTILWDAIRTLWWYIFLEVYLHYMY-SAALVRKDPVFKGLSVWTITGI-MYSQLNIFLVKYVVLYRLSGLFARFDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSQKGIPRQITGSFLA---FTFVWAWHGSRVDILWWV 438          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Match: EDO38150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDP8])

HSP 1 Score: 61.2326 bits (147), Expect = 5.973e-10
Identity = 54/222 (24.32%), Postives = 94/222 (42.34%), Query Frame = 2
Query:  665 LAVLFTRAISVGLTISEAPKYDMKL-VLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWL---FSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMV------YIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIA---KLGPFRITRYFAAIACFAFVVNFHGLRRDNLYW 1291
            L   + R    G+T  +  K      +L++  Y +Y P      +M  K+F    ++P  +    E L   + ++R   +     + +HY +    +     +   +          GI Y  +      Y++ Y  S L  +LD       P C+  + L+  MWR FD  L++W+K +++ P+    K  P +IT  F A   F FV  +HG + DNL+W
Sbjct:  224 LECCWHRQDGAGVTRDKTDKPSPSFTLLDLLLYNFYLPLFANGPVMTYKDFHTQFHQPVQLLTKPELLTILWDAIRTLWWYIFLEVYLHYMYSAALV-----REAPVFKGLSAWTITGIMYSQLNIFLTKYVVLYLLSGLFARLDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSRKGIPRQITGSFLA---FTFVWAWHGGQVDNLWW 437          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552])

HSP 1 Score: 55.0694 bits (131), Expect = 1.169e-7
Identity = 95/439 (21.64%), Postives = 181/439 (41.23%), Query Frame = 2
Query:  155 VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGF-IQKGSF-GLYKSNNEYLWDELMELFVRGAVPFTF--YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQ----MEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYL----AVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRI-AAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC-------GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
            V P+ + E   Y   WV      +Y  ++L    K  +  L   F ++KG   G  + ++++ W    + + R ++  T   +  +S+L   Y  PK   F  L IT Y      S    +    + V + +TF +A L +  ++ W+   L + ++   P     K +Y+    +  L    AV   R IS  L    +    +  +  +  Y +Y P      +M  K F   + +     +   + FS + + +  I +W  +   C I+  +  H  Q+    +         G+ +     +Y+ Y++ +    ++  LD  +    P C+  +  ++ MWR+FD  L+ WL  +++ P+  ++ GP    +  +    FAF+  +HG      YW  ++    +AEN L  +F    V   +E+ FS    RR
Sbjct:    5 VSPLPQTEILVY---WVLSFGSHLYSFFQLHKFSKEHEAGLSREFQLEKGLLQGFKRDSSDFEWSFWSD-WGRKSLLLTLIGHCVVSRL-SGYFYPK---FKVLAITLYGLLAAVSVLGVKGVSVLLVHLSVTFLVAQL-QKPAMSWMCNLLLIATLYIQPIQEIQKSWYMTEEEYYLLLFSVAVCSLRFISFSLEQCWSSCNALVQLFWLLAYTFYHPFFYNGPIMTYKAFTEQMQRSTEENNRTTFAFSHLLLRSGRILLWWCLAE-CLIHF-MYMHSIQSNETYIEILPPWALGGLALALVQFFYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLH--KLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRR 430          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552])

HSP 1 Score: 55.0694 bits (131), Expect = 1.407e-7
Identity = 95/439 (21.64%), Postives = 181/439 (41.23%), Query Frame = 2
Query:  155 VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGF-IQKGSF-GLYKSNNEYLWDELMELFVRGAVPFTF--YIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQ----MEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYL----AVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRI-AAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVAC-------GVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPI--AKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRR 1405
            V P+ + E   Y   WV      +Y  ++L    K  +  L   F ++KG   G  + ++++ W    + + R ++  T   +  +S+L   Y  PK   F  L IT Y      S    +    + V + +TF +A L +  ++ W+   L + ++   P     K +Y+    +  L    AV   R IS  L    +    +  +  +  Y +Y P      +M  K F   + +     +   + FS + + +  I +W  +   C I+  +  H  Q+    +         G+ +     +Y+ Y++ +    ++  LD  +    P C+  +  ++ MWR+FD  L+ WL  +++ P+  ++ GP    +  +    FAF+  +HG      YW  ++    +AEN L  +F    V   +E+ FS    RR
Sbjct:    5 VSPLPQTEILVY---WVLSFGSHLYSFFQLHKFSKEHEAGLSREFQLEKGLLQGFKRDSSDFEWSFWSD-WGRKSLLLTLIGHCVVSRL-SGYFYPK---FKVLAITLYGLLAAVSVLGVKGVSVLLVHLSVTFLVAQL-QKPAMSWMCNLLLIATLYIQPIQEIQKSWYMTEEEYYLLLFSVAVCSLRFISFSLEQCWSSCNALVQLFWLLAYTFYHPFFYNGPIMTYKAFTEQMQRSTEENNRTTFAFSHLLLRSGRILLWWCLAE-CLIHF-MYMHSIQSNETYIEILPPWALGGLALALVQFFYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLH--KLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRR 430          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001671.1 (SMESG000001671.1)

HSP 1 Score: 927.932 bits (2397), Expect = 0.000e+0
Identity = 474/504 (94.05%), Postives = 482/504 (95.63%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630
            TKCEREKQKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFL+NGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLI+WYFNYYYSSAKFFQMEVLIFLTFAIAGLFR KSLIWIIGCLSLYSMKYMPDYSFYK  YLFHNS+PYLAVLFTRAISVGL ISEAP+YDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTH WQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMW             HVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQY AENILKYIFLFTWVGPYLEKTFSPIWLRRLIAAAVAASF SSVWAFA FQYGI IANALYFSSLNKNLSW+VERFITGSAFIYSHAQISLTVNEYLRKRKLKTA
Sbjct:   25 TKCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLENGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLISWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRQKSLIWIIGCLSLYSMKYMPDYSFYKDDYLFHNSYPYLAVLFTRAISVGLAISEAPRYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHYWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMW------------SHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTWVGPYLEKTFSPIWLRRLIAAAVAASFLSSVWAFAVFQYGISIANALYFSSLNKNLSWIVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 516          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1)

HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 333/339 (98.23%), Postives = 336/339 (99.12%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 1135
            TKCERE QKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMP YSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTI THDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR
Sbjct:   25 TKCERENQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 363          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1)

HSP 1 Score: 532.332 bits (1370), Expect = 0.000e+0
Identity = 259/262 (98.85%), Postives = 260/262 (99.24%), Query Frame = 2
Query:  350 MELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 1135
            MELFV+GAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMP YSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTI THDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR
Sbjct:    1 MELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 262          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001542.1 (SMESG000001542.1)

HSP 1 Score: 460.685 bits (1184), Expect = 1.140e-157
Identity = 233/503 (46.32%), Postives = 342/503 (67.99%), Query Frame = 2
Query:  122 KCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630
            K ER + KDY++P ISK+E    L+IW   +L+G Y+ YKL   KKT + F K   I    FGLY S  +  WDEL++L      P   Y+ +SKL R   SP + M  N ++   FNYYYSS KF  ME++IFL  A+ GLF+ K+L+WI G   LY ++Y+  Y F+   ++F +++PY  +L TR+IS+GLTI+++ K D K  LEM ++++YFPAI+GCR+M +K+F+  IYKP +I +WK W     ++  Y  +W+ +  + H+ L + TH+ +  H V   G Q+F G+H+YMVY++FY+ ++L+TQLDGFLT  GPECI HI LYSRMW+NFD  LH+WLK+++FRP+ KLG F +T++FA  A F FV  FHG++ +N+ WI++++FQY +EN+LK+++L T  G  +E+ FSPI +RR+IA + A SF  S++AFA+F +G+ +AN++YFS    +L+ L  R      F Y+H+Q+SLTVNEYLRKRK K +
Sbjct:    9 KDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVIMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSDSKSFLEMLYFYFYFPAIVGCRMMNVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQINNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKSKDS 511          
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Match: SMESG000001654.1 (SMESG000001654.1)

HSP 1 Score: 262.692 bits (670), Expect = 1.250e-83
Identity = 150/159 (94.34%), Postives = 153/159 (96.23%), Query Frame = 2
Query: 1154 HLWLKDHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIWLRRLIXXXXXXXXXXXXXXXXXXQYGIPIANALYFSSLNKNLSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 1630
            +L +  HVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQY AENILKYIFLFT VGPYLEKTFSPIWLRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNK+ SWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA
Sbjct:  135 NLLITCHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTCVGPYLEKTFSPIWLRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNKSFSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 293          

HSP 2 Score: 231.106 bits (588), Expect = 1.736e-71
Identity = 111/115 (96.52%), Postives = 114/115 (99.13%), Query Frame = 2
Query:  119 TKCEREKQKDYDVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDELMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLIT 463
            TKCEREKQKDY+VPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLW+ELMELFV+GAVPFTFYI ISKLLRSYTSPKMFMFGNLLIT
Sbjct:   25 TKCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIIISKLLRSYTSPKMFMFGNLLIT 139          
The following BLAST results are available for this feature:
BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HHAT5.104e-826.35hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT5.104e-826.35hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT6.787e-826.43hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT6.787e-826.43hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT7.365e-827.52hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hhat-16.068e-1527.08Homolog of Hedgehog AcylTransferase [Source:UniPr... [more]
hhat-23.343e-1236.28Homolog of Hedgehog AcylTransferase [Source:UniPr... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rasp6.106e-720.10gene:FBgn0024194 transcript:FBtr0073029[more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hhat4.866e-924.88hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
HHAT2.002e-825.53hedgehog acyltransferase [Source:NCBI gene;Acc:100... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Hhat5.745e-925.00hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
Hhat6.817e-926.24hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
Hhat6.991e-926.24hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q8BMT9|HHAT_MOUSE4.018e-825.00Protein-cysteine N-palmitoyltransferase HHAT OS=Mu... [more]
sp|Q9VZU2|HHAT_DROME6.121e-620.10Protein-cysteine N-palmitoyltransferase Rasp OS=Dr... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0V0RNH63.361e-1923.73Protein-cysteine N-palmitoyltransferase HHAT OS=Tr... [more]
A0A0V1CGW53.004e-1823.73Protein-cysteine N-palmitoyltransferase HHAT OS=Tr... [more]
A0A0V0UPL83.405e-1823.73Protein-cysteine N-palmitoyltransferase HHAT OS=Tr... [more]
A0A1Y3ES493.405e-1823.73MBOAT family protein OS=Trichinella nativa OX=6335... [more]
A0A0V1EAM25.973e-1823.49Protein-cysteine N-palmitoyltransferase HHAT OS=Tr... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hhat3.409e-1030.84hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO331406.014e-1126.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO381505.973e-1024.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hhat1.169e-721.64hedgehog acyltransferase [Source:NCBI gene;Acc:101... [more]
hhat1.407e-721.64hedgehog acyltransferase [Source:NCBI gene;Acc:101... [more]
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BLAST of Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein) vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000001671.10.000e+094.05SMESG000001671.1[more]
SMESG000001665.10.000e+098.23SMESG000001665.1[more]
SMESG000001665.10.000e+098.85SMESG000001665.1[more]
SMESG000001542.11.140e-15746.32SMESG000001542.1[more]
SMESG000001654.11.250e-8394.34SMESG000001654.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032865 ID=SMED30032865|Name=Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein)|organism=Schmidtea mediterranea sexual|type=transcript|length=1672bp
CTATTTAAATTTGGTTTTCTTGTTGAATTTAAAACAATAATTGATAATGT
CCAAAATAACAAATGAGGAATCGATTGAAAAAGAAAACAAGAGCGAAAAA
GAAAGTGTCCCAGAAGAAACTAAATGTGAACGTGAAAAGCAGAAAGATTA
TGACGTCCCTCCAATATCAAAATTAGAATTTGCATTTTATTTACTCATTT
GGGTATTTATTGTTTTGAGAGGTGTTTATGAAATCTACAAGCTTACCAAC
AATAAGAAAACACAAAAACAGTTCTTGAAAAATGGATTTATACAAAAGGG
CTCATTCGGATTGTATAAAAGCAATAATGAATACCTATGGGATGAATTAA
TGGAGTTGTTTGTCAGGGGTGCAGTGCCTTTTACGTTTTATATATTCATT
TCCAAACTTTTAAGGTCATATACGTCACCGAAAATGTTTATGTTCGGAAA
CTTATTAATAACATGGTATTTCAATTATTATTATTCATCGGCAAAATTTT
TTCAAATGGAAGTTCTAATTTTTCTAACTTTTGCAATAGCCGGTTTATTC
AGGCATAAAAGTTTAATATGGATCATAGGTTGCTTATCGCTTTATTCAAT
GAAATATATGCCTGATTACTCTTTTTATAAACAATATTACCTTTTTCATA
ATTCATTTCCTTATTTGGCTGTTCTATTCACTCGGGCGATTTCTGTTGGT
TTGACGATTTCTGAAGCACCCAAATATGACATGAAACTCGTTTTGGAAAT
GTCATTTTACTTTTGGTATTTTCCAGCTATAATTGGATGCCGATTGATGG
TGATCAAAGAATTTATAAACAATATTTATAAACCGTGTGTCATTGAAGAT
TGGAAGGAATGGTTGTTCAGTTCTGTCCGTATTGCTGCATATATATTTAT
TTGGAATATAGTAATGCACTACTGTCACATTTATTTAACCATTGTTACTC
ATGACTGGCAAAATAAGCATATCGTGGTCGCTTGCGGAGTTCAGATGTTC
TATGGAATACATTATTATATGGTCTATATTATCTTTTATAAGTCGTCATA
CCTTATAACACAATTGGATGGATTTTTAACTGCCCCTGGACCAGAATGCA
TTGTCCATATTGCCTTATATTCGCGAATGTGGAGAAATTTCGATGTTGCT
CTACATCTTTGGCTAAAAGATCATGTGTTTCGCCCCATAGCCAAACTCGG
TCCATTTAGAATAACTAGATATTTCGCTGCGATTGCCTGCTTTGCATTTG
TTGTAAACTTCCATGGACTGAGAAGAGATAATTTATATTGGATTTCATTG
AGTATATTTCAATACATGGCAGAAAATATTCTCAAATACATTTTCCTGTT
TACATGGGTTGGACCATATCTAGAGAAAACTTTTTCCCCAATTTGGCTTC
GGCGATTAATTGCAGCAGCAGTAGCAGCGAGTTTTTATTCGTCAGTTTGG
GCTTTTGCTGCTTTTCAATATGGGATCCCAATTGCTAATGCTCTGTATTT
TAGCAGTTTAAACAAAAATCTTTCATGGCTAGTTGAAAGATTTATCACAG
GTTCTGCTTTTATCTATTCCCATGCTCAAATTTCACTGACAGTAAATGAG
TATCTTCGTAAAAGAAAATTGAAAACAGCATAATTTAGAACAAAAGTTGT
AGTATTTTTATGGTGTTTGTTG
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protein sequence of SMED30032865-orf-1

>SMED30032865-orf-1 ID=SMED30032865-orf-1|Name=SMED30032865-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=529bp
MSKITNEESIEKENKSEKESVPEETKCEREKQKDYDVPPISKLEFAFYLL
IWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWDE
LMELFVRGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAK
FFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPDYSFYKQYYLF
HNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRL
MVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIV
THDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPE
CIVHIALYSRMWRNFDVALHLWLKDHVFRPIAKLGPFRITRYFAAIACFA
FVVNFHGLRRDNLYWISLSIFQYMAENILKYIFLFTWVGPYLEKTFSPIW
LRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNKNLSWLVERFI
TGSAFIYSHAQISLTVNEYLRKRKLKTA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000232copulatory apparatus
PLANA:0002089reproductive organ
PLANA:0003117parapharyngeal cell
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR13285:SF18PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASPcoord: 5..493
NoneNo IPR availablePANTHERPTHR13285ACYLTRANSFERASEcoord: 5..493
NoneNo IPR availableTMHMMTMhelixcoord: 254..276
NoneNo IPR availableTMHMMTMhelixcoord: 206..228
NoneNo IPR availableTMHMMTMhelixcoord: 20..39
NoneNo IPR availableTMHMMTMhelixcoord: 130..152
NoneNo IPR availableTMHMMTMhelixcoord: 283..305
NoneNo IPR availableTMHMMTMhelixcoord: 106..123
NoneNo IPR availableTMHMMTMhelixcoord: 71..93
NoneNo IPR availableTMHMMTMhelixcoord: 425..447
NoneNo IPR availableTMHMMTMhelixcoord: 172..194
NoneNo IPR availableTMHMMTMhelixcoord: 364..383
NoneNo IPR availableTMHMMTMhelixcoord: 388..410