Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032861 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: DSTYK (dual serine/threonine and tyrosine protein kinase [Source:HGNC Symbol;Acc:HGNC:29043]) HSP 1 Score: 173.711 bits (439), Expect = 8.409e-44 Identity = 137/517 (26.50%), Postives = 239/517 (46.23%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D +MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + T + W+ + + LAK+IC+ LN H+ F +L + + +E + ++ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N I + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 395 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEF-KDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLE-----WKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCASK--DHLWNNVRRGARPERLPVFDEECWQLMEACWD 890
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: DSTYK (dual serine/threonine and tyrosine protein kinase [Source:HGNC Symbol;Acc:HGNC:29043]) HSP 1 Score: 126.331 bits (316), Expect = 5.955e-29 Identity = 121/516 (23.45%), Postives = 216/516 (41.86%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D +MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + T + W+ + + LAK+IC+ LN H+ F +L + + +E + ++ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N I + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ RPERL + W LM CWD
Sbjct: 395 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEF-KDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLE-----WKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-----------------------------------------------TGARPERLPVFDEECWQLMEACWD 845
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:HGNC Symbol;Acc:HGNC:6851]) HSP 1 Score: 98.9821 bits (245), Expect = 2.398e-21 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 129 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 348
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:HGNC Symbol;Acc:HGNC:6851]) HSP 1 Score: 97.4413 bits (241), Expect = 6.959e-20 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 381
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:HGNC Symbol;Acc:HGNC:6851]) HSP 1 Score: 97.4413 bits (241), Expect = 6.959e-20 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 381
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZK622.1 (Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;Acc:Q23554]) HSP 1 Score: 89.7373 bits (221), Expect = 1.523e-18 Identity = 77/315 (24.44%), Postives = 150/315 (47.62%), Query Frame = 3
Query: 1917 LNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVE-KEMIGQGSQGTVYRCV--CNG-KEYAKKKI------IVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK--KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA-------LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWDQ 2804
L K D ++ E++F+ + +++ T+R K +++ LL+ ++ Q L D ++ +M+G+G+ G VY+ C G K K+ I ++E + +E ++HPN++ V V +E++ L ++++K KN ++L +LK S + + L+Y+H +HRD+ N L+ +N V + D+G K L+ L + +APE++ + Y K D+YSFG+LLW + P + + VK ++ + P+R+ N+ ++++CW Q
Sbjct: 82 LQEKEDGSIVIEERKFESV---LDMVTTLRMKRLPVSANCPALLLNPINKQDWELRHDQIKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGAL-----DSFLKNEKNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLM-HKNVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWEIFMDGAIP--YPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNI--MISQCWPQ 383
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: svh-2 (Tyrosine-protein kinase receptor svh-2 [Source:UniProtKB/Swiss-Prot;Acc:H2KZU7]) HSP 1 Score: 91.6633 bits (226), Expect = 1.582e-18 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 3
Query: 2109 IGQGSQGTVYRCVCNGKEYAKKKII---VPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK--KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTF-----VHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLW-DLMNECW 2798
IGQG G VY+ + + + ++K++ + + EE F+HPN+L LI V ++D+ I I+ Y + K DL+++++ +N + + + + ++A + Y+H++ +HRDL N LLDE V +AD+G C+ + + +V V P + + + DI+SFG+++W L P ++N S + + ++ R + P+ L+ D+M CW
Sbjct: 741 IGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPII-ITEY--MAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTP--YSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACW 976
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: svh-2 (Tyrosine-protein kinase receptor svh-2 [Source:UniProtKB/Swiss-Prot;Acc:H2KZU7]) HSP 1 Score: 91.6633 bits (226), Expect = 1.750e-18 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 3
Query: 2109 IGQGSQGTVYRCVCNGKEYAKKKII---VPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK--KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTF-----VHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLW-DLMNECW 2798
IGQG G VY+ + + + ++K++ + + EE F+HPN+L LI V ++D+ I I+ Y + K DL+++++ +N + + + + ++A + Y+H++ +HRDL N LLDE V +AD+G C+ + + +V V P + + + DI+SFG+++W L P ++N S + + ++ R + P+ L+ D+M CW
Sbjct: 741 IGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPII-ITEY--MAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTP--YSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACW 976
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: svh-2 (Tyrosine-protein kinase receptor svh-2 [Source:UniProtKB/Swiss-Prot;Acc:H2KZU7]) HSP 1 Score: 91.6633 bits (226), Expect = 1.750e-18 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 3
Query: 2109 IGQGSQGTVYRCVCNGKEYAKKKII---VPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK--KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTF-----VHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLW-DLMNECW 2798
IGQG G VY+ + + + ++K++ + + EE F+HPN+L LI V ++D+ I I+ Y + K DL+++++ +N + + + + ++A + Y+H++ +HRDL N LLDE V +AD+G C+ + + +V V P + + + DI+SFG+++W L P ++N S + + ++ R + P+ L+ D+M CW
Sbjct: 741 IGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPII-ITEY--MAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTP--YSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACW 976
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: svh-2 (Tyrosine-protein kinase receptor svh-2 [Source:UniProtKB/Swiss-Prot;Acc:H2KZU7]) HSP 1 Score: 91.2781 bits (225), Expect = 1.965e-18 Identity = 63/241 (26.14%), Postives = 120/241 (49.79%), Query Frame = 3
Query: 2109 IGQGSQGTVYRCVCNGKEYAKKKII---VPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK--KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTF-----VHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLW-DLMNECW 2798
IGQG G VY+ + + + ++K++ + + EE F+HPN+L LI V ++D+ I I+ Y + K DL+++++ +N + + + + ++A + Y+H++ +HRDL N LLDE V +AD+G C+ + + +V V P + + + DI+SFG+++W L P ++N S + + ++ R + P+ L+ D+M CW
Sbjct: 741 IGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPII-ITEY--MAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTP--YSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACW 976
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0090002) HSP 1 Score: 95.9005 bits (237), Expect = 1.636e-20 Identity = 75/254 (29.53%), Postives = 129/254 (50.79%), Query Frame = 3
Query: 2100 KEMIGQGSQGTVYRCVC--NGKEYAKKKIIV----------PTDLLETISEEVY-YSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLK-ISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSN--YSFVGTFVHIAPEIVR------QSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
KE++G+G TV RC+ GKE+A K I + P +LE +E+ + HP ++ L V +D F E+ K +L +Y+ + E++ + I ++ ++YIH ++I+HRDLK NILLDE +NV + D+GF K L + GT ++APE ++ Y Q++DI++ G++++ L G C PP + Q ++ ++E PE +I ++ DL+ +C
Sbjct: 26 KEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELC-----PKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG-C-PPFWHRKQMVMLRNIMEGKYSFTSPE-WADISEDPKDLIRKC 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0343648) HSP 1 Score: 95.9005 bits (237), Expect = 1.636e-20 Identity = 75/254 (29.53%), Postives = 129/254 (50.79%), Query Frame = 3
Query: 2100 KEMIGQGSQGTVYRCVC--NGKEYAKKKIIV----------PTDLLETISEEVY-YSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLK-ISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSN--YSFVGTFVHIAPEIVR------QSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
KE++G+G TV RC+ GKE+A K I + P +LE +E+ + HP ++ L V +D F E+ K +L +Y+ + E++ + I ++ ++YIH ++I+HRDLK NILLDE +NV + D+GF K L + GT ++APE ++ Y Q++DI++ G++++ L G C PP + Q ++ ++E PE +I ++ DL+ +C
Sbjct: 26 KEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELC-----PKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG-C-PPFWHRKQMVMLRNIMEGKYSFTSPE-WADISEDPKDLIRKC 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0343587) HSP 1 Score: 95.5153 bits (236), Expect = 1.722e-20 Identity = 75/254 (29.53%), Postives = 129/254 (50.79%), Query Frame = 3
Query: 2100 KEMIGQGSQGTVYRCVC--NGKEYAKKKIIV----------PTDLLETISEEVY-YSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLK-ISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSN--YSFVGTFVHIAPEIVR------QSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
KE++G+G TV RC+ GKE+A K I + P +LE +E+ + HP ++ L V +D F E+ K +L +Y+ + E++ + I ++ ++YIH ++I+HRDLK NILLDE +NV + D+GF K L + GT ++APE ++ Y Q++DI++ G++++ L G C PP + Q ++ ++E PE +I ++ DL+ +C
Sbjct: 26 KEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELC-----PKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG-C-PPFWHRKQMVMLRNIMEGKYSFTSPE-WADISEDPKDLIRKC 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 94.7449 bits (234), Expect = 1.605e-19 Identity = 53/134 (39.55%), Postives = 78/134 (58.21%), Query Frame = 3
Query: 2403 EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNY---SFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
EV L Y+H++ +HRD+K AN+LL EQ +V LAD+G L + +FVGT +APE+++QS+YD K DI+S G+ LAKG EPP N + ++VL + KN P+ G+ + D + C
Sbjct: 116 EVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKG--EPP---NSELHPMRVLFLIP-KNNPPQLTGSYTKSFKDFVEAC 243
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0301501) HSP 1 Score: 94.3597 bits (233), Expect = 1.625e-19 Identity = 77/256 (30.08%), Postives = 131/256 (51.17%), Query Frame = 3
Query: 2100 KEMIGQGSQGTVYRCVC--NGKEYAKKKIIV----------PTDLLETISEEVY-YSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLK-ISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA----LSNYSFVGTFVHIAPEIVR------QSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
KE++G+G TV RC+ GKE+A K I + P +LE +E+ + HP ++ L V +D F E+ K +L +Y+ + E++ + I ++ ++YIH ++I+HRDLK NILLDE +NV + D+GF K L L+N GT ++APE ++ Y Q++DI++ G++++ L G C PP + Q ++ ++E PE +I ++ DL+ +C
Sbjct: 26 KEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFEL-----CPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTN--LCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG-C-PPFWHRKQMVMLRNIMEGKYSFTSPE-WADISEDPKDLIRKC 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:402922]) HSP 1 Score: 154.836 bits (390), Expect = 5.373e-38 Identity = 135/536 (25.19%), Postives = 243/536 (45.34%), Query Frame = 3
Query: 1254 VDFTNENLDEIF-TMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLM------KDSVEKEMIGQGSQGTVYRC-VCNGKEYAKKKIIVPTD--LLETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+++T E E+F ++ + R ++K I + + ++L++ N ++F I+ + + K+ K C I DLI L+ + N ++++ LE C + + K SC + S + L++ L Y ++ + + W +K II + + T + W+ + + LAK+IC+ LN H+ F +L + + + +E + ++ + + + L L+S+ L K + +E+ G+G G VY C G+ K +VP D ++ E +Y+ L +H L+ L ++ + I + + + DL +K L+L+++L I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WYL G + P F C S L K RPERL + W LM CW+
Sbjct: 351 LEYTREKEGELFCSLMAIANRKQEEMKEMIVETLSSMKEQLLEDAQN-----------LDFTDIIMSSNGEPVSSKDIKVCISQIQDLIVNRLNQAVANKLTNSVDYLRESFVGTLERCLGS------LEKSTPESCAHNVTSNH---LKQILNAAYHVEVTFHSGSSVTRLFWEQIKQIIHRITWVNPPAITAE-----WKRKVAQDAIESLSAAKLAKSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAP----RLARLSLESRSLRDILLHGKPKLGREL-GRGQYGVVYLCDSWAGRHPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAG-LSLKERLLIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYLCSGSVKLPEAFEKCASK--DQLWTNVKKGCRPERLPVFDEECWQLMEACWN 852
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:402922]) HSP 1 Score: 148.673 bits (374), Expect = 3.702e-36 Identity = 99/319 (31.03%), Postives = 163/319 (51.10%), Query Frame = 3
Query: 1881 LAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLM------KDSVEKEMIGQGSQGTVYRC-VCNGKEYAKKKIIVPTD--LLETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
LAK+IC+ LN H+ F +L + + + +E + ++ + + + L L+S+ L K + +E+ G+G G VY C G+ K +VP D ++ E +Y+ L +H L+ L ++ + I + + + DL +K L+L+++L I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WYL G + P F C S L K RPERL + W LM CW+
Sbjct: 515 LAKSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAPR----LARLSLESRSLRDILLHGKPKLGREL-GRGQYGVVYLCDSWAGRHPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAG-LSLKERLLIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYLCSGSVKLPEAFEKCASK--DQLWTNVKKGCRPERLPVFDEECWQLMEACWN 824
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: mos (v-mos Moloney murine sarcoma viral oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-040428-3]) HSP 1 Score: 97.4413 bits (241), Expect = 2.431e-21 Identity = 80/259 (30.89%), Postives = 127/259 (49.03%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYL----FEHPNLLPLIAVTV--------NDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYS--------FVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGN------IPDNLWDLMNECWD 2801
E IG G GTV+R G+ A KK+ + L S + +++ L H N++ ++A T DNI +E + L K+ Y ++L +E+ +K S+++A AL+++H ++H DLK AN+LL EQ +AD+G C S +S+ S GTF H APE+++ + ++D+YSFG+ +W L EPP + Q +L V N+RP N I L++ CWD
Sbjct: 64 EPIGSGGFGTVFRGTYFGETVAVKKVKCVKNKLA--SRQSFWAELNAAHLHHQNIVRVLAATTCTPAHLNTKDNIGTIVMEFAGNINLQKLI---YGLTDLLPVEKCIKYSIDIARALQHLHAHGVVHLDLKPANVLLSEQGVCKIADFG-C-SFKISSTSDTVTHMNEIGGTFTHRAPELLKGEEVSPRVDVYSFGITMWQLLTR--EPPYEGDRQ----YILYAVVAYNLRPSTSRNVFTQSSIGQTCQKLISRCWD 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: mos (v-mos Moloney murine sarcoma viral oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-040428-3]) HSP 1 Score: 97.4413 bits (241), Expect = 2.431e-21 Identity = 80/259 (30.89%), Postives = 127/259 (49.03%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYL----FEHPNLLPLIAVTV--------NDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYS--------FVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGN------IPDNLWDLMNECWD 2801
E IG G GTV+R G+ A KK+ + L S + +++ L H N++ ++A T DNI +E + L K+ Y ++L +E+ +K S+++A AL+++H ++H DLK AN+LL EQ +AD+G C S +S+ S GTF H APE+++ + ++D+YSFG+ +W L EPP + Q +L V N+RP N I L++ CWD
Sbjct: 64 EPIGSGGFGTVFRGTYFGETVAVKKVKCVKNKLA--SRQSFWAELNAAHLHHQNIVRVLAATTCTPAHLNTKDNIGTIVMEFAGNINLQKLI---YGLTDLLPVEKCIKYSIDIARALQHLHAHGVVHLDLKPANVLLSEQGVCKIADFG-C-SFKISSTSDTVTHMNEIGGTFTHRAPELLKGEEVSPRVDVYSFGITMWQLLTR--EPPYEGDRQ----YILYAVVAYNLRPSTSRNVFTQSSIGQTCQKLISRCWD 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: mos (v-mos Moloney murine sarcoma viral oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-040428-3]) HSP 1 Score: 97.4413 bits (241), Expect = 2.431e-21 Identity = 80/259 (30.89%), Postives = 127/259 (49.03%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYL----FEHPNLLPLIAVTV--------NDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYS--------FVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGN------IPDNLWDLMNECWD 2801
E IG G GTV+R G+ A KK+ + L S + +++ L H N++ ++A T DNI +E + L K+ Y ++L +E+ +K S+++A AL+++H ++H DLK AN+LL EQ +AD+G C S +S+ S GTF H APE+++ + ++D+YSFG+ +W L EPP + Q +L V N+RP N I L++ CWD
Sbjct: 64 EPIGSGGFGTVFRGTYFGETVAVKKVKCVKNKLA--SRQSFWAELNAAHLHHQNIVRVLAATTCTPAHLNTKDNIGTIVMEFAGNINLQKLI---YGLTDLLPVEKCIKYSIDIARALQHLHAHGVVHLDLKPANVLLSEQGVCKIADFG-C-SFKISSTSDTVTHMNEIGGTFTHRAPELLKGEEVSPRVDVYSFGITMWQLLTR--EPPYEGDRQ----YILYAVVAYNLRPSTSRNVFTQSSIGQTCQKLISRCWD 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205]) HSP 1 Score: 151.369 bits (381), Expect = 7.182e-37 Identity = 135/521 (25.91%), Postives = 240/521 (46.07%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKV-----IQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L+ L + + L D +++ L++ + +++ A+M+F K I IP+N + + + K C I +LI L+ + N ++++ LE C + + + S +++ L++ L Y ++ + +W + II + + +S T + W+ + + LAK+IC+ L H+ F +L K+ +V ++K +L +R + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ + I + + T + DL +K L+LE +L+I+L+V ++++HNQ ++HRD+KL N+LLD+++ + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L K RPERL + W LM CW+
Sbjct: 327 RQKENELYESLMRISDRKQEELKDMIVETLNSMREQLLEDAANMQF-KDIAIPQNGEPVSVQEVKCCIFQIKELIISRLNQAVVNKLISSVDYLRESFVGTLERCLRS-----LEKSQQESSSHVTSNH-----LKQILNAAYHVEVTFNSGSTVTRMVWEQIVQIIQRI--TWVSPPTI---TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASL-KQLEVGHSGRLEKTNDLWLRVR---KDHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTG-LSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGKYDNSVDVYAFGILFWYICSGSVKLPEAFEKCASK--DHLWNNVRKGARPERLAIFDEECWKLMEACWN 823
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205]) HSP 1 Score: 151.369 bits (381), Expect = 7.881e-37 Identity = 135/521 (25.91%), Postives = 240/521 (46.07%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKV-----IQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRF-DCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L+ L + + L D +++ L++ + +++ A+M+F K I IP+N + + + K C I +LI L+ + N ++++ LE C + + + S +++ L++ L Y ++ + +W + II + + +S T + W+ + + LAK+IC+ L H+ F +L K+ +V ++K +L +R + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ + I + + T + DL +K L+LE +L+I+L+V ++++HNQ ++HRD+KL N+LLD+++ + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L K RPERL + W LM CW+
Sbjct: 306 RQKENELYESLMRISDRKQEELKDMIVETLNSMREQLLEDAANMQF-KDIAIPQNGEPVSVQEVKCCIFQIKELIISRLNQAVVNKLISSVDYLRESFVGTLERCLRS-----LEKSQQESSSHVTSNH-----LKQILNAAYHVEVTFNSGSTVTRMVWEQIVQIIQRI--TWVSPPTI---TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASL-KQLEVGHSGRLEKTNDLWLRVR---KDHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTG-LSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGKYDNSVDVYAFGILFWYICSGSVKLPEAFEKCASK--DHLWNNVRKGARPERLAIFDEECWKLMEACWN 802
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205]) HSP 1 Score: 151.754 bits (382), Expect = 8.172e-37 Identity = 135/521 (25.91%), Postives = 240/521 (46.07%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKV-----IQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L+ L + + L D +++ L++ + +++ A+M+F K I IP+N + + + K C I +LI L+ + N ++++ LE C + + + S +++ L++ L Y ++ + +W + II + + +S T + W+ + + LAK+IC+ L H+ F +L K+ +V ++K +L +R + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ + I + + T + DL +K L+LE +L+I+L+V ++++HNQ ++HRD+KL N+LLD+++ + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L K RPERL + W LM CW+
Sbjct: 390 RQKENELYESLMRISDRKQEELKDMIVETLNSMREQLLEDAANMQF-KDIAIPQNGEPVSVQEVKCCIFQIKELIISRLNQAVVNKLISSVDYLRESFVGTLERCLRS-----LEKSQQESSSHVTSNH-----LKQILNAAYHVEVTFNSGSTVTRMVWEQIVQIIQRI--TWVSPPTI---TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASL-KQLEVGHSGRLEKTNDLWLRVR---KDHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTG-LSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGKYDNSVDVYAFGILFWYICSGSVKLPEAFEKCASK--DHLWNNVRKGARPERLAIFDEECWKLMEACWN 886
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205]) HSP 1 Score: 151.369 bits (381), Expect = 8.938e-37 Identity = 135/521 (25.91%), Postives = 240/521 (46.07%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKV-----IQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L+ L + + L D +++ L++ + +++ A+M+F K I IP+N + + + K C I +LI L+ + N ++++ LE C + + + S +++ L++ L Y ++ + +W + II + + +S T + W+ + + LAK+IC+ L H+ F +L K+ +V ++K +L +R + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ + I + + T + DL +K L+LE +L+I+L+V ++++HNQ ++HRD+KL N+LLD+++ + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L K RPERL + W LM CW+
Sbjct: 391 RQKENELYESLMRISDRKQEELKDMIVETLNSMREQLLEDAANMQF-KDIAIPQNGEPVSVQEVKCCIFQIKELIISRLNQAVVNKLISSVDYLRESFVGTLERCLRS-----LEKSQQESSSHVTSNH-----LKQILNAAYHVEVTFNSGSTVTRMVWEQIVQIIQRI--TWVSPPTI---TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASL-KQLEVGHSGRLEKTNDLWLRVR---KDHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTG-LSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGKYDNSVDVYAFGILFWYICSGSVKLPEAFEKCASK--DHLWNNVRKGARPERLAIFDEECWKLMEACWN 887
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205]) HSP 1 Score: 151.369 bits (381), Expect = 9.096e-37 Identity = 135/521 (25.91%), Postives = 240/521 (46.07%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKV-----IQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L+ L + + L D +++ L++ + +++ A+M+F K I IP+N + + + K C I +LI L+ + N ++++ LE C + + + S +++ L++ L Y ++ + +W + II + + +S T + W+ + + LAK+IC+ L H+ F +L K+ +V ++K +L +R + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ + I + + T + DL +K L+LE +L+I+L+V ++++HNQ ++HRD+KL N+LLD+++ + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L K RPERL + W LM CW+
Sbjct: 374 RQKENELYESLMRISDRKQEELKDMIVETLNSMREQLLEDAANMQF-KDIAIPQNGEPVSVQEVKCCIFQIKELIISRLNQAVVNKLISSVDYLRESFVGTLERCLRS-----LEKSQQESSSHVTSNH-----LKQILNAAYHVEVTFNSGSTVTRMVWEQIVQIIQRI--TWVSPPTI---TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASL-KQLEVGHSGRLEKTNDLWLRVR---KDHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTG-LSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGKYDNSVDVYAFGILFWYICSGSVKLPEAFEKCASK--DHLWNNVRKGARPERLAIFDEECWKLMEACWN 870
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Dstyk (dual serine/threonine and tyrosine protein kinase [Source:MGI Symbol;Acc:MGI:1925064]) HSP 1 Score: 176.407 bits (446), Expect = 9.450e-45 Identity = 138/517 (26.69%), Postives = 242/517 (46.81%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D A+MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + + T + W+ + ++ LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N + + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 393 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDAANMEF-KDVIVPENGETIGTREIKSCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITLE-----WKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSIKLPEAFERCASK--DHLWNNVRRGTRPERLPVFDEECWQLMEACWD 888
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Dstyk (dual serine/threonine and tyrosine protein kinase [Source:MGI Symbol;Acc:MGI:1925064]) HSP 1 Score: 129.798 bits (325), Expect = 3.524e-30 Identity = 122/516 (23.64%), Postives = 219/516 (42.44%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D A+MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + + T + W+ + ++ LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N + + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ RPERL + W LM CWD
Sbjct: 393 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDAANMEF-KDVIVPENGETIGTREIKSCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITLE-----WKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-----------------------------------------------TGTRPERLPVFDEECWQLMEACWD 843
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:MGI Symbol;Acc:MGI:1346881]) HSP 1 Score: 97.0561 bits (240), Expect = 5.097e-20 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 381
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:MGI Symbol;Acc:MGI:1346881]) HSP 1 Score: 97.0561 bits (240), Expect = 5.097e-20 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 381
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:MGI Symbol;Acc:MGI:1346881]) HSP 1 Score: 97.0561 bits (240), Expect = 5.097e-20 Identity = 65/240 (27.08%), Postives = 118/240 (49.17%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYM-----KKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ DL ET ++ + +HPN++ V C + Y LM+ + + +T + S+ +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + PD L+ +CW+
Sbjct: 162 QWVGSGAQGAVFLGRFHGEEVAVKKV---RDLKET---DIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YKDVDSSA--IIWGVGSNSLHLPVPSSCPDGFKILLRQCWN 381
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6XUX0|DUSTY_CHICK (Dual serine/threonine and tyrosine protein kinase OS=Gallus gallus OX=9031 GN=DSTYK PE=2 SV=1) HSP 1 Score: 179.104 bits (453), Expect = 9.626e-45 Identity = 160/581 (27.54%), Postives = 265/581 (45.61%), Query Frame = 3
Query: 1152 LLENFEREILT-----ATKSLIDFQMDVLTKIISRA---KQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENC-------FEAHLSP-KIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEY-AKKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
LL F R++L A SL + L I++A ++ + T + L+ +T RK E L+ L + N + + D +++ L N + +++ A+MEF K IIIPEN + + K+ K C K I +LI L+ + N ++++ LE C +E + P + + K K S +++ L++ L Y ++ + +W +K II + T D W+ + + LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L +G+G G VY C G + K +VP D ++ E +Y L H L+ L ++ I + + + DL +K L LE +L+I+L+V ++Y+H+Q ++HRD+KL N+LLD++N + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + VRPERL + W LM CWD
Sbjct: 329 LLSTFSRQVLQKHLVEAATSLNEVHCRCLNIFINQAFDMQRDLQITPKRLE--YTRRK-ENELYESLMNIANRKQEEMKDMIIETLSNMKEELLEDAANMEF-KDIIIPENGEPVSSKDIKCCIKQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLKSLEESWEVSVHPARSLEKSKDVSVHITSNY-----LKQILNAAYHVEVTFHSGSTVTRMLWEQIKQIIQRITWVSPPAITSD-----WKRKVAQDAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEDGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHGKPKLGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLQSHERLVDLHGSVIDYGYGGGSSIAVLLIMERLHRDLYTGLKAG-LELETRLQIALDVVEGIRYLHSQGLVHRDIKLKNVLLDKKNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGHVKLPEAFERCASK--DHLWNNVRRGVRPERLPVFDEECWQLMEACWD 891
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4VSN4|DUSTY_CANLF (Dual serine/threonine and tyrosine protein kinase OS=Canis lupus familiaris OX=9615 GN=DSTYK PE=2 SV=1) HSP 1 Score: 176.407 bits (446), Expect = 5.575e-44 Identity = 140/517 (27.08%), Postives = 241/517 (46.62%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D + + L+ ++D A+MEF K +I+PEN +A + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + + T + W+ + ++ LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N I + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 397 RKKENELYESLMNIANRKQEEMKDMICETLNTMKGELLDDAANMEF-KDVIVPENGEAVGTRELKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSIHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITLE-----WKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLENTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCASK--DHLWNNVRRGARPERLPVFDEECWQLMEACWD 892
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q20CR4|DUSTY_MACMU (Dual serine/threonine and tyrosine protein kinase OS=Macaca mulatta OX=9544 GN=DSTYK PE=2 SV=1) HSP 1 Score: 176.407 bits (446), Expect = 6.199e-44 Identity = 139/517 (26.89%), Postives = 240/517 (46.42%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D A+MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + T + W+ + + LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N I + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 373 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDAANMEF-KDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLE-----WKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCASK--DHLWNNVRRGARPERLPVFDEECWQLMEACWD 868
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6XUX1|DUSTY_MOUSE (Dual serine/threonine and tyrosine protein kinase OS=Mus musculus OX=10090 GN=Dstyk PE=1 SV=1) HSP 1 Score: 176.407 bits (446), Expect = 6.610e-44 Identity = 138/517 (26.69%), Postives = 242/517 (46.81%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D A+MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + + T + W+ + ++ LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N + + + + DL +K LTLE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 393 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDAANMEF-KDVIVPENGETIGTREIKSCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITLE-----WKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSIKLPEAFERCASK--DHLWNNVRRGTRPERLPVFDEECWQLMEACWD 888
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6XUX2|DUSTY_RAT (Dual serine/threonine and tyrosine protein kinase OS=Rattus norvegicus OX=10116 GN=Dstyk PE=2 SV=1) HSP 1 Score: 175.252 bits (443), Expect = 1.628e-43 Identity = 137/517 (26.50%), Postives = 242/517 (46.81%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPEN-KAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYA-KKKIIVPTD--LLETISEEVYY-SYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
RK E L+ L + N + + D +++ L+ + ++D A+MEF K +I+PEN + + K C + I +LI L+ + N ++++ LE C ++ + K + S +++ L++ L Y ++ + + +W +K II + + T + W+ + ++ LAK+IC+ LN H+ F +L + + +E + K+ + L + + LQ L + + +G+G G VY C G + K +VP D ++ E +Y L +H L+ L ++ N + + + + DL +K L+LE +L+I+L+V ++++H+Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WY+ G + P F C S L + RPERL + W LM CWD
Sbjct: 393 RKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDAANMEF-KDVIVPENGETVGTREIKSCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQS------LEKSQDVSVHITSNY-----LKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITLE-----WKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAG-LSLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYICSGSIKLPEAFERCASK--DHLWNNVRRGTRPERLPVFDEECWQLMEACWD 888
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267FLZ4 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023032g1 PE=4 SV=1) HSP 1 Score: 314.309 bits (804), Expect = 8.006e-89 Identity = 247/834 (29.62%), Postives = 419/834 (50.24%), Query Frame = 3
Query: 393 PTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVN-IHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKT-AKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNK----IKSQETD------FHNEQFC-KFESDLNRIL---LENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAH-LSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWN---FLKNIIT--GLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKD-SVEKEM-IGQGSQGTVYRCVCNGKE--YAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVN----DNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQ-NNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEP-PLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
P I IVG K+GKS+ +N LL V Q+ CTAR+TR+TYS+ YV + + +QI + + L+ I + +V+L DEDR N + ++ + GIK +FL+ GID+IDSPGLNEN L+ L I+ LP++IYVID + + ++ ++K ++ + Y +T++D +E N + ++K + F KLQR I + C+ F S + + K IK + D N ++ +FE RIL + F I+ + L+ Q ++LT + RA + +N + ++ ++ +E+ + KS + ++ L+ + LI+D + +++ +S+I +A QK I ++ LI+ D + + + F+ H L + L + N +P L++ + Y L LK+ F I+ F+ I+T GL S + I W+ Q + L +K++L + + + L +H FL N+ ++++ + L+E R +I + L M T+D+ SKY + ++ E +G G+QG V+R + E A K+I+ L+ I+ EVY+S + EH NL+ ++ V ++ D R+ + IY LM D N M+++ L + Q+LKI LE+A AL+++H+ ++HRDLKLAN+L+ E V L+D+G KS N + VGT +++APE+VR Y D++S G+ LWYL +G + P + + +LL + + RP RL N+ D LWDLM CW
Sbjct: 85 PCIIIVGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGITIAVQKDLTTIKKTVLGAEVFYLVTKMDVSKDTEQEANQPAQEIEEEKAERVFSKLQRLGYISPNETRDT-CNKFLCVSCWKVRGFRRKKELMIKKNKLDPEALKEMENSKWVRRFEEVKTRILKFAQDQFRNLIVRSGDELMHIQSEILTLFMDRATNIKE-SNLRKEALYQIKSLEQETYQQSKSIVEKNRDELLRQAGLFFAERKPLILDEVRALKYSESVI----------SADMSQKDIEKKCVDEIHALIN----DRIIASFFDFFKNHGLKGFDLKNLMAELEKDVNPTPAYQVLKKTMLMSYSVSLEELKLSCLGFIIFKIKFFVIKIVTKPGLVFS----TSTPIQDPKWKKYQAEKYLEAINKNILVERLITWLKEWLEKQHREFLDNIASSEQLVESGMKLTEEERSEIKSLFPRVARLHMLTMDVISKYKYRGFRIDTEGNLGSGAQGEVFRVLNESGEPALAAKRIVSDEPSLDDIATEVYHSSVLEHDNLVHVVGVRLHKSKPDEKRWT---VEIYMELMCCDAWNLMQRHRLPVRQRLKIGLELAKALQFLHSSELIHRDLKLANVLVSEDLRQVKLSDFGLVKSTGFVNRTLVGTPIYLAPELVRGESYHTSADVFSLGIALWYLFEGTGKRHPEYVEIMPSVGAILL-ASALDCRPTRLPNMSDQLWDLMESCW 894
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267FM29 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021056g2 PE=4 SV=1) HSP 1 Score: 308.531 bits (789), Expect = 1.199e-86 Identity = 247/834 (29.62%), Postives = 417/834 (50.00%), Query Frame = 3
Query: 393 PTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVN-IHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLD-TDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSE-CHNFHGASLYSYMDYCNK----IKSQETD------FHNEQFC-KFESDLNRIL---LENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKY---DLLGLKIKNSSFSIWNFLKNII--TGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKD-SVEKEM-IGQGSQGTVYRCVCNGKE--YAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVN----DNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQ-NNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEP-PLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
P I IVG K+GKS+ +N LL V Q+ CTAR+TR+TYS+ YV + + +QI + + L+ I + +V+L DEDR N + ++ + GIK +FL+ GID+IDSPGLNEN L+ L I+ LP++IYVID + + ++ ++K ++ + Y +T++D + D + + ++K + F KLQR I + N E C+ F S + + K IK + D N ++ +FE RIL + F I+++ L Q ++LT + +A + ++ ++ +E+ +H KS + ++ L+ + LI+D + +++ +S+I + K K C I LI D +I +F + L C + K K+ Y + Y++ L++ L + Y D L + F I +F++ ++ GL LS T I + W+ Q + L K+ L + + ++ +H FL N+ ++++ + L+E R +I L M T+D+ SKY + ++ E +G G+QG V+R + E A K+I+ L+ I+ EVY+S + EH NL+ ++ V ++ D R+ + IY LM D N M+++ L + Q+LKI LE+A AL+++H+ ++HRD+KLAN+L+ E V L+D+G KS N + VGT +++APE+VR Y D++S G+ LWYL +G + P + + +LL + RP RL N+ D LWDLM CW
Sbjct: 85 PCIIIVGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGITVAVQKDLTTIKKTVLGAEVFYLVTKMDVSKDTEQEANRPAQEIEEEKAERVFSKLQRLGYI--SPNETKEKCNKFLCVSCWEVRRFRRKKELMIKKNKLDPEALKEMENSKWVRRFEEVKTRILKFAQDQFRNLIVSSGGGLRRIQSEILTLFMDKATNIKESNLRKKKALYQIKSLEQEIHQQSKSIVEKNRDELLRQAGLFFAERKPLILDEVRALKYSESVISADMS--QKDIEKKCVDEIHALIN---DRIIASFCDFLKDGALRLCLQEFDDLK--QKVAEYEKDVEQTPAYQV-LKKTLLEGYSLSSKDFLLGPLNVIIFRIKHFVRQMVRNPGLV---LSIST-PIQDQKWKEYQAEKYLGTISKENLVECLITSLKEWFEKQHREFLDNIASSEQLVESCMKLTEKERSEIKTLYPRVARLHMLTMDVISKYKYRGFRIDTEGNLGSGAQGEVFRVLNESGEPALAAKRIVSDEPSLDDIATEVYHSSVLEHDNLVHVVGVRLHKSKPDEKRWT---VEIYMELMCCDAWNLMQRHRLPVRQRLKIGLELAKALQFLHSSELIHRDVKLANVLVSEDLRQVKLSDFGLVKSTGFVNRTLVGTPIYLAPELVRGESYHTSADVFSLGIALWYLFEGTGKRHPEYVEIMPSVGAILL-AGALDCRPTRLPNMSDQLWDLMESCW 900
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267FZS1 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014911g1 PE=4 SV=1) HSP 1 Score: 304.679 bits (779), Expect = 4.676e-85 Identity = 234/843 (27.76%), Postives = 413/843 (48.99%), Query Frame = 3
Query: 390 NPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVN-IHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLD-TDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKI----------KSQET----------DFHNEQFCK-FESDLNRIL---LENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKN-AKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSN-DTF---DINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSV--EKEMIGQGSQGTVYRCVCNGKE--YAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVY-LADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWDQ 2804
P I I G K+GKS+ +N LL V Q+ CTAR+TR+TYS+ YV + + +QI + + L+ I + +V+L DEDR N + ++ + GIK +FL+ GID+IDSPGLNEN L+ L I+ LP++IYVID + V ++ +++ + I+Y IT++D D ++ + + + +K D F KLQR I K S C F S + + K K+ E+ + N ++ + FE RIL + F+ I+ A SL +LT + +A + ++ ++ +E +H KS + + + + + + LI+D + M + S+I ++ ++++ K C + I LI + +F++D + L CF K K+ Y + Y++ L++ L + Y L I S + F++NI + L R+ L + D F + W+ Q L D++ L + +++ + +H FL ++ +++K +++ R +I + LL M + ++Y ++ +G G+QG VY + E A KKI+ LE I+ E YYS + EHPN++ ++ + +N + + + +Y LM D M++ L+L ++L + L+++ AL+++H+ ++HRD+KLAN+L++ + V L+D+G K L ++ VGT ++++PE+VR+ Y DI+S G+ LWYL +G + P + T +VL + + RP RL D LW LM CWD+
Sbjct: 100 RPCIIIAGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGVTVAVQKDLQTIQKTASGAEILYLITKMDVADHLAAEMGREVAEMEAEKADHVFSKLQRLGYISKDATRQS-CRKFLCVSCWEVRRFRRKKEMIEKKMKKSKTAESGEKLMSDLVKEMENSKWVRQFEEVKRRILQFAQDQFKNLIVGAGSSLRAVHCQILTMFMDKAHDIKESNQRKKKALYQIKSLEHEIHQQSKSIVERHRGEFLAQANRFFAEKKPLILDEVRSMSYSDSVI---SEGMSQRDIEKKCIEEIHTLINDRIIATFSDFLRDNV---LRTCFTDFDDLK--EKVAEYEKDVEQTPAYQV-LKKTLLE--GYSLSSKAIVRGSVTC--FIRNIGSTL-RALLKHPDIFLGKAVQHHKWKEHQASQYLKNIDREKLVACLVSSIGEWFDKRHSDFLHSMSYSEVLVEKSYRMTDRERKEIIKLSPIVALLHMNAFAIITRYKFRNHRLDLDNCLGSGAQGRVYTVLSPTGEPVMAAKKIVTNRAGLEEIAAEAYYSSVLEHPNIVRVVGTVLLENAKHNGQWSVELYMELMHCDALTLMEQQRLSLAKRLWLGLQISKALEFLHSSQLIHRDVKLANLLVNSEATVAKLSDFGLLKGQGLVGHTLVGTPIYLSPELVRRENYGVSTDIFSLGIALWYLVEGSGQHHPDYVTNLKTVEEVLAATSERGCRPNRLPEASDQLWQLMVRCWDE 927
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1I8HCU5 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 303.138 bits (775), Expect = 8.099e-85 Identity = 237/830 (28.55%), Postives = 413/830 (49.76%), Query Frame = 3
Query: 393 PTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVN-IHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLD-TDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNK----IKSQETD------FHNEQFCK-FESDLNRIL---LENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYD--LLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKD-SVEKEM-IGQGSQGTVYRCVCNGKE--YAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVN----DNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQ-NNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEP-PLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
P I IVG K+GKS+ +N LL V Q+ CTAR+TR+TYS+ YV + + +QI + + L+ I + +V+L DEDR N + ++ + GIK +FL+ GID+IDSPGLNEN L+ L I+ LP++IYVID + + ++ ++K ++ + Y +T++D + D + + ++K + F KLQR I +C+ F S + + K IK + D N ++ + FE RIL + F I+++ L Q ++LT + +A + ++ ++ +E+ +H KS + ++ L+ + LI+D + +++ +S+I +A QK I ++ LI++ + + + L + + + P I +LK S R + K D + G+K +++S + +K ++ G F + ++I + +R I K+ L + + ++ +H FL N+ ++++ + L+E R +I L M T+D+ SKY + ++ E +G G+QG V+R + E A K+I+ L+ I+ EVY+S + EH NL+ ++ V ++ D R+ + IY LM D N M+++ L + Q+LKI LE+A AL+++H+ ++HRD+KLAN+L+ E V L+D+G KS N + VGT +++APE+VR Y D++S G+ LWYL +G + P + + +LL + RP RL N+ D LWDLM CW
Sbjct: 85 PCIIIVGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGITVAVQKDLTTIKKTVLGAEVFYLVTKMDVSKDTEQEANRPAQEIEEEKAERVFSKLQRLGYISPNETR-DKCNKFLCVSCWEVRRFRRKKELMIKKNKLDPEALKEMENSKWVRRFEEVKTRILKFAQDQFRNLIVSSGGGLRRIQSEILTLFMDKATNIKESNLRKKKALYQIKSLEQEIHQQSKSIVEKNRDELLRQAGLFFAERKPLILDEVRALKYSESVI----------SADMSQKDIEKKCVDEIHALINDRINCVILR-LPQRWGSEIVPTGIRRLKAES--------------RRVRKGCGTDARVPGVK-EDASRRLLVVVKGLLIGSF------ECYNIQDKAFRETDGTI-----SKENLVECLITSLKEWFEKQHREFLDNIASSEQLVESCMKLTEKERSEIKTLYPRVARLHMLTMDVISKYKYRGFRIDTEGNLGSGAQGEVFRVLNESGEPALAAKRIVSDEPSLDDIATEVYHSSVLEHDNLVHVVGVRLHKSKPDEKRWT---VEIYMELMCCDAWNLMQRHRLPVRQRLKIGLELAKALQFLHSSELIHRDVKLANVLVSEDLRQVKLSDFGLVKSTGFVNRTLVGTPIYLAPELVRGESYHTSADVFSLGIALWYLFEGTGKRHPEYVEIMPSVGAILL-AGALDCRPTRLPNMSDQLWDLMESCW 872
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1I8G8Z8 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 295.819 bits (756), Expect = 2.612e-82 Identity = 235/834 (28.18%), Postives = 404/834 (48.44%), Query Frame = 3
Query: 393 PTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVN-IHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLD-TDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSE-CHNFHGASLYSYMDYCNK----IKSQETD------FHNEQFCK-FESDLNRIL---LENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSI-----WNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKD-SVEKEM-IGQGSQGTVYRCVCNGKE--YAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVN----DNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQ-NNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEP-PLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
P I IVG K+GKS+ +N LL V Q+ CTAR+TR+TYS+ YV + + +QI + + L+ I + +V+L DEDR N + ++ + GIK +FL+ GID+IDSPGLNEN L+ L I+ LP++IYVID + + ++ ++K ++ + Y +T++D + D + + ++K + F KLQR I + N E C+ F S + + K IK + D N ++ + FE RIL + F I+++ L Q ++LT + +A + ++ ++ +E+ +H KS + ++ L+ + LI+D + +++ +S+I +A QK I ++ LI++ +II C RLCL+ ++D L K+ + + LK + + + ++S+ + +L K+ L + + ++ +H FL N+ ++++ + L+E R +I L M T+D+ SKY + ++ E +G G+QG V+R + E A K+I+ L+ I+ EVY+S + EH NL+ ++ V ++ D R+ + IY LM D N M+++ L + Q+LKI LE+A AL+++H+ ++HRD+KLAN+L+ E V L+D+G KS N + VGT +++APE+VR Y D++S G+ LWYL +G + P + + +LL + RP RL N+ D LWDLM CW
Sbjct: 85 PCIIIVGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGITVAVQKDLTTIKKTVLGAEVFYLVTKMDVSKDTEQEANRPAQEIEEEKAERVFSKLQRLGYI--SPNETKEKCNKFLCVSCWEVRRFRRKKELMIKKNKLDPEALKEMENSKWVRRFEEVKTRILKFAQDQFRNLIVSSGGGLRRIQSEILTLFMDKATNIKESNLRKKKALYQIKSLEQEIHQQSKSIVEKNRDELLRQAGLFFAERKPLILDEVRALKYSESVI----------SADMSQKDIEKKCVDEIHALIND--------------------RIIASF----CDFLKDGALRLCLQ-------EFDDLKQKVAEYEKDVEQTPAYQVLKKTLL---------EGYSLSSKDF-------LLGTISKENLVECLITSLKEWFEKQHREFLDNIASSEQLVESCMKLTEKERSEIKTLYPRVARLHMLTMDVISKYKYRGFRIDTEGNLGSGAQGEVFRVLNESGEPALAAKRIVSDEPSLDDIATEVYHSSVLEHDNLVHVVGVRLHKSKPDEKRWT---VEIYMELMCCDAWNLMQRHRLPVRQRLKIGLELAKALQFLHSSELIHRDVKLANVLVSEDLRQVKLSDFGLVKSTGFVNRTLVGTPIYLAPELVRGESYHTSADVFSLGIALWYLFEGTGKRHPEYVEIMPSVGAILL-AGALDCRPTRLPNMSDQLWDLMESCW 855
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:402922]) HSP 1 Score: 115.931 bits (289), Expect = 6.024e-26 Identity = 132/583 (22.64%), Postives = 248/583 (42.54%), Query Frame = 3
Query: 1140 LNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVD-FTNENLD----------EIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLM------KDSVEKEMIGQGSQGTVYRCVCNGKE--YAKKKIIVPTDL-LETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMK-KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
L+R+L+ F R++LT Q++ ++ + + +D F N+ D + R+ E L L + N + + + +++ L + +++ A++EF I+ P + T K K C + I +LI L+ + N ++++ LE C + + K S + S + L++ L Y ++ + + +W +K II L + T + W+ + + LAK+IC+ LN HD F +L + + + +E + ++ + + + L L+S+ L K + +E+ G+G G VY C G++ A K ++ P D ++ E +Y+ L +H L+ L +V D+ I++ + ++ + Y K L+L+++L+I+L+V ++++H Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ S RPERL + W LM CW+
Sbjct: 319 LHRLLVP-FARQVLTGQ------QVEAANRLNALHCRCLDLFINQAFDMQRDLQITPRRLEYTREKESELFASLMAIANRKQEEMKEMIVETLSTMKEQLLEDAANLEFTDIIVTPNGEPVTTKEIKSCIQQIQELIVVRLNQAVANKLISSVDYLRESFVGTLERCLSS------LEKSTTDSSVHNVTSNH---LKQILNAAYHVEVTFHSGSSVTRLVWEQIKQIIQRLTWVNPPAITPE-----WKRKVAQDAIESLSAAKLAKSICSQFRTRLNSSHDAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAPR----LARLSLESRSLRDVLLYGKPKLGREL-GRGQYGVVYLCDKWGEQNPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVNLHG-SVIDHTYGGGSSIAVLLIMERLHRDLYTGLKAGLSLKERLQIALDVVEGIRFLHGQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGS-----------------------------------------------RPERLPTFDEECWQLMEACWN 827
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:103046562]) HSP 1 Score: 96.2857 bits (238), Expect = 7.108e-20 Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 3
Query: 2097 EKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISL------EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSL--ALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVR---PERLGNIPDNLWDLMNECWD 2801
E + +G G+QG V+ +G+E A KK+ D+ ET E+ + +HPN++ V C + Y +M+ + + + +L +++ SL +A + Y+H I+HRDLK N+L+ + V ++D+G K L + SF GT +APE++R +K+DI+SFG++LW + G+ + + S+ ++ V N +++ PE + PD L+ +CW+
Sbjct: 153 ELQWVGSGAQGAVFLGKFHGEEVAVKKV---RDIKET---EIKHLRKLKHPNIITFKGV---------CTQAPCYCIIMEYCAQGQLYE-VLRAGRKITPSLLVDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELREKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWEMLTGEIP---YKDVDSSA--IIWGVGNNSLQLPLPE---SCPDGFKILLKQCWN 374
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:103046562]) HSP 1 Score: 96.2857 bits (238), Expect = 7.897e-20 Identity = 66/243 (27.16%), Postives = 122/243 (50.21%), Query Frame = 3
Query: 2097 EKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISL------EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSL--ALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
E + +G G+QG V+ +G+E A KK+ D+ ET E+ + +HPN++ V C + Y +M+ + + + +L +++ SL +A + Y+H I+HRDLK N+L+ + V ++D+G K L + SF GT +APE++R +K+DI+SFG++LW + G+ + + S+ ++ V N +++ + PD L+ +CW+
Sbjct: 153 ELQWVGSGAQGAVFLGKFHGEEVAVKKV---RDIKET---EIKHLRKLKHPNIITFKGV---------CTQAPCYCIIMEYCAQGQLYE-VLRAGRKITPSLLVDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELREKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWEMLTGEIP---YKDVDSSA--IIWGVGNNSLQLPLPESCPDGFKILLKQCWN 374
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000008518.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:14507502:14520436:1 gene:ENSAMXG00000008289.2 transcript:ENSAMXT00000008518.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.2781 bits (225), Expect = 4.945e-19 Identity = 53/134 (39.55%), Postives = 77/134 (57.46%), Query Frame = 3
Query: 2403 EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA---LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
E+ L+Y+H++ +HRD+K AN+LL EQ +V LAD+G L + +FVGT +APE+++QS YD K DI+S G+ LAKG EPP + + +KVL + KN P GN L + + C
Sbjct: 124 EILKGLEYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKG--EPP---HSELHPMKVLF-LIPKNNPPTLEGNYCKPLKEFVEAC 251
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322]) HSP 1 Score: 91.2781 bits (225), Expect = 5.754e-19 Identity = 50/134 (37.31%), Postives = 74/134 (55.22%), Query Frame = 3
Query: 2403 EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA---LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
E+ L Y+H++ +HRD+K AN+LL E V LAD+G L + +FVGT +APE+++QS YD K DI+S G+ LAKG EPP N ++VL + KN P G+ + + ++ C
Sbjct: 127 EILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKG--EPP---NSDMHPMRVLFHIP-KNTPPTLNGDFSKSFKEFVDSC 254
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 90.5077 bits (223), Expect = 1.438e-19 Identity = 61/245 (24.90%), Postives = 113/245 (46.12%), Query Frame = 3
Query: 2097 EKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLE--------VANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSL--ALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
E + +G G+QG V+ G+ A KK+ E ++ + + HPN++ V C Y +M+ + + + L +IS E +A + Y+H I+HRDLK N+L+ + V ++D+G K + + SF GT +APE++R +K+DI+SFG++LW L G+ + + S+ ++ V + ++ + P+ L+ +CW+
Sbjct: 16 ELQWLGSGAQGAVFLGKFRGEHVAVKKV------REQKETDIKHLHKLRHPNIITFKGV---------CTHAPCYCIIMEYCAQGQLYE---VLRAGRRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSKEMREKSTRMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP---YRDVDSSA--IIWGVGSNSLHLPIPASCPEGFKILLTQCWN 237
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209]) HSP 1 Score: 88.9669 bits (219), Expect = 3.850e-18 Identity = 62/204 (30.39%), Postives = 110/204 (53.92%), Query Frame = 3
Query: 2103 EMIGQGSQGTVY--RCVCNGKEYAKK---KIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLK-ISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNY---SFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFAN 2687
EMIG+GS G VY R G+ A K K+ L + E+ +HPN++ ++ D+ D E+ + T + +L ++ + E+Q++ I+ ++ +AL Y+H+ I+HRD+K NILL + V L D+GF ++++++ S GT ++++PE+V + YD D++S G +L+ L G PP + N
Sbjct: 8 EMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELRNLRREIDIMRGLQHPNIVQML-----DSFETD-KEVVVVTDYAEGELFQILEDDGNLPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGT--PPFYTN 203
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 86.2705 bits (212), Expect = 5.970e-18 Identity = 56/152 (36.84%), Postives = 81/152 (53.29%), Query Frame = 3
Query: 2355 MKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLK--LANILLDEQNNVYLADYGFCKSLA---LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
+K L Q I E+ L Y+H++ +HRD+K AN+LL EQ +V LAD+G L + +FVGT +APE+++QS YD K DI+S G+ LAKG EPP N + ++VL + KN P GN + ++ C
Sbjct: 113 IKPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKG--EPP---NSELHPMRVLF-LIPKNNPPTLEGNYSKAFKEFVDSC 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]) HSP 1 Score: 83.5741 bits (205), Expect = 7.317e-18 Identity = 59/190 (31.05%), Postives = 106/190 (55.79%), Query Frame = 3
Query: 2169 KKKIIVPTDLLE-TISEEVYYSYLFEHPNLLPLIAV-TVNDNIRFDCIEISIYTPLMKIDLENYMK-KNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNY---SFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLA------KGDCEPPLFANCQSTT 2702
KK +++ +D +E T+ E+ S + HP L L + +++ F + L DL +++ K +++ + E+ + L+++H+Q I++RDLKL NILLD+ +V +AD+G CK + + +F GT +IAPEIV KY+ +D +SFG+LL+ + +GD E LF + +++
Sbjct: 21 KKDVVIMSDDVECTLVEKRILSLAWGHPYLAHLYSTFQTKEHLMF------VMEYLNGGDLMFHIQVKGRFEIDRATFYAAEIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFESIRTSV 204
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: RPS6KA3 (ribosomal protein S6 kinase A3 [Source:HGNC Symbol;Acc:HGNC:10432]) HSP 1 Score: 83.1889 bits (204), Expect = 8.523e-18 Identity = 71/245 (28.98%), Postives = 114/245 (46.53%), Query Frame = 3
Query: 2100 KEMIGQGSQGTVYRCV--CNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKID--LENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANIL-LDEQNN---VYLADYGFCKSLALSNY-----SFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNEC 2795
+E IG GS RC+ EYA K II + + E+ Y +HPN++ L ++ D + + T LMK L+ +++ + + + +A ++Y+H+Q ++HRDLK +NIL +DE N + + D+GF K L N + FV APE++++ YD DI+S G+LL+ + G FAN T V+L GN WD ++E
Sbjct: 15 REDIGVGSYSVCKRCIHKTTNMEYAVKVIIDKSKRDPSEEIEILLRY-GQHPNVITL------KDVYDDGKSVYLVTELMKGGELLDKILRQKFFSEREASAVLQTIARTVEYLHSQGVVHRDLKPSNILYVDESGNPESLRICDFGFAKQLRAENGLLMTPCYTANFV--APEVLKRQGYDAACDIWSLGVLLYTMLAGHTP---FANGPDDTPGVILTRIGSGRFLLSGGN-----WDTVSEA 242
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 90.8929 bits (224), Expect = 9.665e-20 Identity = 77/274 (28.10%), Postives = 130/274 (47.45%), Query Frame = 3
Query: 2070 SKYLMKDSVEKEMIGQGSQGTVY--RCVCNGKEYA----KKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRF---DCIEISIYTPLMKIDLENYMKKNILTLEQQLKI-SLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVR---------------------PERLGNIPDNLWDLMNECW 2798
KY ++D +G GS G V+ R NG+ YA KK+I+V +E ++E + HP ++ + + F D IE +L + ++K+ K + EV AL+Y+H+++I++RDLK NILLD+ ++ + D+GF K + Y+ GT +IAPE+V Y++ ID +SFG+L++ + G P + S T+K ++ N +R +RLGN+ + D+ N W
Sbjct: 80 GKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGG--------ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYT--PFY---DSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPW 340
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 90.5077 bits (223), Expect = 1.160e-19 Identity = 81/297 (27.27%), Postives = 136/297 (45.79%), Query Frame = 3
Query: 2010 KISNETSSFTLLLMRTL----DLQSKYLMKDSVEKEMIGQGSQGTVY--RCVCNGKEYA----KKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRF---DCIEISIYTPLMKIDLENYMKKNILTLEQQLKI-SLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE--------------------PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
K+ E S+ L+ + + D KY + D +G GS G V+ R NG+ YA KK IV +E ++E + HP ++ + + F D IE +L + ++K+ K + EV AL+Y+H+++I++RDLK NILLD+ ++ + D+GF K + Y+ GT +IAPE+V Y++ +D +SFG+L++ + G PP F +K L+ +++ ERLGN+ + D+ N W
Sbjct: 57 KLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGG--------ELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLI---TRDLS-ERLGNLQNGSEDVKNHPW 341
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 88.9669 bits (219), Expect = 3.140e-19 Identity = 69/236 (29.24%), Postives = 116/236 (49.15%), Query Frame = 3
Query: 2043 LLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVY--RCVCNGKEYA----KKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAV---TVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKI-SLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLE 2720
L ++L + KY + D +G GS G V+ R V NG+ YA KK+ +V +E ++E L EHP L+ + N + D IE +L + ++K+ K + EV AL+Y+H NI++RDLK NILLD ++ + D+GF K + ++ GT +IAPE++ Y++ +D +S G+L++ + G P + T + +L+
Sbjct: 54 LPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGG--------ELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYT--PFYDTTPMKTYEKILQ 279
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]) HSP 1 Score: 83.9593 bits (206), Expect = 6.162e-17 Identity = 42/105 (40.00%), Postives = 65/105 (61.90%), Query Frame = 3
Query: 2370 LTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA---LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPP 2675
LT Q I E LK++H+++I+HRD+K N+LLD + V + D+GFC L + VGT +APE+V+Q +YD+KID++S G++ + +G EPP
Sbjct: 665 LTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEG--EPP 767
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473]) HSP 1 Score: 82.8037 bits (203), Expect = 1.020e-16 Identity = 43/101 (42.57%), Postives = 61/101 (60.40%), Query Frame = 3
Query: 2382 QQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA---LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPP 2675
Q I E LK++HN+ I+HRD+K NILL+ Q V + D+GFC L + VGT +APEIV Q YD+K+D++S G++L + +G EPP
Sbjct: 483 QMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEG--EPP 581
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO44458 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVW1]) HSP 1 Score: 163.31 bits (412), Expect = 3.426e-41 Identity = 165/778 (21.21%), Postives = 324/778 (41.65%), Query Frame = 3
Query: 594 IPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLD----TDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFE---------REILT-----ATKSLIDFQMDVLTKIISRA----------KQFVDFTNENLDEIF-TMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRC-VCNGKEYAKKKIIVPTD--LLETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPL-FANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
+P+ +ELNDE++++P + + + + LK+G L+ SP E N+ S VLP+++Y I+ Q + D + +L +K P+L I + T+ ++E +++ I+ + F +L++ + + + ++ + D N + +L+ENF R++L A + D L+ I+ A + +++ E +E+F + + R ++K I ++ ++N S I+ + +EF E K K+ C I +L+ ++ + ++++ L+ C ++ K+ + + +C ++ + + L+ + Y+ ++ + + +W +K I L T W+ + +L + LAK+IC L H+ F + + +E R K+ + L + + L+ L +G+G G VY C G+ K +VP D ++ E +Y+ L H ++ +I ++ + + + ++ DL +K L+ ++ ++++V ++++H+Q ++HRD+KL N+LLD +N + D GFCK A+ + S VGT +H+APE+ YD +D+Y+ G+LLWY+ G PL F C S L + VRPERL N + W LM CW
Sbjct: 138 VPRGDLELNDEEKADPAMASAVAEISLNHALLKAGAQLVCSPSNPEGDAENIF-SACCEDVLPILVYSIE-QDFLSDKDEAELLQIKALAPDLPIFFVKCSRKKPDLTNSMTEYAQHEAIEEFAEARTRIFEQLRKIGYLTQESPEQKK-----------------ALQHEVLDIRNAKAILDSVIPKSMLIENFSLFPCFLLFVRQVLQFHLVEAATVMNDAHCRALSLFITTAFDMARDMIITPRRLEYAKEKEEELFLALMETATRKQEEIKEVIKST-----------IENLSPQILKEVESLEFRGVECSGEQKLLNPKDLDHCTFQIQELVLGRINKAVAGNMISSVEYLRESFVGTLQRCIDS--LEKMDSDSRRNACEYTSAT---VALKHVIDAAYQVEVTYRASSSLARLLWEKMKQAI-----QTLPGKTPPKVDSAWKRKVAQDMLTSLSETRLAKHICLQFRTRLIKSHESFTSCMRMLEANHTGRLEKTEEQRMKVRKSHAPKIARLALESWSLRDVVLYGMPQLSREVGRGQYGVVYACDRWAGRHPCAIKSVVPPDDKHWNDLALEFFYTRSLPLHDRVVSIIGSVIDYSYGGGSSPAVLLVMDRLQRDLYQGIKAG-LSFRARMHVAVDVVEGIRFLHSQGLVHRDIKLKNVLLDSKNRGKITDLGFCKPEAMMSGSIVGTPIHMAPELF-SGHYDNSVDVYALGILLWYICAGTVRLPLAFEQCASK--DHLWNAVRRGVRPERLANFDEECWMLMEACW 871
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG13]) HSP 1 Score: 130.954 bits (328), Expect = 1.683e-34 Identity = 64/185 (34.59%), Postives = 113/185 (61.08%), Query Frame = 3
Query: 2244 HPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECW 2798
HPN+LPL+ + + + I++ I + M DL + + + +L ++L+I L+VA ALKY+H+ +++HRD+KL N+L+DE++ L D+G CK+ + S VGT +APE+V+Q+ Y++ +D+Y+FG+L+W + +G P + +L+ ++ +PERL W+LM CW
Sbjct: 11 HPNILPLVCTVIQPGL-CNSIKVLIVSERMASDLHRALPR-LTSLRKRLEILLDVARALKYLHSLDLIHRDVKLQNVLVDEKSQGSLTDFGLCKAEGVMENSLVGTPTSMAPEMVKQN-YNKSVDVYAFGILMWRVCEGQGNQPRNIALHPIPIIMLVRNALEDRKPERLDRFMGPCWNLMERCW 192
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49816 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG14]) HSP 1 Score: 125.176 bits (313), Expect = 1.803e-29 Identity = 166/674 (24.63%), Postives = 290/674 (43.03%), Query Frame = 3
Query: 111 NLRQTIQLYQNDLKNVLVIQENTKKAFQHITDIL-DPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHK------ENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIK-SQETDFHNEQFCKFESDLNRI--LLENFEREILTATKSLIDFQMDVLTKIISRAKQF----VDFTNENLDEIFTM----RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIAD-MEFPKS-------IIIPENK-AFTKKNAKFCQKHIIDLICKDLDNLIDNFV------QDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGL---------FRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIR 2006
+L + + ++ + ++ I E+T K FQ I L D E L++ + L + V G+ L +I+L + L E S T E K + P + + G GKS+++N L VV + CTAR+ R+TYSE YV LV +ER++LK+ IP+ +ELN +DR + VN + G+ FLK+GID+IDSPG +EN VL+ L+ N + +LP +IYV+DG N+LS S P D D+ + + + ++ +K + + KL + I NFHG S + ++ ++K + D F ++ +R+ L +F + LTA ++ + LT ++SR F +F + E M R+ E +H ++ +I + L I ++ SD I+++ ++ +E ++ +IP N K C+ I +++ + I + + +DE LEN I K++ + +S + + L Y ++ S+F W K IIT L F D+ + W+ Q + + D L +++ +L + H F L+K V ++ L ++ R
Sbjct: 3 SLEEVFKEFRRNRSSLQQIHEDTLKCFQSIEKSLADKKHEELVQEMTT-TLASQQQVDGSDINLENIQLVTGGESIATNLSE-SLYTEAERSKVSKFLTQTPALIVTGQTNCGKSSIINEFLGARVVPTKAQPCTARIVRMTYSETPYVRLVKRDGTELERRELKSNKIPREFIELNIDDRDDEKRVNATVEAGLCVDFLKAGIDVIDSPGTSENDVLDELVRNQMKSILPFVIYVVDGH---------NLLS---SSPAKTDSSDEESDDDDNDESVKQAEPVQESKKRK--VYDKLVKKGFIIPCEGGRDAHPNFHGLSAWRIGEFNKRMKMNPAWDDSEGLFKEYMDAFHRLHTCLHDFTKSSLTAC---VENTCNTLTSVLSRCLSFFIKKANFLKQGKKETMVMINRIRQEELTVHENILRQIEKQR-LDITEVV------SDGILEIKSNVLEEARTFQYSELDFVIPANGWVHGAKAVTECRDQIWEMVFNKVRQRISSTLMAMFSHRDEFLVELEN---------RIKKIEQEAFPDGRRSTAGVTIHLMLVNCY-------EVSRSNFRFWA-TKTIITRLVDFLKRLFKFPLDVIRGKVKVGDMEWKERQASVAIEAIDVAKLVEHLMQKLLERFDECHSIFNDELDKVMAVFKQGQTLKDSQR 633
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGQ2]) HSP 1 Score: 122.865 bits (307), Expect = 1.635e-28 Identity = 193/848 (22.76%), Postives = 366/848 (43.16%), Query Frame = 3
Query: 348 VENSFRTNNEIHK------ENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKK-LKNKPIPKYIVELNDED-RSNPDEVNKLIRVGIKSKFLKSG-IDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSE--------LIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKI--------ISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSII---IPENKAFTKKNAKFCQKHIIDLICKDLDNL-------IDNFVQDELNKNLENCFE-AHLSPKIINKL---KLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMN---LEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQ-GSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIA----PEIVRQSKYDQKI--DIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRP 2744
V N+F + E K + I +VG +GKS+L+N LL + A CT+R+ RI YS+ NYVE+ + + ++ K+ K IP+ + L+D+ RS+ + V +++VG+ + L+ G ++L+D+PG++EN VL+ ++ I+ +L V+IYVIDG +S++ D + SLK I ++ I + ++DT+ + ++ + + K+ ++ L LI +C FHG S + K++ HN QF +D ++ +F + + + + + D+L +I ISR D + D I ++ VE N + + ++ L + + +++ S+ I+ +MEF I + N+ + C+ I L+ + N+ + ++ + L+ C E A + NKL +L+ C L+ + + N+ + L+ + +F W+ LK T + LSN T ++ W+ K IL+ + ++ I +L D H+ F +N +E+ K+ K+ + + + + SF ++ RT L + L + E +G+ G +GTVY C+ + K ++ + Y S + PN + + FD D ++ + + L +++ A Y +N+ D +L N+ LD L D + ++ + F H++ P I + Q D+Y+ G+L W LA P +A Q+ VK + E T++ P
Sbjct: 72 VINAFISEQETQKFEEFVSKKAAILVVGQTNSGKSSLINELLGGTYLPTAEIPCTSRIVRICYSDNNYVEVQGPNGECVQGKQSFGKKRIPRDEIALDDDKKRSDAEWVRCVVKVGLNNSLLRGGHLELVDAPGMSENEVLDQIVQECIHGILQVVIYVIDGNSSLRTQDREFLFSLKERIDSIPIFFVCNKVDTNAKAAEFDRDSDDSDDDSSLDNVETKMRQAYKALVGYGLIDSDI-QLEDCAAFHGISTHEVR------KARHKKIHN-QF----TDAFEVMKSSFLTFLDNSLNANLGYTTDLLLRILQRIFDFYISRGPLRGDLESICRD-IRGIQAVERTYFNKMCEYVKSNHTKLHNVMESSVNSSSENILKEAEEMEFAPIRIGNAVKRNEIINQ-----CRDQIHKLVLLRVLNISLKEATKTLRVIAGQMKRKLDICLENAAKHDNLTNKLVTNQLHICYLNRRDIEEMI---NMGPIVNFSLM-----SRTFKTWDQLKRFATDV----LSNVTGTEVNKSWKRKIAKNILDNVNFSEVSHRIIEVILTDNQASHETFQINTRCMEQLCKMADKQSDCQQMV---VFEHAHSFAEVICRTEALMNTLLHPEVKLLEPLGRPGYRGTVYNCLVPAGRFGKCDVVA----------KQYKSVV--SPNQFLALQQCMRS---FD-----------DADQHGILRPSSIVL-------VDITEACLYCRAKNVHLIDPRLTNVKLDGDYRSML-DISKPRDDSVPYPDGMAPF-HVSAPPPPLIAFSTNTTQTAHHDVYALGILGWLLAMEKYIRPQYA--QTVDVKEIYEATSRMAHP 849
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO33902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQU9]) HSP 1 Score: 97.4413 bits (241), Expect = 5.043e-21 Identity = 44/107 (41.12%), Postives = 76/107 (71.03%), Query Frame = 3
Query: 489 CTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINK-VLPVMIYVIDG 806
CT+R+ RI+YSE N+V+LV+ +I+R+K K K +PK L+D + + D ++ ++ VG++ +FL+SGI+LIDSPG E+ L+ L+ + K ++P+++YV+DG
Sbjct: 66 CTSRIVRISYSESNFVQLVDEAGNVIQREKFKRK-VPKKYAVLSDAAKESADNLSAIVEVGVEHEFLQSGIELIDSPGRCESDALDRLVDGFLEKGIVPLIVYVVDG 171
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:100144388]) HSP 1 Score: 164.851 bits (416), Expect = 2.758e-41 Identity = 133/516 (25.78%), Postives = 236/516 (45.74%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEY--AKKKIIVPTDL-LETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCE-PPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L + L + N + + + +++ L + + +++ A++EF I+ P + T K K C I +LI L+ + N ++++ LE C + + K L S + S + L++ L Y ++ + + +W +K II R N + W+ + + LA++IC+ LN H+ F +L + + + +E + ++ + L + + L+ L +G+G G VY C G Y A K ++ P D ++ E +Y+ L +H L+ L ++ + I + + + DL +K L+L ++L+I+L+V ++++H Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ KYD +D+Y+FG+L WYL G + P F C S L K RPERL + + W LM CW+
Sbjct: 375 REKEGELFSSLMAIANRKQEEMKEMIVETLGSMKEQLLEDAANLEFTDVIVTPNGEPVTSKEIKSCIHLIQELIVVRLNQAVANKLISSVDYLRESFVGTLERCLSS------LEKSTLDSSVHNVTSNH---LKQLLNAAYHVEVTFHSGSSVTRFVWEQIKQII---HRITFVNPP--AITPEWKRKVAQDAIESLSAAKLARSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDVLLHGKPRLGRELGRGQYGVVYLCESWGGHYPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVDLHGSVIDHSYGGGSSIAVLLIMERLHRDLYTGLKAG-LSLRERLQIALDVVEGIRFLHGQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-TGKYDNSVDVYAFGILFWYLCTGSVKLPEAFEKCSSK--DQLWNNVKKGARPERLPSFDEECWQLMEACWN 872
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:100144388]) HSP 1 Score: 116.316 bits (290), Expect = 4.689e-26 Identity = 114/515 (22.14%), Postives = 214/515 (41.55%), Query Frame = 3
Query: 1296 RKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDN-------FVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEY--AKKKIIVPTDL-LETISEEVYYSY-LFEHPNLLPLIAVTVNDNIRFDC-IEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
R+ E L + L + N + + + +++ L + + +++ A++EF I+ P + T K K C I +LI L+ + N ++++ LE C + + K L S + S + L++ L Y ++ + + +W +K II + + T + W+ + + LA++IC+ LN H+ F +L + + + +E + ++ + L + + L+ L +G+G G VY C G Y A K ++ P D ++ E +Y+ L +H L+ L ++ + I + + + DL +K L+L ++L+I+L+V ++++H Q ++HRD+KL N+LLD+QN + D GFCK A+ + S VGT +H+APE+ RPERL + + W LM CW+
Sbjct: 407 REKEGELFSSLMAIANRKQEEMKEMIVETLGSMKEQLLEDAANLEFTDVIVTPNGEPVTSKEIKSCIHLIQELIVVRLNQAVANKLISSVDYLRESFVGTLERCLSS------LEKSTLDSSVHNVTSNH---LKQLLNAAYHVEVTFHSGSSVTRFVWEQIKQIIHRITFVNPPAITPE-----WKRKVAQDAIESLSAAKLARSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDVLLHGKPRLGRELGRGQYGVVYLCESWGGHYPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERLVDLHGSVIDHSYGGGSSIAVLLIMERLHRDLYTGLKAG-LSLRERLQIALDVVEGIRFLHGQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELF-----------------------------------------------TGARPERLPSFDEECWQLMEACWN 859
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:101162759]) HSP 1 Score: 97.8265 bits (242), Expect = 2.834e-20 Identity = 68/244 (27.87%), Postives = 124/244 (50.82%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISL------EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVR---PERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ D+ ET E+ + +HPN++ V C + Y LM+ + + + +L +++ SL +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW + G+ + + S+ ++ V N +++ PE + PD L+ +CW+
Sbjct: 167 QWVGSGAQGAVFLGKFHGEEVAVKKV---RDIKET---EIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEYCAQGQLYE-VLRAGRKITPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWEMLTGEIP---YKDVDSSA--IIWGVGNNSLQLPIPE---SCPDGFKILLRQCWN 386
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:101162759]) HSP 1 Score: 97.4413 bits (241), Expect = 3.811e-20 Identity = 68/244 (27.87%), Postives = 124/244 (50.82%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISL------EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVR---PERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ D+ ET E+ + +HPN++ V C + Y LM+ + + + +L +++ SL +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW + G+ + + S+ ++ V N +++ PE + PD L+ +CW+
Sbjct: 167 QWVGSGAQGAVFLGKFHGEEVAVKKV---RDIKET---EIKHLRKLKHPNIITFKGV---------CTQAPCYCILMEYCAQGQLYE-VLRAGRKITPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWEMLTGEIP---YKDVDSSA--IIWGVGNNSLQLPIPE---SCPDGFKILLRQCWN 386
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:101160549]) HSP 1 Score: 95.1301 bits (235), Expect = 1.741e-19 Identity = 62/241 (25.73%), Postives = 123/241 (51.04%), Query Frame = 3
Query: 2103 EMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISL------EVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLA--LSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+ +G G+QG V+ +G+E A KK+ ++ ET ++ + +HPN++ + C + Y +M+ + + + +L +++ SL +A + Y+H I+HRDLK N+L+ + V ++D+G K L+ + SF GT +APE++R +K+DI+SFG++LW + G+ + + S+ ++ V N +++ + PD+ L+ +CW+
Sbjct: 160 QWVGSGAQGAVFLGKLHGQEVAVKKV---RNIKET---DIKHLRKLKHPNIITFKGI---------CTQAPCYCIIMEYCAQGQLYE-VLRAGRKITPSLLMDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWEMLTGEVP---YKDVDSSA--IIWGVGNNSLQLPVPDSCPDSFKLLLRQCWN 379
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056716.1 (SMESG000056716.1) HSP 1 Score: 1814.66 bits (4699), Expect = 0.000e+0 Identity = 929/933 (99.57%), Postives = 929/933 (99.57%), Query Frame = 3
Query: 84 MMNIESFHENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWDQXXXXXXXXXXXXXXXQDLLSEIFEKK 2882
MMNIESFHENLRQTIQLYQNDLKNVLVIQENTK AFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRIL ENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKN ENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERL NIPDNLWDLMNECWDQNPSNRPNINSIISTIQDLLSEIFEKK
Sbjct: 1 MMNIESFHENLRQTIQLYQNDLKNVLVIQENTKTAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILSENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNFENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLENIPDNLWDLMNECWDQNPSNRPNINSIISTIQDLLSEIFEKK 933
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056716.1 (SMESG000056716.1) HSP 1 Score: 1813.12 bits (4695), Expect = 0.000e+0 Identity = 928/932 (99.57%), Postives = 928/932 (99.57%), Query Frame = 3
Query: 87 MNIESFHENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWDQXXXXXXXXXXXXXXXQDLLSEIFEKK 2882
MNIESFHENLRQTIQLYQNDLKNVLVIQENTK AFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRIL ENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKN ENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERL NIPDNLWDLMNECWDQNPSNRPNINSIISTIQDLLSEIFEKK
Sbjct: 1 MNIESFHENLRQTIQLYQNDLKNVLVIQENTKTAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILSENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNFENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLENIPDNLWDLMNECWDQNPSNRPNINSIISTIQDLLSEIFEKK 932
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056697.1 (SMESG000056697.1) HSP 1 Score: 865.144 bits (2234), Expect = 0.000e+0 Identity = 444/909 (48.84%), Postives = 626/909 (68.87%), Query Frame = 3
Query: 105 HENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENK-AFTKKNAKFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSF---------SIWNFLKNIITGLFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWD 2801
+NL Q I Y+ + + +L IQ +TK+AF IT+IL P + LLEC+N+DN+ +I + G + E+ ISA + + + N ++ NP IAIVG VKAGKST VN+LLRKNVV QA++ CTARLTR+TYS +NYVE+++ + +++ERKKL IPK ++LNDEDR+ E+NK++R GIKS+FL+ GID+IDSPGL+EN L L N+I +LP+MIYVIDG+TSVKQTDI+++L LK ++P L IIYFI++LDTDD +E +D IK A+ K++ F+KLQ +N IP +F H+SEC FHGASLY YMDY +++E FH + F KFE L L+ NF+ +I A S+++FQMDVLTKII+RA+ DFT ENL+ IFT+RK+EE L +K I++SK LI RL++RL++ES+ II+ I D+E+P SI +PEN K+ + CQ I+ +C+ L+N+I FV+ EL + + E ++ ++ +++ ++ + K+PYR+ LER L YK++ L + N+ I N +K + LF +D ++ D+ S W+ Q K L CD LA+ +C +++ D KH+ FL+ LE E + + K+I++SE IR +++ + F LLM TLD++ +Y+++ V E IGQG+QG VYRC CNG+E AKK + +P + L I+EEVYYSYLF+HP LLPLIAV++ D+ D +ISI+ PLMK D+ Y+K+N ++++++LKI+L+VA AL+Y+H Q IMHRDLKLANILLD+ NNV+LADYGFCKS+ALSN+SFVGT VHIAPEIVR++ YD K+DIYS+GMLLWYLA+G P FA QS +VL T N+RPERL I D LW+LM CWD
Sbjct: 10 RQNLNQAIHEYRENRERLLRIQSSTKEAFSQITEILKPTTAELLECVNIDNIAHIASDLGVINKPTE-EIEISAEEFLNKTIYEKQDVNQKVDIGNPAIAIVGQVKAGKSTFVNVLLRKNVVCQAYERCTARLTRLTYSSQNYVEILDENGKVLERKKLNKPTIPKKYLQLNDEDRTKRSEINKIVRAGIKSQFLEYGIDIIDSPGLSENATLTNLSKNMIKSILPIMIYVIDGRTSVKQTDIADLLELKNAVPKLQIIYFISKLDTDDTTETEFSDPIKLAESKMELAFKKLQYNNFIPTSFKHWSECPYFHGASLYCYMDYYKNKRTEEILFHFDLFGKFEVALQSFLMINFKNKIFEACDSMLNFQMDVLTKIITRARVLSDFTKENLNHIFTIRKIEEELFEKIKGVISSSKNDLIKRLIERLEDESEAIINPIGDLEYPNSISVPENGMVIDKRLIEQCQGVIMSSLCQGLENVIKQFVESELYQKYRDAIEVQVTSRMKDEIGVHEAKCLGKTPYRMSLERILASNYKFNSLT-ALSNTEGHNVIMKLMQEILNSIKLFFSKLFGTDQIKESVDVKSHEWKTQQAKECLKRCDHSTLAEEVCKSLIDDFENKHNAFLLALENENRFVHKKISVSEEIRTQMAEKAPDFAGLLMLTLDVKGRYMLQGIVVNEKIGQGAQGEVYRCSCNGQEMAKKTVNLPMNQLNDIAEEVYYSYLFQHPRLLPLIAVSITDSTELDSKQISIFAPLMKTDVSKYLKRNKVSIKERLKIALQVAEALQYLHRQQIMHRDLKLANILLDDNNNVFLADYGFCKSMALSNHSFVGTPVHIAPEIVRKAIYDFKVDIYSYGMLLWYLAEGTGRHPRFARVQSNIAQVLWASTEHNMRPERLDEISDELWELMQACWD 916
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056718.1 (SMESG000056718.1) HSP 1 Score: 713.761 bits (1841), Expect = 0.000e+0 Identity = 413/928 (44.50%), Postives = 583/928 (62.82%), Query Frame = 3
Query: 96 ESFHENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLLECINLDNLLNIF---------NVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSEL------IENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNA-KFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDL-LGLKIKNSSFSIWNFLKNIITG-------LFRSDLSNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKI-SNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVTNKNVRPERLGNIPDNLWDLMNECWDQ 2804
E F + Q Q Y+ + K ++ IQ T+ AF ++TDIL P + LLECIN+++L F NV N + + D+E +S NP IAIVG VKA KST++N+LLRK VV QA CTAR+TR+TYSEENYVEL + +++RK L+ IP V LN+ DRSN E+ K ++ GI KFL SGIDLID+PGLNE+ +L+ L + +LP+MIYVIDG TSVKQTD+S++L LK +IP+L IIYFI++LD+D +E IE I+ + +KL F++LQ N IPKT+NH+SEC FHGASLY MDY N +S E F+ E F +FE++L+ LL +FE I TA SLI F MDVL KIISR + D + EN ++I ++++EE L ++K+ +++ K L + L+K+ ESD I L+ D E+P SI +P++ N + CQK I+ +IC L+ LI+ FV+DEL + E H + + KL + + S ++PY +CL + LT+ YK + + K S+ + NI++ +F + D+ S+ W+ Q K L CD LA N+C N++ +L H+ F + LE E K QK I +S+ I+ + N F++LLM TLD++ +Y+MKD E IGQGSQ +VYRC NGKE A K V D L IS+EVYYSYLFEH +LLP IA+++ ++++ ++SI+TPLMK D +++ +N ++L ++L I+L+ A AL+Y+HNQ+IMHRDLKLANILLD ++NVYLADYG CKS A++N + VGT +H+APE++ Q+ YD KIDIYSFG+LLWYL +G P + S +VL +K+VRPERL N+PD LWDLM+ CWD+
Sbjct: 9 EQFCFKINQASQEYRENRKALIDIQTRTRTAFLNLTDILKPSTAELLECININDLSEAFAEFTLVQNENV-PNDKYVPDVEKNVSC---------------------NPAIAIVGQVKAAKSTMINVLLRKTVVCQAFSRCTARITRLTYSEENYVELFDSDGTLLKRKLLRAPKIPARFVRLNENDRSNIKEIRKEVKAGINCKFLMSGIDLIDTPGLNEHSLLSNLSKETVKNILPIMIYVIDGNTSVKQTDLSDLLELKNAIPDLKIIYFISKLDSDISTEQLSDPEEIEKMKIELSIEKLSIAFKRLQNQNFIPKTYNHWSECPYFHGASLYKIMDYFNHQQSPEILFNLELFNRFENELSLFLLVHFENIITTAAYSLIYFHMDVLAKIISRGIKIKDSSEENQNQIERIKRIEEELFENIKNVLSSQKLYLKEILIKKFKTESDSIYKLVQDCEYPSSIRVPDSGITIDNNTIRLCQKFIVSIICFGLEQLIERFVEDELFSKYRSKVENHFNDNMDKKLYGKNSKFSGRNPYDMCLRKILTENYKCNFKVNPKNLEDMSSMRKLINNILSSIKIFLWKIFEVNSLKGCKDVKSQKWKHNQVKYCLLNCDFSKLADNVCINLIENLQNCHEAFNLALEIERKHFQKSIQISDNIKQSLKKNHWPVFSVLLMETLDIKGRYMMKDVKRHEEIGQGSQASVYRCTVNGKELAMKTRYVKADKLSEISDEVYYSYLFEHRHLLPFIAISI--KLQYNSAQVSIFTPLMKSDALDFIIQNEVSLVKRLMIALQTAEALQYLHNQSIMHRDLKLANILLDNEDNVYLADYGCCKSTAIANNTIVGTPIHMAPEVI-QNSYDDKIDIYSFGILLWYLVEGKGNHPKHLSVHSEVFRVLYLAAHKDVRPERLENMPDELWDLMSACWDK 911
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056719.1 (SMESG000056719.1) HSP 1 Score: 705.671 bits (1820), Expect = 0.000e+0 Identity = 392/844 (46.45%), Postives = 561/844 (66.47%), Query Frame = 3
Query: 108 ENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLLECINLDNLLNIFNVCGNTETLNDIELAISALRYDSGLVENSFRTNNEIHKENPTIAIVGSVKAGKSTXXXXXXXXXXXXQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKNKPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILLENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNA-KFCQKHIIDLICKDLDNLIDNFVQDELNKNLENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKY----DLLGLKIKNSSFSIWNFLKNIITGLFRSDL----SNDTFDINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQK 2612
ENL + I+ Y+ + + ++ IQ +TKK F IT+IL + +LL+C++ +NL NI GN E +DI L + +++ F EI NP IA+VG VK+GKST VN LLRKNVV QA + CTAR+TR+TYS +N+VE+++ I++RK L IPK ++L + R + +E+NK I+ GI S FLK GID+IDSPGL+EN LN L N+I +LPVMIYVIDG+TSVKQTDIS++L LK ++PNL IIYF+++LDTDD+SE D IK A+ K+D F+KLQ +N IP TF+H+SEC+ FHG SLY++MDY ++ ET FH FCKFE +L+ LL+NF +I LIDFQM+V+TKII+RA+ DF N DEI ++++EE+L+ +KS + +SK L L+KRL NESD+I+ I+++ +P + IP + ++K K CQ II +C+ L+N+I FV++EL + +A + ++ NK+ S S K+ Y LCL+R + + YK+ +L L N+ N +++ I G + L S + D+ W++ Q K L CD +LA +C N+L + KH+ FL ++ E +QK+I LS+ IR K++ + F LLM +LD++ KY +++ EKE IG GSQGT++RC+C+GKE AKKK IV D +E I+EE+YYSY FEHP+LLP +AV + D D E++IY+PLMK DL NY+ N L ++ I++++A AL+Y+H+ NIMHRDLKLANILL+E N+V+LADYGFCKS AL++YSFVGT +HIAPEI+ ++ YD K
Sbjct: 13 ENLTRVIKDYRQNRERLVKIQSSTKKTFDQITEILKSDTGSLLDCVDSNNLNNIAADLGNFED-SDI------LADEQFYLKSVFEKQVEIG--NPAIAVVGQVKSGKSTFVNTLLRKNVVPQAFERCTARITRVTYSMKNFVEIISNEGVILKRKSLNTTTIPKRFLQLKENVRIDEEEINKQIKAGIHSNFLKCGIDIIDSPGLSENETLNNLSKNMIKSILPVMIYVIDGRTSVKQTDISDLLELKNAVPNLQIIYFVSKLDTDDLSETENADPIKLAELKMDIAFKKLQFNNFIPLTFSHWSECNYFHGCSLYAFMDYTQNSRTPETLFHYNLFCKFEENLHHYLLQNFRNKIEEVCNFLIDFQMEVMTKIINRAQMLSDFNRINFDEINRIKRIEEKLYKKIKSAVKDSKIHLKSCLIKRLKNESDVIVKPISEIIYPNHLNIPLDGIVSEKQQIKQCQSIIISNVCQGLENVIKRFVEEELFQKYLEAIQAQIPFRMKNKI---SVTKSGKTNYGLCLDRRMAEIYKFNISNNLSNLDGNNTIMKFMNVIRSSIKGFLMTGLKIEFSQKSVDVKDPKWKMKQAKKCLERCDFKILADEVCKNLLEEFYKKHNEFLAVMDLENFYVQKKIELSDEIRQKLAEKAPIFAELLMLSLDVKGKYFLQNVEEKEEIGSGSQGTIHRCICDGKELAKKKYIVNIDSIEEIAEEIYYSYSFEHPHLLPFLAVAIIDTEEIDSKEVAIYSPLMKTDLYNYLCHNKTKLSHRISIAIQIAEALQYLHSHNIMHRDLKLANILLNEDNSVFLADYGFCKSTALTHYSFVGTPLHIAPEIIMKNNYDYK 844 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032861 ID=SMED30032861|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2926bpback to top protein sequence of SMED30032861-orf-1 >SMED30032861-orf-1 ID=SMED30032861-orf-1|Name=SMED30032861-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=934bp MMNIESFHENLRQTIQLYQNDLKNVLVIQENTKKAFQHITDILDPISENLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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