SMED30032809

Overview
NameSMED30032809
Smed IDSMED30032809
Length (bp)805
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30032809 (SMED30032809) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30032809 (SMED30032809) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30032809 (SMED30032809) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30032809 (SMED30032809) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032809

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30032809h1SMcG0003494 dd_Smed_v4_2522_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30032809h1SMcG0003494 dd_Smed_v6_2522_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30032809 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.022581:469..1315 -4003
v31.004521:17262..18108 -3976
Homology
[Close]
BLAST of SMED30032809 vs. Ensembl Human
Match: QPRT (quinolinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:9755])

HSP 1 Score: 198.749 bits (504), Expect = 4.271e-62
Identity = 93/219 (42.47%), Postives = 137/219 (62.56%), Query Frame = -3 
Query:  114 FSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 767
             +L++ PV L   V+ W+ ED P  + + +V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L   + +  ++GPA+ +L+ ER ALN L R  G+A+ A       +   W G + G+RKTTPGFR+VEKY + +GG ++HRYDL  +VMVKDNH+ A G +EK+V   R      +KVEVEC +L EA++A ++GAD+V+LDNF
Sbjct:    6 LALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNF 224
[Close]
BLAST of SMED30032809 vs. Ensembl Human
Match: QPRT (quinolinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:9755])

HSP 1 Score: 198.749 bits (504), Expect = 4.271e-62
Identity = 93/219 (42.47%), Postives = 137/219 (62.56%), Query Frame = -3 
Query:  114 FSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 767
             +L++ PV L   V+ W+ ED P  + + +V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L   + +  ++GPA+ +L+ ER ALN L R  G+A+ A       +   W G + G+RKTTPGFR+VEKY + +GG ++HRYDL  +VMVKDNH+ A G +EK+V   R      +KVEVEC +L EA++A ++GAD+V+LDNF
Sbjct:    6 LALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNF 224
[Close]
BLAST of SMED30032809 vs. Ensembl Xenopus
Match: QPRT (quinolinate phosphoribosyltransferase [Source:NCBI gene;Acc:100495332])

HSP 1 Score: 170.244 bits (430), Expect = 5.251e-51
Identity = 93/224 (41.52%), Postives = 138/224 (61.61%), Query Frame = -3 
Query:  114 DFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIE----MKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 770
            D + ++    L+++   W+ ED P  D++    +  +   + E     K  G+LAG PF +AV +   C V W   +G +L   + +  +KG  N +L+AER ALN L+R  GVAT+A   S K K   W G +TG+RKTTPGFR+ EKY + +GG  THRY  + +VM+KDNH+ A G +++++  +R+  GK +KVEVEC +L EAL+A  +GAD+VMLDN 
Sbjct:    5 DLTTLLPRPRLQQFARDWLAEDAPWLDIAGWAASRRNQGGQEEAVLLCKSAGVLAGGPFFQAVCEEAGCTVQWEHRDGEWLEPVTRVATVKGRVNDLLLAERPALNALSRISGVATLAREASRKAKATGWPGLVTGTRKTTPGFRLPEKYGLLVGGAGTHRYGTTDLVMLKDNHVWAMGGVKEALDGVRALAGKTLKVEVECRSLEEALDAAAAGADIVMLDNL 228
[Close]
BLAST of SMED30032809 vs. Ensembl Mouse
Match: Qprt (quinolinate phosphoribosyltransferase [Source:MGI Symbol;Acc:MGI:1914625])

HSP 1 Score: 198.364 bits (503), Expect = 4.536e-62
Identity = 92/203 (45.32%), Postives = 128/203 (63.05%), Query Frame = -3 
Query:  114 WINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIA-NRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 719
            W+ ED P  + +++V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L     +  +KGPA+ +L+ ER ALN L R  G+A+ A   + +     W G + G+RKTTPGFR+VEKY + +GG + HRYDL  MVMVKDNH+ A GS+E++V   R   G  +KVEVEC +L EA  A ++GAD+VMLDNF
Sbjct:   22 WLQEDCPGLNFASLVTGSAPSQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWFLPEGSKLVPVVKVAEVKGPAHHLLLGERVALNTLARCSGIASAAATAVEVARSTGWTGHVAGTRKTTPGFRLVEKYGLQVGGAACHRYDLGGMVMVKDNHVVAAGSMERAVLKARQAAGFSLKVEVECSSLEEAFRAAEAGADLVMLDNF 224
[Close]
BLAST of SMED30032809 vs. UniProt/SwissProt
Match: sp|A7SG73|NADC_NEMVE (Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Fragment) OS=Nematostella vectensis OX=45351 GN=qprt PE=3 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 2.658e-75
Identity = 112/220 (50.91%), Postives = 155/220 (70.45%), Query Frame = -3 
Query:  114 DFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLS-IKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 770
            +FSL+I  VV++K+VE W+ ED P+FD    VV      A +  K  G+LAG+PF  A+F+  DC V W   EG  +   S+IG + GP NKIL+ ER ALN ++RA G+AT +  L+ +K +  W+GE+ G+RKTTPGFR+VEKYA+ +GG+STHRYDLS+M+M+KDNHI + G+I ++V   R   G  +K+EVEC +L EALEA  +GA++VMLDNF
Sbjct:    9 NFSLLIPKVVIEKHVETWLKEDTPSFDYGGFVVGSSVEKAVLLCKSDGVLAGVPFFNAIFEKLDCKVEWQNNEGDPIKAVSVIGTVTGPVNKILLGERVALNCISRASGIATKSRSLTNLKEQYQWHGEIAGTRKTTPGFRVVEKYALEVGGVSTHRYDLSTMIMLKDNHIWSTGNITRAVKNARRVGGFSMKIEVECRSLEEALEAAHAGAEIVMLDNF 228
[Close]
BLAST of SMED30032809 vs. UniProt/SwissProt
Match: sp|P43619|NADC_YEAST (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BNA6 PE=1 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 5.450e-63
Identity = 103/219 (47.03%), Postives = 147/219 (67.12%), Query Frame = -3 
Query:  105 KKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPS-------IIGIIKGPANKILMAERTALNILTRACGVATIANRL-SIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN 737
            ++ V  W++ED+P+FD    VV  +   A +  K+ GML G+PFA+ VF   +  V W   EG++L +PS       ++  I GPA  IL+AERTALNIL+R+ G+AT ++++ S+     + G + G+RKTTPG R +EKY+M +GG  THRYDLSSMVM+KDNHI A GSI  +V   R+  G  +K+EVEC + +EA EA+++GADV+MLDNF  +
Sbjct:   15 RQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFL-EPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGD 232
[Close]
BLAST of SMED30032809 vs. UniProt/SwissProt
Match: sp|Q15274|NADC_HUMAN (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3)

HSP 1 Score: 198.749 bits (504), Expect = 2.051e-61
Identity = 93/219 (42.47%), Postives = 137/219 (62.56%), Query Frame = -3 
Query:  114 FSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 767
             +L++ PV L   V+ W+ ED P  + + +V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L   + +  ++GPA+ +L+ ER ALN L R  G+A+ A       +   W G + G+RKTTPGFR+VEKY + +GG ++HRYDL  +VMVKDNH+ A G +EK+V   R      +KVEVEC +L EA++A ++GAD+V+LDNF
Sbjct:    6 LALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNF 224
[Close]
BLAST of SMED30032809 vs. UniProt/SwissProt
Match: sp|Q91X91|NADC_MOUSE (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Mus musculus OX=10090 GN=Qprt PE=1 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 3.173e-61
Identity = 92/203 (45.32%), Postives = 128/203 (63.05%), Query Frame = -3 
Query:  114 WINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIA-NRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 719
            W+ ED P  + +++V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L     +  +KGPA+ +L+ ER ALN L R  G+A+ A   + +     W G + G+RKTTPGFR+VEKY + +GG + HRYDL  MVMVKDNH+ A GS+E++V   R   G  +KVEVEC +L EA  A ++GAD+VMLDNF
Sbjct:   22 WLQEDCPGLNFASLVTGSAPSQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWFLPEGSKLVPVVKVAEVKGPAHHLLLGERVALNTLARCSGIASAAATAVEVARSTGWTGHVAGTRKTTPGFRLVEKYGLQVGGAACHRYDLGGMVMVKDNHVVAAGSMERAVLKARQAAGFSLKVEVECSSLEEAFRAAEAGADLVMLDNF 224
[Close]
BLAST of SMED30032809 vs. UniProt/SwissProt
Match: sp|Q5I0M2|NADC_RAT (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Rattus norvegicus OX=10116 GN=Qprt PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.081e-60
Identity = 94/219 (42.92%), Postives = 131/219 (59.82%), Query Frame = -3 
Query:  114 FSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 767
               ++ P  L      W+ ED P  + +++V       A +  K  G+LAG PF +A+F   +C V+W   EG+ L     +  ++GPA+ +L+ ER ALN L R  G+A+ A           W G + G+RKTTPGFR+VEKY + +GG   HRYDL  +VMVKDNH+ A GS+EK+V   R   G  +KVEVEC +L EAL+A ++GAD+VMLDNF
Sbjct:    6 LQFLLPPASLAALANSWLQEDCPGLNFASLVTGSAPAQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWLLPEGSKLVPVVKVAEVRGPAHHLLLGERVALNTLARCSGIASAAATAVEVATSTGWAGHVAGTRKTTPGFRLVEKYGLLVGGAECHRYDLGGLVMVKDNHVVAAGSMEKAVLKARQAAGFPLKVEVECSSLKEALQAAEAGADLVMLDNF 224
[Close]
BLAST of SMED30032809 vs. TrEMBL
Match: A0A443SSS7 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Leptotrombidium deliense OX=299467 GN=B4U80_07703 PE=3 SV=1)

HSP 1 Score: 226.098 bits (575), Expect = 9.784e-70
Identity = 115/223 (51.57%), Postives = 151/223 (67.71%), Query Frame = -3 
Query:  111 FSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYL-NKPSI-IGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIK-ANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFS 767
            FS I++PV+LK+    WI ED+PNFDL   +   E + AKI  K  G+LAG+PFA AVF   +C  NW   EG +L   P+  +  + G A ++L+AERT LN ++R  GVAT A R+  K++ V WNG L G+RKTTPGFRIVEKY + IGG STHRYDLS+M+M+KDNHI    GSI+ +V   R+  G + K+EVEC +  E +EA  +G D+VMLDNFS
Sbjct:    4 FSNILNPVILKELANAWIKEDLPNFDLGAALAADEEVVAKIYCKSDGVLAGIPFANAVFNELNCSPNWCFNEGEHLKGTPTTEVAYVGGKAQRVLLAERTVLNTISRCSGVATTAKRIKNKLQHVNWNGYLAGTRKTTPGFRIVEKYGLLIGGASTHRYDLSNMIMLKDNHINICGGSIKSAVEQTRAVAGFVNKIEVECRSHKEVVEAASAGVDIVMLDNFS 226
[Close]
BLAST of SMED30032809 vs. TrEMBL
Match: H2ZYP3 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Latimeria chalumnae OX=7897 GN=QPRT PE=3 SV=2)

HSP 1 Score: 223.787 bits (569), Expect = 2.410e-68
Identity = 112/228 (49.12%), Postives = 143/228 (62.72%), Query Frame = -3 
Query:  105 MDSLFDFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN 785
            M +  + S ++ PV LKK  + W+ ED P FD    VV  +   A +  K  G+LAG PF +A+F+  DC V W   EG  L     +  +KG    +L+ ER ALN L RA GVAT A R++   K   W+GE+ G+RKTTPGFR+VEKYAM +GG +THRYDLSSM+M+KDNHI + G+I  +V   R   G   K+EVEC  L EALEA +S ADVVMLDNFS  
Sbjct:    1 MTTRPELSHLLHPVTLKKLAQDWLLEDTPAFDYGGFVVGEQEETAYLLCKSPGVLAGAPFFDAIFRELDCQVEWFHPEGASLEPVCKVAAVKGKVRHLLLGERVALNCLARASGVATAARRIADLAKAAKWHGEVAGTRKTTPGFRLVEKYAMLVGGAATHRYDLSSMIMLKDNHIWSLGNISTAVREARRAGGFSTKIEVECRCLEEALEAAQSEADVVMLDNFSPQ 228
[Close]
BLAST of SMED30032809 vs. TrEMBL
Match: A0A0L8HDK0 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Octopus bimaculoides OX=37653 GN=OCBIM_22017221mg PE=3 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 3.104e-68
Identity = 103/219 (47.03%), Postives = 151/219 (68.95%), Query Frame = -3 
Query:  102 ISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSNV 755
            +SPV ++     WI ED PNFD    VV  + + A + M++ G+LAG PF +AVFK  +C++ W   EGTYLN    + IIKG    +L+ ER ALN   RA G+AT+A +L++K + V W G+L  +R+TTPGFR+VEKY++++GG++THRYDLSSM++++DNHI   GSI+K+V   +   G  +K+EVEC NL +ALEA  +G DV++ +N ++ V
Sbjct:   31 LSPVTVQHLAREWIKEDSPNFDFGGFVVGEKKVTAALIMRQAGVLAGRPFIDAVFKELECEIEWLYPEGTYLNPVQTVAIIKGRVRCLLLGERVALNCACRASGLATLARKLALKAEGVGWKGKLADTRRTTPGFRLVEKYSLFVGGLATHRYDLSSMIILRDNHIWTAGSIQKAVKDAKLVSGFSMKIEVECRNLEDALEAANAGCDVILFENPTAEV 249
[Close]
BLAST of SMED30032809 vs. TrEMBL
Match: A0A210QTU2 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT15718 PE=3 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 1.600e-67
Identity = 109/218 (50.00%), Postives = 145/218 (66.51%), Query Frame = -3 
Query:  111 IISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV--WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFS 758
            I+ PV L+  V  W+ ED PNFD    VV  +   A + MK  G+LAG PF +AVFK  DC V W+  EG Y+   + +  + G   ++L+ ER ALN L+RA G+A+ A R+  KI +   W GE+ G+RKTTPGFR+VEKY++ +GG+STHRYDLSSM+M+KDNHI   G+I K+V   R   G   KVEVEC ++ +A EA ++G DVVMLDNFS
Sbjct:   19 ILHPVTLQHMVREWLKEDTPNFDYGGFVVGEKEETAVLLMKSAGVLAGNPFFDAVFKELDCKVTWSSPEGDYIEPVTRVATVTGKVRQLLLGERVALNCLSRASGIASAAGRMR-KIAETAGWCGEIAGTRKTTPGFRLVEKYSLLVGGVSTHRYDLSSMIMLKDNHIWTAGNITKAVSDARVVGGFSTKVEVECRSVKDATEAAEAGCDVVMLDNFS 235
[Close]
BLAST of SMED30032809 vs. TrEMBL
Match: K1RLF1 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Crassostrea gigas OX=29159 GN=CGI_10018767 PE=3 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 3.017e-67
Identity = 105/214 (49.07%), Postives = 148/214 (69.16%), Query Frame = -3 
Query:   81 WINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLS-IKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSNVRIIVNMN 719
            W+ ED PNFD    VV  +   A + +K  G+LAG PF EA+FK  DC V+W   EG +L     +  + G   ++L+ ER ALN L+RA G+A++A +L+ IK +  W GE+ G+RKTTPGFR+VEKYA+ +G +STHR+DLSSM+M+KDNHI  +GSI ++V   +   G  +KVEVEC +++EALEA ++G+D++MLDNFSS  R+I   N
Sbjct:    5 WLKEDTPNFDYGGFVVGEKEETALLLIKSPGVLAGKPFFEAIFKELDCVVSWEYDEGEFLEPIQCVAKVTGKVRQLLLGERVALNCLSRASGIASLARQLAKIKERVGWKGEIAGTRKTTPGFRLVEKYALMVGSVSTHRHDLSSMIMLKDNHIWTSGSITQAVKDAKIVGGFSLKVEVECRSVDEALEAAEAGSDIIMLDNFSSEARLIFIRN 218
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BLAST of SMED30032809 vs. Ensembl Yeast
Match: BNA6 (Quinolinate phosphoribosyl transferase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [Source:SGD;Acc:S000001943])

HSP 1 Score: 202.986 bits (515), Expect = 7.849e-65
Identity = 103/219 (47.03%), Postives = 147/219 (67.12%), Query Frame = -3 
Query:  105 KKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPS-------IIGIIKGPANKILMAERTALNILTRACGVATIANRL-SIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN 737
            ++ V  W++ED+P+FD    VV  +   A +  K+ GML G+PFA+ VF   +  V W   EG++L +PS       ++  I GPA  IL+AERTALNIL+R+ G+AT ++++ S+     + G + G+RKTTPG R +EKY+M +GG  THRYDLSSMVM+KDNHI A GSI  +V   R+  G  +K+EVEC + +EA EA+++GADV+MLDNF  +
Sbjct:   15 RQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFL-EPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGD 232
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BLAST of SMED30032809 vs. Ensembl Nematostella
Match: QPRT (Nicotinate-nucleotide pyrophosphorylase [carboxylating] [Source:UniProtKB/Swiss-Prot;Acc:A7SG73])

HSP 1 Score: 234.187 bits (596), Expect = 1.089e-76
Identity = 112/220 (50.91%), Postives = 155/220 (70.45%), Query Frame = -3 
Query:  114 DFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLS-IKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 770
            +FSL+I  VV++K+VE W+ ED P+FD    VV      A +  K  G+LAG+PF  A+F+  DC V W   EG  +   S+IG + GP NKIL+ ER ALN ++RA G+AT +  L+ +K +  W+GE+ G+RKTTPGFR+VEKYA+ +GG+STHRYDLS+M+M+KDNHI + G+I ++V   R   G  +K+EVEC +L EALEA  +GA++VMLDNF
Sbjct:    9 NFSLLIPKVVIEKHVETWLKEDTPSFDYGGFVVGSSVEKAVLLCKSDGVLAGVPFFNAIFEKLDCKVEWQNNEGDPIKAVSVIGTVTGPVNKILLGERVALNCISRASGIATKSRSLTNLKEQYQWHGEIAGTRKTTPGFRVVEKYALEVGGVSTHRYDLSTMIMLKDNHIWSTGNITRAVKNARRVGGFSMKIEVECRSLEEALEAAHAGAEIVMLDNF 228
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BLAST of SMED30032809 vs. Ensembl Nematostella
Match: EDO25477 (Nicotinate-nucleotide pyrophosphorylase [carboxylating] [Source:UniProtKB/TrEMBL;Acc:A8DWD2])

HSP 1 Score: 97.0561 bits (240), Expect = 4.793e-24
Identity = 69/209 (33.01%), Postives = 112/209 (53.59%), Query Frame = -3 
Query:  111 VEFWINEDIPNFDLSTIVVNHESI-NAKIEMKEKGMLAGLPFAEAVFKYFD--CDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFS 728
            V   + EDI + D++  ++  E + +AK+  +E  ++ G  + +AVF+  D    V+W+  +G       ++  ++GPA  +L  ER+ALN L     VAT     +  ++     +L  +RKT PG R+ +KYA+  GG   HR  L    ++K+NHI A G I ++V     KI     VEVE  +L E  +A+ +GAD++MLD  S
Sbjct:   17 VRRALAEDIGSGDITAQLIPAERLAHAKVITRESTVICGTAWVDAVFRQLDPRVAVHWHIQDGQRAKPNQVLFELEGPARALLSGERSALNFLQTLSAVATRCQHYADLVQGTAV-KLLDTRKTLPGLRLAQKYAVTQGGCHNHRIGLYDAFLIKENHIAACGGIAQAV-TTAHKIAPGKPVEVEVESLEELRQALDAGADIIMLDELS 223
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BLAST of SMED30032809 vs. Ensembl Medaka
Match: QPRT (nicotinate-nucleotide pyrophosphorylase [carboxylating] [Source:NCBI gene;Acc:110016076])

HSP 1 Score: 191.815 bits (486), Expect = 1.524e-59
Identity = 104/213 (48.83%), Postives = 135/213 (63.38%), Query Frame = -3 
Query:  114 LKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKE-KGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKP--SIIGIIKGPANKILMAERTALNILTRACGVATIANRL-SIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNF 740
            L +    W+ ED PNFD + + V  E   A++  K  + +LAG PF  AVF    C V+W   EG  L     +I  +++GPA  +L+ ER ALN L RA G+AT  +RL SI     W+GE+ G+RKTTPGFR+VEKYAM +GG S HR DLS MVM+KDNH+ A+GSI K+V   RS      K+EVEC ++ E  EA  +GAD+VMLDNF
Sbjct:   17 LTRLAREWLAEDTPNFDPAGVCVGSEEAEARLLCKSPRTVLAGCPFFTAVFNEVGCTVDWIYQEGAELGPEVVTITAVVRGPARDLLLGERPALNCLARASGIATRCSRLQSIANAAGWHGEVAGTRKTTPGFRLVEKYAMLVGGASMHRQDLSGMVMLKDNHVWASGSITKAVKETRSVCSFSSKIEVECQSIAEGREAAAAGADIVMLDNF 229
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BLAST of SMED30032809 vs. Ensembl Medaka
Match: ENSORLT00000032651.1 (nicotinate-nucleotide pyrophosphorylase [carboxylating]-like [Source:NCBI gene;Acc:111947394])

HSP 1 Score: 159.458 bits (402), Expect = 1.408e-47
Identity = 79/172 (45.93%), Postives = 104/172 (60.47%), Query Frame = -3 
Query:  237 LKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKE-KGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKP--SIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKV-WNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEK 740
            L +    W+ ED PNFD + + V  E   A++  K  + +LAG PF  AVF    C V+W   EG  L     +I  +++GPA  +L+ ER ALN L R  G+AT  +RL    K   W+ E+ G+RKTTPGFR+VEKYAM +GG S HR DLS MVM+ DNH+  +GSI K
Sbjct:   17 LTRLAREWLAEDTPNFDPAGVCVGSEEAEARLLCKSPRTVLAGCPFFTAVFNEVGCTVDWIYQEGAELGPEVVTITAVVRGPARDLLLGERPALNCLARGSGIATCCSRLQSFAKAAGWHEEVAGTRKTTPGFRLVEKYAMLVGGASMHRQDLSGMVMLMDNHVWTSGSITK 188
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BLAST of SMED30032809 vs. Planmine SMEST
Match: SMESG000080771.1 (SMESG000080771.1)

HSP 1 Score: 469.159 bits (1206), Expect = 1.137e-165
Identity = 227/227 (100.00%), Postives = 227/227 (100.00%), Query Frame = -3 
Query:  105 MDSLFDFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN 785
            MDSLFDFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN
Sbjct:    1 MDSLFDFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESINAKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGPANKILMAERTALNILTRACGVATIANRLSIKIKKVWNGELTGSRKTTPGFRIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGKLIKVEVECGNLNEALEAVKSGADVVMLDNFSSN 227
The following BLAST results are available for this feature:
BLAST of SMED30032809 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
QPRT4.271e-6242.47quinolinate phosphoribosyltransferase [Source:HGNC... [more]
QPRT4.271e-6242.47quinolinate phosphoribosyltransferase [Source:HGNC... [more]
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BLAST of SMED30032809 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30032809 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30032809 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30032809 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
QPRT5.251e-5141.52quinolinate phosphoribosyltransferase [Source:NCBI... [more]
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BLAST of SMED30032809 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Qprt4.536e-6245.32quinolinate phosphoribosyltransferase [Source:MGI ... [more]
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BLAST of SMED30032809 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7SG73|NADC_NEMVE2.658e-7550.91Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
sp|P43619|NADC_YEAST5.450e-6347.03Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
sp|Q15274|NADC_HUMAN2.051e-6142.47Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
sp|Q91X91|NADC_MOUSE3.173e-6145.32Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
sp|Q5I0M2|NADC_RAT2.081e-6042.92Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
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BLAST of SMED30032809 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A443SSS79.784e-7051.57Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
H2ZYP32.410e-6849.12Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
A0A0L8HDK03.104e-6847.03Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
A0A210QTU21.600e-6750.00Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
K1RLF13.017e-6749.07Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
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BLAST of SMED30032809 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30032809 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30032809 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
BNA67.849e-6547.03Quinolinate phosphoribosyl transferase; required f... [more]
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BLAST of SMED30032809 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
QPRT1.089e-7650.91Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
EDO254774.793e-2433.01Nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
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BLAST of SMED30032809 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
QPRT1.524e-5948.83nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
ENSORLT00000032651.11.408e-4745.93nicotinate-nucleotide pyrophosphorylase [carboxyla... [more]
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BLAST of SMED30032809 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000080771.11.137e-165100.00SMESG000080771.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032809 ID=SMED30032809|Name=SMED30032809|organism=Schmidtea mediterranea sexual|type=transcript|length=805bp
GTAAACTAAACAAGTTCCGCATTTTAATAATATATAAATAATTATATTCT
GTGTGTCGTAAAATCGTTACCTGTATAATTATTCATATTTACAATAATTC
TTACGTTAGAACTAAAGTTATCCAGCATAACAACATCAGCCCCTGACTTA
ACTGCTTCTAAAGCTTCATTTAAATTACCACATTCAACTTCAACTTTTAT
CAATTTTCCAATTTTTGATCTTAATAAATGAACTGATTTTTCTATACTCC
CATTAGCTTTAATGTGATTATCTTTGACCATAACCATAGATGACAAATCA
TATCGATGTGTTGAAATACCGCCTATATACATAGCGTATTTTTCTACTAT
TCTGAATCCTGGAGTTGTTTTACGGCTACCAGTAAGTTCACCATTCCAAA
CCTTTTTTATTTTAATAGACAATCTATTAGCAATCGTTGCCACTCCGCAA
GCTCGAGTCAGTATATTGAGAGCAGTTCTTTCTGCCATTAAAATTTTGTT
TGCAGGACCTTTGATTATACCAATGATCGAAGGCTTATTTAAGTAAGTTC
CTTCTAACTCATTCCAATTCACATCACAATCAAAATACTTGAAAACGGCT
TCAGCAAATGGTAGTCCAGCCAACATTCCTTTTTCCTTCATTTCGATTTT
AGCATTAATAGACTCATGATTTACAACAATTGTAGATAAATCAAAATTTG
GAATATCTTCATTAATCCAAAATTCGACGTACTTTTTCAGAACGACAGGA
CTAATAATCAAAGAAAAATCAAACAAAGAATCCATAGTATGTTTATTTCG
AAAAG
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protein sequence of SMED30032809-orf-1

>SMED30032809-orf-1 ID=SMED30032809-orf-1|Name=SMED30032809-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=254bp
FRNKHTMDSLFDFSLIISPVVLKKYVEFWINEDIPNFDLSTIVVNHESIN
AKIEMKEKGMLAGLPFAEAVFKYFDCDVNWNELEGTYLNKPSIIGIIKGP
ANKILMAERTALNILTRACGVATIANRLSIKIKKVWNGELTGSRKTTPGF
RIVEKYAMYIGGISTHRYDLSSMVMVKDNHIKANGSIEKSVHLLRSKIGK
LIKVEVECGNLNEALEAVKSGADVVMLDNFSSNVRIIVNMNNYTGNDFTT
HRI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR037128Quinolinate_PRibosylTase_N_sf
IPR004393NadC
IPR036068Nicotinate_pribotase-like_C
IPR013785Aldolase_TIM
IPR022412Quinolinate_PRibosylTrfase_N
IPR002638Quinolinate_PRibosylTrfase_C
IPR027277NadC/ModD
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0016763transferase activity, transferring pentosyl groups
GO:0004514nicotinate-nucleotide diphosphorylase (carboxylating) activity
Vocabulary: biological process
TermDefinition
GO:0009435NAD biosynthetic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR037128Quinolinate phosphoribosyl transferase, N-terminal domain superfamilyGENE3DG3DSA:3.90.1170.20coord: 24..136
e-value: 3.0E-79
score: 267.3
IPR022412Quinolinate phosphoribosyl transferase, N-terminalPFAMPF02749QRPTase_Ncoord: 35..119
e-value: 8.0E-21
score: 73.9
IPR002638Quinolinate phosphoribosyl transferase, C-terminalPFAMPF01729QRPTase_Ccoord: 121..238
e-value: 3.4E-36
score: 124.5
IPR004393Nicotinate-nucleotide pyrophosphorylaseTIGRFAMTIGR00078TIGR00078coord: 26..233
e-value: 4.3E-72
score: 240.5
IPR027277Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModDPIRSFPIRSF006250NadC_ModDcoord: 16..249
e-value: 3.0E-65
score: 217.7
IPR027277Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModDPANTHERPTHR32179FAMILY NOT NAMEDcoord: 20..232
IPR013785Aldolase-type TIM barrelGENE3DG3DSA:3.20.20.70coord: 137..231
e-value: 3.0E-79
score: 267.3
NoneNo IPR availablePANTHERPTHR32179:SF3NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]coord: 20..232
NoneNo IPR availableSUPERFAMILYSSF54675Nicotinate/Quinolinate PRTase N-terminal domain-likecoord: 21..120
IPR036068Nicotinate phosphoribosyltransferase-like, C-terminalSUPERFAMILYSSF51690Nicotinate/Quinolinate PRTase C-terminal domain-likecoord: 121..233