Cyclin-dependent kinase 1

Overview
NameCyclin-dependent kinase 1
Smed IDSMED30032688
Length (bp)1095
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cyclin-dependent kinase 1 (SMED30032688) t-SNE clustered cells

Violin plots show distribution of expression levels for Cyclin-dependent kinase 1 (SMED30032688) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cyclin-dependent kinase 1 (SMED30032688) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cyclin-dependent kinase 1 (SMED30032688) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032688

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30032688SMESG000052413.1 SmedASXL_009733SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30032688SMESG000052413.1 dd_Smed_v4_11265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30032688SMESG000052413.1 dd_Smed_v6_11265_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
zeta neoblastSMED30032688SMESG000052413.1 dd_Smed_v4_11265_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30032688SMESG000052413.1 SMED_30280_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SMED_30280_V2_1GPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SMED_23329_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SMED_23329_V2_1GPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SmWIOct06_014611GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SMED_26200_V2_1GPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30032688SMESG000052413.1 SMED_26200_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK1 (cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722])

HSP 1 Score: 344.739 bits (883), Expect = 7.676e-118
Identity = 160/292 (54.79%), Postives = 219/292 (75.00%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLD 921
            + D+T+IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKELRHPNIV LQ  + +  +LYL+FE+L+MDL++YLD+      M+  ++K + YQI+QG+++CH+RR +HRDLKPQNLL+D +K  IKLADFGLAR +G P++  THEVVTLWYR+PEV+L + RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    +  V+ +DEN  DLL KML+Y P +R + + AL H YF DLD
Sbjct:    1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK1 (cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722])

HSP 1 Score: 342.813 bits (878), Expect = 5.177e-117
Identity = 158/292 (54.11%), Postives = 218/292 (74.66%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLD 921
            + D+T+IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKELRHPNIV LQ  + +  +LYL+FE+L+MDL++YLD+      M+  ++K + YQI+QG+++CH+RR +HRDLKPQNLL+D +K  IKLADFGLAR +G P++  THE +TLWYR+PEV+L + RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    +  V+ +DEN  DLL KML+Y P +R + + AL H YF DLD
Sbjct:    1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK2 (cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771])

HSP 1 Score: 322.398 bits (825), Expect = 5.081e-109
Identity = 153/294 (52.04%), Postives = 209/294 (71.09%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDI---ILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+L+ DL++++D   + +  I   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++T    IKLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEM+T + LF GDSEIDQLF IF+ LGTPD  VWP +   P + P FP W     S++V  +DE+   LL +ML Y P +R + + AL H +F D+ K
Sbjct:    1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEG-AIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK3 (cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772])

HSP 1 Score: 303.138 bits (775), Expect = 2.005e-101
Identity = 143/292 (48.97%), Postives = 204/292 (69.86%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN---EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKS 927
            F ++EKIGEGTYG+VYK+ N+ T +  A+KKIR + + +G+  T +REIS+LKEL+HPNIV L   +  + KLYLVFE+L+ DL++Y+D+    E P++  ++K + +Q++QG+ +CH+ R +HRDLKPQNLL++     IKLADFGLAR +G P++  THEVVTLWYRAPE++L +K Y+ A+D+WS+ CI AEM+T K LF GDSEIDQLF IF++LGTP    WP + + P +   FP W       +V  ++    DLL ++L Y P +R   + AL H YF+  + S
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLH--LIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPS 292          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Match: CDK3 (cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:HGNC:1772])

HSP 1 Score: 303.138 bits (775), Expect = 2.005e-101
Identity = 143/292 (48.97%), Postives = 204/292 (69.86%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN---EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKS 927
            F ++EKIGEGTYG+VYK+ N+ T +  A+KKIR + + +G+  T +REIS+LKEL+HPNIV L   +  + KLYLVFE+L+ DL++Y+D+    E P++  ++K + +Q++QG+ +CH+ R +HRDLKPQNLL++     IKLADFGLAR +G P++  THEVVTLWYRAPE++L +K Y+ A+D+WS+ CI AEM+T K LF GDSEIDQLF IF++LGTP    WP + + P +   FP W       +V  ++    DLL ++L Y P +R   + AL H YF+  + S
Sbjct:    4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLH--LIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPS 292          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-1 (Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:P34556])

HSP 1 Score: 335.88 bits (860), Expect = 2.509e-114
Identity = 161/311 (51.77%), Postives = 223/311 (71.70%), Query Frame = 1
Query:   46 YQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLD----NEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYD-LRSRLVE------VIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACD 945
            Y L+DFT++EKIGEGTYG+VYK  N+ TN   A+KKIR E++++G+  T +REIS+LKEL+HPN+V L+  I ++ +L+L+FE+L+ DL+RY+D    +E  P+    LK +++QI+Q + +CH RR +HRDLKPQNLLVD N   IKLADFGLAR  G P++  THEVVTLWYRAPE+++ A+RYS  +D+WS+ CI AEM T KPLF+GDSEID+LF IF+VLGTP    W  ++  P +   FP WR + LR +  +      ++D+  F LLE +L+Y P  R N + AL+H YF ++D S LPA +
Sbjct:   17 YTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLE--TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNG-AIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMDTSKLPAGN 324          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-1 (Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:P34556])

HSP 1 Score: 335.88 bits (860), Expect = 2.509e-114
Identity = 161/311 (51.77%), Postives = 223/311 (71.70%), Query Frame = 1
Query:   46 YQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLD----NEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYD-LRSRLVE------VIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACD 945
            Y L+DFT++EKIGEGTYG+VYK  N+ TN   A+KKIR E++++G+  T +REIS+LKEL+HPN+V L+  I ++ +L+L+FE+L+ DL+RY+D    +E  P+    LK +++QI+Q + +CH RR +HRDLKPQNLLVD N   IKLADFGLAR  G P++  THEVVTLWYRAPE+++ A+RYS  +D+WS+ CI AEM T KPLF+GDSEID+LF IF+VLGTP    W  ++  P +   FP WR + LR +  +      ++D+  F LLE +L+Y P  R N + AL+H YF ++D S LPA +
Sbjct:   17 YTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLE--TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNG-AIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMDTSKLPAGN 324          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-2 (Cyclin-dependent kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:O61847])

HSP 1 Score: 275.404 bits (703), Expect = 1.975e-90
Identity = 135/288 (46.88%), Postives = 194/288 (67.36%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDII----LKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRS-RLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 909
            F  + +IGEGTYG+V+K+I+   N   A+K IR++ DE+GI  T LREIS +K+L+H NIV L   I    KLY+VFE+++ DL+  L+  E P N ++    +K F +Q++  L YCH RR +HRDLKPQN+LV ++  +IK+ADFGLAR +  P +N THEVVTLWYR PE++L ++RYS ++D+WS+ CI +E+ + KPLF G+ EI QLF IF+++GTP+ K WP +D FP +  +FP W  +L+       +  N  D+L ++L Y P  R   + AL H YF
Sbjct:   15 FCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIYANSKLYMVFEFIDRDLKNLLEMLE-PTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILV-SDSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYPPERRLTAKGALSHRYF 300          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: cdk-5 (Cyclin-dependent-like kinase 5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECH7])

HSP 1 Score: 257.684 bits (657), Expect = 3.329e-84
Identity = 128/288 (44.44%), Postives = 189/288 (65.62%), Query Frame = 1
Query:   58 DFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITY-KPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLR-SRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            ++ ++EKIGEGTYG V+K+ NK + E  A+K++R ++D++G+  + LREI IL+EL+H N+V L   +  + KL LVFEY + DL+++ D+    M+    +    Q+++GL +CH    +HRDLKPQNLL++TN   +KLADFGLAR +G PV+  + EVVTLWYR P+V+  AK Y+ +ID+WS  CI AE+    +PLF G    DQL  IFK LG+P    WP + + P + P +P++   L  S++V  ++    DLL+K+LV +P  R +   AL H YFAD
Sbjct:    3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNG-TLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKP-YPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Match: pct-1 (Cyclin-dependent kinase 17 [Source:UniProtKB/Swiss-Prot;Acc:Q8I7M8])

HSP 1 Score: 233.032 bits (593), Expect = 2.576e-71
Identity = 123/288 (42.71%), Postives = 180/288 (62.50%), Query Frame = 1
Query:   49 QLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPV-WRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 909
            +L  + +++K+GEGTY  V++  + +TN+F A+K+IR E +E G   T +RE+S+L+ LRH N+V L   I     L LVFEY++ DL++Y+D+  N M    ++ F YQ+++GL YCH RR +HRDLKPQNLL+ T K  +KLADFGLAR    P K  ++EVVTLWYR P+V+L +  YS  ID+W V CI+ EMI  + LF G +  +QL  IF+ LG+P     P + + P + P     +  D   R +  ID + F+LL K L Y   +R +  +A+ H + 
Sbjct:  234 KLETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEE-GAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLI-TAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL 519          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk1 (gene:FBgn0004106 transcript:FBtr0080051)

HSP 1 Score: 325.865 bits (834), Expect = 1.090e-110
Identity = 146/288 (50.69%), Postives = 210/288 (72.92%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 909
            + DF +IEKIGEGTYG+VYK  N++T +  A+KKIR E+D++G+  T +REIS+LKEL+H NIV L+  + E+ ++YL+FE+L+MDL++Y+D+   +  M   +++ + YQI   +L+CH RR +HRDLKPQNLL+D +  +IK+ADFGL R +G PV+  THE+VTLWYRAPEV+L + RYSC +D+WS+ CI AEM T KPLF+GDSEIDQLF +F++L TP   +WP +   P +   FP W  +  +  ++ +D N  DL++KML+Y P+ R + +D L H YF
Sbjct:    1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSG-LIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083922)

HSP 1 Score: 276.944 bits (707), Expect = 2.702e-91
Identity = 142/298 (47.65%), Postives = 197/298 (66.11%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDEN-LFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSD 930
            M+  L +F R EKIGEGTYGIVYK+ +  T +  A+KKIR E + +G+  T +REIS+LK L+HPN+V L   +     LY++FEYLNMDL++ +D +++     ++K + +QI+  + +CHT R +HRDLKPQNLLVDT    IKLADFGLAR +  P++  THEVVTLWYRAPE++L  K YS  +D+WS+ CI +EMI  + LF GDSEIDQL+ IF+ L TPD   WP + + P +   FP W     + + + I E+   +L+  ML Y P  R + +DAL H YF ++   D
Sbjct:    1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWE---GTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVD 294          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0300447)

HSP 1 Score: 276.944 bits (707), Expect = 2.702e-91
Identity = 142/298 (47.65%), Postives = 197/298 (66.11%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDEN-LFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSD 930
            M+  L +F R EKIGEGTYGIVYK+ +  T +  A+KKIR E + +G+  T +REIS+LK L+HPN+V L   +     LY++FEYLNMDL++ +D +++     ++K + +QI+  + +CHT R +HRDLKPQNLLVDT    IKLADFGLAR +  P++  THEVVTLWYRAPE++L  K YS  +D+WS+ CI +EMI  + LF GDSEIDQL+ IF+ L TPD   WP + + P +   FP W     + + + I E+   +L+  ML Y P  R + +DAL H YF ++   D
Sbjct:    1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWE---GTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVD 294          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083921)

HSP 1 Score: 276.944 bits (707), Expect = 2.702e-91
Identity = 142/298 (47.65%), Postives = 197/298 (66.11%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDEN-LFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSD 930
            M+  L +F R EKIGEGTYGIVYK+ +  T +  A+KKIR E + +G+  T +REIS+LK L+HPN+V L   +     LY++FEYLNMDL++ +D +++     ++K + +QI+  + +CHT R +HRDLKPQNLLVDT    IKLADFGLAR +  P++  THEVVTLWYRAPE++L  K YS  +D+WS+ CI +EMI  + LF GDSEIDQL+ IF+ L TPD   WP + + P +   FP W     + + + I E+   +L+  ML Y P  R + +DAL H YF ++   D
Sbjct:    1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-IKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWE---GTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVD 294          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Match: Cdk5 (gene:FBgn0013762 transcript:FBtr0087350)

HSP 1 Score: 257.299 bits (656), Expect = 7.999e-84
Identity = 129/298 (43.29%), Postives = 188/298 (63.09%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMI-TYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN--PLFPV---WRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKS 927
            +  + ++EKIGEGTYG V+K  N+ T E  A+K++R + D++G+  + LREI +LKEL+H NIV L   +    KL LVFE+ + DL++Y D+    ++  + + F  Q+++GL +CH+   +HRDLKPQNLL++ N   +KLADFGLAR +G PVK  + EVVTLWYR P+V+  AK Y+ +ID+WS  CI+AE+    +PLF G   +DQL  IF+VLGTP+   WP +     +   P FP    W     S+LV  ++    DLL+K+L+  P +R +   A+ H YF D   S
Sbjct:    1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGE-LKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSW-----SQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSS 292          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 363.229 bits (931), Expect = 3.086e-125
Identity = 170/302 (56.29%), Postives = 229/302 (75.83%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENP--MNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  NK T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+  +   M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWPD++  P +   FP W+    +  V+ +D+N  DLL KML+Y P +R + R A+ H YF DLDKS LPA +L+
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGEFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLANTVKNLDKNGIDLLMKMLIYDPPKRISARQAMTHPYFDDLDKSSLPASNLK 301          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 363.229 bits (931), Expect = 3.086e-125
Identity = 170/302 (56.29%), Postives = 229/302 (75.83%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENP--MNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  NK T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+  +   M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWPD++  P +   FP W+    +  V+ +D+N  DLL KML+Y P +R + R A+ H YF DLDKS LPA +L+
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGEFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLANTVKNLDKNGIDLLMKMLIYDPPKRISARQAMTHPYFDDLDKSSLPASNLK 301          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 328.946 bits (842), Expect = 9.193e-112
Identity = 152/290 (52.41%), Postives = 211/290 (72.76%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L+  I  + KLYLVFE+L+ DL+R++D+   + ++  ++K + +Q++QGL +CH+ R +HRDLKPQNLL++    I KLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEMIT + LF GDSEIDQLF IF+ LGTPD  +WP +   P + P FP W     S++V  +DE+  DLL +ML Y P +R + ++AL+H +F D+
Sbjct:    1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLRDVIHTENKLYLVFEFLHQDLKRFMDSTSVSGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDESIWPGVTSMPDYKPSFPKWARQDLSKVVPPLDEDGRDLLGQMLTYDPNKRISAKNALVHRFFRDV 289          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: cdk5 (cyclin-dependent kinase 5 [Source:ZFIN;Acc:ZDB-GENE-010131-2])

HSP 1 Score: 267.314 bits (682), Expect = 8.953e-88
Identity = 133/293 (45.39%), Postives = 196/293 (66.89%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITY-KPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVI---DENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  + ++EKIGEGTYG V+K+ N+ T+E  A+K++R ++D++G+  + LREI +LKEL+H NIV L   +    KL LVFEY + DL++Y D+    ++  I+K F YQ+++GL +CH+R  +HRDLKPQNLL++ N   +KLADFGLAR +G PV+  + EVVTLWYR P+V+  AK YS +ID+WS  CI AE+    +PLF G+   DQL  IF++LGTP  + W  ++K P + P +P+  Y   + LV V+        DLL+ +L  +P++R +  +AL H YFAD 
Sbjct:    1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGE-LKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWQTMNKLPDYKP-YPM--YPATTSLVNVVPKLSSTGRDLLQNLLKCNPVQRISAEEALQHPYFADF 289          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Match: CDK18 (si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-51])

HSP 1 Score: 246.899 bits (629), Expect = 1.758e-77
Identity = 131/308 (42.53%), Postives = 191/308 (62.01%), Query Frame = 1
Query:   49 QLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDL---DKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYS 963
            +L  + ++ K+GEGTY  V+K  +K+T    A+K+IR E++E G   T +RE+S+LK L+H NIV L   I     L LVFEYL+ DL++YLDN  N M+   +K F +Q+++GL YCH R+ +HRDLKPQNLL++ +K  +KLADFGLAR    P K  ++EVVTLWYR P+V+L +  YS  ID+W V CI+ EM T +P+F G +  ++L  IF+++GTP  + WP +   ++F  +  LFP +R       V  +D    DLL  +L+Y    R +   +L H YF  L ++ L   D    +S
Sbjct:  131 KLETYVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHEE-GAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLTLVFEYLDSDLKQYLDNCGNLMSMHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLIN-DKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEESWPGITANEEFKSY--LFPQYRAQALINHVPRLDTEGIDLLTALLLYDTKRRISAELSLRHSYFQTLGENILSIPDTSSVFS 434          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 354.755 bits (909), Expect = 8.467e-122
Identity = 167/298 (56.04%), Postives = 226/298 (75.84%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA 939
            + ++T+IEKIGEGTYG+VYK  +K T +  A+KKIR EN+E+G+  T +REIS+LKEL+HPNIV L   + +  +LYL+FE+L+MDL++YLD+      ++ +++K + YQI+QG+++CH+RR +HRDLKPQNLL+D+ K +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    S  V+ ID++  DLL KML+Y P +R + R ALLH YF DLDKS LPA
Sbjct:    1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDS-KGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPA 297          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 335.88 bits (860), Expect = 2.124e-114
Identity = 159/285 (55.79%), Postives = 214/285 (75.09%), Query Frame = 1
Query:   91 TYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA 939
            TYG+VYK  +K T +  A+KKIR EN+E+G+  T +REIS+LKEL+HPNIV L   + +  +LYL+FE+L+MDL++YLD+      ++ +++K + YQI+QG+++CH+RR +HRDLKPQNLL+D+ K +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    S  V+ ID++  DLL KML+Y P +R + R ALLH YF DLDKS LPA
Sbjct:    7 TYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDS-KGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPA 290          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cfap65 (cilia and flagella associated protein 65 [Source:Xenbase;Acc:XB-GENE-1001102])

HSP 1 Score: 335.109 bits (858), Expect = 4.438e-114
Identity = 159/285 (55.79%), Postives = 214/285 (75.09%), Query Frame = 1
Query:   91 TYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA 939
            TYG+VYK  +K T +  A+KKIR EN+E+G+  T +REIS+LKEL+HPNIV L   + +  +LYL+FE+L+MDL++YLD+      ++ +++K + YQI+QG+++CH+RR +HRDLKPQNLL+D+ K +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    S  V+ ID++  DLL KML+Y P +R + R ALLH YF DLDKS LPA
Sbjct:   12 TYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDS-KGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPA 295          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cdk2 (cyclin-dependent kinase 2 [Source:NCBI gene;Acc:493498])

HSP 1 Score: 314.309 bits (804), Expect = 5.900e-106
Identity = 148/292 (50.68%), Postives = 207/292 (70.89%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ N+ T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+LN DL++++D    + ++  ++K + +Q++QGL +CH+ R +HRDLKPQNLL+++ +  IKLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEMIT + LF GDSEIDQLF IF+ LGTPD   WP +   P +   FP W     S++V  +D++  DLL +ML Y   +R + + AL H +F D+ +
Sbjct:    1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINS-EGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDYKSTFPKWVRQDFSKVVPPLDDDGRDLLAQMLQYDSNKRISAKAALTHAFFRDVSR 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Match: cdk2 (cyclin-dependent kinase 2 [Source:NCBI gene;Acc:493498])

HSP 1 Score: 300.442 bits (768), Expect = 3.837e-100
Identity = 148/316 (46.84%), Postives = 207/316 (65.51%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEM------------------------ITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ N+ T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+LN DL++++D    + ++  ++K + +Q++QGL +CH+ R +HRDLKPQNLL+++ +  IKLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEM                        IT + LF GDSEIDQLF IF+ LGTPD   WP +   P +   FP W     S++V  +D++  DLL +ML Y   +R + + AL H +F D+ +
Sbjct:    1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINS-EGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSLGCIFAEMQECRPNIAEFCRQDENNGCNVFHTITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDYKSTFPKWVRQDFSKVVPPLDDDGRDLLAQMLQYDSNKRISAKAALTHAFFRDVSR 315          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk1 (cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:MGI:88351])

HSP 1 Score: 341.658 bits (875), Expect = 7.966e-117
Identity = 158/292 (54.11%), Postives = 219/292 (75.00%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLD 921
            + D+ +IEKIGEGTYG+VYK  +++T +  A+KKIR E++E+G+  T +REIS+LKELRHPNIV LQ  + +  +LYL+FE+L+MDL++YLD+      M+  ++K + +QI+QG+++CH+RR +HRDLKPQNLL+D +K  IKLADFGLAR +G P++  THEVVTLWYR+PEV+L + RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    +  V+ +DEN  DLL KMLVY P +R + + AL H YF DLD
Sbjct:    1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLD 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk1 (cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:MGI:88351])

HSP 1 Score: 341.658 bits (875), Expect = 7.966e-117
Identity = 158/292 (54.11%), Postives = 219/292 (75.00%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLD 921
            + D+ +IEKIGEGTYG+VYK  +++T +  A+KKIR E++E+G+  T +REIS+LKELRHPNIV LQ  + +  +LYL+FE+L+MDL++YLD+      M+  ++K + +QI+QG+++CH+RR +HRDLKPQNLL+D +K  IKLADFGLAR +G P++  THEVVTLWYR+PEV+L + RYS  +D+WS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    +  V+ +DEN  DLL KMLVY P +R + + AL H YF DLD
Sbjct:    1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLD 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk2 (cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:MGI:104772])

HSP 1 Score: 321.242 bits (822), Expect = 9.820e-109
Identity = 152/294 (51.70%), Postives = 208/294 (70.75%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDI---ILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+L+ DL++++D   + +  I   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++    I KLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEM+T + LF GDSEIDQLF IF+ LGTPD  VWP +   P + P FP W     S++V  +DE+   LL +ML Y P +R + + AL H +F D+ K
Sbjct:    1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk3 (cyclin-dependent kinase 3 [Source:MGI Symbol;Acc:MGI:1916931])

HSP 1 Score: 301.212 bits (770), Expect = 7.348e-101
Identity = 140/287 (48.78%), Postives = 200/287 (69.69%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDI---ILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFA 912
            F ++EKIGEGTYG+VYK+ NK+T +  A+KKIR + + +G+  T +REIS+LKEL+HPNI+ L   +  + KLY+VFE+L  DL+R++D+  +P +++   ++K +  Q+++G+ +CH+ R +HRDLKPQNLL+D     IKLADFGLAR +G P++  THEVVTLWYRAPE++L +K YS A+D+ S+ CI AEM+T K LF GDSEIDQLF IF+ LGTP    WP + + P +   FP W       +V  +     DLL ++L Y P +R + + AL H YF+
Sbjct:    4 FQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQDLKRHMDS--SPTSELPLPVVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLD-GLGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYSTAVDI*SIGCIFAEMVTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGVSQMPDYQSSFPKWSRKGLEEIVPSLGPEGKDLLLRLLQYDPSQRISAKTALAHPYFS 287          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Match: Cdk2 (cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:MGI:104772])

HSP 1 Score: 298.516 bits (763), Expect = 3.637e-99
Identity = 152/342 (44.44%), Postives = 208/342 (60.82%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDI---ILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEM------------------------------------------------ITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+L+ DL++++D   + +  I   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++     IKLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEM                                                +T + LF GDSEIDQLF IF+ LGTPD  VWP +   P + P FP W     S++V  +DE+   LL +ML Y P +R + + AL H +F D+ K
Sbjct:    1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGS-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSAPHPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 339          
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|P51958|CDK1_CARAU (Cyclin-dependent kinase 1 OS=Carassius auratus OX=7957 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 365.155 bits (936), Expect = 4.532e-125
Identity = 171/302 (56.62%), Postives = 229/302 (75.83%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENP--MNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  NK T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+  +   M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWPD++  P +   FP W+    +  V+ +D+N  DLL KML+Y P +R + R A+ H YF DLDKS LPA +L+
Sbjct:    1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKSGNLASTVKNLDKNGIDLLTKMLIYDPPKRISARQAMTHPYFDDLDKSTLPASNLK 301          
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DG98|CDK1_ORYLU (Cyclin-dependent kinase 1 OS=Oryzias luzonensis OX=104659 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 5.529e-122
Identity = 164/299 (54.85%), Postives = 225/299 (75.25%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPAC 942
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +RE+S+L+EL+HPN+V L   + ++ +LYL+FE+L+MDL++YLD+      M+ +++K + YQI++G+ +CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS   I AE+ T KPLF GDSEIDQLF IF+ LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y+P +R + R+A+ H YF DLDKS LPA 
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKGGSLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPAA 298          
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DGD3|CDK1_ORYLA (Cyclin-dependent kinase 1 OS=Oryzias latipes OX=8090 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 6.033e-122
Identity = 164/299 (54.85%), Postives = 225/299 (75.25%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPAC 942
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +RE+S+L+EL+HPN+V L   + ++ +LYL+FE+L+MDL++YLD+      M+ +++K + YQI++G+ +CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS   I AE+ T KPLF GDSEIDQLF IF+ LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y+P +R + R+A+ H YF DLDKS LPA 
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKEGSLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPAA 298          
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|Q9DGA5|CDK1_ORYCU (Cyclin-dependent kinase 1 OS=Oryzias curvinotus OX=104658 GN=cdk1 PE=2 SV=1)

HSP 1 Score: 356.681 bits (914), Expect = 7.926e-122
Identity = 163/299 (54.52%), Postives = 225/299 (75.25%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPAC 942
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +RE+S+L+EL+HPN+V L   + ++ +LYL+FE+L+MDL++YLD+      M+ +++K + YQI++G+ +CH RR +HRDLKPQNLL+D NK +IKLADFGL+R +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS   I AE+ T KPLF GDSEIDQLF IF+ LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y+P +R + R+A+ H YF DLDKS LPA 
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLID-NKGVIKLADFGLSRAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKSTFPKWKGGSLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPAA 298          
BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Match: sp|P24033|CDK1B_XENLA (Cyclin-dependent kinase 1-B OS=Xenopus laevis OX=8355 GN=cdk1-b PE=1 SV=2)

HSP 1 Score: 356.295 bits (913), Expect = 1.380e-121
Identity = 169/298 (56.71%), Postives = 225/298 (75.50%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA 939
            + ++T+IEKIGEGTYG+VYK  +K T +  A+KKIR EN+E+G+  T +REIS+LKEL+HPNIV L   + +  +LYL+FE+L+MDL++YLD+      ++ +++K + YQI+QG+++CH+RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRA EV+L + RYS  +DVWSV  I AE+ T KPLF GDSEIDQLF IF+ LGTP+N+VWP+++    +   FP W+    S  V+ IDE+  DLL KMLVY P +R + R A+LH YF DLDKS LPA
Sbjct:    1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPEVESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDLDKSSLPA 297          
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A095BXJ3 (Cyclin-dependent kinase 1 OS=Schistosoma haematobium OX=6185 GN=MS3_01917 PE=3 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 2.266e-130
Identity = 183/309 (59.22%), Postives = 233/309 (75.40%), Query Frame = 1
Query:   43 SYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNE--ENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN-PLFPVWR---YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            +Y LSDF R+EKIGEGTYG+VYK  NK+  +FAA+KKIR ENDE+G+  T +REIS+LKEL+HPNIV L+Q I E G+LYLVFEYLN+DL+RYLD+   +N +   I+K F YQ++QGLL+CH RR +HRDLKPQN+LVD  + I+KLADFGLAR +G PV+ LTHEVVTLWYRAPE++L A+RYSCA+D+WS+ CI +E+ T + LFRGDSEIDQLF IF++LGTP  +VWP +   P +    FPVWR     ++  + +       DLL+ ML+Y P  R   RDALLH YF+DLDKS +PA   E
Sbjct:    6 NYALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHEVVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPVWRNSKLSIQDNIAKAFTSPGLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEE 314          
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: G4VLX9 (Serine/threonine kinase OS=Schistosoma mansoni OX=6183 GN=Smp_080730 PE=3 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 2.446e-130
Identity = 182/309 (58.90%), Postives = 233/309 (75.40%), Query Frame = 1
Query:   43 SYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNE--ENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN-PLFPVWR---YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            +Y LSDF R+EKIGEGTYG+VYK  NK+  +FAA+KKIR ENDE+G+  T +REIS+LKEL+HPNIV L+Q I E G+LYLVFEYLN+DL+RYLD+   +N +   I+K F YQ++QGLL+CH RR +HRDLKPQN+LVD  + I+KLADFGLAR +G PV+ LTHEVVTLWYRAPE++L A+RYSCA+D+WS+ CI +E+ T + LFRGDSEIDQLF IF++LGTP  +VWP +   P +    FP+WR     ++  + +       DLL+ ML+Y P  R   RDALLH YF+DLDKS +PA   E
Sbjct:    6 NYALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHEVVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFSSPGLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEE 314          
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183K468 (Protein kinase domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS9786 PE=3 SV=1)

HSP 1 Score: 388.267 bits (996), Expect = 3.505e-130
Identity = 182/309 (58.90%), Postives = 233/309 (75.40%), Query Frame = 1
Query:   43 SYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNE--ENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN-PLFPVWR---YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            +Y LSDF R+EKIGEGTYG+VYK  NK+  +FAA+KKIR ENDE+G+  T +REIS+LKEL+HPNIV L+Q I E G+LYLVFEYLN+DL+RYLD+   +N +   I+K F YQ++QGLL+CH RR +HRDLKPQN+LVD  + I+KLADFGLAR +G PV+ LTHEVVTLWYRAPE++L A+RYSCA+D+WS+ CI +E+ T + LFRGDSEIDQLF IF++LGTP  +VWP +   P +    FP+WR     ++  + +       DLL+ ML+Y P  R   RDALLH YF+DLDKS +PA   E
Sbjct:    6 NYALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHEVVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSPGLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEE 314          
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183NHN0 (Protein kinase domain-containing protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS1616 PE=3 SV=1)

HSP 1 Score: 388.267 bits (996), Expect = 3.505e-130
Identity = 182/309 (58.90%), Postives = 233/309 (75.40%), Query Frame = 1
Query:   43 SYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNE--ENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN-PLFPVWR---YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            +Y LSDF R+EKIGEGTYG+VYK  NK+  +FAA+KKIR ENDE+G+  T +REIS+LKEL+HPNIV L+Q I E G+LYLVFEYLN+DL+RYLD+   +N +   I+K F YQ++QGLL+CH RR +HRDLKPQN+LVD  + I+KLADFGLAR +G PV+ LTHEVVTLWYRAPE++L A+RYSCA+D+WS+ CI +E+ T + LFRGDSEIDQLF IF++LGTP  +VWP +   P +    FP+WR     ++  + +       DLL+ ML+Y P  R   RDALLH YF+DLDKS +PA   E
Sbjct:    6 NYALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNLDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHEVVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSPGLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEE 314          
BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Match: A0A183LHM5 (Protein kinase domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS3300 PE=3 SV=1)

HSP 1 Score: 387.882 bits (995), Expect = 4.914e-130
Identity = 182/309 (58.90%), Postives = 233/309 (75.40%), Query Frame = 1
Query:   43 SYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNE--ENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWN-PLFPVWR---YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            +Y LSDF R+EKIGEGTYG+VYK  NK+  +FAA+KKIR ENDE+G+  T +REIS+LKEL+HPNIV L+Q I E G+LYLVFEYLN+DL+RYLD+   +N +   I+K F YQ++QGLL+CH RR +HRDLKPQN+LVD  + I+KLADFGLAR +G PV+ LTHEVVTLWYRAPE++L A+RYSCA+D+WS+ CI +E+ T + LFRGDSEIDQLF IF++LGTP  +VWP +   P +    FP+WR     ++  + +       DLL+ ML+Y P  R   RDALLH YF+DLDKS +PA   E
Sbjct:    6 NYALSDFIRLEKIGEGTYGVVYKCKNKVNGKFAALKKIRLENDEEGVPSTAIREISLLKELQHPNIVNLEQVIMENGRLYLVFEYLNVDLKRYLDDSGRKNLLEPGIVKSFMYQMLQGLLFCHGRRVIHRDLKPQNILVDIGRKIVKLADFGLARAFGIPVRVLTHEVVTLWYRAPEILLGAQRYSCAVDIWSMGCIFSEVSTKEALFRGDSEIDQLFRIFRLLGTPSEEVWPGVSSLPEYQKKSFPIWRNSKLSIQDNIAKAFTSPGLDLLQAMLIYEPSRRITARDALLHPYFSDLDKSLVPATGEE 314          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 365.925 bits (938), Expect = 2.448e-126
Identity = 171/302 (56.62%), Postives = 230/302 (76.16%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+      M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF++LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y PL+R + R A+ H YF DLDK+ LPA +L+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKNLDKNGIDLLGKMLIYDPLKRISARQAMTHPYFDDLDKTTLPANNLK 301          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 365.925 bits (938), Expect = 2.448e-126
Identity = 171/302 (56.62%), Postives = 230/302 (76.16%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+      M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF++LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y PL+R + R A+ H YF DLDK+ LPA +L+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKNLDKNGIDLLGKMLIYDPLKRISARQAMTHPYFDDLDKTTLPANNLK 301          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 328.946 bits (842), Expect = 7.558e-112
Identity = 162/303 (53.47%), Postives = 219/303 (72.28%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQ-GLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLE 951
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+      M+ +++   +  +   G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF++LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DL     V + L R + R A+ H YF DLDK+ LPA +L+
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVDLINLCVSSCGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKNLDKNGIDLSN---VLNLLCRISARQAMTHPYFDDLDKTTLPANNLK 299          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:103047431])

HSP 1 Score: 326.635 bits (836), Expect = 4.197e-111
Identity = 151/265 (56.98%), Postives = 203/265 (76.60%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLL 840
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +REIS+LKEL+HPN+V L   + ++ KLYLVFE+L+MDL++YLD+      M+ +++K + YQI++G+L+CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L A RYS  +DVWS+  I AE+ T KPLF GDSEIDQLF IF++LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL
Sbjct:    1 MEDYMKIEKIGEGTYGVVYKGRHKSTGQVVALKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRILGTPNNDVWPDVESLPDYKNTFPKWKTGNLSSMVKNLDKNGIDLL 264          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:103028318])

HSP 1 Score: 325.094 bits (832), Expect = 2.881e-110
Identity = 152/290 (52.41%), Postives = 209/290 (72.07%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  F ++EKIGEGTYG+VYK+ NKIT E  A+KKIR + + +G+  T +REIS+LKEL HPNIV L   I  + KLYLVFE+L+ DL++++D+     ++  ++K + +Q++QGL +CH+ R +HRDLKPQNLL++    I KLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+D+WS+ CI AEMIT + LF GDSEIDQLF IF+ LGTPD  VWP +   P + P FP W     +++V  +DE+  DLL +ML Y P +R + ++AL+H +F D+
Sbjct:    4 MESFQKVEKIGEGTYGVVYKAKNKITGETVALKKIRLDTETEGVPSTAIREISLLKELSHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETVWPGVTSMPDYKPSFPKWALQDLAKVVPPLDEDGRDLLGQMLNYDPNKRISAKNALVHRFFRDV 292          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1])

HSP 1 Score: 313.538 bits (802), Expect = 1.080e-106
Identity = 152/287 (52.96%), Postives = 204/287 (71.08%), Query Frame = 1
Query:   88 GTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSY--QIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLP 936
            G+YG+VYK  NK T +  A+KKIR E++E+G+  T +REI++L+ELRHPNIV LQ  + +  +LYL+FEYL MDL+RYLD     + M   +++  SY  QI+Q +++CH+RR +HRDLKPQNLL+D + HI KLADFGLAR +G PV+  THEVVTLWYRAPEV+L   RYS  +D+WSV  I+AEM+  +PLF GDSEIDQLF IF++LGTP  +VWPD+   P + P FP W        V  ++++  DLLEKML Y P  R + + AL H YF + ++S +P
Sbjct:    1 GSYGVVYKGRNKGTGDLVALKKIRLEHEEEGVPATAIREIALLRELRHPNIVRLQDVLLQSARLYLIFEYLPMDLKRYLDAIPAGHCMEPPLIQGQSYLHQILQAVVFCHSRRVLHRDLKPQNLLIDRHGHI-KLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGTPRYSTPVDMWSVGTILAEMVNKRPLFHGDSEIDQLFRIFRILGTPTTEVWPDVVTLPDYKPSFPKWVPSGLVAHVPGLNQDGIDLLEKMLTYDPARRISAKRALTHPYFQN-EESAVP 285          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 310.457 bits (794), Expect = 2.590e-105
Identity = 145/288 (50.35%), Postives = 206/288 (71.53%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEEN-PMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLD 921
            F ++EKIGEGTYG+VYK+ +K+T +  A+KKIR + + +G+  T +REI++L+EL HPNIV L   I  + KLYLVFE+L+ DL++Y+DN     ++  ++K + +Q++QG+ +CH +R +HRDLKPQNLL++ +   IKLADFGLAR +G P++  THEVVTLWYRAPE++L  K YS A+DVWS+ CI AEM+T + LF GDSEIDQLF IF+ LGTPD  VW  + + P + P FP W     +++V ++D    DLL +ML Y P  R + + AL H +F +L+
Sbjct:    4 FQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHSETKLYLVFEFLDQDLKKYMDNAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINADG-AIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDETVWQGITQLPDYKPSFPRWCAQDLTKVVPLLDAAGHDLLMQMLQYDPTRRVSAKAALNHHFFHNLE 290          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741])

HSP 1 Score: 307.375 bits (786), Expect = 4.895e-104
Identity = 145/292 (49.66%), Postives = 202/292 (69.18%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDI-ILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDK 924
            + +F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+L+EL HPNIV L   I  + KLYLVFE L+ DL++++DN       + ++K + YQ++QG+ +CH+ R +HRDLKPQNLL++  +  IKLADFGLAR +G P +  THEVVTLWYRAPE++L  K YS ++DVWS+ CI AEM+T + LF GDSEIDQLF IF+ LGTPD  VWP + + P +   FP W     +++V  ++    DLL  ML Y P +R     AL H +F ++ +
Sbjct:    1 MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINA-EGAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKSTFPRWANQELTKVVPTLNFEGRDLLALMLQYDPNQRVTANMALSHCFFQNVKQ 291          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008013.1 (pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 gene:ENSPMAG00000007231.1 transcript:ENSPMAT00000008013.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 246.128 bits (627), Expect = 1.061e-77
Identity = 128/290 (44.14%), Postives = 185/290 (63.79%), Query Frame = 1
Query:   49 QLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDL---DKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 909
            +L  +T+++K+GEGTY  VYK  +K+T+   A+K+IR E++E G   T +RE+S+LK+L+H NIV L   +     L LVFEYL  DL++Y+D+  N M+   +K F  Q+++GL YCH RR +HRDLKPQNLL++ +K  +KLADFGLAR    P K  ++EVVTLWYR P+V+L +  YS  ID+W V CI  EM   +PLF G +  D+L  IF++LG+P   +WP +   +++  +N  FP +R +        +D +  DLL K L+Y    R +  DAL   YF
Sbjct:  194 KLETYTKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHEE-GAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLEKDLKQYMDDCGNIMSMHNVKIFLLQLLRGLAYCHKRRVLHRDLKPQNLLIN-DKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTQIDMWGVGCIFFEMAAGRPLFPGSTVEDELHLIFRMLGSPREDMWPGISSNEEYKSYN--FPKYRSEPMITHAPRLDVDGLDLLSKFLLYEAKARISAEDALKRPYF 479          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Match: cdk7 (cyclin-dependent kinase 7 [Source:ZFIN;Acc:ZDB-GENE-010320-2])

HSP 1 Score: 223.402 bits (568), Expect = 1.503e-70
Identity = 110/296 (37.16%), Postives = 173/296 (58.45%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIR---SENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA 939
            + +I+ +GEG +  VYK+++K+TN+  AIKKI+       +DGI  T LREI +L+EL HPNI+ L      K  + LVF++++ DL   + +    ++   +K F    +QGL Y H    +HRD+KP NLL+D  + ++KLADFGLA+ +G+P +  TH+VVT WYR+PE++  A+ Y   +D+W+V CI+AE++   P   GDS++DQL  IF+ LGTP  ++WP +   P +          L +      D +L +LL+ +  + P  R     A+   YF++      PA
Sbjct:   26 YDKIDFLGEGQFATVYKAMDKVTNKIVAIKKIKLGHRTEAKDGINRTALREIKLLQELNHPNIIGLLDAFGHKSNISLVFDFMDTDLEVIVKDTSLVLSPANIKSFMVMTLQGLEYLHMHWILHRDMKPNNLLLD-EQGVLKLADFGLAKSFGSPSRVYTHQVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRTPFLPGDSDLDQLSKIFEALGTPTEELWPGMTNLPDYVEYKSFPGTPLENIFTAATD-DLLELLQGLFTFSPAARLTATQAMQMPYFSNRPGPTPPA 319          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364])

HSP 1 Score: 311.997 bits (798), Expect = 3.766e-106
Identity = 146/298 (48.99%), Postives = 212/298 (71.14%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSIN---KITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTI-AEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            MS +L+++ R+EK+GEGTYG+VYK+++          A+KKIR E++++G+  T +REIS+LKEL+  NIV L   + ++  KLYLVFE+L++DL+RY++   ++ P+   I+KKF  Q+ +G+ YCH+ R +HRDLKPQNLL++ + ++ KL DFGLAR +G P++  THE+VTLWYRAPEV+L  K+YS  +D WS+ CI AEM   KP+F GDSEIDQ+F IF+VLGTP+  +WPD+   P + P FP WR    S++V  +D    DLL+K+L Y P+ R + R A +H YF +
Sbjct:    1 MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNL-KLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE 297          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 263.077 bits (671), Expect = 6.870e-87
Identity = 130/297 (43.77%), Postives = 192/297 (64.65%), Query Frame = 1
Query:   55 SDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLD-----NEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPV-----WRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            S F ++EK+G GTY  VYK +NK T  + A+K+++ +++E G   T +REIS++KEL+H NIV L   I  + KL LVFE+++ DL++Y+D     N    +   ++K F +Q++QGL +CH  + +HRDLKPQNLL++    + KL DFGLAR +G PV   + EVVTLWYRAP+V++ ++ YS +ID+WS  CI+AEMIT KPLF G ++ +QL  IF ++GTP+  +WP + K P +NP          R  L+    E +D NL D L  +L  +P  R + + AL H +FA+
Sbjct:    5 SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEE-GTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQL-KLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAE 299          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: KIN28 (Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266])

HSP 1 Score: 201.445 bits (511), Expect = 8.768e-63
Identity = 109/298 (36.58%), Postives = 165/298 (55.37%), Query Frame = 1
Query:   58 DFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLF---PVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPAC 942
            ++T+ +K+GEGTY +VY      T    AIK+I++   +DG+  + +RE+  L+E++HPN++ L         L LV E+L  DL   + ++        +K +    ++G+ +CH    +HRDLKP NLL   +  I K+ADFGLAR   AP + LT  VVT WYRAPE++  AK Y+ AID+WSV  I AE++   P   G +++DQ+   F+ LGTP ++ WP++  F  +N L    P  R +LR R +    E   D +  ML  +P +R      L  DYF +L     P+ 
Sbjct:    6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQI-KVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAA-SEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPSS 301          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: CTK1 (Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622])

HSP 1 Score: 186.422 bits (472), Expect = 9.809e-55
Identity = 100/298 (33.56%), Postives = 169/298 (56.71%), Query Frame = 1
Query:   55 SDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGK-LYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFP--VWRY--DLRSRLVEVI-DENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSD 930
            S + RI ++GEGTYG VYK+ N  T +  A+KK+R + + +G   T++REI +L+   HPN+  +++ + E  K +Y++FEY + DL   L N+E  ++    K    Q++ G+ Y H  + +HRD+K  N+L+D N+  +K+ DFGLAR   +   + T+ V+TLWYR PE++L    Y   +D+W   C++ E+     +F+G +E++Q+ +IFK++GTP    WP L   P +  + P    +Y  +   +   V+       L   +L Y   +R +  +AL  DYF +  K +
Sbjct:  181 SVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILID-NQGNLKITDFGLARKMNSRA-DYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFKEEPKPE 476          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Match: SGV1 (Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365])

HSP 1 Score: 186.422 bits (472), Expect = 5.831e-54
Identity = 111/306 (36.27%), Postives = 158/306 (51.63%), Query Frame = 1
Query:   73 EKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKG-------------KLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNL------------THEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            EK+G+GT+G VYK I+  T    A+KKI    ++D    T  REI+ILK L H NI+ L + + +                 Y++  Y+  DL   L N    +    +K    QI++GL Y H  +FMHRD+K  N+L+D N  ++KLADFGLAR Y     NL            T  VVT WYRAPE++L  K+Y+ A+D+W V C+ AE    KP+ +G ++IDQ   IFK+LGTP  + W      PG       ++  LR R  + + E   D L ++L   P +R     A  H +F +
Sbjct:   64 EKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNG-VLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKE 368          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO43671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXS1])

HSP 1 Score: 334.724 bits (857), Expect = 1.953e-114
Identity = 159/295 (53.90%), Postives = 210/295 (71.19%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRH-PNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDL 933
            + DF++IEKIGEGTYG+VYK+ N  T  FAA+KKIR E +++GI  T +REIS+LKELRH PN+V LQ  + ++ KLYLVFEYL  DL+++LD     ++  ++K + YQI   + +CH RR +HRDLKPQNLL+D+ K +IKLADFGL R +G PV+  THEVVTLWYRAPEV+L  +RYSC IDVWS+  I AEM+T +PLF GDSEIDQLF IF++LGTP  + W  +   P + P FP W  D   + V  +D +  DLL+KML+Y P  R + + +L H YF +  K D+
Sbjct:    1 MDDFSKIEKIGEGTYGVVYKAKNLKTGGFAALKKIRLEVEDEGIPSTAVREISLLKELRHHPNVVELQHILHQEPKLYLVFEYLTCDLKKHLDTTRGMLDKTLVKSYLYQITNAIYFCHARRILHRDLKPQNLLIDS-KGLIKLADFGLGRAFGIPVRAYTHEVVTLWYRAPEVLLGGQRYSCPIDVWSIGTIFAEMVTKRPLFHGDSEIDQLFRIFRILGTPTEETWKGVTSLPDYKPTFPKWAGDGLKKAVPQLDSDGLDLLKKMLIYDPALRISAKTSLKHPYFLNDPKFDI 294          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0])

HSP 1 Score: 319.701 bits (818), Expect = 9.845e-109
Identity = 146/295 (49.49%), Postives = 206/295 (69.83%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN-EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDL 933
            + +F ++EKIGEGTYG+VYK+ +K T    A+KKIR + + +G+  T +REIS+LKEL HPN+V L   +  +  LYLVFE+L+ DL++Y+D    + ++  ++K + YQ++ G+ YCH+ R +HRDLKPQNLL+D N   IKLADFGLAR +G PV++ THEVVTLWYRAPE++L ++ Y+  +DVWS+ CI AEM T + LF GDSEIDQLF IF+ LGTPD+KVWP + + P +   FP W       ++  +D    DLL+KML Y P  R + + AL H++F D+ +  L
Sbjct:    1 MENFEKVEKIGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDVVHNQKSLYLVFEFLSQDLKKYMDCLPPSGISTSLIKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDKNG-AIKLADFGLARAFGVPVRSYTHEVVTLWYRAPEILLGSRYYATPVDVWSIGCIFAEMKTRRALFPGDSEIDQLFRIFRTLGTPDDKVWPGVSELPDYKTSFPKWPVQSIRHVLPTLDNTAIDLLQKMLTYQPNARISAKAALSHEFFKDVQRKIL 294          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO49420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF7])

HSP 1 Score: 271.552 bits (693), Expect = 7.062e-90
Identity = 131/293 (44.71%), Postives = 193/293 (65.87%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMIT-YKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKS 927
            +  + ++EKIGEGTYG V+K  NK T E  A+K++R ++D++G+  + LREI +LKEL+H NIV L   +  + KL LVFE+ + DL++Y D+ +  ++  ++K F +Q+++GL +CH+   +HRDLKPQNLL++ +   +KLADFGLAR +G PV+  + EVVTLWYR P+V++ AK YS +ID+WS  CI AEM    +PLF G+   DQL  IFK+LGTP  + WP++ K P +    P         +V  +     DLL+K+LV +P  R +  DA+ H YFADL  +
Sbjct:    1 MQKYDKLEKIGEGTYGTVFKGKNKETREILALKRVRLDDDDEGVPSSALREICLLKELKHNNIVRLYDVLHSEKKLTLVFEFCDQDLKKYFDSCQGEVDASVVKSFMFQLLRGLAFCHSHNVLHRDLKPQNLLINKDGE-LKLADFGLARAFGIPVRCFSAEVVTLWYRPPDVLMGAKLYSTSIDMWSAGCIFAEMANGGRPLFPGNDVDDQLRRIFKILGTPTEESWPNVSKLPDYKEFPPQGPSVSLGMVVPKLSSTGRDLLQKLLVSNPAHRISAEDAMKHAYFADLSPT 292          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO48117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK70])

HSP 1 Score: 253.062 bits (645), Expect = 3.700e-82
Identity = 136/312 (43.59%), Postives = 195/312 (62.50%), Query Frame = 1
Query:   49 QLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDK----FPGWNPLFPVWRYDLRSRLV---EVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYS 963
            ++  +T+++K+GEGTY  V+K  +K+T+   A+K+IR E++E G   T +RE+S+LK L+H NIV L  T+  +  L LVFEYL  DL++Y+D+    M+   ++ F +Q+++GL YCH R+ +HRDLKPQNLL++ +K  +KLADFGLAR    P K  ++EVVTLWYR P+V+L +  YS  ID+W V CI  EM T +PLF G +  D+L  IFKVLGTP  +VWP +        G  P +P      R  L+     +D +  +LLEK L Y   +R +  DA+ HDYF  L    L   DL+  +S
Sbjct:    7 KMETYTKLDKLGEGTYATVFKGKSKLTDNIVALKEIRLEHEE-GAPCTAIREVSLLKGLKHANIVTLHDTVHTQKSLTLVFEYLEKDLKQYMDDCGGIMSMNNVRIFLFQLLRGLDYCHKRKVLHRDLKPQNLLIN-DKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTAYSTQIDMWGVGCIFFEMATGRPLFPGSTVEDELLLIFKVLGTPSEEVWPGISANEAFIAGKFPDYP------RENLIIHAPRLDNSGLELLEKFLEYTVKDRVSAHDAMRHDYFYSLGTRCLNLGDLDSLFS 310          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Match: EDO46173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQW1])

HSP 1 Score: 234.958 bits (598), Expect = 1.916e-75
Identity = 127/297 (42.76%), Postives = 181/297 (60.94%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEK----------GKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKN-LTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSR-LVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            F  IE+IGEGTYG VYK+ +KIT E   +KK+R++N+++G   T +REI IL +L HPNI+ L++ + +K          G  YLVFEY++ DL   L++    + +  +K F  Q++ GL YCH + F+HRD+K  N+L++ NK  IKLADFGLAR Y A  +   T++V+TLWYR PE++L  +RY   ID+WSV CI+AE+ T KP+F    EI QL  I +V GTP   VWP +   P ++ + P  +Y  R R     + E+  DL + ML   P +R     AL H +  D
Sbjct:    2 FDIIEQIGEGTYGQVYKAKDKITGELVGLKKVRTDNEKEGFPITAVREIKILCQLNHPNIINLKEIVTDKPNALDFRKDKGAFYLVFEYMDHDLMGLLESGLVHLTEDHIKSFIRQLLDGLNYCHKKNFLHRDIKCSNILLN-NKGEIKLADFGLARLYEADERRPYTNKVITLWYRPPELLLGEERYGPGIDIWSVGCILAELFTKKPIFPAYQEIGQLELISRVCGTPTPAVWPSIINLPHFHSIKPKRQYRRRIREEFNFLPEDALDLFDAMLTLDPSQRITAEKALEHPFLTD 297          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk1 (cyclin dependent kinase 1 [Source:NCBI gene;Acc:100049478])

HSP 1 Score: 357.066 bits (915), Expect = 6.731e-123
Identity = 164/299 (54.85%), Postives = 225/299 (75.25%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDN--EENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPAC 942
            + D+ +IEKIGEGTYG+VYK  +K T +  A+KKIR E++E+G+  T +RE+S+L+EL+HPN+V L   + ++ +LYL+FE+L+MDL++YLD+      M+ +++K + YQI++G+ +CH RR +HRDLKPQNLL+D NK +IKLADFGLAR +G PV+  THEVVTLWYRAPEV+L + RYS  +DVWS   I AE+ T KPLF GDSEIDQLF IF+ LGTP+N VWPD++  P +   FP W+    S +V+ +D+N  DLL KML+Y+P +R + R+A+ H YF DLDKS LPA 
Sbjct:    1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLID-NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWKEGSLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPAA 298          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:101161880])

HSP 1 Score: 325.865 bits (834), Expect = 1.094e-110
Identity = 152/290 (52.41%), Postives = 209/290 (72.07%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV LQ  I  + KLYLVFE+L+ DL++++D+     +   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++    I KLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+DVWS+ CI AEMIT + LF GDSEIDQLF IF+ LGTPD   WP +   P + P FP W     S++V ++DE+  +LL +ML Y P +R + ++AL+H +F D+
Sbjct:    1 MDTFQKVEKIGEGTYGVVYKAKNKLTGETVALKKIRLDTETEGVPSTAIREISLLKELSHPNIVKLQDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGIPLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETAWPGVTSMPDYKPSFPKWARQDLSKVVPLLDEDGRELLGEMLKYDPNKRLSAKNALVHRFFRDV 289          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:101161880])

HSP 1 Score: 279.256 bits (713), Expect = 8.378e-93
Identity = 137/290 (47.24%), Postives = 189/290 (65.17%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR +                           LQ  I  + KLYLVFE+L+ DL++++D+     +   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++    I KLADFGLAR +G PV+  THEVVTLWYRAPE++L  K YS A+DVWS+ CI AEMIT + LF GDSEIDQLF IF+ LGTPD   WP +   P + P FP W     S++V ++DE+  +LL +ML Y P +R + ++AL+H +F D+
Sbjct:    1 MDTFQKVEKIGEGTYGVVYKAKNKLTGETVALKKIRLDT--------------------------LQDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGIPLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDETAWPGVTSMPDYKPSFPKWARQDLSKVVPLLDEDGRELLGEMLKYDPNKRLSAKNALVHRFFRDV 263          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk5 (cyclin dependent kinase 5 [Source:NCBI gene;Acc:101174461])

HSP 1 Score: 268.085 bits (684), Expect = 4.335e-88
Identity = 133/293 (45.39%), Postives = 195/293 (66.55%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITY-KPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVI---DENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  + ++EKIGEGTYG V+K+ N+ T+E  A+K++R ++D++G+  + LREI +LKEL+H NIV L   +    KL LVFEY + DL++Y D+    ++   +K F YQ+++GL +CH+R  +HRDLKPQNLL++ N   +KLADFGLAR +G PV+  + EVVTLWYR P+V+  AK YS +ID+WS  CI AE+    +PLF G+   DQL  IF++LGTP  + WP + K P + P +P+  Y   + LV V+        DLL+ +L  +P++R +  +AL H YFAD 
Sbjct:    1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPETVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGE-LKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPTMTKLPDYKP-YPM--YPATTSLVNVVPKLSNTGRDLLQNLLKCNPVQRISAEEALQHPYFADF 289          
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Match: cdk2 (cyclin dependent kinase 2 [Source:NCBI gene;Acc:101161880])

HSP 1 Score: 254.218 bits (648), Expect = 4.357e-83
Identity = 131/291 (45.02%), Postives = 184/291 (63.23%), Query Frame = 1
Query:   52 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEE-NPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVW-RYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADL 918
            +  F ++EKIGEGTYG+VYK+ NK+T E  A+KKIR + + +G+  T +REIS+LKEL HPNIV LQ  I  + KLYLVFE+L+ DL++++D+     +   ++K + +Q++QGL +CH+ R +HRDLKPQNLL++     IKLADFGLAR +G PV+  THE                                  IT + LF GDSEIDQLF IF+ LGTPD   WP +   P + P FP W R DL S++V ++DE+  +LL +ML Y P +R + ++AL+H +F D+
Sbjct:    1 MDTFQKVEKIGEGTYGVVYKAKNKLTGETVALKKIRLDTETEGVPSTAIREISLLKELSHPNIVKLQDVIHTENKLYLVFEFLHQDLKKFMDSSSVTGIPLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-IKLADFGLARAFGVPVRTYTHE----------------------------------ITRRALFPGDSEIDQLFRIFRTLGTPDETAWPGVTSMPDYKPSFPKWARQDL-SKVVPLLDEDGRELLGEMLKYDPNKRLSAKNALVHRFFRDV 255          
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000052413.1 (SMESG000052413.1)

HSP 1 Score: 682.945 bits (1761), Expect = 0.000e+0
Identity = 330/330 (100.00%), Postives = 330/330 (100.00%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYSDSINKFYQVSKCDPLVDKSNIQ 1029
            MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYSDSINKFYQVSKCDPLVDKSNIQ
Sbjct:    1 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYSDSINKFYQVSKCDPLVDKSNIQ 330          
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000052421.1 (SMESG000052421.1)

HSP 1 Score: 407.142 bits (1045), Expect = 4.107e-142
Identity = 191/309 (61.81%), Postives = 237/309 (76.70%), Query Frame = 1
Query:   40 MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYD-LRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERKYS 963
            + + +SDF +IEKIGEGTYG+VYK  NK T +FAA+KKIR ENDEDG+  T +REIS+LKEL HPNIV L+Q++ + GKL+LVFEYLNMDLRRYLDN +  M+ +++K F YQI+QGLL+CH RR +HRDLKPQNLLVD    IIKLADFGLAR +G PVK LTHEVVTLWYRAPE+++ +KRYSCA+DVWSVACI AEM T KPLFRGDSEIDQ+F IF +LGTP    WP +     WN + P+W    L S   + +  +  DL+ +ML+Y+P +R N RDALLH YFA+L++S LPA   E + S
Sbjct:    8 VKFSISDFIKIEKIGEGTYGVVYKGKNKKTGDFAALKKIRLENDEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLARTFGVPVKALTHEVVTLWYRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWPGVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYFANLNRSQLPAHGEEHRAS 316          
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000074437.1 (SMESG000074437.1)

HSP 1 Score: 284.263 bits (726), Expect = 1.372e-94
Identity = 141/273 (51.65%), Postives = 191/273 (69.96%), Query Frame = 1
Query:  145 IKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPD-NKVWPDLDKFPGWNPLFPVWR-YDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPACDLERK 957
            +K+I+ + +E GI  TTLREISILK L+HPNIV L++ I    KLY+VFE+++MDL+ +    +  +N  I++   YQ++QGLLYCH RR +HRDLKPQN+LV+    ++KLADFGL R YG P K +T E++T WYRAPE+IL AK Y+C++D+WSV CI AE+    PLF GDSEI QLF IF++ GTPD N ++  L+K   W  +FP W    L  ++   + +   DLL K+LVY+PLER N +D LLHDYF D DK+ +PA + E K
Sbjct:    3 LKRIKLDGNE-GIQCTTLREISILKNLQHPNIVSLEKVILLPNKLYMVFEFIDMDLQAFALRLDTGLNSEIIRSIMYQLLQGLLYCHKRRVIHRDLKPQNILVNKTGTLVKLADFGLGRIYGIPSKKMTTEIITQWYRAPEIILGAKTYNCSVDMWSVGCIFAELALGAPLFNGDSEIGQLFKIFQINGTPDANSIFIRLEK---WQDVFPNWTGTTLSVKMDGYLSKIGIDLLSKLLVYNPLERLNSQDTLLHDYFLDFDKTTVPASNEECK 271          
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000000804.1 (SMESG000000804.1)

HSP 1 Score: 259.225 bits (661), Expect = 1.078e-84
Identity = 134/289 (46.37%), Postives = 184/289 (63.67%), Query Frame = 1
Query:   61 FTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMIT-YKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFP-----GWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 909
            F ++EKIGEGTYG V+K+ N+ + E  A+K++R + D++GI  + LREI +LKEL+HPNIV L   +    +L +VFEY + DL++Y D+    ++   +K F YQ+++GL YCH+   +HRDLKPQNLL++ N   +KLADFGLAR +G PV+  + EVVTLWYR P+V+  AK YS  ID+WS  CI AEM    +PLF G+   DQL  IFK LGTP   +WP + + P      + P  P W     S+ V  +     DLL+K+LV  P +R N   AL H YF
Sbjct:    9 FEKLEKIGEGTYGTVFKAKNRESFEIVALKRVRLDEDDEGIPSSALREICLLKELKHPNIVKLIDVLLSDRRLTMVFEYCDQDLKKYFDSCNGEIDQNTVKSFMYQLLRGLHYCHSHNVLHRDLKPQNLLINDNGE-LKLADFGLARAFGIPVRQYSAEVVTLWYRPPDVLFGAKLYSTTIDMWSAGCIFAEMSNGGRPLFPGNDVDDQLKRIFKFLGTPTEDIWPGVTQLPEYKQFSYYPCNPNW-----SQGVPKLSSKGRDLLQKLLVCCPADRINSDLALSHVYF 291          
BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Match: SMESG000018037.1 (SMESG000018037.1)

HSP 1 Score: 254.218 bits (648), Expect = 1.815e-82
Identity = 136/308 (44.16%), Postives = 187/308 (60.71%), Query Frame = 1
Query:   49 QLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAPTTLREISILKELR---HPNIVYLQQTIAEKGKLYLVFEYLNMDLRRY-----------LDNEEN-----PMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFAD 915
            ++  + +   IG GTYG VYK+    +N+  AIK+I  +  EDGI  +T+REI IL E +   HPNIV+L + I   G++ +VFEY++ DL+R+           L N EN     P+N   +K  ++QIMQ LL+CH  +  HRD+KP NLL+ TN  +IKLADFGL+R Y  P +   HEVVTLWYRAPE++L    Y   ID+WS+ CI+ EMIT K LF GDSEIDQLF IFK  GTPD K WP +   P +   FP+++    S L   +  +  +L+  ML Y P  R+N+ + L + +  D
Sbjct:    2 RIGKYIKESIIGSGTYGTVYKAKEYGSNKLFAIKQINHDEVEDGIPASTIREIGILLEFKQQSHPNIVHLHEVIHRDGEISMVFEYIDYDLKRFHDEYSKVVNRCLKNNENSVVGLPIN--FVKNITHQIMQALLFCHQHKVFHRDIKPSNLLL-TNCGVIKLADFGLSRTYSFPNRTYCHEVVTLWYRAPEIMLGVSDYMIGIDIWSIGCIVTEMITGKILFPGDSEIDQLFLIFKRFGTPDEKCWPGVTSLPDYKSTFPMFKNRNLSDL--SLPNDAANLISTMLSYVPEGRSNLSNLLQYKFVRD 304          
The following BLAST results are available for this feature:
BLAST of Cyclin-dependent kinase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CDK17.676e-11854.79cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:... [more]
CDK15.177e-11754.11cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:... [more]
CDK25.081e-10952.04cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:... [more]
CDK32.005e-10148.97cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:... [more]
CDK32.005e-10148.97cyclin dependent kinase 3 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk-12.509e-11451.77Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss... [more]
cdk-12.509e-11451.77Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss... [more]
cdk-21.975e-9046.88Cyclin-dependent kinase 2 [Source:UniProtKB/Swiss... [more]
cdk-53.329e-8444.44Cyclin-dependent-like kinase 5 [Source:UniProtKB/... [more]
pct-12.576e-7142.71Cyclin-dependent kinase 17 [Source:UniProtKB/Swis... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdk11.090e-11050.69gene:FBgn0004106 transcript:FBtr0080051[more]
Cdk22.702e-9147.65gene:FBgn0004107 transcript:FBtr0083922[more]
Cdk22.702e-9147.65gene:FBgn0004107 transcript:FBtr0300447[more]
Cdk22.702e-9147.65gene:FBgn0004107 transcript:FBtr0083921[more]
Cdk57.999e-8443.29gene:FBgn0013762 transcript:FBtr0087350[more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk13.086e-12556.29cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk13.086e-12556.29cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk29.193e-11252.41cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk58.953e-8845.39cyclin-dependent kinase 5 [Source:ZFIN;Acc:ZDB-GEN... [more]
CDK181.758e-7742.53si:dkey-166c18.1 [Source:ZFIN;Acc:ZDB-GENE-141215-... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cfap658.467e-12256.04cilia and flagella associated protein 65 [Source:X... [more]
cfap652.124e-11455.79cilia and flagella associated protein 65 [Source:X... [more]
cfap654.438e-11455.79cilia and flagella associated protein 65 [Source:X... [more]
cdk25.900e-10650.68cyclin-dependent kinase 2 [Source:NCBI gene;Acc:49... [more]
cdk23.837e-10046.84cyclin-dependent kinase 2 [Source:NCBI gene;Acc:49... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cdk17.966e-11754.11cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:M... [more]
Cdk17.966e-11754.11cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:M... [more]
Cdk29.820e-10951.70cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:M... [more]
Cdk37.348e-10148.78cyclin-dependent kinase 3 [Source:MGI Symbol;Acc:M... [more]
Cdk23.637e-9944.44cyclin-dependent kinase 2 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Cyclin-dependent kinase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P51958|CDK1_CARAU4.532e-12556.62Cyclin-dependent kinase 1 OS=Carassius auratus OX=... [more]
sp|Q9DG98|CDK1_ORYLU5.529e-12254.85Cyclin-dependent kinase 1 OS=Oryzias luzonensis OX... [more]
sp|Q9DGD3|CDK1_ORYLA6.033e-12254.85Cyclin-dependent kinase 1 OS=Oryzias latipes OX=80... [more]
sp|Q9DGA5|CDK1_ORYCU7.926e-12254.52Cyclin-dependent kinase 1 OS=Oryzias curvinotus OX... [more]
sp|P24033|CDK1B_XENLA1.380e-12156.71Cyclin-dependent kinase 1-B OS=Xenopus laevis OX=8... [more]
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BLAST of Cyclin-dependent kinase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A095BXJ32.266e-13059.22Cyclin-dependent kinase 1 OS=Schistosoma haematobi... [more]
G4VLX92.446e-13058.90Serine/threonine kinase OS=Schistosoma mansoni OX=... [more]
A0A183K4683.505e-13058.90Protein kinase domain-containing protein OS=Schist... [more]
A0A183NHN03.505e-13058.90Protein kinase domain-containing protein OS=Schist... [more]
A0A183LHM54.914e-13058.90Protein kinase domain-containing protein OS=Schist... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk12.448e-12656.62cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk12.448e-12656.62cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk17.558e-11253.47cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk14.197e-11156.98cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk22.881e-11052.41cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk11.080e-10652.96cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk22.590e-10550.35cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
cdk24.895e-10449.66cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
ENSPMAT00000008013.11.061e-7744.14pep scaffold:Pmarinus_7.0:GL478839:10839:40406:1 g... [more]
cdk71.503e-7037.16cyclin-dependent kinase 7 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC283.766e-10648.99Cyclin-dependent kinase (CDK) catalytic subunit; m... [more]
PHO856.870e-8743.77Cyclin-dependent kinase; has ten cyclin partners; ... [more]
KIN288.768e-6336.58Serine/threonine protein kinase, subunit of transc... [more]
CTK19.809e-5533.56Catalytic (alpha) subunit of C-terminal domain kin... [more]
SGV15.831e-5436.27Cyclin (Bur2p)-dependent protein kinase; part of t... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO436711.953e-11453.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414039.845e-10949.49Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494207.062e-9044.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481173.700e-8243.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461731.916e-7542.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cdk16.731e-12354.85cyclin dependent kinase 1 [Source:NCBI gene;Acc:10... [more]
cdk21.094e-11052.41cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
cdk28.378e-9347.24cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
cdk54.335e-8845.39cyclin dependent kinase 5 [Source:NCBI gene;Acc:10... [more]
cdk24.357e-8345.02cyclin dependent kinase 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of Cyclin-dependent kinase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000052413.10.000e+0100.00SMESG000052413.1[more]
SMESG000052421.14.107e-14261.81SMESG000052421.1[more]
SMESG000074437.11.372e-9451.65SMESG000074437.1[more]
SMESG000000804.11.078e-8446.37SMESG000000804.1[more]
SMESG000018037.11.815e-8244.16SMESG000018037.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032688 ID=SMED30032688|Name=Cyclin-dependent kinase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1095bp
CCATTAATTTTAATTTTTGATAAAGGCTTAATCCATTAAATGTCCTATCA
ACTATCAGACTTCACTCGAATAGAAAAAATTGGTGAAGGAACTTATGGTA
TAGTTTATAAAAGTATCAATAAAATAACCAATGAATTTGCTGCTATTAAA
AAAATTCGATCGGAAAATGATGAGGATGGTATAGCTCCTACGACTCTAAG
AGAAATTTCAATTTTAAAAGAGCTTAGACATCCAAATATTGTTTATTTAC
AACAAACCATCGCTGAAAAAGGAAAATTATATTTAGTATTTGAATATCTA
AATATGGATTTACGCAGATATTTGGATAATGAGGAAAATCCAATGAATGA
TATTATACTAAAAAAATTTTCTTATCAAATTATGCAGGGCTTATTATATT
GTCATACTAGGCGTTTTATGCATCGAGATTTAAAACCTCAAAATTTACTA
GTTGACACTAACAAACATATTATTAAATTAGCGGATTTTGGCCTAGCTAG
ATGTTATGGGGCTCCCGTTAAGAATTTAACTCATGAGGTAGTTACATTAT
GGTATCGAGCTCCTGAAGTAATTCTTAACGCCAAAAGATACTCTTGTGCC
ATTGATGTTTGGTCAGTTGCTTGCATAATGGCAGAAATGATCACTTATAA
ACCGCTTTTTCGAGGTGATTCAGAAATCGATCAATTATTTGCCATTTTCA
AAGTTCTTGGAACTCCTGATAATAAAGTATGGCCAGATTTAGACAAATTT
CCGGGTTGGAATCCATTATTTCCAGTTTGGCGATATGACTTGAGAAGCCG
TTTAGTAGAAGTTATCGATGAAAATTTATTTGATTTGCTAGAGAAAATGT
TAGTTTATCATCCTCTAGAGCGCACAAATATTCGAGACGCTTTATTACAT
GATTATTTTGCCGATTTAGATAAGTCAGATTTGCCAGCTTGTGATTTGGA
AAGGAAATATTCAGATTCGATTAATAAATTTTATCAAGTGTCCAAGTGTG
ACCCCTTGGTGGATAAATCAAATATTCAATAAGAGCAATAGAAAAAATTT
TTATAGAATAAATTTGTACTAATAAATTTCTATTTTATTCTTTTC
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protein sequence of SMED30032688-orf-1

>SMED30032688-orf-1 ID=SMED30032688-orf-1|Name=SMED30032688-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=331bp
MSYQLSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSENDEDGIAP
TTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEEN
PMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADF
GLARCYGAPVKNLTHEVVTLWYRAPEVILNAKRYSCAIDVWSVACIMAEM
ITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPGWNPLFPVWRYD
LRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYFADLDKSDLPA
CDLERKYSDSINKFYQVSKCDPLVDKSNIQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0000166nucleotide binding
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 8..290
e-value: 2.1E-92
score: 322.9
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 8..290
e-value: 3.0E-72
score: 243.2
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 8..290
score: 45.856
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 1..219
e-value: 6.6E-25
score: 85.3
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 89..316
e-value: 5.7E-63
score: 214.4
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 2..88
e-value: 6.9E-30
score: 104.8
NoneNo IPR availablePANTHERPTHR24056CELL DIVISION PROTEIN KINASEcoord: 7..294
NoneNo IPR availablePANTHERPTHR24056:SF379coord: 7..294
NoneNo IPR availableCDDcd07829STKc_CDK_likecoord: 8..290
e-value: 1.6305E-160
score: 447.699
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 14..38
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 126..138
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 4..294