Methylmalonate-semialdehyde dehydrogenase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032682 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Match: ALDH6A1 (aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]) HSP 1 Score: 744.191 bits (1920), Expect = 0.000e+0 Identity = 341/499 (68.34%), Postives = 419/499 (83.97%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI G FV+S++ +WID+ NPATN+VI RVP+ TK EM+ A+ SC AF +W+ SVL+RQQ + + Q+LIK +LK+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L +GETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQH+AVNFICDHP I+AISFVG +KAG +I+ERGS++GKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ AKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV P+M CYKEEIFGPVL+ LE +TLD+AI+++NNNPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 533
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Match: ALDH6A1 (aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]) HSP 1 Score: 723.005 bits (1865), Expect = 0.000e+0 Identity = 336/499 (67.33%), Postives = 410/499 (82.16%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI G FV+S++ +WID+ NPATN+VI RVP+ TK EM+ A+ SC AF +W+ SVL+RQQ K+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L +GETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQH+AVNFICDHP I+AISFVG +KAG +I+ERGS++GKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ AKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV P+M CYKEEIFGPVL+ LE +TLD+AI+++NNNPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQ-------------KEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 520
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Match: ALDH6A1 (aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]) HSP 1 Score: 387.111 bits (993), Expect = 5.125e-132 Identity = 180/252 (71.43%), Postives = 215/252 (85.32%), Query Frame = 3 Query: 864 IGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ AKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV P+M CYKEEIFGPVL+ LE +TLD+AI+++NNNPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 1 MGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 250
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Match: ALDH1A1 (aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402]) HSP 1 Score: 231.106 bits (588), Expect = 2.590e-68 Identity = 160/489 (32.72%), Postives = 249/489 (50.92%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN----VPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN ++ DS + + + NPAT + + +V + K ++++AV++ +AF+ W R + ++KL +LI+RD +A + GK +A + + G ++ + +C + G T+P I + + EP+GV I P+NFP ++ +W +L CGNT+++KP+E+ P + + L EAGFPPG VN++ G A I H I ++F G + G+ I E G N KRV +G K+ +++ DA ++ + F GQ C+A S +FV E+ ++ + RAK + + PG GP I K ++I LIESG KEGAK+ G GY FV PT+ +NV M KEEIFGPV ++ +LDD IK NN YG +FT A + + G V VN V P F +G+ G LG+ F+ +T++KTVT Sbjct: 18 IQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIP-IDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASR-IFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGY----FVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGN-GRELGEYGFHE------YTEVKTVT 493
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Match: ALDH1A3 (aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409]) HSP 1 Score: 230.72 bits (587), Expect = 4.415e-68 Identity = 164/500 (32.80%), Postives = 256/500 (51.20%), Query Frame = 3 Query: 93 ALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES---WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVN-FICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYED-GNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 AL R + + TK+FIN ++ +S++ + NP+T + I V + KP++++AVE+ AF+ W + L+R + + +L +L++RD +AA T + GK L A + G ++ + + + G+T+P D ++V + EP+GV ITP+NFP ++ +W +L CGNTM+LKP+E+ P + L L EAGFPPG VN++ G V I HP+I I+F G + G+ + E S+ N KRV +G KN ++ DA + + F GQ C A S VFV E ++ + AK V + + GP I + ++I LIESG KEGAK+ G S ED G F+ PT+ + V +M KEEIFGPV L+ ++++ IK N+ YG A+FT + A K + G V +N + P F S G+ G+ + +T++KTVT Sbjct: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIP---TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR-VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG-----SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMS-----GNGRELGEYALAEYTEVKTVT 504
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Match: alh-8 (Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52713]) HSP 1 Score: 706.827 bits (1823), Expect = 0.000e+0 Identity = 324/495 (65.45%), Postives = 403/495 (81.41%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAE 1580 S + + A P K++I+G V+S+TT++++L NPATN+VI+ VP T+ EM+ AV+S AF +W S L RQQ MFKLQ LIKRD+KK+A +IT EQGKTL DAEGDV RGLQVVEH CS+ +L +GET+P +++D+D SY+ PLGVTAGI PFNFPAMIPLWMFP++L GNTM++KPSE+DPGA +L+EL EAG P G VN+IHGQH AVNFICD+P I+AISFVGGD AG+HIYERG+KNGKRVQ+N+GAKNHGV+M DA KE T+NQL AAFGAAGQRCMAL+TAV VGE R W+P+++ +AKNLKV+ G +P D+GP+ISK +K R+ LIES KEGA++ LDG N+ V G+E+GNFVGPTIL V P+M CY+EEIFGPVL+ +E + L++AI++INNNPYGNGTAIFT++GATARKFT ++ VGQ+G+NVPIPVPLPMFSFTGSRGSFLGD NFYGK G+ F+TQ KTVTQ W E E Sbjct: 18 FSTSKSAAAAPTVKLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPDGCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEARAWLPELVEKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATARKFTNEVDVGQIGINVPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKTVTQYWNESLTE 512
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Match: alh-8 (Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52713]) HSP 1 Score: 706.827 bits (1823), Expect = 0.000e+0 Identity = 324/495 (65.45%), Postives = 403/495 (81.41%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAE 1580 S + + A P K++I+G V+S+TT++++L NPATN+VI+ VP T+ EM+ AV+S AF +W S L RQQ MFKLQ LIKRD+KK+A +IT EQGKTL DAEGDV RGLQVVEH CS+ +L +GET+P +++D+D SY+ PLGVTAGI PFNFPAMIPLWMFP++L GNTM++KPSE+DPGA +L+EL EAG P G VN+IHGQH AVNFICD+P I+AISFVGGD AG+HIYERG+KNGKRVQ+N+GAKNHGV+M DA KE T+NQL AAFGAAGQRCMAL+TAV VGE R W+P+++ +AKNLKV+ G +P D+GP+ISK +K R+ LIES KEGA++ LDG N+ V G+E+GNFVGPTIL V P+M CY+EEIFGPVL+ +E + L++AI++INNNPYGNGTAIFT++GATARKFT ++ VGQ+G+NVPIPVPLPMFSFTGSRGSFLGD NFYGK G+ F+TQ KTVTQ W E E Sbjct: 18 FSTSKSAAAAPTVKLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPDGCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEARAWLPELVEKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATARKFTNEVDVGQIGINVPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKTVTQYWNESLTE 512
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Match: alh-8 (Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52713]) HSP 1 Score: 706.827 bits (1823), Expect = 0.000e+0 Identity = 324/495 (65.45%), Postives = 403/495 (81.41%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAE 1580 S + + A P K++I+G V+S+TT++++L NPATN+VI+ VP T+ EM+ AV+S AF +W S L RQQ MFKLQ LIKRD+KK+A +IT EQGKTL DAEGDV RGLQVVEH CS+ +L +GET+P +++D+D SY+ PLGVTAGI PFNFPAMIPLWMFP++L GNTM++KPSE+DPGA +L+EL EAG P G VN+IHGQH AVNFICD+P I+AISFVGGD AG+HIYERG+KNGKRVQ+N+GAKNHGV+M DA KE T+NQL AAFGAAGQRCMAL+TAV VGE R W+P+++ +AKNLKV+ G +P D+GP+ISK +K R+ LIES KEGA++ LDG N+ V G+E+GNFVGPTIL V P+M CY+EEIFGPVL+ +E + L++AI++INNNPYGNGTAIFT++GATARKFT ++ VGQ+G+NVPIPVPLPMFSFTGSRGSFLGD NFYGK G+ F+TQ KTVTQ W E E Sbjct: 18 FSTSKSAAAAPTVKLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPDGCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEARAWLPELVEKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATARKFTNEVDVGQIGINVPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKTVTQYWNESLTE 512
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Match: alh-2 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q9TXM0]) HSP 1 Score: 214.927 bits (546), Expect = 1.545e-62 Identity = 148/484 (30.58%), Postives = 246/484 (50.83%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQ-HDAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLK----VSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 T +FIN +FVD+++ + + NPA K++++V + + +++ AVE+ +AF+ W + +R + +L +L++RD +A+ + + GK +A D+ ++ + + G+T+P + D + EP+GV I P+NFP ++ W +L GNT+++K + + P + + + L EA FP G VN+I G+ DA I H + ++F G + G+ I + ++ N K+V +G K+ ++ DA E + Q A F GQ C A S G+ + + +A+AK L + + GP I + E I IESG KEGA++V G V + G FV PTI NVN M+ +EEIFGPV+I + D++++ I+ NN YG + TN A + I G V VN V P F G + S +G G+ G+ +T++KTVT Sbjct: 34 TSLFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDASHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHGKTIP-VGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESNVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYD---EFVAKAKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGG----VKHGDQGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKALQVANTIRAGSVWVNC-YDVFDPAAPFGGFKQSGIGRE--LGEYGLAAYTEVKTVT 506
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Match: alh-1 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q20780]) HSP 1 Score: 196.438 bits (498), Expect = 1.025e-55 Identity = 150/511 (29.35%), Postives = 244/511 (47.75%), Query Frame = 3 Query: 72 RLTLRVHALSRNY------LSTAIPK-TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDA-EGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQ-HDAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADL----GPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 R LR +RN LS P+ T +FIN +FV +++ + + NPA KV+++V + K ++ AV++ AF W + R + +L +L++RD +A+ + + GK A D+ ++ + + + G+T+P I D + EP+GV I P+NFP ++ W +L GNT+++K +E+ P + + + L EAGFP G VN+I G H A I H + ++F G + GR + + ++ N K+V +G K+ ++ DA +++Q F GQ C A S G+ + D +AR+K L + DL GP + E I I +G K+GA++V G + G+FV PTI NV M +EEIFGPV+ + DT+++ ++ NN YG + T A G V VN V F G + S +G G+ G+ +T++KTVT Sbjct: 3 RSALRATVQARNASGVPPGLSNMKPQYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRYYAGWADKNHGKTIP-IEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYD---DFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHG----DQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVMTKDIDKALHIANATRAGSVWVNC-YDVFDAAAPFGGFKQSGIGRE--LGEYGLEAYTEVKTVT 502
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Match: CG17896 (gene:FBgn0023537 transcript:FBtr0070092) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 344/510 (67.45%), Postives = 421/510 (82.55%), Query Frame = 3 Query: 90 HALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 H R+Y S+A P TK+FI+G FV+S+T EWID+ +PATN+V++RVPK T+ EM+ A+ES +AF SWS +S+L RQQ MFKLQ LIK ++ ++A NIT EQGKTL DAEGDV+RGLQVVEHCCSI +LQ+GET+ +A+D+D S PLGVTAG+ PFNFPAMIPLWMFP+++ GNTM+LKPSER PGATM+LMEL EAG PPG VNVIHGQHDAVNFICD P+I+A+SFVG D+AG++IYER KNGKRVQ+N+GAKNHG+++ DA KE+T+NQL GAAFGAAGQRCMALSTAVFVG+ + WIPD++ RA+ LKV+ G PG D+GPVIS +++RI+ LIESG KEGAK++LDGR + V GYEDG FVGPTIL++V PSM+CY EEIFGPVL+ L+ DTLDDAI ++N NPYGNGTA+FT +GA ARKF +I GQVGVNVPIPVPLPMFSFTG+RGSF GD +FYGKQG+ F+TQ KTVTQLWR+ D H +A PTM Sbjct: 13 HLAKRSY-SSAAPTTKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVTQLWRKTDVTHTQ--AAVAMPTM 519
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Match: CG17896 (gene:FBgn0023537 transcript:FBtr0070093) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 344/510 (67.45%), Postives = 421/510 (82.55%), Query Frame = 3 Query: 90 HALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 H R+Y S+A P TK+FI+G FV+S+T EWID+ +PATN+V++RVPK T+ EM+ A+ES +AF SWS +S+L RQQ MFKLQ LIK ++ ++A NIT EQGKTL DAEGDV+RGLQVVEHCCSI +LQ+GET+ +A+D+D S PLGVTAG+ PFNFPAMIPLWMFP+++ GNTM+LKPSER PGATM+LMEL EAG PPG VNVIHGQHDAVNFICD P+I+A+SFVG D+AG++IYER KNGKRVQ+N+GAKNHG+++ DA KE+T+NQL GAAFGAAGQRCMALSTAVFVG+ + WIPD++ RA+ LKV+ G PG D+GPVIS +++RI+ LIESG KEGAK++LDGR + V GYEDG FVGPTIL++V PSM+CY EEIFGPVL+ L+ DTLDDAI ++N NPYGNGTA+FT +GA ARKF +I GQVGVNVPIPVPLPMFSFTG+RGSF GD +FYGKQG+ F+TQ KTVTQLWR+ D H +A PTM Sbjct: 4 HLAKRSY-SSAAPTTKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVTQLWRKTDVTHTQ--AAVAMPTM 510
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Match: CG31075 (gene:FBgn0051075 transcript:FBtr0085080) HSP 1 Score: 218.009 bits (554), Expect = 8.754e-64 Identity = 160/485 (32.99%), Postives = 243/485 (50.10%), Query Frame = 3 Query: 120 AIPK-TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALS-TAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 A PK TK+FIN +FVDS + + NPAT+K I +V + K +++ AV++ +AF W + S L R M KL L+ RD +A+ T + GK +A DV + +++ T+ G+T+P A ++ KEP+GV I P+N+P ++ W + +L G T+I+KP+E+ P + + L EAGFP G +NV++G A I HP I ++F G + GR + + + N KRV +G K+ V+ DA + + A F GQ C A S T V ++ A+AK KV + GP I ++ IESG KEGAK+ G+ + G+ FV PT+ ++V M +EEIFGPV + +L++ I NN YG + TN A KF + G V +N V LP F G + S +G GK G++ + + KT+T Sbjct: 6 AKPKYTKLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIP--AGGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGF----FVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAV-LPSTPFGGYKHSGIGRE--LGKDGLDNYLETKTIT 481
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Match: CG31075 (gene:FBgn0051075 transcript:FBtr0307506) HSP 1 Score: 214.157 bits (544), Expect = 4.050e-62 Identity = 155/479 (32.36%), Postives = 239/479 (49.90%), Query Frame = 3 Query: 135 KMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALS-TAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 ++FIN +FVDS + + NPAT+K I +V + K +++ AV++ +AF W + S L R M KL L+ RD +A+ T + GK +A DV + +++ T+ G+T+P A ++ KEP+GV I P+N+P ++ W + +L G T+I+KP+E+ P + + L EAGFP G +NV++G A I HP I ++F G + GR + + + N KRV +G K+ V+ DA + + A F GQ C A S T V ++ A+AK KV + GP I ++ IESG KEGAK+ G+ + G+ FV PT+ ++V M +EEIFGPV + +L++ I NN YG + TN A KF + G V +N V LP F G + S +G GK G++ + + KT+T Sbjct: 35 QLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTIP--AGGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGF----FVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAV-LPSTPFGGYKHSGIGRE--LGKDGLDNYLETKTIT 504
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Match: Ssadh (gene:FBgn0039349 transcript:FBtr0100569) HSP 1 Score: 207.994 bits (528), Expect = 8.022e-60 Identity = 134/493 (27.18%), Postives = 248/493 (50.30%), Query Frame = 3 Query: 93 ALSRNYLSTAIPKTKMFINGDFVDSQTTEW-IDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES--WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV--NFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 +L R +A+ + K ++G +VDS + ++ NPA VI +VP T + ++A+++ +A+ES W + +R + K +LI++ ++IA +T+E GK + +++G+V G VE GE +P + + +I+ K+P+GV A ITP+NFP + +L G T+++KPSE P + + +L V+AG P G +NV+ A + C P +R ISF G + G+ ++ + KR+ +G ++ A E ++ + + F GQ C++ + FV ++ ++ + R + LK+ +G +GP+I++ ++ +E + A I+L G+ L G F PTI+T+V PS + Y EE+FGPV+ + ++A+K N+ G ++ + + +++ VG VGVN I + F G + S +G K G++ + +K + Sbjct: 16 SLCRMRGFSALVQDKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVS-ANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKG---SLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGI-ISAAEAPFGGVKESGVGREG--SKHGIDDYVDIKYI 501
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Match: aldh6a1 (aldehyde dehydrogenase 6 family, member A1 [Source:ZFIN;Acc:ZDB-GENE-030131-9192]) HSP 1 Score: 758.444 bits (1957), Expect = 0.000e+0 Identity = 346/520 (66.54%), Postives = 434/520 (83.46%), Query Frame = 3 Query: 60 IASKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 I +R+ L+V R S+++P TK+FI+G FV+S++++W+D+ NPAT++VI RVPK T+ EM AV+SC+ AF++WS+ S+L RQQ F+ Q+LIK ++K++A IT EQGKTL DAEGDV RGLQVVEH CSIT+L LGET+P + KD+D +Y+ P+GV AGI PFNFPAMIPLWMFP+ +VCGNT +LKPSER PG TMML +L +AG P GT+N+IHGQHDAVNFICDHP IRAISFVG ++AG +IYERGSKNGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTA+ VGE R+W+P+++ RAK+L+V+ G QPGAD+GP+IS AKER++SLI+SG EGAK++LDGRN+KV GYE+GNFVGPTI++NV P M CYKEEIFGPVL+ LE D+LD+AIK++N NPYGNGTAIFT +GA ARK++ ++ VGQ+GVNVPIPVPLPMFSFTGSRGSF GDTNFYGKQG+ F+TQ+KT+T W+ EDA K A PTM Sbjct: 9 IVKRRVPLQV---GRMCYSSSVPTTKLFIDGKFVESKSSQWLDIHNPATSEVIGRVPKATQEEMLAAVDSCSRAFQTWSETSILARQQIFFRYQQLIKDNIKELAKLITLEQGKTLADAEGDVFRGLQVVEHTCSITSLMLGETLPSLTKDMDTYTYRLPIGVCAGIAPFNFPAMIPLWMFPMGMVCGNTYLLKPSERVPGCTMMLAKLLQDAGAPDGTLNIIHGQHDAVNFICDHPAIRAISFVGSNQAGEYIYERGSKNGKRVQSNMGAKNHGVIMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEARDWLPELVERAKSLRVNAGDQPGADVGPLISPQAKERVNSLIQSGVDEGAKVLLDGRNVKVKGYENGNFVGPTIISNVTPEMTCYKEEIFGPVLVVLEADSLDEAIKIVNKNPYGNGTAIFTTNGAAARKYSHEVDVGQIGVNVPIPVPLPMFSFTGSRGSFRGDTNFYGKQGIQFYTQIKTITSQWKAEDATL--KSPAVTMPTM 523
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Match: aldh9a1a.1 (aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 [Source:NCBI gene;Acc:100005587]) HSP 1 Score: 226.098 bits (575), Expect = 1.670e-66 Identity = 140/462 (30.30%), Postives = 228/462 (49.35%), Query Frame = 3 Query: 195 NPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSG--YEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV----PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 PAT +V+ + C + E+++A++S A+ WSQ S + R + M + +I+ IA + GK++ +AE D+ Q +E+ I G+ +PG + + +EPLGV GI +N+P I W +L CGN M+ KPS P +ML E+ EAG P G NV+ G + + +C HP + +SF G G+ + E +K+ K+V +G K+ ++ D E+ I + A F G+ C T VFV ++ +++ R K + V + + G +G +ISK E++ I+ ++G K++ G + +DG FV P +L N M C KEEIFGPV+ L DT ++ ++ NN +G + +FT A A + + G +N P+ VP F G + S G N G + +++QLKTV Sbjct: 47 EPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAY---TRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCN-GTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVP-----FGGYKMSGFGREN--GTVTIEYYSQLKTV 497
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Match: aldh9a1a.1 (aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 [Source:NCBI gene;Acc:100005587]) HSP 1 Score: 226.098 bits (575), Expect = 1.670e-66 Identity = 140/462 (30.30%), Postives = 228/462 (49.35%), Query Frame = 3 Query: 195 NPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSG--YEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV----PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 PAT +V+ + C + E+++A++S A+ WSQ S + R + M + +I+ IA + GK++ +AE D+ Q +E+ I G+ +PG + + +EPLGV GI +N+P I W +L CGN M+ KPS P +ML E+ EAG P G NV+ G + + +C HP + +SF G G+ + E +K+ K+V +G K+ ++ D E+ I + A F G+ C T VFV ++ +++ R K + V + + G +G +ISK E++ I+ ++G K++ G + +DG FV P +L N M C KEEIFGPV+ L DT ++ ++ NN +G + +FT A A + + G +N P+ VP F G + S G N G + +++QLKTV Sbjct: 47 EPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAY---TRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCN-GTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVP-----FGGYKMSGFGREN--GTVTIEYYSQLKTV 497
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Match: aldh9a1a.1 (aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 [Source:NCBI gene;Acc:100005587]) HSP 1 Score: 226.098 bits (575), Expect = 1.670e-66 Identity = 140/462 (30.30%), Postives = 228/462 (49.35%), Query Frame = 3 Query: 195 NPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSG--YEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV----PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 PAT +V+ + C + E+++A++S A+ WSQ S + R + M + +I+ IA + GK++ +AE D+ Q +E+ I G+ +PG + + +EPLGV GI +N+P I W +L CGN M+ KPS P +ML E+ EAG P G NV+ G + + +C HP + +SF G G+ + E +K+ K+V +G K+ ++ D E+ I + A F G+ C T VFV ++ +++ R K + V + + G +G +ISK E++ I+ ++G K++ G + +DG FV P +L N M C KEEIFGPV+ L DT ++ ++ NN +G + +FT A A + + G +N P+ VP F G + S G N G + +++QLKTV Sbjct: 47 EPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAY---TRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCN-GTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVP-----FGGYKMSGFGREN--GTVTIEYYSQLKTV 497
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Match: aldh9a1a.1 (aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 [Source:NCBI gene;Acc:100005587]) HSP 1 Score: 226.098 bits (575), Expect = 1.670e-66 Identity = 140/462 (30.30%), Postives = 228/462 (49.35%), Query Frame = 3 Query: 195 NPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSG--YEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV----PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 PAT +V+ + C + E+++A++S A+ WSQ S + R + M + +I+ IA + GK++ +AE D+ Q +E+ I G+ +PG + + +EPLGV GI +N+P I W +L CGN M+ KPS P +ML E+ EAG P G NV+ G + + +C HP + +SF G G+ + E +K+ K+V +G K+ ++ D E+ I + A F G+ C T VFV ++ +++ R K + V + + G +G +ISK E++ I+ ++G K++ G + +DG FV P +L N M C KEEIFGPV+ L DT ++ ++ NN +G + +FT A A + + G +N P+ VP F G + S G N G + +++QLKTV Sbjct: 47 EPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAY---TRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCN-GTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVP-----FGGYKMSGFGREN--GTVTIEYYSQLKTV 497
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Match: tlr3 (toll like receptor 3 [Source:Xenbase;Acc:XB-GENE-491049]) HSP 1 Score: 748.429 bits (1931), Expect = 0.000e+0 Identity = 343/502 (68.33%), Postives = 420/502 (83.67%), Query Frame = 3 Query: 114 STAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 S A+P+TK+FING FVDS+T+EWID+ NPATN+VI RVP+ T+ EME AV +C F +WS+ S+LNRQQ + Q+LIK +LK++A IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGET+ + KD+D +++ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM L++L +AG P GT+N+IHGQH AVNFICDHP IRAISFVG ++AG +IY+RGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ +AK L+V+ G QPGADLGP+IS AK+R+ SL+ESG +EGA ++LDGR++ V G+E+GNFVGPTIL NV P M CYKEEIFGPVL+ LE DTLDDA+K++N+NPYGNGTAIFT +GATARK+T + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQGV+F+TQLKTVT W+EED+ S A PTM Sbjct: 22 SAAVPRTKLFINGQFVDSETSEWIDVHNPATNEVIGRVPQATQSEMEAAVNACQRTFPAWSETSILNRQQIFLRYQQLIKDNLKEVARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETLSSLTKDMDTFTFRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTYLMKPSERVPGATMFLVQLLQDAGVPDGTINIIHGQHAAVNFICDHPAIRAISFVGSNQAGEYIYDRGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKQWLPELVEKAKKLQVNAGDQPGADLGPLISPAAKDRVCSLVESGVREGATLLLDGRDVNVKGFENGNFVGPTILANVQPHMTCYKEEIFGPVLVILEADTLDDALKIVNSNPYGNGTAIFTTNGATARKYTHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGVHFYTQLKTVTSQWKEEDSTLTSP--AVVMPTM 521
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Match: tlr3 (toll like receptor 3 [Source:Xenbase;Acc:XB-GENE-491049]) HSP 1 Score: 745.347 bits (1923), Expect = 0.000e+0 Identity = 341/503 (67.79%), Postives = 419/503 (83.30%), Query Frame = 3 Query: 111 LSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 + + P+TK+FING FVDS+T+EWID+ NPATN+VI RVP+ T+ EME AV +C F +WS+ S+LNRQQ + Q+LIK +LK++A IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGET+ + KD+D +++ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM L++L +AG P GT+N+IHGQH AVNFICDHP IRAISFVG ++AG +IY+RGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ +AK L+V+ G QPGADLGP+IS AK+R+ SL+ESG +EGA ++LDGR++ V G+E+GNFVGPTIL NV P M CYKEEIFGPVL+ LE DTLDDA+K++N+NPYGNGTAIFT +GATARK+T + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQGV+F+TQLKTVT W+EED+ S A PTM Sbjct: 46 IKSVFPRTKLFINGQFVDSETSEWIDVHNPATNEVIGRVPQATQSEMEAAVNACQRTFPAWSETSILNRQQIFLRYQQLIKDNLKEVARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETLSSLTKDMDTFTFRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTYLMKPSERVPGATMFLVQLLQDAGVPDGTINIIHGQHAAVNFICDHPAIRAISFVGSNQAGEYIYDRGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKQWLPELVEKAKKLQVNAGDQPGADLGPLISPAAKDRVCSLVESGVREGATLLLDGRDVNVKGFENGNFVGPTILANVQPHMTCYKEEIFGPVLVILEADTLDDALKIVNSNPYGNGTAIFTTNGATARKYTHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGVHFYTQLKTVTSQWKEEDSTLTSP--AVVMPTM 546
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Match: tlr3 (toll like receptor 3 [Source:Xenbase;Acc:XB-GENE-491049]) HSP 1 Score: 743.036 bits (1917), Expect = 0.000e+0 Identity = 341/498 (68.47%), Postives = 417/498 (83.73%), Query Frame = 3 Query: 126 PKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 P+TK+FING FVDS+T+EWID+ NPATN+VI RVP+ T+ EME AV +C F +WS+ S+LNRQQ + Q+LIK +LK++A IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGET+ + KD+D +++ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM L++L +AG P GT+N+IHGQH AVNFICDHP IRAISFVG ++AG +IY+RGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ +AK L+V+ G QPGADLGP+IS AK+R+ SL+ESG +EGA ++LDGR++ V G+E+GNFVGPTIL NV P M CYKEEIFGPVL+ LE DTLDDA+K++N+NPYGNGTAIFT +GATARK+T + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQGV+F+TQLKTVT W+EED+ S A PTM Sbjct: 20 PRTKLFINGQFVDSETSEWIDVHNPATNEVIGRVPQATQSEMEAAVNACQRTFPAWSETSILNRQQIFLRYQQLIKDNLKEVARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETLSSLTKDMDTFTFRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTYLMKPSERVPGATMFLVQLLQDAGVPDGTINIIHGQHAAVNFICDHPAIRAISFVGSNQAGEYIYDRGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKQWLPELVEKAKKLQVNAGDQPGADLGPLISPAAKDRVCSLVESGVREGATLLLDGRDVNVKGFENGNFVGPTILANVQPHMTCYKEEIFGPVLVILEADTLDDALKIVNSNPYGNGTAIFTTNGATARKYTHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGVHFYTQLKTVTSQWKEEDSTLTSP--AVVMPTM 515
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Match: tlr3 (toll like receptor 3 [Source:Xenbase;Acc:XB-GENE-491049]) HSP 1 Score: 742.651 bits (1916), Expect = 0.000e+0 Identity = 341/498 (68.47%), Postives = 417/498 (83.73%), Query Frame = 3 Query: 126 PKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 P+TK+FING FVDS+T+EWID+ NPATN+VI RVP+ T+ EME AV +C F +WS+ S+LNRQQ + Q+LIK +LK++A IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGET+ + KD+D +++ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM L++L +AG P GT+N+IHGQH AVNFICDHP IRAISFVG ++AG +IY+RGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ +AK L+V+ G QPGADLGP+IS AK+R+ SL+ESG +EGA ++LDGR++ V G+E+GNFVGPTIL NV P M CYKEEIFGPVL+ LE DTLDDA+K++N+NPYGNGTAIFT +GATARK+T + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQGV+F+TQLKTVT W+EED+ S A PTM Sbjct: 27 PRTKLFINGQFVDSETSEWIDVHNPATNEVIGRVPQATQSEMEAAVNACQRTFPAWSETSILNRQQIFLRYQQLIKDNLKEVARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETLSSLTKDMDTFTFRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTYLMKPSERVPGATMFLVQLLQDAGVPDGTINIIHGQHAAVNFICDHPAIRAISFVGSNQAGEYIYDRGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKQWLPELVEKAKKLQVNAGDQPGADLGPLISPAAKDRVCSLVESGVREGATLLLDGRDVNVKGFENGNFVGPTILANVQPHMTCYKEEIFGPVLVILEADTLDDALKIVNSNPYGNGTAIFTTNGATARKYTHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGVHFYTQLKTVTSQWKEEDSTLTSP--AVVMPTM 522
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Match: tlr3 (toll like receptor 3 [Source:Xenbase;Acc:XB-GENE-491049]) HSP 1 Score: 742.265 bits (1915), Expect = 0.000e+0 Identity = 341/498 (68.47%), Postives = 417/498 (83.73%), Query Frame = 3 Query: 126 PKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 P+TK+FING FVDS+T+EWID+ NPATN+VI RVP+ T+ EME AV +C F +WS+ S+LNRQQ + Q+LIK +LK++A IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGET+ + KD+D +++ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM L++L +AG P GT+N+IHGQH AVNFICDHP IRAISFVG ++AG +IY+RGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ +AK L+V+ G QPGADLGP+IS AK+R+ SL+ESG +EGA ++LDGR++ V G+E+GNFVGPTIL NV P M CYKEEIFGPVL+ LE DTLDDA+K++N+NPYGNGTAIFT +GATARK+T + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQGV+F+TQLKTVT W+EED+ S A PTM Sbjct: 31 PRTKLFINGQFVDSETSEWIDVHNPATNEVIGRVPQATQSEMEAAVNACQRTFPAWSETSILNRQQIFLRYQQLIKDNLKEVARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETLSSLTKDMDTFTFRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTYLMKPSERVPGATMFLVQLLQDAGVPDGTINIIHGQHAAVNFICDHPAIRAISFVGSNQAGEYIYDRGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKQWLPELVEKAKKLQVNAGDQPGADLGPLISPAAKDRVCSLVESGVREGATLLLDGRDVNVKGFENGNFVGPTILANVQPHMTCYKEEIFGPVLVILEADTLDDALKIVNSNPYGNGTAIFTTNGATARKYTHLVDVGQVGVNVPIPVPLPMFSFTGSRASFRGDTNFYGKQGVHFYTQLKTVTSQWKEEDSTLTS--PAVVMPTM 526
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Match: Aldh6a1 (aldehyde dehydrogenase family 6, subfamily A1 [Source:MGI Symbol;Acc:MGI:1915077]) HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0 Identity = 344/499 (68.94%), Postives = 422/499 (84.57%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI+G FV+S++ +WID+ NPATN+V+ RVP+ TK EM+ AVESC AF +W+ S+L+RQQ + + Q+LIK +LK+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQHDAVNFICDHP I+AISFVG ++AG +I+ERGS+NGKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTA+ VGE + W+P+++ RAKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV PSM CYKEEIFGPVL+ LE +TLD+AIK++N+NPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMDAAVESCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHDAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVDRAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRRIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGATARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 533
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Match: Aldh1a7 (aldehyde dehydrogenase family 1, subfamily A7 [Source:MGI Symbol;Acc:MGI:1347050]) HSP 1 Score: 231.491 bits (589), Expect = 1.355e-68 Identity = 162/489 (33.13%), Postives = 247/489 (50.51%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN--VPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN ++ DS +++ + NPAT +VI V + K ++++AV++ +AF+ W R + + KL +L++RD +A + GK A DV ++ +++ + G+T+P D +I +Y +EP+GV I P+N P +I W +L CGNT+++KP+E+ P + + L EAGFPPG VN++ G A I H I +SF G + G+ I E G N KRV +G K+ ++ DA +S + F GQ C+A S +FV E+ ++ + RAK + + G + GP I K +I LIESG KEGAK+ G G+ FV PT+ +NV M KEEIFGPV ++ ++DD IK NN YG +FT A + + G V VN + +PV P F S G+ G+ G+ +T+LKTV Sbjct: 18 IQHTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMESMNAGKVFAHAYLLDVEISIKALQYFAGWADKIHGQTIP---SDGNIFTYTRREPIGVCGQIIPWNGPLIIFTWKLGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGGAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASR-LFVEESIYDEFVRRSVERAKKYILGNPLNSGINQGPQIDKEQHNKILGLIESGKKEGAKLECGGGRWGNKGF----FVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSMDDVIKRANNTTYGLAAGVFTKDLDKAITVSSALQAGMVWVNCYLAVPVQCPFGGFKMS-----GNGRELGEHGLYEYTELKTVA 493
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Match: Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1 [Source:MGI Symbol;Acc:MGI:1353450]) HSP 1 Score: 231.491 bits (589), Expect = 1.473e-68 Identity = 160/489 (32.72%), Postives = 248/489 (50.72%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAE-GDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSF--LGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN ++ +S + + + NPAT +VI V + K ++++AV++ +AF+ W R + + KL +L++RD +A GK +A D+ ++ +++C + G+T+P D DI +Y +EP+GV I P+NFP ++ +W +L CGNT+++KP+E+ P + L L EAGFPPG VN++ G A I H + ++F G + G+ I E G N KRV +G K+ ++ DA + + F GQ C+A S +FV E+ ++ + RAK + + PG + GP I K ++I LIESG KEGAK+ G G+ FV PT+ +NV M KEEIFGPV ++ ++DD IK NN YG +FT A + + G V VN + M S G F G+ G+ G+ +T+LKTV Sbjct: 18 IQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIP---SDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASR-IFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGF----FVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYM-----MLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVA 493
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Match: Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1 [Source:MGI Symbol;Acc:MGI:1353450]) HSP 1 Score: 231.491 bits (589), Expect = 1.473e-68 Identity = 160/489 (32.72%), Postives = 248/489 (50.72%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAE-GDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSF--LGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN ++ +S + + + NPAT +VI V + K ++++AV++ +AF+ W R + + KL +L++RD +A GK +A D+ ++ +++C + G+T+P D DI +Y +EP+GV I P+NFP ++ +W +L CGNT+++KP+E+ P + L L EAGFPPG VN++ G A I H + ++F G + G+ I E G N KRV +G K+ ++ DA + + F GQ C+A S +FV E+ ++ + RAK + + PG + GP I K ++I LIESG KEGAK+ G G+ FV PT+ +NV M KEEIFGPV ++ ++DD IK NN YG +FT A + + G V VN + M S G F G+ G+ G+ +T+LKTV Sbjct: 18 IQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIP---SDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASR-IFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGF----FVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYM-----MLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVA 493
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Match: Aldh1a3 (aldehyde dehydrogenase family 1, subfamily A3 [Source:MGI Symbol;Acc:MGI:1861722]) HSP 1 Score: 226.098 bits (575), Expect = 2.084e-66 Identity = 164/500 (32.80%), Postives = 249/500 (49.80%), Query Frame = 3 Query: 93 ALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES---WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVN-FICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYED-GNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFL--GDTNFYGKQGVNFFTQLKTVT 1553 AL R + + TK+FIN D+ +S++ NP+T + I V + KP++++AVE+ AF+ W + L+R Q + +L +L++RD +A T + GK L A + G ++ + + G T+P D ++V + EP+GV ITP+NFP ++ W +L CGNT++LKP+E+ P + L L E GFPPG VN++ G V I HP+I I+F G + G+ + E S+ N KRV +G KN ++ DA + + F GQ C A S VFV E ++ + AK V + + GP I + ++I LIESG KEGAK+ G S ED G F+ PT+ ++V +M KEEIFGPV L+ L++ IK N+ YG A+FT + A K + G V +N F G F G+ G+ + +T++KTVT Sbjct: 19 ALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIP---TDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR-VFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG-----SAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINC-----YNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Match: sp|Q17M80|MMSA_AEDAE (Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Aedes aegypti OX=7159 GN=AAEL001134 PE=3 SV=1) HSP 1 Score: 772.311 bits (1993), Expect = 0.000e+0 Identity = 364/510 (71.37%), Postives = 437/510 (85.69%), Query Frame = 3 Query: 90 HALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +AL R+Y + ++P TKMFI+G FVDS+TTEWIDL +PATNKV++RVPKCT+ EME AVES +AF++WSQ S+L RQQ MFKLQ LI+ ++ ++A NIT EQGKTL+DAEGDV+RGLQVVEHCCSIT+LQ+GET+P IAKD+D SY PLGVTAGI PFNFPAMIPLWMFP+++ CGNT I+KPSER PGATMMLMEL EAG PPG VNVIHG HDAVNFICD+P I+A+SFVG D+AG++IYER +NGKRVQ+N+GAKNHGV+M DA KE+T+NQL GAAFGAAGQRCMALSTAVFVGE + WIPD++ RA+ LKV+ G PG D+GPVIS +K+RI+ L+ESG KEGAK+VLDGR++KV +E+GNFVGPTILT+V+ +M+CY EEIFGPVL+CL VDT+D+A+++INNNPYGNGTAIFT +GATARKF +I VGQVGVNVPIPVPLPMFSFTGSRGSF+GD +FYGKQGV F+TQ KTVTQLWRE D H +A PTM Sbjct: 13 NALQRSYSTASVPTTKMFIDGKFVDSKTTEWIDLHDPATNKVVTRVPKCTQDEMESAVESSKKAFKTWSQTSILGRQQVMFKLQHLIRNNMSELAKNITKEQGKTLVDAEGDVLRGLQVVEHCCSITSLQMGETVPNIAKDMDTYSYTLPLGVTAGICPFNFPAMIPLWMFPVAITCGNTSIIKPSERVPGATMMLMELLNEAGCPPGVVNVIHGAHDAVNFICDNPTIKAVSFVGSDQAGKYIYERAGRNGKRVQSNMGAKNHGVIMADANKENTLNQLAGAAFGAAGQRCMALSTAVFVGEAKQWIPDLVERARKLKVNAGHVPGTDVGPVISPQSKQRINELVESGVKEGAKLVLDGRSIKVENFENGNFVGPTILTDVSTNMKCYTEEIFGPVLVCLTVDTVDEAVEMINNNPYGNGTAIFTTNGATARKFVNEIDVGQVGVNVPIPVPLPMFSFTGSRGSFMGDCHFYGKQGVKFYTQTKTVTQLWREGDVSHTK--AAVAMPTM 520
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Match: sp|Q7QC84|MMSA_ANOGA (Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Anopheles gambiae OX=7165 GN=AGAP002499 PE=3 SV=2) HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0 Identity = 359/510 (70.39%), Postives = 432/510 (84.71%), Query Frame = 3 Query: 90 HALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 + L R Y + ++P TKMFI+G FV+S+T +WIDL +PATN+V++RVPKCT+ EM+ AVES +A+++W Q S+L+RQQ M KLQ +I+ ++ ++A NIT EQGKTL+DAEGDV+RGLQVVEHCCSIT+LQ+GET+P IAKD+D SY PLGVTAGI PFNFPAMIPLWMFP+++ CGNT I+KPSER PGATM+LME+ EAG PPG VNVIHG HDAVNF+CD+P IRA+SFVG D+AG++IYER +NGKRVQ N+GAKNHGV+M DA KE+T+NQL GAAFGAAGQRCMALSTAVFVGE RNWIPD++ RA+ LKV+ G PG DLGPVIS +K+RI+ L+ESG KEGAKIVLDGRN+KV G+E GNFVGPTI+++V P+M+CY EEIFGPVL+CL VDT+D+AI+LINNNPYGNGTAIFT +GATARKF I VGQVGVNVPIPVPLPMFSFTGSRGSFLGD +FYGKQG+ F+TQ KTVTQLWRE D H +A PTM Sbjct: 13 NVLQRGYSTASVPTTKMFIDGKFVESKTNDWIDLHDPATNEVVTRVPKCTQDEMQTAVESSKKAYKTWRQSSILSRQQVMLKLQHIIRNNMSELAKNITKEQGKTLIDAEGDVLRGLQVVEHCCSITSLQMGETVPNIAKDMDTYSYHLPLGVTAGIAPFNFPAMIPLWMFPVAITCGNTSIIKPSERVPGATMLLMEMLNEAGCPPGVVNVIHGAHDAVNFVCDNPDIRAVSFVGSDQAGKYIYERAGRNGKRVQCNMGAKNHGVIMADANKENTLNQLAGAAFGAAGQRCMALSTAVFVGEARNWIPDLVERARKLKVNAGHLPGTDLGPVISPQSKQRINELVESGAKEGAKIVLDGRNIKVEGFEKGNFVGPTIISDVTPNMKCYTEEIFGPVLVCLSVDTIDEAIELINNNPYGNGTAIFTTNGATARKFVNDIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDCHFYGKQGIKFYTQTKTVTQLWREGDVSHTK--AAVAMPTM 520
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Match: sp|Q9EQ20|MMSA_MOUSE (Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Mus musculus OX=10090 GN=Aldh6a1 PE=1 SV=1) HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0 Identity = 344/499 (68.94%), Postives = 422/499 (84.57%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI+G FV+S++ +WID+ NPATN+V+ RVP+ TK EM+ AVESC AF +W+ S+L+RQQ + + Q+LIK +LK+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQHDAVNFICDHP I+AISFVG ++AG +I+ERGS+NGKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTA+ VGE + W+P+++ RAKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV PSM CYKEEIFGPVL+ LE +TLD+AIK++N+NPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMDAAVESCKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHDAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAILVGEAKKWLPELVDRAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRRIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGATARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 533
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Match: sp|Q02253|MMSA_RAT (Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Rattus norvegicus OX=10116 GN=Aldh6a1 PE=1 SV=1) HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0 Identity = 341/499 (68.34%), Postives = 419/499 (83.97%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI+G FV+S++ +WID+ NPATN+V+ RVP+ TK EME AV +C AF +W+ S+L+RQQ + + Q+LIK +LK+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L LGETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQH+AVNFICDHP I+AISFVG ++AG +I+ERGS+NGKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ RAKNL+V+ G QPGADLGP+I+ AKER+ +LI+SG KEGA I+LDGR +KV GYE+GNFVGPTI++NV PSM CYKEEIFGPVL+ LE +TLD+AIK++N+NPYGNGTAIFT +GA ARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMEAAVAACKRAFPAWADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVERAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGAKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPSMTCYKEEIFGPVLVVLETETLDEAIKIVNDNPYGNGTAIFTTNGAIARKYAHMVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 533
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Match: sp|Q02252|MMSA_HUMAN (Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2) HSP 1 Score: 744.191 bits (1920), Expect = 0.000e+0 Identity = 341/499 (68.34%), Postives = 419/499 (83.97%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 +P K+FI G FV+S++ +WID+ NPATN+VI RVP+ TK EM+ A+ SC AF +W+ SVL+RQQ + + Q+LIK +LK+IA IT EQGKTL DAEGDV RGLQVVEH CS+T+L +GETMP I KD+D+ SY+ PLGV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER PGATM+L +L ++G P GT+N+IHGQH+AVNFICDHP I+AISFVG +KAG +I+ERGS++GKRVQAN+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE + W+P+++ AKNL+V+ G QPGADLGP+I+ AKER+ +LI+SGTKEGA I+LDGR +KV GYE+GNFVGPTI++NV P+M CYKEEIFGPVL+ LE +TLD+AI+++NNNPYGNGTAIFT +GATARK+ + VGQVGVNVPIPVPLPMFSFTGSR SF GDTNFYGKQG+ F+TQLKT+T W+EEDA S A PTM Sbjct: 37 VPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSS--PAVVMPTM 533
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Match: V5IF88 (Putative methylmalonate semialdehyde dehydrogenase (Fragment) OS=Ixodes ricinus OX=34613 PE=2 SV=1) HSP 1 Score: 803.512 bits (2074), Expect = 0.000e+0 Identity = 374/508 (73.62%), Postives = 431/508 (84.84%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 L+R Y + A+P TKMFING FV+S+TTEW+DL NPATN++I+RVPKCT EM AV S EAF +WSQ S+L RQQ MFKLQ+LIK ++K++AAN+T EQGKTL DAEGDV+RGLQVVEH C +T+LQLGET+P I KD+D +SY+ PLGVTAGITPFNFPAMIPLWMFPL+LVCGNTM+LKPSERDPG TMMLMEL + G P G VNVIHG HDAV FICDHP IRAISFVG D+AG+ IYERGSKNGKRVQ N+GAKNHGV+MPDA KE T+NQL GAAFGAAGQRCMALSTAVFVGE +NWIP+++ RA+ LKV+ G PGADLGPVIS AKERI L+ESG +EGAK++LDGR + V GYE GNFVGPT+L +V P M CY+EEIFGPVL+ L VD++DDAI LIN+NPYGNGTAIFT +GATARK+TQ+I VGQVGVNVPIPVPLPMFSFTGSRGSFLGD NFYGK GVNF+TQLKTVTQLWR +D+ H +AT P M Sbjct: 14 LTRGY-AAAVPNTKMFINGQFVESKTTEWVDLKNPATNELITRVPKCTNAEMHEAVRSAKEAFRTWSQTSILTRQQSMFKLQQLIKENMKRLAANVTEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSITKDMDTMSYRIPLGVTAGITPFNFPAMIPLWMFPLALVCGNTMVLKPSERDPGCTMMLMELLKQTGVPDGVVNVIHGTHDAVKFICDHPDIRAISFVGSDQAGKFIYERGSKNGKRVQCNMGAKNHGVVMPDANKEYTLNQLTGAAFGAAGQRCMALSTAVFVGEAKNWIPELVERARKLKVNAGHVPGADLGPVISPEAKERICDLVESGVQEGAKLLLDGRGIVVPGYEKGNFVGPTVLADVTPQMRCYQEEIFGPVLLTLSVDSMDDAIALINSNPYGNGTAIFTTNGATARKYTQEIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDANFYGKAGVNFYTQLKTVTQLWRTQDSTHSK--AATAMPVM 518
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Match: A0A4D5RHE7 (Putative methylmalonate-semialdehyde dehydrogenase acylating mitochondrial (Fragment) OS=Ixodes scapularis OX=6945 PE=4 SV=1) HSP 1 Score: 802.357 bits (2071), Expect = 0.000e+0 Identity = 373/508 (73.43%), Postives = 431/508 (84.84%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 L+R Y + A+P TKMFING FV+S+TTEW+DL NPATN++I+RVPKCT EM AV S EAF +WSQ S+L RQQ MFKLQ+LIK ++K++AAN+T EQGKTL DAEGDV+RGLQVVEH C +T+LQLGET+P I KD+D +SY+ PLGVTAGITPFNFPAMIPLWMFPL+LVCGNTM+LKPSERDPG TMMLMEL + G P G VNVIHG HDAV FICDHP IRAISFVG D+AG+ IYERGSKNGKRVQ N+GAKNHGV+MPDA KE T+NQL GAAFGAAGQRCMALSTAVFVGE +NWIP+++ RA+ LKV+ G +PGADLGPVIS AKERI L+ESG KEGAK++LDGR + + GYE GNFVGPT+L +V P M CY+EEIFGPVL+ L VD++DDAI LIN+NPYGNGTAIFT +GATARK+TQ+I V QVGVNVPIPVPLPMFSFTGSRGSFLGD NFYGK GVNF+TQLKTVTQLWR +D+ H +AT P M Sbjct: 18 LTRGY-AAAVPNTKMFINGQFVESKTTEWVDLKNPATNELITRVPKCTNAEMHEAVRSAKEAFRTWSQTSILTRQQSMFKLQQLIKENMKRLAANVTEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSITKDMDTMSYRIPLGVTAGITPFNFPAMIPLWMFPLALVCGNTMVLKPSERDPGCTMMLMELLKQTGVPDGVVNVIHGTHDAVKFICDHPDIRAISFVGSDQAGKFIYERGSKNGKRVQCNMGAKNHGVVMPDANKEYTLNQLTGAAFGAAGQRCMALSTAVFVGEAKNWIPELVERARKLKVNAGHEPGADLGPVISPEAKERICDLVESGVKEGAKLLLDGRGIVMPGYEKGNFVGPTVLADVTPQMRCYQEEIFGPVLLTLSVDSMDDAIALINSNPYGNGTAIFTTNGATARKYTQEIDVRQVGVNVPIPVPLPMFSFTGSRGSFLGDANFYGKAGVNFYTQLKTVTQLWRTQDSTHSK--AATAMPVM 522
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Match: A0A131YMU9 (Methylmalonate-semialdehyde dehydrogenase OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1) HSP 1 Score: 800.431 bits (2066), Expect = 0.000e+0 Identity = 377/516 (73.06%), Postives = 433/516 (83.91%), Query Frame = 3 Query: 72 RLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 R TL R Y S+++P TKMFING FV+S+TTEWIDL NPATN+ ++RVP CT EME AV + EAF++WSQ S+L RQQ MFKLQ LIK ++K+IAANIT EQGKTL DAEGDV+RGLQVVEH C +T+LQLGET+P I+KD+D +SY+ PLGV AGITPFNFPAMIPLWMFPL+LVCGNTM++KPSERDPGATM+LMEL E G P G VNV HG H++V FICDHP IRAISFVG D AG+ IYERGSKNGKRVQ N+GAKNHGV+MPDA KE T+NQL GAAFGAAGQRCMALSTAVFVGE +NWIP+++ RAK L V+ G PGADLGPVIS AK+RI L+ESG KEGAKI+LDGRN+KV G+E GNFVGPTILT+V PSM CY+EEIFGPVL+ L VDT+D+AI LIN+NPYGNGTAIFT +GATAR++TQ+I VGQVGVNVPIPVPLPMFSFTGSRGSFLGD NFYGK GVNF+TQLKTVTQLWR +D+ H AT P M Sbjct: 11 RTTLLRRFPIRGYASSSVPTTKMFINGQFVESKTTEWIDLMNPATNEPVTRVPICTNDEMEAAVSAAKEAFKTWSQTSILTRQQSMFKLQNLIKENMKRIAANITEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSISKDMDTLSYRIPLGVCAGITPFNFPAMIPLWMFPLALVCGNTMVIKPSERDPGATMILMELLQECGVPNGVVNVFHGTHESVRFICDHPDIRAISFVGSDTAGKFIYERGSKNGKRVQCNMGAKNHGVIMPDANKEYTLNQLTGAAFGAAGQRCMALSTAVFVGEAKNWIPELVERAKKLNVNAGHVPGADLGPVISPEAKQRICDLVESGAKEGAKIILDGRNIKVPGFEKGNFVGPTILTDVKPSMRCYREEIFGPVLLTLNVDTMDEAISLINSNPYGNGTAIFTTNGATARRYTQEIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDNNFYGKAGVNFYTQLKTVTQLWRAQDSTHAK--PATAMPVM 524
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Match: A0A224YTE8 (Methylmalonate-semialdehyde dehydrogenase OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1) HSP 1 Score: 799.66 bits (2064), Expect = 0.000e+0 Identity = 376/516 (72.87%), Postives = 433/516 (83.91%), Query Frame = 3 Query: 72 RLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 R TL R Y S+++P TKMFING FV+S+TTEWIDL NPATN+ ++RVP CT EME AV + EAF++WSQ S+L RQQ MFKLQ LIK ++K+IAANIT EQGKTL DAEGDV+RGLQVVEH C +T+LQLGET+P ++KD+D +SY+ PLGV AGITPFNFPAMIPLWMFPL+LVCGNTM++KPSERDPGATM+LMEL E G P G VNV HG H++V FICDHP IRAISFVG D AG+ IYERGSKNGKRVQ N+GAKNHGV+MPDA KE T+NQL GAAFGAAGQRCMALSTAVFVGE +NWIP+++ RAK L V+ G PGADLGPVIS AK+RI L+ESG KEGAKI+LDGRN+KV G+E GNFVGPTILT+V PSM CY+EEIFGPVL+ L VDT+D+AI LIN+NPYGNGTAIFT +GATAR++TQ+I VGQVGVNVPIPVPLPMFSFTGSRGSFLGD NFYGK GVNF+TQLKTVTQLWR +D+ H AT P M Sbjct: 11 RTTLLRRFPIRGYASSSVPTTKMFINGQFVESKTTEWIDLMNPATNEPVTRVPVCTNDEMEAAVSAAKEAFKTWSQTSILTRQQSMFKLQNLIKENMKRIAANITEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSVSKDMDTLSYRIPLGVCAGITPFNFPAMIPLWMFPLALVCGNTMVIKPSERDPGATMILMELLQECGVPNGVVNVFHGTHESVRFICDHPDIRAISFVGSDTAGKFIYERGSKNGKRVQCNMGAKNHGVIMPDANKEYTLNQLTGAAFGAAGQRCMALSTAVFVGEAKNWIPELVERAKKLNVNAGHVPGADLGPVISPEAKQRICDLVESGVKEGAKIILDGRNIKVPGFEKGNFVGPTILTDVKPSMRCYREEIFGPVLLTLNVDTMDEAISLINSNPYGNGTAIFTTNGATARRYTQEIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDNNFYGKAGVNFYTQLKTVTQLWRAQDSTHAK--PATAMPVM 524
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Match: A0A131Y2Q8 (Putative methylmalonate semialdehyde dehydrogenase (Fragment) OS=Ixodes ricinus OX=34613 PE=2 SV=1) HSP 1 Score: 798.505 bits (2061), Expect = 0.000e+0 Identity = 373/508 (73.43%), Postives = 430/508 (84.65%), Query Frame = 3 Query: 96 LSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 L+R Y + A+P TKMFING FV+S+TTEW+DL NPATN++I+RVPKCT EM AV S EAF +WSQ S+L RQQ MFKLQ+LIK ++K++AAN+T EQGKTL DAEGDV+RGLQVVEH C +T+LQLGET+P I KD+D +SY+ PLGVTA ITPFNFPAMIPLWMFPL+LVCGNTM+LKPSERDPG TMMLMEL + G P G VNVIHG HDAV FICDHP IRAISFVG D+AG+ IYERGSKNGKRVQ N+GAKNHGV+MPDA KE T+NQL GAAFGAAGQRCMALSTAVFVGE +NWIP+++ RA+ LKV+ G PGADLGPVIS AKERI L+ESG +EGAK++LDGR + V GYE GNFVGPT+L +V P M CY+EEIFGPVL+ L VD++DDAI LIN+NPYGNGTAIFT +GATARK+TQ+I VGQVGVNVPIPVPLPMFSFTGSRGSFLGD NFYGK GVNF+TQLKTVTQLWR +D+ H +AT P M Sbjct: 14 LTRGY-AAAVPNTKMFINGQFVESKTTEWVDLKNPATNELITRVPKCTNAEMHEAVRSAKEAFRTWSQTSILPRQQSMFKLQQLIKENMKRLAANVTEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSITKDMDTMSYRIPLGVTACITPFNFPAMIPLWMFPLALVCGNTMVLKPSERDPGCTMMLMELLKQTGVPDGVVNVIHGTHDAVKFICDHPDIRAISFVGSDQAGKFIYERGSKNGKRVQCNMGAKNHGVVMPDANKEYTLNQLTGAAFGAAGQRCMALSTAVFVGEAKNWIPELVERARKLKVNAGHVPGADLGPVISPEAKERICDLVESGVQEGAKLLLDGRGIVVPGYEKGNFVGPTVLADVTPQMRCYQEEIFGPVLLTLSVDSMDDAIALINSNPYGNGTAIFTTNGATARKYTQEIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDANFYGKAGVNFYTQLKTVTQLWRTQDSTHSK--AATAMPVM 518
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Match: aldh1a2 (aldehyde dehydrogenase 1 family member A2 [Source:NCBI gene;Acc:103042804]) HSP 1 Score: 222.631 bits (566), Expect = 4.039e-65 Identity = 149/487 (30.60%), Postives = 243/487 (49.90%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN ++ DS + + NPAT + I V + K ++++AV++ AF W + +R + + KL +L++RD +A + + GK L + ++G ++ + + + G ++P L + EP+GV I P+NFP M+ W +L CGNT+++KP+E+ P + + L EAGFPPG VN++ G A I H I ++F G K G+ I E G N KRV +G KN ++ DA + + Q F +GQ C A + +FV E+ ++ + RAK V P + GP IS + R+ +ESG EGAK+ G+ + + G ++ PT+ +NV M +EEIFGPV ++ T+++ I+ NN YG A+FTN + A + + G V +N + P F S G+ G+ G+ +T++KT+T Sbjct: 36 IKHTKIFINNEWHDSLSGKTFSTYNPATGEKICDVQEADKADVDKAVKAARSAFSLSSEWRRMDSSDRGRLLSKLADLVERDRLYLATLESLDTGKPFLSSFFVDLQGTIKTLRYFAGWADKIHGTSIPTDGGYLSFTRH-EPIGVCGQIIPWNFPLMMMAWKLGPALCCGNTVVMKPAEQTPLTCLYMGSLIKEAGFPPGVVNILPGFGPTAGAGIASHMGIDKVAFTGSTKVGKLIQEAAGKSNLKRVTLELGGKNPNIIFADADLDLAVEQAHQGVFFNSGQCCTA-GSRIFVEESIYDEFVSRSVERAKRRIVGSPFDPTTEQGPQISAEQQRRVLEFVESGISEGAKLECGGK----AHFSKGFYIQPTVFSNVQDHMRIAREEIFGPVQQIMKFKTMEEVIERANNTEYGLTAAVFTNDISKAMAISTALQAGTVWINCFNALSCQCPFGGFKMS-----GNGRELGEYGLREYTEVKTIT 511
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Match: aldh1a2 (aldehyde dehydrogenase 1 family member A2 [Source:NCBI gene;Acc:103042804]) HSP 1 Score: 216.853 bits (551), Expect = 3.376e-63 Identity = 139/444 (31.31%), Postives = 225/444 (50.68%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 I TK+FIN ++ DS + + NPAT + I V + K ++++AV++ AF W + +R + + KL +L++RD +A + + GK L + ++G ++ + + + G ++P L + EP+GV I P+NFP M+ W +L CGNT+++KP+E+ P + + L EAGFPPG VN++ G A I H I ++F G K G+ I E G N KRV +G KN ++ DA + + Q F +GQ C A + +FV E+ ++ + RAK V P + GP IS + R+ +ESG EGAK+ G+ + + G ++ PT+ +NV M +EEIFGPV ++ T+++ I+ NN YG A+FTN + A + + G V +N Sbjct: 36 IKHTKIFINNEWHDSLSGKTFSTYNPATGEKICDVQEADKADVDKAVKAARSAFSLSSEWRRMDSSDRGRLLSKLADLVERDRLYLATLESLDTGKPFLSSFFVDLQGTIKTLRYFAGWADKIHGTSIPTDGGYLSFTRH-EPIGVCGQIIPWNFPLMMMAWKLGPALCCGNTVVMKPAEQTPLTCLYMGSLIKEAGFPPGVVNILPGFGPTAGAGIASHMGIDKVAFTGSTKVGKLIQEAAGKSNLKRVTLELGGKNPNIIFADADLDLAVEQAHQGVFFNSGQCCTA-GSRIFVEESIYDEFVSRSVERAKRRIVGSPFDPTTEQGPQISAEQQRRVLEFVESGISEGAKLECGGK----AHFSKGFYIQPTVFSNVQDHMRIAREEIFGPVQQIMKFKTMEEVIERANNTEYGLTAAVFTNDISKAMAISTALQAGTVWIN 473
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:NCBI gene;Acc:103032207]) HSP 1 Score: 212.231 bits (539), Expect = 2.013e-61 Identity = 156/493 (31.64%), Postives = 244/493 (49.49%), Query Frame = 3 Query: 117 TAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLL-----DAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 T I TK+FIN ++ S + I + NPAT I V + K +++ AVE+ A + +W + V R + + KL EL++RD +A + + GK L D EG + + + + + G+TMP + + + EP+GV I P+NFP ++ W +L CGNT+++KPSE P + + L EAGFPPG VN++ G + I H I ++F G + G+ I E +K N KRV +G KN ++ D+ + + + AF GQ C A S VFV E ++ + AK + + M P GP I++ E+I L+ESG +EGAK+ G L+ + G F+ PTI ++V M KEEIFGPV ++ + ++ I+ N+ YG A+FT S A + + G V VN + P F G + S G+ G+ + +T++K VT Sbjct: 27 TDIKHTKLFINNEWHSSAKGKTIPIFNPATGDKICEVEEADKADVDVAVEAARAAMKRGSAWRRMDVSGRGRLLHKLAELLERDRTLLATMESMDSGKPFLQSFFIDLEGSI----KTLRYYAGWADKIHGKTMP-VDDNFMCFTKHEPVGVCGAIIPWNFPLLMFTWKIAPALCCGNTVVIKPSELTPLTALHVGALIKEAGFPPGVVNIVPGFGPTSGAAIASHMGIDKVAFTGSVEVGQLIKEAAAKSNLKRVTLELGGKNPCIVFGDSDLQLAVQEAQKGAFYNQGQCCTAASR-VFVEERVYDEFVRLSVESAKKIVAGDPMDPRTSHGPQINQQQFEKILDLVESGKREGAKLECGGHALQ----DKGLFIQPTIFSDVKDHMRLAKEEIFGPVQCIMKFKSQEEVIERANSTHYGLAAAVFTRSVDRAMSVSSALEAGTVWVNCYNALHAQAP---FGGYKMS--GNGRELGEYALAEYTEVKAVT 504
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:NCBI gene;Acc:103032207]) HSP 1 Score: 209.149 bits (531), Expect = 2.000e-60 Identity = 153/493 (31.03%), Postives = 243/493 (49.29%), Query Frame = 3 Query: 117 TAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLL-----DAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 T + ++FIN ++ S + I + NPAT I V + K +++ AVE+ A + +W + V R + + KL EL++RD +A + + GK L D EG + + + + + G+TMP + + + EP+GV I P+NFP ++ W +L CGNT+++KPSE P + + L EAGFPPG VN++ G + I H I ++F G + G+ I E +K N KRV +G KN ++ D+ + + + AF GQ C A S VFV E ++ + AK + + M P GP I++ E+I L+ESG +EGAK+ G L+ + G F+ PTI ++V M KEEIFGPV ++ + ++ I+ N+ YG A+FT S A + + G V VN + P F G + S G+ G+ + +T++K VT Sbjct: 2 TFLSNIQLFINNEWHSSAKGKTIPIFNPATGDKICEVEEADKADVDVAVEAARAAMKRGSAWRRMDVSGRGRLLHKLAELLERDRTLLATMESMDSGKPFLQSFFIDLEGSI----KTLRYYAGWADKIHGKTMP-VDDNFMCFTKHEPVGVCGAIIPWNFPLLMFTWKIAPALCCGNTVVIKPSELTPLTALHVGALIKEAGFPPGVVNIVPGFGPTSGAAIASHMGIDKVAFTGSVEVGQLIKEAAAKSNLKRVTLELGGKNPCIVFGDSDLQLAVQEAQKGAFYNQGQCCTAASR-VFVEERVYDEFVRLSVESAKKIVAGDPMDPRTSHGPQINQQQFEKILDLVESGKREGAKLECGGHALQ----DKGLFIQPTIFSDVKDHMRLAKEEIFGPVQCIMKFKSQEEVIERANSTHYGLAAAVFTRSVDRAMSVSSALEAGTVWVNCYNALHAQAP---FGGYKMS--GNGRELGEYALAEYTEVKAVT 479
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Match: aldh9a1b (aldehyde dehydrogenase 9 family member A1 [Source:NCBI gene;Acc:103023076]) HSP 1 Score: 209.534 bits (532), Expect = 2.589e-60 Identity = 127/462 (27.49%), Postives = 230/462 (49.78%), Query Frame = 3 Query: 195 NPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETR--NWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSG--YEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN----VPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 PAT +V+ ++ C +++ AV+S A+ W + + + R + M + LI++ ++IA GK++ +A DV +E+ + G+ +PG + + +EPLGV GI +N+P I W ++ CGN+M+ KPS P + ++L E+ +AG P G +NV+ G + +C HP + +SF G G+ I E SK K V +G K+ ++ D+ E+ + + A F + GQ C + T VFV ++ +++ R K +++ + + +G ++S+ +++ +E KEGA+++ G + ++G ++ P +L N M C +EEIFGPV+ L DT ++ ++ N+ G +FT A + + + G +N P+ VP F G + S +G N G+ + F++QLKTV Sbjct: 57 EPATGRVLCQLQSCKAGQVDEAVKSACSAYAVWRKTAGMERARVMLEAARLIEKRREEIAEVEVVNNGKSITEARLDVDSARLCIEYFAGLATNLSGQHVQLPGGSFAY---TRREPLGVCVGIGAWNYPFQIAAWKSAPAIACGNSMVFKPSPVTPVSAVLLAEIYAQAGAPEGLLNVVQGAQETGTLLCHHPSVAKVSFTGSVPTGKKIMEMASKGVKPVTLELGGKSPLIIFEDSDLENAVRGALMANFLSQGQVC-SNGTRVFVHRKVLPQFVTEVVRRTKAIQIGDPLLEETRMGALVSRPHLDKVLGYVEQAKKEGARVLCGGELFTPADTKLKNGYYMMPCVLDNCKDDMTCVREEIFGPVMSILTFDTEEEVLQRANDTTMGLAAGVFTKDIQRAHRVIENLQAGSCFINNYNITPVEVP-----FGGFKTSGIGREN--GQVTIEFYSQLKTV 507
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh6a1 (aldehyde dehydrogenase 6 family, member A1 [Source:ZFIN;Acc:ZDB-GENE-030131-9192]) HSP 1 Score: 712.22 bits (1837), Expect = 0.000e+0 Identity = 333/498 (66.87%), Postives = 399/498 (80.12%), Query Frame = 3 Query: 126 PKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 P TK+FI+G FVDS T+EW+D+ NPATN+V++ VPK A ESC A+ WS+ SVL RQQ K Q+LIK ++K++A IT EQGKTL DAEGDV RGLQVVEHCCSIT+L LGET+P IA+D+D +Y+ PLGV AG+TPFNFPAMIPLWMFP++LVCGNT +LKPSER PG M+L L +AG P GT+NV+HGQHDAV F+CDHP I+AISFVG ++AG +I+ RGS NGKRVQ N+GAKNHGV+M DA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE R W+P+++ RAKNL+V+ G QPGADLGP+IS AK R+ L+ S KEGA+I+LDGR + V GYE GNFVGPTI+T V P M+CY EEIFGPVL+ LE D+LD+A+ +IN+NPYGNGTAIFTN+GATARKFT ++ VGQ+G+NVPIPVPLPMFSFTGSRGSF GD NFYGKQG F+TQLKTVT W+ EDA N PTM Sbjct: 4 PTTKLFIDGKFVDSTTSEWLDVHNPATNEVVTCVPK--------AAESCQRAYGPWSETSVLTRQQVFLKYQQLIKDNIKELAKVITKEQGKTLADAEGDVFRGLQVVEHCCSITSLVLGETLPSIARDMDSYTYRLPLGVCAGVTPFNFPAMIPLWMFPVALVCGNTFLLKPSERVPGTAMLLTRLLQDAGAPDGTLNVVHGQHDAVKFVCDHPVIKAISFVGSNQAGEYIHTRGSANGKRVQCNMGAKNHGVVMADANKENTLNQLVGAAFGAAGQRCMALSTAVMVGEAREWLPELVERAKNLRVNAGDQPGADLGPLISPEAKARVCELVGSAEKEGARIILDGRKVSVKGYESGNFVGPTIITGVKPHMKCYTEEIFGPVLLVLEADSLDEAVSVINSNPYGNGTAIFTNNGATARKFTHEVDVGQIGINVPIPVPLPMFSFTGSRGSFRGDVNFYGKQGFQFYTQLKTVTAQWKAEDATESV--PTVNMPTM 491
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004609.1 (pep scaffold:Pmarinus_7.0:GL479321:13801:23388:1 gene:ENSPMAG00000004155.1 transcript:ENSPMAT00000004609.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 197.208 bits (500), Expect = 1.985e-56 Identity = 129/463 (27.86%), Postives = 222/463 (47.95%), Query Frame = 3 Query: 183 IDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE-SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGE--TMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNL--KVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 D+ NPAT ++ R +++ AV+ EAFE SW S R Q++ + +IK +++A + GK + +A DV G Q +E+ + G+ +PG + + S +EPLGV GI +NFP I W +L CGN M+ KPS P + L E+ EAG PPG N++ G + +C H + +S G G + ++ + K V +G K+ ++ D ++ + + F + GQ C + +T VFV + ++ ++ R +++ + + +G +IS+ +R+ + ++ +EGAK+V G+ + + G F+ P +L M+ +EEIFGPV+ L DT ++ ++ N +G +FT A + + G +N V + M F G + S G N G V+++TQLKTV Sbjct: 59 FDVVNPATGGLLCRGQASGAVDVQAAVKDAREAFEGSWRGLSGSERSQHLLRASAIIKERREELAVMEVKDTGKPVYEARMDVDSGWQCLEYFAGLAPTIAGQHIQLPGGSF---MYSRREPLGVCVGIGAWNFPFQIACWKSAPALACGNAMVFKPSPLTPLTAVALAEIYTEAGLPPGLFNIVQGDGETGQLLCSHNDVAKVSCTGSVGTGVKVLQQTAPRIKPVTLELGGKSPLIVFSDCDLDNAVKAALMGNFLSQGQVC-SNATRVFVQRSVCERFLERLLDRVSAIRIGDPQRDSTTMGALISQSHLDRVLAYVQRAVQEGAKLVCGGKKYVPEDPSLKGGFFMTPCVLAECRDDMQAVREEIFGPVMAVLAFDTEEEVLQRANATDFGLAAGVFTKDLTRAHRVIAALQAGSCYINNYNVVLMEM-PFGGYKMSGFGREN--GMATVDYYTQLKTV 514
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh5a1 (aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) [Source:ZFIN;Acc:ZDB-GENE-070228-2]) HSP 1 Score: 172.17 bits (435), Expect = 4.036e-48 Identity = 109/379 (28.76%), Postives = 184/379 (48.55%), Query Frame = 3 Query: 312 NRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV----NFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARA--KNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 R + + E+I ++ +++A IT+E GK ++ G+V G +E G+ +P A D + S +P+GV A ITP+NFP + +L G T ++KP+E P + + L +L VEAG PPG +NV+ V +C HP + ISF G G+ + KRV +G ++ A ++ + L+ + F +GQ C+ + + + +A A L+V G G LGP+I++HA E++ + +GA++V+ G + G+F PT+L +V P+M C +EE FGP+ ++ T ++AI L N+ G F+ A + ++ + VG VG N Sbjct: 2 ERGALLKRWYEVILQNRQELAQLITAESGKPQQESLGEVSYGAAFLEWFGEEARRAYGQIIPSAAPDRRMFSMYQPVGVAAMITPWNFPVAMITRKVGAALAAGCTAVVKPAEDTPLSALALAQLAVEAGLPPGVLNVVPCSRANVAAVGELLCTHPSVSKISFTGSTATGKVLMAHAVGTVKRVSMELGGHAPFIVFESADLDAAVRGLLSSKFRFSGQTCVCPNRMLVQESVHDAFVSRLAHAVSTQLRVGPGADTGNTLGPLINEHALEKVERHVVDAVSQGARVVVGGARHALG----GSFFQPTVLADVTPNMLCAREETFGPLAPIIKFKTEEEAIALANSTAMGLAGYFFSRDVAQVWRVSEALEVGMVGAN 376
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:ZFIN;Acc:ZDB-GENE-100426-6]) HSP 1 Score: 173.711 bits (439), Expect = 6.778e-47 Identity = 134/498 (26.91%), Postives = 238/498 (47.79%), Query Frame = 3 Query: 105 NYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES--WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTL-LDAEGDVMRGLQVVEHCCSITNLQLGETMP-GIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV--NFICDHPKIRAISFVGGDKAGRHIYER-GSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEV--DTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 N L+ IP + FI+G FVD+ T++ D NP VI +V + +++ AV + AFES W + + +R + ++KL +L++ +++A T + G L + V +Q + + G T+P A+ +++ +EP+GV + P+N+P M+ W L GNT++LKP++ P + EL +AGFP G +N+I G ++ + +HP IR + F G G+ I + + N K+V +G K+ ++ D + + + A F G+ C+A + +FV E+ ++ ++ K +KV + + D GP + E++ E G KEGA +V GR + F P++ T V M +EE FGP+++ + +D + NN +G + +FT + A + ++ G V +N V P F G + S G G++ +N + + K VT Sbjct: 202 NNLTVRIPH-QCFIDGKFVDADTSKTYDTVNPTDGSVICKVAFASVADVDEAVAAAKRAFESGEWGRMNPRDRGRLLYKLADLMEEHQEELATIETLDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIHGTTIPINQARPNRNLTFTKREPIGVCGIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAAKAGFPKGVINIIPGSVGSIVGQRMSEHPHIRKLGFTGSTPIGKQIMKSCATSNLKKVSLELGGKSPLIIFNDCDIDKAVRMGMSAVFFNKGENCIA-AGRLFVEESIHDEYVRRVVEEIKKMKVGDPLDRSTDHGPQNHRAHMEKLVEYCEVGVKEGATLVHGGRQVPRPEV----FANPSVFTGVEDHMYIAQEESFGPIMVISKFPDGDIDGVLARANNTEFGLASGVFTRDISKALYVSDQLEAGTVFINTYNKTDVAAP---FGGFKQSGFGKD--LGEEALNEYLRTKAVT 688
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh8a1 (aldehyde dehydrogenase 8 family, member A1 [Source:NCBI gene;Acc:447801]) HSP 1 Score: 153.295 bits (386), Expect = 1.018e-40 Identity = 137/477 (28.72%), Postives = 220/477 (46.12%), Query Frame = 3 Query: 141 FINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQ-HDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIAR-AKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVL-DGRN--LKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 +ING+FV S+T +D P+T V RVP + E+ AVE+ AF +W+ RS R + + +L ELI+ L+++A + +QGKT+ A D+ R S E + + P+GV I+P+N P + W ++ GNT++ KPSE ML L EAG PPG VNV+ G A + HP + AISF G I R + + KR+ +G KN V+ DA ++ + V ++F + +A+F P R K KV +++GP+ISK ++ +E ++G +++ +G + L + G F+ PT++T V +EEIFGPV+ + D+A+ N YG +++ A + +++ G V N + L + F G + S +G K FFT +KT+T Sbjct: 13 YINGEFVASETH--VDSFEPSTGNVYCRVPDSGEAEVNAAVEAAKRAFPAWAARSPQERGRILTRLAELIESRLEELAIAESHDQGKTVEHARTVDIPRAAYNFRFFASAVQHYTTECTQADHVGCMHYTVRSPVGVVGLISPWNLPLYLLTWKIAPAIALGNTVVAKPSELTSVTAWMLCMLLREAGVPPGVVNVVLGTGQKAGAALVGHPDVPAISFTGSTATACDITVRSALHCKRLSLELGGKNPAVIFADADLDACVATTVRSSFANQTGHVPSSLSAIFSHSVVVQCPRRFFRTTKAWKVGPPDDFTSNMGPLISKEHLAKVRGYVELAERDGGQVLCGEGVDPLLLPPRCQGGYFLAPTVITGVPDDSPAMQEEIFGPVVCVSPFEDEDEAVTRSNGVRYGLAAVVWSRDVARVHRVAKRLQAGIVWTNCWLIRELNL-PFGGMKASGIGREG--AKDSFEFFTDVKTIT 484
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Match: ALD4 (Mitochondrial aldehyde dehydrogenase; required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed; can substitute for cytosolic NADP-dependent aldehyde dehydrogenase when directed to the cytosol; human homolog ALDH2 can complement yeast ald4 mutant [Source:SGD;Acc:S000005901]) HSP 1 Score: 209.534 bits (532), Expect = 3.536e-61 Identity = 125/438 (28.54%), Postives = 227/438 (51.83%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE--SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV-NFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 T +FIN FV S+ + ++ NP+T + I + + + ++E AV++ AF SW+ ++R + +++L ELI++D IA+ T + GK + + GDV + ++ + ++ M + + ++PLGV I P+NFP ++ W +LV GNT++LK +E P + + + + +AG PPG +N++ G V I +HPKI+ ++F G GRHIY+ + K+V +G K+ ++ DA + + ++ + +G+ C A + V+V E+ +I + A ++++KV + G S+ +I ++ G EGA ++ G L GY F+ PT+ +V M KEEIFGPV+ + + D+ I + N++ YG I T++ TA K +++ G V +N Sbjct: 45 TGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFAD-KIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCA-GSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGY----FIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWIN 476
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Match: ALD5 (Mitochondrial aldehyde dehydrogenase; involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed [Source:SGD;Acc:S000000875]) HSP 1 Score: 207.994 bits (528), Expect = 1.169e-60 Identity = 128/437 (29.29%), Postives = 218/437 (49.89%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES-WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV-NFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 T +FING+FV S+ + D+ NP+ + I+ V K + +++ AV + +AFE+ WS R + +F L +L+++ + +AA + + GK+L A GDV + + C + G + K+ S KEPLGV I P+NFP ++ W +L GNT++LKP+E P + + +LC EAG P G VN++ G V + HP ++ I+F G GRHI + + K+V +G K+ ++ DA + + + F +G+ C A + +++ +T + + ++LKV + G S +I ++ EGA++V G GY FV PT+ +V M KEE+FGP++ + T+D+ I + N++ YG I TN A ++++ G V +N Sbjct: 44 TGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGNVID-TGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCA-GSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGY----FVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWIN 474
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Match: ALD2 (Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p [Source:SGD;Acc:S000004780]) HSP 1 Score: 200.675 bits (509), Expect = 4.597e-58 Identity = 152/504 (30.16%), Postives = 240/504 (47.62%), Query Frame = 3 Query: 108 YLSTAIPKTK--------MFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES-WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTL-LDAEGDVMRGLQVVEHCC-SITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV-NFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKN-LKVSEGMQPGAD---LGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVP----IPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 Y IP+ K +FIN +F S + I+ NPAT + I+ + ++++AV++ AF++ WS+ S R Y+ L +LI+ + +AA T + GK +A+GD+ + LQ+ + S G T+P + + + K P GV A I P+N+P + W +L GNT+I+KP+E + + L +AGFPPG VN++ G V + H I ISF G K G + E G N K V G K+ ++ DA + I+ + F +GQ C A ++ V+V + ++ AK V+ P + +GPVIS +RI S IE G +E + + G + G F+ PTI T+V + + ++EIFGPV++ + DDA+KL N+ YG +A+FT A F + I G V +N + VP F +G G+ GV+ + Q K V Sbjct: 5 YTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIP-LTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTA-NSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAK-GYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGREL-------GQSGVDTYLQTKAV 498
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Match: ALD3 (Cytoplasmic aldehyde dehydrogenase; involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose [Source:SGD;Acc:S000004779]) HSP 1 Score: 193.356 bits (490), Expect = 2.875e-55 Identity = 153/504 (30.36%), Postives = 243/504 (48.21%), Query Frame = 3 Query: 108 YLSTAIPKTK--------MFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES-WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTL-LDAEGDVMRGLQVVEHCC-SITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAV-NFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKN-LKVSEGMQPGAD---LGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV----PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTV 1550 Y IP+ K +FIN +F S + I+ NPAT + I+ + ++++AV++ AF++ WS+ S R Y+ L +LI+ + +AA T + GK +A+ D+ + +++ + ++ +GET+P + + + K P GV A I P+N+P + +L GNT+I+KP+E + + L +AGFPPG VNVI G V + H I ISF G K G + E G N K + G K+ ++ DA + I + F +GQ C A ++ V+V + ++ AK V+ P + +GPVIS +RI S IE G KE + + G + G F+ PTI T+V + + ++EIFGPV++ + DDA+KL N+ YG +A+FT A F + I G V +N VP F +G G GDT GV+ + Q+K+V Sbjct: 5 YTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIP-LTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTA-NSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAK-GYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGI-GRESGDT------GVDNYLQIKSV 498
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Match: ALD6 (Cytosolic aldehyde dehydrogenase; activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress [Source:SGD;Acc:S000005982]) HSP 1 Score: 185.652 bits (470), Expect = 1.450e-52 Identity = 123/442 (27.83%), Postives = 214/442 (48.42%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFES--WSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNF-ICDHPKIRAISFVGGDKAGRHI-YERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAK-----NLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 T +FIN F+ +Q + + +P+T + V T ++E A+E AF W+ + R + + KL + ++ + +++ + GKTL A GDV + + + + G T+ ++ + EP+GV I P+NFP M+ W +L GN ILKP+ P + LC + G P G VN++ G V + + P+IR ++F G + G+ + + N K++ +G K+ ++ DA + T+ LV F AGQ C + + ++V E +++A K +KV G + ++ + I + I+ G KEGAKI+ G + GY F+ PT+ +VN M KEEIFGPV+ + TL++ +++ N++ +G G+ I T S +T K + + G V +N Sbjct: 26 TGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTL-EPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSS-GSRIYVQE--GIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGY----FIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWIN 459
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Match: EDO49572 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP1]) HSP 1 Score: 748.429 bits (1931), Expect = 0.000e+0 Identity = 348/506 (68.77%), Postives = 426/506 (84.19%), Query Frame = 3 Query: 102 RNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 + Y S IP TKMFING F DS++++WIDL NPATN+VI+RVP+CT+ EM+ AV++ A AF SWS+ SVL RQQ MF LQ LIK+++K++A NIT EQGKTL DAEGDV+RGLQVVEH CSIT+LQ+GETMP + KD+D SY+ PLGV AGITPFNFPAMIPLWMFP+++VCGNT ++KPSERDPGATMML+++ +AG P G VN IHG +AV FIC++P I+AISFVG D+AG++IYE GSK+GKRVQ+N+GAKNHGV+MPDA KE+TINQLVGAAFGAAGQRCMALSTA+FVGET+ WIP+I+ +AK LKVS G QPGADLGP+IS AK+R L++SG ++GA + LDGR++ V GYE+GNFVGPT+L+NV P M CYKEEIFGPVL+ L DTL+DA+++IN NPYGNGTAIFT SGA ARKF QK +VGQ+G+NVPIPVPLPMFSFTGSRGSFLGD++FYGKQG+NF+T KT+T LWR+ED+ + NFP M Sbjct: 26 KRYSSDGIPTTKMFINGQFSDSKSSKWIDLHNPATNEVITRVPECTQDEMQAAVDAAAAAFLSWSESSVLTRQQIMFNLQHLIKKNMKELAKNITLEQGKTLADAEGDVLRGLQVVEHTCSITSLQMGETMPSVTKDMDTYSYRVPLGVCAGITPFNFPAMIPLWMFPMAMVCGNTYVIKPSERDPGATMMLLKMAQDAGVPDGVVNCIHGAREAVKFICENPTIKAISFVGSDQAGKYIYETGSKHGKRVQSNMGAKNHGVIMPDANKENTINQLVGAAFGAAGQRCMALSTAIFVGETKEWIPEIVEKAKQLKVSAGDQPGADLGPMISPQAKKRACDLVQSGVEQGASLDLDGRDIVVKGYENGNFVGPTVLSNVTPEMTCYKEEIFGPVLVALNADTLEDAVEIINRNPYGNGTAIFTKSGAIARKFAQKANVGQIGINVPIPVPLPMFSFTGSRGSFLGDSHFYGKQGINFYTGTKTITSLWRDEDSV--PQKVQANFPIM 529
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Match: EDO45538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSB4]) HSP 1 Score: 217.624 bits (553), Expect = 5.995e-64 Identity = 154/484 (31.82%), Postives = 237/484 (48.97%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 I TK+FIN +FVD + + NP T + I + + K ++++AV++ EAF+ +W R + ++KL +LI RD+ +A+ T + GK D+ GD+ + + G+T+P + + EP+G+ ITP+NFP + +L CGN +ILKP+E+ P + L EAGFP G VNVI G A I H I +SF G + GR I E +K N KR+ +G K+ ++ D+ + + A F GQ C A S FV +T ++ + RAK V + + GP I + ++I LIESG KEGAK+ G G+ F+ PT+ ++V M KEEIFGPV ++ ++D+ I+ NN YG +FT + TA + + G V +N P F G + S G +G+ GV + ++KTVT Sbjct: 13 IKYTKLFINNEFVDCTSGKVFPTINPTTGEKICDISEGDKEDVDKAVKAAKEAFKLGSAWRTMDASMRGKLLYKLAQLIDRDIAYLASLETIDSGKLFSDSVGDMQSSANCFRYYAGWADKVTGKTIPADGPYF-VYTRHEPVGLVGAITPWNFPLNMASVKIAPALACGNVVILKPAEQTPLTALYFCALVKEAGFPAGVVNVIPGYGPTAGAAITTHLDIDKVSFTGSTEVGRLIQEASAKSNLKRLTLELGGKSPNIVFADSDMDYAVEMAHEALFFNQGQCCSAGSR-TFVQDTIYDEFVKKSVKRAKARTVGDPFD-SVEQGPQIDQEQFDKIMDLIESGKKEGAKMQCGGARHGNKGF----FIQPTVFSDVTDDMRIAKEEIFGPVQQLIKFKSVDEVIERANNTTYGLAAGVFTKNIDTAIAVSSGLRAGTVWINC-YECGAPQAPFGGYKMSGYGRE--WGEYGVLPYCEVKTVT 486
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Match: EDO36183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJA5]) HSP 1 Score: 196.823 bits (499), Expect = 1.371e-56 Identity = 142/440 (32.27%), Postives = 216/440 (49.09%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVG 1415 + T++FIN +FVDS + + NPAT + I V + K +++ AV + EAF+ W R +++KL +L +RD +A + + GK + +A+ DV + + + G+T+P D +Y EP+GV ITP+NFP ++ +L CG +ILKP+E+ P + L L EAGFP G VNV+ G A I H I ISF G + GR I E +K N KRV +G K+ ++ DA + + F GQ C A T +FV E+ ++ +ARAK V + ++ GP + + +I LIESG ++GAK+ G GY FV PT+ + V M KEEIFGPV+ L+ + +++ I+ N+ YG A+F+ A I G Sbjct: 6 VKYTQLFINNEFVDSVSGKTFPTLNPATEEKICDVSEADKADVDIAVAAAKEAFKLGSVWRTMDASARGHFLYKLADLCERDADYLARLESYDGGKVINEAKIDVQGMISCFRYYAGWADKVTGKTIPA---DGPFFTYTRHEPVGVVGAITPWNFPLLMEGLKLAPALACGCVVILKPAEQTPLTALYLASLVKEAGFPTGVVNVLPGYGPTAGAAISSHMGIDKISFTGSTEVGRLIQETAAKSNLKRVTLELGGKSPNIVFADADLDWAVEMSCLGLFINQGQCCCA-GTRIFVEESIHDEFVRQCVARAKARVVGDPLEEKTVQGPQVDEEQFNKILGLIESGKQQGAKVECGGGRHGNKGY----FVEPTVFSGVQDDMRIAKEEIFGPVMQILKFNEINEVIRRANDTTYGLAGAVFSKDIDKALMVAHSIQAG 437
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Match: EDO47653 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLS5]) HSP 1 Score: 195.282 bits (495), Expect = 1.813e-55 Identity = 144/487 (29.57%), Postives = 239/487 (49.08%), Query Frame = 3 Query: 123 IPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYER--GSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALS-TAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 I ++FIN FV+S + + NP+T +VI V + K +++ AV++ AF+ W +R + + +L +LI+RD +A+ T + GK D+ D+ ++ + + G+T+P + + EP+GV + P+NFP ++ W +L CGNT+++KP+E+ P + + L EAGFP G VN++ G A I H + I+F G + G HI ++ G+ N K V +G K+ +++ D+ + ++ A F GQ C A S T V G ++ + RAKN V GP + +I +LIESG KEGAK+ + G GY F+ PT+ ++V +M +EEIFGPV+ ++D I+ N YG ++ T + A + + VG V VN + P F G + S +G G+ G+ ++++KTVT Sbjct: 40 IKYNQVFINNQFVNSVSGKTFQTFNPSTGEVICDVAEGDKHDVDIAVKAAQSAFKLGSPWRTMDASDRGRLLNRLADLIERDKAYLASLETLDNGKPYNDSFNVDLEFTIKCYRYYAGWADKIHGKTIP-LDGSFFCYTRHEPVGVVGQVIPWNFPLLMQAWKLGPALACGNTVVMKPAEQTPLTALYVASLIAEAGFPEGVVNIVPGFGPTAGGAIASHMDVDKIAFTGSTEVG-HIIQQSAGASNLKNVTLELGGKSPNIVLADSDVDFAVDMSHFALFFNQGQCCCAGSRTFVQEGIYDEFVEKSVQRAKNRVVGNPFDLKTQQGPQVDGEQMTKILNLIESGRKEGAKLEVGGDRAGDKGY----FIQPTVFSDVQDNMRIAQEEIFGPVMQIFRFKDMNDIIERANKTTYGLAGSVMTKNLENALMLSNSLRVGTVWVNCYDALSAQAP---FGGYKMSGVGRE--LGEYGLQQYSEVKTVT 515
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Match: EDO34362 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPJ4]) HSP 1 Score: 193.356 bits (490), Expect = 2.926e-55 Identity = 128/465 (27.53%), Postives = 216/465 (46.45%), Query Frame = 3 Query: 189 LPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKV-SGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN----VPIPVPLPMFSFTGSRGSFLGDTNFYGKQG----VNFFTQLKTV 1550 + +P+T + V K E++RAV S +AF++WS S R + + L+++ + IA + GK +A DV V+E+ + G+ + + + +EPLGV GI +N+P W ++ CGNT++ KPS P + L ++ EAG PPG VN+I G + + P + +SF G G+ I + K V +G K+ ++ DA + ++ + A F + GQ C + T VFV ++ ++ ++ R KN++V + M P +G +IS ++ ++ G EGAK++ G L + G ++ P ++ M KEEIFGPV+ L T ++A+ NN +G IFT A + + G +N P+ VP + +G +G++G V +TQLKTV Sbjct: 3 ITDPSTGHISCEVKGSGKTEVKRAVLSARKAFKTWSVLSGSERGRILGDASRLVRKRREDIAKVEVHDNGKPFHEALWDVDNVADVLEYYAGVAPTLSGQHVQ-LPNGSFAYTRREPLGVVGGIGAWNYPIQTACWKIAPAIACGNTIVYKPSPLTPMNAVALADILTEAGVPPGVVNIIQGGGETGEMLSKDPNVAKVSFTGSVPTGQKIMASCADGIKHVTLELGGKSPLIIFKDADMANAVSGALMANFLSQGQVC-SNGTRVFVEDSIKDEFLEKVVERTKNIRVGDPMAPDTQMGAMISSAHLNKVLDYVQIGKDEGAKVLCGGERLHLPEPLTSGYYMSPCVMAECTDDMTVVKEEIFGPVMTVLTFQTEEEAVTRANNTTFGLAGGIFTRDLNRAHRVIGSLQAGTCWINSFNITPVEVPFGGYKMSG-----------FGREGGTAAVEHYTQLKTV 454
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Match: aldh6a1 (aldehyde dehydrogenase 6 family member A1 [Source:NCBI gene;Acc:101161931]) HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0 Identity = 347/502 (69.12%), Postives = 417/502 (83.07%), Query Frame = 3 Query: 114 STAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 S+++P K+FI+G FV+S+T+EW+++ NPATN+VI+RVPK T EM A ESC+ +F SWS+ S L RQQ + Q+LIK ++K++A IT EQGKTL DAEGDV RGLQVVEH CSIT+L LGET+P I KD+D +Y+ PLGV AGI PFNFPAMIPLWMFP+ +VCGNT +LKPSER P TM+L +L +AG P GT+N+IHGQHDAVNFICDHP I+AISFVG ++AG +IYERGS+NGKRVQ+N+GAKNHGV+MPDA KE+T+NQLVGAAFGAAGQRCMALSTAV VGE RNW+P+++ R K L+V+ G QPGADLGP+IS AKER+ SLI+SG EGAK+VLDGRN+KV GYE+GNFVGPTI++ V P M+CY EEIFGPVLI LE DTLDDAI+L+N NPYGNGTAIFT +GATARK+T ++ VGQVGVNVPIPVPLPMFSFTGSRGSF GDTNFYGKQG+ F+TQ+KTVT W+ EDA K A PTM Sbjct: 24 SSSVPTVKLFIDGKFVESKTSEWLEIHNPATNEVIARVPKATHEEMLAAAESCSRSFHSWSETSALTRQQVFLRYQQLIKDNIKELAKAITVEQGKTLADAEGDVFRGLQVVEHACSITSLMLGETLPSITKDMDTYTYRLPLGVCAGIAPFNFPAMIPLWMFPMGMVCGNTYLLKPSERVPTCTMLLAKLLQDAGAPDGTLNIIHGQHDAVNFICDHPAIKAISFVGSNQAGEYIYERGSRNGKRVQSNMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEARNWLPELVERTKALRVNAGDQPGADLGPLISPQAKERVCSLIQSGVDEGAKLVLDGRNVKVKGYENGNFVGPTIISGVTPEMKCYTEEIFGPVLIVLEADTLDDAIRLVNKNPYGNGTAIFTTNGATARKYTHEVDVGQVGVNVPIPVPLPMFSFTGSRGSFRGDTNFYGKQGIQFYTQIKTVTSQWKAEDATL--KSPAVTMPTM 523
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Match: ENSORLT00000045168.1 (methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Source:NCBI gene;Acc:101158320]) HSP 1 Score: 749.199 bits (1933), Expect = 0.000e+0 Identity = 343/502 (68.33%), Postives = 421/502 (83.86%), Query Frame = 3 Query: 114 STAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 S+++P TK+FI+G FV+S ++EW+D+ NPATN+V+ RVPK T+ EM AV+SC+ +F+SWS+ S+L RQQ + Q+LIK ++K+++ IT EQGKTL DAEGDV RGLQVVEH CSIT+L LGET+P I KD+D +Y+ P+GV AGI PFNFPAMIPLWMFP+ +VCGNT ++KPSER PG TM+L +L +AG P GT+N+IHGQH AVNFICDHP I+AISFVG ++AG +IYERGSKNGKRVQ+N+GAKNHGV+MPDA KE+TINQLVGAAFGAAGQRCMALSTA+FVGE+R+W+P+++ R+K L V+ G QPGAD+GP+IS AK R+ LI+SG EGAK++LDGRN++V GYE+GNFVGPT+LTNV+P M CYKEEIFGPVLI LEVDTLD+AI LIN NPYGNGTAIFT +GATARK+T + VGQ+GVNVPIPVPLPMFSFTGSRGSF GDTNFYGKQG+ F+TQ+KTVT W+ EDA S A PTM Sbjct: 26 SSSVPTTKLFIDGKFVESNSSEWLDVHNPATNQVVGRVPKATQEEMLAAVDSCSRSFQSWSETSILTRQQVFLRYQQLIKDNIKELSKIITLEQGKTLADAEGDVFRGLQVVEHACSITSLMLGETLPSITKDMDTYTYRMPIGVCAGIAPFNFPAMIPLWMFPIGMVCGNTYLMKPSERVPGCTMLLAKLLQDAGAPDGTLNIIHGQHAAVNFICDHPAIKAISFVGSNQAGEYIYERGSKNGKRVQSNMGAKNHGVVMPDANKENTINQLVGAAFGAAGQRCMALSTAIFVGESRDWLPELVERSKLLHVNAGDQPGADVGPLISPEAKARVEHLIQSGVDEGAKLLLDGRNVRVKGYENGNFVGPTVLTNVSPEMTCYKEEIFGPVLIVLEVDTLDEAIALINRNPYGNGTAIFTTNGATARKYTHGVDVGQIGVNVPIPVPLPMFSFTGSRGSFRGDTNFYGKQGIQFYTQIKTVTSQWKAEDATVSSP--AVTMPTM 525
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Match: ENSORLT00000011823.2 (methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Source:NCBI gene;Acc:101158320]) HSP 1 Score: 457.218 bits (1175), Expect = 9.411e-158 Identity = 207/308 (67.21%), Postives = 257/308 (83.44%), Query Frame = 3 Query: 120 AIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNL 1043 AIP TK+FI+G FV+S ++EW+D+ NPATN+V+ RVPK T+ EM AV+SC+ +F+SWS+ S+L RQQ + Q+LIK ++K+++ IT EQGKTL DAEGDV RGLQVVEH CSIT+L LGET+P I KD+D +Y+ P+GV AGI PFNFPAMIPLWMFP+ +VCGNT ++KPSER PG TM+L +L +AG P GT+N+IHGQH AVNFICDHP I+AISFVG ++AG +IYERGSKNGKRVQ+N+GAKNHGV+MPDA KE+TINQLVGAAFGAAGQRCMALSTA+FVGE+R+W+PD NL Sbjct: 71 AIPTTKLFIDGKFVESNSSEWLDVHNPATNQVVGRVPKATQEEMLAAVDSCSRSFQSWSETSILTRQQVFLRYQQLIKDNIKELSKIITLEQGKTLADAEGDVFRGLQVVEHACSITSLMLGETLPSITKDMDTYTYRMPIGVCAGIAPFNFPAMIPLWMFPIGMVCGNTYLMKPSERVPGCTMLLAKLLQDAGAPDGTLNIIHGQHAAVNFICDHPAIKAISFVGSNQAGEYIYERGSKNGKRVQSNMGAKNHGVVMPDANKENTINQLVGAAFGAAGQRCMALSTAIFVGESRDWLPDSYGSFLNL 378
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Match: aldh1a2 (aldehyde dehydrogenase 1 family member A2 [Source:NCBI gene;Acc:100049450]) HSP 1 Score: 217.624 bits (553), Expect = 2.931e-63 Identity = 152/484 (31.40%), Postives = 242/484 (50.00%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 TK+FIN ++ S + + + NPAT + I V + K ++++AV++ AF W + R + + KL +L++RD +A + GK L ++G ++ + + + G ++P + L Y EP+GV I P+NFP M+ W +L CGNT++LKPSE P + + L EAGFPPG VN++ G A I H I ++F G + G+ I E G N KRV +G KN ++ DA + + Q F AGQ C A + ++V E ++ + RAK V P + GP IS+ + R+ I+SG +EGAK+ G+ L + G+ F+ PT+ ++V M KEEIFGPV ++ T+++AI+ NN+ YG A+FT A + + G V VN + P F G + S G+ G+ G+ + ++KT+T Sbjct: 38 TKIFINNEWHVSVSGKVFPVYNPATGEQICEVQEADKADVDKAVQAARLAFSLGSVWRRMDASERGKLLAKLADLVERDSVYLATIESLNSGKPFLPTLFVDLQGTIKTLRYFAGYADKIHGTSIPMDGEYLTFTRY-EPIGVCGQIIPWNFPLMMAAWKLAPALACGNTVVLKPSEETPLTCLYVAALVKEAGFPPGVVNILPGFGPTAGAAIASHMGIDKVAFTGSTEVGKLIQEAAGRSNLKRVTLEMGGKNPNIIFADADLDLAVEQAHQGVFFNAGQCCTA-GSRIYVEEPIYDEFVRRSVERAKRRIVGSPFDPTTEQGPQISREHQNRVLEYIQSGIQEGAKLECGGKALGLKGF----FIEPTVFSDVKDDMRIAKEEIFGPVQQIMKFKTVEEAIERANNSDYGLTAAVFTTDINKAMTVSTAMQAGTVWVNCFNALSTQCP---FGGYKMS--GNGRELGESGLKEYLEIKTIT 510
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Match: aldh1a2 (aldehyde dehydrogenase 1 family member A2 [Source:NCBI gene;Acc:100049450]) HSP 1 Score: 213.772 bits (543), Expect = 3.787e-62 Identity = 142/441 (32.20%), Postives = 223/441 (50.57%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRG-LQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHG-QHDAVNFICDHPKIRAISFVGGDKAGRHIYE-RGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGE--TRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVN 1430 TK+FIN ++ S + + + NPAT + I V + K ++++AV++ AF W + R + + KL +L++RD +A + GK L ++G ++ + + + G ++P + L Y EP+GV I P+NFP M+ W +L CGNT++LKPSE P + + L EAGFPPG VN++ G A I H I ++F G + G+ I E G N KRV +G KN ++ DA + + Q F AGQ C A + ++V E ++ + RAK V P + GP IS+ + R+ I+SG +EGAK+ G+ L + G+ F+ PT+ ++V M KEEIFGPV ++ T+++AI+ NN+ YG A+FT A + + G V VN Sbjct: 38 TKIFINNEWHVSVSGKVFPVYNPATGEQICEVQEADKADVDKAVQAARLAFSLGSVWRRMDASERGKLLAKLADLVERDSVYLATIESLNSGKPFLPTLFVDLQGTIKTLRYFAGYADKIHGTSIPMDGEYLTFTRY-EPIGVCGQIIPWNFPLMMAAWKLAPALACGNTVVLKPSEETPLTCLYVAALVKEAGFPPGVVNILPGFGPTAGAAIASHMGIDKVAFTGSTEVGKLIQEAAGRSNLKRVTLEMGGKNPNIIFADADLDLAVEQAHQGVFFNAGQCCTA-GSRIYVEEPIYDEFVRRSVERAKRRIVGSPFDPTTEQGPQISREHQNRVLEYIQSGIQEGAKLECGGKALGLKGF----FIEPTVFSDVKDDMRIAKEEIFGPVQQIMKFKTVEEAIERANNSDYGLTAAVFTTDINKAMTVSTAMQAGTVWVN 472
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Match: SMESG000039266.1 (SMESG000039266.1) HSP 1 Score: 1087.4 bits (2811), Expect = 0.000e+0 Identity = 521/523 (99.62%), Postives = 522/523 (99.81%), Query Frame = 3 Query: 51 MFYIASKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 1619 MFYI SKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQ+IHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM Sbjct: 1 MFYIVSKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFESWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEGDVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHDAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQRIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVTQLWREEDAEHDSKGSATNFPTM 523
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Match: SMESG000016195.1 (SMESG000016195.1) HSP 1 Score: 215.698 bits (548), Expect = 9.058e-63 Identity = 153/482 (31.74%), Postives = 244/482 (50.62%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNG-KRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 TK+FIN ++ DS + + NPAT + I +V + K ++++AV + +AF+ W + +R M+KL +LI+RD +AA T + GK + A DV ++ E+ + G+ +P I D + EP+GV I P+NFP ++ W +L GNT++LK +E+ P + L EAGFPPG VN++ G A + HPK+ I+F G + G+ I + ++N KR+ +G K+ ++ DA ++ + A F GQ C A + ++V E ++ ++A AK+ KV D GP I + +I I+SG EGA++ G+ + G+ F+ PTI T V SM KEEIFGPV+ ++ ++ I NNN YG +IFT + TQ + G V VN V F G + S +G G+ G++ +T++K VT Sbjct: 41 TKIFINNEWHDSVSKKTFPTKNPATGQDICQVAEGGKEDIDKAVTAANKAFQLGSPWRKMDAADRGSLMYKLAQLIRRDADYLAALETLDSGKPVSIARAADVELTIKCYEYYAGWADKNHGKVIP-IRGDYIGFTRHEPVGVCGQIIPWNFPLLMQAWKLAPALSMGNTVVLKTAEQTPLTANYVASLAAEAGFPPGVVNIVPGMGPTAGAALVTHPKVDKIAFTGSTEVGQIISKHCNENNIKRLTLELGGKSPNIVFADADFDNAVKTSYFALFFNMGQCCCA-GSRIYVEEKIYDKFVEAMVAEAKS-KVVGNPFDNVDQGPQIDEEQMNKILGFIDSGKSEGAQMCTGGKQIGSKGF----FIEPTIFTKVEDSMRIAKEEIFGPVMQIMKFKDTNEVIARANNNEYGLAASIFTQDIDKSLHVTQSLRAGTVWVNC-YDVFDAAAPFGGYKSSGVGRE--LGEYGLSNYTEVKMVT 512
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Match: SMESG000016195.1 (SMESG000016195.1) HSP 1 Score: 215.698 bits (548), Expect = 1.085e-62 Identity = 153/482 (31.74%), Postives = 244/482 (50.62%), Query Frame = 3 Query: 132 TKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE---SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTLLDAEG-DVMRGLQVVEHCCSITNLQLGETMPGIAKDLDIVSYKEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQH-DAVNFICDHPKIRAISFVGGDKAGRHIYERGSKNG-KRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGET--RNWIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNVPIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 TK+FIN ++ DS + + NPAT + I +V + K ++++AV + +AF+ W + +R M+KL +LI+RD +AA T + GK + A DV ++ E+ + G+ +P I D + EP+GV I P+NFP ++ W +L GNT++LK +E+ P + L EAGFPPG VN++ G A + HPK+ I+F G + G+ I + ++N KR+ +G K+ ++ DA ++ + A F GQ C A + ++V E ++ ++A AK+ KV D GP I + +I I+SG EGA++ G+ + G+ F+ PTI T V SM KEEIFGPV+ ++ ++ I NNN YG +IFT + TQ + G V VN V F G + S +G G+ G++ +T++K VT Sbjct: 37 TKIFINNEWHDSVSKKTFPTKNPATGQDICQVAEGGKEDIDKAVTAANKAFQLGSPWRKMDAADRGSLMYKLAQLIRRDADYLAALETLDSGKPVSIARAADVELTIKCYEYYAGWADKNHGKVIP-IRGDYIGFTRHEPVGVCGQIIPWNFPLLMQAWKLAPALSMGNTVVLKTAEQTPLTANYVASLAAEAGFPPGVVNIVPGMGPTAGAALVTHPKVDKIAFTGSTEVGQIISKHCNENNIKRLTLELGGKSPNIVFADADFDNAVKTSYFALFFNMGQCCCA-GSRIYVEEKIYDKFVEAMVAEAKS-KVVGNPFDNVDQGPQIDEEQMNKILGFIDSGKSEGAQMCTGGKQIGSKGF----FIEPTIFTKVEDSMRIAKEEIFGPVMQIMKFKDTNEVIARANNNEYGLAASIFTQDIDKSLHVTQSLRAGTVWVNC-YDVFDAAAPFGGYKSSGVGRE--LGEYGLSNYTEVKMVT 508
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 205.682 bits (522), Expect = 1.158e-56 Identity = 147/509 (28.88%), Postives = 252/509 (49.51%), Query Frame = 3 Query: 63 ASKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE--SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTL-LDAEGDVMRGLQVVEHCCSITNLQLGETMP-GIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHD-AVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRN--WIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 + K+L ++ N ++ IP ++FIN +FV+S++ + D NP+ VI RV +K +++ AV++ EAFE W + S +R + ++KL +L++ +++A + + G L + + ++ + + G T+P A+ +S+ KEP+GV ITP+N+P M+ W L GNT++LKP++ P A++ EL VEAGFP G +NV+ G A I +HP IR + F G G+ I +K N K+ +G K+ ++ D + + + F G+ C+A + +FV + ++ ++ K +K+ + + D GP + ++ + G KEGAK+V G+ GY F+ PTI T+V M +EE FGP++I + +D+ I N YG + +FTN + A + I G V +N V P F G + S G G++ +N + + KTVT Sbjct: 413 SQKKLHYDAVIINANKMTFPIPH-QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIA-AGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGY----FMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAP---FGGFKQSGFGKD--LGQEALNEYLKTKTVT 910
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 205.297 bits (521), Expect = 1.210e-56 Identity = 147/509 (28.88%), Postives = 252/509 (49.51%), Query Frame = 3 Query: 63 ASKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPATNKVISRVPKCTKPEMERAVESCAEAFE--SWSQRSVLNRQQYMFKLQELIKRDLKKIAANITSEQGKTL-LDAEGDVMRGLQVVEHCCSITNLQLGETMP-GIAKDLDIVSY--KEPLGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGATMMLMELCVEAGFPPGTVNVIHGQHD-AVNFICDHPKIRAISFVGGDKAGRHIYERGSK-NGKRVQANIGAKNHGVLMPDARKESTINQLVGAAFGAAGQRCMALSTAVFVGETRN--WIPDIIARAKNLKVSEGMQPGADLGPVISKHAKERIHSLIESGTKEGAKIVLDGRNLKVSGYEDGNFVGPTILTNVNPSMECYKEEIFGPVLICLEVDTLDDAIKLINNNPYGNGTAIFTNSGATARKFTQKIHVGQVGVNV--PIPVPLPMFSFTGSRGSFLGDTNFYGKQGVNFFTQLKTVT 1553 + K+L ++ N ++ IP ++FIN +FV+S++ + D NP+ VI RV +K +++ AV++ EAFE W + S +R + ++KL +L++ +++A + + G L + + ++ + + G T+P A+ +S+ KEP+GV ITP+N+P M+ W L GNT++LKP++ P A++ EL VEAGFP G +NV+ G A I +HP IR + F G G+ I +K N K+ +G K+ ++ D + + + F G+ C+A + +FV + ++ ++ K +K+ + + D GP + ++ + G KEGAK+V G+ GY F+ PTI T+V M +EE FGP++I + +D+ I N YG + +FTN + A + I G V +N V P F G + S G G++ +N + + KTVT Sbjct: 387 SQKKLHYDAVIINANKMTFPIPH-QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIA-AGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGY----FMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAP---FGGFKQSGFGKD--LGQEALNEYLKTKTVT 884 The following BLAST results are available for this feature:
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Methylmalonate-semialdehyde dehydrogenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032682 ID=SMED30032682|Name=Methylmalonate-semialdehyde dehydrogenase|organism=Schmidtea mediterranea sexual|type=transcript|length=1758bpback to top protein sequence of SMED30032682-orf-1 >SMED30032682-orf-1 ID=SMED30032682-orf-1|Name=SMED30032682-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=524bp MFYIASKRLTLRVHALSRNYLSTAIPKTKMFINGDFVDSQTTEWIDLPNPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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