VPS35 endosomal protein sorting factor-like

Overview


Name	VPS35 endosomal protein sorting factor-like
Smed ID	SMED30032674
Length (bp)	2962

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of VPS35 endosomal protein sorting factor-like (SMED30032674) t-SNE clustered cells

Violin plots show distribution of expression levels for VPS35 endosomal protein sorting factor-like (SMED30032674) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of VPS35 endosomal protein sorting factor-like (SMED30032674) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30032674

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30032674	h1SMcG0019769	Contig348	GPL15192	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30032674	h1SMcG0019769	dd_Smed_v4_5533_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30032674	h1SMcG0019769	dd_Smed_v4_5533_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30032674	h1SMcG0019769	dd_Smed_v4_5533_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Match: VPS35L (VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641])

HSP 1 Score: 498.049 bits (1281), Expect = 3.187e-160
Identity = 314/866 (36.26%), Postives = 490/866 (56.58%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS---------------DTS--KIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS   S+    DPLS               D+S  K D+  +S V S+ EPW++KR  IL+ YTT EKLSI + F+     E+ +    T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:   31 DYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLS---SVLDGTDPLSMFAATADPAALAAAMDSSRRKRDRDDNSVVGSDFEPWTNKRGEILARYTTTEKLSI-NLFM---GSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDSRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 857

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Match: VPS35L (VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641])

HSP 1 Score: 498.434 bits (1282), Expect = 2.428e-159
Identity = 314/866 (36.26%), Postives = 490/866 (56.58%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS---------------DTS--KIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS   S+    DPLS               D+S  K D+  +S V S+ EPW++KR  IL+ YTT EKLSI + F+     E+ +    T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:  120 DYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLS---SVLDGTDPLSMFAATADPAALAAAMDSSRRKRDRDDNSVVGSDFEPWTNKRGEILARYTTTEKLSI-NLFM---GSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDSRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 946

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Match: VPS35L (VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641])

HSP 1 Score: 498.434 bits (1282), Expect = 2.428e-159
Identity = 314/866 (36.26%), Postives = 490/866 (56.58%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS---------------DTS--KIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS   S+    DPLS               D+S  K D+  +S V S+ EPW++KR  IL+ YTT EKLSI + F+     E+ +    T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:  120 DYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLS---SVLDGTDPLSMFAATADPAALAAAMDSSRRKRDRDDNSVVGSDFEPWTNKRGEILARYTTTEKLSI-NLFM---GSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDSRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 946

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Match: VPS35L (VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641])

HSP 1 Score: 406.371 bits (1043), Expect = 4.600e-127
Identity = 250/739 (33.83%), Postives = 401/739 (54.26%), Query Frame = 3

Query:  408 TSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ                            G  VY+R+     D++S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:   29 TLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQ----------------------------GKLVYERIFSMCVDSRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKGN-HSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 707

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Match: VPS35L (VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641])

HSP 1 Score: 366.311 bits (939), Expect = 5.148e-113
Identity = 216/624 (34.62%), Postives = 349/624 (55.93%), Query Frame = 3

Query:  750 LQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:    9 LPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 606

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Celegans
Match: F26G1.1 (pep chromosome:WBcel235:II:4791620:4795643:1 gene:WBGene00017837.1 transcript:F26G1.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F26G1.1)

HSP 1 Score: 150.214 bits (378), Expect = 9.330e-37
Identity = 172/739 (23.27%), Postives = 328/739 (44.38%), Query Frame = 3

Query:  525 LQNALKISWRDGQRVKALQIIIQSTKLL-SDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQ--SPL------LVHSALNSIATSYIEKKPLYFAEMIHRLPES-SYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISC-------KCDFENLLSSQEF--TLYLAMFDKEPSLIEVRQIV---LDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEG-KNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSG--SASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTE---KSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSL-NSPVI 2654
            L+  L  +W    RV++ +I+I+S  LL S     + +P  ++L  D+VD+FG  +YDRL  KS + + N      L  NF   Q+P+  K+ A NWF K++ I ++  R YIE  ++ C KFFD+  +  +L RL  M     + L + +AR ++ R  + ++P  R       +D + + K + +  EL + K    D +   +   +  V WI+QC+  GA    +D +V      +  SPL      LV + +  + + Y+        ++I  L E    P   + K+      L+ A   E    +   VW  +  +S  + F++C  +W  ++ K     ++ K L  ++  +  D+Q  +  N   ++L  +I+        K D  ++++S  F   + L  +D + +    R+I+      F    ISD  +   +I+ C R L + Y     L  S+  +   +L+ + ++ I F+   N++  + L+ + R   G  ++ +  I+E + N    +     +R   SG   A F+R C+    +TIP++ D S  +++     Q+ L+   L Q E      I  L ++  +     A+V+ + +   ++L   P+            N+ M      L +   +  I++ +H       K +   ++YI +L  L    +   L    + D++  ++ G ++ L+ +      V+ K+ SL N P I
Sbjct:  178 LRENLITAWGREDRVESFKIVIESANLLQSIPPQSEEYPYYWLLAIDVVDTFGKLLYDRLLAKSNEAR-NKNGQTDLSANFTVEQVPKNVKDMAMNWFLKLSEIIDIPIRFYIECSMIACLKFFDAANLSINLERLAIMCSQFNDDLSSIFARVHITRYSMLIDPLNRTPHWRVLHDWMQAPKDVME--ELHRKKTSLADARKEAVS--IQGVSWIVQCVAHGA--HTVDDLVPLFAYCRKTSPLDEKTFILVSAVIEGLPSKYLSVHSEQVLDIIFALHEDFEEPLTRLGKRY-----LNMAPIEENRKFVKKSVWMRVADISNFQTFVDCCAAWTSYITKYYTLKEVTKILELVLVRLRIDDQTKKPEN--TALLINLIAAFLEHNANKSDCLDIVTSNSFIKIVDLIGYDIQSTSDCSRRILEIFSKTFTRHTISDISACQFIIEKC-RTLCKAY----RLEESEEVKAAEQLVCSSLSLIDFQAFTNLDQCIELIVRCREDMGLRQNSLIHIIETLFNFTQFI-----HRTQKSGKRKADFMRVCITNLSLTIPAVRDPSRRVKMTVQNIQMCLLANFLPQMEMSSVRVIEYLDEMSTNGPSVCATVSPLISQFLATLSFCPE----------GFNEEM----PSLSHFSKILAIVERNHEEWSKEYKGVPLAEIYINMLRYLCTCRKVDPL----RADSSQKLHFGDDDHLIRVDCNISDVITKLFSLANDPTI 874

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Fly
Match: CG8202 (gene:FBgn0037622 transcript:FBtr0081914)

HSP 1 Score: 373.244 bits (957), Expect = 1.297e-113
Identity = 275/893 (30.80%), Postives = 455/893 (50.95%), Query Frame = 3

Query:   39 RIYKFEKHC-NFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLG-QINDPLSD--------TSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKP--DEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDS--KQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFND---ILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASV--TEMAASLASSLLMFP-DINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVV----LKIRSLN 2642
            R Y+  K+C     T  HPL +  VT  +   +           S+++   DPLS  +    ++NDPLS         + + ++  +    N   WSS+R+ IL+ +TTNEKLS+ +SFL+     D     +   + + +K K R EQLD  D+  +R   +L  Q++  +  +L+  L  SW + QRVKAL+I IQ  K+L+DT  +QF+PS++VLITD++D FG  VY+RL+ K+  + + S    +     RE    E A++T QNWFYK+ASIREL+ R Y+E  +  CY+F  S  ++    L RL    RGI +PL+++YAR Y+ R+G+ L  + + Y++  F D   I   + R      L    + ++     YL+L+ PA D++L CL   +     D +    +   +  ++ S L+S  + +I    L F  +I+        K  + + LG+CVS S     E  +  L   ++ + KL++   +I C ++WA F+++     ++N+ L  +   M     Y +  +QLQ+IL +I+      E LL    F  YL +F KE   +EV + +L  F+  N  +   D V+    + + K + DS+N+LSV D RR + +LI   I+K+ F G ++E  L+   + R TF  +++V  ++V     LA   R         S S  FV+AC+A+ +ITIPSIE +   + LY    Q+AL + CLGQA++C + A+ L+++      +PAA+V       SL   L+ +  +I + L+    +  Q +LY L+ L+  +       +   P   SII    Y+  L +L   S   + Y      +ND +YG    FL  ++++  +VV    L+++SL 
Sbjct:   11 RCYEVRKNCLTGQATLEHPLKQRTVTVVDSNPL-----------SRALEGTDPLSQFARQDDELNDPLSQMVSEFDLKSKRRERDRTEPEDNTLQWSSRRLGILNRFTTNEKLSLSTSFLVSSGSLDGGNESIKAQTVVADKTKFRLEQLDHFDDGSMRHMMDLTQQEYIQRFEQLKQELIQSWHNDQRVKALKIAIQCAKMLADTTVLQFYPSQYVLITDILDVFGKLVYERLRAKASGDPAASAATLE-----RER---EAARDTCQNWFYKIASIRELLPRFYLELSIFKCYEFLSSSREEYERILQRLTHQLRGIADPLVSSYARCYLVRMGVTLTSS-KTYIRENFADLFLIYPQIFRFVARFNLHPEIVTASS----YLQLYAPAFDYMLLCLVHKSELHTQDILNECKQLKNNGAILMSVLSSFNSEFIATNALEFIALINASETPGISKSQLLRSLGSCVS-SCPPLQEQRVTFLKAAFETINKLTDPNEYINCVETWAVFVSQYFTIHEVNRLLGELNTRMCLGKAYEKHYSQLQNILTRIMQNYRSIELLLIQPNFLPYLDLFQKESVRVEVCKNILS-FYKQNSDEYTCDAVVTNALMYLGKILNDSVNALSVDDERRQIAQLINVFIHKVHF-GNDLEQQLSFYVEARGTFSNLDAVYVTLVHAACKLATRNR---------SKSTGFVKACIAYCFITIPSIEAVQQQMNLYLLCGQLALQHLCLGQADACFEAALQLVNE------LPAATVDFDGKPRSLEPFLVSYMCNILATLIVVPDSPEQGVLYFLRLLLEVVGRHKFKVDSSAP---SII----YLHSLDMLYVQSLERFPYHIKGVVSNDDLYGHDPKFLQEVNNMCAQVVDAILLQLKSLG 854

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Zebrafish
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 498.049 bits (1281), Expect = 1.964e-160
Identity = 320/887 (36.08%), Postives = 502/887 (56.60%), Query Frame = 3

Query:   78 TDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS------DTSKIDQVFSS-------------TVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNV-RSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISD----VFGKVVLKIRSLN 2642
            +D HPL    VT     +   K +  + +SS S +  DPLS   S+    DPLS      +T  +    S+                + EPWSSKR  ILS +TT EKLSI + F+     +  +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VYDR+     D       PH L ++F    + + AKET  NWF+K+ASIREL+ RLY+EA LL C +F     I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++   +  ++L +     +IP YL L+ PA++WILQC+   A +  +  ++   +    + LL++S + +    ++  +   F  MI    E+ +PK+ ++  LG  +S +     E  L +L+  WK +TK+   R +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   DF  L S ++F  +L MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + R+TF  +E VI  ++  VN LAM   R ++ N  H+  +A+FVRAC A+S+ITIPS+ +I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R+I   S+     S  S LL F  IN+ L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  I+     + G+V+  ++SL 
Sbjct:   30 SDYHPLKAITVTDSKSRRGGRKGSTSSSSSSSSSVAPDPLS---SMLDGTDPLSLFAAASETPTLPHSVSAGELGRKRKEKEEEVGLDFEPWSSKRGEILSRFTTTEKLSI-NLFM---GSDTSKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVNRIEELNQSLKEAWGSDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGGLVYDRIWSMCAD-------PHPLPESFSADDVNDTAKETCLNWFFKIASIRELVPRLYVEAALLKCNRFLTKCGIQETLQRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHGDSVQNQLVLQRV--EIPVYLTLYSPAINWILQCVAYRAPEVLLTEMMDRCKKLGNNALLLNSVMWAFRAEFVATRATDFIGMIKDCDEAGFPKHLLFASLGRSLSCADPPESE-RLSILNEAWKVITKVRSPRDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVIKKILTYFHDFSMLFSMEKFLPFLDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHICKTMHDSVNALTLDDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLEPVIIHLIHTVNQLAMETGRVMKGN--HSRKTAAFVRACAAYSFITIPSLTNIFSRLNLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRSI---SIEGKQRSSESFLLDF--INNFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQESYLYTIPKVDSNETLYGGDPKFIAEINKLCETLIGQVLDHLKSLG 879

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:Xenbase;Acc:XB-GENE-950061])

HSP 1 Score: 510.375 bits (1313), Expect = 5.429e-165
Identity = 317/892 (35.54%), Postives = 500/892 (56.05%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLII-DPLSANSSLGQINDPLSDTSKIDQVFSSTV--------------SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKR 2663
            D HPL    VT+    KV  K +  + +SS S   + DPLS   S+    DPLS  +   +  +S V              S+ EPWSSKR  IL+ YTT EKLSI + F+     +  +  N  S++ EKV+TR E+LD ++E   +E  NL  Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     D++S+      L +NF    + + AKET  NWF+K+ASIREL+ R Y+EA +L C KF     I +SL RL  M RGIG+PL+A YAR+Y+ R+G+ + PN ++ L   F D L + K +      ++L + +   +IP YL L+ PA+DW+L+C+   A ++ +  ++    +   + LL++S +++    +I  + + F  MI    E+ +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I C++ W E+  ++    ++N  LA I+K MT D  + +   QLQS++ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN+LAM  + +     H+  +ASFVRAC+AFS+ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+      I ID  + ++   + E   +  S+LL+ PD        +P Q   +L+L++GL+N I        D+   + S  K  +Y  +L +LAA SQ  YL    K D+ND +YGG   FL  I+     + G+++  +++L      KR
Sbjct:   34 DYHPLKPIMVTESKTKKVGRKESTSSSSSSCSSNSVADPLS---SVLDGTDPLSLFAATAEPVASNVDGKRKKNENEEYVGSDFEPWSSKRGEILARYTTTEKLSI-NLFM---GSDRGKTTNAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYISRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERISSMCLDSRSS------LPENFSPETVNDTAKETCLNWFFKIASIRELVPRFYVEAAILKCNKFLSKTGISESLPRLTTMIRGIGDPLVAVYARAYLCRVGMEVAPNVKESLNRNFFDFLLTFKLIHSDTVQNQLAVQAV--EIPVYLTLYSPAIDWMLRCIAYRAPETLLTEMMERCKKQGNNALLLNSVMSAFRADFIATRSMDFIGMIKECDEAGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLRNPQDYINCSEVWVEYTCRHFTKREVNTILADIIKHMTPDRAFEDAYQQLQSVITKVITHFQDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIRHQ-QEVTKDPVILNALLHVCKTMHDSVNALTLEDEKRTLANLINGFIRMVSF-GRDFEQQLSFYVETRSMFCNLEPVLIQLIHSVNHLAMETKKVMKG-NHSRKTASFVRACVAFSFITIPSLTSIFTRLNLYLLSGQVALANQCLSQADAFFKAAVSLVPDVPKTISIDGKMRSSEPFLLEFLGNFFSTLLVVPD--------HPEQG--VLFLVRGLLNVI-------EDYTWEDNSDDKVRIYTSVLHLLAALSQESYLLHVDKVDSNDNLYGGDTKFLAEINRLCDTLIGQILEHLKTLGKEKTLKR 886

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:Xenbase;Acc:XB-GENE-950061])

HSP 1 Score: 492.656 bits (1267), Expect = 2.852e-158
Identity = 317/892 (35.54%), Postives = 496/892 (55.61%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLII-DPLSANSSLGQINDPLSDTSKIDQVFSSTV--------------SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKR 2663
            D HPL    VT+    KV  K +  + +SS S   + DPLS   S+    DPLS  +   +  +S V              S+ EPWSSKR  IL+ YTT EKLSI + F+     +  +  N  S++ EKV+TR E+LD ++E   +E  NL  Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     D++S+      L +NF    + + AKET  NWF+K+ASIREL+ R Y+EA +L C KF     I +SL RL  M RGIG+PL+A YAR+Y+ R+G+ + PN ++ L   F D L + K +      ++L + +   +IP YL L+ PA+DW+L+C+   A ++ +  ++    +   + LL++S +++    +I  + + F  MI    E+ +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TK+   RYF  C  +    +   L   ++N  LA I+K MT D  + +   QLQS++ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN+LAM  + +     H+  +ASFVRAC+AFS+ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+      I ID  + ++   + E   +  S+LL+ PD        +P Q   +L+L++GL+N I        D+   + S  K  +Y  +L +LAA SQ  YL    K D+ND +YGG   FL  I+     + G+++  +++L      KR
Sbjct:   30 DYHPLKPIMVTESKTKKVGRKESTSSSSSSCSSNSVADPLS---SVLDGTDPLSLFAATAEPVASNVDGKRKKNENEEYVGSDFEPWSSKRGEILARYTTTEKLSI-NLFM---GSDRGKTTNAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYISRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERISSMCLDSRSS------LPENFSPETVNDTAKETCLNWFFKIASIRELVPRFYVEAAILKCNKFLSKTGISESLPRLTTMIRGIGDPLVAVYARAYLCRVGMEVAPNVKESLNRNFFDFLLTFKLIHSDTVQNQLAVQAV--EIPVYLTLYSPAIDWMLRCIAYRAPETLLTEMMERCKKQGNNALLLNSVMSAFRADFIATRSMDFIGMIKECDEAGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKI---RYF--CCITVEPLILCILQKREVNTILADIIKHMTPDRAFEDAYQQLQSVITKVITHFQDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIRHQ-QEVTKDPVILNALLHVCKTMHDSVNALTLEDEKRTLANLINGFIRMVSF-GRDFEQQLSFYVETRSMFCNLEPVLIQLIHSVNHLAMETKKVMKG-NHSRKTASFVRACVAFSFITIPSLTSIFTRLNLYLLSGQVALANQCLSQADAFFKAAVSLVPDVPKTISIDGKMRSSEPFLLEFLGNFFSTLLVVPD--------HPEQG--VLFLVRGLLNVI-------EDYTWEDNSDDKVRIYTSVLHLLAALSQESYLLHVDKVDSNDNLYGGDTKFLAEINRLCDTLIGQILEHLKTLGKEKTLKR 877

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:Xenbase;Acc:XB-GENE-950061])

HSP 1 Score: 488.034 bits (1255), Expect = 7.952e-157
Identity = 314/892 (35.20%), Postives = 491/892 (55.04%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLII-DPLSANSSLGQINDPLSDTSKIDQVFSSTV--------------SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKR 2663
            D HPL    VT+    KV  K +  + +SS S   + DPLS   S+    DPLS  +   +  +S V              S+ EPWSSKR  IL+ YTT EKLSI + F+     +  +  N  S++ EKV+TR E+LD ++E   +E  NL  Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     D++S+      L +NF    + + AKET  NWF+K+ASIREL+ R Y+EA +L C KF     I +SL RL  M RGIG+PL+A YAR+Y+ R+G+ + PN ++ L   F D L + K +      ++L + +   +IP YL L+ PA+DW+L+C+   A ++ +  ++    +   + LL++S +++    +I  + + F  MI    E+ +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL                  +N    ++N  LA I+K MT D  + +   QLQS++ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN+LAM  + +     H+  +ASFVRAC+AFS+ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+      I ID  + ++   + E   +  S+LL+ PD        +P Q   +L+L++GL+N I        D+   + S  K  +Y  +L +LAA SQ  YL    K D+ND +YGG   FL  I+     + G+++  +++L      KR
Sbjct:   20 DYHPLKPIMVTESKTKKVGRKESTSSSSSSCSSNSVADPLS---SVLDGTDPLSLFAATAEPVASNVDGKRKKNENEEYVGSDFEPWSSKRGEILARYTTTEKLSI-NLFM---GSDRGKTTNAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYISRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERISSMCLDSRSS------LPENFSPETVNDTAKETCLNWFFKIASIRELVPRFYVEAAILKCNKFLSKTGISESLPRLTTMIRGIGDPLVAVYARAYLCRVGMEVAPNVKESLNRNFFDFLLTFKLIHSDTVQNQLAVQAV--EIPVYLTLYSPAIDWMLRCIAYRAPETLLTEMMERCKKQGNNALLLNSVMSAFRADFIATRSMDFIGMIKECDEAGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKL------------------RNPQKREVNTILADIIKHMTPDRAFEDAYQQLQSVITKVITHFQDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIRHQ-QEVTKDPVILNALLHVCKTMHDSVNALTLEDEKRTLANLINGFIRMVSF-GRDFEQQLSFYVETRSMFCNLEPVLIQLIHSVNHLAMETKKVMKG-NHSRKTASFVRACVAFSFITIPSLTSIFTRLNLYLLSGQVALANQCLSQADAFFKAAVSLVPDVPKTISIDGKMRSSEPFLLEFLGNFFSTLLVVPD--------HPEQG--VLFLVRGLLNVI-------EDYTWEDNSDDKVRIYTSVLHLLAALSQESYLLHVDKVDSNDNLYGGDTKFLAEINRLCDTLIGQILEHLKTLGKEKTLKR 854

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:Xenbase;Acc:XB-GENE-950061])

HSP 1 Score: 484.182 bits (1245), Expect = 1.358e-155
Identity = 310/884 (35.07%), Postives = 487/884 (55.09%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLII-DPLSANSSLGQINDPLSDTSKIDQVFSS-------------TVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLN 2642
            D HPL    VT+    KV  K +  + +SS S   + DPLS   S+    DPLS  +   +  +S               S+ EPWSSKR  IL+ YTT EKLSI + F+     +  +  N  S++ EKV+TR E+LD ++E   +E  NL  Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     D++S+      L +NF    + + AKET  NWF+K+ASIREL+ R Y+EA +L C KF     I +SL RL  M RGIG+PL+A YAR+Y+ R+G+ + PN ++ L   F D L + K +      ++L + +   +IP YL L+ PA+DW+L+C+   A ++ +  ++    +   + LL++S +++    +I  + + F  MI    E+ +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL                  +N    ++N  LA I+K MT D  + +   QLQS++ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN+LAM  + +     H+  +ASFVRAC+AFS+ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+      I ID  + ++   + E   +  S+LL+ PD          +  Q +L+L++GL+N I        D+   + S  K  +Y  +L +LAA SQ  YL    K D+ND +YGG   FL  I+     + G+++  +++L 
Sbjct:   32 DYHPLKPIMVTESKTKKVGRKESTSSSSSSCSSNSVADPLS---SVLDGTDPLSLFAATAEPVASNDGKRKKNENEEYVGSDFEPWSSKRGEILARYTTTEKLSI-NLFM---GSDRGKTTNAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYISRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERISSMCLDSRSS------LPENFSPETVNDTAKETCLNWFFKIASIRELVPRFYVEAAILKCNKFLSKTGISESLPRLTTMIRGIGDPLVAVYARAYLCRVGMEVAPNVKESLNRNFFDFLLTFKLIHSDTVQNQLAVQAV--EIPVYLTLYSPAIDWMLRCIAYRAPETLLTEMMERCKKQGNNALLLNSVMSAFRADFIATRSMDFIGMIKECDEAGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKL------------------RNPQKREVNTILADIIKHMTPDRAFEDAYQQLQSVITKVITHFQDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIRHQ-QEVTKDPVILNALLHVCKTMHDSVNALTLEDEKRTLANLINGFIRMVSF-GRDFEQQLSFYVETRSMFCNLEPVLIQLIHSVNHLAMETKKVMKG-NHSRKTASFVRACVAFSFITIPSLTSIFTRLNLYLLSGQVALANQCLSQADAFFKAAVSLVPDVPKTISIDGKMRSSEPFLLEFLGNFFSTLLVVPD----------HPEQGVLFLVRGLLNVI-------EDYTWEDNSDDKVRIYTSVLHLLAALSQESYLLHVDKVDSNDNLYGGDTKFLAEINRLCDTLIGQILEHLKTLG 858

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:Xenbase;Acc:XB-GENE-950061])

HSP 1 Score: 485.337 bits (1248), Expect = 1.425e-155
Identity = 313/891 (35.13%), Postives = 490/891 (54.99%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLII-DPLSANSSLGQINDPLSDTSKIDQVFSS-------------TVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKR 2663
            D HPL    VT+    KV  K +  + +SS S   + DPLS   S+    DPLS  +   +  +S               S+ EPWSSKR  IL+ YTT EKLSI + F+     +  +  N  S++ EKV+TR E+LD ++E   +E  NL  Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     D++S+      L +NF    + + AKET  NWF+K+ASIREL+ R Y+EA +L C KF     I +SL RL  M RGIG+PL+A YAR+Y+ R+G+ + PN ++ L   F D L + K +      ++L + +   +IP YL L+ PA+DW+L+C+   A ++ +  ++    +   + LL++S +++    +I  + + F  MI    E+ +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL                  +N    ++N  LA I+K MT D  + +   QLQS++ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN+LAM  + +     H+  +ASFVRAC+AFS+ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+      I ID  + ++   + E   +  S+LL+ PD        +P Q   +L+L++GL+N I        D+   + S  K  +Y  +L +LAA SQ  YL    K D+ND +YGG   FL  I+     + G+++  +++L      KR
Sbjct:   44 DYHPLKPIMVTESKTKKVGRKESTSSSSSSCSSNSVADPLS---SVLDGTDPLSLFAATAEPVASNDGKRKKNENEEYVGSDFEPWSSKRGEILARYTTTEKLSI-NLFM---GSDRGKTTNAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYISRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERISSMCLDSRSS------LPENFSPETVNDTAKETCLNWFFKIASIRELVPRFYVEAAILKCNKFLSKTGISESLPRLTTMIRGIGDPLVAVYARAYLCRVGMEVAPNVKESLNRNFFDFLLTFKLIHSDTVQNQLAVQAV--EIPVYLTLYSPAIDWMLRCIAYRAPETLLTEMMERCKKQGNNALLLNSVMSAFRADFIATRSMDFIGMIKECDEAGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKL------------------RNPQKREVNTILADIIKHMTPDRAFEDAYQQLQSVITKVITHFQDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIRHQ-QEVTKDPVILNALLHVCKTMHDSVNALTLEDEKRTLANLINGFIRMVSF-GRDFEQQLSFYVETRSMFCNLEPVLIQLIHSVNHLAMETKKVMKG-NHSRKTASFVRACVAFSFITIPSLTSIFTRLNLYLLSGQVALANQCLSQADAFFKAAVSLVPDVPKTISIDGKMRSSEPFLLEFLGNFFSTLLVVPD--------HPEQG--VLFLVRGLLNVI-------EDYTWEDNSDDKVRIYTSVLHLLAALSQESYLLHVDKVDSNDNLYGGDTKFLAEINRLCDTLIGQILEHLKTLGKEKTLKR 877

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Match: Vps35l (VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767])

HSP 1 Score: 498.049 bits (1281), Expect = 4.870e-160
Identity = 318/914 (34.79%), Postives = 505/914 (55.25%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDP-----LSDTS--KIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI-RSLNSPVIDKRLK-------DVLSIVLKSEDILNNSI 2720
            D HPL    VT+    KV  K +  + +SS S  +IDPLS+        S     +DP     ++D+S  K D+  +S V  + EPW++KR+ IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+GI + P+ ++ L   F D L + K++      ++L     +  + YL L+ PA+ WI QC+   A ++ +  ++   +    + LL++S +++    ++  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AI L+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL   S +   V+ +I   L +   D+ LK          + +L   D+ NN +
Sbjct:   59 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVIDPLSSVLDGTDPLSMFAATSDPAATGTVTDSSRKKRDKDENSFVGPDFEPWANKRVEILARYTTTEKLSI-NLFM---GSEKGRGGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERISSMCVDSRS------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGIEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVAQGVE-LLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFVATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIQKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIKHQ-QEPTKDPVILNALLHICKTMHDSVNALTLEDEKRTLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAIGLVPEVPKTISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSKFLAENSKLCEAVMAQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKL 937

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Match: Vps35l (VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767])

HSP 1 Score: 471.855 bits (1213), Expect = 1.005e-150
Identity = 311/914 (34.03%), Postives = 492/914 (53.83%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDP-----LSDTS--KIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI-RSLNSPVIDKRLK-------DVLSIVLKSEDILNNSI 2720
            D HPL    VT+    KV  K +  + +SS S  +IDPLS+        S     +DP     ++D+S  K D+  +S V  + EPW++KR+ IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+GI + P+ ++ L   F D L + K++      ++L     +  + YL L+ PA+ WI QC+   A ++ +  ++   +    + LL++S +++    ++  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F                            +N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AI L+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL   S +   V+ +I   L +   D+ LK          + +L   D+ NN +
Sbjct:   35 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVIDPLSSVLDGTDPLSMFAATSDPAATGTVTDSSRKKRDKDENSFVGPDFEPWANKRVEILARYTTTEKLSI-NLFM---GSEKGRGGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERISSMCVDSRS------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGIEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVAQGVE-LLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFVATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIQKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAF----------------------------INALTLEDEKRTLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAIGLVPEVPKTISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSKFLAENSKLCEAVMAQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKL 886

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Match: Vps35l (VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767])

HSP 1 Score: 367.851 bits (943), Expect = 1.273e-113
Identity = 228/704 (32.39%), Postives = 375/704 (53.27%), Query Frame = 3

Query:  663 LVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI-RSLNSPVIDKRLK-------DVLSIVLKSEDILNNSI 2720
            L+   G  VY+R+     D++S       L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+GI + P+ ++ L   F D L + K++      ++L     +  + YL L+ PA+ WI QC+   A ++ +  ++   +    + LL++S +++    ++  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AI L+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL   S +   V+ +I   L +   D+ LK          + +L   D+ NN +
Sbjct:    2 LLAGHGKLVYERISSMCVDSRS------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGIEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVAQGVE-LLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFVATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIQKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIKHQ-QEPTKDPVILNALLHICKTMHDSVNALTLEDEKRTLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAIGLVPEVPKTISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSKFLAENSKLCEAVMAQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKL 674

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Match: Vps35l (VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767])

HSP 1 Score: 228.794 bits (582), Expect = 3.365e-62
Identity = 139/321 (43.30%), Postives = 197/321 (61.37%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDP-----LSDTS--KIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVAR 995
            D HPL    VT+    KV  K +  + +SS S  +IDPLS+        S     +DP     ++D+S  K D+  +S V  + EPW++KR+ IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R
Sbjct:   35 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVIDPLSSVLDGTDPLSMFAATSDPAATGTVTDSSRKKRDKDENSFVGPDFEPWANKRVEILARYTTTEKLSI-NLFM---GSEKGRGGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERISSMCVDSRS------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCR 345

HSP 2 Score: 216.853 bits (551), Expect = 3.998e-58
Identity = 149/508 (29.33%), Postives = 252/508 (49.61%), Query Frame = 3

Query: 1248 LLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI-RSLNSPVIDKRLK-------DVLSIVLKSEDILNNSI 2720
            LL++S +++    ++  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++                            AC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AI L+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL   S +   V+ +I   L +   D+ LK          + +L   D+ NN +
Sbjct:  363 LLLNSVMSAFRAEFVATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIQKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIKHQ-QEPTKDPVILNALLHICKTMHDSVNALTLEDEKRTLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIH---------------------------ACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAIGLVPEVPKTISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSKFLAENSKLCEAVMAQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKL 820

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Match: Vps35l (VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767])

HSP 1 Score: 136.732 bits (343), Expect = 1.564e-35
Identity = 92/216 (42.59%), Postives = 133/216 (61.57%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDP-----LSDTS--KIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEV-RETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFG 680
            D HPL    VT+    KV  K +  + +SS S  +IDPLS+        S     +DP     ++D+S  K D+  +S V  + EPW++KR+ IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG
Sbjct:   30 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVIDPLSSVLDGTDPLSMFAATSDPAATGTVTDSSRKKRDKDENSFVGPDFEPWANKRVEILARYTTTEKLSI-NLFM---GSEKGRGGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFG 241

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BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Match: sp|Q8BWQ6|VP35L_MOUSE (VPS35 endosomal protein sorting factor-like OS=Mus musculus OX=10090 GN=Vps35l PE=1 SV=2)

HSP 1 Score: 498.049 bits (1281), Expect = 1.406e-159
Identity = 318/914 (34.79%), Postives = 505/914 (55.25%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDP-----LSDTS--KIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI-RSLNSPVIDKRLK-------DVLSIVLKSEDILNNSI 2720
            D HPL    VT+    KV  K +  + +SS S  +IDPLS+        S     +DP     ++D+S  K D+  +S V  + EPW++KR+ IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+GI + P+ ++ L   F D L + K++      ++L     +  + YL L+ PA+ WI QC+   A ++ +  ++   +    + LL++S +++    ++  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AI L+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL   S +   V+ +I   L +   D+ LK          + +L   D+ NN +
Sbjct:   31 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVIDPLSSVLDGTDPLSMFAATSDPAATGTVTDSSRKKRDKDENSFVGPDFEPWANKRVEILARYTTTEKLSI-NLFM---GSEKGRGGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERISSMCVDSRS------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGIEVAPHLKESLNKNFFDFLLTFKQIHGDTVQNQLVAQGVE-LLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFVATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIQKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAFIKHQ-QEPTKDPVILNALLHICKTMHDSVNALTLEDEKRTLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAIGLVPEVPKTISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSKFLAENSKLCEAVMAQILEHLKTLAKDEALKRQSLLGLSFFNSILAHGDLRNNKL 909

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Match: sp|A4VCH4|VP35L_DANRE (VPS35 endosomal protein sorting factor-like OS=Danio rerio OX=7955 GN=vps35l PE=2 SV=1)

HSP 1 Score: 498.049 bits (1281), Expect = 1.483e-159
Identity = 320/887 (36.08%), Postives = 502/887 (56.60%), Query Frame = 3

Query:   78 TDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS------DTSKIDQVFSS-------------TVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNV-RSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISD----VFGKVVLKIRSLN 2642
            +D HPL    VT     +   K +  + +SS S +  DPLS   S+    DPLS      +T  +    S+                + EPWSSKR  ILS +TT EKLSI + F+     +  +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VYDR+     D       PH L ++F    + + AKET  NWF+K+ASIREL+ RLY+EA LL C +F     I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++   +  ++L +     +IP YL L+ PA++WILQC+   A +  +  ++   +    + LL++S + +    ++  +   F  MI    E+ +PK+ ++  LG  +S +     E  L +L+  WK +TK+   R +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   DF  L S ++F  +L MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L++ D +R +  LI   I  + F G++ E  L+   + R+TF  +E VI  ++  VN LAM   R ++ N  H+  +A+FVRAC A+S+ITIPS+ +I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R+I   S+     S  S LL F  IN+ L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  I+     + G+V+  ++SL 
Sbjct:   30 SDYHPLKAITVTDSKSRRGGRKGSTSSSSSSSSSVAPDPLS---SMLDGTDPLSLFAAASETPTLPHSVSAGELGRKRKEKEEEVGLDFEPWSSKRGEILSRFTTTEKLSI-NLFM---GSDTSKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVNRIEELNQSLKEAWGSDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGGLVYDRIWSMCAD-------PHPLPESFSADDVNDTAKETCLNWFFKIASIRELVPRLYVEAALLKCNRFLTKCGIQETLQRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHGDSVQNQLVLQRV--EIPVYLTLYSPAINWILQCVAYRAPEVLLTEMMDRCKKLGNNALLLNSVMWAFRAEFVATRATDFIGMIKDCDEAGFPKHLLFASLGRSLSCADPPESE-RLSILNEAWKVITKVRSPRDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVIKKILTYFHDFSMLFSMEKFLPFLDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHICKTMHDSVNALTLDDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLEPVIIHLIHTVNQLAMETGRVMKGN--HSRKTAAFVRACAAYSFITIPSLTNIFSRLNLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRSI---SIEGKQRSSESFLLDF--INNFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQESYLYTIPKVDSNETLYGGDPKFIAEINKLCETLIGQVLDHLKSLG 879

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Match: sp|Q7Z3J2|VP35L_HUMAN (VPS35 endosomal protein sorting factor-like OS=Homo sapiens OX=9606 GN=VPS35L PE=1 SV=2)

HSP 1 Score: 498.049 bits (1281), Expect = 1.531e-159
Identity = 314/866 (36.26%), Postives = 490/866 (56.58%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS---------------DTS--KIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS   S+    DPLS               D+S  K D+  +S V S+ EPW++KR  IL+ YTT EKLSI + F+     E+ +    T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  L S ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:   31 DYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLS---SVLDGTDPLSMFAATADPAALAAAMDSSRRKRDRDDNSVVGSDFEPWTNKRGEILARYTTTEKLSI-NLFM---GSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDSRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLAGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 857

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BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Match: sp|Q5R8N4|VP35L_PONAB (VPS35 endosomal protein sorting factor-like OS=Pongo abelii OX=9601 GN=VPS35L PE=2 SV=1)

HSP 1 Score: 496.893 bits (1278), Expect = 4.144e-159
Identity = 313/866 (36.14%), Postives = 487/866 (56.24%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS-----------------DTSKIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PAAS-VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS   S+    DPLS                    K D+  +S V S+ EPW++KR  IL+ YTT EKLSI + F+     E+ +    T ++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KL SDT+ +QF+PSKFVLITD++D+FG  VY+R+     DN+S       L D+F      + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L +     ++P YL L+ PA+DWI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQ I+ K+I+   DF  LLS ++F  +L MF KE   +EV + ++D F      +   DPV++   + + K M+DS+N+L++ D +R+++ LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  + P+ S + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:   31 DYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLS---SVLDGTDPLSMFAATADPAALAAATDSSRKKRDRDDNSIVGSDFEPWANKRGEILARYTTTEKLSI-NLFM---GSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLPSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRS------VLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--ELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLLSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQ-QEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFL 857

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Match: sp|Q5XI83|VP35L_RAT (VPS35 endosomal protein sorting factor-like OS=Rattus norvegicus OX=10116 GN=Vps35l PE=2 SV=1)

HSP 1 Score: 469.159 bits (1206), Expect = 9.072e-149
Identity = 299/860 (34.77%), Postives = 469/860 (54.53%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDPL-------SDTSKIDQVFSSTVS-NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHE-PALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D HPL    VT+    KV  K +  + +SS S  ++DPLS+        S     +DP        S   K D+  +S V  + EPW++KR  IL+ YTT EKLSI + F+     E+ R     S++ EKV+TR E+LD  +E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D++        L D+F    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL++ YAR+Y+ R+G+ + P+ ++ L   F D L + K++      ++L     +  + YL L+ PA+ WI QC+   A ++ +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG  V+L+ A   E   LQ+L+  WK +TKL   + +I CA+ W E+  ++    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F                            +N+L++ D +R++  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+A+ +ITIPS+  I   + LY  + QVAL N CL QA++  K AISL+ +    I ID  +  +   + E   +  S+LL+ PD        +P     +L+L++ L+N I        D+   + S  K  +Y  +L +L+A SQ  YLY   K D+ND++YGG   FL
Sbjct:   31 DYHPLKPITVTESKTKKVSRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAATSDPAATVTVTESSRKKRDKDDNSFVGPDFEPWANKRGEILARYTTTEKLSI-NLFM---GSEKGRAGAAASAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGKLVYERIYSMCVDSRG------ALPDHFSPENVNDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKESLTRNFFDFLLTFKQIHGDTVQNQLVAQGVE-LLSYLPLYSPAMGWIFQCVSYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLG--VNLALADPPENDRLQILNEAWKVITKLKSPQDYINCAEVWVEYTCRHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQSIIKKVIAHFHDFSVLFSVEKFLPFLDMFQKESVRVEVCKCIMEAF----------------------------INALTLEDEKRMLAHLINGFIKMVSF-GRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKG-NHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKSISIDGKLRPSEPFLLEFLCNFFSTLLIVPD--------HPEHG--VLFLVRELLNVI-------QDYTWEDSSDDKIRIYTSVLHLLSAMSQDTYLYHIDKVDSNDSLYGGDSRFL 830

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Match: A0A1S3I576 (UPF0505 protein C16orf62 homolog OS=Lingula unguis OX=7574 GN=LOC106161104 PE=4 SV=1)

HSP 1 Score: 546.199 bits (1406), Expect = 1.822e-175
Identity = 307/828 (37.08%), Postives = 497/828 (60.02%), Query Frame = 3

Query:  189 DPLSANSSLGQIND---PLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIEST-QSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKI----EIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRS 2636
            DPLS  S+     +   P  + + +D+ F       EPWS K++SIL+ +TT+EKL+I +SFL     + + ++   S++ +KVK R EQLD  +E  V+E  +L+ Q++ ++I+EL  AL  +W   QRVKAL+I IQ +KLLSDT  +QF+PSKFVLITD++D+FG  V++R++ KS      S +P QL +NF   Q+P+ AKET +NWF+K+ASIRELI R Y+E  +L CY F D+ +   +L RL  M RG+G+PL+  YAR Y++R+GIA+ PN RD+L   FND L    +L   +  + L +     ++P YL L+ PA+DWILQC+   A+++ + +I+   +    S LL++S +++    YI  + + F E I    E+ +PK+ +Y  LG C+ L+ +   +  L +L+ VWK + KL     +I CA+ W E++AK+ +  ++N  L  ++K MT D  + ++  QLQSI+ K++S   DF  L S  +F  ++ +F KE   +EV + +++ F     +++ SDPV+I   + + K M+DS+N+L++ D  R +  LI   + KI F G++ E  L+   + R+ F  +++V+  +VE VN LA+  R +   + H+  +ASFVRAC A+ +ITIPS++ +   ++LY  + QVAL+N CL Q ++ +K AISL++++    ++D  + +    +T    SL S+LL  PD        NP+Q   +LYLL+GL+N ++  P   N       S  K  +Y+ +L +L A SQ  Y+Y   + DAND++YG    FL  ++ +   V+ ++ S
Sbjct:   81 DPLSRMSTQTTTKEKSMPKDENNGLDETF-------EPWSVKKLSILTKHTTSEKLTITTSFLSAHEKDRV-VIKAQSTVTDKVKNRLEQLDDFEEGSVQEMLDLSQQEYVNRIDELNQALIDAWDQDQRVKALKIAIQCSKLLSDTNVIQFYPSKFVLITDILDTFGKLVFERIRSKSNYIPVGSSMPIQLPENFTPEQVPDSAKETCRNWFFKIASIRELIPRFYVETAILKCYSFLDTSEYSAALCRLADMTRGMGDPLVGIYARCYLSRVGIAVAPNIRDHLMPCFNDFLACYSQLQSDHVQNTLAMQKV--EMPRYLTLYCPALDWILQCIAHRASENTLQTILEKCKKLFNSALLLNSIMSAFKPEYIAFRAVQFTEQIRECEETGFPKHMLYCSLGGCLVLA-SPPEDQRLAVLNEVWKVVMKLKNPLDYITCAEVWIEYVAKHFSKREVNTILNDVIKHMTPDRAFEDYYPQLQSIVTKVLSHIHDFTLLFSLDKFLPFIDLFQKEIVKVEVCKSIMEAFVKYQ-AEATSDPVIINALMFICKTMHDSVNALTLDDEVRAIGGLICGFVRKISF-GRDFEQQLSFYVEARANFSNLDAVLVELVECVNTLAVETRDVVKGK-HSRKTASFVRACAAYCFITIPSLQSVLARLKLYLVSGQVALLNQCLSQGDAFLKAAISLIAEVPKTLDVDGKVRSTEPLMTSYICSLLSTLLAVPD--------NPDQG--VLYLLRGLLNVLSDFPWDVN-------SSAKAVVYVNVLSLLCAVSQEDYVYHIDRVDANDSMYGSDPKFLGEVTKISATVLEEVFS 877

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Match: A0A0B7AIC1 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF116826 PE=4 SV=1)

HSP 1 Score: 537.339 bits (1383), Expect = 6.118e-172
Identity = 322/926 (34.77%), Postives = 528/926 (57.02%), Query Frame = 3

Query:   84 SHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVL--IIDPLSANSSLGQIN----DPLSDTSKIDQVFSSTVSN-------------------IEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRI----LNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAAS-------VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL----LVISDVFGKVVLKIRSLNSPVIDKR----LKDVLSIVLKSEDILNNSI 2720
            +HPL    VT+     +  K T+    S  +V    IDPLS    L   N    DPLS  +K     SS V+                     EPWS K+  IL+ YTT+EKLSI +SFL     E + I      +  ++ +KVK R EQLD  +E  V+E  NL+ Q++  +I+EL  AL  +W    RVKAL+I IQ +KLL+D + +QF+PSKFVL+TD++D+FG  VYDRL  K+  + S ++ PH+L  NF   ++PE AKET +NWF+K+ASIRELI R Y+EA LL  Y F ++ +  D+L RL  M+RGIG+PL+A YA+ Y+ R+GI + PN ++++   F D + +  ++   +  + L +     ++P YL LF PA+DWILQCL   A++S ++  +    +   S L+++S +++    YI  + + F E+I    ++  PK+ +++ LG C+ ++   G +  L +L+ VWK + KL     +I CA+ W EF+ K+    +IN  L  I+K +T D  Y +F  QLQSI++KI+SC+ DF  L S ++F  ++ MF KE   ++V + +L+ F    I+ +++DPV+I   + + K M+DS+N+L++ D +R +  L+   I  +QF G++ E  L+   + R+ F  ++SV+ ++++ VNNL +  R +  N  H+  +A+FVRAC AF +ITIPS++ +   ++LY  + QVAL+N C  Q ++  K AISLL  +    ++  +        + E   +  S+LL+ PD        NP+    ++YLL+GL+N +        D+   + S  +  +Y ++L +LAA SQ  Y Y   K D+ND++YG    FL     + + + G+++  +++++S    KR    + +++S+++   D+   S+
Sbjct:   30 AHPLKAITVTE--IKNIDKKGTSTPAVSKPTVKQDFIDPLSMVDPLSSGNKAELDPLSTMTKTGP--SSVVTGKPARSDSVKKTDDVGLSDTFEPWSFKKAGILAKYTTSEKLSITTSFLSTSDQERVVIKTQAQTQAGTVSDKVKNRLEQLDDFEEGSVKEMLNLSQQEYVKRIDELNQALISAWDLDHRVKALKIAIQCSKLLADVSVIQFYPSKFVLVTDILDTFGRLVYDRLLDKAQTSLSGTR-PHRLSVNFTSDEVPEAAKETCRNWFFKIASIRELIPRFYVEAALLKSYNFLNTGEYTDALQRLAFMSRGIGDPLVAVYAKCYLCRVGILVAPNFKNHIPQCFEDFIATFHQVQSDSVQNILAVQKL--ELPRYLSLFSPALDWILQCLAHEASESMLNETLERCKQGCNSALMINSIMSAFQPQYIGSRAVAFTELIRDCEDTGLPKHVLHRTLGLCLVVANTPGDQ-QLSVLNEVWKAVVKLKNPAEYISCAEVWIEFVVKDFGKKEINTILGDIIKHLTPDRAYEDFYPQLQSIVSKIMSCQHDFSLLFSLEKFLPFIDMFQKEAIKVDVCKCILESFNKHQIT-TVNDPVVINAMMFLGKIMHDSVNALTLEDEKRTIGNLLCGFIRLVQF-GRDFEQQLSFYVECRAYFSNLDSVLITLLQSVNNLTIETRKIV-NGNHSRKTAAFVRACSAFCFITIPSLQSVFSQLQLYLLSGQVALLNQCYSQGDAFFKAAISLLPDVPKTVDVADSKSKSSEPFLLEYLYNFVSTLLVMPD--------NPDMG--VMYLLRGLLNVL-------QDYTWEQSSDARVLVYTRVLSMLAAASQEQYPYHIDKVDSNDSMYGSDPKFLAEVQAIANTLIGEILSHLKTISSAEFGKRQSSLILEIISVLVAGCDMSVQSV 927

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Match: A0A210QSR7 (UPF0505 protein C16orf62-like OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05618 PE=4 SV=1)

HSP 1 Score: 532.717 bits (1371), Expect = 2.839e-170
Identity = 319/895 (35.64%), Postives = 516/895 (57.65%), Query Frame = 3

Query:   84 SHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVL--IIDPLSANSSLGQINDPLS--------------DTSKIDQVFSSTVSN-----IEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKT-SSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAAS------VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL----LVISDVFGKVVLKIRSLNSPVIDKR 2663
            SHPL    V +   T+           +SK+V   ++DPLS   S  + +DPLS               +S + Q  +   S+      EPW++K+ SIL+ Y+T+EKLSI +SFL     E + I   T +++ +KV+ R EQLD  +E  V+E  NL+ Q + ++I+EL  AL  +W + QRVKAL+I IQ +KLL+DT+ +QF+PSKFVLITD++D+FG  VYDRLK K+      S +P +L DNF   Q+PE AKET +NWFYK+ASIRELI R Y+E  +L CY + +  +  D+L RLM M +GIG+PL+A YAR Y++R+G+ + P   D+L   F+D L S  ++      + L +     ++P YL LF PA+DW+LQC+   +++  +  ++   +   +S LL++S +++    YI  + + F EMI    ++ +PK+ +++ LG C+ ++ +   E  L +L+ VWK + KL     +I  A+ W E++  N    ++N  LA I+K MT D  + ++  QLQS++ K+++   DF  L +  +F  ++ MF KE   +++ + +++ F     S+  +DPV+I     + K M+DS+N+L+++D +++V+ LI   + KI F GK+ E  L+   + RS F  ++ V+  +V+ VNNLA+  R +  N  H+  + +FVRAC A+ +ITIPS++     + LY  + QVAL+N C  QA+SC+K AISL+  +  +  +   +      + E   +  S+LL  PD        NP+    +LYLL+GL+N      IL+N +   + +  K  +Y ++L +L+A SQ  YLY   K DAND +YG    FL     + S +  +++  +++L +P   KR
Sbjct:   29 SHPLKTISVVEVKSTEKRGTPMK-GAGASKAVKTELLDPLS---SALEGSDPLSMFAAEVQTQTASKTRSSSLKQTKTGNPSDDLDETFEPWNAKKASILTKYSTSEKLSITTSFLSASDKERVVIKAVTATTVTDKVRNRLEQLDDFEEGSVQEMLNLSQQDYVNRIDELNQALVSAWDNDQRVKALKIAIQCSKLLADTSVIQFYPSKFVLITDILDTFGRLVYDRLKEKAMYYPPGSGVPVKLPDNFTPDQVPESAKETCRNWFYKIASIRELIPRFYVETAILKCYSYLNQGEYTDALKRLMAMIKGIGDPLVAIYARCYLSRVGMLIAPTISDHLMPCFDDFLVSYAQIQGDYVQNVLAMQKL--EMPKYLTLFSPALDWLLQCIANRSSEQTLMDVLQKFKKHCKSALLLNSIISAFKPEYIAVRAVEFTEMIRESEDTGFPKHLLHRTLGLCLVMT-SPPEEQKLTVLNEVWKAVMKLKNPADYIGSAEIWIEYVVINFKKREVNTILADIIKHMTPDRAFEDYYPQLQSVVAKVVTHIQDFSELFALTKFLPFIDMFQKEAVKVDICKTIMEAFAKHQ-SEPTNDPVIINALTFICKTMHDSVNALTLADEKKMVSHLISNFVLKISF-GKDFEQQLSFYVEARSAFTNLDLVLIQLVQNVNNLAIETRRVV-NGNHSRKTGNFVRACAAYCFITIPSLQSNMAQLHLYLLSGQVALLNQCYSQADSCLKAAISLIPDVPKNLYLDGKTRSSEPFLVEFIYNFLSTLLAVPD--------NPDSG--VLYLLRGLLN------ILQN-YTWEQSTDTKVQIYTRVLALLSATSQEVYLYHVDKVDANDAMYGSDPKFLSEVNAICSTLLEEILNHLKTLATPETFKR 896

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Match: V4B9V8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_195736 PE=4 SV=1)

HSP 1 Score: 526.168 bits (1354), Expect = 8.201e-168
Identity = 332/949 (34.98%), Postives = 527/949 (55.53%), Query Frame = 3

Query:   30 FKERIYKFE-KHCNFTV--TDSHPLIRTCVTQGNFTKVYNKSTNFNENS-------SKSVLIIDPLSANSSLGQI---NDPLSD---------TSKIDQVFSSTVS----------NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLL----SKIEIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENF---LLVISD-VFGKVVLKIRSLNSPVIDKRLK----DVLSIVLKSEDILNNSI 2720
            FK+R Y  E K  +FT   TDSHPL    VT+        KS +  +NS       +  +  IDPL A++ L Q     DPLS          T K    F  T +          N EPWS+K+ +IL+ YTT+EKLSI +SFL     E++ I  +T+S+ +KVK R EQLD  DE  V++  NL+ Q +  +I+EL  AL  +W    RV AL+I IQ +KLL+DT+ + F+PSKFVLITD++D+FG  VYDRL+ K+        +P +    F   Q+PE AKET +NWF+K+ASIRELI R Y+EA L+  Y F  S    ++L RL  M RGIG+PL+A YAR Y+ R+G  + P+   +L    +D L +  ++   +  + L +     ++P YL LF PAVDW+LQC    A+D  +  I+    E   S LLV+S +++    +I  +   F +MI    ++  PK+ +Y+  G C+     +   PA   L +L+ VWK +TKL     +I CA++W EF+AKN    +IN  +  I+K MT D  Y ++  QL S+++KI+  + DF  L S ++F  ++ MF +E   +E  + V + F    + +S +DPV+I   + + K M+DS+N+L++ D +R+++ +I   I +I F G++ E  L+   + RS F  +++V+  +++ VN L+M+ R +     H+  +A+FVRAC A+ +ITIPS++ +   ++LY  + QVAL+N C  Q ++  K AISL+     ++EID    A    + +   +  S++L  PD          N    ++Y+LKGL+N +        D+     S  K  +YI++L +L+A SQ  Y+Y   K D+ND +YG    +   L  ++D +  +++  +++L +P + KR      ++++ ++   DI N S+
Sbjct:    8 FKKRDYDSEAKSESFTPQPTDSHPLKSITVTE------VKKSVHVKKNSQPLANQIADPLGSIDPLGASNPLSQAFEGVDPLSKFAAEVDIPVTKKKSNSFGKTAASDIVEDDLDENFEPWSTKKANILARYTTSEKLSITTSFLSASDKEKVVIKAQTTSVSDKVKNRLEQLDDFDEGSVQQMLNLSQQDYVKRIDELNLALVTAWEKDHRVTALKIAIQCSKLLADTSVIPFYPSKFVLITDILDTFGKLVYDRLREKA------QYIPAE---KFTSDQVPESAKETCRNWFFKIASIRELIPRFYVEAALIKSYNFLKSNDYSEALSRLAYMCRGIGDPLVAAYARCYLCRVGFKVAPSITIHLMPCLDDFLKTFPQIQGDSVQNILAMQKL--EMPRYLTLFSPAVDWLLQCCAHRASDKVLTQILEKCKEQCNSALLVNSIMSAFNPQFIAARSNLFTDMIKECEDTGLPKHLLYRTHGLCL----VMADPPADQKLTVLNDVWKVVTKLKNPSEYIGCAETWIEFVAKNFGKREINTIIGDIIKHMTPDRAYEDYYPQLLSVVSKILVHQHDFSLLFSLEKFMPFIDMFQRETVKVEACKTVAESFDKYQV-ESTNDPVVINAMMFICKTMHDSVNALTLEDEKRVISNMICGFIRQILF-GRDFEQQLSFYVEARSNFSNLDTVLIQLIQSVNKLSMDTRQVVKGN-HSRKTAAFVRACAAYCFITIPSLQSVYSQLQLYLISGQVALLNQCYSQGDAFFKAAISLIPDLPKQMEIDGKTRATEPILIDYILNFISTILTIPD----------NPEAGVMYMLKGLLNVL-------QDYTWDNSSDAKAVVYIRVLALLSAASQESYIYHIDKVDSNDKMYGSDPKYINELKGMADTLINEILSHLKTLATPELGKRQSSIALELVNTIIAHGDITNKSM 915

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Match: A0A091L4Q3 (UPF0505 protein C16orf62 (Fragment) OS=Cathartes aura OX=43455 GN=N323_08766 PE=4 SV=1)

HSP 1 Score: 525.783 bits (1353), Expect = 1.050e-167
Identity = 317/877 (36.15%), Postives = 495/877 (56.44%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSAN-------SSLGQINDPLSDTSKIDQVF--------SSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSK----IEIDRNI-PA-ASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKI 2630
            D HPL    VT+    K+  K +  + +SS S  ++DPLS+        S      DP++ T+ +D           S+  S+ EPWSSKR  IL+ YTT EKLSI     +    E+ +     S++ EKV+TR E+LD ++E   +E  NL  Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT  +QF+PSKFVLITD++D+FG  VY+R+     DN+ +      L DNF    + + AKET  NWF+K+ASIRELI R Y+EA +L C KF     I + L RL  M RGIG+PL+A YAR+Y+ R+G+ + P  ++ L   F D L + K++      ++L +     +IP YL L+ PA+DWILQC+   A +  +  ++   +    + LL++S +++    +I  + + F  MI    ES +PK+ +++ LG    L+ A+   P    LQ+L+  WK +TKL   + +I CA+ W E+  K+    ++N  LA ++K MT D  + +   QLQSI+ K+I+   DF  L S ++F  +L MF KE   +EV + +++ F      +S  DPV++   + + K M+DS+N+L++ D +R++  LI   I  + F G++ E  L+   + RS F  +E V+  ++  VN LAM  R +     H+  +A+FVRAC+AF +ITIPS+  I   + LY  + QVAL N CL QA++  K A+SL+ +    I +D  + P+ A + E   +  S+LL+ PD        +P Q   +L+L++GL+N I        D+   + S  K  +Y  +L +L+A +Q  Y+Y   K D+NDT+YGG   FL  I+ +   V+ +I
Sbjct:   25 DYHPLKPITVTESKTKKMNRKGSTSSTSSSSSSSVMDPLSSVLDGTDPLSLFAAAADPVTTTAAMDSTRKKRDKDDSSAVGSDFEPWSSKRGEILARYTTTEKLSIN----LYMGSEKGKATTAGSAVSEKVRTRLEELDDLEEGSQKELLNLTQQDYMNRIEELNQSLKDAWSSDQKVKALKIVIQCSKLLSDTTVIQFYPSKFVLITDILDTFGKLVYERILSMCVDNRVS------LPDNFSPESVNDTAKETCLNWFFKIASIRELIPRFYVEAAILKCNKFLSKTGISECLPRLTSMIRGIGDPLVAVYARAYLCRVGMEVAPQLKESLNKNFFDFLLTFKQIHGDTVQNQLVVQGV--EIPLYLTLYSPAIDWILQCIAYRAPEVLLTEMMERCKKLGNNALLLNSVMSAFRAEFIAARSMDFIGMIKECDESGFPKHLLFRSLG----LNLALADPPENDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDAYPQLQSIIQKVITYIYDFSLLFSVEKFLPFLDMFQKESVRVEVCKCIMESFIKHE-QESTKDPVILNALLHICKTMHDSVNALTLEDEKRMLAALINGFIKMVSF-GRDFEQQLSFYVEARSMFCNLEPVLVQLIHSVNQLAMETRKVMKG-NHSRKTAAFVRACVAFCFITIPSLSSIFTRLNLYLHSGQVALANQCLSQADAFFKAAVSLVPEVPKMISVDGKMRPSDAFLLEFLCNFFSTLLVVPD--------HPEQG--VLFLVRGLLNVI-------QDYTWEDNSDDKVRIYTNVLHLLSAMTQEAYIYHVDKVDSNDTLYGGDSKFLAEINKLCETVIAQI 865

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 498.434 bits (1282), Expect = 1.621e-160
Identity = 324/921 (35.18%), Postives = 513/921 (55.70%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS-----DTSKIDQVFSSTVS----------------NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA----LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKRLKDV----LSIVLKSEDILNNSI 2720
            D HPL    VT     +   K +  + +SS S + +DPLS   S+ +  DPLS       S++  +  S+ S                + EPWS+KR  ILS +TT EKLSI + F+     E+ +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D       P    D+F    + + AKET  NWF+K+ASIRELI RLY+EA +L C +F +   I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++      ++L I     +IP YL L+ PA+ WILQC+   A D  +  ++   +    + LL++S + +    ++  +   F  MI    E+ +PK+ ++  LG  ++ +     +PA    L +L+  WK +TK+   + +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   +F  L S ++F  ++ MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L+V D +R +  LI   I  + F G++ E  L+   + R+TF  +E+VI  ++  VN LAM  + +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R I   SV     S  + LL F  INS L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  IS     + G+V+  +++L      +R   +     S++L   D+ NN +
Sbjct:   36 DYHPLKPIIVTDSRSRRGGRKGSTSSSSSSSSSVAMDPLS---SMMEGTDPLSLFAAASASEVPTLSHSSSSVELGRKQRENEDEVGADFEPWSAKRGEILSRFTTTEKLSI-NLFM---GSEKNKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVKRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGRLVYERIWSMCSD-------PRPQPDSFSVEDVNDTAKETCLNWFFKIASIRELIPRLYVEAAILKCNRFLNKTGIQETLPRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHSDTVQNQLVIQRV--EIPVYLTLYSPAIHWILQCVAYRAPDVLLTEMMERCKKLGNNALLLNSVMWAFRPEFVAARATDFIGMIKDCDEAGFPKHLLFGSLGRSLACA-----DPAESERLPILNEAWKVITKVRSPQDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVMKKILTYFHNFSVLFSMEKFLPFMDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHVCKTMHDSVNALTVEDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLETVIIQLIHTVNQLAMETKRVMGG-NHSRKTAAFVRACAAYSFITIPSLTSIFSRLHLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRTI---SVEGKQRSSEAFLLDF--INSFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQENYLYTIPKVDSNETLYGGDPKFVAEISRLCETLIGQVLDHLKTLGREEGVRRQGSIAFALFSVLLAHGDLRNNKL 916

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 498.434 bits (1282), Expect = 2.149e-160
Identity = 324/921 (35.18%), Postives = 513/921 (55.70%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS-----DTSKIDQVFSSTVS----------------NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA----LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKRLKDV----LSIVLKSEDILNNSI 2720
            D HPL    VT     +   K +  + +SS S + +DPLS   S+ +  DPLS       S++  +  S+ S                + EPWS+KR  ILS +TT EKLSI + F+     E+ +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D       P    D+F    + + AKET  NWF+K+ASIRELI RLY+EA +L C +F +   I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++      ++L I     +IP YL L+ PA+ WILQC+   A D  +  ++   +    + LL++S + +    ++  +   F  MI    E+ +PK+ ++  LG  ++ +     +PA    L +L+  WK +TK+   + +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   +F  L S ++F  ++ MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L+V D +R +  LI   I  + F G++ E  L+   + R+TF  +E+VI  ++  VN LAM  + +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R I   SV     S  + LL F  INS L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  IS     + G+V+  +++L      +R   +     S++L   D+ NN +
Sbjct:   56 DYHPLKPIIVTDSRSRRGGRKGSTSSSSSSSSSVAMDPLS---SMMEGTDPLSLFAAASASEVPTLSHSSSSVELGRKQRENEDEVGADFEPWSAKRGEILSRFTTTEKLSI-NLFM---GSEKNKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVKRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGRLVYERIWSMCSD-------PRPQPDSFSVEDVNDTAKETCLNWFFKIASIRELIPRLYVEAAILKCNRFLNKTGIQETLPRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHSDTVQNQLVIQRV--EIPVYLTLYSPAIHWILQCVAYRAPDVLLTEMMERCKKLGNNALLLNSVMWAFRPEFVAARATDFIGMIKDCDEAGFPKHLLFGSLGRSLACA-----DPAESERLPILNEAWKVITKVRSPQDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVMKKILTYFHNFSVLFSMEKFLPFMDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHVCKTMHDSVNALTVEDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLETVIIQLIHTVNQLAMETKRVMGG-NHSRKTAAFVRACAAYSFITIPSLTSIFSRLHLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRTI---SVEGKQRSSEAFLLDF--INSFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQENYLYTIPKVDSNETLYGGDPKFVAEISRLCETLIGQVLDHLKTLGREEGVRRQGSIAFALFSVLLAHGDLRNNKL 936

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 497.278 bits (1279), Expect = 3.988e-160
Identity = 324/921 (35.18%), Postives = 513/921 (55.70%), Query Frame = 3

Query:   81 DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLS-----DTSKIDQVFSSTVS----------------NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA----LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKRLKDV----LSIVLKSEDILNNSI 2720
            D HPL    VT     +   K +  + +SS S + +DPLS   S+ +  DPLS       S++  +  S+ S                + EPWS+KR  ILS +TT EKLSI + F+     E+ +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D       P    D+F    + + AKET  NWF+K+ASIRELI RLY+EA +L C +F +   I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++      ++L I     +IP YL L+ PA+ WILQC+   A D  +  ++   +    + LL++S + +    ++  +   F  MI    E+ +PK+ ++  LG  ++ +     +PA    L +L+  WK +TK+   + +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   +F  L S ++F  ++ MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L+V D +R +  LI   I  + F G++ E  L+   + R+TF  +E+VI  ++  VN LAM  + +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R I   SV     S  + LL F  INS L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  IS     + G+V+  +++L      +R   +     S++L   D+ NN +
Sbjct:   42 DYHPLKPIIVTDSRSRRGGRKGSTSSSSSSSSSVAMDPLS---SMMEGTDPLSLFAAASASEVPTLSHSSSSVELGRKQRENEDEVGADFEPWSAKRGEILSRFTTTEKLSI-NLFM---GSEKNKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVKRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGRLVYERIWSMCSD-------PRPQPDSFSVEDVNDTAKETCLNWFFKIASIRELIPRLYVEAAILKCNRFLNKTGIQETLPRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHSDTVQNQLVIQRV--EIPVYLTLYSPAIHWILQCVAYRAPDVLLTEMMERCKKLGNNALLLNSVMWAFRPEFVAARATDFIGMIKDCDEAGFPKHLLFGSLGRSLACA-----DPAESERLPILNEAWKVITKVRSPQDYINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVMKKILTYFHNFSVLFSMEKFLPFMDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHVCKTMHDSVNALTVEDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLETVIIQLIHTVNQLAMETKRVMGG-NHSRKTAAFVRACAAYSFITIPSLTSIFSRLHLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRTI---SVEGKQRSSEAFLLDF--INSFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQENYLYTIPKVDSNETLYGGDPKFVAEISRLCETLIGQVLDHLKTLGREEGVRRQGSIAFALFSVLLAHGDLRNNKL 922

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 267.7 bits (683), Expect = 7.879e-76
Identity = 167/429 (38.93%), Postives = 247/429 (57.58%), Query Frame = 3

Query:    9 NLI*MINFKERIYKFE---KHCNFTVT-----DSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTS---------KIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIEST 1238
            NL   + +  R+ K+    + C    T     D HPL    VT     +   K +  + +SS S + +DPLS   S+ +  DPLS  +         K  +      ++ EPWS+KR  ILS +TT EKLSI + F+     E+ +  + +S++ EKV+TR E+LD ++E   RE  NL+ Q +  +I EL  +LK +W   Q+VKAL+I+IQ +KLLSDT+ +QF+PSKFVLITD++D+FG  VY+R+     D       P    D+F    + + AKET  NWF+K+ASIRELI RLY+EA +L C +F +   I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L S +++      ++L I     +IP YL L+ PA+ WILQC+   A D  I+     +E T
Sbjct:    4 NLCIAVKWHARVRKYGAELQRCQLEATPVEQGDYHPLKPIIVTDSRSRRGGRKGSTSSSSSSSSSVAMDPLS---SMMEGTDPLSLFAAASASELGRKQRENEDEVGADFEPWSAKRGEILSRFTTTEKLSI-NLFM---GSEKNKASSPSSAVSEKVRTRLEELDDLEEGSQRELLNLSQQDYVKRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTSVIQFYPSKFVLITDILDTFGRLVYERIWSMCSD-------PRPQPDSFSVEDVNDTAKETCLNWFFKIASIRELIPRLYVEAAILKCNRFLNKTGIQETLPRLTAMIRGIGDPLVAVYARAYLCRVGMEVAPHLKDSLNKNFFDLLASFRQIHSDTVQNQLVIQRV--EIPVYLTLYSPAIHWILQCVAYRAPDDYINCAEIWVEFT 416

HSP 2 Score: 221.476 bits (563), Expect = 7.649e-60
Identity = 145/427 (33.96%), Postives = 234/427 (54.80%), Query Frame = 3

Query: 1479 FIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVL-----VAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVIS----DVFGKVVLKIRSLNSPVIDKRLKDV----LSIVLKSEDILNNSI 2720
            +I CA+ W EF  ++    ++N  LA I+K MT D  + +   QLQS++ KI++   +F  L S ++F  ++ MF K+   +EV + +++ F      +   DPV++   + + K M+DS+N+L+V D +R +  LI   I  + F G++ E  L+   + R+TF  +E+VI  ++  VN LAM  + +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL QA++ +K A+S+L   E+ R I   SV     S  + LL F  INS L     V ++P Q   +LYL++GL+N +        D+   + S  K  +YI  L +LAA SQ  YLY   K D+N+T+YGG   F+  IS     + G+V+  +++L      +R   +     S++L   D+ NN +
Sbjct:  405 YINCAEIWVEFTCRHFTKREVNTVLADIIKHMTPDRAFEDAYPQLQSVMKKILTYFHNFSVLFSMEKFLPFMDMFQKDSVRVEVCKSIMEVFIKHQ-QEPTRDPVILNALLHVCKTMHDSVNALTVEDEKRSLALLINGFIRMVSF-GRDFEQQLSFCVEARATFCNLETVIIQLIHTVNQLAMETKRVMGG-NHSRKTAAFVRACAAYSFITIPSLTSIFSRLHLYLLSGQVALANQCLSQADAFLKAAVSILP--EVPRTI---SVEGKQRSSEAFLLDF--INSFLSTLLVVPDHPEQG--VLYLVRGLLNMV-------QDYTWEDNSDAKVRVYISALPLLAAMSQENYLYTIPKVDSNETLYGGDPKFVAEISRLCETLIGQVLDHLKTLGREEGVRRQGSIAFALFSVLLAHGDLRNNKL 812

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001174.1 (pep scaffold:Pmarinus_7.0:GL481430:14062:21415:1 gene:ENSPMAG00000001046.1 transcript:ENSPMAT00000001174.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 229.95 bits (585), Expect = 2.056e-67
Identity = 117/296 (39.53%), Postives = 184/296 (62.16%), Query Frame = 3

Query:  195 LSANSSLGQINDPLSDTSKIDQVFSSTV-SNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEV-RETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRL 1076
            +++   LG + DP  D  +  +  S+ + S+ + W+ KR  IL+ YTT EKLS+  S      D++       +++ EKV++R E+LD ++E   RE  NL+ Q++  ++ E   AL+ +W   Q+VKAL+I+IQ +KLLSDT+ + F+PSKFVLITD++D+FG  V+DR+    C+       P    D+ R   +P+ A+ET  NWFYK+ASIREL+ RLY+EA +L C +F  +    + L RL  M RG+G+PL+A +AR+Y+ R+G+   P+ R+ L   F D L + K++
Sbjct:   96 MASAEPLGAVGDPNRDGEQRKRGASTGLGSDFQSWAQKRPEILARYTTVEKLSLRLSM---GADKDSGRHGAGAAVPEKVRSRLEELDDLEEGSQREMLNLSTQEYVGRVEEQGQALREAWATDQKVKALKIVIQCSKLLSDTSVISFYPSKFVLITDILDTFGRLVHDRI-WAMCNEGRPPGAPALSPDSIRPELVPDSARETCLNWFYKIASIRELVPRLYVEAAILRCSRFVKASGFEEVLPRLAAMLRGVGDPLVAMFARAYICRVGVEGAPHLRELLTCNFFDFLLTFKQV 387

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Sea Lamprey
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:563454])

HSP 1 Score: 201.06 bits (510), Expect = 1.739e-56
Identity = 130/386 (33.68%), Postives = 211/386 (54.66%), Query Frame = 3

Query: 1536 QINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNV-RSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNI----PAASVTEMAASLASSLLMFPDINSVLVAENPNQNQH-MLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL----LVISDVFGKVVLKIRSLNSPVIDKR 2663
            ++N  LA I+K MT D  + E   QLQSI+++++    DF  L +  +F  +L MF KE   +EV ++V + F      ++  DPV++   + + K M+DS+N+LS+ D RR+++      I  I F G++ E  L+   + R+TF  +E V+ +++  VN LAM   R +R N  H   +A+FVRAC A+ +ITIPS+  +   + LY  + QVAL N CL QA+   K AI+LL  +E+ R++     A     M     SS L     +++LV   P   +H +LYL++GL+N +        D+   E S  +   Y+ ++ +LAA SQ  YLY   K D+ND++YG    FL     +   + G+V+ +++ L    ++KR
Sbjct:    3 EVNTVLADIIKHMTPDRAFEEAYPQLQSIVSRVLKYFQDFSTLFAMDKFLPFLDMFQKELVKVEVCKMVTEAFIKHQQEET-RDPVIVNALMSVCKTMHDSVNALSLDDERRVISAFTCGFIRMISF-GRDFEQQLSFYVEARATFTNLEPVLVALMHSVNRLAMETCRLVRGN--HTRKTAAFVRACAAYCFITIPSLTSVFAQLILYLLSGQVALANQCLSQADGFFKAAIALL--VEVPRSVMVDGKARPTEPMLLEFLSSFL-----STLLVV--PXHPEHSVLYLVRGLLNVL-------QDYTWEEGSDGRARAYLSVMHLLAAASQETYLYSISKVDSNDSLYGSDPKFLGEVDRLCETILGQVLDQLKLLGKQEVNKR 368

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Nematostella
Match: EDO40081 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8D2])

HSP 1 Score: 505.753 bits (1301), Expect = 4.159e-165
Identity = 288/789 (36.50%), Postives = 450/789 (57.03%), Query Frame = 3

Query:  255 DQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASI-ESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEP---ALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKI----EIDRNIPAAS--VTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFL 2588
            D V S      EPWSSK+  IL+ YTT+EKLSI +  ++ K         + +++++KVK R EQLD  +E  V+E  NL+ Q +  +I EL  AL  +W   QRVKAL+I IQ  KLL+DT+ +QF+PSKFVL+TD++D+FG  VY+RL  KS      S +P  L + F   Q+P+ AKET +NWFYK+ASIREL+ R Y+E  +L CY F    +   +L+RL KM RG+G+PL+A YAR Y+ R+GI + P+ +++L       +   K+L      + L +   +    YL+L+ PA+DW+LQC+  G  +S +  I+    E   S LL++S + +    YI ++ L F ++I    E+ +PK+ +Y+ LG    L+  I   P    L +LS VWK + KL     +I CA+ W E+  ++    +IN  +  ++K M  D  + +F  QL SI++KI+    DF  L+S  +F  +L MF KE   ++  +++++ F      +  +DP++    + + K ++DS+N+L++ D RR++  LI   + K  F G++ E  L+     R++F  +++V+ ++V+RVN LAM  R +     H+  +ASFVRAC A+ +ITIPSIEDI   ++LY  + QVAL N  L QA+S  K AISL+  +    E+D  + A+   +     +  S+LL+ PD        NP     +LYL++GL++ +        D      S  K  LY+  + +L+A  Q  YLY   K D+ND +YGG + F+
Sbjct:    3 DAVDSGDDDTFEPWSSKKTGILAKYTTSEKLSITTVSVVIK---------QQTTVVDKVKHRLEQLDDFEEGSVKEMLNLSQQDYVKRIEELNQALISAWESDQRVKALKIAIQCAKLLADTSVIQFYPSKFVLVTDILDTFGRLVYERLHRKSSMFTPGSSVPVMLPEKFTPDQVPQSAKETCRNWFYKIASIRELVPRFYVEIAILKCYNFLTQGEFSQALVRLTKMLRGVGDPLVAIYARCYICRVGILVAPDVKEHLIENLYSFITCYKQLQSDTVQNTLAVQRLEMH-QYLQLYPPALDWVLQCVAHGTPESTLTDILERCKEECNSALLLNSIILAFKPEYITQRALLFTDLIKNCEEAGFPKHHLYRSLG----LNLIICDPPEEQKLPILSEVWKVVMKLKNPGEYISCAEVWVEYPCRHFTKREINTLIGDVIKHMLPDRAFEQFYPQLLSIVSKILDNVHDFSVLVSMDKFLPFLDMFQKESIKVDACKMIMEAFVKYQ-HEPTTDPMVQNALMFVCKTLHDSVNALTMEDERRVIGNLITGYLKKTDF-GRDFEKQLDFYVDTRASFSNLDAVLVTLVQRVNFLAMRTRDIVKG-NHSRKTASFVRACAAYCFITIPSIEDIFTKLQLYLYSGQVALANQALSQADSFFKAAISLVPDVPRNLEVDSKLKASEPYLINFLNNFLSTLLVVPD--------NPETG--VLYLVRGLLDVV-------TDFSWELNSDAKMSLYLNAICLLSAMCQDTYLYHIDKVDSNDKLYGGDKKFI 757

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BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Medaka
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:101160148])

HSP 1 Score: 482.256 bits (1240), Expect = 2.052e-154
Identity = 290/831 (34.90%), Postives = 475/831 (57.16%), Query Frame = 3

Query:  282 NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPD--INSVLVAENPNQNQH-MLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISD----VFGKVVLKIRSLNSPVIDKRLKDVL-----SIVLKSEDILNNSI 2720
            + EPW+ KR  IL+ +TT EKLSI    L    ++   +   +S++ EKV+TR E+LD ++E   +E  NL+ Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDTA +QF+PSKFVLITD++D+FG  VYDR+     D       P  L ++F    + + AKET  NWF+K+ASIREL+ RLY+EA +L C +F     I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L + +++   +  ++L +     ++P YL L+ PA++WILQC+   A +  +  ++   ++   + LL++S + +    ++  +   F  MI    ES +PK+ ++  LG     S A    P    L +L+  WK +TK+   + +I CA+ W EF  ++    ++N  LA I+K +T D  + +   QLQS++ +I++   DF  L S + F  +L MF K+   +EV + +++ F    + +   DPV++   + + K M+DS+N+L++ D +R +  LI+  +  + F G++ E  L+   + R+ F  +E V+  +V  VN LAM  R +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL Q+++ +K A+SLL   E+  +I   SV     S    LL F +  + ++LV   P+  +H +LYL++GL+N +        D+   E S  K  +YI  L +LAA SQ  +LY   K D+N+T+YGG   FL  I+     + G+++  +++L       R +  L     +++L   D+ NN +
Sbjct:  118 DFEPWAMKRGEILARFTTTEKLSI---NLCMGSEKGKALGPGSSAVSEKVRTRLEELDDLEEGSQKELLNLSQQDYANRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTAVIQFYPSKFVLITDILDTFGRLVYDRIWSMCSD-------PRPLPESFTVEDVNDTAKETCLNWFFKIASIRELLPRLYVEAAILKCNRFLSRTGIQETLPRLTAMIRGIGDPLVAAYARAYLCRVGVEVAPHLKDSLNRNFFDLLSAFRQIGGESVQNQLVVQRV--EVPEYLTLYSPAINWILQCIAYRAPEVLLTEMMDRCKTMANNALLLNSIMRAFRPEFVAARATDFIGMIKDCDESGFPKHLLFGSLGR----SLACADPPESERLTILNEAWKVITKVRSPQDYIGCAEVWVEFTCRHFTKREVNTVLADIIKHLTPDRAFEDAYAQLQSVIGRILTYFHDFSVLFSMERFLPFLDMFQKDSVRVEVCKSIMEVFIKHQL-ELTRDPVILNAMLHICKTMHDSVNALTLEDEKRSLALLIVGFLRTVSF-GRDFEQQLSFCVEARAAFCNLEPVLVQLVHTVNTLAMETRRVMQG-SHSRKTAAFVRACAAYSFITIPSLGSIFTRLHLYLLSGQVALANQCLSQSDAFLKAAVSLLP--EVPHSI---SVEGKLRSSEGFLLDFINNFLATLLVV--PDHPEHGVLYLVRGLLNMV-------QDYTWEENSDAKVRVYIGALPLLAAMSQEAFLYSIPKVDSNETLYGGDPKFLSEINKLSETLIGQILDHLKALARDEQSARRQSALAFSLFAVLLAHGDLRNNKL 915

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Medaka
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:101160148])

HSP 1 Score: 482.256 bits (1240), Expect = 2.244e-154
Identity = 291/831 (35.02%), Postives = 473/831 (56.92%), Query Frame = 3

Query:  282 NIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDE-EVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIP-YLKLFVPAVDWILQCLCCGATDSQIDSIVASIES-TQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPA---LQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVA--ENPNQNQH-MLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISD----VFGKVVLKIRSLNSPVIDKRLKDVL-----SIVLKSEDILNNSI 2720
            + EPW+ KR  IL+ +TT EKLSI    L    ++   +   +S++ EKV+TR E+LD ++E   +E  NL+ Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDTA +QF+PSKFVLITD++D+FG  VYDR+     D       P  L ++F    + + AKET  NWF+K+ASIREL+ RLY+EA +L C +F     I ++L RL  M RGIG+PL+A YAR+Y+ R+G+ + P+ +D L   F D+L + +++   +  ++L +     ++P YL L+ PA++WILQC+   A +  +  ++   ++   + LL++S + +    ++  +   F  MI    ES +PK+ ++  LG     S A    P    L +L+  WK +TK+   + +I CA+ W EF  ++    ++N  LA I+K +T D  + +   QLQS++ +I++   DF  L S + F  +L MF K+   +EV + +++ F    + +   DPV++   + + K M+DS+N+L++ D +R +  LI+  +  + F G++ E  L+   + R+ F  +E V+  +V  VN LAM  R +     H+  +A+FVRAC A+S+ITIPS+  I   + LY  + QVAL N CL Q+++ +K A+SLL   E+  +I   SV     S    LL F  IN+ L      P+  +H +LYL++GL+N +        D+   E S  K  +YI  L +LAA SQ  +LY   K D+N+T+YGG   FL  I+     + G+++  +++L       R +  L     +++L   D+ NN +
Sbjct:  119 DFEPWAMKRGEILARFTTTEKLSI---NLCMGSEKGKALGPGSSAVSEKVRTRLEELDDLEEGSQKELLNLSQQDYANRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTAVIQFYPSKFVLITDILDTFGRLVYDRIWSMCSD-------PRPLPESFTVEDVNDTAKETCLNWFFKIASIRELLPRLYVEAAILKCNRFLSRTGIQETLPRLTAMIRGIGDPLVAAYARAYLCRVGVEVAPHLKDSLNRNFFDLLSAFRQIGGESVQNQLVVQRV--EVPEYLTLYSPAINWILQCIAYRAPEVLLTEMMDRCKTMANNALLLNSIMRAFRPEFVAARATDFIGMIKDCDESGFPKHLLFGSLGR----SLACADPPESERLTILNEAWKVITKVRSPQDYIGCAEVWVEFTCRHFTKREVNTVLADIIKHLTPDRAFEDAYAQLQSVIGRILTYFHDFSVLFSMERFLPFLDMFQKDSVRVEVCKSIMEVFIKHQL-ELTRDPVILNAMLHICKTMHDSVNALTLEDEKRSLALLIVGFLRTVSF-GRDFEQQLSFCVEARAAFCNLEPVLVQLVHTVNTLAMETRRVMQG-SHSRKTAAFVRACAAYSFITIPSLGSIFTRLHLYLLSGQVALANQCLSQSDAFLKAAVSLLP--EVPHSI---SVEGKLRSSEGFLLDF--INNFLATLLVVPDHPEHGVLYLVRGLLNMV-------QDYTWEENSDAKVRVYIGALPLLAAMSQEAFLYSIPKVDSNETLYGGDPKFLSEINKLSETLIGQILDHLKALARDEQSARRQSALAFSLFAVLLAHGDLRNNKL 916

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Medaka
Match: vps35l (VPS35 endosomal protein sorting factor like [Source:NCBI gene;Acc:101160148])

HSP 1 Score: 125.176 bits (313), Expect = 1.142e-31
Identity = 73/168 (43.45%), Postives = 108/168 (64.29%), Query Frame = 3

Query:  189 DPLS--ANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEV-RETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGS 683
            DPLS  A +S GQ   P     + ++   +   + EPW+ KR  IL+ +TT EKLSI    L    ++   +   +S++ EKV+TR E+LD ++E   +E  NL+ Q + ++I EL  +LK +W   Q+VKAL+I+IQ +KLLSDTA +QF+PSKFVLITD++D+FG 
Sbjct:   78 DPLSMFAATSAGQ--PPDLGRRRREKEEEAVGPDFEPWAMKRGEILARFTTTEKLSIN---LCMGSEKGKALGPGSSAVSEKVRTRLEELDDLEEGSQKELLNLSQQDYANRIEELNQSLKEAWASDQKVKALKIVIQCSKLLSDTAVIQFYPSKFVLITDILDTFGG 240

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Planmine SMEST
Match: SMESG000014275.1 (SMESG000014275.1)

HSP 1 Score: 1851.25 bits (4794), Expect = 0.000e+0
Identity = 906/906 (100.00%), Postives = 906/906 (100.00%), Query Frame = 3

Query:   21 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 2738
            MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL
Sbjct:  128 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 1033

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Planmine SMEST
Match: SMESG000014275.1 (SMESG000014275.1)

HSP 1 Score: 1850.87 bits (4793), Expect = 0.000e+0
Identity = 906/906 (100.00%), Postives = 906/906 (100.00%), Query Frame = 3

Query:   21 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 2738
            MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL
Sbjct:    1 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 906

[Close]

BLAST of VPS35 endosomal protein sorting factor-like vs. Planmine SMEST
Match: SMESG000014275.1 (SMESG000014275.1)

HSP 1 Score: 1850.1 bits (4791), Expect = 0.000e+0
Identity = 906/906 (100.00%), Postives = 906/906 (100.00%), Query Frame = 3

Query:   21 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 2738
            MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL
Sbjct:  133 MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSSKSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSILSTYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEEVRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTAAVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRETQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSLMRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLKRLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIVASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYKQLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAKNLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLSSQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRMLKEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRSTFGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITIPSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIPAASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLCPILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYGGSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSIYKDWFL 1038

The following BLAST results are available for this feature:

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Celegans
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Fly
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Zebrafish
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Sea Lamprey
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Yeast
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Nematostella
BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Medaka
BLAST of VPS35 endosomal protein sorting factor-like vs. Planmine SMEST

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VPS35L	3.187e-160	36.26	VPS35 endosomal protein sorting factor like [Sourc...	[more]
VPS35L	2.428e-159	36.26	VPS35 endosomal protein sorting factor like [Sourc...	[more]
VPS35L	2.428e-159	36.26	VPS35 endosomal protein sorting factor like [Sourc...	[more]
VPS35L	4.600e-127	33.83	VPS35 endosomal protein sorting factor like [Sourc...	[more]
VPS35L	5.148e-113	34.62	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
F26G1.1	9.330e-37	23.27	pep chromosome:WBcel235:II:4791620:4795643:1 gene:...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
CG8202	1.297e-113	30.80	gene:FBgn0037622 transcript:FBtr0081914	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
vps35l	1.964e-160	36.08	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pcsk7	5.429e-165	35.54	proprotein convertase subtilisin/kexin type 7 [Sou...	[more]
pcsk7	2.852e-158	35.54	proprotein convertase subtilisin/kexin type 7 [Sou...	[more]
pcsk7	7.952e-157	35.20	proprotein convertase subtilisin/kexin type 7 [Sou...	[more]
pcsk7	1.358e-155	35.07	proprotein convertase subtilisin/kexin type 7 [Sou...	[more]
pcsk7	1.425e-155	35.13	proprotein convertase subtilisin/kexin type 7 [Sou...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Vps35l	4.870e-160	34.79	VPS35 endosomal protein sorting factor like [Sourc...	[more]
Vps35l	1.005e-150	34.03	VPS35 endosomal protein sorting factor like [Sourc...	[more]
Vps35l	1.273e-113	32.39	VPS35 endosomal protein sorting factor like [Sourc...	[more]
Vps35l	3.365e-62	43.30	VPS35 endosomal protein sorting factor like [Sourc...	[more]
Vps35l	1.564e-35	42.59	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8BWQ6\|VP35L_MOUSE	1.406e-159	34.79	VPS35 endosomal protein sorting factor-like OS=Mus...	[more]
sp\|A4VCH4\|VP35L_DANRE	1.483e-159	36.08	VPS35 endosomal protein sorting factor-like OS=Dan...	[more]
sp\|Q7Z3J2\|VP35L_HUMAN	1.531e-159	36.26	VPS35 endosomal protein sorting factor-like OS=Hom...	[more]
sp\|Q5R8N4\|VP35L_PONAB	4.144e-159	36.14	VPS35 endosomal protein sorting factor-like OS=Pon...	[more]
sp\|Q5XI83\|VP35L_RAT	9.072e-149	34.77	VPS35 endosomal protein sorting factor-like OS=Rat...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3I576	1.822e-175	37.08	UPF0505 protein C16orf62 homolog OS=Lingula unguis...	[more]
A0A0B7AIC1	6.118e-172	34.77	Uncharacterized protein (Fragment) OS=Arion vulgar...	[more]
A0A210QSR7	2.839e-170	35.64	UPF0505 protein C16orf62-like OS=Mizuhopecten yess...	[more]
V4B9V8	8.201e-168	34.98	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
A0A091L4Q3	1.050e-167	36.15	UPF0505 protein C16orf62 (Fragment) OS=Cathartes a...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
vps35l	1.621e-160	35.18	VPS35 endosomal protein sorting factor like [Sourc...	[more]
vps35l	2.149e-160	35.18	VPS35 endosomal protein sorting factor like [Sourc...	[more]
vps35l	3.988e-160	35.18	VPS35 endosomal protein sorting factor like [Sourc...	[more]
vps35l	7.879e-76	38.93	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000001174.1	2.056e-67	39.53	pep scaffold:Pmarinus_7.0:GL481430:14062:21415:1 g...	[more]
vps35l	1.739e-56	33.68	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40081	4.159e-165	36.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
vps35l	2.052e-154	34.90	VPS35 endosomal protein sorting factor like [Sourc...	[more]
vps35l	2.244e-154	35.02	VPS35 endosomal protein sorting factor like [Sourc...	[more]
vps35l	1.142e-31	43.45	VPS35 endosomal protein sorting factor like [Sourc...	[more]

BLAST of VPS35 endosomal protein sorting factor-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000014275.1	0.000e+0	100.00	SMESG000014275.1	[more]
SMESG000014275.1	0.000e+0	100.00	SMESG000014275.1	[more]
SMESG000014275.1	0.000e+0	100.00	SMESG000014275.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30032674 ID=SMED30032674|Name=VPS35 endosomal protein sorting factor-like|organism=Schmidtea mediterranea sexual|type=transcript|length=2962bp
TCTATATAAATCTTATATGAATGATTAATTTCAAAGAAAGAATATACAAA
TTTGAAAAACATTGTAATTTTACTGTGACTGATAGTCATCCTCTAATAAG
AACATGTGTAACTCAAGGAAACTTCACCAAAGTTTATAATAAATCAACAA
ATTTTAACGAAAATTCTTCCAAGAGTGTTTTAATTATTGATCCACTTTCG
GCCAATTCTTCTTTGGGTCAAATTAATGATCCTTTAAGTGACACAAGTAA
GATTGATCAAGTTTTTTCTTCTACCGTTAGCAACATTGAGCCATGGTCGT
CAAAGAGAATGTCTATTTTGTCAACTTACACTACTAATGAAAAATTAAGT
ATAATTAGTAGCTTTTTAATAAAAAAACCCGACGAAGAAATCAGAATATT
AAATAAAACAAGTTCGATAATCGAAAAAGTGAAAACTCGTTTCGAACAAC
TTGATCAAGTAGACGAAGAAGTAAGAGAAACCTGCAATTTAAATGTTCAA
CAATTCACCGATAAAATCAATGAATTACAAAATGCTCTGAAAATTTCGTG
GCGTGACGGTCAACGAGTGAAAGCACTTCAGATAATTATCCAGAGTACAA
AACTGTTATCGGATACTGCTGCAGTTCAATTTTTCCCGAGTAAATTTGTC
CTAATCACTGACTTGGTGGACAGTTTTGGGTCTTACGTTTATGATCGATT
GAAACTGAAATCGTGTGATAATAAATCGAATTCGAAACTTCCTCATCAAT
TACAGGACAACTTTCGAGAAACCCAAATTCCCGAGGTGGCAAAAGAAACC
GCTCAAAATTGGTTTTACAAAGTCGCATCGATTCGGGAATTAATCGCCCG
ATTGTATATCGAAGCGTGTTTGTTGCCGTGTTACAAGTTTTTCGATTCGA
AACAAATTCCCGACTCTCTGATGCGGTTGATGAAAATGGCCAGAGGAATT
GGAAATCCGTTATTGGCCACGTATGCCCGATCGTATGTGGCTCGAATCGG
AATCGCATTGGAACCGAATCGGCGAGATTATCTCCAATTAGCTTTCAATG
ACATTCTCGATTCACTGAAACGATTGACCGATTCAAACGAGCTCGATAAA
CTGAAAATCGATTCCACTGACAAACAAATTCCCTATTTGAAATTGTTCGT
GCCGGCCGTCGATTGGATATTGCAATGTTTATGTTGCGGAGCGACAGATT
CGCAAATCGACTCGATTGTCGCCAGTATCGAGTCGACCCAAAGTCCATTA
CTCGTCCATTCGGCGCTGAATTCAATTGCCACGAGTTACATTGAAAAGAA
ACCGCTCTATTTTGCCGAAATGATTCATCGATTACCGGAATCGAGTTATC
CGAAATATTCCATGTATAAACAGTTGGGAGCTTGCGTTTCGTTGTCATTC
GCTATCGGACATGAGCCAGCGTTACAGTTGCTGTCATTTGTGTGGAAATA
TATGACGAAATTGAGTGAAGCGCGTTATTTCATAGAATGTGCCGATTCAT
GGGCGGAATTTCTGGCGAAAAATCTCAACACTGTTCAAATCAATAAATAT
TTGGCGCACATTGTCAAGGAAATGACACGCGACAATCAATATCTGGAGTT
TTCCAATCAATTGCAATCGATACTCAACAAAATCATTAGCTGCAAGTGTG
ATTTTGAGAATTTACTTTCATCTCAAGAATTCACTCTATACCTTGCAATG
TTTGACAAAGAACCTTCTTTAATAGAAGTTCGTCAAATAGTGTTGGATAG
ATTTTTTAATTCGAATATCAGTGACTCTTTATCAGATCCGGTGTTGATAC
AAACCTGTATTCGAATGCTGAAAGAGATGTATGATTCACTAAATTCTTTG
AGTGTTTCCGATAACAGAAGAATAGTTACTCGCTTGATTTTAACATTAAT
TAATAAAATTCAATTTGAAGGGAAAAATGTCGAAGATTATTTGAATTTAT
TAACTCAATTTCGAAGTACATTTGGTGGCATAGAATCGGTTATTTTTAGC
ATTGTCGAACGTGTCAACAATTTGGCTATGAATGTGAGATCATTACGACC
GAATCGCGAACATAATTCAGGGAGCGCATCATTTGTCCGAGCTTGTATGG
CATTCAGTTACATAACAATTCCAAGTATCGAAGATATTTCTCTGACTATA
AGGCTTTATACAAGCACAGCTCAAGTTGCATTGGTTAATGGTTGCCTAGG
CCAAGCTGAATCATGTGTCAAAGAAGCTATTAGTTTATTATCAAAAATTG
AAATTGATCGAAATATTCCAGCTGCATCTGTAACAGAAATGGCTGCATCT
TTAGCATCATCTCTATTGATGTTTCCAGACATAAATTCCGTTCTTGTAGC
TGAAAATCCCAATCAGAATCAGCATATGTTATATTTGTTGAAAGGTCTAA
TCAACGCTATAAATCTTTGTCCGATTCTTAAAAATGATCATGTTCCAACT
GAAAAATCCATAATTAAGGGAGACTTATATATTAAGATATTACTTATACT
GGCTGCATTTAGTCAGCCGTATTATTTATATCGTGCCGGTAAAACAGATG
CTAACGATACGATTTACGGTGGTTCCGAAAATTTCTTATTGGTAATTTCC
GATGTTTTCGGTAAAGTTGTGTTGAAAATTCGATCACTAAATTCCCCAGT
TATTGATAAACGACTAAAAGATGTTTTGTCGATTGTTTTAAAATCAGAAG
ATATACTCAACAACTCTATATATAAAGATTGGTTTTTATAAAGATAGTTT
ATACAAATTTGATTTCACATTGAATAATTTTACTTTTCTATCTGTACAAT
AACTGTTTTCAAATGTGATTTTATTGGTTGATTCTTTGTCGAACAATTCG
CCGGGTTTCGTTTAAAATTATTGTTAATTACACTTACACACACATATATA
CATAAATACGTAAATCAACGTATTGGAATTTATTTTTATTGAAAAATCAA
TGGATTTCACCC

protein sequence of SMED30032674-orf-1

>SMED30032674-orf-1 ID=SMED30032674-orf-1|Name=SMED30032674-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=907bp
MINFKERIYKFEKHCNFTVTDSHPLIRTCVTQGNFTKVYNKSTNFNENSS
KSVLIIDPLSANSSLGQINDPLSDTSKIDQVFSSTVSNIEPWSSKRMSIL
STYTTNEKLSIISSFLIKKPDEEIRILNKTSSIIEKVKTRFEQLDQVDEE
VRETCNLNVQQFTDKINELQNALKISWRDGQRVKALQIIIQSTKLLSDTA
AVQFFPSKFVLITDLVDSFGSYVYDRLKLKSCDNKSNSKLPHQLQDNFRE
TQIPEVAKETAQNWFYKVASIRELIARLYIEACLLPCYKFFDSKQIPDSL
MRLMKMARGIGNPLLATYARSYVARIGIALEPNRRDYLQLAFNDILDSLK
RLTDSNELDKLKIDSTDKQIPYLKLFVPAVDWILQCLCCGATDSQIDSIV
ASIESTQSPLLVHSALNSIATSYIEKKPLYFAEMIHRLPESSYPKYSMYK
QLGACVSLSFAIGHEPALQLLSFVWKYMTKLSEARYFIECADSWAEFLAK
NLNTVQINKYLAHIVKEMTRDNQYLEFSNQLQSILNKIISCKCDFENLLS
SQEFTLYLAMFDKEPSLIEVRQIVLDRFFNSNISDSLSDPVLIQTCIRML
KEMYDSLNSLSVSDNRRIVTRLILTLINKIQFEGKNVEDYLNLLTQFRST
FGGIESVIFSIVERVNNLAMNVRSLRPNREHNSGSASFVRACMAFSYITI
PSIEDISLTIRLYTSTAQVALVNGCLGQAESCVKEAISLLSKIEIDRNIP
AASVTEMAASLASSLLMFPDINSVLVAENPNQNQHMLYLLKGLINAINLC
PILKNDHVPTEKSIIKGDLYIKILLILAAFSQPYYLYRAGKTDANDTIYG
GSENFLLVISDVFGKVVLKIRSLNSPVIDKRLKDVLSIVLKSEDILNNSI
YKDWFL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000499	cell
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0003116	parenchymal cell

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0005829	cytosol
GO:0005768	endosome
GO:0005769	early endosome
GO:0030904	retromer complex

Vocabulary: **biological process**
Term	Definition
GO:0032456	endocytic recycling
GO:1990126	retrograde transport, endosome to plasma membrane
GO:0006810	transport
GO:0015031	protein transport
GO:0042147	retrograde transport, endosome to Golgi

Vocabulary: **INTERPRO**
Term	Definition
IPR029705	VPS35L
IPR015155	PFU

Vocabulary: **molecular function**
Term	Definition
GO:0008565	protein transporter activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 152..172
IPR029705	VPS35 endosomal protein sorting factor-like	PANTHER	PTHR13673	ESOPHAGEAL CANCER ASSOCIATED PROTEIN	coord: 4..874

Main menu

VPS35 endosomal protein sorting factor-like

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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