arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like

Overview


Name	arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like
Smed ID	SMED30032591
Length (bp)	3812

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like (SMED30032591) t-SNE clustered cells

Violin plots show distribution of expression levels for arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like (SMED30032591) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like (SMED30032591) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30032591

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30032591	SMESG000006535.1	PL05006A2E01	ncbi_smed_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30032591	SMESG000006535.1	PL030017B10A08	ncbi_smed_ests	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30032591	SMESG000006535.1	Contig49093	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30032591	SMESG000006535.1	Contig49093	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30032591	SMESG000006535.1	dd_Smed_v4_4332_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:HGNC:16924])

HSP 1 Score: 147.132 bits (370), Expect = 8.937e-35
Identity = 108/363 (29.75%), Postives = 174/363 (47.93%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLEN-----VKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQP-------EIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            KGI  + +++       NKF++ T  ++F F+    E    WI+ +   +  +    +S      +A+V+ E      ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T E+     +W   +    Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N   ++        E    FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  524 KGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQS------QAVVTPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAV----QQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 866

HSP 2 Score: 96.6709 bits (239), Expect = 2.363e-19
Identity = 88/364 (24.18%), Postives = 164/364 (45.05%), Query Frame = 3

Query: 1935 ADQSNNLRDFKNAIGQNLSPNFVPSFS---YACIGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDS----NCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            A+ S   R +  AI ++  P F  + +   Y  IG +        + W+   F +D  S+    ++ E +     D   + +++EL  S    N E +    +        I     H + D    H  + KA        D  +L +Q L++N+VP+ V+  I  +  +G   + +++K G       + +    D  S+ L        DV + LK F   ++D LLTK  Y  WI+A+D +D +++ + +   I  LP +N  TL  +I  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD    +   LL ++Y+
Sbjct:  985 AETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQG----DRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHG---HTKLDFTVWHTAIEKA-----AGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1334

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097])

HSP 1 Score: 127.872 bits (320), Expect = 6.984e-29
Identity = 94/354 (26.55%), Postives = 161/354 (45.48%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLL----KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM 1475
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +               ++ L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  +I  N +NR CA+C S+  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN+FW      GE       P     FI+ KY    F  RK     +Y D   L + L   V   N+++ M
Sbjct:  306 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF--RKP--HPQYPDHSQLLQALCAAVARPNLLKNM 633

HSP 2 Score: 85.8853 bits (211), Expect = 4.223e-16
Identity = 51/189 (26.98%), Postives = 94/189 (49.74%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL 2903
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +K++I  LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  +++
Sbjct:  909 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQV 1095

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097])

HSP 1 Score: 127.102 bits (318), Expect = 1.138e-28
Identity = 96/362 (26.52%), Postives = 166/362 (45.86%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLL----KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF---DGEQPEID----YRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM-QLFHIGA 1496
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +               ++ L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  +I  N +NR CA+C S+  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN+FW       +G  P+        FI+ KY    F  RK     +Y D   L + L   V   N+++ M QL  + A
Sbjct:  228 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF--RKP--HPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEA 563

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097])

HSP 1 Score: 127.102 bits (318), Expect = 1.138e-28
Identity = 96/362 (26.52%), Postives = 166/362 (45.86%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLL----KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF---DGEQPEID----YRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM-QLFHIGA 1496
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +               ++ L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  +I  N +NR CA+C S+  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN+FW       +G  P+        FI+ KY    F  RK     +Y D   L + L   V   N+++ M QL  + A
Sbjct:  228 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF--RKP--HPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEA 563

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097])

HSP 1 Score: 125.946 bits (315), Expect = 2.031e-28
Identity = 96/352 (27.27%), Postives = 164/352 (46.59%), Query Frame = 3

Query:  576 SNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLK----ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM-QLFHI----GADMNYVSEPSG-----LNSLETAGKYHQML 1568
            S+KD  NKF++ T  + F F+  S      W + +   + +++ +         +     ++ L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  +I  N +NR CA+C S+  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN+FW      GE       P     FI+ KY    F  RK     +Y D   L + L   V   N+++ M QL  +    G +  +   P G     L S  + G Y++++
Sbjct:    4 SSKD--NKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF--RKP--HPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVV 336

HSP 2 Score: 86.6557 bits (213), Expect = 2.449e-16
Identity = 51/189 (26.98%), Postives = 94/189 (49.74%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL 2903
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +K++I  LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  +++
Sbjct:  571 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQV 757

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: F23H11.4 (pep chromosome:WBcel235:III:902151:907539:-1 gene:WBGene00017760.1 transcript:F23H11.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F23H11.4)

HSP 1 Score: 94.3597 bits (233), Expect = 3.141e-19
Identity = 80/284 (28.17%), Postives = 139/284 (48.94%), Query Frame = 3

Query: 2124 GRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLA--SICLISSVIY-HLRGDTKESH-EELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDP---YDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLI---SGSDQMFNAK---NLQILPYLIRNYQDLFDVT-QEELEMEKLYNKER 2933
            G E + +DLRKV  + E  D +    CP   +     SI L    +Y   R D+  SH  E ++A L+    R +T L N  LT +N+P+ V K IR +  +G + EG++R+ G V EA+ I  +L  DP  Y   + +    Y VA  L+ FFRKL+ PL       +         S++    + ++IN   +++  TL+ LI  L N+ ++    + + +NL+  F   L    +  +++F+      + +L +L   Y  +F ++ +EEL  + + + E+
Sbjct:  504 GDELVEVDLRKVMTMRERIDKS--EFCPNARHKRGPFSITLHGVTLYIDSRDDSTTSHWYEAIEALLK----RPATRLENLRLTGDNIPVIVDKCIRFVSAYGMKCEGIYRRNGKVTEAKTILTKLTEDPVGYYPVHENDETVYAVADVLRQFFRKLDAPLFPSSSQADLFDLATESQSDELCARYAQLINTFELVHRSTLKKLIGHLKNVSEHAQENRASVENLAKVFAASLFLTDAMDEKVFSESYNHQINVLIHLTTGYDVVFQISIEEELSRQMVNDAEK 781

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14])

HSP 1 Score: 80.1073 bits (196), Expect = 5.875e-15
Identity = 57/195 (29.23%), Postives = 93/195 (47.69%), Query Frame = 3

Query:  933 RYKLTFESINLCNEWFHQITIIIQKAISATCSRNA---------RPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFW-LANFDGEQ---PEIDY----RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENII 1466
            R++    S+   +EW   I   I+K++    + NA         RP    +  I  N     CA+C +   EWAS+NL I +C +CSG+HR +G +ISK++G+  D+   E+   + + Q IGN+ AN+ W     +GE+   PE       RFI+ KY +K F              + +  +LI  V   +++
Sbjct:  338 RWEFCAGSLEERDEWIQAIGGEIEKSLGKEVA-NAKTNNRAVANRPDIAALRSIPGNGR---CADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEH---LAVMQAIGNDKANEMWEFGLLNGERKPTPESSREEKERFIDRKYVQKAF-------LKPIASGEPVTSQLISAVLARDVM 518

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14])

HSP 1 Score: 80.1073 bits (196), Expect = 7.321e-15
Identity = 54/164 (32.93%), Postives = 84/164 (51.22%), Query Frame = 3

Query:  933 RYKLTFESINLCNEWFHQITIIIQKAISATCSRNA---------RPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFW-LANFDGEQ---PEIDY----RFINDKYSRKRF 1373
            R++    S+   +EW   I   I+K++    + NA         RP    +  I  N     CA+C +   EWAS+NL I +C +CSG+HR +G +ISK++G+  D+   E+   + + Q IGN+ AN+ W     +GE+   PE       RFI+ KY +K F
Sbjct:  414 RWEFCAGSLEERDEWIQAIGGEIEKSLGKEVA-NAKTNNRAVANRPDIAALRSIPGNGR---CADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEH---LAVMQAIGNDKANEMWEFGLLNGERKPTPESSREEKERFIDRKYVQKAF 570

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14])

HSP 1 Score: 80.1073 bits (196), Expect = 7.759e-15
Identity = 54/164 (32.93%), Postives = 84/164 (51.22%), Query Frame = 3

Query:  933 RYKLTFESINLCNEWFHQITIIIQKAISATCSRNA---------RPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFW-LANFDGEQ---PEIDY----RFINDKYSRKRF 1373
            R++    S+   +EW   I   I+K++    + NA         RP    +  I  N     CA+C +   EWAS+NL I +C +CSG+HR +G +ISK++G+  D+   E+   + + Q IGN+ AN+ W     +GE+   PE       RFI+ KY +K F
Sbjct:  545 RWEFCAGSLEERDEWIQAIGGEIEKSLGKEVA-NAKTNNRAVANRPDIAALRSIPGNGR---CADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEH---LAVMQAIGNDKANEMWEFGLLNGERKPTPESSREEKERFIDRKYVQKAF 701

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14])

HSP 1 Score: 80.1073 bits (196), Expect = 8.058e-15
Identity = 54/164 (32.93%), Postives = 84/164 (51.22%), Query Frame = 3

Query:  933 RYKLTFESINLCNEWFHQITIIIQKAISATCSRNA---------RPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFW-LANFDGEQ---PEIDY----RFINDKYSRKRF 1373
            R++    S+   +EW   I   I+K++    + NA         RP    +  I  N     CA+C +   EWAS+NL I +C +CSG+HR +G +ISK++G+  D+   E+   + + Q IGN+ AN+ W     +GE+   PE       RFI+ KY +K F
Sbjct:  575 RWEFCAGSLEERDEWIQAIGGEIEKSLGKEVA-NAKTNNRAVANRPDIAALRSIPGNGR---CADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEH---LAVMQAIGNDKANEMWEFGLLNGERKPTPESSREEKERFIDRKYVQKAF 731

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: RhoGAP15B (gene:FBgn0030808 transcript:FBtr0110990)

HSP 1 Score: 80.1073 bits (196), Expect = 1.107e-14
Identity = 57/196 (29.08%), Postives = 109/196 (55.61%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSD--PYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFN-TCLISGSDQM-FNAKNLQILPYLIRNYQDLFDVTQEELEMEK 2915
            SL +Q LT+ +VP+ V K I  + +HG+  EG++RK GS     ++     +D  +  +T ++   +DVA+ LK F R L + LL KL  ++++   ++  + +K   ++E++ +L  I  +TLR ++  LV I       +M+  NL+  +  T L   SD++ ++ K   +L  L+  Y++LF  + +E++ E+
Sbjct: 1056 SLGDQQLTRYDVPVIVDKCINFVYIHGSMSEGIYRKSGSENSMHKLMSAFRADAFNVEITRNEYNEHDVANVLKRFMRDLPERLLGKL-TDSFVFVTELAVASEKIPIYRELLARLSAIERETLRRIVGHLVFISSQQAKNKMSVQNLTMIWGPTLLAKKSDELIYSQKEADVLSDLVVLYKNLFPCSADEIKREQ 1250

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: RhoGAP15B (gene:FBgn0030808 transcript:FBtr0290096)

HSP 1 Score: 80.1073 bits (196), Expect = 1.116e-14
Identity = 57/196 (29.08%), Postives = 109/196 (55.61%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSD--PYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFN-TCLISGSDQM-FNAKNLQILPYLIRNYQDLFDVTQEELEMEK 2915
            SL +Q LT+ +VP+ V K I  + +HG+  EG++RK GS     ++     +D  +  +T ++   +DVA+ LK F R L + LL KL  ++++   ++  + +K   ++E++ +L  I  +TLR ++  LV I       +M+  NL+  +  T L   SD++ ++ K   +L  L+  Y++LF  + +E++ E+
Sbjct: 1098 SLGDQQLTRYDVPVIVDKCINFVYIHGSMSEGIYRKSGSENSMHKLMSAFRADAFNVEITRNEYNEHDVANVLKRFMRDLPERLLGKL-TDSFVFVTELAVASEKIPIYRELLARLSAIERETLRRIVGHLVFISSQQAKNKMSVQNLTMIWGPTLLAKKSDELIYSQKEADVLSDLVVLYKNLFPCSADEIKREQ 1292

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenB1A (gene:FBgn0039056 transcript:FBtr0084369)

HSP 1 Score: 77.411 bits (189), Expect = 4.621e-14
Identity = 53/176 (30.11%), Postives = 86/176 (48.86%), Query Frame = 3

Query:  915 LITSYRRYKLTFESINLCNEWF----HQITIIIQ-------KAISATCSRNARPGEDIMH--EINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD--------GEQPEIDYR--FINDKYSRKRF 1373
            +I+  + + L  +S ++ + W     H I   IQ       +  S     N+ P +  +H  E  K   N +C +C+S +  WAS+NL ITLC +CSG+HR +G + SK++ +  D   WE+ N +++   +GN   N+ + A            EQ EI  R  +I  KY  +RF
Sbjct:   94 VISPTKSHILQADSADMLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLD--AWESEN-VKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRF 266

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenB1A (gene:FBgn0039056 transcript:FBtr0084368)

HSP 1 Score: 77.0258 bits (188), Expect = 8.356e-14
Identity = 54/185 (29.19%), Postives = 89/185 (48.11%), Query Frame = 3

Query:  888 DGNDSNSLSLITSYRRYKLTFESINLCNEWF----HQITIIIQ-------KAISATCSRNARPGEDIMH--EINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD--------GEQPEIDYR--FINDKYSRKRF 1373
            +G+      +I+  + + L  +S ++ + W     H I   IQ       +  S     N+ P +  +H  E  K   N +C +C+S +  WAS+NL ITLC +CSG+HR +G + SK++ +  D   WE+ N +++   +GN   N+ + A            EQ EI  R  +I  KY  +RF
Sbjct:  315 EGDRRFCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPAKRRIHWEEFLKIPGNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLD--AWESEN-VKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRF 496

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenG1A (gene:FBgn0028509 transcript:FBtr0080548)

HSP 1 Score: 69.707 bits (169), Expect = 1.514e-11
Identity = 37/105 (35.24%), Postives = 59/105 (56.19%), Query Frame = 3

Query: 1080 SNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGE-QP------EIDYRFINDKYSRKRF 1373
             N FC +C + + EWAS+NL + +C +CSG+HR +G +ISK++ +  D+  W + +L  +   IGN+ AN  W +N     +P      E   R++  KY  K F
Sbjct:  481 GNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDD--WPSPHL-SVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEF 582

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: arap1a (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a [Source:ZFIN;Acc:ZDB-GENE-030131-6226])

HSP 1 Score: 149.828 bits (377), Expect = 5.491e-36
Identity = 106/395 (26.84%), Postives = 189/395 (47.85%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVS------LENVKGK-RIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN-YVSEPSGLNSLETAGKYHQMLQLTYLN 1586
            + R+  L S  L  F+  +   SK  + L S+  +  V  V         +F+L +  ++F F+  + +    W++ I K++ D++   E  N       VS      LE +  + +++T+  +  +  + + E++  G+ +  I +R + V RDG +  S +L T YR +    +S +    W   +T  + +++S          + +   + +  +NR CA+C S+  EWASVNL + LC KC+G HR +G NISK++ +  DE  W + +LIR+F ++GN  ANKFW AN    +        E   + I DKY   ++ +  +     +   +ALN  L   +++ +++ T+ L + GAD   Y   P     L  A +Y Q +Q   L 
Sbjct:   74 QRRWVQLDSEYLRYFQSIKEVYSKRMVSLGSVFKVVSVGDV---------RFELHSQSRTFLFRAENTQERDDWVSCIEKILSDRKHSLEPRNLFFKNGSVSVSFEGYLEMLSPRTKVYTLINRDKLFLFKSHEEYFQGMGITDIDMRMANV-RDGENKRSFTLTTPYRAFSFMVDSESEKQRWCESLTECVSRSLSC---------DGVCESVWRVQANRICADCSSSMPEWASVNLCVLLCEKCAGAHRNLGQNISKVRSLKLDERVWTD-DLIRVFLMLGNGKANKFWGANIPPSERLSASANSEQRLKHITDKYKNGKYRKYHKL----FGQQEALNNALCLAMQSADLLETLTLLNCGADAACYTRIPEFPTPLSLAKRYSQTVQAELLT 444

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1])

HSP 1 Score: 130.568 bits (327), Expect = 6.577e-30
Identity = 90/341 (26.39%), Postives = 167/341 (48.97%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIG-----KLIYDKQQIDESDNSHLLK-ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSG 1526
            KG+  + ++  +     NKF++ T  ++F F+  +     KW + +      +L++ + +      SH  K   + L+  K K I+T      I  Y +++ FK GI +  I+ R + + RDG    S  LIT Y+ +  T E+     +W       +Q++I+ T S       ++  +I  N SN+ CA+CK+ + +WAS+NL + +C  C+G HR +G  +SK+Q +  D S W N  ++++F ++GN+ AN+FW A     +       PE    FI+ KY   R+     +    +   + L + L   V  +N+++T+      A+   +++ +G
Sbjct:  477 KGVIPLAAIQMARLAKDNKFEIVTSHRTFVFRADNDVQRSKWCSTLQERVKEQLVFGRPRF--GPGSHCQKSGFLELKGTKSK-IYTAIIMEQIWLYKSEQCFKNGIGITVIEARGATI-RDGK-GKSFDLITPYKTFSFTAETDREKRDWME----ALQESIAETLS-----DYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRGLGTMVSKVQSLKLDTSVWSN-EIVQLFIMLGNDRANEFWAARLPVSEELDCDATPEQRREFISHKYKEGRYRHPHPS----FSSQEELLKALCTAVTEQNLLKTVTQIFAEAEAARLADANG 798

HSP 2 Score: 89.3521 bits (220), Expect = 2.489e-17
Identity = 64/215 (29.77%), Postives = 104/215 (48.37%), Query Frame = 3

Query: 2259 HLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE 2897
            HL+G T  +   L  A +Q        +L +Q L++N++P+ V   I  +  +G   EG++RK G+    + + ++   D  +  L   D +  DV   LK FFR+++DP+     +  W  A  I    ++ + +KE+I  LP +N  TL  LI  L  + K  D+ QM   NLS  F   L     +      ++I+  LI NY  +FDV +E
Sbjct: 1026 HLQG-TGRTDFSLWYADIQKAAGGKGNTLKDQQLSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMEEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPFWKEAAKIPLKTQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGK--GEHEVKIIEDLIDNYLYIFDVDEE 1237

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: CR387919.1 (zmp:0000000660 [Source:NCBI gene;Acc:559690])

HSP 1 Score: 127.872 bits (320), Expect = 4.550e-29
Identity = 99/386 (25.65%), Postives = 175/386 (45.34%), Query Frame = 3

Query:  453 RYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDES--DNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRF------SERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            R+  L    L  +   +   SK  IPL ++K I  +           NKF++ T +++F F+     +   W+  +   +  +  +      N+      V L  +KG R++             D+DF  G+A+  + L ++ VK+   +   L + T ++ +  T ES +  +EW   I  + +  +   C+       +++ ++  N SNR CA+C++ + EWAS+NL + +C  C+G HR +GP ISK++ +  D S W N  LI +F  +GN N+N  W+AN     PE +    +    R  F        + + + +     + LN+ L   V   ++++TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  437 RWVKLEGGNLTYYNSEKEMYSKGLIPLSAVKQIRALGE---------NKFEVVTTLRTFVFRAEKEGDRQDWLEVLQAAVSSQSSVSHQPRKNNTNKSGYVELRGLKG-RVYLSLMGTCFRLCKTDQDFNAGLAIAVVDLTAACVKQ--FERKGLEITTPFKSFCFTVESEHERDEW---IEAVQESIVETLCNY------EVLEKVWFNKSNRKCADCQAPEPEWASINLCVVICKNCAGQHRFLGPGISKVRSMKLDSSIWTN-ELIELFLEVGNKNSNSLWVANLP---PEDELCKQSSTEQRASFIRRKYKKRKYKKVLNGLNTQEELNKALCAAVVLPDVLQTMALVFSGADVMCATGDPELSTPYLLAQKAGQRLQMEFL 797

HSP 2 Score: 92.0485 bits (227), Expect = 4.316e-18
Identity = 61/198 (30.81%), Postives = 97/198 (48.99%), Query Frame = 3

Query: 2331 DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-EMEK 2915
            D  +LSNQ + +N+VP+ V   I  +  +G   EG+++K G       +  +   D     L   +    DV   LK F    ED LL K  Y  WI+A+D +D + + + +   I  LP +N  TL  L+  L  I + + + QM+   L+  F++CL     +   A+  Q++  LI NY  LF V  E++ +MEK
Sbjct: 1042 DGMALSNQQMNKNDVPIIVDSCIAFVTQYGLCYEGIYQKKGDPGRVAHLIQEFTKDARVVKLRVQEQRLEDVTDTLKSFLSHSEDALLAKELYPFWISALDEQDEKVRVQKYSSYIQSLPKVNRSTLGALLQHLYRIQRCSHINQMSSQRLACVFSSCLF--QTEGHTAQETQVVEDLINNYIQLFSVNDEQVRQMEK 1237

[Close]

Query:  453 RYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDES--DNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRF------SERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            R+  L    L  +   +   SK  IPL ++K I  +           NKF++ T +++F F+     +   W+  +   +  +  +      N+      V L  +KG R++             D+DF  G+A+  + L ++ VK+   +   L + T ++ +  T ES +  +EW   I  + +  +   C+       +++ ++  N SNR CA+C++ + EWAS+NL + +C  C+G HR +GP ISK++ +  D S W N  LI +F  +GN N+N  W+AN     PE +    +    R  F        + + + +     + LN+ L   V   ++++TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  437 RWVKLEGGNLTYYNSEKEMYSKGLIPLSAVKQIRALGE---------NKFEVVTTLRTFVFRAEKEGDRQDWLEVLQAAVSSQSSVSHQPRKNNTNKSGYVELRGLKG-RVYLSLMGTCFRLCKTDQDFNAGLAIAVVDLTAACVKQ--FERKGLEITTPFKSFCFTVESEHERDEW---IEAVQESIVETLCNY------EVLEKVWFNKSNRKCADCQAPEPEWASINLCVVICKNCAGQHRFLGPGISKVRSMKLDSSIWTN-ELIELFLEVGNKNSNSLWVANLP---PEDELCKQSSTEQRASFIRRKYKKRKYKKVLNGLNTQEELNKALCAAVVLPDVLQTMALVFSGADVMCATGDPELSTPYLLAQKAGQRLQMEFL 797

HSP 2 Score: 92.0485 bits (227), Expect = 4.316e-18
Identity = 61/198 (30.81%), Postives = 97/198 (48.99%), Query Frame = 3

Query: 2331 DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-EMEK 2915
            D  +LSNQ + +N+VP+ V   I  +  +G   EG+++K G       +  +   D     L   +    DV   LK F    ED LL K  Y  WI+A+D +D + + + +   I  LP +N  TL  L+  L  I + + + QM+   L+  F++CL     +   A+  Q++  LI NY  LF V  E++ +MEK
Sbjct: 1042 DGMALSNQQMNKNDVPIIVDSCIAFVTQYGLCYEGIYQKKGDPGRVAHLIQEFTKDARVVKLRVQEQRLEDVTDTLKSFLSHSEDALLAKELYPFWISALDEQDEKVRVQKYSSYIQSLPKVNRSTLGALLQHLYRIQRCSHINQMSSQRLACVFSSCLF--QTEGHTAQETQVVEDLINNYIQLFSVNDEQVRQMEK 1237

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: FO704810.1 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like [Source:NCBI gene;Acc:100005008])

HSP 1 Score: 112.464 bits (280), Expect = 1.763e-24
Identity = 88/350 (25.14%), Postives = 160/350 (45.71%), Query Frame = 3

Query:  558 VDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN-YVSEPSGLNSLETAGKYHQMLQLTYL 1583
            V SV   +K +  +F +    K F+F   +      W++ +    YD +   E+  +      +S+++ + K++++     ++  Y + EDF  G+ M  + +  + VK  G      SLIT YR +  + +S    + W   +  +I+ A+S +         ++   +  +  N+ CA+C + + EWASVNL + +C  C+G HR MG + SK++G+  D+  W    LI++F + GN  AN  W  N    +       P+    FI  KY +  +  RK       +  + L++ L E V    +  T+ L   GA ++   S+P   +++  A    Q LQ   L
Sbjct:  240 VASVTNISKQEHGRFSIHLQKKHFEFMAHNAAVQDGWLHSL----YDSRG-REAIAAPKKHGPLSMKD-RRKKVYSAICGHSLWIYSSKEDFNLGLGMMCVSMNIASVKSTGR--YGFSLITPYRTFNFSADSSKEASAWLESLNDVIRNALSYS---------EVALRLWSSPCNKVCADCGAANPEWASVNLLVVICEACAGAHRSMGSSRSKVRGLKLDDKVWTE-PLIQLFVLHGNKTANNVWGHNIPPTEQISPLASPDQRAEFILAKYHKGLY--RKAHPLAASQ--KLLDQRLREVVCGPAVEETVSLLCSGAKVSCSSSDPELKSAIAVAESAGQALQTELL 567

HSP 2 Score: 78.9518 bits (193), Expect = 2.992e-14
Identity = 49/174 (28.16%), Postives = 85/174 (48.85%), Query Frame = 3

Query: 2367 NNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSD--PYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLF 2882
             +VP  V + I H+ LHG  +EGL+R+ G   +  ++ D L   P   VL   +    DV+ ALK   R+ E  L+ + +  +W  A  +   + + + ++E++ +LP  N  TL  L   L N+ K++   +M   NL+  F   +I   +   N   +Q+   LI N+  +F
Sbjct:  775 GSVPTSVHRCISHITLHGLMVEGLYRRCGIAPQISKLVDTLRVSPKEAVLQTDELSVLDVSGALKQILRQSE--LIPQTHRPHWQNAAALPGEKVRLQTYRELLKQLPPDNIATLSALCAHLNNVQKHSQTNRMTAHNLAVIF--VVIFFQELAMNINMVQMTRELILNHTHIF 944

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: ccn4 (cellular communication network factor 4 [Source:Xenbase;Acc:XB-GENE-484776])

HSP 1 Score: 141.739 bits (356), Expect = 2.935e-33
Identity = 193/811 (23.80%), Postives = 344/811 (42.42%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSGLNSLET----AGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYW-------LSINQNPKEFRIILIWKSCIQ--ILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQETDYSTKPADYXXXX----XXXXXXXXADQSNNLRDFKNAIGQNLSP---NFVPSFSYACIGWVILSTVSE--DWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVL--TNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE 2897
            KG   + ++   NK   +KF++ T  ++F F+    E+   WI+ +  L   K +  E  +  + +    LE +KG   +I+ +     + +  + +D   GIA+  + L    VK    D  S  L T +R + LT ES     EW  +I    Q++I+ T +       ++  +I  N SNR CA+C++   +WAS++L + +C  C+ L+R M                     L R                            FI  KY   RF   K+  F  +   + LN+ L + V  + I++TM L   GAD      P+G     T    A    Q LQ+ +L+     ++ D+++   ++      N     Y G  +       ++IN+  KE   +  W   I+   L     E   +    I L       SE ISLVI    +D+S+                + +  A+   + R++  AI +N +P    ++    +  +G++     S    WK   F ++   +    + + G      D  ++ K++EL +S+  +     +  L        +  H   D    H  + KA        D  +L +Q L++NN+P+ V+  I  +  +G   + L+ K G+  +   + ++   D  S  L        DV   LK FF +++D LLTK  Y  WI+A+DIR+ +++ + +K +I+ +P +N  TL  LI  L  I K  D+  ++   L+ +F++CL   + +  N K + +L  LI NY ++F+V+ +
Sbjct:  414 KGKISLPAITKVNKMGESKFEVVTVQRTFVFRAEKEEDRDDWIDTL--LRTSKSEPYEFPDLCVTEKNGYLE-LKGYKNKIYAVINGSKLWFSKSKQDASAGIAITDLTLTMVSVKII--DRKSFELTTPFRHFCLTAESEREKQEWTEEI----QQSIAETLA-----DYEVAEKIWFNESNRSCADCRAPSPDWASISLGVVICKNCAALNRSM---------------------LQRRL--------------------------FITQKYKEGRF---KKIYFPGFTQEE-LNQALCDAVTKDEILQTMILVFSGADTMC---PTGDKVYNTPYLLAKMSGQRLQMEFLHHN---RLSDFKAPSLNA------NGASLFYCGFLYKASPSTKMTINRKSKE--EMKQWWCTIENNFLKYYENETAPVADGVIDL-------SEIISLVI--HPSDFSSNGMAAFTFEIYFLSERMFLFGAENVESRREWSRAIAKNFTPAVEGYLLELDFNVLGYLNYKNSSSLSQWKKGWFALEKARLHYCNKDDCGN----ADTIQLKKLQELTNSSTLNGEKGNILLLVENGRTFYIHGHTMLDFTVWHSAIEKA-----AGTDGNALQDQQLSKNNIPIIVNSCIAFVTQYGLGSKSLYLKNGNPLQVRELLEEFKKDARSIKLKVGKHQLEDVTDVLKYFFYEIDDALLTKELYPYWISALDIRNEQERVKKYKTVISTVPALNKATLAALIEHLFRIQKCFDINHLDTQTLAKAFSSCLFQTNGE--NEKEVAVLEDLITNYVNIFNVSMD 1125

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969])

HSP 1 Score: 107.071 bits (266), Expect = 1.336e-22
Identity = 71/262 (27.10%), Postives = 129/262 (49.24%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHI------GKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF 1310
            KG+  + S+  +     NKF++ T  ++F F+  +     +W   I       ++++ + ++  S +       + L+  K K IF +     +  + N++ FK GI M  I +    + RD  + N   L+T  + +  T ES     EW   +   I +++S           ++  +I  N SN+ CA+C+      AS+NL + +C +C+G+HR +G NISK+Q +  D S W N  ++++F I+GN+ AN+FW A  
Sbjct:  280 KGVIPLSSIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMVFPRLRLGCSSSCQR-SGYLELKGYKSK-IFAVLTTDELWIHKNEQLFKMGIGMFVIGMHGCTI-RDVRNKN-FELVTMQKIFSFTAESEREKKEWMEALLECISESLS---------DYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSN-EIVQLFIILGNDKANRFWAAKL 521

HSP 2 Score: 99.3673 bits (246), Expect = 2.827e-20
Identity = 62/207 (29.95%), Postives = 103/207 (49.76%), Query Frame = 3

Query: 2310 LQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYN 2924
            +Q+        L  Q L++N++P+ V   I  L  +G + EG++RK G+    + + D+   D  +  L  SD +  DV   LK FFR+L+DP+ T   +  W  A D  +  K+ E + E+IN LP +N  TL  LI  L  + K  D+ QM   NL+  F   L     +      ++++  +I NY  +F++ +E++    L N
Sbjct:  788 IQAAACSSGNVLREQQLSRNDIPIIVDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAADNPEKSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTDGK--GEHEVKVMEDIIDNYASVFEIDEEQVTQMDLEN 992

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969])

HSP 1 Score: 107.071 bits (266), Expect = 1.424e-22
Identity = 71/262 (27.10%), Postives = 129/262 (49.24%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHI------GKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF 1310
            KG+  + S+  +     NKF++ T  ++F F+  +     +W   I       ++++ + ++  S +       + L+  K K IF +     +  + N++ FK GI M  I +    + RD  + N   L+T  + +  T ES     EW   +   I +++S           ++  +I  N SN+ CA+C+      AS+NL + +C +C+G+HR +G NISK+Q +  D S W N  ++++F I+GN+ AN+FW A  
Sbjct:  347 KGVIPLSSIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMVFPRLRLGCSSSCQR-SGYLELKGYKSK-IFAVLTTDELWIHKNEQLFKMGIGMFVIGMHGCTI-RDVRNKN-FELVTMQKIFSFTAESEREKKEWMEALLECISESLS---------DYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSN-EIVQLFIILGNDKANRFWAAKL 588

HSP 2 Score: 98.5969 bits (244), Expect = 5.615e-20
Identity = 84/337 (24.93%), Postives = 151/337 (44.81%), Query Frame = 3

Query: 1935 ADQSNNLRDFKNAIGQNLSP---NFVPSFSYACIGWVILSTV--SEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYN 2924
             D +  L+ + +AIG+  +P   + + +  +  +G +    +   + W    F +  C +     +  G +N   D   + +++EL  S  E+     M     I +      +L+G TK          +Q+        L  Q L++N++P+ V   I  L  +G + EG++RK G+    + + D+   D  +  L  SD +  DV   LK FFR+L+DP+ T   +  W  A    +  K+ E + E+IN LP +N  TL  LI  L  + K  D+ QM   NL+  F   L     +      ++++  +I NY  +F++ +E++    L N
Sbjct:  777 TDAAETLQTWTSAIGKWFTPVSCHCLVAHEFQRVGRMRYKAMLNPDHWMEGFFLLKKCHLF----ICPGDQNAAEDSVNLRQLQELSKSRSENTEKKDML----ILVEKGRTLYLQGVTKADFLAW-STDIQAAACSSGNVLREQQLSRNDIPIIVDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAA---EKSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTDGK--GEHEVKVMEDIIDNYASVFEIDEEQVTQMDLEN 1099

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969])

HSP 1 Score: 106.686 bits (265), Expect = 1.754e-22
Identity = 71/262 (27.10%), Postives = 129/262 (49.24%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHI------GKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF 1310
            KG+  + S+  +     NKF++ T  ++F F+  +     +W   I       ++++ + ++  S +       + L+  K K IF +     +  + N++ FK GI M  I +    + RD  + N   L+T  + +  T ES     EW   +   I +++S           ++  +I  N SN+ CA+C+      AS+NL + +C +C+G+HR +G NISK+Q +  D S W N  ++++F I+GN+ AN+FW A  
Sbjct:  299 KGVIPLSSIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMVFPRLRLGCSSSCQR-SGYLELKGYKSK-IFAVLTTDELWIHKNEQLFKMGIGMFVIGMHGCTI-RDVRNKN-FELVTMQKIFSFTAESEREKKEWMEALLECISESLS---------DYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSN-EIVQLFIILGNDKANRFWAAKL 540

HSP 2 Score: 102.449 bits (254), Expect = 3.224e-21
Identity = 101/429 (23.54%), Postives = 188/429 (43.82%), Query Frame = 3

Query: 1662 KQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQETDYSTKPADYXXXXXXXXXXXXADQSNNLRDFKNAIGQNLSP---NFVPSFSYACIGWVILSTV--SEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEEL-KDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYN 2924
            ++  Y+G +   +N   +  +I+ +  SC  IL   N+  CK  +R   LI+ K   +   +++++     Y  +    +      +     D +  L+ + +AIG+  +P   + + +  +  +G +    +   + W    F +  C +     +  G +N   D   + +++EL K  N E            I +      +L+G TK          +Q+        L  Q L++N++P+ V   I  L  +G + EG++RK G+    + + D+   D  +  L  SD +  DV   LK FFR+L+DP+ T   +  W  A D  +  K+ E + E+IN LP +N  TL  LI  L  + K  D+ QM   NL+  F   L     +      ++++  +I NY  +F++ +E++    L N
Sbjct:  564 REGKYRG-FHPQLNTQEEILKILTV--SCCTILGKCNRR-CKAFYRFTLLIKSKKAITMPANIMLICCFFCYRFRYMFEIYLVTEKVHQFGTDAAETLQTWTSAIGKWFTPVSCHCLVAHEFQRVGRMRYKAMLNPDHWMEGFFLLKKCHLF----ICPGDQNAAEDSVNLRQLQELSKSKNTEK-------KDMLILVEKGRTLYLQGVTKADFLAW-STDIQAAACSSGNVLREQQLSRNDIPIIVDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAADNPEKSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTDGK--GEHEVKVMEDIIDNYASVFEIDEEQVTQMDLEN 974

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969])

HSP 1 Score: 106.301 bits (264), Expect = 2.138e-22
Identity = 71/262 (27.10%), Postives = 129/262 (49.24%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHI------GKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF 1310
            KG+  + S+  +     NKF++ T  ++F F+  +     +W   I       ++++ + ++  S +       + L+  K K IF +     +  + N++ FK GI M  I +    + RD  + N   L+T  + +  T ES     EW   +   I +++S           ++  +I  N SN+ CA+C+      AS+NL + +C +C+G+HR +G NISK+Q +  D S W N  ++++F I+GN+ AN+FW A  
Sbjct:  328 KGVIPLSSIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMVFPRLRLGCSSSCQR-SGYLELKGYKSK-IFAVLTTDELWIHKNEQLFKMGIGMFVIGMHGCTI-RDVRNKN-FELVTMQKIFSFTAESEREKKEWMEALLECISESLS---------DYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSN-EIVQLFIILGNDKANRFWAAKL 569

HSP 2 Score: 99.7525 bits (247), Expect = 2.309e-20
Identity = 92/376 (24.47%), Postives = 165/376 (43.88%), Query Frame = 3

Query: 1821 KLNESEGISLVIVVQETDYSTKPADYXXXXXXXXXXXXADQSNNLRDFKNAIGQNLSP---NFVPSFSYACIGWVILSTV--SEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEEL-KDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYN 2924
            K++ SE + + +  Q  D    P+      +S       D +  L+ + +AIG+  +P   + + +  +  +G +    +   + W    F +  C +     +  G +N   D   + +++EL K  N E            I +      +L+G TK          +Q+        L  Q L++N++P+ V   I  L  +G + EG++RK G+    + + D+   D  +  L  SD +  DV   LK FFR+L+DP+ T   +  W  A D  +  K+ E + E+IN LP +N  TL  LI  L  + K  D+ QM   NL+  F   L     +      ++++  +I NY  +F++ +E++    L N
Sbjct:  680 KIDPSEVVCMGVTRQ--DVLCSPSPVERYCMSGFHQFGTDAAETLQTWTSAIGKWFTPVSCHCLVAHEFQRVGRMRYKAMLNPDHWMEGFFLLKKCHLF----ICPGDQNAAEDSVNLRQLQELSKSKNTEK-------KDMLILVEKGRTLYLQGVTKADFLAW-STDIQAAACSSGNVLREQQLSRNDIPIIVDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAADNPEKSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTDGK--GEHEVKVMEDIIDNYASVFEIDEEQVTQMDLEN 1039

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:MGI Symbol;Acc:MGI:2684416])

HSP 1 Score: 147.132 bits (370), Expect = 6.849e-35
Identity = 110/363 (30.30%), Postives = 174/363 (47.93%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLEN-----VKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD-GEQPEIDY------RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            KGI  + +++       NKF++ T  ++F F+    E    WI+ +   +       +      L+A V+ E      ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T +S     EW       +Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N    E+ ++D        FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  522 KGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLASQ------LQAAVAPEKCGYLELRGYKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTADSEREKQEWIE----AVQQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 864

HSP 2 Score: 93.5893 bits (231), Expect = 1.288e-18
Identity = 58/208 (27.88%), Postives = 105/208 (50.48%), Query Frame = 3

Query: 2331 DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKD 2948
            D  +L +Q L +N+VP+ V+  I  +  +G   + +++K G       + +    D  S  L        DV   LK F   ++D LLTK  Y  W++A+D +D +++   ++  I  LP +N  TL  LI  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD
Sbjct: 1112 DGNALQDQQLCKNDVPIIVNSCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMNAHNLAMVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKD 1317

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:MGI Symbol;Acc:MGI:2147274])

HSP 1 Score: 122.479 bits (306), Expect = 1.869e-27
Identity = 92/354 (25.99%), Postives = 162/354 (45.76%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSH----LLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM 1475
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +      H    L    + L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  ++  N +NR CA+C+++  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN FW      GE       P     FI+ KY    F  RK     ++ D   L + L   +   N+++ M
Sbjct:  301 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDLWCSTLQSCLKEQRLLGHPRPPHPPRPLRTGTLELRGHKAKVFAALIPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANCFWAGALPPGEGLHPDSAPGPRGEFISRKYKLGLF--RKP--HPRHPDHSQLLQALCAAMAGPNLLKNM 628

HSP 2 Score: 87.0409 bits (214), Expect = 1.212e-16
Identity = 52/188 (27.66%), Postives = 94/188 (50.00%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEE 2900
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +KE+I+ LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  ++
Sbjct:  905 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQ 1090

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:MGI Symbol;Acc:MGI:2147274])

HSP 1 Score: 122.479 bits (306), Expect = 2.080e-27
Identity = 92/354 (25.99%), Postives = 162/354 (45.76%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSH----LLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM 1475
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +      H    L    + L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  ++  N +NR CA+C+++  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN FW      GE       P     FI+ KY    F  RK     ++ D   L + L   +   N+++ M
Sbjct:  223 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDLWCSTLQSCLKEQRLLGHPRPPHPPRPLRTGTLELRGHKAKVFAALIPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANCFWAGALPPGEGLHPDSAPGPRGEFISRKYKLGLF--RKP--HPRHPDHSQLLQALCAAMAGPNLLKNM 550

HSP 2 Score: 86.6557 bits (213), Expect = 1.575e-16
Identity = 52/188 (27.66%), Postives = 94/188 (50.00%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEE 2900
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +KE+I+ LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  ++
Sbjct:  827 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQ 1012

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:MGI Symbol;Acc:MGI:1916960])

HSP 1 Score: 120.168 bits (300), Expect = 9.350e-27
Identity = 88/369 (23.85%), Postives = 158/369 (42.82%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVS----------LENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN-YVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDP 1646
             KF++ T  ++F F+  S     +W+  + + + + +      ++ +L    S          L   K K ++       +  Y N E+F  GI +  I +    VK    D  S  L T YR +  + +S     +W   +   I +A+S +         ++   I   A NRFCA+C +   +WAS+NL + +C +C+G HR +G  +SK++ +  D   W    LI++F  +GN   N FW AN    +       P      +  KY   ++  R   +F    + + L++ L   V T ++  T  L   GA ++ +  +P+    L  A +  Q LQ+ +L +    ++        DS+ P
Sbjct:  388 QKFEVITNNRTFAFRAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVRGSEQPDRAGSLELRGFKNK-LYVAVTGDKVQLYKNLEEFHLGIGITFIDMNVGNVKE--VDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS---------EVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKY-RRYHPLFG---NQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPAAPTPLALAEQAGQTLQMEFLRNNQSTEV-----PRLDSVKP 734

HSP 2 Score: 91.2781 bits (225), Expect = 6.075e-18
Identity = 62/194 (31.96%), Postives = 102/194 (52.58%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEK 2915
            +LS Q L  +++P+ V + + ++   G   EG++RK G   + +R+ D L  D  S  L   + +  DV+SALK F R L D L T+     W+ A +I D E+K   ++E++  LP +N  T++ LI  L  +   +D  QMN  NL+  F   L     Q + A   +++  LI +Y  +F V +EEL  ++
Sbjct:  961 TLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAG--KVVEDLINHYVVVFSVDEEELRKQR 1152

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:MGI Symbol;Acc:MGI:1916960])

HSP 1 Score: 120.168 bits (300), Expect = 9.966e-27
Identity = 88/369 (23.85%), Postives = 158/369 (42.82%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVS----------LENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN-YVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDP 1646
             KF++ T  ++F F+  S     +W+  + + + + +      ++ +L    S          L   K K ++       +  Y N E+F  GI +  I +    VK    D  S  L T YR +  + +S     +W   +   I +A+S +         ++   I   A NRFCA+C +   +WAS+NL + +C +C+G HR +G  +SK++ +  D   W    LI++F  +GN   N FW AN    +       P      +  KY   ++  R   +F    + + L++ L   V T ++  T  L   GA ++ +  +P+    L  A +  Q LQ+ +L +    ++        DS+ P
Sbjct:  388 QKFEVITNNRTFAFRAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVRGSEQPDRAGSLELRGFKNK-LYVAVTGDKVQLYKNLEEFHLGIGITFIDMNVGNVKE--VDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS---------EVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKY-RRYHPLFG---NQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPAAPTPLALAEQAGQTLQMEFLRNNQSTEV-----PRLDSVKP 734

HSP 2 Score: 91.6633 bits (226), Expect = 5.889e-18
Identity = 62/194 (31.96%), Postives = 102/194 (52.58%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEK 2915
            +LS Q L  +++P+ V + + ++   G   EG++RK G   + +R+ D L  D  S  L   + +  DV+SALK F R L D L T+     W+ A +I D E+K   ++E++  LP +N  T++ LI  L  +   +D  QMN  NL+  F   L     Q + A   +++  LI +Y  +F V +EEL  ++
Sbjct:  961 TLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAG--KVVEDLINHYVVVFSVDEEELRKQR 1152

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8WZ64|ARAP2_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARAP2 PE=1 SV=3)

HSP 1 Score: 147.132 bits (370), Expect = 4.292e-34
Identity = 108/363 (29.75%), Postives = 174/363 (47.93%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLEN-----VKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQP-------EIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            KGI  + +++       NKF++ T  ++F F+    E    WI+ +   +  +    +S      +A+V+ E      ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T E+     +W   +    Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N   ++        E    FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  524 KGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQS------QAVVTPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAV----QQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 866

HSP 2 Score: 96.6709 bits (239), Expect = 1.135e-18
Identity = 88/364 (24.18%), Postives = 164/364 (45.05%), Query Frame = 3

Query: 1935 ADQSNNLRDFKNAIGQNLSPNFVPSFS---YACIGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDS----NCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            A+ S   R +  AI ++  P F  + +   Y  IG +        + W+   F +D  S+    ++ E +     D   + +++EL  S    N E +    +        I     H + D    H  + KA        D  +L +Q L++N+VP+ V+  I  +  +G   + +++K G       + +    D  S+ L        DV + LK F   ++D LLTK  Y  WI+A+D +D +++ + +   I  LP +N  TL  +I  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD    +   LL ++Y+
Sbjct:  985 AETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQG----DRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHG---HTKLDFTVWHTAIEKA-----AGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1334

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8BZ05|ARAP2_MOUSE (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Arap2 PE=1 SV=2)

HSP 1 Score: 144.821 bits (364), Expect = 1.979e-33
Identity = 109/363 (30.03%), Postives = 173/363 (47.66%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLEN-----VKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD-GEQPEIDY------RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            KGI  + +++       NKF++ T  ++F F+    E    WI+ +   +       +      L+A V+ E      ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T +S     EW       +Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP   K++ +  D S W N  LI +F +IGN  AN FW  N    E+ ++D        FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  522 KGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLASQ------LQAAVAPEKCGYLELRGYKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTADSEREKQEWIE----AVQQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDCKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 864

HSP 2 Score: 93.9745 bits (232), Expect = 8.493e-18
Identity = 58/208 (27.88%), Postives = 105/208 (50.48%), Query Frame = 3

Query: 2331 DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKD 2948
            D  +L +Q L +N+VP+ V+  I  +  +G   + +++K G       + +    D  S  L        DV   LK F   ++D LLTK  Y  W++A+D +D +++   ++  I  LP +N  TL  LI  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD
Sbjct: 1112 DGNALQDQQLCKNDVPIIVNSCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMNAHNLAMVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKD 1317

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8WWN8|ARAP3_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ARAP3 PE=1 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 3.354e-28
Identity = 94/354 (26.55%), Postives = 161/354 (45.48%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLL----KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM 1475
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +               ++ L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  +I  N +NR CA+C S+  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN+FW      GE       P     FI+ KY    F  RK     +Y D   L + L   V   N+++ M
Sbjct:  306 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF--RKP--HPQYPDHSQLLQALCAAVARPNLLKNM 633

HSP 2 Score: 85.8853 bits (211), Expect = 2.028e-15
Identity = 51/189 (26.98%), Postives = 94/189 (49.74%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL 2903
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +K++I  LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  +++
Sbjct:  909 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQV 1095

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8R5G7|ARAP3_MOUSE (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 OS=Mus musculus OX=10090 GN=Arap3 PE=1 SV=3)

HSP 1 Score: 122.479 bits (306), Expect = 1.308e-26
Identity = 92/354 (25.99%), Postives = 162/354 (45.76%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSH----LLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGE------QPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTM 1475
            + R+       L+ F   +    K  IPL +++       +  S+KD  NKF++ T  + F F+  S      W + +   + +++ +      H    L    + L   K K    + P   +A Y +++ F  GI +  I+L+   V+     S S  L+T +R +  T ES      W       +Q+A++ T S       ++  ++  N +NR CA+C+++  +WA+VNL + +C +C+G HR +G  ISK+Q +  D S W N  ++++F ++GN+ AN FW      GE       P     FI+ KY    F  RK     ++ D   L + L   +   N+++ M
Sbjct:  301 QRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE-------MTRSSKD--NKFQVITGQRVFVFRTESEAQRDLWCSTLQSCLKEQRLLGHPRPPHPPRPLRTGTLELRGHKAKVFAALIPG-ELALYKSEQAFSLGIGICFIELQGCSVRE--TKSRSFDLLTPHRCFSFTAESGGARQSW----AAALQEAVTETLSDY-----EVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSN-EIVQLFIVLGNDRANCFWAGALPPGEGLHPDSAPGPRGEFISRKYKLGLF--RKP--HPRHPDHSQLLQALCAAMAGPNLLKNM 628

HSP 2 Score: 87.0409 bits (214), Expect = 8.475e-16
Identity = 52/188 (27.66%), Postives = 94/188 (50.00%), Query Frame = 3

Query: 2343 LSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEE 2900
            L  Q +++ ++P+ V   I  +  HG ++EG++RK G+   + R+  +   D  S  L   + +  DV   LK FFR+L+DP+ +      W  A ++    ++ E +KE+I+ LP +N +TL  LI  L  + K   + QM   NL+  F   +     +      +++L  LI  Y  +FD+  ++
Sbjct:  905 LQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTDGR--GEHEVRVLQELIDGYISVFDIDSDQ 1090

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q96P48|ARAP1_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3)

HSP 1 Score: 122.479 bits (306), Expect = 1.461e-26
Identity = 85/349 (24.36%), Postives = 152/349 (43.55%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLL----------KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN-YVSEPSGLNSLETAGKYHQMLQLTYLN 1586
             KF++ T  ++F F+  S     +W+  + + + +++      +++LL             + L   K K ++       +  Y N E++  GI +  I +    VK    D  S  L T YR +  + +S     +W   +   I +A+S +         ++   I   A NRFCA+C +   +WAS+NL + +C +C+G HR +G  +SK++ +  D   W    LI +F  +GN   N+FW AN    +       P      +  KY   ++  R   +F    + + L++ L   V T ++  T  L   GA +N +  +P     L  A +  Q LQ+ +L 
Sbjct:  386 QKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNK-LYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKE--VDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS---------EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTE-TLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKY-RRYHPLFG---NQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLR 717

HSP 2 Score: 91.2781 bits (225), Expect = 4.836e-17
Identity = 61/194 (31.44%), Postives = 103/194 (53.09%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEK 2915
            +LS Q L  +++P+ V + + ++   G   EG++RK G   + +R+ + L  D  S  L   + +  DV+SALK F R L D L T+     W+ A +I D E+K   ++E++ +LP +N  T++ LI  L  +   +D  QMN  NL+  F   L     Q + A   +++  LI +Y  +F V +EEL  ++
Sbjct:  959 TLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAG--RVVEDLINHYVVVFSVDEEELRKQR 1150

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A3L8SUZ2 (Uncharacterized protein (Fragment) OS=Chloebia gouldiae OX=44316 GN=DV515_00002877 PE=4 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 5.848e-55
Identity = 222/860 (25.81%), Postives = 381/860 (44.30%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIG---KLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGEQPEID------YRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDP-------DNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIR-EKLNESEGI-----SLVIVVQETDYSTKPADYXXXXXXXXXXXX----ADQSNNLRDFKNAIGQNLSPNFVPS-FSYAC--IGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVR-------DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            KGI  + ++        NKF++ T  ++F F+    E    W+N +    KL+ D      S  +      + L+  K K IF +    T+    N++DFK G  +  I +  + VK+ D     S  +IT Y+ +  T ES     +W   +    Q++I+ T S       ++  +I  N SNR CA+CK+   +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F IIGN  AN FW  N    E+  ID        FI  KY   +F   ++T F  YK  + LN+ L   V  ++++ T+ L   GAD M    +P        A K  Q LQ+ +L          + +   D  + DP       +++  + +  ++   ++ N  +       K      DC NK  C +    +     +K     G+      + +VV ++D+     D     + ++        A+ +++ R + +AI ++  P    S     C  IG +        + W+   F I+  S+    E+ +  E+  I LR   +++EL  S+        M N   I ++  V    +G T   H      F+  WY         D  +L +Q L++N+VP+ V+  I  +  +G   + ++ K G       + +    D  S  L        DV   LK F  +++D LLTK  Y  WI+A+D ++ +++   ++  I  LP +N  TL  LI  L  + K +++ QMNP NL+  F++CL     Q   ++ + ++  LI+NY  LF + +++++   + N    K KD    +   LL ++Y+
Sbjct:  207 KGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNTMLNALKLLSDNNSQSRSSVTPEKSGYLELKGYKTK-IFILLQGSTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKQSFEIITPYKSFSFTAESEKEKQDWIEAL----QQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPGPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSN-ELIELFIIIGNKRANSFWAGNLPPDEELHIDDPAEKRIAFITQKYKEGKF---RKTPF-HYKTKEQLNKALCAAVVKQDVLETLMLLFSGADAMCATGDPVYSTPYLLAKKAGQRLQMEFL----------YHNKFSDFPNYDPCFESGFSEDSSHSTFLCEFLYKVSSNAAKLPTEKKLKE-----DC-NKRWCTLESGFLSYYENDKTTTPNGMIDVNEVICLVVHKSDFFINRGDIFTFEMYLLSERVFLFGAETAHSQRKWTSAIAKHFVPPVAESLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLYFCLEMEDAEED-SIYLR---RLQELTTSSV-------MQNGERIDVLLLV---EKGRTLYIHGHTKLDFM-VWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKQIYLKNGDSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDALLTKELYPFWISALDTQNEKERVRKYRAFIRSLPPVNRATLAALIEHLYRVQKCSEINQMNPQNLAVVFSSCLFQTKGQ--TSEEVNVIEDLIKNYVQLFHINEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1018

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A093QCG1 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Fragment) OS=Manacus vitellinus OX=328815 GN=N305_07220 PE=4 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 1.885e-54
Identity = 218/853 (25.56%), Postives = 375/853 (43.96%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIG---KLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGEQPEIDY------RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIR-EKLNESEGI-----SLVIVVQETDYSTKPADYXX----XXXXXXXXXXADQSNNLRDFKNAIGQNLSPNFVPSF---SYACIGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVR-------DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            KGI  + ++        NKF++ T  ++F F+    E    W+N +    KL+ D      +  +      + L+  K K IF +    T+    N++DFK G  +  I +  + VK+ D     S  +IT Y+ +  T ES     +W       +Q++I+ T S       ++  +I  N SNR CA+CK+   +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N   GE+  +D        FI  KY   +F  RK      YK  + LN+ L   V  ++++ T+ L   GAD M    +P        A K  Q LQ+ +L         ++ +        D   +  + +  ++   ++ N  +   +L  K   +  DC NK  C +    +     +K     G+      + +VVQ+TD+ +   D            +    A+ + + R +  AI ++  P    S     +  IG +        + W+   F I+  S+    E+    E+  I LR   +++EL  S+        M N   I ++  V    +G T   H      F+  WY         D  +L +Q L++N+VP+ V+  I  +  +G   + ++ K G       + +    D  S  L        DV   LK F  +++D LLTK  Y  WI+A+D ++ +++   +   I+ LP +N  TL  LI  L  + K +++  MNP NL+  F++CL     Q   ++ + ++  LI+NY  +F + +++++   + N    K KD    +   LL ++Y+
Sbjct:  496 KGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNTMLNALKLLSDNNSQSRTSVAPEKSGYLELKGYKAK-IFIVLQGSTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKQSFEIITPYKSFSFTAESEREKQDWIE----ALQQSIAETLS-----DYEVAEKIWFNESNRSCADCKTPSPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSN-ELIELFIVIGNKRANSFWAGNLPPGEELHMDAPAEKRIAFITQKYKEGKF--RKAPFL--YKTKEQLNKALCAAVVKQDVLETLMLLFSGADAMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTCFESGFSED---SSHSTFLCEFLYKVSSNAAK---LLTEKKLKE--DC-NKRWCTLESGFLSYYENDKTTTPNGMIDINEVICLVVQKTDFFSNRGDIFTFEIYLMSERVFQFGAETAYSQRKWTWAIAKHFVPPVAESLLERDFDLIGQLYYKDRHNLDQWRKGWFAIEKSSLYFCLEMANAEED-SIYLR---RLQELTTSSV-------MQNGEKIDVLLLV---EKGRTLYIHGHTKLDFM-VWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKQIYLKSGDSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDALLTKELYPFWISALDTQNEKERVRKYGAFIHSLPPVNRATLAALIEHLYRVQKCSEINHMNPHNLAMVFSSCLFQTKGQ--TSEEVNVIEDLIKNYVQIFHINEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1307

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: H0ZFT5 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Taeniopygia guttata OX=59729 GN=ARAP2 PE=4 SV=1)

HSP 1 Score: 219.164 bits (557), Expect = 4.097e-54
Identity = 221/860 (25.70%), Postives = 380/860 (44.19%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIG---KLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGEQPEID------YRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDP-------DNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIR-EKLNESEGI-----SLVIVVQETDYSTKPADYXXXXXXXXXXXX----ADQSNNLRDFKNAIGQNLSPNFVPS-FSYAC--IGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVR-------DSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            KGI  + ++        +KF++ T  ++F F+    E    W+N +    KL+ D      S  +      + L+  K K IF +    T+    N++DFK G  +  I +  + VK+ D     S  +IT Y+ +  T ES     +W   +    Q++I+ T S       ++  +I  N SNR CA+CK+   +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F IIGN  AN FW  N    E+  ID        FI  KY   +F   ++T F  YK  + LN+ L   V  ++++ T+ L   GAD M    +P        A K  Q LQ+ +L          + +   D  + DP       +++  + +  ++   ++ N  +       K      DC NK  C +    +     +K     G+      + +VV ++D+     D     + ++        A+ + + R + +AI ++  P    S     C  IG +        + W+   F I+  S+    E+ +  E+  I LR   +++EL  S+        M N   I ++  V    +G T   H      F+  WY         D  +L +Q L++N+VP+ V+  I  +  +G   + ++ K G       + +    D  S  L        DV   LK F  +++D LLTK  Y  WI+A+D ++ +++   ++  I  LP +N  TL  LI  L  + K +++ QMNP NL+  F++CL     Q   ++ + ++  LI+NY  LF + +++++   + N    K KD    +   LL ++Y+
Sbjct:   64 KGIILLSAIATVRVHGESKFEVVTSHRTFVFRADKEEERNDWVNTMLNALKLLPDNNSQSRSSVTPEKSGYLELKGYKTK-IFILLQGSTVWICKNEQDFKTGFGITLIPMNVANVKQMDRAAKQSFEIITPYKSFSFTAESEKEKQDWIEAL----QQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPGPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSN-ELIELFIIIGNKRANSFWAGNLPPDEELHIDDPAEKRIAFITQKYKEGKF---RKTPF-HYKTKEQLNKALCAAVVKQDVLETLMLLFSGADAMCATGDPVYSTPYLLAKKAGQRLQMEFL----------YHNKFSDFPNYDPCFESGFSEDSSHSTFLCEFLYKVSSNAAKLPTEKKLKE-----DC-NKRWCTLESGFLSYYENDKTTTPNGMIDINEVICLVVHKSDFFLNRGDIFTFEMHLLSERVFLFGAETAQSQRKWTSAIAKHFVPPVAESLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLYFCLEMEDAEED-SIYLR---RLQELTTSSV-------MQNGERIDVLLLV---EKGRTLYIHGHTKLDFM-VWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKQIYLKNGDSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDALLTKELYPFWISALDTQNEKERVRKYRAFIRSLPPVNRATLAALIEHLYRVQKCSEINQMNPQNLAVVFSSCLFQTKGQ--TSEEVNVIEDLIKNYVQLFHINEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 875

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: H0UZX6 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Cavia porcellus OX=10141 GN=ARAP2 PE=4 SV=2)

HSP 1 Score: 218.394 bits (555), Expect = 1.380e-53
Identity = 223/852 (26.17%), Postives = 376/852 (44.13%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD-GEQPEIDY------RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL--NSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLS-INQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIRE---------KLNESEGISLVIVVQETDYSTKPADYXXXXXXXXXX--XXADQSNNLRDFKNAIGQNLSPNFVPSFS---YACIGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIY---HLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            KGI  + +V+       NKF++ T  ++F F+    E    WI+ +   +       +S  +   +    LE ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T ES     +W       +Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N    E+ ++D        FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L  N        D  SD             Q P Q  +    + Q P     +    S  +IL+ +NK+ C +L        E          +N SE I L I  ++   +T P    E  +    +    A+ S   R +   I ++  P    + +   Y  IG +        + WK   F ID  S+     + E +E    D   + +++EL  S    V   +  ++  +      +Y   H + D    H  + KA        D  +L +Q L++N+VP+ V+  I  +  +G   + +++K G       + +    D  S+ L        DV   LK F   ++D LLTK  Y  W++A+D +D +++ + +   I  LP +N  TL  +I  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD    +   LL ++Y+
Sbjct:  517 KGIIPLSAVSTVRVQGDNKFEVVTTQRTFVFRAEKEEERNDWISILSNALKLHSLTSQSQVAVAPEKCGYLE-LRGYKAKIFTVLKGSSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAESEKEKQDWIE----AVQQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLQKDEELQMDSPVEKRKNFIIQKYREGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSDT---------GLSQEPAQATFLCDFLYQVPASASKV---SSEKKILEETNKKWC-VLEGGFLSYYENDKSTTPNGTINISEVICLAIHKEDFYLNTGPVFIFEIYLPSERVFLFGAETSQAQRKWTETIAKHFVPFVAENLTEADYDLIGQLFYKDCHALDQWKKGWFAIDKSSLRFCLHMQEAQE----DRMHLRRLQELTTSTV--VQNGEKLDVLFLVEKGRTLYIHGHTKLDFTVWHTAIEKA-----AGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLENFKKDARSFKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERIKKYGAFIRTLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1327

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A0P6J175 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Heterocephalus glaber OX=10181 GN=ARAP2 PE=4 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 1.965e-53
Identity = 222/853 (26.03%), Postives = 375/853 (43.96%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKG--KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKR-DGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLAN-FDGEQPEIDY------RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL--NSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLS-INQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIRE---------KLNESEGISLVIVVQETDYSTKPADYXXXXXXXXXX--XXADQSNNLRDFKNAIGQNLSPNFVPSFS---YACIGWVILSTVS--EDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDS----NCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEIS-LLRQIYI 2990
            KGI  + +V+       NKF++ T  ++F F+    E    WI+ +   +  +    +S  +   +    LE ++G   +IFT+    ++    N++DFK G+ +  I +  + VK+ D     S  +IT YR +  T ES     +W       +Q++I+ T S       ++  +I  N SNR CA+CK+ D +WAS+NL + +C KC+G HR +GP  SK++ +  D S W N  LI +F +IGN  AN FW  N    E+ ++D        FI  KY   +F  RK  +    K+   LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L  N        D  SD             Q P Q  +    + Q P     +    S  ++L+ +NK+ C IL        E          +N SE I L I  ++   +T P    E  +    +    A+ S   R +   I ++  P    + +   Y  IG +        + W+   F +D  S+    ++ E +E    D   + +++EL  S    N E +    +        I     H + D    H  + KA        D  +L +Q L++N+VP+ V+  I  +  +G     +++K G       + +    D  S+ L        DV   LK F   ++D LLTK  Y  W++A+D +D +++ + +   I  LP +N  TL  +I  L  + K +++  MN  NL+  F++CL     Q   ++ + ++  LI NY ++F+V +++++   + N    K KD    +   LL ++Y+
Sbjct:  517 KGIIPLSAVSTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTPQSQVAVAPEKCGYLE-LRGYKAKIFTVLKGSSLWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAESEKEKQDWIE----AVQQSIAETLS-----DYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSN-ELIELFIVIGNKRANDFWAGNLLKDEELQMDSPVEKRKNFITQKYREGKF--RKTLLASLTKEE--LNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSDT---------RLSQEPAQATFLYDFLYQAPASASKV---SSEKKLLEETNKKWC-ILEGGFLSYYENDKSTTPNGTINISEVICLAIHKEDFYLNTGPVFIFEIYLPSERVFLFGAETSQAQRKWTETIAKHFVPFVAENLTETDYDLIGQLFYKDCHALDQWRKGWFALDKSSLHFCLQMQEAQE----DRMHLRRLQELTTSTMIQNGEKLDVLFLVEKGRTLYIHG---HSKLDFTVWHTAIEKA-----AGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGYRYIYQKSGDPLHISELLENFKKDARSFKLRAGKHQLEDVTGVLKRFLSDIDDALLTKELYPYWVSALDTQDEKERIKKYGAFIRTLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQ--TSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYV 1327

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:NCBI gene;Acc:103028333])

HSP 1 Score: 139.813 bits (351), Expect = 7.429e-33
Identity = 104/395 (26.33%), Postives = 186/395 (47.09%), Query Frame = 3

Query:  447 KSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKL-------IYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQP-------EIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNY-VSEPSGLNSLETAGKYHQMLQLTYLN 1586
            + R+  L ++ L  F+  +   SK  IP  S+ G+        +N  D  KF++ T  + F F+  S     +W++ +  +       + ++  ++   NS + K  + L  ++ K ++T+     +  Y N E++K GI +  I +    VK    D  +  L T YR +    E+  L ++W   +   I +A+S           ++  +I     N+ CA+C +   EWA++NL +  C +C+G HR +GP+ISK++ +  D+  W N  LI++F+++GN  AN+FW AN    +        E   RFI  KY   ++  R   +F   K+   +N  L   V++ ++  T+ L   GAD+N     P   + +  A  Y Q LQ+ +L 
Sbjct:  501 QRRWVKLDADYLRYFDNEKEVYSKRVIPTSSITGV--------ANVGD-QKFEVVTHNRIFLFRAESDSERNEWVSVLQDMTGPVRARVSNELTLNPMVNSEM-KGYLELRGLRSK-LYTVVCGDKVFLYKNIEEYKMGIGITSIDMNVGNVKE--MDRRAFDLTTPYRIFSFIAETDQLKDQWVEAMRNSIAEALS---------NYEVAEKIWAEPDNQKCADCGAPKPEWAAINLCVVFCKRCAGEHRSLGPSISKVRSLKMDKKVWTN-ELIQLFRVLGNERANQFWAANVPPSEALSVCSSSEERRRFITAKYREGKY-RRYHPLFGNQKE---INNALCINVQSNDVCETLALVFCGADVNCDTGLPDSPSPIALAVNYGQALQVEFLT 868

HSP 2 Score: 87.8113 bits (216), Expect = 6.745e-17
Identity = 52/193 (26.94%), Postives = 104/193 (53.89%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEME 2912
            +L  Q LT+ ++P+ V + I ++  +G   EG++RK G   +   + +    +  S  L  ++    DV++ LK FFR +E+ L  + + +NW+    + D  K+  +++ + N LP +N  TLR L+  L  + + +++ QMN  NL+  F   L     + +NA   +++  LI++Y  +F V +++L+ +
Sbjct: 1106 TLRQQQLTEADIPVIVERCIHYITQYGLTSEGIYRKSGVNSKIAALLEAFRRNARSVWLKEAEQQVDDVSNVLKRFFRDIEEGLFGQ-HAQNWLTTTAVSDESKRISHYQLLFNNLPRVNKATLRTLVNHLYCVQRFSEMNQMNLHNLAIVFGPTLFQTDGKDYNAG--RVVEDLIQHYIAIFHVNEQQLKRQ 1295

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1])

HSP 1 Score: 131.339 bits (329), Expect = 3.452e-30
Identity = 91/339 (26.84%), Postives = 163/339 (48.08%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDE---SDNSHLLK-ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSG 1526
            KG+  + ++  +     NKF++ T  ++F F+  +     KW + + + + ++           SH  K   + L+  K K I+       I  Y N++ F  GI +  I+ R + + RDG  S S  LIT Y+ +  T ES     EW       +Q++I+ T S       ++  +I  N SN+ CA+CK+ + +WAS+NL + +C  C+G HR +G  +SK+Q +  D S W N  ++++F ++GN+ AN+FW A     +       PE    FI  KY   R+     +    +   + L + L   V  +N+++T+      A+   +++ +G
Sbjct:  518 KGVIPLAAIQMARVAKDNKFEVVTSHRTFVFRADNEVQRNKWCSVLQERVKEQMVFGRPRFGPGSHCQKSGFLELKGTKSK-IYAAIITEQIWLYKNEQCFNTGIGISVIEARGATI-RDGK-SKSFDLITPYKTFSFTAESDRDKREWME----ALQESIAETLS-----DYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRSLGTMVSKVQSLKLDTSVWSN-EIVQLFIMLGNDRANEFWAARLPVAEELDCDASPEQRREFIVQKYREGRYRHPHPS----FSTQEELLKALCTAVTEQNLLKTVTQIFAEAEAARLADSNG 839

HSP 2 Score: 87.4261 bits (215), Expect = 8.718e-17
Identity = 64/223 (28.70%), Postives = 109/223 (48.88%), Query Frame = 3

Query: 2259 HLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE---ELEME 2912
            HL+G  +     L  A +Q      + +L +Q L++N++P+ V   I  +  +G   EG++RK G+    + + D+   D  +  L   D +  DV   LK FFR+++DP+     +  W  A    +  ++ + +KE+I  LP +N  TL  LI  L  + K  D+ QM   NLS  F   L     +      ++I+  LI NY  +FD+ +E   ++E+E
Sbjct: 1066 HLQGMGRMDFS-LWYADIQKAAGGKANTLKDQQLSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPYWKDAAKTSNKMQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGK--GEHEVKIVEDLIDNYLYVFDIDEEHKTQIELE 1285

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1])

HSP 1 Score: 131.339 bits (329), Expect = 3.481e-30
Identity = 91/339 (26.84%), Postives = 163/339 (48.08%), Query Frame = 3

Query:  543 KGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDE---SDNSHLLK-ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSG 1526
            KG+  + ++  +     NKF++ T  ++F F+  +     KW + + + + ++           SH  K   + L+  K K I+       I  Y N++ F  GI +  I+ R + + RDG  S S  LIT Y+ +  T ES     EW       +Q++I+ T S       ++  +I  N SN+ CA+CK+ + +WAS+NL + +C  C+G HR +G  +SK+Q +  D S W N  ++++F ++GN+ AN+FW A     +       PE    FI  KY   R+     +    +   + L + L   V  +N+++T+      A+   +++ +G
Sbjct:  413 KGVIPLAAIQMARVAKDNKFEVVTSHRTFVFRADNEVQRNKWCSVLQERVKEQMVFGRPRFGPGSHCQKSGFLELKGTKSK-IYAAIITEQIWLYKNEQCFNTGIGISVIEARGATI-RDGK-SKSFDLITPYKTFSFTAESDRDKREWME----ALQESIAETLS-----DYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRSLGTMVSKVQSLKLDTSVWSN-EIVQLFIMLGNDRANEFWAARLPVAEELDCDASPEQRREFIVQKYREGRYRHPHPS----FSTQEELLKALCTAVTEQNLLKTVTQIFAEAEAARLADSNG 734

HSP 2 Score: 87.4261 bits (215), Expect = 8.344e-17
Identity = 64/223 (28.70%), Postives = 109/223 (48.88%), Query Frame = 3

Query: 2259 HLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE---ELEME 2912
            HL+G  +     L  A +Q      + +L +Q L++N++P+ V   I  +  +G   EG++RK G+    + + D+   D  +  L   D +  DV   LK FFR+++DP+     +  W  A    +  ++ + +KE+I  LP +N  TL  LI  L  + K  D+ QM   NLS  F   L     +      ++I+  LI NY  +FD+ +E   ++E+E
Sbjct:  961 HLQGMGRMDFS-LWYADIQKAAGGKANTLKDQQLSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPYWKDAAKTSNKMQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGK--GEHEVKIVEDLIDNYLYVFDIDEEHKTQIELE 1180

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ENSAMXT00000019510.2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:NCBI gene;Acc:103040621])

HSP 1 Score: 122.865 bits (307), Expect = 1.215e-27
Identity = 102/387 (26.36%), Postives = 166/387 (42.89%), Query Frame = 3

Query:  453 RYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLK--ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD-------GEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            R+       L  +   +   SK  +PL ++K +  V           NK ++ T  ++F F+         W+  +   +  +  I    + H       V L   KGK   ++     +     D+DF  G+A+  + L ++ VK    D  S  + T +R +  T ES     EW       +Q++I  T S       ++  ++  N SNR CA+C++ + EWAS+NL + +C  C+G HR +G  IS+++ +  D S W N  L+ +F  +GN NANKFW  N         G  PE    F    + RK    +   +     + + LN+ L   V   +++ TM L   GAD M    +P        A K  Q LQ+ +L
Sbjct:  442 RWVKFDGENLTYYNNDKEMYSKGLVPLSAVKQVRSVGE---------NKLEVVTSQRTFVFRAEKEGERQDWLEVLQSALKSRSSISHKPSKHSSSKSGYVELRGHKGKVYLSLT-GTKVRLCKTDQDFNTGMAIAVVDLTAACVKH--VDRRSFEINTPFRSFCFTAESEREREEWIE----AVQESIVETLSNY-----EVAEKVWFNQSNRNCADCRAPNPEWASINLGVVICKLCAGQHRFLGSGISQVRSLKLDSSIWTN-ELVELFLEVGNENANKFWAFNLPLEEELHMGATPEQRATF----HRRKYRERKYRRVLGGLHNQEGLNQALCAAVLQSDVLVTMALVFSGADVMCATGDPEHSTPYLLAQKGGQRLQMEFL 802

HSP 2 Score: 98.9821 bits (245), Expect = 2.496e-20
Identity = 73/253 (28.85%), Postives = 121/253 (47.83%), Query Frame = 3

Query: 2244 SSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNK--ERMKIKDFPPLEISLLRQIYI 2990
            S    ++ G TK+    L  + +Q    RD  +LSNQ L++N+VP+ V   I  +  +G   +G+++K G  K + ++ +    D  +  L   D    DV   LK F  + ED LL K  Y  WI+A+D  + E + E +   I  LP IN  TL  L+  L  +   + + QM   +L+  F++CL     +       +++  LI NY  LF V +E++   +  N+   R K   F P    L+ ++Y+
Sbjct: 1019 SGRTIYIHGVTKQDFA-LWHSAIQLAAGRDGRALSNQQLSKNDVPIIVDSCIAFVTQYGLCYQGIYQKNGDPKRSAQLLEDFTRDARNVKLRVQDHRLEDVTDTLKHFLSQCEDALLAKELYPYWISALDEENEEDRIEKYSTYIQSLPKINRSTLAALLQHLYRVQSCSHINQMKAQSLACVFSSCLF--QTEGHTTPETRVVEDLISNYIQLFSVNEEQVRQMERENRFITRWKDTTFSPAG-DLIFEVYL 1267

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ENSAMXT00000000841.2 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like [Source:NCBI gene;Acc:103047121])

HSP 1 Score: 112.464 bits (280), Expect = 1.451e-24
Identity = 76/259 (29.34%), Postives = 126/259 (48.65%), Query Frame = 3

Query:  813 YDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF--------DGEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQ 1562
            Y++ EDF  G+ M  + +  + VK+ G   +  SLIT Y+ +  + +S      W +Q+  +I+ A+S  CS       ++   +  +  N+ CA+C S++ EWAS+NL + +C  C+G+HR +G + SK++ +  D   W    LI++F I GN  +N  W  N         D  Q E D  FI  KY    + +    I ++      LN+ L E V   ++  T+ L   GA  +     PS ++  E AG+  Q
Sbjct:  297 YNSKEDFNLGLGMTLVSMNVASVKQTGR--HGFSLITPYKSFNFSADSSKDQTTWLNQLNEVIRSALS--CS-------EVALRLWASPWNKVCADCGSSNPEWASINLLVVICEACAGVHRSIGTSRSKVRSLKLDSKIWTE-PLIKLFIIYGNKASNNVWGHNVPAAEQILPDAGQEERDA-FIKAKYCSGLYRKTHPLISNQ----TLLNQRLCEVVCGVDVEETLCLLCSGAKVLTDPQSPSAISIAENAGQALQ 538

HSP 2 Score: 58.151 bits (139), Expect = 5.692e-8
Identity = 46/184 (25.00%), Postives = 83/184 (45.11%), Query Frame = 3

Query: 2367 NNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNS--DPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEME 2912
             +VP  + + I H+ L+G ++EGL+R+ G+  +  ++   L S P   VL     D  DVA   K   R++ D L+      +W  A        + + ++ +++KL   N  TL  L   L  +  ++ V +M   NL+  F   L    +   N   +++   LI ++  +F    E +E E
Sbjct:  762 GSVPPELERCISHITLYGLKVEGLYRRCGTGTKINQLVKDLHSAPAETVLGTGELDIVDVAGTFKQLLRQM-DELIPTPQRPDWAKAAAAALETDRLQQYRRLVSKLDPDNRATLAALCGHLYIVQLHSQVNRMTAHNLAVVFVPTLF--QELAMNTDMVRLTKELIIHHTLVFLSHPEAVEDE 942

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000232.1 (pep scaffold:Pmarinus_7.0:GL480628:15362:26221:1 gene:ENSPMAG00000000209.1 transcript:ENSPMAT00000000232.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.145 bits (261), Expect = 2.322e-24
Identity = 82/358 (22.91%), Postives = 157/358 (43.85%), Query Frame = 3

Query:  387 DRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALV--------------SLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQ 1418
            D+    GP   + QK       RY    SN   ++ K    +S VQ  L    G    D+          KF++ T  ++F F+  S      W++ + + +  ++  +    S L  A V              +LE     +++ +     +  + +++DF+  + +  I++  + V+    +   + L T+++ +    E+    +EW   +   I  ++S           D+  +I  N  NR CA+C +   +WASVNL + +C +C+G HR +G  +SK++ +  D++ W   NLI +FQ +GN   NKFW A+    +       ++     +R   R+E +F KY++ +
Sbjct:    7 DKQAPQGPY--LFQKRWVKSDGRYLYYYSNDKEMYSKGVLPLSAVQEVLTQTGG----DA----------KFEVVTQTRAFVFRADSEAERAGWVSALREAVQAQRSPEGGVASMLHSAGVIPGEALWGEQEKRGTLELRGKAKLYVVGCSDRLWLFKSEQDFRTSLGITCIEMNVANVR--AVEKKGIDLTTAFKTFSFMAENERERDEWLETMRDSIATSLSHL---------DVAKQIWANEHNRRCADCGAAWPDWASVNLCVVICKRCAGEHRNLGQTVSKVRSLKMDKNIWTK-NLIELFQELGNAQVNKFWAASVPPSEA------VDPSSEAER---RREYVFAKYREGR 327

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007633.1 (pep scaffold:Pmarinus_7.0:GL488501:137984:146551:-1 gene:ENSPMAG00000006898.1 transcript:ENSPMAT00000007633.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 3.594e-23
Identity = 65/191 (34.03%), Postives = 95/191 (49.74%), Query Frame = 3

Query: 1050 DIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKETIFDKYK------------DSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSG-LNSLETAGKYHQMLQLTYL 1583
            DI   I    +NR CA+C +    WAS+NL + +C  C+G HR +GPNISK++ +  D+  W + +LI +F  IGN   N+FW AN    + EID   + +        ER+E +  KY+            D   LNR L   V T +++ +M L + GAD+      S   + L  A +  Q LQL  L
Sbjct:  209 DIADRIWALPANRLCADCGAAKPAWASINLCVVICKLCAGQHRALGPNISKVRSLKMDKKIWTD-DLIELFVQIGNERVNEFWAANVPPSE-EIDPASMPN--------ERREFVVAKYRSGKYRRYHEFFGDQAELNRALCSAVVTSDVLESMALVYCGADVTGAPGCSPDDDPLLLAEQAGQKLQLQML 389

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003939.1 (pep scaffold:Pmarinus_7.0:GL477112:28457:91290:-1 gene:ENSPMAG00000003551.1 transcript:ENSPMAT00000003939.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.9669 bits (219), Expect = 5.750e-18
Identity = 47/149 (31.54%), Postives = 86/149 (57.72%), Query Frame = 3

Query: 2370 NVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSD 2816
            +VP  + K++ ++++HG   EG++RK G+  + + +  QL +D NS  L +   + + S LK + R+L  PL+T   Y+ ++ AV + + ++K +    II +LP +NY TL  +IF LV I +  D  +M+ + L+  F  C++   D
Sbjct: 1128 SVPFLLEKLLNYIEIHGLYTEGIYRKSGANTKVKELRQQLDNDVNSVNLDDYQVHVIGSVLKQWLRELPVPLMTLDLYDEFLRAVGVPEKKEKIKAVYSIIGQLPSVNYSTLERIIFHLVRIAQYEDTNRMSCNALAIVFAPCILRPPD 1276

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: GIT2 (GIT ArfGAP 2 [Source:HGNC Symbol;Acc:HGNC:4273])

HSP 1 Score: 72.7886 bits (177), Expect = 1.875e-13
Identity = 52/179 (29.05%), Postives = 80/179 (44.69%), Query Frame = 3

Query: 1092 CAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF-DGEQPEIDYR--------------FINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            C  C  +D  WAS+N  + +C +C  +HR +G +IS ++ +    S W   +LI++ Q + +N AN  W  +  D  Q +   R              FI  KY    F  R     D    +  L+R+L   V+T N+  +++L  +GA  NY +   G   L  A K  Q LQ   L
Sbjct:   10 CKGCTISDPGWASINRGVLVCDECCSVHRSLGRHISLVKHL--RHSQWPT-SLIQMVQTLVSNGANSIWEHSLLDPAQIQSGKRKANPHDKVHPTKAEFIKAKYQMLSFVHRMPCREDDNIMATDLSRQLHSSVRTGNLETSLRLLSLGAQANYFNPDKGNTPLHVAAKAGQTLQAELL 185

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000404.1 (pep scaffold:Pmarinus_7.0:GL476366:629540:661972:1 gene:ENSPMAG00000000361.1 transcript:ENSPMAT00000000404.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.7886 bits (177), Expect = 4.309e-13
Identity = 56/188 (29.79%), Postives = 87/188 (46.28%), Query Frame = 3

Query: 2367 NNVPLPVSKMIRHLQLH-----GTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSE----KKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNY-QDLFDVTQEE 2900
              VPL V  M++ L+ H     G + EGLFR  GSV+  ER+     +D  S     +D   VA  LKLF R+L D ++      +++ A   RDS     +  E  + ++ +LP  N+  LR L   LV + ++ +V  M+P NL T F       S  M      Q++  +   +  D   + QE+
Sbjct:   18 RTVPLVVETMVQFLEEHVSVHTGLESEGLFRVSGSVRAVERLRQAWEADVTSDGRGQADVSSVAGLLKLFLRELPDGVVPASLLPSFLQA--HRDSAGDEMRLAESLRLLLAQLPGENHALLRYLCSFLVRVAQHQEVNLMSPQNLGTVFGPNFFRVSPGMEGIAEQQVVNRVTARFITDFLSIFQED 203

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: AGE2 (ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000001306])

HSP 1 Score: 65.4698 bits (158), Expect = 1.154e-11
Identity = 36/116 (31.03%), Postives = 63/116 (54.31%), Query Frame = 3

Query: 1041 PGEDIMHEINKNASNRFCAECKST-DIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERK 1385
            P +  +  + ++  N  CA+CK+     WAS +L + +C KC+G+HR +G +ISK++ +  D  TW+  +L+++ Q   N  AN ++ A       E+  R I D  S + F + K
Sbjct:    6 PVKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSV--DLDTWKEEHLVKLIQFKNNLRANSYYEATLAD---ELKQRKITDTSSLQNFIKNK 116

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: AGE1 (ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000002932])

HSP 1 Score: 60.077 bits (144), Expect = 1.245e-9
Identity = 45/148 (30.41%), Postives = 74/148 (50.00%), Query Frame = 3

Query: 1053 IMHEINKNASNRFCAECKST-DIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQ---------IIGNNNANKFWLANFDGEQPEIDY-RFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENI 1463
            I+ +I+K  SN  C +C ST  +EW S+NL   LC KCSG+HR +G +ISKI+ +  D  T  +  L+ + Q          I  +N   F +        + +  +FI DKY  K+F      + D  +  +A  + LI+ +  +++
Sbjct:  175 IVRKIDK--SNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLDNFT--SLELMHLLQNNVSNSNVNAIYESNLRNFPVKKITANSDDSERSKFIIDKYQFKKF------VIDSNQGREASLKSLIKAIHLDSV 312

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: GLO3 (ADP-ribosylation factor GTPase activating protein (ARF GAP); involved in ER-Golgi transport; shares functional similarity with Gcs1p [Source:SGD;Acc:S000000924])

HSP 1 Score: 58.151 bits (139), Expect = 5.332e-9
Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 3

Query: 1047 EDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ 1322
            + +  ++  N  NR C +C + +  W SV   + LC +CS +HR MG +I+ ++    D+ T  N   +R F++ GN+ A  F+L N +G+Q
Sbjct:   16 QQVFQKLGSNMENRVCFDCGNKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLDKWTINN---LRRFKLGGNHKARDFFLKN-NGKQ 103

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: RGD1 (GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization [Source:SGD;Acc:S000000464])

HSP 1 Score: 56.225 bits (134), Expect = 2.343e-8
Identity = 49/190 (25.79%), Postives = 82/190 (43.16%), Query Frame = 3

Query: 2364 QNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVL-------TNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEME 2912
            Q+ VP  V + I  +   G   EG++RK  +V +  ++ +++  DP +  +       ++SD Y V S LK FF  L D +L K         + I D   +  +   +I  LP   Y TLR L+F L  +  +    +MN   L   +   +   +    N  N QI+   +     L +V+ +  E E
Sbjct:  482 QDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEV-----LLEVSDQAFEPE 666

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: RGA2 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p; RGA2 has a paralog, RGA1, that arose from the whole genome duplication [Source:SGD;Acc:S000002787])

HSP 1 Score: 56.225 bits (134), Expect = 3.146e-8
Identity = 58/189 (30.69%), Postives = 87/189 (46.03%), Query Frame = 3

Query: 2418 GTQIEGLFRKVGS---VKEAERIYDQ---LISD---PNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAV--------------DIRDSEKKFEYFK-------EIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLI---SGSDQMFNAKNLQ-ILPYLIRNYQDLF 2882
            G  +EGL+RK GS   V+E E  + Q   L SD   P    L N D + VAS LK + RKL DP+L+   Y+  I  V                 DS +K   ++       EI   LPV + + L++L   +  + + ++   MN  NLS  F   LI    G   + + K    I+ +++ NY+D+F
Sbjct:  818 GLNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIHDFDGEKDIVDMKERNYIVEFILGNYRDIF 1006

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO34673 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK8])

HSP 1 Score: 117.857 bits (294), Expect = 1.795e-26
Identity = 78/255 (30.59%), Postives = 127/255 (49.80%), Query Frame = 3

Query:  771 KRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTD-IEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANK---FWLANFDGEQPEID----YRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYV 1511
            KR +      +I YYD  +DF++   +H I+ + + VK+D N  N  ++ITS + +    E+    + W   +   IQ  +S            ++  +  N SNR CA+C + D    ASVN  + +C  C G HR +G NISK + +  D+  W N +L  +   IGN NANK   F + + D  +P+ D      FI  KY  K++S+    I  +Y +   L + L E V+T++++RT +L     ++ YV
Sbjct:  894 KRRYVAIKGGSICYYDTYDDFQFETPIHSIEAQLASVKQDPNHRNRFNIITSQKTFSFQVENDFEVSSWIEAVQRAIQIGLSDPA---------VLEYVFTNPSNRKCADCGNKDPYPHASVNHLVCICGNCCGSHRSLGSNISKPRSLLMDKKIW-NDDLKELMVKIGNENANKLLEFKIPDDDRIRPDADSAKRREFICAKYEYKKYSK----ILPEYGNVDVLGQALRESVQTDDVMRTFELIINRVNVKYV 1134

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO43007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZU7])

HSP 1 Score: 77.411 bits (189), Expect = 2.519e-14
Identity = 46/148 (31.08%), Postives = 83/148 (56.08%), Query Frame = 3

Query: 1065 INKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERK--ETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADM 1502
            I K   N++CA+C +   +WAS+NL IT+C +CSG+HR MG ++SK++ +  D+  W +G+ +   + +GN   NK + AN + + P++     + K+ R+ F + K  E  F     ++ L+ E+ E + T    R  +L  I  ++
Sbjct:  515 IRKVEGNKYCADCSAPRPDWASINLGITVCIECSGVHRSMGVHVSKVRSLTLDK--W-DGDTVEFMEAMGNTKVNKIFEANLN-DFPKLTRD--SGKHDRQAFIKLKYVEQKFYSPIPAEGLDPEVAEALITRPGDREDELLDISQEL 656

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO34178 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ28])

HSP 1 Score: 75.0998 bits (183), Expect = 1.573e-13
Identity = 46/159 (28.93%), Postives = 83/159 (52.20%), Query Frame = 3

Query: 1053 IMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDE-STWENGNLIRIFQIIGNNNANKFWLANFDGEQ-PEIDYR------FINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMN 1505
            I+ ++ +   N  CA+C S D  W S NL +  C +CSG+HR MG ++S++Q I  D   T E    + + + IGN   N+   A  D +Q P  + +      FI+ KY + +++++        +  + + +EL + VK+ +I+  +Q F  G D++
Sbjct:  417 IVKQVQRLPGNDTCADCTSKDPTWLSTNLGVLTCIECSGVHRGMGVHVSRVQSITLDNIGTAE----LLLAKAIGNGGFNEIMEATLDIDQKPTANSKMDEKKEFIHAKYIKHQYAQK------SGESPEKVLQELHQAVKSRDILAVLQGFGEGVDLS 565

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO37809 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEL6])

HSP 1 Score: 72.7886 bits (177), Expect = 5.021e-13
Identity = 37/119 (31.09%), Postives = 63/119 (52.94%), Query Frame = 3

Query: 1041 PGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDY--------RFINDKYSRKRF 1373
            P + I+  +     N  CA+C   D +WAS+NL + LC +CSG+HR +G ++SK++ +  D   WE  +L ++   +GN+  N  + A   G+  +I++         +I  KY   RF
Sbjct:  403 PPKSILEAVRSVPGNEVCADCNHNDPKWASINLGVVLCIECSGIHRSLGVHVSKVRSLTLD--AWEPEHL-KLMSELGNSLINSIYEAKIAGDHKKINHLSNRSDREAWIKSKYIYHRF 518

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO33091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST58])

HSP 1 Score: 66.6254 bits (161), Expect = 5.590e-13
Identity = 37/114 (32.46%), Postives = 62/114 (54.39%), Query Frame = 3

Query: 1047 EDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANF--DGEQPEIDY---RFINDKYSRKRF 1373
            + I+ ++ K   N++CA+C +    WAS NL + +C +C+G+HR +G +ISK++ +  D  +W    +  I Q  GN  A  +W      D  +P+ D     FI  KY +K+F
Sbjct:   17 QAILVDMLKEEKNKYCADCAAKGPRWASWNLGVFICIRCAGIHRNLGVHISKVKSVNLD--SWTEEQMASI-QSWGNRRAGLYWECYLPEDFRRPQTDSAMEAFIRKKYEQKKF 127

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: ENSORLT00000045891.1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:NCBI gene;Acc:105356443])

HSP 1 Score: 132.109 bits (331), Expect = 2.034e-30
Identity = 95/346 (27.46%), Postives = 163/346 (47.11%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYD---KQQIDESDNSHLL----KALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFD-------GEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD-MNYVSEPSGLNSLETAGKYHQMLQLTYLN 1586
            NKF++ T +++F F+        +WI  +           Q   +  SHL     + L+ L   KGK + ++     +     ++D+K G+ +  ++L ++ + RD  D     + T ++ +  T ES     EW       IQ++I  T S       ++  +I  N +NR CA+C++   EWAS NL + +C KC+G HR +GP+ISK++ +  D S W N  L+  F  +GN  AN FW AN         G   E    FI  KY  +++      + + ++    LN+ L   V T ++++TM L   GA+ M    +P+       A +  Q +Q+ +L+
Sbjct:  493 NKFEVITSLRTFIFRAEGEGERQEWIEALQTATQPPACSSQKRSNTLSHLSSTNKRGLLELRGYKGKVLVSLVGS-KVRLCKTEQDYKAGLGISEVELTAANI-RD-MDRRGFEINTPFKNFCFTAESEQEKAEWVE----AIQESIVETLSDY-----EVAEKIWFNEANRSCADCRAPQPEWASTNLGVVICKKCAGQHRFLGPSISKVRSLKLDSSIWSN-ELVEFFLEVGNKKANSFWAANLPLEEELHIGASTEQRATFIRRKYKERKYRR----LLEGFEYVVQLNQALCASVVTPDVLQTMALVFTGANVMCATGDPTYSTPYLLAQRAGQKVQMEFLH 821

HSP 2 Score: 87.4261 bits (215), Expect = 8.137e-17
Identity = 59/197 (29.95%), Postives = 96/197 (48.73%), Query Frame = 3

Query: 2334 STSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-EMEK 2915
            S +LS Q LT+N +P+ +   I  +  +G   EG++ K+G       + ++   D  S  L   +    DV   LK F   LED LL K  Y  W++A+D RD   + + +   I  LP IN  TL  L+  L  I + + +  M  + L+  F+ C      Q    + + ++  LIRNY  LF V ++++ +ME+
Sbjct: 1063 SKALSEQQLTKNGIPIILESCIAFVTQYGFCQEGVYEKLGDPTRVGLLLEEFNRDARSVKLREKEHKLEDVTDTLKSFLNHLEDALLIKELYPYWVSALDERDESLRVKKYSTFIESLPKINKMTLDALLQHLYRIHQCSHLNHMPSEKLAAVFSCCFFQTQGQ--TTQEISVVQDLIRNYVTLFRVNEDQVQQMER 1257

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:NCBI gene;Acc:101162821])

HSP 1 Score: 128.257 bits (321), Expect = 2.895e-29
Identity = 92/347 (26.51%), Postives = 166/347 (47.84%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWIN----HI-GKLIYDKQQIDESDNSHLLK-ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVS--------EPSGLNSLETAGKYHQMLQ 1571
            NKF++ T  + F F+  +     +W+     HI  +L++ +++      SH  K  ++ L+  K K ++T      I  + +++ F+ GI +  I+ R + + RDG    S  LIT Y+ +  T ES     +W       +Q+AI+ T S       ++  +I  N SNR CA+CK+ + +WAS+NL + +C  C+G HR +G  +SK+Q +  D S W N  ++++F ++GN+ AN FW A+    +       PE    FI  KY   RF          +   + L + L   +  + +++T+    + A+   ++         P G +     G Y +++Q
Sbjct:  572 NKFEIVTSNRIFVFRTDNEVLRRRWVTTLQEHIRDQLVFGRRRF--GPGSHCQKHGVLELKGTKSK-VYTAISTDQIWLHKSEQCFRNGIGITVIEARGATI-RDGKH-RSFDLITPYKSFSFTAESERDKRDWME----ALQEAIAETLS-----DYEVAEKIWSNRSNRMCADCKAVNPDWASINLCVVICKNCAGQHRSLGSMVSKVQSLKLDTSVWSN-EIVQLFIMVGNDRANDFWAAHLSQSEELDCDASPEQRKDFITQKYKEGRF----RLAHPAFSTHEELLKALCTALSEQTLLKTVTQIFLEAESARLTGDSRRQHDAPQGYSPSTDPGVYDEIMQ 899

HSP 2 Score: 88.5817 bits (218), Expect = 3.623e-17
Identity = 59/196 (30.10%), Postives = 97/196 (49.49%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE---ELEME 2912
            +L  Q +++N++P+ V   I  +  +G   EG++RK G+      + ++   D  +  L   D +  DV   LK FFR+++DP+     +  W  A  I    ++ E +KEII  LP +N  TL  LI  L  + K  D+ QM   NLS  F   L     +      ++I+  LI NY  +FD+ +E   ++E+E
Sbjct: 1127 TLREQQMSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKTRIRLLMEEFRKDARNVKLRIGDHFIEDVTDVLKRFFREIDDPIFMAELHAFWQEAAKIPQKRQRLERYKEIIRSLPRVNQTTLAALIGHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGK--GEHEVKIVEDLIDNYLFVFDIDEEHQTQIELE 1320

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:NCBI gene;Acc:101162821])

HSP 1 Score: 128.257 bits (321), Expect = 3.086e-29
Identity = 92/347 (26.51%), Postives = 166/347 (47.84%), Query Frame = 3

Query:  594 NKFKLETPVKSFKFQCSSHENAGKWIN----HI-GKLIYDKQQIDESDNSHLLK-ALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQ-------PEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVS--------EPSGLNSLETAGKYHQMLQ 1571
            NKF++ T  + F F+  +     +W+     HI  +L++ +++      SH  K  ++ L+  K K ++T      I  + +++ F+ GI +  I+ R + + RDG    S  LIT Y+ +  T ES     +W       +Q+AI+ T S       ++  +I  N SNR CA+CK+ + +WAS+NL + +C  C+G HR +G  +SK+Q +  D S W N  ++++F ++GN+ AN FW A+    +       PE    FI  KY   RF          +   + L + L   +  + +++T+    + A+   ++         P G +     G Y +++Q
Sbjct:  528 NKFEIVTSNRIFVFRTDNEVLRRRWVTTLQEHIRDQLVFGRRRF--GPGSHCQKHGVLELKGTKSK-VYTAISTDQIWLHKSEQCFRNGIGITVIEARGATI-RDGKH-RSFDLITPYKSFSFTAESERDKRDWME----ALQEAIAETLS-----DYEVAEKIWSNRSNRMCADCKAVNPDWASINLCVVICKNCAGQHRSLGSMVSKVQSLKLDTSVWSN-EIVQLFIMVGNDRANDFWAAHLSQSEELDCDASPEQRKDFITQKYKEGRF----RLAHPAFSTHEELLKALCTALSEQTLLKTVTQIFLEAESARLTGDSRRQHDAPQGYSPSTDPGVYDEIMQ 855

HSP 2 Score: 88.5817 bits (218), Expect = 3.334e-17
Identity = 59/196 (30.10%), Postives = 97/196 (49.49%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQE---ELEME 2912
            +L  Q +++N++P+ V   I  +  +G   EG++RK G+      + ++   D  +  L   D +  DV   LK FFR+++DP+     +  W  A  I    ++ E +KEII  LP +N  TL  LI  L  + K  D+ QM   NLS  F   L     +      ++I+  LI NY  +FD+ +E   ++E+E
Sbjct: 1083 TLREQQMSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKTRIRLLMEEFRKDARNVKLRIGDHFIEDVTDVLKRFFREIDDPIFMAELHAFWQEAAKIPQKRQRLERYKEIIRSLPRVNQTTLAALIGHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGK--GEHEVKIVEDLIDNYLFVFDIDEEHQTQIELE 1276

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: ENSORLT00000040486.1 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 [Source:NCBI gene;Acc:101156673])

HSP 1 Score: 102.449 bits (254), Expect = 1.734e-21
Identity = 74/264 (28.03%), Postives = 120/264 (45.45%), Query Frame = 3

Query:  813 YDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQP-------EIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSGLNSLETAGKYHQMLQLTYL 1583
            Y N ++F+ GIA   + L  + VK  G  S    L    +   LT ES      W + +   I  A+S  CS+       +   + +N  N+ CA+C   + +WASVNL +++C  C+  HR +  N+SK++ +  D   W    +I++F   GN  AN+ W       +        E   +FI DKYSR R+      +         + + L + V T ++  TM L   GA +   S+P   + +  A K +Q LQ+ +L
Sbjct:  441 YTNKDNFQLGIASFIVPLTVACVKPTGKQS--FILTVPQKTLNLTVESNKDLTTWLNCLEAAICSALS--CSQ-------VALRLRENPHNKVCADCGEANPDWASVNLLLSICKSCADHHRNLSSNLSKVRSML-DTKIWTEP-IIQLFVTYGNKLANQVWAPAVPAAEQLHPKSTDEERSKFIQDKYSRGRYRR----VHPLSSSRAMMEQRLCQVVCTSDLEETMSLICSGAKV-CPSDPQSPSPISLAEKANQALQMQFL 686

HSP 2 Score: 57.3806 bits (137), Expect = 1.009e-7
Identity = 41/175 (23.43%), Postives = 81/175 (46.29%), Query Frame = 3

Query: 2364 QNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDP--YDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLF 2882
            Q++V   + + I H+  +G ++EG++R+ G   +  ++ + L + PNS  L   +    D  SALK + R  +D ++     + W+ A    D   +F+ ++ ++ +LP  N  TL  L      +   +   +M+  NL+      L     Q+ N   +Q+    I ++  LF
Sbjct:  914 QSSVSPAIERCISHITTYGLKVEGVYRRCGLATKVNKLVEALKTSPNSAPLEGDEQGVLDACSALKKYIRD-QDSIVPTTQRQRWLQAAANPDESCRFKEYRRLLRQLPDNNKATLNALFGHFYMVQVFSQENKMSAYNLAVVLAPSLF----QVMNQDMIQLTKEFIIHHTLLF 1083

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925])

HSP 1 Score: 90.1225 bits (222), Expect = 7.049e-18
Identity = 61/195 (31.28%), Postives = 106/195 (54.36%), Query Frame = 3

Query: 2340 SLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY--DVASALKLFFRKLEDPLLTKLYYENW--IAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEME 2912
            +LS Q LT+ +VP+ V   I  +  +G + EG++RK G       + ++   D  S  L   +    DV++ LK FFR+LED L T  +  +W  +AA D+ +S  K   +K+++N+LP +N  TL+ LI  L  +   +D+ QMN  NL+  F   L     + + A   + +  LI++Y  +F+V +++L+ +
Sbjct:  195 TLSEQQLTETDVPVIVLSCISFITQYGLKSEGIYRKSGVNSRVAALCERFHRDARSLCLKEGEHQVDDVSNTLKRFFRELEDGLFTSEHARDWLTVAAGDLENS--KISQYKDLLNRLPRVNRATLQALINHLYCVQCFSDLNQMNLHNLAIVFGPTLFQTDGKDYTAG--RAIEDLIQHYILIFEVDEQQLKRQ 385

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000006535.1 (SMESG000006535.1)

HSP 1 Score: 2349.7 bits (6088), Expect = 0.000e+0
Identity = 1207/1213 (99.51%), Postives = 1210/1213 (99.75%), Query Frame = 3

Query:   69 MSDNERILETNWKIEDFDRNIXXXXXXXRNGSLRTYLSEEGDDVISVSCKDIEGESVXXXXXXXXXGMPVFSQPLMKNYAKSPNKTIKSDNIPFPKLPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSGLNSLETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQETDYSTKPADYXXXXXXXXXXXXADQSNNLRDFKNAIGQNLSPNFVPSFSYACIGWVILSTVSEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFPPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKELLTKQLRIEQSMTSKSLFGKLFKENTNTQNISIFEDRKVDDFHMEHLVYPDENLIEVIQNSEKCDVPSKWIFKINKYTLDADSTSKSFQCQASLSMSSKNRVIIELTEKHELIICRNDQTQXXXXXXXXXXXFRSCEDNKNFVAFEYRKNQSSTMPSVLQXXXXXXXXXXXXXXXXXETDYFNFLKHYDRFKLVEIKYPESRSQLTASTVI 3707
            MSDNERILETNWKIEDFDRNIPKPKPPPRNGSLRTYLSEEGDDVISVSCKDIEGESVDDLDLPDDLGMPVFSQPL+KNYAKSPNKTIKSDNIPFPKLPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIM EINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKE IFDKYKDSQALNRELIECVKTENIIRTMQLFHIGAD+NYVSEPSGLN+LETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQETDYSTKPADYVESGISVIEISSADQSNNLRDFKNAIGQNLSPNFVPSFSYACIGWVILSTVSEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDF PLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKELLTKQLRIEQSMTSKSLFGKLFKENTNTQNISIFEDRKVDDFHMEHLVYPDENLIEVIQNSEKCDVPSKWIFKINKYTLDADSTSKSFQCQASLSMSSKNRVIIELTEKHELIICRNDQTQDLIIKIKDLILFRSCEDNKNFVAFEYRKNQSSTMPSVLQIFSFRSRSSFNIIHFSNETDYFNFLKHYDRFKLVEIKYPESRSQLTASTVI
Sbjct:    1 MSDNERILETNWKIEDFDRNIPKPKPPPRNGSLRTYLSEEGDDVISVSCKDIEGESVDDLDLPDDLGMPVFSQPLLKNYAKSPNKTIKSDNIPFPKLPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMREINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKEAIFDKYKDSQALNRELIECVKTENIIRTMQLFHIGADINYVSEPSGLNALETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLSINQNPKEFRIILIWKSCIQILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQETDYSTKPADYVESGISVIEISSADQSNNLRDFKNAIGQNLSPNFVPSFSYACIGWVILSTVSEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKIEELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQSWYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKLYNKERMKIKDFTPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKELLTKQLRIEQSMTSKSLFGKLFKENTNTQNISIFEDRKVDDFHMEHLVYPDENLIEVIQNSEKCDVPSKWIFKINKYTLDADSTSKSFQCQASLSMSSKNRVIIELTEKHELIICRNDQTQDLIIKIKDLILFRSCEDNKNFVAFEYRKNQSSTMPSVLQIFSFRSRSSFNIIHFSNETDYFNFLKHYDRFKLVEIKYPESRSQLTASTVI 1213

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070925.1 (SMESG000070925.1)

HSP 1 Score: 127.872 bits (320), Expect = 2.011e-29
Identity = 113/435 (25.98%), Postives = 196/435 (45.06%), Query Frame = 3

Query:  357 LPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPV----KSFKFQCSSHENAGKWINH----IGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIE--PKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSN--------SLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDG-EQPEIDYR-FINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFH-IGADMN--YVSEPSGLNSLETAGKYHQMLQLTYLNSQ 1592
            L C SE ++     +H  ++  +++    + + Y VL+ + +I+F+K    +S  ++P+ +              K +CN+F  +  +     +F F          WI +    IG  +  K  ID +       A V ++ + G  +F +     + +  + + ++    I  H +  +   VK D  D++        SL LI  +  +K++F+  +   EW      I+ KA+      N     +++ EI +N SNR CA+C S D EW S+NL + +C  C+G+HR  G + S+IQ    DE  W +  LI+I + IGN  +N FW  N         DY  F+ +KY  K+F + +     +Y     L +     V  +++  TM+L+H I  D N  +V E      LE A   +Q LQ  +L+ Q
Sbjct:    3 LLCLSELEEQHI--FHSSLILHLKQ----QSNMYCVLIESYMIIFKKSTDIISFKRLPITN------------KTKVECNEFGDQFSIIIRENTFTFSSPDVTIIETWIKNLNFLIGNFVLTKPLIDYN------YAEVKIDQIGGSIVFILLFCNDYNLIIFSSLKEHSDNIVTHVVNCKFYSVKNDSRDNSIASRSTIKSLVLIGKHLSFKISFKDESTLKEW----ECILLKAVKTAFGINEN---EVLTEIYENESNRCCADCGSPDPEWISINLSVIICINCAGIHRSFGTSFSRIQSAVLDECIWSDSYLIKILKTIGNEKSNSFWYKNQRKLTSTSTDYSLFVKNKYVSKKFIDDEFINLSEYDFKSHLQKS----VAADDVFLTMRLWHSINFDYNSEFVEEL-----LEIARNSNQFLQEKFLSVQ 397

HSP 2 Score: 65.4698 bits (158), Expect = 2.938e-10
Identity = 63/265 (23.77%), Postives = 129/265 (48.68%), Query Frame = 3

Query: 2382 PVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDP-----YDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-EMEKLYNKERMKIKDFPPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKE---LLTKQLRIEQSMTSKSLFGKLFKEN 3149
            P++KMI  +   G + EG+FR  G++K+   ++  +    N++ +   DP     YDV+S LK +FR L++P++T   ++ +  A+   +  +K   +KE ++ LP  NY   R L+ L   I  +   T+M+  +L+ S  +      D +    + +I+  LI N+  LFD + +++ ++E+      +  +        ++R  YI P +           R S  KK +F  +    ++  + +++ +T K +  +LF ++
Sbjct:  631 PINKMISFIISRGLKSEGIFRICGTIKKVNILHKSIEKSGNNFFI---DPLIYNVYDVSSCLKKYFRSLDEPIITSNLFDIFRGALIEENQSRKITLYKEGLSFLPRDNYSVFRDLLELFYMIQMSVTDTRMDCSSLAIS-VSSSFISFDHINTEISSKIMKELIENFIALFDYSGKKINDLERFVAGPEIVAQ-------KIIRNFYIHPNINSVTI------RNSESKKLNFIDKDANFVSVIINVDEYVTVKQIIERLFTDS 878

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070668.1 (SMESG000070668.1)

HSP 1 Score: 126.716 bits (317), Expect = 4.719e-29
Identity = 119/426 (27.93%), Postives = 194/426 (45.54%), Query Frame = 3

Query:  357 LPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLI--YDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSN----SLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGED-IMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEI----DYRFINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFH---IGADMNYVSEPSGLNSLETAGKYHQMLQLTYLNSQ 1592
            + C SE +DN  +  H  +     K+  S    Y  L+  +LI+F+     +S  ++P+     + ++D        + N+F +      + F  S       W+N I  L+  Y+  Q++    + +        NV    I     ++ +  Y+N ++    I  H I L+   ++   + S+     L L      +K+ FES  L NEW     II+ +AI+         GE+ I+ +I  N SN+ CA+C   + EW S+NL + LC  CSGLHR +  + S+IQ    D+  WE+  LI I + IGN N+N FW  N + ++  I    D   IN KY  K+F    +T F    D++  NR L   V T+++  TM+L+H      D  ++ E      L  A   +Q LQ  +L+ Q
Sbjct:    3 VTCLSEIEDN--ILIHSNL-----KVNGSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYID--------NSNQFLILLGNFQYLFMNSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSS-YILIRSDEYLLHIYENLDEHAQNICSHVINLKFYSLENSRSLSSVNNRCLKLFGKSITFKIKFESSELVNEW----KIILSEAINIA----FMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCISCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW--NKNKQKLSIIFPSDLSEINSKYIEKKFI---DTEFINLSDNEIKNR-LRSSVATDDVFLTMKLYHSIKFPYDSEFIKEI-----LLIARNSNQYLQEKFLSVQ 393

HSP 2 Score: 79.337 bits (194), Expect = 1.665e-14
Identity = 71/264 (26.89%), Postives = 122/264 (46.21%), Query Frame = 3

Query: 2382 PVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY-----DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-----EMEKLYNKERMKIKDFPPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKELLTKQLRIEQSMTSKSLFGKLFK 3143
            P+ KMI  +   G + E +FRKVG+V++   +Y+ +   PN + +   DP      DVAS  K +FR   +P++T   +  +  A  + ++  K    +  ++ +P INYQ L   + LL  I K  D  +M+  +L+ S    +IS  D+     + +IL  LI  ++ +F  + +E       +E    KE + I++F           YI P L+ FL    N  +  G         ++  ++ I Q  T K +  KLF+
Sbjct:  623 PIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFI---DPNVYNVNDVASCFKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLLKTVELLYMIQKFADENKMDSKSLALSTALSIIS-EDENHREISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREF-----------YIHPFLKNFLLIPTNENKRVGFLDRGISFSMI--RMTINQCATVKQVVQKLFR 869

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070925.1 (SMESG000070925.1)

HSP 1 Score: 117.087 bits (292), Expect = 3.198e-26
Identity = 83/264 (31.44%), Postives = 127/264 (48.11%), Query Frame = 3

Query:  840 GIAMHRIQLRSSGVKRDGNDSN--------SLSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDG-EQPEIDYR-FINDKYSRKRFSERKETIFDKYKDSQALNRELIECVKTENIIRTMQLFH-IGADMN--YVSEPSGLNSLETAGKYHQMLQLTYLNSQ 1592
             I  H +  +   VK D  D++        SL LI  +  +K++F+  +   EW      I+ KA+      N     +++ EI +N SNR CA+C S D EW S+NL + +C  C+G+HR  G + S+IQ    DE  W +  LI+I + IGN  +N FW  N         DY  F+ +KY  K+F + +     +Y     L +     V  +++  TM+L+H I  D N  +V E      LE A   +Q LQ  +L+ Q
Sbjct:   21 NIVTHVVNCKFYSVKNDSRDNSIASRSTIKSLVLIGKHLSFKISFKDESTLKEW----ECILLKAVKTAFGINEN---EVLTEIYENESNRCCADCGSPDPEWISINLSVIICINCAGIHRSFGTSFSRIQSAVLDECIWSDSYLIKILKTIGNEKSNSFWYKNQRKLTSTSTDYSLFVKNKYVSKKFIDDEFINLSEYDFKSHLQKS----VAADDVFLTMRLWHSINFDYNSEFVEEL-----LEIARNSNQFLQEKFLSVQ 268

HSP 2 Score: 65.855 bits (159), Expect = 2.127e-10
Identity = 63/265 (23.77%), Postives = 129/265 (48.68%), Query Frame = 3

Query: 2382 PVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDP-----YDVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEEL-EMEKLYNKERMKIKDFPPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKE---LLTKQLRIEQSMTSKSLFGKLFKEN 3149
            P++KMI  +   G + EG+FR  G++K+   ++  +    N++ +   DP     YDV+S LK +FR L++P++T   ++ +  A+   +  +K   +KE ++ LP  NY   R L+ L   I  +   T+M+  +L+ S  +      D +    + +I+  LI N+  LFD + +++ ++E+      +  +        ++R  YI P +           R S  KK +F  +    ++  + +++ +T K +  +LF ++
Sbjct:  502 PINKMISFIISRGLKSEGIFRICGTIKKVNILHKSIEKSGNNFFI---DPLIYNVYDVSSCLKKYFRSLDEPIITSNLFDIFRGALIEENQSRKITLYKEGLSFLPRDNYSVFRDLLELFYMIQMSVTDTRMDCSSLAIS-VSSSFISFDHINTEISSKIMKELIENFIALFDYSGKKINDLERFVAGPEIVAQ-------KIIRNFYIHPNINSVTI------RNSESKKLNFIDKDANFVSVIINVDEYVTVKQIIERLFTDS 749

[Close]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000075717.1 (SMESG000075717.1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.052e-12
Identity = 41/116 (35.34%), Postives = 64/116 (55.17%), Query Frame = 3

Query: 1053 IMHEINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDG---EQPEIDYR------FINDKYSRKRF 1373
            I + I   A N  C +C S D  WAS+NL I++C +CSG+HR++G ++S+++    DE + E+   I + Q IGN  AN  W A+      ++PE D        ++  KY +K F
Sbjct:  664 IANLIRSIAGNEVCCDCGSPDPCWASLNLGISVCIECSGVHRQLGTHLSRVRSFQLDEWSKEH---IAVMQAIGNTLANSVWEASVHASSLKKPEADSSRSDKEAWVRSKYEKKMF 776

The following BLAST results are available for this feature:

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARAP2	8.937e-35	29.75	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ARAP3	6.984e-29	26.55	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ARAP3	1.138e-28	26.52	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ARAP3	1.138e-28	26.52	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ARAP3	2.031e-28	27.27	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F23H11.4	3.141e-19	28.17	pep chromosome:WBcel235:III:902151:907539:-1 gene:...	[more]
cnt-2	5.875e-15	29.23	Arf-GAP with ANK repeat and PH domain-containing p...	[more]
cnt-2	7.321e-15	32.93	Arf-GAP with ANK repeat and PH domain-containing p...	[more]
cnt-2	7.759e-15	32.93	Arf-GAP with ANK repeat and PH domain-containing p...	[more]
cnt-2	8.058e-15	32.93	Arf-GAP with ANK repeat and PH domain-containing p...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RhoGAP15B	1.107e-14	29.08	gene:FBgn0030808 transcript:FBtr0110990	[more]
RhoGAP15B	1.116e-14	29.08	gene:FBgn0030808 transcript:FBtr0290096	[more]
CenB1A	4.621e-14	30.11	gene:FBgn0039056 transcript:FBtr0084369	[more]
CenB1A	8.356e-14	29.19	gene:FBgn0039056 transcript:FBtr0084368	[more]
CenG1A	1.514e-11	35.24	gene:FBgn0028509 transcript:FBtr0080548	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arap1a	5.491e-36	26.84	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
arap3	6.577e-30	26.39	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
CR387919.1	4.550e-29	25.65	zmp:0000000660 [Source:NCBI gene;Acc:559690]	[more]
CR387919.1	4.550e-29	25.65	zmp:0000000660 [Source:NCBI gene;Acc:559690]	[more]
FO704810.1	1.763e-24	25.14	arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccn4	2.935e-33	23.80	cellular communication network factor 4 [Source:Xe...	[more]
itgav	1.336e-22	27.10	integrin subunit alpha V [Source:Xenbase;Acc:XB-GE...	[more]
itgav	1.424e-22	27.10	integrin subunit alpha V [Source:Xenbase;Acc:XB-GE...	[more]
itgav	1.754e-22	27.10	integrin subunit alpha V [Source:Xenbase;Acc:XB-GE...	[more]
itgav	2.138e-22	27.10	integrin subunit alpha V [Source:Xenbase;Acc:XB-GE...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Arap2	6.849e-35	30.30	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
Arap3	1.869e-27	25.99	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
Arap3	2.080e-27	25.99	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
Arap1	9.350e-27	23.85	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
Arap1	9.966e-27	23.85	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8WZ64\|ARAP2_HUMAN	4.292e-34	29.75	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
sp\|Q8BZ05\|ARAP2_MOUSE	1.979e-33	30.03	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
sp\|Q8WWN8\|ARAP3_HUMAN	3.354e-28	26.55	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
sp\|Q8R5G7\|ARAP3_MOUSE	1.308e-26	25.99	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
sp\|Q96P48\|ARAP1_HUMAN	1.461e-26	24.36	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3L8SUZ2	5.848e-55	25.81	Uncharacterized protein (Fragment) OS=Chloebia gou...	[more]
A0A093QCG1	1.885e-54	25.56	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
H0ZFT5	4.097e-54	25.70	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
H0UZX6	1.380e-53	26.17	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
A0A0P6J175	1.965e-53	26.03	Arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARAP1	7.429e-33	26.33	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
arap3	3.452e-30	26.84	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
arap3	3.481e-30	26.84	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ENSAMXT00000019510.2	1.215e-27	26.36	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ENSAMXT00000000841.2	1.451e-24	29.34	arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000232.1	2.322e-24	22.91	pep scaffold:Pmarinus_7.0:GL480628:15362:26221:1 g...	[more]
ENSPMAT00000007633.1	3.594e-23	34.03	pep scaffold:Pmarinus_7.0:GL488501:137984:146551:-...	[more]
ENSPMAT00000003939.1	5.750e-18	31.54	pep scaffold:Pmarinus_7.0:GL477112:28457:91290:-1 ...	[more]
GIT2	1.875e-13	29.05	GIT ArfGAP 2 [Source:HGNC Symbol;Acc:HGNC:4273]	[more]
ENSPMAT00000000404.1	4.309e-13	29.79	pep scaffold:Pmarinus_7.0:GL476366:629540:661972:1...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
AGE2	1.154e-11	31.03	ADP-ribosylation factor (ARF) GTPase activating pr...	[more]
AGE1	1.245e-9	30.41	ADP-ribosylation factor (ARF) GTPase activating pr...	[more]
GLO3	5.332e-9	32.61	ADP-ribosylation factor GTPase activating protein ...	[more]
RGD1	2.343e-8	25.79	GTPase-activating protein (RhoGAP) for Rho3p and R...	[more]
RGA2	3.146e-8	30.69	GTPase-activating protein for polarity-establishme...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO34673	1.795e-26	30.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43007	2.519e-14	31.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34178	1.573e-13	28.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37809	5.021e-13	31.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33091	5.590e-13	32.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000045891.1	2.034e-30	27.46	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
arap3	2.895e-29	26.51	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
arap3	3.086e-29	26.51	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]
ENSORLT00000040486.1	1.734e-21	28.03	arf-GAP with Rho-GAP domain, ANK repeat and PH dom...	[more]
ARAP1	7.049e-18	31.28	ArfGAP with RhoGAP domain, ankyrin repeat and PH d...	[more]

BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000006535.1	0.000e+0	99.51	SMESG000006535.1	[more]
SMESG000070925.1	2.011e-29	25.98	SMESG000070925.1	[more]
SMESG000070668.1	4.719e-29	27.93	SMESG000070668.1	[more]
SMESG000070925.1	3.198e-26	31.44	SMESG000070925.1	[more]
SMESG000075717.1	1.052e-12	35.34	SMESG000075717.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30032591 ID=SMED30032591|Name=arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like|organism=Schmidtea mediterranea sexual|type=transcript|length=3812bp
TATATAAATCTTATATGAAATGGAATTTTTAAAAATTGTTTCGCTAATTA
TTTTTTGATTCCTTTGATATGTCAGATAATGAAAGAATACTAGAAACAAA
TTGGAAAATCGAAGATTTTGATCGAAATATTCCAAAACCCAAACCACCTC
CAAGAAATGGTTCTTTACGCACATATTTATCAGAAGAAGGTGACGATGTA
ATATCTGTATCGTGTAAAGATATCGAAGGAGAATCAGTCGATGATTTAGA
TTTACCAGATGATTTAGGAATGCCCGTATTCAGTCAGCCTTTAATGAAAA
ATTACGCTAAATCTCCTAATAAAACGATTAAATCCGATAATATTCCGTTT
CCAAAGCTTCCTTGTTTTTCAGAATTCGATGATAACGACAGATTAGAGTA
TCATGGACCGATAGTTCAAATTGTACAAAAATTAACATCTAGTAGAAAAT
CCAGGTACGCAGTGTTGATGTCTAACAAATTGATATTATTCGAAAAACCC
GAACACAAAGTGTCGAAAGTTCAAATCCCATTAAAATCTATGAAAGGCAT
CGATTGGGTGGATTCAGTCAATTGTTCCAATAAAGATGATTGCAATAAAT
TCAAACTTGAAACTCCCGTGAAATCATTCAAGTTCCAATGTTCTAGTCAC
GAAAACGCCGGGAAGTGGATTAATCACATTGGGAAACTTATTTATGATAA
ACAGCAGATCGATGAATCAGATAATTCTCATTTATTAAAAGCTTTGGTTT
CATTGGAAAATGTAAAAGGCAAGCGGATATTTACCATCGAACCGAAATTC
ACAATTGCCTATTATGATAACGATGAAGATTTCAAATACGGAATCGCTAT
GCATCGGATCCAATTGAGATCAAGCGGAGTGAAACGAGACGGGAACGACA
GCAATTCATTGTCATTGATTACGTCATATAGAAGATACAAATTAACATTT
GAAAGCATCAACCTGTGCAATGAATGGTTTCATCAGATAACCATCATAAT
CCAGAAAGCGATTTCCGCAACCTGTTCAAGAAATGCCAGGCCCGGTGAGG
ACATAATGCACGAGATTAACAAAAATGCCAGCAACCGATTTTGCGCCGAA
TGTAAATCGACCGACATCGAATGGGCGTCAGTAAATCTATTCATCACTTT
GTGTGCCAAATGTTCCGGGCTACATCGAAAAATGGGTCCGAACATCTCGA
AAATCCAAGGAATATTCACCGACGAATCGACTTGGGAAAATGGCAATCTC
ATCAGAATCTTTCAAATCATAGGCAACAACAACGCAAACAAATTCTGGTT
GGCTAATTTCGATGGGGAACAACCGGAAATCGATTATAGATTCATCAATG
ATAAATACAGCAGGAAGCGGTTCTCTGAGAGAAAGGAAACGATTTTCGAT
AAATACAAAGACAGCCAAGCTTTGAATAGAGAACTGATAGAATGCGTCAA
AACTGAAAACATCATACGAACGATGCAACTGTTTCACATTGGGGCTGATA
TGAACTACGTTTCGGAACCCAGTGGATTGAATTCTTTGGAAACTGCGGGG
AAATATCACCAAATGCTGCAATTGACTTATTTGAACTCTCAATGCAAATG
CCAAATCAGAGACTGGAGGAGTGATCTGTTCGACTCGATCGATCCAGACC
CTGACAACACCAAGCAAACGCCCTACCAGGGGAAATATTGGCTATCCATC
AACCAAAACCCAAAAGAATTCCGAATCATATTGATCTGGAAAAGCTGTAT
ACAGATTCTCGATTGTTCCAATAAAGAAGTATGCAAAATACTGTTTCGAA
ACATCTGTTTGATAAGAGAAAAACTCAACGAATCCGAAGGAATAAGCCTC
GTTATTGTTGTCCAGGAAACGGACTACTCAACGAAACCCGCGGATTATGT
CGAGTCCGGCATTAGTGTGATTGAGATTTCCAGTGCTGACCAATCGAACA
ACTTGCGAGATTTCAAAAATGCTATCGGTCAAAATCTGTCACCAAATTTC
GTGCCGAGTTTCTCGTACGCTTGTATCGGTTGGGTTATCTTGAGCACAGT
GAGTGAAGATTGGAAGCCTCATCTATTCACTATCGACTATTGTAGCATTG
CCAGCTTTTACGAGGTGAATGAGGGCCGAGAAAATCTGTGTATTGATTTG
AGAAAAGTAAACAAAATTGAAGAATTAAAGGACAGCAACTGCGAAAGCGT
CTGCCCGTATAAGATGTATAATCTTGCCTCTATTTGTTTGATATCATCGG
TTATCTATCATCTGAGAGGCGATACAAAAGAATCTCATGAAGAACTTCTT
AAAGCCTTTCTCCAGAGTTGGTATGTAAGAGATTCCACTTCGTTGTCCAA
TCAATTTCTCACCCAGAACAATGTTCCATTGCCTGTTTCAAAAATGATTA
GACACCTTCAATTGCACGGCACCCAAATTGAAGGCCTGTTTAGAAAGGTC
GGCAGTGTGAAAGAAGCGGAAAGAATATATGACCAGCTGATCTCCGATCC
GAATTCATATGTCCTAACCAACAGTGATCCCTATGACGTAGCCAGCGCTT
TGAAGCTATTCTTTCGTAAATTAGAAGATCCATTGCTGACGAAATTGTAC
TATGAAAACTGGATTGCAGCTGTTGACATTAGGGATTCCGAGAAAAAGTT
CGAATATTTCAAAGAAATAATCAATAAACTCCCGGTAATCAATTACCAAA
CACTGAGGCTGTTGATTTTTCTACTCGTAAACATCGACAAGAATAATGAC
GTCACCCAAATGAACCCGGACAATTTGTCCACCAGTTTCAACACTTGCCT
CATATCTGGATCTGATCAGATGTTCAATGCGAAAAATCTGCAAATTTTGC
CCTATCTAATAAGAAACTACCAGGATCTGTTTGATGTAACCCAGGAAGAG
CTGGAAATGGAAAAACTCTACAACAAAGAACGAATGAAAATAAAGGACTT
CCCGCCATTGGAAATCAGCCTACTGAGACAGATTTATATTTTACCGGAAC
TGGAAAGATTTCTCAAACCGGATATTAATTTCGAAAGGGAATCTGGACAT
AAAAAAACCGATTTCTTTAAAGAACTTCTAACGAAACAGTTACGCATTGA
ACAATCGATGACTTCAAAATCTCTATTTGGAAAGCTGTTCAAAGAAAACA
CAAATACTCAGAATATCTCCATTTTCGAGGATCGAAAAGTTGACGATTTC
CACATGGAACATCTAGTATATCCGGACGAGAACCTGATTGAGGTTATACA
AAATTCGGAAAAATGCGATGTTCCCAGTAAATGGATATTTAAAATCAACA
AATATACACTGGATGCCGATTCGACAAGTAAATCGTTTCAATGTCAAGCG
TCATTGTCGATGTCGAGCAAAAATAGAGTCATCATTGAATTGACAGAAAA
ACATGAATTAATTATCTGTAGAAACGATCAAACTCAGGATTTAATCATTA
AAATTAAAGACTTGATTCTTTTTAGAAGTTGTGAGGATAATAAAAATTTT
GTGGCTTTCGAATACCGAAAAAACCAAAGCAGTACTATGCCCAGTGTGTT
GCAGATATTTTCATTCAGATCACGATCTTCTTTTAATATTATTCATTTCT
CAAACGAAACCGATTATTTTAATTTCCTAAAGCACTACGACAGATTTAAA
TTGGTGGAAATAAAGTATCCCGAAAGCCGTAGCCAATTAACTGCATCCAC
AGTTATATAAACTGATTAATTTTATATTTTTACTTTTCAATATTTGCTCA
AATGTTTTTTAAATAATATTTAGAGATTTTATATGAAATTCCATTTTAAA
AGTTGATTTGTA

protein sequence of SMED30032591-orf-1

>SMED30032591-orf-1 ID=SMED30032591-orf-1|Name=SMED30032591-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1214bp
MSDNERILETNWKIEDFDRNIPKPKPPPRNGSLRTYLSEEGDDVISVSCK
DIEGESVDDLDLPDDLGMPVFSQPLMKNYAKSPNKTIKSDNIPFPKLPCF
SEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSK
VQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKW
INHIGKLIYDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYD
NDEDFKYGIAMHRIQLRSSGVKRDGNDSNSLSLITSYRRYKLTFESINLC
NEWFHQITIIIQKAISATCSRNARPGEDIMHEINKNASNRFCAECKSTDI
EWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQI
IGNNNANKFWLANFDGEQPEIDYRFINDKYSRKRFSERKETIFDKYKDSQ
ALNRELIECVKTENIIRTMQLFHIGADMNYVSEPSGLNSLETAGKYHQML
QLTYLNSQCKCQIRDWRSDLFDSIDPDPDNTKQTPYQGKYWLSINQNPKE
FRIILIWKSCIQILDCSNKEVCKILFRNICLIREKLNESEGISLVIVVQE
TDYSTKPADYVESGISVIEISSADQSNNLRDFKNAIGQNLSPNFVPSFSY
ACIGWVILSTVSEDWKPHLFTIDYCSIASFYEVNEGRENLCIDLRKVNKI
EELKDSNCESVCPYKMYNLASICLISSVIYHLRGDTKESHEELLKAFLQS
WYVRDSTSLSNQFLTQNNVPLPVSKMIRHLQLHGTQIEGLFRKVGSVKEA
ERIYDQLISDPNSYVLTNSDPYDVASALKLFFRKLEDPLLTKLYYENWIA
AVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNP
DNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVTQEELEMEKL
YNKERMKIKDFPPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFF
KELLTKQLRIEQSMTSKSLFGKLFKENTNTQNISIFEDRKVDDFHMEHLV
YPDENLIEVIQNSEKCDVPSKWIFKINKYTLDADSTSKSFQCQASLSMSS
KNRVIIELTEKHELIICRNDQTQDLIIKIKDLILFRSCEDNKNFVAFEYR
KNQSSTMPSVLQIFSFRSRSSFNIIHFSNETDYFNFLKHYDRFKLVEIKY
PESRSQLTASTVI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0005096	GTPase activator activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR038508	ArfGAP_dom_sf
IPR037278	ARFGAP/RecO
IPR001164	ArfGAP_dom
IPR001849	PH_domain
IPR000198	RhoGAP_dom
IPR011993	PH-like_dom_sf
IPR008936	Rho_GTPase_activation_prot

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction
GO:0043547	positive regulation of GTPase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001164	Arf GTPase activating protein	SMART	SM00105	arf_gap_3	coord: 327..443 e-value: 1.9E-19 score: 80.6
IPR001164	Arf GTPase activating protein	PFAM	PF01412	ArfGap	coord: 329..450 e-value: 3.3E-24 score: 85.2
IPR001164	Arf GTPase activating protein	PROSITE	PS50115	ARFGAP	coord: 327..443 score: 19.592
IPR000198	Rho GTPase-activating protein domain	SMART	SM00324	RhoGAP_3	coord: 767..936 e-value: 1.2E-37 score: 141.1
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 770..915 e-value: 4.8E-36 score: 123.9
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 757..938 score: 34.752
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 224..314 e-value: 7.5 score: 13.9 coord: 109..211 e-value: 2.1E-10 score: 50.6
IPR001849	Pleckstrin homology domain	PFAM	PF00169	PH	coord: 110..208 e-value: 6.6E-8 score: 33.0
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 108..209 score: 8.92
IPR011993	PH-like domain superfamily	GENE3D	G3DSA:2.30.29.30		coord: 106..221 e-value: 2.2E-10 score: 42.3
IPR011993	PH-like domain superfamily	GENE3D	G3DSA:2.30.29.30		coord: 222..318 e-value: 1.2E-5 score: 26.9
IPR038508	ArfGAP domain superfamily	GENE3D	G3DSA:3.30.40.160		coord: 319..443 e-value: 1.5E-27 score: 98.0
IPR008936	Rho GTPase activation protein	GENE3D	G3DSA:1.10.555.10		coord: 750..950 e-value: 3.7E-46 score: 158.6
IPR008936	Rho GTPase activation protein	SUPERFAMILY	SSF48350	GTPase activation domain, GAP	coord: 766..941
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 16..36
None	No IPR available	PANTHER	PTHR45899	FAMILY NOT NAMED	coord: 127..979
None	No IPR available	CDD	cd08837	ArfGap_ARAP	coord: 332..436 e-value: 1.22307E-30 score: 115.166
None	No IPR available	CDD	cd00821	PH	coord: 111..204 e-value: 6.58658E-7 score: 46.3818
None	No IPR available	SUPERFAMILY	SSF50729	PH domain-like	coord: 111..215
None	No IPR available	SUPERFAMILY	SSF50729	PH domain-like	coord: 235..314
IPR037278	ARFGAP/RecO-like zinc finger	SUPERFAMILY	SSF57863	ArfGap/RecO-like zinc finger	coord: 328..437