Peptidase S1 domain-containing protein

Overview
NamePeptidase S1 domain-containing protein
Smed IDSMED30032570
Length (bp)714
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032570

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30032570h1SMcG0008007 SmedASXL_011083SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30032570h1SMcG0008007 SmedASXL_011083SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pigment cellSMED30032570h1SMcG0008007 SmedASXL_011083SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017
whole organism asexual adult RNA-sequencing evidence
neoblastSMED30032570h1SMcG0008007 dd_Smed_v4_10973_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30032570h1SMcG0008007 dd_Smed_v6_10973_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30032570h1SMcG0008007 OX_Smed_1.0.17359ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CELA1 (chymotrypsin like elastase 1 [Source:HGNC Symbol;Acc:HGNC:3308])

HSP 1 Score: 53.5286 bits (127), Expect = 6.158e-8
Identity = 32/119 (26.89%), Postives = 55/119 (46.22%), Query Frame = 1
Query:   34 LTEASKRVLNGEFSETNQFPFSAYLGH---------CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ 363
            L E + RV+ G  +  N +P    L +         C G++I  + ++TAAHCV ++   T  V+ G       + + +Y  + KI +HP +        YD+A+L    S+  N  +Q
Sbjct:   12 LPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQ--KTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQ 128          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS11D (transmembrane serine protease 11D [Source:HGNC Symbol;Acc:HGNC:24059])

HSP 1 Score: 53.5286 bits (127), Expect = 8.618e-8
Identity = 40/142 (28.17%), Postives = 64/142 (45.07%), Query Frame = 1
Query:   34 LTEASKRVLNGEFSETNQFPFSAYLG-----HCSGSIISAHAILTAAHCVCHETNATLHVLV-GSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAV--NYSCQRLEKGQVTIFIGYGSDE 435
            +T + +R+L G  +E   +P+   L      HC GS+I+   ILTAAHC    +N    +   G    +PK        +  I IH  YK   +    D+A++  + S+ F K I +V    + Q +  G      G+G+ E
Sbjct:  180 ITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPK----LRMRVRNILIHNNYKSATHEN--DIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQE 315          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 52.373 bits (124), Expect = 2.338e-7
Identity = 65/242 (26.86%), Postives = 101/242 (41.74%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCH---ETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNY--SCQRLEKGQVTIFIGYGSDENENDG--ILKYGTA------------VIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIG---GKSDNYTIGV--PIYSFCDWLLNNV*R 675
            S R++ G  S  +Q+P+ A L       C GS+I+   I+TAAHCV       + T+ V + S +  P       + ++KI  H  YK        D+A++     L FN+ IQ V    S +    G+V    G+G+ E+  D   +L +               V G      M  +    G  D   GDSG P+V ++   +  VG      G ++    GV   + SF DW+   + R
Sbjct:  212 SSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNP----APSHLVEKIVYHSKYKP--KRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMER 447          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 52.373 bits (124), Expect = 2.791e-7
Identity = 65/242 (26.86%), Postives = 101/242 (41.74%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCH---ETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNY--SCQRLEKGQVTIFIGYGSDENENDG--ILKYGTA------------VIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIG---GKSDNYTIGV--PIYSFCDWLLNNV*R 675
            S R++ G  S  +Q+P+ A L       C GS+I+   I+TAAHCV       + T+ V + S +  P       + ++KI  H  YK        D+A++     L FN+ IQ V    S +    G+V    G+G+ E+  D   +L +               V G      M  +    G  D   GDSG P+V ++   +  VG      G ++    GV   + SF DW+   + R
Sbjct:  214 SSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNP----APSHLVEKIVYHSKYKP--KRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMER 449          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 52.373 bits (124), Expect = 2.791e-7
Identity = 65/242 (26.86%), Postives = 101/242 (41.74%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCH---ETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNY--SCQRLEKGQVTIFIGYGSDENENDG--ILKYGTA------------VIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIG---GKSDNYTIGV--PIYSFCDWLLNNV*R 675
            S R++ G  S  +Q+P+ A L       C GS+I+   I+TAAHCV       + T+ V + S +  P       + ++KI  H  YK        D+A++     L FN+ IQ V    S +    G+V    G+G+ E+  D   +L +               V G      M  +    G  D   GDSG P+V ++   +  VG      G ++    GV   + SF DW+   + R
Sbjct:  214 SSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNP----APSHLVEKIVYHSKYKP--KRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMER 449          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-1 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q23528])

HSP 1 Score: 54.6842 bits (130), Expect = 1.127e-8
Identity = 33/132 (25.00%), Postives = 64/132 (48.48%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFS----AYLGH--CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGS 429
            R++ G  S  + +P++    + LGH  C GS+I  + +LTAAHC   +   T + +   ++G  +  SG  + +  + IHP Y   G+   YD AI+     +  + + + +        + ++ +  G+GS
Sbjct:   57 RLIGGSESSPHSWPWTVQLLSRLGHHRCGGSLIDPNFVLTAAHCFAKDRRPTSYSV---RVGGHRSGSGSPHRVTAVSIHPWY-NIGFPSSYDFAIMRIHPPVNTSTTARPICLPSLPAVENRLCVVTGWGS 184          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 50.447 bits (119), Expect = 5.542e-7
Identity = 53/209 (25.36%), Postives = 91/209 (43.54%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLG-------HCSGSIISAHAILTAAHCVCH-ETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLS-LEFNKSIQAVNYSCQRL--EKGQVTIFIGYGSDENENDGILKYG-TAVIGNFD-----EAFMYLSRKRFGSG---------DGDSGAPIVIKKNN-TFIQVGLI 597
            RV+ G  +    FP++A L        HC  SI+    ++TAAHC    E  ++  V+VG       + + + + + +I  +PLYK    +  +D+AIL      +EFN+  Q +    +      G+  +  G+GS        L+     +I  FD     + +  +SR  F +G          GDSG P   ++ +  F+  G+I
Sbjct:  712 RVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKD---IFSHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGSMGLRYAERLQAALIPIINRFDCVNSSQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVI 917          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: l(2)k05911 (gene:FBgn0284244 transcript:FBtr0305556)

HSP 1 Score: 66.2402 bits (160), Expect = 2.629e-12
Identity = 68/250 (27.20%), Postives = 103/250 (41.20%), Query Frame = 1
Query:   31 ALTEASKRVLNGEFSETNQFPFSAYL-----GHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKI--KIHPLYKKCGY---LKPYDVAILYTKLSLEFNKSIQAV----NYSCQ-RLEKGQVTIFIGYGS--DENENDGIL---------------KYGTAVIGNFDEAFMYLSRKRFGSGDGDSGAPIVIKKNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWLLNNV 669
             +T   +R++ G  +  ++FP+ A L       C GS+I+   ILTAAHCV   T+  +  L      Y     G  +E+  +  +I  L +  G+       DVAIL     + F + IQ +    + S Q R   GQV    G+GS  +      IL               KYG A  G   E+ +   +    S  GDSG P+VI     + QVG++      GK     +   + S   W+  N+
Sbjct:  392 PVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMTSWDVAALTAHLGDY---NIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGIIESMICAGQAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNI 638          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG7542 (gene:FBgn0036738 transcript:FBtr0345386)

HSP 1 Score: 62.003 bits (149), Expect = 4.107e-11
Identity = 67/250 (26.80%), Postives = 108/250 (43.20%), Query Frame = 1
Query:   34 LTEASKRVLNGEFSETNQFPFSAYLG--------HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDK--IKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIF-------IGYGSDENENDG---ILKYGTAVI-----------GNFDEAFMYLSRKRFGSG-DGDSGAPIVIKKNNTFIQVGLIG-GKSDNYTIGVP-----IYSFCDWLLNNV 669
            LT+    + NGE +E  QFP+ A L          C G++IS + I+TAAHC+    + T++ L    IG   E   +   ++K  I +H  Y     +   D++++     + F   I+A   S  R   GQ   +        G+G + + +D    +L+Y    I           G   E  + +S     S   GDSG P+V K+ N+   +G    G S    +G P     I S+ DW+LN++
Sbjct:   20 LTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESVTVY-LGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVN--DISLIRLPAFVGFTDRIRAA--SLPRRLNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSGAVSEKMICMSTTSGKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISSYLDWILNHI 264          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG7542 (gene:FBgn0036738 transcript:FBtr0075181)

HSP 1 Score: 62.003 bits (149), Expect = 4.107e-11
Identity = 67/250 (26.80%), Postives = 108/250 (43.20%), Query Frame = 1
Query:   34 LTEASKRVLNGEFSETNQFPFSAYLG--------HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDK--IKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIF-------IGYGSDENENDG---ILKYGTAVI-----------GNFDEAFMYLSRKRFGSG-DGDSGAPIVIKKNNTFIQVGLIG-GKSDNYTIGVP-----IYSFCDWLLNNV 669
            LT+    + NGE +E  QFP+ A L          C G++IS + I+TAAHC+    + T++ L    IG   E   +   ++K  I +H  Y     +   D++++     + F   I+A   S  R   GQ   +        G+G + + +D    +L+Y    I           G   E  + +S     S   GDSG P+V K+ N+   +G    G S    +G P     I S+ DW+LN++
Sbjct:   20 LTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESVTVY-LGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVN--DISLIRLPAFVGFTDRIRAA--SLPRRLNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSGAVSEKMICMSTTSGKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISSYLDWILNHI 264          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG30087 (gene:FBgn0050087 transcript:FBtr0100573)

HSP 1 Score: 61.6178 bits (148), Expect = 5.410e-11
Identity = 62/241 (25.73%), Postives = 105/241 (43.57%), Query Frame = 1
Query:   37 TEASKRVLNGEFSETNQFPFSAY-----LGHCSGSIISAHAILTAAHCVCHETNATLHVLVGS-KIGYPKEMSG-------KYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILK-YGTAVIGNFDEAFMYLSRKRFGSGD-------------GDSGAPIVIKKN----NTFIQVGLIG-GKSDNYTIGVPIY--SFCDWL 657
            ++ + RV+NG+ +     PF  Y     L HC GSI+++  ILTAAHCV       L + +G   I    +  G       + Y I K   H  Y    ++   D+A+L    S+ FN  IQ +           V  +  +G  E + +G      TA +  +D A+   S   + +G+             GDSG P+V + +      ++Q+G++  G +D  + GV  Y  ++ +W+
Sbjct:   36 SQTAMRVVNGKEAVIRSAPFMVYVTNNSLTHCGGSILNSRYILTAAHCVF----PNLRLRLGEHNIRTDPDCQGSNCSPRSEEYGIMKAITHRFYNAANHVN--DIALLKLNRSINFNVHIQPICILLNPASAPSVATYQTFGWGETKKNGFPHLLQTAELRAYDAAYCSRSFHAYMNGNQICAGHEERDTCAGDSGGPLVTRVDFDGVKRYLQLGIVSYGPTDCQSPGVYTYVPNYINWI 270          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG31265 (gene:FBgn0051265 transcript:FBtr0083402)

HSP 1 Score: 58.5362 bits (140), Expect = 5.543e-10
Identity = 59/234 (25.21%), Postives = 101/234 (43.16%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLG------HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPY---DVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSD-----ENENDGILKYGTAVIGNFDEAF-----------MYLSRKRFGSGDGDSGAPIVIKKNNTFIQVGLIGGKSDNYTIGVP-----IYSFCDWL 657
            S R+  GE +E    P+   L       +C G+I++ + I+TA HCV +   A ++V+ G+      E    YY  +      ++K C Y +PY   D+A++    ++ FN+  Q +    + ++ G+  +  G+GSD       E+   L  G   +    E F              SR+  G+  GDSG P+V   N   + V   G       +G+P     +Y + DW+
Sbjct:   34 SGRIKGGEEAEIGFAPYQVSLQPIVGSHNCGGAILNENWIITAGHCVENFIPALVNVITGTNKW--AEPGAIYYTAE------IHKHCMYDQPYMHNDIALVKLTENITFNELTQPIALPTRPVQLGEEIVLTGWGSDVAYGSSMEDLHKLTVGLVPLDECYETFNRTSSMGVGHICTFSREGEGACHGDSGGPLV--SNGQLVGVVNWGRPCG---VGLPDVQANVYYYLDWI 254          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: f7l (coagulation factor VII, like [Source:ZFIN;Acc:ZDB-GENE-070424-102])

HSP 1 Score: 65.4698 bits (158), Expect = 6.642e-12
Identity = 55/247 (22.27%), Postives = 98/247 (39.68%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCG--------------YLKPYDVAILYTKLSLEFNKSIQAVNYSC-----------------QRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGDGDSGAPIVIKKNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWLLNNV 669
            R++ G+     Q P+ A L +     C G I+++  I+TAAHC+  +  A L V+VG  I    E + +  ++ ++ +HP Y                   L PY + +     +  F++++ ++  S                  QRL+  +V+       D     G+      +   F E           S  GDSG P+V +  NT+   G++       ++D Y I   +  F +W+L  V
Sbjct:  194 RIVKGDVCPKGQCPWQALLEYDGQYKCGGVILNSQWIITAAHCIWRKDPALLQVIVGEHIRDRDEGTEQMRKVSEVFLHPQYNHSSTDSDVALLRLHRPVTLGPYALPVCLPPPNGTFSRTLASIRMSTVSGWGRLAQSGPPSTVLQRLQVPRVS-----SEDCRARSGLTVSRNMLCAGFAEGGR-------DSCQGDSGGPLVTRYRNTWFLTGIVSWGKGCARADVYGIYTRVSVFVEWILKTV 428          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.6 (chymotrypsin like elastase family member 1, tandem duplicate 6 [Source:ZFIN;Acc:ZDB-GENE-040808-55])

HSP 1 Score: 62.7734 bits (151), Expect = 2.574e-11
Identity = 39/139 (28.06%), Postives = 65/139 (46.76%), Query Frame = 1
Query:   43 ASKRVLNGEFSETNQFPFS---------AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ--AVNYSCQRLEKGQVTIFIGYG 426
            A +RV+ GE +  N +P+          +Y   C G++I  + +LTAAHCV  +T+ T  V++G    Y +E   +Y  +  + IHP + +      YD+A+L    +   N  +Q   +  S Q L         G+G
Sbjct:   26 AQERVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGTLIKQNFVLTAAHCV--DTSRTWRVVLGEHDIYKQEGREQYMTVSNVYIHPNWNRNNVAAGYDIALLRLSSNASLNTYVQLGTLPPSGQVLPHNNACYITGWG 162          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.6 (chymotrypsin like elastase family member 1, tandem duplicate 6 [Source:ZFIN;Acc:ZDB-GENE-040808-55])

HSP 1 Score: 62.7734 bits (151), Expect = 2.684e-11
Identity = 39/139 (28.06%), Postives = 65/139 (46.76%), Query Frame = 1
Query:   43 ASKRVLNGEFSETNQFPFS---------AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ--AVNYSCQRLEKGQVTIFIGYG 426
            A +RV+ GE +  N +P+          +Y   C G++I  + +LTAAHCV  +T+ T  V++G    Y +E   +Y  +  + IHP + +      YD+A+L    +   N  +Q   +  S Q L         G+G
Sbjct:   26 AQERVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGTLIKQNFVLTAAHCV--DTSRTWRVVLGEHDIYKQEGREQYMTVSNVYIHPNWNRNNVAAGYDIALLRLSSNASLNTYVQLGTLPPSGQVLPHNNACYITGWG 162          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: prss60.1 (serine protease 60.1 [Source:ZFIN;Acc:ZDB-GENE-070424-25])

HSP 1 Score: 60.077 bits (144), Expect = 3.180e-10
Identity = 62/244 (25.41%), Postives = 103/244 (42.21%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYL------GH-CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDK----IKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQR--LEKGQVTIFIGYGSDE----NENDGILKYGTAVIGNFDEAFMYLSRKRF-----------GSGD---GDSGAPIVIKKNNTFIQVGLIG---GKSDNYTIGV 630
            + L L V    L   + R++ G  +    +P+   L      GH C GS+I++  +LTAAHC+   T ++L V +G       +     YEI++    I +HP Y         D+A+L+   ++ F+  I+ V  + Q      G  +   G+G+ +        GIL+     +   D+    L                G  D   GDSG P+V K+   ++Q G+     G +D Y+ GV
Sbjct:    9 LALLLCVQVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLVFLGKT----TQQGVNTYEINRTVSVITVHPSYNN--LTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGV 246          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.3 (chymotrypsin like elastase family member 1, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-040801-12])

HSP 1 Score: 59.3066 bits (142), Expect = 4.046e-10
Identity = 40/148 (27.03%), Postives = 65/148 (43.92%), Query Frame = 1
Query:   25 FLALTEASKRVLNGEFSETNQFPF---------SAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ--AVNYSCQRLEKGQVTIFIGYGSDE 435
            +L   +   RV+ GE ++ N +P+         S+Y   C GS+I    ++TAAHCV  ++  T  V++G    Y  E   +Y  + +  IHP +        YD+A+L        N  +Q  A+  S Q L         G+G  +
Sbjct:   20 YLEDIDIEGRVVGGEVAKPNSWPWQISLQYLSGSSYYHTCGGSLIRPGWVMTAAHCV--DSPRTWRVVLGDHDIYNHEGREQYISVSRAHIHPNWNSNSLSSGYDIALLELSSDASLNSYVQLAALPPSGQVLPNNNPCYISGWGRTQ 165          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: tenm2 (teneurin transmembrane protein 2 [Source:Xenbase;Acc:XB-GENE-5799894])

HSP 1 Score: 72.7886 bits (177), Expect = 2.755e-14
Identity = 58/211 (27.49%), Postives = 93/211 (44.08%), Query Frame = 1
Query:   37 TEASKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNAT--LHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEF--NKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGILKYGTAVI---GNFDEAFMY------------LSRKRFGSGDGDSGAPIVIKKNNTFIQVG 591
            T    R++ G  +    +P+   L +     C GS+I+A+ I+TAAHCV  +T++       +G KI  P       Y +D+I +HP Y         D+A++  K S+ F  N+ +   NY  Q  E+GQ     G+G+   +     +LKY    +      ++  MY              +    S  GDSG P+V K N+ +  VG
Sbjct:  145 TYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSLWKAFIG-KIKMPSYYDSSAYSVDRIIVHPDYSS--QTNSNDIALMKLKTSIAFSSNRPVCLPNYGMQ-WEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVG 351          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: tenm2 (teneurin transmembrane protein 2 [Source:Xenbase;Acc:XB-GENE-5799894])

HSP 1 Score: 72.0182 bits (175), Expect = 5.077e-14
Identity = 58/210 (27.62%), Postives = 93/210 (44.29%), Query Frame = 1
Query:   37 TEASKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNAT--LHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEF-NKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGILKYGTAVI---GNFDEAFMY------------LSRKRFGSGDGDSGAPIVIKKNNTFIQVG 591
            T    R++ G  +    +P+   L +     C GS+I+A+ I+TAAHCV  +T++       +G KI  P       Y +D+I +HP Y         D+A++  K S+ F +K +   NY  Q  E+GQ     G+G+   +     +LKY    +      ++  MY              +    S  GDSG P+V K N+ +  VG
Sbjct:  143 TYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSLWKAFIG-KIKMPSYYDSSAYSVDRIIVHPDYSS--QTNSNDIALMKLKTSIAFSSKPVCLPNYGMQ-WEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVG 348          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: tenm2 (teneurin transmembrane protein 2 [Source:Xenbase;Acc:XB-GENE-5799894])

HSP 1 Score: 70.8626 bits (172), Expect = 1.176e-13
Identity = 57/211 (27.01%), Postives = 93/211 (44.08%), Query Frame = 1
Query:   37 TEASKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNAT--LHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEF--NKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGILKYGTAVI---GNFDEAFMY------------LSRKRFGSGDGDSGAPIVIKKNNTFIQVG 591
            T    R++ G  +    +P+   L +     C GS+I+A+ I+TAAHCV  +T++       +G KI  P       Y +D+I +HP Y         D+A++  K S+ F  ++ +   NY  Q  E+GQ     G+G+   +     +LKY    +      ++  MY              +    S  GDSG P+V K N+ +  VG
Sbjct:  122 TYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSLWKAFIG-KIKMPSYYDSSAYSVDRIIVHPDYSS--QTNSNDIALMKLKTSIAFSISRPVCLPNYGMQ-WEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVG 328          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000027919.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:6533149:6542218:1 gene:ENSXETG00000016905.1 transcript:ENSXETT00000027919.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 7.816e-11
Identity = 62/230 (26.96%), Postives = 94/230 (40.87%), Query Frame = 1
Query:   37 TEASKRVLNGEFSETNQFPFS--------AYLGHCSGSIISAHAILTAAHCV--CHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC-----QRLEKGQVTIFIGYGSDENEND----------GILKYGT----AVIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIGGKSDNYTIGV 630
            T+   R++ G  +    +P+         A L  C GSII+ H ++TAAHCV     T +   V  GS        +G  Y +++  +HP Y    Y + YDVA+L    +L F  +++ V   C         +GQ     G+G+  N              ++   T    AV G      M  +    G  D   GDSG P+V K N+ +    L+G  S  Y  G+
Sbjct:  165 TKVDSRIVGGTVASAGDWPWQVQLLKRVGASLYLCGGSIITQHWVVTAAHCVYGSTSTPSAFKVFAGSLTIQSYYSAG--YTVERALVHPSYSS--YTQNYDVALLKLTAALVFTTNLRPV---CLPNVGMPWAEGQPCWISGWGTTSNGGSISTNLKAASVPLISSATCNQAAVYGGAISPTMMCAGYLSGGTDTCQGDSGGPLVTKTNSLWW---LVGDTSWGYGCGM 384          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046747.1 (chymotrypsin like elastase 1, gene 3 [Source:NCBI gene;Acc:101730694])

HSP 1 Score: 60.077 bits (144), Expect = 3.186e-10
Identity = 40/145 (27.59%), Postives = 64/145 (44.14%), Query Frame = 1
Query:   40 EASKRVLNGEFSETNQFPFSAYLGH---------CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQR--LEKGQVTIFIGYGSDENE 441
            E ++RV+ G     N +P+   L +         C GS+I A+ +LTAAHCV  +T  +  V+VG    Y  + + +Y  + +I  H  + +      YD+A+L+   S   N  +Q  N       L      I  G+G   N 
Sbjct:   24 EDNQRVIGGSEVARNSWPWQISLQYLSGGSWYHTCGGSLIRANRVLTAAHCV--DTVTSYRVVVGDHNIYQNDGTEQYISVSRIVQHANWNRNNVAAGYDIAVLHLASSAALNSYVQLANLPADGAVLAHNYACIITGWGKTSNN 166          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Masp1 (mannan-binding lectin serine peptidase 1 [Source:MGI Symbol;Acc:MGI:88492])

HSP 1 Score: 59.6918 bits (143), Expect = 6.001e-10
Identity = 57/247 (23.08%), Postives = 105/247 (42.51%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH------CSGSIISAHAILTAAHCVCHET----NATLH-----------VLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSD--ENENDGILKYGTAVIGN--FDEAFMYLSRK----------RFGSGD---GDSGAPIVIK--KNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWL 657
            R+ NG  ++    P+ A L H      C GS++ ++ +LTAAHC+ H++      TLH           +++G       +   ++  + +  +HPLY    +    D+ ++    S   N  +  V    Q   +G + I  G+G    +   + +++    ++ +    EA+  L +K          + G  D   GDSG P+V K  + + +  VG++      GK D Y +   IY   DW+
Sbjct:  453 RIFNGRPAQKGTMPWIAMLSHLNGQPFCGGSLLGSNWVLTAAHCL-HQSLDPEEPTLHSSYLLSPSDFKIIMGKHWRRRSDEDEQHLHVKRTTLHPLYNPSTFEN--DLGLVELSESPRLNDFVMPVCLPEQPSTEGTMVIVSGWGKQFLQRFPENLMEIEIPIVNSDTCQEAYTPLKKKVTKDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWI 696          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Prss38 (protease, serine 38 [Source:MGI Symbol;Acc:MGI:2685095])

HSP 1 Score: 57.3806 bits (137), Expect = 2.637e-9
Identity = 55/215 (25.58%), Postives = 96/215 (44.65%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCH-ETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHP---LYKKCGYLKPYDVAILYTKLSLEFN----------KSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFD-------------EAFMYLSRKRFGS-GDGDSGAPIVIKKNNTFIQVGLI 597
            ++L GEF+   ++P+   L +     C GSI+SA+ +L+AAHC    +   T  + VG           +++EI ++ IHP   +Y   G     DVA++  K ++ F+            +  +N SC     G ++     G   NE   +L+    +I  F              E       K   +  +GDSG+P+V K+N T++Q+G++
Sbjct:   55 KLLGGEFARDRKWPWQVSLHYSGFHICGGSILSAYWVLSAAHCFDRGKKLETYDIYVGITNLEKANRHTQWFEIYQVIIHPTFQMYHPIGG----DVALVQLKSAIVFSDFVLPICLPPSDLYLINLSCWTTGWGMIS---PQGETGNE---LLEAQLPLIPRFQCQLLYGLSSYLLPEMLCAADIKTMKNVCEGDSGSPLVCKQNQTWLQIGIV 259          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk6 (kallikrein related-peptidase 6 [Source:MGI Symbol;Acc:MGI:1343166])

HSP 1 Score: 56.6102 bits (135), Expect = 3.417e-9
Identity = 52/205 (25.37%), Postives = 87/205 (42.44%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYL---GH--CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGIL----------KYGTAVIGNFDEAFMYLSRKRFG--SGDGDSGAPIV 558
            + L L++   A +E  ++V++G     +  PF A L   GH  C G +I    +LTAAHC        L V++G       E   +   +D+  +HP Y         D+ +++ K  ++F+K IQ +       E+      +G+G  EN +  D I           +   A  G   ++ +     + G  S  GDSG P+V
Sbjct:   11 LALCLVLAKSAWSEEQEKVVHGGPCLKDSHPFQAALYTSGHLLCGGVLIDPQWVLTAAHC----KKPNLQVILGKHNLRQTETFQRQISVDRTIVHPRYNP--ETHDNDIMMVHLKNPVKFSKKIQPLPLKNDCSEENPNCQILGWGKMENGDFPDTIQCADVHLVPREQCERAYPGKITQSMVCAGDMKEGNDSCQGDSGGPLV 209          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk6 (kallikrein related-peptidase 6 [Source:MGI Symbol;Acc:MGI:1343166])

HSP 1 Score: 56.6102 bits (135), Expect = 3.417e-9
Identity = 52/205 (25.37%), Postives = 87/205 (42.44%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYL---GH--CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGIL----------KYGTAVIGNFDEAFMYLSRKRFG--SGDGDSGAPIV 558
            + L L++   A +E  ++V++G     +  PF A L   GH  C G +I    +LTAAHC        L V++G       E   +   +D+  +HP Y         D+ +++ K  ++F+K IQ +       E+      +G+G  EN +  D I           +   A  G   ++ +     + G  S  GDSG P+V
Sbjct:   11 LALCLVLAKSAWSEEQEKVVHGGPCLKDSHPFQAALYTSGHLLCGGVLIDPQWVLTAAHC----KKPNLQVILGKHNLRQTETFQRQISVDRTIVHPRYNP--ETHDNDIMMVHLKNPVKFSKKIQPLPLKNDCSEENPNCQILGWGKMENGDFPDTIQCADVHLVPREQCERAYPGKITQSMVCAGDMKEGNDSCQGDSGGPLV 209          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk6 (kallikrein related-peptidase 6 [Source:MGI Symbol;Acc:MGI:1343166])

HSP 1 Score: 56.6102 bits (135), Expect = 3.417e-9
Identity = 52/205 (25.37%), Postives = 87/205 (42.44%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYL---GH--CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENEN--DGIL----------KYGTAVIGNFDEAFMYLSRKRFG--SGDGDSGAPIV 558
            + L L++   A +E  ++V++G     +  PF A L   GH  C G +I    +LTAAHC        L V++G       E   +   +D+  +HP Y         D+ +++ K  ++F+K IQ +       E+      +G+G  EN +  D I           +   A  G   ++ +     + G  S  GDSG P+V
Sbjct:   11 LALCLVLAKSAWSEEQEKVVHGGPCLKDSHPFQAALYTSGHLLCGGVLIDPQWVLTAAHC----KKPNLQVILGKHNLRQTETFQRQISVDRTIVHPRYNP--ETHDNDIMMVHLKNPVKFSKKIQPLPLKNDCSEENPNCQILGWGKMENGDFPDTIQCADVHLVPREQCERAYPGKITQSMVCAGDMKEGNDSCQGDSGGPLV 209          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P35048|TRYP_SIMVI (Trypsin (Fragment) OS=Simulium vittatum OX=7192 PE=2 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 3.257e-10
Identity = 55/203 (27.09%), Postives = 87/203 (42.86%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFS----------AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYS--CQRLEKGQVTIFIGYGSDEN--ENDGILKYGTAVIGNFDEAFM------------------YLSRKRFGSGDGDSGAPIVIK 564
            R++ GE ++ +  P+            ++ HC GSIIS   ++TAAHC   +TN+   V  GS     K   G+ Y +  I  HPLY +      YDVA+L     +  N    A+  +   + +E   + I  G+G  +N  E   +L+  +A +  FD+                     YL+  R  S  GDSG P+ + 
Sbjct:   30 RIVGGEMTDISLIPYQVSVQTAISSYGFIHHCGGSIISPRWVVTAAHCA-QKTNSAYQVYTGSS---NKVEGGQAYRVKTIINHPLYDE--ETTDYDVALLELAEPIVMNYKTAAIELAEVGEEVETDAMAIVSGWGDTKNFGEEPNMLR--SAEVPIFDQELCAYLNANHGVVTERMICAGYLAGGR-DSCQGDSGGPLAVD 223          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P35587|HYPA_HYPLI (Hypodermin-A OS=Hypoderma lineatum OX=7389 PE=1 SV=2)

HSP 1 Score: 60.8474 bits (146), Expect = 8.939e-10
Identity = 45/142 (31.69%), Postives = 68/142 (47.89%), Query Frame = 1
Query:   16 IVFFLALTEASKRVLNGEFSETNQFPFSAYLG-----HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYG 426
            +V    L+++  R++ G  S+   FP+   L      +C GSI S + I+TAAHC+ +     L V VGS      E  G    I K +IH  Y +    K YDVA+L     L FN +I+A+  + +   +    I  G+G
Sbjct:   18 VVPLGMLSQSDGRIVGGVESKIEDFPWQISLQRDGRHYCGGSIYSKNVIITAAHCLRNVVAEELRVRVGSSYW---EHGGSLRNISKFQIHESYVE--PTKEYDVALLKLDSDLSFNSTIKAIELTNEIPPEYADAIVSGWG 154          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P98064|MASP1_MOUSE (Mannan-binding lectin serine protease 1 OS=Mus musculus OX=10090 GN=Masp1 PE=1 SV=2)

HSP 1 Score: 59.6918 bits (143), Expect = 4.197e-9
Identity = 57/247 (23.08%), Postives = 105/247 (42.51%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH------CSGSIISAHAILTAAHCVCHET----NATLH-----------VLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSD--ENENDGILKYGTAVIGN--FDEAFMYLSRK----------RFGSGD---GDSGAPIVIK--KNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWL 657
            R+ NG  ++    P+ A L H      C GS++ ++ +LTAAHC+ H++      TLH           +++G       +   ++  + +  +HPLY    +    D+ ++    S   N  +  V    Q   +G + I  G+G    +   + +++    ++ +    EA+  L +K          + G  D   GDSG P+V K  + + +  VG++      GK D Y +   IY   DW+
Sbjct:  453 RIFNGRPAQKGTMPWIAMLSHLNGQPFCGGSLLGSNWVLTAAHCL-HQSLDPEEPTLHSSYLLSPSDFKIIMGKHWRRRSDEDEQHLHVKRTTLHPLYNPSTFEN--DLGLVELSESPRLNDFVMPVCLPEQPSTEGTMVIVSGWGKQFLQRFPENLMEIEIPIVNSDTCQEAYTPLKKKVTKDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWI 696          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P12546|CERC_SCHMA (Cercarial protease OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 58.5362 bits (140), Expect = 6.386e-9
Identity = 54/218 (24.77%), Postives = 89/218 (40.83%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVL-NGE-FSETNQFPFSAYLG----HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKK-----------CGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQR--LEKGQVTIFIGYGSDENEND------GILKYGTAVIGNFDEA-----FMYLSRKRFG--SGDGDSGAPIV 558
            +++ L  + L     S  ++ +GE      +FPF A+L      C+GS++S  A+LTA HCVC          +  + G   +  G +++   +K+ P Y                L  +D+AI+     +     I+ ++          G     +GYG D+N+ D      GILK G A I     A         + + FG     GDSG P++
Sbjct:    9 VVVTLFTYCLTFERVSTWLIRSGEPVQHPAEFPFIAFLTTERTMCTGSLVSTRAVLTAGHCVCSPLPVIRVSFLTLRNG---DQQGIHHQPSGVKVAPGYMPSCMSARQRRPIAQTLSGFDIAIVMLAQMVNLQSGIRVISLPQPSDIPPPGTGVFIVGYGRDDNDRDPSRKNGGILKKGRATIMECRHATNGNPICVKAGQNFGQLPAPGDSGGPLL 223          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P35039|TRY5_ANOGA (Trypsin-5 OS=Anopheles gambiae OX=7165 GN=TRYP5 PE=2 SV=2)

HSP 1 Score: 58.5362 bits (140), Expect = 6.842e-9
Identity = 49/168 (29.17%), Postives = 77/168 (45.83%), Query Frame = 1
Query:   43 ASKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMS-GKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQR--LEKGQVTIFIGYG---SDENENDGILKYGTAVIGNFDEAFMYLSR 513
            A KR++ G     +  P+   L +     C GSI+S+  ILTAAHC+     +   V VGS     K  S G    + +I  HP++   G    YD+A+L  K  L F++ +Q +    Q   +E+G + I  G+G   S+ + ND +       +   +    Y SR
Sbjct:   44 AGKRIVGGFVINISDAPYQISLQYDDDHNCGGSILSSKWILTAAHCINDNAPSKPTVRVGSS----KHASGGTVIRVARIVPHPMH---GSKNNYDIALLELKNELTFSEKVQPIALPEQDEPIEEGTMGIVSGWGLTLSEADSNDVLRATNVPTVNQQECNKAYQSR 204          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A267EGM0 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024526g1 PE=3 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 2.260e-28
Identity = 71/208 (34.13%), Postives = 101/208 (48.56%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKR----VLNGEFSETNQFPFSAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIK--IHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD--GDSGAPIVIKKNNTFIQVGLIGG 603
            +L L++   AL  AS      VL G  +   QFPF+A+LG CS SI+ +  +LTA HCVC     +  VL G+  G   E   + Y +D  +  IHP Y  CG +   D+AIL T  ++ F   I A+         GQ     GYG DEN   G+LKY T+ + +       + +    +    GDSG P+ I  +    QVG++ G
Sbjct:    1 MLKLLIVACALGLASAMPDPYVLYGRTASQGQFPFAAWLGSCSASILDSRTVLTAGHCVCRSKPTS--VLFGAVQGNNPESGSRRYSLDTSRQVIHPRYTSCGTIGKDDIAILKTTTAISFTSVIGAITLHTSATSVGQSITIAGYGQDENRRSGVLKYATSTVESCRRFIGAVCQSMSPNSPYYGDSGGPLFITVSGQPRQVGVVSG 206          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A267EEB2 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024526g2 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 5.524e-28
Identity = 70/208 (33.65%), Postives = 101/208 (48.56%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKR----VLNGEFSETNQFPFSAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIK--IHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD--GDSGAPIVIKKNNTFIQVGLIGG 603
            +L L++   AL  AS      VL G  +   QFPF+A+LG CS SI+ +  +LTA HCVC     +  VL G+  G   E   + Y +D  +  IHP Y  CG +   D+AIL T  ++ FN  I A+         GQ     GYG DEN   G+LKY +  +         + +    +    GDSG P+ +  ++   QVG++ G
Sbjct:    1 MLKLLIVACALGLASAMPDPYVLYGRTASQGQFPFAAWLGSCSASILDSRTVLTAGHCVCRSKPTS--VLFGAVQGNNPESGSRRYSLDTSRQVIHPRYTSCGTIGKDDIAILKTTTAISFNSVIGAITLHTSATSVGQSITIAGYGQDENRRSGVLKYASNTVAACRRFTGAVCQSMSPNSPYYGDSGGPLFVTVSSQPRQVGVVSG 206          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A1I8J6X0 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001687g5 PE=3 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 1.727e-26
Identity = 69/208 (33.17%), Postives = 99/208 (47.60%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKR----VLNGEFSETNQFPFSAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIK--IHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD--GDSGAPIVIKKNNTFIQVGLIGG 603
            +L L++   AL  AS      VL G  +   QFPF+A+LG CS SI+ +  +LTA HCVC     +  VL G+  G   E   + Y +   +  IHP Y +CG +   D+AIL T  ++ F   I+ +         GQ     GYG DEN   G+LKY T  +         + +    +    GDSG P+ I  +    QVG++ G
Sbjct:    1 MLKLLIVACALGLASAMPDPYVLYGRTASQGQFPFAAWLGSCSASILDSRTVLTAGHCVCRSKPTS--VLFGAVQGNNPESGSRRYSLSTSRQVIHPGYTRCGTIGKDDIAILKTTSAISFTSVIKPITLHTSATSVGQSITIAGYGQDENRRSGVLKYATNTVAACRRFTGAVCQSMSPNSPYYGDSGGPLFISVSGQPRQVGVVSG 206          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A267EG23 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032521g2 PE=3 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 5.206e-26
Identity = 76/231 (32.90%), Postives = 111/231 (48.05%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKR----VLNGEFSETNQFPFSAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIK--IHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD--GDSGAPIVIKKNNTFIQVGLIGGK--SDNYTIGVPIYSFCDWLLNN 666
            +L LI+   AL  AS      VL G+ +E  QFPF+ +LG CS SI+ +  +LTA HCVC     +  VL G+  G   E   K Y +D  +  I+P Y +C  +   D+AI+ T   +EF   I+ +         GQ     GYG DEN   G+LKY T+ + +       + +    +    GDSG P+ I  +    QVG++ G   S+N  I   +Y    +L  N
Sbjct:    1 MLKLIIVACALGVASAMPDPYVLYGQTAEQGQFPFAGWLGFCSASILDSRTVLTAGHCVCRTRPTS--VLFGAVQGNRPESGSKRYSLDTSRQVINPKYTQCNTVGKDDIAIVKTTADIEFTDLIKPIVLHEAATSVGQSVTIAGYGQDENRRSGVLKYATSTVESCRRFIGAVCQSMSPNSPYYGDSGGPLFITVSGQPRQVGVVSGGDFSNNQAIYGNVYDNLSFLKAN 229          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A267EEB7 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032521g1 PE=3 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.352e-25
Identity = 72/208 (34.62%), Postives = 103/208 (49.52%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKR----VLNGEFSETNQFPFSAYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIK--IHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD--GDSGAPIVIKKNNTFIQVGLIGG 603
            +L LI+   AL  AS      VL G+ +E  QFPF+ +LG CS SI+    +LTA HCVC  T  T  VL G+  G   E   K Y +D  +  I+P Y +C  +   D+AI+ T + +EF   I+ +         GQ     GYG DEN   G+LKY T+ + +       + +    +    GDSG P+ I  +    QVG++ G
Sbjct:    1 MLKLIIVACALGVASALPDPYVLYGQTAEQGQFPFAGWLGFCSASILDRRTVLTAGHCVCR-TRPT-SVLFGAVQGNRPESGSKRYSLDTSRQVINPKYTQCNTVGKDDIAIVKTTVDIEFTDLIKPIVLYEAATSVGQSVTIAGYGQDENRRSGVLKYATSTVESCRRFIGAVCQSMSPNSPYYGDSGGPLFITVSGQPRQVGVVSG 206          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: f7l (coagulation factor VII-like [Source:NCBI gene;Acc:103046085])

HSP 1 Score: 64.3142 bits (155), Expect = 1.403e-11
Identity = 59/247 (23.89%), Postives = 96/247 (38.87%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLY--------------KKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC-----------------QRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGDGDSGAPIVIKKNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWLLNNV 669
            +V+ G      Q P+ A L +     C   ++++  ILTAAHCV  +  + + V VG  I + KE + +   + K+ IHPLY              ++   L PY V I     +  F +++  V  S                  QRLE  +V +          + G+      +   F E      +       GDSG P+V   N T+   G++       +SD Y I   +  F DW++  +
Sbjct:  195 KVVKGNLCPKGQCPWQALLEYKGVYKCGAIVLNSWWILTAAHCVWKQDISQIQVTVGEHIRFKKEGTEQTRRVSKVFIHPLYNHSSTDSDIALLRLRRNITLNPYIVPICLPPSNGTFVRTLGTVRMSTVSGWGLLSQFGPSSTVLQRLEVPKVPL-----EQCQAHSGLTLTNNMLCAGFKEGGRDACK-------GDSGGPLVTLYNKTWFLTGIVSWGKGCARSDMYGIYTRVSIFVDWIMKTM 429          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: tmprss3a (transmembrane serine protease 3 [Source:NCBI gene;Acc:103026237])

HSP 1 Score: 59.6918 bits (143), Expect = 4.799e-10
Identity = 55/208 (26.44%), Postives = 92/208 (44.23%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSG-KYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAV---NYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIG-------NFDEAFM-YLSRKRFGSG---------DGDSGAPIVIKKNNTFIQVG 591
            S R++ G  S   QFP+   L       C GSI++   ILTAAHCV       +  ++      P  +SG KY  ++KI  H  Y+  G    YD+A+L     L FN  ++ +   N+  +  E G++    G+G+ E+  +  +   +A +        +  E +  Y+S     +G          GDSG P+  + ++ +  VG
Sbjct:  313 STRIVGGNLSLEGQFPWQVSLQFQNEHLCGGSIVATRWILTAAHCVYGFAFPQVWTVLVGLTEQPVSVSGAKYLSVEKIIYHARYRPKGL--DYDIALLKLVEPLAFNGLVEPICLPNFG-EEFEDGKMCWISGWGATEDGGEASVSLHSARVPLISAKACSQPEVYQGYISPGMICAGYLEGGTDSCQGDSGGPLACEDSSVWKLVG 517          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: si:dkeyp-93a5.2 (si:dkeyp-93a5.2 [Source:ZFIN;Acc:ZDB-GENE-131127-18])

HSP 1 Score: 55.4546 bits (132), Expect = 9.067e-9
Identity = 51/225 (22.67%), Postives = 91/225 (40.44%), Query Frame = 1
Query:    1 MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC--QRLEKGQVTIFIGYGSDEN----ENDGILKYGTAVIGNFDEAFMYLSRKRF-------------GSGD---GDSGAPIVIKKNNTFIQVGL 594
            ++L+L V      + + R++ G+ +    +P+   L       C GS+I+   +LTAAHC  +     + VL+G +       +     + K+ +H  Y      +  D+ +L    S+ FNK I  V  +           +   G+G   +     + G+L+     I +  +    LS  +              G  D   GDSG P+V KK+  +IQ G+
Sbjct:    9 LVLFLCVRVCGRPQLNTRIVGGQAASPGSWPWQVSLQSFGFHFCGGSLINKDWVLTAAHCFQNTNEKDVKVLLGKQTLTGSNPNQIQRGVRKVIVHERYDP--NTQDNDITLLQLDSSVTFNKFIMPVCLAAAGSSFPAATASWITGWGDIASGVSLPDPGLLQEAQVPIVDQKQCASLLSLFKMKITNNMICAGLKQGGKDTCQGDSGGPMVNKKSTIWIQSGI 231          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000052381.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000521.1:7330:13647:-1 gene:ENSAMXG00000043941.1 transcript:ENSAMXT00000052381.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 9.189e-9
Identity = 42/136 (30.88%), Postives = 64/136 (47.06%), Query Frame = 1
Query:   46 SKRVLNGEFSETNQFPFSAYLGH-----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSG-KYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAV---NYSCQRLEKGQVTIFIGYG 426
            S R++ G  S   QFP+   L       C GSI++   ILTAAHCV       +  ++      P  +SG KY  ++KI  H  Y+  G    YD+A+L     L FN  ++ +   N+  +  E G++    G+G
Sbjct:  127 STRIVGGNLSLEGQFPWQVSLQFQNEHLCGGSIVATRWILTAAHCVYGFAFPQVWTVLVGLTEQPVSVSGAKYLSVEKIIYHARYRPKGL--DYDIALLKLVEPLAFNGLVEPICLPNFG-EEFEDGKMCWISGWG 259          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: cela1.6 (elastase-1-like [Source:NCBI gene;Acc:103040289])

HSP 1 Score: 54.299 bits (129), Expect = 2.609e-8
Identity = 33/115 (28.70%), Postives = 51/115 (44.35%), Query Frame = 1
Query:  100 AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNY--SCQRLEKGQVTIFIGYGSDEN 438
            +Y   C GS+I    ++TAAHCV  +T+ T  V++G    Y  E + +Y  +  + IHP +        YD+A+L        N  +Q  N   S Q L         G+G  + 
Sbjct:  103 SYYHTCGGSLIRRRWVMTAAHCV--DTSRTWRVVLGDHDIYTHEGTEQYMSVSNVYIHPSWNSNNVAGGYDIALLRLSADASLNSYVQLANLPPSGQVLPNNNPCYITGWGRTQT 215          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001315.1 (pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-1 gene:ENSPMAG00000001180.1 transcript:ENSPMAT00000001315.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 5.187e-8
Identity = 51/213 (23.94%), Postives = 86/213 (40.38%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLG-------HCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGK------YYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNY--SCQRLEKGQVTIFIGYGS----------DENENDGILKYGTAVIGNFDEAFMYLSRKRFGSG------DGDSGAPIVIKKNNTFIQVGLI 597
            R++ GE +    +P+ A L        HC GS+I    +LTAAHCV +  N  +  L    + + K +  K      +  I +I +H  Y        YD+A+L     +   + +Q V    +      GQ+    G+G+          +  E    L   +  IG++D A   +    +  G       GDSG P+V +   ++   GL+
Sbjct:   88 RIVGGESALAGAWPWQASLWSGLTKNHHCGGSLIHPKWVLTAAHCV-YGKNCRVEALSDWTLFFGKLLLDKEGPMEQHRSIRQIVVHRQYVS--SENDYDIALLELDSPVNLTEQVQTVCMPAASHAFLPGQMCWVSGWGTVIGNEFSLSNNMQEVQLPLISQSDCIGSYDHATPRMLCAGYPDGGKDACQQGDSGGPLVCEDRGSWFLAGLV 297          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003778.1 (pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 gene:ENSPMAG00000003419.1 transcript:ENSPMAT00000003778.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 2.113e-6
Identity = 58/253 (22.92%), Postives = 104/253 (41.11%), Query Frame = 1
Query:   49 KRVLNGEFSETNQFPFSAYLGH-------CSGSIISAHAILTAAHCVCHE------TNATLHVLVG--SKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLE--------KGQVT----IFIGYGSDENENDGILKYGTAVIGNFDEAFMYLSR----------------KRFGSGDGDSGAPIVIK--KNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWL 657
            +RV++G+ +E    P+   L         C  S+IS   +LTAAHCV +       T   L V +G  +K GY K+   K   +DKI IH  Y     ++  D+A+L+    + F + I  +    + +         KG+VT    +F  + ++      +L+     I + +      +                 KR  + +GDSG P ++K  ++  + Q+G++       +   Y I   +Y    W+
Sbjct:  358 QRVVHGDNAEEGSAPWQVMLYRKSPMDMLCGASLISDQWVLTAAHCVFYPPWDKNFTAKELAVRIGKHNKAGYEKDRE-KISNVDKIIIHSKYNWKENME-RDIALLHLDKPITFTQYIVPICLPTRDVAVSLLKSGFKGRVTGWGNLFQTWTNNPRAQPKVLQMINLPIVDPNRCQASTTHRITANMLCAGYEPEDVKRGDACEGDSGGPFIMKDFESKRWYQMGIVSWGEGCDRDGKYGIYTHVYRLRKWI 608          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO44208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW61])

HSP 1 Score: 59.3066 bits (142), Expect = 9.197e-11
Identity = 53/233 (22.75%), Postives = 102/233 (43.78%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLG------HCSGSIISAHAILTAAHCVCHETNATLH-VLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKS--IQAVNYSCQRLEKGQVTIFIGYGS---DENENDGILKYGTAVIGNFDE-----------AFMYLSRKR---FGSGDGDSGAPIVIKKNNTF-----IQVGLIGGKSDNYTIGVPIYSFCDWL 657
            R++NG+ ++ + +P+   L        C GS+IS   ++TAAHC+    N   + V+VG+          +   + +I  HP Y     +   D+A++     ++F+ +  +  V  + QR   G+     G+G+   D  ++  IL+     I + +            A +     R    G  +GDSG P+V + N ++     +  GL    + +YT+   + S+ DW+
Sbjct:    2 RIINGQNAQPHSWPWQISLRGRSGFHTCGGSLISDRWVVTAAHCIHRNKNPGGYTVVVGAHKKRGSTSVQQSLRLSQIIEHPKYNDRRIVN--DIALIELATPVQFDSAGKVGTVCLTDQRPAPGKRCYITGWGAINGDTQQSPDILQQAMLPIASHENCRRKYGDVSSTAHLCAGEARSDAAGGCNGDSGGPLVCEDNGSWFLHGAVSYGLRNCPTTHYTVFARVASYTDWI 232          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO44207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW60])

HSP 1 Score: 56.225 bits (134), Expect = 1.042e-9
Identity = 53/238 (22.27%), Postives = 105/238 (44.12%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH------CSGSIISAHAILTAAHCVCHETN-ATLHVLVGSKIGYPKEMSG-----KYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKS--IQAVNYSCQRLEKGQVTIFIGYGS---DENENDGILKYGTAVIGNFDE-----------AFMYLSRKR---FGSGDGDSGAPIVIKKNNTF-----IQVGLIGGKSDNYTIGVPIYSFCDWL 657
            R++NG+ ++ + +P+   L        C G++IS   ++TA+HC+  + N  +  V+VG+       MSG     K   + ++  HP Y     +   D+A++     +EF+ +  +  V  + QR   G+     G+G+      ++  IL+     I + +            A +     R    G  +GDSG P+V + N ++     +  G+    + +YT+   + S+ DW+
Sbjct:    2 RIINGQNAQPHSWPWQISLRQGRRFHLCGGALISDRWVVTASHCIHDDLNPGSYMVVVGA-----HRMSGSTSVEKTIRVSQVLEHPRYDSQRDVN--DIALIELATPVEFDSAGKVGTVCLTNQRPAPGKQCYITGWGAVNGHTQQSPDILQQAMLPIASHENCRRKYGDVSSTAHLCAGEARSDAAGGCNGDSGGPLVCEDNGSWFLHGAVSYGMKYCPTTHYTVFARVASYTDWI 232          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO31858 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWQ5])

HSP 1 Score: 55.8398 bits (133), Expect = 1.731e-9
Identity = 49/212 (23.11%), Postives = 94/212 (44.34%), Query Frame = 1
Query:   40 EASKRVLNGEFSETNQFPFSAYLGH------CSGSIISAHAILTAAHCVCHETNATLHVLVGS-KIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC-----QRLEKGQVTIFIGYG--SDENENDGILKYGTAVI----------GNFDEAFMYLSRKRFG--SGDGDSGAPIVIKKNNTFIQVGLI 597
            + S R++ G  +  N +P+ A L        C G+++    ++TA+HC+  +T ++L + +G+ +     E + + + + +I  H  Y K   L   D+A++  +     N+   AVN +C       +++G+     G+G  S+   +  +L      I          G   E+ +   R   G  S  GDSG P+V + N  F   G++
Sbjct:    2 KPSTRIVGGTAAPKNAWPWQAQLRSASGFPFCGGTLVHPRFVVTASHCIVKKTPSSLRIRLGAHRRADSGESTVQDFRVKRIIKHERYSKPVNLA-NDIAVIELEQPARLNR---AVNLACLPTQSNEIQEGKRCWVTGWGRTSEGGSSPTVLMQVEVPIVSASTCSRAYGRLHESMVCAGRASGGIDSCQGDSGGPMVCEYNGKFNLEGVV 209          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO39910 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8P7])

HSP 1 Score: 54.299 bits (129), Expect = 5.855e-9
Identity = 51/240 (21.25%), Postives = 94/240 (39.17%), Query Frame = 1
Query:   55 VLNGEFSETNQFPFSAYLG-----HCSGSIISAHAILTAAHCVCHETNAT----LHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC-----QRLEKGQVTIFIGY----GSDENENDGILKYGTAVIGNFDE------------AFM---YLSRKRFGSGDGDSGAPIVIKKN------NTFIQVGLIGGKSDNYTIGVPIYSFCDWL 657
            +++G  ++ N +P+   +      HC G+++S   ++TAAHCV H  +      L + +G       E + + + + +I +HP Y +   +   D+A++        NK    VN +C     + L  G++    G+    G D      +LK     + N  E            A M   Y  R    + + DSG P+V K           +  G       +Y++   +  F  W+
Sbjct:    1 MISGSDAQPNSWPWMVQINYNNGHHCGGTLVSPQWVVTAAHCVDHVKDPKNYNELAITLGEHKRSASEGTEQRFSVARIIVHPQYFEPTAIN-NDIALIKLNKPARLNK---YVNLACLPRQGEELSDGKICYATGWGLTVGGDWKSQSDVLKQTPLPVVNRQECQTDYDDIPITTAMMCTGYGGRSSISTCNTDSGGPVVCKSKLGHWYLQGVVSFGARACAPGHYSVNAKVSKFVTWI 236          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO43454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYF8])

HSP 1 Score: 53.9138 bits (128), Expect = 6.866e-9
Identity = 58/239 (24.27%), Postives = 101/239 (42.26%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFSAYLGH------CSGSIISAHAILTAAHCVCHE----TNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFD-----EAFMYL----SRKRF--------GSGDGDSGAPIVIKKNNTFIQVGLIG----GKSDNYTIGV--PIYSFCDWLLNNV 669
            +++ G+ +E   +P+   +G+      C GSI+++  I+TAAHCV  +    +  T++     ++ Y  + S +   I+ I +HP Y        YD+A+L  +  + FN  +  V      L  G      G+G     + G      A I   D     E +  L    +R R         G+  GDSG P+V +    ++ +G+      G +D+   GV   +  F DW+   V
Sbjct:    1 QIVGGKVTEHGAWPWQVQIGYKTMGHICGGSIVNSQWIVTAAHCVTTKPPGASRYTMYAFSEHQL-YQLDGSEQNIPIEGIVVHPSYNDLD----YDIALLKLRQPITFNAYVSQVCLPQAALLAGTPCYVSGWGRIGESSPGSNVLQEASIPLVDQRACEEQYRNLKPITARMRCAGIYGTPKGTCKGDSGGPLVCESKGRWVLMGVTSWSYNGCADSGYAGVYADVVYFKDWIRQTV 234          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008752.2 (elastase-1 [Source:NCBI gene;Acc:101156319])

HSP 1 Score: 58.9214 bits (141), Expect = 4.302e-10
Identity = 32/113 (28.32%), Postives = 52/113 (46.02%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFS---------AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ 363
            RV+ GE +  N +P+          +Y   C GS+I    ++TAAHCV  + + T  V+VG    Y  E   +Y  + ++ +HP +        YD+A+L        N  +Q
Sbjct:   33 RVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGSLIKTGWVMTAAHCV--DRSMTWRVVVGDHDIYTNEGREQYLSVSQVYVHPSWNTNNVAAGYDIALLRLSTPATLNSYVQ 143          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000035554.1 (elastase-1 [Source:NCBI gene;Acc:101156319])

HSP 1 Score: 58.9214 bits (141), Expect = 4.941e-10
Identity = 32/113 (28.32%), Postives = 52/113 (46.02%), Query Frame = 1
Query:   52 RVLNGEFSETNQFPFS---------AYLGHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQ 363
            RV+ GE +  N +P+          +Y   C GS+I    ++TAAHCV  + + T  V+VG    Y  E   +Y  + ++ +HP +        YD+A+L        N  +Q
Sbjct:   33 RVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGSLIKTGWVMTAAHCV--DRSMTWRVVVGDHDIYTNEGREQYLSVSQVYVHPSWNTNNVAAGYDIALLRLSTPATLNSYVQ 143          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040448.1 (pep primary_assembly:ASM223467v1:8:2449519:2451077:1 gene:ENSORLG00000025659.1 transcript:ENSORLT00000040448.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 5.140e-10
Identity = 51/208 (24.52%), Postives = 89/208 (42.79%), Query Frame = 1
Query:   31 ALTEASKRVLNGEFSETNQFPFSAYLGH----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAV--NYSCQRLEKGQVTIFIGYGSDENENDGILKYGTAVIGNFDEAFMY----LSRKRFGSG---------DGDSGAPIVIKKNNTFIQVGLI 597
             L   + R++ G+ +    +P+   L      C GS+I+   +LTAAHC    + + ++ ++G +       +     I  + +HP Y      +  D+A+L     + FN  I  V    +      G  T   G+G  +  N G L+    ++GN      Y    ++     +G          GDSG P+VIK+NN +IQ G++
Sbjct:   19 GLANLNSRIVGGQNALPGSWPWQVSLQSSYHFCGGSLINNQWVLTAAHCFPSRSASGVNAVLGLQSLQGSNPNRVSRTIKTVIVHPNYNS--GTQNNDIALLQLSSPVTFNNYITPVCLPSTGSTFYSGVKTWVTGWG--DIGNGGQLEIQIPIVGNRRCKCSYGASSITDNMMCAGLLAGGKDSCQGDSGGPLVIKQNNRWIQAGVV 222          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034265.1 (tryptase [Source:NCBI gene;Acc:101156896])

HSP 1 Score: 57.7658 bits (138), Expect = 1.357e-9
Identity = 52/212 (24.53%), Postives = 91/212 (42.92%), Query Frame = 1
Query:   31 ALTEASKRVLNGEFSETNQFPFSAYL--------GHCSGSIISAHAILTAAHCVCHETNATLHV-LVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSC--QRLEKGQVTIFIGYGSDENENDGILK-YGTAVIGNFDEAFMY-----------LSRKRFGSGDGDSGAPIVIKKNNTFIQVGLI 597
            A+TE+  R++ G+ +   Q+P+ A L          C GS+I++  IL+AAHC    +N  + +  +  +   P ++S     + KI +HP Y         D+ +L     + FN  I  V  +        G  +   G+G+  +   G L+     ++ N      Y           L+     S  GDSG P+VIK +  ++Q G++
Sbjct:   32 AVTES--RIVGGQDAAAGQWPWQAMLQIPVAGGTALCGGSLINSQWILSAAHCFKSTSNVVVSLGRITEQGSNPHQVS---LSVSKIIVHPNYDS--RTNNNDLTLLKLASPVTFNDYISPVCLAAAGSDFPGGTSSWVTGFGTLSSGGQGSLQEVNIPIVSNTQCNSAYGGITNQMICAGLTTGGLDSCQGDSGGPLVIKNSTRWVQAGVV 236          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000000344.2 (pep primary_assembly:ASM223467v1:8:908677:912329:-1 gene:ENSORLG00000000282.2 transcript:ENSORLT00000000344.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 2.754e-9
Identity = 46/201 (22.89%), Postives = 83/201 (41.29%), Query Frame = 1
Query:   31 ALTEASKRVLNGEFSETNQFPFSAYLGH----CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQR--LEKGQVTIFIGYGSD----ENENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGL 594
             L +   R++ GE +    +P+ A + +    C GS+IS   +LTAA C+    ++ + V +G        +      + K+  HP Y    +    D+A+L     + F   I+ V  + +R     G      G+G+     E +   + +    ++ N      Y + K     D   GD G P+V+   N +IQ G+
Sbjct:   21 PLRKPHTRIIGGEDAPAGVWPWQASVHNNSTLCGGSLISRRWVLTAARCLSRSADSHVVVFLGRDTQMGPNLHEVMRWVSKVIKHPDYDPGTHKN--DLALLRLSSPVNFTDYIRPVCLAAKRSFFVDGLSCWVTGWGAPQTNGEEKRPRLQQVSVPIVSNIQCNAAYGTGKVTNQDDVCRGDFGGPLVVSYGNRWIQAGV 219          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000045112.1 (SMESG000045112.1)

HSP 1 Score: 50.8322 bits (120), Expect = 1.694e-7
Identity = 53/181 (29.28%), Postives = 71/181 (39.23%), Query Frame = 1
Query:  109 GHCSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKI------HPLYKKCGYLKP-----YDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDE-NENDGILKYGTAVIGNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIGGK 606
            G CSGSII+   I+TAAHC+    N            Y +  + +   I K KI          K C   KP      D++I      + FNK IQ  + S           F+GYGSD    N   L+   A I + D   +Y S       D   GDSG P++ K     I +  +  K
Sbjct:   57 GFCSGSIINQWKIVTAAHCIHKRHNI-----------YIQPYNHRMLNISKNKIVRCHFMKEFIKNCLIEKPNNICYNDLSICTVDKKIIFNKYIQPASISTTFHGNNLSVYFLGYGSDLFGTNTYRLRQKYATINSCDSNKLYCSYSVHSKPDVSPGDSGGPVIYKNKQIGITIAYLEKK 226          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000004375.1 (SMESG000004375.1)

HSP 1 Score: 50.0618 bits (118), Expect = 7.146e-7
Identity = 56/208 (26.92%), Postives = 89/208 (42.79%), Query Frame = 1
Query:  106 LGHCSGSIISAHAILTAAHCVCHETNATLH-VLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYLKPYDVAILYTKLSLEFNKSIQAVNYSCQRLEK----GQVTIFIGYGSDENE-NDGILKYGTAVI----------GNFDEAFMYLSRKRFGSGD---GDSGAPIVIKKNNTFIQVGLIG-----GKSDNYTIGVPIYSFCDWL 657
            L  C GS+I+   +LTAAHC   ++N   + + +G    Y   +      ++KI +HP YK     + +D+AI+  K   +   SIQ V   C   +K    G+  + +G+GS +    +G+LK     I          GN     M  +  + G  D   GDSG P+V K    F   G++         +   +   I  F DW+
Sbjct:  295 LHMCGGSLIAEDFVLTAAHCFIMDSNPDYYNIDLGRYFLYKGLVEN--IAVEKIFLHPSYK--IETQDFDLAIVKLKRKAKLTASIQTV---CIPRDKEPIAGKKCVILGWGSTQGTGGEGVLKQAVVPIVERNVCNELYGNIITNQMLCAGYKTGGIDSCSGDSGGPLVCKTEKKFEIYGIVSFGQGCALPNRPGVYTNIVRFVDWI 495          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042396.1 (SMESG000042396.1)

HSP 1 Score: 47.3654 bits (111), Expect = 1.985e-6
Identity = 42/160 (26.25%), Postives = 76/160 (47.50%), Query Frame = 1
Query:    4 ILYLIVFFLALTEASKRVLNGEFSETNQFPFSA---YLGH--CSGSIISAHAILTAAHCVCHETNATLHVLVGSKIGYP------KEMSG--KYYEIDKIKIHPLYK-KCGYLKPYDVAILYTKLSLEFNKSIQAVNYS----CQRLEKGQVTIFIGYGS 429
            IL + + F++   A  +V+NG  S  +++P       LG   C G++++ + +LTAAHC+   T+  L  L   K+         + +SG  K +++ K  +HP Y  +  YL   DV ++     ++ N   Q + Y+        E G+    +G+GS
Sbjct:    6 ILIVFLIFISTVSAEWKVINGTQSILHEYPQMVSIRLLGEHICGGTLLNENTVLTAAHCIWPMTDWKLETLKEYKVEIVLGEYDLERVSGEEKIFQVTKNLVHPDYTYEMSYLNGNDVGLIKFDGKVQ-NNEFQYIKYTEYQNISTYEIGERCEVVGWGS 164          
The following BLAST results are available for this feature:
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CELA16.158e-826.89chymotrypsin like elastase 1 [Source:HGNC Symbol;A... [more]
TMPRSS11D8.618e-828.17transmembrane serine protease 11D [Source:HGNC Sym... [more]
TMPRSS32.338e-726.86transmembrane serine protease 3 [Source:HGNC Symbo... [more]
TMPRSS32.791e-726.86transmembrane serine protease 3 [Source:HGNC Symbo... [more]
TMPRSS32.791e-726.86transmembrane serine protease 3 [Source:HGNC Symbo... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
try-11.127e-825.00TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
svh-15.542e-725.36HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
l(2)k059112.629e-1227.20gene:FBgn0284244 transcript:FBtr0305556[more]
CG75424.107e-1126.80gene:FBgn0036738 transcript:FBtr0345386[more]
CG75424.107e-1126.80gene:FBgn0036738 transcript:FBtr0075181[more]
CG300875.410e-1125.73gene:FBgn0050087 transcript:FBtr0100573[more]
CG312655.543e-1025.21gene:FBgn0051265 transcript:FBtr0083402[more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
f7l6.642e-1222.27coagulation factor VII, like [Source:ZFIN;Acc:ZDB-... [more]
cela1.62.574e-1128.06chymotrypsin like elastase family member 1, tandem... [more]
cela1.62.684e-1128.06chymotrypsin like elastase family member 1, tandem... [more]
prss60.13.180e-1025.41serine protease 60.1 [Source:ZFIN;Acc:ZDB-GENE-070... [more]
cela1.34.046e-1027.03chymotrypsin like elastase family member 1, tandem... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tenm22.755e-1427.49teneurin transmembrane protein 2 [Source:Xenbase;A... [more]
tenm25.077e-1427.62teneurin transmembrane protein 2 [Source:Xenbase;A... [more]
tenm21.176e-1327.01teneurin transmembrane protein 2 [Source:Xenbase;A... [more]
ENSXETT00000027919.17.816e-1126.96pep primary_assembly:Xenopus_tropicalis_v9.1:2:653... [more]
ENSXETT00000046747.13.186e-1027.59chymotrypsin like elastase 1, gene 3 [Source:NCBI ... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Masp16.001e-1023.08mannan-binding lectin serine peptidase 1 [Source:M... [more]
Prss382.637e-925.58protease, serine 38 [Source:MGI Symbol;Acc:MGI:268... [more]
Klk63.417e-925.37kallikrein related-peptidase 6 [Source:MGI Symbol;... [more]
Klk63.417e-925.37kallikrein related-peptidase 6 [Source:MGI Symbol;... [more]
Klk63.417e-925.37kallikrein related-peptidase 6 [Source:MGI Symbol;... [more]
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BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P35048|TRYP_SIMVI3.257e-1027.09Trypsin (Fragment) OS=Simulium vittatum OX=7192 PE... [more]
sp|P35587|HYPA_HYPLI8.939e-1031.69Hypodermin-A OS=Hypoderma lineatum OX=7389 PE=1 SV... [more]
sp|P98064|MASP1_MOUSE4.197e-923.08Mannan-binding lectin serine protease 1 OS=Mus mus... [more]
sp|P12546|CERC_SCHMA6.386e-924.77Cercarial protease OS=Schistosoma mansoni OX=6183 ... [more]
sp|P35039|TRY5_ANOGA6.842e-929.17Trypsin-5 OS=Anopheles gambiae OX=7165 GN=TRYP5 PE... [more]
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BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EGM02.260e-2834.13Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A267EEB25.524e-2833.65Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A1I8J6X01.727e-2633.17Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A267EG235.206e-2632.90Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A267EEB71.352e-2534.62Peptidase S1 domain-containing protein OS=Macrosto... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
f7l1.403e-1123.89coagulation factor VII-like [Source:NCBI gene;Acc:... [more]
tmprss3a4.799e-1026.44transmembrane serine protease 3 [Source:NCBI gene;... [more]
si:dkeyp-93a5.29.067e-922.67si:dkeyp-93a5.2 [Source:ZFIN;Acc:ZDB-GENE-131127-1... [more]
ENSAMXT00000052381.19.189e-930.88pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
cela1.62.609e-828.70elastase-1-like [Source:NCBI gene;Acc:103040289][more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000001315.15.187e-823.94pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-... [more]
ENSPMAT00000003778.12.113e-622.92pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 g... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO442089.197e-1122.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO442071.042e-922.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318581.731e-923.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO399105.855e-921.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434546.866e-924.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000008752.24.302e-1028.32elastase-1 [Source:NCBI gene;Acc:101156319][more]
ENSORLT00000035554.14.941e-1028.32elastase-1 [Source:NCBI gene;Acc:101156319][more]
ENSORLT00000040448.15.140e-1024.52pep primary_assembly:ASM223467v1:8:2449519:2451077... [more]
ENSORLT00000034265.11.357e-924.53tryptase [Source:NCBI gene;Acc:101156896][more]
ENSORLT00000000344.22.754e-922.89pep primary_assembly:ASM223467v1:8:908677:912329:-... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000045112.11.694e-729.28SMESG000045112.1[more]
SMESG000004375.17.146e-726.92SMESG000004375.1[more]
SMESG000042396.11.985e-626.25SMESG000042396.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032570 ID=SMED30032570|Name=Peptidase S1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=714bp
ATGATTTTGTACTTAATAGTGTTCTTTTTAGCTTTGACTGAAGCTTCCAA
GCGTGTACTAAATGGAGAATTTTCTGAAACAAACCAGTTTCCGTTTTCTG
CATATTTGGGACATTGTTCAGGTTCAATAATTTCTGCCCATGCAATCCTG
ACGGCTGCACATTGTGTTTGTCATGAAACAAATGCTACTTTGCATGTGTT
GGTAGGATCAAAAATTGGATATCCAAAAGAGATGAGTGGAAAATATTATG
AAATTGACAAAATTAAAATTCATCCTCTTTACAAGAAATGTGGATATTTA
AAACCGTATGATGTTGCCATTCTCTACACCAAACTTTCTCTAGAATTCAA
CAAGTCAATTCAGGCTGTTAACTACAGTTGTCAAAGATTGGAAAAAGGTC
AAGTAACCATTTTTATTGGATATGGATCTGATGAAAATGAGAATGACGGA
ATTTTAAAGTATGGTACAGCAGTTATTGGTAATTTTGATGAAGCATTTAT
GTACCTCTCTCGGAAGAGATTTGGAAGTGGGGACGGTGATAGTGGAGCTC
CAATTGTAATAAAGAAAAATAATACATTTATTCAGGTTGGGCTTATTGGC
GGAAAAAGTGACAATTATACGATCGGAGTTCCTATATATTCGTTTTGTGA
TTGGTTGTTAAACAACGTATAACGTTTCAATTTTTTAAAAAAACATTTCA
GACTTCAAAAAAAA
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protein sequence of SMED30032570-orf-1

>SMED30032570-orf-1 ID=SMED30032570-orf-1|Name=SMED30032570-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=224bp
MILYLIVFFLALTEASKRVLNGEFSETNQFPFSAYLGHCSGSIISAHAIL
TAAHCVCHETNATLHVLVGSKIGYPKEMSGKYYEIDKIKIHPLYKKCGYL
KPYDVAILYTKLSLEFNKSIQAVNYSCQRLEKGQVTIFIGYGSDENENDG
ILKYGTAVIGNFDEAFMYLSRKRFGSGDGDSGAPIVIKKNNTFIQVGLIG
GKSDNYTIGVPIYSFCDWLLNNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
PLANA:0002075pigment cell
Vocabulary: INTERPRO
TermDefinition
IPR001254Trypsin_dom
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0008233peptidase activity
GO:0008236serine-type peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
GO:0005576extracellular region