Neuroligin-4, X-linked
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032503 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Match: NLGN1 (neuroligin 1 [Source:HGNC Symbol;Acc:HGNC:14291]) HSP 1 Score: 194.126 bits (492), Expect = 3.908e-51 Identity = 169/591 (28.60%), Postives = 260/591 (43.99%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT----SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S +++ M +G NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGERRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVG--CNVSDTVELVECLQKKPYKELVD-QDIQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 614
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Match: NLGN1 (neuroligin 1 [Source:HGNC Symbol;Acc:HGNC:14291]) HSP 1 Score: 194.126 bits (492), Expect = 3.908e-51 Identity = 169/591 (28.60%), Postives = 260/591 (43.99%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT----SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S +++ M +G NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGERRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVG--CNVSDTVELVECLQKKPYKELVD-QDIQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 614
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Match: NLGN4X (neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287]) HSP 1 Score: 190.274 bits (482), Expect = 7.650e-50 Identity = 172/635 (27.09%), Postives = 278/635 (43.78%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLK---FSSRIGPTISNQLF--TYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + + L F I + + ++G R L + +P + PV Y G+ YAS E RF PP +TG +FA VCPQ+L D + W ++ ++ +++ Q+E+CL LNIYVP ++ S PV+++IHG S+ G+GN D S LASYG +I IT+NYRLG+LGF+ + D A+GNY D AL+WI N+ F GD +VT+ G G + LF + II +G LS W+ +N R L + N+L ++ L+ + I TI+ + + + +++P + E D+++G+N G F ++ + + F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 LNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILG---PVEQYLGVPYAS------PPTGERRFQPPEPP---SSWTGIRNTTQFAAVCPQHL----DERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA---------------VNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Match: NLGN4X (neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287]) HSP 1 Score: 190.274 bits (482), Expect = 7.650e-50 Identity = 172/635 (27.09%), Postives = 278/635 (43.78%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLK---FSSRIGPTISNQLF--TYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + + L F I + + ++G R L + +P + PV Y G+ YAS E RF PP +TG +FA VCPQ+L D + W ++ ++ +++ Q+E+CL LNIYVP ++ S PV+++IHG S+ G+GN D S LASYG +I IT+NYRLG+LGF+ + D A+GNY D AL+WI N+ F GD +VT+ G G + LF + II +G LS W+ +N R L + N+L ++ L+ + I TI+ + + + +++P + E D+++G+N G F ++ + + F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 LNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILG---PVEQYLGVPYAS------PPTGERRFQPPEPP---SSWTGIRNTTQFAAVCPQHL----DERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA---------------VNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Match: NLGN4X (neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287]) HSP 1 Score: 190.274 bits (482), Expect = 7.650e-50 Identity = 172/635 (27.09%), Postives = 278/635 (43.78%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLK---FSSRIGPTISNQLF--TYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + + L F I + + ++G R L + +P + PV Y G+ YAS E RF PP +TG +FA VCPQ+L D + W ++ ++ +++ Q+E+CL LNIYVP ++ S PV+++IHG S+ G+GN D S LASYG +I IT+NYRLG+LGF+ + D A+GNY D AL+WI N+ F GD +VT+ G G + LF + II +G LS W+ +N R L + N+L ++ L+ + I TI+ + + + +++P + E D+++G+N G F ++ + + F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 LNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILG---PVEQYLGVPYAS------PPTGERRFQPPEPP---SSWTGIRNTTQFAAVCPQHL----DERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA---------------VNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Match: nlg-1 (Neuroligin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG1]) HSP 1 Score: 187.193 bits (474), Expect = 2.384e-49 Identity = 159/588 (27.04%), Postives = 271/588 (46.09%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 601
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Match: nlg-1 (Neuroligin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG1]) HSP 1 Score: 186.037 bits (471), Expect = 6.750e-49 Identity = 159/588 (27.04%), Postives = 271/588 (46.09%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 601
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Match: nlg-1 (Neuroligin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG1]) HSP 1 Score: 185.267 bits (469), Expect = 1.110e-48 Identity = 159/588 (27.04%), Postives = 271/588 (46.09%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 601
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Match: nlg-1 (Neuroligin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG1]) HSP 1 Score: 183.341 bits (464), Expect = 5.042e-48 Identity = 160/591 (27.07%), Postives = 272/591 (46.02%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTD---FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ F K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKRFRAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 604
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Match: nlg-1 (Neuroligin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG1]) HSP 1 Score: 183.341 bits (464), Expect = 5.068e-48 Identity = 160/591 (27.07%), Postives = 272/591 (46.02%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTD---FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ F K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKRFRAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 604
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Match: Nlg3 (gene:FBgn0083963 transcript:FBtr0333927) HSP 1 Score: 215.312 bits (547), Expect = 8.834e-58 Identity = 186/670 (27.76%), Postives = 290/670 (43.28%), Query Frame = 1
Query: 112 LSGIPINLSSNS-PPVRGYFGIRYAS--LGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNY-NSYWHHIKRILPFLEHQDEECLTLNIYVP-----------------------------------------ENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNL---AQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-------------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKL----LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLS----------------------------------------RNLVPSNKDFYREL---DVLVGLNGDNAGFFFNAPLLLKNNDFS---ELKFQSK-LKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP-----NH--RKYSHME--LSRTMMKYLSNFVKFG--XXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
+SG+ + L PV Y GI YAS +G + RF PPV++ + +G D+F+PVCPQ LP++ + + ++KR+LP+L++Q E+CL LNIYVP + + +PVL+F+HGES+E SGN YD S LASYGQI+ +T+NYRLG+LGF+ ++ + NY DI AAL W+ NI F GD N +TL GHG + LF+R I+++G+GL+ WS Y + ++N +S L L + L+ + + +L P+ F+ GP+I + + N+V K +L D++ G+ A F FN+ D E +S+ LK +++ Y ++ I+ + + YTDW++ + R+E+ + ++DA + PA Q ++HS+ S YLY+F Q + +DL +FG P NH R Y+ E LS +M Y SNFV+ G N + + +++ W Y K+Y+NFD K K R++ S W LIP LH+
Sbjct: 165 ISGVIVQLDGRHLDPVEAYRGIPYASPPVGNL--------RFMPPVSAAMW---SGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFA--FGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNS------GDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETL-----EALSDAQVVAPAAQTVDLHSADHRNS------YLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLS----FWLNLIPDLHK 800
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Match: Nlg3 (gene:FBgn0083963 transcript:FBtr0301072) HSP 1 Score: 215.312 bits (547), Expect = 8.834e-58 Identity = 186/670 (27.76%), Postives = 290/670 (43.28%), Query Frame = 1
Query: 112 LSGIPINLSSNS-PPVRGYFGIRYAS--LGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNY-NSYWHHIKRILPFLEHQDEECLTLNIYVP-----------------------------------------ENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNL---AQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-------------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKL----LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLS----------------------------------------RNLVPSNKDFYREL---DVLVGLNGDNAGFFFNAPLLLKNNDFS---ELKFQSK-LKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP-----NH--RKYSHME--LSRTMMKYLSNFVKFG--XXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
+SG+ + L PV Y GI YAS +G + RF PPV++ + +G D+F+PVCPQ LP++ + + ++KR+LP+L++Q E+CL LNIYVP + + +PVL+F+HGES+E SGN YD S LASYGQI+ +T+NYRLG+LGF+ ++ + NY DI AAL W+ NI F GD N +TL GHG + LF+R I+++G+GL+ WS Y + ++N +S L L + L+ + + +L P+ F+ GP+I + + N+V K +L D++ G+ A F FN+ D E +S+ LK +++ Y ++ I+ + + YTDW++ + R+E+ + ++DA + PA Q ++HS+ S YLY+F Q + +DL +FG P NH R Y+ E LS +M Y SNFV+ G N + + +++ W Y K+Y+NFD K K R++ S W LIP LH+
Sbjct: 165 ISGVIVQLDGRHLDPVEAYRGIPYASPPVGNL--------RFMPPVSAAMW---SGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFA--FGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNS------GDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETL-----EALSDAQVVAPAAQTVDLHSADHRNS------YLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLS----FWLNLIPDLHK 800
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Match: Nlg1 (gene:FBgn0051146 transcript:FBtr0305969) HSP 1 Score: 179.104 bits (453), Expect = 6.121e-46 Identity = 146/491 (29.74%), Postives = 230/491 (46.84%), Query Frame = 1
Query: 223 RFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWH-HIKRILPFLEHQDEECLTLNIYVP-ENNHTSP--FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMK-SDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS--------QFSHMYMNALGKYMNVS-SKLLFRQLKREPITNILKASEFTPKLKFSSRIGP-----TISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYV-YNQQSIYEI-----LYHLYTDWQKM--DPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP-------NHRKYSHME--LSRTMMKYLSNFVKFG 1554
RF PP A ++ G I PVCPQ LP+++ +N + H H+ R+LP+L + E+CL LN+YVP E ++P + VL+++HGESFE SGN YD S L+SYG++I +T+NYRLG+LGF++ S D NYA D AAL WI NI F GD+++VTLMGH + LFHR I+++G+ +S W+ S Q +H L +++ +L L+ +IL T +FS+ +GP I NQ + + + + D+L G+ + A L + L+E ++N + + QS ++I L +Q M +P+ E + + +++DA + P LQ H +D + Y+Y+F + + + ++L +FG P Y+ E LS +M Y +NFVK G
Sbjct: 198 RFMPPGAPLPWQ---GLKIARHLPPVCPQKLPDLSPH--GSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIP--TALTQFSTSLGPIVDGHVIPNQPYKVMGHYT--------EHFSRYDLLFGITESESYHTLAA-----------LALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVL--DILSDARVVGPLLQTGMFH------ADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTG 654
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Match: Nlg1 (gene:FBgn0051146 transcript:FBtr0081541) HSP 1 Score: 179.104 bits (453), Expect = 6.121e-46 Identity = 146/491 (29.74%), Postives = 230/491 (46.84%), Query Frame = 1
Query: 223 RFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWH-HIKRILPFLEHQDEECLTLNIYVP-ENNHTSP--FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMK-SDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS--------QFSHMYMNALGKYMNVS-SKLLFRQLKREPITNILKASEFTPKLKFSSRIGP-----TISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYV-YNQQSIYEI-----LYHLYTDWQKM--DPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP-------NHRKYSHME--LSRTMMKYLSNFVKFG 1554
RF PP A ++ G I PVCPQ LP+++ +N + H H+ R+LP+L + E+CL LN+YVP E ++P + VL+++HGESFE SGN YD S L+SYG++I +T+NYRLG+LGF++ S D NYA D AAL WI NI F GD+++VTLMGH + LFHR I+++G+ +S W+ S Q +H L +++ +L L+ +IL T +FS+ +GP I NQ + + + + D+L G+ + A L + L+E ++N + + QS ++I L +Q M +P+ E + + +++DA + P LQ H +D + Y+Y+F + + + ++L +FG P Y+ E LS +M Y +NFVK G
Sbjct: 198 RFMPPGAPLPWQ---GLKIARHLPPVCPQKLPDLSPH--GSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIP--TALTQFSTSLGPIVDGHVIPNQPYKVMGHYT--------EHFSRYDLLFGITESESYHTLAA-----------LALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVL--DILSDARVVGPLLQTGMFH------ADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTG 654
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Match: Nlg4 (gene:FBgn0083975 transcript:FBtr0301074) HSP 1 Score: 177.563 bits (449), Expect = 1.996e-45 Identity = 101/253 (39.92%), Postives = 142/253 (56.13%), Query Frame = 1
Query: 154 VRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNY-NSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP--FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDN----LAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD------------MKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS 855
V + G+ YA+ +NRF+P A ++ G I DK++PVCPQ LPN+ + + ++KR+LPFLE+Q E+CL LN++ P N + PV++FIHGESFE SGN YD S LASYG+++ +TLNYRLG+LGF+ ++ N NY D AAL WI NI KF GD N VTL GHG M + LFHR I+++G+ S W+ + ++ L K +N +
Sbjct: 67 VEVFLGVPYAT------PPTKQNRFSPTRAPAPWD---GIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCT 310 HSP 2 Score: 50.447 bits (119), Expect = 7.574e-6 Identity = 53/274 (19.34%), Postives = 109/274 (39.78%), Query Frame = 1
Query: 1042 DVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNI-----------------------HSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTPNHRKYSH---------MELSRTMMKYLSNFVKFG----XXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQS 1755
DVL G+ + + F+A + N F + ++ +++ Y Y+ I+ + + YTDW + + R+ + ++ +DA F+ P ++ +I S++ + G+ Y Y+F Q +DL +FG P +SH LS +M + +NF + G + + + N+F W Y ++Y+ +K ++++ +++ IW LIP+LH++
Sbjct: 429 DVLFGVVTGESIWRFSAHDI--QNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAAL-----SDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKP----RIKNHFRAHQLSIWLRLIPELHRA 691
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Match: nlgn2a (neuroligin 2a [Source:ZFIN;Acc:ZDB-GENE-090918-2]) HSP 1 Score: 199.134 bits (505), Expect = 5.158e-53 Identity = 200/772 (25.91%), Postives = 309/772 (40.03%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS---SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNC 2331
PV Y G+ YA+ + RF PP A ++E +FAPVCPQN LP + F + D +Y +++Q E+CL LN+YVP + PV+LFIHG S+ G+GN +D S LA+YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LF R I +G+ +S WS S Y L + + + + L L+R+ ++ + P ++ GP + ++VP + + + D+L+G+N F + S F + F+ Y Y + + E + +YTDW D E R + D ++ PA+ +H +D Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W ++ +KQY++ LK +R N +N+ W EL+P LH + E F + R + K P T+ P+ T +L +E+ + S T D+ E L T+ G + +N +A +Y K +R+ + LSP R N DL +S + L KH + P R +RP C
Sbjct: 70 PVEQYLGVPYAT------APIGDRRFQPPEAPGSWQEVRN---ATQFAPVCPQNVHGVLPEIMLPVWFTDSLDVAATY----------IQNQSEDCLYLNVYVPTEDDIRDRRKKPVMLFIHGGSYMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSISYQPLKYTKILARKVGCTYGETADLVDCLRRKNFRELVD-QDIQPA-RYHIAFGPVMDG-----------DVVPDDPEILMQQGEFLNYDLLIGVNQGEGLKFVDDGGTESEEGISAAAFDYTISNFVDNLYGYPKGKDILRETIKFMYTDWADRD------NGEMRRKTLLALFTDHQWVAPAIATAKLH------ADYQSPVYFYTFYHHCQTETRPEWADAAHGDEIPYVFGVPMIGATDLFPCNFSKNDIM-LSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKP----RIRDNYRANKVAFWLELVPHLHNLHE--------EVFSTATTRLPPGTARTPHWKGQGP-----------RTTRHPIPTFPSELDPDSSEQPRFPPFPSDT--RDYSTE------LSVTVAVGASLLFLNILAFAALYYKRDKRHEMRR-------HRLSPQRGVAAN----DLAHSQEEEIMSLQMKHSEHDAHHDMEP-----LRPHDILRPAC 749
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Match: nlgn3b (neuroligin 3b [Source:ZFIN;Acc:ZDB-GENE-060526-197]) HSP 1 Score: 197.593 bits (501), Expect = 2.245e-52 Identity = 180/653 (27.57%), Postives = 281/653 (43.03%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNS-PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPENNHT-----------------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
+NS+++ +V+LM +S++ L ++ GR L G+ + +++ PV Y G+ YA+ E RF PP A ++G +F PVCPQ + N D W +++ + +L+ Q E+CL +NIYVP + T P PV+LFIHG S+ G+GN D S LASYG +I ITLNYR+G+LGF+ + D A+GNY D AL+WI+ NI F GD +VT+ G G + LFHR II +G+ LS WS + +++ + +G + + L+ KR L E P +F GP I +L+P + + E D+++G+N F + + S F + +F+ Y Y + ++ E + +YTDW D E+R M D ++ PA+ ++H+ S T+ Y F D+ D+L +FG P N + M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W L+P LH F Y
Sbjct: 21 LNSALRWLLVWLM-WSVSVA-STLTYQPTVNTALGR-LRGMRVAVATEGLGPVDQYLGVPYAA------PPVGEKRFMPPDAP---SAWSGVRNATRFPPVCPQTVRNAV-----PDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTEDDGLRDSRDDPRPVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGDQAAKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWSVNYQPVKYTRLLAERVGCNVLDTQDLVLCMQKRS--YRELVEQEIQPA-RFHVAFGPVIDG-----------DLIPDDPEVLMEQGEFLNYDIMLGVNQGEGFRFVEGVVEPEEGGVSGSDFDFTVSDFVDSLYGYPEGKDTLRETIKFMYTDWADRD------NPETRRKTLVAMFTDHQWVEPAVVTADLHARYGS------PTFFYAFYHHCQSPMKPPWADSAHGDELPYVFGVPLIGPTELFPCNFSRNDIM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVTWAKYGPHDQLYLHIGLKP----RVRDHYRATKVAFWKHLVPHLYNLHDMFHY 625
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Match: nlgn4xa (neuroligin 4 X-linked a [Source:ZFIN;Acc:ZDB-GENE-100309-2]) HSP 1 Score: 194.512 bits (493), Expect = 2.094e-51 Identity = 173/623 (27.77%), Postives = 281/623 (45.10%), Query Frame = 1
Query: 28 VFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSW----SQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+ L +++I+ Q + ++G R L + +P + PV Y GI YA + T E RF PP + G +FAPVCPQ L + F N + ++ ++ +++ Q E+CL LNIYVP ++ PV+++IHG S+ G+GN D S LASYG +I +TLNYRLG+LGF+ + D A+GNY D AL+WI NI F GD +VT+ G G + LF + II +G LS W+ ++++ + +G M + S L L+ + +++ ++ + K+ GP I +++P + E D+++G+N GF F ++ + S F + +F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 27 IVLAAAWLAITWAQQHPIVTTNYGKLRGLKTPLPNEILG---PVEQYLGIPYA----LPPT--GERRFQPPEPPM---SWPGIRNATQFAPVCPQFLEDR--FLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDDIHDENGLRPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRILAEKVGCNM-LDSIDLVECLQNKNYKELIE--QYITQAKYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGFKFVDGIVDSEDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWSDSAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNINELFQY 603
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Match: nlgn4xb (neuroligin 4 X-linked b [Source:ZFIN;Acc:ZDB-GENE-100309-1]) HSP 1 Score: 192.971 bits (489), Expect = 4.804e-51 Identity = 198/736 (26.90%), Postives = 308/736 (41.85%), Query Frame = 1
Query: 112 LSGIPINLSSNS-PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPN---MTD-----FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP----FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK---LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQYPIDWHKRETFGINSNRKTFDND---FDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINT-LLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINN 2154
L G+ + L S PV + G+ YA E RF P + G +FAPVCPQ L + +TD F N D +Y H Q E+CL LNIYVP T PV+++IHG S+ G+GN D S LASYG +I +T+NYRLG+LGF+ + D A+GNY D AL+W+ NI F+GD +VT+ G G + LF + II +G LS W+ + Y L + + + L L+ + +++ + TP K+ GP I +++P + E D+++G+N G+ F +L + + F+ + EF+ Y Y + ++ E + +YTDW + E E R + D ++ PA+ ++H+ S TY Y F + D+ D+L +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY ++S K D F Y + + + ST + + P T ++ ++++K E T+ IIE+ +T L TI G + +N +A +Y K +L P N
Sbjct: 32 LRGLRVALPSEILGPVEQFLGVPYAMAPT------GERRFQAPEPPL---SWPGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYVHD----------QSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGSYVEGTGNMIDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRLLAEKVGCNEDDTLELIECLQSKNYKELIEQN-ITPA-KYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGYKFVDGILDSEDRVTSNDFEFAISEFVDHLYGYPEGKDTLRETIKFMYTDWA------DRENPEMRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSDMKPAWADSSHGDELPYVFGIPMIGPTDLFNCNFSKNDIM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKIAFWLELVPHLHNINELFQY-----------VSSTTKIPPQDTTPFSYTKRL---SNKLFPSTTRHPPA-PPANTKQM------SDQQKTSEHADGTV----IIEARDYSTELSVTIAVGASLLFLNILAFAALYYKKDKHRLESSRRLSPPRN 692
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Match: nlgn4xb (neuroligin 4 X-linked b [Source:ZFIN;Acc:ZDB-GENE-100309-1]) HSP 1 Score: 192.971 bits (489), Expect = 4.804e-51 Identity = 198/736 (26.90%), Postives = 308/736 (41.85%), Query Frame = 1
Query: 112 LSGIPINLSSNS-PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPN---MTD-----FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP----FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK---LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQYPIDWHKRETFGINSNRKTFDND---FDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINT-LLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINN 2154
L G+ + L S PV + G+ YA E RF P + G +FAPVCPQ L + +TD F N D +Y H Q E+CL LNIYVP T PV+++IHG S+ G+GN D S LASYG +I +T+NYRLG+LGF+ + D A+GNY D AL+W+ NI F+GD +VT+ G G + LF + II +G LS W+ + Y L + + + L L+ + +++ + TP K+ GP I +++P + E D+++G+N G+ F +L + + F+ + EF+ Y Y + ++ E + +YTDW + E E R + D ++ PA+ ++H+ S TY Y F + D+ D+L +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY ++S K D F Y + + + ST + + P T ++ ++++K E T+ IIE+ +T L TI G + +N +A +Y K +L P N
Sbjct: 32 LRGLRVALPSEILGPVEQFLGVPYAMAPT------GERRFQAPEPPL---SWPGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYVHD----------QSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGSYVEGTGNMIDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRLLAEKVGCNEDDTLELIECLQSKNYKELIEQN-ITPA-KYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGYKFVDGILDSEDRVTSNDFEFAISEFVDHLYGYPEGKDTLRETIKFMYTDWA------DRENPEMRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSDMKPAWADSSHGDELPYVFGIPMIGPTDLFNCNFSKNDIM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKIAFWLELVPHLHNINELFQY-----------VSSTTKIPPQDTTPFSYTKRL---SNKLFPSTTRHPPA-PPANTKQM------SDQQKTSEHADGTV----IIEARDYSTELSVTIAVGASLLFLNILAFAALYYKKDKHRLESSRRLSPPRN 692
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Match: jak1 (Janus kinase 1 (a protein tyrosine kinase) [Source:Xenbase;Acc:XB-GENE-483750]) HSP 1 Score: 193.741 bits (491), Expect = 5.134e-51 Identity = 165/590 (27.97%), Postives = 260/590 (44.07%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT----SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------------KKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQS--IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN +D S LASYG +I IT+NYRLG+LGF+ + D ++GNY D+ AL+W S NI F GD ++T+ G G K LF R I +G LS W+ S +++ + +G M+ S +L+ L+++P ++ + P +++ GP I +++P + E D+++G+N G F + + S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R + + +W EL+P+LH
Sbjct: 76 PVVQFLGVPYAA------PPIGERRFQPPEPPTMWGDIKN---STQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNMSDSGELV-ECLQKKPYRELVD-QDIQP-VRYHIAFGPVIDG-----------DVIPDDPQVLMEQGEFLNYDIMLGVN-QGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDWA------DRNNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADASHGDEIPYVFGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ATKVNLWLELVPRLH 614
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Match: nlgn4x (neuroligin 4 X-linked [Source:NCBI gene;Acc:100329189]) HSP 1 Score: 191.43 bits (485), Expect = 2.692e-50 Identity = 176/635 (27.72%), Postives = 286/635 (45.04%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVP-ENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSW----SQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELK-FQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + I L F + + + ++G R + +PI + PV Y G+ YAS E RF PP +TG +FAPVCPQ L D ++ W ++ ++ +++ Q+E+CL LNIYVP E++ P PV+++IHG S+ G+GN D S LAS+G +I IT+NYRLG+LGF+ + D A+GNY D AL+WI NI F GD +VT+ G G + LF + II +G LS W+ ++++ + + +G M + + L L+ + +++ S TP + GP I +++P + E D+++G+N F + ++ N D L F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + + D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 VNSNLLLWIAALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIEILG---PVEQYLGVPYAS------PPTGERRFQPPEPP---SSWTGIKNATQFAPVCPQFL----DERSLLNDMLPIWFTANLDTVVSYVQDQNEDCLYLNIYVPTEDDIHDPNNKKPVMVYIHGGSYMEGTGNMIDGSILASHGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCDM-LDTIDLVECLRDKNYKELIQQS-ITPA-TYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDG--MVDNEDGVSLSDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHARYGS------PTYFYAFYHHCQSEMKPTWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKPNRFEEVAWSKYDPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Match: ddx17 (DEAD-box helicase 17 [Source:Xenbase;Acc:XB-GENE-1000758]) HSP 1 Score: 190.274 bits (482), Expect = 7.245e-50 Identity = 162/580 (27.93%), Postives = 251/580 (43.28%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPENNH---TSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
PV Y G+ YA+ E RF PP ++G F+PVCPQN+ N D W ++ + +L+ Q E+CL LNIYVP + T PV+++IHG S+ GSGN D S LASYG ++ ITLNYR+G+LGF+ + D A+GNY D AL+W+S N+ F GD +++T+ G G + LF R II +G+ LS W+ + Y L + + NV + R+ L + P ++ GP I +++P + + E D+++G+N G F ++ + S F + F+ Y Y + ++ E + +YTDW D E+R + D ++ P++ ++H+ S TY Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W L+P LH F Y
Sbjct: 59 PVDQYLGVPYAA------PPVGEKRFLPPEPP---PSWSGIRNATHFSPVCPQNIQNAV-----PDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDDIRDTGAKPVMVYIHGGSYMEGSGNMIDGSVLASYGNVVVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENVAFFGGDPHRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPA-RYHVAFGPVIDG-----------DVIPDDPEILMEQGEFLNYDIMLGVN-QGEGLKFVENVVDAEDGVSGSDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRD------NPETRRKTLVALFTDHQWVEPSVVTADLHARYGS------PTYFYAFYHHCQSLMKPAWADAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP----RVRDHYRATKVAFWKHLVPHLYNLHDMFHY 594
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Match: jak1 (Janus kinase 1 (a protein tyrosine kinase) [Source:Xenbase;Acc:XB-GENE-483750]) HSP 1 Score: 186.037 bits (471), Expect = 2.049e-48 Identity = 165/610 (27.05%), Postives = 260/610 (42.62%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN------------------------HTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------------KKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQS--IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN +D S LASYG +I IT+NYRLG+LGF+ + D ++GNY D+ AL+W S NI F GD ++T+ G G K LF R I +G LS W+ S +++ + +G M+ S +L+ L+++P ++ + P +++ GP I +++P + E D+++G+N G F + + S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R + + +W EL+P+LH
Sbjct: 76 PVVQFLGVPYAA------PPIGERRFQPPEPPTMWGDIKN---STQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNMSDSGELV-ECLQKKPYRELVD-QDIQP-VRYHIAFGPVIDG-----------DVIPDDPQVLMEQGEFLNYDIMLGVN-QGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDWA------DRNNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADASHGDEIPYVFGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ATKVNLWLELVPRLH 634
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Match: jak1 (Janus kinase 1 (a protein tyrosine kinase) [Source:Xenbase;Acc:XB-GENE-483750]) HSP 1 Score: 186.037 bits (471), Expect = 2.420e-48 Identity = 165/610 (27.05%), Postives = 260/610 (42.62%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT------------------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------------KKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQS--IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN +D S LASYG +I IT+NYRLG+LGF+ + D ++GNY D+ AL+W S NI F GD ++T+ G G K LF R I +G LS W+ S +++ + +G M+ S +L+ L+++P ++ + P +++ GP I +++P + E D+++G+N G F + + S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R + + +W EL+P+LH
Sbjct: 76 PVVQFLGVPYAA------PPIGERRFQPPEPPTMWGDIKN---STQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNMSDSGELV-ECLQKKPYRELVD-QDIQP-VRYHIAFGPVIDG-----------DVIPDDPQVLMEQGEFLNYDIMLGVN-QGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDWA------DRNNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADASHGDEIPYVFGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ATKVNLWLELVPRLH 634
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Match: Nlgn1 (neuroligin 1 [Source:MGI Symbol;Acc:MGI:2179435]) HSP 1 Score: 194.512 bits (493), Expect = 2.204e-51 Identity = 168/580 (28.97%), Postives = 257/580 (44.31%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT----SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD-----------MKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 605
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Match: Nlgn1 (neuroligin 1 [Source:MGI Symbol;Acc:MGI:2179435]) HSP 1 Score: 194.512 bits (493), Expect = 2.204e-51 Identity = 168/580 (28.97%), Postives = 257/580 (44.31%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHT----SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD-----------MKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 605
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Match: Nlgn1 (neuroligin 1 [Source:MGI Symbol;Acc:MGI:2179435]) HSP 1 Score: 186.422 bits (472), Expect = 1.191e-48 Identity = 171/609 (28.08%), Postives = 260/609 (42.69%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN------HT------------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + HT P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 634
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Match: Nlgn1 (neuroligin 1 [Source:MGI Symbol;Acc:MGI:2179435]) HSP 1 Score: 186.422 bits (472), Expect = 1.191e-48 Identity = 171/609 (28.08%), Postives = 260/609 (42.69%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN------HT------------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + HT P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 634
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Match: Nlgn3 (neuroligin 3 [Source:MGI Symbol;Acc:MGI:2444609]) HSP 1 Score: 173.326 bits (438), Expect = 2.710e-44 Identity = 159/607 (26.19%), Postives = 250/607 (41.19%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTD-------FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN-----------------------HTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
PV Y G+ YA+ E RF PP ++G F PVCPQN+ F N D +Y ++ +E+CL LN+YVP + + PV+++IHG S+ G+GN D S LASYG +I ITLNYR+G+LGF+ + D A+GNY D AL+W+S NI F GD ++T+ G G + LF R II +G+ LS W+ + +++ + + +G NV + R+ L + P ++ GP I +++P + + E D+++G+N G F ++ + S F + F+ Y Y + ++ E + +YTDW D E+R + D ++ P++ ++H+ S TY Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W L+P LH F Y
Sbjct: 62 PVDQYLGVPYAA------PPIGEKRFLPPEPP---PSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATY----------IQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVG--CNVLDTVDMVDCLRQKSAKELVEQDIQPA-RYHVAFGPVIDG-----------DVIPDDPEILMEQGEFLNYDIMLGVN-QGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRD------NPETRRKTLVALFTDHQWVEPSVVTADLHARYGS------PTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKP----RVRDHYRATKVAFWKHLVPHLYNLHDMFHY 617
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Match: sp|Q8N0W4|NLGNX_HUMAN (Neuroligin-4, X-linked OS=Homo sapiens OX=9606 GN=NLGN4X PE=1 SV=1) HSP 1 Score: 190.274 bits (482), Expect = 3.674e-49 Identity = 172/635 (27.09%), Postives = 278/635 (43.78%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLK---FSSRIGPTISNQLF--TYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + + L F I + + ++G R L + +P + PV Y G+ YAS E RF PP +TG +FA VCPQ+L D + W ++ ++ +++ Q+E+CL LNIYVP ++ S PV+++IHG S+ G+GN D S LASYG +I IT+NYRLG+LGF+ + D A+GNY D AL+WI N+ F GD +VT+ G G + LF + II +G LS W+ +N R L + N+L ++ L+ + I TI+ + + + +++P + E D+++G+N G F ++ + + F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 LNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILG---PVEQYLGVPYAS------PPTGERRFQPPEPP---SSWTGIRNTTQFAAVCPQHL----DERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA---------------VNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Match: sp|Q8NFZ3|NLGNY_HUMAN (Neuroligin-4, Y-linked OS=Homo sapiens OX=9606 GN=NLGN4Y PE=2 SV=1) HSP 1 Score: 187.963 bits (476), Expect = 2.249e-48 Identity = 173/635 (27.24%), Postives = 276/635 (43.46%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNS-PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPENN----HTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLK---FSSRIGPTISNQLF--TYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQY 1764
+NS++ + I L F I + + ++G + G+ L S PV Y G+ YAS E RF PP + +TG +F+ VCPQ+L D + W + ++ +++ Q+E+CL LNIYVP + S PV+++IHG S+ G+GN D S LASYG +I IT+NYRLG+LGF+ + D A+GNY D AL+WI N+ F GD +VT+ G G + LF + II +G LS W+ +N R L + N+L ++ LK + I TI+ + + + +++P + E D+++G+N G F ++ + + F + F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH + FQY
Sbjct: 21 LNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGK---IQGLRTPLPSEILGPVEQYLGVPYAS------PPTGERRFQPPESP---SSWTGIRNATQFSAVCPQHL----DERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA---------------VNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Match: sp|Q99K10|NLGN1_MOUSE (Neuroligin-1 OS=Mus musculus OX=10090 GN=Nlgn1 PE=1 SV=2) HSP 1 Score: 186.422 bits (472), Expect = 8.334e-48 Identity = 171/609 (28.08%), Postives = 260/609 (42.69%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN------HT------------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + HT P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 634
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Match: sp|Q9XTG1|NLGN1_CAEEL (Neuroligin-1 OS=Caenorhabditis elegans OX=6239 GN=nlg-1 PE=1 SV=1) HSP 1 Score: 185.267 bits (469), Expect = 1.411e-47 Identity = 159/588 (27.04%), Postives = 271/588 (46.09%), Query Frame = 1
Query: 148 PPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQ-NLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP---FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFM-KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK--------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSK-----------LLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMIN---DAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQI---SYKRDNSVYDAQFSDDLM-MLFGTP------NHRKYSHME-----LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQ-FSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
PPV Y GI Y G Y RFN +++ + D K +PVC Q ++P +++ K + R+LP L+ Q E+CL +NIYVPE S PV++ +HGE + G+GNA++ + LA+YG II +TLNYRLG+ GF+ + + + GN D+ +AL ++ + F GDS VTL G G ++LF R I+++G+ LS W+ SQ Y L + + + K + R ++ NI KA F S P + QL ++S +RE+D+LVG++ + + ++ N D S+ K + ++ Y ++++ I + + YTDW E+ R+ + S+ N ++N D + P ++ HS+ + + + T+++ F+ + S ++ NS S D++ +FG P R YS +S+ MM Y+SNFVK G+P++P P F WPQ+ ++ L+ + + V++ + + W+ IP+LH+
Sbjct: 43 PPVAQYLGIPY---GVAPTGQY---RFNMAISAAKWTHMPKD--ARKVSPVCIQTDMPELSETKAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGWGTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGRCESSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQPGRRLFRRAILLDGSALSPWAISQNPQQYFMQLAEELACAPKNRTSSFNDNVDTIVRCMQVHSSENITKAVLKIDVPTFLSGFAPIVDGQLIPNKPQVS--FSTQYGSLFREIDLLVGISSNPSHH------MISNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDW-------ENPRDHPK-SIRNGVLNALSDVLYTAPLIETLRSHSADEVR--KEANTFMFAFAHETRSWSQEQPNSGIRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNFPMGDVFHSTAWPQFDQPNREAY---LEITDRPRVKNYYRNAQVGFWNNFIPQLHK 601
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Match: sp|Q62765|NLGN1_RAT (Neuroligin-1 OS=Rattus norvegicus OX=10116 GN=Nlgn1 PE=1 SV=1) HSP 1 Score: 185.652 bits (470), Expect = 1.840e-47 Identity = 169/609 (27.75%), Postives = 258/609 (42.36%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN-----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN------------------------HTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG--------------------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYM--NVSSKL-LFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV + G+ YA+ E+RF PP + + +FAPVCPQN LP + F N D +SY ++ Q E+CL LNIYVP + P PV+++IHG S+ G+GN YD S LASYG +I IT+NYRLG+LGF+ + D A+GNY D+ AL+W S NI F GD ++T+ G G + K LF R I +G LS W+ S Y L + NVS + L L+++P ++ + P ++ GP I +++P + E D+++G+N G F ++ ++ S F + F+ Y Y + + E + +YTDW + E+R + D ++ PA+ ++HS+ S TY Y F + + DA D++ + G P N K M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK K R +N+ +W EL+P LH
Sbjct: 76 PVIQFLGVPYAA------PPTGEHRFQPPEPPSPWSDIRN---ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSY----------VQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVD-QDVQPA-RYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWA------DRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGS------PTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYR----ANKVNLWLELVPHLH 634
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Match: K1QS61 (Neuroligin-4, X-linked OS=Crassostrea gigas OX=29159 GN=CGI_10007156 PE=4 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 6.028e-73 Identity = 197/604 (32.62%), Postives = 305/604 (50.50%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILP------------FLEHQDEECLTLNIYVP--ENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-------------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSS-----KLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVY----DAQFSDDLMMLFG-------TPNHRKYSHME--LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDN 1827
PV Y G+ Y SLGK ++ TE S FY ++ I D++A VCPQ ++ KD + ++LP + ++Q E+CLTLN+++P E T+PF V++F+HGES+EIG+GNAYD S LASYG +I IT+NYRLG+LGF+ + + AQGN A DI A LQW+ NI FNGD NKVTL GHGH K K F R +I +G+ LS W+ S ++ L + +N SS + L + LK +++ +S PK P ++F + NL+ +++ + + V+ G+ + A + L + SE + ++ F+ N+ YN+Q IYEILYH YT W + F +R ++++D ++ P ++ HS + TYLY F+ + D ++Y A D+L +FG TP K++ +E +S TMM+Y +NF K G+PN+P+ +E + S WP+Y ++++++F T+S R E +W +LIPKL+Q + D + E N N TFD+
Sbjct: 53 PVELYRGLSYGSLGK-QDQATTE--------SNFYSQWNKTLIVDQWAKVCPQE--DIGGVKSLKD--------LLKVLPRVHVIRLYHRSNYTKNQVEDCLTLNVFLPAREWTDTTPFAVMVFVHGESYEIGTGNAYDGSVLASYGDVIVITINYRLGVLGFLNTGHSSAQGNQALMDILAVLQWVQDNIAAFNGDPNKVTLFGHGHGAALVNILMFSSLTEKGKYFQRAVIQSGSALSRWAVSYDAYSCAQWLARNVNCSSFTNDIEGLTKCLKSRSAQDLVNSSPGAPKYYSCMAPSPNPYGEIFRAPVE---NLMSESRNTFTSIPVIFGVTSNEAYMYLKQKEL--TDGISEDRKSKIIRTFVLNNFQYNRQKIYEILYHQYTSWDTIQDDF------TRRDNVLQLLSDGLYVAPLVKMTQQHSLSTD-------TYLYAFTH--ATVSDTALYHNWTSAVHGDELAYIFGAPLVEGVTPFSEKFTPLEKTISETMMRYWTNFAKTGDPNKPEGELAFEQKLR-SDPGWPKYDRNQQRFLHFGSNTTSSSHYR----GKELSLWLDLIPKLNQPGKPNPDPREHELKDQN-NMATFDD 611
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Match: A0A1S3KAM1 (neuroligin-4, X-linked isoform X1 OS=Lingula unguis OX=7574 GN=LOC106180277 PE=4 SV=1) HSP 1 Score: 261.922 bits (668), Expect = 4.629e-71 Identity = 197/610 (32.30%), Postives = 296/610 (48.52%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPEN--NHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK---------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-----SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFS------KQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX--------XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDND 1830
PV YFG++YASL ++RF V S E++ G I VCPQ + + K + H R++PFLE Q EECL LNIYVP+ N T+P PV+++IHG+S+ +GSGNAYD S LASYG +I ITLN+RLG+LGF+ S D A GNYA +DI AAL WI NI F GD+ +VTL GHG+ K LF R I ++G+ LS W S+ Y L + +N S S L LK P+ +L+A P K+ + GP + +S +L+ +N+ ++D+L G+ N G F N F +EL ++ +++ Y Y++Q IY+IL H Y+DW + E E R +++ D F+ P + F H+ TY Y F+ + + + NSV+ D+L+ +FG P ++ + M LS +M+Y +NF K GNPN+ ++S + W Y TE+ Y+ F ++ +R++ + +W ELIPK++ S +H + + N +TF+ D
Sbjct: 79 PVEAYFGLQYASLQG------GDHRFM--VCSSPTEKWDGTRIVYGKRAVCPQRAIDEAELRKTMPY--ARVQHFLRLMPFLEDQTEECLNLNIYVPQRVKNDTTPLPVMVYIHGDSYSVGSGNAYDGSVLASYGGVIVITLNFRLGILGFLSSGDAEAPGNYAIWDIQAALVWIKNNIEPFGGDAQRVTLFGHGYGAALLNILMVSPVSRLQGKPLFQRAITLSGSALSTWGLSRHPFHYTLKLAERVNCSHAVQNSAELVACLKNTPVEELLEAE--MPAHKYFTSFGPVVDGMAILPSS--VEDLMTNNRGL-SQIDLLTGVV-KNEGLVF-----CDQNQFEKGITELTQMKIVRTYVRNVYDYHKQKIYDILLHQYSDWDRP------EDNEIRRDNTMELLGDGQFVAPTIDFAKRHAGLNR------STYFYTFNYPTVRLEGSTRRWANSVH----GDELLYIFGAPVANGVEPFADSYGRQDRM-LSEAVMRYWTNFAKTGNPNDSGVQSSTWSPDLQNRRKGKRYSNEIWVPYDATER-YIEFAMRP----RIRTHYKGAKMALWLELIPKIYNSDDLDPVYHLLDNYDRN---ETFEQD 642
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Match: A0A2C9KC18 (COesterase domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106056486 PE=4 SV=1) HSP 1 Score: 260.766 bits (665), Expect = 2.255e-70 Identity = 241/784 (30.74%), Postives = 373/784 (47.58%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVP--ENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG---------------HDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-----SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISN-QLFTY-ASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQK-MDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMF--SKQISYKRDNSVYDAQ--FSDDLMMLFGTPN-------HRKYSHME--LSRTMMKYLSNFVKFGXXXXXXXXXX---XXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDF----DYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDL------------SITKNEEKKIEESVSSTIKED--FIIESIKINTLLWTILA--GVAFFLINSI--AIMCIYMN-IRKLKLLRQNIRGP---INNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATS 2301
PV YFG+RY L RF PP E++ G + K PVCPQ + + ++ K + H++ I P+L Q E+CLTLN++VP E N T+P V++F+HGES++ G+GNAY+ S LAS+G +I +TLNYRLG+LGF+ + D A GNYA D+ AL W+ NI FNGD +VTL GHG +D++ +F R II +G+ S W+ S L +N S +K L L+ ++ ++ P K+ S P+I + + T+ KL R P++K + + V+ G+ + A + N + K SE + ++ +++ + Y++Q IY IL HLYTDW + DP + +R S+ ++++D F+ P +Q NIHS T TYLY F S Q + +N D Q D+L +FG+P Y++ E LS +M Y +NF K GNPN+P+ ++ N+F WP+YT +++Y L + VRS+ + + W +LIPK+ +S H E + N TFD+ +++ F P M +S P T D+ S E KK + S +T + D F +S + +I+ G + LIN+I A +C IRK++LL + + GP I+ +LE + P + SG+ E L+S S +ATS
Sbjct: 64 PVEAYFGLRYGDLDG------GGMRFMPPKNP--KEQWNGIRVAMKHQPVCPQPVKHEQEYSKQLPE--ARVAHLRNITPYLTDQKEDCLTLNLFVPKQEWNDTAPMAVMVFVHGESYQTGTGNAYEGSVLASFGDVIVVTLNYRLGVLGFLSTGDQSAMGNYALLDVIQALLWLKENIPSFNGDPQRVTLFGHGTGAAIVNLLLLSPFVYDLRGNIFQRAIIQSGSASSTWAMSYDPKWCTEKLAIKVNCSRHIANTKDLVHCLRERSDVTLVNSTPNAP--KYYSCFAPSIDSWTVLTHEVDKLLRE--PNSK--FSTVPVMFGVTKNEAYAYLNQDDIRKG--ISEFRKAQIIRTYVQNVFRYHRQKIYAILDHLYTDWTRPPDP------KSNRDSIL-ELLSDGQFVAPLVQMANIHSET-------ADTYLYSFAYSTQSETQNENE-EDVQGIHGDELPYVFGSPLVDGVSPFPTSYTNAERMLSEAVMTYWTNFAKTGNPNDPRNQTSVFGEKVSNRFVDLKWPKYTKDKQEY----LPIGRRPVVRSHYRALKMAAWLDLIPKIDKSDGGDQSSHLLEQ---SDNMSTFDDPLHLIPNFDGIFPSPPPMPPVRPTPMPSSDVPWTTHYPDVTEDNPLPKDMKASSQAAESKKDQHSGETTAEPDKGFTYKSSAGAGVPLSIVVAIGGSLLLINAIIFAGLCYQRERIRKMRLLSKPLSGPDMDIDEIRLNRKLESNRSSPCPMGSSGN--------APECISLMSGASAHQHATS 799
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Match: G7YM23 (Neuroligin-4 X-linked protein OS=Clonorchis sinensis OX=79923 GN=CLF_111845 PE=4 SV=1) HSP 1 Score: 256.529 bits (654), Expect = 2.169e-68 Identity = 212/737 (28.77%), Postives = 319/737 (43.28%), Query Frame = 1
Query: 88 IDFGDGRFLSGIPINLSSNS-PPVRGYFGIRYASLGKIKNTVY--------------------TENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNY-NSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSP----FPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK---------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFR---QLKR-----EPI-----------------------TNILKASEFTPKLKFSS-------------------------------RIGPTISNQLFTYASKLSRNLVPSNK-----------DFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQ-----KMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHS------STKSQSDNQGKTYLYMFSKQISYKRDNSV----------YDAQFSDDLMMLFGTP------------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNF-------DLKTSS-KMSVRSNLASNEYRIWDELIPKL-----HQSFQYPIDWHKRETFGINSNRKT 1818
+ DG+ L+G+ I+L S PPV Y GIRYASLG K T+Y + +RF+ VASFFYE TG + PVCPQ P + D + Y +KRI PFL HQ E+CLTLNIYVP + PV+LF+HGES+E GSGNAYD+S LA + + IT NYRLGLLGF+ D + GN+A +D+ AAL WI TNI +F GD ++TLMG+GH + R+I++NG+GL+ W+ S + M L K +N++ + Q+KR PI N KA T K K S R+GP +S LFT ++ PS K + ++D+++G A F++ +S L + F+ Y NQQ I ++L ++Y ++ D EH + +++ +++D F+ PA Q ++H S +S+ KT+L F+ S + D S + F +DL + G P + +Y +S+ M+ Y+SNF+ G + ++ S +YWP+Y K Y+N D+K++ ++ + IW EL+P+L PI H+R + I ++ T
Sbjct: 37 VQLADGKKLTGLAIHLPVASIPPVHAYLGIRYASLGG-KQTMYFSARPSHRTSEDGKKVDFVPSPHRFSHSVASFFYESPTGTHSKTVLPPVCPQ--PPI-DLKMVEAEYLGPQRDRLKRIAPFLYHQTEDCLTLNIYVPNPAQSQSDYKRHPVVLFVHGESYEYGSGNAYDLSVLAGFTGAVCITFNYRLGLLGFLSLKDGQSNGNFALFDLQAALLWIRTNIARFGGDPEQITLMGYGHGAALIHLFSLSKLSQGFGAQGIRRIILLNGSGLASWATSGLEELVMRELAKQLNITEAVELENSSQVKRTDNQPAPILSDSSKPTQSKTPSEVFQANTASANQTKAPNNTTKPKRPSLSQLLVKRLKELSFDNLVRLQKNLTSLPCTERLGPVVSKHLFTGLLSSDQHAKPSEKTESNKNGKPWTSLFSKVDLMIGFVKQAADRFYSRAETHGIQSWSLL----RCLHFV---YPQNQQVISDVLQYMYKNFPMQNVGNTDASLEH--PDHQLAQMLTILSDGFYRAPAFQTASLHRKLSDTVSPESKVTGSRKTFLASFT-HPSTRADQSGTSELWSKKVWHGPGFGEDLAYILGAPLVSPNRVDPFDGTYSRYD-ATISQNMLNYISNFINTG----NPNKSLRKDNSENSSNYWPEYDDHTKVYLNIGSRNSRSDVKSADFPCTIEHGSQDKKLSIWAELLPRLAGLPTKTKPHNPIQKHERHSEAIEEHQNT 754
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Match: A0A1S3KB75 (neuroligin-4, X-linked isoform X2 OS=Lingula unguis OX=7574 GN=LOC106180277 PE=4 SV=1) HSP 1 Score: 253.062 bits (645), Expect = 5.126e-68 Identity = 194/610 (31.80%), Postives = 294/610 (48.20%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPEN--NHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK---------------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-----SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDF----SELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFS------KQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYT--VTEKQYVNF------DLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDND 1830
PV YFG++YASL ++RF V S E++ G I VCPQ + + K + H R++PFLE Q EECL LNIYVP+ N T+P PV+++IHG+S+ +GSGNAYD S LASYG +I ITLN+RLG+LGF+ S D A GNYA +DI AAL WI NI F GD+ +VTL GHG+ K LF R I ++G+ LS W S+ Y L + +N S S L LK P+ +L+A P K+ + GP + +S +L+ +N+ ++D+L G+ N G F N F +EL ++ +++ Y Y++Q IY+IL H Y+DW + E E R +++ D F+ P + F H+ TY Y F+ + + + NSV+ D+L+ +FG P ++ + M LS +M+Y +NF K G P + Q S+ P+ T +++ F L+ + + +R++ + +W ELIPK++ S +H + + N +TF+ D
Sbjct: 79 PVEAYFGLQYASLQG------GDHRFM--VCSSPTEKWDGTRIVYGKRAVCPQRAIDEAELRKTMPY--ARVQHFLRLMPFLEDQTEECLNLNIYVPQRVKNDTTPLPVMVYIHGDSYSVGSGNAYDGSVLASYGGVIVITLNFRLGILGFLSSGDAEAPGNYAIWDIQAALVWIKNNIEPFGGDAQRVTLFGHGYGAALLNILMVSPVSRLQGKPLFQRAITLSGSALSTWGLSRHPFHYTLKLAERVNCSHAVQNSAELVACLKNTPVEELLEAE--MPAHKYFTSFGPVVDGMAILPSS--VEDLMTNNRGL-SQIDLLTGVV-KNEGLVF-----CDQNQFEKGITELTQMKIVRTYVRNVYDYHKQKIYDILLHQYSDWDRP------EDNEIRRDNTMELLGDGQFVAPTIDFAKRHAGLNR------STYFYTFNYPTVRLEGSTRRWANSVH----GDELLYIFGAPVANGVEPFADSYGRQDRM-LSEAVMRYWTNFAKTG--------NPNQPLPQTSVHGGPEMPNRFTGLKWLPFHPSNLLSLRIAMRPRIRTHYKGAKMALWLELIPKIYNSDDLDPVYHLLDNYDRN---ETFEQD 639
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Match: nlgn3b (neuroligin-3-like [Source:NCBI gene;Acc:103045798]) HSP 1 Score: 200.29 bits (508), Expect = 1.719e-53 Identity = 169/588 (28.74%), Postives = 256/588 (43.54%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPE---------NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
PV Y G+ YA+ E RF PP A ++G +F+PVCPQ + N D W +++ + +L+ Q E+CL LNIYVP N P PV+LFIHG S+ G+GN D S LASYG +I ITLNYR+G+LGF+ + D A+GNY D AL+WIS NI F GD +VT+ G G + LFHR II +G+ LS WS + +++ + +G + + L+ KR L + P +F GP I +L+P + + E D+++G+N F + + S F + +F+ Y Y + ++ E + +YTDW D E+R M D ++ PA+ ++H+ S T+ Y F + D+ D++ +FG P N + M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK VR + + + W L+P LH F Y
Sbjct: 69 PVDQYLGVPYAA------PPVGEKRFMPPDAP---SAWSGVRNATRFSPVCPQTVRNAV-----PDIMMPIWATYNLDTVATYLQEQSEDCLYLNIYVPTQTFYTHAYTNAREDPRPVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGDQAAKGNYGLLDQIQALRWISKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWSVNYQPVKYTRLLAERVGCNVLDTHDLVLCMQKRS--YRELVEQDIQPA-RFHIAFGPVIDG-----------DLIPDDPEVLMEQGEFLNYDIMLGVNQGEGLRFVEGVVEPEEGGVSGSDFDFAVSDFVDGLYGYPEGKDTLRETIKFMYTDWADRD------NPETRRKTLVAMFTDHQWVEPAMVTADLHARYGS------PTFFYAFYHHCQSPMKPAWADSAHGDEIPYVFGIPLIGPTELFPCNFSRNDIM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVSWSKYSPHDQLYLHIGLKP----RVRDHYRATKVAFWKHLVPHLYNLHDMFHY 611
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Match: nlgn3b (neuroligin-3-like [Source:NCBI gene;Acc:103045798]) HSP 1 Score: 197.593 bits (501), Expect = 1.692e-52 Identity = 169/596 (28.36%), Postives = 257/596 (43.12%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYW--HHIKRILPFLEHQDEECLTLNIYVPENNHT-----------------SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHG-----------HDMKKKLFHRLIIINGNGLSGWSWS----QFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
PV Y G+ YA+ E RF PP A ++G +F+PVCPQ + N D W +++ + +L+ Q E+CL LNIYVP + T P PV+LFIHG S+ G+GN D S LASYG +I ITLNYR+G+LGF+ + D A+GNY D AL+WIS NI F GD +VT+ G G + LFHR II +G+ LS WS + +++ + +G + + L+ KR L + P +F GP I +L+P + + E D+++G+N F + + S F + +F+ Y Y + ++ E + +YTDW D E+R M D ++ PA+ ++H+ S T+ Y F + D+ D++ +FG P N + M LS +M Y +NF K G+PN+P P N+F W +Y+ ++ Y++ LK VR + + + W L+P LH F Y
Sbjct: 69 PVDQYLGVPYAA------PPVGEKRFMPPDAP---SAWSGVRNATRFSPVCPQTVRNAV-----PDIMMPIWATYNLDTVATYLQEQSEDCLYLNIYVPTQSGTKKAGGESDDDGLREAREDPRPVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGDQAAKGNYGLLDQIQALRWISKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWSVNYQPVKYTRLLAERVGCNVLDTHDLVLCMQKRS--YRELVEQDIQPA-RFHIAFGPVIDG-----------DLIPDDPEVLMEQGEFLNYDIMLGVNQGEGLRFVEGVVEPEEGGVSGSDFDFAVSDFVDGLYGYPEGKDTLRETIKFMYTDWADRD------NPETRRKTLVAMFTDHQWVEPAMVTADLHARYGS------PTFFYAFYHHCQSPMKPAWADSAHGDEIPYVFGIPLIGPTELFPCNFSRNDIM-LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVSWSKYSPHDQLYLHIGLKP----RVRDHYRATKVAFWKHLVPHLYNLHDMFHY 619
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Match: nlgn4xa (neuroligin-4, X-linked [Source:NCBI gene;Acc:103022482]) HSP 1 Score: 194.897 bits (494), Expect = 1.212e-51 Identity = 205/788 (26.02%), Postives = 336/788 (42.64%), Query Frame = 1
Query: 7 SSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSW----SQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKED--FIIESIK--INTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDL 2226
S I + + L ++ + Q + ++G R L + +P + PV Y GI YA + T E RF PP + G +FA VCPQ L + F N + ++ ++ +++ Q E+CL LNIYVP ++ PV+++IHG S+ G+GN D S LASYG +I +TLNYRLG+LGF+ + D A+GNY D AL+WI NI F GD +VT+ G G + LF + II +G LS W+ ++++ M +G M + + L L+++ +++ ++ + K+ GP I +++P + E D+++G+N GF F ++ + S F + +F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH FQY +++ K I P D K T P T +S N ++ ++ S + +D +IE+ + L TI G + +N +A +Y K + N RGP SP R N P ++ + +D+
Sbjct: 25 SRIVVLVACLATSCLAAAQAQQHPIVTTNYGKLRGLKTALPNEILG---PVEQYLGIPYA----LPPT--GERRFQPPEPPM---SWPGIRNATQFAAVCPQFLEDR--FLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDDIHDENGLRPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRMLAEKVGCNM-LDTIDLVECLQKKNHKELIE--QYITQAKYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGFKFVDGIVDSEDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTDLFNCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNINDLFQY-----------VSTTTK------------IPPQDTTPFPYTKRLGKTWPSTTRHPGVS-QPNPKQTTDQRKGSDLGDDSAVVIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDK-RRHESNRRGP-----SPQR----NSTPANVAANANDI 732
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Match: nlgn4xa (neuroligin-4, X-linked [Source:NCBI gene;Acc:103022482]) HSP 1 Score: 191.43 bits (485), Expect = 2.219e-50 Identity = 205/797 (25.72%), Postives = 337/797 (42.28%), Query Frame = 1
Query: 7 SSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFL-SGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPE----NNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGH--------------------DMKKKLFHRLIIINGNGLSGWSW----SQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH---QSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKED--FIIESIK--INTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDL 2226
S I + + L ++ + Q + ++G R L + +P + PV Y GI YA + T E RF PP + G +FA VCPQ L + F N + ++ ++ +++ Q E+CL LNIYVP ++ PV+++IHG S+ G+GN D S LASYG +I +TLNYRLG+LGF+ + D A+GNY D AL+WI NI F GD +VT+ G G + + LF + II +G LS W+ ++++ M +G M + + L L+++ +++ ++ + K+ GP I +++P + E D+++G+N GF F ++ + S F + +F+ Y Y + ++ E + +YTDW + E E+R + D ++ PA+ ++H+ S TY Y F + S D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK VR + + + W EL+P LH FQY +++ K I P D K T P T +S N ++ ++ S + +D +IE+ + L TI G + +N +A +Y K + N RGP SP R N P ++ + +D+
Sbjct: 25 SRIVVLVACLATSCLAAAQAQQHPIVTTNYGKLRGLKTALPNEILG---PVEQYLGIPYA----LPPT--GERRFQPPEPPM---SWPGIRNATQFAAVCPQFLEDR--FLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDDIHDENGLRPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEGDRWFESRSYLFQKAIIQSGTALSSWAVNYQPAKYTRMLAEKVGCNM-LDTIDLVECLQKKNHKELIE--QYITQAKYHIAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDIMLGVN-QGEGFKFVDGIVDSEDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTDLFNCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP----RVRDHYRATKVAFWLELVPHLHNINDLFQY-----------VSTTTK------------IPPQDTTPFPYTKRLGKTWPSTTRHPGVS-QPNPKQTTDQRKGSDLGDDSAVVIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDK-RRHESNRRGP-----SPQR----NSTPANVAANANDI 741
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Match: nlgn2b (neuroligin 2b [Source:ZFIN;Acc:ZDB-GENE-090918-3]) HSP 1 Score: 191.43 bits (485), Expect = 2.537e-50 Identity = 191/715 (26.71%), Postives = 296/715 (41.40%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTD-------FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS---SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLN-GDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNI-RKLKLLRQNIRGPINNSLSPLR 2172
PV Y G+ YA+ E RF PP A +++ +FAPVCPQN+ + F N D +Y +++Q E+CL LN+YVP + PV+LFIHG S+ G+GN +D S LA+YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LF R I +G+ +S WS + Y L K + S + L L+R+ ++ + P +R + ++ +F D+L+G+N G+ F ++ + S F + F+ Y Y + + E + +YTDW D + R + D ++ PA+ +H ++ Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W +++ +KQY++ LK VR N +N+ W EL+P LH H+ IN+ + K VP P ST ST P D +E +I +T D+ E L T+ G + +N +A +Y ++ +LL++ R LSP R
Sbjct: 70 PVDEYLGVPYAT------APVGERRFQPPEAPGSWQDIRN---ATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAY----------VQNQSEDCLYLNVYVPTEDDIRDRRKKPVMLFIHGGSYMEGAGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDQERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLDYTKILAKKVGCSNSDTADLVDCLRRKSFRELVD-QDIQP-----ARYHIAFGPVVDGDVVPDDPEILMQQGEFL-NYDILLGVNQGEGLKFVDDSE---GEDGISAASFDYTISNFVDNLYGYPDGKDILRETIKFMYTDWADRD------NGDMRRKTLLALFTDHQWVAPAVATAKLH------AEFQSPVYFYTFHHHCQTEARPEWADAAHGDEIPYVFGVPMVGATDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNVPVPQDTKFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKP----RVRDNYRANKVAFWLELVPHLHT-------LHEEFFNSINTRTPPGSGGGRFPGKVPVP-GPGTRSTRHPVVSTYP-----PDPDPEGSERPRISPFPEAT--RDYSTE------LSVTVAVGASLLFLNVLAFAALYYKRDKRHELLQRRHR-----RLSPQR 712
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002735.1 (pep scaffold:Pmarinus_7.0:GL485913:3796:8263:-1 gene:ENSPMAG00000002501.1 transcript:ENSPMAT00000002735.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 125.561 bits (314), Expect = 1.137e-32 Identity = 79/253 (31.23%), Postives = 120/253 (47.43%), Query Frame = 1
Query: 163 YFGIRYASLGKIKNTVYTENRFN---PPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHI-KRILPFLE-HQDEECLTLNIYVPENNHTS------PFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLG-FMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNV 852
+ G+ YA E RF+ PP ++G+ P CPQ +PN + W +R+ +L Q EECL L++Y+P + S P V++F+HG SF G+G YD S LA++G +I + + YRLG+LG F + D+LA+GNY D AL+W+ N+ F GD +VTL+G G + LF R+I +G LS W+ + + AL + +
Sbjct: 4 FLGVPYA------RAPRGERRFSAAEPPAV------WSGEREAATRGPPCPQPVPNHRGW-----GMLPVWEAGNERLATWLSSKQSEECLNLDVYIPGRDGESIPGERPPLAVMVFLHGGSFLDGAGGLYDGSALAAHGDVIVVIVTYRLGVLGSFFSTGDSLARGNYGLLDQVMALRWVRENVGHFGGDQGRVTLVGAGTGAACASLLALSHHAEGLFQRVIAQSGTALSSWALNHRPELSAAALARSVGC 239
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007813.1 (pep scaffold:Pmarinus_7.0:GL477731:150595:158527:1 gene:ENSPMAG00000007070.1 transcript:ENSPMAT00000007813.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 102.449 bits (254), Expect = 4.868e-24 Identity = 66/204 (32.35%), Postives = 103/204 (50.49%), Query Frame = 1
Query: 112 LSGIPINLSSNSPPVRGYFGIRYAS--LGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTL 717
L G+ INL V + GI YA +G + RF PV E++ G + F+P C Q + + K +H DE+CL LN+++PE + V+++IHG ++ G+ Y+ LA+ G I+ +T+NYRLG LG++ + D ++GNY +D AAL W+ NI F GD+N+VT+
Sbjct: 51 LQGLRINLGQGIS-VEAFVGIPYAKPPIGDL--------RFRKPVP---LEKWDGVYNATTFSPACYQKPWFLEEISFGK----------------FDHFDEDCLYLNVFIPEVSENK-MAVMVWIHGGAYRYGTAEEYEGRFLAAAGVIL-VTVNYRLGPLGWLSTGDEQSRGNYGLWDQHAALMWVKHNIESFGGDANRVTI 224
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Match: tg (thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1]) HSP 1 Score: 83.5741 bits (205), Expect = 1.497e-16 Identity = 53/141 (37.59%), Postives = 73/141 (51.77%), Query Frame = 1
Query: 409 EECLTLNIYVPE-NNHTSPFPVLLFIHG--ESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLS 789
E+CL LNI+VP+ H + VL+F HG SF + D S LA+ G II +T NYRLGL GF+ + D A GN+ D AAL+W+ + F G + VT+ G + LF R I++ G+ LS
Sbjct: 2289 EDCLYLNIFVPKVKPHNAS--VLVFFHGGDNSFGGSAQGPLDPSYLAALGDIIVVTANYRLGLFGFLSTGDEAAAGNWGLLDQQAALRWVRDHAALFGGSAGAVTVAGDRSSADNVGLHLVAPGSRGLFQRAILMGGSVLS 2427
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010324.1 (pep scaffold:Pmarinus_7.0:GL476365:247673:258231:-1 gene:ENSPMAG00000009350.1 transcript:ENSPMAT00000010324.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.0922 bits (170), Expect = 9.068e-13 Identity = 85/366 (23.22%), Postives = 145/366 (39.62%), Query Frame = 1
Query: 748 LFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMN---VSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
LF R + +G LS W+++ Y L + + + + L L+ ++ A E TP +++ GP I +++P + E DV++G+N GF F ++ + + F + F+ Y Y + + + +YTDW D E+R + D ++ PA+ ++H+ S TY Y F + + DA D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +Y ++ Y++ LK +R + + + W EL+P LH FQY
Sbjct: 8 LFQRAVTQSGTALSSWAFNYQPIKYTRMLAEKVTCNRLDTHDLVECLRSRSFHELV-AQEITP-VRYHVAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDVMLGIN-QGEGFKFVEDIVDGEDGVAANDFDYVVSNFVDNLYGYPEGKDELRATIKFMYTDWADRD------NAETRRKTLVALFTDHQWVAPAVATADLHAQYGS------PTYFYAFYHHCQSEMKPAWADAAHGDEIPYVFGVPMVGPTELFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPRDQHYLHIGLKP----RMREHYRATKVAFWLELVPHLHNLHDVFQY 342
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007921.1 (pep scaffold:Pmarinus_7.0:GL476391:291925:322499:1 gene:ENSPMAG00000007162.1 transcript:ENSPMAT00000007921.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 4.213e-12 Identity = 83/370 (22.43%), Postives = 143/370 (38.65%), Query Frame = 1
Query: 748 LFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTP-------KLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPK---LHQSFQY 1764
LF R I +G LS W+ + Y L + +N + L + + L++ F +++ GP I +++P + E DV++G+N G F ++ ++ S F + + F+ Y Y + + + +YTDW + E+R + D ++ PA+ ++H+ S TY+Y F + + DA D+ +FG P N K M LS +M Y +NF K G+PN P P N++ W +Y+ ++ Y++ LK VR + + + W EL+P LH FQY
Sbjct: 9 LFQRAITQSGTALSSWAINYQPVKYTRLLAENVNCN------MLDTQDVVECLRSRSFRELVNQDIKPMRYHVAFGPVIDG-----------DVIPDDPQILMEQGEFLNYDVMLGIN-QGEGLKFVESMVDIDDGVSAANFDNIVSNFVDNLYGYPEGKDELRATIKFMYTDWA------DRNNAETRRKTLVALFTDHQWVAPAMATADLHAQYGS------PTYVYAFYHHCQSEMKPAWADAAHGDETPYVFGVPMVGPTLLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNAPVPQDTKFIHNKPNRYEEMAWSKYSPKDQHYLHIGLKPR----VREHYRATKVAFWLELVPHLHNLHDMFQY 343
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Match: EDO46992 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNV3]) HSP 1 Score: 131.339 bits (329), Expect = 8.171e-32 Identity = 121/485 (24.95%), Postives = 219/485 (45.15%), Query Frame = 1
Query: 406 DEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMG--HGHD---------MKKKLFHRLIIINGN---GLSGWSWSQFSHMYMNALGKYMNVSSKL--LFRQLKREPITNILK--ASEFTPKLKFSSRIGPT--ISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIK-ENYVYNQQS-IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRD-------NSVYDAQFSDDLMMLFGTP------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQS 1755
DE CLTLN+Y P S PVL+FIHG +F S + D S LA+ I+ +T+NYRLG+LGF+ S D + N D AL+W+ NI +F GD ++VT+ G G + + LF + ++G L G + + + + ++V ++ R+ I + ++ + +F P + + P+ I + + T A SR L ++L+V++G D F + L D + ++I+ + ++ Q + + + +YTDW E ++R S+ + +I D + ++P + ++ ++ + +T+ Y F K+ +R + A D LFG N + E ++ +++NFVK G+PN ++ WPQ+T +QYV+ D S++S+ SNL +++ W++ +P L S
Sbjct: 98 DENCLTLNVYKPSATRNSSLPVLVFIHGGAFMRFSAHEDDPSLLATEQGIMVVTINYRLGILGFLCSGD--IKENLGLLDQIYALKWVQNNIERFGGDRSQVTIGGLSAGGESASILMLSPLATGLFTGVFAMSGTPVPTLEGRKDVETAARRVAEVLGCIDVGQRITDCLREKSTAEIVSAMQNVSMKFAPCV--DGHVIPSFWIRHLIGTSALGESREL--------KKLNVMMGATNDEGSFQLHVSPDLSRQDLDHGISRQTFTQYIRNQTWITGQTNQVSHAIEQVYTDWSN-----EDNANKTRESLVD-VITDHWIVVPTV------TTLRACAKAGARTFFYFFEKKPPVERKIKGITQAPGWFRATHGADNSYLFGGDLDMTWVNDSLKADREFAKRFRTFIANFVKTGDPNGA------------TVPTWPQFTPVHQQYVSMD----SQISLGSNLRADKVHFWNKFLPSLTSS 542
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Match: EDO47241 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN07]) HSP 1 Score: 127.487 bits (319), Expect = 6.275e-31 Identity = 141/563 (25.04%), Postives = 237/563 (42.10%), Query Frame = 1
Query: 154 VRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNL-PNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF-PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD-----------MKKKLFHRLIIINGNGLSGWSWSQFSHMYMNA--LGKYMNVSS-KLLFRQLKREPITNILKASEFTPKLKFS--SRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQS---DNQGKTYLYMFSKQI-SYKRDNSVYDAQFSDDLMMLFGTP---NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYP 1767
VR Y GI +A + K V NP E +T F +CPQ + P +F ++ E+CL LN++VP N V+++I+G F G+ Y+ S LA G +I + +NYR+G+ GF+ + N GNY D +LQW+ +NIY+F GD KVT+ G + LF I +G+ W++S ++H A GK + + + + LK + T I++A+ K+K++ + I P I F S ++ L+ K + +++V++G D+ + +D +F +K Y S + + YTDW + + + R M+ M+ DA F PA+ + + + + Q + LY K + S++R A + +LM +FG P N SR +++ +NF K G+PN+P+ WP Y +QY+ SS +R ++ W+ L+P+L S P
Sbjct: 25 VRRYMGIPFAKAERFKAPV------NP-------EPWTTTKNAFNFGKICPQAITPYTANFKTSE-------------------MSEDCLNLNVFVPNNTAAGAMKSVMVWIYGGGFMNGANRLYESSILAGEGDVIVVVVNYRVGIFGFLATGKNGLTGNYGMLDQVKSLQWVKSNIYRFGGDPGKVTIFGESAGGASVGLLMLSPLANGLFRSAIPQSGSAPPMWAFSDYTHAREKASSFGKVIGCADLENMVECLKDKNFTQIVEATN---KIKYTGGAHISPVIDGN-FLPDSPIT--LLREGK--FNDVNVMIGTTDDDGTVMIPEKMPFNISDGMPREF---FLNAVKATY-QTPASPAAVTFQ-YTDWTNITDPYRNRR------MYVDMMTDAMFTAPAVLSASAFLARGCPTYFYEIQYRGPLYFTGKPVPSWQR------AYHASELMFVFGFPLLSNASNPVDANFSRDVIQLWTNFAKTGDPNKPRNASFV----------WPAYDAHYQQYLRLKPSPSSAQHLR----ADRMAFWNVLMPQLIASENQP 516
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Match: EDO47190 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN08]) HSP 1 Score: 121.709 bits (304), Expect = 8.873e-29 Identity = 143/561 (25.49%), Postives = 221/561 (39.39%), Query Frame = 1
Query: 154 VRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPN-MTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF-PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD-----------MKKKLFHRLIIINGNGLSGWSWSQFSHM--YMNALGKYMNVSS-KLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNN---DFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKM-DPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDN----SVYDAQFSDDLMMLFG---TPNHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQS 1755
VR Y GI +A RF PV + F+ K +CPQ+L M F N E+CL L+++VP N V+++I+G +F G+ YD S ++ G +I + +NYR+G+ GF+ + N GNY D +LQW+ NI KF GD+ KVT+ G + LF I +GN W S++S+ +A GK + + + L+ + T IL A++ P + I P I F S ++ L+ K + ++DV++G D+ F + N + S L + ++ I+Y YT+W + DP R S + M+ M+ DA F PA S TYLY F + + D S A ++ LFG N +R +++ +NF K GNPN P WP Y + Y+ SS +R ++ W+ LIP+L S
Sbjct: 48 VRRYMGIPFAK----------AERFKAPVDPTPWTSTRDAFVNGK---MCPQDLTEYMEQFTTND-------------------MSEDCLNLDMFVPNNTAAGAMKSVMVWIYGGAFVSGANRLYDGSVISGEGDVIVVVVNYRVGIFGFLATGKNGVTGNYGMLDQVKSLQWVRGNINKFGGDAGKVTIFGESAGGASVGLLMLSPLANGLFRSAIPQSGNAAGHWVASEYSYAAKVASAFGKASGCTDLDNIVKCLEPKNFTQILDAAKAIPVIG-DGHISPVIDGN-FLPDSPIT--LLKEGK--FNKVDVMIGTTNDDGTVFLPPSSPQRTNADRGAGSANYHSALSLPTANQ---SNETTAAIIYR-YTNWANVNDP--AGNRSVS-LRMYINMMTDAMFTAPAAL------SASGFLAKGCATYLYEFEHRGALGFDGHPIPSWQRAYHGAEIQFLFGMALVSNVTDPVEANFTRDVIQRWTNFAKSGNPNNPDQPSFA----------WPAYDAGSQHYLRLKPSPSSAQHLR----ADHMAFWNVLIPELIAS 543
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Match: EDO35390 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM1]) HSP 1 Score: 115.931 bits (289), Expect = 4.725e-27 Identity = 138/563 (24.51%), Postives = 222/563 (39.43%), Query Frame = 1
Query: 154 VRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN--LPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPEN-NHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMKKKLFHRLIIINGNGL-------SGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKD-------FYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGT---PNHR-----KYSHME--LSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQ 1761
V + GI YA E RF P E+TG + VCPQ LPN +N + E+CL LN+Y P NH PV+++IHG + + N +D S LAS+ +I +T+NYRL LLGF+ +GNY D AL+W+ NI F G+ + VTL G H L ++ GL SG + S F A Y +L +E + N L+ F + + P + +F + + + +P + F + V++G N D F +++ + S F + E + + + + H YT+ DP E+ + ++ D FF P + N S + TY+Y+F+ + ++ ++ +FG+ PN + Y+ +E LS +MK ++F K +PNE WP Y+ ++Y+ DL T VR ++ W++ +PKL Q Q
Sbjct: 49 VEIFLGIPYA------RAPVGELRFADPQPPL---EWTGIRDAKSYRAVCPQAPFLPNFQPLTEN------------------DTISEDCLFLNVYRPTKFNHK--LPVMVWIHGGGYYHATANWFDGSVLASHNNVIVVTINYRLALLGFLHIPGTQLRGNYGMLDQVQALKWVQQNIASFGGNPSHVTLFGESSGAASVTLHILSPLSA-GLFQTAIIESGSAVSPFGAYSPRASNHYDVFIERL--GCFDKENLLNCLREKPFEDFERAVGGVDPRMPGPMFPVPT-VDKVFLPDEPEALLLAGRFNKIESVIIGFNKDEGTFLYSSAEPVTYAPPSIGAFHKAVHEVTLTQNGDDCELLKQAAIHRYTN--HSDPSNPWNLWEN----WKNLMGDTFFFAPVTRTAN------SLAKAGISTYMYLFTHRSTFSMFPPETGVCHFVEVQYVFGSPWKPNPKIGLTSGYTEVERGLSSFLMKLWTDFAKNRDPNETVT--------------WPLYSAERQKYLEIDLVT----RVRRMPHADRVAFWNKFVPKLKQYCQ 548
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Match: EDO31744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX21]) HSP 1 Score: 114.005 bits (284), Expect = 8.468e-27 Identity = 124/451 (27.49%), Postives = 201/451 (44.57%), Query Frame = 1
Query: 286 KFAPVCPQ--NLPNMTDFDKNKDN--YNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMG--------HGH---DMKKKLFHRLIIINGNGLSGWSW-SQFSHMY---MNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQSIY-EILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGT---PNHR-----KYSHME--LSRTMMKYLSNFVK 1548
+++ VCPQ + P +N ++ +S+ HI E+CL LNIY P ++H PV++++HG +GSGN Y S L+S+ II +TLN+RL L GF+ GNY + D AL+W+ NI F GD N VT+ G H H M LFH+ II +GN S +++ S S Y +N LG + R K E +++ F KL F + ++ Q + RNL +++ F +++G D A F +ND + + F+ ++ ++ ++Y I + + H Y + +P +E+ ++ D + P++ + SS TY+Y FS + S+ D+L LFG+ PN R +YS +E LS +M + F K
Sbjct: 27 EYSAVCPQPTHSPRFQPLYENGESSIVDSHCSHIS----------EDCLYLNIYRPAHSHHR-LPVMVWLHGGGNYVGSGNWYHSSVLSSHNDIIVVTLNHRLALFGFLYISGTDLAGNYGYLDQVQALKWVHQNIGNFGGDPNSVTIFGESAGGASVHFHIMSPMSAGLFHKAIIQSGNANSNFAFHSPDSSDYDWIINELGCPDKKNLLRCLRTKKVEEFMKLMRPFSFR-KLGFLLPVT-SVDGQ---FVPDDPRNLQQTHQ-FNNLTSIMIGFTKDEAKFL--------SNDLNPMTFE-LFEKIVQHLHLYGDCEIVKKAVLHRYKN--HTNP------QENMYENIARLFGDMAYFAPSVLTADSFSSAGI------PTYMYQFSHRSSFSNFPEWLGVPHFDELQYLFGSPWQPNPRLDSASRYSLVERGLSSYVMALWTGFAK 437
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Match: nlgn2 (neuroligin 2b [Source:NCBI gene;Acc:100529174]) HSP 1 Score: 190.66 bits (483), Expect = 3.007e-50 Identity = 181/647 (27.98%), Postives = 273/647 (42.19%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK-----------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-------SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLN-GDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIV----PD-DPIVTSTLKMSTSTSPLRTLKLDLSIT 1944
PV + G+ YA+ E RF PP A ++E +FAPVCPQN LP + F N D +Y +++Q E+CL LNIYVP + PV+LFIHG S+ GSGN +D S L++YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LF R I +G+ +S WS + MY L K + S L R+ RE + ++ + + + F + ++ +F D+L+G+N G+ F ++ + S F + F+ Y Y + + E + +YTDW D + R + D ++ PA+ +H ++ Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W +++ +KQY++ LK VR N +N+ W EL+P LH S I N+ RK +V PD DP V+ + S S R +LS+T
Sbjct: 76 PVEQFLGVPYAT------APVGERRFQPPEAPGSWQEIRN---ATQFAPVCPQNVHGVLPEIMLPVWFTDNLDAAATY----------VQNQSEDCLYLNIYVPTEDDVRDRRKKPVMLFIHGGSYMEGSGNMFDGSVLSAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGAACVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSFGDMADLVDCLRRKSFRELVDQDIQPARY--HIAFGP--------VVDGDVVPDDPEILMQQGEFL-NYDILLGVNQGEGLKFVDDSE---GEDGISAASFDYTISNFVDNLYGYPDGKDILRETIKFMYTDWADRD------NSDMRRKTLLALFTDHQWVAPAVATAKLH------AEFQSPVYFYTFHHHCQTEARPDWADAAHGDEIPYVFGIPMVGATDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNLPVPQDTTFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKP----RVRDNYRANKVAFWLELVPHLH-SLHEEIISSITTRLPPNNRRKPSHPGTRSTRHPVVSTYPPDSDPDVSERPRFSPFPSETRDYSTELSVT 671
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Match: nlgn2 (neuroligin 2b [Source:NCBI gene;Acc:100529174]) HSP 1 Score: 191.045 bits (484), Expect = 3.287e-50 Identity = 181/647 (27.98%), Postives = 273/647 (42.19%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQN----LPNM---TDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDMK-----------KKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-------SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLN-GDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIV----PD-DPIVTSTLKMSTSTSPLRTLKLDLSIT 1944
PV + G+ YA+ E RF PP A ++E +FAPVCPQN LP + F N D +Y +++Q E+CL LNIYVP + PV+LFIHG S+ GSGN +D S L++YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LF R I +G+ +S WS + MY L K + S L R+ RE + ++ + + + F + ++ +F D+L+G+N G+ F ++ + S F + F+ Y Y + + E + +YTDW D + R + D ++ PA+ +H ++ Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W +++ +KQY++ LK VR N +N+ W EL+P LH S I N+ RK +V PD DP V+ + S S R +LS+T
Sbjct: 75 PVEQFLGVPYAT------APVGERRFQPPEAPGSWQEIRN---ATQFAPVCPQNVHGVLPEIMLPVWFTDNLDAAATY----------VQNQSEDCLYLNIYVPTEDDVRDRRKKPVMLFIHGGSYMEGSGNMFDGSVLSAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGAACVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSFGDMADLVDCLRRKSFRELVDQDIQPARY--HIAFGP--------VVDGDVVPDDPEILMQQGEFL-NYDILLGVNQGEGLKFVDDSE---GEDGISAASFDYTISNFVDNLYGYPDGKDILRETIKFMYTDWADRD------NSDMRRKTLLALFTDHQWVAPAVATAKLH------AEFQSPVYFYTFHHHCQTEARPDWADAAHGDEIPYVFGIPMVGATDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNLPVPQDTTFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKP----RVRDNYRANKVAFWLELVPHLH-SLHEEIISSITTRLPPNNRRKPSHPGTRSTRHPVVSTYPPDSDPDVSERPRFSPFPSETRDYSTELSVT 670
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Match: ENSORLT00000020295.2 (neuroligin-4, X-linked [Source:NCBI gene;Acc:101168332]) HSP 1 Score: 190.274 bits (482), Expect = 3.649e-50 Identity = 152/536 (28.36%), Postives = 244/536 (45.52%), Query Frame = 1
Query: 286 KFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVP--ENNHT--SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSW----SQFSHMYMNALGKYMNVSSKLL-------FRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRE------LDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVY--NQQSIYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQ 1752
+FAPVCPQ+L + ++ + ++ +L HQ E+CL LNIYVP E+ H PV++++HG S+ G+GN D S LASYG +I ITLNYRLG+LGF+ + D A+GNY D AL+W+ NI F GD ++VT+ G G + LFHR II +G+ L+ W+ S+++ + +G ++ S++L+ +R+L + IT K+ + P I +++P + E DV++G+N G F ++ + + F + +F+ Y Y + ++ E + +YTDW D E+R + D ++ PA+ ++H+ S TY Y F D+ D++ +FG P N K M LS +M Y +NF K G+PN+P P N+F W +YT E+ Y++ LK VR + + + W +L+P LH
Sbjct: 98 QFAPVCPQSLDERSMLVDMMPSWLTA--NLDIAATYLTHQSEDCLYLNIYVPTEEDIHEEGGQRPVMVYVHGGSYTEGTGNMMDGSVLASYGNVIVITLNYRLGVLGFLSTGDQTAKGNYGLLDQIQALRWVKENIAAFGGDPSRVTVFGSGAGASCVSLLTLSHYSEDLFHRAIIQSGSALASWAVNYQPSKYARILGERVGCGIDDSTQLVACLQGRSYRELVEQNIT----------PAKYHTAFAPVIDG-----------DVIPDDPQILMEQGEFLNYDVMLGVN-QGEGVKFVEGIVDSEDGVTAEDFDFAVSDFVDSLYGYPEGRDTLRESIRFMYTDWADRD------NAETRRKTLVALFTDHQWVAPAIATADLHAQYGS------PTYFYSFYHHCQSDATPPWADSAHGDEVPYVFGVPMVGPTDLFNCNFSKNDVM-LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYTPKEQLYLHIGLKP----RVRDHYRATKISFWLQLVPHLHH 592
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Match: nlgn2a (neuroligin 2 [Source:NCBI gene;Acc:100529173]) HSP 1 Score: 189.889 bits (481), Expect = 5.203e-50 Identity = 160/577 (27.73%), Postives = 247/577 (42.81%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTD-------FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-------SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLN-GDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQS--IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV Y G+ YA+ + RF PP A ++E +FAPVCPQN+ + F N D Y +++Q E+CL LNIYVP + PV++FIHG SF G+GN +D S LA+YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LFHR I +G +S WS + Y L + + + L R+ RE + ++ + + + F + ++ +F D+L+G+N G+ F ++ N+ + F + F+ Y Y + + E + +YTDW D + R + D ++ PA+ +H ++ Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W ++ +KQY++ LK VR N +N+ W EL+P LH
Sbjct: 67 PVEQYLGVPYAT------APIGDRRFQPPEAPGSWQEIRN---ATQFAPVCPQNIHGVLPEIMLPVWFTDNLDVAAGY----------IQNQSEDCLYLNIYVPTEDDIRDRRKKPVMMFIHGGSFMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFHRAIAQSGTAISSWSVNYQPLKYTKILARKVGCTYSDTVDLVDCLRRKTFRELVDQDIQPARY--HIAFGP--------VVDGDVVPDDPEILMQQGEFL-NYDILIGVNQGEGLKFVDDS---EDNDGITAAAFDYTISNFVDNLYGYPEGKDILRETIKFMYTDWADRD------NGDMRRKTLLALFTDHQWVAPAIATAKLH------AEFQSPVYFYTFYHHCQTETRPEWADAAHGDEIPYVFGVPMIGATDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKP----RVRDNYRANKVAFWLELVPHLH 593
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Match: nlgn2a (neuroligin 2 [Source:NCBI gene;Acc:100529173]) HSP 1 Score: 189.889 bits (481), Expect = 5.463e-50 Identity = 160/577 (27.73%), Postives = 247/577 (42.81%), Query Frame = 1
Query: 151 PVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTD-------FDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPF---PVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHDM-----------KKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVS-------SKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLN-GDNAGFFFNAPLLLKNNDFSELKFQSKLKEFIKENYVYNQQS--IYEILYHLYTDWQKMDPLFEHEREESRISMFNKMINDAFFIIPALQFCNIHSSTKSQSDNQGKTYLYMFSKQISYKRDNSVYDAQFSDDLMMLFGTP----------NHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXX---XXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLH 1749
PV Y G+ YA+ + RF PP A ++E +FAPVCPQN+ + F N D Y +++Q E+CL LNIYVP + PV++FIHG SF G+GN +D S LA+YG +I +T+NYRLG+LGF+ + D A+GNY D AL+W++ NI F GD ++T+ G G + LFHR I +G +S WS + Y L + + + L R+ RE + ++ + + + F + ++ +F D+L+G+N G+ F ++ N+ + F + F+ Y Y + + E + +YTDW D + R + D ++ PA+ +H ++ Q Y Y F + DA D++ +FG P N K M LS +M Y +NF K G+PN P P N+F W ++ +KQY++ LK VR N +N+ W EL+P LH
Sbjct: 73 PVEQYLGVPYAT------APIGDRRFQPPEAPGSWQEIRN---ATQFAPVCPQNIHGVLPEIMLPVWFTDNLDVAAGY----------IQNQSEDCLYLNIYVPTEDDIRDRRKKPVMMFIHGGSFMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFHRAIAQSGTAISSWSVNYQPLKYTKILARKVGCTYSDTVDLVDCLRRKTFRELVDQDIQPARY--HIAFGP--------VVDGDVVPDDPEILMQQGEFL-NYDILIGVNQGEGLKFVDDSE---DNDGITAAAFDYTISNFVDNLYGYPEGKDILRETIKFMYTDWADRD------NGDMRRKTLLALFTDHQWVAPAIATAKLH------AEFQSPVYFYTFYHHCQTETRPEWADAAHGDEIPYVFGVPMIGATDLFPCNFSKNDVM-LSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKP----RVRDNYRANKVAFWLELVPHLH 599
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Match: SMESG000042617.1 (SMESG000042617.1) HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0 Identity = 378/398 (94.97%), Postives = 381/398 (95.73%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGH---------------DMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLK 1149
MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGF+KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGH DMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNK+FYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQ L+
Sbjct: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFLKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHGAALVHLFSLSKMLKDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKEFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQINLR 398 HSP 2 Score: 66.6254 bits (161), Expect = 3.508e-11 Identity = 31/32 (96.88%), Postives = 32/32 (100.00%), Query Frame = 3
Query: 1185 VNLRNTLSPLHRLAENGSFIRTRKRGVSNFDV 1280
+NLRNTLSPLHRLAENGSFIRTRKRGVSNFDV
Sbjct: 395 INLRNTLSPLHRLAENGSFIRTRKRGVSNFDV 426
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Match: SMESG000042617.1 (SMESG000042617.1) HSP 1 Score: 770 bits (1987), Expect = 0.000e+0 Identity = 378/398 (94.97%), Postives = 381/398 (95.73%), Query Frame = 1
Query: 1 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGH---------------DMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKDFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQSKLK 1149
MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGF+KSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGH DMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNK+FYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQ L+
Sbjct: 4 MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPPVRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENNHTSPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFLKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHGAALVHLFSLSKMLKDMKKKLFHRLIIINGNGLSGWSWSQFSHMYMNALGKYMNVSSKLLFRQLKREPITNILKASEFTPKLKFSSRIGPTISNQLFTYASKLSRNLVPSNKEFYRELDVLVGLNGDNAGFFFNAPLLLKNNDFSELKFQINLR 401 HSP 2 Score: 66.6254 bits (161), Expect = 3.611e-11 Identity = 31/32 (96.88%), Postives = 32/32 (100.00%), Query Frame = 3
Query: 1185 VNLRNTLSPLHRLAENGSFIRTRKRGVSNFDV 1280
+NLRNTLSPLHRLAENGSFIRTRKRGVSNFDV
Sbjct: 398 INLRNTLSPLHRLAENGSFIRTRKRGVSNFDV 429
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Match: SMESG000042619.1 (SMESG000042619.1) HSP 1 Score: 629.017 bits (1621), Expect = 0.000e+0 Identity = 323/324 (99.69%), Postives = 323/324 (99.69%), Query Frame = 1
Query: 1462 MLFGTPNHRKYSHMELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV 2433
MLFGTPNHRKYSHMELSRTMMKYLSNFVKFGNPNEPKPNYPYELYNQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRE FGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV
Sbjct: 1 MLFGTPNHRKYSHMELSRTMMKYLSNFVKFGNPNEPKPNYPYELYNQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKREAFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV 324
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Match: SMESG000042619.1 (SMESG000042619.1) HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0 Identity = 310/311 (99.68%), Postives = 310/311 (99.68%), Query Frame = 1
Query: 1501 MELSRTMMKYLSNFVKFGXXXXXXXXXXXXXXXQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRETFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV 2433
MELSRTMMKYLSNFVKFGNPNEPKPNYPYELYNQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKRE FGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV
Sbjct: 1 MELSRTMMKYLSNFVKFGNPNEPKPNYPYELYNQFSMDYWPQYTVTEKQYVNFDLKTSSKMSVRSNLASNEYRIWDELIPKLHQSFQYPIDWHKREAFGINSNRKTFDNDFDYNMKFIVPDDPIVTSTLKMSTSTSPLRTLKLDLSITKNEEKKIEESVSSTIKEDFIIESIKINTLLWTILAGVAFFLINSIAIMCIYMNIRKLKLLRQNIRGPINNSLSPLRLEFDNEQPVDLNYSGSDLKTPLDFKHETTFLISNQSPDMYATSREISAVRPNCKTLNSCSSIKYPYENTDVKTAYFRICDNDPVTIV 311
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Match: SMESG000077713.1 (SMESG000077713.1) HSP 1 Score: 220.705 bits (561), Expect = 2.096e-66 Identity = 112/216 (51.85%), Postives = 146/216 (67.59%), Query Frame = 1
Query: 154 VRGYFGIRYASLGKIKNTVYTENRFNPPVASFFYEEFTGDFIQDKFAPVCPQNLPNMTDFDKNKDNYNSYWHHIKRILPFLEHQDEECLTLNIYVPENN-HT-SPFPVLLFIHGESFEIGSGNAYDVSKLASYGQIIGITLNYRLGLLGFMKSDDNLAQGNYAFYDIFAALQWISTNIYKFNGDSNKVTLMGHGHD-------MKKKLFHRLIIIN 774
+R Y+GIRYAS+GK+K E RF VASF+YE+F+G + F PVCPQNL N + FD N NSYW H+K I PFL+ Q+EECLTLNIYVP+ N HT + F VL+F+HGE F G+GNAYD+S L+SYG II +T+NYRLG+LGF+ + GN+A YD+FAA+ W+ +I FNGD ++LMG+G K KLF ++N
Sbjct: 2 IRAYYGIRYASVGKLKPGTAPEYRFQQSVASFYYEDFSGTRQLEDFKPVCPQNLVNFSHFDYN--TLNSYWMHVKMIQPFLKDQNEECLTLNIYVPKKNYHTQNQFAVLIFVHGEDFRTGTGNAYDMSVLSSYGDIICVTINYRLGILGFLNMANGDIDGNFALYDLFAAILWVKGHIKHFNGDPENISLMGYGDGAVFIHFFTKSKLFQSKSVLN 215 The following BLAST results are available for this feature:
BLAST of Neuroligin-4, X-linked vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neuroligin-4, X-linked vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neuroligin-4, X-linked vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032503 ID=SMED30032503|Name=Neuroligin-4, X-linked|organism=Schmidtea mediterranea sexual|type=transcript|length=2460bpback to top protein sequence of SMED30032503-orf-1 >SMED30032503-orf-1 ID=SMED30032503-orf-1|Name=SMED30032503-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=812bp MNSSIQISIVFLMKIFISISGKQLKSLNKIDFGDGRFLSGIPINLSSNSPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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