cAMP-regulated phosphoprotein 19

Overview
NamecAMP-regulated phosphoprotein 19
Smed IDSMED30032441
Length (bp)650
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cAMP-regulated phosphoprotein 19 (SMED30032441) t-SNE clustered cells

Violin plots show distribution of expression levels for cAMP-regulated phosphoprotein 19 (SMED30032441) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cAMP-regulated phosphoprotein 19 (SMED30032441) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cAMP-regulated phosphoprotein 19 (SMED30032441) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032441

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30032441h1SMcG0008955 SmedASXL_007631SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
epidermisSMED30032441h1SMcG0008955 dd_Smed_v4_4126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30032441h1SMcG0008955 dd_Smed_v4_4126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30032441h1SMcG0008955 dd_Smed_v4_4126_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967])

HSP 1 Score: 70.8626 bits (172), Expect = 1.216e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967])

HSP 1 Score: 70.8626 bits (172), Expect = 1.216e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967])

HSP 1 Score: 70.8626 bits (172), Expect = 1.216e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967])

HSP 1 Score: 70.8626 bits (172), Expect = 1.216e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:HGNC Symbol;Acc:HGNC:16967])

HSP 1 Score: 70.8626 bits (172), Expect = 1.809e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Match: endos (gene:FBgn0061515 transcript:FBtr0333053)

HSP 1 Score: 70.0922 bits (170), Expect = 2.440e-15
Identity = 44/90 (48.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQ-LAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            E+  +E L+SKYP  +   GG S  LQKRL KG K+FDSGDY +A+   QK   V    K+  +   TTG+ I TPETVPA RK S+  P
Sbjct:   30 EKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAK---QKGGGV----KQVFANKVTTGEAIPTPETVPA-RKTSIIQP 111          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Match: endos (gene:FBgn0061515 transcript:FBtr0075782)

HSP 1 Score: 70.0922 bits (170), Expect = 2.440e-15
Identity = 44/90 (48.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQ-LAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            E+  +E L+SKYP  +   GG S  LQKRL KG K+FDSGDY +A+   QK   V    K+  +   TTG+ I TPETVPA RK S+  P
Sbjct:   30 EKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAK---QKGGGV----KQVFANKVTTGEAIPTPETVPA-RKTSIIQP 111          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Match: endos (gene:FBgn0061515 transcript:FBtr0333052)

HSP 1 Score: 70.0922 bits (170), Expect = 2.440e-15
Identity = 44/90 (48.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQ-LAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            E+  +E L+SKYP  +   GG S  LQKRL KG K+FDSGDY +A+   QK   V    K+  +   TTG+ I TPETVPA RK S+  P
Sbjct:   30 EKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAK---QKGGGV----KQVFANKVTTGEAIPTPETVPA-RKTSIIQP 111          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Match: endos (gene:FBgn0061515 transcript:FBtr0075783)

HSP 1 Score: 70.0922 bits (170), Expect = 2.440e-15
Identity = 44/90 (48.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQ-LAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            E+  +E L+SKYP  +   GG S  LQKRL KG K+FDSGDY +A+   QK   V    K+  +   TTG+ I TPETVPA RK S+  P
Sbjct:   30 EKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAK---QKGGGV----KQVFANKVTTGEAIPTPETVPA-RKTSIIQP 111          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Match: endos (gene:FBgn0061515 transcript:FBtr0304673)

HSP 1 Score: 70.0922 bits (170), Expect = 2.440e-15
Identity = 44/90 (48.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQ-LAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            E+  +E L+SKYP  +   GG S  LQKRL KG K+FDSGDY +A+   QK   V    K+  +   TTG+ I TPETVPA RK S+  P
Sbjct:   30 EKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAK---QKGGGV----KQVFANKVTTGEAIPTPETVPA-RKTSIIQP 111          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Match: arpp19a (cAMP-regulated phosphoprotein 19a [Source:ZFIN;Acc:ZDB-GENE-040426-1281])

HSP 1 Score: 69.3218 bits (168), Expect = 4.589e-15
Identity = 42/86 (48.84%), Postives = 55/86 (63.95%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E+  +  L++KYP L  K G S LL+KRL KG KYFDSGDYN+A+A+ +     LP  + E +  E TGD I TP+ +P  RK SL
Sbjct:   24 EKMEEAKLKAKYPHLGNKPGGSDLLRKRLQKGPKYFDSGDYNMAKAKIKNKQ--LPAAQTEKA--EITGDHIPTPQDLPQ-RKTSL 104          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Match: arpp19a (cAMP-regulated phosphoprotein 19a [Source:ZFIN;Acc:ZDB-GENE-040426-1281])

HSP 1 Score: 69.3218 bits (168), Expect = 4.589e-15
Identity = 42/86 (48.84%), Postives = 55/86 (63.95%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E+  +  L++KYP L  K G S LL+KRL KG KYFDSGDYN+A+A+ +     LP  + E +  E TGD I TP+ +P  RK SL
Sbjct:   24 EKMEEAKLKAKYPHLGNKPGGSDLLRKRLQKGPKYFDSGDYNMAKAKIKNKQ--LPAAQTEKA--EITGDHIPTPQDLPQ-RKTSL 104          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Match: ensaa (endosulfine alpha a [Source:NCBI gene;Acc:569530])

HSP 1 Score: 67.3958 bits (163), Expect = 2.527e-14
Identity = 40/84 (47.62%), Postives = 54/84 (64.29%), Query Frame = 2
Query:   65 LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLA 316
            L++KYP L  K G S  L KRL KG KYFDSGDYN+A+A+  K+ +V+ +  E+ SL   TGD I TP+ +P  +   L + LA
Sbjct:   33 LKAKYPSLGHKPGGSDFLMKRLQKGQKYFDSGDYNMAKAK-MKSKHVVQSAAEK-SL--VTGDHIPTPQDLPQRKNTILTSKLA 112          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Match: ensaa (endosulfine alpha a [Source:NCBI gene;Acc:569530])

HSP 1 Score: 67.0106 bits (162), Expect = 4.411e-14
Identity = 40/84 (47.62%), Postives = 54/84 (64.29%), Query Frame = 2
Query:   65 LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLA 316
            L++KYP L  K G S  L KRL KG KYFDSGDYN+A+A+  K+ +V+ +  E+ SL   TGD I TP+ +P  +   L + LA
Sbjct:   44 LKAKYPSLGHKPGGSDFLMKRLQKGQKYFDSGDYNMAKAK-MKSKHVVQSAAEK-SL--VTGDHIPTPQDLPQRKNTILTSKLA 123          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Match: arpp19b (cAMP-regulated phosphoprotein 19b [Source:ZFIN;Acc:ZDB-GENE-040426-930])

HSP 1 Score: 65.855 bits (159), Expect = 8.579e-14
Identity = 41/88 (46.59%), Postives = 57/88 (64.77%), Query Frame = 2
Query:   47 ETTDEV-LRSKYPQLAKKGGASQLLQKRLCKGH-KYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQ 304
            E  +E+ L+++YP L  + G S LL+KRL KG  KYFDSGDYN+A+A+ +     LP    E +  E TGD I TP+ +P  RK+SL+
Sbjct:   16 EKAEEIKLKARYPHLGARPGGSDLLRKRLQKGQQKYFDSGDYNMAKAKMKN--KQLPAAAAEKT--EITGDHIPTPQDLPQ-RKQSLE 98          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Xenopus
Match: eefsec (eukaryotic elongation factor, selenocysteine-tRNA-specific [Source:Xenbase;Acc:XB-GENE-1010963])

HSP 1 Score: 68.9366 bits (167), Expect = 1.184e-14
Identity = 41/88 (46.59%), Postives = 55/88 (62.50%), Query Frame = 2
Query:   38 TNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            T E+  ++ L++KYP L +K G S  L KRL KG KYFDSGDYN+A+A+ +     LP    + +L   TGD I TP+ +P  RK SL
Sbjct:   28 TPEKAEEQKLKAKYPNLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQ--LPCAGPDKNL--VTGDHIPTPQDLPQ-RKSSL 110          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Match: Arpp19 (cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691])

HSP 1 Score: 69.3218 bits (168), Expect = 3.115e-15
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A  +N++     P +       E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Match: Arpp19 (cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691])

HSP 1 Score: 69.3218 bits (168), Expect = 3.115e-15
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A  +N++     P +       E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Match: Arpp19 (cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691])

HSP 1 Score: 69.3218 bits (168), Expect = 3.115e-15
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A  +N++     P +       E TGD I TP+ +P  RK SL
Sbjct:    4 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 89          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Match: Arpp19 (cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691])

HSP 1 Score: 69.707 bits (169), Expect = 3.443e-15
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A  +N++     P +       E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Match: Arpp19 (cAMP-regulated phosphoprotein 19 [Source:MGI Symbol;Acc:MGI:1891691])

HSP 1 Score: 69.707 bits (169), Expect = 3.443e-15
Identity = 39/93 (41.94%), Postives = 58/93 (62.37%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A  +N++     P +       E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Match: sp|Q712U6|ARP19_PIG (cAMP-regulated phosphoprotein 19 OS=Sus scrofa OX=9823 GN=ARPP19 PE=2 SV=3)

HSP 1 Score: 70.8626 bits (172), Expect = 8.689e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Match: sp|P56211|ARP19_HUMAN (cAMP-regulated phosphoprotein 19 OS=Homo sapiens OX=9606 GN=ARPP19 PE=1 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 8.689e-15
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Match: sp|Q28055|ARP19_BOVIN (cAMP-regulated phosphoprotein 19 OS=Bos taurus OX=9913 GN=ARPP19 PE=1 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 1.130e-14
Identity = 40/91 (43.96%), Postives = 59/91 (64.84%), Query Frame = 2
Query:   29 QMSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++++ E+  +  L+++YP L +K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:   20 KVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKN--KQLPTATPDKT--EVTGDHIPTPQDLPQ-RKPSL 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Match: sp|Q28GU6|ARP19_XENTR (cAMP-regulated phosphoprotein 19 OS=Xenopus tropicalis OX=8364 GN=arpp19 PE=3 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.189e-14
Identity = 41/88 (46.59%), Postives = 56/88 (63.64%), Query Frame = 2
Query:   47 ETTDEV-LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA--QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E ++E+ L+++YP L  K G S  L+KRL KG KYFDSGDYNVA+A  +N++ +   P +       E TGD I TP+ +P  RK SL
Sbjct:   30 EKSEEIKLKARYPNLGPKPGGSDFLRKRLQKGQKYFDSGDYNVAKAKMKNKQLSTAAPDK------TEVTGDHIPTPQDLPQ-RKPSL 110          
BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Match: sp|Q6GQG3|AR19B_XENLA (cAMP-regulated phosphoprotein 19-B OS=Xenopus laevis OX=8355 GN=arpp19-b PE=3 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.392e-14
Identity = 42/89 (47.19%), Postives = 57/89 (64.04%), Query Frame = 2
Query:   38 TNEETTDEV-LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            T+ E  +E+ L+S+YP +  K G S  L+KRL KG KYFDSGDYN+A+A+ +     LPT   + +  E TGD I TP+ +P  RK SL
Sbjct:   27 TSPEKAEEIKLKSRYPNIGPKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQ--LPTAAPDKT--EVTGDHIPTPQDLPQ-RKPSL 110          
BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Match: G4VHV4 (Putative camp-regulated phosphoprotein OS=Schistosoma mansoni OX=6183 GN=Smp_090150.1 PE=3 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 1.386e-27
Identity = 55/93 (59.14%), Postives = 73/93 (78.49%), Query Frame = 2
Query:   35 STNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQN-QKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            S+ EE  +  ++SKYP L K+G  S LLQKRL +GHKYFDSGDYN+ARA+  Q+  +VLP Q EE  L+E+TG+T+ATP++VPAVRKKS+ +P
Sbjct:   13 SSVEEELESKIKSKYPGLNKQGVGSLLLQKRLNRGHKYFDSGDYNMARAKILQQQKHVLPPQTEEAILHESTGETMATPDSVPAVRKKSILSP 105          
BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Match: G4VHV5 (Putative camp-regulated phosphoprotein OS=Schistosoma mansoni OX=6183 GN=Smp_090150.2 PE=3 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 1.396e-27
Identity = 55/93 (59.14%), Postives = 73/93 (78.49%), Query Frame = 2
Query:   35 STNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQN-QKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            S+ EE  +  ++SKYP L K+G  S LLQKRL +GHKYFDSGDYN+ARA+  Q+  +VLP Q EE  L+E+TG+T+ATP++VPAVRKKS+ +P
Sbjct:   14 SSVEEELESKIKSKYPGLNKQGVGSLLLQKRLNRGHKYFDSGDYNMARAKILQQQKHVLPPQTEEAILHESTGETMATPDSVPAVRKKSILSP 106          
BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Match: A0A183R3F1 (Uncharacterized protein OS=Schistosoma rodhaini OX=6188 PE=3 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 2.445e-27
Identity = 55/93 (59.14%), Postives = 73/93 (78.49%), Query Frame = 2
Query:   35 STNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQN-QKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            S+ EE  +  ++SKYP L K+G  S LLQKRL +GHKYFDSGDYN+ARA+  Q+  +VLP Q EE  L+E+TG+T+ATP++VPAVRKKS+ +P
Sbjct:   14 SSVEEELESKIKSKYPGLNKQGVGSLLLQKRLNRGHKYFDSGDYNMARAKILQQQKHVLPPQTEEAILHESTGETMATPDSVPAVRKKSILSP 106          
BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Match: Q86EP6 (Alpha-endosulfine OS=Schistosoma japonicum OX=6182 GN=EWB00_007474 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.042e-26
Identity = 53/90 (58.89%), Postives = 71/90 (78.89%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQN-QKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            EE  +  L++KYP L ++G  S LLQKRL +GHKYFDSGDYN+ARA+  Q+  +VLP Q EE  L+E+TG+T+ATP++VPAVRKKS+ +P
Sbjct:   17 EEEQENKLKTKYPGLNRQGVGSLLLQKRLNRGHKYFDSGDYNMARAKILQQQKHVLPPQTEEAILHESTGETMATPDSVPAVRKKSILSP 106          
BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Match: C1LFB9 (cAMP-regulated phosphoprotein 19 OS=Schistosoma japonicum OX=6182 GN=ARPP-19 PE=2 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 2.623e-26
Identity = 53/90 (58.89%), Postives = 71/90 (78.89%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQN-QKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNP 310
            EE  +  L++KYP L ++G  S LLQKRL +GHKYFDSGDYN+ARA+  Q+  +VLP Q EE  L+E+TG+T+ATP++VPAVRKKS+ +P
Sbjct:   19 EEEQENKLKTKYPGLNRQGVGSLLLQKRLNRGHKYFDSGDYNMARAKILQQQKHVLPPQTEEAILHESTGETMATPDSVPAVRKKSILSP 108          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Match: ensab (endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-060526-294])

HSP 1 Score: 66.6254 bits (161), Expect = 4.309e-14
Identity = 42/90 (46.67%), Postives = 55/90 (61.11%), Query Frame = 2
Query:   35 STNEETTDEV-LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            ++N   T+E  L++KYP L +K G S  L KRL KG KYFDSGDYN+A+A+  K   +      E S+   TGD I TP+ +P  RK SL
Sbjct:   12 NSNPVKTEEAKLKAKYPNLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAK-MKNKQLPAATGPEKSI--VTGDHIPTPQDLPQ-RKSSL 97          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Match: arpp19a (cAMP-regulated phosphoprotein 19-like [Source:NCBI gene;Acc:103032796])

HSP 1 Score: 66.6254 bits (161), Expect = 4.419e-14
Identity = 41/80 (51.25%), Postives = 53/80 (66.25%), Query Frame = 2
Query:   65 LRSKYPQLAKKGGASQLLQKRLCKG-HKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            L++KYP L+ K G S LL+KRL KG  KYFDSGDYN+A+A+ +     LP  + E +  E TGD I TP+ +P  RK SL
Sbjct:   36 LKAKYPHLSGKAGGSDLLRKRLQKGQQKYFDSGDYNMAKAKIKN--KQLPAAQTEKA--EITGDHIPTPQDLPQ-RKPSL 110          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Match: ensab (endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-060526-294])

HSP 1 Score: 66.6254 bits (161), Expect = 4.842e-14
Identity = 40/85 (47.06%), Postives = 52/85 (61.18%), Query Frame = 2
Query:   47 ETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            +T +  L++KYP L +K G S  L KRL KG KYFDSGDYN+A+A+  K   +      E S+   TGD I TP+ +P  RK SL
Sbjct:   23 KTEEAKLKAKYPNLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAK-MKNKQLPAATGPEKSI--VTGDHIPTPQDLPQ-RKSSL 103          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Match: arpp19a (cAMP-regulated phosphoprotein 19-like [Source:NCBI gene;Acc:103032796])

HSP 1 Score: 67.0106 bits (162), Expect = 5.059e-14
Identity = 42/87 (48.28%), Postives = 55/87 (63.22%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKG-HKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E   +  L++KYP L+ K G S LL+KRL KG  KYFDSGDYN+A+A+ +     LP  + E +  E TGD I TP+ +P  RK SL
Sbjct:   36 ERAEEAKLKAKYPHLSGKAGGSDLLRKRLQKGQQKYFDSGDYNMAKAKIKN--KQLPAAQTEKA--EITGDHIPTPQDLPQ-RKPSL 117          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Match: ensab (endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-060526-294])

HSP 1 Score: 66.2402 bits (160), Expect = 5.317e-14
Identity = 40/85 (47.06%), Postives = 52/85 (61.18%), Query Frame = 2
Query:   47 ETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            +T +  L++KYP L +K G S  L KRL KG KYFDSGDYN+A+A+  K   +      E S+   TGD I TP+ +P  RK SL
Sbjct:   20 KTEEAKLKAKYPNLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAK-MKNKQLPAATGPEKSI--VTGDHIPTPQDLPQ-RKSSL 100          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002208.1 (pep scaffold:Pmarinus_7.0:GL491052:3795:4888:-1 gene:ENSPMAG00000002007.1 transcript:ENSPMAT00000002208.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 3.527e-15
Identity = 39/94 (41.49%), Postives = 56/94 (59.57%), Query Frame = 2
Query:   38 TNEETTDEVLRSKYPQLA-KKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLA 316
            + EE  +  LR+KYP +   + G S  L+KRL KG KYFDSGDYN+A+A+ +     LP Q  E+     TGD I TP+ +P  +  ++ + LA
Sbjct:    1 STEEVEEAKLRAKYPNIVPHQPGGSHFLRKRLQKGQKYFDSGDYNMAKAKMKNKQ--LPQQGGEV-----TGDHIPTPQDLPQRKSGAMASKLA 87          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Sea Lamprey
Match: arpp19b (cAMP-regulated phosphoprotein 19b [Source:ZFIN;Acc:ZDB-GENE-040426-930])

HSP 1 Score: 60.4622 bits (145), Expect = 1.901e-12
Identity = 44/97 (45.36%), Postives = 51/97 (52.58%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKG-HKYFDSGDYNVARAQNQK----------AANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E+  +  LR+KYPQL  K G S  L KRL KG  KYFDSGDYN+ +A NQK          A N  P           TGD I TP+ +P  RK SL
Sbjct:    5 EQIEEAKLRAKYPQLGPKTGGSAFLMKRLHKGQQKYFDSGDYNMYKA-NQKNKAVAAAAAAATNSEPACDAGPEKEPVTGDHIPTPQDLPQ-RKPSL 99          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Nematostella
Match: EDO32409 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV53])

HSP 1 Score: 45.8246 bits (107), Expect = 9.417e-7
Identity = 30/86 (34.88%), Postives = 49/86 (56.98%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E + +E  + K+P   KK   + +++KRL KG KYFDSGDY +A+++++      P     L++    G  I TP+ +P  RK S+
Sbjct:   12 ELSEEEKFKRKFPN--KKPMTTDVMRKRLQKGVKYFDSGDYMMAKSRDKNPRG--PVNPAVLAV----GKGIPTPDKIPH-RKTSV 88          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Medaka
Match: ENSA (alpha-endosulfine [Source:NCBI gene;Acc:101165668])

HSP 1 Score: 66.6254 bits (161), Expect = 4.612e-14
Identity = 39/79 (49.37%), Postives = 50/79 (63.29%), Query Frame = 2
Query:   65 LRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            L++KYP L +K G S  L KRL KG KYFDSGDYN+A+A+ +     LP    + +L   TGD I TP+ +P  RK SL
Sbjct:   36 LKAKYPGLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQ--LPVAGPDKNL--VTGDHIPTPQDLPQ-RKSSL 109          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Medaka
Match: ARPP19 (cAMP regulated phosphoprotein 19 [Source:NCBI gene;Acc:101173219])

HSP 1 Score: 60.8474 bits (146), Expect = 6.271e-12
Identity = 38/88 (43.18%), Postives = 53/88 (60.23%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKG-HKYFDSGDYNVARAQ-NQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSL 301
            E++ +  L+++YP L  K G S  L+KRL KG  KYFDSGDYN+A+A+   K     P +K E+     TG  I TP+ +P  RK S+
Sbjct:   25 EKSEEAKLKARYPNLGAKPGGSDFLRKRLQKGGQKYFDSGDYNMAKAKMKNKQLPSAPAEKTEI-----TGGHIPTPQDLPH-RKTSM 106          
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Medaka
Match: ARPP19 (cAMP-regulated phosphoprotein 19 [Source:NCBI gene;Acc:101168529])

HSP 1 Score: 60.4622 bits (145), Expect = 1.004e-11
Identity = 35/79 (44.30%), Postives = 47/79 (59.49%), Query Frame = 2
Query:   44 EETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVP 280
            E+  +  L+++YP L   G    +L+KRL KG KYFDSGDYN+A+A N+     LPT        E TGD I TP+ +P
Sbjct:   30 EKAEEAKLKARYPNL---GHKPDMLRKRLQKGQKYFDSGDYNMAKANNKN--KQLPTAAAP-EKSEITGDHIPTPQDLP 102          
BLAST of cAMP-regulated phosphoprotein 19 vs. Planmine SMEST
Match: SMESG000032735.1 (SMESG000032735.1)

HSP 1 Score: 255.758 bits (652), Expect = 4.871e-88
Identity = 123/124 (99.19%), Postives = 124/124 (100.00%), Query Frame = 2
Query:   32 MSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLATNTTSILCPSVLPVFERDSDREFDSADNN 403
            MSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLATNTTSILCP+VLPVFERDSDREFDSADNN
Sbjct:    1 MSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLATNTTSILCPNVLPVFERDSDREFDSADNN 124          
BLAST of cAMP-regulated phosphoprotein 19 vs. Planmine SMEST
Match: SMESG000071252.1 (SMESG000071252.1)

HSP 1 Score: 56.9954 bits (136), Expect = 3.158e-10
Identity = 46/124 (37.10%), Postives = 57/124 (45.97%), Query Frame = 2
Query:   71 SKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQ--NQKAANVLP---TQKEELS-----------------------------------------LYETTGDTIATPETVPA-VRKKSL 301
            +KYP +A K  AS++LQKRL K  KYFDSGDYNVA+ +   QK    +P   +  E LS                                         L ++TGDTI TP+ VPA VRKKS 
Sbjct:   15 AKYPDIANK--ASKILQKRLNKNVKYFDSGDYNVAKDKVLKQKLQTNMPHSISNNESLSQPGTFDSLDNNLNLPQYRKSLSTSNTDSSINTIEAIGVDEMLKQSTGDTIPTPDNVPAVVRKKSF 136          
BLAST of cAMP-regulated phosphoprotein 19 vs. Planmine SMEST
Match: SMESG000071252.1 (SMESG000071252.1)

HSP 1 Score: 56.9954 bits (136), Expect = 3.468e-10
Identity = 46/124 (37.10%), Postives = 57/124 (45.97%), Query Frame = 2
Query:   71 SKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARAQ--NQKAANVLP---TQKEELS-----------------------------------------LYETTGDTIATPETVPA-VRKKSL 301
            +KYP +A K  AS++LQKRL K  KYFDSGDYNVA+ +   QK    +P   +  E LS                                         L ++TGDTI TP+ VPA VRKKS 
Sbjct:   10 AKYPDIANK--ASKILQKRLNKNVKYFDSGDYNVAKDKVLKQKLQTNMPHSISNNESLSQPGTFDSLDNNLNLPQYRKSLSTSNTDSSINTIEAIGVDEMLKQSTGDTIPTPDNVPAVVRKKSF 131          
The following BLAST results are available for this feature:
BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ARPP191.216e-1543.96cAMP regulated phosphoprotein 19 [Source:HGNC Symb... [more]
ARPP191.216e-1543.96cAMP regulated phosphoprotein 19 [Source:HGNC Symb... [more]
ARPP191.216e-1543.96cAMP regulated phosphoprotein 19 [Source:HGNC Symb... [more]
ARPP191.216e-1543.96cAMP regulated phosphoprotein 19 [Source:HGNC Symb... [more]
ARPP191.809e-1543.96cAMP regulated phosphoprotein 19 [Source:HGNC Symb... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
endos2.440e-1548.89gene:FBgn0061515 transcript:FBtr0333053[more]
endos2.440e-1548.89gene:FBgn0061515 transcript:FBtr0075782[more]
endos2.440e-1548.89gene:FBgn0061515 transcript:FBtr0333052[more]
endos2.440e-1548.89gene:FBgn0061515 transcript:FBtr0075783[more]
endos2.440e-1548.89gene:FBgn0061515 transcript:FBtr0304673[more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
arpp19a4.589e-1548.84cAMP-regulated phosphoprotein 19a [Source:ZFIN;Acc... [more]
arpp19a4.589e-1548.84cAMP-regulated phosphoprotein 19a [Source:ZFIN;Acc... [more]
ensaa2.527e-1447.62endosulfine alpha a [Source:NCBI gene;Acc:569530][more]
ensaa4.411e-1447.62endosulfine alpha a [Source:NCBI gene;Acc:569530][more]
arpp19b8.579e-1446.59cAMP-regulated phosphoprotein 19b [Source:ZFIN;Acc... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
eefsec1.184e-1446.59eukaryotic elongation factor, selenocysteine-tRNA-... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Arpp193.115e-1541.94cAMP-regulated phosphoprotein 19 [Source:MGI Symbo... [more]
Arpp193.115e-1541.94cAMP-regulated phosphoprotein 19 [Source:MGI Symbo... [more]
Arpp193.115e-1541.94cAMP-regulated phosphoprotein 19 [Source:MGI Symbo... [more]
Arpp193.443e-1541.94cAMP-regulated phosphoprotein 19 [Source:MGI Symbo... [more]
Arpp193.443e-1541.94cAMP-regulated phosphoprotein 19 [Source:MGI Symbo... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q712U6|ARP19_PIG8.689e-1543.96cAMP-regulated phosphoprotein 19 OS=Sus scrofa OX=... [more]
sp|P56211|ARP19_HUMAN8.689e-1543.96cAMP-regulated phosphoprotein 19 OS=Homo sapiens O... [more]
sp|Q28055|ARP19_BOVIN1.130e-1443.96cAMP-regulated phosphoprotein 19 OS=Bos taurus OX=... [more]
sp|Q28GU6|ARP19_XENTR1.189e-1446.59cAMP-regulated phosphoprotein 19 OS=Xenopus tropic... [more]
sp|Q6GQG3|AR19B_XENLA1.392e-1447.19cAMP-regulated phosphoprotein 19-B OS=Xenopus laev... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4VHV41.386e-2759.14Putative camp-regulated phosphoprotein OS=Schistos... [more]
G4VHV51.396e-2759.14Putative camp-regulated phosphoprotein OS=Schistos... [more]
A0A183R3F12.445e-2759.14Uncharacterized protein OS=Schistosoma rodhaini OX... [more]
Q86EP62.042e-2658.89Alpha-endosulfine OS=Schistosoma japonicum OX=6182... [more]
C1LFB92.623e-2658.89cAMP-regulated phosphoprotein 19 OS=Schistosoma ja... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ensab4.309e-1446.67endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
arpp19a4.419e-1451.25cAMP-regulated phosphoprotein 19-like [Source:NCBI... [more]
ensab4.842e-1447.06endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
arpp19a5.059e-1448.28cAMP-regulated phosphoprotein 19-like [Source:NCBI... [more]
ensab5.317e-1447.06endosulfine alpha b [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000002208.13.527e-1541.49pep scaffold:Pmarinus_7.0:GL491052:3795:4888:-1 ge... [more]
arpp19b1.901e-1245.36cAMP-regulated phosphoprotein 19b [Source:ZFIN;Acc... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO324099.417e-734.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSA4.612e-1449.37alpha-endosulfine [Source:NCBI gene;Acc:101165668][more]
ARPP196.271e-1243.18cAMP regulated phosphoprotein 19 [Source:NCBI gene... [more]
ARPP191.004e-1144.30cAMP-regulated phosphoprotein 19 [Source:NCBI gene... [more]
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BLAST of cAMP-regulated phosphoprotein 19 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000032735.14.871e-8899.19SMESG000032735.1[more]
SMESG000071252.13.158e-1037.10SMESG000071252.1[more]
SMESG000071252.13.468e-1037.10SMESG000071252.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032441 ID=SMED30032441|Name=cAMP-regulated phosphoprotein 19|organism=Schmidtea mediterranea sexual|type=transcript|length=650bp
TTTTAATTTTCAGTTTTAATAATTCTTACAAATGAGTACAAACGAAGAAA
CAACAGATGAAGTTCTGCGATCGAAATATCCCCAGTTAGCAAAGAAAGGT
GGAGCTAGTCAATTGCTTCAAAAGCGACTTTGCAAAGGGCATAAATATTT
TGATTCTGGAGATTATAACGTTGCTCGAGCTCAGAATCAGAAGGCTGCTA
ATGTTTTGCCAACACAGAAAGAAGAATTGTCACTCTATGAAACAACAGGT
GATACCATAGCGACTCCTGAAACTGTACCTGCAGTGAGGAAAAAAAGCCT
GCAAAATCCACTGGCAACTAATACTACAAGCATTTTGTGTCCCAGTGTGT
TGCCGGTATTTGAACGAGATTCAGATCGAGAATTTGATTCAGCTGATAAC
AACTGAATGAAGATTTAATTGTATAGTAATCAATTGCATTTAGATCTTGC
ATTTCCTTTCGTAATAATTGAGTTTAAATATATTTTGATGTGTTATTGAA
ACCGAGAGTTTCGTAAATTTCACAGATTGTCGGATTGGGATTATGTTTGG
TTGAAATATTGTTTATTATTGGAATTATAACTTGCAAATTGTTGAATTGA
GATTTTTTCAAATTTGAATTTTCGAGACTTCCAGCTGATTATATGAATGC
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protein sequence of SMED30032441-orf-1

>SMED30032441-orf-1 ID=SMED30032441-orf-1|Name=SMED30032441-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=125bp
MSTNEETTDEVLRSKYPQLAKKGGASQLLQKRLCKGHKYFDSGDYNVARA
QNQKAANVLPTQKEELSLYETTGDTIATPETVPAVRKKSLQNPLATNTTS
ILCPSVLPVFERDSDREFDSADNN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0032515negative regulation of phosphoprotein phosphatase activity
GO:0007049cell cycle
GO:0007067mitotic nuclear division
GO:0043086negative regulation of catalytic activity
GO:0051301cell division
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR006760Endosulphine
Vocabulary: molecular function
TermDefinition
GO:0004864protein phosphatase inhibitor activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006760EndosulphinePANTHERPTHR10358ENDOSULFINEcoord: 5..90
NoneNo IPR availablePANTHERPTHR10358:SF21ALPHA-ENDOSULFINEcoord: 5..90