Synaptogyrin

Overview
NameSynaptogyrin
Smed IDSMED30032422
Length (bp)584
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Synaptogyrin (SMED30032422) t-SNE clustered cells

Violin plots show distribution of expression levels for Synaptogyrin (SMED30032422) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032422

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30032422h1SMcG0004298 Contig1892GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30032422h1SMcG0004298 Contig1892GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30032422h1SMcG0004298 dd_Smed_v4_5946_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30032422h1SMcG0004298 dd_Smed_v4_5946_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Synaptogyrin vs. Ensembl Human
Match: SYNGR2 (synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499])

HSP 1 Score: 70.8626 bits (172), Expect = 1.126e-14
Identity = 39/105 (37.14%), Postives = 59/105 (56.19%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRW 372
            VV R + L+++LIV  CI   GY+    S  +  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W
Sbjct:   26 VVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQW 130          
BLAST of Synaptogyrin vs. Ensembl Human
Match: SYNGR2 (synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499])

HSP 1 Score: 70.8626 bits (172), Expect = 1.126e-14
Identity = 39/105 (37.14%), Postives = 59/105 (56.19%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRW 372
            VV R + L+++LIV  CI   GY+    S  +  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W
Sbjct:   26 VVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQW 130          
BLAST of Synaptogyrin vs. Ensembl Human
Match: SYNGR2 (synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499])

HSP 1 Score: 70.4774 bits (171), Expect = 2.898e-14
Identity = 41/114 (35.96%), Postives = 63/114 (55.26%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDI 399
            VV R + L+++LIV  CI   GY+    S  +  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +  N  D+
Sbjct:   26 VVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQW-AVTNPKDV 138          
BLAST of Synaptogyrin vs. Ensembl Human
Match: SYNGR3 (synaptogyrin 3 [Source:HGNC Symbol;Acc:HGNC:11501])

HSP 1 Score: 58.151 bits (139), Expect = 6.351e-10
Identity = 35/103 (33.98%), Postives = 53/103 (51.46%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY-NSDG---LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWN 375
            R  + ++S+ V   I+  GY N+D    L  +F  +  AC FG+AL +   +A   FL+ D   + I           L++ F+ +WSFLW VGFC L N+W 
Sbjct:   29 RVASWVFSIAVFGPIVNEGYVNTDSGPELRCVFNGNAGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVGFCFLTNQWQ 131          
BLAST of Synaptogyrin vs. Ensembl Human
Match: SYNGR3 (synaptogyrin 3 [Source:HGNC Symbol;Acc:HGNC:11501])

HSP 1 Score: 56.9954 bits (136), Expect = 9.068e-10
Identity = 34/97 (35.05%), Postives = 50/97 (51.55%), Query Frame = 1
Query:   97 YSLIVLVCILKAGY-NSDG---LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWN 375
            +S+ V   I+  GY N+D    L  +F  +  AC FG+AL +   +A   FL+ D   + I           L++ F+ +WSFLW VGFC L N+W 
Sbjct:   75 FSIAVFGPIVNEGYVNTDSGPELRCVFNGNAGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVGFCFLTNQWQ 171          
BLAST of Synaptogyrin vs. Ensembl Zebrafish
Match: syngr3b (synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6])

HSP 1 Score: 68.9366 bits (167), Expect = 2.965e-14
Identity = 39/111 (35.14%), Postives = 58/111 (52.25%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L  I+S++V   I+  GY    S+ L  +F  +  ACN+ I + ++  +A  LFL  D     I           LEI F+  W+FLW VGFC L N+W SR ++ ++P
Sbjct:   30 RALAWIFSMVVFASIINEGYVNMGSERLHCVFNKNADACNYAITIGIMAFLASVLFLALDVYFPQISSVKDRKRAVLLEIAFSGFWTFLWFVGFCFLANQW-SRTSDKELP 139          
BLAST of Synaptogyrin vs. Ensembl Zebrafish
Match: syngr3b (synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6])

HSP 1 Score: 69.3218 bits (168), Expect = 3.050e-14
Identity = 39/111 (35.14%), Postives = 58/111 (52.25%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L  I+S++V   I+  GY    S+ L  +F  +  ACN+ I + ++  +A  LFL  D     I           LEI F+  W+FLW VGFC L N+W SR ++ ++P
Sbjct:   30 RALAWIFSMVVFASIINEGYVNMGSERLHCVFNKNADACNYAITIGIMAFLASVLFLALDVYFPQISSVKDRKRAVLLEIAFSGFWTFLWFVGFCFLANQW-SRTSDKELP 139          
BLAST of Synaptogyrin vs. Ensembl Zebrafish
Match: syngr3a (synaptogyrin 3a [Source:ZFIN;Acc:ZDB-GENE-050522-541])

HSP 1 Score: 65.855 bits (159), Expect = 5.674e-13
Identity = 35/111 (31.53%), Postives = 59/111 (53.15%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGYNSDG---LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L+ I+S++V   I+  GY + G   L  +F  + +ACN+G  + ++  +A   F++ D   + I           L+I F+  W+FLW VGFC L N+W  R   +++P
Sbjct:   30 RILSWIFSMVVFGSIINEGYVNHGSQRLYCVFNKNNNACNYGTTIGLIAFLACIFFIILDIKFQQISSIKDRKKAVMLDIGFSGFWAFLWFVGFCFLANQWQ-RTTTDELP 139          
BLAST of Synaptogyrin vs. Ensembl Zebrafish
Match: syngr2b (synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-19])

HSP 1 Score: 58.5362 bits (140), Expect = 1.054e-10
Identity = 31/119 (26.05%), Postives = 61/119 (51.26%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            K    V RFL+ +++++V   I   GY    +   +  +F  ++ AC++G+ + V+  +A   FL+ D     I +  +   +   ++ F+  W+FLW V FCL  ++W+   + + IP
Sbjct:   24 KQPQTVVRFLSWVFAIVVFSSITAEGYVNSTDEAEVRCVFNRNDGACHYGVGIGVIAFLACVGFLLADAILPLISNAQERKYIVMADLAFSGCWTFLWFVCFCLTADQWSKTSDRSGIP 142          
BLAST of Synaptogyrin vs. Ensembl Zebrafish
Match: syngr2b (synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-19])

HSP 1 Score: 58.5362 bits (140), Expect = 1.731e-10
Identity = 31/119 (26.05%), Postives = 61/119 (51.26%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            K    V RFL+ +++++V   I   GY    +   +  +F  ++ AC++G+ + V+  +A   FL+ D     I +  +   +   ++ F+  W+FLW V FCL  ++W+   + + IP
Sbjct:   24 KQPQTVVRFLSWVFAIVVFSSITAEGYVNSTDEAEVRCVFNRNDGACHYGVGIGVIAFLACVGFLLADAILPLISNAQERKYIVMADLAFSGCWTFLWFVCFCLTADQWSKTSDRSGIP 142          
BLAST of Synaptogyrin vs. Ensembl Xenopus
Match: syngr2 (synaptogyrin 2 [Source:NCBI gene;Acc:448480])

HSP 1 Score: 67.0106 bits (162), Expect = 2.560e-13
Identity = 36/115 (31.30%), Postives = 61/115 (53.04%), Query Frame = 1
Query:   40 EIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRW 372
             +E+  K    + R ++ I++LIV  CI+  GY    N   L  IF  +  AC++G+ +  +  +A  LFL  D   +++ +      +   ++ F+ +WSFLW VGFC L N+W
Sbjct:   16 SLENFLKRPETILRIISCIFALIVFACIVSDGYTNIPNESKLTCIFNKNNDACHYGVGIGFLAFLACILFLFLDIYLQTLSNANYRKYIVLADLGFSTLWSFLWFVGFCFLANQW 130          
BLAST of Synaptogyrin vs. Ensembl Xenopus
Match: aif1l (allograft inflammatory factor 1-like [Source:Xenbase;Acc:XB-GENE-953714])

HSP 1 Score: 65.0846 bits (157), Expect = 4.689e-12
Identity = 38/118 (32.20%), Postives = 63/118 (53.39%), Query Frame = 1
Query:   73 VNRFLTLIYSLIVLVCILKAGY-----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDF---TCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            V R ++ ++S++V  CI+  GY      ++  C IF  + SAC +G+ + V+  +   L+L  D       S++D  K  ++S  +I  + +W+F W VGFC L N+W    N ND P
Sbjct:   27 VLRMVSWVFSIVVFGCIINEGYINASTEAEEHC-IFNRNSSACAYGVTVGVLAFLTCLLYLAVDVYFPQISSVKDRKK-TVIS--DIAVSGLWAFFWFVGFCFLANQWQV-SNPNDNP 139          
BLAST of Synaptogyrin vs. Ensembl Xenopus
Match: aif1l (allograft inflammatory factor 1-like [Source:Xenbase;Acc:XB-GENE-953714])

HSP 1 Score: 62.003 bits (149), Expect = 2.534e-11
Identity = 51/150 (34.00%), Postives = 82/150 (54.67%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY-----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDF---TCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRI 504
            R ++ ++S++V  CI+  GY      ++  C IF  + SAC +G+ + V+  +   L+L  D       S++D  K  I    +I  + +W+F W VGFC L N+W     N++       + +AAI+FSFFSIFTW  Q + A +RYR+
Sbjct:   29 RMVSWVFSIVVFGCIINEGYINASTEAEEHC-IFNRNSSACAYGVTVGVLAFLTCLLYLAVDVYFPQISSVKDRKKTVIS---DIAVSGLWAFFWFVGFCFLANQWQVSNPNDNPMNEGADAARAAIAFSFFSIFTWAGQAVLAYQRYRL 174          
BLAST of Synaptogyrin vs. Ensembl Xenopus
Match: aif1l (allograft inflammatory factor 1-like [Source:Xenbase;Acc:XB-GENE-953714])

HSP 1 Score: 58.9214 bits (141), Expect = 1.546e-10
Identity = 34/113 (30.09%), Postives = 55/113 (48.67%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY-----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R ++ ++S++V  CI+  GY      ++  C IF  + SAC +G+ + V+  +   L+L  D     I            +I  + +W+F W VGFC L N+W    N ND P
Sbjct:   29 RMVSWVFSIVVFGCIINEGYINASTEAEEHC-IFNRNSSACAYGVTVGVLAFLTCLLYLAVDVYFPQISSVKDRKKTVISDIAVSGLWAFFWFVGFCFLANQWQV-SNPNDNP 139          
BLAST of Synaptogyrin vs. Ensembl Xenopus
Match: SYNGR3 (synaptogyrin 3 [Source:NCBI gene;Acc:100489723])

HSP 1 Score: 58.5362 bits (140), Expect = 4.064e-10
Identity = 47/152 (30.92%), Postives = 78/152 (51.32%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRI 504
            K    + R ++ ++S++V   ++  G    +S  L  ++  ++ ACN+ I + VV   A   F V D     I           ++I F+ IWSFLW V FC L ++W  R  + D+P     + +A I FSFFS+F+W    + A++RYR+
Sbjct:   22 KQPQTILRIISWVFSIVVFGSLVNEGSINVDSPELYCVYNQNDDACNYAITIGVVAFFASICFFVVDIYFPQISSVKDRKKAVMIDIGFSAIWSFLWFVSFCFLADQW--RKTSYDVP-QGADAARAGIVFSFFSVFSWCASAVKAMQRYRL 170          
BLAST of Synaptogyrin vs. Ensembl Mouse
Match: Syngr2 (synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324])

HSP 1 Score: 73.1738 bits (178), Expect = 5.433e-16
Identity = 40/112 (35.71%), Postives = 61/112 (54.46%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            VV R ++++ +LIV  CI   GY     SD L  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +    +
Sbjct:   26 VVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQD 137          
BLAST of Synaptogyrin vs. Ensembl Mouse
Match: Syngr2 (synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324])

HSP 1 Score: 73.9442 bits (180), Expect = 7.100e-16
Identity = 40/112 (35.71%), Postives = 61/112 (54.46%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            VV R ++++ +LIV  CI   GY     SD L  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +    +
Sbjct:   26 VVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQD 137          
BLAST of Synaptogyrin vs. Ensembl Mouse
Match: Syngr2 (synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324])

HSP 1 Score: 67.3958 bits (163), Expect = 1.948e-14
Identity = 39/111 (35.14%), Postives = 59/111 (53.15%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNS 378
            ++ L +   L  + +LIV  CI   GY     SD L  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +
Sbjct:    5 RLPLPMASPLPQVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAA 115          
BLAST of Synaptogyrin vs. Ensembl Mouse
Match: Syngr3 (synaptogyrin 3 [Source:MGI Symbol;Acc:MGI:1341881])

HSP 1 Score: 59.6918 bits (143), Expect = 1.295e-10
Identity = 36/103 (34.95%), Postives = 53/103 (51.46%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY-NSDG---LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWN 375
            R ++ ++S+ V   I+  GY NSD    L  +F  +  AC FG+ L +   IA   FL+ D   + I           L++ F+ +WSFLW VGFC L N+W 
Sbjct:   29 RVVSWVFSIAVFGPIVNEGYVNSDSGPELRCVFNGNAGACRFGVVLGLGAFIACVAFLLLDVRFQQISSVRDRRRAVLLDLGFSGVWSFLWFVGFCFLTNQWQ 131          
BLAST of Synaptogyrin vs. Ensembl Mouse
Match: Syngr2 (synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324])

HSP 1 Score: 54.6842 bits (130), Expect = 4.404e-9
Identity = 26/74 (35.14%), Postives = 41/74 (55.41%), Query Frame = 1
Query:  172 DESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +    +
Sbjct:   34 NEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQD 107          
BLAST of Synaptogyrin vs. UniProt/SwissProt
Match: sp|O54980|SNG2_RAT (Synaptogyrin-2 OS=Rattus norvegicus OX=10116 GN=Syngr2 PE=1 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 2.130e-15
Identity = 40/112 (35.71%), Postives = 63/112 (56.25%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            VV R ++++ +LIV  CI   GY    +SD L  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +   ++
Sbjct:   26 VVTRLVSMVLALIVFSCIFGEGYINLHSSDQLHCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPDD 137          
BLAST of Synaptogyrin vs. UniProt/SwissProt
Match: sp|O55101|SNG2_MOUSE (Synaptogyrin-2 OS=Mus musculus OX=10090 GN=Syngr2 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 4.966e-15
Identity = 40/112 (35.71%), Postives = 61/112 (54.46%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            VV R ++++ +LIV  CI   GY     SD L  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W +    +
Sbjct:   26 VVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQD 137          
BLAST of Synaptogyrin vs. UniProt/SwissProt
Match: sp|A7E3W5|SNG2_BOVIN (Synaptogyrin-2 OS=Bos taurus OX=9913 GN=SYNGR2 PE=2 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.406e-14
Identity = 40/116 (34.48%), Postives = 61/116 (52.59%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            K   VV R + L+++LIV  CI   GY    +S     +F  +E AC +G A+ V+  +A   F V D     I + T    L   +++F+ +W+FLW VGFC L N+W +   N+
Sbjct:   22 KQPQVVVRAVCLVFALIVFSCIFGEGYSNTHDSQQQYCVFNRNEDACRYGSAIGVLAFLASAFFFVVDIYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKKND 137          
BLAST of Synaptogyrin vs. UniProt/SwissProt
Match: sp|O43760|SNG2_HUMAN (Synaptogyrin-2 OS=Homo sapiens OX=9606 GN=SYNGR2 PE=1 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 5.406e-14
Identity = 39/105 (37.14%), Postives = 59/105 (56.19%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRW 372
            VV R + L+++LIV  CI   GY+    S  +  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W
Sbjct:   26 VVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQW 130          
BLAST of Synaptogyrin vs. UniProt/SwissProt
Match: sp|A8MWL6|SNG2L_HUMAN (Putative synaptogyrin-2 like protein OS=Homo sapiens OX=9606 PE=5 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.169e-13
Identity = 40/105 (38.10%), Postives = 59/105 (56.19%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRW 372
            VV R L L+++LIV  CI   GY+    S  +  +F  +E AC +G A+ V+  +A   FLV D     I + T    L   +++F+ +W+FLW VGFC L N+W
Sbjct:   26 VVARALCLVFALIVFSCIYGEGYSNTHKSKQMYCVFNHNEDACRYGSAIGVLAFLAS-AFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQW 129          
BLAST of Synaptogyrin vs. TrEMBL
Match: U3F671 (Synaptogyrin OS=Micrurus fulvius OX=8637 PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.666e-14
Identity = 57/155 (36.77%), Postives = 89/155 (57.42%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFE 522
            V+ R  + +++LIV  CI+  GY+    S  L  IF   E AC +GI + VV  +A   F + D     I   T    L   ++ F+ +W+FLW +GFC+L N+W+S    + I G    S +A+I+FSFFSIF+W     +A++RYR+ V++F+
Sbjct:   28 VIARIFSAVFALIVFSCIIGEGYSNQKSSPQLYCIFNHSEDACRYGIGIGVVAFLACVFFFMVDIYFPQISSATDRKYLVIADLAFSAVWTFLWFIGFCVLTNQWSSVQPGDVIIG--ADSARASIAFSFFSIFSWGLLIAFALQRYRMGVQDFD 180          
BLAST of Synaptogyrin vs. TrEMBL
Match: G1KT11 (Synaptogyrin 2 OS=Anolis carolinensis OX=28377 GN=SYNGR2 PE=4 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 3.041e-14
Identity = 58/155 (37.42%), Postives = 93/155 (60.00%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGY---NSDG-LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFE 522
            V+ R L+ +++LIV  CI+  GY   +S+G L  IF  +E AC +GI + VV  +A   F + D     I + T    L   ++ F+ +W+FLW +GFC+L N+W S  + +   G    S +A+I+FSFFSIF+W     +A++RYR+ V++F+
Sbjct:   37 VLARLLSALFALIVFSCIIGEGYTNIHSEGELHCIFNHNEHACRYGIGIGVVAFLACVFFFMVDIYFPQISNVTDRKYLVMADLGFSALWTFLWFIGFCVLTNQWASTLSTDVFIG--ADSARASIAFSFFSIFSWGLLITFALQRYRMGVQDFD 189          
BLAST of Synaptogyrin vs. TrEMBL
Match: V8P8P6 (Synaptogyrin OS=Ophiophagus hannah OX=8665 GN=SYNGR2 PE=3 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 3.306e-14
Identity = 56/155 (36.13%), Postives = 89/155 (57.42%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFE 522
            V+ R  + +++LIV  CI+  GY    +S  L  IF   E AC +GI + VV  +A   F + D     I   T    L   ++ F+ +W+FLW +GFC+L N+W+S    + + G    S +A+I+FSFFSIF+W     +A++RYR+ V++F+
Sbjct:   28 VIARIFSAVFALIVFSCIIGEGYTNHNSSSQLYCIFNHSEDACRYGIGIGVVAFLASVFFFMVDIYFPQISSATDRKYLVMADLAFSAVWTFLWFIGFCVLTNQWSSVQPGDVLIG--ADSARASIAFSFFSIFSWGLLIAFALQRYRMGVQDFD 180          
BLAST of Synaptogyrin vs. TrEMBL
Match: A0A2D4JAC2 (MARVEL domain-containing protein (Fragment) OS=Micrurus lemniscatus lemniscatus OX=129467 PE=4 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.465e-14
Identity = 57/155 (36.77%), Postives = 89/155 (57.42%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYN----SDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFE 522
            V+ R  + +++LIV  CI+  GY+    S  L  IF   E AC +GI + VV  +A   F + D     I   T    L   ++ F+ +W+FLW +GFC+L N+W+S    + I G    S +A+I+FSFFSIF+W     +A++RYR+ V++F+
Sbjct:   60 VIARIFSAVFALIVFSCIIGEGYSNPKWSPELQCIFNHSEDACRYGIGIGVVAFLACVFFFMVDIYFPQISSATDRKYLVIADLAFSAVWTFLWFIGFCVLTNQWSSVQPGDVIIG--ADSARASIAFSFFSIFSWGLLIAFALQRYRMGVQDFD 212          
BLAST of Synaptogyrin vs. TrEMBL
Match: A0A0B8RQ11 (Synaptogyrin OS=Boiga irregularis OX=92519 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.221e-13
Identity = 55/155 (35.48%), Postives = 87/155 (56.13%), Query Frame = 1
Query:   70 VVNRFLTLIYSLIVLVCILKAGYNSDGLCS----IFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFE 522
            V+ R  + +++LIV  CI+  GY S    S    IF   E AC +GI + VV  +A   F + D     I   T    L   ++ F+ +W+FLW +GFC+L N+W+S   ++   G    S +A+I+FSFFS F+W     +A++RYR+ V++F+
Sbjct:   28 VIARIFSAVFALIVFSCIIGEGYTSKTESSELYCIFNRSEDACRYGIGIGVVAFLACIFFFMVDIYFPQISSATDRKYLVMADLAFSAVWTFLWFIGFCVLTNQWSSTQLSDVSIG--ADSARASIAFSFFSTFSWGLLIAFALQRYRMGVQDFD 180          
BLAST of Synaptogyrin vs. Ensembl Cavefish
Match: syngr3a (synaptogyrin 3 [Source:NCBI gene;Acc:103035002])

HSP 1 Score: 67.0106 bits (162), Expect = 1.678e-13
Identity = 37/111 (33.33%), Postives = 59/111 (53.15%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L+ I+S++V   I+  GY   +S+ L  +F  +  ACN+GI + +V  IA   F++ D   + I           LEI F+  W+F+W V FC L N+W  R   +++P
Sbjct:   30 RILSWIFSMVVFGSIINEGYVNFDSETLYCVFNKNYDACNYGITIGLVAFIACIFFMILDMKFQQISSVKDRKKAVMLEIGFSGFWTFMWFVCFCFLANQWQ-RTTTDELP 139          
BLAST of Synaptogyrin vs. Ensembl Cavefish
Match: syngr3a (synaptogyrin 3 [Source:NCBI gene;Acc:103035002])

HSP 1 Score: 67.0106 bits (162), Expect = 1.799e-13
Identity = 37/111 (33.33%), Postives = 59/111 (53.15%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L+ I+S++V   I+  GY   +S+ L  +F  +  ACN+GI + +V  IA   F++ D   + I           LEI F+  W+F+W V FC L N+W  R   +++P
Sbjct:   30 RILSWIFSMVVFGSIINEGYVNFDSETLYCVFNKNYDACNYGITIGLVAFIACIFFMILDMKFQQISSVKDRKKAVMLEIGFSGFWTFMWFVCFCFLANQWQ-RTTTDELP 139          
BLAST of Synaptogyrin vs. Ensembl Cavefish
Match: syngr2b (synaptogyrin-2 [Source:NCBI gene;Acc:103034452])

HSP 1 Score: 65.855 bits (159), Expect = 5.086e-13
Identity = 32/112 (28.57%), Postives = 62/112 (55.36%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L+ ++S++V   I   GY    N   +  +F  ++ AC++G+ + ++G +A   FL+ D     + +  +   + T +++F+  W+FLW V FC+L N+W +  + N IP
Sbjct:   32 RVLSWVFSIVVFATITAEGYVNPPNHSQVVCVFNKNDGACHYGVGIGIIGFLACVGFLMVDIYLPMMSNAQERKRVVTADLVFSAAWTFLWFVCFCVLANQWANTVDVNGIP 143          
BLAST of Synaptogyrin vs. Ensembl Cavefish
Match: syngr2b (synaptogyrin-2 [Source:NCBI gene;Acc:103034452])

HSP 1 Score: 65.4698 bits (158), Expect = 8.611e-13
Identity = 32/112 (28.57%), Postives = 62/112 (55.36%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            R L+ ++S++V   I   GY    N   +  +F  ++ AC++G+ + ++G +A   FL+ D     + +  +   + T +++F+  W+FLW V FC+L N+W +  + N IP
Sbjct:   32 RVLSWVFSIVVFATITAEGYVNPPNHSQVVCVFNKNDGACHYGVGIGIIGFLACVGFLMVDIYLPMMSNAQERKRVVTADLVFSAAWTFLWFVCFCVLANQWANTVDVNGIP 143          
BLAST of Synaptogyrin vs. Ensembl Cavefish
Match: syngr3b (synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6])

HSP 1 Score: 60.4622 bits (145), Expect = 8.412e-11
Identity = 38/118 (32.20%), Postives = 58/118 (49.15%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            K    V R L  I+S++V   I+  GY    S+ L  ++  +  ACN+ I + +V  +A   FL  D     I        +   E+ F+  W+FLW VGFC L N+W SR +  ++P
Sbjct:   95 KRPQTVLRLLAWIFSMVVFGSIINEGYVNMGSERLHCVYNKNADACNYAITIGLVAFLACLFFLGLDIYFPQISSVKDRKRVVLFEMGFSGFWTFLWFVGFCFLANQW-SRTSLEELP 211          
BLAST of Synaptogyrin vs. Ensembl Sea Lamprey
Match: syngr2b (synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-19])

HSP 1 Score: 68.9366 bits (167), Expect = 6.981e-15
Identity = 43/122 (35.25%), Postives = 68/122 (55.74%), Query Frame = 1
Query:   58 KIMLVVNRFLTL-IYSLIVLVCILKAGYNSDGLCS-----IFLFDESACNFGIALPVVGIIALFLFLVFDFTCESI-RDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWN--SRGNNND 396
            K  L + R L+  +++++VL CI   GY + G        IF  +  AC +G+A+ V+  +A  L LV D    SI     + NIL  +E++F+++W+F+W VGFC L N+W+  S   N D
Sbjct:   25 KKPLTILRLLSWWLFAVVVLACITNEGYANFGQKEPSIQCIFNLNGDACRYGVAIGVIAFLAATLLLVLDLYVPSIVGPLDRKNILR-VEVVFSVLWTFMWFVGFCFLTNQWSKTSEQKNGD 145          
BLAST of Synaptogyrin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006063.1 (pep scaffold:Pmarinus_7.0:GL476493:599143:603638:1 gene:ENSPMAG00000005478.1 transcript:ENSPMAT00000006063.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 5.085e-12
Identity = 49/145 (33.79%), Postives = 72/145 (49.66%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY-NSDG--LCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRI 504
             F+   +S++V  CI+  GY N+ G  L  IF  +  AC +GI + VV   A   FL  D     I            ++ F+  W+F+W VGFCLL N+W    ++    G    S +A I+F FFSI +W      A+RR+R+
Sbjct:    2 HFVLQFFSIVVFGCIVNEGYTNNQGSKLHCIFNGNGDACRYGITIGVVAFFACVAFLALDAYFPQISSVKDRKRAVLADLAFSAFWAFMWFVGFCLLTNQWRETPDSKVPNGIGADSARATIAFCFFSIISWSGIAFLALRRFRL 146          
BLAST of Synaptogyrin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004662.1 (pep scaffold:Pmarinus_7.0:GL501065:8790:19293:1 gene:ENSPMAG00000004245.1 transcript:ENSPMAT00000004662.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 6.111e-10
Identity = 55/162 (33.95%), Postives = 83/162 (51.23%), Query Frame = 1
Query:   43 IEDKYKIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRN 516
            ++    IM VVN     ++S+IV  CI   GY    +S  L  +F  + +AC FGIA+  +  +A    L+ D     I        +   ++ F+  WSFLW V FC L N+W  + + +  P +   S +AAI+FSFFSI +W    I  IRRY++ V +
Sbjct:   21 MKQPQTIMRVVN----WVFSVIVFGCISNEGYVSTNSSPDLYCVFNRNGNACRFGIAIGAIAFLASSALLLLDLYFPQISSVKDRRKVVIFDMAFSAAWSFLWFVCFCFLTNQWQ-KTSADVAPSYSHDSARAAITFSFFSIISWYCSSIKCIRRYKLGVDS 177          
BLAST of Synaptogyrin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003034.1 (pep scaffold:Pmarinus_7.0:GL485592:66:4677:1 gene:ENSPMAG00000002768.1 transcript:ENSPMAT00000003034.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 3.380e-8
Identity = 49/155 (31.61%), Postives = 79/155 (50.97%), Query Frame = 1
Query:   88 TLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFD--FTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN--DIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFEAY 528
            + +++++V  CI+  G+     S  L  ++  +E AC    A  ++  ++   FLV D  FT  S     K  +L   E+  + +W+FLW V FC L N+W+     +  DI G      +AAI+FSFFSI TW+   I+  ++YR+     E Y
Sbjct:   34 STVFAIVVFGCIVGEGHINHSQSSTLHCVYNDNEHACGLATATAILSAVSALAFLVLDVRFTDISSVQHRKAAVLG--ELGLSGLWAFLWFVCFCFLTNQWSKTAFASWMDIVGGS---ARAAIAFSFFSIPTWVGLTIFIFQKYRLGAHFGEEY 183          
BLAST of Synaptogyrin vs. Ensembl Medaka
Match: ENSORLT00000016399.2 (synaptogyrin 3 [Source:NCBI gene;Acc:101166799])

HSP 1 Score: 70.8626 bits (172), Expect = 8.005e-15
Identity = 41/118 (34.75%), Postives = 62/118 (52.54%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            K    + R L+ I+SL+V   I+  GY    S+ L  +F  +  ACN+G+ + +VG++A   F + D+   SI           LEI F+  W+FL+ V FC L N+W SR    D+P
Sbjct:   23 KQPQTILRVLSWIFSLVVFASIVNEGYYNMGSERLHCVFNKNADACNYGVFVGLVGLLACSFFFMLDYKFSSISSIKDRKKAVMLEIGFSGFWTFLYFVSFCFLANQW-SRTKKEDLP 139          
BLAST of Synaptogyrin vs. Ensembl Medaka
Match: SYNGR3 (synaptogyrin-3 [Source:NCBI gene;Acc:101164956])

HSP 1 Score: 66.2402 bits (160), Expect = 3.679e-13
Identity = 37/108 (34.26%), Postives = 58/108 (53.70%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY---NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNN 393
            R L+ ++S++V  CI+  GY    S+ L  +F  +  ACN+G+ L V   +    FLV DF   S+ +         L++IF+ + SFLW VGFC L N+W +   + 
Sbjct:   31 RLLSWVFSIVVFSCIVNEGYINIGSERLLCVFNNNADACNYGLTLGVGCFLGSLCFLVLDFYFPSMSNIKDRKRAVLLDLIFSGLASFLWFVGFCFLANQWQATSPDQ 138          
BLAST of Synaptogyrin vs. Ensembl Medaka
Match: ENSORLT00000009770.2 (synaptogyrin-2 [Source:NCBI gene;Acc:101171415])

HSP 1 Score: 58.151 bits (139), Expect = 2.493e-10
Identity = 47/164 (28.66%), Postives = 81/164 (49.39%), Query Frame = 1
Query:   40 EIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNF 519
            ++E   K    + RFL+ I+S++V   I   GY      +    +F  ++ AC++ + + V+  +A  LFL+ D     + +  +   +   +++F+ +W+ LW + FC L N+W               + +AAISFSFFS  TW   F +A  RYR  V +F
Sbjct:   16 DLESFVKKPQTILRFLSWIFSIVVFATITAEGYVNPMTEENTKCMFNGNDGACSYAVGIGVISFLACVLFLILDAYFPKLSNANERKYIVVADLVFSGVWTILWFICFCYLANQWGKTTAGTAA----PDAARAAISFSFFSTATWGLLFYFAFGRYRQGVDDF 175          
BLAST of Synaptogyrin vs. Ensembl Medaka
Match: syngr2b (synaptogyrin-2 [Source:NCBI gene;Acc:101157351])

HSP 1 Score: 56.6102 bits (135), Expect = 1.153e-9
Identity = 33/119 (27.73%), Postives = 61/119 (51.26%), Query Frame = 1
Query:   58 KIMLVVNRFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIP 402
            +  L V R L+ +++++V  CI   GY     S  +  IF  ++SAC++ + + V+  +A   FL+ D          +  +    ++ F+ +W+FLW V FCLL ++W+   +   IP
Sbjct:   26 RQPLTVVRVLSWVFAIVVFSCIESEGYINAPTSPQVKCIFNKNDSACHYAVGIGVIAFLACVGFLLLDVYLLFSSSAQERKLAVAADLGFSGLWTFLWFVCFCLLTSQWSRTEDMRGIP 144          
BLAST of Synaptogyrin vs. Ensembl Medaka
Match: syngr1b (synaptogyrin 1 [Source:NCBI gene;Acc:101173609])

HSP 1 Score: 55.8398 bits (133), Expect = 1.879e-9
Identity = 45/146 (30.82%), Postives = 72/146 (49.32%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGY----NSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRI 504
            R ++ ++S+++  CI   GY    N      IF  +++ACN+G+ +  +  +    FL  D     I            +I  +  WSF+W VGFC L N+W      ++       + +AAI+FSFFSIFTW  Q   A +RY++
Sbjct:   31 RIVSWLFSIVIFGCIANEGYINRQNEMEQYCIFNRNQNACNYGVFMGSMAFLCCIAFLALDIYFPQISSVKDRKKAVLADIGVSAFWSFMWFVGFCFLANQWQVSKEEDNPLREGGDAARAAITFSFFSIFTWAAQSFLAFQRYKL 176          
BLAST of Synaptogyrin vs. Planmine SMEST
Match: SMESG000031799.1 (SMESG000031799.1)

HSP 1 Score: 297.36 bits (760), Expect = 2.455e-104
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 1
Query:   37 MEIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRNFEAYDQL 537
            MEIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRISSIQAAISFSFFSIFTWIYQFIWAIRRYRIRVRNFEAYDQL
Sbjct:    1 MEIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNSRGNNNDIPGWRISSIQAAISFSFFSIFTWIYQFIWAIRRYRIRVRNFEAYDQL 167          
BLAST of Synaptogyrin vs. Planmine SMEST
Match: SMESG000051237.1 (SMESG000051237.1)

HSP 1 Score: 68.5514 bits (166), Expect = 2.933e-14
Identity = 57/172 (33.14%), Postives = 92/172 (53.49%), Query Frame = 1
Query:   40 EIEDKYKIMLVVNRFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNR-WNSRGNNNDIPGWRXXXXXXXXXXXXXXXXTWIYQFIWAIRRYRIRVRN-FEAYDQL*FQQ 549
            + ++  K   V+ R ++L++S+IV  CI    Y  D  C+ +  D +ACN+G  + V+  IA   FL+ D     + +         ++++F+ IW FLW VGFC L NR  N++     +   R     AAI+FSFFSI +W  Q  +A+R+Y+  V + F + D +  QQ
Sbjct:   15 DFQEYIKSPNVILRIISLVFSIIVFGCIANGVYYKD-KCA-YNNDMNACNYGTVIGVIACIACLAFLIGDAMFHQLSNVDHRKYYVVVDVLFSGIWCFLWFVGFCYLTNRLSNTKTEEGSVSNAR-----AAIAFSFFSIISWALQCYFAVRKYQSGVGDLFASSDDVLDQQ 179          
BLAST of Synaptogyrin vs. Planmine SMEST
Match: SMESG000063084.1 (SMESG000063084.1)

HSP 1 Score: 57.3806 bits (137), Expect = 5.108e-10
Identity = 28/100 (28.00%), Postives = 57/100 (57.00%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNS 378
            R ++L++S+IV  CI   G  ++ +C ++  D SAC+F   + V+  +    F++ D   +++ +  +   +   ++ F+ +W+F W V FC L NRW++
Sbjct:   24 RIVSLLFSIIVFGCISSGG-RANKVC-LYNKDNSACSFATGIGVIAFLGAICFIISDVIFDNVSNIKRRKHIILGDVGFSGLWTFFWFVSFCYLTNRWSN 121          
BLAST of Synaptogyrin vs. Planmine SMEST
Match: SMESG000063084.1 (SMESG000063084.1)

HSP 1 Score: 56.9954 bits (136), Expect = 6.233e-10
Identity = 28/100 (28.00%), Postives = 57/100 (57.00%), Query Frame = 1
Query:   79 RFLTLIYSLIVLVCILKAGYNSDGLCSIFLFDESACNFGIALPVVGIIALFLFLVFDFTCESIRDFTKLNILSTLEIIFTLIWSFLWLVGFCLLVNRWNS 378
            R ++L++S+IV  CI   G  ++ +C ++  D SAC+F   + V+  +    F++ D   +++ +  +   +   ++ F+ +W+F W V FC L NRW++
Sbjct:   30 RIVSLLFSIIVFGCISSGG-RANKVC-LYNKDNSACSFATGIGVIAFLGAICFIISDVIFDNVSNIKRRKHIILGDVGFSGLWTFFWFVSFCYLTNRWSN 127          
The following BLAST results are available for this feature:
BLAST of Synaptogyrin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SYNGR21.126e-1437.14synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499][more]
SYNGR21.126e-1437.14synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499][more]
SYNGR22.898e-1435.96synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499][more]
SYNGR36.351e-1033.98synaptogyrin 3 [Source:HGNC Symbol;Acc:HGNC:11501][more]
SYNGR39.068e-1035.05synaptogyrin 3 [Source:HGNC Symbol;Acc:HGNC:11501][more]
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BLAST of Synaptogyrin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Synaptogyrin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Synaptogyrin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syngr3b2.965e-1435.14synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6... [more]
syngr3b3.050e-1435.14synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6... [more]
syngr3a5.674e-1331.53synaptogyrin 3a [Source:ZFIN;Acc:ZDB-GENE-050522-5... [more]
syngr2b1.054e-1026.05synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-1... [more]
syngr2b1.731e-1026.05synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-1... [more]
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BLAST of Synaptogyrin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syngr22.560e-1331.30synaptogyrin 2 [Source:NCBI gene;Acc:448480][more]
aif1l4.689e-1232.20allograft inflammatory factor 1-like [Source:Xenba... [more]
aif1l2.534e-1134.00allograft inflammatory factor 1-like [Source:Xenba... [more]
aif1l1.546e-1030.09allograft inflammatory factor 1-like [Source:Xenba... [more]
SYNGR34.064e-1030.92synaptogyrin 3 [Source:NCBI gene;Acc:100489723][more]
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BLAST of Synaptogyrin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Syngr25.433e-1635.71synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324][more]
Syngr27.100e-1635.71synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324][more]
Syngr21.948e-1435.14synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324][more]
Syngr31.295e-1034.95synaptogyrin 3 [Source:MGI Symbol;Acc:MGI:1341881][more]
Syngr24.404e-935.14synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324][more]
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BLAST of Synaptogyrin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O54980|SNG2_RAT2.130e-1535.71Synaptogyrin-2 OS=Rattus norvegicus OX=10116 GN=Sy... [more]
sp|O55101|SNG2_MOUSE4.966e-1535.71Synaptogyrin-2 OS=Mus musculus OX=10090 GN=Syngr2 ... [more]
sp|A7E3W5|SNG2_BOVIN1.406e-1434.48Synaptogyrin-2 OS=Bos taurus OX=9913 GN=SYNGR2 PE=... [more]
sp|O43760|SNG2_HUMAN5.406e-1437.14Synaptogyrin-2 OS=Homo sapiens OX=9606 GN=SYNGR2 P... [more]
sp|A8MWL6|SNG2L_HUMAN2.169e-1338.10Putative synaptogyrin-2 like protein OS=Homo sapie... [more]
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BLAST of Synaptogyrin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
U3F6711.666e-1436.77Synaptogyrin OS=Micrurus fulvius OX=8637 PE=2 SV=1[more]
G1KT113.041e-1437.42Synaptogyrin 2 OS=Anolis carolinensis OX=28377 GN=... [more]
V8P8P63.306e-1436.13Synaptogyrin OS=Ophiophagus hannah OX=8665 GN=SYNG... [more]
A0A2D4JAC23.465e-1436.77MARVEL domain-containing protein (Fragment) OS=Mic... [more]
A0A0B8RQ111.221e-1335.48Synaptogyrin OS=Boiga irregularis OX=92519 PE=3 SV... [more]
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BLAST of Synaptogyrin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syngr3a1.678e-1333.33synaptogyrin 3 [Source:NCBI gene;Acc:103035002][more]
syngr3a1.799e-1333.33synaptogyrin 3 [Source:NCBI gene;Acc:103035002][more]
syngr2b5.086e-1328.57synaptogyrin-2 [Source:NCBI gene;Acc:103034452][more]
syngr2b8.611e-1328.57synaptogyrin-2 [Source:NCBI gene;Acc:103034452][more]
syngr3b8.412e-1132.20synaptogyrin 3b [Source:ZFIN;Acc:ZDB-GENE-070822-6... [more]
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BLAST of Synaptogyrin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
syngr2b6.981e-1535.25synaptogyrin 2b [Source:ZFIN;Acc:ZDB-GENE-070424-1... [more]
ENSPMAT00000006063.15.085e-1233.79pep scaffold:Pmarinus_7.0:GL476493:599143:603638:1... [more]
ENSPMAT00000004662.16.111e-1033.95pep scaffold:Pmarinus_7.0:GL501065:8790:19293:1 ge... [more]
ENSPMAT00000003034.13.380e-831.61pep scaffold:Pmarinus_7.0:GL485592:66:4677:1 gene:... [more]
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BLAST of Synaptogyrin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Synaptogyrin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Synaptogyrin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000016399.28.005e-1534.75synaptogyrin 3 [Source:NCBI gene;Acc:101166799][more]
SYNGR33.679e-1334.26synaptogyrin-3 [Source:NCBI gene;Acc:101164956][more]
ENSORLT00000009770.22.493e-1028.66synaptogyrin-2 [Source:NCBI gene;Acc:101171415][more]
syngr2b1.153e-927.73synaptogyrin-2 [Source:NCBI gene;Acc:101157351][more]
syngr1b1.879e-930.82synaptogyrin 1 [Source:NCBI gene;Acc:101173609][more]
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BLAST of Synaptogyrin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000031799.12.455e-104100.00SMESG000031799.1[more]
SMESG000051237.12.933e-1433.14SMESG000051237.1[more]
SMESG000063084.15.108e-1028.00SMESG000063084.1[more]
SMESG000063084.16.233e-1028.00SMESG000063084.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032422 ID=SMED30032422|Name=Synaptogyrin|organism=Schmidtea mediterranea sexual|type=transcript|length=584bp
GTTAGAAATAAAATTTGCTAATTTGAAATTTTGAAAATGGAAATTGAAGA
TAAGTATAAAATAATGTTGGTTGTTAATCGCTTTTTGACTTTAATATATT
CTTTAATTGTTTTGGTGTGTATTCTGAAAGCGGGCTACAACAGTGATGGA
TTATGTTCTATTTTCCTTTTTGATGAAAGTGCTTGCAATTTTGGAATAGC
GTTACCAGTTGTTGGAATTATCGCTTTATTTCTTTTCCTTGTTTTCGATT
TCACTTGTGAATCTATTCGTGATTTTACAAAGTTAAATATATTGTCAACA
TTGGAAATAATTTTTACCTTGATTTGGTCGTTTCTTTGGCTCGTGGGATT
TTGCTTATTGGTCAACAGATGGAATTCAAGGGGAAATAATAATGATATAC
CAGGATGGAGGATATCATCTATACAAGCTGCCATATCGTTTTCTTTCTTT
TCTATCTTTACATGGATTTATCAATTCATCTGGGCCATCAGACGATATCG
AATACGAGTTCGGAATTTTGAAGCTTATGATCAATTATAATTTCAACAGT
GATCAGACTATTATTATTATTATTATTTTATACA
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protein sequence of SMED30032422-orf-1

>SMED30032422-orf-1 ID=SMED30032422-orf-1|Name=SMED30032422-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp
MAACIDDILHPGISLLFPLEFHLLTNKQNPTSQRNDQIKVKIISNVDNIF
NFVKSRIDSQVKSKTRKRNKAIIPTTGNAIPKLQALSSKRKIEHNPSLL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR016579Synaptogyrin
IPR008253Marvel
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008253Marvel domainPFAMPF01284MARVELcoord: 12..148
e-value: 5.6E-11
score: 42.6
IPR008253Marvel domainPROSITEPS51225MARVELcoord: 6..155
score: 11.347
IPR016579SynaptogyrinPANTHERPTHR10838SYNAPTOGYRINcoord: 12..159
NoneNo IPR availableTMHMMTMhelixcoord: 83..105
NoneNo IPR availableTMHMMTMhelixcoord: 49..70
NoneNo IPR availableTMHMMTMhelixcoord: 12..34
NoneNo IPR availableTMHMMTMhelixcoord: 129..151