C4b binding protein beta chain
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032384 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of C4b binding protein beta chain vs. Ensembl Human
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 120.168 bits (300), Expect = 3.667e-27 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2855 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3309 HSP 2 Score: 107.457 bits (267), Expect = 4.082e-23 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2620 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 3096 HSP 3 Score: 99.3673 bits (246), Expect = 1.248e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2717 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 3130 HSP 4 Score: 98.5969 bits (244), Expect = 1.902e-20 Identity = 108/424 (25.47%), Postives = 161/424 (37.97%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN-LRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N L + + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 2441 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY----QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2833 HSP 5 Score: 62.3882 bits (150), Expect = 3.127e-9 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3155 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3330 HSP 6 Score: 58.5362 bits (140), Expect = 5.118e-8 Identity = 125/543 (23.02%), Postives = 185/543 (34.07%), Query Frame = 3
Query: 396 QCQPP--VQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY----------------EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+CQPP V +GD V+Y C GY L G C+ + L+ GS P C Q P +V S+ +I GY E Y I +E ++D ++ S G + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2257 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ---------CPANEVRTGSS----------GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG--QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2733 HSP 7 Score: 51.6026 bits (122), Expect = 5.548e-6 Identity = 61/256 (23.83%), Postives = 87/256 (33.98%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
VC + PPVQ NG S G + Y+C GY L C+ G P+C C P IP + F +V C++ + S + + +G P I +C P G + Y S C G+ IQ +T R C A+ WSG C C + P + +V + T + C G+ L G S R C + W G + C
Sbjct: 3091 VCKAVLCPQPPPVQ--NGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV--FC-GDPGIP---AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGST--------TRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3330
BLAST of C4b binding protein beta chain vs. Ensembl Human
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 120.168 bits (300), Expect = 3.714e-27 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2273 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 2727 HSP 2 Score: 107.457 bits (267), Expect = 3.672e-23 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2038 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 2514 HSP 3 Score: 99.3673 bits (246), Expect = 1.069e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2135 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 2548 HSP 4 Score: 98.9821 bits (245), Expect = 1.822e-20 Identity = 107/423 (25.30%), Postives = 159/423 (37.59%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 1859 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPL---GMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2251 HSP 5 Score: 62.3882 bits (150), Expect = 3.107e-9 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 2573 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 2748 HSP 6 Score: 53.1434 bits (126), Expect = 2.230e-6 Identity = 63/276 (22.83%), Postives = 94/276 (34.06%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEA 1190
VC + PPVQ NG S G + Y+C GY L C+ G P+C C P IP + F +V C++ + S + + +G P I +C P G + Y S C G+ IQ +T R C A+ WSG C C + P + +V + T + C G+ L G S R C + W G + C + P ++ F ++
Sbjct: 2509 VCKAVLCPQPPPVQ--NGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV--FC-GDPGIP---AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGST--------TRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKI-----PSDVFFVNSLWKG 2763 HSP 7 Score: 51.2174 bits (121), Expect = 7.570e-6 Identity = 109/467 (23.34%), Postives = 164/467 (35.12%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
Q C P +P Q + DDF+ G+ VK C GY + K + +++ CE S + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 1735 QLKKCQPPPAVP--QAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEGSSG---QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2151
BLAST of C4b binding protein beta chain vs. Ensembl Human
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 120.168 bits (300), Expect = 3.732e-27 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2856 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3310 HSP 2 Score: 107.457 bits (267), Expect = 4.189e-23 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2621 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 3097 HSP 3 Score: 99.3673 bits (246), Expect = 1.216e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2718 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 3131 HSP 4 Score: 98.5969 bits (244), Expect = 1.902e-20 Identity = 108/424 (25.47%), Postives = 161/424 (37.97%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN-LRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N L + + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 2442 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY----QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2834 HSP 5 Score: 62.3882 bits (150), Expect = 3.127e-9 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3156 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3331 HSP 6 Score: 58.5362 bits (140), Expect = 5.162e-8 Identity = 125/543 (23.02%), Postives = 185/543 (34.07%), Query Frame = 3
Query: 396 QCQPP--VQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY----------------EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+CQPP V +GD V+Y C GY L G C+ + L+ GS P C Q P +V S+ +I GY E Y I +E ++D ++ S G + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ---------CPANEVRTGSS----------GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG--QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2734 HSP 7 Score: 51.6026 bits (122), Expect = 5.643e-6 Identity = 61/256 (23.83%), Postives = 87/256 (33.98%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
VC + PPVQ NG S G + Y+C GY L C+ G P+C C P IP + F +V C++ + S + + +G P I +C P G + Y S C G+ IQ +T R C A+ WSG C C + P + +V + T + C G+ L G S R C + W G + C
Sbjct: 3092 VCKAVLCPQPPPVQ--NGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV--FC-GDPGIP---AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGST--------TRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
BLAST of C4b binding protein beta chain vs. Ensembl Human
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 120.168 bits (300), Expect = 3.732e-27 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2856 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3310 HSP 2 Score: 107.457 bits (267), Expect = 4.189e-23 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2621 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 3097 HSP 3 Score: 99.3673 bits (246), Expect = 1.216e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2718 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 3131 HSP 4 Score: 98.5969 bits (244), Expect = 1.902e-20 Identity = 108/424 (25.47%), Postives = 161/424 (37.97%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN-LRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N L + + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 2442 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY----QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2834 HSP 5 Score: 62.3882 bits (150), Expect = 3.127e-9 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3156 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3331 HSP 6 Score: 58.5362 bits (140), Expect = 5.162e-8 Identity = 125/543 (23.02%), Postives = 185/543 (34.07%), Query Frame = 3
Query: 396 QCQPP--VQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY----------------EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+CQPP V +GD V+Y C GY L G C+ + L+ GS P C Q P +V S+ +I GY E Y I +E ++D ++ S G + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ---------CPANEVRTGSS----------GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG--QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2734 HSP 7 Score: 51.6026 bits (122), Expect = 5.643e-6 Identity = 61/256 (23.83%), Postives = 87/256 (33.98%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
VC + PPVQ NG S G + Y+C GY L C+ G P+C C P IP + F +V C++ + S + + +G P I +C P G + Y S C G+ IQ +T R C A+ WSG C C + P + +V + T + C G+ L G S R C + W G + C
Sbjct: 3092 VCKAVLCPQPPPVQ--NGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV--FC-GDPGIP---AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGST--------TRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
BLAST of C4b binding protein beta chain vs. Ensembl Human
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 120.168 bits (300), Expect = 4.454e-27 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2717 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3171 HSP 2 Score: 107.071 bits (266), Expect = 4.661e-23 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2482 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 2958 HSP 3 Score: 99.3673 bits (246), Expect = 1.353e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2579 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 2992 HSP 4 Score: 98.5969 bits (244), Expect = 2.190e-20 Identity = 108/424 (25.47%), Postives = 161/424 (37.97%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN-LRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N L + + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 2303 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY----QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2695 HSP 5 Score: 62.3882 bits (150), Expect = 3.394e-9 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3017 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3192 HSP 6 Score: 58.151 bits (139), Expect = 6.206e-8 Identity = 125/543 (23.02%), Postives = 185/543 (34.07%), Query Frame = 3
Query: 396 QCQPP--VQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY----------------EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+CQPP V +GD V+Y C GY L G C+ + L+ GS P C Q P +V S+ +I GY E Y I +E ++D ++ S G + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2119 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ---------CPANEVRTGSS----------GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG--QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2595 HSP 7 Score: 51.6026 bits (122), Expect = 5.775e-6 Identity = 61/256 (23.83%), Postives = 87/256 (33.98%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
VC + PPVQ NG S G + Y+C GY L C+ G P+C C P IP + F +V C++ + S + + +G P I +C P G + Y S C G+ IQ +T R C A+ WSG C C + P + +V + T + C G+ L G S R C + W G + C
Sbjct: 2953 VCKAVLCPQPPPVQ--NGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV--FC-GDPGIP---AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGST--------TRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3192
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Match: lev-9 (pep chromosome:WBcel235:X:6286129:6291579:-1 gene:WBGene00002976.1 transcript:T07H6.5c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lev-9) HSP 1 Score: 193.356 bits (490), Expect = 5.262e-53 Identity = 169/578 (29.24%), Postives = 241/578 (41.70%), Query Frame = 3
Query: 291 KACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHS-ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSN-RDDFKNGEDVKIICQNGYED-PYKSHIIAKC-----NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXX----XXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
K C A+ DC R + C+CD CGL C+ C P NG + L G EY C GY L G +R CQAN S S+P C Q C P IP+ VHD S+ ++ +V C GY K I+KC N +W ++C+ ++C D +NG + + Y CN GF + +T RQC ++G+W+ + A C A C S P +G+V+G T S+ T+ C GY+L G R C EG W G+ C C P + + T+ GA A ++C T G S C E G P P+CL C+ + + K+ + + G+ V +CN +E N D C N +W+ +P C +C PP + ++ + F H S+A+Y C+ GY+ R + + IKC G WTK P C P T G+I L G K R + ++C L GP A C+NG W P P C H + L+ R
Sbjct: 33 KECIADEDC----KRNKRCMCDGE-CGLSCVNPIAMCHPLPNIENGFIRTAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCRLQLK-CGPPPEIPFA-VHDGSSFSGEYDLDAEVAYNCIPGYHKFNAKGLSISKCLLNRKNVAQWFGPDLRCKARACPDPGDIENG-LREGDTFEYPHHVKYSCNPGFLLVGSTS--------RQCSSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFGAVAVFRCLETMTHEG-ASKAKCME----DGQWSAPIPRCLASCRVPHIQNGKIRDKSEGQL--------IASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYH-PNRNNQI--------IKCLYGEWTKDGPPMKCLPSWCEHPSKTYGTLPGGQILLEGILGAYEFQSYIQKVEEGRAISFQCGKGNYLIGPPKATCVNGEWMPKVSPKCVSQTHPMIEGKILWDR 572
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Match: lev-9 (pep chromosome:WBcel235:X:6286453:6291732:-1 gene:WBGene00002976.1 transcript:T07H6.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lev-9) HSP 1 Score: 192.971 bits (489), Expect = 7.418e-53 Identity = 169/578 (29.24%), Postives = 241/578 (41.70%), Query Frame = 3
Query: 291 KACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHS-ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSN-RDDFKNGEDVKIICQNGYED-PYKSHIIAKC-----NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXX----XXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
K C A+ DC R + C+CD CGL C+ C P NG + L G EY C GY L G +R CQAN S S+P C Q C P IP+ VHD S+ ++ +V C GY K I+KC N +W ++C+ ++C D +NG + + Y CN GF + +T RQC ++G+W+ + A C A C S P +G+V+G T S+ T+ C GY+L G R C EG W G+ C C P + + T+ GA A ++C T G S C E G P P+CL C+ + + K+ + + G+ V +CN +E N D C N +W+ +P C +C PP + ++ + F H S+A+Y C+ GY+ R + + IKC G WTK P C P T G+I L G K R + ++C L GP A C+NG W P P C H + L+ R
Sbjct: 33 KECIADEDC----KRNKRCMCDGE-CGLSCVNPIAMCHPLPNIENGFIRTAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCRLQLK-CGPPPEIPFA-VHDGSSFSGEYDLDAEVAYNCIPGYHKFNAKGLSISKCLLNRKNVAQWFGPDLRCKARACPDPGDIENG-LREGDTFEYPHHVKYSCNPGFLLVGSTS--------RQCSSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFGAVAVFRCLETMTHEG-ASKAKCME----DGQWSAPIPRCLASCRVPHIQNGKIRDKSEGQL--------IASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYH-PNRNNQI--------IKCLYGEWTKDGPPMKCLPSWCEHPSKTYGTLPGGQILLEGILGAYEFQSYIQKVEEGRAISFQCGKGNYLIGPPKATCVNGEWMPKVSPKCVSQTHPMIEGKILWDR 572
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Match: lev-9 (pep chromosome:WBcel235:X:6281847:6291579:-1 gene:WBGene00002976.1 transcript:T07H6.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lev-9) HSP 1 Score: 193.356 bits (490), Expect = 2.096e-51 Identity = 169/578 (29.24%), Postives = 241/578 (41.70%), Query Frame = 3
Query: 291 KACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHS-ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSN-RDDFKNGEDVKIICQNGYED-PYKSHIIAKC-----NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXX----XXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
K C A+ DC R + C+CD CGL C+ C P NG + L G EY C GY L G +R CQAN S S+P C Q C P IP+ VHD S+ ++ +V C GY K I+KC N +W ++C+ ++C D +NG + + Y CN GF + +T RQC ++G+W+ + A C A C S P +G+V+G T S+ T+ C GY+L G R C EG W G+ C C P + + T+ GA A ++C T G S C E G P P+CL C+ + + K+ + + G+ V +CN +E N D C N +W+ +P C +C PP + ++ + F H S+A+Y C+ GY+ R + + IKC G WTK P C P T G+I L G K R + ++C L GP A C+NG W P P C H + L+ R
Sbjct: 33 KECIADEDC----KRNKRCMCDGE-CGLSCVNPIAMCHPLPNIENGFIRTAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCRLQLK-CGPPPEIPFA-VHDGSSFSGEYDLDAEVAYNCIPGYHKFNAKGLSISKCLLNRKNVAQWFGPDLRCKARACPDPGDIENG-LREGDTFEYPHHVKYSCNPGFLLVGSTS--------RQCSSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFGAVAVFRCLETMTHEG-ASKAKCME----DGQWSAPIPRCLASCRVPHIQNGKIRDKSEGQL--------IASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYH-PNRNNQI--------IKCLYGEWTKDGPPMKCLPSWCEHPSKTYGTLPGGQILLEGILGAYEFQSYIQKVEEGRAISFQCGKGNYLIGPPKATCVNGEWMPKVSPKCVSQTHPMIEGKILWDR 572 HSP 2 Score: 56.9954 bits (136), Expect = 4.896e-8 Identity = 47/195 (24.10%), Postives = 71/195 (36.41%), Query Frame = 3
Query: 732 WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG---VWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC--IVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
W + +C C + T+ +Y +A C+ GF + ++N C G WS D C + CP L PP NG +G NT I C Y L G C +G W + C R+ G P +A + + G + + C S++ + + L C S LP
Sbjct: 1154 WSHSAPRCVAAHCPAVFVNGTRMTVTVTSYRTGGVAHFKCHKGFTL------IGEQN--LHCTTQGTWSHDFPYCNVVHCPPLLPPANGHFIGEPKEINTKGDIVLLGCLPNYMLTGGDFSVCQADGEWSEIKTKCDGYCRHPGQPDHGATTTIAKDYYSIGEKIVFYCPSQNYKLSSDNVLVCISPGQWSRRLP 1340 HSP 3 Score: 51.2174 bits (121), Expect = 2.777e-6 Identity = 54/255 (21.18%), Postives = 88/255 (34.51%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHS--ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK---TFKC-KEGYQLHGSHLRKCTREGNWDGSNSTCIVRN 1142
+C P+ P N + S L VG +++C G++++G C + S S P C + P + ++ G C G+ + ++ G W +D C C L P NG ++ + I D + C + CQADG+WS C C P++G + SI F C + Y+L ++ C G W C+ N
Sbjct: 1105 KCLLPIGPTNLQVDLSSPTLFVGTVAQFSCPPGFSVEGSAVSTCLEDATWSHSAPRC-----VAAHCPAVFVNGTRMTVTVTSYRTGGVAHFKCHKGFTLIGEQNLHCTTQGT-WSHDFPYCNVVHCPPLLPPANG------HFIGEPKEINTKGDIVLLGCLPNYMLTGGDFSVCQADGEWSEIKTKCDG-YCRHPGQPDHGATTTIAKDYYSIGEKIVFYCPSQNYKLSSDNVLVCISPGQWSRRLPLCLPSN 1346
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Match: C54G4.4 (pep chromosome:WBcel235:I:7996728:8003179:-1 gene:WBGene00008314.1 transcript:C54G4.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C54G4.4) HSP 1 Score: 63.5438 bits (153), Expect = 4.135e-10 Identity = 65/273 (23.81%), Postives = 107/273 (39.19%), Query Frame = 3
Query: 690 PYKSHIIAKCNGNEWKYDPIK--------CEKK-----SCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTV--NSIKTFKCKEGYQL-------HGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKC 1442
P S + EWK+ P C+ K S G E K T +++Y ++ C+ G+ + +R+C +G+W+G C C + + G + + T S ++C G+ L + S R C +G W GS TC + +CG PP I +V E++T + A Y C LIG S L CG+ + W P P C ++ + + H N+ +++ + V V C
Sbjct: 443 PSASEAVLLARPLEWKWVPASQTAWNSFLCQSKPKFCTSPGVGEATK--VTFSSHSYAIGTLCFYSCDSGYDLHGIR--------QRECAENGRWTGSIPNCYRKSCGAVRQWKFGRIKLLNKTTLFESEVEYECSNGWHLANSPSPSYRSLRRVCQSDGIWSGSEPTCELVDCGRPPLIANGRVDVESSTFESAANYTCHQGFRLIGPES-LMCGD---RGEWQPA-TPFCYDIATLQEIRGSTSHEHSNDNSSDSTIAMAVLASVIVAILC 700
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Match: F36H2.3 (pep chromosome:WBcel235:I:9251838:9261657:-1 gene:WBGene00009500.1 transcript:F36H2.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F36H2.3) HSP 1 Score: 61.6178 bits (148), Expect = 1.985e-9 Identity = 112/578 (19.38%), Postives = 187/578 (32.35%), Query Frame = 3
Query: 390 DLQCQPPVQPVNGHANHS------ILLVGDQVEYTCKSGYALKGPRKRYCQANL----------RLSGSEP-ECTDQTDLCFS-APYIPYTQVHDNSNRDDFKNGEDVKIICQNG---------YEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPK------NGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG------PPPEIVFAKVAYEAT-----THGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPK----PEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWN--FIPRCVEAACSARPPS---MKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIK--CNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPI-HNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHD 1955
+QC + P+ G +S G V +C +G A+ G C + + GS +C+ T + A Y P++ + F +G + C G + I+ C+G +C L P +G T + + IA C++G +I +T G + + C ++ P + + V ++ + T C L GS C+ G W + +C G PP V A + Y + T G+ A C + T+IG TS C S W P C P S + + + + + GT V C GY L+ + + C + W+ + C++ +R + T + + + G + LR D +T D C G W+ CQ I + + T + + P VV C Y G + C NG W+PP + CE I ++
Sbjct: 990 GIQCTAMIAPLGGSVIYSNGGTMGPFPSGTTVTGSCTNGGAITGASTATCSNGMWNPTFLGTCSLIGGSTTGQCSALTIPSGAQATYSPFSL-----STTSFTSGTVATVTCTTGGSMLGTSTCTNGLWSPAIMGTCSGTG--------TGNTCSALTRPVGETVTYDGTTSFATTFNSGVIARVTCSNGTQIGQSTCLVGQWTPAITATCSGSSTAVGSQCIGVIVPTNAQVTYSDGSMVLHSAGTTATLTCLNSATLTGSSYSSCS-NGVWTPTLGSCTSSGTGTGPCYTPPLTPVGATLTYSSGYFAPWTAGSTATMSCPAGQTVIG-TSISYC----TNSAWSPALGSCSGSSVGQGCTPLSAFSGT--LTNGRMSYSPTITATIPVGTMVNIVCYAGYTLSGNSISTCTSSGWSPSTVGSCIQQGVLSRVSNQNCAAMDTPNHGTFSYSVAGSF--TTGTIVTLRCD-TNYAATNGDTSAICTNGVWSPKSLAMCQRTLKEVIGASCPAGIPAVLAATMTYSNGQLLGPYPAATVVTATCQAGYIPTGIMTSTCTNGLWTPPSLGLCELIGNE 1543
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Match: Hasp (gene:FBgn0032797 transcript:FBtr0081281) HSP 1 Score: 190.66 bits (483), Expect = 2.084e-50 Identity = 154/563 (27.35%), Postives = 242/563 (42.98%), Query Frame = 3
Query: 363 LCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT----AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV--FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVY----IHENNKTTNFIMH------------------DEVTHGTHVRAKCNFGYELNSDIL--PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLK-GPKIAVCLNGHWSPPQMPTCEFIMH 1952
+CG C++ D +C QP G + G + Y C GY + G + R CQA+ +G+EP C Q C P I + + ++ F V+ C GY ++ +A N W I+CE +SCG+ DP G YTY C G+++ +++ CQ+DG W+ + T+++CP P+NG+ NS+ +++C+ GY L G +C + W G+ TC NCG P + + + T GA ++C+ + G S + ++D + W P+CL C + VY I + N TT I+H ++V HGT + KC+ YE +L P C NG+W+ IPRCV A C + P K+ V +H AR+ C G+ + + T + + C+ GNWT T C C+ P NG++ L+G K ++N+ + Y+C Y L+ GP A C+ G W P +P C H
Sbjct: 109 VCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC-KQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHA-GECYTYGCKITYNCGTGYELVGKHERY--------CQSDGSWTPKELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVC--QIDGR--WR-NALPECLAPCVVPTISQGNVYPIEIITDENGTT--IVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCNNGTWSIIPRCVPARCKSMPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGE-TPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQH 653
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Match: Hasp (gene:FBgn0032797 transcript:FBtr0302108) HSP 1 Score: 190.66 bits (483), Expect = 2.528e-50 Identity = 154/563 (27.35%), Postives = 242/563 (42.98%), Query Frame = 3
Query: 363 LCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT----AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV--FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVY----IHENNKTTNFIMH------------------DEVTHGTHVRAKCNFGYELNSDIL--PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLK-GPKIAVCLNGHWSPPQMPTCEFIMH 1952
+CG C++ D +C QP G + G + Y C GY + G + R CQA+ +G+EP C Q C P I + + ++ F V+ C GY ++ +A N W I+CE +SCG+ DP G YTY C G+++ +++ CQ+DG W+ + T+++CP P+NG+ NS+ +++C+ GY L G +C + W G+ TC NCG P + + + T GA ++C+ + G S + ++D + W P+CL C + VY I + N TT I+H ++V HGT + KC+ YE +L P C NG+W+ IPRCV A C + P K+ V +H AR+ C G+ + + T + + C+ GNWT T C C+ P NG++ L+G K ++N+ + Y+C Y L+ GP A C+ G W P +P C H
Sbjct: 109 VCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC-KQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHA-GECYTYGCKITYNCGTGYELVGKHERY--------CQSDGSWTPKELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVC--QIDGR--WR-NALPECLAPCVVPTISQGNVYPIEIITDENGTT--IVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCNNGTWSIIPRCVPARCKSMPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGE-TPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQH 653 HSP 2 Score: 50.447 bits (119), Expect = 5.913e-6 Identity = 60/256 (23.44%), Postives = 95/256 (37.11%), Query Frame = 3
Query: 789 KNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPEL-----SPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP--PEIVFAK--VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSW-NFIPRCV 1520
+ G + N+ + A+ C +G + ++ F C G WS +C ++ C ++ S + V + V F C GY L G C G W TC+ C P P+ +A+ Y A G ++ C + G+ + C + SG L PKC+ C P V S ++ + F G + C+ G +L S +L NG W + IP CV
Sbjct: 1414 RRGLIVNTNDTKLSTRALLSCANGNSLIGASELF--------CLPSGNWSAPLPVCESVECGDIPLGMGSNASSPRVSVLSREVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSAPYRA---GDVVQFNCNPEYMMQGQ-PIIACQDNARWSGGL----PKCVQACSYPGTVISGRM------SSVKFYY----AIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCV 1643
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Match: Hasp (gene:FBgn0032797 transcript:FBtr0302107) HSP 1 Score: 190.66 bits (483), Expect = 2.528e-50 Identity = 154/563 (27.35%), Postives = 242/563 (42.98%), Query Frame = 3
Query: 363 LCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT----AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV--FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVY----IHENNKTTNFIMH------------------DEVTHGTHVRAKCNFGYELNSDIL--PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLK-GPKIAVCLNGHWSPPQMPTCEFIMH 1952
+CG C++ D +C QP G + G + Y C GY + G + R CQA+ +G+EP C Q C P I + + ++ F V+ C GY ++ +A N W I+CE +SCG+ DP G YTY C G+++ +++ CQ+DG W+ + T+++CP P+NG+ NS+ +++C+ GY L G +C + W G+ TC NCG P + + + T GA ++C+ + G S + ++D + W P+CL C + VY I + N TT I+H ++V HGT + KC+ YE +L P C NG+W+ IPRCV A C + P K+ V +H AR+ C G+ + + T + + C+ GNWT T C C+ P NG++ L+G K ++N+ + Y+C Y L+ GP A C+ G W P +P C H
Sbjct: 109 VCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC-KQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHA-GECYTYGCKITYNCGTGYELVGKHERY--------CQSDGSWTPKELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVC--QIDGR--WR-NALPECLAPCVVPTISQGNVYPIEIITDENGTT--IVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCNNGTWSIIPRCVPARCKSMPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGE-TPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQH 653 HSP 2 Score: 50.447 bits (119), Expect = 5.913e-6 Identity = 60/256 (23.44%), Postives = 95/256 (37.11%), Query Frame = 3
Query: 789 KNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPEL-----SPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP--PEIVFAK--VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSW-NFIPRCV 1520
+ G + N+ + A+ C +G + ++ F C G WS +C ++ C ++ S + V + V F C GY L G C G W TC+ C P P+ +A+ Y A G ++ C + G+ + C + SG L PKC+ C P V S ++ + F G + C+ G +L S +L NG W + IP CV
Sbjct: 1414 RRGLIVNTNDTKLSTRALLSCANGNSLIGASELF--------CLPSGNWSAPLPVCESVECGDIPLGMGSNASSPRVSVLSREVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSAPYRA---GDVVQFNCNPEYMMQGQ-PIIACQDNARWSGGL----PKCVQACSYPGTVISGRM------SSVKFYY----AIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCV 1643
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Match: Hasp (gene:FBgn0032797 transcript:FBtr0081280) HSP 1 Score: 190.66 bits (483), Expect = 2.770e-50 Identity = 154/563 (27.35%), Postives = 242/563 (42.98%), Query Frame = 3
Query: 363 LCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT----AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV--FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVY----IHENNKTTNFIMH------------------DEVTHGTHVRAKCNFGYELNSDIL--PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLK-GPKIAVCLNGHWSPPQMPTCEFIMH 1952
+CG C++ D +C QP G + G + Y C GY + G + R CQA+ +G+EP C Q C P I + + ++ F V+ C GY ++ +A N W I+CE +SCG+ DP G YTY C G+++ +++ CQ+DG W+ + T+++CP P+NG+ NS+ +++C+ GY L G +C + W G+ TC NCG P + + + T GA ++C+ + G S + ++D + W P+CL C + VY I + N TT I+H ++V HGT + KC+ YE +L P C NG+W+ IPRCV A C + P K+ V +H AR+ C G+ + + T + + C+ GNWT T C C+ P NG++ L+G K ++N+ + Y+C Y L+ GP A C+ G W P +P C H
Sbjct: 109 VCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPAC-KQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHA-GECYTYGCKITYNCGTGYELVGKHERY--------CQSDGSWTPKELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVC--QIDGR--WR-NALPECLAPCVVPTISQGNVYPIEIITDENGTT--IVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCNNGTWSIIPRCVPARCKSMPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGE-TPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQH 653 HSP 2 Score: 50.447 bits (119), Expect = 5.763e-6 Identity = 60/256 (23.44%), Postives = 95/256 (37.11%), Query Frame = 3
Query: 789 KNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPEL-----SPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP--PEIVFAK--VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSW-NFIPRCV 1520
+ G + N+ + A+ C +G + ++ F C G WS +C ++ C ++ S + V + V F C GY L G C G W TC+ C P P+ +A+ Y A G ++ C + G+ + C + SG L PKC+ C P V S ++ + F G + C+ G +L S +L NG W + IP CV
Sbjct: 1413 RRGLIVNTNDTKLSTRALLSCANGNSLIGASELF--------CLPSGNWSAPLPVCESVECGDIPLGMGSNASSPRVSVLSREVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSAPYRA---GDVVQFNCNPEYMMQGQ-PIIACQDNARWSGGL----PKCVQACSYPGTVISGRM------SSVKFYY----AIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCV 1642
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Match: fw (gene:FBgn0001083 transcript:FBtr0112806) HSP 1 Score: 105.145 bits (261), Expect = 5.373e-23 Identity = 103/400 (25.75%), Postives = 151/400 (37.75%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH--GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPK------PEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTH--GTHVRAKCNFGYELNSDILPACYN-GSWN-FIPRCVEAACSA 1538
C +D P ++ + H + G Y+C Y L G R C + SG +PEC D C I V N D + G +C+ GY ++ II+ G EW C CG P G + N T N K +C D + D C +GKWSG+ +C + C S P V+G V+S + C G+ +HG+ + +C G W C +CG I + Y T G++ + C L G TC E S PK PEPK H + ++Y +T+ + T+ G + +C GY++ + L C + G W+ IP CV C A
Sbjct: 41 TCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMD-GWSGKQPECL--VDWCPDPQPIAGGDVRFN----DKRAGSTATYVCEPGYVLVGEA-IISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTT-------TVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLK-RTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGA 424 HSP 2 Score: 98.5969 bits (244), Expect = 6.288e-21 Identity = 83/307 (27.04%), Postives = 126/307 (41.04%), Query Frame = 3
Query: 453 VGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTD-----------------QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY--EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPE 1310
VG +V ++C + L G KR C + S + P+C + D + I ++ N+ + +K G K C+ GY+ +A C + +W +C CG E NG+ + N TY A+ + CN FK+ + RR C G WS + C ++C + EN V V S+ TFKC +G + G+ R C + G W G + TC +CG P I +V ++T +G AEY C IG+ C E SG P+ E
Sbjct: 302 VGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQT-YKIGALAKYRCERGYK--MVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVS--------RRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQY-LRKCTEDGAWSGKQPRCE 596 HSP 3 Score: 65.855 bits (159), Expect = 9.795e-11 Identity = 83/321 (25.86%), Postives = 133/321 (41.43%), Query Frame = 3
Query: 1005 MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARP-PSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCEFI 1946
MG T+ + C +G+ L G R+C +G W GS+ TC +CG PE+ F + + E T+ G A Y C TLIG + TC GW K +P+CL+ P A + N+K G+ C GY L + + +C G W+ P C C A P+ + + + +S+ +Y C +++ DG L +G W+ + P C+ C P P +++G +H++ ++Y C P + + G + CL+ G WS P CE+I
Sbjct: 1 MGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNEN-RTCA----MDGWSGK-QPECLVDWCPDPQPIAGGDVRFNDKRA----------GSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTTTVNSVVKYECDEDHWL----DGQSELYCT-----REGKWSGEAPV--CELVTCETPSVPSGS--FVIGYDYN----------VHSK-IQYNCDPGHIMHGTPVLECLDSGEWS-ADAPYCEYI 280
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Match: svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-110726-1]) HSP 1 Score: 122.479 bits (306), Expect = 4.305e-28 Identity = 141/572 (24.65%), Postives = 219/572 (38.29%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD--DFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-----------KLEDPKNGRTMY-------NNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTC---GEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW------------SPPQMPTCEFIMHDELPISWLYYRSDD 1994
++C P + NG +S L + Y C+ GY ++GP C N + P C + +P P DN + D K G + C G+ +H+ C + W KC CG K+++ M +N++ + S+ C+ G++I + C+ DG W+G +CT C PENG VM + + S+ + C EGY+L+G +R+C W C+ +CG P I +V ++ Y+C S L G + TC G+ DNK+ P C +V + + ++ + D+ T G + CN G+ L C NGSWN + P+C+ A C +PPS++ V ++ + RY C GY + G TL D G W P C C P +G YL G S + +V+Y C P Y + G I C G W SPP + D + +++R DD
Sbjct: 2498 VKCAAPKEIPNGSVRYSKLQFSQSITYFCQRGYRIQGPETLTCLENGQWDQEAPTCVP----IYCSPPKPI----DNGFVEGRDRKFGVTIFYSCFPGFLLVGNNHLT--CEDHGWSSSEPKCVLADCGLPPHIDFGDYSKVQELSAEYDMVTSQQLPVDNSFLHGSLVKYHCHSGYEI--------NGAIMLMCREDGTWNGTAPMCTPAQCEAPPSPENGSVMVTDSALGSLAEYSCAEGYELNGQTIRQCISGQQWSDDAPRCLPISCGNPGGIANGEVIGKSFHFKELIHYECHSGFVLEGVET-RTCQVDGKWDNKA-------PLCK------EVSCGRPVVSKD----VLVRGDDHTFGKRLLFSCNLGFILLGAPTIVCLANGSWNEVPPKCLPANC-GQPPSIENGRVTGTDYGYNGMVRYACDIGYVLT----GNPTLICRAD-----GLWDDPPPR-CDIITCDPPEDISHG--YLNGSSFN-----------FDDIVEYICFPGYEVVGSPILRCAAEGVWLGQVPECRPCVCSPPVFKYGSILGRDHTCGASIWFRCDD 3009 HSP 2 Score: 121.709 bits (304), Expect = 8.503e-28 Identity = 142/539 (26.35%), Postives = 219/539 (40.63%), Query Frame = 3
Query: 330 DRAQLCVCDSYLCG--LVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYN-NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELN-SDILPACYNGSWNFIPR---CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWS 1916
D + +C C + G C E ++C+ P P G + ++G +V ++CK GY L G + C P C L P +P + +N F G V C+ GY P + I ++C + +W +P C+ +CG E P Y N Y+S C +G+++Q + QC++ G+W+ +C + C + P ++ + G T+ S + CK+GY L G+ ++C GNW ++S C+ R+CGPPP++ A G A Y C T G + L C N G P+ + HC H + I + T V KC G+ LN + L G W P C+ CS +P S++ V + ++ Y C GY+I K + S G W +PT CQP C PP NG ++ GQ + ++N V Y C+ YRL G C+ N WS
Sbjct: 1765 DGSHICTCIAPYSGDGRNCTE-PVKCKDPGVPEFGQREGTNFIMGSEVVFSCKEGYELIGSSQLTCTEEGFWKQDVPYCKA---LSCPHPTLPKYGILKGAN---FTYGSKVTFSCEKGYV-PLEP-IESQCQSDLKWSREPHICQPITCG--EPPVVDYAEYTLNGKIYRSTLSYTCIEGYRLQGAME--------LQCESSGEWTSPPPMCARVDCGKPPPLKDAVIKGDNFTLGSKIYYICKDGYTLLGAETQECLPSGNWTRNSSQCVPRSCGPPPQVDHALPDTGHQLFGDIAIYFCDDGYT-AGNNTKLFC----NAQGVWAPPDGFGIPHCIANFCQRPPDLPH---AILDSINKPKYASNTEVSYKCEEGFVLNTTGTLKCLIGGEWTPSPSDIGCMPVRCS-KPESIEKGYVSGNNYGFGAVIAYSCDKGYFIRGEKKRICKAS---------GEWGGVLPT--CQPISCPSPPRLANG--FIQGQIRKNSY-------VYNSKVTYACNDGYRLTGKPERTCMANKQWS 2255 HSP 3 Score: 115.931 bits (289), Expect = 4.747e-26 Identity = 133/522 (25.48%), Postives = 209/522 (40.04%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI---CTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL--NSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWS 1916
CM + +C P G+ + + G + Y+C GY ++G +KR C+A+ G P C Q C S P + + ++ + V C +GY K N + + C +C D KNG +Y+ + ++F CN+G+++ T C G W D +I C+ + CPE EN V+ ++ + C+EGY LHG+ +CT W+ S C CGPPPE+ F + + G+ Y C TL E S + C N S KP P+C+ + C H + + + + + C GY++ NS +L +G W IP C C+A P + +VR+ L+ Y+C GY R G ETL+ + G W + PT C P C+ P NG ++ G+ + +T + Y C P + L G C + WS
Sbjct: 2141 CMPV--RCSKPESIEKGYVSGNNYGFGAVIAYSCDKGYFIRGEKKRICKASGEWGGVLPTC--QPISCPSPPRLANGFIQGQIRKNSYVYNSKVTYACNDGYRLTGKPERTCMANKQWSNSNSLVCVLLTCPTPPDIKNG--LYHGSTFEVGSKVEFVCNEGYELIGDT--------VWTCLKFGNW--DKSIIPRCSPVQCPEPPLEENHLVLRGLDSDSGTVELSCEEGYVLHGARTLRCTPSQEWNDSFPVCKQVFCGPPPEVAFGDPSDTQSYFGSVVTYSCMDGFTLRKEGS-VHCQANGNWS----KPYPQCIPVECP-----------HPEDIPNGIVDVQGLMYLSTAVYSCKAGYDILGNSTVLCG-QSGQWIGGIPVCHPVKCAA-PKEIPNGSVRYSKLQFSQSITYFCQRGY----RIQGPETLTCL-----ENGQWDQEAPT--CVPIYCSPPKPIDNG--FVEGRDRKFGVT-----------IFYSCFPGFLLVGNNHLTCEDHGWS 2604 HSP 4 Score: 107.842 bits (268), Expect = 1.923e-23 Identity = 129/535 (24.11%), Postives = 197/535 (36.82%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPEN---GEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL---LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYN-GSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELPI 1967
+ + C P NG + + Y C SG+ L+G R CQ + + P C + + C P DD G+ + C G+ I+ NG+ W P KC +CG+ +NGR + +Y Y + C+ G+ + N C+ADG W C I C PPE+ G + G + I + C GY++ GS + +C EG W G C C PP + + T GA ++C ++G + + D W P P C P V +A + +T + + D VT+ +C GY L +C G W E PP + + L + S A+Y C G+ +A + D + S G W+K C+P L +T K + P+ V+ C P Y L+GP ++ C ++G WSPP I LPI
Sbjct: 2746 LPISCGNPGGIANGEVIGKSFHFKELIHYECHSGFVLEGVETRTCQVDGKWDNKAPLCKEVS--CGR----PVVSKDVLVRGDDHTFGKRLLFSCNLGFILLGAPTIVCLANGS-WNEVPPKCLPANCGQPPSIENGR-VTGTDYGYNGMVRYACDIGYVLT--------GNPTLICRADGLWDDPPPRCDIITC---DPPEDISHGYLNGSSFNFDDIVEYICFPGYEVVGSPILRCAAEGVWLGQVPECRPCVCS-PPVFKYGSILGRDHTCGASIWFRCDDGYKILGSSEAI----CDKGGVWSPG-VPICTRGRCSIPPPAVPNAVI-----QGSTAYTI-DTVTY------RCRPGYHLKGFPHISCGRLGRWGEPNLSCEPISCGVPPLISNAETVGAVLTYGSKAQYRCKEGFELATKTDSITCQS--------DGTWSKHGVR-CRPS-----------PCTLPTNLTHVVITGKQLTPVGGTVI-VSCRPGYYLEGPGLSECTVSGKWSPPLASCLPVICEKPLPI 3222 HSP 5 Score: 98.9821 bits (245), Expect = 9.525e-21 Identity = 92/380 (24.21%), Postives = 141/380 (37.11%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIA---IQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN 1502
+C PP P N S D V Y C+ GY LKG C R EP + + C P I + G + C+ G+E K+ I + W ++C C N T+ I + + C + + +C GKWS A C ++C + P NG V G+ + F C++G+ L G +R C + W G+ C +CGPPP + A + T+ + Y C+ ++L+ ++ LTC N S LP P + C+ D + E+N ++ G + CN GY L + L C NGSW+
Sbjct: 3033 ICTRGRCSIPPPAVP-NAVIQGSTAYTIDTVTYRCRPGYHLKGFPHISCGRLGRWG--EPNLSCEPISCGVPPLISNAETVGAV----LTYGSKAQYRCKEGFELATKTDSITCQSDGTWSKHGVRCRPSPC-----------TLPTNLTHVVITGKQLTPVGGTVIVSCRPGYYLEGPGLSECTVSGKWSPPLASCLPVICEKPLPILNGLVEGISYNYGDVVNFTCQQGFLLQGHSVRTCQGDKTWSGTQPVCAAVSCGPPPVVPNAVASSSGQTYKSIVSYTCRQGTSLV-DSQNLTCQA--NGSWSLPTPICEVPGGCEKI-TDLLNGKVQEHN----------LSSGRALEFHCNKGYTLQGESLVMCVGNGSWS 3380 HSP 6 Score: 90.8929 bits (224), Expect = 3.317e-18 Identity = 134/569 (23.55%), Postives = 201/569 (35.33%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE--NGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVD--NKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTH-GTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI----------------------------------ALRKDGMETLSTIFDIKCNKG---------------NWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHN----RVVKYECHPLYRLKGPKIAVCL-NGHWSPP 1922
C P NG + V Y C GY L G C+A+ P C D+ P P H N F + V+ IC GYE S I+ W +C C K G + ++ SI + C+DG+KI +++ DK G WS ICT C + PP N + G T++C+ GY L G C R G W N +C +CG PP I A+ T+G++A+Y+CK L +T +TC +K G +P P C L N T I ++T G V C GY L L C +G W+ + C+ C +P + V +S + + + C G+ + A+ +T +I C +G +W+ +PT C+ G T L + ++ HN R +++ C+ Y L+G + +C+ NG WS P
Sbjct: 2866 CGQPPSIENGRVTGTDYGYNGMVRYACDIGYVLTGNPTLICRADGLWDDPPPRC----DIITCDP--PEDISHGYLNGSSFNFDDIVEYICFPGYEV-VGSPILRCAAEGVWLGQVPECRPCVCSPPVF-KYGSILGRDHTCGASIWFR-CDDGYKILGSSEAICDKG--------GVWSPGVPICTRGRC-SIPPPAVPNAVIQGSTAYTIDTVTYRCRPGYHLKGFPHISCGRLGRWGEPNLSCEPISCGVPPLISNAETVGAVLTYGSKAQYRCKEGFELATKTDSITCQSDGTWSKHGVRCRPSP-CTL---------------PTNLTHVVITGKQLTPVGGTVIVSCRPGYYLEGPGLSECTVSGKWSPPLASCLPVICE-KPLPILNGLVEGISYNYGDVVNFTCQQGFLLQGHSVRTCQGDKTWSGTQPVCAAVSCGPPPVVPNAVASSSGQTYKSIVSYTCRQGTSLVDSQNLTCQANGSWS-LPTPICEVPG---------------GCEKITDLLNGKVQE-HNLSSGRALEFHCNKGYTLQGESLVMCVGNGSWSSP 3382 HSP 7 Score: 70.0922 bits (170), Expect = 9.060e-12 Identity = 109/506 (21.54%), Postives = 178/506 (35.18%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLV--GDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKC-------------EKKSCGKLED----------PKNGRT-----------------MYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
+V + ++ L + CP N+ W ++ + + C + L V+ H S V G +V+++C G+ L G + C + S +EP C + C P + + Q H +DF G V C+ G+ +S + NG +W +P C E SC + +GR N+ S + C +G+++ ++ + C +G W D C A+ CP + P+ G + G T S TF C++GY +C + W C CG PP + +A+ + + Y C L G L C SG P P C +VD K ++ I D T G+ + C GY L C +G+W +CV +C PP + ++ +A Y+C GY
Sbjct: 1582 YVLTPQQIRSLASSCPHDLQKGNVFAWPDFLGGVTGRVKTTSKSIFCADCPL-----VETSVPHLLSSSKAVSPGSKVQFSCSPGFYLVGEPVQLCLNRGQWSHAEPIC--ERVECGPPPDLEHGQYHG----EDFYAGSSVLYQCKPGFYLLGESKMQCTNNG-KWIGNPPACLDVDECSLGSECDEHASCQNTDGSHICTCIAPYSGDGRNCTEPVKCKDPGVPEFGQREGTNFIMGSEVVFSCKEGYELIGSS--------QLTCTEEGFWKQDVPYCKALSCPHPTLPKYGILKGANFTYGSKVTFSCEKGYVPLEPIESQCQSDLKWSREPHICQPITCGEPPVVDYAEYTLNGKIYRSTLSYTCIEGYRLQGAME-LQC----ESSGEWTSPPPMCA------RVDCGKPPPLKD----AVIKGDNFTLGSKIYYICKDGYTLLGAETQECLPSGNWTRNSSQCVPRSCGP-PPQVDHALPDTGHQLFGDIAIYFCDDGY 2051 HSP 8 Score: 65.0846 bits (157), Expect = 2.701e-10 Identity = 54/189 (28.57%), Postives = 81/189 (42.86%), Query Frame = 3
Query: 954 CTAILCPELSPPENGEVMG--VWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG--PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN 1502
C A++CP LSPPENG + N NS +C G+ L G +R C +G W G +C +R+C PP + + + + +C+ L G +TC SG P+P+C+ + C P +IH T +EV G + C +GY L D C G+W+
Sbjct: 368 CQAVVCPVLSPPENGFFIQNVCNNQFNSACGVRCLPGFDLQGDGIRLCQPDGTWSGVQPSCRIRSCPDLSPPHHGMLNCSERSAPYRLECLVRCEQGYRLQGRAR-ITCLANSQWSG----PQPRCVEVRCPPIVTLK---HIHLMPSTCG---ENEVRTGAVCQLSCPYGYSLIGDSKVKCLPTGNWS 545 HSP 9 Score: 62.7734 bits (151), Expect = 1.680e-9 Identity = 74/329 (22.49%), Postives = 128/329 (38.91%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTF------KCKEGYQLH-----GSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPK--CLLHCK 1334
+ + C+ P+ +NG GD V +TC+ G+ L+G R CQ + SG++P C + C P +P +S+ +K+ V C+ G ++ + NG+ PI C K+ D NG+ +N + +++ CN G+ +Q C +G WS +C P +G +G N ++ + C +G ++ G C + W ++ C +CGPP + V G Y C + T+ G + + +DN + W P K C HC+
Sbjct: 3212 LPVICEKPLPILNGLVEGISYNYGDVVNFTCQQGFLLQGHSVRTCQGDKTWSGTQPVCAAVS--CGPPPVVPNAVA--SSSGQTYKS--IVSYTCRQGTSLVDSQNLTCQANGSWSLPTPICEVPGGCEKITDLLNGKVQEHNLSSGRALEFH-CNKGYTLQ--------GESLVMCVGNGSWSSPFPVCLPK---PCPPLPHGWTVGSANATQTVFSVGQSVQVSCPKGQRVKSNQGKGIATLTCRSDQTWTPISAVCERVSCGPPLYVSNGVVRGAVFQFGDMVLYSCYAGFTMEGSSRSVC---LDNGT-WTQPPTCKAVCWRHCQ 3518 HSP 10 Score: 58.5362 bits (140), Expect = 3.372e-8 Identity = 49/181 (27.07%), Postives = 71/181 (39.23%), Query Frame = 3
Query: 753 CEKKSCGKLEDPKNGRTMYNN-NYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTF------KCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATT-------HGAQAEYKCKSRSTLIGET 1253
C+ C L P+NG + N N + S C GF +Q + R CQ DG WSG C CP+LSPP + G+ N + +C++GY+L G C W G C+ C PP + + +T GA + C +LIG++
Sbjct: 368 CQAVVCPVLSPPENGFFIQNVCNNQFNSACGVRCLPGFDLQ--------GDGIRLCQPDGTWSGVQPSCRIRSCPDLSPPHH----GMLNCSERSAPYRLECLVRCEQGYRLQGRARITCLANSQWSGPQPRCVEVRC--PPIVTLKHIHLMPSTCGENEVRTGAVCQLSCPYGYSLIGDS 534
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Match: csmd3a (CUB and Sushi multiple domains 3a [Source:ZFIN;Acc:ZDB-GENE-050419-118]) HSP 1 Score: 120.168 bits (300), Expect = 2.363e-27 Identity = 115/426 (27.00%), Postives = 158/426 (37.09%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLR--KCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSA--RPPSMKYSTV-RFLSLKHDSLARYYCHFGYYI 1631
C+ +D C P P NG + G V Y+C G LKG R CQ N S P C+ D + C P T H + + DF+ V C GYE + NG W C+ CG P NGR + T+ I C DG+ + +T RQCQA+G WSG CT I C E P NG G T+ TF C+ GY + CT G W+ C C PP I + G Y C S + + LTC SG +P+ C P + + +FI EV+ C Y C +G+W+ PRC+E + P + +Y ++ R K S+ + C G+ +
Sbjct: 2716 CIVVD--CGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGD----PGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGT-WSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGST--------TRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSC-SPGYELSFPAILTCVGNGTWSGEVPQ--------CLPKFCGDPGTPAFGSREGRSFIYQSEVSF------SCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLL 3111 HSP 2 Score: 109.768 bits (273), Expect = 4.208e-24 Identity = 141/548 (25.73%), Postives = 208/548 (37.96%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGH-ANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN----LRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EW-------KYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKH-----DSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
G + L C P P++G ++ + + V +TC GY L G C+ P C Q C +P V+ D+ G V C +GY K A C + W + + C LE + R + ++Y Y++ I C+ G+ + QC A+G WS + C I C +L+ P +G+ +G + + F C GY L GS +R+C G W G+ + C+ +CG P +IV +V E + Y+C S LIG +S C + N SG LP C P I+ F ++D V+ CN GY + C N W+ P C CS P + +++R ++H ++ Y C+ GYY+ G L+ C G W K P C C P +P NG + K V+Y C +LKG C LNGHWS P MP C
Sbjct: 2285 GFSIRYVALYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPAC--QAVSC----GVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGR-WRIVNGSHYEYRTKIIFTCDPGY--------YRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIG-SSVRICQQDHNWSGQLPI--------CVPISCGHPGSPIYGRTIGNGFNLNDVVSF------SCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSD--PGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLF----GSPVLT------CQPTGQWDK-PLPECIVVDCGHPGSPPNGLL-------------SGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAP-MPFCS 2775 HSP 3 Score: 97.8265 bits (242), Expect = 2.125e-20 Identity = 105/444 (23.65%), Postives = 168/444 (37.84%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY---NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + + C P P+ G + + D V ++C GY ++GP + CQAN + S P C + C S P IP + + +F G V C GY + S ++ +W +C CG P NG + + +T+ + C G +++ R CQ +G WS C ++ C + P +G + S F C GY+L GS R C G W G+ +C CG P +V + TT Y C L G T+ C SG P C L++C V + + E + T ++ C GY + ++ NG+WN +P C C+A PP + + + + Y C GY ++
Sbjct: 2580 VRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTC--KVVNC-SDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYL-FGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNG-LLSGDKFTFGATVRYSCTGGRQLK--------GESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTT-RQCQANGTWSG----TAPNCTLINCGEPGVPANGLRYGE-----------DFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTA-PPPISNGLLEGRDFEWGTSVSYSCSPGYELSF 2993 HSP 4 Score: 91.2781 bits (225), Expect = 2.342e-18 Identity = 105/422 (24.88%), Postives = 162/422 (38.39%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG----EVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+ C P +G + G +TC +GY L G R C ++ SG+E C C +P V+ ++F + V C +G+ S I + + N PI C SCG P GRT+ N + + CN G+ ++ + R QCQA+ +WS C + C + P N ++ T ++ + C GY L GS + C G WD CIV +CG P ++ + T GA Y C L GE+S TC +G P P C D H + ++F + + V C+ GYEL + C+ NG+W+ P C C P + + + + H + Y C GY ++
Sbjct: 2483 ISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCL--AGHC----GLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPI-CVPISCGHPGSPIYGRTI-GNGFNLNDVVSFSCNMGYVMEGPS--------RAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESS-RTC----QLNGHWSAPMPFCSGDSSGTCGDPGTPS-HGSRDESDFRIRSK------VHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVI--YSCMDGYLLS 2874 HSP 5 Score: 90.1225 bits (222), Expect = 5.240e-18 Identity = 145/599 (24.21%), Postives = 211/599 (35.23%), Query Frame = 3
Query: 228 KPECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG---RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI---VRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTL-----IGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVRF---LSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
+P C + S ++ P+G S TA C Y + C+ G + C P Q VNG D V Y C SG+ L G R CQ + SG P C + C P + ++ + + F + V C GY E P + A+C N +W P C+ +C P N + + N+T+ ++ CN G+ + + CQ G+W C + C P NG + G T + + C G QL G R C G+W C CG P +HG++ E + RS + +G F + + +G +P C KP Q + N + D T V C GY L+ C NG+W+ P C C P + + +R+ ++ + + C GY + E+ STI C P C+ CT PP NG LL D T V Y C P Y L P I C+ NG WS ++P C
Sbjct: 2477 RPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPIS--CGH----PGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSR----AQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSP--------VLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDP----------GTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSC----KPVQCGNPGT--PSNGRVYRL---DGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGE--PGVPANGLRYGEDFTIAQN--ITFMCQPGYTME-----AESFSTI---TCTGNGTWNAPVPFCKAVTCTAPPPISNG---LLEGRDFEWGTS----------VSYSCSPGYELSFPAILTCVGNGTWS-GEVPQC 3012 HSP 6 Score: 81.2629 bits (199), Expect = 3.063e-15 Identity = 79/313 (25.24%), Postives = 115/313 (36.74%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPR--KRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG---PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P P NG + + + C+ GY ++ C N + P C T C + P I + DF+ G V C GYE + + I C GN W + +C K CG P G + ++ YQS C + R CQ DG WSG C T C P G + + V S+ F+C+ G+ L GS R C + W G+ CI +C PP + V + ++G Y C+S L G + C +G +P
Sbjct: 2897 INCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVT--CTAPPPISNGLLEGR----DFEWGTSVSYSCSPGYELSFPA--ILTCVGNGTWSGEVPQCLPKFCGDPGTPAFG-SREGRSFIYQSEV--------SFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHV--DVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMP 3190 HSP 7 Score: 62.003 bits (149), Expect = 2.741e-9 Identity = 65/259 (25.10%), Postives = 92/259 (35.52%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKI------QCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
C + PP+ NG G V Y+C GY L P C N SG P+C + C P T + F +V C Y + I + +G W +C + + E+P R Y S+ F GFK+ QC + R CQAD WSG C C + P + +V+G+ + + C+ G+ L G S R C +G W G C
Sbjct: 2954 CKAVTCTAPPPIS--NGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPK--FCGD----PGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGT-WSGSQPRCIEPTRTTCENPGTPR--------YGSLNRTF---GFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVC 3192 HSP 8 Score: 58.151 bits (139), Expect = 4.264e-8 Identity = 51/206 (24.76%), Postives = 79/206 (38.35%), Query Frame = 3
Query: 345 CVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD-DFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
CV + G V + C P P G + +V ++C + Y G R CQ + SGS+P C + T P P + + NR FK G V CQ G+ + C + W +C SC + E P + + + +Y I C GF + ++ R C++DG W+G +C
Sbjct: 2999 CVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPR---YGSLNRTFGFKVGSMVAFQCQPGHL--LQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEH-------RVCRSDGTWTGKMPVC 3192
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Match: csmd3a (CUB and Sushi multiple domains 3a [Source:ZFIN;Acc:ZDB-GENE-050419-118]) HSP 1 Score: 109.768 bits (273), Expect = 4.214e-24 Identity = 97/337 (28.78%), Postives = 138/337 (40.95%), Query Frame = 3
Query: 657 VKIICQNGYEDPYKSHIIAKCNGNE-----WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI--CTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SWNFIP---RCVEAACSARPP-SMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
V+ C G+ K+ +A C E W C+ SCG P NG + +Y+ + A FCNDGF++ + CQADG WS I CT I C EL P NG+ +G T + F C G+ L GS +R+C G W G+ + C+ +CG P IV +V E + Y+C LIG +S C + N SG LP C I+ F ++D VT CN GY L C + W+ P R V P S++ S + + + ++ Y C+ GYY+
Sbjct: 2439 VRWACDRGFRLIGKN--MAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVL-AADYSAGTRATYFCNDGFRLS------SKEVTSTVCQADGTWSSHNKIPRCTVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIG-SSVRICQQDHNWSGQLPS--------CVSISCGHPGSPIYGRTVGDGFNLNDVVTF------FCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYL 2751 HSP 2 Score: 105.145 bits (261), Expect = 1.143e-22 Identity = 144/534 (26.97%), Postives = 203/534 (38.01%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYAL--KGPRKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG----PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCV---EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
+ C PV PVNG + G + Y C G+ L K CQA+ S P CT + C P P + + F G C +G+ + +C W C CG E NG+ + N+ Y+ + CN GF++ ++ R CQ D WSG C +I C P G +G +N + TF C +GY L G +C + W TC V NC P I +K+ Y T G Y C L G +S LTC V G+ KP P+CL +VD H + + D+ T G+ V +C L + AC NG W P C AC P + ++T S + + R+ C G+ + + I G W+ + PT C+P +C P TP NG R++ S + ++ Y C YRL G CL NG WS + P C I
Sbjct: 2477 VSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVIS--CGELPTPPNGK--KIGTQTTF--GATAIFTCNSGFI--LVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVI-GENFGYRDTVVYQCNPGFRLIGSS--------VRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFG-SSVLTCQPV----GYWDKPLPECL------EVDCG----HPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGAC-GDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAE---------RICFPNGTWSGRQPT--CKPVQCGNPGTPANG-----------RVSHVSGTTFSHSII-YSCVEGYRLSGSPTRQCLANGTWSGGE-PNCTLI 2953 HSP 3 Score: 88.1965 bits (217), Expect = 2.513e-17 Identity = 128/529 (24.20%), Postives = 187/529 (35.35%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG---RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTH-VRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS-ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
C P + VNG D V Y C G+ L G R CQ + SG P C + C P + ++ + D F + V C GY E P + A+C + +W P C +C P N + N+T+ ++ CN G+ + ++ CQ G W C + C P + V G T S ++C E L G R C G W GS C CG P A + A+ + C + TL G + C SG P CKP Q + + H T +H + C GY L+ C NG+W+ P C +C + P+ T ++ H+ Y C G+ ME S+ + G W+ +P+ CQ C+ PP NGE+ + + + V Y C Y L P + C NG WS ++P C
Sbjct: 2598 HCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSIS--CGH----PGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSE----AQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSS--------VLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERI-CFPNGTWSGRQPT--------CKPVQCG------NPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHN--VSYSCQPGFM-------MENGSSAIRTCTHNGTWSGSLPS--CQAVTCSPPPAVSNGEV-------EGSVFEWGVS------VSYRCMMGYELSFPAVLTCAGNGSWS-GEIPLC 3068 HSP 4 Score: 87.4261 bits (215), Expect = 3.990e-17 Identity = 104/446 (23.32%), Postives = 164/446 (36.77%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--TDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL---NSDILPACYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P+ G + D V + C GY L+GP + CQ++ + S P C + TD P IP + + +F G V C GY + S ++ W +C + CG P + + + +T+ S +C D+ R CQ +G+W G C+ C + P + ++ F C G+ L+GS R C G W G TC CG P +V++ TT Y C L G + C SG EP C L+ C V ++ + E + T G +V C G+ + +S I +NG+W+ +P C CS PP++ V + Y C GY ++
Sbjct: 2636 VRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTD-----PGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYL-FGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHA-VVTGDKFTFGSTV--------HYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPT-RQCLANGTWSGG----EPNCTLISCGDSGVPASGLRTGE-----------DFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSP-PPAVSNGEVEGSVFEWGVSVSYRCMMGYELSF 3049 HSP 5 Score: 83.5741 bits (205), Expect = 6.314e-16 Identity = 81/322 (25.16%), Postives = 122/322 (37.89%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANH-SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI---VRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLH-CK 1334
+QC P P NG +H S + Y+C GY L G R C AN SG EP CT + +P + + +DF G +V CQ G+ S I C N W C+ +C NG + +++ + C G+++ C +G WSG+ +C C + P G + F C Y L GS R C + W G+ CI C P F + + G+ ++ C++ L+G T+ TC + SG +P+C+ H CK
Sbjct: 2894 VQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTL---ISCGDSGVPASGLRTG---EDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEV--EGSVFEWGVSVSYRCMMGYELSFP--------AVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTT-RTCQQDLTWSG----SQPECIPHSCK 3194 HSP 6 Score: 82.8037 bits (203), Expect = 1.082e-15 Identity = 79/310 (25.48%), Postives = 120/310 (38.71%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRK--RYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEV-MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P +G VG V Y+C+ G+ ++ R C N SGS P C Q C P + +V + F+ G V C GYE + + + NG+ W + C K CG P R ++ +++ + C+ + + ++ R CQAD WSG C T C PE G + + V S F C+ G+ L GS R C ++ W GS CI +C P A V + + G Y C+ L G + C + +G +P
Sbjct: 2953 ISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSC--QAVTCSPPPAVSNGEVEGSV----FEWGVSVSYRCMMGYELSFPAVLTCAGNGS-WSGEIPLCLPKFCGDPGIPSRARRE-GQSFIFKAEVMFSCSAPYVLVGSS--------TRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVP 3246 HSP 7 Score: 62.3882 bits (150), Expect = 2.144e-9 Identity = 46/215 (21.40%), Postives = 82/215 (38.14%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
+ + C + G + + + C P P + +V ++C + Y L G R CQA+ SG++P C + T P P + ++ FK G VK +CQ G+ C + W +C SC + + P + + + ++ + C GF + ++ R C+ DG W+G +C A
Sbjct: 3047 LSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTP--EFGSLNSSLGFKVGSTVKFVCQTGHL--LLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEH-------RACRPDGSWTGKVPVCRA 3250
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Match: csmd2 (CUB and Sushi multiple domains 2 [Source:ZFIN;Acc:ZDB-GENE-030616-39]) HSP 1 Score: 108.227 bits (269), Expect = 1.588e-23 Identity = 115/446 (25.78%), Postives = 171/446 (38.34%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-CNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTY-QSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAK-VYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMP 1712
C P PV+G G V ++C+ GY LKG +R C AN G +PEC + P Q HD + C+ GY Y + ++ + C N W D +C +CG P NG + +++TY S++ Q C+ GF + D+ C D W+G +C AI+C NG+V+G S ++ C +GYQL + C GNW G C CG P K T+ + + C L+G G +P C+ VD ++ H+NN I G+ V C G+ L I C N +W+ + P C+ C+ P + SL + + Y C G+Y+A G E + D G+WT P
Sbjct: 2938 CGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKGSSERTCLANGSWVGIQPECHVVSCGNPGTPRNAMIQFHDG-----LVFSRSITYSCREGY---YSTGLLTRHCTVNGTWTGDMPECTVINCGDPGVPANGIRL-GSDFTYSHSVSFQ-CSPGFTMDA------DRASTLICTKDRTWNGTKPVCKAIVCAAPPSIPNGQVVGSDFQWGSSISYSCNQGYQLSLPTILTCQGSGNWSGERPQCFPVFCGDPGIPAQGKREDRGFTYLSSVSFSCYPPLILVGSAR-----RYCQYDGTWSGTQPSCIDPSHTSCVDPGTPLFGHQNNSQGYQI-------GSSVYYSCRKGHLLLGSISRTCLPNLTWSGMQPECIAHHCNQPELPAQADVGAIELPSLGYTLI--YTCQPGFYLA---GGSEHRTCRAD-----GSWTGKP 3345 HSP 2 Score: 99.7525 bits (247), Expect = 5.982e-21 Identity = 136/581 (23.41%), Postives = 204/581 (35.11%), Query Frame = 3
Query: 399 CQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYC----QANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPI----KCEKKSCGKLE----DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSW-NFIPRCVEAACSARPPSMKYSTVRFL------SLKHDSLARYYCHFGYY------IALRKDGM--ETLSTIFDIKCNKGNWTKMP----TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIK-------------------PIH----------NRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
C P PVNG + + +G + + C G+ L G C Q + + P C Q C +P V+ F G V C G+ + C ++ PI +C +C + D R +Y Y+++ + C+ G+ F +CQA+G W C I C +L P NG +G + F C GY L GS +R+C G W G+ C+ +CG P IV ++ E + Y+C LIG S C + SG P C P + + T F ++D VR CN GY L + C NG W N +PRC C+ P + VR + + Y C+ GYY ++ + DG +L + C++ MP G + + G+ ++G + R D P+H VV++ C P Y+LKG CL NG W Q P C +
Sbjct: 2450 CSSPDPPVNGSLHSQTGTKLGSTLRFNCDRGFNLIGQTTATCYRTPQGIYQWNAPVPLC--QVVSC----GMPIAPVNGTVIGQHFTLGSRVTFSCNPGFRLANTQPVSTLCQ-ESGRWSPIETRPRCVPVNCPDIGHSAVDHGRWRLIYGMQNKYEAMMMLTCDPGY--------FYKGQRVIRCQANGTWDYPEPRPSCEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGAEVQCLAGHCGTPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIG-VSVRICEQDHRWSGKTPV--------CIPITCGHPGTPANGVTQGTQFNLNDI------VRFACNPGYVLQGALKSQCQSNGQWSNALPRCKIVNCTD--PGHVENGVRQVLPSGPHRYSFQTAVSYNCNPGYYLLGSSILSCQGDGTWDRSLPKCLLVLCDR---PSMPPYAQISGDRRTVGSVIRFSCIGQRSIVGNTTRMCQLDGQWSGSLPHCSGDSAGLCGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKGSSERTCLANGSWVGIQ-PECHVV 2994 HSP 3 Score: 83.5741 bits (205), Expect = 6.387e-16 Identity = 140/588 (23.81%), Postives = 212/588 (36.05%), Query Frame = 3
Query: 228 KPECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMY----NNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLS-LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEI----YLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWS 1916
+P C + S ++ PNG TA C Y R + C+ + G + C P VNG V Y C G+ L G R C+ + R SG P C T C P T + + F + V+ C GY + + ++C N +W +C+ +C +NG + Y++Q+ CN G+ + ++ CQ DG W C +LC S P ++ G TV S+ F C + G+ R C +G W GS C + CG P V E T G+ + C+ L G +S TC + N S W+ +P+C V S N F HD + + C GY + C NG+W +P C C P + + +R S + + C G+ + + ST+ K N TK P C+ C PP+ NG++ + G S + Y C+ Y+L P I C +G+WS
Sbjct: 2632 RPSCEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGAEVQCLAGHCGTPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGKTPVCIPIT--CGH----PGTPANGVTQGTQFNLNDIVRFACNPGYV--LQGALKSQCQSNGQWSNALPRCKIVNCTDPGHVENGVRQVLPSGPHRYSFQTAVSYNCNPGYYLLGSS--------ILSCQGDGTWDRSLPKCLLVLCDRPSMPPYAQISGDRRTVGSVIRFSCIGQRSIVGNTTRMCQLDGQWSGSLPHCSGDSAGLCGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKG-SSERTC--LANGS-WV-GIQPEC-------HVVSCGNPGTPRNAMIQF--HDGLVFSRSITYSCREGYYSTGLLTRHCTVNGTWTGDMPECTVINCGD--PGVPANGIRLGSDFTYSHSVSFQCSPGFTMDADR-----ASTLICTKDRTWNGTK-PV--CKAIVCAAPPSIPNGQVVGSDFQWGSS-----------------ISYSCNQGYQLSLPTILTCQGSGNWS 3162
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Match: csmd3a (CUB and Sushi multiple domains 3a [Source:ZFIN;Acc:ZDB-GENE-050419-118]) HSP 1 Score: 93.5893 bits (231), Expect = 3.828e-19 Identity = 103/422 (24.41%), Postives = 160/422 (37.91%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG----EVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+ C P NG + G +TC SG+ L G R C + SG+E C C IP V+ ++F + V C G+ S I + + N W C SCG P GRT+ + + + FCN G+ ++ ++ QCQ+D +WS C + C + P N ++ T ++ ++ C GY L GS + C G WD C+ +CG P A V + T G+ Y+C LIGE++ +G +P C K H + ++F H + VR C+ G+ L C+ NG+W+ P C C P + + S V + H + Y C GY ++
Sbjct: 683 ISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCL--AGHC----GIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHN-WSGQLPSCVSISCGHPGSPIYGRTV-GDGFNLNDVVTFFCNKGYILEGPSEA--------QCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGEST-----RACQLNGQWGGSQPHCSGD-KRGACGDPGTPAHATREESSFQQHAK------VRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSII--YSCVEGYRLS 1074 HSP 2 Score: 92.8189 bits (229), Expect = 7.951e-19 Identity = 105/440 (23.86%), Postives = 163/440 (37.05%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQAN----LRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYK--SHIIAKCNGNEWKYDPI-KCEKKSCGKLE----DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SWNFIP---RCVEAACSARPP-SMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
G + + C P P +G + + V V + C G+ L G C+ L S P C Q C +P V+ D+ G C +G+ K + + + +G ++ I +C C + D R + + Y Y + CN G+ + C ++G WS + C I C EL P NG+ +G T + F C G+ L GS +R+C G W G+ + C+ +CG P IV +V E + Y+C LIG +S C + N SG LP C I+ F ++D VT CN GY L C + W+ P R V P S++ S + + + ++ Y C+ GYY+
Sbjct: 485 GFRITYVAMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPAC--QAVSC----GMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGY--------YRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIG-SSVRICQQDHNWSGQLPS--------CVSISCGHPGSPIYGRTVGDGFNLNDVVTF------FCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYL 895 HSP 3 Score: 88.5817 bits (218), Expect = 1.342e-17 Identity = 139/594 (23.40%), Postives = 205/594 (34.51%), Query Frame = 3
Query: 228 KPECHVKSLDNVKHLPNG---------CPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG---RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTH-VRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS-ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
+P C V S + PNG + T N + + C+ G + C P + VNG D V Y C G+ L G R CQ + SG P C + C P + ++ + D F + V C GY E P + A+C + +W P C +C P N + N+T+ ++ CN G+ + ++ CQ G W C + C P + V G T S ++C E L G R C G W GS C CG P A + A+ + C + TL G + C SG P CKP Q + + H T +H + C GY L+ C NG+W+ P C +C + P+ T ++ H+ Y C G+ ME S+ + G W+ +P+ CQ C+ PP NGE+ + + + V Y C Y L P + C NG WS ++P C
Sbjct: 677 RPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSIS--CGH----PGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSE----AQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSS--------VLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERI-CFPNGTWSGRQPT--------CKPVQCG------NPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHN--VSYSCQPGFM-------MENGSSAIRTCTHNGTWSGSLPS--CQAVTCSPPPAVSNGEV-------EGSVFEWGVS------VSYRCMMGYELSFPAVLTCAGNGSWS-GEIPLC 1212 HSP 4 Score: 83.9593 bits (206), Expect = 3.707e-16 Identity = 79/319 (24.76%), Postives = 120/319 (37.62%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANH-SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI---VRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLH 1328
+QC P P NG +H S + Y+C GY L G R C AN SG EP CT + +P + + +DF G +V CQ G+ S I C N W C+ +C NG + +++ + C G+++ C +G WSG+ +C C + P G + F C Y L GS R C + W G+ CI C P F + + G+ ++ C++ L+G T+ TC + SG +P+C+ H
Sbjct: 1038 VQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTL---ISCGDSGVPASGLRTG---EDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEV--EGSVFEWGVSVSYRCMMGYELSFPA--------VLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTT-RTCQQDLTWSG----SQPECIPH 1335 HSP 5 Score: 83.1889 bits (204), Expect = 6.695e-16 Identity = 79/310 (25.48%), Postives = 120/310 (38.71%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRK--RYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEV-MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P +G VG V Y+C+ G+ ++ R C N SGS P C Q C P + +V + F+ G V C GYE + + + NG+ W + C K CG P R ++ +++ + C+ + + ++ R CQAD WSG C T C PE G + + V S F C+ G+ L GS R C ++ W GS CI +C P A V + + G Y C+ L G + C + +G +P
Sbjct: 1097 ISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSC--QAVTCSPPPAVSNGEVEGSV----FEWGVSVSYRCMMGYELSFPAVLTCAGNGS-WSGEIPLCLPKFCGDPGIPSRAR-REGQSFIFKAEVMFSCSAPYVLVGSST--------RTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVP 1390 HSP 6 Score: 66.2402 bits (160), Expect = 1.127e-10 Identity = 132/558 (23.66%), Postives = 198/558 (35.48%), Query Frame = 3
Query: 399 CQPPVQPVNGH--ANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWK-------YDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI--------CTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPE-PKCLLHCKP----FQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGY-ELNSDILPACYNGSW---NFIPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIM--HDELPI 1967
CQPP N A +GD + Y C G+ L G C+ RL P P QV N F + +I GY D Y + + N K + + EK+ + + +G +Y+ QS+A+ + TT Q +WS D A+ C P++G V+ VNS+ + C G++L G ++ C R WD S C +CG P V V + G +A Y C L + T + D W + P+C + P F +D K I ++ +GT V CN GY L + NG+W N PRC +C PP+ K + + A + C+ G+ I + E L + G W+ T C C P NG++ +G++ R T V Y+C+P +RL G + +C H Q+P+C I H PI
Sbjct: 321 CQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPP--------------PVCQVQCPDNEVLF---DSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEF--DILEIFDGPNIYS-----QSLAVLSGDLSVPFNITTTGH---------QLFLRWSSDHGTNKKGFRITYVAMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGT--WSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSR---------YEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQ---TTFGATAIFTCNSGF-ILVGSTVRECLPS--------GLWSGTETH-CLAGHCGIPERIVNGQV--IGENFGYRDT-----------VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPI 808 HSP 7 Score: 63.1586 bits (152), Expect = 9.259e-10 Identity = 46/215 (21.40%), Postives = 82/215 (38.14%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
+ + C + G + + + C P P + +V ++C + Y L G R CQA+ SG++P C + T P P + ++ FK G VK +CQ G+ C + W +C SC + + P + + + ++ + C GF + ++ R C+ DG W+G +C A
Sbjct: 1191 LSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTP--EFGSLNSSLGFKVGSTVKFVCQTGHL--LLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEH-------RACRPDGSWTGKVPVCRA 1394
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Match: SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:100493788]) HSP 1 Score: 129.798 bits (325), Expect = 3.104e-30 Identity = 137/537 (25.51%), Postives = 206/537 (38.36%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDF------KNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-----RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
+ C P + NG N L G V Y C GY L G + +C N +G P C D D C N+N +G+ K + + GY + N W + CE +C K ++ +NG + T+ S A C G+ +Q C+A G WS + C + C + + G T ++I T+KCKEGY L G C+ G W C+ +C PP + +A G A Y C +++ L + + W+P P+ K + +C + H ++ N + G+ V KC G+ LN+ C G +IP +C+ C PPS+K V + S+ Y C GYYI K S G W+ ++P C P C PP +NG + +T L ++ V Y C+P Y+L G + VC LN HW PTC + ++ P
Sbjct: 1645 ISCGKPPRLENGFYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWNGISPSCLD-VDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLGKCGYTLIGNEETVCLAN-RSWSHALPTCESVTCSKPKEIENG-IFSLSGLTFNSTASYACKTGYSLQGPATLI--------CEASGNWSSEVPSCDLVSCGPPPLVRDADATGDNYTYSNIITYKCKEGYTLVGPDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQML----CNTEGNWVP-PDGKEIPNCIADFCERPSSVAHSILESVN---KAKFVSGSTVSFKCMEGFVLNTTARIECVRGG-QWIPSSLTIQCIPVRC-GEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLAS---------GEWSGRLPA--CHPGSCDDPPKLENGFV-----KSKTGL-------LYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPP 2137 HSP 2 Score: 100.138 bits (248), Expect = 5.711e-21 Identity = 131/571 (22.94%), Postives = 203/571 (35.55%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-------------------------------WNT---------------------------VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTN-FIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSP 1919
++C P P NG +++ +G V + CK GY L G K C AN + + P+C + P +H + ++ + C GY+ S + + +W + C SCG+ NG+ + N YT+ CN+G+++ R C +G WSG T C AI C + NGEV G WN+ N + C GY++HGS R+C G W GS TC+ C P P + ++ + T G KC+ L+G +S LTC S P HC KV N FI T +R C GY + C G W+ P C +C PPS+ + + S + +L Y C GY + +D + + + + D + G+ +P + L QS ++ + + N+ + C Y L GP + C+N G+W P
Sbjct: 2558 IECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCV------IISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQIS-KQWDGEEPICVPVSCGQPPMVINGKVI-GNEYTFSKTIEYVCNEGYRLYGEE--------IRTCLENGNWSGTTPSCLAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCLPCEC-PTPVVQNGIMSGDDFTCGHSVSIKCREGFKLLG-SSELTCQSAGKWSSGFP--------HC-------GKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQLLSC-GLPPSVLNAVLIADSYTYGNLF-YRCQDGY--VMHQD-VSSKTCLEDGSWSPGDIVCVPKK-------------------CLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGNWIP 3071 HSP 3 Score: 100.138 bits (248), Expect = 5.861e-21 Identity = 133/543 (24.49%), Postives = 205/543 (37.75%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-------TFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW--NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
+ C P + NG + S L Y CK+GY+L+GP C+A+ S P C DL P P ++ D++ + C+ GY I +G +W +C SC ++P N + ++++ + A +C+DG+ + N + C +G W + C A C S + +VN K +FKC EG+ L+ + +C R G W S+ T CI CG PP I V+ + G+ Y C + GE TC SG LP C P D + K+ ++++ + V CN GY+L + C N W P CV C +PP +KY +++ + + S ++C GY LS C K G W K T C P KC PP +N L K + P +V++ C + L+G + CL P C+ + P
Sbjct: 1772 VTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSLQGPATLICEASGNWSSEVPSC----DLVSCGP--PPLVRDADATGDNYTYSNIITYKCKEGYTLVGPDTINCSSSG-KWSEHIPQCMAVSC---DEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMV--------DNAQMLCNTEGNWVPPDGKEIPNCIADFCERPS----SVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKK-RTCLASGEWSGRLPA--------CHPGSCDDPPKLENGFVKSKTGLLYE-----SKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCE-KPPPVKYGSMKGENFEVGSKVEFFCEDGY----------ELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYEN------------HLVLKEV-PNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPP 2254 HSP 4 Score: 98.2117 bits (243), Expect = 2.732e-20 Identity = 126/522 (24.14%), Postives = 196/522 (37.55%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAK-VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C GY +KG +KR C A+ SG P C + C P + V ++ V C GY+ + + + N + + P C +C K K G +M N+ S FC DG+++ + CQ +G+W T C C + EN V+ I F CKEG+ L GS + KC W+ S C + C PPE+ + + ++ + G+ +Y C L GE S +TC N SG W P +C P + + ++ + +T + C GYEL + C +G W P C CS + + F SL + Y C+ G+ R +G L+ + G W P C+ C P NG + S + ++ + C P ++L G + C WS P C
Sbjct: 2011 IPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGS--CDDPPKLENGFVK---SKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPPPVKYG-SMKGENFEVGSKVEFFCEDGYELS--------GDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGE-SVITC----NASGMWSPD-----FPNCSPIECPQPEEILN------GIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCS-KAKEILNGKFSFQSLNYGQTITYTCNRGF----RLEGQNVLTCL-----ETGEWNSNPPI-CKEITCDPPQGIDNGFVEGADYS-------------YGAMIIFSCMPGFQLVGLAMQTCEESGWS-SSTPVC 2477 HSP 5 Score: 95.5153 bits (236), Expect = 1.762e-19 Identity = 135/561 (24.06%), Postives = 206/561 (36.72%), Query Frame = 3
Query: 342 LCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD--DFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGK------------------LEDPKNGRTMYN-NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKC-NKGNW-TKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHW--SPPQMPTCE 1940
+C D Y G + ++C + +NG + L G + YTC G+ L+G C + + P C + T Q DN + D+ G + C G++ + C + W C CG L D + +++ + Y Y + I CN+G++I + C+ DG W+G C I C + PENG + NT+ S F+CK GY+L+GS C W+ C++ +C P +I+ T+ + YKC + G S TC G EP C+ P + I N K ++ +E T + CN GY L + + C NG+W+ P C+ C K ST ++ + + C G I R + + + C N G W + P C+P C P NG L + K +N + Y C P Y + G CL NG W SPP CE
Sbjct: 2348 ICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQNVLTCLETGEWNSNPPICKEIT--------CDPPQGIDNGFVEGADYSYGAMIIFSCMPGFQ--LVGLAMQTCEESGWSSSTPVCLHTDCGLPPHIDFGQYTIVTFEEKILTDDELKHSIFGLSEYLYGTNVIYSCNNGYEILGMS--------VLTCKEDGTWNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYG-LSQRTCQISKQWDG----EEPICV----PVSCGQPPMVI--NGK----VIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC-------KIST----TVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPL--CEPIHCEPPEDISNG-----------YLNSSNFK--YNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCLPCE 2849 HSP 6 Score: 93.2041 bits (230), Expect = 8.690e-19 Identity = 146/600 (24.33%), Postives = 214/600 (35.67%), Query Frame = 3
Query: 396 QCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQANLR-LSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-----------------------------DP--YKSHIIAKCNGNE---------------------------WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ-VDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSW-NFIPRCVEAACSARPPSM---KYSTVRFL-------SLKHDSLAR----------YYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
C P + NG + + LL +V Y C GY L G R CQ N S S P C T C P + Y + ++F+ G V+ C++GYE DP Y++H++ K NE W C+ C + G + + + S C DGF ++ + C A G WS D C+ I CP+ NG V T S + CK GY+L G+ C +G W G C C EI+ K ++++ +G Y C L G+ + LTC E W P + C P Q +D+ F+ + ++G + C G++L + C W + P C+ C PP + +Y+ V F LKH Y C+ GY I GM L+ D G W C P +C+ P P+NG ++ TD +I V +EC P Y L G ++CL N W+ ++P C I
Sbjct: 2072 SCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLT--CEKPPPVKYGSMKG----ENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGES--------VITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQ-NVLTCLETGE---WNSNPPICKEITCDPPQGIDNG------------FVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEESGWSSSTPVCLHTDC-GLPPHIDFGQYTIVTFEEKILTDDELKHSIFGLSEYLYGTNVIYSCNNGYEIL----GMSVLTCKED-----GTWNGS-APACAPIECSIPTDPENGVMH---------YTDNTI----GSSVHFECKPGYELNGSDKSICLANKQWN-NEIPKCVII 2616 HSP 7 Score: 93.2041 bits (230), Expect = 9.468e-19 Identity = 77/286 (26.92%), Postives = 110/286 (38.46%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCP-ELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG 1247
+ C P P +G + L D V Y C G+ L GP +R C + + P C C S PYI N ++ C GY H+ NG W +C++ C + P+NG Y N ++ Q C +G+ + + ED +C +G WS IC A CP PEN + V + KC++GYQL G + C + W +N C +CGPP I + G Y C S L+G
Sbjct: 3081 VSCGEPAAPEHGIVLGTRYLFKDSVLYHCNHGFELNGPSRRICHIDKQWIPPPPTCV----TCDSLPYIENAVYTSTGNTYT----HNITFTCNFGYHLVGPPHVRCLVNGT-WSKPLPQCKETRCEVPQQPENGHAEYENVTVGSTVRYQ-CQNGYTL-----EGED---LAECTTNGTWSHPVPICKANPCPVPFVIPENAILTETDFYVGQKVSIKCRKGYQLQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYMLLG 3348 HSP 8 Score: 88.9669 bits (219), Expect = 1.820e-17 Identity = 125/521 (23.99%), Postives = 196/521 (37.62%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS--NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRK-CTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+ C+PP NG+ N S + + Y C GY + G R C AN SGS P C P T V N + DDF G V I C+ G++ S + + G +W C K CG P N + + AI++ C G+ +Q ++ C +G WS C + C L P V+ + ++C++GY +H K C +G+W + C+ + C ++ K CK TL G ++ TC N W+P+ C P H T ++ D V + CN G+ELN C+ P C + P ++ + + + C+FGY++ G + + + G W+K P C+ +C P P+NG ++ +T S V+Y+C Y L+G +A C NG WS P +P C+
Sbjct: 2790 IHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCL---------PCECPTPVVQNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAG-KWSSGFPHCGKVPCGP--PPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELL--------CTKEGVWSKPYPNCQLLSC-GLPPSVLNAVLIADSYTYGNLFYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTS-TC---MNDGNWIPEVNNNI---CTPVSCGEPAAPEHGIVLGTRYLFKDSVLY------HCNHGFELNGPSRRICHIDKQWIPPPPTCVTCDSLP-YIENAVYTSTGNTYTHNITFTCNFGYHLV----GPPHVRCLVN-----GTWSK-PLPQCKETRCEVPQQPENG------HAEYENVTVGS-------TVRYQCQNGYTLEGEDLAECTTNGTWSHP-VPICK 3251 HSP 9 Score: 78.9518 bits (193), Expect = 2.118e-14 Identity = 125/531 (23.54%), Postives = 191/531 (35.97%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-----CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNS-----IKTF-----KC--KEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA-------------LRKDGMETLSTIFDI-------------KCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIH-------------------NRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELP 1964
++ C P + T H ++ + D K G + + C G++ I+ K N EW CE+ SCGK +NG YN + + + QC + + R C +G W+G + C + E+ + E NT S I + KC K GY L G+ C +W + TC C P EI + T + A Y CK+ +L G + L C N S +P + L+ C P + + + + T D T+ + KC GY L D + +G W+ IP+C+ +C PP++ Y++ A YYC GY + + DG E + I D NK + T + + T E GQ + LT + I P+ VV Y C Y +KG K CL +G WS ++P C D+ P
Sbjct: 1581 KSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQ------IVGKPERQCLNLGEWDQPLPHCERISCGKPPRLENG--FYNAEDLFAGSTVTY-------QCNIGYYLLGDSRMFCTDNGSWNGISPSCLDVDECEIG-SDCDEHASCMNTNGSYICTCIPPYHGDGKKCLGKCGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSLQGPAT-LICEASGNWSSEVPSCD---LVSCGPPPL------VRDADAT-----GDNYTYSNIITYKCKEGYTLVGPDTINCSSSGKWSEHIPQCMAVSCD-EPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCI-PVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWS-GRLPACHPGSCDDPP 2077 HSP 10 Score: 72.7886 bits (177), Expect = 2.027e-12 Identity = 55/187 (29.41%), Postives = 83/187 (44.39%), Query Frame = 3
Query: 390 DLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG 941
+ +C+ P QP NGHA + + VG V Y C++GY L+G C N S P C + + C IP + + DF G+ V I C+ GY+ + + CN +E W +KCEK SCG +NG R MY + + + C G+ + + R C +G W+
Sbjct: 3194 ETRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPIC--KANPCPVPFVIPENAILTET---DFYVGQKVSIKCRKGYQ--LQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMY---HQFGDVVTYSCYSGYMLL--------GSFRSVCLENGTWTA 3362 HSP 11 Score: 59.3066 bits (142), Expect = 2.782e-8 Identity = 37/114 (32.46%), Postives = 56/114 (49.12%), Query Frame = 3
Query: 942 DTAICTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCG 1271
+ ++C + CPEL PPENG V + N ++ +CK GY L GS++R C G W GS++TC VR C + ++ + T++G C L G + L G
Sbjct: 342 EGSVCKVVHCPELRPPENGYFVQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSSDTSYGTMCIAYCNDGYVLEGSSKLLCLG 455 HSP 12 Score: 53.9138 bits (128), Expect = 1.063e-6 Identity = 89/362 (24.59%), Postives = 124/362 (34.25%), Query Frame = 3
Query: 453 VGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQ--TDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNG-RTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH-GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEV-THGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRC 1517
+ + CK GY L GP C + PE + T + P P + + R FK + V C +G+E S I + +W P C +C L +N T N YT+ I F CN G+ + +C +G WS C C PENG TV S ++C+ GY L G L +CT G W C C P I + E + G + KC+ L G+ + +TC + W V K+ + N I+ G V C GY L C NG+W P C
Sbjct: 3041 INKTITIVCKEGYTLTGPSTSTCMNDGNWI---PEVNNNICTPVSCGEPAAPEHGIVLGT-RYLFK--DSVLYHCNHGFELNGPSRRICHID-KQWIPPPPTC--VTCDSLPYIENAVYTSTGNTYTHN---ITFTCNFGYHLVGPP--------HVRCLVNGTWSKPLPQCKETRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPICKANPCPVPFVIPENAILTETDFYVGQKVSIKCRKGYQLQGQ-AVITCNADET---WTDA------------NVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYMLLGSFRSVCLENGTWTAPPSC 3366
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Match: SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:100493788]) HSP 1 Score: 112.079 bits (279), Expect = 1.248e-24 Identity = 136/559 (24.33%), Postives = 210/559 (37.57%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYE-LNSDILPACYNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEI------------------YLLGQ--SDRTRLTDKSIKP------------------IHNRVVKYE--------CHPLYRLKGPKIAVCLN-GHWSP 1919
++C P P NG +++ +G V + CK GY L G K C AN + + P+C + P +H + ++ + C GY+ S + + +W + C SCG+ NG+ + N YT+ CN+G+++ R C +G WSG T C AI C + NGEV G V ++C GY++ G+ C +G W+ + C +C PP +I + + Y C + G ++ + W P P CL P + + V N IM D+ T G V KC G++ L S L G W+ P C + C PPS+ + + S + RY C GY + + + + T +G W+K P CQ C PP+ N + Y++ Q S +T L D S P I N +Y+ C Y L GP + C+N G+W P
Sbjct: 2554 IECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCV------IISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQIS-KQWDGEEPICVPVSCGQPPMVINGKVI-GNEYTFSKTIEYVCNEGYRLYGEE--------IRTCLENGNWSGTTPSCLAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTR----QCLANGAWSGSP-PTCL----PCECPTPVV--------QNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGP-PPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCT---------KEGVWSK-PYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGNWIP 3068 HSP 2 Score: 105.916 bits (263), Expect = 1.036e-22 Identity = 99/376 (26.33%), Postives = 148/376 (39.36%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILP-ACY-NGSWN 1502
+ + C P +NG + +EY C GY L G R C N SG+ P C T I T + + G+++ C +GY+ + N W + CE C ED NG + ++N+ Y C G+++ ++ RQC A+G WSG C CP +NG + G T + KC+EG++L GS C G W C CGPPP I A + ++T Y C + + G++ L K G KP P C LL C P V +A ++ D T+G+ +C GY ++ D+ C +GSW+
Sbjct: 2668 VPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC------KISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCL-NDGTWNSNAPLCEPIHCEPPEDISNGY-LNSSNFKYNEYIHYVCFPGYEMHGSS--------TRQCLANGAWSGSPPTCLPCECP-TPVVQNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLC-----TKEGVWSKPYPNCQLLSCGLPPSVLNA------------VLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWS 3009 HSP 3 Score: 98.5969 bits (244), Expect = 1.867e-20 Identity = 126/522 (24.14%), Postives = 196/522 (37.55%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAK-VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C GY +KG +KR C A+ SG P C + C P + V ++ V C GY+ + + + N + + P C +C K K G +M N+ S FC DG+++ + CQ +G+W T C C + EN V+ I F CKEG+ L GS + KC W+ S C + C PPE+ + + ++ + G+ +Y C L GE S +TC N SG W P +C P + + ++ + +T + C GYEL + C +G W P C CS + + F SL + Y C+ G+ R +G L+ + G W P C+ C P NG + S + ++ + C P ++L G + C WS P C
Sbjct: 1982 IPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGS--CDDPPKLENGFVK---SKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPPPVKYG-SMKGENFEVGSKVEFFCEDGYELS--------GDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGE-SVITC----NASGMWSPD-----FPNCSPIECPQPEEILN------GIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCS-KAKEILNGKFSFQSLNYGQTITYTCNRGF----RLEGQNVLTCL-----ETGEWNSNPPI-CKEITCDPPQGIDNGFVEGADYS-------------YGAMIIFSCMPGFQLVGLAMQTCEESGWS-SSTPVC 2448 HSP 4 Score: 94.3597 bits (233), Expect = 4.219e-19 Identity = 125/525 (23.81%), Postives = 200/525 (38.10%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPR-----CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+ + C+ NG + VG ++ Y C GY ++G K C + + + P LC P + + N +FK E + +C GYE S NG W P C C +NG ++ S++I+ C +GFK+ +++ CQ+ GKWS C + C N + G +T + C GY + G CT+EG W C + +CG PP ++ A + ++ T+G+ A Y+C+ + + S TC E W P + C P + I N T + ++ +T C GY L C N N+IP C +C P + ++ V Y+C+ G+ + +G D + W P C +C P P+N G ++ +T S V+Y+C Y L+G +A C NG WS P +P C+
Sbjct: 2726 LAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAP-------LCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANG-AWSGSPPTCLPCEC-PTPVVQNGIMSGDDFTCGHSVSIK-CREGFKLLGSSE--------LTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLE---DGSWSPGD-----IVCVPKKCLLQSTLIQIKNDETEYDINKTIT------IVCKEGYTLTGPSTSTCMNDG-NWIPEVNNNICTPVSC-GEPAAPEHGIVLGTRYLFKDSVLYHCNHGFEL----NGPSRRICHIDKQ-----WIPPPPT-CVKTRCEVPQQPEN------GHAEYENVTVGS-------TVRYQCQNGYTLEGEDLAECTTNGTWSHP-VPICK 3192 HSP 5 Score: 93.5893 bits (231), Expect = 6.938e-19 Identity = 104/447 (23.27%), Postives = 157/447 (35.12%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPT 1715
+ C PP N N S D + Y C +GY ++G + C S P C Q C +P + ++ D + G CQ+GY W I C K C L KN T Y+ N T + C +G+ + + C DG W + ICT + C E + PE+G V+G + C G++L+G R C + W TC+ C P + YE T G+ Y+C++ TL GE E W P P C + P I EN + + G V KC GY+L + C + +W E P +++ +R + + + Y C+ GY + L + + G WT P+
Sbjct: 2901 VPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNC--QLLSCG----LPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIV----CKEGYTLTGPS--------TSTCMNDGNWIPEVNNNICTPVSCGEPAAPEHGIVLGTRYLFKDSVLYHCNHGFELNGPSRRICHIDKQWIPPPPTCVKTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGE----DLAECTTNGTW-SHPVPICKANPCP-----VPFVIPEN----AILTETDFYVGQKVSIKCRKGYQLQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYML---------LGSFRSVCLENGTWTAPPS 3306 HSP 6 Score: 92.4337 bits (228), Expect = 1.752e-18 Identity = 134/529 (25.33%), Postives = 199/529 (37.62%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKC-NKGNW-TKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHW--SPPQMPTCE 1940
+C EI C PP NG + G + ++C G+ L G + C+ + S S P C TD C P+I + Q + + KI+ +D K I N I + L+ + + Y Y + I CN+G++I + C+ DG W+G C I C + PENG + NT+ S F+CK GY+L+GS C W+ C++ +C P +I+ T+ + YKC + G S TC G EP C+ P + I N K ++ +E T + CN GY L + + C NG+W+ P C+ C K ST ++ + + C G I R + + + C N G W + P C+P C P NG L + K +N + Y C P Y + G CL NG W SPP CE
Sbjct: 2390 ICKEI--TCDPPQGIDNGFVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEES-GWSSSTPVCL-HTD-CGLPPHIDFGQYTIVTFEE--------KIL----TDDELKHSIFGVSN-------IILSPTTTSNTLKTENHSENSQLSEYLYGTNVIYSCNNGYEILGMS--------VLTCKEDGTWNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYG-LSQRTCQISKQWDG----EEPICV----PVSCGQPPMVI--NGK----VIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC-------KIST----TVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPL--CEPIHCEPPEDISNG-----------YLNSSNFK--YNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCLPCE 2845 HSP 7 Score: 85.5001 bits (210), Expect = 2.345e-16 Identity = 106/464 (22.84%), Postives = 162/464 (34.91%), Query Frame = 3
Query: 396 QCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQANLR-LSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-----------------------------DP--YKSHIIAKCNGNE---------------------------WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ-VDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA 1601
C P + NG + + LL +V Y C GY L G R CQ N S S P C T C P + Y + ++F+ G V+ C++GYE DP Y++H++ K NE W C+ C + G + + + S C DGF ++ + C A G WS D C+ I CP+ NG V T S + CK GY+L G+ C +G W G C C EI+ K ++++ +G Y C L G+ + LTC E W P + C P Q +D+ F+ + ++G + C G++L + C W + P C+ C PP + + ++ + L
Sbjct: 2043 SCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLT--CEKPPPVKYGSMKG----ENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGES--------VITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQ-NVLTCLETGE---WNSNPPICKEITCDPPQGIDNG------------FVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEESGWSSSTPVCLHTDC-GLPPHIDFGQYTIVTFEEKILT 2475 HSP 8 Score: 82.8037 bits (203), Expect = 1.591e-15 Identity = 131/572 (22.90%), Postives = 213/572 (37.24%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEP------ECTDQTDLCFS----APYIPYTQVHDNSNRDDFKNG----------EDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-------TFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW--NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
G C+E ++C+ P + NG+ + + VG Q+ ++C GY L G K C + + P ++ +C + + +P + S + +NG C+ GY C+ + +W +C SC ++P N + ++++ + A +C+DG+ + N + C +G W + C A C S + +VN K +FKC EG+ L+ + +C R G W S+ T CI CG PP I V+ + G+ Y C + GE TC SG LP C P D + K+ ++++ + V CN GY+L + C N W P CV C +PP +KY +++ + + S ++C GY LS C K G W K T C P KC PP +N L K + P +V++ C + L+G + CL P C+ + P
Sbjct: 1708 GKKCLE-PVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPCNEGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVSC---DEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMV--------DNAQMLCNTEGNWVPPDGKEIPNCIADFCERPS----SVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKK-RTCLASGEWSGRLPA--------CHPGSCDDPPKLENGFVKSKTGLLYE-----SKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCE-KPPPVKYGSMKGENFEVGSKVEFFCEDGY----------ELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYEN------------HLVLKEV-PNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPP 2225 HSP 9 Score: 82.4185 bits (202), Expect = 1.871e-15 Identity = 131/541 (24.21%), Postives = 201/541 (37.15%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYA--LKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIK--------CEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN--FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIH-NRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
+ C P + NG + S L Y CK+GY+ L GP C ++ + S P+C + C P + Y H S+ F G+ C +GY + ++ GN D + CE+ S LE + + + +++ C +GF + T R +C G+W S T C + C E +NG V G + S+ + C +GY + G R C G W G C +C PP++ V + + ++ Y C L+G + W + P C LL C KP V + K NF + G+ V C GYEL+ D+ C NG W+ P C+ + C PP + V + R+ C G+ + +G L + + N P C+ C+ PP GE S+ ++ VKY C + LKG + C +G WS P P C I
Sbjct: 1799 VTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVS--CDEPPNVDYASSH--SSHRLF--GDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFK------CMEGFVLNTTA--------RIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRV----CQLNRHWYSESPPTCVLLTCEKPPPVKYGSM------KGENFEV------GSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQ-DPPLYENHLVLKEVPNEVGIVRFSCKEGHVL----EGSSVLKCLPSQQWND----SFPL--CKLVFCSSPPELAYGEPI-------------SVPSLYFGSTVKYTCVDGFLLKGESVITCNASGMWS-PDFPNCSPI 2278 HSP 10 Score: 73.1738 bits (178), Expect = 1.333e-12 Identity = 55/188 (29.26%), Postives = 83/188 (44.15%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG 941
+ +C+ P QP NGHA + + VG V Y C++GY L+G C N S P C + + C IP + + DF G+ V I C+ GY+ + + CN +E W +KCEK SCG +NG R MY + + + C G+ + + R C +G W+
Sbjct: 3134 VKTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPIC--KANPCPVPFVIPENAILTET---DFYVGQKVSIKCRKGYQ--LQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMY---HQFGDVVTYSCYSGYMLL--------GSFRSVCLENGTWTA 3303 HSP 11 Score: 71.633 bits (174), Expect = 4.068e-12 Identity = 134/594 (22.56%), Postives = 199/594 (33.50%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-----CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGF------KIQCT---------------------TDQFEDKNCRRQ-----CQADGKWSGDTAICTA-ILCPELSPPENGEVMGVWNTVNSIKTFKC--------------------------KEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCK---------------------------------------------SRSTLIGETSFLTCGE----VDN-------KSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-----RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++ C P + T H ++ + D K G + + C G++ I+ K N EW CE+ SCGK +NG YN + + + CN G+ ++ CT +D E +C C + GD C + C + ENG G V S F C EGY L G+ C +W + TC C P EI + T + A Y CK S L G+T++ C + VDN + W+P P+ K + +C + H ++ N + G+ V KC G+ LN+ C G +IP +C+ C PPS+K V + S+ Y C GYYI K S G W+ ++P C P C PP +NG + +T L ++ V Y C+P Y+L G + VC LN HW PTC + ++ P
Sbjct: 1552 KSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQ------IVGKPERQCLNLGEWDQPLPHCERISCGKPPRLENG--FYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWNGISPSCLDVDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPCNEGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQMLCNTEGNWVP-PDGKEIPNCIADFCERPSSVAHSILESVN---KAKFVSGSTVSFKCMEGFVLNTTARIECVRGG-QWIPSSLTIQCIPVRC-GEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLAS---------GEWSGRLPA--CHPGSCDDPPKLENGFV-----KSKTGL-------LYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPP 2108 HSP 12 Score: 64.6994 bits (156), Expect = 5.382e-10 Identity = 55/194 (28.35%), Postives = 84/194 (43.30%), Query Frame = 3
Query: 942 DTAICTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNS--DILPACYNGSWN 1502
+ ++C + CPEL PPENG V + N ++ +CK GY L GS++R C G W GS++TC VR C + ++ + T++G C L G + L G S W K P+C +HC F + + N + +G CN G+ L+ D + NG W+
Sbjct: 346 EGSVCKVVHCPELRPPENGYFVQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSSDTSYGTMCIAYCNDGYVLEGSSKLLCLG----SSQWDSK-VPQCKEMHCPVFHKPNGVLSSPSN------CGQEPAKYGYSCHVGCNKGFMLSGVKDKIKCVANGKWS 528
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Match: SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:100493788]) HSP 1 Score: 111.694 bits (278), Expect = 1.632e-24 Identity = 136/559 (24.33%), Postives = 210/559 (37.57%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYE-LNSDILPACYNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEI------------------YLLGQ--SDRTRLTDKSIKP------------------IHNRVVKYE--------CHPLYRLKGPKIAVCLN-GHWSP 1919
++C P P NG +++ +G V + CK GY L G K C AN + + P+C + P +H + ++ + C GY+ S + + +W + C SCG+ NG+ + N YT+ CN+G+++ R C +G WSG T C AI C + NGEV G V ++C GY++ G+ C +G W+ + C +C PP +I + + Y C + G ++ + W P P CL P + + V N IM D+ T G V KC G++ L S L G W+ P C + C PPS+ + + S + RY C GY + + + + T +G W+K P CQ C PP+ N + Y++ Q S +T L D S P I N +Y+ C Y L GP + C+N G+W P
Sbjct: 2544 IECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCV------IISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQIS-KQWDGEEPICVPVSCGQPPMVINGKVI-GNEYTFSKTIEYVCNEGYRLYGEE--------IRTCLENGNWSGTTPSCLAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTR----QCLANGAWSGSP-PTCL----PCECPTPVV--------QNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGP-PPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCT---------KEGVWSK-PYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGNWIP 3058 HSP 2 Score: 105.531 bits (262), Expect = 1.425e-22 Identity = 99/376 (26.33%), Postives = 148/376 (39.36%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILP-ACY-NGSWN 1502
+ + C P +NG + +EY C GY L G R C N SG+ P C T I T + + G+++ C +GY+ + N W + CE C ED NG + ++N+ Y C G+++ ++ RQC A+G WSG C CP +NG + G T + KC+EG++L GS C G W C CGPPP I A + ++T Y C + + G++ L K G KP P C LL C P V +A ++ D T+G+ +C GY ++ D+ C +GSW+
Sbjct: 2658 VPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC------KISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCL-NDGTWNSNAPLCEPIHCEPPEDISNGY-LNSSNFKYNEYIHYVCFPGYEMHGSS--------TRQCLANGAWSGSPPTCLPCECP-TPVVQNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLC-----TKEGVWSKPYPNCQLLSCGLPPSVLNA------------VLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWS 2999 HSP 3 Score: 103.219 bits (256), Expect = 7.464e-22 Identity = 114/460 (24.78%), Postives = 168/460 (36.52%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQV-----------------------------------------HDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYN-GSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
+C EI C PP NG + G + ++C G+ L G + C+ + S S P C TD C P+I + Q +NS ++ G +V C NGYE S + K +G W C C DP+NG Y +N S+ + C G+++ + + C A+ +W+ + C I C + +G T S+ +KC +GYQ++G R C WDG C+ +CG PP ++ KV T EY C L GE TC E N SG P CL + K+ NN + E G + +CN GY++ C N G+WN P C C P + + + K++ Y C GY
Sbjct: 2380 ICKEI--TCDPPQGIDNGFVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEES-GWSSSTPVCL-HTD-CGLPPHIDFGQYTIVTFEEKILTDDELKHSIFGVSNIILSPTTTSNTLKTENHSENSQLSEYLYGTNVIYSCNNGYEILGMSVLTCKEDGT-WNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFE-CKPGYELNGSD--------KSICLANKQWNNEIPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQISKQWDGEEPICVPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGE-EIRTCLENGNWSG----TTPSCL-------AITCKISTTVNNGE---VTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEP-PEDISNGYLNSSNFKYNEYIHYVCFPGY 2808 HSP 4 Score: 101.679 bits (252), Expect = 2.229e-21 Identity = 136/526 (25.86%), Postives = 211/526 (40.11%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN---LRLSGSE-PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEW--KYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKT-FKCKEGYQLHGSHLRKCTREGNW-DGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSWN-FIPRCVEAACSARPPSMKYST-VRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW 1913
CM + P V + H++H L GD Y C GY++ + C + G E P C D C + ++ + ++ N+ F +G V C G+ + I +C G +W I+C CG+ KNG + NY++ S+ C+ G+ I+ +R C A G+WSG C C + ENG V + K + C GY+L GS++R C +W S TC++ C PP + + + E G++ E+ C+ L G+ S+ TC K+G W K P C+ P + +Y EN+ ++ + VR C G+ L S +L + WN P C CS+ PP + Y + SL S +Y C G+ L+ + + I CN C P +C +P NG + + G LT S Y C P Y L G +C +G+W
Sbjct: 1846 CMAVSCDEPPNVDYASSHSSHR--LFGDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCI--ADFCERPSSVAHS-ILESVNKAKFVSGSTVSFKCMEGFVLNTTARI--ECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGY-VSGTNYSFGSVVAYSCDKGYYIKGEK--------KRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPPPVKYGSMKGENFEVGSKVEFFCEDGYELSGDLSW-TC----QKNGEWDKKQTPTCM----PSKCQDPPLY--ENH----LVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSS-PPELAYGEPISVPSLYFGSTVKYTCVDGFL--LKGESV--------ITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQG------LTFLS-------AALYTCKPGYELIGNSTLICGADGYW 2316 HSP 5 Score: 92.8189 bits (229), Expect = 1.102e-18 Identity = 127/541 (23.48%), Postives = 191/541 (35.30%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-----CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG---------------------------DTAICTAI--------------LCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWD--------GSNST--------------CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-----RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++ C P + T H ++ + D K G + + C G++ I+ K N EW CE+ SCGK +NG YN + + + QC + + R C +G W+G + ICT I C + ENG G V S F C EGY L G C G WD G ++ C+ +C PP + +A G A Y C +++ L + + W+P P+ K + +C + H ++ N + G+ V KC G+ LN+ C G +IP +C+ C PPS+K V + S+ Y C GYYI K S G W+ ++P C P C PP +NG + +T L ++ V Y C+P Y+L G + VC LN HW PTC + ++ P
Sbjct: 1606 KSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQ------IVGKPERQCLNLGEWDQPLPHCERISCGKPPRLENG--FYNAEDLFAGSTVTY-------QCNIGYYLLGDSRMFCTDNGSWNGISPSCLDVDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQML----CNTEGNWVP-PDGKEIPNCIADFCERPSSVAHSILESVN---KAKFVSGSTVSFKCMEGFVLNTTARIECVRGG-QWIPSSLTIQCIPVRC-GEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLAS---------GEWSGRLPA--CHPGSCDDPPKLENGFV-----KSKTGL-------LYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPP 2098 HSP 6 Score: 92.4337 bits (228), Expect = 1.751e-18 Identity = 120/529 (22.68%), Postives = 195/529 (36.86%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPR-----CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGM----ETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+ + C+ NG + VG ++ Y C GY ++G K C + + + P LC P + + N +FK E + +C GYE S NG W P C C +NG ++ S++I+ C +GFK+ +++ CQ+ GKWS C + C N + G +T + C GY + G CT+EG W C + +CG PP ++ A + ++ T+G+ A Y+C+ + + S TC E W P + C P + I N T + ++ +T C GY L C N N+IP C +C P + ++ V Y C+ G+ + + + ST+ K + + P G ++ +T S V+Y+C Y L+G +A C NG WS P +P C+
Sbjct: 2716 LAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAP-------LCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANG-AWSGSPPTCLPCEC-PTPVVQNGIMSGDDFTCGHSVSIK-CREGFKLLGSSE--------LTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLE---DGSWSPGD-----IVCVPKKCLLQSTLIQIKNDETEYDINKTIT------IVCKEGYTLTGPSTSTCMNDG-NWIPEVNNNICTPVSC-GEPAAPEHGIVLGTRYLFKDSLHYSCNHGFELNGPSRRICHIDKHQSTVGKCKKTRCEVPQQPEN---------------------GHAEYENVTVGS-------TVRYQCQNGYTLEGEDLAECTTNGTWSHP-VPICK 3181 HSP 7 Score: 85.1149 bits (209), Expect = 2.781e-16 Identity = 106/464 (22.84%), Postives = 162/464 (34.91%), Query Frame = 3
Query: 396 QCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQANLR-LSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-----------------------------DP--YKSHIIAKCNGNE---------------------------WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ-VDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA 1601
C P + NG + + LL +V Y C GY L G R CQ N S S P C T C P + Y + ++F+ G V+ C++GYE DP Y++H++ K NE W C+ C + G + + + S C DGF ++ + C A G WS D C+ I CP+ NG V T S + CK GY+L G+ C +G W G C C EI+ K ++++ +G Y C L G+ + LTC E W P + C P Q +D+ F+ + ++G + C G++L + C W + P C+ C PP + + ++ + L
Sbjct: 2033 SCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLT--CEKPPPVKYGSMKG----ENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGES--------VITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQ-NVLTCLETGE---WNSNPPICKEITCDPPQGIDNG------------FVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEESGWSSSTPVCLHTDC-GLPPHIDFGQYTIVTFEEKILT 2465 HSP 8 Score: 83.9593 bits (206), Expect = 6.106e-16 Identity = 138/600 (23.00%), Postives = 207/600 (34.50%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLC--------------FSAPYI----------------------PYTQVHDNSNRDDFKNGEDVKIICQNGYED------------------PYK---SHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-------TFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW--NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
+ C P + NG N L G V Y C GY L G + +C N +G P C D D C + YI P + N + + F G + C GY+ PY I + +W +C SC ++P N + ++++ + A +C+DG+ + N + C +G W + C A C S + +VN K +FKC EG+ L+ + +C R G W S+ T CI CG PP I V+ + G+ Y C + GE TC SG LP C P D + K+ ++++ + V CN GY+L + C N W P CV C +PP +KY +++ + + S ++C GY LS C K G W K T C P KC PP +N L K + P +V++ C + L+G + CL P C+ + P
Sbjct: 1670 ISCGKPPRLENGFYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWNGISPSCLD-VDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVSC---DEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMV--------DNAQMLCNTEGNWVPPDGKEIPNCIADFCERPS----SVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKK-RTCLASGEWSGRLPA--------CHPGSCDDPPKLENGFVKSKTGLLYE-----SKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCE-KPPPVKYGSMKGENFEVGSKVEFFCEDGY----------ELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYEN------------HLVLKEV-PNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPP 2215 HSP 9 Score: 76.6406 bits (187), Expect = 1.204e-13 Identity = 133/569 (23.37%), Postives = 209/569 (36.73%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGY----------------------ALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIK--------CEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN--FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIH-NRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
G C+E ++C+ P + NG+ + + VG Q+ ++C GY L GP C ++ + S P+C + C P + Y H S+ F G+ C +GY + ++ GN D + CE+ S LE + + + +++ C +GF + T R +C G+W S T C + C E +NG V G + S+ + C +GY + G R C G W G C +C PP++ V + + ++ Y C L+G + W + P C LL C KP V + K NF + G+ V C GYEL+ D+ C NG W+ P C+ + C PP + V + R+ C G+ + +G L + + N P C+ C+ PP GE S+ ++ VKY C + LKG + C +G WS P P C I
Sbjct: 1762 GKKCLE-PVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVS--CDEPPNVDYASSH--SSHRLF--GDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFK------CMEGFVLNTTA--------RIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRV----CQLNRHWYSESPPTCVLLTCEKPPPVKYGSM------KGENFEV------GSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQ-DPPLYENHLVLKEVPNEVGIVRFSCKEGHVL----EGSSVLKCLPSQQWND----SFPL--CKLVFCSSPPELAYGEPI-------------SVPSLYFGSTVKYTCVDGFLLKGESVITCNASGMWS-PDFPNCSPI 2268 HSP 10 Score: 72.4034 bits (176), Expect = 2.298e-12 Identity = 55/185 (29.73%), Postives = 82/185 (44.32%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG 941
+C+ P QP NGHA + + VG V Y C++GY L+G C N S P C + + C IP + + DF G+ V I C+ GY+ + + CN +E W +KCEK SCG +NG R MY + + + C G+ + + R C +G W+
Sbjct: 3126 RCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPIC--KANPCPVPFVIPENAILTET---DFYVGQKVSIKCRKGYQ--LQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMY---HQFGDVVTYSCYSGYMLL--------GSFRSVCLENGTWTA 3292 HSP 11 Score: 64.6994 bits (156), Expect = 5.520e-10 Identity = 55/194 (28.35%), Postives = 84/194 (43.30%), Query Frame = 3
Query: 942 DTAICTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNS--DILPACYNGSWN 1502
+ ++C + CPEL PPENG V + N ++ +CK GY L GS++R C G W GS++TC VR C + ++ + T++G C L G + L G S W K P+C +HC F + + N + +G CN G+ L+ D + NG W+
Sbjct: 346 EGSVCKVVHCPELRPPENGYFVQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSSDTSYGTMCIAYCNDGYVLEGSSKLLCLG----SSQWDSK-VPQCKEMHCPVFHKPNGVLSSPSN------CGQEPAKYGYSCHVGCNKGFMLSGVKDKIKCVANGKWS 528 HSP 12 Score: 62.7734 bits (151), Expect = 1.926e-9 Identity = 89/386 (23.06%), Postives = 135/386 (34.97%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYAL-KGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEW--KYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH-GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEV-THGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAAC 1532
L C P +N G Y C+ GY + + + C + S + C + L S T + ++ ++ + + I+C+ GY S +GN W + + C SCG+ P++G + Y ++ CN GF++ + RR C D K C C PENG TV S ++C+ GY L G L +CT G W C C P I + E + G + KC+ L G+ + +TC + W V K+ + N I+ G V C GY L C NG+W P C +A C
Sbjct: 2949 LSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQS------TLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGN-WIPEVNNNICTPVSCGEPAAPEHGIVL-GTRYLFKDSLHYSCNHGFELNGPS--------RRICHID-KHQSTVGKCKKTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPICKANPCPVPFVIPENAILTETDFYVGQKVSIKCRKGYQLQGQ-AVITC---NADETWTDA------------NVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYMLLGSFRSVCLENGTWTAPPSC-KAVC 3300
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Match: SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:100493788]) HSP 1 Score: 111.694 bits (278), Expect = 1.638e-24 Identity = 136/559 (24.33%), Postives = 210/559 (37.57%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYE-LNSDILPACYNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEI------------------YLLGQ--SDRTRLTDKSIKP------------------IHNRVVKYE--------CHPLYRLKGPKIAVCLN-GHWSP 1919
++C P P NG +++ +G V + CK GY L G K C AN + + P+C + P +H + ++ + C GY+ S + + +W + C SCG+ NG+ + N YT+ CN+G+++ R C +G WSG T C AI C + NGEV G V ++C GY++ G+ C +G W+ + C +C PP +I + + Y C + G ++ + W P P CL P + + V N IM D+ T G V KC G++ L S L G W+ P C + C PPS+ + + S + RY C GY + + + + T +G W+K P CQ C PP+ N + Y++ Q S +T L D S P I N +Y+ C Y L GP + C+N G+W P
Sbjct: 2629 IECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCV------IISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQIS-KQWDGEEPICVPVSCGQPPMVINGKVI-GNEYTFSKTIEYVCNEGYRLYGEE--------IRTCLENGNWSGTTPSCLAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTR----QCLANGAWSGSP-PTCL----PCECPTPVV--------QNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPC-GPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCT---------KEGVWSK-PYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGNWIP 3143 HSP 2 Score: 105.531 bits (262), Expect = 1.493e-22 Identity = 99/376 (26.33%), Postives = 148/376 (39.36%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILP-ACY-NGSWN 1502
+ + C P +NG + +EY C GY L G R C N SG+ P C T I T + + G+++ C +GY+ + N W + CE C ED NG + ++N+ Y C G+++ ++ RQC A+G WSG C CP +NG + G T + KC+EG++L GS C G W C CGPPP I A + ++T Y C + + G++ L K G KP P C LL C P V +A ++ D T+G+ +C GY ++ D+ C +GSW+
Sbjct: 2743 VPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAIT------CKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCL-NDGTWNSNAPLCEPIHCEPPEDISNGY-LNSSNFKYNEYIHYVCFPGYEMHGSS--------TRQCLANGAWSGSPPTCLPCECP-TPVVQNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLC-----TKEGVWSKPYPNCQLLSCGLPPSVLNA------------VLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWS 3084 HSP 3 Score: 98.2117 bits (243), Expect = 2.664e-20 Identity = 126/522 (24.14%), Postives = 196/522 (37.55%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAK-VAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C GY +KG +KR C A+ SG P C + C P + V ++ V C GY+ + + + N + + P C +C K K G +M N+ S FC DG+++ + CQ +G+W T C C + EN V+ I F CKEG+ L GS + KC W+ S C + C PPE+ + + ++ + G+ +Y C L GE S +TC N SG W P +C P + + ++ + +T + C GYEL + C +G W P C CS + + F SL + Y C+ G+ R +G L+ + G W P C+ C P NG + S + ++ + C P ++L G + C WS P C
Sbjct: 2057 IPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGS--CDDPPKLENGFVK---SKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPPPVKYG-SMKGENFEVGSKVEFFCEDGYELS--------GDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGE-SVITC----NASGMWSPD-----FPNCSPIECPQPEEILN------GIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCS-KAKEILNGKFSFQSLNYGQTITYTCNRGF----RLEGQNVLTCL-----ETGEWNSNPPI-CKEITCDPPQGIDNGFVEGADYS-------------YGAMIIFSCMPGFQLVGLAMQTCEESGWS-SSTPVC 2523 HSP 4 Score: 96.6709 bits (239), Expect = 6.796e-20 Identity = 126/525 (24.00%), Postives = 202/525 (38.48%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPR-----CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+ + C+ NG + VG ++ Y C GY ++G K C + + + P LC P + + N +FK E + +C GYE S NG W P C C +NG ++ S++I+ C +GFK+ +++ CQ+ GKWS C + C N + G +T + C GY + G CT+EG W C + +CG PP ++ A + ++ T+G+ A Y+C+ + + S TC E W P + C P + I N T + ++ +T C GY L C N N+IP C +C P + ++ V Y C+ G+ I E + I G W+ + + C+ +C P P+N G ++ +T S V+Y+C Y L+G +A C NG WS P +P C+
Sbjct: 2801 LAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAP-------LCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANG-AWSGSPPTCLPCEC-PTPVVQNGIMSGDDFTCGHSVSIK-CREGFKLLGSSE--------LTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLE---DGSWSPGD-----IVCVPKKCLLQSTLIQIKNDETEYDINKTIT------IVCKEGYTLTGPSTSTCMNDG-NWIPEVNNNICTPVSC-GEPAAPEHGIVLGTRYLFKDSVLYQCNAGFEI---HGPTERVCQI------NGLWSDVEPQ-CKKTRCEVPQQPEN------GHAEYENVTVGS-------TVRYQCQNGYTLEGEDLAECTTNGTWSHP-VPICK 3267 HSP 5 Score: 94.7449 bits (234), Expect = 3.384e-19 Identity = 102/447 (22.82%), Postives = 155/447 (34.68%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPT 1715
+ C PP N N S D + Y C +GY ++G + C S P C + +P + ++ D + G CQ+GY W I C K C L KN T Y+ N T + C +G+ + + C DG W + ICT + C E + PE+G V+G ++C G+++HG R C G W C C P + YE T G+ Y+C++ TL GE E W P P C + P I EN + + G V KC GY+L + C + +W E P +++ +R + + + Y C+ GY + L + + G WT P+
Sbjct: 2976 VPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQ------LLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIV----CKEGYTLTGPS--------TSTCMNDGNWIPEVNNNICTPVSCGEPAAPEHGIVLGTRYLFKDSVLYQCNAGFEIHGPTERVCQINGLWSDVEPQCKKTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGE----DLAECTTNGTW-SHPVPICKANPCP-----VPFVIPEN----AILTETDFYVGQKVSIKCRKGYQLQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYML---------LGSFRSVCLENGTWTAPPS 3381 HSP 6 Score: 91.6633 bits (226), Expect = 2.539e-18 Identity = 134/529 (25.33%), Postives = 199/529 (37.62%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKC-NKGNW-TKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHW--SPPQMPTCE 1940
+C EI C PP NG + G + ++C G+ L G + C+ + S S P C TD C P+I + Q + + KI+ +D K I N I + L+ + + Y Y + I CN+G++I + C+ DG W+G C I C + PENG + NT+ S F+CK GY+L+GS C W+ C++ +C P +I+ T+ + YKC + G S TC G EP C+ P + I N K ++ +E T + CN GY L + + C NG+W+ P C+ C K ST ++ + + C G I R + + + C N G W + P C+P C P NG L + K +N + Y C P Y + G CL NG W SPP CE
Sbjct: 2465 ICKEI--TCDPPQGIDNGFVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEES-GWSSSTPVCL-HTD-CGLPPHIDFGQYTIVTFEE--------KIL----TDDELKHSIFGVSN-------IILSPTTTSNTLKTENHSENSQLSEYLYGTNVIYSCNNGYEILGMS--------VLTCKEDGTWNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYG-LSQRTCQISKQWDG----EEPICV----PVSCGQPPMVI--NGK----VIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC-------KIST----TVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPL--CEPIHCEPPEDISNG-----------YLNSSNFK--YNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCLPCE 2920 HSP 7 Score: 84.7297 bits (208), Expect = 4.028e-16 Identity = 106/464 (22.84%), Postives = 162/464 (34.91%), Query Frame = 3
Query: 396 QCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQANLR-LSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-----------------------------DP--YKSHIIAKCNGNE---------------------------WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ-VDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA 1601
C P + NG + + LL +V Y C GY L G R CQ N S S P C T C P + Y + ++F+ G V+ C++GYE DP Y++H++ K NE W C+ C + G + + + S C DGF ++ + C A G WS D C+ I CP+ NG V T S + CK GY+L G+ C +G W G C C EI+ K ++++ +G Y C L G+ + LTC E W P + C P Q +D+ F+ + ++G + C G++L + C W + P C+ C PP + + ++ + L
Sbjct: 2118 SCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLT--CEKPPPVKYGSMKG----ENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGES--------VITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQ-NVLTCLETGE---WNSNPPICKEITCDPPQGIDNG------------FVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEESGWSSSTPVCLHTDC-GLPPHIDFGQYTIVTFEEKILT 2550 HSP 8 Score: 82.0333 bits (201), Expect = 2.244e-15 Identity = 131/572 (22.90%), Postives = 213/572 (37.24%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEP------ECTDQTDLCFS----APYIPYTQVHDNSNRDDFKNG----------EDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-------TFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW--NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
G C+E ++C+ P + NG+ + + VG Q+ ++C GY L G K C + + P ++ +C + + +P + S + +NG C+ GY C+ + +W +C SC ++P N + ++++ + A +C+DG+ + N + C +G W + C A C S + +VN K +FKC EG+ L+ + +C R G W S+ T CI CG PP I V+ + G+ Y C + GE TC SG LP C P D + K+ ++++ + V CN GY+L + C N W P CV C +PP +KY +++ + + S ++C GY LS C K G W K T C P KC PP +N L K + P +V++ C + L+G + CL P C+ + P
Sbjct: 1783 GKKCLE-PVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPCNEGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVSC---DEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMV--------DNAQMLCNTEGNWVPPDGKEIPNCIADFCERPS----SVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKK-RTCLASGEWSGRLPA--------CHPGSCDDPPKLENGFVKSKTGLLYE-----SKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCE-KPPPVKYGSMKGENFEVGSKVEFFCEDGY----------ELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYEN------------HLVLKEV-PNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPP 2300 HSP 9 Score: 82.0333 bits (201), Expect = 2.486e-15 Identity = 131/541 (24.21%), Postives = 201/541 (37.15%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYA--LKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIK--------CEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN--FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIH-NRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
+ C P + NG + S L Y CK+GY+ L GP C ++ + S P+C + C P + Y H S+ F G+ C +GY + ++ GN D + CE+ S LE + + + +++ C +GF + T R +C G+W S T C + C E +NG V G + S+ + C +GY + G R C G W G C +C PP++ V + + ++ Y C L+G + W + P C LL C KP V + K NF + G+ V C GYEL+ D+ C NG W+ P C+ + C PP + V + R+ C G+ + +G L + + N P C+ C+ PP GE S+ ++ VKY C + LKG + C +G WS P P C I
Sbjct: 1874 VTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVS--CDEPPNVDYASSH--SSHRLF--GDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFK------CMEGFVLNTTA--------RIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRV----CQLNRHWYSESPPTCVLLTCEKPPPVKYGSM------KGENFEV------GSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQ-DPPLYENHLVLKEVPNEVGIVRFSCKEGHVL----EGSSVLKCLPSQQWND----SFPL--CKLVFCSSPPELAYGEPI-------------SVPSLYFGSTVKYTCVDGFLLKGESVITCNASGMWS-PDFPNCSPI 2353 HSP 10 Score: 71.2478 bits (173), Expect = 4.916e-12 Identity = 134/594 (22.56%), Postives = 199/594 (33.50%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-----CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGF------KIQCT---------------------TDQFEDKNCRRQ-----CQADGKWSGDTAICTA-ILCPELSPPENGEVMGVWNTVNSIKTFKC--------------------------KEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCK---------------------------------------------SRSTLIGETSFLTCGE----VDN-------KSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-----RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++ C P + T H ++ + D K G + + C G++ I+ K N EW CE+ SCGK +NG YN + + + CN G+ ++ CT +D E +C C + GD C + C + ENG G V S F C EGY L G+ C +W + TC C P EI + T + A Y CK S L G+T++ C + VDN + W+P P+ K + +C + H ++ N + G+ V KC G+ LN+ C G +IP +C+ C PPS+K V + S+ Y C GYYI K S G W+ ++P C P C PP +NG + +T L ++ V Y C+P Y+L G + VC LN HW PTC + ++ P
Sbjct: 1627 KSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQ------IVGKPERQCLNLGEWDQPLPHCERISCGKPPRLENG--FYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWNGISPSCLDVDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPCNEGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACKTGYSYTLVGPDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQMLCNTEGNWVP-PDGKEIPNCIADFCERPSSVAHSILESVN---KAKFVSGSTVSFKCMEGFVLNTTARIECVRGG-QWIPSSLTIQCIPVRC-GEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLAS---------GEWSGRLPA--CHPGSCDDPPKLENGFV-----KSKTGL-------LYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPP 2183 HSP 11 Score: 64.6994 bits (156), Expect = 5.674e-10 Identity = 55/194 (28.35%), Postives = 84/194 (43.30%), Query Frame = 3
Query: 942 DTAICTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNS--DILPACYNGSWN 1502
+ ++C + CPEL PPENG V + N ++ +CK GY L GS++R C G W GS++TC VR C + ++ + T++G C L G + L G S W K P+C +HC F + + N + +G CN G+ L+ D + NG W+
Sbjct: 361 EGSVCKVVHCPELRPPENGYFVQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSSDTSYGTMCIAYCNDGYVLEGSSKLLCLG----SSQWDSK-VPQCKEMHCPVFHKPNGVLSSPSN------CGQEPAKYGYSCHVGCNKGFMLSGVKDKIKCVANGKWS 543
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Match: SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:100493788]) HSP 1 Score: 111.694 bits (278), Expect = 1.811e-24 Identity = 136/559 (24.33%), Postives = 210/559 (37.57%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYE-LNSDILPACYNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEI------------------YLLGQ--SDRTRLTDKSIKP------------------IHNRVVKYE--------CHPLYRLKGPKIAVCLN-GHWSP 1919
++C P P NG +++ +G V + CK GY L G K C AN + + P+C + P +H + ++ + C GY+ S + + +W + C SCG+ NG+ + N YT+ CN+G+++ R C +G WSG T C AI C + NGEV G V ++C GY++ G+ C +G W+ + C +C PP +I + + Y C + G ++ + W P P CL P + + V N IM D+ T G V KC G++ L S L G W+ P C + C PPS+ + + S + RY C GY + + + + T +G W+K P CQ C PP+ N + Y++ Q S +T L D S P I N +Y+ C Y L GP + C+N G+W P
Sbjct: 2548 IECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNEIPKCV------IISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQIS-KQWDGEEPICVPVSCGQPPMVINGKVI-GNEYTFSKTIEYVCNEGYRLYGEE--------IRTCLENGNWSGTTPSCLAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTR----QCLANGAWSGSP-PTCL----PCECPTPVV--------QNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPC-GPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCT---------KEGVWSK-PYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTCMNDGNWIP 3062 HSP 2 Score: 105.531 bits (262), Expect = 1.515e-22 Identity = 99/376 (26.33%), Postives = 148/376 (39.36%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILP-ACY-NGSWN 1502
+ + C P +NG + +EY C GY L G R C N SG+ P C T I T + + G+++ C +GY+ + N W + CE C ED NG + ++N+ Y C G+++ ++ RQC A+G WSG C CP +NG + G T + KC+EG++L GS C G W C CGPPP I A + ++T Y C + + G++ L K G KP P C LL C P V +A ++ D T+G+ +C GY ++ D+ C +GSW+
Sbjct: 2662 VPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITC------KISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCL-NDGTWNSNAPLCEPIHCEPPEDISNGY-LNSSNFKYNEYIHYVCFPGYEMHGSS--------TRQCLANGAWSGSPPTCLPCECP-TPVVQNGIMSGDDFTCGHSVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLC-----TKEGVWSKPYPNCQLLSCGLPPSVLNA------------VLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWS 3003 HSP 3 Score: 102.834 bits (255), Expect = 1.018e-21 Identity = 114/460 (24.78%), Postives = 168/460 (36.52%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQV-----------------------------------------HDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYN-GSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
+C EI C PP NG + G + ++C G+ L G + C+ + S S P C TD C P+I + Q +NS ++ G +V C NGYE S + K +G W C C DP+NG Y +N S+ + C G+++ + + C A+ +W+ + C I C + +G T S+ +KC +GYQ++G R C WDG C+ +CG PP ++ KV T EY C L GE TC E N SG P CL + K+ NN + E G + +CN GY++ C N G+WN P C C P + + + K++ Y C GY
Sbjct: 2384 ICKEI--TCDPPQGIDNGFVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEES-GWSSSTPVCL-HTD-CGLPPHIDFGQYTIVTFEEKILTDDELKHSIFGVSNIILSPTTTSNTLKTENHSENSQLSEYLYGTNVIYSCNNGYEILGMSVLTCKEDGT-WNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFE-CKPGYELNGSD--------KSICLANKQWNNEIPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQISKQWDGEEPICVPVSCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGE-EIRTCLENGNWSG----TTPSCL-------AITCKISTTVNNGE---VTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEP-PEDISNGYLNSSNFKYNEYIHYVCFPGY 2812 HSP 4 Score: 101.293 bits (251), Expect = 2.912e-21 Identity = 136/526 (25.86%), Postives = 211/526 (40.11%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN---LRLSGSE-PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEW--KYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKT-FKCKEGYQLHGSHLRKCTREGNW-DGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSWN-FIPRCVEAACSARPPSMKYST-VRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW 1913
CM + P V + H++H L GD Y C GY++ + C + G E P C D C + ++ + ++ N+ F +G V C G+ + I +C G +W I+C CG+ KNG + NY++ S+ C+ G+ I+ +R C A G+WSG C C + ENG V + K + C GY+L GS++R C +W S TC++ C PP + + + E G++ E+ C+ L G+ S+ TC K+G W K P C+ P + +Y EN+ ++ + VR C G+ L S +L + WN P C CS+ PP + Y + SL S +Y C G+ L+ + + I CN C P +C +P NG + + G LT S Y C P Y L G +C +G+W
Sbjct: 1850 CMAVSCDEPPNVDYASSHSSHR--LFGDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCI--ADFCERPSSVAHS-ILESVNKAKFVSGSTVSFKCMEGFVLNTTARI--ECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGY-VSGTNYSFGSVVAYSCDKGYYIKGEK--------KRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPPPVKYGSMKGENFEVGSKVEFFCEDGYELSGDLSW-TC----QKNGEWDKKQTPTCM----PSKCQDPPLY--ENH----LVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSS-PPELAYGEPISVPSLYFGSTVKYTCVDGFL--LKGESV--------ITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQG------LTFLS-------AALYTCKPGYELIGNSTLICGADGYW 2320 HSP 5 Score: 92.8189 bits (229), Expect = 1.309e-18 Identity = 127/541 (23.48%), Postives = 191/541 (35.30%), Query Frame = 3
Query: 567 QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-----CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG---------------------------DTAICTAI--------------LCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWD--------GSNST--------------CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-----RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++ C P + T H ++ + D K G + + C G++ I+ K N EW CE+ SCGK +NG YN + + + QC + + R C +G W+G + ICT I C + ENG G V S F C EGY L G C G WD G ++ C+ +C PP + +A G A Y C +++ L + + W+P P+ K + +C + H ++ N + G+ V KC G+ LN+ C G +IP +C+ C PPS+K V + S+ Y C GYYI K S G W+ ++P C P C PP +NG + +T L ++ V Y C+P Y+L G + VC LN HW PTC + ++ P
Sbjct: 1610 KSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQ------IVGKPERQCLNLGEWDQPLPHCERISCGKPPRLENG--FYNAEDLFAGSTVTY-------QCNIGYYLLGDSRMFCTDNGSWNGISPSCLDVDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQML----CNTEGNWVP-PDGKEIPNCIADFCERPSSVAHSILESVN---KAKFVSGSTVSFKCMEGFVLNTTARIECVRGG-QWIPSSLTIQCIPVRC-GEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLAS---------GEWSGRLPA--CHPGSCDDPPKLENGFV-----KSKTGL-------LYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCEKPP 2102 HSP 6 Score: 91.2781 bits (225), Expect = 3.724e-18 Identity = 125/529 (23.63%), Postives = 199/529 (37.62%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPR-----CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMP----TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+ + C+ NG + VG ++ Y C GY ++G K C + + + P LC P + + N +FK E + +C GYE S NG W P C C +NG ++ S++I+ C +GFK+ +++ CQ+ GKWS C + C N + G +T + C GY + G CT+EG W C + +CG PP ++ A + ++ T+G+ A Y+C+ + + S TC E W P + C P + I N T + ++ +T C GY L C N N+IP C +C P + ++ V Y C+ G+ + +G D + W P C +C P P+N G ++ +T S V+Y+C Y L+G +A C NG WS P +P C+
Sbjct: 2720 LAITCKISTTVNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAP-------LCEPIHCEPPEDISNGYLNSSNFKYNEYIHYVCFPGYEMHGSSTRQCLANG-AWSGSPPTCLPCEC-PTPVVQNGIMSGDDFTCGHSVSIK-CREGFKLLGSSE--------LTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLE---DGSWSPGD-----IVCVPKKCLLQSTLIQIKNDETEYDINKTIT------IVCKEGYTLTGPSTSTCMNDG-NWIPEVNNNICTPVSC-GEPAAPEHGIVLGTRYLFKDSLHYSCNHGFEL----NGPSRRICHIDKQ-----WIPPPPTCVISLCHNTRCEVPQQPEN------GHAEYENVTVGS-------TVRYQCQNGYTLEGEDLAECTTNGTWSHP-VPICK 3191 HSP 7 Score: 88.9669 bits (219), Expect = 1.832e-17 Identity = 102/452 (22.57%), Postives = 157/452 (34.73%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVR-----NCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPT 1715
+ C PP N N S D + Y C +GY ++G + C S P C + +P + ++ D + G CQ+GY W I C K C L KN T Y+ N T + C +G+ + + C DG W + ICT + C E + PE+G V+G + C G++L+G R C + W TC++ C P + YE T G+ Y+C++ TL GE E W P P C + P I EN + + G V KC GY+L + C + +W E P +++ +R + + + Y C+ GY + L + + G WT P+
Sbjct: 2895 VPCGPPPSIPNAFINGSSSTDEDAIRYNCVAGYIMQGKSELLCTKEGVWSKPYPNCQ------LLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQDVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIV----CKEGYTLTGPS--------TSTCMNDGNWIPEVNNNICTPVSCGEPAAPEHGIVLGTRYLFKDSLHYSCNHGFELNGPSRRICHIDKQWIPPPPTCVISLCHNTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGE----DLAECTTNGTW-SHPVPICKANPCP-----VPFVIPEN----AILTETDFYVGQKVSIKCRKGYQLQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMYHQFGDVVTYSCYSGYML---------LGSFRSVCLENGTWTAPPS 3305 HSP 8 Score: 84.7297 bits (208), Expect = 3.917e-16 Identity = 106/464 (22.84%), Postives = 162/464 (34.91%), Query Frame = 3
Query: 396 QCQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQANLR-LSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-----------------------------DP--YKSHIIAKCNGNE---------------------------WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ-VDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA 1601
C P + NG + + LL +V Y C GY L G R CQ N S S P C T C P + Y + ++F+ G V+ C++GYE DP Y++H++ K NE W C+ C + G + + + S C DGF ++ + C A G WS D C+ I CP+ NG V T S + CK GY+L G+ C +G W G C C EI+ K ++++ +G Y C L G+ + LTC E W P + C P Q +D+ F+ + ++G + C G++L + C W + P C+ C PP + + ++ + L
Sbjct: 2037 SCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLT--CEKPPPVKYGSMKG----ENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPELAYGEPISVPSLYFGSTVKYTCVDGFLLKGES--------VITCNASGMWSPDFPNCSPIECPQPEEILNGIVDVQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYGQTITYTCNRGFRLEGQ-NVLTCLETGE---WNSNPPICKEITCDPPQGIDNG------------FVEGADYSYGAMIIFSCMPGFQLVGLAMQTCEESGWSSSTPVCLHTDC-GLPPHIDFGQYTIVTFEEKILT 2469 HSP 9 Score: 83.5741 bits (205), Expect = 8.452e-16 Identity = 138/600 (23.00%), Postives = 207/600 (34.50%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLC--------------FSAPYI----------------------PYTQVHDNSNRDDFKNGEDVKIICQNGYED------------------PYK---SHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-------TFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW--NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
+ C P + NG N L G V Y C GY L G + +C N +G P C D D C + YI P + N + + F G + C GY+ PY I + +W +C SC ++P N + ++++ + A +C+DG+ + N + C +G W + C A C S + +VN K +FKC EG+ L+ + +C R G W S+ T CI CG PP I V+ + G+ Y C + GE TC SG LP C P D + K+ ++++ + V CN GY+L + C N W P CV C +PP +KY +++ + + S ++C GY LS C K G W K T C P KC PP +N L K + P +V++ C + L+G + CL P C+ + P
Sbjct: 1674 ISCGKPPRLENGFYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWNGISPSCLD-VDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVSC---DEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMV--------DNAQMLCNTEGNWVPPDGKEIPNCIADFCERPS----SVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKK-RTCLASGEWSGRLPA--------CHPGSCDDPPKLENGFVKSKTGLLYE-----SKVIYACNPGYKLVGSNVRVCQLNRHWYSESPPTCVLLTCE-KPPPVKYGSMKGENFEVGSKVEFFCEDGY----------ELSGDLSWTCQKNGEWDKKQTPTCMPSKCQDPPLYEN------------HLVLKEV-PNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPP 2219 HSP 10 Score: 76.2554 bits (186), Expect = 1.556e-13 Identity = 133/569 (23.37%), Postives = 209/569 (36.73%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGY----------------------ALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIK--------CEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN--FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIH-NRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
G C+E ++C+ P + NG+ + + VG Q+ ++C GY L GP C ++ + S P+C + C P + Y H S+ F G+ C +GY + ++ GN D + CE+ S LE + + + +++ C +GF + T R +C G+W S T C + C E +NG V G + S+ + C +GY + G R C G W G C +C PP++ V + + ++ Y C L+G + W + P C LL C KP V + K NF + G+ V C GYEL+ D+ C NG W+ P C+ + C PP + V + R+ C G+ + +G L + + N P C+ C+ PP GE S+ ++ VKY C + LKG + C +G WS P P C I
Sbjct: 1766 GKKCLE-PVKCKDPGEIENGNYSGNHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYTLVGPDTINCSSSGKWSEHIPQCMAVS--CDEPPNVDYASSH--SSHRLF--GDTAYYYCSDGYSMVDNAQMLCNTEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFK------CMEGFVLNTTA--------RIECVRGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEWSGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRV----CQLNRHWYSESPPTCVLLTCEKPPPVKYGSM------KGENFEV------GSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSKCQ-DPPLYENHLVLKEVPNEVGIVRFSCKEGHVL----EGSSVLKCLPSQQWND----SFPL--CKLVFCSSPPELAYGEPI-------------SVPSLYFGSTVKYTCVDGFLLKGESVITCNASGMWS-PDFPNCSPI 2272 HSP 11 Score: 72.4034 bits (176), Expect = 2.590e-12 Identity = 55/187 (29.41%), Postives = 83/187 (44.39%), Query Frame = 3
Query: 390 DLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG 941
+ +C+ P QP NGHA + + VG V Y C++GY L+G C N S P C + + C IP + + DF G+ V I C+ GY+ + + CN +E W +KCEK SCG +NG R MY + + + C G+ + + R C +G W+
Sbjct: 3134 NTRCEVPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPIC--KANPCPVPFVIPENAILTET---DFYVGQKVSIKCRKGYQ--LQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGMY---HQFGDVVTYSCYSGYMLL--------GSFRSVCLENGTWTA 3302 HSP 12 Score: 64.3142 bits (155), Expect = 6.326e-10 Identity = 55/194 (28.35%), Postives = 84/194 (43.30%), Query Frame = 3
Query: 942 DTAICTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV--AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNS--DILPACYNGSWN 1502
+ ++C + CPEL PPENG V + N ++ +CK GY L GS++R C G W GS++TC VR C + ++ + T++G C L G + L G S W K P+C +HC F + + N + +G CN G+ L+ D + NG W+
Sbjct: 361 EGSVCKVVHCPELRPPENGYFVQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSSDTSYGTMCIAYCNDGYVLEGSSKLLCLG----SSQWDSK-VPQCKEMHCPVFHKPNGVLSSPSN------CGQEPAKYGYSCHVGCNKGFMLSGVKDKIKCVANGKWS 543
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Match: Svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:MGI Symbol;Acc:MGI:1928849]) HSP 1 Score: 131.724 bits (330), Expect = 6.965e-31 Identity = 136/516 (26.36%), Postives = 202/516 (39.15%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP---KPEPKCLLH-CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIP---RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW 1913
++C+ P P NGH++ I VG V ++C G+ L G C P C + P +P D S F G V C GY +G+ W + CE C + ED NG+ + + TY SIA C +G+ +Q + +C A G W C + C E ++ + G T + + CKEGY L G C G W+ SN C+ +C PP + A G A Y C +L + S L C N W+P + P+C+ H C+ + S I E+ F G+ V KC G+ LN+ C G W+ P +C+ C PPS+ + ++ Y CH G+YI K + G W+K PT C P C +PP +NG +L + RT ++ +++C+P Y+ G + VC N HW
Sbjct: 1786 VKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSC---EAISCGVPPVPENGGVDGSA---FTYGSKVVYRCDKGYTLSGDEESACLASGS-WSHSSPVCELVKCSQPEDINNGKYIL-SGLTYLSIASYSCENGYSLQGPS--------LLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSL-ADNSQLICNAQGN---WVPPAGQAVPRCIAHFCE--KPPSVSYSILESVSKAKFAA------GSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRC-GEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEAT---------GQWSK-PTPTCHPVSCNEPPKVENG--FLEHTTGRTFESE----------ARFQCNPGYKAAGSPVFVCQANRHW 2250 HSP 2 Score: 126.716 bits (317), Expect = 2.521e-29 Identity = 154/573 (26.88%), Postives = 229/573 (39.97%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTD-------------LCFSAPYI-----PYTQVHDN-----------------SNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-----NFIPRCVEAACSARPPSMKYSTVRFLS---LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGN-WTKMP-TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++C P NG + G V Y C SGY L G + +C N +G P C D + L + Y+ PYT N S+ + + G V C G+E S I G EW CE SCG P+NG + + +TY S + C+ G+ + + D+ C A G WS + +C + C + NG+ + T SI ++ C+ GY L G L +CT G+WD + +C + +CG PP + A + T G Y CK TL G + V +G +CL + C +P VD H + +T + + D + C GY L + C G+W +PRC+ C +PPS+ YS + +S S+ + C G+ L+T I+C +G W+ P + C P +C +PP+ NG Y G T+ S VV Y CH + +KG K + C G WS P PTC + +E P
Sbjct: 1687 IRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETG-EWDRLRPSCEAISCGVPPVPENG-GVDGSAFTYGSKVVYRCDKGYTL--SGDE------ESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTI-----VCQANGKWNSSNHQCLAVSCDEPPNVD------HASPETAHRLFGDTAFY------YCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCE-KPPSVSYSILESVSKAKFAAGSVVSFKCMEGF----------VLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANG--YPSG-------TNYSF----GAVVAYSCHKGFYIKGEKKSTCEATGQWSKP-TPTCHPVSCNEPP 2207 HSP 3 Score: 118.242 bits (295), Expect = 1.146e-26 Identity = 115/434 (26.50%), Postives = 170/434 (39.17%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE--NGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFD 1676
I ++C PV P NG + + +G +Y+CK G+ L+G R C N + SG+ P C + C P + + DD+ + C +GY C N +W C CG P NGR + YT+Q C +GF ++ R C +G WSG T C + CP +PP+ NG G+ F C EGY L G+ C G WD C CGPP ++ + HG +Y+C + L G S C + SG P C P + + + N T ++ G V+ +C G++L C NG W+ +P C A C P++ + V SL D++ Y C GY + D + T I+
Sbjct: 2710 ISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRC--EAISCSK----PNPLWNGSIKGDDYSYLGVLYYECDSGYI--LNGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGR-VKGEEYTFQKEITYSCREGFILEGARS--------RICLTNGSWSGATPSCMPVRCP--APPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPS-RRCLPNGSWSGSSPS--------CLPCRCSTPIIQQGTINAT-------DLGCGKTVQIECFKGFKLLGLSEITCDANGQWSDVPLCEHAQCGPL-PTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWS 3107 HSP 4 Score: 111.694 bits (278), Expect = 1.162e-24 Identity = 127/511 (24.85%), Postives = 197/511 (38.55%), Query Frame = 3
Query: 429 HANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTD-QTDLCFSAP--YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCE 1940
HA+H L G V Y+C+ GY L G CQ + +G+ P C + DL + ++ +TQ G + C+ G+ SH+ +W +CE SC K NG ++ ++Y+Y + C+ G+ + + + +R CQ + W G +C + C P NG V G T T+ C+EG+ L G+ R C G+W G+ +C+ C PP++ + + C L G LTC +P CKP + F HG H++ +C GY+L+ + C NGSW+ P C+ CS P ++ T+ L + C G+ L + +I C+ G W+ +P C+ +C PT N I L G + VV Y C P Y ++G +C WS P PTCE
Sbjct: 2668 HASH--FLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQT---------TMGSAAQYSCKPGHIL-EGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNG-SIKGDDYSYLGVLYYECDSGYIL--------NGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPR-LTCQSNGTWDAEVPV--------CKPATCGPPA------DLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCST--PIIQQGTINATDLGCGKTVQIECFKGF----------KLLGLSEITCDANGQWSDVPL--CEHAQCGPLPTIPNA-IVLEGSLSE------------DNVVTYSCRPGYTMQGSSDLICTEKAIWSQP-YPTCE 3114 HSP 5 Score: 106.686 bits (265), Expect = 4.134e-23 Identity = 126/523 (24.09%), Postives = 204/523 (39.01%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYD-PIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD-TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH-GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDE-VTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C G+ +KG +K C+A + S P C + C P + + + R F++ + + C GY+ + + N W D P+ C +CGK +NG + ++ S CN+G+++ + CQ GKWS + C C E EN V+ + + T CKEG+ L G + KC G W+GS C + C PP I F A H G+ +Y C L G + L S W P P+C+ V + + N I+H + + + + C G+EL + C NG W P C C P + +S ++ Y+C G+ R +G ++L+ + G+W P C C+ P +NG ++ G R + ++ Y C P +++ G + C WS PTC
Sbjct: 2141 IPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVS--CNEPPKVENGFLEHTTGRT-FES--EARFQCNPGYKAAGSPVFVCQAN-RHWHSDAPLSCTPLNCGKPPPIQNG-FLKGESFEVGSKVQFVCNEGYELV--------GDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGSPTIL----CQADSTW-SSPLPECV-----------PVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIEC-PEPKEILNGQFSSVSFQYGQTITYFCDRGF----RLEGPKSLTCL-----ETGDWDMDPPS-CDAIHCSDPQPIENG--FVEGADYR-----------YGAMIIYSCFPGFQVLGHAMQTCEESGWS-SSSPTC 2607 HSP 6 Score: 96.6709 bits (239), Expect = 6.131e-20 Identity = 107/422 (25.36%), Postives = 160/422 (37.91%), Query Frame = 3
Query: 474 TCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCK-PFQVD--------------------------------SAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
+CK G+AL+GP C + + +GS P C + LC S P IP+ V +S F G VK +C +G+ I+ + + + W +C C + E+ NG ++ Y S + C GF++ N C +G+W G +C I CPE NG+ V T+ C G++L G C G+WD +C +C P I V +GA Y C ++G + TC E SGW P C+ + C P +D A EN K + +GT V C GYEL + C +G+WN P C+ C P + + + F S A+Y C G+ +
Sbjct: 2347 SCKEGHALQGPSVLKCLPSGQWNGSFPIC--KMVLCPSPPLIPF-GVPASSGALHF--GSTVKYLCVDGFFLRGSPTILCQAD-STWSSPLPECVPVECPQPEEILNG-IIHVQGLAYLSTTLYTCKPGFELV--------GNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVSFQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGH-AMQTCEE----SGW-SSSSPTCVPIDCGLPPHIDFGDCTKVRDGQGHFDQEDDMMEVPYLAHPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDL-PVAPENGFLHFTQTTMGSAAQYSCKPGHIL 2746 HSP 7 Score: 91.6633 bits (226), Expect = 2.193e-18 Identity = 85/359 (23.68%), Postives = 135/359 (37.60%), Query Frame = 3
Query: 381 MEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYT-YQSIAIQF-CNDGFK-------------------------------IQCTTDQFEDKNCRRQ------------------CQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPK 1304
M I + C P P NG ++ Y+C+ G+ L+G R R C N SG+ P C C + P +P + ++ D+ ++V C GY + + NG W + C+ +CG D G + N ++ Y IQ+ C G+K IQ T D C + C A+G+WS D +C C L N V+ + +++ T+ C+ GY + GS CT + W TC +CGPPP + A EA T+ ++ + +C + +T TC W+P+
Sbjct: 2824 MCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVR--CPAPPQVP----NGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGT-WDAEVPVCKPATCGPPADLPQG---FPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWS-DVPLCEHAQCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDSDTDTFTC---QQDGHWVPE 3168 HSP 8 Score: 87.0409 bits (214), Expect = 4.907e-17 Identity = 132/563 (23.45%), Postives = 207/563 (36.77%), Query Frame = 3
Query: 324 EYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKII----CQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNW----DGSNSTCIVRNCGPPPEI---VFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLK-HDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELPI 1967
E+DR + C++ CG+ PPV P NG + S G +V Y C GY L G + C A+ S S P C + +Q D +N +G I C+NGY S + +G+ W P C+ SCG+ K+ + +N+T+ + C +G+ + CQA+GKW+ C A+ C E ++ + C +GY L + C +GNW + CI C PP + + V+ G+ +KC L E W P P + C P + + TN+ + G V C+ G+ + + C G W+ P C +C+ PP ++ + + + +S AR+ C+ GY A S +F + N+ +W C P C KPP +NG +L G+S V++ C+ Y L G C +G WS P C E P+
Sbjct: 1833 EWDRLRP-SCEAISCGV----------PPV-PENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCE----------LVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGS-WDRAPPSCQLVSCGEPPIVKDA-VITGSNFTFGNTVAYTCKEGYTLAGPDTIV--------CQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKI----ECLRGGEWSPSP---LSVQCIPVRCGEPPSIANGYPSGTNY------SFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCN-EPPKVENGFLEHTTGRTFESEARFQCNPGYKAA--------GSPVFVCQANR-HWHSDAPLSCTPLNCGKPPPIQNG--FLKGESFEV-----------GSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPL 2327 HSP 9 Score: 85.8853 bits (211), Expect = 1.205e-16 Identity = 108/472 (22.88%), Postives = 171/472 (36.23%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEY---DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICT-AILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG--ETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+V S VK L + CP + N+ W ++ ++ V S + C ++ P ++P +G+ G +V C G+ + G +YC + + P C + C +P + + +DF G V C +GY S + NG+ P + C D + N N +Y C + ++GD C + C PENG G TV + TF C EG++L G C G WD +C +CG PP V A T+G++ Y+C TL G E++ L G + S P C L K E+ +I+ +T+ + C GY L L C +GSW+ P + PP +K + + + + Y C GY +A
Sbjct: 1581 YVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSV-PHLRPASGNRKP-----GSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHC--ERIRCG----LPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSY----------------------------VCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSS-------PVCEL---------VKCSQPEDINNGKYILSG-LTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLA 1995 HSP 10 Score: 80.1073 bits (196), Expect = 7.462e-15 Identity = 104/448 (23.21%), Postives = 161/448 (35.94%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE-TSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPS-MKYSTVRFLSLKHDSLARYYCHFGYYI--ALRKDGMETLSTIFDIKCNKGNWTKMPT 1715
QC P N L + V Y+C+ GY ++G C S P C + C P + ++ + K VK+ C GY + W + I C K C + R ++ + +++ C +GF E N CQ DG W + C ++C P +G V+G ++ S ++C GY+L G+ R C W G + C C P E K E TT G + C TL G + T N L KP P C + PF + V + E +V KC G+ L + + C + +W RC + +C PPS ++ + R + ++ + Y C+ GY + +LR +E G WT P
Sbjct: 3059 QCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLS--CGPPPTVANAVATGEAHTYESK----VKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVS-CAEGFT-------HEGVN-WSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNP-CPV---PFVIPENAV-----------LSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCG--PPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLE-----------NGTWTPSPV 3463 HSP 11 Score: 72.7886 bits (177), Expect = 1.413e-12 Identity = 91/388 (23.45%), Postives = 145/388 (37.37%), Query Frame = 3
Query: 441 SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEW----KYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD--TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF--IPRCVEAACSARPPSMKYSTV 1568
S G+ V YTCK GY L GP CQAN + + S +C + C P + H + G+ C +GY S +I GN W +C C K ++ + S+ C +GF + + + + +C G+WS + C + C E NG G + ++ + C +G+ + G C G W TC +C PP++ + + T ++A ++C G F+ N+ P L C P ++ K +N F+ + G+ V+ CN GYEL D C +G W+ P+CV C A PP ++ V
Sbjct: 1976 SNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVS--CDEPPNVD----HASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGN-WVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVL--------NTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVC---QANRHWHSDAP-----LSCTP--LNCGKPPPIQN----GFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKC-AEPPLLENQLV 2333 HSP 12 Score: 70.8626 bits (172), Expect = 4.696e-12 Identity = 66/247 (26.72%), Postives = 98/247 (39.68%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-KLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGS 1118
I + C P P +G + G + Y C GY L+G R+R CQ N + SG C + + C + P + + ++ +G + C GY E ++H A NG W + C+ C P+N Y Q+++I+ C +GF ++ N C D W+ A C I C S EN GV+ + T+ C GY L GS C G W S
Sbjct: 3233 IPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRE--NRCETPAEFP----NGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTA--NGT-WNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIK-CREGFLLK--------GNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPS 3461 HSP 13 Score: 60.4622 bits (145), Expect = 8.083e-9 Identity = 55/232 (23.71%), Postives = 88/232 (37.93%), Query Frame = 3
Query: 462 QVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVM--GVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG 1148
Q E C+ GY KG + C A + C P + +T +++ +D +C+ GY+ ++ CE C L+ P+NG + N + + A C GF + ++ CQ +G WSG + C CP L P++G + + N++ C EGY+L GS C WDG C+ R+C
Sbjct: 303 QFECICEKGYYGKG-LQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPED--------CVCREGYQRSGQT-----------------CEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHL--------CQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCA 500 HSP 14 Score: 53.9138 bits (128), Expect = 7.926e-7 Identity = 53/218 (24.31%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKN--GRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI 965
+E +R ++C + G V + + +C+ P + NG A G + ++C GY L+G + +C AN + P C + + C IP V + +F ++V I C+ G+ K + + C+ +E W + +CEK SCG +N R +Y Y Y + C G+ ++ + R C +G W+ + +C A+
Sbjct: 3269 LEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLC--KPNPCPVPFVIPENAVL---SEKEFYVDQNVSIKCREGFL--LKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVY---YQYGDMITYSCYSGYMLE--------GSLRSVCLENGTWT-PSPVCRAV 3467
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Match: Csmd1 (CUB and Sushi multiple domains 1 [Source:MGI Symbol;Acc:MGI:2137383]) HSP 1 Score: 115.546 bits (288), Expect = 6.751e-26 Identity = 114/472 (24.15%), Postives = 179/472 (37.92%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQT-DLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V+Y+CK G L G R CQ + SGS P C+ + C P T H + D+FK ++ C+ G++ + NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG W+ +C A+LC + P NG+V G + ++ C +GYQL S + C G W G C+ CG P +++ ++ T ++ +CK L+G +S TC G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2855 LAISCGHPGVPANAVLTGELFTYGATVQYSCKGGQILTGNSTRVCQEDSHWSGSLPHCSGNSPGFCGD----PGTPAHGSRLGDEFKTKSLLRFSCEMGHQLRGSAERTCLVNGSWSGVQPV-CEAVSCGNPGTPTNGMILSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLPNGIQFGTDFTFNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQSRPLCKAVLCNQPPPVPNGKVEGSDFRWGASISYSCVDGYQLSHSAILSCEGRGVWKGEVPQCLPVFCGDPGTPAEGRLSGKSFTFKSEVFIQCKPPFVLVG-SSRRTC----QADGIWSGIQPTCIDPAHTACPDPGTPHFGIQNSSKGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPAFGYTLVYTCHPGFFLA 3309 HSP 2 Score: 110.538 bits (275), Expect = 2.858e-24 Identity = 142/566 (25.09%), Postives = 215/566 (37.99%), Query Frame = 3
Query: 297 CTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLK---GPKIAVCLNGHWSPPQMPTCEFIMHDELP 1964
C AN E DR + C CG + P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + C+ G+++Q + R QC+++G+WS IC + C + EN G N S + + CK G+ L GS C G WD S C+ +CG P A + E T+GA +Y CK L G ++ + C E + SG LP HC +S + DE + +R C G++L C NGSW+ + P C +C + + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ P I +G W+ + P C+ ++ ++ P
Sbjct: 2602 CQANGTWSTEEDRPR---CKVISCGSLSF-----------PPNGNKIGTLTIYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGLTN-GTEFNLNDLVNFTCHTGYRLQGAS--------RAQCRSNGQWSSPLPICRVVNCSDPGSVENAVRHGQQNFPESFEYGTSVMYHCKTGFYLLGSSALTCMASGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGATVQYSCKGGQILTGNSTRV-CQEDSHWSGSLP--------HCSG---NSPGFCGDPGTPAHGSRLGDEFKTKSLLRFSCEMGHQLRGSAERTCLVNGSWSGVQPVCEAVSCGNPGTPTNGMILSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLPNGIQF---GTDFT----------FNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQSR-PLCKAVLCNQPP 3101 HSP 3 Score: 100.908 bits (250), Expect = 2.848e-21 Identity = 108/426 (25.35%), Postives = 157/426 (36.85%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN----LRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG--DTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N + P C Q C IP + + ++F V C G++ C + W + P C+ C +E + ++ N Y Q + + C+ F QCQA+G WS D C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H T F ++D V C+ GY L C NG W+ +P C CS P + VR S ++ + Y+C G+Y+
Sbjct: 2441 GGILNKTAGAVGSKVHYFCKPGYRMIGHSNATCRRNPVGVYQWDSMAPLC--QAVSC----GIPEAPGNGSFTGNEFTLDSKVTYECNEGFKLDASQEATTVCQEDGLWSNRGKPPTCKPVPCPSIEGQLSEHVLWRLVSGSLNEYGAQVL----------LSCSPGYFLQGQRLLQCQANGTWSTEEDRPRCKVISCGSLSFPPNGNKIGTLTIYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCGHPGNPAHGLTNGTEFNLNDLVNF------TCHTGYRLQGASRAQCRSNGQWSSPLPICRVVNCSD--PGSVENAVRHGQQNFPESFEYGTSVMYHCKTGFYL 2833 HSP 4 Score: 87.8113 bits (216), Expect = 3.282e-17 Identity = 128/588 (21.77%), Postives = 189/588 (32.14%), Query Frame = 3
Query: 102 LIKNSLNELFPQNQNYKSRFHKIRHQRHLFLNLINPMKSAQYKPECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDP-KNGRTMYNNNYTYQSIAIQFCNDGFKI--------------------------------------------------QCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGYELNSDILPACY---NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
L+ SLNE Q S + ++ QR L + + +P C V S ++ PNG TA C Y + C+ + G + C P VNGH + D V Y C G+ L G R C + + SG P C T C P H +N +F + V C GY S + NG +W C +C G +E+ ++G+ + ++ Y + + C GF + C Q N R CQ D WSG C+ C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + P +G+WN P C C+ +PP + V + + Y C GY ++
Sbjct: 2572 LVSGSLNEYGAQVLLSCSPGYFLQGQRLLQCQANGTWSTEEDRPRCKVISCGSLSFPPNGNKIGTLTIYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT--CGH----PGNPAHGLTNGTEFNLNDLVNFTCHTGYRLQGASRAQCRSNG-QWSSPLPICRVVNCSDPGSVENAVRHGQQNFPESFEYGTSVMYHCKTGFYLLGSSALTCMASGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGATVQYSCKGGQILTGNSTRVCQEDSHWSGSLPHCSGNSPGFCGDPGTPAHGSRLGDEFKTKSLLRFSCEMGHQLRGSAERTCLVNGSWSGVQPVCEAVSCGNPGTPTNGMI--------------LSSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLPNGIQFGTDFTFNKTVSYQCNPGYLMEPPTSPTIRCTKDGTWNQSRPLCKAVLCN-QPPPVPNGKVEGSDFRWGASISYSCVDGYQLS 3130 HSP 5 Score: 58.9214 bits (141), Expect = 2.460e-8 Identity = 44/187 (23.53%), Postives = 73/187 (39.04%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V CK + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + + + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3155 CGDPGTPAEGRLSGKSFTFKSEVFIQCKPPFVLVGSSRRTCQADGIWSGIQPTCIDPAHTACPDPGTPHFGIQNSSK--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPAFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3330 HSP 6 Score: 53.5286 bits (127), Expect = 4.686e-8 Identity = 120/518 (23.17%), Postives = 183/518 (35.33%), Query Frame = 3
Query: 453 VGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSH------IIAKCNGNEWKY-DPIKCEKK-SCGKLEDPKNGRT----MYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+GD V+Y C GY L G C+ + L GS P C Q P +V S+ +I GY Y + I + N N + D + EK+ ++ D +G++ + + N+T QS N ++ +TD K + A A C S NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L T + D W + +P CKP S + + E+ + +G V C+ GY L L C NG+W+ PRC +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2278 IGDFVKYQCHPGYTLLGSDTLTCKLSSQLLFQGSPPTCEAQ---------CPANEVRTESS----------GVILSPGYPGNYFNSQTCAWSIKVEPNFNITLFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNH-LYLRWSTDHATSKKGFKIRYA------------APYCSLTSTLRNGGILNKTAGAVGSKVHYFCKPGYRMIGHSNATCRRNPVGVYQWDSMAPLCQAVSCGIPEAPGNGSFTGNEFTLDSKVTYECNEGFKLDASQEATTVCQEDGL--WSNRGKPPT---CKPVPCPSIEGQLSEH-VLWRLVSGSLNEYGAQVLLSCSPGYFLQGQRLLQCQANGTWSTEEDRPRCKVISCGSLSFPPNGNKIGTLTI-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2733 HSP 7 Score: 23.8682 bits (50), Expect = 4.686e-8 Identity = 10/23 (43.48%), Postives = 12/23 (52.17%), Query Frame = 1
Query: 1933 LVNLSCMTNYRFHGCIIARMTRN 2001
LVN +C T YR G A+ N
Sbjct: 2759 LVNFTCHTGYRLQGASRAQCRSN 2781
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Match: Csmd3 (CUB and Sushi multiple domains 3 [Source:MGI Symbol;Acc:MGI:2386403]) HSP 1 Score: 109.768 bits (273), Expect = 4.799e-24 Identity = 118/438 (26.94%), Postives = 166/438 (37.90%), Query Frame = 3
Query: 657 VKIICQNGYEDPYKSHIIAKCNG---NEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG--DTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPP----SMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXN----GEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQ 1925
V+ C G+ KS + + + + W C+ SCG + P NG + +Y + FCNDG+++ + CQ+DG WS T C I C EL P NG +G + S F C G+ L GS +R+C G W GS + C+ +CG P IV +V E + Y+C LIG +S C + N SG LP C P I+ F +D VT CN GY + C N W+ P + + P S + S + + + ++ Y C+ GY++ S++ + N G W K P C C P P N GE Y G + V Y C L G C LNGHWS Q
Sbjct: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLS------SKELTTATCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIG-SSVRICQQDHNWSGQLPS--------CVPVSCGHPGSPIYGRTSGNGFNFNDVVTF------SCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF--------GSSVLICQPN-GQWDK-PLPECIMIDCGHPGIPPNAVLSGEKYTFGST-----------------VHYSCTGKRSLLGQASRTCQLNGHWSGSQ 2876 HSP 2 Score: 107.457 bits (267), Expect = 2.751e-23 Identity = 90/310 (29.03%), Postives = 123/310 (39.68%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYA--LKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P P NG +VG V Y C+ GY L G R R C N SG P C T C + P I ++ +F G + IC GYE + + + NG W + +C K CG P G+ ++ YQS CN F + ++ R CQ DG WSG + C T C P +G + V S+ F CK+G+ L GS R C + W G CI +C P A V + +HG Y C+ L G T C + +G +P
Sbjct: 3002 ISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVT--CSTPPQISNGRLEGT----NFDWGFSISYICSAGYELSFPAVLTCVGNGT-WSGEVPQCLPKFCGDPGIPSQGKRE-GKSFIYQSEVSFSCNSPFILVGSS--------TRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVP 3295 HSP 3 Score: 102.834 bits (255), Expect = 7.052e-22 Identity = 115/443 (25.96%), Postives = 159/443 (35.89%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGY--ELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P+ G + + D V ++C GY ++GP K CQAN + S P C + C S P IP ++ +F G V C GY S +I + NG +W +C CG P N + YT+ S CT + R CQ +G WSG C T C + P +G S F C GY L+GS R C G+W G C CG P KV + TT + Y C L G S C SG LP +C + D+ G +V C GY ELN + C NG+W+ +P C CS PP + + + Y C GY ++
Sbjct: 2685 VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVC--KVVNC-SDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG-QWDKPLPECIMIDCGHPGIPPNA-VLSGEKYTFGSTV--------HYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGP-SVRQCTANGTWSGSLP--------NCTIISCGDPGI------PANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCST-PPQISNGRLEGTNFDWGFSISYICSAGYELSF 3098 HSP 4 Score: 95.9005 bits (237), Expect = 8.860e-20 Identity = 136/549 (24.77%), Postives = 198/549 (36.07%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYAL--KGPRKRYCQANLRLS--GSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV----FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCV--EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDE--LPISWLYYRSD 1991
+ C P P NG + LVG +V Y C GY L K CQ++ S P C + C P P + N G C G+ + +C + W +C CG E NG+ + NY Y+ + CN GF++ ++ R CQ D WSG C + C P G G N + TF C GY + G +C W C V NC P +K+ + T+G Y C L G +S L C +G KP P+C++ +D I N + ++ T G+ V C L C NG W+ P C P + + + + + S R+ C GY + G E + + + G+WT E C+ +C P T NG+++ + D T + I Y C Y L GP + C NG WS +P C I + +P + L Y D
Sbjct: 2526 ISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVIS--CGELPTPP----NGNKIGTQTSYGSTAIFTCDLGFM--LVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVI-GENYGYRDTVVYQCNPGFRLIGSS--------VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG-SSVLIC----QPNGQWDKPLPECIM------IDCGHPGIPPN----AVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILY----GSEERTCL-----SNGSWTGRQPE-CKAVQCGNPGTTANGKVFRI---DGTTFSSSVI---------YSCLEGYILSGPSVRQCTANGTWS-GSLPNCTIISCGDPGIPANGLRYGDD 3019 HSP 5 Score: 94.3597 bits (233), Expect = 2.896e-19 Identity = 146/599 (24.37%), Postives = 217/599 (36.23%), Query Frame = 3
Query: 231 PECHVKSLDNVKHLPNGC-----PSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGR---TMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC---IVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTL--IGETSFLTCGE-----VDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVRFL-SLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
P C V S + PNG S TA C + + + C+ G + C P VNG D V Y C G+ L G R CQ + SG P C + C P + ++ ++ + F + V C GY + P K A+C N +W + P C+ +C P N + + + N+TY ++ CN G+ F + CQ +G+W C I C P N + G T S + C L G R C G+W GS C CG P HG++ E +++ST+ +T ++ G + N S +PE K + P + KV+ D T + V C GY L+ + C NG+W+ +P C +C P + + +R+ Y C GY I L + T +T G W+ MPT C+ C+ PP NG RL + + Y C Y L P + C+ NG WS ++P C
Sbjct: 2583 PRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGH----PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK----AQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGY--------FLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDP----------GTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVF-----------RIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGD--PGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTT-------NGTWSGVMPT--CRAVTCSTPPQISNG-----------RLEGTNFD--WGFSISYICSAGYELSFPAVLTCVGNGTWS-GEVPQC 3117 HSP 6 Score: 90.8929 bits (224), Expect = 3.480e-18 Identity = 117/461 (25.38%), Postives = 162/461 (35.14%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANH-SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI--VRNCGPPPEIVFAKVAYEATTHGAQ----AEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLH-CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDI--------------LPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYY-IALRKDGMETLSTIFDIKCNKGNWT 1703
+QC P NG V Y+C GY L GP R C AN SGS P CT + P IP + DDF G++V +CQ GY + C N W C +C NGR + N+ + C+ G+++ C +G WSG+ C C + P G+ G S +F C + L GS R C +G W GS+ CI R P + + + T G Q ++ CK L G T+ TC SG +P+C+ H CK E+ N + D +HG + C G+ L +P C GS + A + P LS+ D A+ Y G Y RK M T F+ + N T
Sbjct: 2943 VQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTI---ISCGDPGIPANGLRYG---DDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGR-LEGTNFDWGFSISYICSAGYELSFP--------AVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGV--PRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTT-RTCLPDLTWSGI----QPECIPHSCKQ----------PESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPK---------LSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT 3362 HSP 7 Score: 58.5362 bits (140), Expect = 3.226e-8 Identity = 52/226 (23.01%), Postives = 87/226 (38.50%), Query Frame = 3
Query: 288 SKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
S C+A + + + CV + G V + C P P G + +V ++C S + L G R CQ + SGS P C + T P +P +N+ F+ G V+ C+ G+ + C + W +C SC + E P + + + ++ I C GF + T+ R C++D W+G +C A
Sbjct: 3087 SYICSAGYE--LSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTF--GFQVGSVVQFHCKKGHL--LQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEH-------RVCRSDNTWTGKVPVCEA 3299 HSP 8 Score: 57.3806 bits (137), Expect = 8.005e-8 Identity = 65/272 (23.90%), Postives = 102/272 (37.50%), Query Frame = 3
Query: 333 RAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQ-SIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLH-GSHLRKCTREGNWDGSNSTC 1130
R + C + G++ + C P Q NG + G + Y C +GY L P C N SG P+C + C P IP + + F +V C + + S + + +G P I+ + SC P++G NN + +Q +QF C G +Q +T R C D WSG C C + P + V+G+ + + C+ G+ L G+ R C + W G C
Sbjct: 3042 RVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPK--FC-GDPGIPSQGKREGKS---FIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQGST--------TRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVC 3297
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Match: Csmd2 (CUB and Sushi multiple domains 2 [Source:MGI Symbol;Acc:MGI:2386401]) HSP 1 Score: 109.383 bits (272), Expect = 7.417e-24 Identity = 138/532 (25.94%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWN------TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFL-SLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAV--CLNGHWSPPQMPTCEFIM 1949
+ C P +GH ++ + G ++C SGY L G R R C AN SGSE C C + P V+ + N ++F V C+ G+ S I + + + W C +CG +P NG T QF ND K C + R QC A G+WS C I C + EN V V + + +++C G+ L G+ C +G WD C++ +CG P A+++ ++ GA Y C + TL+G ++ + CG + +G LP HC S V + D G+ +R C+ G+ L C NGSW+ P C +C P + + V F L S Y C GYY + + C+ G WT E C C P P NG LG R +N+ V Y+C P Y ++ +++V C P C+ IM
Sbjct: 2659 ISCGELPTPPSGHRIGTMSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCL--AGHCGT----PEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRICQQD-HHWSGKTPFCVPITCGHPGNPVNGLTQ----------GSQFNLNDVVKFICNPGYIAEGAARSQCLASGQWSDTLPTCRIINCTDPGHQEN-SVRQVHTSGPHRFSFGTTVSYQCNHGFYLLGTPALSCQGDGTWDRPRPQCLLVSCGHPGSPPHAQMSGDSYIVGAVVRYSCTGKRTLVGNSTRM-CGLDGHWTGSLP--------HCSG---TSTGVCGDPGIPAHGIRLGDSFAPGSVMRFSCDAGHVLRGSSERMCQANGSWSGSQPECGVISC-GNPGTPSNARVVFSDGLVFSSSVVYECREGYYA----------TGLLSRHCSVNGTWTGSDPE-CTVINCGDPGIPANG--IRLGNDFR-----------YNKTVTYQCVPGYVMESHRVSVLSCTKDRTWNGTKPVCKAIM 3135 HSP 2 Score: 95.1301 bits (235), Expect = 1.606e-19 Identity = 113/450 (25.11%), Postives = 174/450 (38.67%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNG----EDVKIICQNGYEDPYKSHIIAK---CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILC--PELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMP 1712
C P P +G G + ++C +G+ L+G +R CQAN SGS+PEC + P P ++ R F +G V C+ GY Y + ++++ NG DP +C +CG P NG + N++ Y C G+ ++ + C D W+G +C AI+C P+L P NG+V+G T S ++ C EGYQL + C G+W G C CG P + ++ + + C + L+G C SG P L C D N + + + G+ V +C GY L C N +W+ P CV C +P + ++ V L L Y C G+ + + G E + D G+WT P
Sbjct: 2959 CGDPGIPAHGIRLGDSFAPGSVMRFSCDAGHVLRGSSERMCQANGSWSGSQPECGV---ISCGNPGTP------SNARVVFSDGLVFSSSVVYECREGY---YATGLLSRHCSVNGTWTGSDP-ECTVINCGDPGIPANGIRL-GNDFRYNKTVTYQCVPGYVME------SHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIP--NGKVVGSDFTWGSSVSYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPPRGRREDRGFSYRSSVSFSCHAPLVLVGSPRRF-CQSDGTWSGTQPSCIDPTLTTC----ADPGMPQFGIQNSSQGYQV------GSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCK-QPETPTHANVGALDLPSMGYTLIYSCQEGFSL---RGGSEHRTCKAD-----GSWTGKP 3366 HSP 3 Score: 93.2041 bits (230), Expect = 7.785e-19 Identity = 126/542 (23.25%), Postives = 195/542 (35.98%), Query Frame = 3
Query: 399 CQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYC----QANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYD-------PIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI--CTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSW-NFIPRCVEAACSARPPSMKYSTVRFL------SLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXX----XXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
C P P++G + G + + C +GY L G C Q S + P C L P P + ++ G C GY + A+C + W P+ C S +E + R ++ Y +Q+ + C+ G+ + + R CQA+G+WS ++ C I C EL P +G +G + + F C GY L GS +R+C G W GS C+ +CG P IV + E + Y+C++ LIG S C + + SG P C P H N + V+ CN GY C +G W + +P C C+ P + ++VR + + Y C+ G+Y+ G LS D G W + P C + P +G+ Y++G VV+Y C L G +C L+GHW+ +P C
Sbjct: 2471 CSLPKAPLHGFILGQTTTQPGGSIHFGCNTGYRLVGHSMAICTRHPQGYHLWSEAIPLCQA---LSCGLPDAPKNGIVFG---KEYTVGTKAVYSCNEGYHLQAGAEATAECLDTGLWSNSNVPPQCVPVTCPDISSISVEHGR-WRLIFETQYQFQAQLMLICDPGYY-------YTGQRVIR-CQANGRWSLGESMPTCQIISCGELPTPPSGHRIGTMSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIG-MSVRICQQDHHWSGKTP--------FCVPITCG------HPGNPVNGLTQGSQFNLNDVVKFICNPGYIAEGAARSQCLASGQWSDTLPTCRIINCTD--PGHQENSVRQVHTSGPHRFSFGTTVSYQCNHGFYLL----GTPALSCQGD-----GTWDR-PRPQCLLVSCGHPGSPPHAQMSGDSYIVGA-----------------VVRYSCTGKRTLVGNSTRMCGLDGHWT-GSLPHCS 2952 HSP 4 Score: 89.7373 bits (221), Expect = 8.144e-18 Identity = 77/303 (25.41%), Postives = 122/303 (40.26%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--TDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI---LCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCK 1226
++C D + G + + C P PVNG S + D V++ C GY +G + C A+ + S + P C + TD + QVH S F G V C +G+ + + +G W +C SCG P + + M ++Y ++ + CT + N R C DG W+G C+ +C + P +G +G S+ F C G+ L GS R C G+W GS C V +CG P A+V + + + Y+C+
Sbjct: 2756 VRICQQDHHWSGKTPFCVPITCGHPGNPVNGLTQGSQFNLNDVVKFICNPGYIAEGAARSQCLASGQWSDTLPTCRIINCTDPGHQENSV--RQVH-TSGPHRFSFGTTVSYQCNHGFYLLGTPALSCQGDGT-WDRPRPQCLLVSCGHPGSPPHAQ-MSGDSYIVGAVV--------RYSCTGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHGIRLGDSFAPGSVMRFSCDAGHVLRGSSERMCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSVVYECR 3045 HSP 5 Score: 85.8853 bits (211), Expect = 1.166e-16 Identity = 133/542 (24.54%), Postives = 202/542 (37.27%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ----ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKN----GEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPI--KCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNK---SGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFG-YELNSDILPACYNGSWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWT-KMPT-EGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
L C P P NG VG + Y+C GY L+ + + S P+C T P I V R F+ + +IC GY Y + +C N W C+ SCG+L P +G + Y + AI CN G+ + + R+C A+G WSG C A C P NG + G ++C+ G++L G +R C ++ +W G C+ CG P V T G+Q + I ++ G ++ SG P C +++C P +++ +H + + GT V +CN G Y L + L +G+W+ P+C+ +C PP + S ++ ++ RY C G TL C G+WT +P G C P P +G RL D S P V+++ C + L+G +C NG WS Q P C I
Sbjct: 2532 LSCGLPDAPKNGIVFGKEYTVGTKAVYSCNEGYHLQAGAEATAECLDTGLWSNSNVPPQCVPVT-----CPDISSISVEHGRWRLIFETQYQFQAQLMLICDPGYY--YTGQRVIRCQANGRWSLGESMPTCQIISCGELPTPPSGHRI-GTMSVYGATAIFSCNSGYTLVGSR--------VRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPV------NGLTQGSQ--FNLNDVVKFICNPGYIAEGAARSQCLASGQWSDTLPTCRIINCTDPGHQENSVRQVHTSGP-------HRFSFGTTVSYQCNHGFYLLGTPALSCQGDGTWDRPRPQCLLVSCGHPGSPPHAQMSGDSYIV---GAVVRYSC----------TGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHG----------IRLGD-SFAP--GSVMRFSCDAGHVLRGSSERMCQANGSWSGSQ-PECGVI 3015 HSP 6 Score: 78.5666 bits (192), Expect = 2.575e-14 Identity = 133/597 (22.28%), Postives = 210/597 (35.18%), Query Frame = 3
Query: 219 AQYKPECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDP-KNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLS-LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
+ P C + S + P+G TA C Y R + C+ + G + C P VNGH N V Y C++G+ L G R CQ + SG P C T C P V+ + F + VK IC GY E +S +A +W C +C G E+ + T + +++ + CN GF + T CQ DG W C + C P + ++ G V ++ + C L G+ R C +G+W GS C + CG P ++ G+ + C + L G + + C + SG +P+C ++ C P +A+V + D + + V +C GY + C NG+W P C C P + + +R + +++ Y C GY + + + + C K C+ C P NG++ SD T V Y C Y+L P + C NG W+ ++P C
Sbjct: 2650 GESMPTCQIISCGELPTPPSGHRIGTMSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRICQQDHHWSGKTPFCVPIT--CGH----PGNPVNGLTQGSQFNLNDVVKFICNPGYIAEGAARSQCLAS---GQWSDTLPTCRIINCTDPGHQENSVRQVHTSGPHRFSFGTTVSYQCNHGFYLLGTP--------ALSCQGDGTWDRPRPQCLLVSCGHPGSPPHAQMSGDSYIVGAVVRYSCTGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHGIRLGDSFAPGSVMRFSCDAGHVLRGSSERM-CQANGSWSG----SQPECGVISCGNPGTPSNARV-----------VFSDGLVFSSSVVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGD--PGIPANGIRLGNDFRYNKTVTYQCVPGYVMESHR--------VSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVV---GSDFT----------WGSSVSYACLEGYQLSLPAVLTCEGNGSWT-GELPQC 3189 HSP 7 Score: 65.4698 bits (158), Expect = 2.417e-10 Identity = 46/190 (24.21%), Postives = 76/190 (40.00%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI 965
C P P G V ++C + L G +R+CQ++ SG++P C D T + P +P + ++S ++ G V CQ GY + C N W P C C + E P + + + I C +GF ++ ++ R C+ADG W+G +C +
Sbjct: 3194 CGDPGVPPRGRREDRGFSYRSSVSFSCHAPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGMPQFGIQNSSQ--GYQVGSTVLFRCQKGYL--LQGSTTRTCLPNLTWSGTPPDCVPHHCKQPETPTHANVGALDLPSMGYTLIYSCQEGFSLRGGSEH-------RTCKADGSWTGKPPVCLEV 3372
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Match: Csmd3 (CUB and Sushi multiple domains 3 [Source:MGI Symbol;Acc:MGI:2386403]) HSP 1 Score: 107.457 bits (267), Expect = 2.474e-23 Identity = 90/310 (29.03%), Postives = 123/310 (39.68%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYA--LKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P P NG +VG V Y C+ GY L G R R C N SG P C T C + P I ++ +F G + IC GYE + + + NG W + +C K CG P G+ ++ YQS CN F + ++ R CQ DG WSG + C T C P +G + V S+ F CK+G+ L GS R C + W G CI +C P A V + +HG Y C+ L G T C + +G +P
Sbjct: 2261 ISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVT--CSTPPQISNGRLEGT----NFDWGFSISYICSAGYELSFPAVLTCVGNGT-WSGEVPQCLPKFCGDPGIPSQGKRE-GKSFIYQSEVSFSCNSPFILVGSS--------TRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVP 2554 HSP 2 Score: 102.834 bits (255), Expect = 6.031e-22 Identity = 115/443 (25.96%), Postives = 159/443 (35.89%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGY--ELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P+ G + + D V ++C GY ++GP K CQAN + S P C + C S P IP ++ +F G V C GY S +I + NG +W +C CG P N + YT+ S CT + R CQ +G WSG C T C + P +G S F C GY L+GS R C G+W G C CG P KV + TT + Y C L G S C SG LP +C + D+ G +V C GY ELN + C NG+W+ +P C CS PP + + + Y C GY ++
Sbjct: 1944 VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVC--KVVNC-SDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG-QWDKPLPECIMIDCGHPGIPPNA-VLSGEKYTFGSTV--------HYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGP-SVRQCTANGTWSGSLP--------NCTIISCGDPGI------PANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCST-PPQISNGRLEGTNFDWGFSISYICSAGYELSF 2357 HSP 3 Score: 95.1301 bits (235), Expect = 1.485e-19 Identity = 145/600 (24.17%), Postives = 218/600 (36.33%), Query Frame = 3
Query: 228 KPECHVKSLDNVKHLPNGC-----PSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGR---TMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC---IVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTL--IGETSFLTCGE-----VDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVRFLS-LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
+P C + S + PNG S TA C + + + C+ G + C P VNG D V Y C G+ L G R CQ + SG P C + C P + ++ ++ + F + V C GY + P K A+C N +W + P C+ +C P N + + + N+TY ++ CN G+ F + CQ +G+W C I C P N + G T S + C L G R C G+W GS C CG P HG++ E +++ST+ +T ++ G + N S +PE K + P + KV+ D T + V C GY L+ + C NG+W+ +P C +C P + + +R+ Y C GY I L + T +T G W+ MPT C+ C+ PP NG RL + + Y C Y L P + C+ NG WS ++P C
Sbjct: 1841 RPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGH----PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK----AQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGY--------FLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDP----------GTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVF-----------RIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGD--PGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTT-------NGTWSGVMPT--CRAVTCSTPPQISNG-----------RLEGTNFD--WGFSISYICSAGYELSFPAVLTCVGNGTWS-GEVPQC 2376 HSP 4 Score: 94.3597 bits (233), Expect = 3.108e-19 Identity = 136/546 (24.91%), Postives = 191/546 (34.98%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQ----VEYTCKSGYALKGPRKRYCQANL----RLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKY--DPIKCEKKSCGKLE----DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT--AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPP----SMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXN----GEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQ 1925
G I C P P +G+ I G Q V + C G+ L G C+ + P C Q C IP + D+ G V C +GY K A C + W +C +C + D R + ++Y Y++ + C+ G+ +C +G WS T C I C EL P NG +G + S F C G+ L GS +R+C G W GS + C+ +CG P IV +V E + Y+C LIG +S C + N SG LP C P I+ F +D VT CN GY + C N W+ P + + P S + S + + + ++ Y C+ GY++ S++ + N G W K P C C P P N GE Y G + V Y C L G C LNGHWS Q
Sbjct: 1649 GFRIRYIAFYCSTPESPPHGYI---ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPAC--QAISC----GIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLDHGRWRIVNGSHYEYKTKVVFSCDPGYH--------GLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIG-SSVRICQQDHNWSGQLPS--------CVPVSCGHPGSPIYGRTSGNGFNFNDVVTF------SCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF--------GSSVLICQPN-GQWDK-PLPECIMIDCGHPGIPPNAVLSGEKYTFGST-----------------VHYSCTGKRSLLGQASRTCQLNGHWSGSQ 2135 HSP 5 Score: 90.8929 bits (224), Expect = 3.491e-18 Identity = 117/461 (25.38%), Postives = 162/461 (35.14%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANH-SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI--VRNCGPPPEIVFAKVAYEATTHGAQ----AEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLH-CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDI--------------LPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYY-IALRKDGMETLSTIFDIKCNKGNWT 1703
+QC P NG V Y+C GY L GP R C AN SGS P CT + P IP + DDF G++V +CQ GY + C N W C +C NGR + N+ + C+ G+++ C +G WSG+ C C + P G+ G S +F C + L GS R C +G W GS+ CI R P + + + T G Q ++ CK L G T+ TC SG +P+C+ H CK E+ N + D +HG + C G+ L +P C GS + A + P LS+ D A+ Y G Y RK M T F+ + N T
Sbjct: 2202 VQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTI---ISCGDPGIPANGLRYG---DDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGR-LEGTNFDWGFSISYICSAGYELSFPA--------VLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGV--PRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTT-RTCLPDLTWSGI----QPECIPHSCKQ----------PESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPK---------LSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT 2621 HSP 6 Score: 88.5817 bits (218), Expect = 1.987e-17 Identity = 126/522 (24.14%), Postives = 185/522 (35.44%), Query Frame = 3
Query: 462 QVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIV----FAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCV--EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDE--LPISWLYYRSD 1991
+V ++C GY GP C N S Q C P P + N G C G+ + +C + W +C CG E NG+ + NY Y+ + CN GF++ ++ R CQ D WSG C + C P G G N + TF C GY + G +C W C V NC P +K+ + T+G Y C L G +S L C +G KP P+C++ +D I N + ++ T G+ V C L C NG W+ P C P + + + + + S R+ C GY + G E + + + G+WT E C+ +C P T NG+++ + D T + I Y C Y L GP + C NG WS +P C I + +P + L Y D
Sbjct: 1810 KVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPP----NGNKIGTQTSYGSTAIFTCDLGFM--LVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVI-GENYGYRDTVVYQCNPGFRLIGSS--------VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG-SSVLIC----QPNGQWDKPLPECIM------IDCGHPGIPPNA----VLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILY----GSEERTCL-----SNGSWTGRQPE-CKAVQCGNPGTTANGKVFRI---DGTTFSSSVI---------YSCLEGYILSGPSVRQCTANGTWS-GSLPNCTIISCGDPGIPANGLRYGDD 2278 HSP 7 Score: 58.5362 bits (140), Expect = 2.765e-8 Identity = 52/226 (23.01%), Postives = 87/226 (38.50%), Query Frame = 3
Query: 288 SKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
S C+A + + + CV + G V + C P P G + +V ++C S + L G R CQ + SGS P C + T P +P +N+ F+ G V+ C+ G+ + C + W +C SC + E P + + + ++ I C GF + T+ R C++D W+G +C A
Sbjct: 2346 SYICSAGYE--LSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTF--GFQVGSVVQFHCKKGHL--LQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEH-------RVCRSDNTWTGKVPVCEA 2558 HSP 8 Score: 57.3806 bits (137), Expect = 7.930e-8 Identity = 65/272 (23.90%), Postives = 102/272 (37.50%), Query Frame = 3
Query: 333 RAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQ-SIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLH-GSHLRKCTREGNWDGSNSTC 1130
R + C + G++ + C P Q NG + G + Y C +GY L P C N SG P+C + C P IP + + F +V C + + S + + +G P I+ + SC P++G NN + +Q +QF C G +Q +T R C D WSG C C + P + V+G+ + + C+ G+ L G+ R C + W G C
Sbjct: 2301 RVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPK--FC-GDPGIPSQGKREGKS---FIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQGST--------TRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVC 2556
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Match: sp|Q22328|LEV9_CAEEL (Protein lev-9 OS=Caenorhabditis elegans OX=6239 GN=lev-9 PE=1 SV=3) HSP 1 Score: 192.971 bits (489), Expect = 9.435e-52 Identity = 169/578 (29.24%), Postives = 241/578 (41.70%), Query Frame = 3
Query: 291 KACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHS-ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSN-RDDFKNGEDVKIICQNGYED-PYKSHIIAKC-----NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXX----XXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
K C A+ DC R + C+CD CGL C+ C P NG + L G EY C GY L G +R CQAN S S+P C Q C P IP+ VHD S+ ++ +V C GY K I+KC N +W ++C+ ++C D +NG + + Y CN GF + +T RQC ++G+W+ + A C A C S P +G+V+G T S+ T+ C GY+L G R C EG W G+ C C P + + T+ GA A ++C T G S C E G P P+CL C+ + + K+ + + G+ V +CN +E N D C N +W+ +P C +C PP + ++ + F H S+A+Y C+ GY+ R + + IKC G WTK P C P T G+I L G K R + ++C L GP A C+NG W P P C H + L+ R
Sbjct: 33 KECIADEDC----KRNKRCMCDGE-CGLSCVNPIAMCHPLPNIENGFIRTAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCRLQLK-CGPPPEIPFA-VHDGSSFSGEYDLDAEVAYNCIPGYHKFNAKGLSISKCLLNRKNVAQWFGPDLRCKARACPDPGDIENG-LREGDTFEYPHHVKYSCNPGFLLVGSTS--------RQCSSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFGAVAVFRCLETMTHEG-ASKAKCME----DGQWSAPIPRCLASCRVPHIQNGKIRDKSEGQL--------IASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYH-PNRNNQI--------IKCLYGEWTKDGPPMKCLPSWCEHPSKTYGTLPGGQILLEGILGAYEFQSYIQKVEEGRAISFQCGKGNYLIGPPKATCVNGEWMPKVSPKCVSQTHPMIEGKILWDR 572
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Match: sp|P0C6B8|SVEP1_RAT (Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Svep1 PE=1 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 2.334e-31 Identity = 152/565 (26.90%), Postives = 226/565 (40.00%), Query Frame = 3
Query: 288 SKACTANIDCWVEYDRAQLCVC----DSYLC---------GLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPE----PKCLLH-CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIP---RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW 1913
S +C +C V D ++ C SY+C G C E ++C+ P P NGH+ I VG +V ++C+ G+ L G RK C + P C + AP +P D S F G V+ C GY +G+ W + CE C + E+ NG+ + + TY SIA C DG+ +Q + +C A G W C + C E ++ G T ++ T+ CKEGY L G C G W+ SN C+ +C PP + A G A Y C +L + S L C N W+P PE P+C+ H C+ + S I E+ F G+ V KC G+ LN+ C G W+ P +C+ C PPS+ + ++ Y CH G+YI K + G W++ P C P C +PP +NG +L + RT ++ +++C+P Y+ G + VC N HW
Sbjct: 1735 SPSCLDVDECAVGSDCSEHASCLNTNGSYICSCKPPYTGDGKNCAE-PVKCKAPENPENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESGEWDHLRPSC---EAISCGAPPVPENGGVDGSA---FTYGSKVRYRCDKGYTLAGDEESACLASGS-WSHSSPVCELVKCSQPENINNGKYIL-SGLTYLSIASYSCEDGYSLQGPS--------LIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTGSNFTFGNMVTYTCKEGYTLAGPDTIICQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSL-ADNSQLICNAQGN---WVP-PEGQAVPRCIAHFCE--KPPSVSYSILESVSKAKFAA------GSVVSFKCMEGFVLNTSAKIECLRGGQWSPSPLSVQCIPVRC-GEPPSITNGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEAT---------GQWSR-PLPTCHPVSCNEPPKVENG--FLEHTTGRTFESE----------ARFQCNPGYKAVGSPVFVCQANRHW 2246 HSP 2 Score: 124.79 bits (312), Expect = 6.727e-28 Identity = 152/573 (26.53%), Postives = 229/573 (39.97%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTD-------------LCFSAPYI-----PYTQVHDN-----------------SNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-----NFIPRCVEAACSARPPSMKYSTVRFLS---LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGN-WTKMP-TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++C P NG + L G V Y C SGY L G + +C N +G P C D + L + YI PYT N S + G +V C+ G++ I +G EW + CE SCG P+NG + + +TY S C+ G+ + + C A G WS + +C + C + NG+ + T SI ++ C++GY L G L +CT G+WD + +C + +CG PP + A T G Y CK TL G + + +G +CL + C +P VD H + +T + + D + C GY L + C G+W +PRC+ C +PPS+ YS + +S S+ + C G+ L+T I+C +G W+ P + C P +C +PP+ NG Y G T+ S VV Y CH + +KG K + C G WS P +PTC + +E P
Sbjct: 1683 IRCGLPPTLENGFYSAEDLHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYICSCKPPYTGDGKNCAEPVKCKAPENPENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESG-EWDHLRPSCEAISCGAPPVPENG-GVDGSAFTYGSKVRYRCDKGYTLAGDEES--------ACLASGSWSHSSPVCELVKCSQPENINNGKYILSGLTYLSIASYSCEDGYSLQGPSLIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTGSNFTFGNMVTYTCKEGYTLAGPDTIIC-----QANGKWNSSNHQCLAVSCDEPPNVD------HASPETAHRLFGDTAFY------YCADGYSLADNSQLICNAQGNWVPPEGQAVPRCIAHFCE-KPPSVSYSILESVSKAKFAAGSVVSFKCMEGF----------VLNTSAKIECLRGGQWSPSPLSVQCIPVRCGEPPSITNG--YPSG-------TNYSF----GAVVAYSCHKGFYIKGEKKSTCEATGQWSRP-LPTCHPVSCNEPP 2203 HSP 3 Score: 117.472 bits (293), Expect = 1.196e-25 Identity = 131/511 (25.64%), Postives = 200/511 (39.14%), Query Frame = 3
Query: 441 SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTD-QTDLCFSAP--YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAE--YKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCEFI 1946
S L G V Y C+ GY L G CQ + +G+ P C + DL + ++ +TQ G + C+ G+ SH+ +W +CE SC + NG ++ N+Y+Y + C+ G+ + T +R CQ + +W G +C + C P NG+V G T + C EG+ L G+ R C G+W G+ +C+ C PP++ A + +G + E + C L G T LTC +P CKP +F HG H++ +C GY+L+ + C +GSW+ P C+ CS P ++ TV L + C G+ L + +I C+ G W+ P C+ C PT NG I + G P + VV Y C P Y ++G +C G WS P PTCE +
Sbjct: 2667 SQFLYGTTVSYRCEPGYELLGIPVLVCQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQT---------TMGSAAQYSCKPGHVL-EGSHLRLCLQNKQWSGTVPRCEVISCSEPNPLGNG-SIKGNDYSYLGVLHYECDSGYVLNGTE--------KRTCQENKQWDGHEPVCLPVDCGSPPVPTNGQVTGEEYTFQKEIAYSCGEGFILEGARSRVCLTNGSWSGTTPSCVPVRCPAPPQV--ANGVTDGLDYGFKKEVTFHCLEGYVLQG-TPKLTCQSNGTWDAEVPI--------CKPATCGPPADLPQGFPNGFSFF------HGGHIQYQCFTGYKLHGNPSRRCLPDGSWSGSTPSCLPCTCST--PIIQQGTVNATDLGCGKTVQIECFKGF----------KLLGLPEITCDANGQWSDFPL--CEHADCGPLPTVPNG-IVIKG------------SPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWSEP-YPTCEPV 3113 HSP 4 Score: 113.62 bits (283), Expect = 2.120e-24 Identity = 111/431 (25.75%), Postives = 164/431 (38.05%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFD 1676
I ++C PV P NG + + +G +Y+CK G+ L+G R C N + SG+ P C + C + + N D+ + C +GY + N ++P+ C CG P NG+ + YT+Q C +GF ++ R C +G WSG T C + CP NG G+ TF C EGY L G+ C G WD C CGPP ++ + HG +Y+C + L G S C + SG P C P + + N T ++ G V+ +C G++L C NG W+ P C A C P++ V S D++ Y C GY I D + T I+
Sbjct: 2707 ISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHVLEGSHLRLCLQNKQWSGTVPRC--EVISCSEPNPLGNGSIKGN----DYSYLGVLHYECDSGYVLNGTEKRTCQENKQWDGHEPV-CLPVDCGSPPVPTNGQ-VTGEEYTFQKEIAYSCGEGFILEGARS--------RVCLTNGSWSGTTPSCVPVRCPAPPQVANGVTDGLDYGFKKEVTFHCLEGYVLQGTPKLTCQSNGTWDAEVPICKPATCGPPADLPQGFPNGFSFFHGGHIQYQCFTGYKLHGNPS-RRCLPDGSWSGSTPS--------CLPCTCSTPIIQQGTVNAT-------DLGCGKTVQIECFKGFKLLGLPEITCDANGQWSDFPLCEHADCGPL-PTVPNGIVIKGSPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWS 3104 HSP 5 Score: 105.531 bits (262), Expect = 6.622e-22 Identity = 128/523 (24.47%), Postives = 204/523 (39.01%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYD-PIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD-TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH-GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDE-VTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C G+ +KG +K C+A + S P C + C P + + + R F++ + + C GY+ + + N W D P+ C +CGK +NG + ++ S CN+G+++ + CQ GKWS + C C E EN V+ + + T CKEG+ L G + KC G W+GS C + C PP I F A H G+ +Y C L G L +VD G P P+C+ V + + N I+H + + + + C G+EL + C NG W P C C P + +S ++ Y C G+ R +G ++L+ + GNW M C C+ P +NG ++ G R + ++ Y C P +++ G + C WS PTC
Sbjct: 2137 IPVRCGEPPSITNGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSRPLPTCHPVS--CNEPPKVENGFLEHTTGRT-FES--EARFQCNPGYKAVGSPVFVCQAN-RHWHSDAPLSCTPLNCGKPPPIQNG-FLRGESFEVGSKVQFVCNEGYELV--------GDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELTSEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPVCKLVLCQSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGNPIILC--QVD---GTWSSPLPECV-----------PVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNTTTLCGENGQWLGGKPMCRPIEC-PEPKEILNGQFSSVSFQYGQTITYSCDRGF----RLEGPKSLTCL-----ETGNW-DMDAPSCNAIHCSDPQPIENG--FVEGADYR-----------YGAMIIYSCFPGFQVVGHAMQTCEETGWS-SSSPTC 2603 HSP 6 Score: 100.523 bits (249), Expect = 2.811e-20 Identity = 130/571 (22.77%), Postives = 207/571 (36.25%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTY-QSIAIQF-CNDGFK-------------------------------IQCTTDQFEDKNCRRQ------------------CQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAAC----SARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWS 1916
VC+ +D C P P NG ++ Y+C G+ L+G R R C N SG+ P C C + P + + ++ D+ ++V C GY + + NG W + C+ +CG D G + N +++ IQ+ C G+K IQ T D C + C A+G+WS D +C C L NG V+ + +++ T+ C+ GY + GS CT +G W TC +CGPPP + A EA T+ ++ + +C + +T TC + D + W P+ ++C P K +N+T + D+ V C G+ + C +G+W P E +C +P S ++ V S Y C GY + ++ + C + C+ +C P NG+ L + L + CH Y L+GP A C NG WS
Sbjct: 2821 VCLPVD--CGSPPVPTNGQVTGEEYTFQKEIAYSCGEGFILEGARSRVCLTNGSWSGTTPSCVPVR--CPAPPQV----ANGVTDGLDYGFKKEVTFHCLEGYVLQGTPKLTCQSNGT-WDAEVPICKPATCGPPADLPQG---FPNGFSFFHGGHIQYQCFTGYKLHGNPSRRCLPDGSWSGSTPSCLPCTCSTPIIQQGTVNATDLGCGKTVQIECFKGFKLLGLPEITCDANGQWS-DFPLCEHADCGPLPTVPNGIVIKGSPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWSEPYPTCEPVSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVVDTDTDTFTC-QQDGR--WFPE-----RINCSP------KTCPVPSNRTRIRVHGDDFQVNRQVSVSCTEGFTYDGADRSTCQPDGTWE--PPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERV----------CQENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLL-------------FSCHRGYTLEGPPEAHCTANGTWS 3339 HSP 7 Score: 100.138 bits (248), Expect = 3.670e-20 Identity = 103/421 (24.47%), Postives = 160/421 (38.00%), Query Frame = 3
Query: 474 TCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGET---------------------------SFLTCGEVDNKSGWLPKPE-----PKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
+CK G+AL+GP C + + +GS P C + LC S P IP+ V +S F G VK +C +G+ I+ + +G W +C C + E+ NG ++ Y S + C GF++ T C +G+W G +C I CPE NG+ V T+ C G++L G C GNWD +C +C P I V +GA Y C ++G F C V + G+ + + P H + + + I E + + H + +GT V +C GYEL + C +G+WN P C+ C P + + + F S A+Y C G+ +
Sbjct: 2343 SCKEGHALQGPSVLKCLPSGQWNGSFPVC--KLVLCQSPPLIPF-GVPASSGALHF--GSTVKYLCVDGFFLRGNPIILCQVDGT-WSSPLPECVPVECPQPEEILNG-IIHVQGLAYLSTTLYTCKPGFELVGNTTTL--------CGENGQWLGGKPMCRPIECPEPKEILNGQFSSVSFQYGQTITYSCDRGFRLEGPKSLTCLETGNWDMDAPSCNAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVVGHAMQTCEETGWSSSSPTCVPIDCGLPPHIDFGDCTRVSDGQGYFVQEDDMMEVPYLTPHPQHLEATAKASEITEE----SLVPHASQFLYGTTVSYRCEPGYELLGIPVLVCQEDGTWNGTAPSCISIECDL-PVAPENGFLHFTQTTMGSAAQYSCKPGHVL 2743 HSP 8 Score: 97.4413 bits (241), Expect = 2.175e-19 Identity = 136/576 (23.61%), Postives = 215/576 (37.33%), Query Frame = 3
Query: 450 LVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQ--TDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEV-MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNS-TCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYST-VRFLSLKHDSLARYYCHFGYY------IALRKDGM-----------------ETLSTIFDIKCNKGNWTKMPT--EGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTD------------KSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI-MHDELPISWLYYRSDDKK*EDYVFYLHF 2030
L GD Y C GY+L + C A E + + C P + Y+ + ++ ++ F G V C G+ S I G +W P ++C CG+ NG NY++ ++ C+ GF I+ + C+A G+WS C + C E ENG + T S F+C GY+ GS + C +W +C NCG PP I + E+ G++ ++ C L+G+ S+ TC KSG W KP PKC+ A+ + EN ++ + + + C G+ L + C +G WN P C C + PP + + +L S +Y C G++ I + DG E L+ I ++ T + T G + T +NG+ LG R + S+ + + + Y C +RL+GPK CL G+W P+C I D PI + D + + Y F
Sbjct: 2033 LFGDTAFYYCADGYSLADNSQLICNAQGNWVPPEGQAVPRCIAHFCEKPPSVSYS-ILESVSKAKFAAGSVVSFKCMEGFVL-NTSAKIECLRGGQWSPSPLSVQCIPVRCGEPPSITNGYPS-GTNYSFGAVVAYSCHKGFYIK--------GEKKSTCEATGQWSRPLPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAVGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLRGESFEVGSKVQFVCNEGYELVGDNSW-TC----QKSGKWSKKPSPKCV------PTKCAEPPLLENQ----LVLKELTSEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPVCKLVLCQS-PPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGNPIILCQVDGTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNTTTLCGENGQ--WLGGKPMCRPIECPEPKEILNGQFSSVSFQYGQTITYSCDRGFRLEGPKSLTCLETGNWD-MDAPSCNAIHCSDPQPIENGFVEGADYRYGAMIIYSCF 2578 HSP 9 Score: 90.8929 bits (224), Expect = 2.314e-17 Identity = 114/471 (24.20%), Postives = 175/471 (37.15%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEYDRA---QLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG--ETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+V S VK L + CP + N+ W ++ ++ V S + C ++ P ++P +G G +V C G+ + G +YC + S P C + C +P T + + +D G V C +GY S + NG+ P + C D + N N +Y C +C+ DGK + C A PE PENG +G +V + TF C+EG+QL G C G WD +C +CG PP V A T+G++ Y+C TL G E++ L G + S P C L K EN +I+ +T+ + C GY L L C +GSW+ P + PP +K + + ++ Y C GY +A
Sbjct: 1577 YVLSPQQVKSLASSCPEELSRGNVLAWPDFVSGITGKVKVDSSSIFCSDCPSLEGSV-PHLRPASGDRKP-----GSKVSLFCDPGFQMVGNPVQYCLNQGQWSQPLPHC--ERIRCG----LPPTLENGFYSAEDLHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSY------IC----------------SCKPPYTGDGKNCAEPVKCKA---PEN--PENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESGEWDHLRPSCEAISCGAPPVPENGGVDGSAFTYGSKVRYRCDKGYTLAGDEESACLASGSWSHSS-------PVCEL---------VKCSQPENINNGKYILSG-LTYLSIASYSCEDGYSLQGPSLIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTGSNFTFGNMVTYTCKEGYTLA 1991 HSP 10 Score: 82.8037 bits (203), Expect = 8.324e-15 Identity = 98/423 (23.17%), Postives = 156/423 (36.88%), Query Frame = 3
Query: 465 VEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG-ETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI--ALRKDGMETLSTIFDIKCNKGNWTKMP 1712
V Y+C+ GY ++G C S P C + C P + ++ + K VK+ C GY + W + I C K+C + R ++ + +++ C +GF D R CQ DG W + C ++C + PE+G V+G + S ++C GY+L G+ R C W G + C C P E K E TT G + C TL G + T + L KP P C + PF I EN + E +V KC G+ L + + C + +W RC + +C P ++ + R + ++ + + C+ GY + +LR +E G WT P
Sbjct: 3079 VTYSCRPGYIIQGSSDLICTEKGIWSEPYPTCEPVS--CGPPPTVANAVATGEAHTYESK----VKLRCLEGYVVDTDTDTFTCQQDGRWFPERINCSPKTCPVPSNRTRIRVHGDDFQVNRQVSVS-CTEGFTY--------DGADRSTCQPDGTWEPPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTANGTWSHLAPLCKPNP-CPV---PF-------VIPEN----ALLSEREFYVNQNVSIKCREGFLLKGNGIITCNPDETWTQTNARCEKISCGP-PTHVENAIARGVHYQYGDMVTFSCYSGYMLEGSLRSVCLE-----------NGTWTPPP 3459 HSP 11 Score: 74.7146 bits (182), Expect = 2.342e-12 Identity = 68/244 (27.87%), Postives = 96/244 (39.34%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-KLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNW 1109
I + C P P +G S G V Y C GY L+G R+R CQ N + SG C + C + P + + ++ +G + C GY E P ++H A NG W + C+ C P+N Y Q+++I+ C +GF ++ N C D W+ A C I C + EN GV + TF C GY L GS C G W
Sbjct: 3230 IPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQENRQWSGRVAVCRESR--CEAPAEFP----NGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTA--NGT-WSHLAPLCKPNPCPVPFVIPENALLSEREFYVNQNVSIK-CREGFLLK--------GNGIITCNPDETWTQTNARCEKISCGPPTHVENAIARGVHYQYGDMVTFSCYSGYMLEGSLRSVCLENGTW 3455 HSP 12 Score: 58.5362 bits (140), Expect = 2.164e-7 Identity = 57/216 (26.39%), Postives = 95/216 (43.98%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI 965
+E +R ++C + G V + + +C+ P + NG A G + ++C GY L+GP + +C AN S P C + + C IP + S R+ + N ++V I C+ G+ K + I CN +E W +CEK SCG +N +Y Y + C G+ ++ + R C +G W+ IC A+
Sbjct: 3266 LEGNRERVCQENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTANGTWSHLAPLC--KPNPCPVPFVIPENALL--SEREFYVN-QNVSIKCREGFL--LKGNGIITCNPDETWTQTNARCEKISCGPPTHVENA-IARGVHYQYGDMVTFSCYSGYMLE--------GSLRSVCLENGTWT-PPPICRAV 3464
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Match: sp|A2AVA0|SVEP1_MOUSE (Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Mus musculus OX=10090 GN=Svep1 PE=1 SV=1) HSP 1 Score: 131.724 bits (330), Expect = 4.872e-30 Identity = 136/516 (26.36%), Postives = 202/516 (39.15%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP---KPEPKCLLH-CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIP---RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHW 1913
++C+ P P NGH++ I VG V ++C G+ L G C P C + P +P D S F G V C GY +G+ W + CE C + ED NG+ + + TY SIA C +G+ +Q + +C A G W C + C E ++ + G T + + CKEGY L G C G W+ SN C+ +C PP + A G A Y C +L + S L C N W+P + P+C+ H C+ + S I E+ F G+ V KC G+ LN+ C G W+ P +C+ C PPS+ + ++ Y CH G+YI K + G W+K PT C P C +PP +NG +L + RT ++ +++C+P Y+ G + VC N HW
Sbjct: 1786 VKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSC---EAISCGVPPVPENGGVDGSA---FTYGSKVVYRCDKGYTLSGDEESACLASGS-WSHSSPVCELVKCSQPEDINNGKYIL-SGLTYLSIASYSCENGYSLQGPS--------LLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSL-ADNSQLICNAQGN---WVPPAGQAVPRCIAHFCE--KPPSVSYSILESVSKAKFAA------GSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRC-GEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEAT---------GQWSK-PTPTCHPVSCNEPPKVENG--FLEHTTGRTFESE----------ARFQCNPGYKAAGSPVFVCQANRHW 2250 HSP 2 Score: 126.716 bits (317), Expect = 1.763e-28 Identity = 154/573 (26.88%), Postives = 229/573 (39.97%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTD-------------LCFSAPYI-----PYTQVHDN-----------------SNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-----NFIPRCVEAACSARPPSMKYSTVRFLS---LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGN-WTKMP-TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
++C P NG + G V Y C SGY L G + +C N +G P C D + L + Y+ PYT N S+ + + G V C G+E S I G EW CE SCG P+NG + + +TY S + C+ G+ + + D+ C A G WS + +C + C + NG+ + T SI ++ C+ GY L G L +CT G+WD + +C + +CG PP + A + T G Y CK TL G + V +G +CL + C +P VD H + +T + + D + C GY L + C G+W +PRC+ C +PPS+ YS + +S S+ + C G+ L+T I+C +G W+ P + C P +C +PP+ NG Y G T+ S VV Y CH + +KG K + C G WS P PTC + +E P
Sbjct: 1687 IRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETG-EWDRLRPSCEAISCGVPPVPENG-GVDGSAFTYGSKVVYRCDKGYTL--SGDE------ESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTI-----VCQANGKWNSSNHQCLAVSCDEPPNVD------HASPETAHRLFGDTAFY------YCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCE-KPPSVSYSILESVSKAKFAAGSVVSFKCMEGF----------VLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANG--YPSG-------TNYSF----GAVVAYSCHKGFYIKGEKKSTCEATGQWSKP-TPTCHPVSCNEPP 2207 HSP 3 Score: 118.242 bits (295), Expect = 8.015e-26 Identity = 115/434 (26.50%), Postives = 170/434 (39.17%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE--NGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFD 1676
I ++C PV P NG + + +G +Y+CK G+ L+G R C N + SG+ P C + C P + + DD+ + C +GY C N +W C CG P NGR + YT+Q C +GF ++ R C +G WSG T C + CP +PP+ NG G+ F C EGY L G+ C G WD C CGPP ++ + HG +Y+C + L G S C + SG P C P + + + N T ++ G V+ +C G++L C NG W+ +P C A C P++ + V SL D++ Y C GY + D + T I+
Sbjct: 2710 ISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRC--EAISCSK----PNPLWNGSIKGDDYSYLGVLYYECDSGYI--LNGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGR-VKGEEYTFQKEITYSCREGFILEGARS--------RICLTNGSWSGATPSCMPVRCP--APPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPS-RRCLPNGSWSGSSPS--------CLPCRCSTPIIQQGTINAT-------DLGCGKTVQIECFKGFKLLGLSEITCDANGQWSDVPLCEHAQCGPL-PTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWS 3107 HSP 4 Score: 111.694 bits (278), Expect = 8.125e-24 Identity = 127/511 (24.85%), Postives = 197/511 (38.55%), Query Frame = 3
Query: 429 HANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTD-QTDLCFSAP--YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCE 1940
HA+H L G V Y+C+ GY L G CQ + +G+ P C + DL + ++ +TQ G + C+ G+ SH+ +W +CE SC K NG ++ ++Y+Y + C+ G+ + + + +R CQ + W G +C + C P NG V G T T+ C+EG+ L G+ R C G+W G+ +C+ C PP++ + + C L G LTC +P CKP + F HG H++ +C GY+L+ + C NGSW+ P C+ CS P ++ T+ L + C G+ L + +I C+ G W+ +P C+ +C PT N I L G + VV Y C P Y ++G +C WS P PTCE
Sbjct: 2668 HASH--FLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQT---------TMGSAAQYSCKPGHIL-EGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNG-SIKGDDYSYLGVLYYECDSGYIL--------NGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPR-LTCQSNGTWDAEVPV--------CKPATCGPPA------DLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCST--PIIQQGTINATDLGCGKTVQIECFKGF----------KLLGLSEITCDANGQWSDVPL--CEHAQCGPLPTIPNA-IVLEGSLSE------------DNVVTYSCRPGYTMQGSSDLICTEKAIWSQP-YPTCE 3114 HSP 5 Score: 106.686 bits (265), Expect = 2.892e-22 Identity = 126/523 (24.09%), Postives = 204/523 (39.01%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYD-PIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD-TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTH-GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDE-VTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P NG+ + + G V Y+C G+ +KG +K C+A + S P C + C P + + + R F++ + + C GY+ + + N W D P+ C +CGK +NG + ++ S CN+G+++ + CQ GKWS + C C E EN V+ + + T CKEG+ L G + KC G W+GS C + C PP I F A H G+ +Y C L G + L S W P P+C+ V + + N I+H + + + + C G+EL + C NG W P C C P + +S ++ Y+C G+ R +G ++L+ + G+W P C C+ P +NG ++ G R + ++ Y C P +++ G + C WS PTC
Sbjct: 2141 IPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVS--CNEPPKVENGFLEHTTGRT-FES--EARFQCNPGYKAAGSPVFVCQAN-RHWHSDAPLSCTPLNCGKPPPIQNG-FLKGESFEVGSKVQFVCNEGYELV--------GDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGSPTIL----CQADSTW-SSPLPECV-----------PVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIEC-PEPKEILNGQFSSVSFQYGQTITYFCDRGF----RLEGPKSLTCL-----ETGDWDMDPPS-CDAIHCSDPQPIENG--FVEGADYR-----------YGAMIIYSCFPGFQVLGHAMQTCEESGWS-SSSPTC 2607 HSP 6 Score: 96.6709 bits (239), Expect = 4.288e-19 Identity = 107/422 (25.36%), Postives = 160/422 (37.91%), Query Frame = 3
Query: 474 TCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCK-PFQVD--------------------------------SAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
+CK G+AL+GP C + + +GS P C + LC S P IP+ V +S F G VK +C +G+ I+ + + + W +C C + E+ NG ++ Y S + C GF++ N C +G+W G +C I CPE NG+ V T+ C G++L G C G+WD +C +C P I V +GA Y C ++G + TC E SGW P C+ + C P +D A EN K + +GT V C GYEL + C +G+WN P C+ C P + + + F S A+Y C G+ +
Sbjct: 2347 SCKEGHALQGPSVLKCLPSGQWNGSFPIC--KMVLCPSPPLIPF-GVPASSGALHF--GSTVKYLCVDGFFLRGSPTILCQAD-STWSSPLPECVPVECPQPEEILNG-IIHVQGLAYLSTTLYTCKPGFELV--------GNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVSFQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGH-AMQTCEE----SGW-SSSSPTCVPIDCGLPPHIDFGDCTKVRDGQGHFDQEDDMMEVPYLAHPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDL-PVAPENGFLHFTQTTMGSAAQYSCKPGHIL 2746 HSP 7 Score: 91.6633 bits (226), Expect = 1.534e-17 Identity = 85/359 (23.68%), Postives = 135/359 (37.60%), Query Frame = 3
Query: 381 MEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYT-YQSIAIQF-CNDGFK-------------------------------IQCTTDQFEDKNCRRQ------------------CQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPK 1304
M I + C P P NG ++ Y+C+ G+ L+G R R C N SG+ P C C + P +P + ++ D+ ++V C GY + + NG W + C+ +CG D G + N ++ Y IQ+ C G+K IQ T D C + C A+G+WS D +C C L N V+ + +++ T+ C+ GY + GS CT + W TC +CGPPP + A EA T+ ++ + +C + +T TC W+P+
Sbjct: 2824 MCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVR--CPAPPQVP----NGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGT-WDAEVPVCKPATCGPPADLPQG---FPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWS-DVPLCEHAQCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDSDTDTFTC---QQDGHWVPE 3168 HSP 8 Score: 87.0409 bits (214), Expect = 3.433e-16 Identity = 132/563 (23.45%), Postives = 207/563 (36.77%), Query Frame = 3
Query: 324 EYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKII----CQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNW----DGSNSTCIVRNCGPPPEI---VFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLK-HDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELPI 1967
E+DR + C++ CG+ PPV P NG + S G +V Y C GY L G + C A+ S S P C + +Q D +N +G I C+NGY S + +G+ W P C+ SCG+ K+ + +N+T+ + C +G+ + CQA+GKW+ C A+ C E ++ + C +GY L + C +GNW + CI C PP + + V+ G+ +KC L E W P P + C P + + TN+ + G V C+ G+ + + C G W+ P C +C+ PP ++ + + + +S AR+ C+ GY A S +F + N+ +W C P C KPP +NG +L G+S V++ C+ Y L G C +G WS P C E P+
Sbjct: 1833 EWDRLRP-SCEAISCGV----------PPV-PENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCE----------LVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGS-WDRAPPSCQLVSCGEPPIVKDA-VITGSNFTFGNTVAYTCKEGYTLAGPDTIV--------CQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKI----ECLRGGEWSPSP---LSVQCIPVRCGEPPSIANGYPSGTNY------SFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCN-EPPKVENGFLEHTTGRTFESEARFQCNPGYKAA--------GSPVFVCQANR-HWHSDAPLSCTPLNCGKPPPIQNG--FLKGESFEV-----------GSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPL 2327 HSP 9 Score: 85.8853 bits (211), Expect = 8.427e-16 Identity = 108/472 (22.88%), Postives = 171/472 (36.23%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEY---DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICT-AILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG--ETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+V S VK L + CP + N+ W ++ ++ V S + C ++ P ++P +G+ G +V C G+ + G +YC + + P C + C +P + + +DF G V C +GY S + NG+ P + C D + N N +Y C + ++GD C + C PENG G TV + TF C EG++L G C G WD +C +CG PP V A T+G++ Y+C TL G E++ L G + S P C L K E+ +I+ +T+ + C GY L L C +GSW+ P + PP +K + + + + Y C GY +A
Sbjct: 1581 YVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSV-PHLRPASGNRKP-----GSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHC--ERIRCG----LPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSY----------------------------VCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSS-------PVCEL---------VKCSQPEDINNGKYILSG-LTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLA 1995 HSP 10 Score: 80.1073 bits (196), Expect = 5.220e-14 Identity = 104/448 (23.21%), Postives = 161/448 (35.94%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE-TSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPS-MKYSTVRFLSLKHDSLARYYCHFGYYI--ALRKDGMETLSTIFDIKCNKGNWTKMPT 1715
QC P N L + V Y+C+ GY ++G C S P C + C P + ++ + K VK+ C GY + W + I C K C + R ++ + +++ C +GF E N CQ DG W + C ++C P +G V+G ++ S ++C GY+L G+ R C W G + C C P E K E TT G + C TL G + T N L KP P C + PF + V + E +V KC G+ L + + C + +W RC + +C PPS ++ + R + ++ + Y C+ GY + +LR +E G WT P
Sbjct: 3059 QCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLS--CGPPPTVANAVATGEAHTYESK----VKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVS-CAEGFT-------HEGVN-WSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNP-CPV---PFVIPENAV-----------LSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCG--PPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLE-----------NGTWTPSPV 3463 HSP 11 Score: 72.7886 bits (177), Expect = 9.886e-12 Identity = 91/388 (23.45%), Postives = 145/388 (37.37%), Query Frame = 3
Query: 441 SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEW----KYDPIKCEKKSCGKLEDPKNG--RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD--TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF--IPRCVEAACSARPPSMKYSTV 1568
S G+ V YTCK GY L GP CQAN + + S +C + C P + H + G+ C +GY S +I GN W +C C K ++ + S+ C +GF + + + + +C G+WS + C + C E NG G + ++ + C +G+ + G C G W TC +C PP++ + + T ++A ++C G F+ N+ P L C P ++ K +N F+ + G+ V+ CN GYEL D C +G W+ P+CV C A PP ++ V
Sbjct: 1976 SNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVS--CDEPPNVD----HASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGN-WVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVL--------NTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVC---QANRHWHSDAP-----LSCTP--LNCGKPPPIQN----GFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKC-AEPPLLENQLV 2333 HSP 12 Score: 70.8626 bits (172), Expect = 3.285e-11 Identity = 66/247 (26.72%), Postives = 98/247 (39.68%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-KLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGS 1118
I + C P P +G + G + Y C GY L+G R+R CQ N + SG C + + C + P + + ++ +G + C GY E ++H A NG W + C+ C P+N Y Q+++I+ C +GF ++ N C D W+ A C I C S EN GV+ + T+ C GY L GS C G W S
Sbjct: 3233 IPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRE--NRCETPAEFP----NGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTA--NGT-WNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIK-CREGFLLK--------GNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPS 3461 HSP 13 Score: 60.4622 bits (145), Expect = 5.654e-8 Identity = 55/232 (23.71%), Postives = 88/232 (37.93%), Query Frame = 3
Query: 462 QVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVM--GVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG 1148
Q E C+ GY KG + C A + C P + +T +++ +D +C+ GY+ ++ CE C L+ P+NG + N + + A C GF + ++ CQ +G WSG + C CP L P++G + + N++ C EGY+L GS C WDG C+ R+C
Sbjct: 303 QFECICEKGYYGKG-LQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPED--------CVCREGYQRSGQT-----------------CEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHL--------CQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCA 500 HSP 14 Score: 53.9138 bits (128), Expect = 5.544e-6 Identity = 53/218 (24.31%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKN--GRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI 965
+E +R ++C + G V + + +C+ P + NG A G + ++C GY L+G + +C AN + P C + + C IP V + +F ++V I C+ G+ K + + C+ +E W + +CEK SCG +N R +Y Y Y + C G+ ++ + R C +G W+ + +C A+
Sbjct: 3269 LEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLC--KPNPCPVPFVIPENAVL---SEKEFYVDQNVSIKCREGFL--LKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVY---YQYGDMITYSCYSGYMLE--------GSLRSVCLENGTWT-PSPVCRAV 3467
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Match: sp|Q96PZ7|CSMD1_HUMAN (CUB and sushi domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CSMD1 PE=1 SV=3) HSP 1 Score: 120.168 bits (300), Expect = 1.761e-26 Identity = 114/472 (24.15%), Postives = 180/472 (38.14%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFK------------------------------------IQCTTDQFEDKNCRRQCQA----------------DGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
+ + C P P N + G V Y+C+ +L G R CQ + SG+ P CT + C P T H + DDFK ++ C+ G++ NG+ P+ CE SCG P NG + ++ + S I C +G+K IQ TD +K QC DG+W+ +C A+LCP+ P +NG V G S ++ C +GYQL S + C G W G C+ CG P +++ ++ T+ ++ ++CKS L+G + V G +P C+ D + N + + EV G+ V +C GY + C N +W+ I C+ AC +P + ++ VR + L Y CH G+++A
Sbjct: 2855 LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPV-CEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR-----RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY----EV--GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR-QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3309 HSP 2 Score: 107.457 bits (267), Expect = 1.960e-22 Identity = 134/532 (25.19%), Postives = 204/532 (38.35%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC---KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL---NGHWSPPQMPTCEFIM 1949
+ C P NG+ ++ + G +TC +GY L G R C AN SGSE C C S P V+ + + D F + V C G+ S I ++W C +CG +P +G T + + + CN G+ +Q + R QC+++G+WS C + C + EN G N S + + CK+G+ L GS C G WD S C+ +CG P A + E T+GA Y C+ +LIG + + C E + SG LP HC P H + + D+ + +R C G++L C NGSW+ + P C +C V + S Y C GY + G+ T + G WT + C C P T NG + +D T N+ V Y+C+P Y ++ A +G W+P + P C+ ++
Sbjct: 2620 ISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL--AGHCGS----PDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRIC-LQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGYLLQGVS--------RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRV-CQEDSHWSGALP--------HCTGNNPGFCGDPGTPAHGSR------LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY----KTSGLMTRHCTAN-----GTWTGTAPD-CTIISCGDPGTLANGIQF---GTDFT----------FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK-PVCKAVL 3096 HSP 3 Score: 99.3673 bits (246), Expect = 5.992e-20 Identity = 105/447 (23.49%), Postives = 160/447 (35.79%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR-DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQV------DSAKVYIHENNKTTNFI-MHDEVTHGTHVRAKCNFGY---ELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
++C+ D G + + + C P P +G N S + D V +TC +GY L+G + C++N + S P C + C ++ H N + F+ G + C+ G+ S + NG W KC SCG P N + +TY ++ C + N R CQ D WSG CT C + P +G +G S+ F C+ G+QL GS R C G+W G C +CG P + S L + C E SG + + HC D + + N I + T V +CN GY + S + +G WN +A +PP ++ TV + S Y C GY ++
Sbjct: 2717 VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-LWDRSLPKCLAISCGHPGVPANA-VLTGELFTYGAVV--------HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV--------------SSDGILFSSSVIYACWEGYKTSGLMTR-------HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 3130 HSP 4 Score: 98.5969 bits (244), Expect = 9.132e-20 Identity = 108/424 (25.47%), Postives = 161/424 (37.97%), Query Frame = 3
Query: 423 NGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQAN-LRLSGSEPECTDQTDLCFSAP-YIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-W--KYDPIKCEKKSCGKLEDPKNGRTMYN------NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF------LSLKHDSLARYYCHFGYYI 1631
G N + VG +V Y CK GY + G C+ N L + + T LC + IP + + + ++F V C G++ A C + W K P C+ +C +E + ++ N Y Q + + C+ + + +CQA+G W+ GD C I C LS P NG +G + F C GY L GSH+R+C G W GS + C+ +CG P IV ++ + ++ Y+C L+G TS C + SG P C P H N F E V CN GY L C NG W+ +P C CS P + +R S ++ Y+C G+Y+
Sbjct: 2441 GGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY----QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL----------LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG-TSVRICLQDHKWSGQTPV--------CVPITCG------HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD--PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2833 HSP 5 Score: 62.3882 bits (150), Expect = 1.502e-8 Identity = 46/187 (24.60%), Postives = 76/187 (40.64%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
C P P G + +V + CKS + L G +R CQA+ SG +P C D P P+ + ++S ++ G V C+ GY + C N W +C +C + E P + + T+ + C+ GF + ++ R C+AD KW+G + +C
Sbjct: 3155 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSR--GYEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEH-------RTCKADMKWTGKSPVC 3330 HSP 6 Score: 58.5362 bits (140), Expect = 2.458e-7 Identity = 125/543 (23.02%), Postives = 185/543 (34.07%), Query Frame = 3
Query: 396 QCQPP--VQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY----------------EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREG----NWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+CQPP V +GD V+Y C GY L G C+ + L+ GS P C Q P +V S+ +I GY E Y I +E ++D ++ S G + P + + N+T QS N ++ +TD K + A A C P +NG ++ V S + CK GY++ G C R WD C +CG P T ++ Y+C L E+S W K +P CKP S + + E+ + +G V C+ GY L L C NG+WN P C +C + + + L++ + + A + C+ GY + + E L+ G W+ T C C P NG I G S R V Y+C+P +RL G + +CL H Q P C
Sbjct: 2257 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ---------CPANEVRTGSS----------GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG--QSPL--LVVLSGNHTEQSNFTSRSNQ-LYLRWSTDHATSKKGFKIRYA------------APYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWSNKGKPPT---CKPVACPSIEAQLSEH-VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV-YGATAIFTCNTGYTL-VGSHVRECLA--------NGLWSGSETR-CLAGHCGSPDPIVNGHISGDGFSYR-------------DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2733
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Match: sp|Q4LDE5|SVEP1_HUMAN (Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SVEP1 PE=1 SV=3) HSP 1 Score: 116.316 bits (290), Expect = 3.223e-25 Identity = 146/576 (25.35%), Postives = 217/576 (37.67%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTD-------------LCFSAPYI-----PYTQVHDN-----------------SNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-----NFIPRCVEAACSARPPSMKYSTVRFLS---LKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGN-WTKMPTE-GCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELP 1964
C I PP++ NG + G V Y C +GY L G + +C N +G P C D + L YI PYT N S+ + + G +V CQ GY+ + I +G EW + C+ SCGK P+NG + +T+ S CN G+ + DK C A+ WS +C + C NG+ + T S ++ C GY L G + +CT G WD + C + CG PP I A + T Y CK TL G + + G + + +CL D + H + +T + + D + C+ GY L + C G W +PRC+ C +PPS+ YS + +S S+ + C G+ L+T I+C +G W P C P +C +PP+ NG Y G + +V Y C+ + +KG K + C G WS P +PTC + E P
Sbjct: 1685 CERISCGVPPPLE--NGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESG-EWNHLIPYCKAVSCGKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLA------GDK--ESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLAD-----GKWSRSDQQCLA----VSCDEPPIVDHASPETAHRLFGDIAFY------YCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCE-KPPSVSYSILESVSKAKFAAGSVVSFKCMEGF----------VLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNG--YASGSNYS-----------FGAMVAYSCNKGFYIKGEKKSTCEATGQWSSP-IPTCHPVSCGEPP 2208 HSP 2 Score: 115.161 bits (287), Expect = 8.022e-25 Identity = 125/523 (23.90%), Postives = 204/523 (39.01%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDT-AICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFA-KVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P +NG+A+ S G V Y+C G+ +KG +K C+A + S P C + C P + + + R F++ +V+ C GY+ + + N + P+ C CGK +NG M N+ S FCN+G+++ + CQ GKW+ + C CPE EN V+ T + TF CKEG+ L G + KC W+ S C + C PPP I F + A G+ +Y C L G ++ L G P P+C+ + C +P ++ + + + + + + C G+EL + C NG W P C C +P + + L + Y C+ G+ R +G L+ + G+W + C C P +NG + S + ++ Y C P +++ G + C WS +PTC
Sbjct: 2142 IPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVS--CGEPPKVENGFLEHTTGRI-FES--EVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNG-FMKGENFEVGSKVQFFCNEGYELV--------GDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLC-----QPDGTWSSPLPECVPVECPQPEEIPNGIIDVQ------------GLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC-LKPKEILNGKFSYTDLHYGQTVTYSCNRGF----RLEGPSALTCL-----ETGDW-DVDAPSCNAIHCDSPQPIENGFVEGADYS-------------YGAIIIYSCFPGFQVAGHAMQTCEESGWS-SSIPTC 2608 HSP 3 Score: 109.768 bits (273), Expect = 3.510e-23 Identity = 109/424 (25.71%), Postives = 165/424 (38.92%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE--NGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKD 1646
I ++C P P NG + +G V+Y+CK G+ L G R C N + SG+ P C + C P ++ + ++ + C GY + + N W D C C NG+ + + YT+Q CN+GF ++ R C A+G WSG T C + C +PP+ NG G+ TF C EGY LHG+ C +GNWD C NCGPP ++ + HG +Y+C L G +S C + SG P C P + + + N T + G R +C G++L C +G W+ P C +C + P + + + S +++ Y C GY I D
Sbjct: 2713 ISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRC--EAISCKK----PNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKN-WDEDEPICIPVDCSSPPVSANGQ-VRGDEYTFQKEIEYTCNEGFLLEGARS--------RVCLANGSWSGATPDCVPVRC--ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSS-RRCLSNGSWSGSSPS--------CLPCRCSTPVIEYGTVNGT-------DFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSL-PMIPNAFISETSSWKENVITYSCRSGYVIQGSSD 3101 HSP 4 Score: 101.293 bits (251), Expect = 1.412e-20 Identity = 135/580 (23.28%), Postives = 221/580 (38.10%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTY-QSIAIQF-CNDGFKI------------------------QCTTDQFE-------DKNCRRQ------------------CQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACS----ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCE 1940
+C+ +D C P NG ++EYTC G+ L+G R R C AN SG+ P+C C + P + + + D+ ++V C GY + + +GN W + C+ +CG ED +G + N +++ IQ+ C G+K+ +C+T E D +C + C+ADG+WS C C L N + + ++ T+ C+ GY + GS CT +G W C +CG PP + A EA T+ ++ + +C T+ +T TC + D + W P+ + C P K + EN T+ ++H D+ + V C GY + C +G+W P + +CS +P S ++ V +S Y C GY + +GN ++ E Q E L + + + +++ P V Y C+ Y L+GP A C NG WS P +P C+
Sbjct: 2827 ICIPVD--CSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVR--CATPPQL----ANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGN-WDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTC-QKDGR--WFPE-----RISCSP-----KKCPLPEN--ITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYEL-------------------EGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGP----NVVYSCNRGYSLEGPSEAHCTENGTWSHP-VPLCK 3353 HSP 5 Score: 93.5893 bits (231), Expect = 4.133e-18 Identity = 145/613 (23.65%), Postives = 223/613 (36.38%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSIL--LVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSE----PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTV-NSIKTFKCKEGYQLHGSHLRKCTREGNWDG-SNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG-WLPKPEPKCL-----------------------------------------LHCKPFQ-----VDSAKVYIHENNKTTNF---IMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTK-MPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDE-LPISWLYYRSDDKK*EDYVFYLHF 2030
+ + C P P+ HA+ L GD Y C GY+L + C A + E P C C P + Y+ + ++ ++ F G V C G+ + I G +W P I+C CG+ NG +NY++ ++ CN GF I+ + C+A G+WS C + C E ENG + + S ++C GY+ GS + C +W S C+ +CG PP I + E G++ ++ C L+G++S+ TC KSG W K PKC+ L C P Q K+ + +F I + G+ V+ C G+ L + C +G+W+ +P CV C +P + + L + S A Y C K G E + + G+W PT C+ +C KP NG+ TD + + V Y C+ +RL+GP CL G W P+C I D PI + D + Y F
Sbjct: 2017 LAVSCDEP--PIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAH--FCEKPPSVSYS-ILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM-RGGQWNPSPMSIQCIPVRCGEPPSIMNGYAS-GSNYSFGAMVAYSCNKGFYIKGEK--------KSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSW-TC----QKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVEC-PQPEEIPNGIIDVQGLAYLSTALYTC---------KPGFELVGNTTTLCGENGHWLGGKPT--CKAIECLKPKEILNGKF---------SYTDLH----YGQTVTYSCNRGFRLEGPSALTCLETGDWD-VDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCF 2583 HSP 6 Score: 92.8189 bits (229), Expect = 7.034e-18 Identity = 136/541 (25.14%), Postives = 207/541 (38.26%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGK--LEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKW----SGDTAICTAILC---PELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYE-LNSDILPACYNGSWNFIP--RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPI 1967
++C P NG S L Y+C +GY+L+GP C A+ + P C C P I + N +F V C+ GY I +G +W +C SC + + D + T + + IA +C+DG+ + N + C A GKW D C A C P +S V S+ +FKC EG+ L+ S +C R G W+ S + CI CG PP I+ + + GA Y C + GE TC S +P P + C +P +V++ + TT I EV R +CN GY+ + S + N W+ CV C +PP ++ ++ + + S +++C+ GY L D T C K G W K C P KC +PP +N +L K + VV + C + L+GP + CL P C+ ++ P+
Sbjct: 1903 VKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC--HLVFCGEPPAIKDAVITGN----NFTFRNTVTYTCKEGYTLAGLDTIECLADG-KWSRSDQQCLAVSCDEPPIVDHASPETAHR---LFGDIAFYYCSDGYSLA--------DNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKK-STCEATGQWSSPIPTCHP---VSCGEPPKVENGFL-----EHTTGRIFESEV------RYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDC-GKPPPIQNGFMKGENFEVGSKVQFFCNEGY--ELVGDSSWT--------CQKSGKWNKKSNPKCMPAKCPEPPLLEN------------QLVLKELT-TEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPL 2386 HSP 7 Score: 87.8113 bits (216), Expect = 2.296e-16 Identity = 140/610 (22.95%), Postives = 202/610 (33.11%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-------------------------DQTDLCFSAPYI----PY-----------TQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEP-KC------------------------------LLH-------------------CKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCE 1940
+ C P NG + G + Y+C G+ + G + C+ + S S P C +Q D PY+ PY T+ ++ +F G V C GYE +I + +G W C C P+NG + T A+Q+ C + R C + KWSG + C AI C + +P NG + G T S ++C GY L+G+ R C + NWD CI +C PP +V + T + EY C L G S + C + SG P P +C +LH CKP + H +FI HG H++ +C GY+L+ + C NGSW+ P C+ CS P ++Y TV AR C G+ L + +I C G W+ C+ C P N I V+ Y C Y ++G +C G WS P P CE
Sbjct: 2554 IHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEES-GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGT-WNGSAPSCISIECDLPTAPENGFLRFTE--TSMGSAVQY-------SCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRV-CLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFI------HGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST--PVIEYGTVNGTDFDCGKAARIQCFKGF----------KLLGLSEITCEADGQWSSGFPH-CEHTSCGSLPMIPNAFI-------------SETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQP-YPVCE 3118 HSP 8 Score: 84.3445 bits (207), Expect = 2.719e-15 Identity = 133/585 (22.74%), Postives = 201/585 (34.36%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANH-----SILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQ-SIAIQFCNDGFKIQCTTDQFEDKNCRR--QCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG--ETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNS-DILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNR----VVKYECHPLYRLKGPKIAVC-LNGHWSPPQ---MPTC 1937
+V S VK L CP + N+ W ++ S + G V ++ + G H L G +V C G+ L G +YC + + P C + +P + + DDF G V C NGY S + NG+ P + C D + N + +Y S + DG KNC +C+A G PENG G TV + TF C+EGYQL G C G W+ C +CG P + A T G++ Y+C TL G E+S L S W P C+P + S EN +I+ +T+ + C+ GY L I+ +G W+ P PP++K + + + + Y C GY +A G++T+ + D G W++ + + L D + D + +R + Y C Y L +C G W PP+ MP C
Sbjct: 1582 YVLSPQQVKSLATSCPEELSKGNVLAWPDFL--------SGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISC------GVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDG------------KNCAEPIKCKAPGN------------------PENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLA------NSSWSHSPP-----VCEPVKCSSP-----ENINNGKYILSG-LTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLA----GLDTIECLAD-----GKWSR------------------SDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2078 HSP 9 Score: 79.7221 bits (195), Expect = 6.353e-14 Identity = 96/421 (22.80%), Postives = 152/421 (36.10%), Query Frame = 3
Query: 465 VEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA--LRKDGMETLSTIFDIKCNKGNWTKMP 1712
+ Y+C+SGY ++G C S P C + C S P + ++ + +VK+ C GY + W + I C K C L + ++ ++++ C +G+ FE N CQ DG W + C+ + C + PE+G V+G T S ++C+ GY+L G+ R C W G + C C P E + K E T G Y C +L G + C E +G P P C + P I EN + E +V KC G+ L + C + +W E P ++ + R + ++ + Y C+ GY + LR +E G WT P
Sbjct: 3086 ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS--CGSPPSVANAVATGEAHTYE----SEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKC-PLPENITHILVHGDDFSVNRQVSVSCAEGYT-------FEGVNISV-CQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSE-AHCTE----NGTWSHPVPLCKPNPCP-----VPFVIPEN----ALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLE-----------NGTWTSPP 3466 HSP 10 Score: 68.5514 bits (166), Expect = 1.803e-10 Identity = 62/242 (25.62%), Postives = 95/242 (39.26%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-KLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNW 1109
+ C P P +G S + Y C+ GY L+G R+R CQ N + SG C + + P ++ ++ ++ G +V C GY E P ++H NG W + C+ C P+N Y Q+++I+ C +GF +Q + C D W+ +A C I C + EN GV + T+ C GY L G C G W
Sbjct: 3239 VSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKE------TRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTE--NGT-WSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIK-CREGFLLQ--------GHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTW 3462 HSP 11 Score: 65.0846 bits (157), Expect = 2.218e-9 Identity = 57/216 (26.39%), Postives = 95/216 (43.98%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI 965
+E +R ++C + G V + + +C+ P++ +NG A+ G V Y+C GY+L+GP + +C N S P C + + C IP + + +F ++V I C+ G+ + H I CN +E W KCEK SCG +N +Y Y + C G+ ++ R C +G W+ IC A+
Sbjct: 3273 LEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLC--KPNPCPVPFVIPENALL---SEKEFYVDQNVSIKCREGFL--LQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENA-IARGVHYQYGDMITYSCYSGYMLE--------GFLRSVCLENGTWT-SPPICRAV 3471 HSP 12 Score: 55.4546 bits (132), Expect = 2.019e-6 Identity = 46/181 (25.41%), Postives = 72/181 (39.78%), Query Frame = 3
Query: 753 CEKKSCGKLEDPKNGRTMYN--NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKT--FKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGP---PPEIVFA--KVAYEATTHGAQAEYKCKSRSTLIGETSFLTC 1268
CE C L+ P+NG + N NN+ + ++ C+ GF + ++ C +G WSG + C CP L P++G + + T C EGY+L GS C WDG C+ R+C P +++ + + G C+ L G L C
Sbjct: 373 CELVHCPALKPPENGYFIQNTCNNHFNAACGVR-CHPGFDLVGSSIIL--------CLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRC 544
BLAST of C4b binding protein beta chain vs. TrEMBL
Match: A0A0X3NX16 (Protein lev-9 OS=Schistocephalus solidus OX=70667 GN=LEV9 PE=4 SV=1) HSP 1 Score: 453.751 bits (1166), Expect = 6.891e-147 Identity = 239/638 (37.46%), Postives = 350/638 (54.86%), Query Frame = 3
Query: 282 CPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYI------PYTQVHDNSN--RDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTD-----QFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCK-------------PFQV--------DSAKVYIHENNKTTNFIMH--DEVTHGTHVRAKCNFGYELNSD---ILP--------ACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGM----------------------ETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYEC-HPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
CP K C AN+DCWV Y + Q CVCD CGLVC+ + +C PP P NG + VGD EYTC G+ + GPRKR+C L+ SG EP CT+QTD CFS PYI +T+ ++S+ R+D++ G+ + + C++G+EDP + + C GN+WKY+ + C++ SC +++ P NGRT+Y ++ Y++ A+QFCNDG I+C +D Q ++++C R CQADG+WSG A CT I CP+L P++G + G W VNS+ F+C+ GY+L GS R+C +G WDG C +R+CGPPP I FA V Y +T G++A +KC+S + +S L C +NK+ WLP P P C +C P V D+ ++ +++ + ++H + HGT +R C G+ L D I+P C +GSWN +C+ A C RPP++ + VRF S+ H S+ RY C G+ + K T ++ ++C G W E C P C +P + +I+L+G R SI P H VV Y C YR+ GP+ A C+ G W+PP +PTCE I HD +P +WL++R
Sbjct: 74 CPQKTCRANVDCWVAYGKPQQCVCDPQFCGLVCLPVGARCPPPYLPSNGFVSFRDSKVGDMAEYTCAPGFTVMGPRKRHCLGTLQWSGPEPICTNQTDYCFSPPYIQNAIVLEHTKFGEDSSQERNDYRTGDSITMTCRSGFEDPARKYTTVLCVGNQWKYEKLDCQRISCPEIDGPVNGRTIYTSDLRYRATAVQFCNDGHAIKCPSDAEGVVQRDEESCMRVCQADGRWSGGNAECTPIQCPQLEKPDHGSLSGFWTKVNSVVAFECEIGYELIGSPFRRCQLDGKWDGDPVICKIRDCGPPPNIRFAAVKYSSTIFGSRAYFKCESGTVPSVSSSELVCKTHNNKTMWLPFPYPACYRYCSLPVVAQSSISIVAPGGVKVEGESPLDNGEILPASTSQSADEVVHLDSQTEHGTVIRIACKSGFNLVLDQQKIIPTSETEGQAVCNDGSWNSSYKCIPARCKQRPPTVANAIVRFYSMSHGSVVRYQCLPGFILEASKMHTGSEDLLSSSESEEEKVNRDLVWGTQHDLYSVRCEFGEWRGRRPE-CVPIHCKRPIVVEGVQIHLIGARGRWPFESDSIYPTHGAVVVYSCAQEGYRINGPRYAFCIEGAWNPPTIPTCELITHDIIPSNWLFHR 710
BLAST of C4b binding protein beta chain vs. TrEMBL
Match: A0A068WN99 (C4b binding protein beta chain OS=Echinococcus granulosus OX=6210 GN=EgrG_000439500 PE=4 SV=1) HSP 1 Score: 441.81 bits (1135), Expect = 1.186e-142 Identity = 235/609 (38.59%), Postives = 339/609 (55.67%), Query Frame = 3
Query: 282 CPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHD--------NSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQC-----TTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKV-YIHENNKTTNFIMHDE--VTHGTHVRAKCNFGYELNSDIL---------PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI-------ALRK----DGMETLSTI----FDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYEC-HPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
CP + C AN+DCWV Y + Q CVCD + CGLVC+ + +C PP +P NG+ VG V+YTC +G+ + GPRKR+C A SG EP CT+QTD CFS PYI V + + +R D+++GE + + C+ G+ D + + C GN+WKY + C + SC +++ P+NGRT+Y ++ YQ A+QFCNDG+ I C T+ K+C R CQADG WSG +A C A+ CP+L PENG + G VNS+ F+C EG++L GS RKC G W+G + C VR+CG PPEI A V + +T++G++A + C++ + TS L CG + NK+ WLP P P C HC + SA + ++ N K I+ +E + HG + C+ G+ L+ + C NG W+ C A C+ RPP++ + RF L H S+ RY C GY + ALR+ G+ + + ++C G W K C +C +PP P+ EIYL+G R K I P H VV+Y C +R++GPK C++G WSP + P C I HD +P+SWL+Y+
Sbjct: 74 CPKRTCRANVDCWVAYGKPQQCVCDPHFCGLVCLPVGSRCSPPNKPENGNILLRDTRVGATVDYTCDAGFTVMGPRKRHCLATRSWSGPEPVCTNQTDHCFSPPYIQNAMVIEGHWLEAKISRDRADYRSGESITMTCRPGFVDAKRKYSTIVCVGNQWKYKKLDCHRVSCPEIDGPENGRTLYTSDMRYQGTAVQFCNDGYTIHCPGETVKTEPTSSKSCSRVCQADGTWSGKSAKCIAVTCPKLQQPENGFISGYQTKVNSVVAFECAEGFKLKGSSFRKCQLNGEWNGEPAQCQVRDCGSPPEISNAVVKFSSTSYGSKAYFSCEAGTKSSVSTSELICGRIGNKTSWLPFPYPACYKHCSVPDIVSANISLLNMNGKPDGDIVAEETLLEHGVTIAVYCHSGFSLSKGKIRLDQGAFTTTTCENGKWSHKVECQPAQCTTRPPNIPNALARFYGLHHGSVVRYQCFPGYELDTNRTEAALREAASTGGLANTWPLAHDRYSVRCEYGVW-KGELPACVQVRCNRPPVPEGMEIYLVGARGRWPFDSKQILPTHGAVVEYSCLKDGHRIEGPKYTFCIDGSWSPDETPICTKITHDIIPLSWLFYK 681
BLAST of C4b binding protein beta chain vs. TrEMBL
Match: A0A0R3S8B5 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS374 PE=4 SV=1) HSP 1 Score: 438.343 bits (1126), Expect = 1.047e-141 Identity = 226/609 (37.11%), Postives = 336/609 (55.17%), Query Frame = 3
Query: 282 CPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHD--------NSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQ-----FEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTN---FIMHDEVTHGTHVRAKCNFGYEL---------NSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI-----------ALRKDGMETLSTI----FDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYEC-HPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
CP + C AN+DCWV Y + Q CVCD + CGLVC+ + QC P +P NG+ +G +Y C +G+ + GPR+R+C A L+ SG EP CT+QTD CFS PY+P V + +S+R D++NGE + + C+ G+ D + + C GN+WKY+ + C++ SC +++ PKNGRT+Y ++ +Q+ AIQFC+DG+ I+C+ + K+CRR CQ DG WSG +A C A+ CP+L PENG + G VNS+ F+C EGY+L GS RKC G W+G + CIVR+CG PPEI A + + +TT ++A + C + + ++S L C +V NK+ WLP P P C HC+ + +A + + + T N + + H T + C GY L S C NG+W+ C A C+ RPP++ + RF L H S+ RY C G+ + +R G+ + + +KC G W P C C +PP P E+YL+G R + P H V++Y C +R++GP+ + C++GHWSP + P C I HD +P SWL+Y+
Sbjct: 49 CPKRTCRANVDCWVAYGKPQQCVCDPHFCGLVCLPVGSQCPMPNKPENGNVLLRDSGIGGAADYICDAGFTVMGPRQRHCLATLKWSGPEPVCTNQTDYCFSPPYMPNAVVIEGHWLEDKTSSDRADYRNGEIITMTCRPGFADAKRKYSTVVCLGNQWKYEKLDCQRISCPEIKGPKNGRTLYTSDMRFQATAIQFCDDGYNIRCSEETENKEPSSAKSCRRVCQEDGTWSGKSAECIAVTCPKLQQPENGFISGYQTNVNSVVAFECAEGYELTGSKFRKCQANGEWNGEQAKCIVRDCGKPPEIKNAAIKFSSTTFNSKAYFSCDAETKSSIKSSELICSQVGNKTTWLPYPYPSCYKHCRVPDITNASITLTNLSGTPNKEVVKVGTLLEHDTSISISCQSGYNLAEGLTKPLQRSSATTLCKNGNWDHKYECQPARCTTRPPNIPNALARFYGLHHGSVVRYQCFPGFELDTNRTEVLLRKVVRNGGLTNTWPLTHDRYSVKCEYGVWKGEPPT-CVHVHCNQPPVPVGTEVYLVGSRGRWPFDARQGLPTHGAVIEYACLKDDHRIEGPRFSFCIDGHWSPDETPNCTKITHDVIPPSWLFYK 656
BLAST of C4b binding protein beta chain vs. TrEMBL
Match: A0A068Y4F2 (C4b binding protein beta chain OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000439500 PE=4 SV=1) HSP 1 Score: 434.106 bits (1115), Expect = 1.080e-139 Identity = 231/609 (37.93%), Postives = 335/609 (55.01%), Query Frame = 3
Query: 282 CPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHD--------NSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQC-----TTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVT---HGTHVRAKCNFGYELNSDIL---------PACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI-------ALRK----DGMETLSTI----FDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYEC-HPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYR 1985
CP + C AN+DCWV Y + Q CVCD + CGLVC+ + +C PP +P NG+ VG V+YTC +G+ + GPRKR+C A SG EP CT+QTD CFS PYI V + + +R D+++GE + + C+ G+ D +++ C GN+WKY + C + SC +++ P+NGRT+Y ++ YQ A+QFCNDG+ I C T+ K+C R CQADG WSG +A C A+ CP+L PENG + G VN + F+C EG++L GS RKC G W+G + C VR+CG PPEI A V + +T++G++A + C++ + T L CG + NK+ WLP P P C HC + SA + + N + + E T HG + C+ G+ L+ + C NG W+ C A C+ RPP++ + RF L H S+ RY C GY + ALR+ G+ + + ++C G W K C +C++PP P+ EIYL+G R K I P H +V+Y C +R++GPK C++G WSP + P C I HD +P SWL+Y+
Sbjct: 74 CPKRTCRANVDCWVAYGKPQQCVCDPHFCGLVCLPVGSRCSPPNKPKNGYILLRDTRVGATVDYTCDAGFTVMGPRKRHCLATRSWSGPEPVCTNQTDHCFSPPYIQNAMVIEGHWLEAKISRDRADYRSGESITMTCRPGFVDAKRNYSTIVCVGNQWKYKKLDCHRVSCPEIDGPENGRTLYTSDMRYQGTAVQFCNDGYTIHCPGETVKTEPTSSKSCSRVCQADGTWSGKSAKCIAVTCPKLQQPENGFISGYQTKVNGVVAFECAEGFELKGSSFRKCQLNGEWNGEPAQCQVRDCGSPPEISNAVVKFSSTSYGSKAYFSCEAGTKSSVSTLELICGRIGNKTSWLPFPYPACYKHCSVPDIVSANISLLNMNGKPDGNIVAEATLLEHGVTIAVCCHSGFSLSKGKIRLDQGAFTTTTCENGKWSHEVECQPAQCTTRPPNIPNALARFYGLHHGSVVRYQCFPGYELDTNRTEAALREAASTGGLANTWPLAHDRYSVRCEYGVW-KGELPACVQVRCSRPPVPEGVEIYLVGARGRWPFDSKQILPTHGAIVEYSCLKDDHRIEGPKYTFCIDGSWSPDETPICTKITHDIIPPSWLFYK 681
BLAST of C4b binding protein beta chain vs. TrEMBL
Match: A0A4S2LP64 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007135 PE=4 SV=1) HSP 1 Score: 400.593 bits (1028), Expect = 8.057e-127 Identity = 224/656 (34.15%), Postives = 330/656 (50.30%), Query Frame = 3
Query: 186 LFLNLINPMKSAQYKPECHVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHD------------NSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQC---TTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHE--NNKTTNFI-------------------------MHDEVTHGTHVRAKCNFGYELNSDILP--ACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL--RKDGMETLSTIFD-------IKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSI----KPIHNRVVKYECHPLYRLKGPKIAVCLNGHWS-PPQMPTCEFIMHDELPISWLY 1979
L+++ SAQY P +S CP+K+C +IDCWV + Q CVCD +LCG VC+ + +C+PP+ P+NG + +GD EYTC+ G+ ++GPR R+C A L SG +P C++QT+ CFS PY+P T+ + +RDD+K+GE ++I+CQ GY+D + ++ A C G+EW+ + CE+ +CG + DP +G ++ ++ Y++ A+ C +GF C + Q C R CQADG WSG IC I CP L PENG + VNSI C GY+L G ++C G WDG + C R+CGP P +V +V E TT G++A + C +T +T L CG +DNK+ WLP+P P C HC F VD V + N + FI V HG + C+ GY+L + P C +G W+ +CV A+C RPP + VRF SLKH++ RY C G+ + + K ++ L+ + I+C G W +P C+P C+K K E+ L + R L + P V + C P + + G +VC NG W+ PP CE HD++P W +
Sbjct: 18 LWMSAFVYPDSAQYTPGNVCESSAQTHPDFMKCPTKSCRQHIDCWVSFGPPQFCVCDRHLCGAVCLPENSRCKPPIAPLNGTVRFNGTEIGDSAEYTCEVGFVVRGPRNRHCLATLSWSGEDPSCSNQTNTCFSPPYMPNTRTRSRPRPEQVSMFSLDIDRDDYKSGEVIEIVCQPGYKDLERDYVEAACVGSEWRVTKLNCERVNCGPIRDPPHGHLVFKSDKRYKAEALAVCAEGFIADCGPSSGTQDSTIGCLRVCQADGTWSGHDTICRPITCPRLDAPENGGISTYSTEVNSIVKVHCNHGYELIGPEQKQCLATGKWDGERTICKERDCGPVPTVVNGRVTAEKTTFGSRAAFTCDPDTTASSDTDSLHCGLIDNKTSWLPQPIPTCNRHCYLFTVDHGDVLLMHKPNTPSQRFIPITSENYPQLESIGNALTSSDGIILPGSRVRHGAQLNVTCHRGYQLVNTAQPITMCMDGVWSVRSKCVPASCRTRPPPAPGARVRFYSLKHEAKGRYECFVGHTLRVDETKQIVQPLNAVGSNDDPLGVIRCLHGEWVGIPVF-CEPVICSKLILHKMVEVELKHPTSRNILMGGTATLEETPRQGTVAHFRCSPGFHVVGTTFSVCHNGTWTPPPNTAHCEKSTHDQIPTEWFF 672
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Match: svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:103042618]) HSP 1 Score: 140.584 bits (353), Expect = 7.503e-34 Identity = 139/525 (26.48%), Postives = 215/525 (40.95%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYN-NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIP---RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
++C+ P P GH ++ +VG +V ++C+ GY L G + C G P C L + P +P + +N F V C+ GY + + +C N +W +P C+ +CG E P + NN Y S C +G+++Q + + QC++ G+W+ +CT + C E SP ++ + G T+ S + C+EG+ L G+ ++C G W +++ C+ R CG PP + A G A Y C T IG S L C N G P+ + HC H + I + T V KC G+ LN+ C G W+ P C+ CS +P S++ V + ++ Y C GYYI R + T G W + CQP C+ PP NG I D R T+ +++ V Y C+ YRL G +C+ N WS P C +
Sbjct: 1789 VKCKDPGHPDFGHREGTVFIVGSEVVFSCEEGYELIGSSRLSCSETGTWEGLFPFCKA---LSCNPPTVPEHGILKGTN---FTYRSKVTFSCEKGYI--LEGTMEIQCESNLKWSSEPPICQPVTCG--EPPAVDHAEFTLNNTVYLSTLAYTCVEGYRLQGSGE--------LQCESTGEWTSPVPVCTRVECGEPSPLKDAVIKGDNFTLGSQVQYICREGFTLLGTETQECLPSGEWSRNSAQCVPRQCGSPPHVDHALSDAGHQLFGDTAIYFCDDGYT-IGNNSKLFC----NAEGVWAPPDGYGMPHCIANFCQRPPELPH---AILDSINKPKYASNTEVSYKCEEGFVLNTTATLKCLLGGDWSPSPLDIGCMPVRCS-KPESIERGYVSGNNYSFGAVVAYSCDKGYYI--RGEKRRTCKA-------NGEWGGV-LPACQPIACSSPPRLINGFI-----QDTIRRTNY----VYSSKVTYACNAGYRLTGKAERICMANKQWSNSDPPACVLL 2267 HSP 2 Score: 125.561 bits (314), Expect = 4.467e-29 Identity = 129/527 (24.48%), Postives = 207/527 (39.28%), Query Frame = 3
Query: 372 LVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS-GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL--NSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
+ CM + +C P G+ + + G V Y+C GY ++G ++R C+AN G P C Q C S P + + D R ++ V C GY K+ I N DP C +C D K+G + + S C++G+++ + + C GKW +C+ + C E +N V+ ++ + C++GY LHG+ +CT W+ S C +CGPPP++ F + + G+ Y C + TL E S ++C G KP P+C+ + C H + + + + C GY+L NS +L +G W +P C C P + + ++ L+ Y C GY R +G ETL+ + GNW K CQ C+ P NG ++ G+ + +T + Y C P + L G C WS +PTC
Sbjct: 2141 IGCMPV--RCSKPESIERGYVSGNNYSFGAVVAYSCDKGYYIRGEKRRTCKANGEWGGVLPAC--QPIACSSPPRLINGFIQDTIRRTNYVYSSKVTYACNAGYRLTGKAERICMANKQWSNSDPPACVLLTCPTPPDIKHGLYSGSTTFEVGSKVEYMCDEGYEL--------NGDAVWTCLKYGKWDKSKIPLCSPVQCQEPPLEDNHLVLRSLDSDSGTVELSCEDGYVLHGARTLRCTPSQEWNDSFPVCKQVSCGPPPDVSFGDPSSASFYFGSVITYSCMAGFTLRKEAS-VSC----QADGSWSKPYPECIPVECP-----------HPEEIPNGIVDVQGLMYLSTALYSCKPGYDLVGNSTVLCG-QSGLWIGGVPACHPIECPP-PKDIPNGSAKYSRLQFSRSVTYSCQRGY----RLEGPETLTCL-----ESGNWDKE-VPSCQQIYCSPPKPIDNG--FVEGRDHKFGVT-----------IFYSCFPGFLLMGQNHLTCEEHGWS-SSVPTC 2613 HSP 3 Score: 105.916 bits (263), Expect = 5.991e-23 Identity = 126/518 (24.32%), Postives = 193/518 (37.26%), Query Frame = 3
Query: 231 PECHVKSLDNVKHLPNGCPSKA-----CTANIDCWVEYDRAQLCVCDSYLCGLVCMEID-------LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD--DFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-----------KLEDPK-----------NGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYY------IALRKDGM 1652
PEC + + +PNG TA C YD L + LCG + I ++C PP NG A +S L V Y+C+ GY L+GP C + P C + +P P DN + D K G + C G+ ++H+ C + W C CG K+ DP R+ + ++ + ++ C+ G+ + + CQ DG W+G +C C PE+G + + S+ + C+EGY+L G +R+C W+ CI NCG P I +V + Y+C + L G S TC ++D K W K P C V S V ++ D T G + CN G+ L+ C N +W+ P+C+ A C RPP ++ R + ++ Y C GY + R DG+
Sbjct: 2438 PECIPVECPHPEEIPNGIVDVQGLMYLSTALYSCKPGYD---LVGNSTVLCGQSGLWIGGVPACHPIECPPPKDIPNGSAKYSRLQFSRSVTYSCQRGYRLEGPETLTCLESGNWDKEVPSCQQ----IYCSPPKPI----DNGFVEGRDHKFGVTIFYSCFPGFLLMGQNHLT--CEEHGWSSSVPTCSPADCGLPPHIDFGDYFKIRDPSAELSGGDNKLAGQRSPTDTSFLHGTMVQYRCHSGYDM--------NGGVVLGCQEDGIWNGTAPVCVPAECEAPPNPEHGLAILTDTVLGSLVEYSCEEGYELEGQTVRQCVSGRQWNDEAPRCIPINCGDPGGISNGEVVGRSFYFKEVIHYECHAGFILQGSES-RTC-QMDGK--WDGK-APSCRAVSCGHPVISNDVQVN----------GDSYTFGKRLVFSCNPGFILHGAATSVCLANSTWSESTPKCLPADC-GRPPIIRNGHARGTNYGYNGKVTYECDVGYTLIGNPSLVCRGDGL 2918 HSP 4 Score: 95.1301 bits (235), Expect = 1.292e-19 Identity = 138/614 (22.48%), Postives = 215/614 (35.02%), Query Frame = 3
Query: 231 PECHVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLC----------GLVCMEI-----------DLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYI----------PYTQVHDNSNR---------DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIP-RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPT-EGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
P CH K +PNG +Y R Q +Y C L C+E + C PP NG G + Y+C G+ L G C+ + S S P C+ C P+I P ++ N+ F +G V+ C +GY+ ++ C + W C C +P++G + + S+ C +G++++ T RQC + +W+ + C I C + NGEV+G + ++C G+ L GS R C +G WDG +C +CG P +V ++ T G + + C L G + + S W + PKCL P + + + + TN+ + +VT+ +C+ GY L + C +G W+ P RC C P + + + S D L Y C GY IA G L D G W ++P C G + G S + + C Y+ GP AVC G P +P C
Sbjct: 2496 PACHPIECPPPKDIPNGS------------AKYSRLQFSRSVTYSCQRGYRLEGPETLTCLESGNWDKEVPSCQQIYCSPPKPIDNGFVEGRDHKFGVTIFYSCFPGFLLMGQNHLTCEEH-GWSSSVPTCSPAD--CGLPPHIDFGDYFKIRDPSAELSGGDNKLAGQRSPTDTSFLHGTMVQYRCHSGYD--MNGGVVLGCQEDGIWNGTAPVCVPAECEAPPNPEHGLAILTDT-VLGSLVEYSCEEGYELEGQT--------VRQCVSGRQWNDEAPRCIPINCGDPGGISNGEVVGRSFYFKEVIHYECHAGFILQGSESRTCQMDGKWDGKAPSCRAVSCGHPVISNDVQVNGDSYTFGKRLVFSCNPGFILHGAATSVCLA----NSTW-SESTPKCL----PADCGRPPIIRNGHARGTNYGYNGKVTY------ECDVGYTLIGNPSLVCRGDGLWDDPPPRCDIVTCDP-PEDISHGFLNGSSFNFDDLVEYICFPGYEIA----GSPILRCTAD-----GTWIGEVPQCRPCMCNPPVLKFGAVLGRDHTCGAS-----------------IWFRCDEGYKTLGPTEAVCDKGGVWSPGVPIC 3041 HSP 5 Score: 92.4337 bits (228), Expect = 8.749e-19 Identity = 97/409 (23.72%), Postives = 150/409 (36.67%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQP---VNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGD--TAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFL 1577
+C PP P V G A G+ V Y C+ GY+L+G C R C + C P +P + ++ F G + C G+E ++ + + W ++C K C P N N + I C + + +C G+WS + C + C + P +G + G + T+ C G++L G ++ C + W G+ C+V +CGPPP + A ++ ++ Y C S LIG + LTC N S LP P + C +P + KV H + G + C+ GY L D C NGSW+ P C +C P STV +
Sbjct: 3040 ICSRGRCSTPPPAVPNAVVTGGAT-----TGETVTYGCRPGYSLRGHPNLSCGRLGRWGVPSLHCDPVS--CGEPPPVPNAMIVGSA----FTYGSKAQYKCSEGFEPVTQTDSVHCQSDGTWSKHSVRCRPKPCSL---PSN-----LTNVVVAGDQLTPVGGTITISCKPGFYLEGPGLSECGLFGRWSPSFSSNSCVLVFCDKPHPLLHGIIKGESYSYGDTVTYTCLPGFELQGDAVQICQGDKKWSGAQPLCVVVSCGPPPSVENAVSLMTGESYESKVTYVCDSGLELIGPQN-LTCQA--NGSWSLPTPTCEAPEDCPRPESILHGKVQ-----------EHSQANGGKALEIFCDKGYALQGDSHIVCMENGSWSSPFPICSPKSCPPLPGWPANSTVFLV 3415 HSP 6 Score: 88.9669 bits (219), Expect = 1.040e-17 Identity = 111/501 (22.16%), Postives = 182/501 (36.33%), Query Frame = 3
Query: 240 HVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKC-------------EKKSCGKLE-------------------DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKS-GWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMH-DEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+V S ++ L + CPS N+ W ++ R S + C + L + V N ++ + G QV+++C GY L G ++CQ S + P+C C + P + + Q H +DF G V+ C+ G+ +S + N +W +P C E SC + +P + + ++ ++ + C + R C G W G C A+ C + PE+G + G T S TF C++GY L G+ +C W C CG PP + A+ T + + Y C L G GE+ +S G P P C +V E + + ++ D T G+ V+ C G+ L C +G W+ +CV C + PP + ++ A Y+C GY I
Sbjct: 1584 YVLSPQQIRSLASSCPSDLQRGNVFAWPDFLRGVTGRVKSSSNSMFCADCPLL-ENAVS--NLRSSSPAVSPGSQVKFSCNPGYYLVGEPVQHCQNRGAWSHAAPQCERVN--CGAPPPLEHGQYHG----EDFYAGSSVEYQCRPGFYLLGESKMHCA-NSGKWAGNPPACLDVDECALGSDCDEHASCQNTDGSHICTCIYPYTGDGRNCTEPVKCKDPGHPDFGHREGTVFIVGSEVVFSCEEGYELIGSSRLSCSETGTWEGLFPFCKALSCNPPTVPEHGILKGTNFTYRSKVTFSCEKGYILEGTMEIQCESNLKWSSEPPICQPVTCGEPPAVDHAEFTLNNTVYLSTLAYTCVEGYRLQGS------GELQCESTGEWTSPVPVC-----------TRVECGEPSPLKDAVIKGDNFTLGSQVQYICREGFTLLGTETQECLPSGEWSRNSAQCVPRQCGS-PPHVDHALSDAGHQLFGDTAIYFCDDGYTIG 2056 HSP 7 Score: 88.1965 bits (217), Expect = 2.099e-17 Identity = 128/520 (24.62%), Postives = 192/520 (36.92%), Query Frame = 3
Query: 402 QPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTH-GTHVRAKCNFGYELNSDILPAC-YNGSWN---FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
+PP+ NGHA + +V Y C GY L G C+ + P C D+ P P H N F + V+ IC GYE I +C + W + +C C K G + ++ SI + C++G+K T+ DK G WS IC+ C P V+ T T+ C+ GY L G C R G W + C +CG PP + A + A T+G++A+YKC + +T + C + W K + C+P K +N T + D++T G + C G+ L L C G W+ CV C +P + + ++ S + Y C G+ L+ D ++ C C C PP+ +N + G+S +++T Y C L GP+ C NG WS P PTCE
Sbjct: 2875 RPPII-RNGHARGTNYGYNGKVTYECDVGYTLIGNPSLVCRGDGLWDDPPPRC----DIVTCDP--PEDISHGFLNGSSFNFDDLVEYICFPGYE--IAGSPILRCTADGTWIGEVPQCRPCMCNP-PVLKFGAVLGRDHTCGASIWFR-CDEGYKTLGPTEAVCDKG--------GVWSPGVPICSRGRCSTPPPAVPNAVVTGGATTGETVTYGCRPGYSLRGHPNLSCGRLGRWGVPSLHCDPVSCGEPPPVPNAMIVGSAFTYGSKAQYKCSEGFEPVTQTDSVHC---QSDGTW-----SKHSVRCRP------KPCSLPSNLTNVVVAGDQLTPVGGTITISCKPGFYLEGPGLSECGLFGRWSPSFSSNSCVLVFCD-KPHPLLHGIIKGESYSYGDTVTYTCLPGF--ELQGDAVQI--------CQGDKKWSGAQPLCVVVSCGPPPSVENAVSLMTGESYESKVT-------------YVCDSGLELIGPQNLTCQANGSWSLP-TPTCE 3336 HSP 8 Score: 86.2705 bits (212), Expect = 7.318e-17 Identity = 125/551 (22.69%), Postives = 191/551 (34.66%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKII------CQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFA-----------------KVAYEAT------THGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNW-TKMPTEGCQXXX----XXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWS 1916
VC ++ C PP G + + G + Y+C +G+ L+ CQA+ S PEC IP H + + + + + C+ GY+ S ++ +G W C C +D NG Y+ +S+ C G++++ C G W + C I C P +NG V G + + C G+ L G + C G W S TC +CG PP I F K+A + + HG +Y+C S + G L C E +G P C P + ++ N + + G+ V C GYEL + C +G WN PRC+ C P + V S + Y CH G+ + G E+ + D G W K P+ C+ NG+ Y G+ R+V + C+P + L G +VCL N WS
Sbjct: 2381 VCKQV--SCGPPPDVSFGDPSSASFYFGSVITYSCMAGFTLRKEASVSCQADGSWSKPYPEC------------IPVECPHPEEIPNGIVDVQGLMYLSTALYSCKPGYDLVGNSTVLCGQSG-LWIGGVPACHPIECPPPKDIPNGSAKYSRLQFSRSVTYS-CQRGYRLEGPE--------TLTCLESGNWDKEVPSCQQIYCSPPKPIDNGFVEGRDHKFGVTIFYSCFPGFLLMGQNHLTCEEHG-WSSSVPTCSPADCGLPPHIDFGDYFKIRDPSAELSGGDNKLAGQRSPTDTSFLHGTMVQYRCHSGYDMNGGV-VLGCQEDGIWNGTAPV--------CVPAECEAPP------NPEHGLAILTDTVLGSLVEYSCEEGYELEGQTVRQCVSGRQWNDEAPRCIPINC-GDPGGISNGEVVGRSFYFKEVIHYECHAGFIL----QGSESRTCQMD-----GKWDGKAPS--CRAVSCGHPVISNDVQVNGDSYTFGK----------------RLV-FSCNPGFILHGAATSVCLANSTWS 2862 HSP 9 Score: 84.3445 bits (207), Expect = 2.707e-16 Identity = 97/417 (23.26%), Postives = 153/417 (36.69%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGS-WN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
+ +C+ P P +G A + ++G VEY+C+ GY L+G R C + + + P C C I +V S F E + C G+ + +G +W C SCG N + ++YT+ + CN GF + C A+ WS T C C NG G N T++C GY L G+ C +G WD C + C PP +I + + EY C + G + L C G +P+ P C+ C P + V ++ T G + +C+ GY+ C G W+ +P C CS PP++ + V + +++ Y C GY +
Sbjct: 2695 VPAECEAPPNPEHGLAILTDTVLGSLVEYSCEEGYELEGQTVRQCVSGRQWNDEAPRCIPIN--CGDPGGISNGEVVGRS----FYFKEVIHYECHAGFILQGSESRTCQMDG-KWDGKAPSCRAVSCGHPVI-SNDVQVNGDSYTFGKRLVFSCNPGFILHGAATSV--------CLANSTWSESTPKCLPADCGRPPIIRNGHARGTNYGYNGKVTYECDVGYTLIGNPSLVCRGDGLWDDPPPRCDIVTCDPPEDISHGFLNGSSFNFDDLVEYICFPGYEIAG-SPILRCTADGTWIGEVPQCRP-CM--CNPPVLKFGAVLGRDH------------TCGASIWFRCDEGYKTLGPTEAVCDKGGVWSPGVPICSRGRCSTPPPAVPNAVVTGGATTGETVT-YGCRPGYSL 3078 HSP 10 Score: 71.633 bits (174), Expect = 2.308e-12 Identity = 63/198 (31.82%), Postives = 85/198 (42.93%), Query Frame = 3
Query: 750 KCEKKSCGKLEDPKNGRTMYNN-NYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEV----MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGW--LPKPEPKCL 1322
C+ C L P+NG + N N Y S C GF++Q ++ R CQADG WSG ICT CP LSPP++GE+ G + + +C +GY+L G C W G C+ C P IV +K H + C R+ G T LTC + G+ L PE +CL
Sbjct: 368 SCQAVVCAVLYPPENGFFIQNVCNNQYNSACGVRCMPGFELQGSS--------IRLCQADGTWSGAPPICTVRSCPVLSPPQHGELNCSEGGSPYRLECV--VRCLQGYRLEGRAKLTCLSSSQWSGPPPRCVEVRC---PSIVPSK-------HMRVSPPVCGERALRSGATCRLTC-----RRGYSLLGNPEVRCL 540 HSP 11 Score: 57.3806 bits (137), Expect = 6.397e-8 Identity = 52/191 (27.23%), Postives = 78/191 (40.84%), Query Frame = 3
Query: 945 TAICTAILCPELSPPENGEVMG--VWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG--PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN 1502
T+ C A++C L PPENG + N NS +C G++L GS +R C +G W G+ C VR+C PP+ + + + + +C L G LTC SG P P+C+ P V S + + + + G R C GY L + C +G W+
Sbjct: 366 TSSCQAVVCAVLYPPENGFFIQNVCNNQYNSACGVRCMPGFELQGSSIRLCQADGTWSGAPPICTVRSCPVLSPPQHGELNCSEGGSPYRLECVVRCLQGYRLEGRAK-LTCLSSSQWSG----PPPRCVEVRCPSIVPSKHMRV-----SPPVCGERALRSGATCRLTCRRGYSLLGNPEVRCLPSGDWS 546 HSP 12 Score: 55.8398 bits (133), Expect = 1.573e-7 Identity = 80/338 (23.67%), Postives = 121/338 (35.80%), Query Frame = 3
Query: 1041 FKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL------------LHCKPFQVDSAKV------YIHENNKTTNFIM-----HDEVTH--------GTHVRAKCNFGYEL-NSDILPACYNGSW-NFIPRCVEAACSARPPSM-KYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKG-NWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWSPPQMPTCEFI 1946
F C GY L G ++ C G W + C NCG PP + + E G+ EY+C+ L+GE+ N W P P CL H D + + Y + T + H + H G+ V C GYEL S L G+W P C +C+ PP++ ++ ++ + + S + C GY L +I+C W+ P CQP C +PP + E L ++ + Y C YRL+G C + G W+ P +P C +
Sbjct: 1658 FSCNPGYYLVGEPVQHCQNRGAWSHAAPQCERVNCGAPPPLEHGQYHGEDFYAGSSVEYQCRPGFYLLGESKM----HCANSGKWAGNP-PACLDVDECALGSDCDEHASCQNTDGSHICTCIYPYTGDGRNCTEPVKCKDPGHPDFGHREGTVFIVGSEVVFSCEEGYELIGSSRLSCSETGTWEGLFPFCKALSCN--PPTVPEHGILKGTNFTYRSKVTFSCEKGY----------ILEGTMEIQCESNLKWSSEPPI-CQPVTCGEPPAVDHAEFTLNNT-------------VYLSTLAYTCVEGYRLQGSGELQCESTGEWTSP-VPVCTRV 1963
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Match: csmd3a (CUB and Sushi multiple domains 3a [Source:ZFIN;Acc:ZDB-GENE-050419-118]) HSP 1 Score: 124.02 bits (310), Expect = 1.376e-28 Identity = 114/425 (26.82%), Postives = 159/425 (37.41%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHL--RKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSA--RPPSMKYSTV-RFLSLKHDSLARYYCHFGYYI 1631
C+ +D C P P NG + G V Y+C G LKG R CQ N S P C+ + P +P H + DF+ V C GY S + NG W C+ CG P NGR + T+ I C +G+ + +T RQCQA+G WSG CT I C + P NG G T+ TF C+ GY + CT G W C C PP I + G Y C S + + LTC SG +P+ C P V H + +FI EV+ C+ Y C +G+W+ F PRC+E + P + +Y ++ R K S+ ++C G+ +
Sbjct: 2778 CIVVD--CGHPGSPPNGVLSGEKFTFGSTVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGVP---SHGSREESDFRIRSKVHFTCATGYVLFGSSERMCFPNGT-WSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMEGYLLTGST--------TRQCQANGTWSGTAPNCTMINCGDPGVPANGVRYGEDFTIVQNITFACQPGYTMEADSFPTLTCTGNGTWSAPVPFCKAVTCTAPPPISNGLLEGSDFEWGTSVSYSC-SPGYELSFPAILTCVGNGTWSGEVPQ--------CLPKFCGDPGVPGHGFREGRSFIYQSEVSF------SCSPPYIPVGSATRFCQADGTWSGFQPRCIEPTRTTCENPGTPRYGSMNRTFGFKVGSMVAFHCQPGHLL 3173 HSP 2 Score: 118.627 bits (296), Expect = 7.344e-27 Identity = 127/442 (28.73%), Postives = 179/442 (40.50%), Query Frame = 3
Query: 657 VKIICQNGYEDPYKSHIIAK---CNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI--CTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKH-----DSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCE 1940
V+ C GY KS + K +W C+ SCG + P NG + +Y+ + FCNDG+++ + CQ DG WS I C+ I C EL P +G+ +G T + F C GY L GS +R+C G W G+ + C+ +CG P +IV +V E + Y+C LIG +S C + N SG LP C P I+ F ++D V+ CN GY + + C N W+ P C CS P + +++R ++H ++ Y C+ GYY+ G L+ C G W K P C C P +P NG L G+ K V+Y C +LKG C LNGHWS P MP C
Sbjct: 2445 VRWACDRGYRLIGKSTAVCKKTPYGYYDWDAPVPACQAVSCGVPKAPVNGGVL-AVDYSVGTRVTYFCNDGYRLS------SKELTSAVCQPDGTWSNHNKIPRCSVISCGELPTPASGKKIGTQTTFGATAIFTCDIGYMLVGSTVRECLSSGLWSGTETRCLGGHCGLPEQIVNGQVIGENFGYRDTVVYQCAPGFRLIG-SSVRICQQDHNWSGQLPI--------CVPISCGHPGSPIYGRTIGNGFNLNDVVSF------SCNTGYVMEGPVRAQCQANRQWSQPPPTCKVVNCSD--PGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLF----GSPVLT------CQPTGQWDK-PLPECIVVDCGHPGSPPNG--VLSGE-----------KFTFGSTVRYSCTGGRQLKGESSRTCQLNGHWSAP-MPFCS 2837 HSP 3 Score: 102.449 bits (254), Expect = 8.146e-22 Identity = 108/444 (24.32%), Postives = 169/444 (38.06%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY---NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + + C P P+ G + + D V ++C +GY ++GP + CQAN + S P C + C S P IP + + +F G V C GY + S ++ +W +C CG P NG + +T+ S C G +++ R CQ +G WS C ++ C + P +G + S F C GY L GS R C G W G+ +C CG P +V + TT Y C L G T+ C SG P C +++C V + V E +F + +T C GY + +D P NG+W+ +P C C+A PP + + + + Y C GY ++
Sbjct: 2642 VRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNTGYVMEGPVRAQCQANRQWSQPPPTC--KVVNC-SDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYL-FGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNG-VLSGEKFTFGSTVRYSCTGGRQLK--------GESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGVPSHGSREESDFRIRSKVHFTCATGYVLFGSSERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMEGYLLTGSTT-RQCQANGTWSG----TAPNCTMINCGDPGVPANGVRYGE-----DFTIVQNITF------ACQPGYTMEADSFPTLTCTGNGTWSAPVPFCKAVTCTA-PPPISNGLLEGSDFEWGTSVSYSCSPGYELSF 3055 HSP 4 Score: 94.7449 bits (234), Expect = 1.711e-19 Identity = 135/533 (25.33%), Postives = 188/533 (35.27%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYAL--KGPRKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG----PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCV--EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKC-NKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
+ C P PVNG VG +V Y C GY L K CQ + S P C+ + C P T G C GY + +C + W +C CG E NG+ + N+ Y+ + C GF++ ++ R CQ D WSG IC I C P G +G +N + +F C GY + G +C W TC V NC P I +K+ + T G Y C L G + LTC +G KP P+C++ VD H + + ++ T G+ VR C G +L + C NG W+ +P C + P + + + S + C GY + + M C G W+ C+P +C P TP NG +Y L D T + I Y C Y L G C NG WS P C I
Sbjct: 2483 VSCGVPKAPVNGGVLAVDYSVGTRVTYFCNDGYRLSSKELTSAVCQPDGTWSNHNKIPRCSVIS--CGELP----TPASGKKIGTQTTFGATAIFTCDIGYM--LVGSTVRECLSSGLWSGTETRCLGGHCGLPEQIVNGQVI-GENFGYRDTVVYQCAPGFRLIGSS--------VRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNTGYVMEGPVRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFG-SPVLTC----QPTGQWDKPLPECIV------VDCG----HPGSPPNGVLSGEKFTFGSTVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGVPSHGSREESDFRIRSKVHFTCATGYVLFGSSERM----------CFPNGTWSGT-QPSCKPVQCGNPGTPSNGRVYRL---DGTTFSHSVI---------YSCMEGYLLTGSTTRQCQANGTWS-GTAPNCTMI 2959 HSP 5 Score: 93.9745 bits (232), Expect = 3.487e-19 Identity = 142/573 (24.78%), Postives = 203/573 (35.43%), Query Frame = 3
Query: 294 ACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNG---RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC---IVRNCGPPPEIVFAKVAYEATTHGAQAE--YKCKSRSTLIGETSFLTCGEVDNK---SGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYSTVR----FLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTC 1937
TA C + Y + C+ G + C P Q VNG D V Y C G+ L G R CQ + SG P C + C P + ++ + + F + V C GY E P + A+C N +W P C+ +C P N + + N+T+ ++ CN G+ + + CQ G+W C + C P NG + G T S + C G QL G R C G+W C CG P +HG++ E ++ +S+ T ++ G + +G +P CKP Q + N + D T V C GY L C NG+W+ P C C P + + VR F +++ + A C GY + D TL+ G W+ P C+ CT PP NG LL SD T V Y C P Y L P I C+ NG WS ++P C
Sbjct: 2566 GATAIFTCDIGYMLVGSTVRECLSSGLWSGTETRCLGGHCGLPEQIVNGQVIGENFGYRDTVVYQCAPGFRLIGSSVRICQQDHNWSGQLPICVPIS--CGH----PGSPIYGRTIGNGFNLNDVVSFSCNTGYVMEGPVR----AQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSP--------VLTCQPTGQWDKPLPECIVVDCGHPGSPPNGVLSGEKFTFGSTVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDP----------GVPSHGSREESDFRIRSKVHFTCATGYVLFGSSERMCFPNGTWSGTQPS----CKPVQCGNPGT--PSNGRVYRL---DGTTFSHSVIYSCMEGYLLTGSTTRQCQANGTWSGTAPNCTMINCGD--PGVPANGVRYGEDFTIVQNITFA---CQPGY--TMEADSFPTLTCT-----GNGTWSA-PVPFCKAVTCTAPPPISNG---LLEGSDFEWGTS----------VSYSCSPGYELSFPAILTCVGNGTWS-GEVPQC 3074 HSP 6 Score: 88.5817 bits (218), Expect = 1.342e-17 Identity = 130/529 (24.57%), Postives = 194/529 (36.67%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPEN----GEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKG---PKIAVCLNGHWSPPQMPTCEFI 1946
+ C P +G + G +TC GY L G R C ++ SG+E C C +P V+ ++F + V C G+ S I + + N PI C SCG P GRT+ N + + CN G+ ++ R QCQA+ +WS C + C + P N ++ T ++ + C GY L GS + C G WD CIV +CG P ++ E T G+ Y C L GE+S TC +G P P C D V H + + ++F + + V C GY L C+ NG+W+ P C C P + + + + H + Y C GY + T ST + N G W+ C C P P NG Y + + N + + C P Y ++ P + NG WS P +P C+ +
Sbjct: 2545 ISCGELPTPASGKKIGTQTTFGATAIFTCDIGYMLVGSTVRECLSSGLWSGTETRCLGGH--C----GLPEQIVNGQVIGENFGYRDTVVYQCAPGFRLIGSSVRICQQDHNWSGQLPI-CVPISCGHPGSPIYGRTI-GNGFNLNDVVSFSCNTGYVME--------GPVRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGVLSGEKFTFGSTVRYSCTGGRQLKGESS-RTC----QLNGHWSAPMPFCSGDSSGTCGDPG-VPSHGSREESDFRIRSK------VHFTCATGYVLFGSSERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVI--YSCMEGYLL--------TGSTTRQCQAN-GTWSGT-APNCTMINCGDPGVPANGVRY-----------GEDFTIVQN--ITFACQPGYTMEADSFPTLTCTGNGTWSAP-VPFCKAV 3019 HSP 7 Score: 82.4185 bits (202), Expect = 1.205e-15 Identity = 88/347 (25.36%), Postives = 127/347 (36.60%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPR--KRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQ----VDSAKVYIHENNKTTNFI 1397
+ C P P NG + + + C+ GY ++ C N S P C T C + P I + + DF+ G V C GYE + + I C GN W + +C K CG P +G ++ YQS C+ + R CQADG WSG C T C P G + + V S+ F C+ G+ L GS R C + W GS CI NC P V + +G Y C++ L G + C +G +P L KP + S K+ + ++ N+I
Sbjct: 2959 INCGDPGVPANGVRYGEDFTIVQNITFACQPGYTMEADSFPTLTCTGNGTWSAPVPFCKAVT--CTAPPPISNGLLEGS----DFEWGTSVSYSCSPGYELSFPA--ILTCVGNGTWSGEVPQCLPKFCGDPGVPGHGFRE-GRSFIYQSEV--------SFSCSPPYIPVGSATRFCQADGTWSGFQPRCIEPTRTTCENPGTPRYGSMNRTFGFKVGSMVAFHCQPGHLLQGSTTRLCQADLTWSGSQPECIPHNCKQPESPPHVDVIGMDLPGYGYTLIYTCQTGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYI 3288 HSP 8 Score: 57.3806 bits (137), Expect = 5.770e-8 Identity = 51/208 (24.52%), Postives = 80/208 (38.46%), Query Frame = 3
Query: 345 CVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD-DFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
CV + G V + C P P +G + +V ++C Y G R+CQA+ SG +P C + T P P + + NR FK G V CQ G+ + C + W +C +C + E P + + + Y I C GF + ++ R C++DG W+G +C A
Sbjct: 3061 CVGNGTWSGEVPQCLPKFCGDPGVPGHGFREGRSFIYQSEVSFSCSPPYIPVGSATRFCQADGTWSGFQPRCIEPTRTTCENPGTPR---YGSMNRTFGFKVGSMVAFHCQPGHL--LQGSTTRLCQADLTWSGSQPECIPHNCKQPESPPHVDVIGMDLPGYGYTLIYTCQTGFFLSGGSEH-------RVCRSDGTWTGKMPVCRA 3256
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:HGNC Symbol;Acc:HGNC:14026]) HSP 1 Score: 116.316 bits (290), Expect = 3.840e-26 Identity = 91/305 (29.84%), Postives = 123/305 (40.33%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNR--DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPK----NGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI---LCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKC 1223
++C D G + + + C P P NG N S + D V +TC SGY L G + C+ N + S P C + C S P V ++ R + F V C+ G+ S + + NG W KC SCG P GR N + S C+ + N RQCQ DG+WSG C+ + LC + P +G +G V S+ F C+ GY L GS R C + G+W G C V CG PP I F KV G+ Y C
Sbjct: 2679 VRICQQDHRWSGQAPVCVPITCGHPGNPSNGRTNGSEFNLNDVVNFTCSSGYVLHGTSRAQCRMNGQWSNPLPVC--KVVNC-SDPGFVENAVRHSAQRYPESFSYTHSVMFHCKRGFYLLGSSVLTCQSNG-LWDRSLPKCLFISCGDPGTPPFAVLTGRKFTNGALVHYS-------------CSQGRTVVGNSTRQCQEDGRWSGSPPYCSGMNPGLCGDPGVPPHGSRLGEEFRVRSLLRFTCEAGYVLLGSAERTCLQNGSWSGVQPVCEVITCGQPPAIRFGKVEGSDLQWGSSVAYSC 2966 HSP 2 Score: 103.99 bits (258), Expect = 2.242e-22 Identity = 101/400 (25.25%), Postives = 155/400 (38.75%), Query Frame = 3
Query: 453 VGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIK-----TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
+G QV +C GY L G R C N G E + + +T C S P T H + + ++ + V C G+ S I + + + W C +CG +P NGRT + + + C+ G+ + T+ R QC+ +G+WS +C + C + EN S F CK G+ L GS + C G WD S C+ +CG P FA + T+GA Y C T++G ++ C E SG P P V H + + +E + +R C GY L C NGSW+ + E +PP++++ V L+ S Y C GY ++
Sbjct: 2600 LGAQVMLSCTPGYYLGGRRTIKCLPNATWGGLEEKSSCKTGHCDSPD--PITNGHISGDGSSYR--DTVVYQCNLGFRLIGTSVRICQQD-HRWSGQAPVCVPITCGHPGNPSNGRTN-GSEFNLNDVVNFTCSSGYVLHGTS--------RAQCRMNGQWSNPLPVCKVVNCSDPGFVENAVRHSAQRYPESFSYTHSVMFHCKRGFYLLGSSVLTCQSNGLWDRSLPKCLFISCGDPGTPPFAVLTGRKFTNGALVHYSCSQGRTVVGNST-RQCQEDGRWSG-----SPPYCSGMNPGLCGDPGVPPHGSR------LGEEFRVRSLLRFTCEAGYVLLGSAERTCLQNGSWSGVQPVCEVITCGQPPAIRFGKVEGSDLQWGSSVAYSCFDGYQLS 2973 HSP 3 Score: 92.4337 bits (228), Expect = 8.909e-19 Identity = 89/333 (26.73%), Postives = 128/333 (38.44%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAIL---CPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP--KPEPKCLLHCKPFQVDSAKVYIHE 1373
C P P +G V + +TC++GY L G +R C N SG +P C + C P I + +V + D + G V C +GY+ S IA C GN W+ + +C CG P G N++TY+S +C F + + RR CQ DG W+G C C + P G + V S F+C++ Y + GS R C W G C+ C P V A + T G Y C+ L G + TC SG P K ++ F ++S +E
Sbjct: 2882 CGDPGVPPHGSRLGEEFRVRSLLRFTCEAGYVLLGSAERTCLQNGSWSGVQPVC--EVITCGQPPAIRFGKVEGS----DLQWGSSVAYSCFDGYQ--LSSPGIATCEGNGTWRGEIPQCLPVLCGDPGTPAEGYRE-GNHFTYKSEVAFYCRSPFLLVGSP--------RRVCQEDGSWTGIQPSCIDPAYNACKDPGTPAYGIPLQAQGFEVGSKVFFRCRKNYHILGSTTRTCLENLTWSGMQPECVAHACRQPETPSHVDVRAIDLPTLGYTLMYMCQDGFFLAGGSEHRTCRPDGRWSGKPPVCKASDTLIVPADVFSLNSGWTGFYE 3197 HSP 4 Score: 73.559 bits (179), Expect = 6.234e-13 Identity = 117/518 (22.59%), Postives = 190/518 (36.68%), Query Frame = 3
Query: 456 GDQVEYTCKSGYALKGPRKRYCQ--ANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWK--YDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQ--CTTDQFEDKNCRRQCQADGKWSG--DTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPT--EGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELP 1964
G +++Y C GY L G R C+ N P Q C +P + + + + + G +V+ C GY+ + + A C W P +C C +E +M + + ++ I+ G ++ CT + +C + W G + + C C P NG + G ++ ++C G++L G+ +R C ++ W G C+ CG P + + C S L G TS C +G P P C +++C D V + + TH K F Y L S +L NG W+ +P+C+ +C P + ++ + + +L Y C G + G T +C + G W+ P G P C P P +G LG+ R R ++++ C Y L G CL NG WS Q P CE I + P
Sbjct: 2472 GSRIQYYCNPGYRLVGQRNATCRLHPNGLYQWDTPAPLCQAISC----GVPDSPANGSFHGLQYTVGSNVQYQCDEGYQPESAALLSAVCLEDGTWSNAARPTQCLPVQCPNIE------SMLSEHMVWRLISGSLNELGAQVMLSCTPGYYLGGRRTIKCLPNATWGGLEEKSSCKTGHCDSPDPITNGHISGDGSSYRDTVVYQCNLGFRLIGTSVRICQQDHRWSGQAPVCVPITCGHPGNPSNGRTNGSEFNLNDVVNFTCSSGYVLHG-TSRAQC----RMNGQWSNPLPVCKVVNCS----DPGFVENAVRHSAQRYPESFSYTHSVMFHCKRGF-YLLGSSVLTCQSNGLWDRSLPKCLFISC-GDPGTPPFAVLTGRKFTNGALVHYSCSQGRTVV----GNSTR------QCQEDGRWSGSPPYCSGMNPGLCGDPGVPPHGS--RLGEEFRVR-----------SLLRFTCEAGYVLLGSAERTCLQNGSWSGVQ-PVCEVITCGQPP 2944
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Match: csmd2 (CUB and Sushi multiple domains 2 [Source:ZFIN;Acc:ZDB-GENE-030616-39]) HSP 1 Score: 112.079 bits (279), Expect = 7.029e-25 Identity = 122/502 (24.30%), Postives = 184/502 (36.65%), Query Frame = 3
Query: 396 QCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-CNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTY-QSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA-------LRKDGMETLSTIFDIKCNK------GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRV 1841
+C P PV+G G V ++C+ GY L+G +R C N G++PEC + P Q HD + C+ GY Y + ++ + C N W D +C +CG P NG + +++TY +S++ Q C+ GF + D+ C D W+ +C AI+C NG+VMG S ++ C +GYQL + C GNW G C CG P + T+ + + C L+G T G +P C+ VD N T + + G+ V C GY L I C N +W+ + P C+ CS P + SL + + Y C G+Y+A R DG T N+ G + P Q + G LG+ L+ + +P NRV
Sbjct: 2897 RCGDPGIPVHGIRLGEEFSSGSVVRFSCEPGYVLRGSSERTCLPNGTWQGTQPECQVVSCGNPGTPRNAQIQFHDG-----LVFSRSITYACREGY---YSTGLLTRHCTVNGTWTGDMPECTVINCGDPGVPANGLRL-GSDFTYSRSVSFQ-CSPGFTMDA------DRASTLICTKDRTWNSTKPVCKAIVCGAPPSIPNGQVMGTDFQWGSSISYTCNQGYQLSLPTILTCQGSGNWSGEKPQCFPVFCGDPGIPAQGRREDRGFTYLSSVSFSCFPPLVLVGSTR-----RYCQYDGTWSGTQPSCIDPSHTSCVDPGTPLFGYQNNTQGYQI------GSTVFYSCRKGYLLLGSISRTCLPNLTWSGMQPECIAHHCSQPELPAQADARAIELPSLGYTLI--YTCQPGFYLAGGSEHRTCRADGSWTGKPPLCAADNRPSGKTVGTVQEPPNTKLQGNGVFAKNSLWRGSYEYLGKKQPAMLSITAFEPFSNRV 3369 HSP 2 Score: 105.916 bits (263), Expect = 5.588e-23 Identity = 107/431 (24.83%), Postives = 176/431 (40.84%), Query Frame = 3
Query: 417 PVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCN---------------GNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG--EVMGVWNTVNSIKT---FKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLA-----RYYCHFGYY 1628
P NG+ ++ + G ++C +GY L G R R C +N SGSE +C L + ++ ++ + D NG+ II +N Y Y+ ++ +CN + W C +CG +P NG T + N + + CN G+ +Q + CQ +G+WS C + C E EN +V+ S +T + C GY L G+ + C +G WD S C++ C P +A+++ + T G+ Y C + +++G T+ + ++D + W P HC DS+ + +E + G+ VR C GY L C NG+W P C +C P + + + ++F HD L Y C GYY
Sbjct: 2592 PPNGNKIGTLTVYGATAIFSCNTGYTLVGTRVRECMSNGLWSGSEVQCLGHHLLVCA--WVFFSLAGHCGSPDPIVNGQ---IIGEN-YN--YRGSVVYQCNPGFRLIGVSVRICEQDHRWSGKAPVCVPITCGHPGNPANGVT-HGNQFNLNDVVRFACNTGYVLQGAV--------KSHCQPNGQWSNALPRCKIVNCTEPGHVENSVRQVLSSGPHRYSFQTTVSYTCNPGYYLLGTSILTCQGDGTWDRSLPKCLLVLCDHPSMPPYAQISGDRRTVGSVIRYSCMGQRSIVGNTTRMC--QLDGQ--WSGSPP-----HCT---GDSSGRCGDPGIPVHGIRLGEEFSSGSVVRFSCEPGYVLRGSSERTCLPNGTWQGTQPECQVVSC-GNPGTPRNAQIQF----HDGLVFSRSITYACREGYY 2988 HSP 3 Score: 96.6709 bits (239), Expect = 4.895e-20 Identity = 137/596 (22.99%), Postives = 205/596 (34.40%), Query Frame = 3
Query: 399 CQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYC----QANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNG---------RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC--------------IVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSW-NFIPRCVEAACSARPPSMKYSTVRFLS-----LKHDSLARYYCHFGYY------IALRKDGM--ETLSTIFDIKCNKGNWTKMP----TEGCQXXXXXXXXXXXNGEIYLLGQSDRT--------------------RLTDKSIKPIH----------NRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
C PP PVNG + + +G + ++C G+ L G C Q + + P C Q C +P V+ + DF G V C G+ + C ++ P++ + C + P G R +Y Y+++ + C+ G+ F +CQA W C I C +L P NG +G + F C GY L G+ +R+C G W GS C + +CG P IV ++ E + Y+C LIG S C + SG P C P H N ++ VR CN GY L + C NG W N +PRC C+ P ++ S + LS + Y C+ GYY + + DG +L + C+ MP G + + G+ ++G + R R D I P+H VV++ C P Y L+G CL NG W Q P C+ +
Sbjct: 2396 CSPPNPPVNGSVHSQTGTKLGSTLRFSCDQGFRLIGQSSATCTRSPQGIYQWNAPVPLC--QVVSC----GMPIAPVNGSVVGQDFTLGSRVTFRCNPGFRLANTVPLSTVCQ-ESGRWTPVETPPR-CIPVTCPDIGHSAVEHGRWRLIYGMQNQYEAMMMLTCDPGY--------FYKGQRVIRCQASSAWDYPEPRPACEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGTRVRECMSNGLWSGSEVQCLGHHLLVCAWVFFSLAGHCGSPDPIVNGQIIGENYNYRGSVVYQCNPGFRLIG-VSVRICEQDHRWSGKAPV--------CVPITCG------HPGNPANGVTHGNQFNLNDVVRFACNTGYVLQGAVKSHCQPNGQWSNALPRCKIVNCT-EPGHVENSVRQVLSSGPHRYSFQTTVSYTCNPGYYLLGTSILTCQGDGTWDRSLPKCLLVLCDH---PSMPPYAQISGDRRTVGSVIRYSCMGQRSIVGNTTRMCQLDGQWSGSPPHCTGDSSGRCGDPGI-PVHGIRLGEEFSSGSVVRFSCEPGYVLRGSSERTCLPNGTWQGTQ-PECQVV 2954 HSP 4 Score: 92.8189 bits (229), Expect = 7.890e-19 Identity = 109/452 (24.12%), Postives = 169/452 (37.39%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNG-------EDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICT---AILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLT--CGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSD---ILPACYNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P NG + + + D V + C +GY L+G K +CQ N + S + P C + C ++ +NS R +G V C GY S I C G+ W KC C P + + + T S+ + C + N R CQ DG+WSG CT + C + P +G +G + S+ F C+ GY L GS R C G W G+ C V +CG P A++ + + Y C+ T LT C +G +P+ C V + + T+ V +C+ G+ +++D L + +WN P C C A PPS+ V + S Y C+ GY ++L
Sbjct: 2695 VRICEQDHRWSGKAPVCVPITCGHPGNPANGVTHGNQFNLNDVVRFACNTGYVLQGAVKSHCQPNGQWSNALPRC--KIVNCTEPGHV------ENSVRQVLSSGPHRYSFQTTVSYTCNPGYYLLGTS--ILTCQGDGTWDRSLPKCLLVLCDHPSMPPYAQ-ISGDRRTVGSV--------IRYSCMGQRSIVGNTTRMCQLDGQWSGSPPHCTGDSSGRCGDPGIPVHGIRLGEEFSSGSVVRFSCEPGYVLRGSSERTCLPNGTWQGTQPECQVVSCGNPGTPRNAQIQFHDGLVFSRSITYACREGYY---STGLLTRHCTVNGTWTGDMPE--------CTVINCGDPGV------PANGLRLGSDFTYSRSVSFQCSPGFTMDADRASTLICTKDRTWNSTKPVCKAIVCGA-PPSIPNGQVMGTDFQWGSSISYTCNQGYQLSL 3109 HSP 5 Score: 79.7221 bits (195), Expect = 8.599e-15 Identity = 136/560 (24.29%), Postives = 190/560 (33.93%), Query Frame = 3
Query: 381 MEIDLQCQPPVQPVNGHA----NHSILLVGDQVEY------TCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKN--GEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCE--------------KKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEI------VFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSAR--PPSMKYSTVRF-LSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
+E +C P P GH+ L+ G Q +Y TC GY KG R CQA+ EP + C P N N+ G C GY + +C N W ++C CG + NG+ + NY Y+ + CN GF++ + R C+ D +WSG +C I C P NG G +N + F C GY L G+ C G W + C + NC P + V + + + Y C L+G TS LTC G + PKCLL + H + I D T G+ +R C + + C +G W+ P S R P + +R S+ R+ C GY LR T G W E CQ C P TP+N +I + D + +R + Y C Y G C +NG W+ MP C I
Sbjct: 2510 VETPPRCIPVTCPDIGHSAVEHGRWRLIYGMQNQYEAMMMLTCDPGYFYKGQRVIRCQASSAWDYPEPRPACEIISCGDLGTPP------NGNKIGTLTVYGATAIFSCNTGYT--LVGTRVRECMSNGLWSGSEVQCLGHHLLVCAWVFFSLAGHCGSPDPIVNGQII-GENYNYRGSVVYQCNPGFRLIGVS--------VRICEQDHRWSGKAPVCVPITCGHPGNPANGVTHGNQFNLNDVVRFACNTGYVLQGAVKSHCQPNGQWSNALPRCKIVNCTEPGHVENSVRQVLSSGPHRYSFQ-TTVSYTCNPGYYLLG-TSILTC----QGDGTWDRSLPKCLL----------VLCDHPSMPPYAQISGDRRTVGSVIRYSCMGQRSIVGNTTRMCQLDGQWSGSPPHCTGDSSGRCGDPGIPVHGIRLGEEFSSGSVVRFSCEPGY--VLRGSSERTC-------LPNGTWQGTQPE-CQVVSCGNPGTPRNAQI---------QFHDGL---VFSRSITYACREGYYSTGLLTRHCTVNGTWT-GDMPECTVI 3013
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Match: csmd3a (CUB and Sushi multiple domains 3a [Source:ZFIN;Acc:ZDB-GENE-050419-118]) HSP 1 Score: 104.76 bits (260), Expect = 1.463e-22 Identity = 138/534 (25.84%), Postives = 202/534 (37.83%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYAL--KGPRKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG----PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRC---VEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
+ C PV P NG + G + Y C G+ L K CQA+ S P CT S +P T + G C GY + +C + W C CG+ E NG+ + N+ Y+ + CN GF++ ++ R CQ D WSG C ++ C P G +G +N + F C +GY L G +C + W +C V NC P I +K+ + T G + C L G S LTC + G+ +P P+C+ +VD H ++ D+ T G+ VR C G EL D C +G W+ +P C V C P + ++T S + S R+ C G+ + + I G W+ + PT C+P C P +P NG + +R+ S + V Y C YRL G +CL NG WS + P C I
Sbjct: 2433 VSCGIPVAPGNGGVLAADYSAGTRATYFCNEGFRLSSKEVTSTVCQADGTWSSHNKIPRCT-----VISCGILP-TPPNGKKIGTQTTFGATAIFTCDAGYI--LVGSTVRECLASGLWSGTETSCLAGHCGEPERMVNGQVI-GENFGYRDTVVYQCNPGFRLIGSS--------VRICQQDHTWSGHLPSCVSVSCGHPGSPIYGRTVGDGFNLNDVVNFFCNDGYILEGPSQAQCQADRQWSQQPPSCRVVNCTDPGIPANSIRKSKIEFGNFTFGTVVSFDCNPGFYLFG-ASVLTCQPL----GYWDRPLPECI------EVDCG----HPGVPPHGALIGDKFTFGSAVRYTCTGGRELIGDQGRTCQLSGQWSGSLPHCSGDVAGEC-GDPGTPAHATREEGSFQLRSKVRFTCATGHTLYGSAE---------RICFPNGTWSGRQPT--CKPVHCGNPGSPPNGRV--------SRIDGTSF----SHSVVYSCVDGYRLSGSPTRLCLANGTWSGSE-PNCTLI 2909 HSP 2 Score: 104.375 bits (259), Expect = 1.911e-22 Identity = 94/337 (27.89%), Postives = 137/337 (40.65%), Query Frame = 3
Query: 657 VKIICQNGYEDPYKSHIIAKCNGNE-----WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAI--CTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIP---RCVEAACSARPP-SMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
V+ C GY+ KS +A C E W C+ SCG P NG + +Y+ + A FCN+GF++ + CQADG WS I CT I C L P NG+ +G T + F C GY L GS +R+C G W G+ ++C+ +CG P +V +V E + Y+C LIG +S C + SG LP C I+ F ++D V CN GY L C + W+ P R V P S++ S + F + ++ + C+ G+Y+
Sbjct: 2395 VRWACDRGYKLIGKS--MAVCRKTEFGFLTWDNSVPACQAVSCGIPVAPGNGGVL-AADYSAGTRATYFCNEGFRLS------SKEVTSTVCQADGTWSSHNKIPRCTVISCGILPTPPNGKKIGTQTTFGATAIFTCDAGYILVGSTVRECLASGLWSGTETSCLAGHCGEPERMVNGQVIGENFGYRDTVVYQCNPGFRLIG-SSVRICQQDHTWSGHLPS--------CVSVSCGHPGSPIYGRTVGDGFNLNDVVNF------FCNDGYILEGPSQAQCQADRQWSQQPPSCRVVNCTDPGIPANSIRKSKIEFGNFTFGTVVSFDCNPGFYL 2707 HSP 3 Score: 93.5893 bits (231), Expect = 4.133e-19 Identity = 106/478 (22.18%), Postives = 165/478 (34.52%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT-DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQF---------EDKNCR-------------------------------------------RQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-----YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY-CHFGYYIA 1634
C+E+D C P P +G G V YTC G L G + R CQ + + SGS P C+ D C P T H F+ V+ C G+ + I NG W C+ CG P NGR + ++ + C DG+++ + + + NC R C +G WSG C A+ CP +GEV G S ++C GY+L S C G+W G C+ + CG P AK ++ ++ Y C + L+G ++ + G +P+C+ + + N + F + G+ VR C G+ L C ++GS P C+ +C +P S ++ V + L Y C G+ +
Sbjct: 2728 CIEVD--CGHPGVPPHGALIGDKFTFGSAVRYTCTGGRELIGDQGRTCQLSGQWSGSLPHCSGDVAGECGD----PGTPAHATREEGSFQLRSKVRFTCATGHTLYGSAERICFPNGT-WSGRQPTCKPVHCGNPGSPPNGRVSRIDGTSFSHSVVYSCVDGYRLSGSPTRLCLANGTWSGSEPNCTLISCGDPGIPANGLRFGETFTIGHNVSYACQPGYLMENATSNTRTCTHNGTWSGTLPTCQAVTCPPPPSLAHGEVEGSVFQWGSSVGYRCLTGYELSFSAALTCVANGSWSGEVPLCMPKFCGDPGLPPQAKREGQSFIFKSEVLYSCSTPYLLVGSST-----RICQADGTWSGNQPRCIEPTRTTCENPGTPEYGSLNASLGFKV------GSTVRFHCQTGHLLLGSTTRTCQQDLTWSGSQ---PECIAHSCK-QPRSPPHANVLGMDLPAFGYTLLYSCQPGFMLT 3183 HSP 4 Score: 92.8189 bits (229), Expect = 6.511e-19 Identity = 82/310 (26.45%), Postives = 120/310 (38.71%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRK--RYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENGEV-MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
+ C P P NG +G V Y C+ GY ++ R C N SG+ P C Q C P + + +V + F+ G V C GYE + + + NG+ W + C K CG P + ++ ++S + C+T + R CQADG WSG+ C T C PE G + + V S F C+ G+ L GS R C ++ W GS CI +C P A V + G Y C+ L G + C + +G +P
Sbjct: 2909 ISCGDPGIPANGLRFGETFTIGHNVSYACQPGYLMENATSNTRTCTHNGTWSGTLPTC--QAVTCPPPPSLAHGEVEGSV----FQWGSSVGYRCLTGYELSFSAALTCVANGS-WSGEVPLCMPKFCGDPGLPPQAKRE-GQSFIFKSEVL--------YSCSTPYLLVGSSTRICQADGTWSGNQPRCIEPTRTTCENPGTPEYGSLNASLGFKVGSTVRFHCQTGHLLLGSTTRTCQQDLTWSGSQPECIAHSCKQPRSPPHANVLGMDLPAFGYTLLYSCQPGFMLTGGSEHRVCRPDGSWTGKVP 3202 HSP 5 Score: 92.8189 bits (229), Expect = 7.662e-19 Identity = 108/447 (24.16%), Postives = 169/447 (37.81%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--TDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPEL----SPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVA-YEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL---NSDILPACYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P+ G + D V + C GY L+GP + CQA+ + S P C + TD P IP + + +F G V C G+ S + + G W +C + CG P +G + + +T+ S C G ++ DQ R CQ G+WSG C+ + E +P G + + ++ F C G+ L+GS R C G W G TC +CG P +V+ + T+ Y C L G + L +G EP C L+ C + + + E T G +V C GY + S+ +NG+W+ +P C C PPS+ + V + S Y C GY ++
Sbjct: 2592 VRICQQDHTWSGHLPSCVSVSCGHPGSPIYGRTVGDGFNLNDVVNFFCNDGYILEGPSQAQCQADRQWSQQPPSCRVVNCTD-----PGIPANSIRKSKIEFGNFTFGTVVSFDCNPGFYLFGASVLTCQPLG-YWDRPLPECIEVDCGHPGVPPHG-ALIGDKFTFGSAVRYTCTGGREL--IGDQ------GRTCQLSGQWSGSLPHCSGDVAGECGDPGTPAHATREEGSFQLRSKVR-FTCATGHTLYGSAERICFPNGTWSGRQPTCKPVHCGNPGSPPNGRVSRIDGTSFSHSVVYSCVDGYRLSGSPTRLCL-----ANGTWSGSEPNCTLISCGDPGIPANGLRFGET-----------FTIGHNVSYACQPGYLMENATSNTRTCTHNGTWSGTLPTCQAVTCPP-PPSLAHGEVEGSVFQWGSSVGYRCLTGYELSF 3005 HSP 6 Score: 60.8474 bits (146), Expect = 5.621e-9 Identity = 49/214 (22.90%), Postives = 81/214 (37.85%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIP-YTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC 956
+ + A CV + G V + + C P P + +V Y+C + Y L G R CQA+ SG++P C + T P P Y ++ + FK G V+ CQ G+ C + W +C SC + P + + + + + C GF + ++ R C+ DG W+G +C
Sbjct: 3003 LSFSAALTCVANGSWSGEVPLCMPKFCGDPGLPPQAKREGQSFIFKSEVLYSCSTPYLLVGSSTRICQADGTWSGNQPRCIEPTRTTCENPGTPEYGSLNASLG---FKVGSTVRFHCQTGHL--LLGSTTRTCQQDLTWSGSQPECIAHSCKQPRSPPHANVLGMDLPAFGYTLLYSCQPGFMLTGGSEH-------RVCRPDGSWTGKVPVC 3204
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003364.1 (pep scaffold:Pmarinus_7.0:GL476462:338772:355022:-1 gene:ENSPMAG00000003078.1 transcript:ENSPMAT00000003364.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 108.612 bits (270), Expect = 4.772e-25 Identity = 133/526 (25.29%), Postives = 208/526 (39.54%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLV-GDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQ------LHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPE-----PKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SW-NFIPRCVEAACSARPPSMKYSTVRFLSLK-HDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLN-GHWS 1916
+ + C+ V+P NG + + V G Y C GY+L GP+ R C + S +P C + C P + + V + + F G+ V C++G+ ++HI +G W P KC + CG P++GR + +++T A C+ G+KI + C +DG+WS C + C P NG G T + T+ C EG + + + + C G W G TC + PP VA +Y R T+ T G +++ P P+C+ AK + FI +DEVT GT V CN GY+L C +W + IP C C A P +++ V ++ S A Y C G+ + ++ + + G W+ C KC P ++GE+ + DR L NRV+ Y CH L+GP + +C + G WS
Sbjct: 74 VLVTCKVLVEPENGFISVATEPVYGSVASYMCADGYSLVGPQLRRCMQDGIWSDIDPVCEALS--CPQPPDVANSAVVQMA-QGTFSLGDSVMYACRDGFSISGEAHITCLESGI-WSKPP-KCIDEDCGNPGSPRHGR-LEGSSFTEGDSATFVCDIGYKIG------GKDHINTTCDSDGRWSRPLQDCELLSCGSPQPILNGRWTGNL-TYGQVITYSCNEGVKFSDGIMVESTSIVVCQANGLWLGRPPTCERKQTCAPPLPRTHSVASLPPVKTLGRQYPGSPRGTVASLPPVKTSGRQQSETQKCPHTGLLGRFPRCV------TTRLAKTCPALSAPRDGFIENDEVTVGTVVIFGCNKGYKLAGKPTTECQPSLTWSSSIPSCQMVTCRAAP--LEHGRVNVTAVTPFGSAAAYDCDLGFVLVGQR---------VRVCLDTGEWSGS-NPHCHRIKCKTPLELQHGEVVV----DRENL---------NRVI-YVCHEGLVLEGPNVRMCTDAGTWS 554 HSP 2 Score: 71.2478 bits (173), Expect = 3.879e-13 Identity = 83/333 (24.92%), Postives = 125/333 (37.54%), Query Frame = 3
Query: 630 RDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVM----GVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYY 1610
R F E V C GY S+ I +C W C +C L +P+NG Y S+A C DG+ + Q R+C DG WS +C A+ CP+ N V+ G ++ +S+ + C++G+ + G C G W CI +CG P ++ + T G A + C + G+ T + D + W +P C LL C Q I T N +T+ + K + G + S + C NG W P E + PP + +V L +L R Y
Sbjct: 33 RQWFFLQELVSYHCNIGYTVSGFSYSI-RCVEGGWTKHKFSCVLVTCKVLVEPENGFISVATEPVYGSVASYMCADGYSL--VGPQL------RRCMQDGIWSDIDPVCEALSCPQPPDVANSAVVQMAQGTFSLGDSV-MYACRDGFSISGEAHITCLESGIWS-KPPKCIDEDCGNPGSPRHGRLEGSSFTEGDSATFVCDIGYKIGGKDHINTTCDSDGR--W-SRPLQDCELLSCGSPQ------PILNGRWTGNLTYGQVITYSCNEGVKFSDGIMVESTSIVVCQANGLWLGRPPTCERKQTCAPPLPRTHSVASLP-PVKTLGRQY 344 HSP 3 Score: 62.7734 bits (151), Expect = 1.609e-10 Identity = 67/272 (24.63%), Postives = 110/272 (40.44%), Query Frame = 3
Query: 921 ADGKWSGDTAICTAILCPELSPPENGEVMGVWNTV-NSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEAT---THGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSD--ILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMP 1712
+G W+ C + C L PENG + V S+ ++ C +GY L G LR+C ++G W + C +C PP++ + V A + G Y C+ ++ GE + +TC E SG KP PKC+ + H + ++F D T C+ GY++ I C +G W+ + C +C + P + +L + + Y C+ G + DG+ ST + G W P
Sbjct: 62 VEGGWTKHKFSCVLVTCKVLVEPENGFISVATEPVYGSVASYMCADGYSLVGPQLRRCMQDGIWSDIDPVCEALSCPQPPDVANSAVVQMAQGTFSLGDSVMYACRDGFSISGE-AHITCLE----SGIWSKP-PKCIDE----DCGNPGSPRHGRLEGSSFTEGDSATF------VCDIGYKIGGKDHINTTCDSDGRWSRPLQDCELLSCGSPQPILNGRWTG--NLTYGQVITYSCNEGVKFS---DGIMVESTSIVVCQANGLWLGRP 312 HSP 4 Score: 53.1434 bits (126), Expect = 1.574e-7 Identity = 77/320 (24.06%), Postives = 127/320 (39.69%), Query Frame = 3
Query: 1014 WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTCIVRNCG--PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYR------LKGPKIAVC-LNGHWSPPQMPTCE 1940
W + + ++ C GY + G S+ +C EG W +C++ C PE F VA E +G+ A Y C +L+G C + G +P C P D A + + + T F + D V + C G+ ++ + C +G W+ P+C++ C P S ++ + S A + C GY I G + ++T D + G W++ P + C+ C P NG R T + +V+ Y C+ + ++ I VC NG W + PTCE
Sbjct: 35 WFFLQELVSYHCNIGYTVSGFSYSIRCV-EGGWTKHKFSCVLVTCKVLVEPENGFISVATEP-VYGSVASYMCADGYSLVGP-QLRRC----MQDGIWSDIDPVCEALSCPQPPDVANSAVVQMAQGT-FSLGDSVMYA------CRDGFSISGEAHITCLESGIWSKPPKCIDEDC-GNPGSPRHGRLEGSSFTEGDSATFVCDIGYKIG----GKDHINTTCD---SDGRWSR-PLQDCELLSCGSPQPILNG-----------RWTGNL---TYGQVITYSCNEGVKFSDGIMVESTSIVVCQANGLWL-GRPPTCE 316 HSP 5 Score: 47.7506 bits (112), Expect = 7.035e-6 Identity = 43/167 (25.75%), Postives = 65/167 (38.92%), Query Frame = 3
Query: 633 DDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC 1130
D+ G V C GY+ K +C + W C+ +C + ++GR + S A C+ GF + R C G+WSG C I C ++GEV+ +N + + C EG L G ++R CT G W G+ C
Sbjct: 406 DEVTVGTVVIFGCNKGYKLAGKP--TTECQPSLTWSSSIPSCQMVTC-RAAPLEHGRVNVTAVTPFGSAAAYDCDLGFVLV--------GQRVRVCLDTGEWSGSNPHCHRIKCKTPLELQHGEVVVDRENLNRV-IYVCHEGLVLEGPNVRMCTDAGTWSGTEPKC 560
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001629.1 (pep scaffold:Pmarinus_7.0:GL476369:34656:293612:-1 gene:ENSPMAG00000001441.1 transcript:ENSPMAT00000001629.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.9005 bits (237), Expect = 1.499e-20 Identity = 95/416 (22.84%), Postives = 158/416 (37.98%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SWNFI-PRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
C P PV+G + + V + + C GY L+G R+R C SG++P+C C P +P +S+ F + V C +GY+ S + NG W C +CG+ NG + +++T+ CN G++I + R C DG WSG +C I C + NG ++G + + ++ C GY+ C G W G C+ CG P K + A + C L+G +S C SG +P+C+ + ++ E N T + + V+ +C G+ + C + +W+ P C+ +C P + V L + + Y C G+Y+A
Sbjct: 2896 CGDPGIPVHGFRSADDVRVRSTIRFYCAEGYVLRGSRERVCNPGGVWSGTQPDC--HAVWC-GNPGVPAGGSILHSDGVVFSS--SVTYACWDGYQMSGLSTRLCSANGT-WTGVLPNCTVFNCGEPGTVANGVRI-GSDFTFGHNITYHCNPGYRID------PHHSSTRVCGKDGAWSGSLPLCRVITCRQPPRVVNGRLLGSDFSWGASVSYSCSSGYEPSFPATLTCEGNGTWRGDVPQCLPVFCGDPGTPAEGKREGKRFIFEADVSFSCNPPLVLVG-SSLRACRADRTWSG----TQPRCIDPSQTMCLNPGTPQFGEQNITQGYQVDSTVSF------RCQKGFHIQGSTTRTCLSDLTWSGTQPECISHSCKQLETPENADVGAVELPGLGYTLM--YSCQPGFYLA 3285 HSP 2 Score: 92.4337 bits (228), Expect = 1.774e-19 Identity = 104/427 (24.36%), Postives = 157/427 (36.77%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--TDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELN---SDILPACYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
C+ + + C P PV+G + D V +TC +GY +G CQAN + S S P C + TD P IP + S ++F G V C G+ + S ++ W + P +C SCG N + +T+ + CT + N R CQADG+W+G C C + P +G V S F C EGY L GS R C G W G+ C CG P + + + + Y C + G ++ L C +G LP +C F + ++F T G ++ CN GY ++ S +G+W+ +P C C +PP + + + Y C GY
Sbjct: 2708 CVPLPVCCGHPGNPVHGVTQGNWYSYSDVVNFTCNTGYTSEGSMHAQCQANGQWSSSIPVCKVVNCTD-----PGIPPNAIRKVSKGNENFMFGAMVFYECNPGFYL-FGSSVMTCQEKGTWDHHPSQCVVVSCGHPGVAPN-SLLSGEKFTFGATV--------TYSCTGSRLLIGNATRSCQADGRWTGSQPHCAGDYYGFCGDPGIPVHGFRSADDVRVRSTIRFYCAEGYVLRGSRERVCNPGGVWSGTQPDCHAVWCGNPGVPAGGSILHSDGVVFSSSVTYACWDGYQMSGLSTRL-CSANGTWTGVLP--------NCTVFNCGEPGTVANGVRIGSDF------TFGHNITYHCNPGYRIDPHHSSTRVCGKDGAWSGSLPLCRVITCR-QPPRVVNGRLLGSDFSWGASVSYSCSSGY 3103 HSP 3 Score: 91.6633 bits (226), Expect = 2.992e-19 Identity = 108/433 (24.94%), Postives = 166/433 (38.34%), Query Frame = 3
Query: 399 CQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQAN----LRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYD--PIKCEKKSCGKLE----DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVR-NCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSW-NFIPRCVEAACSARPPSMKYSTVRFLS-----LKHDSLARYYCHFGYYI 1631
C P P +G + + +G V + C +GY L G C + + S P C Q C +P + ++ + DF G V C GY A C N +W P +C C + D + R + N +++ I F QC F +CQA+G WS + C + C EL P N +G T + F+C+ G+ L GS +R+C G W G+ + CI +CGPP +V +V + Y+C LIG +S C + SG +P +C P V H N + ++ V CN GY + C NG W + IP C C+ P + + +R +S ++ Y C+ G+Y+
Sbjct: 2406 CSTPASPSHGLVLSQTGGQLGSGVRWACHTGYRLIGRSSAVCTQSPTGIFTWNTSVPAC--QAISC----GLPKSPIYGGIHAMDFSLGGHVAYSCNAGYTMVAGESASAVCLENGQWSNHNHPPQCTVVICPSVSAFSLDHGSWRVV-NGSHSEFGAQITF-------QCEPGYFLRGPSVIRCQANGTWSWNEERPTCEIMSCGELPIPANANKIGTQTTFGATAIFRCEMGFLLVGSVVRECLSSGLWSGNETRCIAAGHCGPPEALVNGEVVGVEFGYRDTVVYQCNPGFRLIG-SSVRVCQKDHKWSGQVP--------NCVPLPVCCG----HPGNPVHGVTQGNWYSYSDVVNFTCNTGYTSEGSMHAQCQANGQWSSSIPVCKVVNCTD--PGIPPNAIRKVSKGNENFMFGAMVFYECNPGFYL 2809 HSP 4 Score: 81.6481 bits (200), Expect = 4.052e-16 Identity = 101/397 (25.44%), Postives = 159/397 (40.05%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPR--KRYCQANLRLSGSE--PECTD---QTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE---NGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN--CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-NSDILPACYNGSWNFIP-RCVEAAC 1532
+ C P P+ G + +G V Y+C +GY + C N + S P+CT + FS + + V N + +F G + C+ GY S I + NG W + CE SCG+L P N + T+ + AI C GF + + R+C + G WSG+ C I PPE NGEV+GV ++C G++L GS +R C ++ W G C+ CG P V ++ + C + G TS + +G P C +++C P +A + + N+ NF+ G V +CN G+ L S ++ G+W+ P +CV +C
Sbjct: 2467 ISCGLPKSPIYGGIHAMDFSLGGHVAYSCNAGYTMVAGESASAVCLENGQWSNHNHPPQCTVVICPSVSAFSLDHGSWRVV--NGSHSEF--GAQITFQCEPGYFLRGPSVIRCQANGTWSWNEERPTCEIMSCGELPIPANANKI-GTQTTFGATAIFRCEMGFLLV--------GSVVRECLSSGLWSGNETRC--IAAGHCGPPEALVNGEVVGVEFGYRDTVVYQCNPGFRLIGSSVRVCQKDHKWSGQVPNCVPLPVCCGHPGNPVHGVTQGNWYSYSDVVNFTCNT-----GYTSEGSMHAQCQANGQWSSSIPVCKVVNCTDPGIPPNAIRKVSKGNE--NFMF------GAMVFYECNPGFYLFGSSVMTCQEKGTWDHHPSQCVVVSC 2835 HSP 5 Score: 77.7962 bits (190), Expect = 5.519e-15 Identity = 109/480 (22.71%), Postives = 163/480 (33.96%), Query Frame = 3
Query: 456 GDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKN--GEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKC-EKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKI----------------------------------------------------QCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG---EVMGVWNTVNSIKTF-KCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKM 1709
G Q+ + C+ GY L+GP CQAN S +E T + C P + N+N+ + G C+ G+ ++ +C + W + +C CG E NG + + Y+ + CN GF++ C T + + QCQA+G+WS +C + C + P N G N + F +C G+ L GS + C +G WD S C+V +CG P + ++ E T GA Y C LIG + +C G +P C F D + +H F D+V + +R C GY L C G W+ P C C S + + S Y C GY M LST + G WT +
Sbjct: 2555 GAQITFQCEPGYFLRGPSVIRCQANGTWSWNEERPTCEIMSCGELP------IPANANKIGTQTTFGATAIFRCEMGFL--LVGSVVRECLSSGLWSGNETRCIAAGHCGPPEALVNGEVV-GVEFGYRDTVVYQCNPGFRLIGSSVRVCQKDHKWSGQVPNCVPLPVCCGHPGNPVHGVTQGNWYSYSDVVNFTCNTGYTSEGSMHAQCQANGQWSSSIPVCKVVNCTDPGIPPNAIRKVSKGNENFMFGAMVFYECNPGFYLFGSSVMTCQEKGTWDHHPSQCVVVSCGHPGVAPNSLLSGEKFTFGATVTYSCTGSRLLIGNAT-RSC----QADGRWTGSQPHCAGDYYGFCGDPG-IPVH------GFRSADDVRVRSTIRFYCAEGYVLRGSRERVCNPGGVWSGTQPDCHAVWCGNPGVPAGGSILHSDGVVFSSSVTYACWDGYQ-------MSGLST--RLCSANGTWTGV 3004 HSP 6 Score: 67.0106 bits (162), Expect = 1.262e-11 Identity = 73/282 (25.89%), Postives = 99/282 (35.11%), Query Frame = 3
Query: 327 YDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKC---EKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTCIVRNCGPPP 1157
+ ++C D G + + + C+ P + VNG S G V Y+C SGY P C+ N G P+C C P T F DV C N S + A W +C + C P+ G Y S C GF IQ +T R C +D WSG C + C +L PEN +V V + + C+ G+ L G S R C +G W G C + GP P
Sbjct: 3049 HSSTRVCGKDGAWSGSLPLCRVITCRQPPRVVNGRLLGSDFSWGASVSYSCSSGYEPSFPATLTCEGNGTWRGDVPQCLPV--FCGD----PGTPAEGKREGKRFIFEADVSFSC-NPPLVLVGSSLRACRADRTWSGTQPRCIDPSQTMCLNPGTPQFGEQNITQGYQVDSTVSFRCQKGFHIQGSTT--------RTCLSDLTWSGTQPECISHSCKQLETPENADVGAVELPGLGYTLMYSCQPGFYLAGGSEHRSCRPDGTWSGKTPIC---HPGPKP 3312 HSP 7 Score: 56.225 bits (134), Expect = 2.473e-8 Identity = 115/543 (21.18%), Postives = 187/543 (34.44%), Query Frame = 3
Query: 432 ANHSILL------VGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADG-----------------KWSGDTAIC--------TAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREGN----WDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLI-GETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF---IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
AN IL+ +GD ++Y C G+ L G CQ RL + T Q LC + ++ + E +I GY Y + ++CG + + G T+ +QS Q+ D +I Q RR G +WS D A TA C + P +G V+ + S + C GY+L G CT+ W+ S C +CG P ++ + + G Y C + T++ GE++ C ++N P+C + P SA H + + N H E G + +C GY L + C NG+W++ P C +C P + + + A + C G+ + + ++ + G W+ T C P NGE+ ++ + V Y+C+P +RL G + VC H Q+P C
Sbjct: 2235 ANAEILMEDETFEIGDIIKYRCLLGFTLVGSEVLTCQLGTRLQANVASPTCQA-LC---------------STNEIRR-ESSGVILSPGYPSNYPN-------------------LQTCGWMLSVEKGYTITLYVEFFQS-EKQY--DELEIYDVVTQGPTSQGRRLAALSGDYSSPLNVTSASNQMFVRWSADHATSKKGFRISYTAQYCSTPASPSHGLVLSQTGGQLGSGVRWACHTGYRLIGRSSAVCTQSPTGIFTWNTSVPACQAISCGLPKSPIYGGIHAMDFSLGGHVAYSCNAGYTMVAGESASAVC--LENGQWSNHNHPPQCTVVICP--SVSAFSLDHGSWRVVNG-SHSEF--GAQITFQCEPGYFLRGPSVIRCQANGTWSWNEERPTCEIMSCGELPIPANANKIG-TQTTFGATAIFRCEMGFLL---------VGSVVRECLSSGLWSGNETRCIAAGHCGPPEALVNGEVV-------------GVEFGYRDTVVYQCNPGFRLIGSSVRVCQKDHKWSGQVPNC 2708
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010323.1 (pep scaffold:Pmarinus_7.0:GL476365:125003:472029:-1 gene:ENSPMAG00000009333.1 transcript:ENSPMAT00000010323.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.5153 bits (236), Expect = 2.078e-20 Identity = 129/526 (24.52%), Postives = 188/526 (35.74%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGP---RKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDN---SNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFG-YELNSDILPACYNGSWNF-IPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNK-GNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQ 1925
+ C PV P NG +G +V Y C GY GP C N S + P C + F+A ++ H + N D+K G + CQ GY I + NG W+ D +C SCG L NGR + + S AI C+ GF + + R+C A G WSG + C A C P NG V+G + ++C+ G++L GS +R C ++ W G C+ +CG P V + + C S G + + + W +P P C + P + N F+ G+ V C G Y + S +L NG W+ IP+C +C P+ S +F FG + G L C G WT + + +G+ R + VV++ C Y L GP VCL +G WS Q
Sbjct: 2475 ISCGIPVSPANGEILTVNYSIGGRVTYGCNRGYT-TGPGDTLAAVCLENGTWSNNNQPPMCNAIACMDFNA----FSLDHGSWLLLNGSDYKYGSRIIFHCQPGYTLLGPRIIQCQENGAWSWENDRPRCSLISCGSLSALPNGRKI-GTQTGFGSTAIYRCDPGFTLLGSQ--------VRECLASGLWSGTSNRCIAGHCGVPDPVTNGAVVGQSFGYHDTVVYRCQPGFRLVGSSVRMCQQDHQWSGQPPACVPISCGHPGTPVHGLTEGSSFHLYDTVNFTCNSGYISEGASQ----AQCMPDALW-SQPLPTCKVVSCPDPGEPLNGVRKVNKGYGKFVF------GSVVFYDCKQGFYLIGSSVLTCLPNGLWDRPIPQCFLVSCGHPGVAPNSLLSGEKFT-------------FGATVIYSCTGSRLLIGNATRSCQADGRWTGAQPHCSGDSAGSCGDPGIPSHGHRIGEEFRVK-----------SVVRFGCAVGYALHGPSERVCLPSGSWSRSQ 2951 HSP 2 Score: 88.5817 bits (218), Expect = 2.681e-18 Identity = 122/537 (22.72%), Postives = 179/537 (33.33%), Query Frame = 3
Query: 228 KPECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPI-KCEKKSCGKLEDPKNGRTMYNNNY---TYQSIAIQFCNDGFKI--------------------------------------------------QCTTDQFEDKNCRRQCQADGKWSGDTAICT---AILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSD--ILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
+P C + S ++ LPNG TA C + + + C+ G I C P NG D V Y C+ G+ L G R CQ + + SG P C + C P T VH + F + V C +GY S A+C + P+ C+ SC +P NG N Y + S+ C GF + CT + N R CQADG+W+G C+ A C + P +G +G V S+ F C GY LHG R C G+W S + C CG P + + + + Y C + G ++ L C +G LP C + V F + E T +V C GY ++S + +C +G+W+ +P C C +PP + + + Y C GY
Sbjct: 2596 RPRCSLISCGSLSALPNGRKIGTQTGFGSTAIYRCDPGFTLLGSQVRECLASGLWSGTSNRCIAGHCGVPDPVTNGAVVGQSFGYHDTVVYRCQPGFRLVGSSVRMCQQDHQWSGQPPACVPIS--CGH----PGTPVHGLTEGSSFHLYDTVNFTCNSGYISEGASQ--AQCMPDALWSQPLPTCKVVSCPDPGEPLNGVRKVNKGYGKFVFGSVVFYDCKQGFYLIGSSVLTCLPNGLWDRPIPQCFLVSCGHPGVAPNSLLSGEKFTFGATVIYSCTGSRLLIGNATRSCQADGRWTGAQPHCSGDSAGSCGDPGIPSHGHRIGEEFRVKSVVRFGCAVGYALHGPSERVCLPSGSWSRSQAECKAVWCGNPGVPAGGSILHSDGVVFSSSVTYACWDGYQMSGLSTRL-CSANATWTGVLPV--------CTVISCGNPGV------AANGFYLGKEFTFSQNVSYHCYPGYSMSSGATAVRSCQKDGTWSGALPSCHVITCR-QPPRVLNGRLLGSDFSWGASVSYSCSSGY 3108 HSP 3 Score: 85.8853 bits (211), Expect = 2.126e-17 Identity = 87/342 (25.44%), Postives = 129/342 (37.72%), Query Frame = 3
Query: 315 CWVEYDRA----QLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALK--GPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI-----LCPELSPPENGEVMGVWN-TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLP 1301
CW Y + +LC ++ G++ + + C P NG V Y C GY++ R CQ + SG+ P C T C P + ++ DF G V C +GYE + + + + NG W+ D +C CG P GR ++ Y+S C + + ++ R C ADG WSG C + CP + GE+ + V S F+C +GY + GS R C + W G+ CI +C A V A E G Y C+ L G + +C SG P
Sbjct: 2986 CWDGYQMSGLSTRLCSANATWTGVLPVCTVISCGNPGVAANGFYLGKEFTFSQNVSYHCYPGYSMSSGATAVRSCQKDGTWSGALPSCHVIT--CRQPPRV----LNGRLLGSDFSWGASVSYSCSSGYEPSFPATLTCEGNGT-WRGDVPQCLPIYCGDPGVPAEGRRE-GTSFMYKSKVAFSCKNTLLLVGSS--------LRMCTADGTWSGTQPRCIDLDPLQNTCPNPGALQFGELNSTFGFQVGSKVKFRCGKGYHILGSTTRSCQSDYVWSGTRPQCIPHSCRQLETPENADVGAVELPGLGYTLMYSCQPGFYLAGGSEHRSCRPDGTWSGKTP 3311 HSP 4 Score: 82.8037 bits (203), Expect = 1.711e-16 Identity = 102/432 (23.61%), Postives = 156/432 (36.11%), Query Frame = 3
Query: 399 CQPPVQPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYC----QANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYD--PIKCEKKSCGKLE----DPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWS--GDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVR-----FLSLKHDSLARYYCHFGYYI 1631
C P P +G + S + V + C GY L G C Q + P C Q C IP + + ++ G V C GY + A C N W + P C +C D + + ++Y Y S I C G+ + QCQ +G WS D C+ I C LS NG +G S ++C G+ L GS +R+C G W G+++ CI +CG P + V ++ + Y+C+ L+G +S C + SG P C P +H + ++F ++D V CN GY C + W+ +P C +C P + VR + S+ Y C G+Y+
Sbjct: 2414 CSIPAAPAHGSVMSQSGGHLNSVVWWACDRGYTLIGKSSAVCIKAPQGFHMWDSAVPTC--QAISC----GIPVSPANGEILTVNYSIGGRVTYGCNRGYTTGPGDTLAAVCLENGTWSNNNQPPMCNAIACMDFNAFSLDHGSWLLLNGSDYKYGSRIIFHCQPGYTLLGPR--------IIQCQENGAWSWENDRPRCSLISCGSLSALPNGRKIGTQTGFGSTAIYRCDPGFTLLGSQVRECLASGLWSGTSNRCIAGHCGVPDPVTNGAVVGQSFGYHDTVVYRCQPGFRLVG-SSVRMCQQDHQWSGQPPA--------CVPISCGHPGTPVHGLTEGSSFHLYDTVNF------TCNSGYISEGASQAQCMPDALWSQPLPTCKVVSCPD--PGEPLNGVRKVNKGYGKFVFGSVVFYDCKQGFYL 2814 HSP 5 Score: 80.1073 bits (196), Expect = 1.139e-15 Identity = 71/294 (24.15%), Postives = 112/294 (38.10%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLV-GDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI-----VRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETS 1256
C P P G HS +V V Y C GY + G R C AN +G P CT + C + P + +F ++V C GY + + C + W C +C + NGR + +++++ + C+ G++ C+ +G W GD C I C + P G G S F CK L GS LR CT +G W G+ CI C P + F ++ + G++ +++C ++G T+
Sbjct: 2959 CGNPGVPAGGSILHSDGVVFSSSVTYACWDGYQMSGLSTRLCSANATWTGVLPVCTVIS--CGN----PGVAANGFYLGKEFTFSQNVSYHCYPGYSMSSGATAVRSCQKDGTWSGALPSCHVITCRQPPRVLNGR-LLGSDFSWGASVSYSCSSGYE--------PSFPATLTCEGNGTWRGDVPQCLPIYCGDPGVPAEGRREGTSFMYKSKVAFSCKNTLLLVGSSLRMCTADGTWSGTQPRCIDLDPLQNTCPNPGALQFGELNSTFGFQVGSKVKFRCGKGYHILGSTT 3237 HSP 6 Score: 67.0106 bits (162), Expect = 1.130e-11 Identity = 54/207 (26.09%), Postives = 80/207 (38.65%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-----EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPE 992
+ + C P P G + + +V ++CK+ L G R C A+ SG++P C D L + P Q + ++ F+ G VK C GY HI+ + W +C SC +LE P+N + C GF + ++ R C+ DG WSG T IC P L P E
Sbjct: 3132 LPIYCGDPGVPAEGRREGTSFMYKSKVAFSCKNTLLLVGSSLRMCTADGTWSGTQPRCIDLDPLQNTCPNPGALQFGELNSTFGFQVGSKVKFRCGKGY------HILGSTTRSCQSDYVWSGTRPQCIPHSCRQLETPENADVGAVELPGLGYTLMYSCQPGFYLAGGSEH-------RSCRPDGTWSGKTPICH----PGLKPSE 3321 HSP 7 Score: 60.8474 bits (146), Expect = 9.086e-10 Identity = 63/253 (24.90%), Postives = 96/253 (37.94%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMY---NNNYTYQ-SIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLH-GSHLRKCTREGNWDGSNSTC 1130
+ C+ P + +NG S G V Y+C SGY P C+ N G P+C + P +P + ++ F V C+N S + +G W +C + P G + N+ + +Q ++F C G+ I +T R CQ+D WSG C C +L PEN +V V + + C+ G+ L GS R C +G W G C
Sbjct: 3076 ITCRQPPRVLNGRLLGSDFSWGASVSYSCSSGYEPSFPATLTCEGNGTWRGDVPQC---LPIYCGDPGVPAEGRREGTS---FMYKSKVAFSCKNTLLLVGSSLRMCTADGT-WSGTQPRCIDLDPLQNTCPNPGALQFGELNSTFGFQVGSKVKFRCGKGYHILGST--------TRSCQSDYVWSGTRPQCIPHSCRQLETPENADVGAVELPGLGYTLMYSCQPGFYLAGGSEHRSCRPDGTWSGKTPIC 3313 HSP 8 Score: 53.5286 bits (127), Expect = 1.979e-7 Identity = 106/446 (23.77%), Postives = 156/446 (34.98%), Query Frame = 3
Query: 669 CQNGYEDPYKSHII---AKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTA--ICTAILCPELSPPENGEVMGVWNTVN-------SIKTFKCKEGYQLHGSHLRKCTREGNWDGSNST--CIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLL-HCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSI-KPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
C GY KS + A + W C+ SCG P NG + NY+ CN G+ C +G WS + +C AI C + + G W +N S F C+ GY L G + +C G W N C + +CG + + T G+ A Y+C TL+G + C SG +C+ HC P V + V +F HD V + +C G+ L + C + W+ P CV +C P + + S + C+ GY +G + D W++ P C+ C P P NG R +K K + VV Y+C + L G + CL NG W P +P C +
Sbjct: 2441 CDRGYTLIGKSSAVCIKAPQGFHMWDSAVPTCQAISCGIPVSPANGEIL-TVNYSIGGRVTYGCNRGYTTG------PGDTLAAVCLENGTWSNNNQPPMCNAIACMDFNAFSLDH--GSWLLLNGSDYKYGSRIIFHCQPGYTLLGPRIIQCQENGAWSWENDRPRCSLISCGSLSALPNGRKIGTQTGFGSTAIYRCDPGFTLLG-SQVREC----LASGLWSGTSNRCIAGHCGVPDPVTNGAVV------GQSFGYHDTVVY------RCQPGFRLVGSSVRMCQQDHQWSGQPPACVPISC-GHPGTPVHGLTEGSSFHLYDTVNFTCNSGYI----SEGASQAQCMPDAL-----WSQ-PLPTCKVVSCPDPGEPLNG----------VRKVNKGYGKFVFGSVVFYDCKQGFYLIGSSVLTCLPNGLWDRP-IPQCFLV 2838
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003453.1 (pep scaffold:Pmarinus_7.0:GL476692:191866:231388:-1 gene:ENSPMAG00000003157.1 transcript:ENSPMAT00000003453.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.2041 bits (230), Expect = 6.458e-20 Identity = 86/336 (25.60%), Postives = 126/336 (37.50%), Query Frame = 3
Query: 333 RAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALK--GPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC---TAILCPELSPPENG-EVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC 1319
R + C + G + I + C P P N G V Y C GY ++ +R C SG+ P C + C P + +H DF G V C GY+ + + + + G EW + +C CG P NG ++T+QS C + + +R C A G WSG C + C P NG + + V S +F+CK+G+ + GS R C + W+G C+ C P +A V A + G Y C+ L G + TC D + W KP P C
Sbjct: 339 RTRHCSANGTWSGSLPSCIVITCGDPGTPANAVRTGVDFTFGHNVTYRCHPGYTMEPTTQSQRVCTKEGVWSGNLPLC--KIIRCQEPPVV----MHGRRESGDFTWGSAVAYGCLAGYQLSHSATLFCEGRG-EWTGELPQCLPMFCGDPGVPANGERQ-GRSFTFQSEV--------SFTCASPLVLVGSAKRVCMASGMWSGTQPRCIEASHTTCTNPGTPHNGFQNFSLGYQVGSTVSFECKKGFHIQGSSTRTCLPDLTWNGLQPECVSHRCSQPETPAYADVRAQDVAQLGYTLLYSCQPGYYLSGGSEHRTC---DPEGAWSGKP-PLC 654 HSP 2 Score: 84.3445 bits (207), Expect = 3.636e-17 Identity = 73/310 (23.55%), Postives = 122/310 (39.35%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA---ILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP-PEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPK 1304
+ + C P PV+G A+ + D V ++C G+ + GP C + + S P C + C ++ + + + F G V C+ GY S + + +G +W P C +C P +G + +TY S C++ + + R CQA G WSG T +C+ C + P +G G S+ +F C +GY L GS R C G+W G+ C C P + ++ ++ Y C+ ++G+ + C SG LP
Sbjct: 59 VPISCGHPGSPVHGIAHGGRFNLDDVVGFSCDVGFVIHGPESTQCLPSGQWSDPLPVC--KVVNCTGPAHVENSYLEIKNKNKMFTYGTLVSYHCKPGYYLMGSSTLSCQPSG-QWDKPPPVCTVVNCSHPGLPPHG-ILAAEGFTYGSSVTYSCSERRALL--------GHPTRTCQASGHWSGSTPLCSGDGHGACGDPGVPPHGSRRGGAFRTESVVSFSCDDGYVLRGSERRSCLANGSWSGTQPDCREFQCALPFSDRDGSRPSWAGAVFPDSVTYACRDGFRMLGQRT-RHCSANGTWSGSLPS 355 HSP 3 Score: 82.8037 bits (203), Expect = 1.292e-16 Identity = 69/251 (27.49%), Postives = 101/251 (40.24%), Query Frame = 3
Query: 390 DLQCQPPVQPVNG-HANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI 1133
+ QC P +G + + + D V Y C+ G+ + G R R+C AN SGS P C T P P V DF G +V C GY E +S + G W + C+ C + +GR + ++T+ S C G+++ + F C+ G+W+G+ C + C + P NGE G T S +F C L GS R C G W G+ CI
Sbjct: 299 EFQCALPFSDRDGSRPSWAGAVFPDSVTYACRDGFRMLGQRTRHCSANGTWSGSLPSCIVIT---CGDPGTPANAVRTGV---DFTFGHNVTYRCHPGYTMEPTTQSQRVCTKEG-VWSGNLPLCKIIRCQEPPVVMHGRRE-SGDFTWGSAVAYGCLAGYQLSHSATLF--------CEGRGEWTGELPQCLPMFCGDPGVPANGERQGRSFTFQSEVSFTCASPLVLVGSAKRVCMASGMWSGTQPRCI 533 HSP 4 Score: 82.0333 bits (201), Expect = 2.022e-16 Identity = 93/372 (25.00%), Postives = 137/372 (36.83%), Query Frame = 3
Query: 444 ILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKK---SCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTV--NSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGET-SFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYN-GSWNF-IPRCVEAAC 1532
+ G V Y CK GY L G CQ + + P CT + S P +P H + F G V C H C + W C +CG P +G + + +S+ C+DG+ ++ + RR C A+G WSG C C +G V +S+ T+ C++G+++ G R C+ G W GS +CIV CG P A T G Y+C T+ T S C + SG LP CK + V +H ++ +F V +G C GY+L+ C G W +P+C+ C
Sbjct: 140 MFTYGTLVSYHCKPGYYLMGSSTLSCQPSGQWDKPPPVCTV---VNCSHPGLP---PHGILAAEGFTYGSSVTYSCSE--RRALLGHPTRTCQASGHWSGSTPLCSGDGHGACGDPGVPPHG-SRRGGAFRTESVVSFSCDDGYVLRGSE--------RRSCLANGSWSGTQPDCREFQCALPFSDRDGSRPSWAGAVFPDSV-TYACRDGFRMLGQRTRHCSANGTWSGSLPSCIVITCGDPGTPANAVRTGVDFTFGHNVTYRCHPGYTMEPTTQSQRVCTKEGVWSGNLPL--------CKIIRCQEPPVVMHGRRESGDFTWGSAVAYG------CLAGYQLSHSATLFCEGRGEWTGELPQCLPMFC 479 HSP 5 Score: 75.0998 bits (183), Expect = 2.642e-14 Identity = 98/404 (24.26%), Postives = 154/404 (38.12%), Query Frame = 3
Query: 768 CGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEI----VFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCV---EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFI 1946
CG LE NG+ + +Y Y+ + C+ GF++ + R CQ D WSG++ C I C P +G G ++ + F C G+ +HG +C G W C V NC P + + K + T+G Y CK L+G +S L+C SG KP P C +++C H + + T+G+ V C+ L C +G W+ P C AC P + + R + + +S+ + C GY + G E S + + G+W+ + C+ +C L SDR + V Y C +R+ G + C NG WS +P+C I
Sbjct: 5 CGVLEPIVNGQVV-GESYGYRDTVVYQCSPGFRLIGFS--------VRICQQDHNWSGNSPACVPISCGHPGSPVHGIAHGGRFNLDDVVGFSCDVGFVIHGPESTQCLPSGQWSDPLPVCKVVNCTGPAHVENSYLEIKNKNKMFTYGTLVSYHCKPGYYLMG-SSTLSC----QPSGQWDKPPPVCTVVNCS-----------HPGLPPHGILAAEGFTYGSSVTYSCSERRALLGHPTRTCQASGHWSGSTPLCSGDGHGAC-GDPGVPPHGSRRGGAFRTESVVSFSCDDGYVL----RGSERRSCLAN-----GSWSGTQPD-CREFQCA------------LPFSDRDGSRPSWAGAVFPDSVTYACRDGFRMLGQRTRHCSANGTWS-GSLPSCIVI 359 HSP 6 Score: 62.7734 bits (151), Expect = 2.245e-10 Identity = 96/420 (22.86%), Postives = 148/420 (35.24%), Query Frame = 3
Query: 420 VNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--EDPYKSHIIAKCNGNEWKYDPIK-CEKKSCGKLEDPKNGRTMYNNN---YTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNF---IMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
VNG D V Y C G+ L G R CQ + SG+ P C + C P + VH ++ F + V C G+ P + + +W DP+ C+ +C +N N +TY ++ C G+ + ++ CQ G+W +CT + C P +G + T S T+ C E L G R C G+W GS C CG P A + + C L G +C + SG P C+ FQ A + + ++ + D VT+ C G+ + C NG+W+ +P C+ C P + + V F + H+ Y CH GY +
Sbjct: 12 VNGQVVGESYGYRDTVVYQCSPGFRLIGFSVRICQQDHNWSGNSPACVPIS--CGH----PGSPVHGIAHGGRFNLDDVVGFSCDVGFVIHGPESTQCLPS---GQWS-DPLPVCKVVNCTGPAHVENSYLEIKNKNKMFTYGTLVSYHCKPGYYLMGSST--------LSCQPSGQWDKPPPVCTVVNCSHPGLPPHGILAAEGFTYGSSVTYSCSERRALLGHPTRTCQASGHWSGSTPLCSGDGHGACGDPGVPPHGSRRGGAFRTESVVSFSCDDGYVLRGSER-RSCLANGSWSGTQPD--------CREFQC--ALPFSDRDGSRPSWAGAVFPDSVTY------ACRDGFRMLGQRTRHCSANGTWSGSLPSCIVITCGDPGTPANAVRTGVDF-TFGHN--VTYRCHPGYTM 393 HSP 7 Score: 53.9138 bits (128), Expect = 1.041e-7 Identity = 43/199 (21.61%), Postives = 70/199 (35.18%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-----EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAIL 968
+ + C P P NG +V +TC S L G KR C A+ SG++P C + + + P P+ + S ++ G V C+ G+ HI W +C C + E P + + C G+ + ++ R C +G WSG +C A +
Sbjct: 475 LPMFCGDPGVPANGERQGRSFTFQSEVSFTCASPLVLVGSAKRVCMASGMWSGTQPRCIEASHTTCTNPGTPHNGFQNFSL--GYQVGSTVSFECKKGF------HIQGSSTRTCLPDLTWNGLQPECVSHRCSQPETPAYADVRAQDVAQLGYTLLYSCQPGYYLSGGSEH-------RTCDPEGAWSGKPPLCHATV 658
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009096.1 (pep scaffold:Pmarinus_7.0:GL479728:66801:80742:-1 gene:ENSPMAG00000008231.1 transcript:ENSPMAT00000009096.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 65.855 bits (159), Expect = 1.157e-11 Identity = 99/391 (25.32%), Postives = 138/391 (35.29%), Query Frame = 3
Query: 399 CQPPVQPVNGH--ANHSILLVGDQVEYTCKSGYAL--KGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWK-YDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPP---ENGEVMGVWNTV---NSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCI---VRNCGPPPEIVFAKVAYEATTH--GAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCV 1520
C PP + NG + ++ V D V Y C SGYA + C AN C +T C P + S G+ + C GY K++ + W DP C+ SC +++ + + Y Y S C GF + D F D C GKWSG IC +P +G+ MG N I ++C Y+ S + CT W + C+ V C PP I V + + G A YKC+ L G + + C E D W P + P V + K I E KT +G V C+ Y L + C NG W+ P C
Sbjct: 22 CGPPPRVNNGRPDSTNTFFPVNDMVRYQCNSGYAATKNSSLRLQCVANGTWGELNYWCERKT--CSPKP------IDQGSYTGGISFGDTITYTCDTGYALTGKTYQLTCMADGTWNPVDPPDCQSVSCPEIDLTEKLVFQLSLQYQYGSRVTYSCEAGFSL--IGDSFRD------CLESGKWSGSNPICKVSDVKCKTPQWDISHGQAMGERKEAYKYNDIVRYECSARYRAEPSEIH-CTESNEWSAT-VNCVFKAVTVCRSPPLIGNGDVVQPKSEYAMGDSASYKCRKGYRLEGNETAV-CRENDQ---WTQPPTCASVTCGPPATVINGK--IKEQAKT-------PYAYGDRVSYICDDTYHLVGNGEITCQNNGQWSPSPSCA 381 HSP 2 Score: 65.0846 bits (157), Expect = 1.607e-11 Identity = 91/371 (24.53%), Postives = 134/371 (36.12%), Query Frame = 3
Query: 639 FKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKN-GRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSG-DTAICTAILCPELSPPENGEV-MGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN--CGPPPEIVFAKVAY----EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKC-NKGNWTKMPT 1715
F + V+ C +GY S + +C N W CE+K+C PK + Y ++ C+ G+ + T Q C ADG W+ D C ++ CPE+ E + + S T+ C+ G+ L G R C G W GSN C V + C P + A EA + Y+C +R E S + C E + S + C+ K V + I + E G KC GY L + C N W P C C PP +TV +K + Y +G ++ D L +I C N G W+ P+
Sbjct: 40 FPVNDMVRYQCNSGYAATKNSSLRLQCVANGTWGELNYWCERKTC----SPKPIDQGSYTGGISFGDTITYTCDTGYALTGKTYQL-------TCMADGTWNPVDPPDCQSVSCPEIDLTEKLVFQLSLQYQYGSRVTYSCEAGFSLIGDSFRDCLESGKWSGSNPICKVSDVKCKTPQWDISHGQAMGERKEAYKYNDIVRYECSAR--YRAEPSEIHCTESNEWSATV-----NCVF--KAVTVCRSPPLIGNGDVVQ---PKSEYAMGDSASYKCRKGYRLEGNETAVCRENDQWTQPPTCASVTCG--PP----ATVINGKIKEQAKTPY--AYGDRVSYICDDTYHLVGNGEITCQNNGQWSPSPS 379
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Match: EDO36503 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF8]) HSP 1 Score: 129.413 bits (324), Expect = 6.149e-31 Identity = 88/286 (30.77%), Postives = 125/286 (43.71%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGED-VKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE 1250
C P V P+NG S+ + + + C G+ L G KR CQ+N R SG Q C + P T + S + V C G++ + C N W D + C+ + CG L P NG T + T+ + C++GF + + + R CQ++GKWSG C A C L P NG +G T + TF C EG+ L GS +R C + W GS TC VR+CGP P K+ TT+ + ++C LIG
Sbjct: 658 CGPLVSPLNGTKTGSLTTFPNIITFKCDPGFNLIGSPKRTCQSNARWSG-------QMVSCKARDCGPLTTPRNGSKLGSLTTFPNKVHFWCDEGFD--LLGSKLRVCQANAIWSGDKVTCQARDCGPLNTPLNG-TKTGSLTTFPNTVKFMCDEGFNLIGSRN--------RTCQSNGKWSGQQVACGARDCGPLPTPMNGTKIGSLTTFPNKVTFTCVEGFNLIGSSIRHCQSDSTWSGSQPTCKVRDCGPLPVPANGKMLGLHTTYPSDIHFRCYKGFNLIGS 925 HSP 2 Score: 109.383 bits (272), Expect = 1.127e-24 Identity = 87/338 (25.74%), Postives = 143/338 (42.31%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQT------------------DLCFSAPYIPYTQVHDNSNRDDFK-----------NGEDV----------KIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMG-VWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSG 1292
C P P NG VG +V +TCK G+ LKG R C + + +G++P C +T L S + ++ SN NG + + C G+E + +A C + + C +CG L+ P +G ++ ++ T+ S + C+ G+ + + R C + WSG C A+ C +L+ P NG +G +W N+++ F C EG++L GS +R C +G+W+G+ S C +CGP P + + EAT + Q E KC R ++ + F C + SG
Sbjct: 213 CGDPGLPENGAKVGLSYGVGARVFFTCKLGFNLKGSPSRRCGEDNKWTGTQPRCESKTVSFAERALAEEAFRLFYYKLPLSTLQKSHVDINSGSNSGSLALETLALIEAPTNGSVIGNETTFQKIMRFACDPGFE--MDGNPVAICQSDGKWSSTVTCNPVNCGSLDAPAHG-SVSGDSTTFTSRLVFSCDAGYIMSGSP--------IRTCLKNASWSGTQPRCDAVECGKLAVPRNGTRVGTLWTFPNTVR-FACDEGFELSGSAVRTCQADGSWNGTLSECNAVDCGPLPVPMNGSIPGEATVYPFQREVKCD-RGFILRGSRFRLCQADGSWSG 537 HSP 3 Score: 105.916 bits (263), Expect = 1.528e-23 Identity = 102/413 (24.70%), Postives = 156/413 (37.77%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIP-RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY 1625
L C P+NG + +QV ++C G+ L G +R C +N SG C P + + F N + C G+ + N W + C+ + CG L P+NG + + T+ + +C++GF D K R CQA+ WSGD C A C L+ P NG G T + F C EG+ L GS R C G W G C R+CGP P + TT + + C LIG +S C SG +P C + D + + N K ++ T+ + + +C G+ L +C N W+ C C M S+V L++ ++ ++ C G+
Sbjct: 598 LDCGFLATPMNGSKIGAKTFFPNQVLFSCDEGFELIGSARRACLSNGSWSGVSVICKAHD----CGPLVSPLNGTKTGSLTTFPN--IITFKCDPGFNLIGSPKRTCQSNA-RWSGQMVSCKARDCGPLTTPRNGSKL-GSLTTFPNKVHFWCDEGF------DLLGSK--LRVCQANAIWSGDKVTCQARDCGPLNTPLNGTKTGSLTTFPNTVKFMCDEGFNLIGSRNRTCQSNGKWSGQQVACGARDCGPLPTPMNGTKIGSLTTFPNKVTFTCVEGFNLIG-SSIRHCQSDSTWSG----SQPTCKVR------DCGPLPVPANGK----MLGLHTTYPSDIHFRCYKGFNLIGSPTRSCQSNAKWSGKEVSCNAVDCGPLAAPMNGSSVGNLTV-FPNIIKFICDEGF 978 HSP 4 Score: 97.8265 bits (242), Expect = 5.777e-21 Identity = 72/250 (28.80%), Postives = 107/250 (42.80%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNG--EDVKIICQNGYE---DPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC 1130
C P P+NG S+ ++V +TC G+ L G R+CQ++ SGS+P C + C P V N D+ C G+ P +S C N +W + C CG L P NG ++ N + +I C++GF + ++ +C +DGKW G T C A+ C L P NG +MG + +F C +G+ L GS +R C W G N+ C
Sbjct: 832 CGPLPTPMNGTKIGSLTTFPNKVTFTCVEGFNLIGSSIRHCQSDSTWSGSQPTC--KVRDCGPLP------VPANGKMLGLHTTYPSDIHFRCYKGFNLIGSPTRS-----CQSNAKWSGKEVSCNAVDCGPLAAPMNGSSV-GNLTVFPNIIKFICDEGFDLLGSSVW--------RCSSDGKWDGITTTCKAVDCGPLVKPLNGSMMGSLTYYPNHVSFTCDKGFLLRGSEVRACQANRTWSGMNTRC 1059 HSP 5 Score: 96.2857 bits (238), Expect = 1.793e-20 Identity = 103/444 (23.20%), Postives = 161/444 (36.26%), Query Frame = 3
Query: 372 LVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA--------ILCPE-------------------------------------LSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWN-FIPRCVEAACSARPPSMKYS 1562
+ C+ + L C P N + D V YTC G+ + G + C A G+ P C C +IP N ++ + +GE V C+ GY + + C +W P KCEK CG P+NG + +Y + C GF ++ + R+C D KW+G C + L E + P NG V+G T I F C G+++ G+ + C +G W S TC NCG V+ ++TT ++ + C + + G + TC + + SG +P+C V+ K+ + N + T VR C+ G+EL+ + C +GSWN + C C P M S
Sbjct: 87 VTCLLVGLSCGQPRDVRNAEYKLTGTGFNDNVTYTCNEGFTVIGTVTKRCTAKGEWGGALPTCMAD---CPKPSHIPENAFIVN-EKERYMSGERVTFKCKPGYNQEGLATTL--CFLGDWNIMPFKCEKGGCGDPGLPENGAKV-GLSYGVGARVFFTCKLGFNLKGSPS--------RRCGEDNKWTGTQPRCESKTVSFAERALAEEAFRLFYYKLPLSTLQKSHVDINSGSNSGSLALETLALIEAPTNGSVIGNETTFQKIMRFACDPGFEMDGNPVAICQSDGKWS-STVTCNPVNCGSLDAPAHGSVSGDSTTFTSRLVFSCDAGYIMSG-SPIRTCLKNASWSG----TQPRCD------AVECGKLAVPRNGTRVGTLW----TFPNTVRFACDEGFELSGSAVRTCQADGSWNGTLSECNAVDCGPLPVPMNGS 499 HSP 6 Score: 92.0485 bits (227), Expect = 3.403e-19 Identity = 74/286 (25.87%), Postives = 116/286 (40.56%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE 1250
++C P NG ++ + V + C G+ L G R CQA+ +G+ EC + D C P + + F+ ++ C G+ + + +G+ W + CG L P NG T + T+ + C++GF + + R CQ+ GKWSG+ C A+ C L+ P NG +G + F C EG++L GS R C G+W G + C +CGP + TT +KC LIG
Sbjct: 429 VECGKLAVPRNGTRVGTLWTFPNTVRFACDEGFELSGSAVRTCQADGSWNGTLSEC-NAVD-CGPLPVPMNGSIPGEATVYPFQR----EVKCDRGFILRGSRFRLCQADGS-WSG-----RTRDCGPLATPTNG-TKTGSLTTFPNKVTFSCDEGFILIGSP--------LRSCQSSGKWSGEQVRCEALDCGFLATPMNGSKIGAKTFFPNQVLFSCDEGFELIGSARRACLSNGSWSGVSVICKAHDCGPLVSPLNGTKTGSLTTFPNIITFKCDPGFNLIGS 693 HSP 7 Score: 85.1149 bits (209), Expect = 5.162e-17 Identity = 78/290 (26.90%), Postives = 108/290 (37.24%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDD----FKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE 1250
+ C P +G + ++ ++C +GY + G R C N SG++P C A V N R F N V+ C G+E + + +G+ W +C CG L P NG ++ Y C+ GF ++ +F R CQADG WSG T C L+ P NG G T + TF C EG+ L GS LR C G W G C +CG + T Q + C LIG
Sbjct: 371 VNCGSLDAPAHGSVSGDSTTFTSRLVFSCDAGYIMSGSPIRTCLKNASWSGTQPRC--------DAVECGKLAVPRNGTRVGTLWTFPN--TVRFACDEGFELSGSAVRTCQADGS-WNGTLSECNAVDCGPLPVPMNG-SIPGEATVYPFQREVKCDRGFILR--GSRF------RLCQADGSWSGRTRDCG-----PLATPTNGTKTGSLTTFPNKVTFSCDEGFILIGSPLRSCQSSGKWSGEQVRCEALDCGFLATPMNGSKIGAKTFFPNQVLFSCDEGFELIGS 635 HSP 8 Score: 83.9593 bits (206), Expect = 1.001e-16 Identity = 84/364 (23.08%), Postives = 137/364 (37.64%), Query Frame = 3
Query: 909 RQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVR-NCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIP-RCVEAACSARPPSMKYSTVRFLSLKHDSLARYY--CHFGYYIA---LRKDGMETLSTIFDIKCNKGN----------------WTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSI---KPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWS 1916
R+C D KW+G C + C L P NG V+G T + I F C GY++HG C G W + + +V +CG P ++ A+ T Y C T+IG T C G L P C+ C KP + ++E + G V KC GY C+ G WN +P +C + C P + + + + L + AR + C G+ + R+ G + T +C + K+P Q +G + L + T+ S+ + +++++ C P + + G +A+C +G WS
Sbjct: 17 RKCGKDNKWTGTQPRCEIVDCGPLRAPMNGHVIGNETTFHKIVRFSCNPGYKMHGYPDAICQANGEWSNTVTCLLVGLSCGQPRDVRNAEYKLTGTGFNDNVTYTCNEGFTVIG-TVTKRCTAKGEWGGAL----PTCMADCPKPSHIPENAFIVNE---------KERYMSGERVTFKCKPGYNQEGLATTLCFLGDWNIMPFKCEKGGCGD--PGLPENGAK-VGLSYGVGARVFFTCKLGFNLKGSPSRRCGEDNKWTGTQPRCESKTVSFAERALAEEAFRLFYYKLPLSTLQKSHVDINSGSNSGSLALETLALIEAPTNGSVIGNETTFQKIMRFACDPGFEMDGNPVAICQSDGKWS 363 HSP 9 Score: 73.559 bits (179), Expect = 1.711e-13 Identity = 109/434 (25.12%), Postives = 169/434 (38.94%), Query Frame = 3
Query: 465 VEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKC--EKKSCGKLEDPKNGR-----TMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELS-PPENGEVMGVWNTVNSIK--TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP--PEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSA--------------KVYIHENNK-----------------TTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
V + CK G+ L G R C + + +G++P C ++ P H N F + V+ C GY+ I + NG EW + + C SCG+ D +N T +N+N TY CN+GF + T ++C A G+W G C A CP+ S PEN ++ S + TFKCK GY G C G+W+ C CG P PE AKV GA+ + CK L G S CGE + +G P+ E K + + + A K ++ N+ T ++ +E T +R C+ G+E++ + + C +G W+ C C + + + +V S S + C GY ++
Sbjct: 1 VFFMCKYGFKLIGSPVRKCGKDNKWTGTQPRC----EIVDCGPLRAPMNGHVIGNETTFH--KIVRFSCNPGYKMHGYPDAICQANG-EWS-NTVTCLLVGLSCGQPRDVRNAEYKLTGTGFNDNVTYT------CNEGFTVIGTVT--------KRCTAKGEWGGALPTCMAD-CPKPSHIPENAFIVNEKERYMSGERVTFKCKPGYNQEGLATTLCFL-GDWNIMPFKCEKGGCGDPGLPENG-AKVGLSYGV-GARVFFTCKLGFNLKGSPS-RRCGEDNKWTGTQPRCESKTVSFAERALAEEAFRLFYYKLPLSTLQKSHVDINSGSNSGSLALETLALIEAPTNGSVIGNETTFQKIMRFACDPGFEMDGNPVAICQSDGKWSSTVTCNPVNCGSL-DAPAHGSVSGDSTTFTSRLVFSCDAGYIMS 406
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Match: EDO36504 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF9]) HSP 1 Score: 120.168 bits (300), Expect = 3.429e-28 Identity = 84/296 (28.38%), Postives = 129/296 (43.58%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDV-KIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETS 1256
C +D C P PVNG + S+ +++ + C G+ L G R R CQ N + SG +T C + P + + S +V K C G+ D S + + +W + C+ CG L P NG ++ N T I+F C++GF + ++ RQC + GKW+G C A+ C L P NG +G + TF C EG+ + GS R+C W G+ +TC +CGP V +A +ATT + C L+G ++
Sbjct: 157 TCKAVD--CGPLTVPVNGSSAGSLTYFPNKISFECDKGFLLDGSRVRVCQENRKWSG-------ETTTCNAVDCGPLSIPLNGSRTGSLTIFPNVVKFSCDEGF-DLLGSSVRQCTSKGQWDGNTASCKAVDCGPLAAPMNGSSV--GNLTVFPNIIKFSCDEGFDLLGSS--------VRQCTSTGKWAGSKTSCKAVDCGPLPVPLNGTRVGSLTFYPNTMTFACDEGFLIRGSVTRRCQLNRRWSGTRTTCNAVDCGPLATPVNGSLAGDATTFPNIIRFTCDEGFDLLGSSA 432 HSP 2 Score: 108.227 bits (269), Expect = 1.754e-24 Identity = 75/263 (28.52%), Postives = 114/263 (43.35%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPP 1157
+C +D C P P+NG + + + + ++C G+ L G R C A R SG++ C D P + F N + C G+ + C N +W + C CG L P NG + T ++F C++GF + ++ RQC + G+W G+TA C A+ C L+ P NG +G +I F C EG+ L GS +R+CT G W GS ++C +CGP P
Sbjct: 99 ICRAVD--CGPLSPPMNGTLSGHLTVFPNSFSFSCDEGFDLLGSSVRQCTAERRWSGTQTTC-KAVDC---GPLTVPVNGSSAGSLTYFPN--KISFECDKGFL--LDGSRVRVCQENRKWSGETTTCNAVDCGPLSIPLNGS--RTGSLTIFPNVVKFSCDEGFDLLGSS--------VRQCTSKGQWDGNTASCKAVDCGPLAAPMNGSSVGNLTVFPNIIKFSCDEGFDLLGSSVRQCTSTGKWAGSKTSCKAVDCGPLP 341 HSP 3 Score: 106.301 bits (264), Expect = 7.316e-24 Identity = 91/348 (26.15%), Postives = 132/348 (37.93%), Query Frame = 3
Query: 210 MKSAQYKPECHVKSLDNVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGET 1253
M S Y P HV + L G +AC AN W + C +D C P P NG + S+ + + +TC G+ L G R C + G+ C S P H + F C G+ D S + W C+ CG L P NG + + Y I+ + C+ GF + D + R CQ + KWSG+T C A+ C LS P NG G ++ F C EG+ L GS +R+CT +G WDG+ ++C +CGP + T ++ C L+G +
Sbjct: 1 MGSLTYYPN-HVSFTCDKGFLLRGSEVRACQAN-RTWSGMNTR-------------CEAVD--CGPLAAPRNGSMSGSLTVYPNTKTFTCDRGFELLGSSLRRCTPSGLWDGTNAICRAVDCGPLSPPMNGTLSGHLTVFPNSF------SFSCDEGF-DLLGSSVRQCTAERRWSGTQTTCKAVDCGPLTVPVNGSSAGSLTYFPNKISFE-CDKGFLL--------DGSRVRVCQENRKWSGETTTCNAVDCGPLSIPLNGSRTGSLTIFPNVVKFSCDEGFDLLGSSVRQCTSKGQWDGNTASCKAVDCGPLAAPMNGSSVGNLTVFPNIIKFSCDEGFDLLGSS 315 HSP 4 Score: 99.3673 bits (246), Expect = 1.124e-21 Identity = 79/304 (25.99%), Postives = 128/304 (42.11%), Query Frame = 3
Query: 375 VCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--------TDQTDLCFSAPY----IPYTQVHDNSNRDDFKNGED---------VKIICQN------GYEDP-YKSHIIAKCNGNEWKYDPIKCEK------------KSCGKLEDPKNG-----RTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGP 1151
C +D C P PVNG + + +TC G+ L G R C + + +G+ C DL S+ + I + +H + + G+ + ++ + G P ++ + EW + ++ K CG L P+NG RT + N T++ C+ GF ++ ++ R CQA+ WSG+T C A+ C L+ P NG ++G S+ +F C EG+ L GS LRKCT EG WDGS+++ + +CGP
Sbjct: 389 TCNAVD--CGPLATPVNGSLAGDATTFPNIIRFTCDEGFDLLGSSARKCMPSRKWNGTLTSCKGKHVIHLMSSEDLGASSVHHQYVIDTSSLHHLNGNGRYPEGDKKGNLSKKCFIMLLLSDESRLRRGVRPPRFECENMHLKRSMEWDENYVQSNKILKNNIQVPLVAVDCGPLPSPRNGSMEGSRTFFPNKITFR------CDKGFTLKGSST--------RVCQANRAWSGETTTCQAVDCGRLNAPVNGSMIGALTVYPSVISFSCDEGFDLLGSSLRKCTSEGRWDGSSTSSV--DCGP 674 HSP 5 Score: 70.8626 bits (172), Expect = 1.031e-12 Identity = 41/158 (25.95%), Postives = 73/158 (46.20%), Query Frame = 3
Query: 657 VKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC 1130
+ C G+ S + + N W + C+ CG+L P NG +M Y S+ C++GF + ++ R+C ++G+W G + +++ C LS P NG +G + FKC +G+ + GS +R C W+G+ ++C
Sbjct: 580 ITFRCDKGFTLKGSSTRVCQAN-RAWSGETTTCQAVDCGRLNAPVNG-SMIGALTVYPSVISFSCDEGFDLLGSS--------LRKCTSEGRWDGSST--SSVDCGPLSAPTNGSKIGSLTYYPNKVWFKCNKGFLMRGSQVRACQANQRWNGTRTSC 725
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Match: EDO43337 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ29]) HSP 1 Score: 103.99 bits (258), Expect = 3.814e-24 Identity = 95/367 (25.89%), Postives = 130/367 (35.42%), Query Frame = 3
Query: 471 YTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGP-PPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKV------------YIHENNKT----TNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWN-FIPRC 1517
Y+C Y +GP R C+ + G + C C IPY + + G ++ C G + S +I +W C KSCG P NGR YT++S C+ G RQCQ++ KWSG T C C + P NG G T S F C G+ G R+C W G TC +CG P AK TT+ + ++C + + + C E G K C P + D YI+ + T NF M HG V CN G++L C +G+WN IP C
Sbjct: 2 YSCTQPYQRRGPETRTCRGIGKWDGKKTRCRK---FCKDPGDIPYGNRDKGRSDSSHRVGTSIRYWCFPGTQ-LVGSAVITCMKSGDWSDKTPNCSPKSCGDPGTPANGR-RSGQVYTFKSKVFFSCDRG--------HIRVGPAFRQCQSNQKWSGVTPTCQPKSCGDPGTPANGGRSGQVYTFKSKVFFSCDRGHIRVGPAFRQCQSNQKWSGVTPTCQPVDCGSLPTPKNGAKTEETKTTYQGRVSFRCVKKGHELKGSRVRVCQEDGRWDGTFTK--------CDPVECDDPGTPRFGGRNPDKDKYIYGDTVTYECKKNFTMRSNYEHGQSVSFGCNKGFQLKGASAIVCNSGNWNDTIPTC 347 HSP 2 Score: 71.633 bits (174), Expect = 2.212e-13 Identity = 71/268 (26.49%), Postives = 104/268 (38.81%), Query Frame = 3
Query: 453 VGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG-EVMGVWNTVNSIKTFKC-KEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP--PEIVFAKVAYEATTHGAQAEYKCKSRSTL 1241
VG + Y C G L G C + S P C+ ++ C P T + + + V C G+ +C N+ W C+ KSCG P NG YT++S C+ G RQCQ++ KWSG T C + C L P+NG + T +F+C K+G++L GS +R C +G WDG+ + C C P P + +G Y+CK T+
Sbjct: 57 VGTSIRYWCFPGTQLVGSAVITCMKSGDWSDKTPNCSPKS--CGD----PGTPANGRRSGQVYTFKSKVFFSCDRGHI--RVGPAFRQCQSNQKWSGVTPTCQPKSCGDPGTPANG-GRSGQVYTFKSKVFFSCDRG--------HIRVGPAFRQCQSNQKWSGVTPTCQPVDCGSLPTPKNGAKTEETKTTYQGRVSFRCVKKGHELKGSRVRVCQEDGRWDGTFTKCDPVECDDPGTPRFGGRNPDKDKYIYGDTVTYECKKNFTM 307 HSP 3 Score: 68.1662 bits (165), Expect = 2.514e-12 Identity = 69/268 (25.75%), Postives = 95/268 (35.45%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNE-WKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCR-RQCQADGKWSGDTAICTAILCPELSPPENGE--------VMGVWNTVNSIK--------------TFKCKEGYQLHGSHLRKCTREGNWDGSNSTC 1130
C P P NG + + +V ++C G+ GP R CQ+N + SG P C Q C P T + + + V C G+ +C N+ W C+ CG L PKNG TYQ +C E K R R CQ DG+W G C + C + P G + G T K +F C +G+QL G+ C GNW+ + TC
Sbjct: 97 CGDPGTPANGRRSGQVYTFKSKVFFSCDRGHIRVGPAFRQCQSNQKWSGVTPTC--QPKSCGD----PGTPANGGRSGQVYTFKSKVFFSCDRGHI--RVGPAFRQCQSNQKWSGVTPTCQPVDCGSLPTPKNGAKTEETKTTYQGRV--------SFRCVKKGHELKGSRVRVCQEDGRWDGTFTKCDPVECDDPGTPRFGGRNPDKDKYIYGDTVTYECKKNFTMRSNYEHGQSVSFGCNKGFQLKGASAIVCN-SGNWNDTIPTC 347
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Match: EDO36528 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIG6]) HSP 1 Score: 102.064 bits (253), Expect = 3.264e-23 Identity = 84/301 (27.91%), Postives = 120/301 (39.87%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAIC--------TAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETS 1256
C +D C V P NG S G TC GY L G + R CQA+ SG++ C + C P + + Q+ N ++ ++I C GY+ I + +G W P KC+ CG+L P NG+ + + TY S C++G+ + R CQA+G WSG C + I C P +G V G T S F C GY + GS +R C +W G+ C +CG + TT+ C + LIG S
Sbjct: 112 CSAVD--CGNLVNPANGETTGSSTTYGSTASVTCHEGYDLIGSKSRVCQADGTWSGNDTWCKGRE--CGPMPPLAHGQISGNGT--SYRT--VLRISCHPGYQFAGSDVSICQASG-LWSVIP-KCKVIDCGRLTVPLNGK-LEGSLTTYSSTINITCDEGYALIGPES--------RVCQANGTWSGSNVTCRGWFNTNPSLIDCGSPGAPAHGSVSGDSTTFTSRLAFSCDAGYIMSGSLIRTCLENASWSGTQPRCSAVDCGTLDSPANGIMRGSVTTYRGVVNITCDTGFHLIGSHS 393 HSP 2 Score: 100.908 bits (250), Expect = 9.639e-23 Identity = 101/416 (24.28%), Postives = 154/416 (37.02%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC--LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
C P P +G VG +V +TCK G+ L G R C + +G +P C + P H + + D + C +GY I C N W +C CG L +P NG T ++ TY S A C++G+ D K+ R CQADG WSG+ C C + P +G++ G + ++ C GYQ GS + C G W C V +CG + K+ TT+ + C LIG S V +G C + P +D + + D T + + C+ GY ++ ++ C N SW+ PRC C S +R + + C G+++
Sbjct: 1 CFDPGVPTHGRKMGVQYDVGSRVYFTCKHGFVLTGSSVRTCGPDFNWTGIQPTCKAVDCGYHNKP------AHGSVSGDSTTFTSRLVFSCDSGYI--MSGSPIRTCLENGSWSGTQPRCSAVDCGNLVNPANGETT-GSSTTYGSTASVTCHEGY------DLIGSKS--RVCQADGTWSGNDTWCKGRECGPMPPLAHGQISGNGTSYRTVLRISCHPGYQFAGSDVSICQASGLWS-VIPKCKVIDCGRLTVPLNGKLEGSLTTYSSTINITCDEGYALIGPES-----RVCQANGTWSGSNVTCRGWFNTNPSLIDCGSPGAPAHGS----VSGDSTTFTSRLAFSCDAGYIMSGSLIRTCLENASWSGTQPRCSAVDCGTL-DSPANGIMRGSVTTYRGVVNITCDTGFHL 388 HSP 3 Score: 70.8626 bits (172), Expect = 5.053e-13 Identity = 81/319 (25.39%), Postives = 126/319 (39.50%), Query Frame = 3
Query: 969 CPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFIPR-CVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWS 1916
C + P +G MGV V S F CK G+ L GS +R C + NW G TC +CG + V+ ++TT ++ + C S + G + TC E + SG +P+C VD + N +TT T+G+ C+ GY+L C +G+W+ C C PP + + + + ++ R CH GY A + I G W+ +P C+ C + P NG++ + ++ + C Y L GP+ VC NG WS
Sbjct: 1 CFDPGVPTHGRKMGVQYDVGSRVYFTCKHGFVLTGSSVRTCGPDFNWTGIQPTCKAVDCGYHNKPAHGSVSGDSTTFTSRLVFSCDSGYIMSG-SPIRTCLENGSWSG----TQPRC------SAVDCGNLVNPANGETTG----SSTTYGSTASVTCHEGYDLIGSKSRVCQADGTWSGNDTWCKGRECGPMPP-LAHGQISGNGTSYRTVLRISCHPGYQFA---------GSDVSICQASGLWSVIPK--CKVIDCGRLTVPLNGKL-------------EGSLTTYSSTINITCDEGYALIGPESRVCQANGTWS 279
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Match: EDO34701 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNM5]) HSP 1 Score: 98.5969 bits (244), Expect = 7.271e-23 Identity = 70/263 (26.62%), Postives = 105/263 (39.92%), Query Frame = 3
Query: 849 CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYI 1631
CNDGF++ + R CQ+DG WSG C A CP+ P G V+G+ +V F+C+EGY++ G C G+WD TC + +CG PP + + T+G++ +Y+C L G V G P CL + + N ++ T+G V CN G+ ++ C NG W P C A C P + + + + S Y C GY +
Sbjct: 11 CNDGFRLV--------GSATRTCQSDGLWSGLQPSCVAAACPDPVAPAKGLVVGLQRSVGDTVRFECQEGYRVSGKAYSVCQSSGSWDSPTPTCAIVDCGKPPALASGSIVGSVYTYGSKIQYRCIQDWHLSGPAE-----RVCQADGLWSGKAPVCL----------ERSCGNPGNLANGKRTGEDFTYGKVVTFTCNSGHVMSGSSTRTCQTNGKWTGTQPTCDPAICG--DPGAPVNGEKTGAFTYGSTLTYDCMPGYKL 248 HSP 2 Score: 93.9745 bits (232), Expect = 2.325e-21 Identity = 77/262 (29.39%), Postives = 107/262 (40.84%), Query Frame = 3
Query: 465 VEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGE 1250
V TC G+ L G R CQ++ SG +P C P P + R G+ V+ CQ GY K++ + + +G+ W C CGK +G ++ + YTY S IQ+ +C D R CQADG WSG +C C NG+ G T + TF C G+ + GS R C G W G+ TC CG P V + A T+G+ Y C L+G+
Sbjct: 7 VHITCNDGFRLVGSATRTCQSDGLWSGLQPSCVAAA---CPDPVAPAKGLVVGLQR---SVGDTVRFECQEGYRVSGKAYSVCQSSGS-WDSPTPTCAIVDCGKPPALASG-SIVGSVYTYGS-KIQY-------RCIQDWHLSGPAERVCQADGLWSGKAPVCLERSCGNPGNLANGKRTGEDFTYGKVVTFTCNSGHVMSGSSTRTCQTNGKWTGTQPTCDPAICGDPGAPVNGE-KTGAFTYGSTLTYDCMPGYKLVGD 251 HSP 3 Score: 84.7297 bits (208), Expect = 3.568e-18 Identity = 66/264 (25.00%), Postives = 101/264 (38.26%), Query Frame = 3
Query: 339 QLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTC 1130
+ C D GL + C PV P G VGD V + C+ GY + G CQ++ P C C P + + + + G ++ C + + + + +G W C ++SCG + NG+ ++TY + CN G + ++ R CQ +GKW+G C +C + P NGE G + T S T+ C GY+L G R C W GS C
Sbjct: 23 RTCQSDGLWSGLQPSCVAAACPDPVAPAKGLVVGLQRSVGDTVRFECQEGYRVSGKAYSVCQSSGSWDSPTPTCAIVD--CGKPPALASGSIVGSV----YTYGSKIQYRCIQDWHLSGPAERVCQADG-LWSGKAPVCLERSCGNPGNLANGKRT-GEDFTYGKVVTFTCNSGHVMSGSS--------TRTCQTNGKWTGTQPTCDPAICGDPGAPVNGEKTGAF-TYGSTLTYDCMPGYKLVGDRQRTCQANAQWTGSQPHC 269 HSP 4 Score: 65.855 bits (159), Expect = 7.183e-12 Identity = 51/190 (26.84%), Postives = 80/190 (42.11%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
+ C P +G S+ G +++Y C + L GP +R CQA+ SG P C +++ C + P + +DF G+ V C +G+ S + NG +W C+ CG P NG +TY S C G+K+ D+ +R CQA+ +W+G CT
Sbjct: 99 VDCGKPPALASGSIVGSVYTYGSKIQYRCIQDWHLSGPAERVCQADGLWSGKAPVCLERS--CGN----PGNLANGKRTGEDFTYGKVVTFTCNSGHVMSGSSTRTCQTNG-KWTGTQPTCDPAICGDPGAPVNGEK--TGAFTYGSTLTYDCMPGYKL------VGDR--QRTCQANAQWTGSQPHCTG 271 HSP 5 Score: 48.9062 bits (115), Expect = 2.917e-6 Identity = 68/306 (22.22%), Postives = 115/306 (37.58%), Query Frame = 3
Query: 1020 TVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQ 1925
+++S C +G++L GS R C +G W G +C+ C P V + G ++C+ + G+ ++ C SG P P C + VD K + I+ T+G+ ++ +C + L+ C +G W+ P C+E +C P ++ + + + C+ G+ ++ T T G WT PT C P C P P NGE K+ + + Y+C P Y+L G + C N W+ Q
Sbjct: 2 SLDSDVHITCNDGFRLVGSATRTCQSDGLWSGLQPSCVAAACPDPVAPAKGLVVGLQRSVGDTVRFECQEGYRVSGK-AYSVC----QSSGSWDSPTPTCAI------VDCGKPPALASGS----IVGSVYTYGSKIQYRCIQDWHLSGPAERVCQADGLWSGKAPVCLERSC-GNPGNLANGKRTGEDFTYGKVVTFTCNSGHVMS--GSSTRTCQT-------NGKWTGTQPT--CDPAICGDPGAPVNGE--------------KTGAFTYGSTLTYDCMPGYKLVGDRQRTCQANAQWTGSQ 266 HSP 6 Score: 48.521 bits (114), Expect = 3.721e-6 Identity = 33/104 (31.73%), Postives = 45/104 (43.27%), Query Frame = 3
Query: 258 NVKHLPNGCPSKACTANIDCWVEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQ 569
N H+ +G ++ C N W CD +CG P PVNG + G + Y C GY L G R+R CQAN + +GS+P CT +
Sbjct: 186 NSGHVMSGSSTRTCQTNGK-WTGTQP----TCDPAICG-----------DPGAPVNGEKTGA-FTYGSTLTYDCMPGYKLVGDRQRTCQANAQWTGSQPHCTGE 272
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Match: csmd2 (CUB and Sushi multiple domains 2 [Source:NCBI gene;Acc:101155284]) HSP 1 Score: 114.775 bits (286), Expect = 9.858e-26 Identity = 140/544 (25.74%), Postives = 211/544 (38.79%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGP--RKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDNSNRDDF--KNGED--VKIICQNGYEDPYKSHIIAKCNGN-EWKY-DP-IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDN---KSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMP------TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
+ C PV PVNG +G + Y C G+ L GP CQ + R S E P C L + P I ++ V R + +N D + ++C GY Y+ I +C N W Y DP C+ SCG L P NG + Y + AI CN G+ + + R+C ++G WSG C A C P NG+++G ++C G++L G +R C ++ W G C+ CG P F TT G Q + + T ++ G V + SG P P+C +++C +P V+++ + + + T V +CN GY L +C +G+W+ +P+C+ C P Y+ + S+ RY C G T+ C G W+ P + G + GE + +G VV++ C P Y LKG CL NG W Q P C+ I
Sbjct: 2523 MSCGMPVPPVNGSIAGQEFSLGAKATYQCNPGFRLSGPITTSLICQESGRWSPIEAPPRC-----LSVTCPDIGHSAVEHGRWRLIYGTQNQYDAMMMLVCDPGYY--YRGQRIIRCQENGTWNYPDPHPVCDIISCGDLGTPPNGNKI-GTLTVYGATAIFSCNTGYTLVGSR--------VRECMSNGLWSGTQVQCLAGHCGSPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGRTPVCVPITCGHPGNPTF------GTTQGTQ--FNLNDVVRFVCNTGYVLQGAVKSTCQASGQWSNPLPRCKIVNCTEPGHVENSIRQVLSSGA-------HRYSFQTTVSYRCNPGYYLLGTSSISCQGDGTWDRSLPKCLLMLCD-HPSVSPYAKISGDRRTVGSVIRYSCM----------GQRTVIGNTTRMCQLDGQWSGSPPHCSGESSGLCGDPGVPVHGIRLGEEFTVGS-----------------VVRFSCEPGYVLKGSSERTCLANGTWLNTQ-PECQVI 3006 HSP 2 Score: 113.235 bits (282), Expect = 3.019e-25 Identity = 118/502 (23.51%), Postives = 180/502 (35.86%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-CNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA-------LRKDGMETLSTIFDIKCNKGNWTKMPTEGCQX--------XXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRV 1841
C P PV+G VG V ++C+ GY LKG +R C AN ++PEC + P + +HD + C+ GY Y + ++ + C N W + +C +CG P NG + +++Y C+ GF + D+ C D W+G +C AI+C NG+V+G T S ++ C +GYQL + C GNW G C CG P + + + + C L+G G +P C+ D + N + F + G+ V C GY L I C N +W+ F P C+ CS P + SL + + Y C G+Y+A R DG + N+G K P Q + G LG+ L+ + +P+ NRV
Sbjct: 2950 CGDPGVPVHGIRLGEEFTVGSVVRFSCEPGYVLKGSSERTCLANGTWLNTQPECQVISCGNPGTPRNSHILIHDG-----LTFSRSITYSCREGY---YSTGLLTRHCTVNGTWTGNMPECSVINCGDPGVPANG-VRFGTDFSYNHTVSFQCSPGFTMDA------DRASTLICTKDRTWNGTKPLCKAIVCGPPPTIPNGQVVGTDFTWGSSISYSCNQGYQLSLPTVLTCQGNGNWSGEKPQCFPVFCGDPGTPAHGRREDRGFNYLSSVSFSCNHPLVLVGSAR-----RYCQYDGTWSGTQPSCIDPSHTTCSDPSTPLFGNQNNSQGFQI------GSTVFFNCRKGYLLQGSISRTCQPNLTWSGFQPECIAHHCSQPELPAQSDVKAIELPSLGYTLI--YTCQPGFYLAGGSEHRTCRSDGSWSGKAPLCAADNRGKIEKSPVGPVQEPPSKLPVPSGVFAKNSLWTGSYEYLGKKQPAMLSITAFEPLSNRV 3423 HSP 3 Score: 98.9821 bits (245), Expect = 8.018e-21 Identity = 116/439 (26.42%), Postives = 174/439 (39.64%), Query Frame = 3
Query: 348 VCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG--EVMGVWNTVNSIKT---FKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA-----RYYCHFGYY 1628
VCD CG DL P NG+ ++ + G ++C +GY L G R R C +N SG++ +C C S P V+ +++ V C G+ S I + + + W C +CG +P G T + + CN G+ +Q + CQA G+WS C + C E EN +V+ S +T ++C GY L G+ C +G WD S C++ C P +AK++ + T G+ Y C + T+IG T+ + ++D + W P P C D V +H + +E T G+ VR C GY L C NG+W N P C +C P + + S + L HD L Y C GYY
Sbjct: 2646 VCDIISCG------DLGTPP-----NGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGTQVQCL--AGHCGS----PEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQD-HRWSGRTPVCVPITCGHPGNPTFGTTQ-GTQFNLNDVVRFVCNTGYVLQGAV--------KSTCQASGQWSNPLPRCKIVNCTEPGHVENSIRQVLSSGAHRYSFQTTVSYRCNPGYYLLGTSSISCQGDGTWDRSLPKCLLMLCDHPSVSPYAKISGDRRTVGSVIRYSCMGQRTVIGNTTRMC--QLDGQ--WSGSP-PHCSGESSGLCGDPG-VPVH------GIRLGEEFTVGSVVRFSCEPGYVLKGSSERTCLANGTWLNTQPECQVISC-GNPGTPRNSHI----LIHDGLTFSRSITYSCREGYY 3040 HSP 4 Score: 86.2705 bits (212), Expect = 7.157e-17 Identity = 141/583 (24.19%), Postives = 216/583 (37.05%), Query Frame = 3
Query: 231 PECHVKSLDNVKHLPNG-----CPSKACTANIDCWVEY----DRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSC---GKLEDP-KNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRF-LSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWS 1916
P C + S ++ PNG TA C Y R + C+ + G + C P VNG V Y C G+ L G R C+ + R SG P C T P TQ F + V+ +C GY + + + C + +W +C+ +C G +E+ + + + Y++Q+ CN G+ + T+ CQ DG W C +LC S ++ G TV S+ + C + G+ R C +G W GS C + CG P V E T G+ + C+ L G +S TC + N + WL +P+C QV S N ++ ++HD +T + C GY + C NG+W +P C C P + + VRF ++ + C G+ + + ST+ K N TK C+ C PPT NG++ T T S + Y C+ Y+L P + C NG+WS
Sbjct: 2645 PVCDIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGTQVQCLAGHCGSPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGRTPVCVPITCGHPGNPTFGTTQ------GTQFNLNDVVRFVCNTGYV--LQGAVKSTCQASGQWSNPLPRCKIVNCTEPGHVENSIRQVLSSGAHRYSFQTTVSYRCNPGYYLLGTSSI--------SCQGDGTWDRSLPKCLLMLCDHPSVSPYAKISGDRRTVGSVIRYSCMGQRTVIGNTTRMCQLDGQWSGSPPHCSGESSGLCGDPGVPVHGIRLGEEFTVGSVVRFSCEPGYVLKG-SSERTC--LANGT-WL-NTQPEC-------QVISCGNPGTPRN--SHILIHDGLTFSRSITYSCREGYYSTGLLTRHCTVNGTWTGNMPECSVINCGD--PGVPANGVRFGTDFSYNHTVSFQCSPGFTMDADR-----ASTLICTKDRTWNGTK---PLCKAIVCGPPPTIPNGQVV------GTDFTWGS-------SISYSCNQGYQLSLPTVLTCQGNGNWS 3174 HSP 5 Score: 65.0846 bits (157), Expect = 2.583e-10 Identity = 102/441 (23.13%), Postives = 169/441 (38.32%), Query Frame = 3
Query: 729 EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQ--CTTDQFEDKNCRRQCQADGKWSGDTAI--CTAILCPEL--SPPENGE---VMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWD--GSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLL-HC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELPISWLYYRSDDKK 2000
+W C+ SCG P NG ++ ++ + A CN GF++ TT CQ G+WS A C ++ CP++ S E+G + G N +++ C GY G + +C G W+ + C + +CG T +GA A + C + TL+G + C +G + +CL HC P + + ++ I EN +++ +CN G+ L + C + W+ P CV C P + + T + + + R+ C+ GY L C G W+ P C+ CT+P +N S R L+ + + V Y C+P Y L G C +G W +P C ++ D +S S D++
Sbjct: 2512 QWNAPVPLCQVMSCGMPVPPVNG-SIAGQEFSLGAKATYQCNPGFRLSGPITTSLI--------CQESGRWSPIEAPPRCLSVTCPDIGHSAVEHGRWRLIYGTQNQYDAMMMLVCDPGYYYRGQRIIRCQENGTWNYPDPHPVCDIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVG-SRVREC----MSNGLWSGTQVQCLAGHCGSPEPIVNGQI-IGENYNYRGSVVY-----------QCNPGFRLIGVSVRICEQDHRWSGRTPVCVPITC-GHPGNPTFGTTQGTQFNLNDVVRFVCNTGY----------VLQGAVKSTCQASGQWSN-PLPRCKIVNCTEPGHVEN--------SIRQVLSSGAHRYSFQTTVSYRCNPGYYLLGTSSISCQGDGTWD-RSLPKCLLMLCDHPSVSPYAKISGDRR 2905
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Match: CSMD1 (CUB and Sushi multiple domains 1 [Source:NCBI gene;Acc:101164142]) HSP 1 Score: 114.39 bits (285), Expect = 1.248e-25 Identity = 110/447 (24.61%), Postives = 166/447 (37.14%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPEC--TDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAI---LCPELS-PPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAY-EATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL-----NSDILPACYNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C D G + + + C P P NG N + + D V +TC GY L G + C+ N + S P C + +D + + +H + F G V I C+ G+ S I+ + W +C SCG P N + ++TY S+ + C N R CQ DG WSG CT +C + PP + G S+ F C+ GY L GS R C G W G+ C +CG P ++ + T G Y C +TS LT W +P ++ C + +Y + ++ T V +CN G+ + SD++ G+WN P C C PP + Y V L S Y C GY +++
Sbjct: 2581 VRICQQDHRWSGTTPVCVPITCGHPGNPPNGRTNGTEFNLNDVVNFTCNKGYILSGSPRAQCRLNGQWSSPLPVCKVVNCSDPGHVENGVRQSGLH---YPEVFSYGVTVAIHCKRGFY-LLGSAILTCQHDGLWDRPMPRCLAISCGDPGVPPNAVVLGTRSWTYGSV--------LQYSCLPSGLLVGNSTRHCQEDGTWSGVPPYCTGASVGICGDPGIPPHGSRLGGEEFKTKSLLRFSCEAGYSLIGSAERTCLHNGTWSGTQPVCQAVSCGNPGTPAHGRIVLNDGITFGNSVAYACLEGF----KTSGLTTRHCTTNGTWTGQPPDCTVISCGDPGPIANGIY-----------LGNDFTFNHTVVYRCNPGHLMEPSGPGSDVIRCSKEGTWNQTKPSCKVIQCGP-PPQVLYGKVEGSDLSWGSSVSYNCFHGYQLSI 2999 HSP 2 Score: 104.76 bits (260), Expect = 1.367e-22 Identity = 110/427 (25.76%), Postives = 165/427 (38.64%), Query Frame = 3
Query: 414 QPVNGHA-NHSILLVGDQVEYTCKSGYALKGPRKRYCQAN----LRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYE-DPYKSHIIAKCNGNEWK--YDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDG--FKIQCTTDQFEDKNCRR-QCQADGKWSG--DTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARY------YCHFGYYI 1631
P+NG N + L G +++Y C GY L G C+ N + P C Q C IP + + + + F G V C GY DP W P +C C +E T+ +++ T++ + G ++C++ + R C A+G W G D A C I C EL P G +G T + F C GY L GSH+R+C +G W G+ + C+ +C P IV ++ + +++ Y+C LIG TS C + SG P C P + T F ++D V CN GY L+ C NG W+ +P C CS P + VR L + + Y +C G+Y+
Sbjct: 2300 SPLNGGVVNRTKLSPGSRIQYFCNRGYYLVGSSNATCRLNSNGLYKWDSPPPFC--QAISC----GIPLSPGNGSFHATQFTVGSQVTYYCSQGYHLDPAVPMTAVCLEDGSWSNSLSPPRCLPVHCPSIE------TILSDHMTFRLLRGILGEFGSMVMLECSSGYYLGAGYRTLHCLANGTWEGSDDPATCKIISCGELPSPPFGTKLGTLTTFGATTIFMCNHGYTLVGSHVRECGADGLWSGAETRCLAGHCDSPDPIVNGHISGDGSSYRDTVVYQCMLGYRLIG-TSVRICQQDHRWSGTTPV--------CVPITCGHPGNPPNGRTNGTEFNLNDVVNF------TCNKGYILSGSPRAQCRLNGQWSSPLPVCKVVNCSD--PGHVENGVRQSGLHYPEVFSYGVTVAIHCKRGFYL 2697 HSP 3 Score: 80.1073 bits (196), Expect = 5.604e-15 Identity = 129/542 (23.80%), Postives = 193/542 (35.61%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECT----DQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG---------EVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG----PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHP--LYRLKGPK---IAVCLNGHWSPPQMPTCEFI 1946
+ C P G ++ G + C GY L G R C A+ SG+E C D D P H + + ++ + V C GY S I + + + W C +CG +P NGRT + + CN G+ + + R QC+ +G+WS +C + C + ENG EV TV CK G+ L GS + C +G WD C+ +CG PP +V ++ T+G+ +Y C L+G ++ C E SG P + C + H + + +E + +R C GY L C +NG+W+ P C +C V + + Y C G+ + G+ T G WT P + C C P NG IYL +D T N V Y C+P L GP I G W+ + P+C+ I
Sbjct: 2484 ISCGELPSPPFGTKLGTLTTFGATTIFMCNHGYTLVGSHVRECGADGLWSGAETRCLAGHCDSPD--------PIVNGHISGDGSSYR--DTVVYQCMLGYRLIGTSVRICQQD-HRWSGTTPVCVPITCGHPGNPPNGRTN-GTEFNLNDVVNFTCNKGYILSGSP--------RAQCRLNGQWSSPLPVCKVVNCSDPGHVENGVRQSGLHYPEVFSYGVTV----AIHCKRGFYLLGSAILTCQHDGLWDRPMPRCLAISCGDPGVPPNAVVLGTRSW---TYGSVLQYSCLPSGLLVGNST-RHCQEDGTWSGVPPYCTGASVGICG-----DPGIPPHGSR-----LGGEEFKTKSLLRFSCEAGYSLIGSAERTCLHNGTWSGTQPVCQAVSCGNPGTPAHGRIVLNDGITFGNSVAYACLEGF----KTSGLTTRHCT-----TNGTWTGQPPD-CTVISCGDPGPIANG-IYL--GNDFT----------FNHTVVYRCNPGHLMEPSGPGSDVIRCSKEGTWNQTK-PSCKVI 2963 HSP 4 Score: 67.3958 bits (163), Expect = 4.202e-11 Identity = 79/331 (23.87%), Postives = 122/331 (36.86%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALK--GPRKRY--CQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAIL---CPELSPPENG-EVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAK 1358
+ C P NG + V Y C G+ ++ GP C + ++P C + C P + Y +V + D G V C +GY+ + + + NG W + +C +K C N S+ ++ C + C + R CQADG WSG+ C C + P G V+ V S +FKC++ Y + GS R C W G+ C+ +C P V + + T G Y C+ L G + TC + D + W KP CK ++ S K
Sbjct: 2901 ISCGDPGPIANGIYLGNDFTFNHTVVYRCNPGHLMEPSGPGSDVIRCSKEGTWNQTKPSC--KVIQCGPPPQVLYGKVEGS----DLSWGSSVSYNCFHGYQLSIPAVLTCEGNGT-WTGEVPQCLRKLC-------------INTEALISMRVRVCRSEVRFYCHAPHVLVGSASRLCQADGIWSGEQPACIDPAFNSCRDPGTPAYGIPVVAQGFQVGSKISFKCRKNYHILGSTTRTCLENLTWSGTQPECVAHSCRQPETPTNVDVRSMDLPTLGYTLLYTCQEGFYLSGGSEHRTC-KSDGR--WSGKPP-----LCKGMEIQSQK 3203
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Match: csmd2 (CUB and Sushi multiple domains 2 [Source:NCBI gene;Acc:101155284]) HSP 1 Score: 109.768 bits (273), Expect = 3.684e-24 Identity = 102/418 (24.40%), Postives = 156/418 (37.32%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAK-CNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACS--ARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIA 1634
C P PV+G VG V ++C+ GY LKG +R C AN ++PEC + P + +HD + C+ GY Y + ++ + C N W + +C +CG P NG + +++Y C+ GF + D+ C D W+G +C AI+C NG+V+G T S ++ C +GYQL + C GNW G C CG P + + + + C L+G G +P C+ D + N + F + G+ V C GY L I C N +W+ F P C+ CS P + SL + + Y C G+Y+A
Sbjct: 2917 CGDPGVPVHGIRLGEEFTVGSVVRFSCEPGYVLKGSSERTCLANGTWLNTQPECQVISCGNPGTPRNSHILIHDG-----LTFSRSITYSCREGY---YSTGLLTRHCTVNGTWTGNMPECSVINCGDPGVPANG-VRFGTDFSYNHTVSFQCSPGFTMDA------DRASTLICTKDRTWNGTKPLCKAIVCGPPPTIPNGQVVGTDFTWGSSISYSCNQGYQLSLPTVLTCQGNGNWSGEKPQCFPVFCGDPGTPAHGRREDRGFNYLSSVSFSCNHPLVLVGSAR-----RYCQYDGTWSGTQPSCIDPSHTTCSDPSTPLFGNQNNSQGFQI------GSTVFFNCRKGYLLQGSISRTCQPNLTWSGFQPECIAHHCSQPELPAQSDVKAIELPSLGYTLI--YTCQPGFYLA 3306 HSP 2 Score: 106.686 bits (265), Expect = 3.703e-23 Identity = 141/561 (25.13%), Postives = 214/561 (38.15%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGP--RKRYCQANLRLSGSE--PECTDQTDLCFSAPYIPYTQVHDNSNRDDF--KNGED--VKIICQNGYEDPYKSHIIAKCNGN-EWKY-DP-IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAIL----------CPELS-------PPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDN---KSGWLPKPEPKC-LLHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCN-KGNWTKMP------TEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
+ C PV PVNG +G + Y C G+ L GP CQ + R S E P C L + P I ++ V R + +N D + ++C GY Y+ I +C N W Y DP C+ SCG L P NG + Y + AI CN G+ + + R+C ++G WSG C L CP ++ P NG+++G ++C G++L G +R C ++ W G C+ CG P F TT G Q + + T ++ G V + SG P P+C +++C +P V+++ + + + T V +CN GY L +C +G+W+ +P+C+ C P Y+ + S+ RY C G T+ C G W+ P + G + GE + +G VV++ C P Y LKG CL NG W Q P C+ I
Sbjct: 2473 MSCGMPVPPVNGSIAGQEFSLGAKATYQCNPGFRLSGPITTSLICQESGRWSPIEAPPRC-----LSVTCPDIGHSAVEHGRWRLIYGTQNQYDAMMMLVCDPGYY--YRGQRIIRCQENGTWNYPDPHPVCDIISCGDLGTPPNGNKI-GTLTVYGATAIFSCNTGYTLVGSR--------VRECMSNGLWSGTQVQCLVQLFTEKHSKHSFCPYIAGHCGSPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGRTPVCVPITCGHPGNPTF------GTTQGTQ--FNLNDVVRFVCNTGYVLQGAVKSTCQASGQWSNPLPRCKIVNCTEPGHVENSIRQVLSSGA-------HRYSFQTTVSYRCNPGYYLLGTSSISCQGDGTWDRSLPKCLLMLCD-HPSVSPYAKISGDRRTVGSVIRYSCM----------GQRTVIGNTTRMCQLDGQWSGSPPHCSGESSGLCGDPGVPVHGIRLGEEFTVGS-----------------VVRFSCEPGYVLKGSSERTCLANGTWLNTQ-PECQVI 2973 HSP 3 Score: 104.375 bits (259), Expect = 1.691e-22 Identity = 122/456 (26.75%), Postives = 182/456 (39.91%), Query Frame = 3
Query: 348 VCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQ--TDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCN---------------GNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENG--EVMGVWNTVNSIKT---FKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLA-----RYYCHFGYY 1628
VCD CG DL P NG+ ++ + G ++C +GY L G R R C +N SG++ +C Q T+ + PY H S + NG+ II +N Y Y+ ++ +CN + W C +CG +P G T + + CN G+ +Q + CQA G+WS C + C E EN +V+ S +T ++C GY L G+ C +G WD S C++ C P +AK++ + T G+ Y C + T+IG T+ + ++D + W P P C D V +H + +E T G+ VR C GY L C NG+W N P C +C P + + S + L HD L Y C GYY
Sbjct: 2596 VCDIISCG------DLGTPP-----NGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGTQVQCLVQLFTEKHSKHSFCPYIAGHCGS-PEPIVNGQ---IIGEN-YN--YRGSVVYQCNPGFRLIGVSVRICEQDHRWSGRTPVCVPITCGHPGNPTFGTTQ-GTQFNLNDVVRFVCNTGYVLQGAV--------KSTCQASGQWSNPLPRCKIVNCTEPGHVENSIRQVLSSGAHRYSFQTTVSYRCNPGYYLLGTSSISCQGDGTWDRSLPKCLLMLCDHPSVSPYAKISGDRRTVGSVIRYSCMGQRTVIGNTTRMC--QLDGQ--WSGSP-PHCSGESSGLCGDPG-VPVH------GIRLGEEFTVGSVVRFSCEPGYVLKGSSERTCLANGTWLNTQPECQVISC-GNPGTPRNSHI----LIHDGLTFSRSITYSCREGYY 3007 HSP 4 Score: 62.3882 bits (150), Expect = 1.552e-9 Identity = 64/276 (23.19%), Postives = 95/276 (34.42%), Query Frame = 3
Query: 321 VEYDRAQLCVC--DSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLHG-SHLRKCTREGNWDGSNSTC 1130
++ DRA +C D G + + C PP NG + G + Y+C GY L P CQ N SG +P+C C P T H F V C + + + +G P I +C P G + + S C G+ +Q + R CQ + WSG C A C + P +V + ++ + C+ G+ L G S R C +G+W G C
Sbjct: 3066 MDADRASTLICTKDRTWNGTKPLCKAIVCGPPPTIPNGQVVGTDFTWGSSISYSCNQGYQLSLPTVLTCQGNGNWSGEKPQCFPV--FCGD----PGTPAHGRREDRGFNYLSSVSFSCNHPLVLVGSARRYCQYDGTWSGTQPSCIDPSHTTCSDPSTPLFGNQNNSQGFQIGSTVFFNCRKGYLLQ--------GSISRTCQPNLTWSGFQPECIAHHCSQPELPAQSDVKAIELPSLGYTLIYTCQPGFYLAGGSEHRTCRSDGSWSGKAPLC 3327 HSP 5 Score: 59.3066 bits (142), Expect = 1.343e-8 Identity = 48/189 (25.40%), Postives = 69/189 (36.51%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGN-EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
C P P +G V ++C L G +RYCQ + SG++P C D + S P P +NS F+ G V C+ GY + I C N W +C C + E P + I C GF + ++ R C++DG WSG +C
Sbjct: 3152 CGDPGTPAHGRREDRGFNYLSSVSFSCNHPLVLVGSARRYCQYDGTWSGTQPSCIDPSHTTCSDPSTPLFGNQNNSQ--GFQIGSTVFFNCRKGYL--LQGSISRTCQPNLTWSGFQPECIAHHCSQPELPAQSDVKAIELPSLGYTLIYTCQPGFYLAGGSEH-------RTCRSDGSWSGKAPLCAG 3329
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Match: csmd3a (CUB and Sushi multiple domains 3 [Source:NCBI gene;Acc:101161736]) HSP 1 Score: 105.916 bits (263), Expect = 6.995e-23 Identity = 121/503 (24.06%), Postives = 170/503 (33.80%), Query Frame = 3
Query: 378 CMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQF----------------------------------------------------EDKNCRRQCQADGKWSGDTAICTAILCPELSPP--ENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWNFI-PRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWT-KMPT 1715
C+ +D C P P NG + G V Y+C G LKG R CQ N S P C+ P IP + + DFK V C GYE S + NG W C+ CG P NGR + T+ I C DG+ + T + ED + R C +G WSG ICTA+ C LSPP NG + G S ++ C GY+L + C G W G C+ + CG P V + + ++ + C L+G T+ C SG +P+C+ + + N+T F + G+ V C G+ + C + +W+ P C+ AC + V Y C GY++A G E + N G WT KMP
Sbjct: 2765 CIVVD--CGHPGSPPNGALSGDKFTFGSTVRYSCLGGRQLKGESSRTCQLNGMWSFPMPFCSGDIAGSCGDPGIP---AQGSREQTDFKIRSKVHFTCSEGYELIGSSERMCFPNGT-WSGTQPFCKPVQCGNPGTPSNGRVFRLDGTTFSHSVIYSCMDGYILTGPTTRLCQANGTWSGAQPNCTMINCGDPGVPANGLRYGEDFTIGQNVTFQCQPGYRMEEDGSPVRMCTHNGTWSGSMPICTAVTC--LSPPAISNGALQGSDFEWGSSVSYSCSPGYELSFPAVLTCVSNGTWSGMLPQCLPKFCGDPGTPVGGSREGRSFIYQSEVSFSCSPPLILVG-TATRRCESDGTWSG----TQPRCIEPTRTSCENPGTPRYGSLNRTFGFKV------GSIVSFHCQPGHLIQGSSSRTCQPDLTWSGTQPECIPHACKQPESPLHVDVVGMDLPGFGYTLVYSCQHGYFLA---GGSE-----HRVCKNDGTWTGKMPV 3240 HSP 2 Score: 104.76 bits (260), Expect = 1.574e-22 Identity = 107/444 (24.10%), Postives = 173/444 (38.96%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNS-NRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAIL---CPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKV-AYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKC-LLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPA---CYNGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIAL 1637
++C+ D+ G + + I + C P P+ G + + + V + C GY ++GP CQAN + + P C + C S P IP + + +F G V C GY + S ++ +W +C CG P NG + + +T+ S C G +++ + R CQ +G WS C+ + C + P G + S F C EGY+L GS R C G W G+ C CG P +V + TT Y C L G T+ L +G +P C +++C V + + E + T G +V +C GY + D P +NG+W+ +P C C + PP++ ++ + S Y C GY ++
Sbjct: 2629 VRICLQDNQWSGQLPICIPISCGHPGSPIYGRTVGNGYNLNNVVSFVCNRGYEMEGPAHAQCQANRQWNHPPPTC--KVVNC-SDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYL-FGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNG-ALSGDKFTFGSTVRYSCLGGRQLKGESS--------RTCQLNGMWSFPMPFCSGDIAGSCGDPGIPAQGSREQTDFKIRSKVHFTCSEGYELIGSSERMCFPNGTWSGTQPFCKPVQCGNPGTPSNGRVFRLDGTTFSHSVIYSCMDGYILTGPTTRLC-----QANGTWSGAQPNCTMINCGDPGVPANGLRYGE-----------DFTIGQNVTFQCQPGYRMEEDGSPVRMCTHNGTWSGSMPICTAVTCLS-PPAISNGALQGSDFEWGSSVSYSCSPGYELSF 3042 HSP 3 Score: 97.4413 bits (241), Expect = 2.825e-20 Identity = 149/583 (25.56%), Postives = 219/583 (37.56%), Query Frame = 3
Query: 369 GLVCMEIDLQCQPPVQPVNGH-ANHSILLVGDQVEYTCKSGYALKGPRKRYCQANL----RLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGY--------------EDPYKSH-IIAKCNGNEW---KYDPIKC---------EKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCG----PPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCV-EAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDE--LPISWLYYRSD 1991
G + + C P P++G ++ S V V + C GY L G C+ S P C Q C P P ++ D+ G V C +GY + + +H I +C+G W K D + C CG E NG+ + N+ Y+ + C GF++ ++ R C D +WSG IC I C P G +G +N++ +F C GY++ G +C W+ TC V NC P I +K+ + T G Y C L G + LTC +G KP P+C++ VD H + + D+ T G+ VR C G +L + C NG W+F +P C + A S P + R + D R HF +G E + + + G W+ C+P +C P TP NG ++ L D T + I Y C Y L GP +C NG WS Q P C I + +P + L Y D
Sbjct: 2435 GFRIRYVAMYCSTPDSPLHGSISSQSGGHVNSVVRWACDRGYRLIGNATGTCRRTPLGYHAWDSSVPAC--QAVSC--GP--PKAPINGAVLASDYSVGTRVSYFCNDGYRLSSKEVTSAICQPDGTWSNHNKIPRCSG--WIFLKLDFVVCPSIGSFSLEHAGHCGIPEGIVNGQVI-GENFGYRDTVVYQCLPGFRLIGSS--------VRICLQDNQWSGQLPICIPISCGHPGSPIYGRTVGNGYNLNNVVSFVCNRGYEMEGPAHAQCQANRQWNHPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFG-SPVLTC----QPTGQWDKPLPECIV------VDCG----HPGSPPNGALSGDKFTFGSTVRYSCLGGRQLKGESSRTCQLNGMWSFPMPFCSGDIAGSCGDPGIPAQGSR---EQTDFKIRSKVHF-----TCSEGYELIGSSERMCFPNGTWSGT-QPFCKPVQCGNPGTPSNGRVFRL---DGTTFSHSVI---------YSCMDGYILTGPTTRLCQANGTWSGAQ-PNCTMINCGDPGVPANGLRYGED 2963 HSP 4 Score: 58.5362 bits (140), Expect = 2.411e-8 Identity = 65/269 (24.16%), Postives = 94/269 (34.94%), Query Frame = 3
Query: 336 AQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDP--IKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGV-WNTVNSIKTFKCKEGYQLH-GSHLRKCTREGNWDGSNSTC 1130
++C + G + + + C P NG S G V Y+C GY L P C +N SG P+C + C P T V + F +V C + + +G P I+ + SC P+ G + SI C G IQ ++ R CQ D WSG C C + P + +V+G+ + C+ GY L GS R C +G W G C
Sbjct: 2987 VRMCTHNGTWSGSMPICTAVTCLSPPAISNGALQGSDFEWGSSVSYSCSPGYELSFPAVLTCVSNGTWSGMLPQCLPK--FCGD----PGTPVGGSREGRSFIYQSEVSFSCSPPLILVGTATRRCESDGTWSGTQPRCIEPTRTSCENPGTPRYGSLNRTFGFKVGSIVSFHCQPGHLIQGSSS--------RTCQPDLTWSGTQPECIPHACKQPESPLHVDVVGMDLPGFGYTLVYSCQHGYFLAGGSEHRVCKNDGTWTGKMPVC 3241 HSP 5 Score: 51.9878 bits (123), Expect = 2.282e-6 Identity = 47/221 (21.27%), Postives = 82/221 (37.10%), Query Frame = 3
Query: 321 VEYDRAQLCVCDSYLCGLVCMEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRD-DFKNGEDVKIICQNGYEDPYKSHIIAKCNGN------EWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTA 962
+ + CV + G++ + C P PV G + +V ++C L G R C+++ SG++P C + T P P + + NR FK G V CQ G H+I + W +C +C + E P + + + + + C G+ + ++ R C+ DG W+G +C A
Sbjct: 3040 LSFPAVLTCVSNGTWSGMLPQCLPKFCGDPGTPVGGSREGRSFIYQSEVSFSCSPPLILVGTATRRCESDGTWSGTQPRCIEPTRTSCENPGTPR---YGSLNRTFGFKVGSIVSFHCQPG-------HLIQGSSSRTCQPDLTWSGTQPECIPHACKQPESPLHVDVVGMDLPGFGYTLVYSCQHGYFLAGGSEH-------RVCKNDGTWTGKMPVCRA 3243
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Match: svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:101171700]) HSP 1 Score: 105.145 bits (261), Expect = 1.133e-22 Identity = 110/429 (25.64%), Postives = 168/429 (39.16%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGS-WN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGY------YIALRKDG 1649
I +C+ P P +G N + VG V Y+C+ GY LKG R C + + P C + C + I H DF E + C G+ S IA +W CE CG P + T+ YTY S C GF ++ + CQADG WS ++ C C + SP +G MG NS ++C GY+L G C +G WD C + +C PP +I + + + EY C ++G+ L C G +P+ +P C+ C V KV + G ++ +C+ GY+L C G W+ +P C CS+ PP + + ++ ++ A Y C GY +++ +DG
Sbjct: 2534 IPAECETPPNPEHGWVNVTDASVGSIVTYSCERGYELKGESVRQCISGHLWTSDAPTCHPIS--CDNPGPIDNGTTHGV----DFVYLEVMHFECDPGFVL-RGSDTIACLADGKWNGQKPLCEPVLCGPPIVPSD-VTVEGKEYTYNSRIELSCPPGFVLKGMSVHV--------CQADGTWSHESPTCIPARCSKPSPIPHGHYMGSEFGYNSKVKYECDRGYKLSGDPTLVCKSDGLWDKPVPRCDIISCDPPEDISHGFLNGSSFNYNDVVEYVCFDGYEIVGD-PVLRCSYEGLWLGSVPECQP-CV--CALPGVKFGKV------------LSSGHACGDRLQFQCDKGYKLLGPSQATCEKGGVWSPGVPMCSRGRCSSPPPVVPNAVLQGDTVTLLDTAIYKCRPGYQRKGPLFVSCGRDG 2930 HSP 2 Score: 100.908 bits (250), Expect = 2.121e-21 Identity = 127/518 (24.52%), Postives = 189/518 (36.49%), Query Frame = 3
Query: 435 NHSILLVGDQ----VEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKC-NGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKT-----TNFIMHDEVTHGTHVRAKCNFGYELNSDILPACY-NGSWN-FIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIM 1949
NH +L D VE +C+ GY L+G + C + + + P C + C P I + + V C +G+ +K C +W +C C + + NG + Y S A+ C G+ + N C G W G C I CP NG+V T+ C G++L G + KC GNWD C+ +C PP I V + + G Y C L+G+ LTC EV S C L P +D Y+ + T T + HGT + +C+ GYE+ C NG WN P C+ A C PP+ ++ V S+ Y C GY L+ + + +C G+ C P C P NG T + ++ V+ +EC P + L+G CL +G W+ Q P CE ++
Sbjct: 2182 NHMVLKRLDYESGIVELSCEIGYVLEGAQIIRCTPSQEWNDTFPVC--KQVFCGPPPEISFGAPSSSPPFSFSSV---VTYTCMDGFS--FKKEDFVSCLVSGQWSTPYPECIPVECPQPVEISNG-IVDVQGLMYLSKALYTCKSGYNLV--------GNSTVLCGERGIWIGGVPSCRPIECPIPKQVANGKVAYRKLQFGHSATYSCHRGFRLEGPEMVKCLANGNWDLEPPNCVQISCTPPKAIENGFVEGQDHSFGVTIFYSCFPGFQLVGQ-DHLTCEEVGWSSSVPVCVPSDCGL---PPHIDFGD-YVRVTDSTSIDALTAAPLDLNFLHGTLIEYRCHKGYEITFHTRLMCQENGGWNGTAPSCIPAECET-PPNPEHGWVNVTDASVGSIVTYSCERGY--ELKGESVR--------QCISGHLWTSDAPTCHPISCDNPGPIDNG-------------TTHGVDFVYLEVMHFECDPGFVLRGSDTIACLADGKWN-GQKPLCEPVL 2653 HSP 3 Score: 98.5969 bits (244), Expect = 1.125e-20 Identity = 126/528 (23.86%), Postives = 204/528 (38.64%), Query Frame = 3
Query: 405 PPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSC---GKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKW--SGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRN---CGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCK-PFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNG-SW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKG-NWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFI 1946
PPV P ++ L+ D Y C+ GY KGP C + + EP + C P I + QV + D+F + C +GYE + ++ + W IKC C L DP + T I F C GF +Q + +CQ G W S T C ++C + P +G + G + + C G+ + G ++ C + W+G+ C+ + CGPPP + A+ A +H Y C + L+G + LTC + + + LP P + C P Q+ +V H I++ E + +C+ G+ L D L C G +W + P C +C PP + ++ R + S +Y G + + + + I C WT + + C+ C P NG + + + D V Y C+ Y ++G + C NG W+PP PTC +
Sbjct: 2889 PPVVPNAVLQGDTVTLL-DTAIYKCRPGYQRKGPLFVSCGRDGQWG--EPRIRCEAVNCGKPPAILHAQVLE----DNFTFPNKITYRCDDGYELATLAASLSCQSDGTWSKRNIKCHPTPCLLPSNLSDPH--LVVSGRKLTPVGDTITFSCPPGFYLQ--------GSALAECQVGGIWAPSISTVFCKMVVCEKPPPLLHGVIKGDSYNYGDLVLYSCLPGFDMKGEAVQTCQADRKWNGTQPVCVASSEYACGPPPTVSHAQFRITAESHLLNVSYLCNAGMQLVGPET-LTC--LADGTWSLPAPTCEVARGCDGPVQLVHGRVQDH--------ILNSE----RALEFQCDKGFSLVGDHLVVCLGGNTWSSAFPTCQPKSCPP-PPGWRGNSSRSVG----SHQEFY--VGQSVPVSCPKGQKVKGSGSITCRPDQTWTSV-SSVCERVPCGPPLHVANGVV----RGAVFQFGD---------VAVYSCYAGYTMEGVGRSRCQENGTWTPP--PTCRAV 3361 HSP 4 Score: 96.2857 bits (238), Expect = 5.858e-20 Identity = 136/553 (24.59%), Postives = 207/553 (37.43%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTD------------------QFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPE----PKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGS-WNFIP---RCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNW-TKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVC-LNGHWSPPQMPTCEFIMHDELPI 1967
+ C P NG + G V Y C +G+ L G + YC N + G P C D + + D KN D IC + PY + K +KC+ P+ G + +N+ S + C++G+K+ ++ Q + + C+ +G+WS C +I C + ++ +G + + + CKEGY L G R+C G W S++ C+ R+CGPPP I A+ +G A Y C + G T+ V N G P+ P+C+ + P +D + +K + T V KC G+ N+ C G W P C+ CS +P S+++ V + ++ Y C G+ I R + T G W +P C P C+ PP +NG I R+ LT KS V Y C YRL G VC N WS + PTC + PI
Sbjct: 1631 VSCGRPHPLENGLFQGADFHAGSSVVYQCNAGFYLLGDARVYCSNNGKWGGHPPACLDVDECALGS---------DCDTHASCKN-TDGSYICTCIH--PYT---------GDGKNCTVKCQNPG-----SPEFGHRV-GSNFLMGSQVVFSCDEGYKLYGSSKLRCLESGVWDDPVPIVLLQRPQGSMKVVCEENGEWSRPVPRCVSIKCSQPPALKDAITVGENFEMGNKVHYVCKEGYTLIGPESRECLLTGQWSESSAQCVPRSCGPPPAIDHAEPYESHQLYGDTANYYC-----IDGYTASNNSKMVCNAQGVWAPPDGLEVPRCIANFCPRPLDLPHAILDAVSKP-------KYPTNTEVIYKCEEGFMPNTTASLRCLMGGIWEPSPFEISCIPVRCS-KPESIEHGYVAETNYSFGAVVAYSCDPGFMI--RGEKRRTCQA-------NGEWGGALPV--CMPVTCSSPPLLRNGYI-----KTRSGLTFKS-------KVTYACREGYRLDGRPERVCQANRKWSSQETPTCVLLTCKPPPI 2120 HSP 5 Score: 93.9745 bits (232), Expect = 2.891e-19 Identity = 128/525 (24.38%), Postives = 203/525 (38.67%), Query Frame = 3
Query: 387 IDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSG-DTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVF-AKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHC-KPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYEL--NSDILPACYNGSW-NFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
I ++C P +G+ + G V Y+C G+ ++G ++R CQAN G+ P C T C S P + + S FK+ V C+ GY + + + N + C +C P +Y + +Q+ CN+G+++ DKN G W C+ + CPE EN V+ + + I C+ GY L G+ + +CT W+ + C CGPPPEI F A + + + Y C + E F++C SG P P+C+ + C +P ++ + V + + + + C GY L NS +L G W +P C C P + V + L+ A Y CH G+ R +G E + + + GNW P C CT P +NG ++ GQ +T + Y C P ++L G C WS +P C
Sbjct: 1993 IPVRCSKPESIEHGYVAETNYSFGAVVAYSCDPGFMIRGEKRRTCQANGEWGGALPVCMPVT--CSSPPLLRNGYIKTRSGLT-FKS--KVTYACREGYRLDGRPERVCQANRKWSSQETPTCVLLTCKP--PPIIPHGVYKGSDFQVGHKVQYVCNEGYELSGDAIWTCDKN--------GTWDKMKPPRCSPVKCPEPLLEENHMVLKRLDYESGIVELSCEIGYVLEGAQIIRCTPSQEWNDTFPVCKQVFCGPPPEISFGAPSSSPPFSFSSVVTYTCMDGFSFKKE-DFVSC----LVSGQWSTPYPECIPVECPQPVEISNGIVDVQ------------GLMYLSKALYTCKSGYNLVGNSTVLCG-ERGIWIGGVPSCRPIECPI-PKQVANGKVAYRKLQFGHSATYSCHRGF----RLEGPEMVKCLAN-----GNWDLEPPN-CVQISCTPPKAIENG--FVEGQDHSFGVT-----------IFYSCFPGFQLVGQDHLTCEEVGWS-SSVPVC 2459 HSP 6 Score: 93.9745 bits (232), Expect = 3.150e-19 Identity = 136/590 (23.05%), Postives = 211/590 (35.76%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKI------QCTTD------------------------------------QFE-DKN------CRRQCQADGKWSGDTAICTAILCPELSPP---ENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPK-CLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSA----RPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCL-NGHWSPPQMPTCEFIMHDELPISWLYYRSDD 1994
C PP+ P + ++E +C G+ LKG CQA+ S P C C IP H + +F VK C GY+ ++ K +G W +C+ SC ED +G + +++ Y + C DG++I +C+ + QF+ DK + C+ G WS +C+ C SPP N + G T+ +KC+ GYQ G C R+G W C NCG PP I+ A+V + T + Y+C L + L+C S K P CLL P + + + T + D +T C G+ L L C G + P C +PP + + ++ S + L Y C G+ ++ + ++T K N T+ C PPT + + + +S H V Y C+ +L GP+ CL +G WS P PTCE + P+ ++ R D
Sbjct: 2654 CGPPIVPSDVTVEGKEYTYNSRIELSCPPGFVLKGMSVHVCQADGTWSHESPTCIPAR--CSKPSPIP----HGHYMGSEFGYNSKVKYECDRGYKLSGDPTLVCKSDG-LWDKPVPRCDIISCDPPEDISHG-FLNGSSFNYNDVVEYVCFDGYEIVGDPVLRCSYEGLWLGSVPECQPCVCALPGVKFGKVLSSGHACGDRLQFQCDKGYKLLGPSQATCEKGGVWSPGVPMCSRGRCS--SPPPVVPNAVLQGDTVTLLDTAIYKCRPGYQRKGPLFVSCGRDGQWGEPRIRCEAVNCGKPPAILHAQVLEDNFTFPNKITYRCDDGYELATLAASLSCQSDGTWSKRNIKCHPTPCLL---PSNLSDPHLVVSGRKLTP---VGDTITF------SCPPGFYLQGSALAECQVGGI-WAPSISTVFCKMVVCEKPPPLLHGVIKGDSYNYGDLVLYSCLPGF--DMKGEAVQTCQAD-----RKWNGTQPVCVASSEYACGPPPTVSHAQFRITAES-------------HLLNVSYLCNAGMQLVGPETLTCLADGTWSLP-APTCEVARGCDGPVQLVHGRVQD 3199 HSP 7 Score: 85.5001 bits (210), Expect = 1.437e-16 Identity = 131/582 (22.51%), Postives = 206/582 (35.40%), Query Frame = 3
Query: 393 LQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCG-----------KLEDPKNGRTM----YNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEY------KCKSRSTLIGETSFLTCGEVDNKSGWLPKPEP-----------------------KCLLHCKP-FQVDSAKVYIHENNKTTN--------------------FIMHDEVTHGTHVRAKCNFGYELNSDILPAC-YNGSWNF-IPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTC 1937
++C P Q NG + L G Y+C G+ L+GP C AN P C + A + + D+S G + C G++ + H+ C W C CG ++ D + + + N+ + ++ C+ G++I T R CQ +G W+G C C PE+G V +V SI T+ C+ GY+L G +R+C W TC +C P I TTHG Y +C L G + + C +G P EP + L C P F + V++ + + T + M E + + V+ +C+ GY+L+ D C +G W+ +PRC +C P + + + S ++ + Y C GY I G L ++ G W E CQP C P G++ G + RL +++C Y+L GP A C G P +P C
Sbjct: 2347 IECPIPKQVANGKVAYRKLQFGHSATYSCHRGFRLEGPEMVKCLANGNWDLEPPNCVQISCTPPKAIENGFVEGQDHSF------GVTIFYSCFPGFQLVGQDHLT--CEEVGWSSSVPVCVPSDCGLPPHIDFGDYVRVTDSTSIDALTAAPLDLNFLHGTLIEYRCHKGYEITFHT--------RLMCQENGGWNGTAPSCIPAECETPPNPEHGWVNVTDASVGSIVTYSCERGYELKGESVRQCISGHLWTSDAPTCHPISCDNPGPI------DNGTTHGVDFVYLEVMHFECDPGFVLRGSDT-IACLADGKWNGQKPLCEPVLCGPPIVPSDVTVEGKEYTYNSRIELSCPPGFVLKGMSVHVCQADGTWSHESPTCIPARCSKPSPIPHGHYMGSEFGYNSKVKYECDRGYKLSGDPTLVCKSDGLWDKPVPRCDIISCDP-PEDISHGFLNGSSFNYNDVVEYVCFDGYEIV----GDPVLRCSYE-----GLWLGSVPE-CQPCVCALPGVKF-GKVLSSGHACGDRL-------------QFQCDKGYKLLGPSQATCEKGGVWSPGVPMC 2880 HSP 8 Score: 69.3218 bits (168), Expect = 1.235e-11 Identity = 46/134 (34.33%), Postives = 70/134 (52.24%), Query Frame = 3
Query: 954 CTAILCPELSPPENGE-VMGVWNT-VNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGP--PPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCL-LHCKPF 1340
C + CP LSPPENG V V N ++ +C+ G++L G+ +R C +G W G+ ++C VR+C P P F K T +GA+ + C L G ++ LTC S W +P+P+C+ + C P
Sbjct: 338 CQVVYCPALSPPENGFFVQNVCNNHFDAACGVRCQPGFELQGTGIRLCQADGTWSGTPASCRVRSCPPLSRPHHGFLKCGDGGTAYGAECQVGCARGYRLEGNST-LTC---QANSEW-SEPQPRCVEVRCSPI 466 HSP 9 Score: 58.5362 bits (140), Expect = 2.808e-8 Identity = 52/178 (29.21%), Postives = 73/178 (41.01%), Query Frame = 3
Query: 747 IKCEKKSCGKLEDPKNGRTMYN--NNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVM-GVWNTVNSIK-TFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTC 1268
+ C+ C L P+NG + N NN+ + ++ C GF++Q T R CQADG WSG A C CP LS P +G + G T + C GY+L G+ C W C+ C P IV K + + C ++ L G T L+C
Sbjct: 336 MTCQVVYCPALSPPENGFFVQNVCNNHFDAACGVR-CQPGFELQGTG--------IRLCQADGTWSGTPASCRVRSCPPLSRPHHGFLKCGDGGTAYGAECQVGCARGYRLEGNSTLTCQANSEWSEPQPRCVEVRCSP---IVNQK-------NFLLSPPACGKKAVLAGFTCILSC 494 HSP 10 Score: 58.151 bits (139), Expect = 3.216e-8 Identity = 65/293 (22.18%), Postives = 107/293 (36.52%), Query Frame = 3
Query: 399 CQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTD-LCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCE-KKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTF--------KCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIG 1247
C+ P ++G GD V Y+C G+ +KG + CQA+ + +G++P C ++ C P + + Q + +V +C G + + +G W CE + C +GR + + +++ Q C+ GF + D C WS C P+ PP G +V S + F C +G ++ GS C + W +S C CGPP + V G A Y C + T+ G
Sbjct: 3066 CEKPPPLLHGVIKGDSYNYGDLVLYSCLPGFDMKGEAVQTCQADRKWNGTQPVCVASSEYACGPPPTVSHAQFRITAESHLL----NVSYLCNAGMQLVGPETLTCLADGT-WSLPAPTCEVARGCDGPVQLVHGRVQDHILNSERALEFQ-CDKGFSL--VGDHL------VVCLGGNTWSSAFPTCQ----PKSCPPPPGWRGNSSRSVGSHQEFYVGQSVPVSCPKGQKVKGSGSITCRPDQTWTSVSSVCERVPCGPPLHVANGVVRGAVFQFGDVAVYSCYAGYTMEG 3340 HSP 11 Score: 52.373 bits (124), Expect = 1.877e-6 Identity = 43/175 (24.57%), Postives = 68/175 (38.86%), Query Frame = 3
Query: 663 IICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQF-CNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPE--------LSPPENGE--VMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPP 1154
+ CQ G+E + + +G W P C +SC L P +G + T Q C G++++ N CQA+ +WS C + C LSPP G+ V+ + + C++GY LHG+ C GNW + + + PP
Sbjct: 369 VRCQPGFELQGTGIRLCQADGT-WSGTPASCRVRSCPPLSRPHHGFLKCGDGGTAYGAECQVGCARGYRLE--------GNSTLTCQANSEWSEPQPRCVEVRCSPIVNQKNFLLSPPACGKKAVLAGFTCI-----LSCRKGYTLHGNRKAVCQSSGNWTANVHKAVCADTEPP 529
BLAST of C4b binding protein beta chain vs. Planmine SMEST
Match: SMESG000011729.1 (SMESG000011729.1) HSP 1 Score: 1104.74 bits (2856), Expect = 0.000e+0 Identity = 540/540 (100.00%), Postives = 540/540 (100.00%), Query Frame = 3
Query: 381 MEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQXXXXXXXXXXXNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYRSDDKK 2000
MEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQPKKCTKPPTPKNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYRSDDKK
Sbjct: 1 MEIDLQCQPPVQPVNGHANHSILLVGDQVEYTCKSGYALKGPRKRYCQANLRLSGSEPECTDQTDLCFSAPYIPYTQVHDNSNRDDFKNGEDVKIICQNGYEDPYKSHIIAKCNGNEWKYDPIKCEKKSCGKLEDPKNGRTMYNNNYTYQSIAIQFCNDGFKIQCTTDQFEDKNCRRQCQADGKWSGDTAICTAILCPELSPPENGEVMGVWNTVNSIKTFKCKEGYQLHGSHLRKCTREGNWDGSNSTCIVRNCGPPPEIVFAKVAYEATTHGAQAEYKCKSRSTLIGETSFLTCGEVDNKSGWLPKPEPKCLLHCKPFQVDSAKVYIHENNKTTNFIMHDEVTHGTHVRAKCNFGYELNSDILPACYNGSWNFIPRCVEAACSARPPSMKYSTVRFLSLKHDSLARYYCHFGYYIALRKDGMETLSTIFDIKCNKGNWTKMPTEGCQPKKCTKPPTPKNGEIYLLGQSDRTRLTDKSIKPIHNRVVKYECHPLYRLKGPKIAVCLNGHWSPPQMPTCEFIMHDELPISWLYYRSDDKK 540 The following BLAST results are available for this feature:
BLAST of C4b binding protein beta chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of C4b binding protein beta chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of C4b binding protein beta chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of C4b binding protein beta chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of C4b binding protein beta chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032384 ID=SMED30032384|Name=C4b binding protein beta chain|organism=Schmidtea mediterranea sexual|type=transcript|length=2054bpback to top protein sequence of SMED30032384-orf-1 >SMED30032384-orf-1 ID=SMED30032384-orf-1|Name=SMED30032384-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=646bp MKIFLQLIFTIVLIKNSLNELFPQNQNYKSRFHKIRHQRHLFLNLINPMKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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