Filamin A
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032338 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 164.081 bits (414), Expect = 1.490e-39 Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ VE D GN + + K+ S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + I + I SP+ + + ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482 HSP 2 Score: 90.8929 bits (224), Expect = 2.592e-17 Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V +DD R + + + N+ S +I+ G + V SP C V+E P K + GV+ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI + +L VTI+GPSKV++ C E GY Y P+ G Y I + Y HI GSPFK V Sbjct: 2183 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2460 HSP 3 Score: 83.9593 bits (206), Expect = 3.514e-15 Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD R CS+V++ + + + +S ++ +L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1813 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2078 HSP 4 Score: 82.8037 bits (203), Expect = 7.001e-15 Identity = 88/311 (28.30%), Postives = 128/311 (41.16%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK + ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V + V + N KP + F V EI V P G ++ I NKDG + V +A T +G++ + ++G I S PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVTEEAYVPV---SDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1900 HSP 5 Score: 72.7886 bits (177), Expect = 8.087e-12 Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + VK I + S+ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1984 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2275 HSP 6 Score: 71.2478 bits (173), Expect = 2.623e-11 Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P R+ V A D +R ++ ++ D+ E +S + VG + I H+++P + CFVT+ N DG Y +++ F L ++ D D+ I N + V E Q + A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ V Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415 HSP 7 Score: 70.0922 bits (170), Expect = 5.449e-11 Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +F P G + I I + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I Sbjct: 512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636 HSP 8 Score: 68.1662 bits (165), Expect = 2.473e-10 Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276 + I N PF+V V + + + GPGL + + P VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ + + V + KVK+ G+ + +SF +DS + P +V G+ +V + + P + V V Y ++ P+ + YD+++ S++ ++ +DA + L V + + K+ I+ H+ + + T+ I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ ++ T V + +P+ Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717 HSP 9 Score: 62.3882 bits (150), Expect = 1.295e-8 Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + F N N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420 HSP 10 Score: 62.003 bits (149), Expect = 1.652e-8 Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I ++ Sbjct: 1769 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1902 HSP 11 Score: 58.9214 bits (141), Expect = 1.570e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 56.9954 bits (136), Expect = 5.824e-7 Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I +SPY + ++ + D+ +++ V+ L+ K Sbjct: 2088 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2290 HSP 13 Score: 53.9138 bits (128), Expect = 5.132e-6 Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348 G +G +EGP E+++ C DG ++ P G Y++ +T G I GSPF + V + D P S V Q + +S K G P Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 164.081 bits (414), Expect = 1.708e-39 Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ VE D GN + + K+ S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + I + I SP+ + + ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482 HSP 2 Score: 90.8929 bits (224), Expect = 2.683e-17 Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V +DD R + + + N+ S +I+ G + V SP C V+E P K + GV+ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI + +L VTI+GPSKV++ C E GY Y P+ G Y I + Y HI GSPFK V Sbjct: 2194 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2471 HSP 3 Score: 83.9593 bits (206), Expect = 3.637e-15 Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD R CS+V++ + + + +S ++ +L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089 HSP 4 Score: 81.6481 bits (200), Expect = 1.722e-14 Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK + ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V +P + E + + N KP + F V EI V P G ++ I NKDG + V +A T +G++ + ++G I S PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911 HSP 5 Score: 72.7886 bits (177), Expect = 8.160e-12 Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + VK I + S+ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1995 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2286 HSP 6 Score: 71.2478 bits (173), Expect = 2.691e-11 Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P R+ V A D +R ++ ++ D+ E +S + VG + I H+++P + CFVT+ N DG Y +++ F L ++ D D+ I N + V E Q + A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ V Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415 HSP 7 Score: 70.0922 bits (170), Expect = 5.782e-11 Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +F P G + I I + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I Sbjct: 512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636 HSP 8 Score: 67.781 bits (164), Expect = 2.714e-10 Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276 + I N PF+V V + + + GPGL + + P VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ + + V + KVK+ G+ + +SF +DS + P +V G+ +V + + P + V V Y ++ P+ + YD+++ S++ ++ +DA + L V + + K+ I+ H+ + + T+ I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ ++ T V + +P+ Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717 HSP 9 Score: 62.3882 bits (150), Expect = 1.295e-8 Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + F N N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420 HSP 10 Score: 62.003 bits (149), Expect = 1.813e-8 Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I ++ Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1913 HSP 11 Score: 58.9214 bits (141), Expect = 1.571e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 56.6102 bits (135), Expect = 6.127e-7 Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I +SPY + ++ + D+ +++ V+ L+ K Sbjct: 2099 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2301 HSP 13 Score: 53.5286 bits (127), Expect = 5.265e-6 Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348 G +G +EGP E+++ C DG ++ P G Y++ +T G I GSPF + V + D P S V Q + +S K G P Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 164.081 bits (414), Expect = 1.775e-39 Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ VE D GN + + K+ S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + I + I SP+ + + ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482 HSP 2 Score: 90.8929 bits (224), Expect = 2.678e-17 Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V +DD R + + + N+ S +I+ G + V SP C V+E P K + GV+ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI + +L VTI+GPSKV++ C E GY Y P+ G Y I + Y HI GSPFK V Sbjct: 2170 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2447 HSP 3 Score: 83.9593 bits (206), Expect = 3.571e-15 Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD R CS+V++ + + + +S ++ +L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1800 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2065 HSP 4 Score: 81.6481 bits (200), Expect = 1.967e-14 Identity = 86/311 (27.65%), Postives = 127/311 (40.84%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK + ++AE ++ + G Y + Y PG YV + F VDIP+SPF + V ++ + + N KP + F V EI V P G ++ I NKDG + V +A T +G++ + ++G I S PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPV----------------SDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1887 HSP 5 Score: 72.7886 bits (177), Expect = 8.082e-12 Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + VK I + S+ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1971 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2262 HSP 6 Score: 71.2478 bits (173), Expect = 2.666e-11 Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P R+ V A D +R ++ ++ D+ E +S + VG + I H+++P + CFVT+ N DG Y +++ F L ++ D D+ I N + V E Q + A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ V Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415 HSP 7 Score: 70.0922 bits (170), Expect = 5.679e-11 Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +F P G + I I + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I Sbjct: 512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636 HSP 8 Score: 69.707 bits (169), Expect = 7.007e-11 Identity = 89/413 (21.55%), Postives = 165/413 (39.95%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243 + I N PF+V V + + + GPGL + + P VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ + + V + KVK+ G+ + +SF +DS + P +V G+ +V + + P + V V Y ++ P+ + YD+++ S++ ++ +DA + L V + + K+ I+ H+ + + T+ I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ V+E + Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEA 1708 HSP 9 Score: 62.3882 bits (150), Expect = 1.283e-8 Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + F N N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420 HSP 10 Score: 62.003 bits (149), Expect = 1.766e-8 Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I ++ Sbjct: 1756 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1889 HSP 11 Score: 58.5362 bits (140), Expect = 1.596e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 56.9954 bits (136), Expect = 5.970e-7 Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I +SPY + ++ + D+ +++ V+ L+ K Sbjct: 2075 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2277 HSP 13 Score: 53.9138 bits (128), Expect = 5.086e-6 Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348 G +G +EGP E+++ C DG ++ P G Y++ +T G I GSPF + V + D P S V Q + +S K G P Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 164.081 bits (414), Expect = 1.836e-39 Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ VE D GN + + K+ S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + I + I SP+ + + ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482 HSP 2 Score: 90.8929 bits (224), Expect = 2.711e-17 Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V +DD R + + + N+ S +I+ G + V SP C V+E P K + GV+ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI + +L VTI+GPSKV++ C E GY Y P+ G Y I + Y HI GSPFK V Sbjct: 2225 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2502 HSP 3 Score: 83.9593 bits (206), Expect = 3.644e-15 Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD R CS+V++ + + + +S ++ +L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1855 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2120 HSP 4 Score: 81.6481 bits (200), Expect = 1.725e-14 Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK + ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V +P + E + + N KP + F V EI V P G ++ I NKDG + V +A T +G++ + ++G I S PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1667 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1942 HSP 5 Score: 72.7886 bits (177), Expect = 8.173e-12 Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + VK I + S+ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 2026 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2317 HSP 6 Score: 71.2478 bits (173), Expect = 2.695e-11 Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P R+ V A D +R ++ ++ D+ E +S + VG + I H+++P + CFVT+ N DG Y +++ F L ++ D D+ I N + V E Q + A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ V Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415 HSP 7 Score: 70.0922 bits (170), Expect = 5.647e-11 Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +F P G + I I + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I Sbjct: 512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636 HSP 8 Score: 62.3882 bits (150), Expect = 1.297e-8 Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + F N N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420 HSP 9 Score: 62.003 bits (149), Expect = 1.484e-8 Identity = 42/143 (29.37%), Postives = 71/143 (49.65%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNS 1532 + I N PF+V V + + + GPGL + + P VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ + + V + KVK+ G+ + +SF +DS + Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKA 1450 HSP 10 Score: 61.6178 bits (148), Expect = 1.909e-8 Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I ++ Sbjct: 1811 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1944 HSP 11 Score: 58.5362 bits (140), Expect = 1.586e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 56.6102 bits (135), Expect = 6.506e-7 Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I +SPY + ++ + D+ +++ V+ L+ K Sbjct: 2130 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2332 HSP 13 Score: 53.9138 bits (128), Expect = 4.969e-6 Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348 G +G +EGP E+++ C DG ++ P G Y++ +T G I GSPF + V + D P S V Q + +S K G P Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454
BLAST of Filamin A vs. Ensembl Human
Match: FLNA (filamin A [Source:HGNC Symbol;Acc:HGNC:3754]) HSP 1 Score: 158.303 bits (399), Expect = 1.029e-37 Identity = 136/514 (26.46%), Postives = 232/514 (45.14%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-------QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S + NA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ Q +G + ++E G+ + +Y + G++ + + I SPY++ + ++ + V GL+ K + Sbjct: 23 TRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEAR--GDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGR-GLQPKGVR 496 HSP 2 Score: 106.301 bits (264), Expect = 5.238e-22 Identity = 100/326 (30.67%), Postives = 141/326 (43.25%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + GVY ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2231 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGVYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGNPAEFVVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508 HSP 3 Score: 79.7221 bits (195), Expect = 7.576e-14 Identity = 83/327 (25.38%), Postives = 141/327 (43.12%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + + T NKDG + V S G++ +D ++ +N+H + + L VD Y N + AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y N+ H+PGSPF V D + ++H Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPTITDNKDGTVTVRYAPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVD------------YVNCGHVTAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKY-NEQHVPGSPFTARVTGDDSMRMSH 1954 HSP 4 Score: 78.1814 bits (191), Expect = 1.894e-13 Identity = 99/456 (21.71%), Postives = 176/456 (38.60%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLI-IKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ +V ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + + + V R + +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VGPSGAAVPCKVEPGLGADNSV-VRFLPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPS----GNLTETYVQDRGDGMYKVEYTPYEEG----LHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.3218 bits (168), Expect = 1.017e-10 Identity = 39/98 (39.80%), Postives = 51/98 (52.04%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 V G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N+ +P SPF V D + R+ H V Sbjct: 1860 VTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKV 1957 HSP 6 Score: 69.3218 bits (168), Expect = 1.088e-10 Identity = 90/345 (26.09%), Postives = 145/345 (42.03%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ VG + + PE I ++ VT P G + H ++ + N I + +G + + S K K +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGTHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323 HSP 7 Score: 65.855 bits (159), Expect = 1.034e-9 Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNS 1532 F P++ G++ + I I PF V V + ++GPGL G V F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I + + +VK GLE F +D+++ Sbjct: 539 GFEYYPMVPGTYIVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHG 702 HSP 8 Score: 60.8474 bits (146), Expect = 3.215e-8 Identity = 35/132 (26.52%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N + +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + NE+++ SP++ + Sbjct: 1816 KDGTVTVRYAPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARV 1944 HSP 9 Score: 56.9954 bits (136), Expect = 4.809e-7 Identity = 58/218 (26.61%), Postives = 94/218 (43.12%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P F+++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK+ + P D G+ + V +K F ++C L+V V Sbjct: 2378 DKYAVRFIPRENGVYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVG--QKSSFTVDCSKAGNNMLLVGV 2586 HSP 10 Score: 54.299 bits (129), Expect = 3.184e-6 Identity = 67/295 (22.71%), Postives = 121/295 (41.02%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDG-RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIE-CPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEG 1739 I + + P V G DL +KIP I +++ + +G ++ +++ +P G+ + +K + PF+ V + + + GPGL + A P F I + ++EGPSK +I + +GS + Y PG Y++S+ NEE+I DSP+ +V V S D + ++ GL+ SF + + + D + G + VTE+++ + + P N LI V + + G P+ I + G Sbjct: 2136 ITRRRRAPSVANVGSHCDLSLKIPEIS---IQDMTAQVTSPSGKTHEAEIV--EGENHTYCIRFVPAEMGTHTVSVKYK--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPF-VVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAI--DAKVHSPSG-ALEECYVTEIDQDKYAVRFIPRENGVYLI-DVKFNGTHIPGSPFKIRVGEPGHG 2418
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 127.872 bits (320), Expect = 3.653e-29 Identity = 72/227 (31.72%), Postives = 120/227 (52.86%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSG 752 I++ FTRW+ + L+ + I L+ D +G L+ L ++LS K + +K+ F +Q ++ LN F E +++ NI+ I+D + K I L+W LI HYSI K G+N + + LNW+ ++L G I N +S WN G+A+G +VN+ D W+ ++AL N + AM++A + L+ P E+I + ++MTY+SQF Sbjct: 27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPA 250 HSP 2 Score: 73.9442 bits (180), Expect = 1.058e-12 Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3 Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568 P I ++G GL G + + P VF ++ NG + + F++EGPSK +I C +GS +++Y+ + G+Y++ ++ + ++I DSP+ + + + + + +V G++ + F +D+R ++ P VE D Sbjct: 543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682 HSP 3 Score: 52.373 bits (124), Expect = 4.404e-6 Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3 Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 D++ + + + F +EGP + ++ C + DG I+ + P AG Y++ V DGK I SPF + V+E Sbjct: 568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 128.257 bits (321), Expect = 4.564e-29 Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I++ FTRW+ + L+ + I L+ D +G L+ L ++LS K + +K+ F +Q ++ LN F E +++ NI+ I+D + K I L+W LI HYSI K G+N + + LNW+ ++L G I N +S WN G+A+G +VN+ D W+ ++AL N + AM++A + L+ P E+I + ++MTY+SQF Sbjct: 27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248 HSP 2 Score: 73.9442 bits (180), Expect = 1.280e-12 Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3 Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568 P I ++G GL G + + P VF ++ NG + + F++EGPSK +I C +GS +++Y+ + G+Y++ ++ + ++I DSP+ + + + + + +V G++ + F +D+R ++ P VE D Sbjct: 543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682 HSP 3 Score: 67.3958 bits (163), Expect = 1.305e-10 Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174 ++V G+ + +G N F ++ G +A+ IEGPSKA + F D G V Y+V PGEYV A+ FN IP SPF++ +A Sbjct: 1851 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1938 HSP 4 Score: 60.077 bits (144), Expect = 2.583e-8 Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 I A GDGL + T +K F I N I L V +DGPSK + E GY Y P+ G YF + Y N H PGSPFKI V Sbjct: 2044 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2127 HSP 5 Score: 59.6918 bits (143), Expect = 2.882e-8 Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3 Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 V G L V F V G L++ IEGP+K++I D K G ++ +PGEY + + SPFR+ V + +R H+ SEV + + KG S SIK SP + CFV GG SF P + T +DG + A + DK +G + KV++ G + TL NE+ + G G L V++ GPSK +++C E +G I Y P G+Y I I +++ H+ SP + Sbjct: 1481 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1742 HSP 6 Score: 55.4546 bits (132), Expect = 6.250e-7 Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201 KT+ GD S++ EV GKA KG N+ +V TS G L++ ++GPSKAE++ + K G+ V Y T PG Y AI F + SP + R++ Sbjct: 1651 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1754 HSP 7 Score: 53.9138 bits (128), Expect = 1.895e-6 Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171 I V + + + P+ + V GK LC KG +FV++T+ G L + ++GPSKA + + + G Y V Y PG Y ++ +N + P SPF+I V Sbjct: 2015 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2127 HSP 8 Score: 53.5286 bits (127), Expect = 2.150e-6 Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3 Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547 +YGPGL +V VF LD +G+ + + M GP+K + + GNG + Y A PG Y+++I +E++ SP+ V+ + + ++ + GL+ N + +F+ID+ + T ++P Sbjct: 931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055 HSP 9 Score: 52.7582 bits (125), Expect = 4.073e-6 Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439 P + GS ++ I +N ++ P + V+ V YGPGL +V P F + GS +++ S+EGP+K++I+ + +G+ + +PG Y++ + + + + DSP+ ++++ Sbjct: 1445 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1564 HSP 10 Score: 51.9878 bits (123), Expect = 6.521e-6 Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3 Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 D++ + + + F +EGP + ++ C + DG I+ + P AG Y++ V DGK I SPF + V+E Sbjct: 568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 128.257 bits (321), Expect = 4.842e-29 Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I++ FTRW+ + L+ + I L+ D +G L+ L ++LS K + +K+ F +Q ++ LN F E +++ NI+ I+D + K I L+W LI HYSI K G+N + + LNW+ ++L G I N +S WN G+A+G +VN+ D W+ ++AL N + AM++A + L+ P E+I + ++MTY+SQF Sbjct: 27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248 HSP 2 Score: 73.9442 bits (180), Expect = 1.324e-12 Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3 Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568 P I ++G GL G + + P VF ++ NG + + F++EGPSK +I C +GS +++Y+ + G+Y++ ++ + ++I DSP+ + + + + + +V G++ + F +D+R ++ P VE D Sbjct: 543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682 HSP 3 Score: 67.3958 bits (163), Expect = 1.305e-10 Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174 ++V G+ + +G N F ++ G +A+ IEGPSKA + F D G V Y+V PGEYV A+ FN IP SPF++ +A Sbjct: 1853 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1940 HSP 4 Score: 60.077 bits (144), Expect = 2.562e-8 Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 I A GDGL + T +K F I N I L V +DGPSK + E GY Y P+ G YF + Y N H PGSPFKI V Sbjct: 2046 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2129 HSP 5 Score: 59.6918 bits (143), Expect = 2.882e-8 Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3 Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 V G L V F V G L++ IEGP+K++I D K G ++ +PGEY + + SPFR+ V + +R H+ SEV + + KG S SIK SP + CFV GG SF P + T +DG + A + DK +G + KV++ G + TL NE+ + G G L V++ GPSK +++C E +G I Y P G+Y I I +++ H+ SP + Sbjct: 1483 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1744 HSP 6 Score: 55.4546 bits (132), Expect = 6.250e-7 Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201 KT+ GD S++ EV GKA KG N+ +V TS G L++ ++GPSKAE++ + K G+ V Y T PG Y AI F + SP + R++ Sbjct: 1653 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1756 HSP 7 Score: 53.9138 bits (128), Expect = 1.896e-6 Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171 I V + + + P+ + V GK LC KG +FV++T+ G L + ++GPSKA + + + G Y V Y PG Y ++ +N + P SPF+I V Sbjct: 2017 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2129 HSP 8 Score: 53.5286 bits (127), Expect = 2.205e-6 Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3 Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547 +YGPGL +V VF LD +G+ + + M GP+K + + GNG + Y A PG Y+++I +E++ SP+ V+ + + ++ + GL+ N + +F+ID+ + T ++P Sbjct: 931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055 HSP 9 Score: 52.7582 bits (125), Expect = 4.039e-6 Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439 P + GS ++ I +N ++ P + V+ V YGPGL +V P F + GS +++ S+EGP+K++I+ + +G+ + +PG Y++ + + + + DSP+ ++++ Sbjct: 1447 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1566 HSP 10 Score: 51.9878 bits (123), Expect = 6.688e-6 Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3 Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 D++ + + + F +EGP + ++ C + DG I+ + P AG Y++ V DGK I SPF + V+E Sbjct: 568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 127.872 bits (320), Expect = 5.313e-29 Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I++ FTRW+ + L+ + I L+ D +G L+ L ++LS K + +K+ F +Q ++ LN F E +++ NI+ I+D + K I L+W LI HYSI K G+N + + LNW+ ++L G I N +S WN G+A+G +VN+ D W+ ++AL N + AM++A + L+ P E+I + ++MTY+SQF Sbjct: 27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248 HSP 2 Score: 74.3294 bits (181), Expect = 1.133e-12 Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3 Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568 P I ++G GL G + + P VF ++ NG + + F++EGPSK +I C +GS +++Y+ + G+Y++ ++ + ++I DSP+ + + + + + +V G++ + F +D+R ++ P VE D Sbjct: 543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682 HSP 3 Score: 67.3958 bits (163), Expect = 1.258e-10 Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174 ++V G+ + +G N F ++ G +A+ IEGPSKA + F D G V Y+V PGEYV A+ FN IP SPF++ +A Sbjct: 1800 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1887 HSP 4 Score: 60.077 bits (144), Expect = 2.512e-8 Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 I A GDGL + T +K F I N I L V +DGPSK + E GY Y P+ G YF + Y N H PGSPFKI V Sbjct: 1993 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2076 HSP 5 Score: 59.6918 bits (143), Expect = 2.710e-8 Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3 Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 V G L V F V G L++ IEGP+K++I D K G ++ +PGEY + + SPFR+ V + +R H+ SEV + + KG S SIK SP + CFV GG SF P + T +DG + A + DK +G + KV++ G + TL NE+ + G G L V++ GPSK +++C E +G I Y P G+Y I I +++ H+ SP + Sbjct: 1430 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1691 HSP 6 Score: 55.4546 bits (132), Expect = 6.028e-7 Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201 KT+ GD S++ EV GKA KG N+ +V TS G L++ ++GPSKAE++ + K G+ V Y T PG Y AI F + SP + R++ Sbjct: 1600 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1703 HSP 7 Score: 53.9138 bits (128), Expect = 1.768e-6 Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171 I V + + + P+ + V GK LC KG +FV++T+ G L + ++GPSKA + + + G Y V Y PG Y ++ +N + P SPF+I V Sbjct: 1964 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2076 HSP 8 Score: 53.5286 bits (127), Expect = 2.200e-6 Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3 Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547 +YGPGL +V VF LD +G+ + + M GP+K + + GNG + Y A PG Y+++I +E++ SP+ V+ + + ++ + GL+ N + +F+ID+ + T ++P Sbjct: 931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055 HSP 9 Score: 52.7582 bits (125), Expect = 4.029e-6 Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439 P + GS ++ I +N ++ P + V+ V YGPGL +V P F + GS +++ S+EGP+K++I+ + +G+ + +PG Y++ + + + + DSP+ ++++ Sbjct: 1394 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1513 HSP 10 Score: 51.9878 bits (123), Expect = 6.617e-6 Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3 Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 D++ + + + F +EGP + ++ C + DG I+ + P AG Y++ V DGK I SPF + V+E Sbjct: 568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 127.872 bits (320), Expect = 5.497e-29 Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I++ FTRW+ + L+ + I L+ D +G L+ L ++LS K + +K+ F +Q ++ LN F E +++ NI+ I+D + K I L+W LI HYSI K G+N + + LNW+ ++L G I N +S WN G+A+G +VN+ D W+ ++AL N + AM++A + L+ P E+I + ++MTY+SQF Sbjct: 27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248 HSP 2 Score: 74.3294 bits (181), Expect = 1.134e-12 Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3 Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568 P I ++G GL G + + P VF ++ NG + + F++EGPSK +I C +GS +++Y+ + G+Y++ ++ + ++I DSP+ + + + + + +V G++ + F +D+R ++ P VE D Sbjct: 543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682 HSP 3 Score: 67.3958 bits (163), Expect = 1.268e-10 Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174 ++V G+ + +G N F ++ G +A+ IEGPSKA + F D G V Y+V PGEYV A+ FN IP SPF++ +A Sbjct: 1802 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1889 HSP 4 Score: 60.077 bits (144), Expect = 2.512e-8 Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 I A GDGL + T +K F I N I L V +DGPSK + E GY Y P+ G YF + Y N H PGSPFKI V Sbjct: 1995 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2078 HSP 5 Score: 59.6918 bits (143), Expect = 2.733e-8 Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3 Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 V G L V F V G L++ IEGP+K++I D K G ++ +PGEY + + SPFR+ V + +R H+ SEV + + KG S SIK SP + CFV GG SF P + T +DG + A + DK +G + KV++ G + TL NE+ + G G L V++ GPSK +++C E +G I Y P G+Y I I +++ H+ SP + Sbjct: 1432 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1693 HSP 6 Score: 55.4546 bits (132), Expect = 6.028e-7 Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201 KT+ GD S++ EV GKA KG N+ +V TS G L++ ++GPSKAE++ + K G+ V Y T PG Y AI F + SP + R++ Sbjct: 1602 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1705 HSP 7 Score: 53.9138 bits (128), Expect = 1.768e-6 Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171 I V + + + P+ + V GK LC KG +FV++T+ G L + ++GPSKA + + + G Y V Y PG Y ++ +N + P SPF+I V Sbjct: 1966 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2078 HSP 8 Score: 53.5286 bits (127), Expect = 2.200e-6 Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3 Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547 +YGPGL +V VF LD +G+ + + M GP+K + + GNG + Y A PG Y+++I +E++ SP+ V+ + + ++ + GL+ N + +F+ID+ + T ++P Sbjct: 931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055 HSP 9 Score: 52.7582 bits (125), Expect = 3.996e-6 Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439 P + GS ++ I +N ++ P + V+ V YGPGL +V P F + GS +++ S+EGP+K++I+ + +G+ + +PG Y++ + + + + DSP+ ++++ Sbjct: 1396 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1515 HSP 10 Score: 51.9878 bits (123), Expect = 6.562e-6 Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3 Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 D++ + + + F +EGP + ++ C + DG I+ + P AG Y++ V DGK I SPF + V+E Sbjct: 568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0089471) HSP 1 Score: 154.451 bits (389), Expect = 5.877e-37 Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3 Query: 63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 E +R +E + KI++ FTRW N LK ++ I +L+ DL +G L+ LIE+LSQK++ K R ++ ++ L FL+ EG+++ NI+ DI+D +K I L+W LI HYSI + GE++ G + LNW+++K+ I+N ++ W +G A+G +V+ C LC D W+ +A+ NA AM A + QL+KP E+++ + ++++MTY+SQ+ + L + N N+ G + + G A + + S G VD+ I+ P NG + K N K+ + S IP GS + +K + +I PF V V + V GPG+ + D D G + P+ K A + N + Y L G++ +++ I +SP+ VK + + +KV+ G + T + D + E P+V G+ + N++ ++++ + R ++ V + +V P+ + Sbjct: 2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542 HSP 2 Score: 112.464 bits (280), Expect = 4.022e-24 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 G L +G V +F V T G+LAI +EGPSKA+I F D+K G VSY+VT PGEY + FN IP SPF++ V+ D HK EV+ +GN + P + + + E L+ + P G ++ D FI V + Y++ FY + + VK +H + + V + +P V+ A G+GL + K F I N +L V+IDGPSKV + C E GY Y P++ G ++I + Y+N HI GSPFK+ D +D QE Sbjct: 1811 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2091 HSP 3 Score: 91.6633 bits (226), Expect = 6.965e-18 Identity = 113/469 (24.09%), Postives = 190/469 (40.51%), Query Frame = 3 Query: 972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTK--KLIIKHETFEESQLKT----FKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246 +N++ VD GN Y+C ++ + E + ++ +G E+ PF V V P K+ +IV+YGPGL V P F+++TNG +GF++ GPS+ +IEC + G+GS L+ Y G Y + I+ + E+I SP+ + ++ +++ E+ K GLE SF +D + P DV D G NN T+ +E Y + P N+ R+ V V +V+ F P A +D ++ + + KV + ++ C I N+D ++E+ T R + ++ +T + S++K I + S G I G+ D +G VL I VQ D + I + P AG++ + + D + GSPF + V D Sbjct: 500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGEKVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD--------PMGHVLPSKI---VQ--GPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCD 934 HSP 4 Score: 79.7221 bits (195), Expect = 2.857e-14 Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G F + T G G L + +EGPSKA+I++ D K G V Y T PGEY ++ F I SP+ + + +R + CSEV M ++ + + + +P L CF+ P G G SF P +K++ K N F ++G + KVK+ G GL++ + N F + N L V+I+GPSK +I C + +G + Y P G Y + + +++ H+ GSPF + V Sbjct: 1431 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1698 HSP 5 Score: 73.9442 bits (180), Expect = 1.883e-12 Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +V V G L +G + +N F V T G L++ IEGPSKAEI DK G +SY+ T PG Y+ + F + SPF + VA + + R K +Q + ++ I +G L F + +L VT P + I+++ +DG ++ +GV+ + S + +I GS T + PL + + A G GL++ V F + W SL ++++GPSK I + +G Y G Y +G+ ++++ HIP SPFK+ V D Sbjct: 1613 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 1894 HSP 6 Score: 70.8626 bits (172), Expect = 1.382e-11 Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P G L KG N NKF V T G G L++ IEGPS+A+++ D + G V Y T PGEY I F IP SPFR+ V + V+ Sbjct: 935 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1027 HSP 7 Score: 57.3806 bits (137), Expect = 1.671e-7 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 N+ E +G V K N + +S P GS ++ +K N + PF+ V+ + +YGPGL V P F + T G S + ++EGPSK I + +G+V + Y PG YQ+S+ +++I SPY Sbjct: 1366 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1511 HSP 8 Score: 55.0694 bits (131), Expect = 8.463e-7 Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 I V ++++ P+EV V G L G + + FVV T+G+ G L + GPS+AEI D G +V Y T GEY I + DIP SPF Sbjct: 526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631 HSP 9 Score: 53.1434 bits (126), Expect = 3.779e-6 Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PF V V +YGPGL + + F ++T G+ + + ++EGPS+ K+ C + +GS + Y A PG Y ++I +++I SP+ +++ ++ VD KVKV G Sbjct: 918 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1035
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337101) HSP 1 Score: 154.451 bits (389), Expect = 7.308e-37 Identity = 143/585 (24.44%), Postives = 254/585 (43.42%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 ++ E +R +E + KI++ FTRW N LK ++ I +L+ DL +G L+ LIE+LSQK++ K R ++ ++ L FL+ EG+++ NI+ DI+D +K I L+W LI HYSI + GE++ G + LNW+++K+ I+N ++ W +G A+G +V+ C LC D W+ +A+ NA AM A + QL+KP E+++ + ++++MTY+SQ+ + L + N N+ G + + G A + + S G VD+ I+ P NG + K N K+ + S IP GS + +K + +I PF V V + V GPG+ + D D G + P+ K A + N + Y L G++ +++ I +SP+ VK + + +KV+ G + T + D + E P+V G+ + N++ ++++ + R ++ V + +V P+ + Sbjct: 28 DEDMEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 572 HSP 2 Score: 112.849 bits (281), Expect = 3.127e-24 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 G L +G V +F V T G+LAI +EGPSKA+I F D+K G VSY+VT PGEY + FN IP SPF++ V+ D HK EV+ +GN + P + + + E L+ + P G ++ D FI V + Y++ FY + + VK +H + + V + +P V+ A G+GL + K F I N +L V+IDGPSKV + C E GY Y P++ G ++I + Y+N HI GSPFK+ D +D QE Sbjct: 2030 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2310 HSP 3 Score: 90.5077 bits (223), Expect = 1.837e-17 Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3 Query: 972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832 +N++ VD GN Y+C ++ + E + ++ +G E+ PF V V P K+ +IV+YGPGL V P F+++TNG +GF++ GPS+ +IEC + G+GS L+ Y G Y + I+ + E+I SP+ + ++ +++ E+ K GLE SF +D + P DV D G NN T+ +E Y + P N+ R+ V V +V+ F P A +D ++ + + KV + ++ C I N+D ++E+ Sbjct: 530 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 833 HSP 4 Score: 80.1073 bits (196), Expect = 2.238e-14 Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G F + T G G L + +EGPSKA+I++ D K G V Y T PGEY ++ F I SP+ + + +R + CSEV M ++ + + + +P L CF+ P G G SF P +K++ K N F ++G + KVK+ G GL++ + N F + N L V+I+GPSK +I C + +G + Y P G Y + + +++ H+ GSPF + V Sbjct: 1650 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1917 HSP 5 Score: 74.3294 bits (181), Expect = 1.588e-12 Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +V V G L +G + +N F V T G L++ IEGPSKAEI DK G +SY+ T PG Y+ + F + SPF + VA + + R K +Q + ++ I +G L F + +L VT P + I+++ +DG ++ +GV+ + S + +I GS T + PL + + A G GL++ V F + W SL ++++GPSK I + +G Y G Y +G+ ++++ HIP SPFK+ V D Sbjct: 1832 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2113 HSP 6 Score: 71.2478 bits (173), Expect = 1.267e-11 Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P G L KG N NKF V T G G L++ IEGPS+A+++ D + G V Y T PGEY I F IP SPFR+ V + V+ Sbjct: 1154 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1246 HSP 7 Score: 65.0846 bits (157), Expect = 7.987e-10 Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718 I +PFR+ + + ++GPGL + P F++DT G+ Q +G ++EGP + I C + G+G+ + Y G Y ++I NE +I SP+ +IV V +K +V IG++ F++D S+ + + C FD +G + +V FRI A R + + Y + V G P+ ++ Sbjct: 944 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1147 HSP 8 Score: 57.3806 bits (137), Expect = 2.136e-7 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 N+ E +G V K N + +S P GS ++ +K N + PF+ V+ + +YGPGL V P F + T G S + ++EGPSK I + +G+V + Y PG YQ+S+ +++I SPY Sbjct: 1585 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1730 HSP 9 Score: 55.4546 bits (132), Expect = 7.992e-7 Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 I V ++++ P+EV V G L G + + FVV T+G+ G L + GPS+AEI D G +V Y T GEY I + DIP SPF Sbjct: 556 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 661 HSP 10 Score: 52.7582 bits (125), Expect = 4.291e-6 Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PF V V +YGPGL + + F ++T G+ + + ++EGPS+ K+ C + +GS + Y A PG Y ++I +++I SP+ +++ ++ VD KVKV G Sbjct: 1137 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1254 HSP 11 Score: 51.6026 bits (122), Expect = 9.943e-6 Identity = 33/104 (31.73%), Postives = 52/104 (50.00%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFR---ITVADDVNRRILHKHVKP 5216 +V G L +G V +F++ T G G L + +EGP +A I+ D G V+Y T G+Y I+FN+ I SPF+ + V + N R+ ++P Sbjct: 961 KVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPVPNLKNTRVSGIGIQP 1064
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0303364) HSP 1 Score: 154.066 bits (388), Expect = 8.641e-37 Identity = 143/585 (24.44%), Postives = 254/585 (43.42%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 ++ E +R +E + KI++ FTRW N LK ++ I +L+ DL +G L+ LIE+LSQK++ K R ++ ++ L FL+ EG+++ NI+ DI+D +K I L+W LI HYSI + GE++ G + LNW+++K+ I+N ++ W +G A+G +V+ C LC D W+ +A+ NA AM A + QL+KP E+++ + ++++MTY+SQ+ + L + N N+ G + + G A + + S G VD+ I+ P NG + K N K+ + S IP GS + +K + +I PF V V + V GPG+ + D D G + P+ K A + N + Y L G++ +++ I +SP+ VK + + +KV+ G + T + D + E P+V G+ + N++ ++++ + R ++ V + +V P+ + Sbjct: 28 DEDMEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 572 HSP 2 Score: 112.464 bits (280), Expect = 3.839e-24 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 G L +G V +F V T G+LAI +EGPSKA+I F D+K G VSY+VT PGEY + FN IP SPF++ V+ D HK EV+ +GN + P + + + E L+ + P G ++ D FI V + Y++ FY + + VK +H + + V + +P V+ A G+GL + K F I N +L V+IDGPSKV + C E GY Y P++ G ++I + Y+N HI GSPFK+ D +D QE Sbjct: 1841 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2121 HSP 3 Score: 91.2781 bits (225), Expect = 1.073e-17 Identity = 113/469 (24.09%), Postives = 190/469 (40.51%), Query Frame = 3 Query: 972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTK--KLIIKHETFEESQLKT----FKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246 +N++ VD GN Y+C ++ + E + ++ +G E+ PF V V P K+ +IV+YGPGL V P F+++TNG +GF++ GPS+ +IEC + G+GS L+ Y G Y + I+ + E+I SP+ + ++ +++ E+ K GLE SF +D + P DV D G NN T+ +E Y + P N+ R+ V V +V+ F P A +D ++ + + KV + ++ C I N+D ++E+ T R + ++ +T + S++K I + S G I G+ D +G VL I VQ D + I + P AG++ + + D + GSPF + V D Sbjct: 530 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGEKVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD--------PMGHVLPSKI---VQ--GPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCD 964 HSP 4 Score: 79.7221 bits (195), Expect = 2.817e-14 Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G F + T G G L + +EGPSKA+I++ D K G V Y T PGEY ++ F I SP+ + + +R + CSEV M ++ + + + +P L CF+ P G G SF P +K++ K N F ++G + KVK+ G GL++ + N F + N L V+I+GPSK +I C + +G + Y P G Y + + +++ H+ GSPF + V Sbjct: 1461 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1728 HSP 5 Score: 73.9442 bits (180), Expect = 1.825e-12 Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +V V G L +G + +N F V T G L++ IEGPSKAEI DK G +SY+ T PG Y+ + F + SPF + VA + + R K +Q + ++ I +G L F + +L VT P + I+++ +DG ++ +GV+ + S + +I GS T + PL + + A G GL++ V F + W SL ++++GPSK I + +G Y G Y +G+ ++++ HIP SPFK+ V D Sbjct: 1643 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 1924 HSP 6 Score: 70.8626 bits (172), Expect = 1.373e-11 Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P G L KG N NKF V T G G L++ IEGPS+A+++ D + G V Y T PGEY I F IP SPFR+ V + V+ Sbjct: 965 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1057 HSP 7 Score: 57.3806 bits (137), Expect = 1.760e-7 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 N+ E +G V K N + +S P GS ++ +K N + PF+ V+ + +YGPGL V P F + T G S + ++EGPSK I + +G+V + Y PG YQ+S+ +++I SPY Sbjct: 1396 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1541 HSP 8 Score: 55.4546 bits (132), Expect = 8.335e-7 Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 I V ++++ P+EV V G L G + + FVV T+G+ G L + GPS+AEI D G +V Y T GEY I + DIP SPF Sbjct: 556 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 661 HSP 9 Score: 53.1434 bits (126), Expect = 3.914e-6 Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PF V V +YGPGL + + F ++T G+ + + ++EGPS+ K+ C + +GS + Y A PG Y ++I +++I SP+ +++ ++ VD KVKV G Sbjct: 948 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1065
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0290014) HSP 1 Score: 153.68 bits (387), Expect = 1.156e-36 Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3 Query: 63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 E +R +E + KI++ FTRW N LK ++ I +L+ DL +G L+ LIE+LSQK++ K R ++ ++ L FL+ EG+++ NI+ DI+D +K I L+W LI HYSI + GE++ G + LNW+++K+ I+N ++ W +G A+G +V+ C LC D W+ +A+ NA AM A + QL+KP E+++ + ++++MTY+SQ+ + L + N N+ G + + G A + + S G VD+ I+ P NG + K N K+ + S IP GS + +K + +I PF V V + V GPG+ + D D G + P+ K A + N + Y L G++ +++ I +SP+ VK + + +KV+ G + T + D + E P+V G+ + N++ ++++ + R ++ V + +V P+ + Sbjct: 2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542 HSP 2 Score: 112.849 bits (281), Expect = 3.143e-24 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 G L +G V +F V T G+LAI +EGPSKA+I F D+K G VSY+VT PGEY + FN IP SPF++ V+ D HK EV+ +GN + P + + + E L+ + P G ++ D FI V + Y++ FY + + VK +H + + V + +P V+ A G+GL + K F I N +L V+IDGPSKV + C E GY Y P++ G ++I + Y+N HI GSPFK+ D +D QE Sbjct: 2000 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2280 HSP 3 Score: 90.1225 bits (222), Expect = 2.339e-17 Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3 Query: 972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832 +N++ VD GN Y+C ++ + E + ++ +G E+ PF V V P K+ +IV+YGPGL V P F+++TNG +GF++ GPS+ +IEC + G+GS L+ Y G Y + I+ + E+I SP+ + ++ +++ E+ K GLE SF +D + P DV D G NN T+ +E Y + P N+ R+ V V +V+ F P A +D ++ + + KV + ++ C I N+D ++E+ Sbjct: 500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 803 HSP 4 Score: 80.1073 bits (196), Expect = 2.290e-14 Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G F + T G G L + +EGPSKA+I++ D K G V Y T PGEY ++ F I SP+ + + +R + CSEV M ++ + + + +P L CF+ P G G SF P +K++ K N F ++G + KVK+ G GL++ + N F + N L V+I+GPSK +I C + +G + Y P G Y + + +++ H+ GSPF + V Sbjct: 1620 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1887 HSP 5 Score: 74.3294 bits (181), Expect = 1.559e-12 Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +V V G L +G + +N F V T G L++ IEGPSKAEI DK G +SY+ T PG Y+ + F + SPF + VA + + R K +Q + ++ I +G L F + +L VT P + I+++ +DG ++ +GV+ + S + +I GS T + PL + + A G GL++ V F + W SL ++++GPSK I + +G Y G Y +G+ ++++ HIP SPFK+ V D Sbjct: 1802 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2083 HSP 6 Score: 71.2478 bits (173), Expect = 1.265e-11 Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P G L KG N NKF V T G G L++ IEGPS+A+++ D + G V Y T PGEY I F IP SPFR+ V + V+ Sbjct: 1124 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1216 HSP 7 Score: 65.0846 bits (157), Expect = 1.001e-9 Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718 I +PFR+ + + ++GPGL + P F++DT G+ Q +G ++EGP + I C + G+G+ + Y G Y ++I NE +I SP+ +IV V +K +V IG++ F++D S+ + + C FD +G + +V FRI A R + + Y + V G P+ ++ Sbjct: 914 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1117 HSP 8 Score: 56.9954 bits (136), Expect = 2.588e-7 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 N+ E +G V K N + +S P GS ++ +K N + PF+ V+ + +YGPGL V P F + T G S + ++EGPSK I + +G+V + Y PG YQ+S+ +++I SPY Sbjct: 1555 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1700 HSP 9 Score: 55.4546 bits (132), Expect = 7.982e-7 Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 I V ++++ P+EV V G L G + + FVV T+G+ G L + GPS+AEI D G +V Y T GEY I + DIP SPF Sbjct: 526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631 HSP 10 Score: 52.7582 bits (125), Expect = 5.333e-6 Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PF V V +YGPGL + + F ++T G+ + + ++EGPS+ K+ C + +GS + Y A PG Y ++I +++I SP+ +++ ++ VD KVKV G Sbjct: 1107 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1224
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337100) HSP 1 Score: 153.68 bits (387), Expect = 1.156e-36 Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3 Query: 63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 E +R +E + KI++ FTRW N LK ++ I +L+ DL +G L+ LIE+LSQK++ K R ++ ++ L FL+ EG+++ NI+ DI+D +K I L+W LI HYSI + GE++ G + LNW+++K+ I+N ++ W +G A+G +V+ C LC D W+ +A+ NA AM A + QL+KP E+++ + ++++MTY+SQ+ + L + N N+ G + + G A + + S G VD+ I+ P NG + K N K+ + S IP GS + +K + +I PF V V + V GPG+ + D D G + P+ K A + N + Y L G++ +++ I +SP+ VK + + +KV+ G + T + D + E P+V G+ + N++ ++++ + R ++ V + +V P+ + Sbjct: 2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542 HSP 2 Score: 112.849 bits (281), Expect = 3.143e-24 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 G L +G V +F V T G+LAI +EGPSKA+I F D+K G VSY+VT PGEY + FN IP SPF++ V+ D HK EV+ +GN + P + + + E L+ + P G ++ D FI V + Y++ FY + + VK +H + + V + +P V+ A G+GL + K F I N +L V+IDGPSKV + C E GY Y P++ G ++I + Y+N HI GSPFK+ D +D QE Sbjct: 2000 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2280 HSP 3 Score: 90.1225 bits (222), Expect = 2.339e-17 Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3 Query: 972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832 +N++ VD GN Y+C ++ + E + ++ +G E+ PF V V P K+ +IV+YGPGL V P F+++TNG +GF++ GPS+ +IEC + G+GS L+ Y G Y + I+ + E+I SP+ + ++ +++ E+ K GLE SF +D + P DV D G NN T+ +E Y + P N+ R+ V V +V+ F P A +D ++ + + KV + ++ C I N+D ++E+ Sbjct: 500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 803 HSP 4 Score: 80.1073 bits (196), Expect = 2.290e-14 Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G F + T G G L + +EGPSKA+I++ D K G V Y T PGEY ++ F I SP+ + + +R + CSEV M ++ + + + +P L CF+ P G G SF P +K++ K N F ++G + KVK+ G GL++ + N F + N L V+I+GPSK +I C + +G + Y P G Y + + +++ H+ GSPF + V Sbjct: 1620 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1887 HSP 5 Score: 74.3294 bits (181), Expect = 1.559e-12 Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +V V G L +G + +N F V T G L++ IEGPSKAEI DK G +SY+ T PG Y+ + F + SPF + VA + + R K +Q + ++ I +G L F + +L VT P + I+++ +DG ++ +GV+ + S + +I GS T + PL + + A G GL++ V F + W SL ++++GPSK I + +G Y G Y +G+ ++++ HIP SPFK+ V D Sbjct: 1802 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2083 HSP 6 Score: 71.2478 bits (173), Expect = 1.265e-11 Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P G L KG N NKF V T G G L++ IEGPS+A+++ D + G V Y T PGEY I F IP SPFR+ V + V+ Sbjct: 1124 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1216 HSP 7 Score: 65.0846 bits (157), Expect = 1.001e-9 Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718 I +PFR+ + + ++GPGL + P F++DT G+ Q +G ++EGP + I C + G+G+ + Y G Y ++I NE +I SP+ +IV V +K +V IG++ F++D S+ + + C FD +G + +V FRI A R + + Y + V G P+ ++ Sbjct: 914 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1117 HSP 8 Score: 56.9954 bits (136), Expect = 2.588e-7 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 N+ E +G V K N + +S P GS ++ +K N + PF+ V+ + +YGPGL V P F + T G S + ++EGPSK I + +G+V + Y PG YQ+S+ +++I SPY Sbjct: 1555 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1700 HSP 9 Score: 55.4546 bits (132), Expect = 7.982e-7 Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 I V ++++ P+EV V G L G + + FVV T+G+ G L + GPS+AEI D G +V Y T GEY I + DIP SPF Sbjct: 526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631 HSP 10 Score: 52.7582 bits (125), Expect = 5.333e-6 Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PF V V +YGPGL + + F ++T G+ + + ++EGPS+ K+ C + +GS + Y A PG Y ++I +++I SP+ +++ ++ VD KVKV G Sbjct: 1107 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1224
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flnb (filamin B, beta (actin binding protein 278) [Source:ZFIN;Acc:ZDB-GENE-041026-1]) HSP 1 Score: 194.126 bits (492), Expect = 6.474e-49 Identity = 152/559 (27.19%), Postives = 247/559 (44.19%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNF-DEIGK-----SFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715 KI+K FTRW N L+ N I DL+ DL +G +L+ L+E+LS K++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI T + E+ D + K L W+ +K+ I N S W G A+G +V+ LC D W+S + ++N + AM+ A +PQL+ P EI+D + ++++MTY+S F + + G + I + ++++ + D + G NL V D +G+ T+ F F P G + I I PF+V V I +GPGL G P F++++ G+D +GF++EGPS+ KI C + +GS + + G Y + +M ++E I DSP+ I +K KVKV G T FI+D+R + F D EC D + ++ + F ++ + + V + V V G P+ + Sbjct: 23 KIQKNTFTRWCNEHLRSVNMRISDLKTDLSDGLVLISLLEVLSHKRMFRKYHTRPTFRQLKLDNVSVALEFLDHEKVKLVSIDSKAIVDGNLKLILGLVWTLIQHYSISTPVWEDEANDSVSKLTPEMRLLGWIQNKVPELPITNFSQDWQDGKALGALVDGLAPGLCPDWESWDSVHRVSNTKEAMQQADDWLGVPQLIAPEEILDPAVDEQSVMTYLSLFPKARLKPGAPLKPKKVPKPKACRATG--RGLQSKGIRVEQLAEFKV-------DTCRAG---------------PGNLDVHIRDPSGSEVSVTQKELF--KGVFGFQYTPSAEGDHTVDI--TWVGQHISKSPFKVNVGPEAGPQKIRVWGPGLEGGTVGSPAQFMVESVGADSGMLGFAIEGPSQAKIACDDHNDGSCQVRFWPTEAGEYAVHVMCDDEEIQDSPFMASIRPKSKGFHPDKVKVEGPGVSQTGCVINLQNEFIVDTRQAGEGELAVFAQRADGECVD--------VTISSEQSGVFVCSYTPSSLSKHTIAVTWGGVMVPGSPFIV 545 HSP 2 Score: 78.1814 bits (191), Expect = 1.183e-13 Identity = 92/334 (27.54%), Postives = 138/334 (41.32%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTS---------NKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +V+ G L +G V +F++ TS G L + ++GPS+ + +D + G V Y T G Y + F+ IP SPF + H V P S+V + N I V P I+N++C GS ++ +S + N+DG V T GVY + G K+ P KV +E V + ++V E + + A G GLQ+ + N F + N + L VT++GPS Q++C + G Y Y P V G Y I IT S + IPGSPF ++V Sbjct: 602 KVNAHGPGLTEGVVGEQAEFIIDTSRAGSGRLDVRVDGPSEVTLQCLDDQDGTCTVLYLPTEHGMYQINVLFDNSHIPGSPFGANI---------HHPVDP---SKVLVTNSALQHGI----------VGEPCIVNIDCAKV----GSEDLSVQAISDSGVVVETEVKENEDGTYTVVYVPRTGGVYTLLLK--YGGKVLPVHKVMVEQ-------KVYKSHVKVSRRGGVVVGERETDASQVVASGLGLQKGLIGHPNMFCV---NTRSPV----DDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISIT-SGENSIPGSPFVVSV 892 HSP 3 Score: 63.1586 bits (152), Expect = 3.960e-9 Identity = 82/344 (23.84%), Postives = 135/344 (39.24%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMD-KKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQ 5903 + E GD S+ V G L G ++FVV T G L + IEGPSK ++ + + G +SY PG Y +I F+ IP SPF V D R + K T+ +L F + + ++ V EP G SF + T ++ A +GVYN+ N K + I G T + PL + + +G LQ A F I W+ +L V+++GP ++++ E ++G I Y G Y + + + ++ H+ SPF ++V+ ++ ++ Q Sbjct: 1813 QAEIGDASK----VKAFGPGLHTGHTFCKSEFVVDTWDAGYGGLTVVIEGPSKVDVHTKELENDGTCNISYCPIKPGSYKISIKFSDEHIPGSPFTAVVKDQGLMR-----------ENITYNQKAAPTASIGSECSLAFKLQDVDPGTMSAHVYEPSG--SFGEAVILPSTGRDIYVVSFLAKEMGVYNVSIQN------------KGQTISGCPLQYT---------VGPLGRGG-SEKVQVWGQSLQTALATVPADFNI--WSREAGA----GALSVSVEGPGEIELLFDEQMDGSCIVTYTAQQPGDYEVSVMF-DEDHVSQSPFLVSVIAATDTAVSDQ 2110 HSP 4 Score: 63.1586 bits (152), Expect = 4.307e-9 Identity = 40/125 (32.00%), Postives = 60/125 (48.00%), Query Frame = 3 Query: 4851 ILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDIC 5225 + R + V D SQ V G L KG + N F V+T + +L + +EGPS +++ D G+Y V Y T+PGEY +I+ + IP SPF ++V D N ++ IC Sbjct: 791 VSRRGGVVVGERETDASQ----VVASGLGLQKGLIGHPNMFCVNTRSPV-DDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISITSGENSIPGSPFVVSVDDVSNTAGSGDCLQAGIC 910 HSP 5 Score: 60.8474 bits (146), Expect = 2.334e-8 Identity = 36/121 (29.75%), Postives = 55/121 (45.45%), Query Frame = 3 Query: 4860 LDSISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 L I +K+ D+ ++P + + G+ L G N F + L I IEGPS+A++ +D + G VSY T PG+Y + N V IP SPF+ + D R+ Sbjct: 1612 LHQILIKSAENDIPELPLQYYANSLANRSPVAYGRGLVCGIANETATFTICQEDSASSELDITIEGPSEADVHCLDNEDGTCSVSYLPTEPGDYEIQVQHNDVPIPGSPFKAKITDGHMRK 1732 HSP 6 Score: 56.6102 bits (135), Expect = 4.937e-7 Identity = 52/195 (26.67%), Postives = 92/195 (47.18%), Query Frame = 3 Query: 867 ISDYHIRQLDKPPDVIKDGR-VDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGN-GSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 I+D H+R+ + +K G VD + I E+DI++ L + GN C + L S IP +G + I K+ + N P + ++ + ++GPGL+ C F++DT + + +EGPSK + + N G+ I+Y + PG Y++SI ++E+I SP++ V+ Sbjct: 1725 ITDGHMRKSE-----VKLGSAVDFTLDI--TEEDISQ-LSASIMSPTGNDVPCLLK--TQADSHLGISFIPREAGEHLVSIMKD--GEHVSNSPISLSISQAEIGDASKVKAFGPGLHTGHTFCKSEFVVDTWDAGYGGLTVVIEGPSKVDVHTKELENDGTCNISYCPIKPGSYKISIKFSDEHIPGSPFTAVV 1907 HSP 7 Score: 52.7582 bits (125), Expect = 5.844e-6 Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3 Query: 1185 IVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +V+ G GL + P +F ++T +G ++EGPS ++ C + G G + Y+ +PG Y++SI E +I SP+ + + Sbjct: 809 VVASGLGLQKGLIGHPNMFCVNTRSPVDDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISITSGENSIPGSPFVVSV 892
BLAST of Filamin A vs. Ensembl Zebrafish
Match: CR352234.3 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529]) HSP 1 Score: 163.696 bits (413), Expect = 1.398e-39 Identity = 137/488 (28.07%), Postives = 225/488 (46.11%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430 +K +M T+ ++ + KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL +E ++L +I+ I+DG++K I L+W LI HYSI + + + + L W+ +KL I N S W SG A+G +V++C LC D W+ + ++NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN M A + + IS G V + ++ P ++ AK N K+ S +P ++G + + I PF V V + + + + GPGL G++A+ F + T G+ ++ + PS K +EC+ + GN S TY G + + I I SPY++ Sbjct: 24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 474 HSP 2 Score: 101.679 bits (252), Expect = 1.066e-20 Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903 ++V G L + +F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + VA D RR+ + S E K N + V N + V SP C VTE ++D + + G+Y ID F G I G +K+++ Q +P +V+ AYG GL+ T F + N S + +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPF KIT R NS H+ Sbjct: 2138 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2428 HSP 3 Score: 76.2554 bits (186), Expect = 5.533e-13 Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN F V+T G L++ IEGPSKA+IS D + G VSY +PG+Y + +N +IP SPF + D + R+ H V G++ I + ++ L +T P G +K + ++G + + +F+ +IG V I+ + S+ +S +IN + + + G GL +A F I ++ L ++I+GPSKV I+ + +G Y P G Y I I ++++ H+PGS F + V Sbjct: 1767 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2033 HSP 4 Score: 74.3294 bits (181), Expect = 1.795e-12 Identity = 84/314 (26.75%), Postives = 141/314 (44.90%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C + ++ ++ + G + + Y PG+YV + F IP+SPF++TV + L H+ + N G + + +G N + V+ +L T G G P K++K T NKDG + V +A T G++ +D +K + IH + + L VD VN ++ AYG GL VN+ +F N ++ E L + I+GPSK ISC ++ +G Y+P++ G Y I + Y++K +IPGSPF + D + ++H Sbjct: 1589 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTV-HTCHAHHLFIHIS-------FISNSGQTLTNGQLGMNGL-DVAGLRPFDLVIPFTIQKGEITGDVRMPSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1861 HSP 5 Score: 65.855 bits (159), Expect = 6.442e-10 Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L + +F++ T G L++ IEGPSK +I+ D++ G V+Y T PG Y+ I F +P S F + V + +K I K + S+ VG + PE I ++ VT P G H + M + N I + +GV+ + S K + +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +I+ + +G YI G Y + I ++++ HIP SPF + V P+ D Sbjct: 1940 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2230 HSP 6 Score: 64.6994 bits (156), Expect = 1.361e-9 Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484 SF P G++ I I I PF V + + ++GPGL V F+++ G D +GFS+EGPS KIEC + G+GS + Y PG Y + ++ E+I SP+ I+ + D KVK G Sbjct: 542 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 683 HSP 7 Score: 61.6178 bits (148), Expect = 1.305e-8 Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K ++ P +G ++ IK + + I P + V+ N + +YGPGL + + P VF ++T + + + ++EGPSK I C + +G+ ++Y +LPG Y + + N++NI SP+ Sbjct: 1723 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1847 HSP 8 Score: 56.6102 bits (135), Expect = 4.231e-7 Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3 Query: 924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + DL +KIP I IA ++ + +G V+K ++N +P G + +K + PF+ V + + + GPGL + A P F I + ++EGPSK +I + +GS ++Y PG Y++SI N+E+I DSP+ V+ ++ D+ +++ V L+ K Sbjct: 2058 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2245 HSP 9 Score: 53.1434 bits (126), Expect = 5.580e-6 Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3 Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180 KPT Q+I I + G +S+ PY V+V +LC KG V +F V+T G G+L + I+GP E K +G +Y Y + PG Y+ I++ IP SPF + + + Sbjct: 449 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 576 HSP 10 Score: 53.1434 bits (126), Expect = 5.580e-6 Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3 Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493 S + PFRV V + +GPGL + + P F ++T G+ MEGPS+ K+ C + +GS + Y PG Y L++ + I SP+S+ + + VD K K + GL N Sbjct: 1248 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1371
BLAST of Filamin A vs. Ensembl Zebrafish
Match: CR352234.2 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529]) HSP 1 Score: 163.696 bits (413), Expect = 1.398e-39 Identity = 137/488 (28.07%), Postives = 225/488 (46.11%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430 +K +M T+ ++ + KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL +E ++L +I+ I+DG++K I L+W LI HYSI + + + + L W+ +KL I N S W SG A+G +V++C LC D W+ + ++NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN M A + + IS G V + ++ P ++ AK N K+ S +P ++G + + I PF V V + + + + GPGL G++A+ F + T G+ ++ + PS K +EC+ + GN S TY G + + I I SPY++ Sbjct: 24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 474 HSP 2 Score: 101.679 bits (252), Expect = 1.066e-20 Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903 ++V G L + +F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + VA D RR+ + S E K N + V N + V SP C VTE ++D + + G+Y ID F G I G +K+++ Q +P +V+ AYG GL+ T F + N S + +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPF KIT R NS H+ Sbjct: 2138 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2428 HSP 3 Score: 76.2554 bits (186), Expect = 5.533e-13 Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN F V+T G L++ IEGPSKA+IS D + G VSY +PG+Y + +N +IP SPF + D + R+ H V G++ I + ++ L +T P G +K + ++G + + +F+ +IG V I+ + S+ +S +IN + + + G GL +A F I ++ L ++I+GPSKV I+ + +G Y P G Y I I ++++ H+PGS F + V Sbjct: 1767 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2033 HSP 4 Score: 74.3294 bits (181), Expect = 1.795e-12 Identity = 84/314 (26.75%), Postives = 141/314 (44.90%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C + ++ ++ + G + + Y PG+YV + F IP+SPF++TV + L H+ + N G + + +G N + V+ +L T G G P K++K T NKDG + V +A T G++ +D +K + IH + + L VD VN ++ AYG GL VN+ +F N ++ E L + I+GPSK ISC ++ +G Y+P++ G Y I + Y++K +IPGSPF + D + ++H Sbjct: 1589 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTV-HTCHAHHLFIHIS-------FISNSGQTLTNGQLGMNGL-DVAGLRPFDLVIPFTIQKGEITGDVRMPSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1861 HSP 5 Score: 65.855 bits (159), Expect = 6.442e-10 Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L + +F++ T G L++ IEGPSK +I+ D++ G V+Y T PG Y+ I F +P S F + V + +K I K + S+ VG + PE I ++ VT P G H + M + N I + +GV+ + S K + +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +I+ + +G YI G Y + I ++++ HIP SPF + V P+ D Sbjct: 1940 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2230 HSP 6 Score: 64.6994 bits (156), Expect = 1.361e-9 Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484 SF P G++ I I I PF V + + ++GPGL V F+++ G D +GFS+EGPS KIEC + G+GS + Y PG Y + ++ E+I SP+ I+ + D KVK G Sbjct: 542 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 683 HSP 7 Score: 61.6178 bits (148), Expect = 1.305e-8 Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K ++ P +G ++ IK + + I P + V+ N + +YGPGL + + P VF ++T + + + ++EGPSK I C + +G+ ++Y +LPG Y + + N++NI SP+ Sbjct: 1723 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1847 HSP 8 Score: 56.6102 bits (135), Expect = 4.231e-7 Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3 Query: 924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + DL +KIP I IA ++ + +G V+K ++N +P G + +K + PF+ V + + + GPGL + A P F I + ++EGPSK +I + +GS ++Y PG Y++SI N+E+I DSP+ V+ ++ D+ +++ V L+ K Sbjct: 2058 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2245 HSP 9 Score: 53.1434 bits (126), Expect = 5.580e-6 Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3 Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180 KPT Q+I I + G +S+ PY V+V +LC KG V +F V+T G G+L + I+GP E K +G +Y Y + PG Y+ I++ IP SPF + + + Sbjct: 449 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 576 HSP 10 Score: 53.1434 bits (126), Expect = 5.580e-6 Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3 Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493 S + PFRV V + +GPGL + + P F ++T G+ MEGPS+ K+ C + +GS + Y PG Y L++ + I SP+S+ + + VD K K + GL N Sbjct: 1248 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1371
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145]) HSP 1 Score: 162.54 bits (410), Expect = 3.038e-39 Identity = 138/489 (28.22%), Postives = 226/489 (46.22%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430 +K +M T+ ++ + KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL +E ++L +I+ I+DG++K I L+W LI HYSI + + + + L W+ +KL I N S W SG A+G +V++C LC D W+ + ++NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF + L + N K G + I+ GN M A + + IS G V + ++ P ++ AK N K+ S +P ++G + + I PF V V + + + + GPGL G++A+ F + T G+ ++ + PS K +EC+ + GN S TY G + + I I SPY++ Sbjct: 24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYG---PAGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 475 HSP 2 Score: 101.679 bits (252), Expect = 9.090e-21 Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903 ++V G L + +F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + VA D RR+ + S E K N + V N + V SP C VTE ++D + + G+Y ID F G I G +K+++ Q +P +V+ AYG GL+ T F + N S + +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPF KIT R NS H+ Sbjct: 2146 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2436 HSP 3 Score: 76.2554 bits (186), Expect = 4.963e-13 Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN F V+T G L++ IEGPSKA+IS D + G VSY +PG+Y + +N +IP SPF + D + R+ H V G++ I + ++ L +T P G +K + ++G + + +F+ +IG V I+ + S+ +S +IN + + + G GL +A F I ++ L ++I+GPSKV I+ + +G Y P G Y I I ++++ H+PGS F + V Sbjct: 1775 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2041 HSP 4 Score: 72.0182 bits (175), Expect = 8.360e-12 Identity = 80/320 (25.00%), Postives = 137/320 (42.81%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVAD-DVNRRILHKHVKPDICSEVEM-----------QNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C + ++ ++ + G + + Y PG+YV + F IP+SPF++T + D +++ + M N + ++P + F + EI V P G + K T NKDG + V +A T G++ +D +K + IH + + L VD VN ++ AYG GL VN+ +F N ++ E L + I+GPSK ISC ++ +G Y+P++ G Y I + Y++K +IPGSPF + D + ++H Sbjct: 1590 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTALEGDSPDQLMQQSQNLQYAYAPNMGQTWATDGQLGMNGLDVAGLRPFDLVIPFTIQKGEITG---DVRMPSG-----KVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVDY-------VNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1869 HSP 5 Score: 66.2402 bits (160), Expect = 5.925e-10 Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L + +F++ T G L++ IEGPSK +I+ D++ G V+Y T PG Y+ I F +P S F + V + +K I K + S+ VG + PE I ++ VT P G H + M + N I + +GV+ + S K + +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +I+ + +G YI G Y + I ++++ HIP SPF + V P+ D Sbjct: 1948 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2238 HSP 6 Score: 65.0846 bits (157), Expect = 1.316e-9 Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484 SF P G++ I I I PF V + + ++GPGL V F+++ G D +GFS+EGPS KIEC + G+GS + Y PG Y + ++ E+I SP+ I+ + D KVK G Sbjct: 543 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 684 HSP 7 Score: 61.6178 bits (148), Expect = 1.339e-8 Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K ++ P +G ++ IK + + I P + V+ N + +YGPGL + + P VF ++T + + + ++EGPSK I C + +G+ ++Y +LPG Y + + N++NI SP+ Sbjct: 1731 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1855 HSP 8 Score: 56.6102 bits (135), Expect = 4.681e-7 Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3 Query: 924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + DL +KIP I IA ++ + +G V+K ++N +P G + +K + PF+ V + + + GPGL + A P F I + ++EGPSK +I + +GS ++Y PG Y++SI N+E+I DSP+ V+ ++ D+ +++ V L+ K Sbjct: 2066 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2253 HSP 9 Score: 53.1434 bits (126), Expect = 5.352e-6 Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3 Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180 KPT Q+I I + G +S+ PY V+V +LC KG V +F V+T G G+L + I+GP E K +G +Y Y + PG Y+ I++ IP SPF + + + Sbjct: 450 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 577 HSP 10 Score: 53.1434 bits (126), Expect = 5.443e-6 Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3 Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493 S + PFRV V + +GPGL + + P F ++T G+ MEGPS+ K+ C + +GS + Y PG Y L++ + I SP+S+ + + VD K K + GL N Sbjct: 1249 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1372
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flncb (filamin C, gamma b (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-041008-175]) HSP 1 Score: 162.155 bits (409), Expect = 4.176e-39 Identity = 134/498 (26.91%), Postives = 222/498 (44.58%), Query Frame = 3 Query: 60 QEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNL----PNKKPTIVSYGPGL--YGSVADCP---------------GVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 +EM T+ ++ + KI++ FTRW N LK N+ I DLQ DL +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE + L W+ +K+ I+N W G A+G +V+ C LC D W+ S + NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF + R + K I+ GN + A + ++ G ++L+ I E + V+ D+N S +P + G +K +I PF V V+ PNK + + GPGL G+VA+ P GV I+D+ G + +E N G+ TY +L G + + + + I SP+++ I ++ Sbjct: 28 EEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCLNRKILDLQKDLTDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKLTPKQRLLGWIQNKVPQLHINNFHRDWRDGKALGALVDNCAPGLCPDWETWDPSQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKTLHPKRAKAYGPGIEPRGNVVLKPAEFVV---------------ETVEAGLGEVLVYIEDPEGHTEEARVIPNNDRN---------------RSYSVVYVPKVEGLHK--VKVLFAGQDIDRSPFLVNVSKALGDPNK---VQARGPGLEPVGNVANKPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILE----------NKGDSVFRCTYGPILEGPHTIYVTFAGQQIPRSPFTVHISEA 480 HSP 2 Score: 107.071 bits (266), Expect = 2.405e-22 Identity = 103/329 (31.31%), Postives = 143/329 (43.47%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA---DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEISF D+K G V+Y V PG+Y +I FN IP SPF + +A DD R+L + S EM K N + V N + V +P C++TE H I+ + + + GV++ID F G I G +K+++ Q +P +V A+G GL+ T + F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2364 HKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYIVQEPGDYEVSIKFNDEHIPDSPFIVPIASLSDDA--RLL------TVTSLQEMGLKVNQEASFAVQLNGARGAIDAKVHTPSGAVEECYITELDNDK--HAIRFIPREN-------------GVHSIDV-RFNGSHIPGSPFKIRVGEPG--------------QAGDPGMVT-------AFGPGLEGGTTGVPSDFIVNTCNAGSG------ALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV 2641 HSP 3 Score: 69.707 bits (169), Expect = 4.851e-11 Identity = 50/162 (30.86%), Postives = 83/162 (51.23%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY--SIVIVKSNKVDEIKKVKVIGLE------NKNTKSFIIDSRNS 1532 PI G + I + ++ I PF V ++ + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ S+ E K GLE NK + F ID+R + Sbjct: 589 PIFCGKYIITVTWGGHA--IPRSPFEVIISEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAASDVFPEKVKCYGPGLEPTGCIVNKPAE-FTIDARGA 747 HSP 4 Score: 63.5438 bits (153), Expect = 3.862e-9 Identity = 36/92 (39.13%), Postives = 47/92 (51.09%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V+ G L G VN + F + T G L++ +EGPSKAEIS D K G VSY T PG+Y + F+ I SPF + D + R Sbjct: 1910 VNAYGPGLSHGMVNKSATFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIAGSPFTAKITGDDSMR 2001 HSP 5 Score: 63.1586 bits (152), Expect = 4.236e-9 Identity = 40/132 (30.30%), Postives = 66/132 (50.00%), Query Frame = 3 Query: 1047 SNEL-SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 SNE+ + IP G + + I + + PF V +P + +YGPGL G + P F +DT G+ +EGP + KIEC + G+GS ++Y PG Y ++I+ + +I SP+ ++ Sbjct: 1070 SNEVHTVKYIPPEEGPYKVDISYD--GNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFADAHIPGSPFKAMV 1199 HSP 6 Score: 63.1586 bits (152), Expect = 5.096e-9 Identity = 81/338 (23.96%), Postives = 134/338 (39.64%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTS--GKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKP-DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV--LRDPN 5885 P +V G L +G VN F V S G+ + I + ++AE+ + G Y ++Y G Y I + +P P R+ V D ++ V+P + EV ++ +G N I + +P N + +VT+ G+ ++ T+ +DG I V + V F + + PS + AYG GL++ VN+ N F + E+ L + I+GPS+ ++SC ++ +G YIP G Y + IT+ IPGSPF++ V L DP+ Sbjct: 1205 PSKVTASGPGLERGKVNEAGSFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITIKYGGHAVPKFPARVQVDPALDTSGIKVYGPGVEPRGVLREVTTHFIVDTRVHNKMGGNHIKVRIVNPSGANTDAYVTDKADGTY-----RVEYTAYEDGVHLIEVLYDDVPVPKSPFRVAVAEGCDPS------------------------------------RVRAYGPGLEEGLVNKPNRFTV------ETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGEYDVNITFGG-LPIPGSPFRVPVRELVDPS 1494 HSP 7 Score: 58.151 bits (139), Expect = 1.569e-7 Identity = 41/119 (34.45%), Postives = 57/119 (47.90%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228 ++E GD S+ V V GK L +G +F+V T G L + IEGPSK +I+ D G V+Y T PG Y+ I F +P SPF + V + + I K P I + Sbjct: 2083 QSEIGDASK----VKVSGKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRMKESITRKRQAPSIAT 2197 HSP 8 Score: 56.9954 bits (136), Expect = 3.486e-7 Identity = 39/130 (30.00%), Postives = 66/130 (50.77%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 ++ + IP +G I ++ N I PF++ V P + P +V ++GPGL G P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI ++I SP+ Sbjct: 2511 DKHAIRFIPRENGVHSIDVRFN--GSHIPGSPFKIRVGEPGQAGDPGMVTAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEG-YKVTYTPMAPGSYLISIKYGGPQHIVGSPF 2637 HSP 9 Score: 54.6842 bits (130), Expect = 1.608e-6 Identity = 38/140 (27.14%), Postives = 69/140 (49.29%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVN---LPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 + S P G + +KKN + N PF++ V + + VS G GL FI+DT + +G S+EGPSK I C+++ +G+ +TY PG Y ++I ++++ SP+++ ++ ++ E Sbjct: 2048 HIGISFTPKEVGEHVVSVKKN--GKHVTNSPFKIMVGQSEIGDASKVKVS-GKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRMKE 2184
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 164.081 bits (414), Expect = 1.415e-39 Identity = 138/512 (26.95%), Postives = 230/512 (44.92%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNSTFEMP 1547 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ ++ FS Q ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K+ L W+ +K+ I N S W G A+G +V++C LC D W+ + NA+ AM+ A +PQ++ P EIID + + ++MTY+SQF L+ + N K + ++ GN A + + IS G ++L+ I D GN + GN K+ S +P ++G + + I PF V V + + + GPGL G++A+ P F + T G+ IG + P + ++ + GN TY + G + ++I E SPY + I ++ + + ++ G+ + T F +D++ + P Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAAGMVEP 488 HSP 2 Score: 112.849 bits (281), Expect = 5.112e-24 Identity = 102/317 (32.18%), Postives = 142/317 (44.79%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFK 5861 G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y I FN IP SPF + + +DD R + + + N+ S +I+ G + V SP CFVTE P K + ++ G++ ID F G + G +KV++ Q +P +V AYGDGL+ T +++ F I N S++ +L VTI+GPSKV + C E GY Y P+ G+Y IG+ Y HI GSPFK Sbjct: 2170 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFK 2438 HSP 3 Score: 82.4185 bits (202), Expect = 9.811e-15 Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3 Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 F P+ G + + I + I PF V V L + ++GPGLY +A F++++ GS+ +GF++EGPS+ KIEC + G+GS + Y PG Y + IM ++E+I +SPY +I ++ + KVK G Sbjct: 510 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 649 HSP 4 Score: 70.0922 bits (170), Expect = 4.613e-11 Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K +S +P +G ++ IK N I P + VN PN ++ +YGPGL VA+ P F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+ +I SP+ Sbjct: 1750 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1874 HSP 5 Score: 70.0922 bits (170), Expect = 4.691e-11 Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PGNLA+ + SKAE++ D K G Y V+Y G Y A+ + +P P R+ V V+ + K P I E ++ S+ G N HV + +T P G S+ + ++ N DG ++ G + I D+ P+ K+ T C D + A G GL +A N+ N F S+I + L +T++GPS+ ++SC ++ +G Y P V G Y + ITY + HIPGSPF++ V Sbjct: 1127 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1409 HSP 6 Score: 68.1662 bits (165), Expect = 2.221e-10 Identity = 83/309 (26.86%), Postives = 120/309 (38.83%), Query Frame = 3 Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKG--NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867 FVV + G + I GP + E ++ G Y + Y G YV + F DIP+SPF + V SE + G N S +P + F + + EI V P G ++ I NKDG +++ ++ + G L + C+ +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y N HI GSPF KIT Sbjct: 1630 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMV------------------SETDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1879 HSP 7 Score: 66.2402 bits (160), Expect = 7.201e-10 Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N I SPF + DD RR Sbjct: 1794 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1885 HSP 8 Score: 61.2326 bits (147), Expect = 2.583e-8 Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351 P V G L + N N F V T G G L I +EGPS++++S D K G V Y + G+Y I+++ IP SPFR+ V D V+ S+V++ G T+++ + + S I L VT P G Sbjct: 1322 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1458 HSP 9 Score: 60.8474 bits (146), Expect = 3.645e-8 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V LP + +YGPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1019 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1117 HSP 10 Score: 59.3066 bits (142), Expect = 8.517e-8 Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873 ++E GD S+ V G L +G + F+V T G L++ +EGPSK +I D + G VSY T PG Y+ +I F +P SPF V + V I + P + S VG ++ PEI L V P G I + + ++ F+ G++ + S K + E++ GS T + PL + + A G GL++ F I W L + ++GPSK +IS + +G Y+ G Y + I ++++ HIP SPF + ++ Sbjct: 1966 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2251 HSP 11 Score: 58.9214 bits (141), Expect = 1.352e-7 Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384 G +G +EGP E+++ C DG +++ P G Y++ +T DG+ I GSPF + V + D P + + Q + ++ K G P V+ T+ Sbjct: 1353 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1460 HSP 12 Score: 54.6842 bits (130), Expect = 2.581e-6 Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 N + S IP G + IKKN I N P + V + ++GPGL FI+DT + + ++EGPSK I+ ++ +G+ ++Y PG+Y +SI +E++ SP++ ++ +V E Sbjct: 1930 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2067 HSP 13 Score: 52.7582 bits (125), Expect = 9.817e-6 Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532 + N PF+V V + + G GL ++ + P +F + T G+ +G ++EGPS++K+ C + +GS + Y+ + G Y ++I + E+I SP+ + + V + KVK+ G + K + F +D+ + Sbjct: 1307 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1444
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 163.696 bits (413), Expect = 1.780e-39 Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ ++ FS Q ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K+ L W+ +K+ I N S W G A+G +V++C LC D W+ + NA+ AM+ A +PQ++ P EIID + + ++MTY+SQF L+ + N K + ++ GN A + + IS G ++L+ I D GN + GN K+ S +P ++G + + I PF V V + + + GPGL G++A+ P F + T G+ IG + P + ++ + GN TY + G + ++I E SPY + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483 HSP 2 Score: 115.931 bits (289), Expect = 6.229e-25 Identity = 103/320 (32.19%), Postives = 146/320 (45.62%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y I FN IP SPF + + +DD R + + + N+ S +I+ G + V SP CFVTE G+ + ++ M + + G++ ID F G + G +KV++ Q +P +V AYGDGL+ T +++ F I N S++ +L VTI+GPSKV + C E GY Y P+ G+Y IG+ Y HI GSPFK V Sbjct: 2231 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTELEPGN--YAVRFMPREN-------------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2502 HSP 3 Score: 82.4185 bits (202), Expect = 9.288e-15 Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3 Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 F P+ G + + I + I PF V V L + ++GPGLY +A F++++ GS+ +GF++EGPS+ KIEC + G+GS + Y PG Y + IM ++E+I +SPY +I ++ + KVK G Sbjct: 514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653 HSP 4 Score: 73.9442 bits (180), Expect = 3.065e-12 Identity = 84/315 (26.67%), Postives = 127/315 (40.32%), Query Frame = 3 Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKP------DICSEVEMQNKG--NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867 FVV + G + I GP + E ++ G Y + Y G YV + F DIP+SPF + D+V ++ + + + SE + G N S +P + F + + EI V P G ++ I NKDG +++ ++ + G L + C+ +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y N HI GSPF KIT Sbjct: 1667 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMATDEVPVQVQQQSLSACPPGYQPLVSETDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1940 HSP 5 Score: 70.0922 bits (170), Expect = 4.706e-11 Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PGNLA+ + SKAE++ D K G Y V+Y G Y A+ + +P P R+ V V+ + K P I E ++ S+ G N HV + +T P G S+ + ++ N DG ++ G + I D+ P+ K+ T C D + A G GL +A N+ N F S+I + L +T++GPS+ ++SC ++ +G Y P V G Y + ITY + HIPGSPF++ V Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416 HSP 6 Score: 70.0922 bits (170), Expect = 4.826e-11 Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K +S +P +G ++ IK N I P + VN PN ++ +YGPGL VA+ P F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+ +I SP+ Sbjct: 1811 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1935 HSP 7 Score: 66.2402 bits (160), Expect = 7.223e-10 Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N I SPF + DD RR Sbjct: 1855 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1946 HSP 8 Score: 60.8474 bits (146), Expect = 3.625e-8 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V LP + +YGPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124 HSP 9 Score: 59.6918 bits (143), Expect = 6.693e-8 Identity = 35/93 (37.63%), Postives = 48/93 (51.61%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + N N F V T G G L I +EGPS++++S D K G V Y + G+Y I+++ IP SPFR+ V D V+ Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVD 1421 HSP 10 Score: 59.3066 bits (142), Expect = 8.540e-8 Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873 ++E GD S+ V G L +G + F+V T G L++ +EGPSK +I D + G VSY T PG Y+ +I F +P SPF V + V I + P + S VG ++ PEI L V P G I + + ++ F+ G++ + S K + E++ GS T + PL + + A G GL++ F I W L + ++GPSK +IS + +G Y+ G Y + I ++++ HIP SPF + ++ Sbjct: 2027 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2312 HSP 11 Score: 56.6102 bits (135), Expect = 6.578e-7 Identity = 28/103 (27.18%), Postives = 48/103 (46.60%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSS 2369 G +G +EGP E+++ C DG +++ P G Y++ +T DG+ I GSPF + V + D P + + Q + ++ K G P V+ Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTG 1462 HSP 12 Score: 54.6842 bits (130), Expect = 2.460e-6 Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 N + S IP G + IKKN I N P + V + ++GPGL FI+DT + + ++EGPSK I+ ++ +G+ ++Y PG+Y +SI +E++ SP++ ++ +V E Sbjct: 1991 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2128 HSP 13 Score: 52.7582 bits (125), Expect = 9.435e-6 Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532 + N PF+V V + + G GL ++ + P +F + T G+ +G ++EGPS++K+ C + +GS + Y+ + G Y ++I + E+I SP+ + + V + KVK+ G + K + F +D+ + Sbjct: 1314 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1451
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 163.696 bits (413), Expect = 2.192e-39 Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ ++ FS Q ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K+ L W+ +K+ I N S W G A+G +V++C LC D W+ + NA+ AM+ A +PQ++ P EIID + + ++MTY+SQF L+ + N K + ++ GN A + + IS G ++L+ I D GN + GN K+ S +P ++G + + I PF V V + + + GPGL G++A+ P F + T G+ IG + P + ++ + GN TY + G + ++I E SPY + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483 HSP 2 Score: 113.62 bits (283), Expect = 3.289e-24 Identity = 103/320 (32.19%), Postives = 143/320 (44.69%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y I FN IP SPF + + +DD R + + + N+ S +I+ G + V SP CFVTE P K + ++ G++ ID F G + G +KV++ Q +P +V AYGDGL+ T +++ F I N S++ +L VTI+GPSKV + C E GY Y P+ G+Y IG+ Y HI GSPFK V Sbjct: 2216 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2487 HSP 3 Score: 82.4185 bits (202), Expect = 9.678e-15 Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3 Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 F P+ G + + I + I PF V V L + ++GPGLY +A F++++ GS+ +GF++EGPS+ KIEC + G+GS + Y PG Y + IM ++E+I +SPY +I ++ + KVK G Sbjct: 514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653 HSP 4 Score: 70.0922 bits (170), Expect = 4.742e-11 Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K +S +P +G ++ IK N I P + VN PN ++ +YGPGL VA+ P F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+ +I SP+ Sbjct: 1765 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1889 HSP 5 Score: 70.0922 bits (170), Expect = 4.823e-11 Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PGNLA+ + SKAE++ D K G Y V+Y G Y A+ + +P P R+ V V+ + K P I E ++ S+ G N HV + +T P G S+ + ++ N DG ++ G + I D+ P+ K+ T C D + A G GL +A N+ N F S+I + L +T++GPS+ ++SC ++ +G Y P V G Y + ITY + HIPGSPF++ V Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416 HSP 6 Score: 66.2402 bits (160), Expect = 7.279e-10 Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N I SPF + DD RR Sbjct: 1809 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1900 HSP 7 Score: 63.929 bits (154), Expect = 3.563e-9 Identity = 79/307 (25.73%), Postives = 117/307 (38.11%), Query Frame = 3 Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867 FVV + G + I GP + E ++ G Y + Y G YV + F DIP+SPF + ++ N S +P + F + + EI V P G ++ I NKDG +++ ++ + G L + C+ +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y N HI GSPF KIT Sbjct: 1648 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVM-------------------TDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1894 HSP 8 Score: 61.2326 bits (147), Expect = 2.610e-8 Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351 P V G L + N N F V T G G L I +EGPS++++S D K G V Y + G+Y I+++ IP SPFR+ V D V+ S+V++ G T+++ + + S I L VT P G Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1465 HSP 9 Score: 60.8474 bits (146), Expect = 3.592e-8 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V LP + +YGPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124 HSP 10 Score: 58.9214 bits (141), Expect = 1.389e-7 Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384 G +G +EGP E+++ C DG +++ P G Y++ +T DG+ I GSPF + V + D P + + Q + ++ K G P V+ T+ Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1467 HSP 11 Score: 56.225 bits (134), Expect = 7.778e-7 Identity = 86/353 (24.36%), Postives = 141/353 (39.94%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-------EVEMQNKGNSTSIKPVGKNLIFH---------VSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873 ++E GD S+ V G L +G + F+V T G L++ +EGPSK +I D + G VSY T PG Y+ +I F +P SPF V + V I + P + S +++ KG P+ + H +SS +I L V P G I + + ++ F+ G++ + S K + E++ GS T + PL + + A G GL++ F I W L + ++GPSK +IS + +G Y+ G Y + I ++++ HIP SPF + ++ Sbjct: 1981 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVASVGGLCELNLKIPGKGVQKVWAPLINSNEGHYFVESQTKQISSAKIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2297 HSP 12 Score: 54.6842 bits (130), Expect = 2.480e-6 Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 N + S IP G + IKKN I N P + V + ++GPGL FI+DT + + ++EGPSK I+ ++ +G+ ++Y PG+Y +SI +E++ SP++ ++ +V E Sbjct: 1945 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2082 HSP 13 Score: 52.7582 bits (125), Expect = 8.966e-6 Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532 + N PF+V V + + G GL ++ + P +F + T G+ +G ++EGPS++K+ C + +GS + Y+ + G Y ++I + E+I SP+ + + V + KVK+ G + K + F +D+ + Sbjct: 1314 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1451
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 163.696 bits (413), Expect = 2.250e-39 Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ ++ FS Q ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K+ L W+ +K+ I N S W G A+G +V++C LC D W+ + NA+ AM+ A +PQ++ P EIID + + ++MTY+SQF L+ + N K + ++ GN A + + IS G ++L+ I D GN + GN K+ S +P ++G + + I PF V V + + + GPGL G++A+ P F + T G+ IG + P + ++ + GN TY + G + ++I E SPY + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483 HSP 2 Score: 113.62 bits (283), Expect = 3.112e-24 Identity = 103/320 (32.19%), Postives = 143/320 (44.69%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y I FN IP SPF + + +DD R + + + N+ S +I+ G + V SP CFVTE P K + ++ G++ ID F G + G +KV++ Q +P +V AYGDGL+ T +++ F I N S++ +L VTI+GPSKV + C E GY Y P+ G+Y IG+ Y HI GSPFK V Sbjct: 2165 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2436 HSP 3 Score: 82.0333 bits (201), Expect = 1.132e-14 Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3 Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 F P+ G + + I + I PF V V L + ++GPGLY +A F++++ GS+ +GF++EGPS+ KIEC + G+GS + Y PG Y + IM ++E+I +SPY +I ++ + KVK G Sbjct: 514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653 HSP 4 Score: 70.0922 bits (170), Expect = 4.691e-11 Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PGNLA+ + SKAE++ D K G Y V+Y G Y A+ + +P P R+ V V+ + K P I E ++ S+ G N HV + +T P G S+ + ++ N DG ++ G + I D+ P+ K+ T C D + A G GL +A N+ N F S+I + L +T++GPS+ ++SC ++ +G Y P V G Y + ITY + HIPGSPF++ V Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416 HSP 5 Score: 70.0922 bits (170), Expect = 5.189e-11 Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K +S +P +G ++ IK N I P + VN PN ++ +YGPGL VA+ P F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+ +I SP+ Sbjct: 1745 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1869 HSP 6 Score: 66.2402 bits (160), Expect = 7.202e-10 Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N I SPF + DD RR Sbjct: 1789 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1880 HSP 7 Score: 61.2326 bits (147), Expect = 2.605e-8 Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351 P V G L + N N F V T G G L I +EGPS++++S D K G V Y + G+Y I+++ IP SPFR+ V D V+ S+V++ G T+++ + + S I L VT P G Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1465 HSP 8 Score: 60.4622 bits (145), Expect = 3.899e-8 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V LP + +YGPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124 HSP 9 Score: 59.3066 bits (142), Expect = 8.518e-8 Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873 ++E GD S+ V G L +G + F+V T G L++ +EGPSK +I D + G VSY T PG Y+ +I F +P SPF V + V I + P + S VG ++ PEI L V P G I + + ++ F+ G++ + S K + E++ GS T + PL + + A G GL++ F I W L + ++GPSK +IS + +G Y+ G Y + I ++++ HIP SPF + ++ Sbjct: 1961 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2246 HSP 10 Score: 58.5362 bits (140), Expect = 1.496e-7 Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384 G +G +EGP E+++ C DG +++ P G Y++ +T DG+ I GSPF + V + D P + + Q + ++ K G P V+ T+ Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1467 HSP 11 Score: 55.0694 bits (131), Expect = 1.696e-6 Identity = 37/94 (39.36%), Postives = 50/94 (53.19%), Query Frame = 3 Query: 5595 NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867 ++ AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y N HI GSPF KIT Sbjct: 1788 SVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1874 HSP 12 Score: 54.6842 bits (130), Expect = 2.692e-6 Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 N + S IP G + IKKN I N P + V + ++GPGL FI+DT + + ++EGPSK I+ ++ +G+ ++Y PG+Y +SI +E++ SP++ ++ +V E Sbjct: 1925 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2062
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 163.31 bits (412), Expect = 2.301e-39 Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ ++ FS Q ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K+ L W+ +K+ I N S W G A+G +V++C LC D W+ + NA+ AM+ A +PQ++ P EIID + + ++MTY+SQF L+ + N K + ++ GN A + + IS G ++L+ I D GN + GN K+ S +P ++G + + I PF V V + + + GPGL G++A+ P F + T G+ IG + P + ++ + GN TY + G + ++I E SPY + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483 HSP 2 Score: 114.775 bits (286), Expect = 1.405e-24 Identity = 103/321 (32.09%), Postives = 141/321 (43.93%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRI---LHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y I FN IP SPF + + +DD R L +K + + ++ G I V SP CFVTE P K + ++ G++ ID F G + G +KV++ Q +P +V AYGDGL+ T +++ F I N S++ +L VTI+GPSKV + C E GY Y P+ G+Y IG+ Y HI GSPFK V Sbjct: 2203 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQSGLKVNQPASFAIRLNGARGKIDA-------KVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2473 HSP 3 Score: 82.4185 bits (202), Expect = 8.816e-15 Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3 Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 F P+ G + + I + I PF V V L + ++GPGLY +A F++++ GS+ +GF++EGPS+ KIEC + G+GS + Y PG Y + IM ++E+I +SPY +I ++ + KVK G Sbjct: 505 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 644 HSP 4 Score: 70.4774 bits (171), Expect = 3.652e-11 Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PGNLA+ + SKAE++ D K G Y V+Y G Y A+ + +P P R+ V V+ + K P I E ++ S+ G N HV + +T P G S+ + ++ N DG ++ G + I D+ P+ K+ T C D + A G GL +A N+ N F S+I + L +T++GPS+ ++SC ++ +G Y P V G Y + ITY + HIPGSPF++ V Sbjct: 1125 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1407 HSP 5 Score: 70.4774 bits (171), Expect = 4.285e-11 Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K +S +P +G ++ IK N I P + VN PN ++ +YGPGL VA+ P F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+ +I SP+ Sbjct: 1737 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1861 HSP 6 Score: 66.6254 bits (161), Expect = 6.577e-10 Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N I SPF + DD RR Sbjct: 1781 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1872 HSP 7 Score: 65.0846 bits (157), Expect = 1.788e-9 Identity = 80/307 (26.06%), Postives = 116/307 (37.79%), Query Frame = 3 Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867 FVV + G + I GP + E ++ G Y + Y G YV + F DIP+SPF + V N S +P + F + + EI V P G ++ I NKDG +++ ++ + G L + C+ +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y N HI GSPF KIT Sbjct: 1625 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMVG------------------------SMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1866 HSP 8 Score: 61.2326 bits (147), Expect = 2.262e-8 Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351 P V G L + N N F V T G G L I +EGPS++++S D K G V Y + G+Y I+++ IP SPFR+ V D V+ S+V++ G T+++ + + S I L VT P G Sbjct: 1320 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1456 HSP 9 Score: 60.8474 bits (146), Expect = 3.590e-8 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V LP + +YGPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1017 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1115 HSP 10 Score: 58.9214 bits (141), Expect = 1.400e-7 Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384 G +G +EGP E+++ C DG +++ P G Y++ +T DG+ I GSPF + V + D P + + Q + ++ K G P V+ T+ Sbjct: 1351 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1458 HSP 11 Score: 55.8398 bits (133), Expect = 1.125e-6 Identity = 39/119 (32.77%), Postives = 56/119 (47.06%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228 ++E GD S+ V G L +G + F+V T G L++ +EGPSK +I D + G VSY T PG Y+ +I F +P SPF V + V I + P + S Sbjct: 1953 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS 2067 HSP 12 Score: 54.6842 bits (130), Expect = 2.317e-6 Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 N + S IP G + IKKN I N P + V + ++GPGL FI+DT + + ++EGPSK I+ ++ +G+ ++Y PG+Y +SI +E++ SP++ ++ +V E Sbjct: 1917 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2054 HSP 13 Score: 52.7582 bits (125), Expect = 8.887e-6 Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532 + N PF+V V + + G GL ++ + P +F + T G+ +G ++EGPS++K+ C + +GS + Y+ + G Y ++I + E+I SP+ + + V + KVK+ G + K + F +D+ + Sbjct: 1305 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1442
BLAST of Filamin A vs. Ensembl Mouse
Match: Flnb (filamin, beta [Source:MGI Symbol;Acc:MGI:2446089]) HSP 1 Score: 163.696 bits (413), Expect = 1.684e-39 Identity = 135/502 (26.89%), Postives = 227/502 (45.22%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ + E + + V DKN S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + + + I SP+ + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMVFVEDPEGNKEEARVTPDSDKN---------------KTYSVEYLPKVTGLHKVIVLFA--GQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAA 482 HSP 2 Score: 98.5969 bits (244), Expect = 9.068e-20 Identity = 94/321 (29.28%), Postives = 139/321 (43.30%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV-ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V A + R L + + +Q G + +P + + + +I + V P G + ++ FI G++ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI N +++ +L VTI+GPSKV++ C E GY Y P+ G Y IG+ Y HI SPFK V Sbjct: 2194 HKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCL---------TVLSLQESGLKVN-QPASFAIRLNGAKGKI---DAKVHSPSGAVEECHVSELEPDKYAVRFI---PHENGIHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGAGLETGTTGIQSEFFI---NTTQA---GPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKV 2471 HSP 3 Score: 85.5001 bits (210), Expect = 8.585e-16 Identity = 79/319 (24.76%), Postives = 135/319 (42.32%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD NRR CS+V++ + + + +S ++ L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDD-NRR----------CSQVKLGS----------AADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGQGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089 HSP 4 Score: 81.6481 bits (200), Expect = 1.243e-14 Identity = 88/317 (27.76%), Postives = 129/317 (40.69%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK I ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V +P + E + + N KP + F V EI V P G + I NKDG + V + P+ +V + +H R + + +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGT---VHMPSGKKATPEI-----VDNKDGTVTV------------------RYAPT-EVGLHEMHIKYRGSHIP-------ESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911 HSP 5 Score: 72.7886 bits (177), Expect = 5.794e-12 Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI--VKSNKVDEIKKVKVIGLENK-----NTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQR 1745 SF P G + + + + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I + ++ + GLE N FI+D +++ P + D G + + + ++ Y PL + I V + V + PY ++ + Q+ Sbjct: 512 SFEYYPSTPGKYSVAVTWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAG-SAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVV-WGGVNIPHSPYRVNIGQGSHPQK 744 HSP 6 Score: 71.2478 bits (173), Expect = 1.685e-11 Identity = 84/342 (24.56%), Postives = 145/342 (42.40%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + R + + ++ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1995 VQSEIGDARR----AKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVR-------------ESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGIPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPDSPYLVPVIA-PSDD 2286 HSP 7 Score: 65.855 bits (159), Expect = 8.177e-10 Identity = 37/93 (39.78%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P VH G L + F N +N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ V IP SPFR+ D V+ Sbjct: 1328 PSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVD 1420 HSP 8 Score: 63.929 bits (154), Expect = 2.909e-9 Identity = 40/137 (29.20%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I N+ Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKYR--GSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNR 1913 HSP 9 Score: 62.003 bits (149), Expect = 1.203e-8 Identity = 79/330 (23.94%), Postives = 128/330 (38.79%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKP-----DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P + V ++ + K P D+ E +S + VG + I +++P + CFV + G+ ++ T + GF + V + + N F + + PS +H A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ Sbjct: 1133 PSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGI-KAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTY-----QVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPS------RVH------------------------------AQGPGLKEAFTNKSNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-VHIPGSPFRV 1413 HSP 10 Score: 60.077 bits (144), Expect = 3.902e-8 Identity = 92/415 (22.17%), Postives = 161/415 (38.80%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKN------TKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIE--LSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 + I N PF+V V + + + GPGL + + VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ V S V + KVK+ G + +SF +DS + P +V G+ +V + + P IV V Y ++ P+ + YD+++ S + +E D DA E L+VQ + + K + T +++ T+ +I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ ++ Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGP-YIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVE-FAIDARDAGEGLLAVQ----------ITDQEGKP---QRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD 1706 HSP 11 Score: 59.3066 bits (142), Expect = 7.085e-8 Identity = 36/120 (30.00%), Postives = 62/120 (51.67%), Query Frame = 3 Query: 1068 LIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 IP G F + + + + + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1006 FIPREEGLFAVDVTYDGHP--VPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 55.8398 bits (133), Expect = 7.834e-7 Identity = 55/212 (25.94%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G+V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I DSPY + ++ + D+ + + V+ L+ K Sbjct: 2099 ITRTSRAPAVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPS--DDARCLTVLSLQESGLK 2301 HSP 13 Score: 53.1434 bits (126), Expect = 6.034e-6 Identity = 89/350 (25.43%), Postives = 129/350 (36.86%), Query Frame = 3 Query: 4881 TESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIF-HVSSPEILNLNCFVTEP-----HGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIG--PSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDV-------TIDGPSKVQISCIEDING---YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 T L P +V G L G V +F + T G G L + +EGP +A+I D G VSY T PGEY I F +V IP SPF+ +++EM + + + G L V P IL ++C P S ++S +NKDG + T G+Y + + G+ + P+W VK+E P I I A+G G++ V R+ ++ + P V I PS C N Y Y P G + + +TY + IP SPFK+ V Sbjct: 1031 TVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFK---------------------ADIEM--PFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTM-KYGGELVPHFPAW-VKVE---------------------PAIDT---SGIKAFGPGIEGKDVFRE--------ATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDD-VPIPNSPFKVAV 1322
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 152.525 bits (384), Expect = 3.803e-38 Identity = 92/244 (37.70%), Postives = 140/244 (57.38%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 ++ EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S +NNA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF Sbjct: 11 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQF 252
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 159.073 bits (401), Expect = 4.086e-38 Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 ++ EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S +NNA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ ++ ++ P+ K + G+ + +Y + G++ + + I SPY++ + ++ Sbjct: 23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477 HSP 2 Score: 106.686 bits (265), Expect = 3.536e-22 Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + V +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + G+Y ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2231 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508 HSP 3 Score: 81.2629 bits (199), Expect = 1.774e-14 Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + S T NKDG + V S G++ +D ++ +N+H + + L VD VN +I AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y+++ HIPGSPF V D + ++H Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1954 HSP 4 Score: 76.2554 bits (186), Expect = 4.906e-13 Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ + ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + DT + D T +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.707 bits (169), Expect = 4.744e-11 Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ +G + + PE I ++ VT P G + H ++ + N I + +G++ + S K K +++ GS T + PL ++ + A G GL++A V F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323 HSP 6 Score: 68.9366 bits (167), Expect = 9.773e-11 Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N IP SPF V D + R+ H V Sbjct: 1864 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1957 HSP 7 Score: 67.0106 bits (162), Expect = 3.116e-10 Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583 F P + G++ + I I PF V V + ++GPGL G + F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I ++ + +VK GLE F +D++++ + P V+ D G S Sbjct: 539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718 HSP 8 Score: 59.6918 bits (143), Expect = 5.800e-8 Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N I +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + N+++I SP++ + Sbjct: 1816 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1944 HSP 9 Score: 58.9214 bits (141), Expect = 8.394e-8 Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK + ++ P DV G+ + V +K F ++C L+V V Sbjct: 2378 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2586
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 159.073 bits (401), Expect = 4.086e-38 Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 ++ EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S +NNA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ ++ ++ P+ K + G+ + +Y + G++ + + I SPY++ + ++ Sbjct: 23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477 HSP 2 Score: 106.686 bits (265), Expect = 3.536e-22 Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + V +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + G+Y ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2231 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508 HSP 3 Score: 81.2629 bits (199), Expect = 1.774e-14 Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + S T NKDG + V S G++ +D ++ +N+H + + L VD VN +I AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y+++ HIPGSPF V D + ++H Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1954 HSP 4 Score: 76.2554 bits (186), Expect = 4.906e-13 Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ + ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + DT + D T +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.707 bits (169), Expect = 4.744e-11 Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ +G + + PE I ++ VT P G + H ++ + N I + +G++ + S K K +++ GS T + PL ++ + A G GL++A V F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323 HSP 6 Score: 68.9366 bits (167), Expect = 9.773e-11 Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N IP SPF V D + R+ H V Sbjct: 1864 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1957 HSP 7 Score: 67.0106 bits (162), Expect = 3.116e-10 Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583 F P + G++ + I I PF V V + ++GPGL G + F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I ++ + +VK GLE F +D++++ + P V+ D G S Sbjct: 539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718 HSP 8 Score: 59.6918 bits (143), Expect = 5.800e-8 Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N I +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + N+++I SP++ + Sbjct: 1816 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1944 HSP 9 Score: 58.9214 bits (141), Expect = 8.394e-8 Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK + ++ P DV G+ + V +K F ++C L+V V Sbjct: 2378 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2586
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 158.688 bits (400), Expect = 4.450e-38 Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 ++ EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S +NNA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ ++ ++ P+ K + G+ + +Y + G++ + + I SPY++ + ++ Sbjct: 23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477 HSP 2 Score: 106.301 bits (264), Expect = 3.816e-22 Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + V +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + G+Y ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2239 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 80.8777 bits (198), Expect = 1.835e-14 Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + S T NKDG + V S G++ +D ++ +N+H + + L VD VN +I AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y+++ HIPGSPF V D + ++H Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1962 HSP 4 Score: 76.2554 bits (186), Expect = 5.076e-13 Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ + ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + DT + D T +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.707 bits (169), Expect = 5.162e-11 Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ +G + + PE I ++ VT P G + H ++ + N I + +G++ + S K K +++ GS T + PL ++ + A G GL++A V F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331 HSP 6 Score: 68.5514 bits (166), Expect = 1.003e-10 Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N IP SPF V D + R+ H V Sbjct: 1872 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1965 HSP 7 Score: 67.0106 bits (162), Expect = 3.448e-10 Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583 F P + G++ + I I PF V V + ++GPGL G + F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I ++ + +VK GLE F +D++++ + P V+ D G S Sbjct: 539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718 HSP 8 Score: 59.6918 bits (143), Expect = 6.050e-8 Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N I +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + N+++I SP++ + Sbjct: 1824 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1952 HSP 9 Score: 58.9214 bits (141), Expect = 8.905e-8 Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK + ++ P DV G+ + V +K F ++C L+V V Sbjct: 2386 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2594
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|O75369|FLNB_HUMAN (Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2) HSP 1 Score: 164.081 bits (414), Expect = 8.203e-39 Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ VE D GN + + K+ S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + I + I SP+ + + ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482 HSP 2 Score: 90.8929 bits (224), Expect = 1.288e-16 Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V +DD R + + + N+ S +I+ G + V SP C V+E P K + GV+ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI + +L VTI+GPSKV++ C E GY Y P+ G Y I + Y HI GSPFK V Sbjct: 2194 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2471 HSP 3 Score: 83.9593 bits (206), Expect = 1.746e-14 Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD R CS+V++ + + + +S ++ +L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089 HSP 4 Score: 81.6481 bits (200), Expect = 8.270e-14 Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK + ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V +P + E + + N KP + F V EI V P G ++ I NKDG + V +A T +G++ + ++G I S PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911 HSP 5 Score: 72.7886 bits (177), Expect = 3.919e-11 Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + VK I + S+ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1995 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2286 HSP 6 Score: 71.2478 bits (173), Expect = 1.292e-10 Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L G V V S PG L + + +KAE+S + K G Y V+Y G Y + + +PH P R+ V A D +R ++ ++ D+ E +S + VG + I H+++P + CFVT+ N DG Y +++ F L ++ D D+ I N + V E Q + A G GL++A N+ N F + L +T++GPS+ +I+C ++ +G YIP G Y + ITY HIPGSPF++ V Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415 HSP 7 Score: 70.0922 bits (170), Expect = 2.777e-10 Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +F P G + I I + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I Sbjct: 512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636 HSP 8 Score: 67.781 bits (164), Expect = 1.303e-9 Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276 + I N PF+V V + + + GPGL + + P VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ + + V + KVK+ G+ + +SF +DS + P +V G+ +V + + P + V V Y ++ P+ + YD+++ S++ ++ +DA + L V + + K+ I+ H+ + + T+ I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ ++ T V + +P+ Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717 HSP 9 Score: 62.3882 bits (150), Expect = 6.220e-8 Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L + F N N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420 HSP 10 Score: 62.003 bits (149), Expect = 8.705e-8 Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I ++ Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1913 HSP 11 Score: 58.9214 bits (141), Expect = 7.544e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 12 Score: 56.6102 bits (135), Expect = 2.943e-6 Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I +SPY + ++ + D+ +++ V+ L+ K Sbjct: 2099 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2301
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|Q80X90|FLNB_MOUSE (Filamin-B OS=Mus musculus OX=10090 GN=Flnb PE=1 SV=3) HSP 1 Score: 163.696 bits (413), Expect = 1.178e-38 Identity = 135/502 (26.89%), Postives = 227/502 (45.22%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532 KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ D+ K L W+ +K+ I N + W G A+G +V++C LC D W+ ++NA+ AM+ A +PQ++ P EII + ++MTY+SQF L+ + N K + I+ GN A + D IS G+ D+++ + E + + V DKN S +P ++G + + I PF V V+ + + + GPGL G++A+ P F + T G+ IG +E P K +E + GN Y + PG + + + + I SP+ + I ++ + + ++ G+ + T F +D++ + Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMVFVEDPEGNKEEARVTPDSDKN---------------KTYSVEYLPKVTGLHKVIVLFA--GQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAA 482 HSP 2 Score: 98.5969 bits (244), Expect = 6.343e-19 Identity = 94/321 (29.28%), Postives = 139/321 (43.30%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV-ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D K G VSY PG Y +I FN IP SP+ + V A + R L + + +Q G + +P + + + +I + V P G + ++ FI G++ ID +G +KV++ Q NP +V+ AYG GL+ T ++ FFI N +++ +L VTI+GPSKV++ C E GY Y P+ G Y IG+ Y HI SPFK V Sbjct: 2194 HKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCL---------TVLSLQESGLKVN-QPASFAIRLNGAKGKI---DAKVHSPSGAVEECHVSELEPDKYAVRFI---PHENGIHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGAGLETGTTGIQSEFFI---NTTQA---GPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKV 2471 HSP 3 Score: 85.5001 bits (210), Expect = 6.005e-15 Identity = 79/319 (24.76%), Postives = 135/319 (42.32%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G N F + T G L + IEGPSKAEIS +D K G V+Y T+PG+Y + +N IP SPF + DD NRR CS+V++ + + + +S ++ L + P G +K++ IG+ +F+ ++G V I+ + ++ +S I ++ I + + YG GL + + F + ++ + + ++GPSKV I + +G Y P V G+Y + ++++ H+PGSPF + + Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDD-NRR----------CSQVKLGS----------AADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGQGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089 HSP 4 Score: 81.6481 bits (200), Expect = 8.698e-14 Identity = 88/317 (27.76%), Postives = 129/317 (40.69%), Query Frame = 3 Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV T+GK I ++AE ++ + G Y + Y PG YV + F VDIP+SPF + D + V +P + E + + N KP + F V EI V P G + I NKDG + V + P+ +V + +H R + + +PL Y N + AYG GL N+ F I + E LD+ I+GPSK +ISCI++ +G Y+P + G Y I + Y++K HIPGSPF + D Sbjct: 1636 FVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGT---VHMPSGKKATPEI-----VDNKDGTVTV------------------RYAPT-EVGLHEMHIKYRGSHIP-------ESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911 HSP 5 Score: 72.7886 bits (177), Expect = 4.053e-11 Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI--VKSNKVDEIKKVKVIGLENK-----NTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQR 1745 SF P G + + + + I PF V V + ++GPGL+G + F++++ GS+ +GF++EGPS+ KIE + +GS + Y PG Y + IM ++E+I DSPY I + ++ + GLE N FI+D +++ P + D G + + + ++ Y PL + I V + V + PY ++ + Q+ Sbjct: 512 SFEYYPSTPGKYSVAVTWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAG-SAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVV-WGGVNIPHSPYRVNIGQGSHPQK 744 HSP 6 Score: 71.2478 bits (173), Expect = 1.178e-10 Identity = 84/342 (24.56%), Postives = 145/342 (42.40%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V G+ L +G + F+V T G +++ +EGPSK +I D + G VSY T+PG Y+ + F +P SPF + ++ + R + + ++ VG ++ PEI +++ VT P G + I M K S+ F+ +GV+ + S K + +++ GS T + PL ++ + A G GL++ F I W L + ++GPSK +I+ + NG YI G Y + I ++++ HIP SP+ + V+ P+ D Sbjct: 1995 VQSEIGDARR----AKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVR-------------ESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGIPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPDSPYLVPVIA-PSDD 2286 HSP 7 Score: 65.855 bits (159), Expect = 5.720e-9 Identity = 37/93 (39.78%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P VH G L + F N +N F V T G G L I +EGPS+++I+ D K G Y PG+Y I++ V IP SPFR+ D V+ Sbjct: 1328 PSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVD 1420 HSP 8 Score: 63.929 bits (154), Expect = 2.034e-8 Identity = 40/137 (29.20%), Postives = 68/137 (49.64%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K ++ P G ++ IK I P + VN PN ++ +YGPGL VA+ F I+ + + + ++EGPSK +I C + +G+ +TY LPG Y + + N+++I SP++ I N+ Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKYR--GSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNR 1913 HSP 9 Score: 60.077 bits (144), Expect = 2.729e-7 Identity = 92/415 (22.17%), Postives = 161/415 (38.80%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKN------TKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIE--LSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237 + I N PF+V V + + + GPGL + + VF + T G+ +G ++EGPS++KI C + +GS Y PG Y ++I +I SP+ V S V + KVK+ G + +SF +DS + P +V G+ +V + + P IV V Y ++ P+ + YD+++ S + +E D DA E L+VQ + + K + T +++ T+ +I K G + G + G R + G+ C + +++ G +GFV++ E + +DG Y I + G Y ++V G I SPF++ ++ Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGP-YIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVE-FAIDARDAGEGLLAVQ----------ITDQEGKP---QRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD 1706 HSP 10 Score: 59.3066 bits (142), Expect = 4.956e-7 Identity = 36/120 (30.00%), Postives = 62/120 (51.67%), Query Frame = 3 Query: 1068 LIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 IP G F + + + + + P+ V +LP + ++GPGL G + P F +DT G+ +EGP + KIEC++ G+G+ ++Y PG Y ++I+ E +I SP+ Sbjct: 1006 FIPREEGLFAVDVTYDGHP--VPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123 HSP 11 Score: 55.8398 bits (133), Expect = 5.480e-6 Identity = 55/212 (25.94%), Postives = 95/212 (44.81%), Query Frame = 3 Query: 882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 I + + P V G + DL +KIP I + ++ +G+V + S+ + F +P G + +K + PF+ V + + + GPGL A P F I + ++EGPSK +I + NGS ++Y A PG Y++SI N+E+I DSPY + ++ + D+ + + V+ L+ K Sbjct: 2099 ITRTSRAPAVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPS--DDARCLTVLSLQESGLK 2301
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|Q8BTM8|FLNA_MOUSE (Filamin-A OS=Mus musculus OX=10090 GN=Flna PE=1 SV=5) HSP 1 Score: 158.688 bits (400), Expect = 3.113e-37 Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 ++ EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S +NNA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ ++ ++ P+ K + G+ + +Y + G++ + + I SPY++ + ++ Sbjct: 23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477 HSP 2 Score: 106.301 bits (264), Expect = 2.669e-21 Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + V +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + G+Y ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2239 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 80.8777 bits (198), Expect = 1.284e-13 Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + S T NKDG + V S G++ +D ++ +N+H + + L VD VN +I AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y+++ HIPGSPF V D + ++H Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1962 HSP 4 Score: 76.2554 bits (186), Expect = 3.550e-12 Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ + ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + DT + D T +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.707 bits (169), Expect = 3.611e-10 Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ +G + + PE I ++ VT P G + H ++ + N I + +G++ + S K K +++ GS T + PL ++ + A G GL++A V F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331 HSP 6 Score: 68.5514 bits (166), Expect = 7.013e-10 Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N IP SPF V D + R+ H V Sbjct: 1872 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1965 HSP 7 Score: 67.0106 bits (162), Expect = 2.412e-9 Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583 F P + G++ + I I PF V V + ++GPGL G + F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I ++ + +VK GLE F +D++++ + P V+ D G S Sbjct: 539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718 HSP 8 Score: 59.6918 bits (143), Expect = 4.232e-7 Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N I +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + N+++I SP++ + Sbjct: 1824 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1952 HSP 9 Score: 58.9214 bits (141), Expect = 6.229e-7 Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK + ++ P DV G+ + V +K F ++C L+V V Sbjct: 2386 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2594
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|P21333|FLNA_HUMAN (Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4) HSP 1 Score: 158.303 bits (399), Expect = 5.203e-37 Identity = 136/514 (26.46%), Postives = 232/514 (45.14%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-------QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + EM T+ ++ + KI++ FTRW N LK +K I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + DE K L W+ +KL I N S W SG A+G +V++C LC D W++S + NA+ AM+ A IPQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN A + + S G+ ++L+ + D G+ + N K+ S +P ++G+ + + I PF V V+ + + + GPGL G++A+ F + T G+ Q +G + ++E G+ + +Y + G++ + + I SPY++ + ++ + V GL+ K + Sbjct: 23 TRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEAR--GDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGR-GLQPKGVR 496 HSP 2 Score: 106.301 bits (264), Expect = 2.538e-21 Identity = 100/326 (30.67%), Postives = 141/326 (43.25%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + +F + T G LAI +EGPSKAEISF D+K G V+Y V PG+Y ++ FN+ IP SPF + VA RR+ ++ S +++ + + S+ + V SP C+VTE ++D + + GVY ID F G I G +K+++ E HG +P +V+ AYG GL+ F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2239 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGVYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGNPAEFVVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 79.7221 bits (195), Expect = 3.610e-13 Identity = 83/327 (25.38%), Postives = 141/327 (43.12%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C S+ ++ ++ + G + + Y PG+YV + F +P+SPF++T +A D V + + + P Q N + TS++P + F + EI V P G + + + T NKDG + V S G++ +D ++ +N+H + + L VD Y N + AYG GL VN+ F + N ++ E L + I+GPSK +ISC ++ +G Y+P++ G Y I + Y N+ H+PGSPF V D + ++H Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPTITDNKDGTVTVRYAPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVD------------YVNCGHVTAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKY-NEQHVPGSPFTARVTGDDSMRMSH 1962 HSP 4 Score: 78.1814 bits (191), Expect = 9.410e-13 Identity = 99/456 (21.71%), Postives = 176/456 (38.60%), Query Frame = 3 Query: 993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLI-IKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249 V +G C N + +P G +++ + + + + PF + P K + ++GPGL G A P F +DT G+ +EGP + ++EC + G+G+ ++Y PG Y ++I+ + +I SP+ +V ++ K GLE F +D S + E+ +E + G+ + + + + PL V + Y V FP A+D Y EGQ + +T S+ + L V A + + + V R + +++ +EE +D + +S P+ +G C ++ + IQ G+ F +E GP E ++ C DG +++ P AG Y L VT G + GSPF + V + +D Sbjct: 1009 VGPSGAAVPCKVEPGLGADNSV-VRFLPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPS----GNLTETYVQDRGDGMYKVEYTPYEEG----LHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448 HSP 5 Score: 69.3218 bits (168), Expect = 4.846e-10 Identity = 39/98 (39.80%), Postives = 51/98 (52.04%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210 V G L G VN F V+T G L++ IEGPSKAEIS D + G VSY +PG+Y + +N+ +P SPF V D + R+ H V Sbjct: 1868 VTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKV 1965 HSP 6 Score: 69.3218 bits (168), Expect = 5.139e-10 Identity = 90/345 (26.09%), Postives = 145/345 (42.03%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E GD S+ V V G+ L +G +F++ T G L++ IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + V I + P S+ VG + + PE I ++ VT P G + H ++ + N I + +G + + S K K +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +IS + +G C + V+ G Y + + + N+ HIP SPF + V P+ D Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGTHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331 HSP 7 Score: 65.855 bits (159), Expect = 5.225e-9 Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNS 1532 F P++ G++ + I I PF V V + ++GPGL G V F+++ G D +GFS+EGPS+ KIEC + G+GS + Y G Y + ++ N E+I SP+ I + + +VK GLE F +D+++ Sbjct: 539 GFEYYPMVPGTYIVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHG 702 HSP 8 Score: 60.8474 bits (146), Expect = 1.557e-7 Identity = 35/132 (26.52%), Postives = 70/132 (53.03%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P +G ++ I+ + +M I P + V+ N + +YGPGL V + P F ++T + + + ++EGPSK +I C + +G+ ++Y +LPG Y + + NE+++ SP++ + Sbjct: 1824 KDGTVTVRYAPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARV 1952 HSP 9 Score: 56.9954 bits (136), Expect = 2.450e-6 Identity = 58/218 (26.61%), Postives = 94/218 (43.12%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673 ++ + IP +G + I +K N I PF++ V P P +VS YG GL G V P F+++T N + +++GPSK K++C G +TY+ + PG Y +SI +I SP+ + V ++ + E V V L TK+ + P D G+ + V +K F ++C L+V V Sbjct: 2386 DKYAVRFIPRENGVYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVG--QKSSFTVDCSKAGNNMLLVGV 2594
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|D3ZHA0|FLNC_RAT (Filamin-C OS=Rattus norvegicus OX=10116 GN=Flnc PE=1 SV=1) HSP 1 Score: 156.762 bits (395), Expect = 1.262e-36 Identity = 131/498 (26.31%), Postives = 229/498 (45.98%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLV-VEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDI---FIKKNEYSMEILNKPFRVCVNL----PNKKPTIVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 +++ EM T+ ++ + KI++ FTRW N LK K + DLQ DL +G L+ L+E+LSQK++ K RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE + L W+ +K+ I N + W G A+G +V+ C LC D W+ + + NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF + + ++ N K + I+ GNT + A + + T++ + + LV +E D G+ + N K + S +P ++G + F +N I PF V V + NK + + GPGL G+VA+ P F + T G+ + + P + +E A + G+ + TY ++ G + + + I SP+ + + ++ Sbjct: 17 DEADEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAI---AYGPGIEPQGNTVLQPAHFT-----------------------------VQTVDAGVGEVLVYIE--DPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN-----IERSPFEVNVGMALGDANK---VSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEA 472 HSP 2 Score: 113.62 bits (283), Expect = 1.512e-23 Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQ-NKGNSTSIKPVGKNLIF--HVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + VA D RR+ ++ E ++ N+ S +++ G + V +P C+V+E S H I+ + + GV++ID F G I G +K+++ Q +P +V+ AYG GL+ T + F + N +L VTIDGPSKVQ+ C E G++ Y P+ G Y I I Y HI GSPFK V Sbjct: 2316 HKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQ-----ETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD--SDKHTIRFIPHEN-------------GVHSIDV-KFNGAHIPGSPFKIRVGE--------------QSQAGDPGLVS-------AYGPGLEGGTTGVSSEFIVNTQNAGSG------ALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKV 2593 HSP 3 Score: 85.5001 bits (210), Expect = 6.257e-15 Identity = 86/329 (26.14%), Postives = 128/329 (38.91%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNKDG--FINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN F + T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF + D + R N G ST + ++ ++ L + P G +K++ S T + G ++V S V N F +G +IG + KV++ +G GL + + F + N L ++I+GPSKV I+C + +G Y P G Y I I +++K H+PGSPF + V Sbjct: 1863 VSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMR-------------TSQLNVGTSTDVS-------LKITEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRV-----------------------------------WGKGLSEGQTFQVAEFIVDTRNAGYG------GLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADK-HVPGSPFTVKV 2129 HSP 4 Score: 70.0922 bits (170), Expect = 2.816e-10 Identity = 51/165 (30.91%), Postives = 82/165 (49.70%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL----YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRNS 1532 P++ G + + I Y+ I PF V V+ + ++GPGL G AD F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I + KVK G + T F ID+R + Sbjct: 540 PVIPGKYVVTITWGGYA--IPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSAD----FVVEAIGTEVGTLGFSIEGPSQAKIECDDRGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAA 698 HSP 5 Score: 65.855 bits (159), Expect = 4.861e-9 Identity = 40/133 (30.08%), Postives = 64/133 (48.12%), Query Frame = 3 Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 S + + +P G + + I + + + PF V LP + +YGPGL G + P F +DT G+ +EGP + KIEC + G+GS ++Y PG Y ++I+ E +I SP+ I Sbjct: 1020 SGAEAQAVRYMPPEEGPYKVDITYDGHP--VPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATI 1150 HSP 6 Score: 61.2326 bits (147), Expect = 1.255e-7 Identity = 40/93 (43.01%), Postives = 49/93 (52.69%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L G VN N+F V T G G L + IEGPS+A++S D K G V Y PG+Y I+F IP SPFR+ V D V+ Sbjct: 1351 PTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYVPFTPGDYDVNITFGGQPIPGSPFRVPVKDVVD 1443 HSP 7 Score: 58.151 bits (139), Expect = 1.183e-6 Identity = 40/118 (33.90%), Postives = 57/118 (48.31%), Query Frame = 3 Query: 4881 TESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228 +E GD S+ V V GK L +G +F+V T G L + IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + + I + P I + Sbjct: 2037 SEIGDASK----VRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIAT 2150
BLAST of Filamin A vs. TrEMBL
Match: A0A5K3FEG0 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 198.749 bits (504), Expect = 6.185e-47 Identity = 187/759 (24.64%), Postives = 304/759 (40.05%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGEN---NFDEIGKS----FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE-----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDK------LGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243 I+K FTRW N LK + D+QFD +G L++LIE LS +K + R ++ + VL FL EG+ L NI+ DI+D K I L+W LI HYSI L E N G + L+WLNSKL + N ++ WN G AIG +V+ C LC D +W L NA AM AA Q +PQL+ P E+I+ +KA+MTY+SQF L+ R N + + ++ GN M A + D S G V++++ ++ G C N + N S + +P +G + + IK + EI+N PF+V V + + GPG+ VADC ILD G I P+ T+ N L+ Y+ + G++ +++ + I +SP+ +++ +++ + ++ L++ S I N ++ PP C K G+ + V +L F V E ++ EG + + +EKC Q + CV T +T + H ++ + K+ + +G L G + K VV+ + + G++GF +EGP E ++ C DG + + P G+Y + + + ++I SP+ + + S Sbjct: 46 IQKNTFTRWANEHLKTKGTSVDDIQFDFADGLRLIDLIESLSGQKFRHVNRKPSFRTQKLENVTMVLRFLEEQEGLRLVNIDSTDIVDCRTKLILGLIWTLILHYSITLPLWEGEDYNQGSTGPTPKQRLLSWLNSKLMERPVKNFTTDWNDGTAIGALVDACAPGLCPDWREWEPKQKLRNATEAMRAAEQWLEVPQLIHPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRAN---PASVRAYGPGLEPKGNKVGMPARFTIDASS-------------AGKGSVEVIV-----------------LNPKGQREPCDIVPNTDRPNTYSCAYVPTQAGEYRVIIKF--ATKEIMNSPFKVMVEGAADPSKVTASGPGIEPQGNQVGRRTFFNIFTAGAGEGVADC---VILDPQGRQDVI-----KPNITRQSEDNY-----LVEYTPRMEGLHSVNVFFAGQQIPNSPFGVMVGPQAPIEQGGSKPLNANRIPALKSDQPISPIKRPDNQSY-APPRPACDAKQAYATGRGIQPQGVRVRDLAD---------------------FKVHTE---------EAGEGVLEATVVGP-TGREEKC----QQRKIGPYTYE----CVYTPQQPGPHTVNVRYGGDHIMLSPFKVDVGPY--KETRIRAFGPGLVGGIVNKPAVFVVETNGET----GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADS 710 HSP 2 Score: 100.523 bits (249), Expect = 5.326e-17 Identity = 57/156 (36.54%), Postives = 86/156 (55.13%), Query Frame = 3 Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577 I+ PF+V V P K+ I ++GPGL G + + P VF+++TNG +GFS+EGPS+ +I+CA+ G+GS + Y +PG Y + I+ NEENI SPY + I + + VK G+ F ID+R++ P E D+ G Sbjct: 605 HIMLSPFKVDVG-PYKETRIRAFGPGLVGGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADSGKCDPNAVKCYGPGLSPGVVAGIPTEFTIDARDAGGPAPFACELRDEAG 759 HSP 3 Score: 95.1301 bits (235), Expect = 2.137e-15 Identity = 43/88 (48.86%), Postives = 61/88 (69.32%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVAD 5177 +V V+G+ + +G+ N NN+F ++T GNL+I IEGPSKAEI F D+K G +VS+RV+ PGEY C+I FN + SPFR+ + D Sbjct: 2095 KVRVLGQGIQRGYANCNNEFSIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCVVSFRVSEPGEYFCSIRFNDEHVQGSPFRLDIED 2182 HSP 4 Score: 88.5817 bits (218), Expect = 2.089e-13 Identity = 86/337 (25.52%), Postives = 146/337 (43.32%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-SKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870 ++E G+ S+ V V G+ L +G N N +F V TS G L++ IEGPSKA+I D + G +V+YR T PG Y+ + + ++P SPF + + + R++ + + +E ++K G N + ++ VT P G H K M S+ + + I GV+ + V+ N+H GS T + P I + + G G+Q+ N N F I+ +L + I+GPSK +I + +G C + + G YF I ++++ H+ GSPF++ + Sbjct: 1894 ESELGNASR----VRVYGRGLHEGTANQNCQFTVDTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGHPSARVMERITRQREVAEATQVGSQCELNLKIPGVN---------VREMSAVVTSPSG----HTEKCMVSELDHANYCIRFVPQETGVHTV--------------SVRHRNLHIPGSPFQFT---------VGP-ITDGGANKVRVLGQGIQRGYANCNNEFSIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CVVSFRVSEPGEYFCSIRFNDE-HVQGSPFRLDI 2180 HSP 5 Score: 85.5001 bits (210), Expect = 1.653e-12 Identity = 87/335 (25.97%), Postives = 135/335 (40.30%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888 V G L G +F + T G L+I +EGPSKAEI D K G SY PGEY +I F I SPF + +D R V SEV ++ +S +I NL VT P G IK++ S T + D +NV+ + + N F F+G+ ++G + +V++ YG GL + T N+ F + ++ L ++I+GPSK I C ++ +G + Y P G Y I + Y+++ ++PGSPF + + P++ Sbjct: 1722 VTAYGPGLSHGRAGEPAEFTLVTREAGAGGLSIAVEGPSKAEIVCRDNKNGTCSASYLPLAPGEYTISIKFMDQHIQGSPFIANIMEDPLRM---TQVMVGTTSEVPLR------------------ISETDIYNLTATVTNPSGIEQPSMIKRLPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNASRVRV-----------------------------------YGRGLHEGTANQNCQFTV------DTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGHPSA 1993 HSP 6 Score: 79.7221 bits (195), Expect = 1.070e-10 Identity = 90/344 (26.16%), Postives = 138/344 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICI--EGPSKAEISFMDKKIGIYIVSYRVTIPG-EYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV--------SSPEILNLNCFVTEPHGGSSFHPIKKMSK-TSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSC------DVDIQIINPLIVNEIYQN----ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P V V G + N F+V PGN+ I + E + D + G + V+Y G Y + F ++P SPF++ V +V+ +H P S PVGK F V SSP+ N V P+G ++ S+ T DG+ F T+ GP +V ++ +R + C D I + Q+ + AYGDGL++AT N HF I +S L VTI+GP++ QI+ ++ +G Y+P+ G Y + + Y +K H+PGSPF + V Sbjct: 812 PGNVRVYGPGVESITRNEPTYFIVDCKQAGPGNVGISVRDEAGRDVPMDTKDMRDGTFKVAYTPMTAGPTYTVQVYFENTEVPRSPFKVPVKPNVDMSKVHVDGLP---------------STIPVGKPTTFDVVTAGAGPPSSPKP-RPNVIVKAPNG------MRVPSQLTETPDGYEATFTPTMP--------------GPH-QVAVDVAGAPVRGSPFPCNAVPIQDAPIAAVKKPATFAAQQDPSGLVHAYGDGLRKATANVPAHFTI------DSREAPPAPLSVTIEGPAEAQINYTDNGDGTCGVDYLPVEPGPYTVNVLYKDK-HVPGSPFPVQV 1111 HSP 7 Score: 73.9442 bits (180), Expect = 4.942e-9 Identity = 40/93 (43.01%), Postives = 52/93 (55.91%), Query Frame = 3 Query: 5604 AYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882 A GDGL + V ++ FF+ N SL VT+DGPSKVQ++C E ++GY F Y P G Y I +TY + HI SPF+ V DP Sbjct: 2292 ANGDGLNRGVVGERSRFFVNTANAGSG------SLSVTVDGPSKVQLNCNERLDGYEFSYTPYAPGQYNISVTYDGQ-HIHHSPFRAYVTGDP 2377
BLAST of Filamin A vs. TrEMBL
Match: A0A5K3FF65 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 198.749 bits (504), Expect = 7.350e-47 Identity = 187/759 (24.64%), Postives = 304/759 (40.05%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGEN---NFDEIGKS----FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE-----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDK------LGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243 I+K FTRW N LK + D+QFD +G L++LIE LS +K + R ++ + VL FL EG+ L NI+ DI+D K I L+W LI HYSI L E N G + L+WLNSKL + N ++ WN G AIG +V+ C LC D +W L NA AM AA Q +PQL+ P E+I+ +KA+MTY+SQF L+ R N + + ++ GN M A + D S G V++++ ++ G C N + N S + +P +G + + IK + EI+N PF+V V + + GPG+ VADC ILD G I P+ T+ N L+ Y+ + G++ +++ + I +SP+ +++ +++ + ++ L++ S I N ++ PP C K G+ + V +L F V E ++ EG + + +EKC Q + CV T +T + H ++ + K+ + +G L G + K VV+ + + G++GF +EGP E ++ C DG + + P G+Y + + + ++I SP+ + + S Sbjct: 46 IQKNTFTRWANEHLKTKGTSVDDIQFDFADGLRLIDLIESLSGQKFRHVNRKPSFRTQKLENVTMVLRFLEEQEGLRLVNIDSTDIVDCRTKLILGLIWTLILHYSITLPLWEGEDYNQGSTGPTPKQRLLSWLNSKLMERPVKNFTTDWNDGTAIGALVDACAPGLCPDWREWEPKQKLRNATEAMRAAEQWLEVPQLIHPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRAN---PASVRAYGPGLEPKGNKVGMPARFTIDASS-------------AGKGSVEVIV-----------------LNPKGQREPCDIVPNTDRPNTYSCAYVPTQAGEYRVIIKF--ATKEIMNSPFKVMVEGAADPSKVTASGPGIEPQGNQVGRRTFFNIFTAGAGEGVADC---VILDPQGRQDVI-----KPNITRQSEDNY-----LVEYTPRMEGLHSVNVFFAGQQIPNSPFGVMVGPQAPIEQGGSKPLNANRIPALKSDQPISPIKRPDNQSY-APPRPACDAKQAYATGRGIQPQGVRVRDLAD---------------------FKVHTE---------EAGEGVLEATVVGP-TGREEKC----QQRKIGPYTYE----CVYTPQQPGPHTVNVRYGGDHIMLSPFKVDVGPY--KETRIRAFGPGLVGGIVNKPAVFVVETNGET----GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADS 710 HSP 2 Score: 138.272 bits (347), Expect = 1.593e-28 Identity = 103/333 (30.93%), Postives = 158/333 (47.45%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN-LNCFVTEPHGGSS---FHPIK------KMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882 +V V+G+ + +G+ N NN+F ++T GNL+I IEGPSKAEI F D+K G +VS+RV+ PGEY C+I FN + SPFR+ + +D +H + + + +Q++G +G + F V+ + L +V P G P+ + + N ++V + F +G + + N G R +++P Q+I A G GL V ++ FF+ N SL VT+DGPSKVQ++C E ++GY F Y P G Y I +TY + HI SPF+ V DP Sbjct: 2095 KVRVLGQGIQRGYANCNNEFSIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCVVSFRVSEPGEYFCSIRFNDEHVQGSPFRLDI-EDTGGYYASEHRQLSVAA---VQDRGLQ-----IGVPMAFTVNYTGVRGRLRAYVVTPSGKEEPAVVLPVDIDQHAVRFTPQENGPHLVHVLLDDRPIPGSPFRVLVGQEDFCEPGLVRANGDGLNRG----------VVDP-------QSIVASGAGLTSGAVGERSRFFVNTANAGSG------SLSVTVDGPSKVQLNCNERLDGYEFSYTPYAPGQYNISVTYDGQ-HIHHSPFRAYVTGDP 2394 HSP 3 Score: 100.138 bits (248), Expect = 5.657e-17 Identity = 57/156 (36.54%), Postives = 86/156 (55.13%), Query Frame = 3 Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577 I+ PF+V V P K+ I ++GPGL G + + P VF+++TNG +GFS+EGPS+ +I+CA+ G+GS + Y +PG Y + I+ NEENI SPY + I + + VK G+ F ID+R++ P E D+ G Sbjct: 605 HIMLSPFKVDVG-PYKETRIRAFGPGLVGGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADSGKCDPNAVKCYGPGLSPGVVAGIPTEFTIDARDAGGPAPFACELRDEAG 759 HSP 4 Score: 88.5817 bits (218), Expect = 2.127e-13 Identity = 86/337 (25.52%), Postives = 146/337 (43.32%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-SKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870 ++E G+ S+ V V G+ L +G N N +F V TS G L++ IEGPSKA+I D + G +V+YR T PG Y+ + + ++P SPF + + + R++ + + +E ++K G N + ++ VT P G H K M S+ + + I GV+ + V+ N+H GS T + P I + + G G+Q+ N N F I+ +L + I+GPSK +I + +G C + + G YF I ++++ H+ GSPF++ + Sbjct: 1894 ESELGNASR----VRVYGRGLHEGTANQNCQFTVDTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGHPSARVMERITRQREVAEATQVGSQCELNLKIPGVN---------VREMSAVVTSPSG----HTEKCMVSELDHANYCIRFVPQETGVHTV--------------SVRHRNLHIPGSPFQFT---------VGP-ITDGGANKVRVLGQGIQRGYANCNNEFSIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CVVSFRVSEPGEYFCSIRFNDE-HVQGSPFRLDI 2180 HSP 5 Score: 85.5001 bits (210), Expect = 1.697e-12 Identity = 87/335 (25.97%), Postives = 135/335 (40.30%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888 V G L G +F + T G L+I +EGPSKAEI D K G SY PGEY +I F I SPF + +D R V SEV ++ +S +I NL VT P G IK++ S T + D +NV+ + + N F F+G+ ++G + +V++ YG GL + T N+ F + ++ L ++I+GPSK I C ++ +G + Y P G Y I + Y+++ ++PGSPF + + P++ Sbjct: 1722 VTAYGPGLSHGRAGEPAEFTLVTREAGAGGLSIAVEGPSKAEIVCRDNKNGTCSASYLPLAPGEYTISIKFMDQHIQGSPFIANIMEDPLRM---TQVMVGTTSEVPLR------------------ISETDIYNLTATVTNPSGIEQPSMIKRLPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNASRVRV-----------------------------------YGRGLHEGTANQNCQFTV------DTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGHPSA 1993 HSP 6 Score: 79.7221 bits (195), Expect = 1.089e-10 Identity = 90/344 (26.16%), Postives = 138/344 (40.12%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICI--EGPSKAEISFMDKKIGIYIVSYRVTIPG-EYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV--------SSPEILNLNCFVTEPHGGSSFHPIKKMSK-TSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSC------DVDIQIINPLIVNEIYQN----ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P V V G + N F+V PGN+ I + E + D + G + V+Y G Y + F ++P SPF++ V +V+ +H P S PVGK F V SSP+ N V P+G ++ S+ T DG+ F T+ GP +V ++ +R + C D I + Q+ + AYGDGL++AT N HF I +S L VTI+GP++ QI+ ++ +G Y+P+ G Y + + Y +K H+PGSPF + V Sbjct: 812 PGNVRVYGPGVESITRNEPTYFIVDCKQAGPGNVGISVRDEAGRDVPMDTKDMRDGTFKVAYTPMTAGPTYTVQVYFENTEVPRSPFKVPVKPNVDMSKVHVDGLP---------------STIPVGKPTTFDVVTAGAGPPSSPKP-RPNVIVKAPNG------MRVPSQLTETPDGYEATFTPTMP--------------GPH-QVAVDVAGAPVRGSPFPCNAVPIQDAPIAAVKKPATFAAQQDPSGLVHAYGDGLRKATANVPAHFTI------DSREAPPAPLSVTIEGPAEAQINYTDNGDGTCGVDYLPVEPGPYTVNVLYKDK-HVPGSPFPVQV 1111
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3P3Q8 (Filamin-A OS=Schistocephalus solidus OX=70667 GN=FLNA PE=4 SV=1) HSP 1 Score: 197.208 bits (500), Expect = 1.783e-46 Identity = 203/771 (26.33%), Postives = 313/771 (40.60%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVK-----------SNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNA---ERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDV---LVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTG 2252 I+K FTRW N LK + + DLQFDL +G L+EL+E LS +K R N+ R L +V + LR EG+ L NI+ DI+D +K I L+W LI HYSI L E D G + L WLNSKL + N ++ WN G AIG +V++C LC D W L NAQ AM AA Q +PQL++P E+I+ +KA+MTY+SQF L+ R N + + ++ GN M A + D S G V++++ ++ G C N + N S + +P SG + + IK + EI+N PF+V V + GPG+ VADC ILD G I P T+ N L+ Y+ + G++ +++ + I +SP+ +++ +NK E K + + K + + +PP VS ++ + ++ C A R I G + + F + D+ EG + + +EKC Q V A CV T LVN R I F +++ + D + + +G L + K VV+ + + G SI EGP E ++ C DG + + P G+Y + + + ++I SP+ + +S +DTG Sbjct: 40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI-----KPVITRQSEDNY-----LVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMVGPRIQDAPPLTPLANKPIEATKTPIQQAGPRAAKPW------NAQPVPPSEPL-----VSPRAAPRSDQMRAPWKTACDPKQAYATGRGIQPQGVRVRDLADF--KVHTEDAGEGVLEATVVGP-NGREEKC----QQRKVGAYLHE----CVYTPQQPGPHLVNVRYGGDHIMLSPF---KVEVGPYKDTR--IRAFGPGLVSGIVNKPAVFVVETNGETGALGFSI----EGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPIS--ADTG 726 HSP 2 Score: 98.5969 bits (244), Expect = 1.964e-16 Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3 Query: 954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577 + + A V+EA V NG KC + + +E ++ P G + ++ I+ PF+V V P K I ++GPGL + + P VF+++TNG +GFS+EGPS+ +I+CA+ G+GS + Y +PG Y + I+ N+ENI SPY + I + +VK G+ F +D+R + P V+ D +G Sbjct: 564 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 774 HSP 3 Score: 95.5153 bits (236), Expect = 1.663e-15 Identity = 47/112 (41.96%), Postives = 69/112 (61.61%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQN 5246 ++V +G L G++ NN+F ++T GNL+I IEGPSKAEI F D+K G VS+RVT PGEY+C+I FN +P SPFR+ + D + ++ K + V+ +N Sbjct: 2112 HKVRAMGPGLQHGYIYANNEFNIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCCVSFRVTEPGEYLCSIRFNDEHVPGSPFRVDIEDTGSNQVYATETKQLSVAAVQDRN 2223 HSP 4 Score: 88.5817 bits (218), Expect = 1.798e-13 Identity = 84/326 (25.77%), Postives = 137/326 (42.02%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN---LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870 V V G+ L +G N N +F V T G L++ IEGPSKA+I D + G +V+YR T PG Y+ + + ++P SPF + + + ++ + + +E S+K G N L V+SP C ++EP + SN I +GV+ + ++ NIH GS T + P I + + A G GLQ + N F I+ +L + I+GPSK +I + +G C + + G Y I ++++ H+PGSPF++ + Sbjct: 1921 VRVYGRGLREGMANQNCQFTVDTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGQPSPLVMERITRQREVAEATHVGSQCELSLKIPGVNPRELTAVVTSPSGRTEQCVISEP-------------EPSNYS--IRFVPQELGVHTV--------------SIRHRNIHVPGSPFQFT---------VGP-ITDGGAHKVRAMGPGLQHGYIYANNEFNIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CCVSFRVTEPGEYLCSIRFNDE-HVPGSPFRVDI 2198 HSP 5 Score: 85.8853 bits (211), Expect = 1.182e-12 Identity = 87/334 (26.05%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPN 5885 V G L G +F + T G L+I +EGPSK+EI D K G SY PGEY AI F I SPF + +D R V SEV ++ +S +I NL VT P G IK+M S T + D +NV+ + + N F F+G+ ++G + +V++ YG GL++ N+ F + ++ L ++I+GPSK I C ++ +G + Y P G Y I + Y+++ ++PGSPF + + P+ Sbjct: 1740 VTAYGPGLSHGRTGEPAEFTLVTRDAGAGGLSIAVEGPSKSEIICRDNKNGTCSASYLPLAPGEYTIAIKFMDQHIQGSPFLARIVEDPRRM---TQVVVGTTSEVPLR------------------ISETDIYNLTASVTSPSGVEQPSVIKRMPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNAARVRV-----------------------------------YGRGLREGMANQNCQFTV------DTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGQPS 2010 HSP 6 Score: 73.9442 bits (180), Expect = 5.756e-9 Identity = 42/95 (44.21%), Postives = 55/95 (57.89%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882 + A GDGL + V KN FF+ N S++ +L VT+DGPSKVQ++C E +GY F Y P G Y I I Y ++ HI SPF+ V DP Sbjct: 2309 VFASGDGLSRGVVGEKNRFFV---NTSQA---GSGALSVTVDGPSKVQLNCSERPDGYEFTYTPYAPGNYTISIKYEDQ-HIVQSPFRAFVTGDP 2396
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3NX60 (Filamin-A (Fragment) OS=Schistocephalus solidus OX=70667 GN=FLNA PE=4 SV=1) HSP 1 Score: 189.889 bits (481), Expect = 2.826e-44 Identity = 142/482 (29.46%), Postives = 209/482 (43.36%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 I+K FTRW N LK + + DLQFDL +G L+EL+E LS +K R N+ R L +V + LR EG+ L NI+ DI+D +K I L+W LI HYSI L E D G + L WLNSKL + N ++ WN G AIG +V++C LC D W L NAQ AM AA Q +PQL++P E+I+ +KA+MTY+SQF L+ R N + + ++ GN M A + D S G V++++ ++ G C N + N S + +P SG + + IK + EI+N PF+V V + GPG+ VADC ILD G I K + L+ Y+ + G++ +++ + I +SP+ +++ Sbjct: 40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI----------KPVITRQSEDNYLVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMV 470 HSP 2 Score: 98.5969 bits (244), Expect = 1.874e-16 Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3 Query: 954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577 + + A V+EA V NG KC + + +E ++ P G + ++ I+ PF+V V P K I ++GPGL + + P VF+++TNG +GFS+EGPS+ +I+CA+ G+GS + Y +PG Y + I+ N+ENI SPY + I + +VK G+ F +D+R + P V+ D +G Sbjct: 581 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 791 HSP 3 Score: 63.1586 bits (152), Expect = 9.014e-6 Identity = 37/97 (38.14%), Postives = 49/97 (50.52%), Query Frame = 3 Query: 4908 PYE---VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNR 5189 PY+ + G L G VN FVV T+G+ G L IEGPS+A I D G V Y T+PGEY I N +IP SP+ + ++ D + Sbjct: 649 PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGET-GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGK 744
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3PDR0 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR102074 PE=4 SV=1) HSP 1 Score: 189.504 bits (480), Expect = 4.407e-44 Identity = 144/482 (29.88%), Postives = 211/482 (43.78%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 I+K FTRW N LK + + DLQFDL +G L+EL+E LS +K R N+ R L +V + LR EG+ L NI+ DI+D +K I L+W LI HYSI L E D G + L WLNSKL + N ++ WN G AIG +V++C LC D W L NAQ AM AA Q +PQL++P E+I+ +KA+MTY+SQF L+ R N + + ++ GN M A + D S G V++++ ++ G C N + N S + +P SG + + IK + EI+N PF+V V + GPG+ VADC ILD G I P T+ N L+ Y+ + G++ +++ + I +SP+ +++ Sbjct: 40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI-----KPVITRQSEDNY-----LVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMV 470 HSP 2 Score: 98.5969 bits (244), Expect = 1.839e-16 Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3 Query: 954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577 + + A V+EA V NG KC + + +E ++ P G + ++ I+ PF+V V P K I ++GPGL + + P VF+++TNG +GFS+EGPS+ +I+CA+ G+GS + Y +PG Y + I+ N+ENI SPY + I + +VK G+ F +D+R + P V+ D +G Sbjct: 581 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 791 HSP 3 Score: 95.5153 bits (236), Expect = 1.557e-15 Identity = 47/112 (41.96%), Postives = 69/112 (61.61%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQN 5246 ++V +G L G++ NN+F ++T GNL+I IEGPSKAEI F D+K G VS+RVT PGEY+C+I FN +P SPFR+ + D + ++ K + V+ +N Sbjct: 2129 HKVRAMGPGLQHGYIYANNEFNIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCCVSFRVTEPGEYLCSIRFNDEHVPGSPFRVDIEDTGSNQVYATETKQLSVAAVQDRN 2240 HSP 4 Score: 88.9669 bits (219), Expect = 1.698e-13 Identity = 84/326 (25.77%), Postives = 137/326 (42.02%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN---LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870 V V G+ L +G N N +F V T G L++ IEGPSKA+I D + G +V+YR T PG Y+ + + ++P SPF + + + ++ + + +E S+K G N L V+SP C ++EP + SN I +GV+ + ++ NIH GS T + P I + + A G GLQ + N F I+ +L + I+GPSK +I + +G C + + G Y I ++++ H+PGSPF++ + Sbjct: 1938 VRVYGRGLREGMANQNCQFTVDTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGQPSPLVMERITRQREVAEATHVGSQCELSLKIPGVNPRELTAVVTSPSGRTEQCVISEP-------------EPSNYS--IRFVPQELGVHTV--------------SIRHRNIHVPGSPFQFT---------VGP-ITDGGAHKVRAMGPGLQHGYIYANNEFNIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CCVSFRVTEPGEYLCSIRFNDE-HVPGSPFRVDI 2215 HSP 5 Score: 86.2705 bits (212), Expect = 1.126e-12 Identity = 87/334 (26.05%), Postives = 134/334 (40.12%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPN 5885 V G L G +F + T G L+I +EGPSK+EI D K G SY PGEY AI F I SPF + +D R V SEV ++ +S +I NL VT P G IK+M S T + D +NV+ + + N F F+G+ ++G + +V++ YG GL++ N+ F + ++ L ++I+GPSK I C ++ +G + Y P G Y I + Y+++ ++PGSPF + + P+ Sbjct: 1757 VTAYGPGLSHGRTGEPAEFTLVTRDAGAGGLSIAVEGPSKSEIICRDNKNGTCSASYLPLAPGEYTIAIKFMDQHIQGSPFLARIVEDPRRM---TQVVVGTTSEVPLR------------------ISETDIYNLTASVTSPSGVEQPSVIKRMPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNAARVRV-----------------------------------YGRGLREGMANQNCQFTV------DTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGQPS 2027 HSP 6 Score: 73.9442 bits (180), Expect = 5.618e-9 Identity = 42/95 (44.21%), Postives = 55/95 (57.89%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882 + A GDGL + V KN FF+ N S++ +L VT+DGPSKVQ++C E +GY F Y P G Y I I Y ++ HI SPF+ V DP Sbjct: 2326 VFASGDGLSRGVVGEKNRFFV---NTSQA---GSGALSVTVDGPSKVQLNCSERPDGYEFTYTPYAPGNYTISIKYEDQ-HIVQSPFRAFVTGDP 2413
BLAST of Filamin A vs. Ensembl Cavefish
Match: flnb (filamin B, beta (actin binding protein 278) [Source:ZFIN;Acc:ZDB-GENE-041026-1]) HSP 1 Score: 181.8 bits (460), Expect = 3.101e-45 Identity = 136/480 (28.33%), Postives = 225/480 (46.88%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNF-DEIGK-----SFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKI--PTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514 KI+K FTRW N L+ +K I DL+FDL +G L+ L+E+LS K++ K RQ ++ ++ L FL E ++L +I I+DG++K I L+W LI HYSI + E++ D + K L W+ SK+ I+N S W G A+G +V+ LC D W++ + N + AM+ A +PQ++ P EI+D ++++MTY+S F + T K + G + L + ++D+ + D K G +L + I P E + + +E + SF +P G + + I ++ + + KPF+V V I ++GPGL G F+++ G++ F++EGPS+ KIEC + +GS + + G Y + +M ++E I DSP+ + + KVKV G TK + Sbjct: 23 KIQKNTFTRWCNEHLRCMDKQINDLRFDLSDGLNLICLLEVLSHKRMFRKYHARPTLRQLKLDNVSVALEFLDHEKIKLVSISKA-IVDGNLKLILGLVWTLILHYSISIPVWEDDASDTVTKLTPEMRLLGWIQSKVPELPINNFSQDWQDGKALGALVDGL-APLCPDWESWDTVQRVTNTREAMQQADDWLGVPQVIAPEEILDPGVDEQSVMTYLSLFPKARLKPGAPLKPKTPKPKACRATGRGLQARGLRVV---QVADFKV-------DTHKAGPGNLAVHIIGPGNEVAVKQREALEGIS--------------------SFEYMPGDEGDYTVDIT---WANQHIPKPFKVHVGPKAGPQKIRAWGPGLEGGTVGMAASFLVEATGAES---FAIEGPSQAKIECDDQNDGSCFVRFWPSEAGEYAVHVMCDDEEIEDSPFMACVAPKKRGFRPAKVKVYGPGVSPTKVLV 464 HSP 2 Score: 70.8626 bits (172), Expect = 1.506e-11 Identity = 90/346 (26.01%), Postives = 140/346 (40.46%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY--NFLGDKIGPSW---------------KVKIE-------NIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P ++ G L G V F+V +G + IEGPS+A+I D+ G V + + GEY + + +I SPF VA + +P ++V++ G S + V F V + T+ G I+ + + K ++V G+YN + I SW KVKIE HGS R + DI +++PL + + AYG GLQ + ++ F I ++ L V I+GP +V + C+++ +G + Y+PI G Y I I + N HIPGSPF V Sbjct: 355 PQKIRAWGPGLEGGTVGMAASFLVEATGA----ESFAIEGPSQAKIECDDQNDGSCFVRFWPSEAGEYAVHVMCDDEEIEDSPFMACVAPK------KRGFRP---AKVKVYGPGVSPTKVLVNHKTEFTVDA----------TQAGEGLLRICIQTVDGSCVK---VDVICEEDGIYNCSYTPTAICKHTIVVSWGGVSVPGSPFTVKPGKVKIEPCSARRRRPHGSGRFCS-----DINVVSPLDIPTDAAKVKAYGPGLQGVLLGQQAEFTI------DTREAGSGRLTVIIEGPCRVTLHCVDNEDGTCVVFYLPIEHGEYLIRIYFDNS-HIPGSPFHPVV 662 HSP 3 Score: 58.9214 bits (141), Expect = 6.466e-8 Identity = 83/308 (26.95%), Postives = 120/308 (38.96%), Query Frame = 3 Query: 4968 KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP------IKKMSKTSNKDGFINVF--ASTIGVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFK 5861 +F + T G L + IEGP + + +D + G +V Y GEY+ I F+ IP SPF V P S+V + G + GK V P ++N++C V G S I + N+DG V T GVY + Y P+ V ++ S T C+V +N N + A G GL Q N +I +L + ++GPS+ ++SC E+ +G Y Y P V G Y + ITY K IPG K Sbjct: 595 EFTIDTREAGSGRLTVIIEGPCRVTLHCVDNEDGTCVVFYLPIEHGEYLIRIYFDNSHIPGSPFHPVVQ------------LPLDPSKVVVSGAGLTE-----GK-----VGEPCVVNIDC-VMAGSGDLSVQAVSDKGVIAETKVLENEDGSYTVVYVPLTAGVYTLLLKYGGKVVPNVPAAVVVDPEVYKSHVKFTGQCNVSGDPVNAE-GNHDPSKVLADGLGLFQGLTGHPNKVYI-------------NTLGIMVEGPSESKVSCKENKDGSYTMEYTPSVAGSYDVNITYGGK-SIPGQGMK 864
BLAST of Filamin A vs. Ensembl Cavefish
Match: FLNB (filamin B [Source:NCBI gene;Acc:103028460]) HSP 1 Score: 170.629 bits (431), Expect = 9.621e-42 Identity = 194/796 (24.37%), Postives = 329/796 (41.33%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD--RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP--SKTKIEC--ANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS-------TFEMPPDVECFDKLGVSSNNILVTE-------------------LEKKYFRIEC-PLNNAERLIVF-----------------------VGYFMVQVEGFPYA-IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTS---LSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243 KI++ FTRW N LK NK I DLQ DL +G L+ L+EILSQKK+ + +F + RQ ++ ++ L FL E + L +I+ I+DG++K I ++W LI HYSI + E D+ K L W+ K+ I N S W G A+G +V++C LC D W++ + NA AM+ A IPQ++ P EIID S ++++MTY+SQF + L + N K G + V GN M A + D S G+V + I+ P ++ V+AV G S + IP + G + + +I PF V V+ + + + GPGL G++A+ P F + T G+ ++ ++ P +K +E + G+ TY + G + ++I I SPY++ + ++ + ++ G+ + F +D+R++ T + P +E KL + + E + K F + P A+++ + VG +EG A I+ D N+G V + T + E +V +C D D+ + ++ ++ + SQ+K + +K G I+ + + + KG +++ + D PIE +++ K D Y + P +A K+ + VT G S+ SPF + V + S Sbjct: 16 KIQQNTFTRWCNEHLKCVNKRIADLQLDLSDGLRLIALLEILSQKKMYR-KFHQRPTFRQMKLENVSVALEFLDRENIRLVSIDSKAIVDGNLKLILGMVWTLILHYSISMPVWEGEEDDEAKKATPKQRLLGWIQHKVPDLPITNFSQDWKDGKALGALVDSCAPGLCPDWETWDTEKPVENATEAMQLADDWLGIPQVIAPEEIIDPSVDEQSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGPGIEPV----GNRVMRPAVFTVDTFS-------------AGQGQVTVYIEDPEGRRE-----EVKAVPNEGK-------------KTFSVAYIPQVMGPHKVTVLFA--GQQIPKSPFEVNVDKAQGDASKVTAKGPGLEPLGNIANKPTYFDIYTAGAGVGEVTAVIKDPQGNKNTVEALMEDKGDSVFRCTYRPVQAGPHSVNITFGGIAIPKSPYTVTVGPASSPGACRATGRGLQPRGVRVRQVADFRVDTRSAGSGELKVTVKGPKGLEEPVKLTEAMDGTYAYEYYPNTQGKYTVTITWGGQHIPKSPFEVVVGPEAGAQKIRAWGPGLEGGIVGRSADFVAESIGSDVGVLGFAIEGPSQARIECEDQNDGSCDVKYWPT-----------------EPGEYAVHVMCDD--EDIEDSPFMAYIVPDDKSSDPSQVKAYGPGLEKSGCIINKPAEFTVEAKNAGKGPLKIIAQNADGE------------PIEVKMR--NKGDNVYSCTYTPTSALKHTVAVTWGGVSVPNSPFRVNVGKGS 740 HSP 2 Score: 77.7962 bits (190), Expect = 1.298e-13 Identity = 78/306 (25.49%), Postives = 124/306 (40.52%), Query Frame = 3 Query: 4971 FVVHTSGKIPGNLAICIEGPSKAEIS--FMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 FVV+T G G ++ + P E+ ++ + G + + Y PG YV + F +IP SPF++ V D + N N T +P + F EI V P G ++ I NKDG + V K P+ + + +H + + + +Q + N N+ AYG GL N+ F I+ + +E LD+ I+GPSK +I+CI++ +G Y+P + G Y I + Y+ K HI GSPF + D Sbjct: 1635 FVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIPKSPFKVMVTDGAYIPV----------------NSMNGTGFRPFDMVIPFAFRKGEITGE---VHMPSGKTTQPEI-----IDNKDGTVMV------------------KYAPT-EAGLHEMHIKYNGSHIP-ESPLQF---YVNNANSPNVTAYGPGLVYGVANKPATFTIYTEDAAEG------GLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEK-HIAGSPFTARITED 1886 HSP 3 Score: 76.6406 bits (187), Expect = 3.413e-13 Identity = 91/343 (26.53%), Postives = 147/343 (42.86%), Query Frame = 3 Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN-ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 V++E GD + V V G+ L +G + FVV T G LA+ IEGPSK +I D G VSY T PG Y+ +I F + +P SPF + V + R + + + S+ VG ++ PEI L+++ VT P G S P ++ + N + +GV+ ++ K + +++ GS T + PL E N + A G GL++A + F I W L + ++GPS+ +IS + +G Y+ G Y + + + N+ HIP SP+ + V+ P+ D Sbjct: 1970 VQSEIGDAGR----VQVFGQGLVEGRTFEMSDFVVDTRDAGYGGLALSIEGPSKVDIQTEDMDDGTCGVSYCPTEPGTYIVSIRFAEDHVPGSPFSVKVTGEGRIR-------------ESISRRQKAASVASVGSVCDLNLKIPEIDALDMSAQVTSPSG--SVEP-AEIVEVGNHTYCVRFVPHEMGVHTVNV------------KYRGQHVPGSPFQFT---------VGPL--GEGGANKVKAGGPGLERAEIGVPAEFSI--WTREAG----AGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKF-NEEHIPESPYLVPVMA-PSDD 2261 HSP 4 Score: 72.4034 bits (176), Expect = 6.359e-12 Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 K + P +G ++ IK N I P + VN N P + +YGPGL VA+ P F + T + ++ + ++EGPSK +I C + +G+ +TY LPG Y + + NE++I SP++ I + NK Sbjct: 1755 KDGTVMVKYAPTEAGLHEMHIKYN--GSHIPESPLQFYVNNANS-PNVTAYGPGLVYGVANKPATFTIYTEDAAEGGLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDNK 1888 HSP 5 Score: 66.2402 bits (160), Expect = 4.006e-10 Identity = 35/92 (38.04%), Postives = 48/92 (52.17%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G N F ++T G L + IEGPSKAEI+ +D K G V+Y T+PG+Y + +N+ I SPF + +D RR Sbjct: 1799 VTAYGPGLVYGVANKPATFTIYTEDAAEGGLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDNKRR 1890 HSP 6 Score: 63.5438 bits (153), Expect = 2.745e-9 Identity = 35/90 (38.89%), Postives = 50/90 (55.56%), Query Frame = 3 Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNR 5189 G L + + +F + T G L+I +EGPS+AEISF D+K G VSY PG+Y ++ FN+ IP SP+ + V +DD R Sbjct: 2175 GPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLVPVMAPSDDARR 2264 HSP 7 Score: 63.1586 bits (152), Expect = 4.143e-9 Identity = 35/92 (38.04%), Postives = 47/92 (51.09%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873 + AYG GL++ T + F I + SL VTI+GPSKV++ C E G+ Y P+ G Y I I Y HI GSPF+ V+ Sbjct: 2362 VTAYGSGLERGTTGNQADFII------NTTKAGPGSLAVTIEGPSKVKMECQECSEGFKVQYTPMAPGNYLISIKYGGPNHINGSPFRAKVM 2447 HSP 8 Score: 61.2326 bits (147), Expect = 1.401e-8 Identity = 42/138 (30.43%), Postives = 68/138 (49.28%), Query Frame = 3 Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNE--YSMEIL-------NKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 KS + P S +I K E Y++EIL PF V LP + ++GPGL G + P F +DT G+ +EGP++ KIEC++ G+G+ ++Y PG Y ++I+ + ++ SP+ Sbjct: 986 GKSVPCAVEPQPGKGASLVKYIPKEEGVYTVEILYEGNPVPGSPFPVDAMLPPDPSKVKAFGPGLKGGLVGNPAEFTIDTKGAGTGGLGLTVEGPTEAKIECSDNGDGTCSVSYLPTEPGEYLVNILFEDVHVPGSPF 1123 HSP 9 Score: 60.4622 bits (145), Expect = 2.631e-8 Identity = 92/415 (22.17%), Postives = 169/415 (40.72%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIV---IVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDY-YDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQ-DLCVDTIN------DVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFG----LILYG------TSLSGRPIKKGE---CQVVQIDLDRSIQ-GGSIGFVL--EGPIETQVQCFA--------------KDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243 + PF+V V +V+ GPGL + D F + T G+ +G ++EGPS++K+ C + +GS + Y+ PG+Y ++I ++I SP+ + +V ++KV G+ K +SF +D C K GV+ + VT + ++ ++N + + VEG PY++ Y E R + + + L + S+ + +D + V + + KL K ++Q T+K ++ K G +I YG + R G+ C V + +I G +GFV+ +G + +V C +DG + I + G Y ++V G++I SPF + V++ + Sbjct: 1313 VPKSPFQVGVGEGCDPARVVAKGPGLEEGLTDKANKFSIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGVGSGVRAKIPQSFTVD-------------C-SKAGVAPLAVAVTGPKGVAEPVDV-IDNGDGTHTVA--YTPSVEG-PYSVVVKYADEEVPRSPFKLRVLPTHDASKVRASGPGLTTGLPASLPVEFTIDAKDAGEGQLSVQITDQDGKL--KTANISDNQDGTYKVSYVPDKVGRYTIVIKYGGDEIPTSPYRVRATTSGDASKCTVTGPGIGPTIGIGEEVGFVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIPKSPFKVMVTDGA 1707 HSP 10 Score: 58.5362 bits (140), Expect = 1.026e-7 Identity = 76/335 (22.69%), Postives = 129/335 (38.51%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSI------KPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P +V G L +G V + V + PG L + + SKA+ +D K G Y V+Y G Y + + +P+ P ++ V V+ + K P + E + ++ K GK++ V +P +C + + G+ K+ T ++G + V V F +G+ P+ + A G GL++ ++ N F SII + L +T++GPS+ ++SC ++ +G Y P GLY + ITY + HI GSPFK+ V Sbjct: 1133 PTKVVASGSGLKRGKVGEISVVNVDCAKAGPGQLTLEAMSDAGSKAKTEVLDNKDGTYTVTYVPLTAGMYTLLLKYGGQAVPNFPAKVVVDPAVDTSKV-KVFGPGVAGEGLFREATTDFTVDARALTKVGGKHIKAQVKNPSGAATDCVIADQGDGTY-----KVEYTPFENGVHAVEVLYDDTPVPKSPFQVGVGEGCDPA------------------------------------RVVAKGPGLEEGLTDKANKF---------SIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQ-HIQGSPFKVPV 1415 HSP 11 Score: 56.225 bits (134), Expect = 5.464e-7 Identity = 43/149 (28.86%), Postives = 66/149 (44.30%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351 P V G L +G + NKF + T G G L I +EGPS++++S D K G V Y PG Y I++ I SPF++ V D V+ S+V++ G + ++ + ++ S + L VT P G Sbjct: 1328 PARVVAKGPGLEEGLTDKANKFSIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVD------------ASKVKLSGPGVGSGVRAKIPQSFTVDCSKAGVAPLAVAVTGPKG 1464 HSP 12 Score: 53.5286 bits (127), Expect = 3.558e-6 Identity = 28/103 (27.18%), Postives = 46/103 (44.66%), Query Frame = 3 Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSS 2369 G +G +EGP E+++ C DG +++ P G Y++ +T G+ I GSPF + V + D P S + Q + + K G P V+ Sbjct: 1359 GGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGVGSGVRAKIPQSFTVDCSKAGVAPLAVAVTG 1461 HSP 13 Score: 51.9878 bits (123), Expect = 9.117e-6 Identity = 47/188 (25.00%), Postives = 86/188 (45.74%), Query Frame = 3 Query: 1197 GPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIE-CPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEG 1739 GPGL + P F I + ++EGPS+ +I + +GS ++Y A PG Y++S+ NEE+I +SPY + ++ + D+ +++ V L+ K SF + + + D + G + +V+ELE+ + I P N I V + + G P+ + + +G Sbjct: 2175 GPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLVPVMAPS--DDARRLTVTSLQESGLKVNQPTSFAVRLNGAQGAI--DAKVHSPSG-ALEECVVSELEQDKYAIRFIPRENGIHTI-DVKFNGTHIPGSPFEVRVGEPGQG 2356
BLAST of Filamin A vs. Ensembl Cavefish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145]) HSP 1 Score: 166.777 bits (421), Expect = 1.422e-40 Identity = 145/526 (27.57%), Postives = 242/526 (46.01%), Query Frame = 3 Query: 51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDE-------IGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK----VDEIKKVKVIGLENKNTKSFIIDSRNS 1532 +K +M T+ ++ + KI++ FTRW N LK NK I +LQ DL +G L+ L+E+LSQKK+ R NQ RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + + D + L W+ +KL I N S W SG A+G +V++C LC D W+ + ++NA+ AM+ A + +PQ++ P EI+D + + ++MTY+SQF L+ + N K + I+ GN M A + + IS G V + ++ P ++ AK N K+ S IP ++G + + + I PF V V + + + + GPGL G++A+ F + T G+ ++ + PS K +EC + GN S TY G + + I I SPY++ + ++ V + + ++ GL K T F + ++ + Sbjct: 24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIGLLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDTDDAKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADEWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYIPKVTGMHKVTVLFA--GLHISKSPFEVDVGMAQGDSSKVTAQGPGLEAVGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECQIEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVSVGEACNPSLCVAKGRGLQPKGLRIKETAEFKVYTKGA 512 HSP 2 Score: 99.7525 bits (247), Expect = 2.688e-20 Identity = 102/329 (31.00%), Postives = 139/329 (42.25%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L + +F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN +IP SPF + VA D RR+ + S E K N + V N + V SP C VTE ++D + + G+Y ID F G I G +K+++ Q +P +V+ AYG GL+ F + N S + +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK + Sbjct: 2104 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDENIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGEAG--------------QAGDPGMVS-------AYGAGLEGGNTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKARI 2381 HSP 3 Score: 75.8702 bits (185), Expect = 5.220e-13 Identity = 82/319 (25.71%), Postives = 131/319 (41.07%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN F V+T G L++ IEGPSKA+IS +D + G VSY +PG+Y + +N IP SP+ + D + R+ H V G++ I + ++ L +T P G +K + ++G + V +F+ +IG + NI + R S + + I I + + G GL +A F I ++ L ++I+GPSKV I+ + +G Y P G Y I I ++++ H+PGS F + V Sbjct: 1733 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPYVAKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTASLTTPSGREEPCLLKML-----RNGHVGV-------------SFVPKEIGE----HLVNIKKNGRHIP-SSPISVMINQSEIADA--SRVRVSGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 1999 HSP 4 Score: 75.0998 bits (183), Expect = 9.092e-13 Identity = 80/315 (25.40%), Postives = 142/315 (45.08%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNS-TSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900 +GK +C ++ ++ ++ + G + + Y PG+YV + F IP+SPF++ + + L + + + N G + +P+G N + V+ +L T G G P K+++ NKDG + V +A T G++ +D +K + IH + + L VD VN ++ AYG GL VN+ +F N ++ E L + I+GPSK ISC+++ +G Y+P++ G Y I + Y++K HIPGSP+ + D + ++H Sbjct: 1548 AGKGKVTCTVCTPDGAEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVMALEGASPEQLMQQTQ--VPQYAYAPNMGQPWATDRPMGMNGL-DVAGLRPFDLVIPFTIQKGEVTGEVRMPSGKVARPEIADNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDK-HIPGSPYVAKITGDDSMRMSH 1827 HSP 5 Score: 67.0106 bits (162), Expect = 2.372e-10 Identity = 41/123 (33.33%), Postives = 59/123 (47.97%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 SF P G++ I I I PF V V + ++GPGL V F+++ G D +GFS+EGPS KIEC + G+GS + Y PG Y + ++ E+I SP+ Sbjct: 542 SFEYYPTTPGNYIITITWG--GQHIPRSPFEVKVGTEAGAQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQHSPF 662 HSP 6 Score: 61.6178 bits (148), Expect = 1.221e-8 Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 K ++ P +G ++ IK + + I P + V+ N + +YGPGL + + P VF ++T + + + ++EGPSK I C + +G+ ++Y +LPG Y + + N+++I SPY Sbjct: 1689 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPY 1813 HSP 7 Score: 60.8474 bits (146), Expect = 1.753e-8 Identity = 86/341 (25.22%), Postives = 142/341 (41.64%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891 ++E D S+ V V G+ L + +F++ T G L++ IEGPSK +I+ D++ G V+Y T PG Y+ I F +P S F + V + +K I K + S+ VG + PE I ++ VT P G H + M + N I + +GV+ + S K + +++ GS T + PL ++ + A G GL++A F I W L + ++GPSK +I+ + +G YI G Y + I ++++ +IP SPF + V P+ D Sbjct: 1906 QSEIADASR----VRVSGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-NIPDSPFVVPV-ASPSDD 2196 HSP 8 Score: 58.151 bits (139), Expect = 1.161e-7 Identity = 52/197 (26.40%), Postives = 90/197 (45.69%), Query Frame = 3 Query: 924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + DL +KIP I IA ++ + +G V+K ++N +P G + +K + PF+ V + + + GPGL + A P F I + ++EGPSK +I + +GS ++Y PG Y++SI N+ENI DSP+ V+ ++ D+ +++ V L+ K Sbjct: 2024 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDENIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2211 HSP 9 Score: 55.0694 bits (131), Expect = 1.191e-6 Identity = 40/115 (34.78%), Postives = 49/115 (42.61%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVK 5213 + V TE+G +V G L G V + FVV G G L +EGPS A+I DK G V Y T PGEY + DI HSPF + +R VK Sbjct: 571 VKVGTEAG-----AQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQHSPFMAEIKPAPDRDFYPDKVK 680 HSP 10 Score: 53.1434 bits (126), Expect = 3.796e-6 Identity = 41/133 (30.83%), Postives = 58/133 (43.61%), Query Frame = 3 Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180 KPT Q+I I + G +S+ PY V V +LC KG + +F V+T G G L + I+GP E K +G +Y Y T PG Y+ I++ IP SPF + V + Sbjct: 449 KPTQEGQHI-----IYITFAGGQISKSPYTVSVGEACNPSLCVAKGRGLQPKGLRIKETAEFKVYTKGAGTGELKVTIKGPKGLEEPCKKKDLGDGVYSFEYYPTTPGNYIITITWGGQHIPRSPFEVKVGTE 576 HSP 11 Score: 53.1434 bits (126), Expect = 4.306e-6 Identity = 36/113 (31.86%), Postives = 55/113 (48.67%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK 1466 + N PFRV V + +GPGL + + P F ++T G+ MEGPS+ K+ C + +GS + Y PG Y L+I + I SP+S+ + + VD K Sbjct: 1218 VPNSPFRVPVTEGCDPARVRVHGPGLKAGLTNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCSVEYIPYEPGTYNLNITYGGQPITGSPFSVPV--QDTVDPTK 1328
BLAST of Filamin A vs. Ensembl Cavefish
Match: flncb (filamin C, gamma b (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-041008-175]) HSP 1 Score: 161.384 bits (407), Expect = 6.027e-39 Identity = 136/488 (27.87%), Postives = 222/488 (45.49%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNL----PNK-KPT---IVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 KI++ FTRW N LK NK I DLQ DL +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + E+ DE K L W+ +K+ I+N W G A+G +V+ C LC D W+ + + NA+ AM+ A +PQ++ P EI+D + + ++MTY+SQF + R+ + K I+ GN M A + ++ G ++L+ I E + V+ DKN S +P + G +K +I + PF V V+ PNK +PT I + G G G V GV I+D+ G + +E N G+ TY +L G + + + + I SP+++ I +++ + + + GL+ K + Sbjct: 16 KIQQNTFTRWCNEHLKCMNKKIGDLQRDLSDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDAKKLTPKQRLLGWIQNKVPQLPINNFHRDWRDGKALGALVDNCAPGLCPDWEMWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKTLHPKRAKAYGPGIEPRGNMVMRPAEFVVET---------------VEAGLGEVLVYIEDPEGHTEEARVIPNNDKN---------------RSYSVVYLPKVEGLHK--VKVLFAGQDINHSPFLVNVSKALGDPNKVQPTYFDIYTAGAGA-GDV----GVIIVDSQGRRDTVEIILE----------NKGDSVFRCTYGPVLEGPHVIYVTFAGQQIPRSPFTVHISEASNPNACRAIGR-GLQPKGVR 455 HSP 2 Score: 110.153 bits (274), Expect = 2.049e-23 Identity = 102/329 (31.00%), Postives = 144/329 (43.77%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRI---TVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G +F + T G L+I +EGPSKAEISF D+K G V+Y V PG+Y +I FN IP SPF + T++DD R + S EM K N + V N + V +P C++TE H I+ + + + GV++ID F G I G +K+++ Q+ +P +V+ A+G GL+ T + F + N +L VTIDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2142 HKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSIKFNDEHIPDSPFIVPIATLSDDARRLT--------VTSLQEMGLKVNHEASFAVQLNGARGVIDAKVHTPSGAVEECYITELDNDK--HAIRFIPREN-------------GVHSIDV-RFNGSHIPGSPFKIRVGEPG--------------QVGDPGMVS-------AFGPGLEGGTTGVPSDFIVNTCNAGSG------ALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV 2419 HSP 3 Score: 78.1814 bits (191), Expect = 9.990e-14 Identity = 93/408 (22.79%), Postives = 161/408 (39.46%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGG-SIGFVLE----GPIETQV--QCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSP 2273 PI +G + + I ++ I PF V V+ + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ + I+ + N F P V+C+ G+ +V + + F I+ +L ++ EG+P I D+ + STF C+ I + + I + T +V V ++ I + E+ + +YG + +K E +D + QG SIG GP E + D+ + +K+ P AG+Y + V + I SPF I V + D P Sbjct: 504 PIFTGKYTVIITWGGHA--IPRSPFEVVVSEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPF--------------------------MAHILPAANDVF--PEKVKCYGP-GLEPTGCIVNKPAE--FTIDARGAGRGQLKIYA----QDSEGYPIDIQITDNGD--------STFF-----CVYIPTKPIKHTI--------IITWGEVNVPNSPFRVTIGEGSHPEN-------------VKVYGPGVEKSGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFADQEIPISPFRIKVDPSHDANKVKAEGP 840 HSP 4 Score: 67.0106 bits (162), Expect = 2.859e-10 Identity = 84/356 (23.60%), Postives = 138/356 (38.76%), Query Frame = 3 Query: 4866 SISVKTESGDLSQIPYEVHVI-----GKALCKG-----FVNFNNKFVVHTSGKIPGNLAIC--IEGPSKAE--ISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +I++K ++ PY +H + K L G + + V+ K G + + P AE + ++ G + + Y PG+YV I F IP+SPF + V ++ + ++ K I EV M P GK H+ T NKDG + V +A T G++ +D + G+ I G + ++ I+ ++ AYG GL VN+ + F I + E L + ++GPSK +ISC ++ +G Y+P G Y I + + +K HIPGSPF + D Sbjct: 1576 TITIKYGGDEIPYSPYRIHALPSGDASKCLVTGSGLGPTIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENSDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVVRTFLSFDLQYR--KLCIMGEVRM----------PSGKTARPHI-----------------------------TDNKDGTVTVKYAPTEKGLHEMDI-KYDGNHIPGSPLQFYVDAINSG-------------------------HVTAYGPGLSHGMVNKPSIFTIVTKDAGEG------GLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDK-HIPGSPFTAKITGD 1857 HSP 5 Score: 64.6994 bits (156), Expect = 1.203e-9 Identity = 37/92 (40.22%), Postives = 47/92 (51.09%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192 V G L G VN + F + T G L++ +EGPSKAEIS D K G VSY T PG+Y + F+ IP SPF + D + R Sbjct: 1770 VTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKITGDDSMR 1861 HSP 6 Score: 64.6994 bits (156), Expect = 1.320e-9 Identity = 82/338 (24.26%), Postives = 137/338 (40.53%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTS--GKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKP-DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV--LRDPN 5885 P +V G L +G VN F V S G+ + I + ++AE+ + G Y ++Y G Y I++ +P P R+ V D ++ V+P + EV ++ + G N I + +P N + ++T+ G+ ++ T+ +DG I V + V P ++ S T CD + AYG GL++ VN+ N F + E+ L + I+GPS+ ++SC ++ +G YIP G Y + IT+ IPGSPF++ V L DP+ Sbjct: 1120 PSKVTASGPGLERGKVNEAASFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITINYGGHAVPKFPARVQVDPAVDTSGVKVFGPGVEPRGVLREVTTHFIVDTRAHNKTGGNHIKTRIVNPSGSNTDAYITDKGDGTY-----RVEYTAYEDGVHLIEVLYDEVSV--------------PKSPFRV--------SVTEGCDP--------------SRVRAYGPGLEEGLVNKPNRFTV------ETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGG-LPIPGSPFRVPVRELVDPS 1409 HSP 7 Score: 64.3142 bits (155), Expect = 1.510e-9 Identity = 84/340 (24.71%), Postives = 140/340 (41.18%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSP---EILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGP---SWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870 ++E GD S+ V V GK L +G +F+V T G L + IEGPSK +I+ D + G V+Y T PG Y+ I F +P SPF + V + ++ + + + SI VG ++ P + VT P G KT + + + Y++ F+ ++GP + K + +++ GS T + PL ++ + A G GL + F I W L + ++GPSK +IS + +G C + V+ G Y + I ++++ HIP SPF + + Sbjct: 1943 QSEIGDASK----VKVFGKGLVEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDVEDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRKK-------------ESITRRRQAPSIASVGSTCDLNLKIPGETSTREMTAQVTSPGG-----------KTDDAE----IIEGEDSTYSV---RFVPQEMGPHTVNVKYRGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGTGLDRGVAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSIKFNDE-HIPDSPFIVPI 2228 HSP 8 Score: 62.7734 bits (151), Expect = 5.600e-9 Identity = 40/132 (30.30%), Postives = 66/132 (50.00%), Query Frame = 3 Query: 1047 SNEL-SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 +NE+ + IP G + + I N + PF V +P + +YGPGL G + P F +DT G+ +EGP + KIEC + G+GS ++Y PG Y ++I+ + +I SP+ ++ Sbjct: 985 ANEVHTVKYIPPEEGPYKVDI--NYDGNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYAINILFADAHIPGSPFKAMV 1114 HSP 9 Score: 57.3806 bits (137), Expect = 2.095e-7 Identity = 40/130 (30.77%), Postives = 66/130 (50.77%), Query Frame = 3 Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNK--KPTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 ++ + IP +G I ++ N I PF++ V P + P +VS +GPGL G P FI++T N + +++GPSK K++C G +TY+ + PG Y +SI ++I SP+ Sbjct: 2289 DKHAIRFIPRENGVHSIDVRFN--GSHIPGSPFKIRVGEPGQVGDPGMVSAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEG-YKVTYTPMAPGSYLISIKYGGPQHIVGSPF 2415 HSP 10 Score: 54.299 bits (129), Expect = 1.958e-6 Identity = 36/139 (25.90%), Postives = 65/139 (46.76%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 + S P G + +KKN + N PF++ V + +G GL FI+DT + +G S+EGPSK I C ++ +G+ +TY PG Y ++I ++++ SP+++ ++ + E Sbjct: 1908 HIGISFTPKEVGEHVVSVKKN--GKHVTNSPFKIMVGQSEIGDASKVKVFGKGLVEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDVEDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRKKE 2044 HSP 11 Score: 51.9878 bits (123), Expect = 8.589e-6 Identity = 33/132 (25.00%), Postives = 65/132 (49.24%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 K ++ P G ++ IK + I P + V+ N + +YGPGL + + P +F I+ + + + ++EGPSK +I C + +G+ ++Y PG Y + + ++++I SP++ I Sbjct: 1726 KDGTVTVKYAPTEKGLHEMDIKYD--GNHIPGSPLQFYVDAINSG-HVTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKI 1854
BLAST of Filamin A vs. Ensembl Cavefish
Match: flnca (filamin-C [Source:NCBI gene;Acc:103033794]) HSP 1 Score: 151.754 bits (382), Expect = 4.765e-36 Identity = 135/507 (26.63%), Postives = 227/507 (44.77%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGL-----LQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRV----CVNLPNKKPTIVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 EM T+ E+ + KI++ FTRW N LK NK + DLQ DL +G L+ L+E+LSQKK+ + + RQ ++ ++ L FL E ++L +I+ I+DG++K I ++W LI HYSI + +++ DE + L W+ +K+ I+N + W G A+G +V+ C LC D W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + + K I+ GN M A + + + D + G V + ++ P ++ AK + N K S S +P ++G +K +I PF V V PNK + + GPGL G+V P F + T G+ + + P K + N G+ TY +L G + + + + I SP+ + I +++ + GL+ K + Sbjct: 28 EMPATEKELAEDAPWKKIQQNTFTRWCNEHLKCINKNVTDLQRDLGDGLKLIALLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDRERIKLVSIDSKAIVDGNLKLILGMIWTLILHYSISMPMWDDDDDEEKKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWETWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPRQLHPKKAKAYGPGIEPEGNMVMKPAVFTVETL-DAGL------------GEVIVYVEDPEGYREEAKVVP-----------------NNDKKRTYSVSYVPKVAGPHK--VKVLFAGQDIDKSPFSVNVAKTVGDPNK---VQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEASNASSCRATGR-GLQPKGVR 498 HSP 2 Score: 114.005 bits (284), Expect = 1.407e-24 Identity = 101/330 (30.61%), Postives = 138/330 (41.82%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRI---TVADDVNRRILHKHVKPDIC----SEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 P++V G L +G +F + T G L+I +EGPSKAEISF D+K G VSY V PG+Y +I FN IP SPF + T++DD R + + D+ + +Q G I V SP + C++T+ S I GV++ID F G I G + V++ E H +P +V+ AYG GLQ F + N +L VTIDGPSK ++ C+E GY Y P+ G Y I I Y HI GSPFK + Sbjct: 2285 PHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEASFAVQRNGARGVIDA-------KVHSPSGVVEECYITDVDADKS---------------AIRFIPRENGVHSIDV-KFNGSHIPGSPFNVRVGETGHAG---------------DPGLVS-------AYGPGLQAGCTGVPAEFVVNTCNAGSG------ALSVTIDGPSKAKMDCVECAEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKI 2563 HSP 3 Score: 92.0485 bits (227), Expect = 7.183e-18 Identity = 97/324 (29.94%), Postives = 134/324 (41.36%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFV-TEP--HGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISC--IEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G LC G VN F V T G L++ +EGPSKAEIS D K G VSY T PG+Y + F+ IP SPF + D + R +V S ++ K T + +L + +P C + T P H G SF P K++ + ++V S V N F +G +IG + +V+ A+G GL +A FF+ N L ++I+GPSKV I C +ED + Y P G Y I I ++ K HIPGSPF + V Sbjct: 1836 VTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQLNVG----SAADVSLKITETDL----SSLTASIRAPSGAEQPCLLKTLPNRHIGLSFTP-KEVGEHE-----VSVKKSGKHVNNSPFKIMVGPSEIGEASRVR-----------------------------------AFGKGLMEAHTFEVAEFFVDTRNAGYG------GLGLSIEGPSKVDIKCEDVEDGTCRV-TYCPTEPGNYIINIKFAEK-HIPGSPFTVKV 2102 HSP 4 Score: 69.3218 bits (168), Expect = 5.930e-11 Identity = 46/161 (28.57%), Postives = 79/161 (49.07%), Query Frame = 3 Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRNS 1532 P + G + + I I PF V V + + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + +KV+ G + T F ID+R + Sbjct: 547 PTVPGKYTVTITWG--GQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQA 705 HSP 5 Score: 66.6254 bits (161), Expect = 3.292e-10 Identity = 96/392 (24.49%), Postives = 158/392 (40.31%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDK----------IGPSWKV-------------KIENIHGSLRSTTLSCDVDIQ---------IINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SVK ++ P+++ V IG +A KG + + +F V T G L + IEGPSK +I D + G V+Y T PG Y+ I F + IP SPF + V + + I+ K P I S ++ ++ GN + + L F SS +++ GG + +++ +K +D F ++F S +G ++ + L K P KV + + + S T+S Q + PL ++ + A G GLQ+ F I W L + ++GPSK +IS + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 1989 VSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKESIMRKRQAPSIASVGTICDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVHVEESTKVGGRDPFRDIFGSILGRESLGCFGSLTSKEDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHK-VRAGGTGLQRGIAGVPTEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNE-HIPDSPFIVPI 2372 HSP 6 Score: 62.3882 bits (150), Expect = 6.665e-9 Identity = 50/195 (25.64%), Postives = 87/195 (44.62%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEM 1544 N+ V+ V +G C + +K + IP G + + + + + PF V +P + +YGPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y G Y ++I+ E++I SP+ + + + V GLE +F +D SR E+ Sbjct: 1006 NVGVKMVSPSGRPIPCKLEPDRAK-GVTNVKYIPPEEGQYKVDVSYD--GNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPALDASRV-TVSGPGLERAKAGEVATFTVDCSRAGEAEL 1196 HSP 7 Score: 60.077 bits (144), Expect = 3.488e-8 Identity = 73/290 (25.17%), Postives = 116/290 (40.00%), Query Frame = 3 Query: 5028 PSKAE--ISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 P AE + ++ G + + Y PG+YV I F IP+SPF + + K + E Q + +P+ + F V L V P G ++ I+ NKDG + V +A T G++ +D + G+ I G + ++ + + AYG GL TVN+ F + N +E L + ++GPSK +ISC ++ +G Y+P G Y I + + K HIPGSPF + D Sbjct: 1692 PDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHV------------QATKEPVVPRDEKQPQ-----FRPINLLIPFTVQQGA---LTGEVRMPSGKTARPLIR-----DNKDGTVTVKYAPTERGLHEMDI-KYDGNHIPGSPLQFFVDAAESGM-------------------------VTAYGPGLCHGTVNKPATFTVVTKNAAEG------GLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGK-HIPGSPFTAKITGD 1923 HSP 8 Score: 58.151 bits (139), Expect = 1.360e-7 Identity = 37/139 (26.62%), Postives = 69/139 (49.64%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 + S P G ++ +KK+ + N PF++ V + + ++G GL + F +DT N +G S+EGPSK I+C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 1974 HIGLSFTPKEVGEHEVSVKKS--GKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKE 2110 HSP 9 Score: 55.0694 bits (131), Expect = 9.634e-7 Identity = 72/306 (23.53%), Postives = 124/306 (40.52%), Query Frame = 3 Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPD-ICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 +G+ + I + + AE+ + G + V+Y G Y +I + +P P RI V D ++ V+P + +V ++ + +G N I + +P N + +T+ G+ ++ T+ +DG I VF + V P ++ + G CD + AYG GL+ VN+ N F + E+ L +TI+G S+ ++SC ++ +G Y+P + G Y I ITY + IPGSPF + V RD Sbjct: 1191 AGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTY-----RVEYTAFEDGLHLIEVFYDEVAV--------------PKSPFRVSVVEG--------CDP--------------SRVRAYGPGLEGGIVNKPNCFTV------ETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQ-PIPGSPFHVLV-RD 1447 HSP 10 Score: 54.299 bits (129), Expect = 1.779e-6 Identity = 47/192 (24.48%), Postives = 88/192 (45.83%), Query Frame = 3 Query: 960 KDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSL--IPILSGSFDIFIKKNEYSMEILNKPFRVCVNL-----PNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSF 1511 K+ + + + G V N +S + ++S+ +P GS + +K + + PF+ V P+K + + G GL +A P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + D+ +++ V L+ K+ + + Sbjct: 2215 KEDVQGMTAQVTSPGGKVV----NAELVESGDSTYSVRFVPTEMGSHTVSVKYS--GQHVPGSPFQFTVGPLGEGGPHK---VRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DDARRLTVTSLQEKDLRVY 2395 HSP 11 Score: 53.9138 bits (128), Expect = 2.407e-6 Identity = 85/326 (26.07%), Postives = 124/326 (38.04%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATV--NRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING--YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864 P V G L G VN N F V T G G L + IEG S+A++S D K G V Y IPG Y I++ IP SPF + V D V+ S+V+ G + ++ V + S + +L+ + P G + P+ + +N DG +N S G Y + D +KV H + + A G GL +A V + F I + E ++ + +D K + + I+D Y Y+P V G Y I I Y IP SP+ I Sbjct: 1358 PSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVD------------ASKVKCSGPGLGSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGAT--EPVAVL---NNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDA------------------------SKVRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQ-----ILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGD-QIPFSPYSI 1636 HSP 12 Score: 53.1434 bits (126), Expect = 4.190e-6 Identity = 35/121 (28.93%), Postives = 60/121 (49.59%), Query Frame = 3 Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 + + PFRV V + +YGPGL G + + P F ++T G+ ++EG S+ K+ C + +GS + Y +PG Y ++I + I SP+ +++ V + KVK G Sbjct: 1341 VAVPKSPFRVSVVEGCDPSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLV---RDVVDASKVKCSG 1458 HSP 13 Score: 53.1434 bits (126), Expect = 4.297e-6 Identity = 41/135 (30.37%), Postives = 63/135 (46.67%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVI 1436 +++ + IP +G I +K N I PF V V P +VS YGPGL P F+++T N + +++GPSK K++C G I Y+ + PG Y +SI ++I SP+ I Sbjct: 2432 ADKSAIRFIPRENGVHSIDVKFN--GSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEG-YKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKI 2563
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004210.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004210.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.9821 bits (245), Expect = 9.904e-21 Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3 Query: 357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I+DG++K I L+W LI HYSI + E+ D+ K L W+ KL I N S W G A+G +V++C LC D W+ ++NA+ AM+ A + Q++ P EI+D + + ++MTY+SQF Sbjct: 5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140 HSP 2 Score: 70.8626 bits (172), Expect = 3.297e-12 Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927 + A+G GL++ T F + ++ SL V IDGPSKV++ C E GY FCY+P GLY + I Y HI GSP++ V P H E FL Sbjct: 2023 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2125 HSP 3 Score: 66.2402 bits (160), Expect = 9.444e-11 Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3 Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 I PF V V+ + ++GPGL +A F+++ G+D +GFS+EGPS+ +I C + G+GS + Y PG Y + ++ +EE++ SP+ I+ +++ Sbjct: 440 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 548 HSP 4 Score: 64.6994 bits (156), Expect = 2.747e-10 Identity = 39/96 (40.62%), Postives = 48/96 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRIL 5198 V G L G V + F + T G L++ +EGPSKAEIS D K G VSY T PG+Y A+ F IP SP+ RI +D R L Sbjct: 1762 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASL 1857 HSP 5 Score: 63.5438 bits (153), Expect = 6.422e-10 Identity = 68/290 (23.45%), Postives = 111/290 (38.28%), Query Frame = 3 Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLI------------FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888 G + + + T PG YV A+ F IP+SPF + V R P Q S + G +L FH+ P L E H S ++ N+DG ++V + I G++ +D YN G + ++ + G ++ AYG GL V + F I ++ E L + ++GPSK +ISC ++ +G Y+P G Y I + ++ + HIPGSP+ ++ +S Sbjct: 1597 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGP-------------------------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIIAGEDS 1852 HSP 6 Score: 60.8474 bits (146), Expect = 4.082e-9 Identity = 112/518 (21.62%), Postives = 198/518 (38.22%), Query Frame = 3 Query: 804 SSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNIL---VTELEKKYFRI-ECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKF----------GLILYGTSLSGRP--IKKGE---------CQVVQIDLDRSIQG--------------GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDG-KSIDGSPFSITVS 2234 S D G + M IST+++ +H+ P ++ G + + +P+ K A +++ R+G +S S PI G ++ IK N + + P + V+ P++ +YGPGL + F +DT + + + ++EGPSK +I C + +G+ ++Y PG Y +++ ++I SPY ++I E+ S + SR ST ++ S IL +LE R+ CP + V V + + G P+ + E R+V S L E ++ N A+ L+ + + V+T + + E S++ KWI +F + G S+ G P ++ GE L+R G GS+ ++GP + +V C +G Y + P G Y + + G I GSP+ V+ Sbjct: 1660 SQTCGDAGLSLAMSEDISTESLRPFHLVV----PFSLRKGHITGEVHMPSGRK--ASPRIID-----------NRDGT------MSVSFAPIEKGLHEMDIKYNGHHIPT-GSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPY--------------MARIIAGEDSLRASLL--SRGSTHDV-------------SLRILELHCEDLEDGRCRVWYCPPEPGD-YEVSVRFEDEHIPGSPFLLTVDGVCEESRRV----AVSGLLESGWKV-NHPASFAVHLNGAKGRI----EAKVHTPSGSV----ENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEG-YHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVT 2108 HSP 7 Score: 57.3806 bits (137), Expect = 4.190e-8 Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514 + PF + LP + +G GL G P F +DT + +G ++EGP + ++EC + G+G+ ++Y + G Y ++I+ + ++ SP++ V+ S E V+V G + +F+ Sbjct: 931 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1056 HSP 8 Score: 55.8398 bits (133), Expect = 1.130e-7 Identity = 69/343 (20.12%), Postives = 139/343 (40.52%), Query Frame = 3 Query: 1329 NGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK----KVKVIGLENKNTKSFIIDSRNST-FEMPPDVECFDKLGVSSNNILVTELEKKY---FRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDS-NEGQRKVDQFSTFSSLQEKC---LEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKH-------ETFEESQLKTFKWIDKKFGLILYGTSLSGRP---------IKKGECQV-VQIDLDRSIQG-GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVS---ETSDTGVF 2258 N ++ + Y+ G + + + +E+ + DSP+ I +V S+ +++ + G+E F + +R + E+ DV+ D ++ IL +E+ + + ++ + + V Y V G P+ + + G+ +V+ T L+ C + ++ + +L + L T V ++ ++H ET T+ L L P ++ GE + + +D + G G +G +EGP E +++C DG + + P+ AG+Y + + + GSPF+ V ETS VF Sbjct: 708 NDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAEL--DVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGT--KLEMGCEQEVRVVTRGAGGRGQLEAR-LLSPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVF 1045 HSP 9 Score: 55.0694 bits (131), Expect = 2.348e-7 Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186 P V V G L G + N F + T G L + +EGP +A ++F + G + V Y PGEY+ I++ I SPF + V D+VN Sbjct: 1232 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1325 HSP 10 Score: 51.2174 bits (121), Expect = 3.206e-6 Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183 P +V V G+ L G V +F V T+ G L + +EGP +A + D G VSY GEY I F +P SPF V V Sbjct: 946 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1037 HSP 11 Score: 49.6766 bits (117), Expect = 9.888e-6 Identity = 33/97 (34.02%), Postives = 45/97 (46.39%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 + V E+G P +V G L G + FVV G G L IEGPS+A I+ D+ G V Y T PG+Y + ++ D+ SPF Sbjct: 448 VLVSAEAG-----PQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 539
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004223.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235187:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004223.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.9821 bits (245), Expect = 1.091e-20 Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3 Query: 357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I+DG++K I L+W LI HYSI + E+ D+ K L W+ KL I N S W G A+G +V++C LC D W+ ++NA+ AM+ A + Q++ P EI+D + + ++MTY+SQF Sbjct: 5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140 HSP 2 Score: 70.8626 bits (172), Expect = 3.343e-12 Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927 + A+G GL++ T F + ++ SL V IDGPSKV++ C E GY FCY+P GLY + I Y HI GSP++ V P H E FL Sbjct: 2264 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2366 HSP 3 Score: 66.2402 bits (160), Expect = 8.289e-11 Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3 Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 I PF V V+ + ++GPGL +A F+++ G+D +GFS+EGPS+ +I C + G+GS + Y PG Y + ++ +EE++ SP+ I+ +++ Sbjct: 437 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 545 HSP 4 Score: 64.6994 bits (156), Expect = 2.390e-10 Identity = 37/94 (39.36%), Postives = 47/94 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRIL 5198 V G L G V + F + T G L++ +EGPSKAEIS D K G VSY T PG+Y A+ F IP SP+ + +D R L Sbjct: 1699 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASL 1792 HSP 5 Score: 63.5438 bits (153), Expect = 5.974e-10 Identity = 70/274 (25.55%), Postives = 112/274 (40.88%), Query Frame = 3 Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 G + + + T PG YV A+ F IP+SPF + + DI +E S++P FH+ P L E H S ++ N+DG ++V + I G++ +D +K H RS L VD ++ P ++ AYG GL V + F I ++ E L + ++GPSK +ISC ++ +G Y+P G Y I + ++ + HIPGSP+ + D Sbjct: 1574 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAMSE------------DISTE----------SLRP------FHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMD--------------IKYNGHHIPSRSP-LQFYVD-EMDGP--------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIRED 1786 HSP 6 Score: 58.5362 bits (140), Expect = 2.125e-8 Identity = 35/128 (27.34%), Postives = 64/128 (50.00%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + +S S PI G ++ IK N + + P + V+ P++ +YGPGL + F +DT + + + ++EGPSK +I C + +G+ ++Y PG Y +++ ++I SPY Sbjct: 1654 RDGTMSVSFAPIEKGLHEMDIKYNGHHIP-SRSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPY 1779 HSP 7 Score: 57.3806 bits (137), Expect = 3.992e-8 Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514 + PF + LP + +G GL G P F +DT + +G ++EGP + ++EC + G+G+ ++Y + G Y ++I+ + ++ SP++ V+ S E V+V G + +F+ Sbjct: 917 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1042 HSP 8 Score: 55.0694 bits (131), Expect = 2.371e-7 Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186 P V V G L G + N F + T G L + +EGP +A ++F + G + V Y PGEY+ I++ I SPF + V D+VN Sbjct: 1222 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1315 HSP 9 Score: 52.7582 bits (125), Expect = 1.113e-6 Identity = 41/174 (23.56%), Postives = 77/174 (44.25%), Query Frame = 3 Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT---IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVIVKSNKVDEIKKVKVIGLEN-KNTKSFIIDSRNSTFEM 1544 S+ ++++ +P +G + + + S + PFRV V P + ++GPGL P F++DT+G+ + +++GPSK +++C+ G Y PG+Y +SI +I SPY + ++ G N T SF++++ M Sbjct: 2215 SEIDKVAARFVPRENGVHPVSVTCDGAS--VPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSE-GPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRA---------RVTGPRLSGGHNLHETSSFLVEAGEPRRAM 2376 HSP 10 Score: 51.2174 bits (121), Expect = 3.235e-6 Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183 P +V V G+ L G V +F V T+ G L + +EGP +A + D G VSY GEY I F +P SPF V V Sbjct: 932 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1023 HSP 11 Score: 51.2174 bits (121), Expect = 3.345e-6 Identity = 35/127 (27.56%), Postives = 57/127 (44.88%), Query Frame = 3 Query: 1101 FIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-----SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 + E + + PFRV V + + G GL + FI+DT + GF SMEGPS+ ++ C ++ +G + Y PG Y L+I EE I SP+++++ + E Sbjct: 1851 LVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDT----RYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQKE 1973 HSP 12 Score: 49.6766 bits (117), Expect = 9.972e-6 Identity = 33/97 (34.02%), Postives = 45/97 (46.39%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 + V E+G P +V G L G + FVV G G L IEGPS+A I+ D+ G V Y T PG+Y + ++ D+ SPF Sbjct: 445 VLVSAEAG-----PQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 536
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004195.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004195.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.5969 bits (244), Expect = 1.264e-20 Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3 Query: 357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 I+DG++K I L+W LI HYSI + E+ D+ K L W+ KL I N S W G A+G +V++C LC D W+ ++NA+ AM+ A + Q++ P EI+D + + ++MTY+SQF Sbjct: 5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140 HSP 2 Score: 70.8626 bits (172), Expect = 3.370e-12 Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3 Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927 + A+G GL++ T F + ++ SL V IDGPSKV++ C E GY FCY+P GLY + I Y HI GSP++ V P H E FL Sbjct: 2402 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2504 HSP 3 Score: 66.6254 bits (161), Expect = 7.362e-11 Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3 Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451 I PF V V+ + ++GPGL +A F+++ G+D +GFS+EGPS+ +I C + G+GS + Y PG Y + ++ +EE++ SP+ I+ +++ Sbjct: 440 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 548 HSP 4 Score: 64.6994 bits (156), Expect = 2.801e-10 Identity = 39/96 (40.62%), Postives = 48/96 (50.00%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRIL 5198 V G L G V + F + T G L++ +EGPSKAEIS D K G VSY T PG+Y A+ F IP SP+ RI +D R L Sbjct: 1756 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASL 1851 HSP 5 Score: 63.1586 bits (152), Expect = 8.006e-10 Identity = 68/298 (22.82%), Postives = 115/298 (38.59%), Query Frame = 3 Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPD-----------ICSE---------VEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888 G + + + T PG YV A+ F IP+SPF + V R P +C + M ++ S++P FH+ P L E H S ++ N+DG ++V + I G++ +D YN G + ++ + G ++ AYG GL V + F I ++ E L + ++GPSK +ISC ++ +G Y+P G Y I + ++ + HIPGSP+ ++ +S Sbjct: 1589 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRP------FHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGP-------------------------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIIAGEDS 1846 HSP 6 Score: 60.077 bits (144), Expect = 6.597e-9 Identity = 36/133 (27.07%), Postives = 66/133 (49.62%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439 + +S S PI G ++ IK N + + P + V+ P++ +YGPGL + F +DT + + + ++EGPSK +I C + +G+ ++Y PG Y +++ ++I SPY I+ Sbjct: 1711 RDGTMSVSFAPIEKGLHEMDIKYNGHHIPT-GSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARII 1841 HSP 7 Score: 57.7658 bits (138), Expect = 3.631e-8 Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514 + PF + LP + +G GL G P F +DT + +G ++EGP + ++EC + G+G+ ++Y + G Y ++I+ + ++ SP++ V+ S E V+V G + +F+ Sbjct: 923 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1048 HSP 8 Score: 55.0694 bits (131), Expect = 2.384e-7 Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186 P V V G L G + N F + T G L + +EGP +A ++F + G + V Y PGEY+ I++ I SPF + V D+VN Sbjct: 1224 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1317 HSP 9 Score: 53.9138 bits (128), Expect = 5.036e-7 Identity = 49/214 (22.90%), Postives = 89/214 (41.59%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT---IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVIVKSNKVDEIKKVKVIGLEN-KNTKSFIIDSRNSTFEM 1544 GR++ + P+ +N V +DK+ K + L+ +P +G + + + S + PFRV V P + ++GPGL P F++DT+G+ + +++GPSK +++C+ G Y PG+Y +SI +I SPY + ++ G N T SF++++ M Sbjct: 2329 GRIEAKVHTPS---GSVENCFVSEIDKD-------------KWSLLAARFVPRENGVHPVSVTCDGAS--VPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSE-GPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRA---------RVTGPRLSGGHNLHETSSFLVEAGEPRRAM 2514 HSP 10 Score: 51.2174 bits (121), Expect = 3.066e-6 Identity = 35/127 (27.56%), Postives = 57/127 (44.88%), Query Frame = 3 Query: 1101 FIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-----SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 + E + + PFRV V + + G GL + FI+DT + GF SMEGPS+ ++ C ++ +G + Y PG Y L+I EE I SP+++++ + E Sbjct: 1910 LVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDT----RYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQKE 2032 HSP 11 Score: 51.2174 bits (121), Expect = 3.252e-6 Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183 P +V V G+ L G V +F V T+ G L + +EGP +A + D G VSY GEY I F +P SPF V V Sbjct: 938 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1029
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.2117 bits (243), Expect = 1.853e-20 Identity = 82/276 (29.71%), Postives = 133/276 (48.19%), Query Frame = 3 Query: 63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSV---LIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS----FLNWLNSKLDGY---FIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAIST 860 E R K+ + ++KK FT+W+N L + I DL DL +G +L++L+E+LS +KL K + RI L +V L FL+ + + L+N+ DI+DG+ + I L+W +I + I+ E ++ +S L W K GY I N +++W G+A IV+ DL + K SNA +N Q A A Q + +LL P +I +K+I+TYV + + + GK + V++ T M+ T Sbjct: 44 ERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPK----PTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVETEDNKERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDL-IEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPEDISVDQPDEKSIITYVVTYYHYFSKM--KALAVEGKRIGKVLESAIETDQMIDKYET 312
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006506.1 (pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006506.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 90.5077 bits (223), Expect = 2.489e-18 Identity = 71/232 (30.60%), Postives = 115/232 (49.57%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL---GENNFDEIGKSFLNW---LNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATD-KAIMTYVSQFSGLLQERNNN 776 +++KK FT+WIN L+ I DL DL +G+ L+ L+E LS + IR + R + + VL +L+ + ++L NI DI+DG+ K L+W +I HY +F G ++ + + L W + + G N SS+W G + IV+ R D+ + A N + A+ A +P+LL P E +D A D K+I+TYVS L +++ Sbjct: 7 RVQKKTFTKWINSHLQQVRMNIGDLYEDLRDGQALISLLESLSGDCI--IREKGRLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHYQNASFAHIEGNHSSMQSRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVH-AHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDP-EDVDVDAPDEKSIITYVSALHNALHKQDGQ 234
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO46947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL3]) HSP 1 Score: 129.028 bits (323), Expect = 1.520e-29 Identity = 75/221 (33.94%), Postives = 122/221 (55.20%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGK-----SFLNWLNSKL-DGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 KI++ FTRW N LK +F+ L+ DLC+G L+ L+++LSQK+L + + +I ++ L F+ E + L NI+ DI+ G++K I L+W LI Y I +++ DE K + L W+ SK+ + +DN ++ WN G AI +V+ L + + +AL NAQ AM+ A IPQ+L P ++++ + ++MTYVS F Sbjct: 365 KIQQNTFTRWCNEHLKCVKQFVYSLETDLCDGLKLIALLQVLSQKRLPRFNKKPVFKSQKIENVSISLKFIEDENIRLVNIDASDIVKGNLKLILGLIWTLILKYQISMPYLDDDDDENHKMTPKQALLAWVKSKMPESVPMDNFTTHWNDGRAIACLVDAVAPGLLPECEDLDPKDALQNAQQAMKLAQDWLDIPQVLDPADMVNPKVDELSMMTYVSYF 585 HSP 2 Score: 107.071 bits (266), Expect = 7.974e-23 Identity = 105/362 (29.01%), Postives = 160/362 (44.20%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV-------------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV-SSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY-NFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906 I+VK +S P++V+V G L +G V F V T PG LAI +EGP+KAEI+ D G +SY T PGEY I F DIP SPF++ V +V R + +K S++E S+ +K VG+ F V ++ + ++ V P G S I + K G Y I F GD + VK + H + + V +P + + AYG GL + F + ++ +L +++DGP+KV+++C E+ +G Y Y P+V G Y I I ++ + HIP SP+ +T+ P+ L H E Sbjct: 2961 INVKYRGRHISGSPFKVYVEAPVWGGAAKCTAAGPGLERGVVGHPGDFTVWTRDAGPGGLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADEDIPGSPFKVFVTTEVEDRF--RDLK---LSDLE------SSGLK-VGQPASFSVQTNAPVGKVSATVIAPSGTESKAVISDLGK---------------GNYAIRFVPKEFGDHL---VNVKFDETH--IPGSPFKIRVGGGGAHP-------EKVKAYGPGLSSGHAGKSAEFTV------NALEAGSGALALSVDGPAKVKMNCTENQDGTYQVTYYPVVAGEYTISIKFAGQ-HIPDSPYNVTIF-PPSGHLQHSE 3275 HSP 3 Score: 85.8853 bits (211), Expect = 1.650e-16 Identity = 98/350 (28.00%), Postives = 147/350 (42.00%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHVI-----------GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN--LNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV ++ PYEV V G L +G N F V T G +L IEGP++AEI +D G V+Y +PG+Y ++ VDI +SPF + ++ + S+V + G G F V + E + ++ V + G S IK NKDG V + G++ + + DK P K+ NI + T C AYG GL++ V+++N F I E+ E L +TI+GPS+ +I CI++ +G Y P G Y + I Y++K HIPGSPFK + Sbjct: 981 VSVTWSGEQAAKSPYEVKVATAVDASRIKAYGPGLERGIANKPCHFTVETKGAGVDSLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGD------------ASKVYAKGPGLEPEGVCAGCPAEFTVYTNEAGDGDVDIKVMDSQGKKSPSEIK-----DNKDGTYTVTYYPDKPGMHTVAVH--FNDKPIPKSPFKV-NI---CSTNTSKCR-------------------AYGPGLEKGFVDQRNDFKI------ETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADK-HIPGSPFKARI 1281 HSP 4 Score: 78.5666 bits (192), Expect = 3.332e-14 Identity = 90/355 (25.35%), Postives = 145/355 (40.85%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRIL---HKHVKPDICSEVE--MQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG----------GSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIEN-IHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI---TVLRDPNSDLNHQEFEN 5915 +V V G L KG +F V+T G L + IEGPSKAEI+ +D + G V Y T PG+Y I F +P SPF+ + I+ V+ + V ++ + + P + +F + + +L V P G G++ + I+ M K S + INV + G I G +KV +E + G T A G GL++ V F ++ + L + ++GP+K +I+C ++ +G Y+P G Y I I ++++ IPGSPFK+ T + D DL + E+ Sbjct: 2782 KVKVTGDGLRKGVTGEPARFTVNTRDAGYGGLGLSIEGPSKAEINCVDNEDGTCSVDYLPTEPGKYTINIKFADEHVPGSPFKANIRRPGEEEIVAMSEDGVESEPTQRVSQVFEDLVSFGAAAPQPHDFVFDLKGYNVEDLETTVISPDGEVLPAEIVESGTNSYTIRFMPKESGEH-VINV-------------KYRGRHISGSPFKVYVEAPVWGGAAKCT-----------------------AAGPGLERGVVGHPGDFTVWTRDAGPG------GLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADE-DIPGSPFKVFVTTEVEDRFRDLKLSDLES 3092 HSP 5 Score: 70.8626 bits (172), Expect = 6.031e-12 Identity = 46/184 (25.00%), Postives = 85/184 (46.20%), Query Frame = 3 Query: 918 DGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNK-PFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEI 1463 DG +D+ ++ P E+ V+ + N Y C F ++ +S E K P+ V V I +YGPGL +A+ P F ++T G+ +GF++EGP++ +I+C ++G+G +TY L+PG Y + + + +I +SP+ + I + ++ Sbjct: 941 DGELDVFVEGPLGEEK------VDIKNNNDGTYSCI-----------------YFPSKFGKYVVSVTWSGEQAAKSPYEVKVATAVDASRIKAYGPGLERGIANKPCHFTVETKGAGVDSLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGDASKV 1101 HSP 6 Score: 63.929 bits (154), Expect = 8.994e-10 Identity = 48/158 (30.38%), Postives = 73/158 (46.20%), Query Frame = 3 Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 S +N + +P SG I +K I PF+V V P + GPGL V PG F + T + + ++EGP+K +I C + G+GS I+Y PG Y + I +E+I SP+ V V + D + +K+ LE+ K Sbjct: 2942 SGTNSYTIRFMPKESGEHVINVKYR--GRHISGSPFKVYVEAPVWGGAAKCTAAGPGLERGVVGHPGDFTVWTRDAGPGGLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADEDIPGSPFK-VFVTTEVEDRFRDLKLSDLESSGLK 3096 HSP 7 Score: 61.6178 bits (148), Expect = 4.181e-9 Identity = 45/162 (27.78%), Postives = 78/162 (48.15%), Query Frame = 3 Query: 1029 NGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 N + N LS S +P +G + +KK+ + PF V V+ P + G GL V P F ++T + +G S+EGPSK +I C + +G+ + Y PG Y ++I +E++ SP+ I + + +EI + G+E++ T+ Sbjct: 2731 NLTLNSDNTLSVSFVPQETGEHFVSVKKS--GKHVTGSPFSVMVSGPGPADASKVKVTGDGLRKGVTGEPARFTVNTRDAGYGGLGLSIEGPSKAEINCVDNEDGTCSVDYLPTEPGKYTINIKFADEHVPGSPFKANIRRPGE-EEIVAMSEDGVESEPTQ 2889 HSP 8 Score: 60.4622 bits (145), Expect = 1.035e-8 Identity = 39/135 (28.89%), Postives = 65/135 (48.15%), Query Frame = 3 Query: 4860 LDSISVKTESGDLSQIPYEVHVI----------GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA---DDVNRRILHKHVKPDIC 5225 + +++V + + P++V++ G L KGFV+ N F + T G G L + IEGPS+A+I +D G V Y PG+Y+ I + IP SPF+ ++ D ++ ++P IC Sbjct: 1168 MHTVAVHFNDKPIPKSPFKVNICSTNTSKCRAYGPGLEKGFVDQRNDFKIETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADKHIPGSPFKARISHPFDPSKVKVEGPGIEPGIC 1302 HSP 9 Score: 60.077 bits (144), Expect = 1.277e-8 Identity = 47/171 (27.49%), Postives = 83/171 (48.54%), Query Frame = 3 Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG--------LENKNTKSFIIDS 1523 ++ S P G D+ +K + I PF+V V LP P+ +YGPGL + + P F ++T G+ + ++EGPS+ K+ C + G+G+ ++Y + G Y + I +E+I SP++ K+ + + KVK G L +K + F +D+ Sbjct: 1535 NQDGSFGVSYTPFEEGIHDLAVKFGD--DHIPGSPFKVDV-LPVTDPSKCKAYGPGLQHAQLNKPADFTVETKGAGAGGLSLAIEGPSEAKLTCQDNGDGTCSVSYIPVEEGDYDIHIKFADEHIPGSPFT---AKAGRPVDPSKVKCHGPGVDRVNPLFSKTPQRFTVDT 1699 HSP 10 Score: 58.151 bits (139), Expect = 4.279e-8 Identity = 41/119 (34.45%), Postives = 64/119 (53.78%), Query Frame = 3 Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484 I PF+V + N +YGPGL D F ++T G+ + +G ++EGPS+ KI+C + G+GS + Y PG Y ++I+ +++I SP+ I S+ D KVKV G Sbjct: 1180 IPKSPFKVNICSTNTSKC-RAYGPGLEKGFVDQRNDFKIETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADKHIPGSPFKARI--SHPFDP-SKVKVEG 1294 HSP 11 Score: 57.3806 bits (137), Expect = 7.141e-8 Identity = 34/84 (40.48%), Postives = 41/84 (48.81%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159 P V GK L +G +F V T PG L++ +EGPSKAEI D G V+Y PGEY + F IP SPF Sbjct: 2061 PGAVKAFGKGLERGLAKEPCEFTVVTRDAGPGGLSLAVEGPSKAEIKCQDNGDGSCNVTYVPDEPGEYNINVKFADKHIPGSPF 2144 HSP 12 Score: 55.4546 bits (132), Expect = 3.404e-7 Identity = 73/274 (26.64%), Postives = 107/274 (39.05%), Query Frame = 3 Query: 5073 YIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLR--DPN 5885 Y Y G Y +SF P SPFR+ VA N + + Q G T+I S L VT P G + I T N+DG + GV F + D VK + H + + DV + + +P AYG GLQ A +N+ F + E+ L + I+GPS+ +++C ++ +G YIP+ G Y I I ++++ HIPGSPF R DP+ Sbjct: 1445 YKCDYIAPAEGPYNVKVSFGDKPAPGSPFRVNVAKAGN------------AGKCKAQGDGLETAIINQLAEFDVDCSQAGEGQLMASVTNPSGAHTDTLI-----TDNQDG-------SFGVSYTPFEEGIHD-----LAVKFGDDH--IPGSPFKVDV-LPVTDP-------SKCKAYGPGLQHAQLNKPADFTV------ETKGAGAGGLSLAIEGPSEAKLTCQDNGDGTCSVSYIPVEEGDYDIHIKFADE-HIPGSPFTAKAGRPVDPS 1672 HSP 13 Score: 54.6842 bits (130), Expect = 4.884e-7 Identity = 36/128 (28.12%), Postives = 61/128 (47.66%), Query Frame = 3 Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436 + +P G + +K +E I PF++ V P V +YGPGL A F ++ + S++GP+K K+ C +G+ +TY ++ G Y +SI ++I DSPY++ I Sbjct: 3139 AIRFVPKEFGDHLVNVKFDE--THIPGSPFKIRVGGGGAHPEKVKAYGPGLSSGHAGKSAEFTVNALEAGSGALALSVDGPAKVKMNCTENQDGTYQVTYYPVVAGEYTISIKFAGQHIPDSPYNVTI 3264 HSP 14 Score: 52.7582 bits (125), Expect = 2.087e-6 Identity = 22/70 (31.43%), Postives = 36/70 (51.43%), Query Frame = 3 Query: 2064 SIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSP 2273 S+GF +EGP + +++C DG+ + + P+ GKY + VT I SPF + +S D + P Sbjct: 1037 SLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGDASKVYAKGP 1106
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO45254 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE6]) HSP 1 Score: 114.775 bits (286), Expect = 2.295e-25 Identity = 71/220 (32.27%), Postives = 119/220 (54.09%), Query Frame = 3 Query: 102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL---GENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDK-AIMTYVSQFS 749 +I+K FT W N +++ I DL +G +V L+E +++KK + + + + Q ++ L L +G++L NI+ DI++G++K I L+W LI HY I + G+ K+ L L I N+++ WNSGIA+ ++N CD L TD + N N++ N + AM+ A F IPQ+L P E+ + D+ ++MTY+S F+ Sbjct: 40 EIQKNTFTNWCNEQIRESGIVITDLAIAFNDGVTIVYLVESVAEKKCKNCKMNPKFVQDKLENTTQALKLLENDGIQLVNIDNQDIVNGNLKLIMGLIWRLILHYQISSSASASGKQLLLLWLKNALPELK-------IGNVTTDWNSGIALAALINFCDPRLMTDWREMNPDNSIANVKKAMKCAEDNFRIPQILSP-ELFASPYVDELSMMTYLSFFT 251 HSP 2 Score: 51.6026 bits (122), Expect = 4.429e-6 Identity = 62/254 (24.41%), Postives = 107/254 (42.13%), Query Frame = 3 Query: 4968 KFVVHTSGKIPGNLAICIEGPSKA-EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDF-YN--------FLGDKIGPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVN-----RKNHFFIFLWNYS 5678 KF V T+ G LAI +GP+ + G Y VSY PG+YV +FN D+P SP R +VA D ++ + H D +VE+ + G + H ++ L ++ G + P++ + + + D + + +G++ I YN FL K+ + KV++ +N+H S R + +VD+ + P E + G ++ + NH F+ N S Sbjct: 567 KFEVDTTSAGLGELAIKCKGPTGGIPVDVRATARGKYQVSYLPNTPGDYVTHCTFNGEDVPESPLR-SVAGDPDKIVAHG----DGLYQVEVGSPGEFF--------ITLHGAARGGLEVSG-----DGPNGHFPVELVESSRDNDTYTVRFMPQGVGIHKIHIRYNGRPVRGSPFL-VKVSDASKVRLSKNVHTSGRGHVIRHEVDVPLEVPREAGEGELSATCVGPDMESVATSVTKERDGNHHIRFMPNRS 801
BLAST of Filamin A vs. Ensembl Nematostella
Match: ALPHA-ACTININ (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4X0]) HSP 1 Score: 94.3597 bits (233), Expect = 3.285e-19 Identity = 71/258 (27.52%), Postives = 133/258 (51.55%), Query Frame = 3 Query: 99 HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-----KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGY---FIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATD-KAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVID-DGGNTSMM 842 + +KK FT W N L+ K I +++ DL +G +L++L+EI+S ++L K+RF RI +N L F+ +G++L ++ +I+DG++K ++W +I ++I+ E++F + G L W K Y + N ++++ G+A +++ DL D + L N A + A Q IP++L P ++++T D +A+MTYVS + ++ + D K + V++ + N MM Sbjct: 26 ERQQKKTFTAWCNSHLRKTGKQIGEIEEDLRDGVLLLQLLEIISGERLPHPERGKLRF------HRIANVNKALDFVAGKGVKLVSVGAEEIVDGNLKMTLGMIWTIILRFAIQDIAIEDSFAKDG--LLLWCQRKTAPYKNVSVKNFTTSFKDGLAFCALIHRHRPDLI-DYDSLRKEDPLYNLNKAFDVAEQYLDIPRMLDPEDMVETERPDERAVMTYVSSYYHAFT--SSQQADTAAKRIGKVLNINRDNERMM 272
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0]) HSP 1 Score: 93.2041 bits (230), Expect = 9.506e-19 Identity = 74/237 (31.22%), Postives = 120/237 (50.63%), Query Frame = 3 Query: 63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSV---LIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIK--TFLGENNFDEIGK-SFLNWLNSKLDGYF---IDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746 E R K + +++KK FT+WIN L+ + +L DL +G L+ L+E+LS +KL K ++ R RI L +V L+FL+ + + L+N+ DI+DG+ K L+W +I + I+ T GE K + L W SK GY I N +++W G+A I++ DL + K ++A N + A E A I LL ++ +K+I+TYV+ + Sbjct: 11 ERSRIKVLADERERVQKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPK---PSKGRM-RIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITIEGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDL-IEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAY 242
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO30309 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T157]) HSP 1 Score: 85.1149 bits (209), Expect = 3.427e-18 Identity = 64/221 (28.96%), Postives = 115/221 (52.04%), Query Frame = 3 Query: 111 KKVFTRWINHKLKYHNK---FIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGY--FIDNLSSAWNSGIAIGLIVNTCDRDL--CTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTY 734 +K FT+W+N KL H I+D+ DL +G +L+ L+E+L++KKL+K + R +I + L+ L ++L I DI+DG + I LLW +I + ++ + + E KSF L W +LDGY I++ SS+W +G+A I+++ + + T+V + ++ L + A ++A F +P++L ++ K I+ Y Sbjct: 13 RKAFTKWVNSKLADHPTEPCTIKDVVTDLQDGRMLLNLLEVLTRKKLKKEK--GNLRVHKINNVERALVLLDECKIKLVGINGFDIVDGKHRVILGLLWSIILRFQVEEVMQQEVNAESAKSFTIEKRLLEWCRERLDGYDVEINDFSSSWQNGLAFSAILHSYNPEAFDYTEVKQMGTTERL---EHAFQSAEDGFDVPRILDASDVNVPRPDKKLIILY 228
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476]) HSP 1 Score: 160.999 bits (406), Expect = 8.982e-39 Identity = 135/488 (27.66%), Postives = 227/488 (46.52%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNK-PFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454 EM T+ ++ + KI++ FTRW N LK NK I DLQ D +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + ++ DE K L W+ +K+ I+N + W G A+G +V+ C LC D + W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + R + K I+ GN + A + + + G V + ++ P K+ AK V DK G + + P + G + K ++ + ++K P+ V V+ P+ V + GPGL G+VA+ P F + T G+ + I + P K + N G+ TY +L G + + I+ + I SP+ + I ++ V Sbjct: 27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRGT---------------YTVTYTPKVEGVHKV---KVLFAGQDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481 HSP 2 Score: 104.76 bits (260), Expect = 9.443e-22 Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G ++F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + +A D RR+ K +K + + +Q G + V +P C+V+E S I GV++ID VK H GS ++++ +P ++ + + A+G GLQ T + F + N +L V IDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2279 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2556 HSP 3 Score: 86.6557 bits (213), Expect = 2.927e-16 Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN + F V T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF +IT D + R L+ D+ ++ E + SI+ N P +L + H G SF P + + + KDG I V N F +G +IG + +VK A+G GL +A FF+ N L ++I+GPSKV I+C + +G Y P G Y + I ++ K HIPGSPF + V Sbjct: 1851 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2118 HSP 4 Score: 74.7146 bits (182), Expect = 1.087e-12 Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586 N+ V+ +G C + +K N S IP G + + + N +L PF V +P + ++GPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y PG Y ++I+ E++I SP+ I + +D IK V GLE +F +D SR E+ +E + GV + Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246 HSP 5 Score: 67.781 bits (164), Expect = 1.341e-10 Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526 G +++ +K PT ++ V+ D VY+C P+ +G + + I I PF V V + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + N E K GL+ NK T+ F ID+R Sbjct: 553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741 HSP 6 Score: 64.6994 bits (156), Expect = 1.243e-9 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3 Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 ++ ++ + G + + Y PG+YV I F +IP SPF++ ++ V P ++ P+ + + F V +P+ + V P G ++ I T NKDG I + + G++ +D +K + H + + L VD +N +V AYG GL VN+ F + N E L + ++GPSK +I+C ++ +G Y+P G Y I + + NK HIPGSPF + D Sbjct: 1713 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1938 HSP 7 Score: 60.8474 bits (146), Expect = 1.860e-8 Identity = 95/373 (25.47%), Postives = 148/373 (39.68%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV+ + ++ P+++ V IG KA KG + + +F V T G LA+ IEGPSK +I+ D + G V+Y T PG Y I F + IP SPF + V + RI + S + ++K G N VS+ E L F H + ++SKT + + V ST +G F + GD +G + + S + Q I P VN Y+ + A G GL++ + F I W L + ++GPSK +I+ + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 2005 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGE--GRIKESITRKRQASSLASVGSTCGLNLKIPG-NWFQMVSAQERLT-RTFTRSSHTYTRTER-TEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2365 HSP 8 Score: 58.5362 bits (140), Expect = 1.077e-7 Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 L S P G ++ ++K+ + + N PF++ V + + ++G GL + F +DT N + S+EGPSK I C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 1990 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2126 HSP 9 Score: 55.8398 bits (133), Expect = 6.554e-7 Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3 Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + + GPGL VA P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + DE +++ V L+ K+ K Sbjct: 2281 VRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2386 HSP 10 Score: 55.0694 bits (131), Expect = 1.141e-6 Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 S++ + IP +G I +K N I PF V V P P +V ++GPGL G P F++ T N + +++GPSK K++C G ITY+ + PG Y ++I ++I SP+ Sbjct: 2425 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2552
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476]) HSP 1 Score: 160.614 bits (405), Expect = 1.006e-38 Identity = 136/487 (27.93%), Postives = 225/487 (46.20%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454 EM T+ ++ + KI++ FTRW N LK NK I DLQ D +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + ++ DE K L W+ +K+ I+N + W G A+G +V+ C LC D + W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + R + K I+ GN + A + + + G V + ++ P K+ AK V DK G Y T ++ E + + +G +I P+ V V+ P+ V + GPGL G+VA+ P F + T G+ + I + P K + N G+ TY +L G + + I+ + I SP+ + I ++ V Sbjct: 27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481 HSP 2 Score: 104.375 bits (259), Expect = 1.197e-21 Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G ++F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + +A D RR+ K +K + + +Q G + V +P C+V+E S I GV++ID VK H GS ++++ +P ++ + + A+G GLQ T + F + N +L V IDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2279 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2556 HSP 3 Score: 86.2705 bits (212), Expect = 3.587e-16 Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN + F V T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF +IT D + R L+ D+ ++ E + SI+ N P +L + H G SF P + + + KDG I V N F +G +IG + +VK A+G GL +A FF+ N L ++I+GPSKV I+C + +G Y P G Y + I ++ K HIPGSPF + V Sbjct: 1851 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2118 HSP 4 Score: 74.7146 bits (182), Expect = 1.245e-12 Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586 N+ V+ +G C + +K N S IP G + + + N +L PF V +P + ++GPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y PG Y ++I+ E++I SP+ I + +D IK V GLE +F +D SR E+ +E + GV + Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246 HSP 5 Score: 67.781 bits (164), Expect = 1.498e-10 Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526 G +++ +K PT ++ V+ D VY+C P+ +G + + I I PF V V + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + N E K GL+ NK T+ F ID+R Sbjct: 553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741 HSP 6 Score: 64.6994 bits (156), Expect = 1.448e-9 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3 Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 ++ ++ + G + + Y PG+YV I F +IP SPF++ ++ V P ++ P+ + + F V +P+ + V P G ++ I T NKDG I + + G++ +D +K + H + + L VD +N +V AYG GL VN+ F + N E L + ++GPSK +I+C ++ +G Y+P G Y I + + NK HIPGSPF + D Sbjct: 1713 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1938 HSP 7 Score: 60.4622 bits (145), Expect = 2.375e-8 Identity = 95/373 (25.47%), Postives = 148/373 (39.68%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV+ + ++ P+++ V IG KA KG + + +F V T G LA+ IEGPSK +I+ D + G V+Y T PG Y I F + IP SPF + V + RI + S + ++K G N VS+ E L F H + ++SKT + + V ST +G F + GD +G + + S + Q I P VN Y+ + A G GL++ + F I W L + ++GPSK +I+ + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 2005 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGE--GRIKESITRKRQASSLASVGSTCGLNLKIPG-NWFQMVSAQERLT-RTFTRSSHTYTRTER-TEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2365 HSP 8 Score: 58.151 bits (139), Expect = 1.153e-7 Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 L S P G ++ ++K+ + + N PF++ V + + ++G GL + F +DT N + S+EGPSK I C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 1990 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2126 HSP 9 Score: 55.8398 bits (133), Expect = 7.255e-7 Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3 Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 + + GPGL VA P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + DE +++ V L+ K+ K Sbjct: 2281 VRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2386 HSP 10 Score: 55.0694 bits (131), Expect = 1.232e-6 Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 S++ + IP +G I +K N I PF V V P P +V ++GPGL G P F++ T N + +++GPSK K++C G ITY+ + PG Y ++I ++I SP+ Sbjct: 2425 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2552
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476]) HSP 1 Score: 160.614 bits (405), Expect = 1.065e-38 Identity = 136/487 (27.93%), Postives = 225/487 (46.20%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454 EM T+ ++ + KI++ FTRW N LK NK I DLQ D +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + ++ DE K L W+ +K+ I+N + W G A+G +V+ C LC D + W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + R + K I+ GN + A + + + G V + ++ P K+ AK V DK G Y T ++ E + + +G +I P+ V V+ P+ V + GPGL G+VA+ P F + T G+ + I + P K + N G+ TY +L G + + I+ + I SP+ + I ++ V Sbjct: 27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481 HSP 2 Score: 104.375 bits (259), Expect = 1.318e-21 Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G ++F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + +A D RR+ K +K + + +Q G + V +P C+V+E S I GV++ID VK H GS ++++ +P ++ + + A+G GLQ T + F + N +L V IDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2329 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2606 HSP 3 Score: 86.2705 bits (212), Expect = 3.752e-16 Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN + F V T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF +IT D + R L+ D+ ++ E + SI+ N P +L + H G SF P + + + KDG I V N F +G +IG + +VK A+G GL +A FF+ N L ++I+GPSKV I+C + +G Y P G Y + I ++ K HIPGSPF + V Sbjct: 1873 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2140 HSP 4 Score: 74.3294 bits (181), Expect = 1.440e-12 Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586 N+ V+ +G C + +K N S IP G + + + N +L PF V +P + ++GPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y PG Y ++I+ E++I SP+ I + +D IK V GLE +F +D SR E+ +E + GV + Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246 HSP 5 Score: 67.781 bits (164), Expect = 1.578e-10 Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526 G +++ +K PT ++ V+ D VY+C P+ +G + + I I PF V V + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + N E K GL+ NK T+ F ID+R Sbjct: 553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741 HSP 6 Score: 64.3142 bits (155), Expect = 1.525e-9 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3 Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 ++ ++ + G + + Y PG+YV I F +IP SPF++ ++ V P ++ P+ + + F V +P+ + V P G ++ I T NKDG I + + G++ +D +K + H + + L VD +N +V AYG GL VN+ F + N E L + ++GPSK +I+C ++ +G Y+P G Y I + + NK HIPGSPF + D Sbjct: 1735 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1960 HSP 7 Score: 58.5362 bits (140), Expect = 9.760e-8 Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV+ + ++ P+++ V IG KA KG + + +F V T G LA+ IEGPSK +I+ D + G V+Y T PG Y I F + IP SPF + V + + I K + S + ++ GN + + L F SS +++ GG + ++ T G F +VF +G ++ + L + PS K V + + G S+T S Q I P VN Y+ + A G GL++ + F I W L + ++GPSK +I+ + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 2027 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2415 HSP 8 Score: 58.151 bits (139), Expect = 1.235e-7 Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 L S P G ++ ++K+ + + N PF++ V + + ++G GL + F +DT N + S+EGPSK I C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 2012 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2148 HSP 9 Score: 56.6102 bits (135), Expect = 3.619e-7 Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L G N N+F V T G G L + IEG S+A+IS D K G V Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1396 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1488 HSP 10 Score: 56.6102 bits (135), Expect = 4.210e-7 Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 S+ S IP G + +K + PF+ V + + + GPGL VA P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + DE +++ V L+ K+ K Sbjct: 2285 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2436 HSP 11 Score: 54.6842 bits (130), Expect = 1.287e-6 Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 S++ + IP +G I +K N I PF V V P P +V ++GPGL G P F++ T N + +++GPSK K++C G ITY+ + PG Y ++I ++I SP+ Sbjct: 2475 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2602 HSP 12 Score: 53.1434 bits (126), Expect = 3.708e-6 Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532 K S +P G +D+ I N I PFRV V P + GPGL G A P F +D T + + GP+ T + N G+G+ + Y+ G Y +S+ +++ + SP+ ++ + ++ + GL+ K + F ID+R++ Sbjct: 1447 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1615
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476]) HSP 1 Score: 160.229 bits (404), Expect = 1.203e-38 Identity = 135/487 (27.72%), Postives = 223/487 (45.79%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454 EM T+ ++ + KI++ FTRW N LK NK I DLQ D +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + ++ DE K L W+ +K+ I+N + W G A+G +V+ C LC D + W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + R + K I+ GN + A + + + G V + ++ P K+ AK V DK G + + P + G +K +I P+ V V+ P+ V + GPGL G+VA+ P F + T G+ + I + P K + N G+ TY +L G + + I+ + I SP+ + I ++ V Sbjct: 27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRGT---------------YTVTYTPKVEGVHK--VKVLFAGQDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481 HSP 2 Score: 104.375 bits (259), Expect = 1.209e-21 Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G ++F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + +A D RR+ K +K + + +Q G + V +P C+V+E S I GV++ID VK H GS ++++ +P ++ + + A+G GLQ T + F + N +L V IDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2299 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2576 HSP 3 Score: 86.2705 bits (212), Expect = 3.622e-16 Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN + F V T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF +IT D + R L+ D+ ++ E + SI+ N P +L + H G SF P + + + KDG I V N F +G +IG + +VK A+G GL +A FF+ N L ++I+GPSKV I+C + +G Y P G Y + I ++ K HIPGSPF + V Sbjct: 1843 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2110 HSP 4 Score: 74.3294 bits (181), Expect = 1.450e-12 Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586 N+ V+ +G C + +K N S IP G + + + N +L PF V +P + ++GPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y PG Y ++I+ E++I SP+ I + +D IK V GLE +F +D SR E+ +E + GV + Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246 HSP 5 Score: 67.781 bits (164), Expect = 1.512e-10 Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526 G +++ +K PT ++ V+ D VY+C P+ +G + + I I PF V V + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + N E K GL+ NK T+ F ID+R Sbjct: 553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741 HSP 6 Score: 64.3142 bits (155), Expect = 1.833e-9 Identity = 82/313 (26.20%), Postives = 124/313 (39.62%), Query Frame = 3 Query: 5028 PSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNRRILHKHVKPDICSEVEMQNKGNSTSI----KPVGKNLIF-HVSSPEILNLN------------CFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY-------NFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 P A I D + G Y VSY G Y I + +IP+SP+RI D ++ +L V S ++ T I K GK + V +P+ + L+ + T P G I+ + K F V A+ V D NFL + K N+ S+R T+ + Q + + + + AYG GL VN+ F + N E L + ++GPSK +I+C ++ +G Y+P G Y I + + NK HIPGSPF + D Sbjct: 1631 PKNATIQ--DNRDGTYTVSYVPDSTGPYTITIKYGGDEIPYSPYRIQSLPTGDASKCLLTVSVGGHGMSSLQKLQTSEDTVITVDAKAAGKGKVTCKVLTPQGMELDMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPF-QVMATNEPVVPRDTVDPLFRPVNFLVPFTPQCRQGKPTNLQREASMRWTSNMMETTFQFYVDAVNSGV---VTAYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1930 HSP 7 Score: 58.5362 bits (140), Expect = 8.964e-8 Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV+ + ++ P+++ V IG KA KG + + +F V T G LA+ IEGPSK +I+ D + G V+Y T PG Y I F + IP SPF + V + + I K + S + ++ GN + + L F SS +++ GG + ++ T G F +VF +G ++ + L + PS K V + + G S+T S Q I P VN Y+ + A G GL++ + F I W L + ++GPSK +I+ + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 1997 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2385 HSP 8 Score: 58.151 bits (139), Expect = 1.213e-7 Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 L S P G ++ ++K+ + + N PF++ V + + ++G GL + F +DT N + S+EGPSK I C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 1982 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2118 HSP 9 Score: 56.6102 bits (135), Expect = 3.525e-7 Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L G N N+F V T G G L + IEG S+A+IS D K G V Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1396 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1488 HSP 10 Score: 56.6102 bits (135), Expect = 4.032e-7 Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 S+ S IP G + +K + PF+ V + + + GPGL VA P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + DE +++ V L+ K+ K Sbjct: 2255 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2406 HSP 11 Score: 55.0694 bits (131), Expect = 1.243e-6 Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 S++ + IP +G I +K N I PF V V P P +V ++GPGL G P F++ T N + +++GPSK K++C G ITY+ + PG Y ++I ++I SP+ Sbjct: 2445 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2572 HSP 12 Score: 53.1434 bits (126), Expect = 3.863e-6 Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532 K S +P G +D+ I N I PFRV V P + GPGL G A P F +D T + + GP+ T + N G+G+ + Y+ G Y +S+ +++ + SP+ ++ + ++ + GL+ K + F ID+R++ Sbjct: 1447 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1615
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476]) HSP 1 Score: 160.229 bits (404), Expect = 1.459e-38 Identity = 135/484 (27.89%), Postives = 224/484 (46.28%), Query Frame = 3 Query: 63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445 EM T+ ++ + KI++ FTRW N LK NK I DLQ D +G L+ L+E+LSQKK+ + + + RQ ++ ++ L FL E ++L +I+ I+DG++K I L+W LI HYSI + ++ DE K L W+ +K+ I+N + W G A+G +V+ C LC D + W+ + + NA+ AM+ A +PQ++ P EI+D + ++MTY+SQF + R + K I+ GN + A + + + G V + ++ P K+ AK V DK G Y T ++ E + + +G +I P+ V V+ P+ V + GPGL G+VA+ P F + T G+ + I + P K + N G+ TY +L G + + I+ + I SP+ + I ++ Sbjct: 27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEA 478 HSP 2 Score: 104.375 bits (259), Expect = 1.303e-21 Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L +G ++F + T G L+I +EGPSKAEI+F D+K G VSY V PG+Y +I FN IP SPF + +A D RR+ K +K + + +Q G + V +P C+V+E S I GV++ID VK H GS ++++ +P ++ + + A+G GLQ T + F + N +L V IDGPSKV++ C E GY Y P+ G Y I I Y HI GSPFK V Sbjct: 2290 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2567 HSP 3 Score: 86.2705 bits (212), Expect = 3.650e-16 Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 V G L G VN + F V T G L++ +EGPSKAEI+ D K G VSY T PG+Y + F+ IP SPF +IT D + R L+ D+ ++ E + SI+ N P +L + H G SF P + + + KDG I V N F +G +IG + +VK A+G GL +A FF+ N L ++I+GPSKV I+C + +G Y P G Y + I ++ K HIPGSPF + V Sbjct: 1834 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2101 HSP 4 Score: 74.7146 bits (182), Expect = 1.155e-12 Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3 Query: 975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586 N+ V+ +G C + +K N S IP G + + + N +L PF V +P + ++GPGL G + P F +DT G+ ++EGP + KIEC + G+G+ ++Y PG Y ++I+ E++I SP+ I + +D IK V GLE +F +D SR E+ +E + GV + Sbjct: 1005 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1207 HSP 5 Score: 68.1662 bits (165), Expect = 1.184e-10 Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3 Query: 921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526 G +++ +K PT ++ V+ D VY+C P+ +G + + I I PF V V + ++GPGL + F+++ G++ +GFS+EGPS+ KIEC + G+GS + Y PG Y + ++ ++E+I DSP+ I+ + N E K GL+ NK T+ F ID+R Sbjct: 514 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 702 HSP 6 Score: 64.6994 bits (156), Expect = 1.460e-9 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3 Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879 ++ ++ + G + + Y PG+YV I F +IP SPF++ ++ V P ++ P+ + + F V +P+ + V P G ++ I T NKDG I + + G++ +D +K + H + + L VD +N +V AYG GL VN+ F + N E L + ++GPSK +I+C ++ +G Y+P G Y I + + NK HIPGSPF + D Sbjct: 1696 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1921 HSP 7 Score: 58.5362 bits (140), Expect = 9.037e-8 Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3 Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 +SV+ + ++ P+++ V IG KA KG + + +F V T G LA+ IEGPSK +I+ D + G V+Y T PG Y I F + IP SPF + V + + I K + S + ++ GN + + L F SS +++ GG + ++ T G F +VF +G ++ + L + PS K V + + G S+T S Q I P VN Y+ + A G GL++ + F I W L + ++GPSK +I+ + +G YI G Y + I ++N+ HIP SPF + + Sbjct: 1988 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2376 HSP 8 Score: 58.5362 bits (140), Expect = 9.424e-8 Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3 Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460 L S P G ++ ++K+ + + N PF++ V + + ++G GL + F +DT N + S+EGPSK I C ++ +G+ +TY PG Y ++I E++I SP+++ + ++ E Sbjct: 1973 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2109 HSP 9 Score: 56.6102 bits (135), Expect = 3.268e-7 Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505 S+ S IP G + +K + PF+ V + + + GPGL VA P F I + ++EGPSK +I + +GS ++Y PG Y++SI N E+I DSP+ + I + DE +++ V L+ K+ K Sbjct: 2246 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2397 HSP 10 Score: 56.6102 bits (135), Expect = 3.554e-7 Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186 P V G L G N N+F V T G G L + IEG S+A+IS D K G V Y PG+Y I++ IP SPFR+ V D V+ Sbjct: 1357 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1449 HSP 11 Score: 55.0694 bits (131), Expect = 1.059e-6 Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3 Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424 S++ + IP +G I +K N I PF V V P P +V ++GPGL G P F++ T N + +++GPSK K++C G ITY+ + PG Y ++I ++I SP+ Sbjct: 2436 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2563 HSP 12 Score: 53.5286 bits (127), Expect = 3.184e-6 Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532 K S +P G +D+ I N I PFRV V P + GPGL G A P F +D T + + GP+ T + N G+G+ + Y+ G Y +S+ +++ + SP+ ++ + ++ + GL+ K + F ID+R++ Sbjct: 1408 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1576 HSP 13 Score: 51.9878 bits (123), Expect = 9.649e-6 Identity = 35/146 (23.97%), Postives = 67/146 (45.89%), Query Frame = 3 Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV 1478 K ++ P G ++ IK + I P + V+ N + +YGPGL YG V ++ N + + ++EGPSK +I C + +G+ ++Y PG Y + + + ++I SP++ I + + ++ V Sbjct: 1790 KDGTITIKYQPTERGLHEMDIKYD--GNHIPGSPLQFYVDAVNSG-VVTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNV 1932
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1) HSP 1 Score: 3724.48 bits (9657), Expect = 0.000e+0 Identity = 1905/1951 (97.64%), Postives = 1905/1951 (97.64%), Query Frame = 3 Query: 66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY N NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ Sbjct: 1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1907
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1) HSP 1 Score: 3715.62 bits (9634), Expect = 0.000e+0 Identity = 1905/1957 (97.34%), Postives = 1905/1957 (97.34%), Query Frame = 3 Query: 66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTD------MKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTD MKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY N NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ Sbjct: 1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDCFFNFYMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1913
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1) HSP 1 Score: 3704.84 bits (9606), Expect = 0.000e+0 Identity = 1900/1951 (97.39%), Postives = 1900/1951 (97.39%), Query Frame = 3 Query: 66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIG PSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY N NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ Sbjct: 1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIG-----PSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1902
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1) HSP 1 Score: 3648.98 bits (9461), Expect = 0.000e+0 Identity = 1880/1951 (96.36%), Postives = 1883/1951 (96.51%), Query Frame = 3 Query: 66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDK + + F+ N L I SFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY N NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ Sbjct: 1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDK----IQLLQMETFT--NVLG---TEIFQRSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1898
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000064795.1 (SMESG000064795.1) HSP 1 Score: 189.889 bits (481), Expect = 1.003e-47 Identity = 201/782 (25.70%), Postives = 338/782 (43.22%), Query Frame = 3 Query: 105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS-------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLV---VEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLY--GSVADCPGVFILDT-NGSDQQIGFSMEGPS--KTKI--ECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEI----KKVKVIGLENKNTKSFIIDSRNST--------------------FEMPPD-VECF--------DKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAI--------ELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246 I+K FTRW+N LK N+ I DLQ D +G L+ LIE+LS+ K R ++ + VL FL EG++L NI+ DI+D +K I L+W LI HYSI + E ++ +S ++W+ ++ + NL++ WN G AIG +V++C LC D +W +AL + + AM+ A Q +PQL+KP E+ID + +KA+MTY+SQF + + + N NK + G + S G T+ D GR +L I I D A L+ +E + N YKCT P G++ I ++ E +I PF+V ++ + P+ V GPG+ G + FI+ T + +I + PS K KI + S + Y+A G++ ++I ++ I +SP+ +++ + + + ++ G+ + F ID++N+ E+ P+ EC +L ++ +NI VT + F+I + F V G AI D+N G+ FS + K NQD I E +V LC D+ + ++ +E + S++K + +K G+ L + E + I+ I+ + F G E V + + +Y +QP+T G +++FV+ D +S+ SPF + V++ S+ Sbjct: 17 IQKNTFTRWVNVHLKKANQSINDLQNDFSDGIRLMTLIEVLSEHKFTHANKRTNFRTQKLENVTMVLRFLEEKEGLKLINIDSSDIVDCRLKLILGLVWALILHYSISMPIWEGEDSKVHESKQTPKQRMMSWITGRMPEKHVKNLTTDWNDGTAIGALVDSCAPGLCPDWAEWKPVDALIHTKEAMDTAEQWLNVPQLIKPEEMIDPNVDEKAMMTYLSQFPNAKVNPGAPITSKLNPNKVRVYGPGIESKDLIAGQTAEFTV-------------------DAFSAGRGNLDITI----TDNAGKLIDVKIEEIPDKKNCYKCT--------------YTPPCKGTYTITVRYAE--KDIPRSPFKVIIDKTSGDPSKVKVKGPGIEQNGVIVSTSTYFIISTEDAGTGEISCVVLSPSGDKDKINPKITQESPTSYRVEYTAEETGVHSINIFLSSAQIKNSPFGVMVSPRSNAKLVTVSGRGIQSNGIRVGDKAEFFIDTQNAGNGKLNVKLLSPEKSEESVKIAEINPNYFECLYIPSKPGMYELQINYDNIPVT---RSPFKINVLPTKTSHIAAFGPGLTTGVVG-KAAIFVTDTN-GELGSLGFSIEGPSEAKIECCDNQDGSATICYWPTAPGEYAVHILCDG--EDIPNSPYMANIMPSNEKTDVSKIKVYGPGVQKEGVALNSPN---------EFTIDCIEYKSDIKPEASCFTCSG-NEIPVVISSAGNKKYRCVYQPLTDGNHKVFVSCDNQSVPKSPFKVKVAQPSN 742 HSP 2 Score: 118.627 bits (296), Expect = 4.963e-26 Identity = 104/328 (31.71%), Postives = 143/328 (43.60%), Query Frame = 3 Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN------LNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 ++V G L G + N+F ++T G L+I IEGPSKAEI F D+K G V Y VT PGEY+C+I FN I +SPFRI VN + + D S + + + +GK F V+ P+ L + P I+ + K FI G + I+ + + +K G ++V I H +P +V+ A GDGL V +KNHF + N L+VTIDGPSKVQ+ E+ GY F YIP G Y I + Y HI GSPF + Sbjct: 3024 HKVVASGNGLKLGHTSGPNEFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVKYFVTEPGEYICSIKFNDDHIINSPFRIM----VNEKQM------DFISVASVGDNALAKEWT-IGKPAAFTVNYPQTTTIRSDGKLRATIVGPSRTEEPAIIQNIEKNQYAIRFI---PKESGEHLINVTDEITNKHIPGSPFRVVIGQQHA----------------DPGMVH-------AKGDGLMSGFVGKKNHFIVNTLNSGTG------PLNVTIDGPSKVQLYSQENEEGYEFIYIPSAPGEYQITVKYGGNYHIAGSPFTANI 3308 HSP 3 Score: 91.2781 bits (225), Expect = 9.685e-18 Identity = 93/338 (27.51%), Postives = 138/338 (40.83%), Query Frame = 3 Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNKDG--FINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDL 5894 +V G L G +F + T G L++ IEGPSKAEI D + G V+Y IPG+Y I F +IP SPF + + RR IC STS P+ N + +I L V P G +KKM S T + G FINV+ S + F +G ++IG + KV++ +G+GL+ N N F + ++ L ++I+GPSK +I C ++ +G Y P G Y I I Y+N+ H+ GSPF + + +P++ L Sbjct: 2651 KVAAYGPGLSHGRTGLPAEFTIVTKDAGAGGLSLAIEGPSKAEIVCKDNENGSCDVTYYPLIPGDYSIIIKFADHNIPGSPFIANIIGEPQRR-------SQICI--------GSTSDVPLKINNL------DISTLTASVRAPSGKEESCILKKMPNDNLGISFTPREVGNHFINVYQSGAHILGSPFKIVVGQNEIGDASKVRV-----------------------------------FGEGLKCGISNEMNSFTV------DTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANE-HVSGSPFAVKITGEPSAKL 2925 HSP 4 Score: 67.781 bits (164), Expect = 1.088e-10 Identity = 89/338 (26.33%), Postives = 132/338 (39.05%), Query Frame = 3 Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870 + E GD S+ V V G+ L G N N F V T G L++ IEGPSKAEI D G VSY + PG Y+ I + + SPF + + + + +++ K IC + + I VG L V ++ VT +G + I + DG I +G++ + V+ N+H GS T + P IV+ + A G+GL+ + N F I+ L + I+GPSK +I + +G Y G Y I + N HI SPF+I V Sbjct: 2824 QNEIGDASK----VRVFGEGLKCGISNEMNSFTVDTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANEHVSGSPFAVKITGEPSAKLMEKI----ICRQ-------EAADITQVGSQCELTLKVPGTHHSDMRATVTNLYGTTEVCEIIDLD-----DGHYSIKFIPKEMGLHTV--------------VVQHRNMHIPGSPFQFT---------VGP-IVDGGAHKVVASGNGLKLGHTSGPNEFSIYTREAGAG------GLSIAIEGPSKAEIDFEDRKDGSCGVKYFVTEPGEYICSIKF-NDDHIINSPFRIMV 3110 HSP 5 Score: 65.0846 bits (157), Expect = 7.758e-10 Identity = 35/79 (44.30%), Postives = 42/79 (53.16%), Query Frame = 3 Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDI 5144 P +V V G+ L GF N N F + G GNL + IEGPS A+I+ D G V Y TIPG Y I FN VD+ Sbjct: 937 PSKVLVFGEGLEGGFTNQPNFFTIDLDGAGQGNLGLAIEGPSDAKINCTDNLDGTCTVEYSSTIPGTYDIYIKFNDVDV 1015 HSP 6 Score: 64.3142 bits (155), Expect = 1.242e-9 Identity = 51/198 (25.76%), Postives = 98/198 (49.49%), Query Frame = 3 Query: 999 KNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNS-------TFEMPPDVECF 1565 K+G++ K +G++S S+S P +G++ + + + + I N PF + V +P P+ ++ +G GL G + P F +D +G+ Q +G ++EGPS KI C + +G+ + YS+ +PG Y + I N+ ++ P + +S + + + E S ++ NS TF PD++ + Sbjct: 886 KSGSMVKSNGDGSYS----CSYS--PYDAGTYILDVTYED--LPIKNSPFNIEV-VPGCDPSKVLVFGEGLEGGFTNQPNFFTIDLDGAGQGNLGLAIEGPSDAKINCTDNLDGTCTVEYSSTIPGTYDIYIKFNDVDVNGFPKHVFHRESTYEELLSLNAPMDDERTEADSILLSFNNSSGHDENLTFPKVPDIDSY 1074 HSP 7 Score: 57.3806 bits (137), Expect = 1.759e-7 Identity = 31/85 (36.47%), Postives = 44/85 (51.76%), Query Frame = 3 Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171 + G L G V FV T+G++ G+L IEGPS+A+I D + G + Y T PGEY I + DIP+SP+ + Sbjct: 553 IAAFGPGLTTGVVGKAAIFVTDTNGEL-GSLGFSIEGPSEAKIECCDNQDGSATICYWPTAPGEYAVHILCDGEDIPNSPYMANI 636 HSP 8 Score: 56.6102 bits (135), Expect = 2.911e-7 Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 3 Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424 + +YGPGL P F I+ + + ++EGPSK +I C + NGS +TY L+PG Y + I + NI SP+ Sbjct: 2652 VAAYGPGLSHGRTGLPAEFTIVTKDAGAGGLSLAIEGPSKAEIVCKDNENGSCDVTYYPLIPGDYSIIIKFADHNIPGSPF 2732 HSP 9 Score: 55.8398 bits (133), Expect = 5.196e-7 Identity = 38/142 (26.76%), Postives = 68/142 (47.89%), Query Frame = 3 Query: 1056 LSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCV--NLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKV 1472 L S P G+ FI + IL PF++ V N + +G GL +++ F +DT + + S+EGPSK +IEC + +G+ ++Y+ PG Y ++I E++ SP+++ I ++K+ Sbjct: 2790 LGISFTPREVGNH--FINVYQSGAHILGSPFKIVVGQNEIGDASKVRVFGEGLKCGISNEMNSFTVDTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANEHVSGSPFAVKITGEPSAKLMEKI 2929 The following BLAST results are available for this feature:
BLAST of Filamin A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Filamin A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Filamin A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Filamin A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Filamin A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Filamin A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Filamin A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Filamin A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032338 ID=SMED30032338|Name=Filamin A|organism=Schmidtea mediterranea sexual|type=transcript|length=6014bpback to top protein sequence of SMED30032338-orf-1 >SMED30032338-orf-1 ID=SMED30032338-orf-1|Name=SMED30032338-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1952bp MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|