Filamin A

Overview
NameFilamin A
Smed IDSMED30032338
Length (bp)6014
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Filamin A (SMED30032338) t-SNE clustered cells

Violin plots show distribution of expression levels for Filamin A (SMED30032338) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Filamin A (SMED30032338) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Filamin A (SMED30032338) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30032338

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30032338h1SMcG0012741 Contig43033uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig43033newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig17080uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig17080newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig47411newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig47411uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig29835newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30032338h1SMcG0012741 Contig29835uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755])

HSP 1 Score: 164.081 bits (414), Expect = 1.490e-39
Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++              VE  D  GN  +     +  K+   S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + I    + I  SP+ + + ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482          

HSP 2 Score: 90.8929 bits (224), Expect = 2.592e-17
Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V   +DD  R  +    +  +       N+  S +I+  G    +   V SP      C V+E        P K           +       GV+ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI       +      +L VTI+GPSKV++ C E   GY   Y P+  G Y I + Y    HI GSPFK  V
Sbjct: 2183 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2460          

HSP 3 Score: 83.9593 bits (206), Expect = 3.514e-15
Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD  R           CS+V++ +            + +  +S  ++ +L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1813 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2078          

HSP 4 Score: 82.8037 bits (203), Expect = 7.001e-15
Identity = 88/311 (28.30%), Postives = 128/311 (41.16%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      +     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V  +    V   +  N    KP    + F V   EI      V  P G ++   I       NKDG + V +A T +G++ +    ++G  I  S                           PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVTEEAYVPV---SDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1900          

HSP 5 Score: 72.7886 bits (177), Expect = 8.087e-12
Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +         VK  I           + S+  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1984 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2275          

HSP 6 Score: 71.2478 bits (173), Expect = 2.623e-11
Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P R+ V  A D +R ++    ++  D+  E       +S  +  VG + I  H+++P   +  CFVT+                 N DG           Y +++  F                   L    ++ D D+ I N    + V E  Q   + A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++ V
Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415          

HSP 7 Score: 70.0922 bits (170), Expect = 5.449e-11
Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +F   P   G + I I    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I
Sbjct:  512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636          

HSP 8 Score: 68.1662 bits (165), Expect = 2.473e-10
Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276
            + I N PF+V V    +   + + GPGL  +  + P VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+ + +     V +  KVK+       G+  +  +SF +DS  +    P +V      G+     +V   +  +     P      + V V Y   ++   P+ +     YD+++        S++       ++      +DA +     L V   +      + K+ I+ H+  + +   T+  I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++  ++   T V  + +P+
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717          

HSP 9 Score: 62.3882 bits (150), Expect = 1.295e-8
Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L + F N  N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420          

HSP 10 Score: 62.003 bits (149), Expect = 1.652e-8
Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   ++
Sbjct: 1769 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1902          

HSP 11 Score: 58.9214 bits (141), Expect = 1.570e-7
Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 56.9954 bits (136), Expect = 5.824e-7
Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I +SPY + ++  +  D+ +++ V+ L+    K
Sbjct: 2088 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2290          

HSP 13 Score: 53.9138 bits (128), Expect = 5.132e-6
Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348
            G +G  +EGP E+++ C    DG    ++ P   G Y++ +T  G  I GSPF + V +  D        P   S     V Q  + +S K G  P
Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454          
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755])

HSP 1 Score: 164.081 bits (414), Expect = 1.708e-39
Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++              VE  D  GN  +     +  K+   S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + I    + I  SP+ + + ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482          

HSP 2 Score: 90.8929 bits (224), Expect = 2.683e-17
Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V   +DD  R  +    +  +       N+  S +I+  G    +   V SP      C V+E        P K           +       GV+ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI       +      +L VTI+GPSKV++ C E   GY   Y P+  G Y I + Y    HI GSPFK  V
Sbjct: 2194 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2471          

HSP 3 Score: 83.9593 bits (206), Expect = 3.637e-15
Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD  R           CS+V++ +            + +  +S  ++ +L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089          

HSP 4 Score: 81.6481 bits (200), Expect = 1.722e-14
Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      +     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V       +P +  E  +  +  N    KP    + F V   EI      V  P G ++   I       NKDG + V +A T +G++ +    ++G  I  S                           PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911          

HSP 5 Score: 72.7886 bits (177), Expect = 8.160e-12
Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +         VK  I           + S+  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1995 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2286          

HSP 6 Score: 71.2478 bits (173), Expect = 2.691e-11
Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P R+ V  A D +R ++    ++  D+  E       +S  +  VG + I  H+++P   +  CFVT+                 N DG           Y +++  F                   L    ++ D D+ I N    + V E  Q   + A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++ V
Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415          

HSP 7 Score: 70.0922 bits (170), Expect = 5.782e-11
Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +F   P   G + I I    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I
Sbjct:  512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636          

HSP 8 Score: 67.781 bits (164), Expect = 2.714e-10
Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276
            + I N PF+V V    +   + + GPGL  +  + P VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+ + +     V +  KVK+       G+  +  +SF +DS  +    P +V      G+     +V   +  +     P      + V V Y   ++   P+ +     YD+++        S++       ++      +DA +     L V   +      + K+ I+ H+  + +   T+  I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++  ++   T V  + +P+
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717          

HSP 9 Score: 62.3882 bits (150), Expect = 1.295e-8
Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L + F N  N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420          

HSP 10 Score: 62.003 bits (149), Expect = 1.813e-8
Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   ++
Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1913          

HSP 11 Score: 58.9214 bits (141), Expect = 1.571e-7
Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 56.6102 bits (135), Expect = 6.127e-7
Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I +SPY + ++  +  D+ +++ V+ L+    K
Sbjct: 2099 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2301          

HSP 13 Score: 53.5286 bits (127), Expect = 5.265e-6
Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348
            G +G  +EGP E+++ C    DG    ++ P   G Y++ +T  G  I GSPF + V +  D        P   S     V Q  + +S K G  P
Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454          
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755])

HSP 1 Score: 164.081 bits (414), Expect = 1.775e-39
Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++              VE  D  GN  +     +  K+   S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + I    + I  SP+ + + ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482          

HSP 2 Score: 90.8929 bits (224), Expect = 2.678e-17
Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V   +DD  R  +    +  +       N+  S +I+  G    +   V SP      C V+E        P K           +       GV+ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI       +      +L VTI+GPSKV++ C E   GY   Y P+  G Y I + Y    HI GSPFK  V
Sbjct: 2170 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2447          

HSP 3 Score: 83.9593 bits (206), Expect = 3.571e-15
Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD  R           CS+V++ +            + +  +S  ++ +L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1800 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2065          

HSP 4 Score: 81.6481 bits (200), Expect = 1.967e-14
Identity = 86/311 (27.65%), Postives = 127/311 (40.84%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      +     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF + V ++    +                +  N    KP    + F V   EI      V  P G ++   I       NKDG + V +A T +G++ +    ++G  I  S                           PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPV----------------SDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1887          

HSP 5 Score: 72.7886 bits (177), Expect = 8.082e-12
Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +         VK  I           + S+  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1971 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2262          

HSP 6 Score: 71.2478 bits (173), Expect = 2.666e-11
Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P R+ V  A D +R ++    ++  D+  E       +S  +  VG + I  H+++P   +  CFVT+                 N DG           Y +++  F                   L    ++ D D+ I N    + V E  Q   + A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++ V
Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415          

HSP 7 Score: 70.0922 bits (170), Expect = 5.679e-11
Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +F   P   G + I I    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I
Sbjct:  512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636          

HSP 8 Score: 69.707 bits (169), Expect = 7.007e-11
Identity = 89/413 (21.55%), Postives = 165/413 (39.95%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243
            + I N PF+V V    +   + + GPGL  +  + P VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+ + +     V +  KVK+       G+  +  +SF +DS  +    P +V      G+     +V   +  +     P      + V V Y   ++   P+ +     YD+++        S++       ++      +DA +     L V   +      + K+ I+ H+  + +   T+  I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++ V+E +
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEA 1708          

HSP 9 Score: 62.3882 bits (150), Expect = 1.283e-8
Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L + F N  N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420          

HSP 10 Score: 62.003 bits (149), Expect = 1.766e-8
Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   ++
Sbjct: 1756 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1889          

HSP 11 Score: 58.5362 bits (140), Expect = 1.596e-7
Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 56.9954 bits (136), Expect = 5.970e-7
Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I +SPY + ++  +  D+ +++ V+ L+    K
Sbjct: 2075 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2277          

HSP 13 Score: 53.9138 bits (128), Expect = 5.086e-6
Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348
            G +G  +EGP E+++ C    DG    ++ P   G Y++ +T  G  I GSPF + V +  D        P   S     V Q  + +S K G  P
Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454          
BLAST of Filamin A vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755])

HSP 1 Score: 164.081 bits (414), Expect = 1.836e-39
Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++              VE  D  GN  +     +  K+   S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + I    + I  SP+ + + ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482          

HSP 2 Score: 90.8929 bits (224), Expect = 2.711e-17
Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V   +DD  R  +    +  +       N+  S +I+  G    +   V SP      C V+E        P K           +       GV+ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI       +      +L VTI+GPSKV++ C E   GY   Y P+  G Y I + Y    HI GSPFK  V
Sbjct: 2225 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2502          

HSP 3 Score: 83.9593 bits (206), Expect = 3.644e-15
Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD  R           CS+V++ +            + +  +S  ++ +L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1855 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2120          

HSP 4 Score: 81.6481 bits (200), Expect = 1.725e-14
Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      +     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V       +P +  E  +  +  N    KP    + F V   EI      V  P G ++   I       NKDG + V +A T +G++ +    ++G  I  S                           PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1667 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1942          

HSP 5 Score: 72.7886 bits (177), Expect = 8.173e-12
Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +         VK  I           + S+  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 2026 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2317          

HSP 6 Score: 71.2478 bits (173), Expect = 2.695e-11
Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P R+ V  A D +R ++    ++  D+  E       +S  +  VG + I  H+++P   +  CFVT+                 N DG           Y +++  F                   L    ++ D D+ I N    + V E  Q   + A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++ V
Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415          

HSP 7 Score: 70.0922 bits (170), Expect = 5.647e-11
Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +F   P   G + I I    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I
Sbjct:  512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636          

HSP 8 Score: 62.3882 bits (150), Expect = 1.297e-8
Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L + F N  N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420          

HSP 9 Score: 62.003 bits (149), Expect = 1.484e-8
Identity = 42/143 (29.37%), Postives = 71/143 (49.65%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNS 1532
            + I N PF+V V    +   + + GPGL  +  + P VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+ + +     V +  KVK+       G+  +  +SF +DS  +
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKA 1450          

HSP 10 Score: 61.6178 bits (148), Expect = 1.909e-8
Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   ++
Sbjct: 1811 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1944          

HSP 11 Score: 58.5362 bits (140), Expect = 1.586e-7
Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 56.6102 bits (135), Expect = 6.506e-7
Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I +SPY + ++  +  D+ +++ V+ L+    K
Sbjct: 2130 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2332          

HSP 13 Score: 53.9138 bits (128), Expect = 4.969e-6
Identity = 29/96 (30.21%), Postives = 43/96 (44.79%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTP 2348
            G +G  +EGP E+++ C    DG    ++ P   G Y++ +T  G  I GSPF + V +  D        P   S     V Q  + +S K G  P
Sbjct: 1359 GGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAP 1454          
BLAST of Filamin A vs. Ensembl Human
Match: FLNA (filamin A [Source:HGNC Symbol;Acc:HGNC:3754])

HSP 1 Score: 158.303 bits (399), Expect = 1.029e-37
Identity = 136/514 (26.46%), Postives = 232/514 (45.14%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-------QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
             +  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  + NA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+         Q     +G  + ++E    G+ +   +Y   + G++ + +      I  SPY++ + ++      + V   GL+ K  +
Sbjct:   23 TRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEAR--GDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGR-GLQPKGVR 496          

HSP 2 Score: 106.301 bits (264), Expect = 5.238e-22
Identity = 100/326 (30.67%), Postives = 141/326 (43.25%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +       +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       GVY ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2231 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGVYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGNPAEFVVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508          

HSP 3 Score: 79.7221 bits (195), Expect = 7.576e-14
Identity = 83/327 (25.38%), Postives = 141/327 (43.12%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + + T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD            Y N   + AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y N+ H+PGSPF   V  D +  ++H
Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPTITDNKDGTVTVRYAPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVD------------YVNCGHVTAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKY-NEQHVPGSPFTARVTGDDSMRMSH 1954          

HSP 4 Score: 78.1814 bits (191), Expect = 1.894e-13
Identity = 99/456 (21.71%), Postives = 176/456 (38.60%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLI-IKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +V      ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +        + +  V  R   +  +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VGPSGAAVPCKVEPGLGADNSV-VRFLPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPS----GNLTETYVQDRGDGMYKVEYTPYEEG----LHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.3218 bits (168), Expect = 1.017e-10
Identity = 39/98 (39.80%), Postives = 51/98 (52.04%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            V   G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N+  +P SPF   V  D + R+ H  V
Sbjct: 1860 VTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKV 1957          

HSP 6 Score: 69.3218 bits (168), Expect = 1.088e-10
Identity = 90/345 (26.09%), Postives = 145/345 (42.03%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  VG +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G + +            S K K +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGTHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323          

HSP 7 Score: 65.855 bits (159), Expect = 1.034e-9
Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNS 1532
             F   P++ G++ + I        I   PF V V        + ++GPGL G V      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I  + +     +VK    GLE           F +D+++ 
Sbjct:  539 GFEYYPMVPGTYIVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHG 702          

HSP 8 Score: 60.8474 bits (146), Expect = 3.215e-8
Identity = 35/132 (26.52%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    + +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  NE+++  SP++  +
Sbjct: 1816 KDGTVTVRYAPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARV 1944          

HSP 9 Score: 56.9954 bits (136), Expect = 4.809e-7
Identity = 58/218 (26.61%), Postives = 94/218 (43.12%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  F+++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK+       +    P D       G+  +   V   +K  F ++C       L+V V
Sbjct: 2378 DKYAVRFIPRENGVYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVG--QKSSFTVDCSKAGNNMLLVGV 2586          

HSP 10 Score: 54.299 bits (129), Expect = 3.184e-6
Identity = 67/295 (22.71%), Postives = 121/295 (41.02%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDG-RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIE-CPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEG 1739
            I +  + P V   G   DL +KIP I     +++  +    +G  ++        +++      +P   G+  + +K       +   PF+  V    +     + + GPGL  + A  P  F I         +  ++EGPSK +I   +  +GS  + Y    PG Y++S+  NEE+I DSP+ +V V S   D     +  ++  GL+     SF +    +   +  D +     G +     VTE+++  + +   P  N   LI  V +    + G P+ I   +   G
Sbjct: 2136 ITRRRRAPSVANVGSHCDLSLKIPEIS---IQDMTAQVTSPSGKTHEAEIV--EGENHTYCIRFVPAEMGTHTVSVKYK--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPF-VVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAI--DAKVHSPSG-ALEECYVTEIDQDKYAVRFIPRENGVYLI-DVKFNGTHIPGSPFKIRVGEPGHG 2418          
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09])

HSP 1 Score: 127.872 bits (320), Expect = 3.653e-29
Identity = 72/227 (31.72%), Postives = 120/227 (52.86%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSG 752
            I++  FTRW+ + L+   + I  L+ D  +G  L+ L ++LS K +    +K+ F +Q  ++    LN    F   E +++ NI+   I+D + K I  L+W LI HYSI       K   G+N  +   +  LNW+ ++L G  I N +S WN G+A+G +VN+       D   W+ ++AL N + AM++A     +  L+ P E+I     + ++MTY+SQF  
Sbjct:   27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPA 250          

HSP 2 Score: 73.9442 bits (180), Expect = 1.058e-12
Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3
Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568
            P     I ++G GL G + + P VF ++ NG  + + F++EGPSK +I C    +GS +++Y+  + G+Y++ ++ + ++I DSP+ + + +  +  +    +V G++     +      F +D+R    ++ P VE  D
Sbjct:  543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682          

HSP 3 Score: 52.373 bits (124), Expect = 4.404e-6
Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            D++ + +   + F +EGP + ++ C  + DG  I+ + P  AG Y++ V  DGK I  SPF + V+E
Sbjct:  568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634          
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09])

HSP 1 Score: 128.257 bits (321), Expect = 4.564e-29
Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I++  FTRW+ + L+   + I  L+ D  +G  L+ L ++LS K +    +K+ F +Q  ++    LN    F   E +++ NI+   I+D + K I  L+W LI HYSI       K   G+N  +   +  LNW+ ++L G  I N +S WN G+A+G +VN+       D   W+ ++AL N + AM++A     +  L+ P E+I     + ++MTY+SQF
Sbjct:   27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248          

HSP 2 Score: 73.9442 bits (180), Expect = 1.280e-12
Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3
Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568
            P     I ++G GL G + + P VF ++ NG  + + F++EGPSK +I C    +GS +++Y+  + G+Y++ ++ + ++I DSP+ + + +  +  +    +V G++     +      F +D+R    ++ P VE  D
Sbjct:  543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682          

HSP 3 Score: 67.3958 bits (163), Expect = 1.305e-10
Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174
            ++V   G+ + +G     N F ++      G +A+ IEGPSKA + F D   G   V Y+V  PGEYV A+ FN   IP SPF++ +A
Sbjct: 1851 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1938          

HSP 4 Score: 60.077 bits (144), Expect = 2.583e-8
Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            I A GDGL + T  +K  F I   N    I      L V +DGPSK  +   E   GY   Y P+  G YF  + Y N  H PGSPFKI V
Sbjct: 2044 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2127          

HSP 5 Score: 59.6918 bits (143), Expect = 2.882e-8
Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3
Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            V G  L    V     F V   G     L++ IEGP+K++I   D K G    ++   +PGEY   +      +  SPFR+ V  +  +R    H+     SEV     + + KG S SIK           SP  +   CFV    GG    SF P +      T  +DG +   A          +    DK  +G + KV++    G  +  TL              NE+  +    G G                             L V++ GPSK +++C E  +G I   Y P   G+Y I I +++  H+  SP  +
Sbjct: 1481 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1742          

HSP 6 Score: 55.4546 bits (132), Expect = 6.250e-7
Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201
            KT+ GD S++  EV   GKA  KG     N+ +V TS    G L++ ++GPSKAE++  + K G+  V Y  T PG Y  AI F    +  SP  +        R++ 
Sbjct: 1651 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1754          

HSP 7 Score: 53.9138 bits (128), Expect = 1.895e-6
Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171
            I V  +   + + P+ + V GK LC             KG      +FV++T+    G L + ++GPSKA +   + + G Y V Y    PG Y  ++ +N +  P SPF+I V
Sbjct: 2015 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2127          

HSP 8 Score: 53.5286 bits (127), Expect = 2.150e-6
Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547
            +YGPGL  +V     VF LD +G+ +  +   M GP+K +    + GNG   + Y A  PG Y+++I       +E++  SP+  V+   +   +  ++ + GL+  N +     +F+ID+ + T ++P
Sbjct:  931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055          

HSP 9 Score: 52.7582 bits (125), Expect = 4.073e-6
Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439
            P + GS ++ I +N    ++   P +  V+        V YGPGL  +V   P  F +   GS  +++  S+EGP+K++I+  +  +G+    +   +PG Y++ + +  + + DSP+ ++++
Sbjct: 1445 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1564          

HSP 10 Score: 51.9878 bits (123), Expect = 6.521e-6
Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            D++ + +   + F +EGP + ++ C  + DG  I+ + P  AG Y++ V  DGK I  SPF + V+E
Sbjct:  568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634          
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09])

HSP 1 Score: 128.257 bits (321), Expect = 4.842e-29
Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I++  FTRW+ + L+   + I  L+ D  +G  L+ L ++LS K +    +K+ F +Q  ++    LN    F   E +++ NI+   I+D + K I  L+W LI HYSI       K   G+N  +   +  LNW+ ++L G  I N +S WN G+A+G +VN+       D   W+ ++AL N + AM++A     +  L+ P E+I     + ++MTY+SQF
Sbjct:   27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248          

HSP 2 Score: 73.9442 bits (180), Expect = 1.324e-12
Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3
Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568
            P     I ++G GL G + + P VF ++ NG  + + F++EGPSK +I C    +GS +++Y+  + G+Y++ ++ + ++I DSP+ + + +  +  +    +V G++     +      F +D+R    ++ P VE  D
Sbjct:  543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682          

HSP 3 Score: 67.3958 bits (163), Expect = 1.305e-10
Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174
            ++V   G+ + +G     N F ++      G +A+ IEGPSKA + F D   G   V Y+V  PGEYV A+ FN   IP SPF++ +A
Sbjct: 1853 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1940          

HSP 4 Score: 60.077 bits (144), Expect = 2.562e-8
Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            I A GDGL + T  +K  F I   N    I      L V +DGPSK  +   E   GY   Y P+  G YF  + Y N  H PGSPFKI V
Sbjct: 2046 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2129          

HSP 5 Score: 59.6918 bits (143), Expect = 2.882e-8
Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3
Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            V G  L    V     F V   G     L++ IEGP+K++I   D K G    ++   +PGEY   +      +  SPFR+ V  +  +R    H+     SEV     + + KG S SIK           SP  +   CFV    GG    SF P +      T  +DG +   A          +    DK  +G + KV++    G  +  TL              NE+  +    G G                             L V++ GPSK +++C E  +G I   Y P   G+Y I I +++  H+  SP  +
Sbjct: 1483 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1744          

HSP 6 Score: 55.4546 bits (132), Expect = 6.250e-7
Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201
            KT+ GD S++  EV   GKA  KG     N+ +V TS    G L++ ++GPSKAE++  + K G+  V Y  T PG Y  AI F    +  SP  +        R++ 
Sbjct: 1653 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1756          

HSP 7 Score: 53.9138 bits (128), Expect = 1.896e-6
Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171
            I V  +   + + P+ + V GK LC             KG      +FV++T+    G L + ++GPSKA +   + + G Y V Y    PG Y  ++ +N +  P SPF+I V
Sbjct: 2017 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2129          

HSP 8 Score: 53.5286 bits (127), Expect = 2.205e-6
Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547
            +YGPGL  +V     VF LD +G+ +  +   M GP+K +    + GNG   + Y A  PG Y+++I       +E++  SP+  V+   +   +  ++ + GL+  N +     +F+ID+ + T ++P
Sbjct:  931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055          

HSP 9 Score: 52.7582 bits (125), Expect = 4.039e-6
Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439
            P + GS ++ I +N    ++   P +  V+        V YGPGL  +V   P  F +   GS  +++  S+EGP+K++I+  +  +G+    +   +PG Y++ + +  + + DSP+ ++++
Sbjct: 1447 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1566          

HSP 10 Score: 51.9878 bits (123), Expect = 6.688e-6
Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            D++ + +   + F +EGP + ++ C  + DG  I+ + P  AG Y++ V  DGK I  SPF + V+E
Sbjct:  568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634          
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09])

HSP 1 Score: 127.872 bits (320), Expect = 5.313e-29
Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I++  FTRW+ + L+   + I  L+ D  +G  L+ L ++LS K +    +K+ F +Q  ++    LN    F   E +++ NI+   I+D + K I  L+W LI HYSI       K   G+N  +   +  LNW+ ++L G  I N +S WN G+A+G +VN+       D   W+ ++AL N + AM++A     +  L+ P E+I     + ++MTY+SQF
Sbjct:   27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248          

HSP 2 Score: 74.3294 bits (181), Expect = 1.133e-12
Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3
Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568
            P     I ++G GL G + + P VF ++ NG  + + F++EGPSK +I C    +GS +++Y+  + G+Y++ ++ + ++I DSP+ + + +  +  +    +V G++     +      F +D+R    ++ P VE  D
Sbjct:  543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682          

HSP 3 Score: 67.3958 bits (163), Expect = 1.258e-10
Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174
            ++V   G+ + +G     N F ++      G +A+ IEGPSKA + F D   G   V Y+V  PGEYV A+ FN   IP SPF++ +A
Sbjct: 1800 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1887          

HSP 4 Score: 60.077 bits (144), Expect = 2.512e-8
Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            I A GDGL + T  +K  F I   N    I      L V +DGPSK  +   E   GY   Y P+  G YF  + Y N  H PGSPFKI V
Sbjct: 1993 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2076          

HSP 5 Score: 59.6918 bits (143), Expect = 2.710e-8
Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3
Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            V G  L    V     F V   G     L++ IEGP+K++I   D K G    ++   +PGEY   +      +  SPFR+ V  +  +R    H+     SEV     + + KG S SIK           SP  +   CFV    GG    SF P +      T  +DG +   A          +    DK  +G + KV++    G  +  TL              NE+  +    G G                             L V++ GPSK +++C E  +G I   Y P   G+Y I I +++  H+  SP  +
Sbjct: 1430 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1691          

HSP 6 Score: 55.4546 bits (132), Expect = 6.028e-7
Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201
            KT+ GD S++  EV   GKA  KG     N+ +V TS    G L++ ++GPSKAE++  + K G+  V Y  T PG Y  AI F    +  SP  +        R++ 
Sbjct: 1600 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1703          

HSP 7 Score: 53.9138 bits (128), Expect = 1.768e-6
Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171
            I V  +   + + P+ + V GK LC             KG      +FV++T+    G L + ++GPSKA +   + + G Y V Y    PG Y  ++ +N +  P SPF+I V
Sbjct: 1964 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2076          

HSP 8 Score: 53.5286 bits (127), Expect = 2.200e-6
Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547
            +YGPGL  +V     VF LD +G+ +  +   M GP+K +    + GNG   + Y A  PG Y+++I       +E++  SP+  V+   +   +  ++ + GL+  N +     +F+ID+ + T ++P
Sbjct:  931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055          

HSP 9 Score: 52.7582 bits (125), Expect = 4.029e-6
Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439
            P + GS ++ I +N    ++   P +  V+        V YGPGL  +V   P  F +   GS  +++  S+EGP+K++I+  +  +G+    +   +PG Y++ + +  + + DSP+ ++++
Sbjct: 1394 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1513          

HSP 10 Score: 51.9878 bits (123), Expect = 6.617e-6
Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            D++ + +   + F +EGP + ++ C  + DG  I+ + P  AG Y++ V  DGK I  SPF + V+E
Sbjct:  568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634          
BLAST of Filamin A vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09])

HSP 1 Score: 127.872 bits (320), Expect = 5.497e-29
Identity = 72/225 (32.00%), Postives = 120/225 (53.33%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSI-------KTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I++  FTRW+ + L+   + I  L+ D  +G  L+ L ++LS K +    +K+ F +Q  ++    LN    F   E +++ NI+   I+D + K I  L+W LI HYSI       K   G+N  +   +  LNW+ ++L G  I N +S WN G+A+G +VN+       D   W+ ++AL N + AM++A     +  L+ P E+I     + ++MTY+SQF
Sbjct:   27 IQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALN---FFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMGWIQEKREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQF 248          

HSP 2 Score: 74.3294 bits (181), Expect = 1.134e-12
Identity = 37/140 (26.43%), Postives = 76/140 (54.29%), Query Frame = 3
Query: 1167 PNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS------FIIDSRNSTFEMPPDVECFD 1568
            P     I ++G GL G + + P VF ++ NG  + + F++EGPSK +I C    +GS +++Y+  + G+Y++ ++ + ++I DSP+ + + +  +  +    +V G++     +      F +D+R    ++ P VE  D
Sbjct:  543 PESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILD 682          

HSP 3 Score: 67.3958 bits (163), Expect = 1.268e-10
Identity = 34/88 (38.64%), Postives = 49/88 (55.68%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA 5174
            ++V   G+ + +G     N F ++      G +A+ IEGPSKA + F D   G   V Y+V  PGEYV A+ FN   IP SPF++ +A
Sbjct: 1802 HKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIA 1889          

HSP 4 Score: 60.077 bits (144), Expect = 2.512e-8
Identity = 38/91 (41.76%), Postives = 44/91 (48.35%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            I A GDGL + T  +K  F I   N    I      L V +DGPSK  +   E   GY   Y P+  G YF  + Y N  H PGSPFKI V
Sbjct: 1995 ISASGDGLVKGTTGQKCEFVINTANAGAGI------LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKY-NGIHAPGSPFKIPV 2078          

HSP 5 Score: 59.6918 bits (143), Expect = 2.733e-8
Identity = 82/327 (25.08%), Postives = 122/327 (37.31%), Query Frame = 3
Query: 4923 VIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEV-----EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGS---SFHPIKKMSK--TSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            V G  L    V     F V   G     L++ IEGP+K++I   D K G    ++   +PGEY   +      +  SPFR+ V  +  +R    H+     SEV     + + KG S SIK           SP  +   CFV    GG    SF P +      T  +DG +   A          +    DK  +G + KV++    G  +  TL              NE+  +    G G                             L V++ GPSK +++C E  +G I   Y P   G+Y I I +++  H+  SP  +
Sbjct: 1432 VYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKR---SHLSVGSTSEVALPITQQELKGISASIK-----------SPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAP---------FKIKVDKTQVGDASKVEVSG-SGKAKGITLQ------------ANELLVDTSKAGYG----------------------------GLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADH-HVKDSPLTV 1693          

HSP 6 Score: 55.4546 bits (132), Expect = 6.028e-7
Identity = 38/108 (35.19%), Postives = 55/108 (50.93%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILH 5201
            KT+ GD S++  EV   GKA  KG     N+ +V TS    G L++ ++GPSKAE++  + K G+  V Y  T PG Y  AI F    +  SP  +        R++ 
Sbjct: 1602 KTQVGDASKV--EVSGSGKA--KGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQ 1705          

HSP 7 Score: 53.9138 bits (128), Expect = 1.768e-6
Identity = 34/114 (29.82%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALC-------------KGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171
            I V  +   + + P+ + V GK LC             KG      +FV++T+    G L + ++GPSKA +   + + G Y V Y    PG Y  ++ +N +  P SPF+I V
Sbjct: 1966 IHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPV 2078          

HSP 8 Score: 53.5286 bits (127), Expect = 2.200e-6
Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 1191 SYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVN----EENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMP 1547
            +YGPGL  +V     VF LD +G+ +  +   M GP+K +    + GNG   + Y A  PG Y+++I       +E++  SP+  V+   +   +  ++ + GL+  N +     +F+ID+ + T ++P
Sbjct:  931 AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV---DYKKDPSQITISGLDQPNYRLNQPINFVIDT-SKTKDLP 1055          

HSP 9 Score: 52.7582 bits (125), Expect = 3.996e-6
Identity = 31/123 (25.20%), Postives = 65/123 (52.85%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439
            P + GS ++ I +N    ++   P +  V+        V YGPGL  +V   P  F +   GS  +++  S+EGP+K++I+  +  +G+    +   +PG Y++ + +  + + DSP+ ++++
Sbjct: 1396 PKVHGSHELSILQN--GAQLQGTPIKFYVDAYGDGWATV-YGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM 1515          

HSP 10 Score: 51.9878 bits (123), Expect = 6.562e-6
Identity = 23/67 (34.33%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 2037 DLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            D++ + +   + F +EGP + ++ C  + DG  I+ + P  AG Y++ V  DGK I  SPF + V+E
Sbjct:  568 DVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTE 634          
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0089471)

HSP 1 Score: 154.451 bits (389), Expect = 5.877e-37
Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3
Query:   63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            E +R  +E  +  KI++  FTRW N  LK  ++ I +L+ DL +G  L+ LIE+LSQK++ K       R  ++  ++  L FL+ EG+++ NI+  DI+D  +K I  L+W LI HYSI   +  GE++    G      +  LNW+++K+    I+N ++ W +G A+G +V+ C   LC D   W+  +A+ NA  AM  A     + QL+KP E+++ +  ++++MTY+SQ+        + L  + N N+    G  +  +    G      A  + +  S                G VD+ I+ P                 NG + K     N  K+   + S IP   GS  + +K +    +I   PF V V       + V   GPG+  +          D    D   G     +  P+  K   A     + N +    Y   L G++ +++      I +SP+    VK   + + +KV+  G   + T   + D  +         E  P+V      G+ + N++ ++++   +          R ++ V +   +V   P+ +
Sbjct:    2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542          

HSP 2 Score: 112.464 bits (280), Expect = 4.022e-24
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            G  L +G V    +F V T     G+LAI +EGPSKA+I F D+K G   VSY+VT PGEY   + FN   IP SPF++ V+ D      HK        EV+   +GN  +  P    +  + +  E   L+  +  P G             ++ D FI V    +  Y++ FY    +    +  VK   +H  +  +     V   + +P  V+       A G+GL +     K  F I   N          +L V+IDGPSKV + C E   GY   Y P++ G ++I + Y+N  HI GSPFK+    D  +D   QE
Sbjct: 1811 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2091          

HSP 3 Score: 91.6633 bits (226), Expect = 6.965e-18
Identity = 113/469 (24.09%), Postives = 190/469 (40.51%), Query Frame = 3
Query:  972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTK--KLIIKHETFEESQLKT----FKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246
            +N++   VD  GN Y+C    ++  + E  + ++   +G             E+   PF V V  P K+ +IV+YGPGL   V   P  F+++TNG    +GF++ GPS+ +IEC + G+GS L+ Y     G Y + I+ + E+I  SP+ + ++ +++   E+ K    GLE          SF +D   +    P DV   D  G        NN   T+             +E  Y  +  P N+  R+ V V     +V+ F         P A     +D  ++ + + KV      + ++  C  I N+D   ++E+        T        R    + ++  +T + S++K        I       +   S  G  I  G+      D         +G VL   I   VQ     D  + I + P  AG++ + +  D   + GSPF + V    D
Sbjct:  500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGEKVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD--------PMGHVLPSKI---VQ--GPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCD 934          

HSP 4 Score: 79.7221 bits (195), Expect = 2.857e-14
Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G       F + T G   G L + +EGPSKA+I++ D K G   V Y  T PGEY  ++ F    I  SP+   +  +  +R     +    CSEV M        ++ +  +    + +P  L   CF+   P G  G SF P         +K++ K  N   F                     ++G + KVK+                                    G GL++   +  N F +   N           L V+I+GPSK +I C +  +G +   Y P   G Y + + +++  H+ GSPF + V
Sbjct: 1431 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1698          

HSP 5 Score: 73.9442 bits (180), Expect = 1.883e-12
Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +V V G  L +G  + +N F V T     G L++ IEGPSKAEI   DK  G   +SY+ T PG Y+  + F    +  SPF + VA + + R   K           +Q + ++  I  +G    L F +      +L   VT P   +    I+++     +DG   ++     +GV+ +            S +    +I GS    T         + PL  +     + A G GL++  V     F +  W           SL ++++GPSK  I   +  +G     Y     G Y +G+ ++++ HIP SPFK+ V  D
Sbjct: 1613 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 1894          

HSP 6 Score: 70.8626 bits (172), Expect = 1.382e-11
Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P      G  L KG  N  NKF V T G   G L++ IEGPS+A+++  D + G   V Y  T PGEY   I F    IP SPFR+ V + V+
Sbjct:  935 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1027          

HSP 7 Score: 57.3806 bits (137), Expect = 1.671e-7
Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            N+  E    +G V K     N  +   +S    P   GS ++ +K N     +   PF+  V+       + +YGPGL   V   P  F + T G S   +  ++EGPSK  I   +  +G+V + Y    PG YQ+S+   +++I  SPY
Sbjct: 1366 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1511          

HSP 8 Score: 55.0694 bits (131), Expect = 8.463e-7
Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            I V     ++++ P+EV V           G  L  G + +   FVV T+G+  G L   + GPS+AEI   D   G  +V Y  T  GEY   I  +  DIP SPF
Sbjct:  526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631          

HSP 9 Score: 53.1434 bits (126), Expect = 3.779e-6
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PF V V          +YGPGL   + +    F ++T G+ +  +  ++EGPS+ K+ C +  +GS  + Y A  PG Y ++I   +++I  SP+ +++ ++  VD   KVKV G
Sbjct:  918 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1035          
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337101)

HSP 1 Score: 154.451 bits (389), Expect = 7.308e-37
Identity = 143/585 (24.44%), Postives = 254/585 (43.42%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            ++  E +R  +E  +  KI++  FTRW N  LK  ++ I +L+ DL +G  L+ LIE+LSQK++ K       R  ++  ++  L FL+ EG+++ NI+  DI+D  +K I  L+W LI HYSI   +  GE++    G      +  LNW+++K+    I+N ++ W +G A+G +V+ C   LC D   W+  +A+ NA  AM  A     + QL+KP E+++ +  ++++MTY+SQ+        + L  + N N+    G  +  +    G      A  + +  S                G VD+ I+ P                 NG + K     N  K+   + S IP   GS  + +K +    +I   PF V V       + V   GPG+  +          D    D   G     +  P+  K   A     + N +    Y   L G++ +++      I +SP+    VK   + + +KV+  G   + T   + D  +         E  P+V      G+ + N++ ++++   +          R ++ V +   +V   P+ +
Sbjct:   28 DEDMEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 572          

HSP 2 Score: 112.849 bits (281), Expect = 3.127e-24
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            G  L +G V    +F V T     G+LAI +EGPSKA+I F D+K G   VSY+VT PGEY   + FN   IP SPF++ V+ D      HK        EV+   +GN  +  P    +  + +  E   L+  +  P G             ++ D FI V    +  Y++ FY    +    +  VK   +H  +  +     V   + +P  V+       A G+GL +     K  F I   N          +L V+IDGPSKV + C E   GY   Y P++ G ++I + Y+N  HI GSPFK+    D  +D   QE
Sbjct: 2030 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2310          

HSP 3 Score: 90.5077 bits (223), Expect = 1.837e-17
Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3
Query:  972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832
            +N++   VD  GN Y+C    ++  + E  + ++   +G             E+   PF V V  P K+ +IV+YGPGL   V   P  F+++TNG    +GF++ GPS+ +IEC + G+GS L+ Y     G Y + I+ + E+I  SP+ + ++ +++   E+ K    GLE          SF +D   +    P DV   D  G        NN   T+             +E  Y  +  P N+  R+ V V     +V+ F         P A     +D  ++ + + KV      + ++  C  I N+D   ++E+
Sbjct:  530 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 833          

HSP 4 Score: 80.1073 bits (196), Expect = 2.238e-14
Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G       F + T G   G L + +EGPSKA+I++ D K G   V Y  T PGEY  ++ F    I  SP+   +  +  +R     +    CSEV M        ++ +  +    + +P  L   CF+   P G  G SF P         +K++ K  N   F                     ++G + KVK+                                    G GL++   +  N F +   N           L V+I+GPSK +I C +  +G +   Y P   G Y + + +++  H+ GSPF + V
Sbjct: 1650 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1917          

HSP 5 Score: 74.3294 bits (181), Expect = 1.588e-12
Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +V V G  L +G  + +N F V T     G L++ IEGPSKAEI   DK  G   +SY+ T PG Y+  + F    +  SPF + VA + + R   K           +Q + ++  I  +G    L F +      +L   VT P   +    I+++     +DG   ++     +GV+ +            S +    +I GS    T         + PL  +     + A G GL++  V     F +  W           SL ++++GPSK  I   +  +G     Y     G Y +G+ ++++ HIP SPFK+ V  D
Sbjct: 1832 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2113          

HSP 6 Score: 71.2478 bits (173), Expect = 1.267e-11
Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P      G  L KG  N  NKF V T G   G L++ IEGPS+A+++  D + G   V Y  T PGEY   I F    IP SPFR+ V + V+
Sbjct: 1154 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1246          

HSP 7 Score: 65.0846 bits (157), Expect = 7.987e-10
Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718
            I  +PFR+     +    + ++GPGL   +   P  F++DT G+ Q  +G ++EGP +  I C + G+G+  + Y     G Y ++I  NE +I  SP+  +IV    V  +K  +V  IG++           F++D S+  +      + C  FD +G    + +V       FRI      A R  + + Y  + V G P+ ++
Sbjct:  944 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1147          

HSP 8 Score: 57.3806 bits (137), Expect = 2.136e-7
Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            N+  E    +G V K     N  +   +S    P   GS ++ +K N     +   PF+  V+       + +YGPGL   V   P  F + T G S   +  ++EGPSK  I   +  +G+V + Y    PG YQ+S+   +++I  SPY
Sbjct: 1585 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1730          

HSP 9 Score: 55.4546 bits (132), Expect = 7.992e-7
Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            I V     ++++ P+EV V           G  L  G + +   FVV T+G+  G L   + GPS+AEI   D   G  +V Y  T  GEY   I  +  DIP SPF
Sbjct:  556 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 661          

HSP 10 Score: 52.7582 bits (125), Expect = 4.291e-6
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PF V V          +YGPGL   + +    F ++T G+ +  +  ++EGPS+ K+ C +  +GS  + Y A  PG Y ++I   +++I  SP+ +++ ++  VD   KVKV G
Sbjct: 1137 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1254          

HSP 11 Score: 51.6026 bits (122), Expect = 9.943e-6
Identity = 33/104 (31.73%), Postives = 52/104 (50.00%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFR---ITVADDVNRRILHKHVKP 5216
            +V   G  L +G V    +F++ T G   G L + +EGP +A I+  D   G   V+Y  T  G+Y   I+FN+  I  SPF+   + V +  N R+    ++P
Sbjct:  961 KVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPVPNLKNTRVSGIGIQP 1064          
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0303364)

HSP 1 Score: 154.066 bits (388), Expect = 8.641e-37
Identity = 143/585 (24.44%), Postives = 254/585 (43.42%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            ++  E +R  +E  +  KI++  FTRW N  LK  ++ I +L+ DL +G  L+ LIE+LSQK++ K       R  ++  ++  L FL+ EG+++ NI+  DI+D  +K I  L+W LI HYSI   +  GE++    G      +  LNW+++K+    I+N ++ W +G A+G +V+ C   LC D   W+  +A+ NA  AM  A     + QL+KP E+++ +  ++++MTY+SQ+        + L  + N N+    G  +  +    G      A  + +  S                G VD+ I+ P                 NG + K     N  K+   + S IP   GS  + +K +    +I   PF V V       + V   GPG+  +          D    D   G     +  P+  K   A     + N +    Y   L G++ +++      I +SP+    VK   + + +KV+  G   + T   + D  +         E  P+V      G+ + N++ ++++   +          R ++ V +   +V   P+ +
Sbjct:   28 DEDMEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 572          

HSP 2 Score: 112.464 bits (280), Expect = 3.839e-24
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            G  L +G V    +F V T     G+LAI +EGPSKA+I F D+K G   VSY+VT PGEY   + FN   IP SPF++ V+ D      HK        EV+   +GN  +  P    +  + +  E   L+  +  P G             ++ D FI V    +  Y++ FY    +    +  VK   +H  +  +     V   + +P  V+       A G+GL +     K  F I   N          +L V+IDGPSKV + C E   GY   Y P++ G ++I + Y+N  HI GSPFK+    D  +D   QE
Sbjct: 1841 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2121          

HSP 3 Score: 91.2781 bits (225), Expect = 1.073e-17
Identity = 113/469 (24.09%), Postives = 190/469 (40.51%), Query Frame = 3
Query:  972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTK--KLIIKHETFEESQLKT----FKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246
            +N++   VD  GN Y+C    ++  + E  + ++   +G             E+   PF V V  P K+ +IV+YGPGL   V   P  F+++TNG    +GF++ GPS+ +IEC + G+GS L+ Y     G Y + I+ + E+I  SP+ + ++ +++   E+ K    GLE          SF +D   +    P DV   D  G        NN   T+             +E  Y  +  P N+  R+ V V     +V+ F         P A     +D  ++ + + KV      + ++  C  I N+D   ++E+        T        R    + ++  +T + S++K        I       +   S  G  I  G+      D         +G VL   I   VQ     D  + I + P  AG++ + +  D   + GSPF + V    D
Sbjct:  530 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGEKVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD--------PMGHVLPSKI---VQ--GPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCD 964          

HSP 4 Score: 79.7221 bits (195), Expect = 2.817e-14
Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G       F + T G   G L + +EGPSKA+I++ D K G   V Y  T PGEY  ++ F    I  SP+   +  +  +R     +    CSEV M        ++ +  +    + +P  L   CF+   P G  G SF P         +K++ K  N   F                     ++G + KVK+                                    G GL++   +  N F +   N           L V+I+GPSK +I C +  +G +   Y P   G Y + + +++  H+ GSPF + V
Sbjct: 1461 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1728          

HSP 5 Score: 73.9442 bits (180), Expect = 1.825e-12
Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +V V G  L +G  + +N F V T     G L++ IEGPSKAEI   DK  G   +SY+ T PG Y+  + F    +  SPF + VA + + R   K           +Q + ++  I  +G    L F +      +L   VT P   +    I+++     +DG   ++     +GV+ +            S +    +I GS    T         + PL  +     + A G GL++  V     F +  W           SL ++++GPSK  I   +  +G     Y     G Y +G+ ++++ HIP SPFK+ V  D
Sbjct: 1643 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 1924          

HSP 6 Score: 70.8626 bits (172), Expect = 1.373e-11
Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P      G  L KG  N  NKF V T G   G L++ IEGPS+A+++  D + G   V Y  T PGEY   I F    IP SPFR+ V + V+
Sbjct:  965 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1057          

HSP 7 Score: 57.3806 bits (137), Expect = 1.760e-7
Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            N+  E    +G V K     N  +   +S    P   GS ++ +K N     +   PF+  V+       + +YGPGL   V   P  F + T G S   +  ++EGPSK  I   +  +G+V + Y    PG YQ+S+   +++I  SPY
Sbjct: 1396 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1541          

HSP 8 Score: 55.4546 bits (132), Expect = 8.335e-7
Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            I V     ++++ P+EV V           G  L  G + +   FVV T+G+  G L   + GPS+AEI   D   G  +V Y  T  GEY   I  +  DIP SPF
Sbjct:  556 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 661          

HSP 9 Score: 53.1434 bits (126), Expect = 3.914e-6
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PF V V          +YGPGL   + +    F ++T G+ +  +  ++EGPS+ K+ C +  +GS  + Y A  PG Y ++I   +++I  SP+ +++ ++  VD   KVKV G
Sbjct:  948 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1065          
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0290014)

HSP 1 Score: 153.68 bits (387), Expect = 1.156e-36
Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3
Query:   63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            E +R  +E  +  KI++  FTRW N  LK  ++ I +L+ DL +G  L+ LIE+LSQK++ K       R  ++  ++  L FL+ EG+++ NI+  DI+D  +K I  L+W LI HYSI   +  GE++    G      +  LNW+++K+    I+N ++ W +G A+G +V+ C   LC D   W+  +A+ NA  AM  A     + QL+KP E+++ +  ++++MTY+SQ+        + L  + N N+    G  +  +    G      A  + +  S                G VD+ I+ P                 NG + K     N  K+   + S IP   GS  + +K +    +I   PF V V       + V   GPG+  +          D    D   G     +  P+  K   A     + N +    Y   L G++ +++      I +SP+    VK   + + +KV+  G   + T   + D  +         E  P+V      G+ + N++ ++++   +          R ++ V +   +V   P+ +
Sbjct:    2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542          

HSP 2 Score: 112.849 bits (281), Expect = 3.143e-24
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            G  L +G V    +F V T     G+LAI +EGPSKA+I F D+K G   VSY+VT PGEY   + FN   IP SPF++ V+ D      HK        EV+   +GN  +  P    +  + +  E   L+  +  P G             ++ D FI V    +  Y++ FY    +    +  VK   +H  +  +     V   + +P  V+       A G+GL +     K  F I   N          +L V+IDGPSKV + C E   GY   Y P++ G ++I + Y+N  HI GSPFK+    D  +D   QE
Sbjct: 2000 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2280          

HSP 3 Score: 90.1225 bits (222), Expect = 2.339e-17
Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3
Query:  972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832
            +N++   VD  GN Y+C    ++  + E  + ++   +G             E+   PF V V  P K+ +IV+YGPGL   V   P  F+++TNG    +GF++ GPS+ +IEC + G+GS L+ Y     G Y + I+ + E+I  SP+ + ++ +++   E+ K    GLE          SF +D   +    P DV   D  G        NN   T+             +E  Y  +  P N+  R+ V V     +V+ F         P A     +D  ++ + + KV      + ++  C  I N+D   ++E+
Sbjct:  500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 803          

HSP 4 Score: 80.1073 bits (196), Expect = 2.290e-14
Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G       F + T G   G L + +EGPSKA+I++ D K G   V Y  T PGEY  ++ F    I  SP+   +  +  +R     +    CSEV M        ++ +  +    + +P  L   CF+   P G  G SF P         +K++ K  N   F                     ++G + KVK+                                    G GL++   +  N F +   N           L V+I+GPSK +I C +  +G +   Y P   G Y + + +++  H+ GSPF + V
Sbjct: 1620 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1887          

HSP 5 Score: 74.3294 bits (181), Expect = 1.559e-12
Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +V V G  L +G  + +N F V T     G L++ IEGPSKAEI   DK  G   +SY+ T PG Y+  + F    +  SPF + VA + + R   K           +Q + ++  I  +G    L F +      +L   VT P   +    I+++     +DG   ++     +GV+ +            S +    +I GS    T         + PL  +     + A G GL++  V     F +  W           SL ++++GPSK  I   +  +G     Y     G Y +G+ ++++ HIP SPFK+ V  D
Sbjct: 1802 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2083          

HSP 6 Score: 71.2478 bits (173), Expect = 1.265e-11
Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P      G  L KG  N  NKF V T G   G L++ IEGPS+A+++  D + G   V Y  T PGEY   I F    IP SPFR+ V + V+
Sbjct: 1124 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1216          

HSP 7 Score: 65.0846 bits (157), Expect = 1.001e-9
Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718
            I  +PFR+     +    + ++GPGL   +   P  F++DT G+ Q  +G ++EGP +  I C + G+G+  + Y     G Y ++I  NE +I  SP+  +IV    V  +K  +V  IG++           F++D S+  +      + C  FD +G    + +V       FRI      A R  + + Y  + V G P+ ++
Sbjct:  914 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1117          

HSP 8 Score: 56.9954 bits (136), Expect = 2.588e-7
Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            N+  E    +G V K     N  +   +S    P   GS ++ +K N     +   PF+  V+       + +YGPGL   V   P  F + T G S   +  ++EGPSK  I   +  +G+V + Y    PG YQ+S+   +++I  SPY
Sbjct: 1555 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1700          

HSP 9 Score: 55.4546 bits (132), Expect = 7.982e-7
Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            I V     ++++ P+EV V           G  L  G + +   FVV T+G+  G L   + GPS+AEI   D   G  +V Y  T  GEY   I  +  DIP SPF
Sbjct:  526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631          

HSP 10 Score: 52.7582 bits (125), Expect = 5.333e-6
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PF V V          +YGPGL   + +    F ++T G+ +  +  ++EGPS+ K+ C +  +GS  + Y A  PG Y ++I   +++I  SP+ +++ ++  VD   KVKV G
Sbjct: 1107 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1224          
BLAST of Filamin A vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337100)

HSP 1 Score: 153.68 bits (387), Expect = 1.156e-36
Identity = 143/581 (24.61%), Postives = 252/581 (43.37%), Query Frame = 3
Query:   63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL--GENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLYGSVADCPGVFILDTNGSDQQIGFS---MEGPSKTKIECA----NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            E +R  +E  +  KI++  FTRW N  LK  ++ I +L+ DL +G  L+ LIE+LSQK++ K       R  ++  ++  L FL+ EG+++ NI+  DI+D  +K I  L+W LI HYSI   +  GE++    G      +  LNW+++K+    I+N ++ W +G A+G +V+ C   LC D   W+  +A+ NA  AM  A     + QL+KP E+++ +  ++++MTY+SQ+        + L  + N N+    G  +  +    G      A  + +  S                G VD+ I+ P                 NG + K     N  K+   + S IP   GS  + +K +    +I   PF V V       + V   GPG+  +          D    D   G     +  P+  K   A     + N +    Y   L G++ +++      I +SP+    VK   + + +KV+  G   + T   + D  +         E  P+V      G+ + N++ ++++   +          R ++ V +   +V   P+ +
Sbjct:    2 EAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPI----GPVVGAPANFTVETFS-------------AGKGSVDVDIQGP-----------------NGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFS--GRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFP---VKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGM-NQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEV 542          

HSP 2 Score: 112.849 bits (281), Expect = 3.143e-24
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            G  L +G V    +F V T     G+LAI +EGPSKA+I F D+K G   VSY+VT PGEY   + FN   IP SPF++ V+ D      HK        EV+   +GN  +  P    +  + +  E   L+  +  P G             ++ D FI V    +  Y++ FY    +    +  VK   +H  +  +     V   + +P  V+       A G+GL +     K  F I   N          +L V+IDGPSKV + C E   GY   Y P++ G ++I + Y+N  HI GSPFK+    D  +D   QE
Sbjct: 2000 GSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDA--HK-------LEVQQFPQGNIQADAPYQFMVRKNGAKGE---LDAKIVAPSG-------------TDDDCFIQVIDGEM--YSVRFYP--RENGIHAIHVKFNGVH--IPDSPFRIKVGKDVADPAAVH-------ASGNGLDEVKTGHKADFIINTCNAGVG------TLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNM-HIVGSPFKVNATGDKLADEGAQE 2280          

HSP 3 Score: 90.1225 bits (222), Expect = 2.339e-17
Identity = 84/325 (25.85%), Postives = 143/325 (44.00%), Query Frame = 3
Query:  972 KNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY-SIVIVKSNKVDEIKKVKVIGLENKNT-----KSFIIDSRNSTFEMPPDVECFDKLGVS-----SNNILVTE-------------LEKKYFRIECPLNNAERLIVFVGYFMVQVEGF---------PYA-----IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIEL 1832
            +N++   VD  GN Y+C    ++  + E  + ++   +G             E+   PF V V  P K+ +IV+YGPGL   V   P  F+++TNG    +GF++ GPS+ +IEC + G+GS L+ Y     G Y + I+ + E+I  SP+ + ++ +++   E+ K    GLE          SF +D   +    P DV   D  G        NN   T+             +E  Y  +  P N+  R+ V V     +V+ F         P A     +D  ++ + + KV      + ++  C  I N+D   ++E+
Sbjct:  500 QNVMQSKVD--GNTYEC----HYYPTKEGRYVIMVTFAG------------QEVAKSPFEVKVG-PKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAG-NAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTP-NSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEV 803          

HSP 4 Score: 80.1073 bits (196), Expect = 2.290e-14
Identity = 80/331 (24.17%), Postives = 124/331 (37.46%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTE-PHG--GSSFHP---------IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G       F + T G   G L + +EGPSKA+I++ D K G   V Y  T PGEY  ++ F    I  SP+   +  +  +R     +    CSEV M        ++ +  +    + +P  L   CF+   P G  G SF P         +K++ K  N   F                     ++G + KVK+                                    G GL++   +  N F +   N           L V+I+GPSK +I C +  +G +   Y P   G Y + + +++  H+ GSPF + V
Sbjct: 1620 VTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---NQISVGSCSEVTMPGDITDDDLRALNAS----IQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCER--------------EVGDAKKVKVS-----------------------------------GTGLKEGQTHADNIFSVDTRNAGFG------GLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADH-HVEGSPFTVKV 1887          

HSP 5 Score: 74.3294 bits (181), Expect = 1.559e-12
Identity = 86/327 (26.30%), Postives = 138/327 (42.20%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +V V G  L +G  + +N F V T     G L++ IEGPSKAEI   DK  G   +SY+ T PG Y+  + F    +  SPF + VA + + R   K           +Q + ++  I  +G    L F +      +L   VT P   +    I+++     +DG   ++     +GV+ +            S +    +I GS    T         + PL  +     + A G GL++  V     F +  W           SL ++++GPSK  I   +  +G     Y     G Y +G+ ++++ HIP SPFK+ V  D
Sbjct: 1802 KVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREK-----------IQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEV-----EDGLYAVHFVPKELGVHTV------------SVRYSEMHIPGSPFQFT---------VGPL-RDSGSHLVKAGGSGLERGVVGEAAEFNV--WTREAG----GGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDR-HIPDSPFKVYVSPD 2083          

HSP 6 Score: 71.2478 bits (173), Expect = 1.265e-11
Identity = 39/93 (41.94%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P      G  L KG  N  NKF V T G   G L++ IEGPS+A+++  D + G   V Y  T PGEY   I F    IP SPFR+ V + V+
Sbjct: 1124 PARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD 1216          

HSP 7 Score: 65.0846 bits (157), Expect = 1.001e-9
Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIID-SRNSTFEMPPDVEC--FDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAID 1718
            I  +PFR+     +    + ++GPGL   +   P  F++DT G+ Q  +G ++EGP +  I C + G+G+  + Y     G Y ++I  NE +I  SP+  +IV    V  +K  +V  IG++           F++D S+  +      + C  FD +G    + +V       FRI      A R  + + Y  + V G P+ ++
Sbjct:  914 ITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIV---PVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVN 1117          

HSP 8 Score: 56.9954 bits (136), Expect = 2.588e-7
Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNG-SDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            N+  E    +G V K     N  +   +S    P   GS ++ +K N     +   PF+  V+       + +YGPGL   V   P  F + T G S   +  ++EGPSK  I   +  +G+V + Y    PG YQ+S+   +++I  SPY
Sbjct: 1555 NVTAEVRMPSGKVDKPVIQDN--RDGTVSVKYDPREEGSHELVVKYN--GEPVQGSPFKFHVDSITSG-YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPY 1700          

HSP 9 Score: 55.4546 bits (132), Expect = 7.982e-7
Identity = 37/107 (34.58%), Postives = 50/107 (46.73%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            I V     ++++ P+EV V           G  L  G + +   FVV T+G+  G L   + GPS+AEI   D   G  +V Y  T  GEY   I  +  DIP SPF
Sbjct:  526 IMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGET-GALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF 631          

HSP 10 Score: 52.7582 bits (125), Expect = 5.333e-6
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PF V V          +YGPGL   + +    F ++T G+ +  +  ++EGPS+ K+ C +  +GS  + Y A  PG Y ++I   +++I  SP+ +++ ++  VD   KVKV G
Sbjct: 1107 IPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEET--VDP-SKVKVYG 1224          
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flnb (filamin B, beta (actin binding protein 278) [Source:ZFIN;Acc:ZDB-GENE-041026-1])

HSP 1 Score: 194.126 bits (492), Expect = 6.474e-49
Identity = 152/559 (27.19%), Postives = 247/559 (44.19%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNF-DEIGK-----SFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRN------STFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI 1715
            KI+K  FTRW N  L+  N  I DL+ DL +G +L+ L+E+LS K++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI T + E+   D + K       L W+ +K+    I N S  W  G A+G +V+     LC D   W+S + ++N + AM+ A     +PQL+ P EI+D +  ++++MTY+S F     +              +    G    +    I  + ++++ +       D  + G                 NL V   D +G+    T+   F       F   P   G   + I        I   PF+V V        I  +GPGL G     P  F++++ G+D   +GF++EGPS+ KI C +  +GS  + +     G Y + +M ++E I DSP+   I   +K     KVKV G     T         FI+D+R       + F    D EC D        + ++  +   F      ++  +  + V +  V V G P+ +
Sbjct:   23 KIQKNTFTRWCNEHLRSVNMRISDLKTDLSDGLVLISLLEVLSHKRMFRKYHTRPTFRQLKLDNVSVALEFLDHEKVKLVSIDSKAIVDGNLKLILGLVWTLIQHYSISTPVWEDEANDSVSKLTPEMRLLGWIQNKVPELPITNFSQDWQDGKALGALVDGLAPGLCPDWESWDSVHRVSNTKEAMQQADDWLGVPQLIAPEEILDPAVDEQSVMTYLSLFPKARLKPGAPLKPKKVPKPKACRATG--RGLQSKGIRVEQLAEFKV-------DTCRAG---------------PGNLDVHIRDPSGSEVSVTQKELF--KGVFGFQYTPSAEGDHTVDI--TWVGQHISKSPFKVNVGPEAGPQKIRVWGPGLEGGTVGSPAQFMVESVGADSGMLGFAIEGPSQAKIACDDHNDGSCQVRFWPTEAGEYAVHVMCDDEEIQDSPFMASIRPKSKGFHPDKVKVEGPGVSQTGCVINLQNEFIVDTRQAGEGELAVFAQRADGECVD--------VTISSEQSGVFVCSYTPSSLSKHTIAVTWGGVMVPGSPFIV 545          

HSP 2 Score: 78.1814 bits (191), Expect = 1.183e-13
Identity = 92/334 (27.54%), Postives = 138/334 (41.32%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTS---------NKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +V+  G  L +G V    +F++ TS    G L + ++GPS+  +  +D + G   V Y  T  G Y   + F+   IP SPF   +         H  V P   S+V + N      I          V  P I+N++C       GS    ++ +S +          N+DG   V     T GVY +      G K+ P  KV +E              V +     ++V E   +   + A G GLQ+  +   N F +   N    +      L VT++GPS  Q++C +   G Y   Y P V G Y I IT S +  IPGSPF ++V
Sbjct:  602 KVNAHGPGLTEGVVGEQAEFIIDTSRAGSGRLDVRVDGPSEVTLQCLDDQDGTCTVLYLPTEHGMYQINVLFDNSHIPGSPFGANI---------HHPVDP---SKVLVTNSALQHGI----------VGEPCIVNIDCAKV----GSEDLSVQAISDSGVVVETEVKENEDGTYTVVYVPRTGGVYTLLLK--YGGKVLPVHKVMVEQ-------KVYKSHVKVSRRGGVVVGERETDASQVVASGLGLQKGLIGHPNMFCV---NTRSPV----DDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISIT-SGENSIPGSPFVVSV 892          

HSP 3 Score: 63.1586 bits (152), Expect = 3.960e-9
Identity = 82/344 (23.84%), Postives = 135/344 (39.24%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMD-KKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQ 5903
            + E GD S+    V   G  L  G     ++FVV T     G L + IEGPSK ++   + +  G   +SY    PG Y  +I F+   IP SPF   V D    R             +    K   T+      +L F +   +   ++  V EP G  SF     +  T      ++  A  +GVYN+   N            K + I G     T         + PL      + +  +G  LQ A       F I  W+          +L V+++GP ++++   E ++G  I  Y     G Y + + + ++ H+  SPF ++V+   ++ ++ Q
Sbjct: 1813 QAEIGDASK----VKAFGPGLHTGHTFCKSEFVVDTWDAGYGGLTVVIEGPSKVDVHTKELENDGTCNISYCPIKPGSYKISIKFSDEHIPGSPFTAVVKDQGLMR-----------ENITYNQKAAPTASIGSECSLAFKLQDVDPGTMSAHVYEPSG--SFGEAVILPSTGRDIYVVSFLAKEMGVYNVSIQN------------KGQTISGCPLQYT---------VGPLGRGG-SEKVQVWGQSLQTALATVPADFNI--WSREAGA----GALSVSVEGPGEIELLFDEQMDGSCIVTYTAQQPGDYEVSVMF-DEDHVSQSPFLVSVIAATDTAVSDQ 2110          

HSP 4 Score: 63.1586 bits (152), Expect = 4.307e-9
Identity = 40/125 (32.00%), Postives = 60/125 (48.00%), Query Frame = 3
Query: 4851 ILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDIC 5225
            + R   + V     D SQ    V   G  L KG +   N F V+T   +  +L + +EGPS  +++  D   G+Y V Y  T+PGEY  +I+  +  IP SPF ++V D  N       ++  IC
Sbjct:  791 VSRRGGVVVGERETDASQ----VVASGLGLQKGLIGHPNMFCVNTRSPV-DDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISITSGENSIPGSPFVVSVDDVSNTAGSGDCLQAGIC 910          

HSP 5 Score: 60.8474 bits (146), Expect = 2.334e-8
Identity = 36/121 (29.75%), Postives = 55/121 (45.45%), Query Frame = 3
Query: 4860 LDSISVKTESGDLSQIPYEVHV----------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            L  I +K+   D+ ++P + +            G+ L  G  N    F +         L I IEGPS+A++  +D + G   VSY  T PG+Y   +  N V IP SPF+  + D   R+
Sbjct: 1612 LHQILIKSAENDIPELPLQYYANSLANRSPVAYGRGLVCGIANETATFTICQEDSASSELDITIEGPSEADVHCLDNEDGTCSVSYLPTEPGDYEIQVQHNDVPIPGSPFKAKITDGHMRK 1732          

HSP 6 Score: 56.6102 bits (135), Expect = 4.937e-7
Identity = 52/195 (26.67%), Postives = 92/195 (47.18%), Query Frame = 3
Query:  867 ISDYHIRQLDKPPDVIKDGR-VDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGN-GSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            I+D H+R+ +     +K G  VD  + I   E+DI++ L    +   GN   C         + L  S IP  +G   + I K+     + N P  + ++         + ++GPGL+     C   F++DT +     +   +EGPSK  +    + N G+  I+Y  + PG Y++SI  ++E+I  SP++ V+
Sbjct: 1725 ITDGHMRKSE-----VKLGSAVDFTLDI--TEEDISQ-LSASIMSPTGNDVPCLLK--TQADSHLGISFIPREAGEHLVSIMKD--GEHVSNSPISLSISQAEIGDASKVKAFGPGLHTGHTFCKSEFVVDTWDAGYGGLTVVIEGPSKVDVHTKELENDGTCNISYCPIKPGSYKISIKFSDEHIPGSPFTAVV 1907          

HSP 7 Score: 52.7582 bits (125), Expect = 5.844e-6
Identity = 25/84 (29.76%), Postives = 46/84 (54.76%), Query Frame = 3
Query: 1185 IVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +V+ G GL   +   P +F ++T      +G ++EGPS  ++ C + G G   + Y+  +PG Y++SI   E +I  SP+ + +
Sbjct:  809 VVASGLGLQKGLIGHPNMFCVNTRSPVDDLGVTVEGPSDCQVTCKDGGQGVYGVEYTPTVPGEYKISITSGENSIPGSPFVVSV 892          
BLAST of Filamin A vs. Ensembl Zebrafish
Match: CR352234.3 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529])

HSP 1 Score: 163.696 bits (413), Expect = 1.398e-39
Identity = 137/488 (28.07%), Postives = 225/488 (46.11%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430
            +K  +M  T+ ++ +     KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL +E ++L +I+   I+DG++K I  L+W LI HYSI   + +   +          +  L W+ +KL    I N S  W SG A+G +V++C   LC D   W+ +  ++NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN  M  A  + + IS                G V + ++ P   ++ AK                    N  K+   S   +P ++G   + +        I   PF V V +     + + + GPGL   G++A+    F + T G+   ++   +  PS  K  +EC+  + GN S   TY     G + + I      I  SPY++
Sbjct:   24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 474          

HSP 2 Score: 101.679 bits (252), Expect = 1.066e-20
Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903
            ++V   G  L +       +F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + VA   D  RR+        + S  E   K N  +   V  N     +   V SP      C VTE                 ++D + +       G+Y ID   F G  I G  +K+++                  Q  +P +V+       AYG GL+  T      F +   N S +      +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPF  KIT  R  NS   H+
Sbjct: 2138 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2428          

HSP 3 Score: 76.2554 bits (186), Expect = 5.533e-13
Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN    F V+T     G L++ IEGPSKA+IS  D + G   VSY   +PG+Y   + +N  +IP SPF   +  D + R+ H  V             G++  I          +   ++  L   +T P G      +K +     ++G + +             +F+  +IG    V I+     + S+ +S      +IN   + +    +   G GL +A       F I      ++       L ++I+GPSKV I+  +  +G     Y P   G Y I I ++++ H+PGS F + V
Sbjct: 1767 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2033          

HSP 4 Score: 74.3294 bits (181), Expect = 1.795e-12
Identity = 84/314 (26.75%), Postives = 141/314 (44.90%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C     + ++  ++ + G + + Y    PG+YV  + F    IP+SPF++TV    +   L  H+         + N G + +   +G N +  V+     +L    T   G   G    P  K++K   T NKDG + V +A T  G++ +D              +K + IH  +  + L   VD        VN    ++ AYG GL    VN+     +F  N  ++    E  L + I+GPSK  ISC ++ +G     Y+P++ G Y I + Y++K +IPGSPF   +  D +  ++H
Sbjct: 1589 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTV-HTCHAHHLFIHIS-------FISNSGQTLTNGQLGMNGL-DVAGLRPFDLVIPFTIQKGEITGDVRMPSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1861          

HSP 5 Score: 65.855 bits (159), Expect = 6.442e-10
Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +       +F++ T     G L++ IEGPSK +I+  D++ G   V+Y  T PG Y+  I F    +P S F + V  +         +K  I        K  + S+  VG      +  PE  I ++   VT P G    H  + M +  N    I    + +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++++ HIP SPF + V   P+ D
Sbjct: 1940 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2230          

HSP 6 Score: 64.6994 bits (156), Expect = 1.361e-9
Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484
            SF   P   G++ I I        I   PF V +        + ++GPGL   V      F+++  G D   +GFS+EGPS  KIEC + G+GS  + Y    PG Y + ++   E+I  SP+   I+ +   D    KVK  G
Sbjct:  542 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 683          

HSP 7 Score: 61.6178 bits (148), Expect = 1.305e-8
Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   ++    P  +G  ++ IK +   + I   P +  V+  N    + +YGPGL   + + P VF ++T +  +  +  ++EGPSK  I C +  +G+  ++Y  +LPG Y + +  N++NI  SP+
Sbjct: 1723 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1847          

HSP 8 Score: 56.6102 bits (135), Expect = 4.231e-7
Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3
Query:  924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + DL +KIP I   IA ++  +    +G V+K        ++N      +P   G   + +K       +   PF+  V    +     + + GPGL  + A  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N+E+I DSP+  V+  ++  D+ +++ V  L+    K
Sbjct: 2058 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2245          

HSP 9 Score: 53.1434 bits (126), Expect = 5.580e-6
Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3
Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180
            KPT   Q+I     I +    G +S+ PY V+V      +LC         KG  V    +F V+T G   G+L + I+GP   E     K +G  +Y   Y  + PG Y+  I++    IP SPF + +  +
Sbjct:  449 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 576          

HSP 10 Score: 53.1434 bits (126), Expect = 5.580e-6
Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493
            S  +   PFRV V        +  +GPGL   + + P  F ++T G+        MEGPS+ K+ C +  +GS  + Y    PG Y L++    + I  SP+S+ +   + VD  K K +  GL N
Sbjct: 1248 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1371          
BLAST of Filamin A vs. Ensembl Zebrafish
Match: CR352234.2 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529])

HSP 1 Score: 163.696 bits (413), Expect = 1.398e-39
Identity = 137/488 (28.07%), Postives = 225/488 (46.11%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430
            +K  +M  T+ ++ +     KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL +E ++L +I+   I+DG++K I  L+W LI HYSI   + +   +          +  L W+ +KL    I N S  W SG A+G +V++C   LC D   W+ +  ++NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN  M  A  + + IS                G V + ++ P   ++ AK                    N  K+   S   +P ++G   + +        I   PF V V +     + + + GPGL   G++A+    F + T G+   ++   +  PS  K  +EC+  + GN S   TY     G + + I      I  SPY++
Sbjct:   24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 474          

HSP 2 Score: 101.679 bits (252), Expect = 1.066e-20
Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903
            ++V   G  L +       +F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + VA   D  RR+        + S  E   K N  +   V  N     +   V SP      C VTE                 ++D + +       G+Y ID   F G  I G  +K+++                  Q  +P +V+       AYG GL+  T      F +   N S +      +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPF  KIT  R  NS   H+
Sbjct: 2138 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2428          

HSP 3 Score: 76.2554 bits (186), Expect = 5.533e-13
Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN    F V+T     G L++ IEGPSKA+IS  D + G   VSY   +PG+Y   + +N  +IP SPF   +  D + R+ H  V             G++  I          +   ++  L   +T P G      +K +     ++G + +             +F+  +IG    V I+     + S+ +S      +IN   + +    +   G GL +A       F I      ++       L ++I+GPSKV I+  +  +G     Y P   G Y I I ++++ H+PGS F + V
Sbjct: 1767 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2033          

HSP 4 Score: 74.3294 bits (181), Expect = 1.795e-12
Identity = 84/314 (26.75%), Postives = 141/314 (44.90%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C     + ++  ++ + G + + Y    PG+YV  + F    IP+SPF++TV    +   L  H+         + N G + +   +G N +  V+     +L    T   G   G    P  K++K   T NKDG + V +A T  G++ +D              +K + IH  +  + L   VD        VN    ++ AYG GL    VN+     +F  N  ++    E  L + I+GPSK  ISC ++ +G     Y+P++ G Y I + Y++K +IPGSPF   +  D +  ++H
Sbjct: 1589 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTV-HTCHAHHLFIHIS-------FISNSGQTLTNGQLGMNGL-DVAGLRPFDLVIPFTIQKGEITGDVRMPSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1861          

HSP 5 Score: 65.855 bits (159), Expect = 6.442e-10
Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +       +F++ T     G L++ IEGPSK +I+  D++ G   V+Y  T PG Y+  I F    +P S F + V  +         +K  I        K  + S+  VG      +  PE  I ++   VT P G    H  + M +  N    I    + +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++++ HIP SPF + V   P+ D
Sbjct: 1940 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2230          

HSP 6 Score: 64.6994 bits (156), Expect = 1.361e-9
Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484
            SF   P   G++ I I        I   PF V +        + ++GPGL   V      F+++  G D   +GFS+EGPS  KIEC + G+GS  + Y    PG Y + ++   E+I  SP+   I+ +   D    KVK  G
Sbjct:  542 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 683          

HSP 7 Score: 61.6178 bits (148), Expect = 1.305e-8
Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   ++    P  +G  ++ IK +   + I   P +  V+  N    + +YGPGL   + + P VF ++T +  +  +  ++EGPSK  I C +  +G+  ++Y  +LPG Y + +  N++NI  SP+
Sbjct: 1723 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1847          

HSP 8 Score: 56.6102 bits (135), Expect = 4.231e-7
Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3
Query:  924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + DL +KIP I   IA ++  +    +G V+K        ++N      +P   G   + +K       +   PF+  V    +     + + GPGL  + A  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N+E+I DSP+  V+  ++  D+ +++ V  L+    K
Sbjct: 2058 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2245          

HSP 9 Score: 53.1434 bits (126), Expect = 5.580e-6
Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3
Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180
            KPT   Q+I     I +    G +S+ PY V+V      +LC         KG  V    +F V+T G   G+L + I+GP   E     K +G  +Y   Y  + PG Y+  I++    IP SPF + +  +
Sbjct:  449 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 576          

HSP 10 Score: 53.1434 bits (126), Expect = 5.580e-6
Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493
            S  +   PFRV V        +  +GPGL   + + P  F ++T G+        MEGPS+ K+ C +  +GS  + Y    PG Y L++    + I  SP+S+ +   + VD  K K +  GL N
Sbjct: 1248 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1371          
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145])

HSP 1 Score: 162.54 bits (410), Expect = 3.038e-39
Identity = 138/489 (28.22%), Postives = 226/489 (46.22%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSI 1430
            +K  +M  T+ ++ +     KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL +E ++L +I+   I+DG++K I  L+W LI HYSI   + +   +          +  L W+ +KL    I N S  W SG A+G +V++C   LC D   W+ +  ++NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF        + L  + N  K    G    + I+  GN  M  A  + + IS                G V + ++ P   ++ AK                    N  K+   S   +P ++G   + +        I   PF V V +     + + + GPGL   G++A+    F + T G+   ++   +  PS  K  +EC+  + GN S   TY     G + + I      I  SPY++
Sbjct:   24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYG---PAGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYVPKVTGQHKVTVLFA--GQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTV 475          

HSP 2 Score: 101.679 bits (252), Expect = 9.090e-21
Identity = 109/342 (31.87%), Postives = 145/342 (42.40%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPF--KITVLRDPNSDLNHQ 5903
            ++V   G  L +       +F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + VA   D  RR+        + S  E   K N  +   V  N     +   V SP      C VTE                 ++D + +       G+Y ID   F G  I G  +K+++                  Q  +P +V+       AYG GL+  T      F +   N S +      +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPF  KIT  R  NS   H+
Sbjct: 2146 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGETG--------------QAGDPGMVS-------AYGAGLEGGTTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHE 2436          

HSP 3 Score: 76.2554 bits (186), Expect = 4.963e-13
Identity = 82/319 (25.71%), Postives = 133/319 (41.69%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN    F V+T     G L++ IEGPSKA+IS  D + G   VSY   +PG+Y   + +N  +IP SPF   +  D + R+ H  V             G++  I          +   ++  L   +T P G      +K +     ++G + +             +F+  +IG    V I+     + S+ +S      +IN   + +    +   G GL +A       F I      ++       L ++I+GPSKV I+  +  +G     Y P   G Y I I ++++ H+PGS F + V
Sbjct: 1775 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTATLTTPSGREEPCLLKML-----RNGHVGI-------------SFVPKEIGEHL-VNIKKNGRHIPSSPISV-----MINQSEIGDA-SRVRVTGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 2041          

HSP 4 Score: 72.0182 bits (175), Expect = 8.360e-12
Identity = 80/320 (25.00%), Postives = 137/320 (42.81%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVAD-DVNRRILHKHVKPDICSEVEM-----------QNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C     + ++  ++ + G + + Y    PG+YV  + F    IP+SPF++T  + D   +++ +           M            N  +   ++P    + F +   EI      V  P G      + K   T NKDG + V +A T  G++ +D              +K + IH  +  + L   VD        VN    ++ AYG GL    VN+     +F  N  ++    E  L + I+GPSK  ISC ++ +G     Y+P++ G Y I + Y++K +IPGSPF   +  D +  ++H
Sbjct: 1590 AGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTALEGDSPDQLMQQSQNLQYAYAPNMGQTWATDGQLGMNGLDVAGLRPFDLVIPFTIQKGEITG---DVRMPSG-----KVAKPDITDNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVDY-------VNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDK-NIPGSPFMSKITGDDSMRMSH 1869          

HSP 5 Score: 66.2402 bits (160), Expect = 5.925e-10
Identity = 88/341 (25.81%), Postives = 143/341 (41.94%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +       +F++ T     G L++ IEGPSK +I+  D++ G   V+Y  T PG Y+  I F    +P S F + V  +         +K  I        K  + S+  VG      +  PE  I ++   VT P G    H  + M +  N    I    + +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++++ HIP SPF + V   P+ D
Sbjct: 1948 QSEIGDASR----VRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-HIPDSPFVVPV-ASPSDD 2238          

HSP 6 Score: 65.0846 bits (157), Expect = 1.316e-9
Identity = 46/144 (31.94%), Postives = 67/144 (46.53%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVD-EIKKVKVIG 1484
            SF   P   G++ I I        I   PF V +        + ++GPGL   V      F+++  G D   +GFS+EGPS  KIEC + G+GS  + Y    PG Y + ++   E+I  SP+   I+ +   D    KVK  G
Sbjct:  543 SFDYYPSTPGNYIITITWG--GQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYG 684          

HSP 7 Score: 61.6178 bits (148), Expect = 1.339e-8
Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   ++    P  +G  ++ IK +   + I   P +  V+  N    + +YGPGL   + + P VF ++T +  +  +  ++EGPSK  I C +  +G+  ++Y  +LPG Y + +  N++NI  SP+
Sbjct: 1731 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPF 1855          

HSP 8 Score: 56.6102 bits (135), Expect = 4.681e-7
Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 3
Query:  924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + DL +KIP I   IA ++  +    +G V+K        ++N      +P   G   + +K       +   PF+  V    +     + + GPGL  + A  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N+E+I DSP+  V+  ++  D+ +++ V  L+    K
Sbjct: 2066 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2253          

HSP 9 Score: 53.1434 bits (126), Expect = 5.352e-6
Identity = 40/133 (30.08%), Postives = 60/133 (45.11%), Query Frame = 3
Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180
            KPT   Q+I     I +    G +S+ PY V+V      +LC         KG  V    +F V+T G   G+L + I+GP   E     K +G  +Y   Y  + PG Y+  I++    IP SPF + +  +
Sbjct:  450 KPTQEGQHI-----IYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSE 577          

HSP 10 Score: 53.1434 bits (126), Expect = 5.443e-6
Identity = 39/126 (30.95%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1122 SMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK-KVKVIGLEN 1493
            S  +   PFRV V        +  +GPGL   + + P  F ++T G+        MEGPS+ K+ C +  +GS  + Y    PG Y L++    + I  SP+S+ +   + VD  K K +  GL N
Sbjct: 1249 SSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPV--HDTVDPTKVKCQGQGLGN 1372          
BLAST of Filamin A vs. Ensembl Zebrafish
Match: flncb (filamin C, gamma b (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-041008-175])

HSP 1 Score: 162.155 bits (409), Expect = 4.176e-39
Identity = 134/498 (26.91%), Postives = 222/498 (44.58%), Query Frame = 3
Query:   60 QEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNL----PNKKPTIVSYGPGL--YGSVADCP---------------GVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            +EM  T+ ++ +     KI++  FTRW N  LK  N+ I DLQ DL +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  +        L W+ +K+    I+N    W  G A+G +V+ C   LC D   W+ S  + NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF     +     R    +    K     I+  GN  +  A                   + ++ G  ++L+ I   E    +  V+   D+N                  S   +P + G     +K      +I   PF V V+     PNK   + + GPGL   G+VA+ P               GV I+D+ G    +   +E          N G+     TY  +L G + + +    + I  SP+++ I ++
Sbjct:   28 EEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCLNRKILDLQKDLTDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKLTPKQRLLGWIQNKVPQLHINNFHRDWRDGKALGALVDNCAPGLCPDWETWDPSQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKTLHPKRAKAYGPGIEPRGNVVLKPAEFVV---------------ETVEAGLGEVLVYIEDPEGHTEEARVIPNNDRN---------------RSYSVVYVPKVEGLHK--VKVLFAGQDIDRSPFLVNVSKALGDPNK---VQARGPGLEPVGNVANKPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILE----------NKGDSVFRCTYGPILEGPHTIYVTFAGQQIPRSPFTVHISEA 480          

HSP 2 Score: 107.071 bits (266), Expect = 2.405e-22
Identity = 103/329 (31.31%), Postives = 143/329 (43.47%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA---DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   V+Y V  PG+Y  +I FN   IP SPF + +A   DD   R+L       + S  EM  K N  +   V  N     +   V +P      C++TE       H I+ + + +             GV++ID   F G  I G  +K+++                  Q  +P +V        A+G GL+  T    + F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2364 HKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYIVQEPGDYEVSIKFNDEHIPDSPFIVPIASLSDDA--RLL------TVTSLQEMGLKVNQEASFAVQLNGARGAIDAKVHTPSGAVEECYITELDNDK--HAIRFIPREN-------------GVHSIDV-RFNGSHIPGSPFKIRVGEPG--------------QAGDPGMVT-------AFGPGLEGGTTGVPSDFIVNTCNAGSG------ALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV 2641          

HSP 3 Score: 69.707 bits (169), Expect = 4.851e-11
Identity = 50/162 (30.86%), Postives = 83/162 (51.23%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY--SIVIVKSNKVDEIKKVKVIGLE------NKNTKSFIIDSRNS 1532
            PI  G + I +    ++  I   PF V ++       + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+   S+   E  K    GLE      NK  + F ID+R +
Sbjct:  589 PIFCGKYIITVTWGGHA--IPRSPFEVIISEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAASDVFPEKVKCYGPGLEPTGCIVNKPAE-FTIDARGA 747          

HSP 4 Score: 63.5438 bits (153), Expect = 3.862e-9
Identity = 36/92 (39.13%), Postives = 47/92 (51.09%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V+  G  L  G VN +  F + T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y   + F+   I  SPF   +  D + R
Sbjct: 1910 VNAYGPGLSHGMVNKSATFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIAGSPFTAKITGDDSMR 2001          

HSP 5 Score: 63.1586 bits (152), Expect = 4.236e-9
Identity = 40/132 (30.30%), Postives = 66/132 (50.00%), Query Frame = 3
Query: 1047 SNEL-SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            SNE+ +   IP   G + + I  +     +   PF V   +P     + +YGPGL G +   P  F +DT G+        +EGP + KIEC + G+GS  ++Y    PG Y ++I+  + +I  SP+  ++
Sbjct: 1070 SNEVHTVKYIPPEEGPYKVDISYD--GNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFADAHIPGSPFKAMV 1199          

HSP 6 Score: 63.1586 bits (152), Expect = 5.096e-9
Identity = 81/338 (23.96%), Postives = 134/338 (39.64%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTS--GKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKP-DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV--LRDPN 5885
            P +V   G  L +G VN    F V  S  G+    + I  +  ++AE+   +   G Y ++Y     G Y   I +    +P  P R+ V    D    ++    V+P  +  EV      ++     +G N I   + +P   N + +VT+   G+      ++  T+ +DG   I V    + V    F   + +   PS                                     + AYG GL++  VN+ N F +      E+       L + I+GPS+ ++SC ++ +G     YIP   G Y + IT+     IPGSPF++ V  L DP+
Sbjct: 1205 PSKVTASGPGLERGKVNEAGSFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITIKYGGHAVPKFPARVQVDPALDTSGIKVYGPGVEPRGVLREVTTHFIVDTRVHNKMGGNHIKVRIVNPSGANTDAYVTDKADGTY-----RVEYTAYEDGVHLIEVLYDDVPVPKSPFRVAVAEGCDPS------------------------------------RVRAYGPGLEEGLVNKPNRFTV------ETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGEYDVNITFGG-LPIPGSPFRVPVRELVDPS 1494          

HSP 7 Score: 58.151 bits (139), Expect = 1.569e-7
Identity = 41/119 (34.45%), Postives = 57/119 (47.90%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228
            ++E GD S+    V V GK L +G      +F+V T     G L + IEGPSK +I+  D   G   V+Y  T PG Y+  I F    +P SPF + V  +  +   I  K   P I +
Sbjct: 2083 QSEIGDASK----VKVSGKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRMKESITRKRQAPSIAT 2197          

HSP 8 Score: 56.9954 bits (136), Expect = 3.486e-7
Identity = 39/130 (30.00%), Postives = 66/130 (50.77%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            ++ +   IP  +G   I ++ N     I   PF++ V  P +   P +V ++GPGL G     P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI     ++I  SP+
Sbjct: 2511 DKHAIRFIPRENGVHSIDVRFN--GSHIPGSPFKIRVGEPGQAGDPGMVTAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEG-YKVTYTPMAPGSYLISIKYGGPQHIVGSPF 2637          

HSP 9 Score: 54.6842 bits (130), Expect = 1.608e-6
Identity = 38/140 (27.14%), Postives = 69/140 (49.29%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVN---LPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             +  S  P   G   + +KKN     + N PF++ V    + +     VS G GL          FI+DT  +    +G S+EGPSK  I C+++ +G+  +TY    PG Y ++I   ++++  SP+++ ++   ++ E
Sbjct: 2048 HIGISFTPKEVGEHVVSVKKN--GKHVTNSPFKIMVGQSEIGDASKVKVS-GKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRMKE 2184          
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165])

HSP 1 Score: 164.081 bits (414), Expect = 1.415e-39
Identity = 138/512 (26.95%), Postives = 230/512 (44.92%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNSTFEMP 1547
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++     ++  FS    Q ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K+       L W+ +K+    I N S  W  G A+G +V++C   LC D   W+    + NA+ AM+ A     +PQ++ P EIID +  + ++MTY+SQF          L+ + N K     +     ++  GN     A  + + IS                G  ++L+ I                D  GN  +    GN  K+   S   +P ++G   + +        I   PF V V       + + + GPGL   G++A+ P  F + T G+    IG  +  P    +  ++   + GN     TY  +  G + ++I    E    SPY + I ++   +  +     ++  G+  + T  F +D++ +    P
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAAGMVEP 488          

HSP 2 Score: 112.849 bits (281), Expect = 5.112e-24
Identity = 102/317 (32.18%), Postives = 142/317 (44.79%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFK 5861
            G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y   I FN   IP SPF + +   +DD  R  +    +  +       N+  S +I+  G    +   V SP      CFVTE        P K   +   ++          G++ ID   F G  + G  +KV++                  Q  +P +V        AYGDGL+  T  +++ F I   N S++      +L VTI+GPSKV + C E   GY   Y P+  G+Y IG+ Y    HI GSPFK
Sbjct: 2170 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFK 2438          

HSP 3 Score: 82.4185 bits (202), Expect = 9.811e-15
Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3
Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            F   P+  G + + I    +   I   PF V V L      + ++GPGLY  +A     F++++ GS+   +GF++EGPS+ KIEC + G+GS  + Y    PG Y + IM ++E+I +SPY  +I  ++   +  KVK  G
Sbjct:  510 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 649          

HSP 4 Score: 70.0922 bits (170), Expect = 4.613e-11
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   +S   +P  +G  ++ IK N     I   P +  VN PN   ++ +YGPGL   VA+ P  F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+ +I  SP+
Sbjct: 1750 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1874          

HSP 5 Score: 70.0922 bits (170), Expect = 4.691e-11
Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PGNLA+    +  SKAE++  D K G Y V+Y     G Y  A+ +    +P  P R+ V   V+   + K   P I       E       ++ S+   G N   HV +         +T P G S+ + ++      N DG  ++       G + I       D+  P+   K+          T  C  D               + A G GL +A  N+ N F         S+I +      L +T++GPS+ ++SC ++ +G     Y P V G Y + ITY  + HIPGSPF++ V
Sbjct: 1127 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1409          

HSP 6 Score: 68.1662 bits (165), Expect = 2.221e-10
Identity = 83/309 (26.86%), Postives = 120/309 (38.83%), Query Frame = 3
Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKG--NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867
            FVV  +    G +   I GP   + E   ++   G Y + Y     G YV  + F   DIP+SPF + V                  SE +    G  N  S +P    + F + + EI      V  P G ++   I       NKDG +++              ++  + G             L    + C+      +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y N  HI GSPF  KIT
Sbjct: 1630 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMV------------------SETDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1879          

HSP 7 Score: 66.2402 bits (160), Expect = 7.201e-10
Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   I  SPF   + DD  RR
Sbjct: 1794 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1885          

HSP 8 Score: 61.2326 bits (147), Expect = 2.583e-8
Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351
            P  V   G  L +   N  N F V T G   G L I +EGPS++++S  D K G   V Y   + G+Y   I+++   IP SPFR+ V D V+             S+V++   G  T+++  + +      S   I  L   VT P G
Sbjct: 1322 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1458          

HSP 9 Score: 60.8474 bits (146), Expect = 3.645e-8
Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1019 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1117          

HSP 10 Score: 59.3066 bits (142), Expect = 8.517e-8
Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873
            ++E GD S+    V   G  L +G     + F+V T     G L++ +EGPSK +I   D + G   VSY  T PG Y+ +I F    +P SPF   V  +  V   I  +   P + S               VG     ++  PEI    L   V  P G      I  + + ++   F+       G++ +            S K + E++ GS    T         + PL      + + A G GL++        F I  W            L + ++GPSK +IS  +  +G     Y+    G Y + I ++++ HIP SPF + ++
Sbjct: 1966 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2251          

HSP 11 Score: 58.9214 bits (141), Expect = 1.352e-7
Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T DG+ I GSPF + V +  D        P   +     + Q  + ++ K G  P    V+    T+
Sbjct: 1353 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1460          

HSP 12 Score: 54.6842 bits (130), Expect = 2.581e-6
Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
            N +  S IP   G   + IKKN     I N P  + V          + ++GPGL          FI+DT  +    +  ++EGPSK  I+  ++ +G+  ++Y    PG+Y +SI   +E++  SP++  ++   +V E
Sbjct: 1930 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2067          

HSP 13 Score: 52.7582 bits (125), Expect = 9.817e-6
Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532
            + N PF+V V        + + G GL  ++ + P +F + T G+    +G ++EGPS++K+ C +  +GS  + Y+  + G Y ++I  + E+I  SP+ + +     V +  KVK+ G      +  K  + F +D+  +
Sbjct: 1307 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1444          
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165])

HSP 1 Score: 163.696 bits (413), Expect = 1.780e-39
Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++     ++  FS    Q ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K+       L W+ +K+    I N S  W  G A+G +V++C   LC D   W+    + NA+ AM+ A     +PQ++ P EIID +  + ++MTY+SQF          L+ + N K     +     ++  GN     A  + + IS                G  ++L+ I                D  GN  +    GN  K+   S   +P ++G   + +        I   PF V V       + + + GPGL   G++A+ P  F + T G+    IG  +  P    +  ++   + GN     TY  +  G + ++I    E    SPY + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483          

HSP 2 Score: 115.931 bits (289), Expect = 6.229e-25
Identity = 103/320 (32.19%), Postives = 146/320 (45.62%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y   I FN   IP SPF + +   +DD  R  +    +  +       N+  S +I+  G    +   V SP      CFVTE   G+  + ++ M + +             G++ ID   F G  + G  +KV++                  Q  +P +V        AYGDGL+  T  +++ F I   N S++      +L VTI+GPSKV + C E   GY   Y P+  G+Y IG+ Y    HI GSPFK  V
Sbjct: 2231 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTELEPGN--YAVRFMPREN-------------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2502          

HSP 3 Score: 82.4185 bits (202), Expect = 9.288e-15
Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3
Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            F   P+  G + + I    +   I   PF V V L      + ++GPGLY  +A     F++++ GS+   +GF++EGPS+ KIEC + G+GS  + Y    PG Y + IM ++E+I +SPY  +I  ++   +  KVK  G
Sbjct:  514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653          

HSP 4 Score: 73.9442 bits (180), Expect = 3.065e-12
Identity = 84/315 (26.67%), Postives = 127/315 (40.32%), Query Frame = 3
Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKP------DICSEVEMQNKG--NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867
            FVV  +    G +   I GP   + E   ++   G Y + Y     G YV  + F   DIP+SPF +   D+V  ++  + +         + SE +    G  N  S +P    + F + + EI      V  P G ++   I       NKDG +++              ++  + G             L    + C+      +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y N  HI GSPF  KIT
Sbjct: 1667 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMATDEVPVQVQQQSLSACPPGYQPLVSETDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1940          

HSP 5 Score: 70.0922 bits (170), Expect = 4.706e-11
Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PGNLA+    +  SKAE++  D K G Y V+Y     G Y  A+ +    +P  P R+ V   V+   + K   P I       E       ++ S+   G N   HV +         +T P G S+ + ++      N DG  ++       G + I       D+  P+   K+          T  C  D               + A G GL +A  N+ N F         S+I +      L +T++GPS+ ++SC ++ +G     Y P V G Y + ITY  + HIPGSPF++ V
Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416          

HSP 6 Score: 70.0922 bits (170), Expect = 4.826e-11
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   +S   +P  +G  ++ IK N     I   P +  VN PN   ++ +YGPGL   VA+ P  F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+ +I  SP+
Sbjct: 1811 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1935          

HSP 7 Score: 66.2402 bits (160), Expect = 7.223e-10
Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   I  SPF   + DD  RR
Sbjct: 1855 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1946          

HSP 8 Score: 60.8474 bits (146), Expect = 3.625e-8
Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124          

HSP 9 Score: 59.6918 bits (143), Expect = 6.693e-8
Identity = 35/93 (37.63%), Postives = 48/93 (51.61%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L +   N  N F V T G   G L I +EGPS++++S  D K G   V Y   + G+Y   I+++   IP SPFR+ V D V+
Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVD 1421          

HSP 10 Score: 59.3066 bits (142), Expect = 8.540e-8
Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873
            ++E GD S+    V   G  L +G     + F+V T     G L++ +EGPSK +I   D + G   VSY  T PG Y+ +I F    +P SPF   V  +  V   I  +   P + S               VG     ++  PEI    L   V  P G      I  + + ++   F+       G++ +            S K + E++ GS    T         + PL      + + A G GL++        F I  W            L + ++GPSK +IS  +  +G     Y+    G Y + I ++++ HIP SPF + ++
Sbjct: 2027 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2312          

HSP 11 Score: 56.6102 bits (135), Expect = 6.578e-7
Identity = 28/103 (27.18%), Postives = 48/103 (46.60%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSS 2369
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T DG+ I GSPF + V +  D        P   +     + Q  + ++ K G  P    V+ 
Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTG 1462          

HSP 12 Score: 54.6842 bits (130), Expect = 2.460e-6
Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
            N +  S IP   G   + IKKN     I N P  + V          + ++GPGL          FI+DT  +    +  ++EGPSK  I+  ++ +G+  ++Y    PG+Y +SI   +E++  SP++  ++   +V E
Sbjct: 1991 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2128          

HSP 13 Score: 52.7582 bits (125), Expect = 9.435e-6
Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532
            + N PF+V V        + + G GL  ++ + P +F + T G+    +G ++EGPS++K+ C +  +GS  + Y+  + G Y ++I  + E+I  SP+ + +     V +  KVK+ G      +  K  + F +D+  +
Sbjct: 1314 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1451          
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165])

HSP 1 Score: 163.696 bits (413), Expect = 2.192e-39
Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++     ++  FS    Q ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K+       L W+ +K+    I N S  W  G A+G +V++C   LC D   W+    + NA+ AM+ A     +PQ++ P EIID +  + ++MTY+SQF          L+ + N K     +     ++  GN     A  + + IS                G  ++L+ I                D  GN  +    GN  K+   S   +P ++G   + +        I   PF V V       + + + GPGL   G++A+ P  F + T G+    IG  +  P    +  ++   + GN     TY  +  G + ++I    E    SPY + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483          

HSP 2 Score: 113.62 bits (283), Expect = 3.289e-24
Identity = 103/320 (32.19%), Postives = 143/320 (44.69%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y   I FN   IP SPF + +   +DD  R  +    +  +       N+  S +I+  G    +   V SP      CFVTE        P K   +   ++          G++ ID   F G  + G  +KV++                  Q  +P +V        AYGDGL+  T  +++ F I   N S++      +L VTI+GPSKV + C E   GY   Y P+  G+Y IG+ Y    HI GSPFK  V
Sbjct: 2216 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2487          

HSP 3 Score: 82.4185 bits (202), Expect = 9.678e-15
Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3
Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            F   P+  G + + I    +   I   PF V V L      + ++GPGLY  +A     F++++ GS+   +GF++EGPS+ KIEC + G+GS  + Y    PG Y + IM ++E+I +SPY  +I  ++   +  KVK  G
Sbjct:  514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653          

HSP 4 Score: 70.0922 bits (170), Expect = 4.742e-11
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   +S   +P  +G  ++ IK N     I   P +  VN PN   ++ +YGPGL   VA+ P  F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+ +I  SP+
Sbjct: 1765 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1889          

HSP 5 Score: 70.0922 bits (170), Expect = 4.823e-11
Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PGNLA+    +  SKAE++  D K G Y V+Y     G Y  A+ +    +P  P R+ V   V+   + K   P I       E       ++ S+   G N   HV +         +T P G S+ + ++      N DG  ++       G + I       D+  P+   K+          T  C  D               + A G GL +A  N+ N F         S+I +      L +T++GPS+ ++SC ++ +G     Y P V G Y + ITY  + HIPGSPF++ V
Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416          

HSP 6 Score: 66.2402 bits (160), Expect = 7.279e-10
Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   I  SPF   + DD  RR
Sbjct: 1809 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1900          

HSP 7 Score: 63.929 bits (154), Expect = 3.563e-9
Identity = 79/307 (25.73%), Postives = 117/307 (38.11%), Query Frame = 3
Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867
            FVV  +    G +   I GP   + E   ++   G Y + Y     G YV  + F   DIP+SPF +                    ++       N  S +P    + F + + EI      V  P G ++   I       NKDG +++              ++  + G             L    + C+      +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y N  HI GSPF  KIT
Sbjct: 1648 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVM-------------------TDYAQVGSMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1894          

HSP 8 Score: 61.2326 bits (147), Expect = 2.610e-8
Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351
            P  V   G  L +   N  N F V T G   G L I +EGPS++++S  D K G   V Y   + G+Y   I+++   IP SPFR+ V D V+             S+V++   G  T+++  + +      S   I  L   VT P G
Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1465          

HSP 9 Score: 60.8474 bits (146), Expect = 3.592e-8
Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124          

HSP 10 Score: 58.9214 bits (141), Expect = 1.389e-7
Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T DG+ I GSPF + V +  D        P   +     + Q  + ++ K G  P    V+    T+
Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1467          

HSP 11 Score: 56.225 bits (134), Expect = 7.778e-7
Identity = 86/353 (24.36%), Postives = 141/353 (39.94%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-------EVEMQNKGNSTSIKPVGKNLIFH---------VSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873
            ++E GD S+    V   G  L +G     + F+V T     G L++ +EGPSK +I   D + G   VSY  T PG Y+ +I F    +P SPF   V  +  V   I  +   P + S        +++  KG      P+  +   H         +SS +I    L   V  P G      I  + + ++   F+       G++ +            S K + E++ GS    T         + PL      + + A G GL++        F I  W            L + ++GPSK +IS  +  +G     Y+    G Y + I ++++ HIP SPF + ++
Sbjct: 1981 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVASVGGLCELNLKIPGKGVQKVWAPLINSNEGHYFVESQTKQISSAKIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2297          

HSP 12 Score: 54.6842 bits (130), Expect = 2.480e-6
Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
            N +  S IP   G   + IKKN     I N P  + V          + ++GPGL          FI+DT  +    +  ++EGPSK  I+  ++ +G+  ++Y    PG+Y +SI   +E++  SP++  ++   +V E
Sbjct: 1945 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2082          

HSP 13 Score: 52.7582 bits (125), Expect = 8.966e-6
Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532
            + N PF+V V        + + G GL  ++ + P +F + T G+    +G ++EGPS++K+ C +  +GS  + Y+  + G Y ++I  + E+I  SP+ + +     V +  KVK+ G      +  K  + F +D+  +
Sbjct: 1314 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1451          
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165])

HSP 1 Score: 163.696 bits (413), Expect = 2.250e-39
Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++     ++  FS    Q ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K+       L W+ +K+    I N S  W  G A+G +V++C   LC D   W+    + NA+ AM+ A     +PQ++ P EIID +  + ++MTY+SQF          L+ + N K     +     ++  GN     A  + + IS                G  ++L+ I                D  GN  +    GN  K+   S   +P ++G   + +        I   PF V V       + + + GPGL   G++A+ P  F + T G+    IG  +  P    +  ++   + GN     TY  +  G + ++I    E    SPY + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483          

HSP 2 Score: 113.62 bits (283), Expect = 3.112e-24
Identity = 103/320 (32.19%), Postives = 143/320 (44.69%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGK--NLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y   I FN   IP SPF + +   +DD  R  +    +  +       N+  S +I+  G    +   V SP      CFVTE        P K   +   ++          G++ ID   F G  + G  +KV++                  Q  +P +V        AYGDGL+  T  +++ F I   N S++      +L VTI+GPSKV + C E   GY   Y P+  G+Y IG+ Y    HI GSPFK  V
Sbjct: 2165 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQESGL-----KVNQPASFAIRLNGARGKIDAKVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2436          

HSP 3 Score: 82.0333 bits (201), Expect = 1.132e-14
Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3
Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            F   P+  G + + I    +   I   PF V V L      + ++GPGLY  +A     F++++ GS+   +GF++EGPS+ KIEC + G+GS  + Y    PG Y + IM ++E+I +SPY  +I  ++   +  KVK  G
Sbjct:  514 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 653          

HSP 4 Score: 70.0922 bits (170), Expect = 4.691e-11
Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PGNLA+    +  SKAE++  D K G Y V+Y     G Y  A+ +    +P  P R+ V   V+   + K   P I       E       ++ S+   G N   HV +         +T P G S+ + ++      N DG  ++       G + I       D+  P+   K+          T  C  D               + A G GL +A  N+ N F         S+I +      L +T++GPS+ ++SC ++ +G     Y P V G Y + ITY  + HIPGSPF++ V
Sbjct: 1134 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1416          

HSP 5 Score: 70.0922 bits (170), Expect = 5.189e-11
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   +S   +P  +G  ++ IK N     I   P +  VN PN   ++ +YGPGL   VA+ P  F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+ +I  SP+
Sbjct: 1745 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1869          

HSP 6 Score: 66.2402 bits (160), Expect = 7.202e-10
Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   I  SPF   + DD  RR
Sbjct: 1789 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1880          

HSP 7 Score: 61.2326 bits (147), Expect = 2.605e-8
Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351
            P  V   G  L +   N  N F V T G   G L I +EGPS++++S  D K G   V Y   + G+Y   I+++   IP SPFR+ V D V+             S+V++   G  T+++  + +      S   I  L   VT P G
Sbjct: 1329 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1465          

HSP 8 Score: 60.4622 bits (145), Expect = 3.899e-8
Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1026 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1124          

HSP 9 Score: 59.3066 bits (142), Expect = 8.518e-8
Identity = 84/337 (24.93%), Postives = 134/337 (39.76%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873
            ++E GD S+    V   G  L +G     + F+V T     G L++ +EGPSK +I   D + G   VSY  T PG Y+ +I F    +P SPF   V  +  V   I  +   P + S               VG     ++  PEI    L   V  P G      I  + + ++   F+       G++ +            S K + E++ GS    T         + PL      + + A G GL++        F I  W            L + ++GPSK +IS  +  +G     Y+    G Y + I ++++ HIP SPF + ++
Sbjct: 1961 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS---------------VGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFV---PQETGIHTV------------SVKYRGEHVPGSPFQFT---------VGPLGEGGA-EKVKAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDE-HIPQSPFLVPIV 2246          

HSP 10 Score: 58.5362 bits (140), Expect = 1.496e-7
Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T DG+ I GSPF + V +  D        P   +     + Q  + ++ K G  P    V+    T+
Sbjct: 1360 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1467          

HSP 11 Score: 55.0694 bits (131), Expect = 1.696e-6
Identity = 37/94 (39.36%), Postives = 50/94 (53.19%), Query Frame = 3
Query: 5595 NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867
            ++ AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y N  HI GSPF  KIT
Sbjct: 1788 SVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1874          

HSP 12 Score: 54.6842 bits (130), Expect = 2.692e-6
Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
            N +  S IP   G   + IKKN     I N P  + V          + ++GPGL          FI+DT  +    +  ++EGPSK  I+  ++ +G+  ++Y    PG+Y +SI   +E++  SP++  ++   +V E
Sbjct: 1925 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2062          
BLAST of Filamin A vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165])

HSP 1 Score: 163.31 bits (412), Expect = 2.301e-39
Identity = 137/507 (27.02%), Postives = 229/507 (45.17%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-----EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP----SKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++     ++  FS    Q ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K+       L W+ +K+    I N S  W  G A+G +V++C   LC D   W+    + NA+ AM+ A     +PQ++ P EIID +  + ++MTY+SQF          L+ + N K     +     ++  GN     A  + + IS                G  ++L+ I                D  GN  +    GN  K+   S   +P ++G   + +        I   PF V V       + + + GPGL   G++A+ P  F + T G+    IG  +  P    +  ++   + GN     TY  +  G + ++I    E    SPY + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFS----QMQLENVSVALEFLERENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWEDEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGLGVEPTGNMVKRSAPFTVETIS---------------AGTGEVLVYI---------------EDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFA--GQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSIGEACNPNACRANGRGLQPKGVRIRETADFRVDTKAA 483          

HSP 2 Score: 114.775 bits (286), Expect = 1.405e-24
Identity = 103/321 (32.09%), Postives = 141/321 (43.93%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRI---LHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y   I FN   IP SPF + +   +DD  R     L   +K +  +   ++  G    I          V SP      CFVTE        P K   +   ++          G++ ID   F G  + G  +KV++                  Q  +P +V        AYGDGL+  T  +++ F I   N S++      +L VTI+GPSKV + C E   GY   Y P+  G+Y IG+ Y    HI GSPFK  V
Sbjct: 2203 GPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATSDDARRLTVTSLQSGLKVNQPASFAIRLNGARGKIDA-------KVHSPSGAVEECFVTE------LEPDKYAVRFMPREN---------GIHMIDV-KFNGSHVPGSPFKVRVGEAG--------------QEGDPGLVT-------AYGDGLETGTTGKQSEFII---NTSKA---GPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKV 2473          

HSP 3 Score: 82.4185 bits (202), Expect = 8.816e-15
Identity = 48/142 (33.80%), Postives = 77/142 (54.23%), Query Frame = 3
Query: 1062 FSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            F   P+  G + + I    +   I   PF V V L      + ++GPGLY  +A     F++++ GS+   +GF++EGPS+ KIEC + G+GS  + Y    PG Y + IM ++E+I +SPY  +I  ++   +  KVK  G
Sbjct:  505 FEYYPLTPGKYVVAITWGGH--HIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYG 644          

HSP 4 Score: 70.4774 bits (171), Expect = 3.652e-11
Identity = 89/334 (26.65%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDI-----CSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PGNLA+    +  SKAE++  D K G Y V+Y     G Y  A+ +    +P  P R+ V   V+   + K   P I       E       ++ S+   G N   HV +         +T P G S+ + ++      N DG  ++       G + I       D+  P+   K+          T  C  D               + A G GL +A  N+ N F         S+I +      L +T++GPS+ ++SC ++ +G     Y P V G Y + ITY  + HIPGSPF++ V
Sbjct: 1125 PSKVIATGPGLEHGKVGEAGLIHVDCSQAGPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKI-KVFGPGIEEKGVFREATTDFTVDAKSLTKTGGN---HVKTK--------ITNPSGASTDYLLR-----DNGDGTYYVEYTPFEKGAHAIKVT--YDDEPVPNSPFKV--------GVTEGCYPD--------------RVKAQGAGLTEALTNKPNLF---------SVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGE-HIPGSPFRVPV 1407          

HSP 5 Score: 70.4774 bits (171), Expect = 4.285e-11
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   +S   +P  +G  ++ IK N     I   P +  VN PN   ++ +YGPGL   VA+ P  F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+ +I  SP+
Sbjct: 1737 KDGTVSIRYVPTETGLHELAIKCN--GAHIPESPLQFFVNYPNTG-SVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPF 1861          

HSP 6 Score: 66.6254 bits (161), Expect = 6.577e-10
Identity = 37/92 (40.22%), Postives = 46/92 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   I  SPF   + DD  RR
Sbjct: 1781 VSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRR 1872          

HSP 7 Score: 65.0846 bits (157), Expect = 1.788e-9
Identity = 80/307 (26.06%), Postives = 116/307 (37.79%), Query Frame = 3
Query: 4971 FVVHTSGKIPGNLAICIEGPS--KAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPF--KIT 5867
            FVV  +    G +   I GP   + E   ++   G Y + Y     G YV  + F   DIP+SPF + V                           N  S +P    + F + + EI      V  P G ++   I       NKDG +++              ++  + G             L    + C+      +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y N  HI GSPF  KIT
Sbjct: 1625 FVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMVG------------------------SMNGLSFRPFDLVIPFAIRTGEITG---DVHMPSGKTAPADI-----VDNKDGTVSI-------------RYVPTETG-------------LHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKY-NDTHIAGSPFIAKIT 1866          

HSP 8 Score: 61.2326 bits (147), Expect = 2.262e-8
Identity = 46/149 (30.87%), Postives = 67/149 (44.97%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351
            P  V   G  L +   N  N F V T G   G L I +EGPS++++S  D K G   V Y   + G+Y   I+++   IP SPFR+ V D V+             S+V++   G  T+++  + +      S   I  L   VT P G
Sbjct: 1320 PDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDP------------SKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRG 1456          

HSP 9 Score: 60.8474 bits (146), Expect = 3.590e-8
Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1017 VPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPF 1115          

HSP 10 Score: 58.9214 bits (141), Expect = 1.400e-7
Identity = 29/108 (26.85%), Postives = 50/108 (46.30%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTI 2384
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T DG+ I GSPF + V +  D        P   +     + Q  + ++ K G  P    V+    T+
Sbjct: 1351 GGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTV 1458          

HSP 11 Score: 55.8398 bits (133), Expect = 1.125e-6
Identity = 39/119 (32.77%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228
            ++E GD S+    V   G  L +G     + F+V T     G L++ +EGPSK +I   D + G   VSY  T PG Y+ +I F    +P SPF   V  +  V   I  +   P + S
Sbjct: 1953 QSEIGDASK----VKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKESITRRRKAPSVAS 2067          

HSP 12 Score: 54.6842 bits (130), Expect = 2.317e-6
Identity = 39/140 (27.86%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
            N +  S IP   G   + IKKN     I N P  + V          + ++GPGL          FI+DT  +    +  ++EGPSK  I+  ++ +G+  ++Y    PG+Y +SI   +E++  SP++  ++   +V E
Sbjct: 1917 NHIGISFIPREVGEHLVSIKKN--GRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMGEGRVKE 2054          

HSP 13 Score: 52.7582 bits (125), Expect = 8.887e-6
Identity = 37/141 (26.24%), Postives = 72/141 (51.06%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG------LENKNTKSFIIDSRNS 1532
            + N PF+V V        + + G GL  ++ + P +F + T G+    +G ++EGPS++K+ C +  +GS  + Y+  + G Y ++I  + E+I  SP+ + +     V +  KVK+ G      +  K  + F +D+  +
Sbjct: 1305 VPNSPFKVGVTEGCYPDRVKAQGAGLTEALTNKPNLFSVITRGAGIGGLGITVEGPSESKMSCKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPV---KDVVDPSKVKISGPGLGTAVRAKIPQQFTVDTSKA 1442          
BLAST of Filamin A vs. Ensembl Mouse
Match: Flnb (filamin, beta [Source:MGI Symbol;Acc:MGI:2446089])

HSP 1 Score: 163.696 bits (413), Expect = 1.684e-39
Identity = 135/502 (26.89%), Postives = 227/502 (45.22%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++ +   E +  +  V    DKN                  S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + +    + I  SP+ + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMVFVEDPEGNKEEARVTPDSDKN---------------KTYSVEYLPKVTGLHKVIVLFA--GQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAA 482          

HSP 2 Score: 98.5969 bits (244), Expect = 9.068e-20
Identity = 94/321 (29.28%), Postives = 139/321 (43.30%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV-ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V A   + R L         + + +Q  G   + +P    +  + +  +I   +  V  P G      + ++        FI       G++ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI   N +++      +L VTI+GPSKV++ C E   GY   Y P+  G Y IG+ Y    HI  SPFK  V
Sbjct: 2194 HKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCL---------TVLSLQESGLKVN-QPASFAIRLNGAKGKI---DAKVHSPSGAVEECHVSELEPDKYAVRFI---PHENGIHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGAGLETGTTGIQSEFFI---NTTQA---GPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKV 2471          

HSP 3 Score: 85.5001 bits (210), Expect = 8.585e-16
Identity = 79/319 (24.76%), Postives = 135/319 (42.32%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD NRR          CS+V++ +            + +  +S  ++  L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDD-NRR----------CSQVKLGS----------AADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGQGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089          

HSP 4 Score: 81.6481 bits (200), Expect = 1.243e-14
Identity = 88/317 (27.76%), Postives = 129/317 (40.69%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      I     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V       +P +  E  +  +  N    KP    + F V   EI      V  P G  +   I       NKDG + V                  +  P+ +V +  +H   R + +         +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGT---VHMPSGKKATPEI-----VDNKDGTVTV------------------RYAPT-EVGLHEMHIKYRGSHIP-------ESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911          

HSP 5 Score: 72.7886 bits (177), Expect = 5.794e-12
Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI--VKSNKVDEIKKVKVIGLENK-----NTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQR 1745
            SF   P   G + + +    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I     +   ++ +    GLE       N   FI+D +++    P  +   D  G   +  + + ++  Y     PL   +  I  V +  V +   PY ++    +  Q+
Sbjct:  512 SFEYYPSTPGKYSVAVTWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAG-SAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVV-WGGVNIPHSPYRVNIGQGSHPQK 744          

HSP 6 Score: 71.2478 bits (173), Expect = 1.685e-11
Identity = 84/342 (24.56%), Postives = 145/342 (42.40%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +   R               +     + ++  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1995 VQSEIGDARR----AKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVR-------------ESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGIPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPDSPYLVPVIA-PSDD 2286          

HSP 7 Score: 65.855 bits (159), Expect = 8.177e-10
Identity = 37/93 (39.78%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  VH  G  L + F N +N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++  V IP SPFR+   D V+
Sbjct: 1328 PSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVD 1420          

HSP 8 Score: 63.929 bits (154), Expect = 2.909e-9
Identity = 40/137 (29.20%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   N+
Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKYR--GSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNR 1913          

HSP 9 Score: 62.003 bits (149), Expect = 1.203e-8
Identity = 79/330 (23.94%), Postives = 128/330 (38.79%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKP-----DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P  + V   ++   + K   P     D+  E       +S  +  VG + I   +++P   +  CFV +   G+      ++  T  + GF  + V    + + N  F   + +   PS       +H                              A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++
Sbjct: 1133 PSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGI-KAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTY-----QVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPS------RVH------------------------------AQGPGLKEAFTNKSNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-VHIPGSPFRV 1413          

HSP 10 Score: 60.077 bits (144), Expect = 3.902e-8
Identity = 92/415 (22.17%), Postives = 161/415 (38.80%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKN------TKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIE--LSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            + I N PF+V V    +   + + GPGL  +  +   VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+    V S  V +  KVK+ G    +       +SF +DS  +    P +V      G+     +V   +  +     P       IV V Y   ++   P+ +     YD+++        S +       +E    D  DA E  L+VQ          + +   K    +  T  +++  T+   +I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++  ++
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGP-YIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVE-FAIDARDAGEGLLAVQ----------ITDQEGKP---QRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD 1706          

HSP 11 Score: 59.3066 bits (142), Expect = 7.085e-8
Identity = 36/120 (30.00%), Postives = 62/120 (51.67%), Query Frame = 3
Query: 1068 LIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
             IP   G F + +  + +   +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1006 FIPREEGLFAVDVTYDGHP--VPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 55.8398 bits (133), Expect = 7.834e-7
Identity = 55/212 (25.94%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G+V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I DSPY + ++  +  D+ + + V+ L+    K
Sbjct: 2099 ITRTSRAPAVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPS--DDARCLTVLSLQESGLK 2301          

HSP 13 Score: 53.1434 bits (126), Expect = 6.034e-6
Identity = 89/350 (25.43%), Postives = 129/350 (36.86%), Query Frame = 3
Query: 4881 TESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIF-HVSSPEILNLNCFVTEP-----HGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIG--PSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDV-------TIDGPSKVQISCIEDING---YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            T    L   P +V   G  L  G V    +F + T G   G L + +EGP +A+I   D   G   VSY  T PGEY   I F +V IP SPF+                     +++EM    + + +   G  L    V  P IL ++C    P        S      ++S  +NKDG   +     T G+Y +    + G+ +   P+W VK+E                     P I       I A+G G++   V R+          ++  +   P   V        I  PS     C    N    Y   Y P   G + + +TY +   IP SPFK+ V
Sbjct: 1031 TVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFK---------------------ADIEM--PFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTM-KYGGELVPHFPAW-VKVE---------------------PAIDT---SGIKAFGPGIEGKDVFRE--------ATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDD-VPIPNSPFKVAV 1322          
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556])

HSP 1 Score: 152.525 bits (384), Expect = 3.803e-38
Identity = 92/244 (37.70%), Postives = 140/244 (57.38%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            ++  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  +NNA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF
Sbjct:   11 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQF 252          
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556])

HSP 1 Score: 159.073 bits (401), Expect = 4.086e-38
Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            ++  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  +NNA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+   ++   ++ P+  K     +    G+ +   +Y   + G++ + +      I  SPY++ + ++
Sbjct:   23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477          

HSP 2 Score: 106.686 bits (265), Expect = 3.536e-22
Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +  V    +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       G+Y ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2231 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508          

HSP 3 Score: 81.2629 bits (199), Expect = 1.774e-14
Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + S T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD        VN    +I AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y+++ HIPGSPF   V  D +  ++H
Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1954          

HSP 4 Score: 76.2554 bits (186), Expect = 4.906e-13
Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +       ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +      DT + D    T      +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.707 bits (169), Expect = 4.744e-11
Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  +G +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G++ +            S K K +++ GS    T         + PL     ++ + A G GL++A V     F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323          

HSP 6 Score: 68.9366 bits (167), Expect = 9.773e-11
Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N   IP SPF   V  D + R+ H  V
Sbjct: 1864 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1957          

HSP 7 Score: 67.0106 bits (162), Expect = 3.116e-10
Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583
             F   P + G++ + I        I   PF V V        + ++GPGL G +      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I ++ +     +VK    GLE           F +D++++  + P  V+  D  G S
Sbjct:  539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718          

HSP 8 Score: 59.6918 bits (143), Expect = 5.800e-8
Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    I +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  N+++I  SP++  +
Sbjct: 1816 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1944          

HSP 9 Score: 58.9214 bits (141), Expect = 8.394e-8
Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK   +    ++   P DV      G+  +   V   +K  F ++C       L+V V
Sbjct: 2378 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2586          
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556])

HSP 1 Score: 159.073 bits (401), Expect = 4.086e-38
Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            ++  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  +NNA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+   ++   ++ P+  K     +    G+ +   +Y   + G++ + +      I  SPY++ + ++
Sbjct:   23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477          

HSP 2 Score: 106.686 bits (265), Expect = 3.536e-22
Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +  V    +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       G+Y ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2231 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508          

HSP 3 Score: 81.2629 bits (199), Expect = 1.774e-14
Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + S T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD        VN    +I AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y+++ HIPGSPF   V  D +  ++H
Sbjct: 1671 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1954          

HSP 4 Score: 76.2554 bits (186), Expect = 4.906e-13
Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +       ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +      DT + D    T      +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.707 bits (169), Expect = 4.744e-11
Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  +G +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G++ +            S K K +++ GS    T         + PL     ++ + A G GL++A V     F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2033 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2323          

HSP 6 Score: 68.9366 bits (167), Expect = 9.773e-11
Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N   IP SPF   V  D + R+ H  V
Sbjct: 1864 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1957          

HSP 7 Score: 67.0106 bits (162), Expect = 3.116e-10
Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583
             F   P + G++ + I        I   PF V V        + ++GPGL G +      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I ++ +     +VK    GLE           F +D++++  + P  V+  D  G S
Sbjct:  539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718          

HSP 8 Score: 59.6918 bits (143), Expect = 5.800e-8
Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    I +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  N+++I  SP++  +
Sbjct: 1816 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1944          

HSP 9 Score: 58.9214 bits (141), Expect = 8.394e-8
Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK   +    ++   P DV      G+  +   V   +K  F ++C       L+V V
Sbjct: 2378 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2586          
BLAST of Filamin A vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556])

HSP 1 Score: 158.688 bits (400), Expect = 4.450e-38
Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            ++  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  +NNA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+   ++   ++ P+  K     +    G+ +   +Y   + G++ + +      I  SPY++ + ++
Sbjct:   23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477          

HSP 2 Score: 106.301 bits (264), Expect = 3.816e-22
Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +  V    +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       G+Y ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2239 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516          

HSP 3 Score: 80.8777 bits (198), Expect = 1.835e-14
Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + S T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD        VN    +I AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y+++ HIPGSPF   V  D +  ++H
Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1962          

HSP 4 Score: 76.2554 bits (186), Expect = 5.076e-13
Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +       ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +      DT + D    T      +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.707 bits (169), Expect = 5.162e-11
Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  +G +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G++ +            S K K +++ GS    T         + PL     ++ + A G GL++A V     F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331          

HSP 6 Score: 68.5514 bits (166), Expect = 1.003e-10
Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N   IP SPF   V  D + R+ H  V
Sbjct: 1872 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1965          

HSP 7 Score: 67.0106 bits (162), Expect = 3.448e-10
Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583
             F   P + G++ + I        I   PF V V        + ++GPGL G +      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I ++ +     +VK    GLE           F +D++++  + P  V+  D  G S
Sbjct:  539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718          

HSP 8 Score: 59.6918 bits (143), Expect = 6.050e-8
Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    I +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  N+++I  SP++  +
Sbjct: 1824 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1952          

HSP 9 Score: 58.9214 bits (141), Expect = 8.905e-8
Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK   +    ++   P DV      G+  +   V   +K  F ++C       L+V V
Sbjct: 2386 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2594          
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|O75369|FLNB_HUMAN (Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2)

HSP 1 Score: 164.081 bits (414), Expect = 8.203e-39
Identity = 136/502 (27.09%), Postives = 228/502 (45.42%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++              VE  D  GN  +     +  K+   S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + I    + I  SP+ + + ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMV-------------FVE--DPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFA--GQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAA 482          

HSP 2 Score: 90.8929 bits (224), Expect = 1.288e-16
Identity = 97/325 (29.85%), Postives = 135/325 (41.54%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V   +DD  R  +    +  +       N+  S +I+  G    +   V SP      C V+E        P K           +       GV+ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI       +      +L VTI+GPSKV++ C E   GY   Y P+  G Y I + Y    HI GSPFK  V
Sbjct: 2194 HKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGL-----KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSE------LEPDKYA---------VRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGTGLEGGTTGIQSEFFI------NTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKV 2471          

HSP 3 Score: 83.9593 bits (206), Expect = 1.746e-14
Identity = 77/319 (24.14%), Postives = 134/319 (42.01%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD  R           CS+V++ +            + +  +S  ++ +L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRR-----------CSQVKLGS----------AADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGRGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089          

HSP 4 Score: 81.6481 bits (200), Expect = 8.270e-14
Identity = 89/319 (27.90%), Postives = 131/319 (41.07%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      +     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V       +P +  E  +  +  N    KP    + F V   EI      V  P G ++   I       NKDG + V +A T +G++ +    ++G  I  S                           PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGE---VHMPSGKTATPEI-----VDNKDGTVTVRYAPTEVGLHEMHI-KYMGSHIPES---------------------------PLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911          

HSP 5 Score: 72.7886 bits (177), Expect = 3.919e-11
Identity = 87/342 (25.44%), Postives = 146/342 (42.69%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +         VK  I           + S+  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1995 VQSEIGDARR----AKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE-------GRVKESI------TRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPESPYLVPVIA-PSDD 2286          

HSP 6 Score: 71.2478 bits (173), Expect = 1.292e-10
Identity = 87/334 (26.05%), Postives = 136/334 (40.72%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNR-RILHKHVK-PDICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINP---LIVNEIYQ--NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L  G V       V  S   PG L +    +  +KAE+S  + K G Y V+Y     G Y   + +    +PH P R+ V  A D +R ++    ++  D+  E       +S  +  VG + I  H+++P   +  CFVT+                 N DG           Y +++  F                   L    ++ D D+ I N    + V E  Q   + A G GL++A  N+ N F +               L +T++GPS+ +I+C ++ +G     YIP   G Y + ITY    HIPGSPF++ V
Sbjct: 1133 PSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTD-----------------NADG----------TYQVEYTPF----------------EKGLHVVEVTYD-DVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIG------GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGG-AHIPGSPFRVPV 1415          

HSP 7 Score: 70.0922 bits (170), Expect = 2.777e-10
Identity = 42/127 (33.07%), Postives = 66/127 (51.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +F   P   G + I I    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I
Sbjct:  512 AFEYYPSTPGRYSIAITWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFI 636          

HSP 8 Score: 67.781 bits (164), Expect = 1.303e-9
Identity = 90/424 (21.23%), Postives = 169/424 (39.86%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPI 2276
            + I N PF+V V    +   + + GPGL  +  + P VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+ + +     V +  KVK+       G+  +  +SF +DS  +    P +V      G+     +V   +  +     P      + V V Y   ++   P+ +     YD+++        S++       ++      +DA +     L V   +      + K+ I+ H+  + +   T+  I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++  ++   T V  + +P+
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPV---KDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYM-VSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDF----AIDARDAGEGLLAVQITDQ---EGKPKRAIV-HDNKDGTYAVTY--IPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAV--EEAPV 1717          

HSP 9 Score: 62.3882 bits (150), Expect = 6.220e-8
Identity = 36/93 (38.71%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L + F N  N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1328 PSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVD 1420          

HSP 10 Score: 62.003 bits (149), Expect = 8.705e-8
Identity = 39/137 (28.47%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   ++
Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKY--MGSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR 1913          

HSP 11 Score: 58.9214 bits (141), Expect = 7.544e-7
Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1025 VPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 12 Score: 56.6102 bits (135), Expect = 2.943e-6
Identity = 54/212 (25.47%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I +SPY + ++  +  D+ +++ V+ L+    K
Sbjct: 2099 ITRTSRAPSVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPS--DDARRLTVMSLQESGLK 2301          
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|Q80X90|FLNB_MOUSE (Filamin-B OS=Mus musculus OX=10090 GN=Flnb PE=1 SV=3)

HSP 1 Score: 163.696 bits (413), Expect = 1.178e-38
Identity = 135/502 (26.89%), Postives = 227/502 (45.22%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP-SKTKIE--CANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS 1532
            KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+ +K+    I N +  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     +PQ++ P EII     + ++MTY+SQF          L+ + N K     +     I+  GN     A  + D IS                G+ D+++ +   E +  +  V    DKN                  S   +P ++G   + +        I   PF V V+      + + + GPGL   G++A+ P  F + T G+    IG  +E P  K  +E    + GN      Y  + PG + + +    + I  SP+ + I ++   +  +     ++  G+  + T  F +D++ +
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPK---KARAYGRGIEPTGNMVKQPAKFTVDTIS---------------AGQGDVMVFVEDPEGNKEEARVTPDSDKN---------------KTYSVEYLPKVTGLHKVIVLFA--GQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAA 482          

HSP 2 Score: 98.5969 bits (244), Expect = 6.343e-19
Identity = 94/321 (29.28%), Postives = 139/321 (43.30%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV-ADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D K G   VSY    PG Y  +I FN   IP SP+ + V A   + R L         + + +Q  G   + +P    +  + +  +I   +  V  P G      + ++        FI       G++ ID        +G  +KV++                  Q  NP +V+       AYG GL+  T   ++ FFI   N +++      +L VTI+GPSKV++ C E   GY   Y P+  G Y IG+ Y    HI  SPFK  V
Sbjct: 2194 HKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCL---------TVLSLQESGLKVN-QPASFAIRLNGAKGKI---DAKVHSPSGAVEECHVSELEPDKYAVRFI---PHENGIHTIDVKFNGSHVVGSPFKVRVGEPG--------------QAGNPALVS-------AYGAGLETGTTGIQSEFFI---NTTQA---GPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKV 2471          

HSP 3 Score: 85.5001 bits (210), Expect = 6.005e-15
Identity = 79/319 (24.76%), Postives = 135/319 (42.32%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G  N    F + T     G L + IEGPSKAEIS +D K G   V+Y  T+PG+Y   + +N   IP SPF   + DD NRR          CS+V++ +            + +  +S  ++  L   +  P G      +K++                IG+      +F+  ++G    V I+     + ++ +S    I ++   I +     +  YG GL +      + F +      ++       + + ++GPSKV I   +  +G     Y P V G+Y +   ++++ H+PGSPF + +
Sbjct: 1824 VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDD-NRR----------CSQVKLGS----------AADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNH------------IGI------SFIPREVGEHL-VSIKKNGNHVANSPVS----IMVVQSEIGDARRAKV--YGQGLSEGRTFEMSDFIV------DTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADE-HVPGSPFTVKI 2089          

HSP 4 Score: 81.6481 bits (200), Expect = 8.698e-14
Identity = 88/317 (27.76%), Postives = 129/317 (40.69%), Query Frame = 3
Query: 4971 FVV--HTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV-------KPDICSEVEMQ-NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV   T+GK      I     ++AE   ++ + G Y + Y    PG YV  + F  VDIP+SPF +   D     +    V       +P +  E  +  +  N    KP    + F V   EI      V  P G  +   I       NKDG + V                  +  P+ +V +  +H   R + +         +PL     Y N   + AYG GL     N+   F I   +  E        LD+ I+GPSK +ISCI++ +G     Y+P + G Y I + Y++K HIPGSPF   +  D
Sbjct: 1636 FVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGT---VHMPSGKKATPEI-----VDNKDGTVTV------------------RYAPT-EVGLHEMHIKYRGSHIP-------ESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEG------GLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDK-HIPGSPFTAKITDD 1911          

HSP 5 Score: 72.7886 bits (177), Expect = 4.053e-11
Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI--VKSNKVDEIKKVKVIGLENK-----NTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQR 1745
            SF   P   G + + +    +   I   PF V V        + ++GPGL+G +      F++++ GS+   +GF++EGPS+ KIE  +  +GS  + Y    PG Y + IM ++E+I DSPY   I     +   ++ +    GLE       N   FI+D +++    P  +   D  G   +  + + ++  Y     PL   +  I  V +  V +   PY ++    +  Q+
Sbjct:  512 SFEYYPSTPGKYSVAVTWGGH--HIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAG-SAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVV-WGGVNIPHSPYRVNIGQGSHPQK 744          

HSP 6 Score: 71.2478 bits (173), Expect = 1.178e-10
Identity = 84/342 (24.56%), Postives = 145/342 (42.40%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +      V G+ L +G     + F+V T     G +++ +EGPSK +I   D + G   VSY  T+PG Y+ +  F    +P SPF + ++ +   R               +     + ++  VG     ++  PEI   +++  VT P G  +   I  M K S+   F+      +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++        F I  W            L + ++GPSK +I+  +  NG     YI    G Y + I ++++ HIP SP+ + V+  P+ D
Sbjct: 1995 VQSEIGDARR----AKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVR-------------ESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFV---PQEMGVHTV------------SVKYRGQHVTGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERGEAGIPAEFSI--WTREAG----AGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDE-HIPDSPYLVPVIA-PSDD 2286          

HSP 7 Score: 65.855 bits (159), Expect = 5.720e-9
Identity = 37/93 (39.78%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  VH  G  L + F N +N F V T G   G L I +EGPS+++I+  D K G     Y    PG+Y   I++  V IP SPFR+   D V+
Sbjct: 1328 PSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVD 1420          

HSP 8 Score: 63.929 bits (154), Expect = 2.034e-8
Identity = 40/137 (29.20%), Postives = 68/137 (49.64%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   ++    P   G  ++ IK       I   P +  VN PN   ++ +YGPGL   VA+    F I+  +  +  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  N+++I  SP++  I   N+
Sbjct: 1780 KDGTVTVRYAPTEVGLHEMHIKYR--GSHIPESPLQFYVNYPNSG-SVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNR 1913          

HSP 9 Score: 60.077 bits (144), Expect = 2.729e-7
Identity = 92/415 (22.17%), Postives = 161/415 (38.80%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKN------TKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI---DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIE--LSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFGLILYGTSLSG----------RPIKKGE---CQVVQIDLDRSIQGG-SIGFVLEGP----------------IETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSE 2237
            + I N PF+V V    +   + + GPGL  +  +   VF + T G+    +G ++EGPS++KI C +  +GS    Y    PG Y ++I     +I  SP+    V S  V +  KVK+ G    +       +SF +DS  +    P +V      G+     +V   +  +     P       IV V Y   ++   P+ +     YD+++        S +       +E    D  DA E  L+VQ          + +   K    +  T  +++  T+   +I  K G  + G +  G          R  + G+   C      +  +++ G  +GFV++                   E +      +DG Y I +     G Y ++V   G  I  SPF++  ++
Sbjct: 1311 VPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGL-APLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGP-YIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVE-FAIDARDAGEGLLAVQ----------ITDQEGKP---QRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD 1706          

HSP 10 Score: 59.3066 bits (142), Expect = 4.956e-7
Identity = 36/120 (30.00%), Postives = 62/120 (51.67%), Query Frame = 3
Query: 1068 LIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
             IP   G F + +  + +   +   P+ V  +LP     + ++GPGL G +   P  F +DT G+        +EGP + KIEC++ G+G+  ++Y    PG Y ++I+  E +I  SP+
Sbjct: 1006 FIPREEGLFAVDVTYDGHP--VPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPF 1123          

HSP 11 Score: 55.8398 bits (133), Expect = 5.480e-6
Identity = 55/212 (25.94%), Postives = 95/212 (44.81%), Query Frame = 3
Query:  882 IRQLDKPPDVIKDGRV-DLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            I +  + P V   G + DL +KIP I    + ++       +G+V +         S+ + F  +P   G   + +K       +   PF+  V    +     + + GPGL    A  P  F I         +  ++EGPSK +I   +  NGS  ++Y A  PG Y++SI  N+E+I DSPY + ++  +  D+ + + V+ L+    K
Sbjct: 2099 ITRTSRAPAVATVGSICDLNLKIPEIN---SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRF--VPQEMGVHTVSVKYR--GQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPS--DDARCLTVLSLQESGLK 2301          
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|Q8BTM8|FLNA_MOUSE (Filamin-A OS=Mus musculus OX=10090 GN=Flna PE=1 SV=5)

HSP 1 Score: 158.688 bits (400), Expect = 3.113e-37
Identity = 132/492 (26.83%), Postives = 228/492 (46.34%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            ++  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  +NNA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+   ++   ++ P+  K     +    G+ +   +Y   + G++ + +      I  SPY++ + ++
Sbjct:   23 SRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA 477          

HSP 2 Score: 106.301 bits (264), Expect = 2.669e-21
Identity = 100/326 (30.67%), Postives = 142/326 (43.56%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +  V    +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       G+Y ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2239 HKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGIYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGSPAEFIVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516          

HSP 3 Score: 80.8777 bits (198), Expect = 1.284e-13
Identity = 85/324 (26.23%), Postives = 143/324 (44.14%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + S T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD        VN    +I AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y+++ HIPGSPF   V  D +  ++H
Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPSITDNKDGTVTVRYSPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVDY-------VN--CGHITAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQ-HIPGSPFTARVTGDDSMRMSH 1962          

HSP 4 Score: 76.2554 bits (186), Expect = 3.550e-12
Identity = 100/456 (21.93%), Postives = 175/456 (38.38%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDT-INDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +       ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +      DT + D    T      +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VSPSGAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYK----VEYTPYEEG----VHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.707 bits (169), Expect = 3.611e-10
Identity = 90/345 (26.09%), Postives = 147/345 (42.61%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  +G +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G++ +            S K K +++ GS    T         + PL     ++ + A G GL++A V     F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGMHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEVGVPAEFGI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331          

HSP 6 Score: 68.5514 bits (166), Expect = 7.013e-10
Identity = 39/94 (41.49%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N   IP SPF   V  D + R+ H  V
Sbjct: 1872 GPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKV 1965          

HSP 7 Score: 67.0106 bits (162), Expect = 2.412e-9
Identity = 52/183 (28.42%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNSTFEMPPDVECFDKLGVS 1583
             F   P + G++ + I        I   PF V V        + ++GPGL G +      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I ++ +     +VK    GLE           F +D++++  + P  V+  D  G S
Sbjct:  539 GFEYYPTIPGTYTVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAG-KAPLRVQVQDNEGCS 718          

HSP 8 Score: 59.6918 bits (143), Expect = 4.232e-7
Identity = 36/132 (27.27%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    I +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  N+++I  SP++  +
Sbjct: 1824 KDGTVTVRYSPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1952          

HSP 9 Score: 58.9214 bits (141), Expect = 6.229e-7
Identity = 60/218 (27.52%), Postives = 96/218 (44.04%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK   +    ++   P DV      G+  +   V   +K  F ++C       L+V V
Sbjct: 2386 DKYAVRFIPRENGIYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLVGV 2594          
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|P21333|FLNA_HUMAN (Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4)

HSP 1 Score: 158.303 bits (399), Expect = 5.203e-37
Identity = 136/514 (26.46%), Postives = 232/514 (45.14%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSDQ-------QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
             +  EM  T+ ++ +     KI++  FTRW N  LK  +K I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   DE  K        L W+ +KL    I N S  W SG A+G +V++C   LC D   W++S  + NA+ AM+ A     IPQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN     A  + +  S                G+ ++L+ +                D  G+  +     N  K+   S   +P ++G+  + +        I   PF V V+      + + + GPGL   G++A+    F + T G+         Q     +G  + ++E    G+ +   +Y   + G++ + +      I  SPY++ + ++      + V   GL+ K  +
Sbjct:   23 TRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH--RKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNMVKKRAEFTVETRS---------------AGQGEVLVYV---------------EDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFA--GQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEAR--GDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGR-GLQPKGVR 496          

HSP 2 Score: 106.301 bits (264), Expect = 2.538e-21
Identity = 100/326 (30.67%), Postives = 141/326 (43.25%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN--RRILHKHVKPDICSEVEMQNKGN-STSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +       +F + T     G LAI +EGPSKAEISF D+K G   V+Y V  PG+Y  ++ FN+  IP SPF + VA      RR+    ++    S +++    + + S+      +   V SP      C+VTE                 ++D + +       GVY ID   F G  I G  +K+++ E  HG                +P +V+       AYG GL+         F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2239 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQE---SGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTE----------------IDQDKYAVRFIPRENGVYLIDV-KFNGTHIPGSPFKIRVGEPGHGG---------------DPGLVS-------AYGAGLEGGVTGNPAEFVVNTSNAGAG------ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516          

HSP 3 Score: 79.7221 bits (195), Expect = 3.610e-13
Identity = 83/327 (25.38%), Postives = 141/327 (43.12%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRIT-VADD---VNRRILHKHVKPDICSEVEMQ------------NKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN---ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    S+ ++  ++ + G + + Y    PG+YV  + F    +P+SPF++T +A D   V   +  + + P        Q            N  + TS++P    + F +   EI      V  P G      + + + T NKDG + V    S  G++ +D              ++ +N+H  +  + L   VD            Y N   + AYG GL    VN+   F +   N  ++    E  L + I+GPSK +ISC ++ +G     Y+P++ G Y I + Y N+ H+PGSPF   V  D +  ++H
Sbjct: 1679 AGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGE---VRMPSG-----KVAQPTITDNKDGTVTVRYAPSEAGLHEMD--------------IRYDNMH--IPGSPLQFYVD------------YVNCGHVTAYGPGLTHGVVNKPATFTV---NTKDA---GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKY-NEQHVPGSPFTARVTGDDSMRMSH 1962          

HSP 4 Score: 78.1814 bits (191), Expect = 9.410e-13
Identity = 99/456 (21.71%), Postives = 176/456 (38.60%), Query Frame = 3
Query:  993 VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPY------AID------YYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLI-IKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDL-DRSIQGGSIG----FVLE--------------GPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDT 2249
            V  +G    C         N +    +P   G +++ +  +   + +   PF +    P K   + ++GPGL G  A  P  F +DT G+        +EGP + ++EC + G+G+  ++Y    PG Y ++I+  + +I  SP+   +V      ++ K    GLE         F +D S   + E+   +E   + G+ +   +    +  +     PL       V + Y    V  FP       A+D      Y    EGQ    + +T  S+  + L       V A   +        + +  V  R   +  +++  +EE        +D  +      +S    P+ +G C   ++ +    IQ G+      F +E              GP E ++ C    DG   +++ P  AG Y L VT  G  + GSPF + V + +D 
Sbjct: 1009 VGPSGAAVPCKVEPGLGADNSV-VRFLPREEGPYEVEVTYD--GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKV-KCSGPGLERATAGEVGQFQVDCSSAGSAEL--TIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA-YTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPS----GNLTETYVQDRGDGMYKVEYTPYEEG----LHSVDVTYDGSPVPSSPFQVPVTEG-CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDA 1448          

HSP 5 Score: 69.3218 bits (168), Expect = 4.846e-10
Identity = 39/98 (39.80%), Postives = 51/98 (52.04%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHV 5210
            V   G  L  G VN    F V+T     G L++ IEGPSKAEIS  D + G   VSY   +PG+Y   + +N+  +P SPF   V  D + R+ H  V
Sbjct: 1868 VTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKV 1965          

HSP 6 Score: 69.3218 bits (168), Expect = 5.139e-10
Identity = 90/345 (26.09%), Postives = 145/345 (42.03%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E GD S+    V V G+ L +G      +F++ T     G L++ IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  V   I  +   P               S+  VG +    +  PE  I ++   VT P G +  H   ++ +  N    I    + +G + +            S K K +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + + + N+ HIP SPF + V   P+ D
Sbjct: 2041 QSEIGDASR----VRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAP---------------SVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKT--HE-AEIVEGENHTYCIRFVPAEMGTHTV------------SVKYKGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLAIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSVKF-NEEHIPDSPFVVPV-ASPSGD 2331          

HSP 7 Score: 65.855 bits (159), Expect = 5.225e-9
Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV--IGLENKN-----TKSFIIDSRNS 1532
             F   P++ G++ + I        I   PF V V        + ++GPGL G V      F+++  G D   +GFS+EGPS+ KIEC + G+GS  + Y     G Y + ++ N E+I  SP+   I  + +     +VK    GLE           F +D+++ 
Sbjct:  539 GFEYYPMVPGTYIVTITWG--GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHG 702          

HSP 8 Score: 60.8474 bits (146), Expect = 1.557e-7
Identity = 35/132 (26.52%), Postives = 70/132 (53.03%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P  +G  ++ I+ +  +M I   P +  V+  N    + +YGPGL   V + P  F ++T +  +  +  ++EGPSK +I C +  +G+  ++Y  +LPG Y + +  NE+++  SP++  +
Sbjct: 1824 KDGTVTVRYAPSEAGLHEMDIRYD--NMHIPGSPLQFYVDYVNCG-HVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARV 1952          

HSP 9 Score: 56.9954 bits (136), Expect = 2.450e-6
Identity = 58/218 (26.61%), Postives = 94/218 (43.12%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEE-NICDSPYSIVI-----VKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFV 1673
            ++ +   IP  +G + I +K N     I   PF++ V  P     P +VS YG GL G V   P  F+++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI      +I  SP+   +     V ++ + E   V V  L    TK+       +    P D       G+  +   V   +K  F ++C       L+V V
Sbjct: 2386 DKYAVRFIPRENGVYLIDVKFN--GTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL----TKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVG--QKSSFTVDCSKAGNNMLLVGV 2594          
BLAST of Filamin A vs. UniProt/SwissProt
Match: sp|D3ZHA0|FLNC_RAT (Filamin-C OS=Rattus norvegicus OX=10116 GN=Flnc PE=1 SV=1)

HSP 1 Score: 156.762 bits (395), Expect = 1.262e-36
Identity = 131/498 (26.31%), Postives = 229/498 (45.98%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLV-VEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDI---FIKKNEYSMEILNKPFRVCVNL----PNKKPTIVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            +++ EM  T+ ++ +     KI++  FTRW N  LK   K + DLQ DL +G  L+ L+E+LSQK++  K       RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  +        L W+ +K+    I N +  W  G A+G +V+ C   LC D   W+ +  + NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF        + +  ++ N K  +        I+  GNT +  A  +                             + T++  + + LV +E  D  G+  +     N  K    + S +P ++G   +   F  +N     I   PF V V +     NK   + + GPGL   G+VA+ P  F + T G+    +   +  P   +  +E A  + G+ +   TY  ++ G + + +      I  SP+ + + ++
Sbjct:   17 DEADEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAI---AYGPGIEPQGNTVLQPAHFT-----------------------------VQTVDAGVGEVLVYIE--DPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN-----IERSPFEVNVGMALGDANK---VSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEA 472          

HSP 2 Score: 113.62 bits (283), Expect = 1.512e-23
Identity = 102/326 (31.29%), Postives = 147/326 (45.09%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQ-NKGNSTSIKPVGKNLIF--HVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + VA   D  RR+    ++     E  ++ N+  S +++  G   +    V +P      C+V+E    S  H I+ +   +             GV++ID   F G  I G  +K+++                  Q  +P +V+       AYG GL+  T    + F +   N          +L VTIDGPSKVQ+ C E   G++  Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2316 HKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQ-----ETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD--SDKHTIRFIPHEN-------------GVHSIDV-KFNGAHIPGSPFKIRVGE--------------QSQAGDPGLVS-------AYGPGLEGGTTGVSSEFIVNTQNAGSG------ALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKV 2593          

HSP 3 Score: 85.5001 bits (210), Expect = 6.257e-15
Identity = 86/329 (26.14%), Postives = 128/329 (38.91%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNKDG--FINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN    F + T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF   +  D + R                 N G ST +          ++  ++  L   +  P G      +K++       S T  + G   ++V  S   V N  F   +G  +IG + KV++                                   +G GL +    +   F +   N           L ++I+GPSKV I+C +  +G     Y P   G Y I I +++K H+PGSPF + V
Sbjct: 1863 VSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMR-------------TSQLNVGTSTDVS-------LKITEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRV-----------------------------------WGKGLSEGQTFQVAEFIVDTRNAGYG------GLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADK-HVPGSPFTVKV 2129          

HSP 4 Score: 70.0922 bits (170), Expect = 2.816e-10
Identity = 51/165 (30.91%), Postives = 82/165 (49.70%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL----YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRNS 1532
            P++ G + + I    Y+  I   PF V V+       + ++GPGL     G  AD    F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I  +       KVK  G   + T         F ID+R +
Sbjct:  540 PVIPGKYVVTITWGGYA--IPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSAD----FVVEAIGTEVGTLGFSIEGPSQAKIECDDRGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAA 698          

HSP 5 Score: 65.855 bits (159), Expect = 4.861e-9
Identity = 40/133 (30.08%), Postives = 64/133 (48.12%), Query Frame = 3
Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            S +   +   +P   G + + I  + +   +   PF V   LP     + +YGPGL G +   P  F +DT G+        +EGP + KIEC + G+GS  ++Y    PG Y ++I+  E +I  SP+   I
Sbjct: 1020 SGAEAQAVRYMPPEEGPYKVDITYDGHP--VPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATI 1150          

HSP 6 Score: 61.2326 bits (147), Expect = 1.255e-7
Identity = 40/93 (43.01%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L  G VN  N+F V T G   G L + IEGPS+A++S  D K G   V Y    PG+Y   I+F    IP SPFR+ V D V+
Sbjct: 1351 PTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYVPFTPGDYDVNITFGGQPIPGSPFRVPVKDVVD 1443          

HSP 7 Score: 58.151 bits (139), Expect = 1.183e-6
Identity = 40/118 (33.90%), Postives = 57/118 (48.31%), Query Frame = 3
Query: 4881 TESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS 5228
            +E GD S+    V V GK L +G      +F+V T     G L + IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  +   I  +   P I +
Sbjct: 2037 SEIGDASK----VRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIAT 2150          
BLAST of Filamin A vs. TrEMBL
Match: A0A5K3FEG0 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 6.185e-47
Identity = 187/759 (24.64%), Postives = 304/759 (40.05%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGEN---NFDEIGKS----FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE-----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDK------LGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243
            I+K  FTRW N  LK     + D+QFD  +G  L++LIE LS +K   +      R  ++  +  VL FL   EG+ L NI+  DI+D   K I  L+W LI HYSI   L E    N    G +     L+WLNSKL    + N ++ WN G AIG +V+ C   LC D  +W     L NA  AM AA Q   +PQL+ P E+I+    +KA+MTY+SQF          L+ R N     + +     ++  GN   M A  + D  S                G V++++                 ++  G    C    N  + N  S + +P  +G + + IK    + EI+N PF+V V        + + GPG+                       VADC    ILD  G    I      P+ T+    N      L+ Y+  + G++ +++    + I +SP+ +++     +++     +   ++  L++    S I    N ++  PP   C  K       G+    + V +L                       F V  E         ++ EG  +       +  +EKC     Q  +          CV T      +T   +    H      ++    +  K+  +  +G  L G  + K    VV+ + +     G++GF +EGP E ++ C    DG   + + P   G+Y + +  + ++I  SP+ + +   S
Sbjct:   46 IQKNTFTRWANEHLKTKGTSVDDIQFDFADGLRLIDLIESLSGQKFRHVNRKPSFRTQKLENVTMVLRFLEEQEGLRLVNIDSTDIVDCRTKLILGLIWTLILHYSITLPLWEGEDYNQGSTGPTPKQRLLSWLNSKLMERPVKNFTTDWNDGTAIGALVDACAPGLCPDWREWEPKQKLRNATEAMRAAEQWLEVPQLIHPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRAN---PASVRAYGPGLEPKGNKVGMPARFTIDASS-------------AGKGSVEVIV-----------------LNPKGQREPCDIVPNTDRPNTYSCAYVPTQAGEYRVIIKF--ATKEIMNSPFKVMVEGAADPSKVTASGPGIEPQGNQVGRRTFFNIFTAGAGEGVADC---VILDPQGRQDVI-----KPNITRQSEDNY-----LVEYTPRMEGLHSVNVFFAGQQIPNSPFGVMVGPQAPIEQGGSKPLNANRIPALKSDQPISPIKRPDNQSY-APPRPACDAKQAYATGRGIQPQGVRVRDLAD---------------------FKVHTE---------EAGEGVLEATVVGP-TGREEKC----QQRKIGPYTYE----CVYTPQQPGPHTVNVRYGGDHIMLSPFKVDVGPY--KETRIRAFGPGLVGGIVNKPAVFVVETNGET----GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADS 710          

HSP 2 Score: 100.523 bits (249), Expect = 5.326e-17
Identity = 57/156 (36.54%), Postives = 86/156 (55.13%), Query Frame = 3
Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577
             I+  PF+V V  P K+  I ++GPGL G + + P VF+++TNG    +GFS+EGPS+ +I+CA+ G+GS  + Y   +PG Y + I+ NEENI  SPY + I   +   +   VK        G+       F ID+R++    P   E  D+ G
Sbjct:  605 HIMLSPFKVDVG-PYKETRIRAFGPGLVGGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADSGKCDPNAVKCYGPGLSPGVVAGIPTEFTIDARDAGGPAPFACELRDEAG 759          

HSP 3 Score: 95.1301 bits (235), Expect = 2.137e-15
Identity = 43/88 (48.86%), Postives = 61/88 (69.32%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVAD 5177
            +V V+G+ + +G+ N NN+F ++T     GNL+I IEGPSKAEI F D+K G  +VS+RV+ PGEY C+I FN   +  SPFR+ + D
Sbjct: 2095 KVRVLGQGIQRGYANCNNEFSIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCVVSFRVSEPGEYFCSIRFNDEHVQGSPFRLDIED 2182          

HSP 4 Score: 88.5817 bits (218), Expect = 2.089e-13
Identity = 86/337 (25.52%), Postives = 146/337 (43.32%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-SKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870
            ++E G+ S+    V V G+ L +G  N N +F V TS    G L++ IEGPSKA+I   D + G  +V+YR T PG Y+  + +   ++P SPF + +    + R++ +  +    +E          ++K  G N         +  ++  VT P G    H  K M S+  + +  I       GV+ +               V+  N+H  GS    T         + P I +     +   G G+Q+   N  N F I+             +L + I+GPSK +I   +  +G   C +   +   G YF  I ++++ H+ GSPF++ +
Sbjct: 1894 ESELGNASR----VRVYGRGLHEGTANQNCQFTVDTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGHPSARVMERITRQREVAEATQVGSQCELNLKIPGVN---------VREMSAVVTSPSG----HTEKCMVSELDHANYCIRFVPQETGVHTV--------------SVRHRNLHIPGSPFQFT---------VGP-ITDGGANKVRVLGQGIQRGYANCNNEFSIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CVVSFRVSEPGEYFCSIRFNDE-HVQGSPFRLDI 2180          

HSP 5 Score: 85.5001 bits (210), Expect = 1.653e-12
Identity = 87/335 (25.97%), Postives = 135/335 (40.30%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888
            V   G  L  G      +F + T     G L+I +EGPSKAEI   D K G    SY    PGEY  +I F    I  SPF   + +D  R      V     SEV ++                  +S  +I NL   VT P G      IK++       S T  +  D  +NV+ +   + N  F  F+G+ ++G + +V++                                   YG GL + T N+   F +      ++       L ++I+GPSK  I C ++ +G  +  Y P   G Y I + Y+++ ++PGSPF + +   P++
Sbjct: 1722 VTAYGPGLSHGRAGEPAEFTLVTREAGAGGLSIAVEGPSKAEIVCRDNKNGTCSASYLPLAPGEYTISIKFMDQHIQGSPFIANIMEDPLRM---TQVMVGTTSEVPLR------------------ISETDIYNLTATVTNPSGIEQPSMIKRLPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNASRVRV-----------------------------------YGRGLHEGTANQNCQFTV------DTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGHPSA 1993          

HSP 6 Score: 79.7221 bits (195), Expect = 1.070e-10
Identity = 90/344 (26.16%), Postives = 138/344 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICI--EGPSKAEISFMDKKIGIYIVSYRVTIPG-EYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV--------SSPEILNLNCFVTEPHGGSSFHPIKKMSK-TSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSC------DVDIQIINPLIVNEIYQN----ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P  V V G  +     N    F+V      PGN+ I +  E      +   D + G + V+Y     G  Y   + F   ++P SPF++ V  +V+   +H    P               S  PVGK   F V        SSP+    N  V  P+G      ++  S+ T   DG+   F  T+               GP  +V ++     +R +   C      D  I  +         Q+    + AYGDGL++AT N   HF I      +S       L VTI+GP++ QI+  ++ +G     Y+P+  G Y + + Y +K H+PGSPF + V
Sbjct:  812 PGNVRVYGPGVESITRNEPTYFIVDCKQAGPGNVGISVRDEAGRDVPMDTKDMRDGTFKVAYTPMTAGPTYTVQVYFENTEVPRSPFKVPVKPNVDMSKVHVDGLP---------------STIPVGKPTTFDVVTAGAGPPSSPKP-RPNVIVKAPNG------MRVPSQLTETPDGYEATFTPTMP--------------GPH-QVAVDVAGAPVRGSPFPCNAVPIQDAPIAAVKKPATFAAQQDPSGLVHAYGDGLRKATANVPAHFTI------DSREAPPAPLSVTIEGPAEAQINYTDNGDGTCGVDYLPVEPGPYTVNVLYKDK-HVPGSPFPVQV 1111          

HSP 7 Score: 73.9442 bits (180), Expect = 4.942e-9
Identity = 40/93 (43.01%), Postives = 52/93 (55.91%), Query Frame = 3
Query: 5604 AYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882
            A GDGL +  V  ++ FF+   N          SL VT+DGPSKVQ++C E ++GY F Y P   G Y I +TY  + HI  SPF+  V  DP
Sbjct: 2292 ANGDGLNRGVVGERSRFFVNTANAGSG------SLSVTVDGPSKVQLNCNERLDGYEFSYTPYAPGQYNISVTYDGQ-HIHHSPFRAYVTGDP 2377          
BLAST of Filamin A vs. TrEMBL
Match: A0A5K3FF65 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 7.350e-47
Identity = 187/759 (24.64%), Postives = 304/759 (40.05%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGEN---NFDEIGKS----FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE-----IKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDK------LGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243
            I+K  FTRW N  LK     + D+QFD  +G  L++LIE LS +K   +      R  ++  +  VL FL   EG+ L NI+  DI+D   K I  L+W LI HYSI   L E    N    G +     L+WLNSKL    + N ++ WN G AIG +V+ C   LC D  +W     L NA  AM AA Q   +PQL+ P E+I+    +KA+MTY+SQF          L+ R N     + +     ++  GN   M A  + D  S                G V++++                 ++  G    C    N  + N  S + +P  +G + + IK    + EI+N PF+V V        + + GPG+                       VADC    ILD  G    I      P+ T+    N      L+ Y+  + G++ +++    + I +SP+ +++     +++     +   ++  L++    S I    N ++  PP   C  K       G+    + V +L                       F V  E         ++ EG  +       +  +EKC     Q  +          CV T      +T   +    H      ++    +  K+  +  +G  L G  + K    VV+ + +     G++GF +EGP E ++ C    DG   + + P   G+Y + +  + ++I  SP+ + +   S
Sbjct:   46 IQKNTFTRWANEHLKTKGTSVDDIQFDFADGLRLIDLIESLSGQKFRHVNRKPSFRTQKLENVTMVLRFLEEQEGLRLVNIDSTDIVDCRTKLILGLIWTLILHYSITLPLWEGEDYNQGSTGPTPKQRLLSWLNSKLMERPVKNFTTDWNDGTAIGALVDACAPGLCPDWREWEPKQKLRNATEAMRAAEQWLEVPQLIHPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRAN---PASVRAYGPGLEPKGNKVGMPARFTIDASS-------------AGKGSVEVIV-----------------LNPKGQREPCDIVPNTDRPNTYSCAYVPTQAGEYRVIIKF--ATKEIMNSPFKVMVEGAADPSKVTASGPGIEPQGNQVGRRTFFNIFTAGAGEGVADC---VILDPQGRQDVI-----KPNITRQSEDNY-----LVEYTPRMEGLHSVNVFFAGQQIPNSPFGVMVGPQAPIEQGGSKPLNANRIPALKSDQPISPIKRPDNQSY-APPRPACDAKQAYATGRGIQPQGVRVRDLAD---------------------FKVHTE---------EAGEGVLEATVVGP-TGREEKC----QQRKIGPYTYE----CVYTPQQPGPHTVNVRYGGDHIMLSPFKVDVGPY--KETRIRAFGPGLVGGIVNKPAVFVVETNGET----GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADS 710          

HSP 2 Score: 138.272 bits (347), Expect = 1.593e-28
Identity = 103/333 (30.93%), Postives = 158/333 (47.45%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN-LNCFVTEPHGGSS---FHPIK------KMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882
            +V V+G+ + +G+ N NN+F ++T     GNL+I IEGPSKAEI F D+K G  +VS+RV+ PGEY C+I FN   +  SPFR+ + +D       +H +  + +   +Q++G       +G  + F V+   +   L  +V  P G        P+       + +   N    ++V      +    F   +G +      +   N  G  R           +++P       Q+I A G GL    V  ++ FF+   N          SL VT+DGPSKVQ++C E ++GY F Y P   G Y I +TY  + HI  SPF+  V  DP
Sbjct: 2095 KVRVLGQGIQRGYANCNNEFSIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCVVSFRVSEPGEYFCSIRFNDEHVQGSPFRLDI-EDTGGYYASEHRQLSVAA---VQDRGLQ-----IGVPMAFTVNYTGVRGRLRAYVVTPSGKEEPAVVLPVDIDQHAVRFTPQENGPHLVHVLLDDRPIPGSPFRVLVGQEDFCEPGLVRANGDGLNRG----------VVDP-------QSIVASGAGLTSGAVGERSRFFVNTANAGSG------SLSVTVDGPSKVQLNCNERLDGYEFSYTPYAPGQYNISVTYDGQ-HIHHSPFRAYVTGDP 2394          

HSP 3 Score: 100.138 bits (248), Expect = 5.657e-17
Identity = 57/156 (36.54%), Postives = 86/156 (55.13%), Query Frame = 3
Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577
             I+  PF+V V  P K+  I ++GPGL G + + P VF+++TNG    +GFS+EGPS+ +I+CA+ G+GS  + Y   +PG Y + I+ NEENI  SPY + I   +   +   VK        G+       F ID+R++    P   E  D+ G
Sbjct:  605 HIMLSPFKVDVG-PYKETRIRAFGPGLVGGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNEENIPKSPYMVPIQADSGKCDPNAVKCYGPGLSPGVVAGIPTEFTIDARDAGGPAPFACELRDEAG 759          

HSP 4 Score: 88.5817 bits (218), Expect = 2.127e-13
Identity = 86/337 (25.52%), Postives = 146/337 (43.32%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-SKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870
            ++E G+ S+    V V G+ L +G  N N +F V TS    G L++ IEGPSKA+I   D + G  +V+YR T PG Y+  + +   ++P SPF + +    + R++ +  +    +E          ++K  G N         +  ++  VT P G    H  K M S+  + +  I       GV+ +               V+  N+H  GS    T         + P I +     +   G G+Q+   N  N F I+             +L + I+GPSK +I   +  +G   C +   +   G YF  I ++++ H+ GSPF++ +
Sbjct: 1894 ESELGNASR----VRVYGRGLHEGTANQNCQFTVDTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGHPSARVMERITRQREVAEATQVGSQCELNLKIPGVN---------VREMSAVVTSPSG----HTEKCMVSELDHANYCIRFVPQETGVHTV--------------SVRHRNLHIPGSPFQFT---------VGP-ITDGGANKVRVLGQGIQRGYANCNNEFSIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CVVSFRVSEPGEYFCSIRFNDE-HVQGSPFRLDI 2180          

HSP 5 Score: 85.5001 bits (210), Expect = 1.697e-12
Identity = 87/335 (25.97%), Postives = 135/335 (40.30%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888
            V   G  L  G      +F + T     G L+I +EGPSKAEI   D K G    SY    PGEY  +I F    I  SPF   + +D  R      V     SEV ++                  +S  +I NL   VT P G      IK++       S T  +  D  +NV+ +   + N  F  F+G+ ++G + +V++                                   YG GL + T N+   F +      ++       L ++I+GPSK  I C ++ +G  +  Y P   G Y I + Y+++ ++PGSPF + +   P++
Sbjct: 1722 VTAYGPGLSHGRAGEPAEFTLVTREAGAGGLSIAVEGPSKAEIVCRDNKNGTCSASYLPLAPGEYTISIKFMDQHIQGSPFIANIMEDPLRM---TQVMVGTTSEVPLR------------------ISETDIYNLTATVTNPSGIEQPSMIKRLPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNASRVRV-----------------------------------YGRGLHEGTANQNCQFTV------DTSDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGHPSA 1993          

HSP 6 Score: 79.7221 bits (195), Expect = 1.089e-10
Identity = 90/344 (26.16%), Postives = 138/344 (40.12%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICI--EGPSKAEISFMDKKIGIYIVSYRVTIPG-EYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV--------SSPEILNLNCFVTEPHGGSSFHPIKKMSK-TSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSC------DVDIQIINPLIVNEIYQN----ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P  V V G  +     N    F+V      PGN+ I +  E      +   D + G + V+Y     G  Y   + F   ++P SPF++ V  +V+   +H    P               S  PVGK   F V        SSP+    N  V  P+G      ++  S+ T   DG+   F  T+               GP  +V ++     +R +   C      D  I  +         Q+    + AYGDGL++AT N   HF I      +S       L VTI+GP++ QI+  ++ +G     Y+P+  G Y + + Y +K H+PGSPF + V
Sbjct:  812 PGNVRVYGPGVESITRNEPTYFIVDCKQAGPGNVGISVRDEAGRDVPMDTKDMRDGTFKVAYTPMTAGPTYTVQVYFENTEVPRSPFKVPVKPNVDMSKVHVDGLP---------------STIPVGKPTTFDVVTAGAGPPSSPKP-RPNVIVKAPNG------MRVPSQLTETPDGYEATFTPTMP--------------GPH-QVAVDVAGAPVRGSPFPCNAVPIQDAPIAAVKKPATFAAQQDPSGLVHAYGDGLRKATANVPAHFTI------DSREAPPAPLSVTIEGPAEAQINYTDNGDGTCGVDYLPVEPGPYTVNVLYKDK-HVPGSPFPVQV 1111          
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3P3Q8 (Filamin-A OS=Schistocephalus solidus OX=70667 GN=FLNA PE=4 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.783e-46
Identity = 203/771 (26.33%), Postives = 313/771 (40.60%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVK-----------SNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNA---ERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDV---LVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTG 2252
            I+K  FTRW N  LK  +  + DLQFDL +G  L+EL+E LS +K    R  N+    R   L +V + LR     EG+ L NI+  DI+D  +K I  L+W LI HYSI   L E   D  G       +  L WLNSKL    + N ++ WN G AIG +V++C   LC D   W     L NAQ AM AA Q   +PQL++P E+I+    +KA+MTY+SQF          L+ R N     + +     ++  GN   M A  + D  S                G V++++                 ++  G    C    N  + N  S + +P  SG + + IK    + EI+N PF+V V          + GPG+                       VADC    ILD  G    I      P  T+    N      L+ Y+  + G++ +++    + I +SP+ +++             +NK  E  K  +     +  K +      +   +PP         VS      ++  +  ++  C    A    R I   G  +  +  F   +   D+ EG  +       +  +EKC     Q  V A        CV T       LVN R     I    F   +++   + D +  +  +G  L    + K    VV+ + +    G SI    EGP E ++ C    DG   + + P   G+Y + +  + ++I  SP+ + +S  +DTG
Sbjct:   40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI-----KPVITRQSEDNY-----LVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMVGPRIQDAPPLTPLANKPIEATKTPIQQAGPRAAKPW------NAQPVPPSEPL-----VSPRAAPRSDQMRAPWKTACDPKQAYATGRGIQPQGVRVRDLADF--KVHTEDAGEGVLEATVVGP-NGREEKC----QQRKVGAYLHE----CVYTPQQPGPHLVNVRYGGDHIMLSPF---KVEVGPYKDTR--IRAFGPGLVSGIVNKPAVFVVETNGETGALGFSI----EGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPIS--ADTG 726          

HSP 2 Score: 98.5969 bits (244), Expect = 1.964e-16
Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3
Query:  954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577
            +  + A   V+EA  V  NG   KC +    +  +E  ++  P   G   + ++       I+  PF+V V  P K   I ++GPGL   + + P VF+++TNG    +GFS+EGPS+ +I+CA+ G+GS  + Y   +PG Y + I+ N+ENI  SPY + I       +  +VK        G+       F +D+R +    P  V+  D +G
Sbjct:  564 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 774          

HSP 3 Score: 95.5153 bits (236), Expect = 1.663e-15
Identity = 47/112 (41.96%), Postives = 69/112 (61.61%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQN 5246
            ++V  +G  L  G++  NN+F ++T     GNL+I IEGPSKAEI F D+K G   VS+RVT PGEY+C+I FN   +P SPFR+ + D  + ++     K    + V+ +N
Sbjct: 2112 HKVRAMGPGLQHGYIYANNEFNIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCCVSFRVTEPGEYLCSIRFNDEHVPGSPFRVDIEDTGSNQVYATETKQLSVAAVQDRN 2223          

HSP 4 Score: 88.5817 bits (218), Expect = 1.798e-13
Identity = 84/326 (25.77%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN---LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870
            V V G+ L +G  N N +F V T     G L++ IEGPSKA+I   D + G  +V+YR T PG Y+  + +   ++P SPF + +    +  ++ +  +    +E          S+K  G N   L   V+SP      C ++EP             + SN    I      +GV+ +               ++  NIH  GS    T         + P I +     + A G GLQ   +   N F I+             +L + I+GPSK +I   +  +G   C +   +   G Y   I ++++ H+PGSPF++ +
Sbjct: 1921 VRVYGRGLREGMANQNCQFTVDTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGQPSPLVMERITRQREVAEATHVGSQCELSLKIPGVNPRELTAVVTSPSGRTEQCVISEP-------------EPSNYS--IRFVPQELGVHTV--------------SIRHRNIHVPGSPFQFT---------VGP-ITDGGAHKVRAMGPGLQHGYIYANNEFNIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CCVSFRVTEPGEYLCSIRFNDE-HVPGSPFRVDI 2198          

HSP 5 Score: 85.8853 bits (211), Expect = 1.182e-12
Identity = 87/334 (26.05%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPN 5885
            V   G  L  G      +F + T     G L+I +EGPSK+EI   D K G    SY    PGEY  AI F    I  SPF   + +D  R      V     SEV ++                  +S  +I NL   VT P G      IK+M       S T  +  D  +NV+ +   + N  F  F+G+ ++G + +V++                                   YG GL++   N+   F +      ++       L ++I+GPSK  I C ++ +G  +  Y P   G Y I + Y+++ ++PGSPF + +   P+
Sbjct: 1740 VTAYGPGLSHGRTGEPAEFTLVTRDAGAGGLSIAVEGPSKSEIICRDNKNGTCSASYLPLAPGEYTIAIKFMDQHIQGSPFLARIVEDPRRM---TQVVVGTTSEVPLR------------------ISETDIYNLTASVTSPSGVEQPSVIKRMPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNAARVRV-----------------------------------YGRGLREGMANQNCQFTV------DTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGQPS 2010          

HSP 6 Score: 73.9442 bits (180), Expect = 5.756e-9
Identity = 42/95 (44.21%), Postives = 55/95 (57.89%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882
            + A GDGL +  V  KN FF+   N S++      +L VT+DGPSKVQ++C E  +GY F Y P   G Y I I Y ++ HI  SPF+  V  DP
Sbjct: 2309 VFASGDGLSRGVVGEKNRFFV---NTSQA---GSGALSVTVDGPSKVQLNCSERPDGYEFTYTPYAPGNYTISIKYEDQ-HIVQSPFRAFVTGDP 2396          
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3NX60 (Filamin-A (Fragment) OS=Schistocephalus solidus OX=70667 GN=FLNA PE=4 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.826e-44
Identity = 142/482 (29.46%), Postives = 209/482 (43.36%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            I+K  FTRW N  LK  +  + DLQFDL +G  L+EL+E LS +K    R  N+    R   L +V + LR     EG+ L NI+  DI+D  +K I  L+W LI HYSI   L E   D  G       +  L WLNSKL    + N ++ WN G AIG +V++C   LC D   W     L NAQ AM AA Q   +PQL++P E+I+    +KA+MTY+SQF          L+ R N     + +     ++  GN   M A  + D  S                G V++++                 ++  G    C    N  + N  S + +P  SG + + IK    + EI+N PF+V V          + GPG+                       VADC    ILD  G    I          K         + L+ Y+  + G++ +++    + I +SP+ +++
Sbjct:   40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI----------KPVITRQSEDNYLVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMV 470          

HSP 2 Score: 98.5969 bits (244), Expect = 1.874e-16
Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3
Query:  954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577
            +  + A   V+EA  V  NG   KC +    +  +E  ++  P   G   + ++       I+  PF+V V  P K   I ++GPGL   + + P VF+++TNG    +GFS+EGPS+ +I+CA+ G+GS  + Y   +PG Y + I+ N+ENI  SPY + I       +  +VK        G+       F +D+R +    P  V+  D +G
Sbjct:  581 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 791          

HSP 3 Score: 63.1586 bits (152), Expect = 9.014e-6
Identity = 37/97 (38.14%), Postives = 49/97 (50.52%), Query Frame = 3
Query: 4908 PYE---VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNR 5189
            PY+   +   G  L  G VN    FVV T+G+  G L   IEGPS+A I   D   G   V Y  T+PGEY   I  N  +IP SP+ + ++ D  +
Sbjct:  649 PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGET-GALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGK 744          
BLAST of Filamin A vs. TrEMBL
Match: A0A0X3PDR0 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR102074 PE=4 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 4.407e-44
Identity = 144/482 (29.88%), Postives = 211/482 (43.78%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRL----EGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG-------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYG--------------------SVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            I+K  FTRW N  LK  +  + DLQFDL +G  L+EL+E LS +K    R  N+    R   L +V + LR     EG+ L NI+  DI+D  +K I  L+W LI HYSI   L E   D  G       +  L WLNSKL    + N ++ WN G AIG +V++C   LC D   W     L NAQ AM AA Q   +PQL++P E+I+    +KA+MTY+SQF          L+ R N     + +     ++  GN   M A  + D  S                G V++++                 ++  G    C    N  + N  S + +P  SG + + IK    + EI+N PF+V V          + GPG+                       VADC    ILD  G    I      P  T+    N      L+ Y+  + G++ +++    + I +SP+ +++
Sbjct:   40 IQKNTFTRWANEHLKDKHTSVDDLQFDLADGLRLIELVESLSGQKF---RHVNKKPSFRTQKLENVTMTLRFLEESEGLRLVNIDSTDIVDCRLKLILGLIWTLILHYSITLPLWEGEEDNQGGQGPTPKQRLLAWLNSKLADRPVKNFTTDWNDGTAIGALVDSCAPGLCPDWRDWEPKQKLRNAQEAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKDGAPLRPRTNA---ASVRAYGPGLEPRGNKVGMPARFTIDAFS-------------AGRGAVEVIV-----------------LNPKGQREPCDVIPNTDRQNTYSCAYVPSQSGEYRVIIKF--AAKEIMNSPFKVMVEGAADPSKATASGPGIEPRGNQVGKRTFFNIFTTGAGEGVADC---VILDPQGRQDVI-----KPVITRQSEDNY-----LVEYTPKVEGLHSVNVFFAGQQIPNSPFGVMV 470          

HSP 2 Score: 98.5969 bits (244), Expect = 1.839e-16
Identity = 66/216 (30.56%), Postives = 107/216 (49.54%), Query Frame = 3
Query:  954 IEKDIAKNLVVEA--VDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVI------GLENKNTKSFIIDSRNSTFEMPPDVECFDKLG 1577
            +  + A   V+EA  V  NG   KC +    +  +E  ++  P   G   + ++       I+  PF+V V  P K   I ++GPGL   + + P VF+++TNG    +GFS+EGPS+ +I+CA+ G+GS  + Y   +PG Y + I+ N+ENI  SPY + I       +  +VK        G+       F +D+R +    P  V+  D +G
Sbjct:  581 VHTEDAGEGVLEATVVGPNGREEKCQQRKVGAYLHECVYT--PQQPGPHLVNVRYG--GDHIMLSPFKVEVG-PYKDTRIRAFGPGLVSGIVNKPAVFVVETNGETGALGFSIEGPSEARIDCADNGDGSATVVYWPTVPGEYAVHILCNDENIPKSPYMVPISADTGKCDPNRVKCYGPGISPGVVAGVPTEFTVDAREAGAPAPTTVDVRDDVG 791          

HSP 3 Score: 95.5153 bits (236), Expect = 1.557e-15
Identity = 47/112 (41.96%), Postives = 69/112 (61.61%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQN 5246
            ++V  +G  L  G++  NN+F ++T     GNL+I IEGPSKAEI F D+K G   VS+RVT PGEY+C+I FN   +P SPFR+ + D  + ++     K    + V+ +N
Sbjct: 2129 HKVRAMGPGLQHGYIYANNEFNIYTREAGAGNLSIAIEGPSKAEIDFEDRKDGSCCVSFRVTEPGEYLCSIRFNDEHVPGSPFRVDIEDTGSNQVYATETKQLSVAAVQDRN 2240          

HSP 4 Score: 88.9669 bits (219), Expect = 1.698e-13
Identity = 84/326 (25.77%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN---LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870
            V V G+ L +G  N N +F V T     G L++ IEGPSKA+I   D + G  +V+YR T PG Y+  + +   ++P SPF + +    +  ++ +  +    +E          S+K  G N   L   V+SP      C ++EP             + SN    I      +GV+ +               ++  NIH  GS    T         + P I +     + A G GLQ   +   N F I+             +L + I+GPSK +I   +  +G   C +   +   G Y   I ++++ H+PGSPF++ +
Sbjct: 1938 VRVYGRGLREGMANQNCQFTVDTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADENVPGSPFAVNIGGQPSPLVMERITRQREVAEATHVGSQCELSLKIPGVNPRELTAVVTSPSGRTEQCVISEP-------------EPSNYS--IRFVPQELGVHTV--------------SIRHRNIHVPGSPFQFT---------VGP-ITDGGAHKVRAMGPGLQHGYIYANNEFNIYTREAGAG------NLSIAIEGPSKAEIDFEDRKDGS--CCVSFRVTEPGEYLCSIRFNDE-HVPGSPFRVDI 2215          

HSP 5 Score: 86.2705 bits (212), Expect = 1.126e-12
Identity = 87/334 (26.05%), Postives = 134/334 (40.12%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNK--DGFINVFASTIGVYNIDFYNFLGD-KIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPN 5885
            V   G  L  G      +F + T     G L+I +EGPSK+EI   D K G    SY    PGEY  AI F    I  SPF   + +D  R      V     SEV ++                  +S  +I NL   VT P G      IK+M       S T  +  D  +NV+ +   + N  F  F+G+ ++G + +V++                                   YG GL++   N+   F +      ++       L ++I+GPSK  I C ++ +G  +  Y P   G Y I + Y+++ ++PGSPF + +   P+
Sbjct: 1757 VTAYGPGLSHGRTGEPAEFTLVTRDAGAGGLSIAVEGPSKSEIICRDNKNGTCSASYLPLAPGEYTIAIKFMDQHIQGSPFLARIVEDPRRM---TQVVVGTTSEVPLR------------------ISETDIYNLTASVTSPSGVEQPSVIKRMPNGHLGISFTPREIGDHLVNVYRNGRPIPNSPFKIFVGESELGNAARVRV-----------------------------------YGRGLREGMANQNCQFTV------DTRDAGFGGLSLSIEGPSKADIECHDNQDGTCLVTYRPTEPGTYIINVKYADE-NVPGSPFAVNIGGQPS 2027          

HSP 6 Score: 73.9442 bits (180), Expect = 5.618e-9
Identity = 42/95 (44.21%), Postives = 55/95 (57.89%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDP 5882
            + A GDGL +  V  KN FF+   N S++      +L VT+DGPSKVQ++C E  +GY F Y P   G Y I I Y ++ HI  SPF+  V  DP
Sbjct: 2326 VFASGDGLSRGVVGEKNRFFV---NTSQA---GSGALSVTVDGPSKVQLNCSERPDGYEFTYTPYAPGNYTISIKYEDQ-HIVQSPFRAFVTGDP 2413          
BLAST of Filamin A vs. Ensembl Cavefish
Match: flnb (filamin B, beta (actin binding protein 278) [Source:ZFIN;Acc:ZDB-GENE-041026-1])

HSP 1 Score: 181.8 bits (460), Expect = 3.101e-45
Identity = 136/480 (28.33%), Postives = 225/480 (46.88%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKL-EKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNF-DEIGK-----SFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKI--PTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514
            KI+K  FTRW N  L+  +K I DL+FDL +G  L+ L+E+LS K++  K       RQ ++  ++  L FL  E ++L +I    I+DG++K I  L+W LI HYSI   + E++  D + K       L W+ SK+    I+N S  W  G A+G +V+     LC D   W++   + N + AM+ A     +PQ++ P EI+D    ++++MTY+S F     +        T K  +      G  +  L  +    ++D+ +       D  K G  +L + I  P  E  + +   +E +                     SF  +P   G + + I    ++ + + KPF+V V        I ++GPGL G        F+++  G++    F++EGPS+ KIEC +  +GS  + +     G Y + +M ++E I DSP+   +    +     KVKV G     TK  +
Sbjct:   23 KIQKNTFTRWCNEHLRCMDKQINDLRFDLSDGLNLICLLEVLSHKRMFRKYHARPTLRQLKLDNVSVALEFLDHEKIKLVSISKA-IVDGNLKLILGLVWTLILHYSISIPVWEDDASDTVTKLTPEMRLLGWIQSKVPELPINNFSQDWQDGKALGALVDGL-APLCPDWESWDTVQRVTNTREAMQQADDWLGVPQVIAPEEILDPGVDEQSVMTYLSLFPKARLKPGAPLKPKTPKPKACRATGRGLQARGLRVV---QVADFKV-------DTHKAGPGNLAVHIIGPGNEVAVKQREALEGIS--------------------SFEYMPGDEGDYTVDIT---WANQHIPKPFKVHVGPKAGPQKIRAWGPGLEGGTVGMAASFLVEATGAES---FAIEGPSQAKIECDDQNDGSCFVRFWPSEAGEYAVHVMCDDEEIEDSPFMACVAPKKRGFRPAKVKVYGPGVSPTKVLV 464          

HSP 2 Score: 70.8626 bits (172), Expect = 1.506e-11
Identity = 90/346 (26.01%), Postives = 140/346 (40.46%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY--NFLGDKIGPSW---------------KVKIE-------NIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P ++   G  L  G V     F+V  +G      +  IEGPS+A+I   D+  G   V +  +  GEY   +  +  +I  SPF   VA         +  +P   ++V++   G S +   V     F V +          T+   G     I+ +  +  K   ++V     G+YN  +         I  SW               KVKIE         HGS R  +     DI +++PL +      + AYG GLQ   + ++  F I      ++       L V I+GP +V + C+++ +G  +  Y+PI  G Y I I + N  HIPGSPF   V
Sbjct:  355 PQKIRAWGPGLEGGTVGMAASFLVEATGA----ESFAIEGPSQAKIECDDQNDGSCFVRFWPSEAGEYAVHVMCDDEEIEDSPFMACVAPK------KRGFRP---AKVKVYGPGVSPTKVLVNHKTEFTVDA----------TQAGEGLLRICIQTVDGSCVK---VDVICEEDGIYNCSYTPTAICKHTIVVSWGGVSVPGSPFTVKPGKVKIEPCSARRRRPHGSGRFCS-----DINVVSPLDIPTDAAKVKAYGPGLQGVLLGQQAEFTI------DTREAGSGRLTVIIEGPCRVTLHCVDNEDGTCVVFYLPIEHGEYLIRIYFDNS-HIPGSPFHPVV 662          

HSP 3 Score: 58.9214 bits (141), Expect = 6.466e-8
Identity = 83/308 (26.95%), Postives = 120/308 (38.96%), Query Frame = 3
Query: 4968 KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP------IKKMSKTSNKDGFINVF--ASTIGVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFK 5861
            +F + T     G L + IEGP +  +  +D + G  +V Y     GEY+  I F+   IP SPF   V              P   S+V +   G +      GK     V  P ++N++C V    G  S         I +     N+DG   V     T GVY +   Y        P+  V    ++ S    T  C+V    +N    N     + A G GL Q      N  +I              +L + ++GPS+ ++SC E+ +G Y   Y P V G Y + ITY  K  IPG   K
Sbjct:  595 EFTIDTREAGSGRLTVIIEGPCRVTLHCVDNEDGTCVVFYLPIEHGEYLIRIYFDNSHIPGSPFHPVVQ------------LPLDPSKVVVSGAGLTE-----GK-----VGEPCVVNIDC-VMAGSGDLSVQAVSDKGVIAETKVLENEDGSYTVVYVPLTAGVYTLLLKYGGKVVPNVPAAVVVDPEVYKSHVKFTGQCNVSGDPVNAE-GNHDPSKVLADGLGLFQGLTGHPNKVYI-------------NTLGIMVEGPSESKVSCKENKDGSYTMEYTPSVAGSYDVNITYGGK-SIPGQGMK 864          
BLAST of Filamin A vs. Ensembl Cavefish
Match: FLNB (filamin B [Source:NCBI gene;Acc:103028460])

HSP 1 Score: 170.629 bits (431), Expect = 9.621e-42
Identity = 194/796 (24.37%), Postives = 329/796 (41.33%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD--RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGP--SKTKIEC--ANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKK----VKVIGLENKNTKSFIIDSRNS-------TFEMPPDVECFDKLGVSSNNILVTE-------------------LEKKYFRIEC-PLNNAERLIVF-----------------------VGYFMVQVEGFPYA-IDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTS---LSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243
            KI++  FTRW N  LK  NK I DLQ DL +G  L+ L+EILSQKK+ + +F  +   RQ ++  ++  L FL  E + L +I+   I+DG++K I  ++W LI HYSI   + E   D+  K        L W+  K+    I N S  W  G A+G +V++C   LC D   W++   + NA  AM+ A     IPQ++ P EIID S  ++++MTY+SQF        + L  + N  K    G  +  V    GN  M  A  + D  S                G+V + I+ P   ++      V+AV   G                 S + IP + G   + +       +I   PF V V+      + + + GPGL   G++A+ P  F + T G+   ++   ++ P  +K  +E    + G+     TY  +  G + ++I      I  SPY++ +  ++     +     ++  G+  +    F +D+R++       T + P  +E   KL  + +     E                   + K  F +   P   A+++  +                       VG     +EG   A I+  D N+G   V  + T                 +  E +V  +C D   D+  +     ++   ++ + SQ+K +    +K G I+   +   +  +   KG  +++  + D              PIE +++   K D  Y   + P +A K+ + VT  G S+  SPF + V + S
Sbjct:   16 KIQQNTFTRWCNEHLKCVNKRIADLQLDLSDGLRLIALLEILSQKKMYR-KFHQRPTFRQMKLENVSVALEFLDRENIRLVSIDSKAIVDGNLKLILGMVWTLILHYSISMPVWEGEEDDEAKKATPKQRLLGWIQHKVPDLPITNFSQDWKDGKALGALVDSCAPGLCPDWETWDTEKPVENATEAMQLADDWLGIPQVIAPEEIIDPSVDEQSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGPGIEPV----GNRVMRPAVFTVDTFS-------------AGQGQVTVYIEDPEGRRE-----EVKAVPNEGK-------------KTFSVAYIPQVMGPHKVTVLFA--GQQIPKSPFEVNVDKAQGDASKVTAKGPGLEPLGNIANKPTYFDIYTAGAGVGEVTAVIKDPQGNKNTVEALMEDKGDSVFRCTYRPVQAGPHSVNITFGGIAIPKSPYTVTVGPASSPGACRATGRGLQPRGVRVRQVADFRVDTRSAGSGELKVTVKGPKGLEEPVKLTEAMDGTYAYEYYPNTQGKYTVTITWGGQHIPKSPFEVVVGPEAGAQKIRAWGPGLEGGIVGRSADFVAESIGSDVGVLGFAIEGPSQARIECEDQNDGSCDVKYWPT-----------------EPGEYAVHVMCDD--EDIEDSPFMAYIVPDDKSSDPSQVKAYGPGLEKSGCIINKPAEFTVEAKNAGKGPLKIIAQNADGE------------PIEVKMR--NKGDNVYSCTYTPTSALKHTVAVTWGGVSVPNSPFRVNVGKGS 740          

HSP 2 Score: 77.7962 bits (190), Expect = 1.298e-13
Identity = 78/306 (25.49%), Postives = 124/306 (40.52%), Query Frame = 3
Query: 4971 FVVHTSGKIPGNLAICIEGPSKAEIS--FMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            FVV+T G   G ++  +  P   E+    ++ + G + + Y    PG YV  + F   +IP SPF++ V D     +                N  N T  +P    + F     EI      V  P G ++   I       NKDG + V                  K  P+ +  +  +H     + +  +  +Q     + N    N+ AYG GL     N+   F I+  + +E        LD+ I+GPSK +I+CI++ +G     Y+P + G Y I + Y+ K HI GSPF   +  D
Sbjct: 1635 FVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIPKSPFKVMVTDGAYIPV----------------NSMNGTGFRPFDMVIPFAFRKGEITGE---VHMPSGKTTQPEI-----IDNKDGTVMV------------------KYAPT-EAGLHEMHIKYNGSHIP-ESPLQF---YVNNANSPNVTAYGPGLVYGVANKPATFTIYTEDAAEG------GLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEK-HIAGSPFTARITED 1886          

HSP 3 Score: 76.6406 bits (187), Expect = 3.413e-13
Identity = 91/343 (26.53%), Postives = 147/343 (42.86%), Query Frame = 3
Query: 4875 VKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI--LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQN-ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            V++E GD  +    V V G+ L +G     + FVV T     G LA+ IEGPSK +I   D   G   VSY  T PG Y+ +I F +  +P SPF + V  +   R               +  +  + S+  VG     ++  PEI  L+++  VT P G  S  P  ++ +  N    +      +GV+ ++             K + +++ GS    T         + PL   E   N + A G GL++A +     F I  W            L + ++GPS+ +IS  +  +G     Y+    G Y + + + N+ HIP SP+ + V+  P+ D
Sbjct: 1970 VQSEIGDAGR----VQVFGQGLVEGRTFEMSDFVVDTRDAGYGGLALSIEGPSKVDIQTEDMDDGTCGVSYCPTEPGTYIVSIRFAEDHVPGSPFSVKVTGEGRIR-------------ESISRRQKAASVASVGSVCDLNLKIPEIDALDMSAQVTSPSG--SVEP-AEIVEVGNHTYCVRFVPHEMGVHTVNV------------KYRGQHVPGSPFQFT---------VGPL--GEGGANKVKAGGPGLERAEIGVPAEFSI--WTREAG----AGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKF-NEEHIPESPYLVPVMA-PSDD 2261          

HSP 4 Score: 72.4034 bits (176), Expect = 6.359e-12
Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
            K   +     P  +G  ++ IK N     I   P +  VN  N  P + +YGPGL   VA+ P  F + T + ++  +  ++EGPSK +I C +  +G+  +TY   LPG Y + +  NE++I  SP++  I + NK
Sbjct: 1755 KDGTVMVKYAPTEAGLHEMHIKYN--GSHIPESPLQFYVNNANS-PNVTAYGPGLVYGVANKPATFTIYTEDAAEGGLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDNK 1888          

HSP 5 Score: 66.2402 bits (160), Expect = 4.006e-10
Identity = 35/92 (38.04%), Postives = 48/92 (52.17%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G  N    F ++T     G L + IEGPSKAEI+ +D K G   V+Y  T+PG+Y   + +N+  I  SPF   + +D  RR
Sbjct: 1799 VTAYGPGLVYGVANKPATFTIYTEDAAEGGLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDNKRR 1890          

HSP 6 Score: 63.5438 bits (153), Expect = 2.745e-9
Identity = 35/90 (38.89%), Postives = 50/90 (55.56%), Query Frame = 3
Query: 4929 GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNR 5189
            G  L +  +    +F + T     G L+I +EGPS+AEISF D+K G   VSY    PG+Y  ++ FN+  IP SP+ + V   +DD  R
Sbjct: 2175 GPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLVPVMAPSDDARR 2264          

HSP 7 Score: 63.1586 bits (152), Expect = 4.143e-9
Identity = 35/92 (38.04%), Postives = 47/92 (51.09%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVL 5873
            + AYG GL++ T   +  F I       +      SL VTI+GPSKV++ C E   G+   Y P+  G Y I I Y    HI GSPF+  V+
Sbjct: 2362 VTAYGSGLERGTTGNQADFII------NTTKAGPGSLAVTIEGPSKVKMECQECSEGFKVQYTPMAPGNYLISIKYGGPNHINGSPFRAKVM 2447          

HSP 8 Score: 61.2326 bits (147), Expect = 1.401e-8
Identity = 42/138 (30.43%), Postives = 68/138 (49.28%), Query Frame = 3
Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNE--YSMEIL-------NKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
             KS   +    P    S   +I K E  Y++EIL         PF V   LP     + ++GPGL G +   P  F +DT G+        +EGP++ KIEC++ G+G+  ++Y    PG Y ++I+  + ++  SP+
Sbjct:  986 GKSVPCAVEPQPGKGASLVKYIPKEEGVYTVEILYEGNPVPGSPFPVDAMLPPDPSKVKAFGPGLKGGLVGNPAEFTIDTKGAGTGGLGLTVEGPTEAKIECSDNGDGTCSVSYLPTEPGEYLVNILFEDVHVPGSPF 1123          

HSP 9 Score: 60.4622 bits (145), Expect = 2.631e-8
Identity = 92/415 (22.17%), Postives = 169/415 (40.72%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIV---IVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDY-YDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQ-DLCVDTIN------DVLVNTRTKKLIIKHETFEESQLKTFK--WIDKKFG----LILYG------TSLSGRPIKKGE---CQVVQIDLDRSIQ-GGSIGFVL--EGPIETQVQCFA--------------KDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETS 2243
            +   PF+V V        +V+ GPGL   + D    F + T G+    +G ++EGPS++K+ C +  +GS  + Y+   PG+Y ++I    ++I  SP+ +    +V ++KV         G+  K  +SF +D             C  K GV+   + VT  +     ++  ++N +        +   VEG PY++   Y   E  R   +     +     +      L   +  S+  +  +D  +       V +  +  KL  K     ++Q  T+K  ++  K G    +I YG      +    R    G+   C V    +  +I  G  +GFV+  +G  + +V C                 +DG + I +     G Y ++V   G++I  SPF + V++ +
Sbjct: 1313 VPKSPFQVGVGEGCDPARVVAKGPGLEEGLTDKANKFSIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGVGSGVRAKIPQSFTVD-------------C-SKAGVAPLAVAVTGPKGVAEPVDV-IDNGDGTHTVA--YTPSVEG-PYSVVVKYADEEVPRSPFKLRVLPTHDASKVRASGPGLTTGLPASLPVEFTIDAKDAGEGQLSVQITDQDGKL--KTANISDNQDGTYKVSYVPDKVGRYTIVIKYGGDEIPTSPYRVRATTSGDASKCTVTGPGIGPTIGIGEEVGFVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIPKSPFKVMVTDGA 1707          

HSP 10 Score: 58.5362 bits (140), Expect = 1.026e-7
Identity = 76/335 (22.69%), Postives = 129/335 (38.51%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI--CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSI------KPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPS---LDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P +V   G  L +G V   +   V  +   PG L +    +  SKA+   +D K G Y V+Y     G Y   + +    +P+ P ++ V   V+   + K   P +  E   +      ++      K  GK++   V +P     +C + +   G+      K+  T  ++G   + V      V    F   +G+   P+                                     + A G GL++   ++ N F         SII +      L +T++GPS+ ++SC ++ +G     Y P   GLY + ITY  + HI GSPFK+ V
Sbjct: 1133 PTKVVASGSGLKRGKVGEISVVNVDCAKAGPGQLTLEAMSDAGSKAKTEVLDNKDGTYTVTYVPLTAGMYTLLLKYGGQAVPNFPAKVVVDPAVDTSKV-KVFGPGVAGEGLFREATTDFTVDARALTKVGGKHIKAQVKNPSGAATDCVIADQGDGTY-----KVEYTPFENGVHAVEVLYDDTPVPKSPFQVGVGEGCDPA------------------------------------RVVAKGPGLEEGLTDKANKF---------SIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQ-HIQGSPFKVPV 1415          

HSP 11 Score: 56.225 bits (134), Expect = 5.464e-7
Identity = 43/149 (28.86%), Postives = 66/149 (44.30%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHG 5351
            P  V   G  L +G  +  NKF + T G   G L I +EGPS++++S  D K G   V Y    PG Y   I++    I  SPF++ V D V+             S+V++   G  + ++  + ++     S   +  L   VT P G
Sbjct: 1328 PARVVAKGPGLEEGLTDKANKFSIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVD------------ASKVKLSGPGVGSGVRAKIPQSFTVDCSKAGVAPLAVAVTGPKG 1464          

HSP 12 Score: 53.5286 bits (127), Expect = 3.558e-6
Identity = 28/103 (27.18%), Postives = 46/103 (44.66%), Query Frame = 3
Query: 2061 GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSS 2369
            G +G  +EGP E+++ C    DG   +++ P   G Y++ +T  G+ I GSPF + V +  D        P   S     + Q  + +  K G  P    V+ 
Sbjct: 1359 GGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGVGSGVRAKIPQSFTVDCSKAGVAPLAVAVTG 1461          

HSP 13 Score: 51.9878 bits (123), Expect = 9.117e-6
Identity = 47/188 (25.00%), Postives = 86/188 (45.74%), Query Frame = 3
Query: 1197 GPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK-----SFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIE-CPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEG 1739
            GPGL  +    P  F I         +  ++EGPS+ +I   +  +GS  ++Y A  PG Y++S+  NEE+I +SPY + ++  +  D+ +++ V  L+    K     SF +    +   +  D +     G +    +V+ELE+  + I   P  N    I  V +    + G P+ +   +  +G
Sbjct: 2175 GPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLVPVMAPS--DDARRLTVTSLQESGLKVNQPTSFAVRLNGAQGAI--DAKVHSPSG-ALEECVVSELEQDKYAIRFIPRENGIHTI-DVKFNGTHIPGSPFEVRVGEPGQG 2356          
BLAST of Filamin A vs. Ensembl Cavefish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145])

HSP 1 Score: 166.777 bits (421), Expect = 1.422e-40
Identity = 145/526 (27.57%), Postives = 242/526 (46.01%), Query Frame = 3
Query:   51 NKSQEMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD---RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDE-------IGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF-------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGL--YGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTK--IECA--NIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK----VDEIKKVKVIGLENKNTKSFIIDSRNS 1532
            +K  +M  T+ ++ +     KI++  FTRW N  LK  NK I +LQ DL +G  L+ L+E+LSQKK+   R  NQ    RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + +   D          +  L W+ +KL    I N S  W SG A+G +V++C   LC D   W+ +  ++NA+ AM+ A +   +PQ++ P EI+D +  + ++MTY+SQF          L+ + N K     +     I+  GN  M  A  + + IS                G V + ++ P   ++ AK                    N  K+   S   IP ++G   + +      + I   PF V V +     + + + GPGL   G++A+    F + T G+   ++   +  PS  K  +EC   + GN S   TY     G + + I      I  SPY++ + ++      V + + ++  GL  K T  F + ++ +
Sbjct:   24 DKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIGLLEVLSQKKM--FRKYNQRPTFRQMQLENVSVALEFLDRENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDTDDAKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADEWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPK---KARAYGPGIEPTGNVVMKKAVFTVETIS-------------AGQGEVLVYVEDPAGHREEAK-----------------VTANNDKNRTYSVFYIPKVTGMHKVTVLFA--GLHISKSPFEVDVGMAQGDSSKVTAQGPGLEAVGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECQIEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVSVGEACNPSLCVAKGRGLQPKGLRIKETAEFKVYTKGA 512          

HSP 2 Score: 99.7525 bits (247), Expect = 2.688e-20
Identity = 102/329 (31.00%), Postives = 139/329 (42.25%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +       +F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN  +IP SPF + VA   D  RR+        + S  E   K N  +   V  N     +   V SP      C VTE                 ++D + +       G+Y ID   F G  I G  +K+++                  Q  +P +V+       AYG GL+         F +   N S +      +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  +
Sbjct: 2104 HKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDENIPDSPFVVPVASPSDDARRL-------TVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTE----------------IDEDKYAVRFIPRENGLYLIDV-KFNGSHIPGSPFKIRVGEAG--------------QAGDPGMVS-------AYGAGLEGGNTGSPCEFIV---NTSSA---GPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKARI 2381          

HSP 3 Score: 75.8702 bits (185), Expect = 5.220e-13
Identity = 82/319 (25.71%), Postives = 131/319 (41.07%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN    F V+T     G L++ IEGPSKA+IS +D + G   VSY   +PG+Y   + +N   IP SP+   +  D + R+ H  V             G++  I          +   ++  L   +T P G      +K +     ++G + V             +F+  +IG      + NI  + R    S  + + I    I +     +   G GL +A       F I      ++       L ++I+GPSKV I+  +  +G     Y P   G Y I I ++++ H+PGS F + V
Sbjct: 1733 VTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPYVAKITGDDSMRMSHLKV-------------GSAADIP-------LDIGELDLSQLTASLTTPSGREEPCLLKML-----RNGHVGV-------------SFVPKEIGE----HLVNIKKNGRHIP-SSPISVMINQSEIADA--SRVRVSGQGLSEARTFEPAEFII------DTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQ-HVPGSAFTVKV 1999          

HSP 4 Score: 75.0998 bits (183), Expect = 9.092e-13
Identity = 80/315 (25.40%), Postives = 142/315 (45.08%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNS-TSIKPVGKNLIFHVSSPEILNLNCFVTEPHG---GSSFHPIKKMSK---TSNKDGFINV-FAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNH 5900
            +GK      +C    ++ ++  ++ + G + + Y    PG+YV  + F    IP+SPF++   +  +   L +  +  +       N G    + +P+G N +  V+     +L    T   G   G    P  K+++     NKDG + V +A T  G++ +D              +K + IH  +  + L   VD        VN    ++ AYG GL    VN+     +F  N  ++    E  L + I+GPSK  ISC+++ +G     Y+P++ G Y I + Y++K HIPGSP+   +  D +  ++H
Sbjct: 1548 AGKGKVTCTVCTPDGAEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVMALEGASPEQLMQQTQ--VPQYAYAPNMGQPWATDRPMGMNGL-DVAGLRPFDLVIPFTIQKGEVTGEVRMPSGKVARPEIADNKDGTVTVKYAPTEAGLHEMD--------------IKYDGIH--IPGSPLQFYVD-------YVNS--GHVTAYGPGLIHGMVNKPA---VFTVNTKDA---GEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDK-HIPGSPYVAKITGDDSMRMSH 1827          

HSP 5 Score: 67.0106 bits (162), Expect = 2.372e-10
Identity = 41/123 (33.33%), Postives = 59/123 (47.97%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            SF   P   G++ I I        I   PF V V        + ++GPGL   V      F+++  G D   +GFS+EGPS  KIEC + G+GS  + Y    PG Y + ++   E+I  SP+
Sbjct:  542 SFEYYPTTPGNYIITITWG--GQHIPRSPFEVKVGTEAGAQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQHSPF 662          

HSP 6 Score: 61.6178 bits (148), Expect = 1.221e-8
Identity = 36/128 (28.12%), Postives = 67/128 (52.34%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            K   ++    P  +G  ++ IK +   + I   P +  V+  N    + +YGPGL   + + P VF ++T +  +  +  ++EGPSK  I C +  +G+  ++Y  +LPG Y + +  N+++I  SPY
Sbjct: 1689 KDGTVTVKYAPTEAGLHEMDIKYD--GIHIPGSPLQFYVDYVNSG-HVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPY 1813          

HSP 7 Score: 60.8474 bits (146), Expect = 1.753e-8
Identity = 86/341 (25.22%), Postives = 142/341 (41.64%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPE--ILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSD 5891
            ++E  D S+    V V G+ L +       +F++ T     G L++ IEGPSK +I+  D++ G   V+Y  T PG Y+  I F    +P S F + V  +         +K  I        K  + S+  VG      +  PE  I ++   VT P G    H  + M +  N    I    + +GV+ +            S K + +++ GS    T         + PL     ++ + A G GL++A       F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++++ +IP SPF + V   P+ D
Sbjct: 1906 QSEIADASR----VRVSGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGE-------GRMKESI------TRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSG--KVHKAEIM-EGENNTYCIRFVPTEMGVHTV------------SVKYQGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGPGLERAEAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDE-NIPDSPFVVPV-ASPSDD 2196          

HSP 8 Score: 58.151 bits (139), Expect = 1.161e-7
Identity = 52/197 (26.40%), Postives = 90/197 (45.69%), Query Frame = 3
Query:  924 RVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + DL +KIP I   IA ++  +    +G V+K        ++N      +P   G   + +K       +   PF+  V    +     + + GPGL  + A  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N+ENI DSP+  V+  ++  D+ +++ V  L+    K
Sbjct: 2024 QCDLSLKIPEIS--IA-DMTAQVTSPSGKVHKAEIM--EGENNTYCIRFVPTEMGVHTVSVKYQ--GQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDENIPDSPF--VVPVASPSDDARRLTVASLQESGLK 2211          

HSP 9 Score: 55.0694 bits (131), Expect = 1.191e-6
Identity = 40/115 (34.78%), Postives = 49/115 (42.61%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVK 5213
            + V TE+G       +V   G  L  G V  +  FVV   G   G L   +EGPS A+I   DK  G   V Y  T PGEY   +     DI HSPF   +    +R      VK
Sbjct:  571 VKVGTEAG-----AQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQHSPFMAEIKPAPDRDFYPDKVK 680          

HSP 10 Score: 53.1434 bits (126), Expect = 3.796e-6
Identity = 41/133 (30.83%), Postives = 58/133 (43.61%), Query Frame = 3
Query: 4827 KPTDMKQNILRLDSISVKTESGDLSQIPYEVHV---IGKALC---------KGF-VNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIG--IYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD 5180
            KPT   Q+I     I +    G +S+ PY V V      +LC         KG  +    +F V+T G   G L + I+GP   E     K +G  +Y   Y  T PG Y+  I++    IP SPF + V  +
Sbjct:  449 KPTQEGQHI-----IYITFAGGQISKSPYTVSVGEACNPSLCVAKGRGLQPKGLRIKETAEFKVYTKGAGTGELKVTIKGPKGLEEPCKKKDLGDGVYSFEYYPTTPGNYIITITWGGQHIPRSPFEVKVGTE 576          

HSP 11 Score: 53.1434 bits (126), Expect = 4.306e-6
Identity = 36/113 (31.86%), Postives = 55/113 (48.67%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK 1466
            + N PFRV V        +  +GPGL   + + P  F ++T G+        MEGPS+ K+ C +  +GS  + Y    PG Y L+I    + I  SP+S+ +   + VD  K
Sbjct: 1218 VPNSPFRVPVTEGCDPARVRVHGPGLKAGLTNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCSVEYIPYEPGTYNLNITYGGQPITGSPFSVPV--QDTVDPTK 1328          
BLAST of Filamin A vs. Ensembl Cavefish
Match: flncb (filamin C, gamma b (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-041008-175])

HSP 1 Score: 161.384 bits (407), Expect = 6.027e-39
Identity = 136/488 (27.87%), Postives = 222/488 (45.49%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNL----PNK-KPT---IVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            KI++  FTRW N  LK  NK I DLQ DL +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + E+  DE  K        L W+ +K+    I+N    W  G A+G +V+ C   LC D   W+ +  + NA+ AM+ A     +PQ++ P EI+D +  + ++MTY+SQF     +     R+   +    K     I+  GN  M  A    +                ++ G  ++L+ I   E    +  V+   DKN                  S   +P + G     +K      +I + PF V V+     PNK +PT   I + G G  G V    GV I+D+ G    +   +E          N G+     TY  +L G + + +    + I  SP+++ I +++  +  + +   GL+ K  +
Sbjct:   16 KIQQNTFTRWCNEHLKCMNKKIGDLQRDLSDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDAKKLTPKQRLLGWIQNKVPQLPINNFHRDWRDGKALGALVDNCAPGLCPDWEMWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKTLHPKRAKAYGPGIEPRGNMVMRPAEFVVET---------------VEAGLGEVLVYIEDPEGHTEEARVIPNNDKN---------------RSYSVVYLPKVEGLHK--VKVLFAGQDINHSPFLVNVSKALGDPNKVQPTYFDIYTAGAGA-GDV----GVIIVDSQGRRDTVEIILE----------NKGDSVFRCTYGPVLEGPHVIYVTFAGQQIPRSPFTVHISEASNPNACRAIGR-GLQPKGVR 455          

HSP 2 Score: 110.153 bits (274), Expect = 2.049e-23
Identity = 102/329 (31.00%), Postives = 144/329 (43.77%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRI---TVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN-----LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   V+Y V  PG+Y  +I FN   IP SPF +   T++DD  R          + S  EM  K N  +   V  N     +   V +P      C++TE       H I+ + + +             GV++ID   F G  I G  +K+++                  Q+ +P +V+       A+G GL+  T    + F +   N          +L VTIDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2142 HKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSIKFNDEHIPDSPFIVPIATLSDDARRLT--------VTSLQEMGLKVNHEASFAVQLNGARGVIDAKVHTPSGAVEECYITELDNDK--HAIRFIPREN-------------GVHSIDV-RFNGSHIPGSPFKIRVGEPG--------------QVGDPGMVS-------AFGPGLEGGTTGVPSDFIVNTCNAGSG------ALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV 2419          

HSP 3 Score: 78.1814 bits (191), Expect = 9.990e-14
Identity = 93/408 (22.79%), Postives = 161/408 (39.46%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGG-SIGFVLE----GPIETQV--QCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSP 2273
            PI +G + + I    ++  I   PF V V+       + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+                           + I+ + N  F  P  V+C+   G+     +V +  +  F I+       +L ++        EG+P  I   D+ +        STF      C+ I  + +   I        + T  +V V     ++ I   +  E+             + +YG  +    +K  E     +D   + QG  SIG        GP E  +       D+  + +K+ P  AG+Y + V    + I  SPF I V  + D        P
Sbjct:  504 PIFTGKYTVIITWGGHA--IPRSPFEVVVSEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPF--------------------------MAHILPAANDVF--PEKVKCYGP-GLEPTGCIVNKPAE--FTIDARGAGRGQLKIYA----QDSEGYPIDIQITDNGD--------STFF-----CVYIPTKPIKHTI--------IITWGEVNVPNSPFRVTIGEGSHPEN-------------VKVYGPGVEKSGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFADQEIPISPFRIKVDPSHDANKVKAEGP 840          

HSP 4 Score: 67.0106 bits (162), Expect = 2.859e-10
Identity = 84/356 (23.60%), Postives = 138/356 (38.76%), Query Frame = 3
Query: 4866 SISVKTESGDLSQIPYEVHVI-----GKALCKG-----FVNFNNKFVVHTSGKIPGNLAIC--IEGPSKAE--ISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +I++K    ++   PY +H +      K L  G      +    + V+    K  G   +   +  P  AE  +  ++   G + + Y    PG+YV  I F    IP+SPF + V   ++  + ++  K  I  EV M          P GK    H+                             T NKDG + V +A T  G++ +D   + G+ I G   +  ++ I+                           ++ AYG GL    VN+ + F I   +  E        L + ++GPSK +ISC ++ +G     Y+P   G Y I + + +K HIPGSPF   +  D
Sbjct: 1576 TITIKYGGDEIPYSPYRIHALPSGDASKCLVTGSGLGPTIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENSDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVVRTFLSFDLQYR--KLCIMGEVRM----------PSGKTARPHI-----------------------------TDNKDGTVTVKYAPTEKGLHEMDI-KYDGNHIPGSPLQFYVDAINSG-------------------------HVTAYGPGLSHGMVNKPSIFTIVTKDAGEG------GLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDK-HIPGSPFTAKITGD 1857          

HSP 5 Score: 64.6994 bits (156), Expect = 1.203e-9
Identity = 37/92 (40.22%), Postives = 47/92 (51.09%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRR 5192
            V   G  L  G VN  + F + T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y   + F+   IP SPF   +  D + R
Sbjct: 1770 VTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKITGDDSMR 1861          

HSP 6 Score: 64.6994 bits (156), Expect = 1.320e-9
Identity = 82/338 (24.26%), Postives = 137/338 (40.53%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTS--GKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKP-DICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV--LRDPN 5885
            P +V   G  L +G VN    F V  S  G+    + I  +  ++AE+   +   G Y ++Y     G Y   I++    +P  P R+ V    D    ++    V+P  +  EV      ++ +    G N I   + +P   N + ++T+   G+      ++  T+ +DG   I V    + V              P    ++        S T  CD                 + AYG GL++  VN+ N F +      E+       L + I+GPS+ ++SC ++ +G     YIP   G Y + IT+     IPGSPF++ V  L DP+
Sbjct: 1120 PSKVTASGPGLERGKVNEAASFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITINYGGHAVPKFPARVQVDPAVDTSGVKVFGPGVEPRGVLREVTTHFIVDTRAHNKTGGNHIKTRIVNPSGSNTDAYITDKGDGTY-----RVEYTAYEDGVHLIEVLYDEVSV--------------PKSPFRV--------SVTEGCDP--------------SRVRAYGPGLEEGLVNKPNRFTV------ETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGG-LPIPGSPFRVPVRELVDPS 1409          

HSP 7 Score: 64.3142 bits (155), Expect = 1.510e-9
Identity = 84/340 (24.71%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSP---EILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGP---SWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVI---GLYFIGITYSNKCHIPGSPFKITV 5870
            ++E GD S+    V V GK L +G      +F+V T     G L + IEGPSK +I+  D + G   V+Y  T PG Y+  I F    +P SPF + V  +  ++               +  +  + SI  VG     ++  P       +   VT P G           KT + +    +       Y++    F+  ++GP   + K + +++ GS    T         + PL     ++ + A G GL +        F I  W            L + ++GPSK +IS  +  +G   C +  V+   G Y + I ++++ HIP SPF + +
Sbjct: 1943 QSEIGDASK----VKVFGKGLVEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDVEDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRKK-------------ESITRRRQAPSIASVGSTCDLNLKIPGETSTREMTAQVTSPGG-----------KTDDAE----IIEGEDSTYSV---RFVPQEMGPHTVNVKYRGQHVPGSPFQFT---------VGPLGEGGAHK-VRAGGTGLDRGVAGVPAEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGS--CGVAYVVQEPGDYEVSIKFNDE-HIPDSPFIVPI 2228          

HSP 8 Score: 62.7734 bits (151), Expect = 5.600e-9
Identity = 40/132 (30.30%), Postives = 66/132 (50.00%), Query Frame = 3
Query: 1047 SNEL-SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFS-MEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +NE+ +   IP   G + + I  N     +   PF V   +P     + +YGPGL G +   P  F +DT G+        +EGP + KIEC + G+GS  ++Y    PG Y ++I+  + +I  SP+  ++
Sbjct:  985 ANEVHTVKYIPPEEGPYKVDI--NYDGNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYAINILFADAHIPGSPFKAMV 1114          

HSP 9 Score: 57.3806 bits (137), Expect = 2.095e-7
Identity = 40/130 (30.77%), Postives = 66/130 (50.77%), Query Frame = 3
Query: 1050 NELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNK--KPTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            ++ +   IP  +G   I ++ N     I   PF++ V  P +   P +VS +GPGL G     P  FI++T N     +  +++GPSK K++C     G   +TY+ + PG Y +SI     ++I  SP+
Sbjct: 2289 DKHAIRFIPRENGVHSIDVRFN--GSHIPGSPFKIRVGEPGQVGDPGMVSAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEG-YKVTYTPMAPGSYLISIKYGGPQHIVGSPF 2415          

HSP 10 Score: 54.299 bits (129), Expect = 1.958e-6
Identity = 36/139 (25.90%), Postives = 65/139 (46.76%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             +  S  P   G   + +KKN     + N PF++ V          +  +G GL          FI+DT  +    +G S+EGPSK  I C ++ +G+  +TY    PG Y ++I   ++++  SP+++ ++   +  E
Sbjct: 1908 HIGISFTPKEVGEHVVSVKKN--GKHVTNSPFKIMVGQSEIGDASKVKVFGKGLVEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDVEDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLGEGRKKE 2044          

HSP 11 Score: 51.9878 bits (123), Expect = 8.589e-6
Identity = 33/132 (25.00%), Postives = 65/132 (49.24%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            K   ++    P   G  ++ IK +     I   P +  V+  N    + +YGPGL   + + P +F I+  +  +  +  ++EGPSK +I C +  +G+  ++Y    PG Y + +  ++++I  SP++  I
Sbjct: 1726 KDGTVTVKYAPTEKGLHEMDIKYD--GNHIPGSPLQFYVDAINSG-HVTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKI 1854          
BLAST of Filamin A vs. Ensembl Cavefish
Match: flnca (filamin-C [Source:NCBI gene;Acc:103033794])

HSP 1 Score: 151.754 bits (382), Expect = 4.765e-36
Identity = 135/507 (26.63%), Postives = 227/507 (44.77%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIG------KSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGL-----LQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRV----CVNLPNKKPTIVSYGPGL--YGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            EM  T+ E+ +     KI++  FTRW N  LK  NK + DLQ DL +G  L+ L+E+LSQKK+ +      + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  ++W LI HYSI   + +++ DE        +  L W+ +K+    I+N +  W  G A+G +V+ C   LC D   W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF           +    +    K     I+  GN  M  A  + + + D  +            G V + ++ P   ++ AK +                  N  K    S S +P ++G     +K      +I   PF V     V  PNK   + + GPGL   G+V   P  F + T G+    +   +  P   K    +   N G+     TY  +L G + + +    + I  SP+ + I +++     +     GL+ K  +
Sbjct:   28 EMPATEKELAEDAPWKKIQQNTFTRWCNEHLKCINKNVTDLQRDLGDGLKLIALLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDRERIKLVSIDSKAIVDGNLKLILGMIWTLILHYSISMPMWDDDDDEEKKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWETWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPRQLHPKKAKAYGPGIEPEGNMVMKPAVFTVETL-DAGL------------GEVIVYVEDPEGYREEAKVVP-----------------NNDKKRTYSVSYVPKVAGPHK--VKVLFAGQDIDKSPFSVNVAKTVGDPNK---VQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEASNASSCRATGR-GLQPKGVR 498          

HSP 2 Score: 114.005 bits (284), Expect = 1.407e-24
Identity = 101/330 (30.61%), Postives = 138/330 (41.82%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRI---TVADDVNRRILHKHVKPDIC----SEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            P++V   G  L +G      +F + T     G L+I +EGPSKAEISF D+K G   VSY V  PG+Y  +I FN   IP SPF +   T++DD  R  +    + D+     +   +Q  G    I          V SP  +   C++T+     S                I       GV++ID   F G  I G  + V++ E  H                 +P +V+       AYG GLQ         F +   N          +L VTIDGPSK ++ C+E   GY   Y P+  G Y I I Y    HI GSPFK  +
Sbjct: 2285 PHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEASFAVQRNGARGVIDA-------KVHSPSGVVEECYITDVDADKS---------------AIRFIPRENGVHSIDV-KFNGSHIPGSPFNVRVGETGHAG---------------DPGLVS-------AYGPGLQAGCTGVPAEFVVNTCNAGSG------ALSVTIDGPSKAKMDCVECAEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKI 2563          

HSP 3 Score: 92.0485 bits (227), Expect = 7.183e-18
Identity = 97/324 (29.94%), Postives = 134/324 (41.36%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFV-TEP--HGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISC--IEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  LC G VN    F V T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y   + F+   IP SPF   +  D + R    +V     S  ++  K   T +     +L   + +P      C + T P  H G SF P K++ +       ++V  S   V N  F   +G  +IG + +V+                                   A+G GL +A       FF+   N           L ++I+GPSKV I C  +ED    +  Y P   G Y I I ++ K HIPGSPF + V
Sbjct: 1836 VTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQLNVG----SAADVSLKITETDL----SSLTASIRAPSGAEQPCLLKTLPNRHIGLSFTP-KEVGEHE-----VSVKKSGKHVNNSPFKIMVGPSEIGEASRVR-----------------------------------AFGKGLMEAHTFEVAEFFVDTRNAGYG------GLGLSIEGPSKVDIKCEDVEDGTCRV-TYCPTEPGNYIINIKFAEK-HIPGSPFTVKV 2102          

HSP 4 Score: 69.3218 bits (168), Expect = 5.930e-11
Identity = 46/161 (28.57%), Postives = 79/161 (49.07%), Query Frame = 3
Query: 1074 PILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT-------KSFIIDSRNS 1532
            P + G + + I        I   PF V V +      + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +      +KV+  G   + T         F ID+R +
Sbjct:  547 PTVPGKYTVTITWG--GQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQA 705          

HSP 5 Score: 66.6254 bits (161), Expect = 3.292e-10
Identity = 96/392 (24.49%), Postives = 158/392 (40.31%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDK----------IGPSWKV-------------KIENIHGSLRSTTLSCDVDIQ---------IINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SVK     ++  P+++ V    IG     +A  KG +  +     +F V T     G L + IEGPSK +I   D + G   V+Y  T PG Y+  I F +  IP SPF + V  +  +   I+ K   P I S     ++ ++  GN   +    + L   F  SS          +++  GG +     +++ +K   +D F ++F S +G  ++  +  L  K            P  KV              +  +   + S T+S     Q          + PL     ++ + A G GLQ+        F I  W            L + ++GPSK +IS  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 1989 VSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKESIMRKRQAPSIASVGTICDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVHVEESTKVGGRDPFRDIFGSILGRESLGCFGSLTSKEDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHK-VRAGGTGLQRGIAGVPTEFSI--WTREAG----AGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNE-HIPDSPFIVPI 2372          

HSP 6 Score: 62.3882 bits (150), Expect = 6.665e-9
Identity = 50/195 (25.64%), Postives = 87/195 (44.62%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNT---KSFIID-SRNSTFEM 1544
            N+ V+ V  +G    C    + +K    +   IP   G + + +  +     +   PF V   +P     + +YGPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y     G Y ++I+  E++I  SP+   +  +     +  V   GLE        +F +D SR    E+
Sbjct: 1006 NVGVKMVSPSGRPIPCKLEPDRAK-GVTNVKYIPPEEGQYKVDVSYD--GNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPALDASRV-TVSGPGLERAKAGEVATFTVDCSRAGEAEL 1196          

HSP 7 Score: 60.077 bits (144), Expect = 3.488e-8
Identity = 73/290 (25.17%), Postives = 116/290 (40.00%), Query Frame = 3
Query: 5028 PSKAE--ISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV-FAST-IGVYNIDFYNFLGDKI-GPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            P  AE  +  ++   G + + Y    PG+YV  I F    IP+SPF +            +  K  +    E Q +      +P+   + F V       L   V  P G ++   I+      NKDG + V +A T  G++ +D   + G+ I G   +  ++     +                         + AYG GL   TVN+   F +   N +E        L + ++GPSK +ISC ++ +G     Y+P   G Y I + +  K HIPGSPF   +  D
Sbjct: 1692 PDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHV------------QATKEPVVPRDEKQPQ-----FRPINLLIPFTVQQGA---LTGEVRMPSGKTARPLIR-----DNKDGTVTVKYAPTERGLHEMDI-KYDGNHIPGSPLQFFVDAAESGM-------------------------VTAYGPGLCHGTVNKPATFTVVTKNAAEG------GLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGK-HIPGSPFTAKITGD 1923          

HSP 8 Score: 58.151 bits (139), Expect = 1.360e-7
Identity = 37/139 (26.62%), Postives = 69/139 (49.64%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             +  S  P   G  ++ +KK+     + N PF++ V      +   + ++G GL  +       F +DT N     +G S+EGPSK  I+C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 1974 HIGLSFTPKEVGEHEVSVKKS--GKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKE 2110          

HSP 9 Score: 55.0694 bits (131), Expect = 9.634e-7
Identity = 72/306 (23.53%), Postives = 124/306 (40.52%), Query Frame = 3
Query: 4986 SGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV---ADDVNRRILHKHVKPD-ICSEVEMQNKGNSTSIKPVGKNLI-FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            +G+    + I  +  + AE+   +   G + V+Y     G Y  +I +    +P  P RI V    D    ++    V+P  +  +V      ++ +   +G N I   + +P   N +  +T+   G+      ++  T+ +DG   I VF   + V              P    ++  + G        CD                 + AYG GL+   VN+ N F +      E+       L +TI+G S+ ++SC ++ +G     Y+P + G Y I ITY  +  IPGSPF + V RD
Sbjct: 1191 AGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTY-----RVEYTAFEDGLHLIEVFYDEVAV--------------PKSPFRVSVVEG--------CDP--------------SRVRAYGPGLEGGIVNKPNCFTV------ETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQ-PIPGSPFHVLV-RD 1447          

HSP 10 Score: 54.299 bits (129), Expect = 1.779e-6
Identity = 47/192 (24.48%), Postives = 88/192 (45.83%), Query Frame = 3
Query:  960 KDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSL--IPILSGSFDIFIKKNEYSMEILNKPFRVCVNL-----PNKKPTIVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSF 1511
            K+  + +  +     G V     N    +S + ++S+  +P   GS  + +K +     +   PF+  V       P+K   + + G GL   +A  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  D+ +++ V  L+ K+ + +
Sbjct: 2215 KEDVQGMTAQVTSPGGKVV----NAELVESGDSTYSVRFVPTEMGSHTVSVKYS--GQHVPGSPFQFTVGPLGEGGPHK---VRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DDARRLTVTSLQEKDLRVY 2395          

HSP 11 Score: 53.9138 bits (128), Expect = 2.407e-6
Identity = 85/326 (26.07%), Postives = 124/326 (38.04%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKP-VGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDG--FINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATV--NRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING--YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKI 5864
            P  V   G  L  G VN  N F V T G   G L + IEG S+A++S  D K G   V Y   IPG Y   I++    IP SPF + V D V+             S+V+    G  + ++  V +      S   + +L+  +  P G +   P+  +   +N DG   +N   S  G Y +       D     +KV     H +                          + A G GL +A V  +    F I   +  E ++  +      +D   K + + I+D     Y   Y+P V G Y I I Y     IP SP+ I
Sbjct: 1358 PSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVD------------ASKVKCSGPGLGSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGAT--EPVAVL---NNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDA------------------------SKVRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQ-----ILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGD-QIPFSPYSI 1636          

HSP 12 Score: 53.1434 bits (126), Expect = 4.190e-6
Identity = 35/121 (28.93%), Postives = 60/121 (49.59%), Query Frame = 3
Query: 1125 MEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            + +   PFRV V        + +YGPGL G + + P  F ++T G+       ++EG S+ K+ C +  +GS  + Y   +PG Y ++I    + I  SP+ +++     V +  KVK  G
Sbjct: 1341 VAVPKSPFRVSVVEGCDPSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLV---RDVVDASKVKCSG 1458          

HSP 13 Score: 53.1434 bits (126), Expect = 4.297e-6
Identity = 41/135 (30.37%), Postives = 63/135 (46.67%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKK--PTIVS-YGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVI 1436
            +++ +   IP  +G   I +K N     I   PF V V        P +VS YGPGL       P  F+++T N     +  +++GPSK K++C     G   I Y+ + PG Y +SI     ++I  SP+   I
Sbjct: 2432 ADKSAIRFIPRENGVHSIDVKFN--GSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEG-YKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKI 2563          
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004210.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004210.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.9821 bits (245), Expect = 9.904e-21
Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3
Query:  357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+  KL    I N S  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     + Q++ P EI+D +  + ++MTY+SQF
Sbjct:    5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140          

HSP 2 Score: 70.8626 bits (172), Expect = 3.297e-12
Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927
            + A+G GL++ T      F +      ++      SL V IDGPSKV++ C E   GY FCY+P   GLY + I Y    HI GSP++  V   P     H   E   FL
Sbjct: 2023 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2125          

HSP 3 Score: 66.2402 bits (160), Expect = 9.444e-11
Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3
Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
             I   PF V V+       + ++GPGL   +A     F+++  G+D   +GFS+EGPS+ +I C + G+GS  + Y    PG Y + ++ +EE++  SP+   I+ +++
Sbjct:  440 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 548          

HSP 4 Score: 64.6994 bits (156), Expect = 2.747e-10
Identity = 39/96 (40.62%), Postives = 48/96 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRIL 5198
            V   G  L  G V  +  F + T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y  A+ F    IP SP+  RI   +D  R  L
Sbjct: 1762 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASL 1857          

HSP 5 Score: 63.5438 bits (153), Expect = 6.422e-10
Identity = 68/290 (23.45%), Postives = 111/290 (38.28%), Query Frame = 3
Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLI------------FHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888
            G + + +  T PG YV A+ F    IP+SPF + V      R       P        Q    S +    G +L             FH+  P  L       E H  S      ++    N+DG ++V  + I  G++ +D  YN      G   +  ++ + G                          ++ AYG GL    V +   F I      ++    E  L + ++GPSK +ISC ++ +G     Y+P   G Y I + ++ + HIPGSP+   ++   +S
Sbjct: 1597 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGP-------------------------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIIAGEDS 1852          

HSP 6 Score: 60.8474 bits (146), Expect = 4.082e-9
Identity = 112/518 (21.62%), Postives = 198/518 (38.22%), Query Frame = 3
Query:  804 SSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNIL---VTELEKKYFRI-ECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKF----------GLILYGTSLSGRP--IKKGE---------CQVVQIDLDRSIQG--------------GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDG-KSIDGSPFSITVS 2234
            S    D G +  M   IST+++  +H+      P  ++ G +   + +P+  K  A   +++            R+G       +S S  PI  G  ++ IK N + +     P +  V+     P++ +YGPGL   +      F +DT +  +  +  ++EGPSK +I C +  +G+  ++Y    PG Y +++    ++I  SPY                ++I  E+    S +  SR ST ++             S  IL     +LE    R+  CP    +   V V +    + G P+ +      E  R+V      S L E   ++ N     A+ L+     +    +  V+T +  +    E    S++   KWI  +F           +   G S+ G P  ++ GE                L+R   G              GS+   ++GP + +V C    +G Y   + P   G Y + +   G   I GSP+   V+
Sbjct: 1660 SQTCGDAGLSLAMSEDISTESLRPFHLVV----PFSLRKGHITGEVHMPSGRK--ASPRIID-----------NRDGT------MSVSFAPIEKGLHEMDIKYNGHHIPT-GSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPY--------------MARIIAGEDSLRASLL--SRGSTHDV-------------SLRILELHCEDLEDGRCRVWYCPPEPGD-YEVSVRFEDEHIPGSPFLLTVDGVCEESRRV----AVSGLLESGWKV-NHPASFAVHLNGAKGRI----EAKVHTPSGSV----ENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEG-YHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVT 2108          

HSP 7 Score: 57.3806 bits (137), Expect = 4.190e-8
Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514
            +   PF +   LP     +  +G GL G     P  F +DT  +    +G ++EGP + ++EC + G+G+  ++Y  +  G Y ++I+  + ++  SP++ V+  S    E   V+V G   +   +F+
Sbjct:  931 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1056          

HSP 8 Score: 55.8398 bits (133), Expect = 1.130e-7
Identity = 69/343 (20.12%), Postives = 139/343 (40.52%), Query Frame = 3
Query: 1329 NGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIK----KVKVIGLENKNTKSFIIDSRNST-FEMPPDVECFDKLGVSSNNILVTELEKKY---FRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDS-NEGQRKVDQFSTFSSLQEKC---LEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKH-------ETFEESQLKTFKWIDKKFGLILYGTSLSGRP---------IKKGECQV-VQIDLDRSIQG-GSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVS---ETSDTGVF 2258
            N ++ + Y+    G + + +  +E+ + DSP+ I +V S+   +++     +   G+E      F + +R +   E+  DV+  D    ++  IL +E+   +   + ++        + + V Y    V G P+ +      + G+ +V+   T   L+  C   + ++ +      +L  + L   T   V  ++      ++H       ET       T+          L    L   P         ++ GE  +  +  +D +  G G +G  +EGP E +++C    DG   + + P+ AG+Y + +      + GSPF+  V    ETS   VF
Sbjct:  708 NDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAEL--DVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGT--KLEMGCEQEVRVVTRGAGGRGQLEAR-LLSPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVF 1045          

HSP 9 Score: 55.0694 bits (131), Expect = 2.348e-7
Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186
            P  V V G  L  G  +  N F + T     G L + +EGP +A ++F +   G + V Y    PGEY+  I++    I   SPF + V D+VN
Sbjct: 1232 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1325          

HSP 10 Score: 51.2174 bits (121), Expect = 3.206e-6
Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183
            P +V V G+ L  G V    +F V T+    G L + +EGP +A +   D   G   VSY     GEY   I F    +P SPF   V   V
Sbjct:  946 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1037          

HSP 11 Score: 49.6766 bits (117), Expect = 9.888e-6
Identity = 33/97 (34.02%), Postives = 45/97 (46.39%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            + V  E+G     P +V   G  L  G    +  FVV   G   G L   IEGPS+A I+  D+  G   V Y  T PG+Y   +  ++ D+  SPF
Sbjct:  448 VLVSAEAG-----PQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 539          
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004223.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235187:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.9821 bits (245), Expect = 1.091e-20
Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3
Query:  357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+  KL    I N S  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     + Q++ P EI+D +  + ++MTY+SQF
Sbjct:    5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140          

HSP 2 Score: 70.8626 bits (172), Expect = 3.343e-12
Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927
            + A+G GL++ T      F +      ++      SL V IDGPSKV++ C E   GY FCY+P   GLY + I Y    HI GSP++  V   P     H   E   FL
Sbjct: 2264 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2366          

HSP 3 Score: 66.2402 bits (160), Expect = 8.289e-11
Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3
Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
             I   PF V V+       + ++GPGL   +A     F+++  G+D   +GFS+EGPS+ +I C + G+GS  + Y    PG Y + ++ +EE++  SP+   I+ +++
Sbjct:  437 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 545          

HSP 4 Score: 64.6994 bits (156), Expect = 2.390e-10
Identity = 37/94 (39.36%), Postives = 47/94 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRIL 5198
            V   G  L  G V  +  F + T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y  A+ F    IP SP+   + +D  R  L
Sbjct: 1699 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASL 1792          

HSP 5 Score: 63.5438 bits (153), Expect = 5.974e-10
Identity = 70/274 (25.55%), Postives = 112/274 (40.88%), Query Frame = 3
Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            G + + +  T PG YV A+ F    IP+SPF +    +            DI +E          S++P      FH+  P  L       E H  S      ++    N+DG ++V  + I  G++ +D              +K    H   RS  L   VD ++  P        ++ AYG GL    V +   F I      ++    E  L + ++GPSK +ISC ++ +G     Y+P   G Y I + ++ + HIPGSP+   +  D
Sbjct: 1574 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAMSE------------DISTE----------SLRP------FHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMD--------------IKYNGHHIPSRSP-LQFYVD-EMDGP--------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIRED 1786          

HSP 6 Score: 58.5362 bits (140), Expect = 2.125e-8
Identity = 35/128 (27.34%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            +   +S S  PI  G  ++ IK N + +     P +  V+     P++ +YGPGL   +      F +DT +  +  +  ++EGPSK +I C +  +G+  ++Y    PG Y +++    ++I  SPY
Sbjct: 1654 RDGTMSVSFAPIEKGLHEMDIKYNGHHIP-SRSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPY 1779          

HSP 7 Score: 57.3806 bits (137), Expect = 3.992e-8
Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514
            +   PF +   LP     +  +G GL G     P  F +DT  +    +G ++EGP + ++EC + G+G+  ++Y  +  G Y ++I+  + ++  SP++ V+  S    E   V+V G   +   +F+
Sbjct:  917 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1042          

HSP 8 Score: 55.0694 bits (131), Expect = 2.371e-7
Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186
            P  V V G  L  G  +  N F + T     G L + +EGP +A ++F +   G + V Y    PGEY+  I++    I   SPF + V D+VN
Sbjct: 1222 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1315          

HSP 9 Score: 52.7582 bits (125), Expect = 1.113e-6
Identity = 41/174 (23.56%), Postives = 77/174 (44.25%), Query Frame = 3
Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT---IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVIVKSNKVDEIKKVKVIGLEN-KNTKSFIIDSRNSTFEM 1544
            S+ ++++   +P  +G   + +  +  S  +   PFRV V  P        + ++GPGL       P  F++DT+G+    +  +++GPSK +++C+  G       Y    PG+Y +SI      +I  SPY            +   ++ G  N   T SF++++      M
Sbjct: 2215 SEIDKVAARFVPRENGVHPVSVTCDGAS--VPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSE-GPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRA---------RVTGPRLSGGHNLHETSSFLVEAGEPRRAM 2376          

HSP 10 Score: 51.2174 bits (121), Expect = 3.235e-6
Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183
            P +V V G+ L  G V    +F V T+    G L + +EGP +A +   D   G   VSY     GEY   I F    +P SPF   V   V
Sbjct:  932 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1023          

HSP 11 Score: 51.2174 bits (121), Expect = 3.345e-6
Identity = 35/127 (27.56%), Postives = 57/127 (44.88%), Query Frame = 3
Query: 1101 FIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-----SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             +   E    + + PFRV V          + + G GL  +       FI+DT    +  GF     SMEGPS+ ++ C ++ +G   + Y    PG Y L+I   EE I  SP+++++    +  E
Sbjct: 1851 LVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDT----RYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQKE 1973          

HSP 12 Score: 49.6766 bits (117), Expect = 9.972e-6
Identity = 33/97 (34.02%), Postives = 45/97 (46.39%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            + V  E+G     P +V   G  L  G    +  FVV   G   G L   IEGPS+A I+  D+  G   V Y  T PG+Y   +  ++ D+  SPF
Sbjct:  445 VLVSAEAG-----PQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 536          
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004195.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004195.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.5969 bits (244), Expect = 1.264e-20
Identity = 49/136 (36.03%), Postives = 75/136 (55.15%), Query Frame = 3
Query:  357 ILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            I+DG++K I  L+W LI HYSI   + E+  D+  K        L W+  KL    I N S  W  G A+G +V++C   LC D   W+    ++NA+ AM+ A     + Q++ P EI+D +  + ++MTY+SQF
Sbjct:    5 IVDGNLKLILGLVWTLILHYSISMPVWEDEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQF 140          

HSP 2 Score: 70.8626 bits (172), Expect = 3.370e-12
Identity = 40/110 (36.36%), Postives = 53/110 (48.18%), Query Frame = 3
Query: 5598 ICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ*FL 5927
            + A+G GL++ T      F +      ++      SL V IDGPSKV++ C E   GY FCY+P   GLY + I Y    HI GSP++  V   P     H   E   FL
Sbjct: 2402 VSAFGPGLERGTTGSPAEFVV------DTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARV-TGPRLSGGHNLHETSSFL 2504          

HSP 3 Score: 66.6254 bits (161), Expect = 7.362e-11
Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3
Query: 1128 EILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNK 1451
             I   PF V V+       + ++GPGL   +A     F+++  G+D   +GFS+EGPS+ +I C + G+GS  + Y    PG Y + ++ +EE++  SP+   I+ +++
Sbjct:  440 HIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASR 548          

HSP 4 Score: 64.6994 bits (156), Expect = 2.801e-10
Identity = 39/96 (40.62%), Postives = 48/96 (50.00%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRIL 5198
            V   G  L  G V  +  F + T     G L++ +EGPSKAEIS  D K G   VSY  T PG+Y  A+ F    IP SP+  RI   +D  R  L
Sbjct: 1756 VTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASL 1851          

HSP 5 Score: 63.1586 bits (152), Expect = 8.006e-10
Identity = 68/298 (22.82%), Postives = 115/298 (38.59%), Query Frame = 3
Query: 5067 GIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPD-----------ICSE---------VEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTI--GVYNIDF-YNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNS 5888
            G + + +  T PG YV A+ F    IP+SPF + V      R       P            +C           + M    ++ S++P      FH+  P  L       E H  S      ++    N+DG ++V  + I  G++ +D  YN      G   +  ++ + G                          ++ AYG GL    V +   F I      ++    E  L + ++GPSK +ISC ++ +G     Y+P   G Y I + ++ + HIPGSP+   ++   +S
Sbjct: 1589 GTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRP------FHLVVPFSLRKGHITGEVHMPSGRKASPRI--IDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGP-------------------------SVTAYGPGLSHGMVGKHAAFTI------DTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIIAGEDS 1846          

HSP 6 Score: 60.077 bits (144), Expect = 6.597e-9
Identity = 36/133 (27.07%), Postives = 66/133 (49.62%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIV 1439
            +   +S S  PI  G  ++ IK N + +     P +  V+     P++ +YGPGL   +      F +DT +  +  +  ++EGPSK +I C +  +G+  ++Y    PG Y +++    ++I  SPY   I+
Sbjct: 1711 RDGTMSVSFAPIEKGLHEMDIKYNGHHIPT-GSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARII 1841          

HSP 7 Score: 57.7658 bits (138), Expect = 3.631e-8
Identity = 33/129 (25.58%), Postives = 64/129 (49.61%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFI 1514
            +   PF +   LP     +  +G GL G     P  F +DT  +    +G ++EGP + ++EC + G+G+  ++Y  +  G Y ++I+  + ++  SP++ V+  S    E   V+V G   +   +F+
Sbjct:  923 VPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV---ETSGVQVFGPGVEKGTTFL 1048          

HSP 8 Score: 55.0694 bits (131), Expect = 2.384e-7
Identity = 32/94 (34.04%), Postives = 46/94 (48.94%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPH-SPFRITVADDVN 5186
            P  V V G  L  G  +  N F + T     G L + +EGP +A ++F +   G + V Y    PGEY+  I++    I   SPF + V D+VN
Sbjct: 1224 PSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVN 1317          

HSP 9 Score: 53.9138 bits (128), Expect = 5.036e-7
Identity = 49/214 (22.90%), Postives = 89/214 (41.59%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT---IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPYSIVIVKSNKVDEIKKVKVIGLEN-KNTKSFIIDSRNSTFEM 1544
            GR++  +  P+      +N  V  +DK+             K + L+   +P  +G   + +  +  S  +   PFRV V  P        + ++GPGL       P  F++DT+G+    +  +++GPSK +++C+  G       Y    PG+Y +SI      +I  SPY            +   ++ G  N   T SF++++      M
Sbjct: 2329 GRIEAKVHTPS---GSVENCFVSEIDKD-------------KWSLLAARFVPRENGVHPVSVTCDGAS--VPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSE-GPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRA---------RVTGPRLSGGHNLHETSSFLVEAGEPRRAM 2514          

HSP 10 Score: 51.2174 bits (121), Expect = 3.066e-6
Identity = 35/127 (27.56%), Postives = 57/127 (44.88%), Query Frame = 3
Query: 1101 FIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-----SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             +   E    + + PFRV V          + + G GL  +       FI+DT    +  GF     SMEGPS+ ++ C ++ +G   + Y    PG Y L+I   EE I  SP+++++    +  E
Sbjct: 1910 LVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDT----RYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQKE 2032          

HSP 11 Score: 51.2174 bits (121), Expect = 3.252e-6
Identity = 32/92 (34.78%), Postives = 41/92 (44.57%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDV 5183
            P +V V G+ L  G V    +F V T+    G L + +EGP +A +   D   G   VSY     GEY   I F    +P SPF   V   V
Sbjct:  938 PSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSV 1029          
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.2117 bits (243), Expect = 1.853e-20
Identity = 82/276 (29.71%), Postives = 133/276 (48.19%), Query Frame = 3
Query:   63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSV---LIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS----FLNWLNSKLDGY---FIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAIST 860
            E  R K+   +   ++KK FT+W+N  L   +  I DL  DL +G +L++L+E+LS +KL K        + RI  L +V   L FL+ + + L+N+   DI+DG+ + I  L+W +I  + I+    E   ++  +S     L W   K  GY    I N +++W  G+A   IV+    DL  +  K   SNA +N Q A   A Q   + +LL P +I      +K+I+TYV  +     +       + GK +  V++    T  M+    T
Sbjct:   44 ERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPK----PTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVETEDNKERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDL-IEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPEDISVDQPDEKSIITYVVTYYHYFSKM--KALAVEGKRIGKVLESAIETDQMIDKYET 312          
BLAST of Filamin A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006506.1 (pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006506.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.5077 bits (223), Expect = 2.489e-18
Identity = 71/232 (30.60%), Postives = 115/232 (49.57%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL---GENNFDEIGKSFLNW---LNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATD-KAIMTYVSQFSGLLQERNNN 776
            +++KK FT+WIN  L+     I DL  DL +G+ L+ L+E LS   +  IR   + R   +  +  VL +L+ + ++L NI   DI+DG+ K    L+W +I HY   +F    G ++  +  +  L W   +   + G    N SS+W  G  +  IV+   R    D+ +     A  N + A+  A     +P+LL P E +D  A D K+I+TYVS     L +++  
Sbjct:    7 RVQKKTFTKWINSHLQQVRMNIGDLYEDLRDGQALISLLESLSGDCI--IREKGRLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHYQNASFAHIEGNHSSMQSRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVH-AHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDP-EDVDVDAPDEKSIITYVSALHNALHKQDGQ 234          
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO46947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL3])

HSP 1 Score: 129.028 bits (323), Expect = 1.520e-29
Identity = 75/221 (33.94%), Postives = 122/221 (55.20%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGK-----SFLNWLNSKL-DGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            KI++  FTRW N  LK   +F+  L+ DLC+G  L+ L+++LSQK+L +       +  +I  ++  L F+  E + L NI+  DI+ G++K I  L+W LI  Y I     +++ DE  K     + L W+ SK+ +   +DN ++ WN G AI  +V+     L  +    +  +AL NAQ AM+ A     IPQ+L P ++++    + ++MTYVS F
Sbjct:  365 KIQQNTFTRWCNEHLKCVKQFVYSLETDLCDGLKLIALLQVLSQKRLPRFNKKPVFKSQKIENVSISLKFIEDENIRLVNIDASDIVKGNLKLILGLIWTLILKYQISMPYLDDDDDENHKMTPKQALLAWVKSKMPESVPMDNFTTHWNDGRAIACLVDAVAPGLLPECEDLDPKDALQNAQQAMKLAQDWLDIPQVLDPADMVNPKVDELSMMTYVSYF 585          

HSP 2 Score: 107.071 bits (266), Expect = 7.974e-23
Identity = 105/362 (29.01%), Postives = 160/362 (44.20%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV-------------IGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHV-SSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY-NFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDING-YIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQE 5906
            I+VK     +S  P++V+V              G  L +G V     F V T    PG LAI +EGP+KAEI+  D   G   +SY  T PGEY   I F   DIP SPF++ V  +V  R   + +K    S++E      S+ +K VG+   F V ++  +  ++  V  P G  S   I  + K               G Y I F     GD +     VK +  H  +  +     V     +P       + + AYG GL      +   F +       ++     +L +++DGP+KV+++C E+ +G Y   Y P+V G Y I I ++ + HIP SP+ +T+   P+  L H E
Sbjct: 2961 INVKYRGRHISGSPFKVYVEAPVWGGAAKCTAAGPGLERGVVGHPGDFTVWTRDAGPGGLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADEDIPGSPFKVFVTTEVEDRF--RDLK---LSDLE------SSGLK-VGQPASFSVQTNAPVGKVSATVIAPSGTESKAVISDLGK---------------GNYAIRFVPKEFGDHL---VNVKFDETH--IPGSPFKIRVGGGGAHP-------EKVKAYGPGLSSGHAGKSAEFTV------NALEAGSGALALSVDGPAKVKMNCTENQDGTYQVTYYPVVAGEYTISIKFAGQ-HIPDSPYNVTIF-PPSGHLQHSE 3275          

HSP 3 Score: 85.8853 bits (211), Expect = 1.650e-16
Identity = 98/350 (28.00%), Postives = 147/350 (42.00%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHVI-----------GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN--LNCFVTEPHGGSSFHPIKKMSKTSNKDGFINV--FASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV       ++ PYEV V            G  L +G  N    F V T G    +L   IEGP++AEI  +D   G   V+Y   +PG+Y   ++   VDI +SPF + ++   +             S+V  +  G        G    F V + E  +  ++  V +  G  S   IK      NKDG   V  +    G++ +  +    DK  P    K+ NI     + T  C                    AYG GL++  V+++N F I      E+    E  L +TI+GPS+ +I CI++ +G     Y P   G Y + I Y++K HIPGSPFK  +
Sbjct:  981 VSVTWSGEQAAKSPYEVKVATAVDASRIKAYGPGLERGIANKPCHFTVETKGAGVDSLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGD------------ASKVYAKGPGLEPEGVCAGCPAEFTVYTNEAGDGDVDIKVMDSQGKKSPSEIK-----DNKDGTYTVTYYPDKPGMHTVAVH--FNDKPIPKSPFKV-NI---CSTNTSKCR-------------------AYGPGLEKGFVDQRNDFKI------ETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADK-HIPGSPFKARI 1281          

HSP 4 Score: 78.5666 bits (192), Expect = 3.332e-14
Identity = 90/355 (25.35%), Postives = 145/355 (40.85%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRIL---HKHVKPDICSEVE--MQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHG----------GSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKI-GPSWKVKIEN-IHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKI---TVLRDPNSDLNHQEFEN 5915
            +V V G  L KG      +F V+T     G L + IEGPSKAEI+ +D + G   V Y  T PG+Y   I F    +P SPF+  +       I+      V+ +    V    ++  +  +  P   + +F +    + +L   V  P G          G++ + I+ M K S +   INV              + G  I G  +KV +E  + G     T                       A G GL++  V     F ++  +           L + ++GP+K +I+C ++ +G     Y+P   G Y I I ++++  IPGSPFK+   T + D   DL   + E+
Sbjct: 2782 KVKVTGDGLRKGVTGEPARFTVNTRDAGYGGLGLSIEGPSKAEINCVDNEDGTCSVDYLPTEPGKYTINIKFADEHVPGSPFKANIRRPGEEEIVAMSEDGVESEPTQRVSQVFEDLVSFGAAAPQPHDFVFDLKGYNVEDLETTVISPDGEVLPAEIVESGTNSYTIRFMPKESGEH-VINV-------------KYRGRHISGSPFKVYVEAPVWGGAAKCT-----------------------AAGPGLERGVVGHPGDFTVWTRDAGPG------GLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADE-DIPGSPFKVFVTTEVEDRFRDLKLSDLES 3092          

HSP 5 Score: 70.8626 bits (172), Expect = 6.031e-12
Identity = 46/184 (25.00%), Postives = 85/184 (46.20%), Query Frame = 3
Query:  918 DGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNK-PFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEI 1463
            DG +D+ ++ P  E+       V+  + N   Y C                       F  ++    +S E   K P+ V V        I +YGPGL   +A+ P  F ++T G+    +GF++EGP++ +I+C ++G+G   +TY  L+PG Y + +   + +I +SP+ + I  +    ++
Sbjct:  941 DGELDVFVEGPLGEEK------VDIKNNNDGTYSCI-----------------YFPSKFGKYVVSVTWSGEQAAKSPYEVKVATAVDASRIKAYGPGLERGIANKPCHFTVETKGAGVDSLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGDASKV 1101          

HSP 6 Score: 63.929 bits (154), Expect = 8.994e-10
Identity = 48/158 (30.38%), Postives = 73/158 (46.20%), Query Frame = 3
Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            S +N  +   +P  SG   I +K       I   PF+V V  P         + GPGL   V   PG F + T +     +  ++EGP+K +I C + G+GS  I+Y    PG Y + I   +E+I  SP+  V V +   D  + +K+  LE+   K
Sbjct: 2942 SGTNSYTIRFMPKESGEHVINVKYR--GRHISGSPFKVYVEAPVWGGAAKCTAAGPGLERGVVGHPGDFTVWTRDAGPGGLAIAVEGPAKAEITCHDNGDGSCNISYLPTAPGEYTIHIRFADEDIPGSPFK-VFVTTEVEDRFRDLKLSDLESSGLK 3096          

HSP 7 Score: 61.6178 bits (148), Expect = 4.181e-9
Identity = 45/162 (27.78%), Postives = 78/162 (48.15%), Query Frame = 3
Query: 1029 NGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            N   +  N LS S +P  +G   + +KK+     +   PF V V+ P       +   G GL   V   P  F ++T  +    +G S+EGPSK +I C +  +G+  + Y    PG Y ++I   +E++  SP+   I +  + +EI  +   G+E++ T+
Sbjct: 2731 NLTLNSDNTLSVSFVPQETGEHFVSVKKS--GKHVTGSPFSVMVSGPGPADASKVKVTGDGLRKGVTGEPARFTVNTRDAGYGGLGLSIEGPSKAEINCVDNEDGTCSVDYLPTEPGKYTINIKFADEHVPGSPFKANIRRPGE-EEIVAMSEDGVESEPTQ 2889          

HSP 8 Score: 60.4622 bits (145), Expect = 1.035e-8
Identity = 39/135 (28.89%), Postives = 65/135 (48.15%), Query Frame = 3
Query: 4860 LDSISVKTESGDLSQIPYEVHVI----------GKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA---DDVNRRILHKHVKPDIC 5225
            + +++V      + + P++V++           G  L KGFV+  N F + T G   G L + IEGPS+A+I  +D   G   V Y    PG+Y+  I +    IP SPF+  ++   D    ++    ++P IC
Sbjct: 1168 MHTVAVHFNDKPIPKSPFKVNICSTNTSKCRAYGPGLEKGFVDQRNDFKIETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADKHIPGSPFKARISHPFDPSKVKVEGPGIEPGIC 1302          

HSP 9 Score: 60.077 bits (144), Expect = 1.277e-8
Identity = 47/171 (27.49%), Postives = 83/171 (48.54%), Query Frame = 3
Query: 1041 SKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG--------LENKNTKSFIIDS 1523
            ++      S  P   G  D+ +K  +    I   PF+V V LP   P+   +YGPGL  +  + P  F ++T G+    +  ++EGPS+ K+ C + G+G+  ++Y  +  G Y + I   +E+I  SP++    K+ +  +  KVK  G        L +K  + F +D+
Sbjct: 1535 NQDGSFGVSYTPFEEGIHDLAVKFGD--DHIPGSPFKVDV-LPVTDPSKCKAYGPGLQHAQLNKPADFTVETKGAGAGGLSLAIEGPSEAKLTCQDNGDGTCSVSYIPVEEGDYDIHIKFADEHIPGSPFT---AKAGRPVDPSKVKCHGPGVDRVNPLFSKTPQRFTVDT 1699          

HSP 10 Score: 58.151 bits (139), Expect = 4.279e-8
Identity = 41/119 (34.45%), Postives = 64/119 (53.78%), Query Frame = 3
Query: 1131 ILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQ-IGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIG 1484
            I   PF+V +   N      +YGPGL     D    F ++T G+ +  +G ++EGPS+ KI+C + G+GS  + Y    PG Y ++I+  +++I  SP+   I  S+  D   KVKV G
Sbjct: 1180 IPKSPFKVNICSTNTSKC-RAYGPGLEKGFVDQRNDFKIETKGAGEGGLGLTIEGPSEAKIDCIDNGDGSCDVHYWPNEPGDYMVNILYADKHIPGSPFKARI--SHPFDP-SKVKVEG 1294          

HSP 11 Score: 57.3806 bits (137), Expect = 7.141e-8
Identity = 34/84 (40.48%), Postives = 41/84 (48.81%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF 5159
            P  V   GK L +G      +F V T    PG L++ +EGPSKAEI   D   G   V+Y    PGEY   + F    IP SPF
Sbjct: 2061 PGAVKAFGKGLERGLAKEPCEFTVVTRDAGPGGLSLAVEGPSKAEIKCQDNGDGSCNVTYVPDEPGEYNINVKFADKHIPGSPF 2144          

HSP 12 Score: 55.4546 bits (132), Expect = 3.404e-7
Identity = 73/274 (26.64%), Postives = 107/274 (39.05%), Query Frame = 3
Query: 5073 YIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLR--DPN 5885
            Y   Y     G Y   +SF     P SPFR+ VA   N              + + Q  G  T+I           S      L   VT P G  +   I     T N+DG       + GV    F   + D       VK  + H  +  +    DV + + +P           AYG GLQ A +N+   F +      E+       L + I+GPS+ +++C ++ +G     YIP+  G Y I I ++++ HIPGSPF     R  DP+
Sbjct: 1445 YKCDYIAPAEGPYNVKVSFGDKPAPGSPFRVNVAKAGN------------AGKCKAQGDGLETAIINQLAEFDVDCSQAGEGQLMASVTNPSGAHTDTLI-----TDNQDG-------SFGVSYTPFEEGIHD-----LAVKFGDDH--IPGSPFKVDV-LPVTDP-------SKCKAYGPGLQHAQLNKPADFTV------ETKGAGAGGLSLAIEGPSEAKLTCQDNGDGTCSVSYIPVEEGDYDIHIKFADE-HIPGSPFTAKAGRPVDPS 1672          

HSP 13 Score: 54.6842 bits (130), Expect = 4.884e-7
Identity = 36/128 (28.12%), Postives = 61/128 (47.66%), Query Frame = 3
Query: 1059 SFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVI 1436
            +   +P   G   + +K +E    I   PF++ V      P  V +YGPGL    A     F ++        +  S++GP+K K+ C    +G+  +TY  ++ G Y +SI    ++I DSPY++ I
Sbjct: 3139 AIRFVPKEFGDHLVNVKFDE--THIPGSPFKIRVGGGGAHPEKVKAYGPGLSSGHAGKSAEFTVNALEAGSGALALSVDGPAKVKMNCTENQDGTYQVTYYPVVAGEYTISIKFAGQHIPDSPYNVTI 3264          

HSP 14 Score: 52.7582 bits (125), Expect = 2.087e-6
Identity = 22/70 (31.43%), Postives = 36/70 (51.43%), Query Frame = 3
Query: 2064 SIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSP 2273
            S+GF +EGP + +++C    DG+  + + P+  GKY + VT     I  SPF + +S   D      + P
Sbjct: 1037 SLGFAIEGPAQAEIKCVDVGDGKCEVTYYPLVPGKYAVHVTCGDVDIKNSPFMVPISPAGDASKVYAKGP 1106          
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO45254 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE6])

HSP 1 Score: 114.775 bits (286), Expect = 2.295e-25
Identity = 71/220 (32.27%), Postives = 119/220 (54.09%), Query Frame = 3
Query:  102 KIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFL---GENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDK-AIMTYVSQFS 749
            +I+K  FT W N +++     I DL     +G  +V L+E +++KK +  + + +  Q ++      L  L  +G++L NI+  DI++G++K I  L+W LI HY I +     G+       K+ L  L        I N+++ WNSGIA+  ++N CD  L TD  + N  N++ N + AM+ A   F IPQ+L P E+  +   D+ ++MTY+S F+
Sbjct:   40 EIQKNTFTNWCNEQIRESGIVITDLAIAFNDGVTIVYLVESVAEKKCKNCKMNPKFVQDKLENTTQALKLLENDGIQLVNIDNQDIVNGNLKLIMGLIWRLILHYQISSSASASGKQLLLLWLKNALPELK-------IGNVTTDWNSGIALAALINFCDPRLMTDWREMNPDNSIANVKKAMKCAEDNFRIPQILSP-ELFASPYVDELSMMTYLSFFT 251          

HSP 2 Score: 51.6026 bits (122), Expect = 4.429e-6
Identity = 62/254 (24.41%), Postives = 107/254 (42.13%), Query Frame = 3
Query: 4968 KFVVHTSGKIPGNLAICIEGPSKA-EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF-INVFASTIGVYNIDF-YN--------FLGDKIGPSWKVKI-ENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVN-----RKNHFFIFLWNYS 5678
            KF V T+    G LAI  +GP+    +       G Y VSY    PG+YV   +FN  D+P SP R +VA D ++ + H     D   +VE+ + G           +  H ++   L ++       G +   P++ +  + + D + +      +G++ I   YN        FL  K+  + KV++ +N+H S R   +  +VD+ +  P    E   +    G  ++    +       NH   F+ N S
Sbjct:  567 KFEVDTTSAGLGELAIKCKGPTGGIPVDVRATARGKYQVSYLPNTPGDYVTHCTFNGEDVPESPLR-SVAGDPDKIVAHG----DGLYQVEVGSPGEFF--------ITLHGAARGGLEVSG-----DGPNGHFPVELVESSRDNDTYTVRFMPQGVGIHKIHIRYNGRPVRGSPFL-VKVSDASKVRLSKNVHTSGRGHVIRHEVDVPLEVPREAGEGELSATCVGPDMESVATSVTKERDGNHHIRFMPNRS 801          
BLAST of Filamin A vs. Ensembl Nematostella
Match: ALPHA-ACTININ (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4X0])

HSP 1 Score: 94.3597 bits (233), Expect = 3.285e-19
Identity = 71/258 (27.52%), Postives = 133/258 (51.55%), Query Frame = 3
Query:   99 HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLE-----KIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGY---FIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATD-KAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVID-DGGNTSMM 842
             + +KK FT W N  L+   K I +++ DL +G +L++L+EI+S ++L      K+RF       RI  +N  L F+  +G++L ++   +I+DG++K    ++W +I  ++I+    E++F + G   L W   K   Y    + N ++++  G+A   +++    DL  D       + L N   A + A Q   IP++L P ++++T   D +A+MTYVS +       ++ + D   K +  V++ +  N  MM
Sbjct:   26 ERQQKKTFTAWCNSHLRKTGKQIGEIEEDLRDGVLLLQLLEIISGERLPHPERGKLRF------HRIANVNKALDFVAGKGVKLVSVGAEEIVDGNLKMTLGMIWTIILRFAIQDIAIEDSFAKDG--LLLWCQRKTAPYKNVSVKNFTTSFKDGLAFCALIHRHRPDLI-DYDSLRKEDPLYNLNKAFDVAEQYLDIPRMLDPEDMVETERPDERAVMTYVSSYYHAFT--SSQQADTAAKRIGKVLNINRDNERMM 272          
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0])

HSP 1 Score: 93.2041 bits (230), Expect = 9.506e-19
Identity = 74/237 (31.22%), Postives = 120/237 (50.63%), Query Frame = 3
Query:   63 EMKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSV---LIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIK--TFLGENNFDEIGK-SFLNWLNSKLDGYF---IDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF 746
            E  R K    +  +++KK FT+WIN  L+     + +L  DL +G  L+ L+E+LS +KL K    ++ R  RI  L +V   L+FL+ + + L+N+   DI+DG+ K    L+W +I  + I+  T  GE       K + L W  SK  GY    I N +++W  G+A   I++    DL  +  K   ++A  N + A E A     I  LL   ++      +K+I+TYV+ +
Sbjct:   11 ERSRIKVLADERERVQKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPK---PSKGRM-RIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITIEGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDL-IEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAY 242          
BLAST of Filamin A vs. Ensembl Nematostella
Match: EDO30309 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T157])

HSP 1 Score: 85.1149 bits (209), Expect = 3.427e-18
Identity = 64/221 (28.96%), Postives = 115/221 (52.04%), Query Frame = 3
Query:  111 KKVFTRWINHKLKYHNK---FIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGY--FIDNLSSAWNSGIAIGLIVNTCDRDL--CTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTY 734
            +K FT+W+N KL  H      I+D+  DL +G +L+ L+E+L++KKL+K +     R  +I  +   L+ L    ++L  I   DI+DG  + I  LLW +I  + ++  + +    E  KSF      L W   +LDGY   I++ SS+W +G+A   I+++ + +    T+V +  ++  L   + A ++A   F +P++L   ++       K I+ Y
Sbjct:   13 RKAFTKWVNSKLADHPTEPCTIKDVVTDLQDGRMLLNLLEVLTRKKLKKEK--GNLRVHKINNVERALVLLDECKIKLVGINGFDIVDGKHRVILGLLWSIILRFQVEEVMQQEVNAESAKSFTIEKRLLEWCRERLDGYDVEINDFSSSWQNGLAFSAILHSYNPEAFDYTEVKQMGTTERL---EHAFQSAEDGFDVPRILDASDVNVPRPDKKLIILY 228          
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476])

HSP 1 Score: 160.999 bits (406), Expect = 8.982e-39
Identity = 135/488 (27.66%), Postives = 227/488 (46.52%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNK-PFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454
            EM  T+ ++ +     KI++  FTRW N  LK  NK I DLQ D  +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + ++  DE  K        L W+ +K+    I+N +  W  G A+G +V+ C   LC D + W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF     +     R    +    K     I+  GN  +  A  + + +                 G V + ++ P   K+ AK  V    DK G                 + +  P + G   +   K  ++ + ++K P+ V V+     P+ V + GPGL   G+VA+ P  F + T G+ +  I   +  P   K    +   N G+     TY  +L G + + I+   + I  SP+ + I ++  V
Sbjct:   27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRGT---------------YTVTYTPKVEGVHKV---KVLFAGQDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481          

HSP 2 Score: 104.76 bits (260), Expect = 9.443e-22
Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G     ++F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + +A   D  RR+       K +K +  +   +Q  G    +          V +P      C+V+E     S                I       GV++ID              VK    H  GS          ++++ +P ++ +    + A+G GLQ  T    + F +   N          +L V IDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2279 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2556          

HSP 3 Score: 86.6557 bits (213), Expect = 2.927e-16
Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN +  F V T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF  +IT  D + R   L+     D+  ++ E      + SI+    N       P +L     +   H G SF P  + +   +  KDG        I V N  F   +G  +IG + +VK                                   A+G GL +A       FF+   N           L ++I+GPSKV I+C +  +G     Y P   G Y + I ++ K HIPGSPF + V
Sbjct: 1851 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2118          

HSP 4 Score: 74.7146 bits (182), Expect = 1.087e-12
Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586
            N+ V+    +G    C    + +K N  S   IP   G + + +  N     +L  PF V   +P     + ++GPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y    PG Y ++I+  E++I  SP+   I  +  +D IK V    GLE        +F +D SR    E+   +E   + GV +
Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246          

HSP 5 Score: 67.781 bits (164), Expect = 1.341e-10
Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526
            G +++ +K PT  ++      V+  D    VY+C                 P+ +G + + I        I   PF V V        + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +  N   E  K    GL+      NK T+ F ID+R
Sbjct:  553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741          

HSP 6 Score: 64.6994 bits (156), Expect = 1.243e-9
Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            ++  ++ + G + + Y    PG+YV  I F   +IP SPF++   ++         V P               ++ P+ + + F V  +P+   +   V  P G ++   I     T NKDG I +    +  G++ +D              +K +  H  +  + L   VD   +N  +V        AYG GL    VN+   F +   N  E        L + ++GPSK +I+C ++ +G     Y+P   G Y I + + NK HIPGSPF   +  D
Sbjct: 1713 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1938          

HSP 7 Score: 60.8474 bits (146), Expect = 1.860e-8
Identity = 95/373 (25.47%), Postives = 148/373 (39.68%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV+ +   ++  P+++ V    IG     KA  KG +  +     +F V T     G LA+ IEGPSK +I+  D + G   V+Y  T PG Y   I F +  IP SPF + V  +   RI     +    S +         ++K  G N    VS+ E L    F    H  +      ++SKT   +    + V  ST +G     F +  GD +G         +       + S  +  Q I P  VN  Y+                       + A G GL++      + F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 2005 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGE--GRIKESITRKRQASSLASVGSTCGLNLKIPG-NWFQMVSAQERLT-RTFTRSSHTYTRTER-TEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2365          

HSP 8 Score: 58.5362 bits (140), Expect = 1.077e-7
Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             L  S  P   G  ++ ++K+   + + N PF++ V      +   + ++G GL  +       F +DT N     +  S+EGPSK  I C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 1990 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2126          

HSP 9 Score: 55.8398 bits (133), Expect = 6.554e-7
Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3
Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + + GPGL   VA  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  DE +++ V  L+ K+ K
Sbjct: 2281 VRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2386          

HSP 10 Score: 55.0694 bits (131), Expect = 1.141e-6
Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            S++ +   IP  +G   I +K N     I   PF V V  P     P +V ++GPGL G     P  F++ T N     +  +++GPSK K++C     G   ITY+ + PG Y ++I     ++I  SP+
Sbjct: 2425 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2552          
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476])

HSP 1 Score: 160.614 bits (405), Expect = 1.006e-38
Identity = 136/487 (27.93%), Postives = 225/487 (46.20%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454
            EM  T+ ++ +     KI++  FTRW N  LK  NK I DLQ D  +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + ++  DE  K        L W+ +K+    I+N +  W  G A+G +V+ C   LC D + W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF     +     R    +    K     I+  GN  +  A  + + +                 G V + ++ P   K+ AK  V    DK G  Y  T    ++   E    +  + +G             +I   P+ V V+     P+ V + GPGL   G+VA+ P  F + T G+ +  I   +  P   K    +   N G+     TY  +L G + + I+   + I  SP+ + I ++  V
Sbjct:   27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481          

HSP 2 Score: 104.375 bits (259), Expect = 1.197e-21
Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G     ++F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + +A   D  RR+       K +K +  +   +Q  G    +          V +P      C+V+E     S                I       GV++ID              VK    H  GS          ++++ +P ++ +    + A+G GLQ  T    + F +   N          +L V IDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2279 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2556          

HSP 3 Score: 86.2705 bits (212), Expect = 3.587e-16
Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN +  F V T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF  +IT  D + R   L+     D+  ++ E      + SI+    N       P +L     +   H G SF P  + +   +  KDG        I V N  F   +G  +IG + +VK                                   A+G GL +A       FF+   N           L ++I+GPSKV I+C +  +G     Y P   G Y + I ++ K HIPGSPF + V
Sbjct: 1851 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2118          

HSP 4 Score: 74.7146 bits (182), Expect = 1.245e-12
Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586
            N+ V+    +G    C    + +K N  S   IP   G + + +  N     +L  PF V   +P     + ++GPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y    PG Y ++I+  E++I  SP+   I  +  +D IK V    GLE        +F +D SR    E+   +E   + GV +
Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246          

HSP 5 Score: 67.781 bits (164), Expect = 1.498e-10
Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526
            G +++ +K PT  ++      V+  D    VY+C                 P+ +G + + I        I   PF V V        + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +  N   E  K    GL+      NK T+ F ID+R
Sbjct:  553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741          

HSP 6 Score: 64.6994 bits (156), Expect = 1.448e-9
Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            ++  ++ + G + + Y    PG+YV  I F   +IP SPF++   ++         V P               ++ P+ + + F V  +P+   +   V  P G ++   I     T NKDG I +    +  G++ +D              +K +  H  +  + L   VD   +N  +V        AYG GL    VN+   F +   N  E        L + ++GPSK +I+C ++ +G     Y+P   G Y I + + NK HIPGSPF   +  D
Sbjct: 1713 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1938          

HSP 7 Score: 60.4622 bits (145), Expect = 2.375e-8
Identity = 95/373 (25.47%), Postives = 148/373 (39.68%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFAST-IGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV+ +   ++  P+++ V    IG     KA  KG +  +     +F V T     G LA+ IEGPSK +I+  D + G   V+Y  T PG Y   I F +  IP SPF + V  +   RI     +    S +         ++K  G N    VS+ E L    F    H  +      ++SKT   +    + V  ST +G     F +  GD +G         +       + S  +  Q I P  VN  Y+                       + A G GL++      + F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 2005 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGE--GRIKESITRKRQASSLASVGSTCGLNLKIPG-NWFQMVSAQERLT-RTFTRSSHTYTRTER-TEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2365          

HSP 8 Score: 58.151 bits (139), Expect = 1.153e-7
Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             L  S  P   G  ++ ++K+   + + N PF++ V      +   + ++G GL  +       F +DT N     +  S+EGPSK  I C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 1990 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2126          

HSP 9 Score: 55.8398 bits (133), Expect = 7.255e-7
Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3
Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            + + GPGL   VA  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  DE +++ V  L+ K+ K
Sbjct: 2281 VRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2386          

HSP 10 Score: 55.0694 bits (131), Expect = 1.232e-6
Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            S++ +   IP  +G   I +K N     I   PF V V  P     P +V ++GPGL G     P  F++ T N     +  +++GPSK K++C     G   ITY+ + PG Y ++I     ++I  SP+
Sbjct: 2425 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2552          
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476])

HSP 1 Score: 160.614 bits (405), Expect = 1.065e-38
Identity = 136/487 (27.93%), Postives = 225/487 (46.20%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454
            EM  T+ ++ +     KI++  FTRW N  LK  NK I DLQ D  +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + ++  DE  K        L W+ +K+    I+N +  W  G A+G +V+ C   LC D + W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF     +     R    +    K     I+  GN  +  A  + + +                 G V + ++ P   K+ AK  V    DK G  Y  T    ++   E    +  + +G             +I   P+ V V+     P+ V + GPGL   G+VA+ P  F + T G+ +  I   +  P   K    +   N G+     TY  +L G + + I+   + I  SP+ + I ++  V
Sbjct:   27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481          

HSP 2 Score: 104.375 bits (259), Expect = 1.318e-21
Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G     ++F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + +A   D  RR+       K +K +  +   +Q  G    +          V +P      C+V+E     S                I       GV++ID              VK    H  GS          ++++ +P ++ +    + A+G GLQ  T    + F +   N          +L V IDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2329 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2606          

HSP 3 Score: 86.2705 bits (212), Expect = 3.752e-16
Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN +  F V T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF  +IT  D + R   L+     D+  ++ E      + SI+    N       P +L     +   H G SF P  + +   +  KDG        I V N  F   +G  +IG + +VK                                   A+G GL +A       FF+   N           L ++I+GPSKV I+C +  +G     Y P   G Y + I ++ K HIPGSPF + V
Sbjct: 1873 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2140          

HSP 4 Score: 74.3294 bits (181), Expect = 1.440e-12
Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586
            N+ V+    +G    C    + +K N  S   IP   G + + +  N     +L  PF V   +P     + ++GPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y    PG Y ++I+  E++I  SP+   I  +  +D IK V    GLE        +F +D SR    E+   +E   + GV +
Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246          

HSP 5 Score: 67.781 bits (164), Expect = 1.578e-10
Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526
            G +++ +K PT  ++      V+  D    VY+C                 P+ +G + + I        I   PF V V        + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +  N   E  K    GL+      NK T+ F ID+R
Sbjct:  553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741          

HSP 6 Score: 64.3142 bits (155), Expect = 1.525e-9
Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            ++  ++ + G + + Y    PG+YV  I F   +IP SPF++   ++         V P               ++ P+ + + F V  +P+   +   V  P G ++   I     T NKDG I +    +  G++ +D              +K +  H  +  + L   VD   +N  +V        AYG GL    VN+   F +   N  E        L + ++GPSK +I+C ++ +G     Y+P   G Y I + + NK HIPGSPF   +  D
Sbjct: 1735 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1960          

HSP 7 Score: 58.5362 bits (140), Expect = 9.760e-8
Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV+ +   ++  P+++ V    IG     KA  KG +  +     +F V T     G LA+ IEGPSK +I+  D + G   V+Y  T PG Y   I F +  IP SPF + V  +  +   I  K     + S      + ++  GN   +    + L   F  SS          +++  GG +   ++    T    G   F +VF   +G  ++  +  L  +                PS K V  + + G   S+T S     Q I P  VN  Y+                       + A G GL++      + F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 2027 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2415          

HSP 8 Score: 58.151 bits (139), Expect = 1.235e-7
Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             L  S  P   G  ++ ++K+   + + N PF++ V      +   + ++G GL  +       F +DT N     +  S+EGPSK  I C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 2012 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2148          

HSP 9 Score: 56.6102 bits (135), Expect = 3.619e-7
Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L  G  N  N+F V T G   G L + IEG S+A+IS  D K G   V Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1396 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1488          

HSP 10 Score: 56.6102 bits (135), Expect = 4.210e-7
Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            S+  S   IP   G   + +K       +   PF+  V    +     + + GPGL   VA  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  DE +++ V  L+ K+ K
Sbjct: 2285 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2436          

HSP 11 Score: 54.6842 bits (130), Expect = 1.287e-6
Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            S++ +   IP  +G   I +K N     I   PF V V  P     P +V ++GPGL G     P  F++ T N     +  +++GPSK K++C     G   ITY+ + PG Y ++I     ++I  SP+
Sbjct: 2475 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2602          

HSP 12 Score: 53.1434 bits (126), Expect = 3.708e-6
Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532
            K    S   +P   G +D+ I  N     I   PFRV V  P     +   GPGL  G  A  P  F +D T      +   + GP+ T   +   N G+G+  + Y+    G Y +S+  +++ +  SP+ ++    +   ++ +    GL+ K   +     F ID+R++
Sbjct: 1447 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1615          
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476])

HSP 1 Score: 160.229 bits (404), Expect = 1.203e-38
Identity = 135/487 (27.72%), Postives = 223/487 (45.79%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKV 1454
            EM  T+ ++ +     KI++  FTRW N  LK  NK I DLQ D  +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + ++  DE  K        L W+ +K+    I+N +  W  G A+G +V+ C   LC D + W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF     +     R    +    K     I+  GN  +  A  + + +                 G V + ++ P   K+ AK  V    DK G                 + +  P + G     +K      +I   P+ V V+     P+ V + GPGL   G+VA+ P  F + T G+ +  I   +  P   K    +   N G+     TY  +L G + + I+   + I  SP+ + I ++  V
Sbjct:   27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRGT---------------YTVTYTPKVEGVHK--VKVLFAGQDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEAPSV 481          

HSP 2 Score: 104.375 bits (259), Expect = 1.209e-21
Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G     ++F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + +A   D  RR+       K +K +  +   +Q  G    +          V +P      C+V+E     S                I       GV++ID              VK    H  GS          ++++ +P ++ +    + A+G GLQ  T    + F +   N          +L V IDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2299 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2576          

HSP 3 Score: 86.2705 bits (212), Expect = 3.622e-16
Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN +  F V T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF  +IT  D + R   L+     D+  ++ E      + SI+    N       P +L     +   H G SF P  + +   +  KDG        I V N  F   +G  +IG + +VK                                   A+G GL +A       FF+   N           L ++I+GPSKV I+C +  +G     Y P   G Y + I ++ K HIPGSPF + V
Sbjct: 1843 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2110          

HSP 4 Score: 74.3294 bits (181), Expect = 1.450e-12
Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586
            N+ V+    +G    C    + +K N  S   IP   G + + +  N     +L  PF V   +P     + ++GPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y    PG Y ++I+  E++I  SP+   I  +  +D IK V    GLE        +F +D SR    E+   +E   + GV +
Sbjct: 1044 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1246          

HSP 5 Score: 67.781 bits (164), Expect = 1.512e-10
Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526
            G +++ +K PT  ++      V+  D    VY+C                 P+ +G + + I        I   PF V V        + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +  N   E  K    GL+      NK T+ F ID+R
Sbjct:  553 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 741          

HSP 6 Score: 64.3142 bits (155), Expect = 1.833e-9
Identity = 82/313 (26.20%), Postives = 124/313 (39.62%), Query Frame = 3
Query: 5028 PSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV--ADDVNRRILHKHVKPDICSEVEMQNKGNSTSI----KPVGKNLIF-HVSSPEILNLN------------CFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFY-------NFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            P  A I   D + G Y VSY     G Y   I +   +IP+SP+RI      D ++ +L   V     S ++       T I    K  GK  +   V +P+ + L+             + T P  G     I+   +   K  F  V A+   V   D         NFL        + K  N+    S+R T+   +   Q     + + +   + AYG GL    VN+   F +   N  E        L + ++GPSK +I+C ++ +G     Y+P   G Y I + + NK HIPGSPF   +  D
Sbjct: 1631 PKNATIQ--DNRDGTYTVSYVPDSTGPYTITIKYGGDEIPYSPYRIQSLPTGDASKCLLTVSVGGHGMSSLQKLQTSEDTVITVDAKAAGKGKVTCKVLTPQGMELDMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPF-QVMATNEPVVPRDTVDPLFRPVNFLVPFTPQCRQGKPTNLQREASMRWTSNMMETTFQFYVDAVNSGV---VTAYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1930          

HSP 7 Score: 58.5362 bits (140), Expect = 8.964e-8
Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV+ +   ++  P+++ V    IG     KA  KG +  +     +F V T     G LA+ IEGPSK +I+  D + G   V+Y  T PG Y   I F +  IP SPF + V  +  +   I  K     + S      + ++  GN   +    + L   F  SS          +++  GG +   ++    T    G   F +VF   +G  ++  +  L  +                PS K V  + + G   S+T S     Q I P  VN  Y+                       + A G GL++      + F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 1997 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2385          

HSP 8 Score: 58.151 bits (139), Expect = 1.213e-7
Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             L  S  P   G  ++ ++K+   + + N PF++ V      +   + ++G GL  +       F +DT N     +  S+EGPSK  I C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 1982 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2118          

HSP 9 Score: 56.6102 bits (135), Expect = 3.525e-7
Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L  G  N  N+F V T G   G L + IEG S+A+IS  D K G   V Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1396 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1488          

HSP 10 Score: 56.6102 bits (135), Expect = 4.032e-7
Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            S+  S   IP   G   + +K       +   PF+  V    +     + + GPGL   VA  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  DE +++ V  L+ K+ K
Sbjct: 2255 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2406          

HSP 11 Score: 55.0694 bits (131), Expect = 1.243e-6
Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            S++ +   IP  +G   I +K N     I   PF V V  P     P +V ++GPGL G     P  F++ T N     +  +++GPSK K++C     G   ITY+ + PG Y ++I     ++I  SP+
Sbjct: 2445 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2572          

HSP 12 Score: 53.1434 bits (126), Expect = 3.863e-6
Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532
            K    S   +P   G +D+ I  N     I   PFRV V  P     +   GPGL  G  A  P  F +D T      +   + GP+ T   +   N G+G+  + Y+    G Y +S+  +++ +  SP+ ++    +   ++ +    GL+ K   +     F ID+R++
Sbjct: 1447 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1615          
BLAST of Filamin A vs. Ensembl Medaka
Match: flnc (filamin C [Source:NCBI gene;Acc:101165476])

HSP 1 Score: 160.229 bits (404), Expect = 1.459e-38
Identity = 135/484 (27.89%), Postives = 224/484 (46.28%), Query Frame = 3
Query:   63 EMKRTKSEILKS---HKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQD-RQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSF------LNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQE-----RNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIV-SYGPGL--YGSVADCPGVFILDTNGS-DQQIGFSMEGPSKTK----IECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS 1445
            EM  T+ ++ +     KI++  FTRW N  LK  NK I DLQ D  +G  L+ L+E+LSQKK+ +   +  + RQ ++  ++  L FL  E ++L +I+   I+DG++K I  L+W LI HYSI   + ++  DE  K        L W+ +K+    I+N +  W  G A+G +V+ C   LC D + W+ +  + NA+ AM+ A     +PQ++ P EI+D    + ++MTY+SQF     +     R    +    K     I+  GN  +  A  + + +                 G V + ++ P   K+ AK  V    DK G  Y  T    ++   E    +  + +G             +I   P+ V V+     P+ V + GPGL   G+VA+ P  F + T G+ +  I   +  P   K    +   N G+     TY  +L G + + I+   + I  SP+ + I ++
Sbjct:   27 EMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKTITDLQKDFSDGLKLISLLEVLSQKKMYRKHHTRPNFRQMKLENVSVALEFLDREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDEDDEETKKLTPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWVDWDPNQPVQNAKEAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPLRPKQLFPDKVKAYGPGIEPHGNKVLHPAVFTVETLE-------------AGSGEVLVFVEDPEGHKEEAK--VKPNKDKRG-TYTVT----YTPKVEGVHKVKVLFAG------------QDIDKSPYTVNVDKDMGDPSKVHARGPGLEATGNVANKPTYFDIYTAGAGNGDISVVIVDPRGKKDTVELILENKGDSVFRCTYHPVLEGPHTIHILFAGQEIPRSPFHVNIAEA 478          

HSP 2 Score: 104.375 bits (259), Expect = 1.303e-21
Identity = 97/329 (29.48%), Postives = 138/329 (41.95%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVA--DDVNRRIL-----HKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L +G     ++F + T     G L+I +EGPSKAEI+F D+K G   VSY V  PG+Y  +I FN   IP SPF + +A   D  RR+       K +K +  +   +Q  G    +          V +P      C+V+E     S                I       GV++ID              VK    H  GS          ++++ +P ++ +    + A+G GLQ  T    + F +   N          +L V IDGPSKV++ C E   GY   Y P+  G Y I I Y    HI GSPFK  V
Sbjct: 2290 HKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLSDEARRLTVTSLQEKDLKVNQEASFMVQRNGPRGVVDA-------KVHTPSGSTEECYVSELDSDKS---------------AIRFIPRENGVHSID--------------VKFNGCHIPGS--------PFNVRVGDPGLIGDPGM-VTAHGPGLQGGTTGIPSEFVVKTCNAGSG------TLSVNIDGPSKVKMDCRECPEGYRITYTPMAPGNYLITIKYGGPQHIVGSPFKAKV 2567          

HSP 3 Score: 86.2705 bits (212), Expect = 3.650e-16
Identity = 96/326 (29.45%), Postives = 134/326 (41.10%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPF--RITVADDVNRRI-LHKHVKPDICSEV-EMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHP--IKKMSKTSNKDGFINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            V   G  L  G VN +  F V T     G L++ +EGPSKAEI+  D K G   VSY  T PG+Y   + F+   IP SPF  +IT  D + R   L+     D+  ++ E      + SI+    N       P +L     +   H G SF P  + +   +  KDG        I V N  F   +G  +IG + +VK                                   A+G GL +A       FF+   N           L ++I+GPSKV I+C +  +G     Y P   G Y + I ++ K HIPGSPF + V
Sbjct: 1834 VTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNVGTATDVSLKITETDLSCLTASIRAPSGN-----EEPCLLKR---LPNRHLGISFTPKEVGEHEVSVRKDG--------IHVANSPFKIMVGQSEIGEASRVK-----------------------------------AFGKGLIEAHTFEMAEFFVDTRNAGYG------GLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEK-HIPGSPFAVKV 2101          

HSP 4 Score: 74.7146 bits (182), Expect = 1.155e-12
Identity = 60/210 (28.57%), Postives = 98/210 (46.67%), Query Frame = 3
Query:  975 NLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGF-SMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV-IGLENKNT---KSFIID-SRNSTFEMPPDVECFDKLGVSS 1586
            N+ V+    +G    C    + +K N  S   IP   G + + +  N     +L  PF V   +P     + ++GPGL G +   P  F +DT G+       ++EGP + KIEC + G+G+  ++Y    PG Y ++I+  E++I  SP+   I  +  +D IK V    GLE        +F +D SR    E+   +E   + GV +
Sbjct: 1005 NVGVKMTSPSGRPIPCKLESDKAKGNH-SVKYIPPEEGQYKVDV--NYDGNPVLGSPFGVEAVMPADPSKVRAFGPGLQGGIVGKPAPFTIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEPGEYAINILFAEQHISGSPFKAAIRPA--LDPIKVVASGPGLERAKAGEPATFTVDCSRAGDAEL--TIEIVSETGVKA 1207          

HSP 5 Score: 68.1662 bits (165), Expect = 1.184e-10
Identity = 59/211 (27.96%), Postives = 98/211 (46.45%), Query Frame = 3
Query:  921 GRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKS--NKVDEIKKVKVIGLE------NKNTKSFIIDSR 1526
            G +++ +K PT  ++      V+  D    VY+C                 P+ +G + + I        I   PF V V        + ++GPGL   +      F+++  G++   +GFS+EGPS+ KIEC + G+GS  + Y    PG Y + ++ ++E+I DSP+   I+ +  N   E  K    GL+      NK T+ F ID+R
Sbjct:  514 GTLNVSVKGPTGAEE-----QVKVRDAGNGVYEC--------------EYYPLKAGKYTVSITWG--GQPIPRSPFEVEVGEEAGFQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVHYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAVNNVFPEKVKAYGPGLQPTGVIVNKPTE-FTIDAR 702          

HSP 6 Score: 64.6994 bits (156), Expect = 1.460e-9
Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 5040 EISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVS-SPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVF--ASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGY-IFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRD 5879
            ++  ++ + G + + Y    PG+YV  I F   +IP SPF++   ++         V P               ++ P+ + + F V  +P+   +   V  P G ++   I     T NKDG I +    +  G++ +D              +K +  H  +  + L   VD   +N  +V        AYG GL    VN+   F +   N  E        L + ++GPSK +I+C ++ +G     Y+P   G Y I + + NK HIPGSPF   +  D
Sbjct: 1696 DMDVVENRDGTFDIYYTAPEPGKYVITIRFGGQNIPKSPFQVMATNE--------PVVP-------------RDTVDPLFRPVNFLVPFTPQQGEITGEVKMPSGKTARPHI-----TDNKDGTITIKYQPTERGLHEMD--------------IKYDGNH--IPGSPLQFYVDA--VNSGVVT-------AYGPGLSYGMVNKSATFTVVTKNAGEG------GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNK-HIPGSPFTAKITGD 1921          

HSP 7 Score: 58.5362 bits (140), Expect = 9.037e-8
Identity = 97/398 (24.37%), Postives = 156/398 (39.20%), Query Frame = 3
Query: 4869 ISVKTESGDLSQIPYEVHV----IG-----KALCKGFVNFNN----KFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADD--VNRRILHKHVKPDICS-----EVEMQNKGNSTSIKPVGKNL--IFHVSSPEILNLN-CFVTEPHGGSSFHPIKKMSKTSNKDG---FINVFASTIGVYNIDFYNFLGDK--------------IGPSWK-VKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQ----------------------NICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            +SV+ +   ++  P+++ V    IG     KA  KG +  +     +F V T     G LA+ IEGPSK +I+  D + G   V+Y  T PG Y   I F +  IP SPF + V  +  +   I  K     + S      + ++  GN   +    + L   F  SS          +++  GG +   ++    T    G   F +VF   +G  ++  +  L  +                PS K V  + + G   S+T S     Q I P  VN  Y+                       + A G GL++      + F I  W            L + ++GPSK +I+  +  +G     YI    G Y + I ++N+ HIP SPF + +
Sbjct: 1988 VSVRKDGIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKESITRKRQASSLASVGSTCGLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGGGSPFRDVFGDFLGRESLSSFAGLTARPEVESGSQAMTAQVTSPSGKTVDADIVDGG--SSTYSVRFIPQEIGPHTVNVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSI--WTREAG----AGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNE-HIPDSPFIVPI 2376          

HSP 8 Score: 58.5362 bits (140), Expect = 9.424e-8
Identity = 36/139 (25.90%), Postives = 68/139 (48.92%), Query Frame = 3
Query: 1053 ELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLP--NKKPTIVSYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDE 1460
             L  S  P   G  ++ ++K+   + + N PF++ V      +   + ++G GL  +       F +DT N     +  S+EGPSK  I C ++ +G+  +TY    PG Y ++I   E++I  SP+++ +    ++ E
Sbjct: 1973 HLGISFTPKEVGEHEVSVRKD--GIHVANSPFKIMVGQSEIGEASRVKAFGKGLIEAHTFEMAEFFVDTRNAGYGGLALSIEGPSKVDINCEDMEDGTCRVTYCPTEPGSYTVNIKFAEKHIPGSPFAVKVTGEGRIKE 2109          

HSP 9 Score: 56.6102 bits (135), Expect = 3.268e-7
Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT--IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTK 1505
            S+  S   IP   G   + +K       +   PF+  V    +     + + GPGL   VA  P  F I         +  ++EGPSK +I   +  +GS  ++Y    PG Y++SI  N E+I DSP+ + I   +  DE +++ V  L+ K+ K
Sbjct: 2246 SSTYSVRFIPQEIGPHTVNVKYR--GQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGAPSEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVKEPGDYEVSIKFNNEHIPDSPFIVPIATLS--DEARRLTVTSLQEKDLK 2397          

HSP 10 Score: 56.6102 bits (135), Expect = 3.554e-7
Identity = 38/93 (40.86%), Postives = 47/93 (50.54%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVN 5186
            P  V   G  L  G  N  N+F V T G   G L + IEG S+A+IS  D K G   V Y    PG+Y   I++    IP SPFR+ V D V+
Sbjct: 1357 PTRVRAFGPGLEGGITNKPNRFTVETRGAGTGGLGLTIEGASEAKISCKDNKDGSCSVEYVPFTPGDYDVNINYGGQPIPGSPFRVPVKDPVD 1449          

HSP 11 Score: 55.0694 bits (131), Expect = 1.059e-6
Identity = 41/131 (31.30%), Postives = 64/131 (48.85%), Query Frame = 3
Query: 1047 SNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPN--KKPTIV-SYGPGLYGSVADCPGVFILDT-NGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMV-NEENICDSPY 1424
            S++ +   IP  +G   I +K N     I   PF V V  P     P +V ++GPGL G     P  F++ T N     +  +++GPSK K++C     G   ITY+ + PG Y ++I     ++I  SP+
Sbjct: 2436 SDKSAIRFIPRENGVHSIDVKFN--GCHIPGSPFNVRVGDPGLIGDPGMVTAHGPGLQGGTTGIPSEFVVKTCNAGSGTLSVNIDGPSKVKMDCRECPEG-YRITYTPMAPGNYLITIKYGGPQHIVGSPF 2563          

HSP 12 Score: 53.5286 bits (127), Expect = 3.184e-6
Identity = 43/172 (25.00%), Postives = 74/172 (43.02%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILD-TNGSDQQIGFSMEGPSKT--KIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKS-----FIIDSRNS 1532
            K    S   +P   G +D+ I  N     I   PFRV V  P     +   GPGL  G  A  P  F +D T      +   + GP+ T   +   N G+G+  + Y+    G Y +S+  +++ +  SP+ ++    +   ++ +    GL+ K   +     F ID+R++
Sbjct: 1408 KDGSCSVEYVPFTPGDYDVNI--NYGGQPIPGSPFRVPVKDPVDPTKVKCSGPGLGTGVRAHVPQNFTVDCTQAGQAPLDVKLYGPTGTVEPVGVKNNGDGTHTVHYTPAQDGPYTVSVKYSDQEVPHSPFKVMSQPGHDASKV-RASGPGLDIKGVPASLPVEFTIDARDA 1576          

HSP 13 Score: 51.9878 bits (123), Expect = 9.649e-6
Identity = 35/146 (23.97%), Postives = 67/146 (45.89%), Query Frame = 3
Query: 1044 KSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGL-YGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKV 1478
            K   ++    P   G  ++ IK +     I   P +  V+  N    + +YGPGL YG V       ++  N  +  +  ++EGPSK +I C +  +G+  ++Y    PG Y + +  + ++I  SP++  I   + +    ++ V
Sbjct: 1790 KDGTITIKYQPTERGLHEMDIKYD--GNHIPGSPLQFYVDAVNSG-VVTAYGPGLSYGMVNKSATFTVVTKNAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYNIIVKFDNKHIPGSPFTAKITGDDSITRTSQLNV 1932          
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1)

HSP 1 Score: 3724.48 bits (9657), Expect = 0.000e+0
Identity = 1905/1951 (97.64%), Postives = 1905/1951 (97.64%), Query Frame = 3
Query:   66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918
            MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY                                            N  NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ
Sbjct:    1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1907          
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1)

HSP 1 Score: 3715.62 bits (9634), Expect = 0.000e+0
Identity = 1905/1957 (97.34%), Postives = 1905/1957 (97.34%), Query Frame = 3
Query:   66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTD------MKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918
            MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTD      MKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY                                            N  NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ
Sbjct:    1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDCFFNFYMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1913          
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1)

HSP 1 Score: 3704.84 bits (9606), Expect = 0.000e+0
Identity = 1900/1951 (97.39%), Postives = 1900/1951 (97.39%), Query Frame = 3
Query:   66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918
            MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIG     PSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY                                            N  NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ
Sbjct:    1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIG-----PSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1902          
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000080268.1 (SMESG000080268.1)

HSP 1 Score: 3648.98 bits (9461), Expect = 0.000e+0
Identity = 1880/1951 (96.36%), Postives = 1883/1951 (96.51%), Query Frame = 3
Query:   66 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECEXXXXXXXXXXXXXXXGVYKAKIRKLSLFSNKDPITRGNFCGYRXXXXXXXXXXXXXXXXXXXXXLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVXXXXXXXXXXXXXXXXXXXXXXYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 5918
            MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDK     +  +   F+  N L      I   SFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY                                            N  NSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ
Sbjct:    1 MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLVVEAVDK----IQLLQMETFT--NVLG---TEIFQRSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECFDKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHLSANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSLSIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGNFCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLSVVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLSTNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDSLLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVLKSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNAINTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSNYKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNKHSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVVHKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSEKLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANISMLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYVKDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPINKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNHLILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINSTDQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLDSISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEY--------------------------------------------NYRNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFENQ 1898          
BLAST of Filamin A vs. Planmine SMEST
Match: SMESG000064795.1 (SMESG000064795.1)

HSP 1 Score: 189.889 bits (481), Expect = 1.003e-47
Identity = 201/782 (25.70%), Postives = 338/782 (43.22%), Query Frame = 3
Query:  105 IEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVELIEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLR-LEGMELKNIEPVDILDGSVKKIKELLWILIFHYSIKTFLGENNFDEIGKS-------FLNWLNSKLDGYFIDNLSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFMIPQLLKPIEIIDTSATDKAIMTYVSQF--------SGLLQERNNNKYDLTGKCLSSVIDDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKDIAKNLV---VEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPTIVSY-GPGLY--GSVADCPGVFILDT-NGSDQQIGFSMEGPS--KTKI--ECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEI----KKVKVIGLENKNTKSFIIDSRNST--------------------FEMPPD-VECF--------DKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAIDYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAI--------ELSVQDLCVDTINDVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKGECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAGKYELFVTIDGKSIDGSPFSITVSETSD 2246
            I+K  FTRW+N  LK  N+ I DLQ D  +G  L+ LIE+LS+ K          R  ++  +  VL FL   EG++L NI+  DI+D  +K I  L+W LI HYSI   + E    ++ +S        ++W+  ++    + NL++ WN G AIG +V++C   LC D  +W   +AL + + AM+ A Q   +PQL+KP E+ID +  +KA+MTY+SQF        + +  + N NK  + G  + S     G T+                       D    GR +L I I     D A  L+   +E +    N YKCT                P   G++ I ++  E   +I   PF+V ++  +  P+ V   GPG+   G +      FI+ T +    +I   +  PS  K KI  +       S  + Y+A   G++ ++I ++   I +SP+ +++   +    +    + ++  G+   +   F ID++N+                      E+ P+  EC          +L ++ +NI VT   +  F+I         +  F       V G   AI   D+N G+     FS     + K     NQD    I        E +V  LC     D+  +     ++  +E  + S++K +    +K G+ L   +         E  +  I+    I+  +  F   G  E  V   +  + +Y   +QP+T G +++FV+ D +S+  SPF + V++ S+
Sbjct:   17 IQKNTFTRWVNVHLKKANQSINDLQNDFSDGIRLMTLIEVLSEHKFTHANKRTNFRTQKLENVTMVLRFLEEKEGLKLINIDSSDIVDCRLKLILGLVWALILHYSISMPIWEGEDSKVHESKQTPKQRMMSWITGRMPEKHVKNLTTDWNDGTAIGALVDSCAPGLCPDWAEWKPVDALIHTKEAMDTAEQWLNVPQLIKPEEMIDPNVDEKAMMTYLSQFPNAKVNPGAPITSKLNPNKVRVYGPGIESKDLIAGQTAEFTV-------------------DAFSAGRGNLDITI----TDNAGKLIDVKIEEIPDKKNCYKCT--------------YTPPCKGTYTITVRYAE--KDIPRSPFKVIIDKTSGDPSKVKVKGPGIEQNGVIVSTSTYFIISTEDAGTGEISCVVLSPSGDKDKINPKITQESPTSYRVEYTAEETGVHSINIFLSSAQIKNSPFGVMVSPRSNAKLVTVSGRGIQSNGIRVGDKAEFFIDTQNAGNGKLNVKLLSPEKSEESVKIAEINPNYFECLYIPSKPGMYELQINYDNIPVT---RSPFKINVLPTKTSHIAAFGPGLTTGVVG-KAAIFVTDTN-GELGSLGFSIEGPSEAKIECCDNQDGSATICYWPTAPGEYAVHILCDG--EDIPNSPYMANIMPSNEKTDVSKIKVYGPGVQKEGVALNSPN---------EFTIDCIEYKSDIKPEASCFTCSG-NEIPVVISSAGNKKYRCVYQPLTDGNHKVFVSCDNQSVPKSPFKVKVAQPSN 742          

HSP 2 Score: 118.627 bits (296), Expect = 4.963e-26
Identity = 104/328 (31.71%), Postives = 143/328 (43.60%), Query Frame = 3
Query: 4911 YEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILN------LNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFLGDK--IGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            ++V   G  L  G  +  N+F ++T     G L+I IEGPSKAEI F D+K G   V Y VT PGEY+C+I FN   I +SPFRI     VN + +      D  S   + +   +     +GK   F V+ P+         L   +  P        I+ + K      FI       G + I+  + + +K   G  ++V I   H                 +P +V+       A GDGL    V +KNHF +   N           L+VTIDGPSKVQ+   E+  GY F YIP   G Y I + Y    HI GSPF   +
Sbjct: 3024 HKVVASGNGLKLGHTSGPNEFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVKYFVTEPGEYICSIKFNDDHIINSPFRIM----VNEKQM------DFISVASVGDNALAKEWT-IGKPAAFTVNYPQTTTIRSDGKLRATIVGPSRTEEPAIIQNIEKNQYAIRFI---PKESGEHLINVTDEITNKHIPGSPFRVVIGQQHA----------------DPGMVH-------AKGDGLMSGFVGKKNHFIVNTLNSGTG------PLNVTIDGPSKVQLYSQENEEGYEFIYIPSAPGEYQITVKYGGNYHIAGSPFTANI 3308          

HSP 3 Score: 91.2781 bits (225), Expect = 9.685e-18
Identity = 93/338 (27.51%), Postives = 138/338 (40.83%), Query Frame = 3
Query: 4914 EVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEILNLNCFVTEPHGGSSFHPIKKM-------SKTSNKDG--FINVFASTIGVYNIDFYNFLG-DKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYI-FCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDL 5894
            +V   G  L  G      +F + T     G L++ IEGPSKAEI   D + G   V+Y   IPG+Y   I F   +IP SPF   +  +  RR         IC          STS  P+  N +      +I  L   V  P G      +KKM       S T  + G  FINV+ S   +    F   +G ++IG + KV++                                   +G+GL+    N  N F +      ++       L ++I+GPSK +I C ++ +G     Y P   G Y I I Y+N+ H+ GSPF + +  +P++ L
Sbjct: 2651 KVAAYGPGLSHGRTGLPAEFTIVTKDAGAGGLSLAIEGPSKAEIVCKDNENGSCDVTYYPLIPGDYSIIIKFADHNIPGSPFIANIIGEPQRR-------SQICI--------GSTSDVPLKINNL------DISTLTASVRAPSGKEESCILKKMPNDNLGISFTPREVGNHFINVYQSGAHILGSPFKIVVGQNEIGDASKVRV-----------------------------------FGEGLKCGISNEMNSFTV------DTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANE-HVSGSPFAVKITGEPSAKL 2925          

HSP 4 Score: 67.781 bits (164), Expect = 1.088e-10
Identity = 89/338 (26.33%), Postives = 132/338 (39.05%), Query Frame = 3
Query: 4878 KTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKN--LIFHVSSPEILNLNCFVTEPHGGSSFHPIKKMSKTSNKDGF--INVFASTIGVYNIDFYNFLGDKIGPSWKVKIENIH--GSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGDGLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDINGYIFC-YIPIVIGLYFIGITYSNKCHIPGSPFKITV 5870
            + E GD S+    V V G+ L  G  N  N F V T     G L++ IEGPSKAEI   D   G   VSY  + PG Y+  I +    +  SPF + +  + + +++ K     IC +        +  I  VG    L   V      ++   VT  +G +    I  +      DG   I      +G++ +               V+  N+H  GS    T         + P IV+     + A G+GL+    +  N F I+              L + I+GPSK +I   +  +G     Y     G Y   I + N  HI  SPF+I V
Sbjct: 2824 QNEIGDASK----VRVFGEGLKCGISNEMNSFTVDTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANEHVSGSPFAVKITGEPSAKLMEKI----ICRQ-------EAADITQVGSQCELTLKVPGTHHSDMRATVTNLYGTTEVCEIIDLD-----DGHYSIKFIPKEMGLHTV--------------VVQHRNMHIPGSPFQFT---------VGP-IVDGGAHKVVASGNGLKLGHTSGPNEFSIYTREAGAG------GLSIAIEGPSKAEIDFEDRKDGSCGVKYFVTEPGEYICSIKF-NDDHIINSPFRIMV 3110          

HSP 5 Score: 65.0846 bits (157), Expect = 7.758e-10
Identity = 35/79 (44.30%), Postives = 42/79 (53.16%), Query Frame = 3
Query: 4908 PYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDI 5144
            P +V V G+ L  GF N  N F +   G   GNL + IEGPS A+I+  D   G   V Y  TIPG Y   I FN VD+
Sbjct:  937 PSKVLVFGEGLEGGFTNQPNFFTIDLDGAGQGNLGLAIEGPSDAKINCTDNLDGTCTVEYSSTIPGTYDIYIKFNDVDV 1015          

HSP 6 Score: 64.3142 bits (155), Expect = 1.242e-9
Identity = 51/198 (25.76%), Postives = 98/198 (49.49%), Query Frame = 3
Query:  999 KNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCVNLPNKKPT-IVSYGPGLYGSVADCPGVFILDTNGSDQ-QIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNS-------TFEMPPDVECF 1565
            K+G++ K   +G++S     S+S  P  +G++ + +   +  + I N PF + V +P   P+ ++ +G GL G   + P  F +D +G+ Q  +G ++EGPS  KI C +  +G+  + YS+ +PG Y + I  N+ ++   P  +   +S   + +     +  E     S ++   NS       TF   PD++ +
Sbjct:  886 KSGSMVKSNGDGSYS----CSYS--PYDAGTYILDVTYED--LPIKNSPFNIEV-VPGCDPSKVLVFGEGLEGGFTNQPNFFTIDLDGAGQGNLGLAIEGPSDAKINCTDNLDGTCTVEYSSTIPGTYDIYIKFNDVDVNGFPKHVFHRESTYEELLSLNAPMDDERTEADSILLSFNNSSGHDENLTFPKVPDIDSY 1074          

HSP 7 Score: 57.3806 bits (137), Expect = 1.759e-7
Identity = 31/85 (36.47%), Postives = 44/85 (51.76%), Query Frame = 3
Query: 4917 VHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAICIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRITV 5171
            +   G  L  G V     FV  T+G++ G+L   IEGPS+A+I   D + G   + Y  T PGEY   I  +  DIP+SP+   +
Sbjct:  553 IAAFGPGLTTGVVGKAAIFVTDTNGEL-GSLGFSIEGPSEAKIECCDNQDGSATICYWPTAPGEYAVHILCDGEDIPNSPYMANI 636          

HSP 8 Score: 56.6102 bits (135), Expect = 2.911e-7
Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 3
Query: 1185 IVSYGPGLYGSVADCPGVF-ILDTNGSDQQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPY 1424
            + +YGPGL       P  F I+  +     +  ++EGPSK +I C +  NGS  +TY  L+PG Y + I   + NI  SP+
Sbjct: 2652 VAAYGPGLSHGRTGLPAEFTIVTKDAGAGGLSLAIEGPSKAEIVCKDNENGSCDVTYYPLIPGDYSIIIKFADHNIPGSPF 2732          

HSP 9 Score: 55.8398 bits (133), Expect = 5.196e-7
Identity = 38/142 (26.76%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 1056 LSFSLIPILSGSFDIFIKKNEYSMEILNKPFRVCV--NLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD-QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICDSPYSIVIVKSNKVDEIKKV 1472
            L  S  P   G+   FI   +    IL  PF++ V  N       +  +G GL   +++    F +DT  +    +  S+EGPSK +IEC +  +G+  ++Y+   PG Y ++I    E++  SP+++ I        ++K+
Sbjct: 2790 LGISFTPREVGNH--FINVYQSGAHILGSPFKIVVGQNEIGDASKVRVFGEGLKCGISNEMNSFTVDTREAGYGGLSLSIEGPSKAEIECRDNYDGTCQVSYTPSEPGTYMINIKYANEHVSGSPFAVKITGEPSAKLMEKI 2929          
The following BLAST results are available for this feature:
BLAST of Filamin A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FLNB1.490e-3927.09filamin B [Source:HGNC Symbol;Acc:HGNC:3755][more]
FLNB1.708e-3927.09filamin B [Source:HGNC Symbol;Acc:HGNC:3755][more]
FLNB1.775e-3927.09filamin B [Source:HGNC Symbol;Acc:HGNC:3755][more]
FLNB1.836e-3927.09filamin B [Source:HGNC Symbol;Acc:HGNC:3755][more]
FLNA1.029e-3726.46filamin A [Source:HGNC Symbol;Acc:HGNC:3754][more]
back to top
BLAST of Filamin A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fln-13.653e-2931.72FiLamiN (Actin binding protein) homolog [Source:U... [more]
fln-14.564e-2932.00FiLamiN (Actin binding protein) homolog [Source:U... [more]
fln-14.842e-2932.00FiLamiN (Actin binding protein) homolog [Source:U... [more]
fln-15.313e-2932.00FiLamiN (Actin binding protein) homolog [Source:U... [more]
fln-15.497e-2932.00FiLamiN (Actin binding protein) homolog [Source:U... [more]
back to top
BLAST of Filamin A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cher5.877e-3724.61gene:FBgn0014141 transcript:FBtr0089471[more]
cher7.308e-3724.44gene:FBgn0014141 transcript:FBtr0337101[more]
cher8.641e-3724.44gene:FBgn0014141 transcript:FBtr0303364[more]
cher1.156e-3624.61gene:FBgn0014141 transcript:FBtr0290014[more]
cher1.156e-3624.61gene:FBgn0014141 transcript:FBtr0337100[more]
back to top
BLAST of Filamin A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
flnb6.474e-4927.19filamin B, beta (actin binding protein 278) [Sourc... [more]
CR352234.31.398e-3928.07filamin A, alpha (actin binding protein 280) [Sour... [more]
CR352234.21.398e-3928.07filamin A, alpha (actin binding protein 280) [Sour... [more]
flna3.038e-3928.22filamin A, alpha (actin binding protein 280) [Sour... [more]
flncb4.176e-3926.91filamin C, gamma b (actin binding protein 280) [So... [more]
back to top
BLAST of Filamin A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FLNB1.415e-3926.95filamin B [Source:NCBI gene;Acc:100485165][more]
FLNB1.780e-3927.02filamin B [Source:NCBI gene;Acc:100485165][more]
FLNB2.192e-3927.02filamin B [Source:NCBI gene;Acc:100485165][more]
FLNB2.250e-3927.02filamin B [Source:NCBI gene;Acc:100485165][more]
FLNB2.301e-3927.02filamin B [Source:NCBI gene;Acc:100485165][more]
back to top
BLAST of Filamin A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Flnb1.684e-3926.89filamin, beta [Source:MGI Symbol;Acc:MGI:2446089][more]
Flna3.803e-3837.70filamin, alpha [Source:MGI Symbol;Acc:MGI:95556][more]
Flna4.086e-3826.83filamin, alpha [Source:MGI Symbol;Acc:MGI:95556][more]
Flna4.086e-3826.83filamin, alpha [Source:MGI Symbol;Acc:MGI:95556][more]
Flna4.450e-3826.83filamin, alpha [Source:MGI Symbol;Acc:MGI:95556][more]
back to top
BLAST of Filamin A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O75369|FLNB_HUMAN8.203e-3927.09Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=... [more]
sp|Q80X90|FLNB_MOUSE1.178e-3826.89Filamin-B OS=Mus musculus OX=10090 GN=Flnb PE=1 SV... [more]
sp|Q8BTM8|FLNA_MOUSE3.113e-3726.83Filamin-A OS=Mus musculus OX=10090 GN=Flna PE=1 SV... [more]
sp|P21333|FLNA_HUMAN5.203e-3726.46Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=... [more]
sp|D3ZHA0|FLNC_RAT1.262e-3626.31Filamin-C OS=Rattus norvegicus OX=10116 GN=Flnc PE... [more]
back to top
BLAST of Filamin A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K3FEG06.185e-4724.64Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3FF657.350e-4724.64Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0X3P3Q81.783e-4626.33Filamin-A OS=Schistocephalus solidus OX=70667 GN=F... [more]
A0A0X3NX602.826e-4429.46Filamin-A (Fragment) OS=Schistocephalus solidus OX... [more]
A0A0X3PDR04.407e-4429.88Uncharacterized protein OS=Schistocephalus solidus... [more]
back to top
BLAST of Filamin A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
flnb3.101e-4528.33filamin B, beta (actin binding protein 278) [Sourc... [more]
FLNB9.621e-4224.37filamin B [Source:NCBI gene;Acc:103028460][more]
flna1.422e-4027.57filamin A, alpha (actin binding protein 280) [Sour... [more]
flncb6.027e-3927.87filamin C, gamma b (actin binding protein 280) [So... [more]
flnca4.765e-3626.63filamin-C [Source:NCBI gene;Acc:103033794][more]
back to top
BLAST of Filamin A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004210.19.904e-2136.03pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1... [more]
ENSPMAT00000004223.11.091e-2036.03pep scaffold:Pmarinus_7.0:GL476636:147693:235187:1... [more]
ENSPMAT00000004195.11.264e-2036.03pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1... [more]
ENSPMAT00000008111.11.853e-2029.71pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 ge... [more]
ENSPMAT00000006506.12.489e-1830.60pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-... [more]
back to top
BLAST of Filamin A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Filamin A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO469471.520e-2933.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO452542.295e-2532.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
ALPHA-ACTININ3.285e-1927.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424319.506e-1931.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303093.427e-1828.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Filamin A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
flnc8.982e-3927.66filamin C [Source:NCBI gene;Acc:101165476][more]
flnc1.006e-3827.93filamin C [Source:NCBI gene;Acc:101165476][more]
flnc1.065e-3827.93filamin C [Source:NCBI gene;Acc:101165476][more]
flnc1.203e-3827.72filamin C [Source:NCBI gene;Acc:101165476][more]
flnc1.459e-3827.89filamin C [Source:NCBI gene;Acc:101165476][more]
back to top
BLAST of Filamin A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000080268.10.000e+097.64SMESG000080268.1[more]
SMESG000080268.10.000e+097.34SMESG000080268.1[more]
SMESG000080268.10.000e+097.39SMESG000080268.1[more]
SMESG000080268.10.000e+096.36SMESG000080268.1[more]
SMESG000064795.11.003e-4725.70SMESG000064795.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032338 ID=SMED30032338|Name=Filamin A|organism=Schmidtea mediterranea sexual|type=transcript|length=6014bp
AAATGAAATTCAAATAAGTTCTTATTATTGCCCAATTAGCTTATCCAAGA
AACAAATCTCAAGAAATGAAGCGAACAAAATCTGAAATATTAAAAAGTCA
TAAAATTGAAAAAAAAGTTTTCACCCGATGGATAAATCATAAACTGAAGT
ATCACAACAAGTTCATTAGAGATCTTCAATTTGATTTGTGCAATGGCGAG
ATTTTAGTAGAATTGATAGAAATATTATCTCAAAAGAAACTGGAAAAAAT
TAGGTTTTCCAATCAAGATAGACAAAGTAGAATTTGTACTTTGAATAGCG
TTCTCATATTTCTTCGACTTGAAGGAATGGAACTGAAAAATATCGAGCCC
GTCGATATTCTCGATGGATCTGTAAAGAAAATTAAAGAACTTTTATGGAT
TCTGATTTTTCATTATTCAATCAAAACGTTTTTGGGAGAAAATAATTTTG
ACGAAATTGGAAAAAGTTTTTTAAATTGGTTGAATTCGAAGTTAGATGGA
TATTTCATTGATAATCTTAGTTCGGCTTGGAATAGTGGCATTGCAATCGG
TTTAATAGTGAACACTTGTGATCGAGATTTATGCACCGATGTTTTGAAAT
GGAACTCGAGTAATGCTTTAAATAATGCCCAGTTTGCTATGGAAGCCGCA
TTTCAATGCTTCATGATCCCACAACTGTTAAAACCTATTGAAATAATAGA
TACCAGTGCCACGGACAAGGCAATAATGACTTATGTTAGCCAGTTTTCTG
GTTTACTCCAGGAGAGAAATAATAATAAATACGATCTAACTGGTAAATGT
CTGTCAAGCGTAATTGATGATGGTGGAAACACGTCAATGATGTTGGCGGC
AATTTCAACTGATAATATCTCAGATTATCATATCCGTCAACTTGATAAAC
CGCCGGATGTCATCAAAGATGGACGTGTTGATCTTTTAATTAAAATTCCG
ACCATTGAAAAAGACATCGCTAAAAATCTTGTCGTGGAAGCCGTTGATAA
AAATGGAAACGTTTACAAATGTACTCGGAACGGAAATTTTTCAAAGTCAA
ATGAACTTTCATTTTCTTTAATTCCGATTCTGTCAGGAAGCTTTGATATT
TTCATTAAAAAAAATGAATATTCAATGGAAATTTTGAATAAGCCTTTTCG
AGTGTGCGTAAACTTGCCAAATAAAAAACCAACAATTGTTTCTTATGGCC
CTGGTCTTTATGGATCAGTTGCTGATTGTCCTGGTGTATTTATTCTAGAT
ACCAATGGTTCAGATCAGCAAATTGGTTTTTCAATGGAAGGTCCATCTAA
AACTAAAATTGAGTGTGCAAACATCGGAAATGGATCCGTTTTGATAACGT
ATAGTGCGTTATTGCCAGGCATATACCAGTTGTCAATAATGGTTAATGAA
GAAAATATCTGTGATTCTCCATATTCAATTGTGATTGTCAAATCTAATAA
AGTTGATGAAATTAAAAAAGTGAAAGTAATCGGATTGGAAAATAAAAATA
CGAAGTCATTTATTATTGATTCGAGGAATTCCACATTTGAAATGCCTCCA
GATGTTGAATGCTTTGATAAACTCGGAGTGAGTTCGAACAACATCCTTGT
GACAGAGCTTGAAAAGAAATACTTTCGCATTGAATGTCCATTGAATAATG
CCGAGCGATTAATCGTTTTCGTTGGGTACTTCATGGTTCAGGTAGAAGGC
TTCCCATACGCTATAGATTATTATGATTCCAACGAAGGCCAGAGAAAAGT
AGACCAATTTTCTACATTTTCCAGCTTGCAGGAGAAATGTCTTGAAATTC
TAAATCAAGACTTGGTCGATGCAATCGAATTATCGGTTCAAGATTTATGT
GTAGATACTATAAATGATGTCCTAGTAAATACAAGAACAAAGAAACTTAT
TATCAAACATGAAACATTTGAAGAGTCGCAGCTTAAAACGTTTAAATGGA
TCGACAAAAAATTTGGCCTTATTTTGTATGGAACAAGTTTAAGTGGTAGA
CCAATTAAAAAGGGAGAATGCCAAGTAGTTCAAATAGATCTCGATAGGTC
AATACAAGGCGGATCAATCGGATTTGTCTTAGAAGGTCCAATAGAAACTC
AAGTTCAATGTTTTGCTAAAGATGACGGGCAATATATTATTAAATTTCAA
CCAATGACAGCTGGCAAATATGAATTATTCGTTACAATTGACGGGAAATC
CATAGATGGAAGTCCATTTAGTATTACAGTTTCTGAAACTTCCGACACAG
GAGTCTTTACCCAAAGAAGTCCAATTTATAACTCCGATAAACATGAAATT
GTCACTCAACATCTTTCCGCCAATTCAATAAAAATTGGAAATACCCCAAC
AAATTGCGATGTTTCTTCATTGTCCAGCACTATCTTTAGTGGAAACGAAC
GGGTATTCAAATCTTTGTCTACAGAATATAAATCAAAGCCAGTACTTCTT
GATATGAAATCTCTTTCAATACCAAATAAAATAGTTAGCAATGAATGCGA
ATCATTGTTTTCTTCATCAAATACATCTGGTAATTCTATTCGATCAGGGG
TTTATAAAGCAAAAATTCGAAAACTTTCGCTGTTTTCAAACAAAGATCCA
ATCACGCGTGGTAATTTCTGTGGTTATAGAAGTAAGTCTGAAAATGACAA
CGAGTCATCAATCAGTTCCAGTACATCAATGGAAATTGAAAAACTTTCAC
AGAATTATCAAGAATCAGTGCTAATATTTTATGAGAATATGTTGTCTGCC
TTTACCAATTTGTCAGTAGTAGATATCATTTATTATGCCATTGAAAGAAT
TACAAATTTAATTCTACCAGACCCAATCCAAATTTCATCTTTCAATGATG
TAGTTTTTAAAAACACTTTTCGAAATTCATTAAATAGTGAATTTTCGTCT
GACAATAAACTTTCCACAAATTCCAGGGAAATACATTTAACCTTCAATGA
AATAACCAGCATAAAATACGACGAATCTCAAACATTATCCCAAATAACAA
CTCCAGCTGAATTGAAAATACAGGATTCGGGTAAATATAATACAATTAGT
GCGAGTGTGGATTCGCTGTTAAACTGCTACAGTGAAAAGTCCATTGGTAA
GCGACCAATTCCTGTGTTAAGAAGCAATCAGATTTCTTCATTTGAAGCTT
TACAAGACAATATTAACATGATTGATGAGACCTATGAGTATTCGGAAAAT
AATTTTCATGTGTTAAAATCAAAATGTGTTGAATCAAATTATCAAGACTC
GTCTTTCGGTAAATCAACCAATCCAATGACTCTGACATCGCACACTGAGA
TAGCAATGGGCGATTATCAAAAGTCCATTGGTGTTGATGTCGCATCTTCG
ATGTCATCGAATGCGATAAATACCAAAGGAGATTTGGCTAAATTCACTGA
TGCAGAAGTTGTTTTTGATTCGTCTAGTATTGAATCCAGAAAAACCTCAA
GTTTTATATCTGTGTATGACAAAGCCCTGACGAAAAACGTTTTTCCGATC
ACTGAAAAATCAAATTATAAAGACTGTCCTTCTAAATCAGTGGAAATGTC
AAAGGTTTCTGTGTATAACTTCAAAAACTTTAAATTAACAGCAGACAATT
CACTATTGTCTCAATTAAACAAAACCAAATTTCAAAACTTGACTGTTCCT
AAGGCAAGTAATAAGCATTCTTTGAATATGTCACCTAAACAGTCCAAGTT
AACATTAAATTATGAAAATACGGAAACCGAGAGCCTGGTATCATGTGAGT
CGATAGAGATTCCTTTGCACATTGAAGGAAGGGTTAAAAAGTTTAAGACC
AATTGTCTGGTTGTACATAAACAATTAACTGAAACAAGAAAAACAGAATC
ATTGATAAACTATCTAAACGTCTTTCAAACAAACACAAAATATTTCGTTG
AAAAACCGAAAATATTTTATGAACAAGTCAACGAAAACACTATGTCAACG
GTGTCGGTGTCGGAAAAGCTTCCTTTACTGTCGATGAACTACATTAGAAT
GATTCATTTTGAAGAGGAAGCTACTCCTTTTTTTGTTGATGAAAACCTCA
AAAAACACTTGGTAAGTGTTTCTTGTTTGGAATATTCAAAAACTCGAAAT
CTTGCAAATATTTCAATGCTCTTACCGAATTGCCATCAATTCCGTTGTCC
GAATCCTTATTTATCATACAGACACTCGGATAACAATGATAAACAATCGG
AAAATCCAAAGCTAGAAAATGTGATTTTTCAAGAAATGATACAGTTTTAC
GTGTCGAAATATGTAAAAGACTATTTGAAAAAGAAATTGAATTTGCGGAA
GCGAGAAATAAAAAAATCCACGGAAAAAAGCGCTCAAACATCATCGGTAA
TTTTGGAGGGAGATTCAATAAGAAACTTTTCAGATATCAATGTCCTCAAT
TTCAAAAGGCCGATAAATAAACGAGTCTCTGAAATCAGTATTCACAGAAG
TGAATCAAAAGAAATTCATTCTCAAGATCTGATGTTGTCTTCAAATGAGA
GTCAAGACATTTCTTCAGCAGTCGAGACGCTTGTTGATGCCATTACAGAT
ATTGCCAAAAATCATTTAATACTTTATCCGAGTCGTAGCAATGTTAAACG
CGTTGAAGAACTACTGAAACTATTGCCTCGATTACTTGAGCTGGGAAAAG
AGAAACGGCTTTATCATATAAACTTTTTAACCGATCAGTTAGAAGCGATA
CTAATAAATAGTACTGATCAAAGCAGCAACAAAGCTCTCAGTCAAATAAT
AAAGTCCATCAAGAGTTGTGTATATCTGGGAAAGTCAAACTCTAAAAGAA
AACGCCAAATTAATTCTGGCCACAGTAAACCGACAGATATGAAACAAAAC
ATATTGAGATTGGACAGTATCTCTGTGAAAACTGAGTCAGGAGATCTCAG
TCAAATTCCTTATGAAGTCCATGTTATCGGAAAGGCGCTATGCAAAGGCT
TTGTGAATTTCAATAATAAGTTTGTCGTGCATACCTCAGGGAAAATTCCG
GGAAACTTGGCTATTTGTATCGAAGGACCAAGTAAAGCAGAAATTAGTTT
CATGGACAAAAAAATAGGAATTTACATTGTCAGTTACAGAGTGACGATTC
CTGGTGAATATGTATGCGCAATAAGTTTTAATAAAGTTGATATTCCTCAT
TCGCCATTCAGAATTACAGTAGCAGATGATGTCAATCGCCGGATTCTCCA
TAAACATGTTAAACCGGATATATGTAGTGAGGTGGAAATGCAAAATAAAG
GAAATTCTACTTCGATAAAACCAGTGGGGAAAAATCTCATATTTCATGTT
TCAAGTCCGGAAATATTAAATTTGAACTGCTTTGTTACCGAACCTCATGG
AGGTTCCAGTTTTCATCCAATAAAAAAAATGTCCAAAACATCCAATAAAG
ATGGTTTTATAAATGTATTTGCCTCAACCATCGGAGTTTATAATATAGAT
TTTTACAATTTTTTGGGCGACAAAATAGGCCCTTCTTGGAAAGTAAAGAT
TGAAAATATTCACGGTTCTTTGAGGTCTACCACGCTGTCGTGCGATGTTG
ACATTCAGATCATTAATCCACTGATTGTGAATGAGATTTATCAAAACATT
TGCGCGTACGGAGATGGGCTGCAGCAAGCAACAGTTAATCGCAAAAATCA
TTTTTTCATTTTCCTCTGGAATTACTCAGAAAGTATAATTTGCAAAGAAC
CTTCGTTAGATGTTACGATAGACGGGCCTAGCAAAGTTCAAATTTCATGC
ATTGAAGACATTAATGGATACATATTCTGTTATATTCCAATTGTCATTGG
ACTTTATTTTATTGGTATCACATACTCAAATAAATGCCACATTCCAGGTT
CTCCGTTTAAGATTACGGTTTTGCGAGACCCAAATAGTGACTTGAACCAT
CAAGAATTCGAGAACCAATAATTTCTAAAATTTTGCAACATTTGTTGCAA
TTATTTACAAATTCAGAAAAGACTGTCAAAAAATTCTTTTTCTGATATAA
ATAAATAGTTACAG
back to top

protein sequence of SMED30032338-orf-1

>SMED30032338-orf-1 ID=SMED30032338-orf-1|Name=SMED30032338-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1952bp
MKRTKSEILKSHKIEKKVFTRWINHKLKYHNKFIRDLQFDLCNGEILVEL
IEILSQKKLEKIRFSNQDRQSRICTLNSVLIFLRLEGMELKNIEPVDILD
GSVKKIKELLWILIFHYSIKTFLGENNFDEIGKSFLNWLNSKLDGYFIDN
LSSAWNSGIAIGLIVNTCDRDLCTDVLKWNSSNALNNAQFAMEAAFQCFM
IPQLLKPIEIIDTSATDKAIMTYVSQFSGLLQERNNNKYDLTGKCLSSVI
DDGGNTSMMLAAISTDNISDYHIRQLDKPPDVIKDGRVDLLIKIPTIEKD
IAKNLVVEAVDKNGNVYKCTRNGNFSKSNELSFSLIPILSGSFDIFIKKN
EYSMEILNKPFRVCVNLPNKKPTIVSYGPGLYGSVADCPGVFILDTNGSD
QQIGFSMEGPSKTKIECANIGNGSVLITYSALLPGIYQLSIMVNEENICD
SPYSIVIVKSNKVDEIKKVKVIGLENKNTKSFIIDSRNSTFEMPPDVECF
DKLGVSSNNILVTELEKKYFRIECPLNNAERLIVFVGYFMVQVEGFPYAI
DYYDSNEGQRKVDQFSTFSSLQEKCLEILNQDLVDAIELSVQDLCVDTIN
DVLVNTRTKKLIIKHETFEESQLKTFKWIDKKFGLILYGTSLSGRPIKKG
ECQVVQIDLDRSIQGGSIGFVLEGPIETQVQCFAKDDGQYIIKFQPMTAG
KYELFVTIDGKSIDGSPFSITVSETSDTGVFTQRSPIYNSDKHEIVTQHL
SANSIKIGNTPTNCDVSSLSSTIFSGNERVFKSLSTEYKSKPVLLDMKSL
SIPNKIVSNECESLFSSSNTSGNSIRSGVYKAKIRKLSLFSNKDPITRGN
FCGYRSKSENDNESSISSSTSMEIEKLSQNYQESVLIFYENMLSAFTNLS
VVDIIYYAIERITNLILPDPIQISSFNDVVFKNTFRNSLNSEFSSDNKLS
TNSREIHLTFNEITSIKYDESQTLSQITTPAELKIQDSGKYNTISASVDS
LLNCYSEKSIGKRPIPVLRSNQISSFEALQDNINMIDETYEYSENNFHVL
KSKCVESNYQDSSFGKSTNPMTLTSHTEIAMGDYQKSIGVDVASSMSSNA
INTKGDLAKFTDAEVVFDSSSIESRKTSSFISVYDKALTKNVFPITEKSN
YKDCPSKSVEMSKVSVYNFKNFKLTADNSLLSQLNKTKFQNLTVPKASNK
HSLNMSPKQSKLTLNYENTETESLVSCESIEIPLHIEGRVKKFKTNCLVV
HKQLTETRKTESLINYLNVFQTNTKYFVEKPKIFYEQVNENTMSTVSVSE
KLPLLSMNYIRMIHFEEEATPFFVDENLKKHLVSVSCLEYSKTRNLANIS
MLLPNCHQFRCPNPYLSYRHSDNNDKQSENPKLENVIFQEMIQFYVSKYV
KDYLKKKLNLRKREIKKSTEKSAQTSSVILEGDSIRNFSDINVLNFKRPI
NKRVSEISIHRSESKEIHSQDLMLSSNESQDISSAVETLVDAITDIAKNH
LILYPSRSNVKRVEELLKLLPRLLELGKEKRLYHINFLTDQLEAILINST
DQSSNKALSQIIKSIKSCVYLGKSNSKRKRQINSGHSKPTDMKQNILRLD
SISVKTESGDLSQIPYEVHVIGKALCKGFVNFNNKFVVHTSGKIPGNLAI
CIEGPSKAEISFMDKKIGIYIVSYRVTIPGEYVCAISFNKVDIPHSPFRI
TVADDVNRRILHKHVKPDICSEVEMQNKGNSTSIKPVGKNLIFHVSSPEI
LNLNCFVTEPHGGSSFHPIKKMSKTSNKDGFINVFASTIGVYNIDFYNFL
GDKIGPSWKVKIENIHGSLRSTTLSCDVDIQIINPLIVNEIYQNICAYGD
GLQQATVNRKNHFFIFLWNYSESIICKEPSLDVTIDGPSKVQISCIEDIN
GYIFCYIPIVIGLYFIGITYSNKCHIPGSPFKITVLRDPNSDLNHQEFEN
Q*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036872CH_dom_sf
IPR001298Filamin/ABP280_rpt
IPR001715CH-domain
IPR013783Ig-like_fold
IPR017868Filamin/ABP280_repeat-like
IPR001589Actinin_actin-bd_CS
IPR014756Ig_E-set
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003779actin binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001715Calponin homology domainSMARTSM00033ch_5coord: 131..227
e-value: 2.3E-7
score: 40.5
coord: 15..116
e-value: 4.0E-11
score: 53.0
IPR001715Calponin homology domainPFAMPF00307CHcoord: 15..117
e-value: 1.2E-11
score: 44.8
coord: 133..229
e-value: 4.7E-9
score: 36.4
IPR001715Calponin homology domainPROSITEPS50021CHcoord: 13..118
score: 17.048
IPR001715Calponin homology domainPROSITEPS50021CHcoord: 129..232
score: 15.403
IPR001298Filamin/ABP280 repeatSMARTSM00557flmn_3coord: 636..725
e-value: 1.1E-4
score: 29.0
coord: 1614..1705
e-value: 1.4E-16
score: 71.1
coord: 1843..1938
e-value: 1.5E-5
score: 34.4
coord: 371..460
e-value: 8.6E-8
score: 41.9
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 1842..1937
e-value: 1.5E-16
score: 62.5
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 637..731
e-value: 7.5E-12
score: 47.2
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 1605..1711
e-value: 2.0E-20
score: 74.8
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 371..455
e-value: 1.3E-15
score: 59.7
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 327..370
e-value: 1.3E-15
score: 59.7
IPR036872CH domain superfamilyGENE3DG3DSA:1.10.418.10coord: 1..122
e-value: 2.3E-24
score: 87.5
IPR036872CH domain superfamilyGENE3DG3DSA:1.10.418.10coord: 125..229
e-value: 1.7E-20
score: 74.9
IPR036872CH domain superfamilySUPERFAMILYSSF47576Calponin-homology domain, CH-domaincoord: 11..227
IPR017868Filamin/ABP280 repeat-likePFAMPF00630Filamincoord: 1618..1699
e-value: 2.7E-7
score: 31.4
coord: 643..718
e-value: 1.9E-7
score: 31.9
IPR017868Filamin/ABP280 repeat-likePROSITEPS50194FILAMIN_REPEATcoord: 637..722
score: 17.15
IPR017868Filamin/ABP280 repeat-likePROSITEPS50194FILAMIN_REPEATcoord: 1615..1702
score: 18.774
IPR017868Filamin/ABP280 repeat-likePROSITEPS50194FILAMIN_REPEATcoord: 1843..1935
score: 18.26
IPR017868Filamin/ABP280 repeat-likePROSITEPS50194FILAMIN_REPEATcoord: 366..457
score: 16.842
NoneNo IPR availablePANTHERPTHR38537FAMILY NOT NAMEDcoord: 289..488
coord: 660..747
coord: 12..250
coord: 1612..1936
coord: 356..565
NoneNo IPR availableTMHMMTMhelixcoord: 1899..1918
IPR001589Actinin-type actin-binding domain, conserved sitePROSITEPS00019ACTININ_1coord: 15..24
IPR014756Immunoglobulin E-setSUPERFAMILYSSF81296E set domainscoord: 637..727
IPR014756Immunoglobulin E-setSUPERFAMILYSSF81296E set domainscoord: 1845..1937
IPR014756Immunoglobulin E-setSUPERFAMILYSSF81296E set domainscoord: 354..461
IPR014756Immunoglobulin E-setSUPERFAMILYSSF81296E set domainscoord: 1609..1707