Fe2OG dioxygenase domain-containing protein

Overview
NameFe2OG dioxygenase domain-containing protein
Smed IDSMED30032268
Length (bp)715
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fe2OG dioxygenase domain-containing protein (SMED30032268) t-SNE clustered cells

Violin plots show distribution of expression levels for Fe2OG dioxygenase domain-containing protein (SMED30032268) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fe2OG dioxygenase domain-containing protein (SMED30032268) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fe2OG dioxygenase domain-containing protein (SMED30032268) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032268

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30032268SMESG000044555.1 SmedASXL_009243SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: ALKBH6 (alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243])

HSP 1 Score: 199.134 bits (505), Expect = 2.165e-63
Identity = 95/227 (41.85%), Postives = 135/227 (59.47%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQA-----FIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++++S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  +   P  + +          +EPRSL ++    Y+  +HGI  A  D +D               S      L R TRVS TIR VP+ ++
Sbjct:   10 ALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLF--GGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRRPEDDDPTEQPRPPPRPTTSLLLEPRSLLVLRGPAYTRLLHGIAAARVDALDAASSPPN---AAACPSARPGACLVRGTRVSLTIRRVPRVLR 231
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: ALKBH6 (alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243])

HSP 1 Score: 199.519 bits (506), Expect = 3.668e-63
Identity = 95/227 (41.85%), Postives = 135/227 (59.47%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQA-----FIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++++S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  +   P  + +          +EPRSL ++    Y+  +HGI  A  D +D               S      L R TRVS TIR VP+ ++
Sbjct:   38 ALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLF--GGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRRPEDDDPTEQPRPPPRPTTSLLLEPRSLLVLRGPAYTRLLHGIAAARVDALDAASSPPN---AAACPSARPGACLVRGTRVSLTIRRVPRVLR 259
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: ALKBH6 (alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243])

HSP 1 Score: 119.013 bits (297), Expect = 2.024e-33
Identity = 50/110 (45.45%), Postives = 74/110 (67.27%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG 334
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++++S+F    +  NH L+N+Y  GEGI+ H  G
Sbjct:   10 ALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLFG--GLPANHVLVNQYLPGEGIMHHQPG 117
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: ALKBH6 (alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243])

HSP 1 Score: 88.5817 bits (218), Expect = 5.769e-22
Identity = 37/85 (43.53%), Postives = 56/85 (65.88%), Query Frame = 2 
Query:   80 EKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG 334
            E + + + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++++S+F    +  NH L+N+Y  GEGI+ H  G
Sbjct:   12 EPFRVEQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLFG--GLPANHVLVNQYLPGEGIMHHQPG 94
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: ALKBH6 (alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243])

HSP 1 Score: 72.0182 bits (175), Expect = 1.777e-15
Identity = 29/54 (53.70%), Postives = 39/54 (72.22%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGG 166
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGG
Sbjct:   30 ALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGG 83
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: B0564.2 (pep chromosome:WBcel235:IV:13107659:13111500:1 gene:WBGene00007202.1 transcript:B0564.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:B0564.2)

HSP 1 Score: 186.422 bits (472), Expect = 6.271e-59
Identity = 92/225 (40.89%), Postives = 140/225 (62.22%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMI-LEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            ++ +F++K+ P +  YIPN+ID+E+E    +   N P+ KW  L++RRLQN+GG+  +  +I  +D P  +  +MTKIND+ IF +     NH L+NEY+ G+GI+PH DGP ++ IV T++L SH +L+ Y+P   +      ER +    +EPRSL++M +D Y+  +HGI E  +DLI+  K  N        + ELAN+ L R TR+S T+RNV K  KL 
Sbjct:   10 NIKKFIVKSAPATMIYIPNWIDEEEENLYKSCIENAPQPKWRVLANRRLQNYGGVVGKTALIPTDDFPVELKYLMTKINDLGIFKN---PVNHVLVNEYEAGQGIMPHTDGPAFHRIVTTVTLGSHCLLDMYDPVDQEIAKSEEERYVGSMLLEPRSLFIMTDDAYTRMLHGIAERETDLIEPGKVFNC-------TEELANKRLDRDTRISITVRNVEKVSKLG 224
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: B0564.2 (pep chromosome:WBcel235:IV:13111212:13111439:1 gene:WBGene00007202.1 transcript:B0564.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:B0564.2)

HSP 1 Score: 64.6994 bits (156), Expect = 1.006e-13
Identity = 33/73 (45.21%), Postives = 45/73 (61.64%), Query Frame = 2 
Query:  455 FIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKL 673
             +EPRSL++M +D Y+  +HGI E  +DLI+  K  N        + ELAN+ L R TR+S T+RNV K  KL
Sbjct:    2 LLEPRSLFIMTDDAYTRMLHGIAERETDLIEPGKVFNC-------TEELANKRLDRDTRISITVRNVEKVSKL 67
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG6144 (gene:FBgn0032259 transcript:FBtr0100565)

HSP 1 Score: 189.889 bits (481), Expect = 3.544e-60
Identity = 92/235 (39.15%), Postives = 142/235 (60.43%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFY-------EPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLSKSF 685
            M  + F ++ CP +  YIPNFI  E+E+ +L+     PK +WT L +RRL N+GG+P   GMI E+IPEW+   + K+N++ +F   N   NH L+NEY  G+GILPH DGPL++PI++T+S  +HTVL F        E ++ D+        + +  +EPRSL ++ + +Y+ ++H I E   D++  D+  N D  +  Y  ++ +  + RS R+S TIRNVPKT K+   F
Sbjct:    1 MDFTGFEVRKCPPTVMYIPNFITSEEEQRILSHIERTPKPRWTQLLNRRLVNYGGVPHPNGMIAEEIPEWLQTYVDKVNNLGVFESQN--ANHVLVNEYLPGQGILPHTDGPLFHPIISTISTGAHTVLEFVKREDTTTETEAGDQ---TTREVLFKLLLEPRSLLILKDTLYTDYLHAISETSEDVL-CDRISNYDLCENTY--KIGDHLVRRSPRISLTIRNVPKTSKMKLKF 227
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG6144 (gene:FBgn0032259 transcript:FBtr0304137)

HSP 1 Score: 189.889 bits (481), Expect = 3.544e-60
Identity = 92/235 (39.15%), Postives = 142/235 (60.43%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFY-------EPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLSKSF 685
            M  + F ++ CP +  YIPNFI  E+E+ +L+     PK +WT L +RRL N+GG+P   GMI E+IPEW+   + K+N++ +F   N   NH L+NEY  G+GILPH DGPL++PI++T+S  +HTVL F        E ++ D+        + +  +EPRSL ++ + +Y+ ++H I E   D++  D+  N D  +  Y  ++ +  + RS R+S TIRNVPKT K+   F
Sbjct:    1 MDFTGFEVRKCPPTVMYIPNFITSEEEQRILSHIERTPKPRWTQLLNRRLVNYGGVPHPNGMIAEEIPEWLQTYVDKVNNLGVFESQN--ANHVLVNEYLPGQGILPHTDGPLFHPIISTISTGAHTVLEFVKREDTTTETEAGDQ---TTREVLFKLLLEPRSLLILKDTLYTDYLHAISETSEDVL-CDRISNYDLCENTY--KIGDHLVRRSPRISLTIRNVPKTSKMKLKF 227
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:317736])

HSP 1 Score: 192.971 bits (489), Expect = 3.178e-61
Identity = 92/226 (40.71%), Postives = 140/226 (61.95%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSN-DKIIPINE--RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            + L ++++K  P + YYIP+FI + +E++LL + Y  PK KWT LS RRLQNWGGLP+ KGM+ E +P+W+ E   KI+ +  FA      NH L+NEY+ GEGI+PH DGPLY+P V T+++ SHT+L+FY P    +   P  E  R +    ++ +SL ++ +D+Y  ++HGI     D++      +   ++   +       L RSTRVS TIR+VPK ++
Sbjct:    9 VDLEKYIVKEAPPTVYYIPDFISEAEEEFLLQQVYRAPKPKWTQLSGRRLQNWGGLPNPKGMLAEKLPDWLLEYTEKISALGAFAGKT--ANHVLVNEYKPGEGIMPHEDGPLYHPTVTTITVGSHTLLDFYRPVCQAEPDAPQTEESRYMLSLLVQRKSLLILQDDMYKCYLHGIRGVCEDVL------SEHVVNISSTGAQVGDTLPRSTRVSLTIRHVPKIIR 226
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: BX005407.1 (pep chromosome:GRCz11:5:36641200:36674139:-1 gene:ENSDARG00000116148.1 transcript:ENSDART00000188100.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX005407.1)

HSP 1 Score: 57.3806 bits (137), Expect = 7.055e-10
Identity = 35/122 (28.69%), Postives = 55/122 (45.08%), Query Frame = 2 
Query:   38 KSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP 403
            K+ YY  N+       +L  + +  P  K T L+++ L  WG LP  K + +        E   +I   S+F+ +   T H LLN +   E I  H   P+Y+    T ++  HT+ N Y P
Sbjct:   20 KTKYYCLNYTSMVNHMHLAQQIWRAPAPKPTTLTYKHLAQWGLLPYPKTIEIAKNGHLHLEWTERITACSVFSCHT--TLHLLLNRHGPNESITLHKRAPVYHTSPKTCAVGEHTLFNSYRP 139
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:ZFIN;Acc:ZDB-GENE-100922-251])

HSP 1 Score: 53.1434 bits (126), Expect = 9.186e-8
Identity = 56/226 (24.78%), Postives = 96/226 (42.48%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKFYNVPKS----KWTYLSHRRLQNWG-------GLPDQKGMILEDIPEWVNEIMTKI---NDISIFADNNIQTNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRS-TRVSFTIRNVPKT 664
            P     + +F+  E+E  +L      P +        L HRR++++G          D+   +   +P   + ++ +      IS+  D         +N+YQ G+GI PH D    +   + +LSL + TV++F  P         + R +A    E RSL +M  +    + HGI     D++ V +      +    +S+L+N  LSR  TR S T R +  T
Sbjct:  131 PPGLSVLEDFVSLEEELQILKAVDWTPHADDVTAQKALKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPVECDALLQRCLAGGHISVLPDQ------LTVNQYQSGQGIPPHVDTHSPFEDTILSLSLGAKTVMDFKHP---------DGRSVAVVLPE-RSLLVMKGESRYLWTHGITPRKFDVVPVSETGGSGVM----TSDLSNLTLSRRDTRTSLTFRKIRHT 336
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:779668])

HSP 1 Score: 202.986 bits (515), Expect = 6.317e-65
Identity = 100/233 (42.92%), Postives = 144/233 (61.80%), Query Frame = 2 
Query:    8 LSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPIN-------ERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLSKSF 685
            L +FL++  P++ YY+P +I K +E+YLL + YN PK KWT LS R+LQNWGG+P  +GM+ E +P W+     +I+ + +F D+    NH L+NEY  GEGI+PH DGP+YYP V T+SL SHT+L+FY P + D     N       +R I    +EPRSL ++ E++Y+ ++HGI    SD +   K  N++       +  + + L R TRVS TIR VPK +K S  F
Sbjct:   10 LEKFLVEKVPRAAYYVPEYISKAEEEYLLRQVYNAPKPKWTQLSGRKLQNWGGIPHVRGMVQEKLPSWLQTYADQISSLGVFGDHC--ANHVLVNEYNAGEGIMPHEDGPMYYPTVTTISLGSHTLLDFYVPINKDCPEDQNQVSSTEEQRHILSLLLEPRSLLVVREELYTSYLHGICPKTSDTLG-PKAANLE-----KCTAHSGETLQRGTRVSLTIRFVPKVLKTSILF 234
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:779668])

HSP 1 Score: 128.642 bits (322), Expect = 9.787e-37
Identity = 69/174 (39.66%), Postives = 101/174 (58.05%), Query Frame = 2 
Query:  185 MILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSND------KIIPINE-RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLSKSF 685
            M+ E +P W+     +I+ + +F D+    NH L+NEY  GEGI+PH DGP+YYP V T+SL SHT+L+FY P + D      ++    E R I    +EPRSL ++ E++Y+ ++HGI    SD +   K  N++       +  + + L R TRVS TIR VPK +K S  F
Sbjct:    1 MVQEKLPSWLQTYADQISSLGVFGDHC--ANHVLVNEYNAGEGIMPHEDGPMYYPTVTTISLGSHTLLDFYVPINKDCPEDQNQVSSTEEQRHILSLLLEPRSLLVVREELYTSYLHGICPKTSDTLG-PKAANLE-----KCTAHSGETLQRGTRVSLTIRFVPKVLKTSILF 166
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:NCBI gene;Acc:550051])

HSP 1 Score: 64.6994 bits (156), Expect = 2.107e-11
Identity = 53/216 (24.54%), Postives = 96/216 (44.44%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKF-YNVPKSKWTYLSHRRLQNWG-------GLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
            P     + +F+  E+E+ +L    ++   S    L HRR++++G          D+   +   +P++  E + K   I +   +  Q     +N+Y+ G+GI PH D    +   + +LSL +  V++F  P  N  ++P+         +  RSL +M+ +    + HGI     D+I V +   +  +         N+   RSTR SFT R V
Sbjct:  145 PPGLIIVEDFVSPEQERTMLESIDWDSETSSQKSLKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPDFCTEALRKCVQIGLIKHDPDQLT---INQYEPGQGIPPHVDTHSAFEDEILSLSLGAEIVMDFKHP--NGSVVPV--------MLPQRSLLIMSGESRYLWTHGITPRKFDVIQVSEGQTVGTISGNSGELTLNK---RSTRTSFTFRKV 344
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:NCBI gene;Acc:550051])

HSP 1 Score: 64.3142 bits (155), Expect = 2.241e-11
Identity = 53/216 (24.54%), Postives = 96/216 (44.44%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKF-YNVPKSKWTYLSHRRLQNWG-------GLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
            P     + +F+  E+E+ +L    ++   S    L HRR++++G          D+   +   +P++  E + K   I +   +  Q     +N+Y+ G+GI PH D    +   + +LSL +  V++F  P  N  ++P+         +  RSL +M+ +    + HGI     D+I V +   +  +         N+   RSTR SFT R V
Sbjct:  142 PPGLIIVEDFVSPEQERTMLESIDWDSETSSQKSLKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPDFCTEALRKCVQIGLIKHDPDQLT---INQYEPGQGIPPHVDTHSAFEDEILSLSLGAEIVMDFKHP--NGSVVPV--------MLPQRSLLIMSGESRYLWTHGITPRKFDVIQVSEGQTVGTISGNSGELTLNK---RSTRTSFTFRKV 341
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:NCBI gene;Acc:550051])

HSP 1 Score: 64.3142 bits (155), Expect = 2.512e-11
Identity = 53/216 (24.54%), Postives = 96/216 (44.44%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKF-YNVPKSKWTYLSHRRLQNWG-------GLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
            P     + +F+  E+E+ +L    ++   S    L HRR++++G          D+   +   +P++  E + K   I +   +  Q     +N+Y+ G+GI PH D    +   + +LSL +  V++F  P  N  ++P+         +  RSL +M+ +    + HGI     D+I V +   +  +         N+   RSTR SFT R V
Sbjct:  146 PPGLIIVEDFVSPEQERTMLESIDWDSETSSQKSLKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPDFCTEALRKCVQIGLIKHDPDQLT---INQYEPGQGIPPHVDTHSAFEDEILSLSLGAEIVMDFKHP--NGSVVPV--------MLPQRSLLIMSGESRYLWTHGITPRKFDVIQVSEGQTVGTISGNSGELTLNK---RSTRTSFTFRKV 345
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: Alkbh6 (alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037])

HSP 1 Score: 215.698 bits (548), Expect = 4.285e-70
Identity = 101/229 (44.10%), Postives = 140/229 (61.14%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPIN-----ERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++D+S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  D  +P+      +R I    +EPRSL ++    Y+  +HGI     D +D           K   S L    L R TRVS TIR VP+ ++ S
Sbjct:   10 ALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFG--GLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPDDDVPMEQPRPPQRPITSLLVEPRSLLVLRGTAYTRLLHGISATRVDELDATSLPPNATACK---SALPGAHLVRGTRVSLTIRRVPRVLRAS 233
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: Alkbh6 (alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037])

HSP 1 Score: 193.741 bits (491), Expect = 8.608e-62
Identity = 92/207 (44.44%), Postives = 127/207 (61.35%), Query Frame = 2 
Query:   56 PNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPIN-----ERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPK 661
            P  +++E+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++D+S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  D  +P+      +R I    +EPRSL ++    Y+  +HGI     D +D           K   S L    L R TRVS TIR VP+
Sbjct:   13 PFRVEQEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFG--GLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPDDDVPMEQPRPPQRPITSLLVEPRSLLVLRGTAYTRLLHGISATRVDELDATSLPPNATACK---SALPGAHLVRGTRVSLTIRRVPR 214
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: Alkbh6 (alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037])

HSP 1 Score: 97.8265 bits (242), Expect = 1.115e-25
Identity = 41/88 (46.59%), Postives = 62/88 (70.45%), Query Frame = 2 
Query:   56 PNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGIL 319
            P  +++E+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++D+S+F    +  NH L+N+Y  GEGI+
Sbjct:   13 PFRVEQEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFG--GLPANHVLVNQYLPGEGIM 98
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8K2U2|ALKB6_MOUSE (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 OS=Mus musculus OX=10090 GN=Alkbh6 PE=2 SV=3)

HSP 1 Score: 215.698 bits (548), Expect = 2.998e-69
Identity = 101/229 (44.10%), Postives = 140/229 (61.14%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPIN-----ERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++D+S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  D  +P+      +R I    +EPRSL ++    Y+  +HGI     D +D           K   S L    L R TRVS TIR VP+ ++ S
Sbjct:   10 ALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFG--GLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPDDDVPMEQPRPPQRPITSLLVEPRSLLVLRGTAYTRLLHGISATRVDELDATSLPPNATACK---SALPGAHLVRGTRVSLTIRRVPRVLRAS 233
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5PQ59|ALKB6_XENLA (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 OS=Xenopus laevis OX=8355 GN=alkbh6 PE=2 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 1.848e-65
Identity = 103/234 (44.02%), Postives = 143/234 (61.11%), Query Frame = 2 
Query:    8 LSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP--------QSNDKIIPINE-RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLID--VDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            L  FL++  P + YY+P +I K +E+YLL + YN PK KWT LS R+LQNWGGLP  +GM+ E +P W+ +   +I+ + +F D++   NH L+NEY  GEGI+PH DGP+YYP V T+SL SHT+L+FY P        Q+ DK+    E R +    +EPRSL ++ E++Y+ ++HGI    SD +   V    N        S+  A   L R TRVS TIR VPK +K S
Sbjct:   10 LDSFLVEKIPLAAYYVPEYISKSEEEYLLRQVYNAPKPKWTQLSGRKLQNWGGLPHSRGMVQEKLPSWLQKYTDQISSLGVFGDHS--ANHVLVNEYNAGEGIMPHEDGPMYYPTVTTISLGSHTLLDFYVPINKECQETQNQDKVASTEEQRHMLSLLLEPRSLLVVREELYTSYLHGICPRTSDTLSPMVANLGN--------STAHAGDTLQRGTRVSLTIRFVPKVLKTS 233
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3KRA9|ALKB6_HUMAN (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 OS=Homo sapiens OX=9606 GN=ALKBH6 PE=1 SV=2)

HSP 1 Score: 199.134 bits (505), Expect = 1.040e-62
Identity = 95/227 (41.85%), Postives = 135/227 (59.47%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQA-----FIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++++S+F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  +   P  + +          +EPRSL ++    Y+  +HGI  A  D +D               S      L R TRVS TIR VP+ ++
Sbjct:   10 ALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLF--GGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRRPEDDDPTEQPRPPPRPTTSLLLEPRSLLVLRGPAYTRLLHGIAAARVDALDAASSPPN---AAACPSARPGACLVRGTRVSLTIRRVPRVLR 231
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6IQE9|ALKB6_DANRE (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 OS=Danio rerio OX=7955 GN=alkbh6 PE=2 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 2.399e-60
Identity = 92/226 (40.71%), Postives = 140/226 (61.95%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSN-DKIIPINE--RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            + L ++++K  P + YYIP+FI + +E++LL + Y  PK KWT LS RRLQNWGGLP+ KGM+ E +P+W+ E   KI+ +  FA      NH L+NEY+ GEGI+PH DGPLY+P V T+++ SHT+L+FY P    +   P  E  R +    ++ +SL ++ +D+Y  ++HGI     D++      +   ++   +       L RSTRVS TIR+VPK ++
Sbjct:    9 VDLEKYIVKEAPPTVYYIPDFISEAEEEFLLQQVYRAPKPKWTQLSGRRLQNWGGLPNPKGMLAEKLPDWLLEYTEKISALGAFAGKT--ANHVLVNEYKPGEGIMPHEDGPLYHPTVTTITVGSHTLLDFYRPVCQAEPDAPQTEESRYMLSLLVQRKSLLILQDDMYKCYLHGIRGVCEDVL------SEHVVNISSTGAQVGDTLPRSTRVSLTIRHVPKIIR 226
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5UR03|YL905_MIMIV (Uncharacterized protein L905 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_L905 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 4.996e-14
Identity = 61/211 (28.91%), Postives = 103/211 (48.82%), Query Frame = 2 
Query:   41 SFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGL-----PDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYP-IVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
             F  I +++  ++EK LL K   + +S+W     RRLQ +        P     I   IP++++++   IN + +    + + +  ++NEY+ GEG+ PH D   YY  ++  LSL S T++ FY+ +      PI E+K  + +I PRSLY++ +D    + HGI     D                   E+  +++ R TR+S T RNV
Sbjct:   15 GFSIIHDYVTPDQEKKLLKK---INESEWVVDYQRRLQYYNYRNELFEPYDLIPIPNKIPKYLDQL---INQMILDKIIDQKPDQIIVNEYKPGEGLKPHFDRKDYYQNVIIGLSLGSGTIMEFYKNK------PIPEKK--KIYIPPRSLYIIKDDARYIWKHGIPPRKYD-------------------EINGKKIPRETRISITFRNV 192
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A1S3DNW2 (alpha-ketoglutarate-dependent dioxygenase alkB homolog 6-like OS=Diaphorina citri OX=121845 GN=LOC103522191 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 1.355e-67
Identity = 101/225 (44.89%), Postives = 148/225 (65.78%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            +++ +++IK  P + YYIP+FI +E+E +LLNK Y+VPK KWT LS+R+LQNWGG+P  KGMI E +PEW++  + +IN + +F   +++ NH L+NEY  G+GI+PH DGPLYYP ++T+S  SHT+LNFYEP    +       ++   F++ RSL ++ +D+Y  ++HGI     D +  D             S   NQ L+RSTRVS TIR+VPKT K +
Sbjct:    6 VNVEKYVIKKAPPTVYYIPDFITREEESHLLNKIYSVPKPKWTQLSNRKLQNWGGIPHPKGMIAEKLPEWLDTYLERINQLGVF--ESVKPNHVLINEYLAGQGIMPHFDGPLYYPTISTISCGSHTILNFYEPDRTSE-----GSEVCSIFVDARSLLILQDDMYEKYVHGISSKTDDTLSSDIL--------NCCSSSPNQMLNRSTRVSLTIRHVPKTTKFT 215
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: C3XZ62 (Fe2OG dioxygenase domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_202284 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 1.823e-67
Identity = 105/229 (45.85%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP--------QSNDKII-PINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLSKSFKFR 694
            P++ YYIP+FI +E+E YLL K Y  PK KWT LS+RRLQNWGGLP  KGM++E +PEW+     +I+ + +F D     NH L+NEYQQG+GI+PH DGPL+YP + T++L SHT+L+FY+P         S +++  P +ER      +EPRSL ++ ED+Y +F+HGI E  +D I  D+  N+               L+R+TRVS TIR+VPKT+K+      R
Sbjct:   10 PQTAYYIPDFITEEEESYLLAKVYAAPKPKWTQLSNRRLQNWGGLPHPKGMVVEKLPEWLQMCADRIHSLGVFQDK--MPNHVLVNEYQQGQGIMPHEDGPLFYPTITTVNLGSHTMLDFYKPLPGGEGGAGSTEQVTAPCDERYTMSFLLEPRSLLVLQEDLYHHFLHGIAERSADSI-TDRVTNL----VSCGGAAVGDTLTRATRVSLTIRHVPKTLKVQLRLGRR 231
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A2B4REA9 (Alpha-ketoglutarate-dependent dioxygenase alkB-like 6 OS=Stylophora pistillata OX=50429 GN=alkbh6 PE=4 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 9.180e-67
Identity = 102/230 (44.35%), Postives = 148/230 (64.35%), Query Frame = 2 
Query:    8 LSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP--------QSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKL 673
            L  +LIK  P   +YIPNFI +++EK+LL++    PK KWT LS RRLQNWGGLP  KGM+ E +P W+ +  T++  +S+F  N +  NH L+NEY+ G+GI+PH DGPL+YP+V+T++L SHT L+FY P        + N   + ++ER      +EPRSL+++ ED+Y  ++HGI E   D++  DK  N+D       + +    L R+TR+S TIRNVPK +K 
Sbjct:   10 LESYLIKKAPPKAFYIPNFISEDEEKFLLDQINGAPKPKWTKLSGRRLQNWGGLPHPKGMVPEKLPRWLEKHTTQVGSLSVF--NTVTPNHVLVNEYEPGQGIMPHEDGPLFYPVVSTINLGSHTFLDFYHPLNKREENTEENSSSLTLDERYFMSLLLEPRSLFILTEDLYHNYLHGIAERTYDVV-TDKVANLD----ACKNTILGDTLQRTTRISLTIRNVPKILKF 232
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A1U7QM69 (alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform X1 OS=Mesocricetus auratus OX=10036 GN=Alkbh6 PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 1.531e-66
Identity = 99/229 (43.23%), Postives = 142/229 (62.01%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERK-----IAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKLS 676
            +L  F ++  P   YY+P+FI KE+E+YLL + +N PK KWT LS R+LQNWGGLP  +GM+ E +P W+   + K++D+ +F    +  NH L+N+Y  GEGI+PH DGPLYYP V+T+SL SHTVL+FYEP+  +  +PI + +     I    +EPRSL ++    Y++ +HGI   L D +D     ++        S L    L R TRVS TIR VP+ ++ S
Sbjct:   10 ALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLGLF--GGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPEDDVPIEQPRPPPQPITSLLVEPRSLLVLRGTAYTHLLHGIAATLVDELDA---TSLPPNAAACQSALPGAHLVRGTRVSLTIRRVPRVLRAS 233
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A3P9K6T9 (AlkB homolog 6 OS=Oryzias latipes OX=8090 PE=4 SV=1)

HSP 1 Score: 212.231 bits (539), Expect = 4.287e-65
Identity = 101/225 (44.89%), Postives = 145/225 (64.44%), Query Frame = 2 
Query:    8 LSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSN-DKIIPINE--RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKL 673
            L  F++K  P++ YYIP+FI +++E YLL + Y  PK+KWT LS RRLQNWGGLP  +GM+ E IP+W+     KI+ +  F       NH L+NEY+QGEGI+PH DGPLY+P V T+SL SHT+L+FY+P S  +   P  E  R +    + PRSL ++ +++Y + +HGI     DL+  ++  N+ F     +  L  + L+R TRVS TIR+VPK +K+
Sbjct:   37 LKRFVVKDAPQTVYYIPDFISEDEESYLLQQVYKAPKTKWTQLSGRRLQNWGGLPHPRGMVPEKIPDWLQAYCEKISSLDAFGGKT--ANHVLVNEYKQGEGIMPHEDGPLYHPTVTTISLGSHTLLDFYKPVSCMEGEAPQTEDNRYLLSLLVMPRSLLILQDEMYQHLLHGIQGQTHDLL-TEQVVNLSF-----TGALPGETLTRGTRVSLTIRHVPKVMKM 253
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:103044359])

HSP 1 Score: 189.889 bits (481), Expect = 4.028e-60
Identity = 93/224 (41.52%), Postives = 134/224 (59.82%), Query Frame = 2 
Query:    8 LSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP--QSNDKIIPINE-RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVK 670
            L EF++K  P + YY+P+FI + +E+YLL +    PK KWT LS RRLQNWGGLP  KGM+ E +P+W+     KI+ +  FA      NH L+NEY+  EGI+PH DGPLY+P V T+SL SHT+L+FY    Q+ D +    E R +    +  RSL ++  ++Y  ++HGI    +D +  ++  N+     +       + L R TRVS TIR+VPK  +
Sbjct:   11 LKEFIVKDAPPTVYYVPDFITEAEEEYLLQQVCRAPKPKWTQLSGRRLQNWGGLPHPKGMLAEKLPDWLLTYSQKISALGAFAGK--AANHVLVNEYKPEEGIMPHEDGPLYHPTVTTISLGSHTLLDFYTSVNQTQDGVPQTEESRYMLSLLVRRRSLLILQGEMYERYLHGIQGVAADTL-TERVVNLSVAGGQ-----VGETLPRGTRVSLTIRHVPKVCR 226
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:NCBI gene;Acc:103028213])

HSP 1 Score: 52.7582 bits (125), Expect = 9.985e-8
Identity = 48/172 (27.91%), Postives = 76/172 (44.19%), Query Frame = 2 
Query:  161 GGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQ--TNHALLNEYQQGEGILPHHDGPLYYP---IVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEP-RSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELS-RSTRVSFTIRNV 655
            GGLP Q G +L+                   ++ ++    +   +N+YQ+G+GI PH D   + P    + +LSL + TV++F  P              A A + P RSL +M  +    + HGI     D++   +    D      +S+L+N  LS R TR SFT R +
Sbjct:  200 GGLPPQCGAVLQ----------------RCLSEGHVDFLPDQLTVNQYQRGQGIPPHVD--THSPFEDTILSLSLGAKTVMDFRHPDGQ-----------AVAVVLPGRSLLVMKGESRYLWTHGITPRKFDVVPASE----DEGSGVVTSDLSNLTLSRRGTRTSFTFRKI 338
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Sea Lamprey
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:317736])

HSP 1 Score: 166.007 bits (419), Expect = 2.985e-51
Identity = 91/243 (37.45%), Postives = 133/243 (54.73%), Query Frame = 2 
Query:    5 SLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGG-LPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFY-------EPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQ-----ELSRSTRVSFTIRNVPKTVKLSKSFKFR 694
            S S  +    P + YY+P+F+   +E+ LL + Y  PK+KWT LS RRLQNWGG LPD +GM+   +P W+    ++++ + +F  +  Q NH L+NEY+ GEGI+PH DGPLYYP V TLSL SH+VL+FY       EP   D   P     +    ++ RSL ++    Y+  +HGI   ++D +        +     +++  A          R TRVS TIR+VP+TV+       R
Sbjct:    9 SCSLCVCLKVPPTIYYVPDFLSHGEEEMLLREVYKAPKTKWTQLSGRRLQNWGGGLPDPRGMLASPLPPWLAHPASRLSSLGLF--DGSQANHVLVNEYRPGEGIMPHEDGPLYYPTVTTLSLGSHSVLDFYPTVRSTQEPD-GDPECPAARSPVFSLLLDRRSLLVLRNSAYTELLHGIKPVMADDVATTAAGAANLALVPWANAGAGGEAAVWPAPRGTRVSLTIRHVPRTVRAPVVLTGR 248
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Sea Lamprey
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:ZFIN;Acc:ZDB-GENE-100922-251])

HSP 1 Score: 53.5286 bits (127), Expect = 1.265e-8
Identity = 58/228 (25.44%), Postives = 91/228 (39.91%), Query Frame = 2 
Query:   11 SEFLIKTCPKSFYYIPNFIDKEKEKYLLNKF---YNVPKSKWTYLSHRRLQNWG-------GLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQ--TNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
            SE   +  P     IP+ +  E E  LL+        P ++ + L HR +Q++G          D+   +   +P   +E++ K       +   IQ   N   +N+YQ G+GI PH D    +   + +LSL + TV+ F  P  +           A   +  RSL +M  +    + HGI     D++        D  +    S LA     R  R SFT R V
Sbjct:  130 SESCTEALPPGLKLIPDCVSSEYEDQLLSCLDWSRRQPTAQQS-LKHRCVQHFGYEFRYDNNNVDKDKPLDRGVPTMCDELVDKC-----LSAGYIQHRPNQLTVNQYQPGQGIPPHIDTHSAFEDGIMSLSLGASTVMEFRHPDGSH----------ASVLLPRRSLLVMAGESRYLWSHGITPRKFDVVPAPLPPPGDGAEGPQGSTLAQ----RGVRTSFTFRTV 337
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO36560 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIA5])

HSP 1 Score: 179.489 bits (454), Expect = 1.527e-56
Identity = 93/223 (41.70%), Postives = 143/223 (64.13%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEP---QSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPK 661
            + L++++++  P + YYIP F+ + ++  LL + Y+ PK KWT LS RRLQNWGGLP  KGM+ + +P W+ +  T +  + +F       NH L+NEY+ G+GI+PH DGPL++P+V+T+SL SHT+L+FY P    +  ++  + +R      +EPRSL L+ ED+Y+ ++HGI+    D+   D   N +    K S EL +  L RSTR+S TIR+VPK
Sbjct:    8 LDLTKYIVREAPPTVYYIPEFVTESEQADLLKQVYSAPKPKWTQLSGRRLQNWGGLPHPKGMVQDKLPPWLLKHATYLGKLPVFKGK--APNHVLVNEYEPGQGIMPHEDGPLFFPVVSTISLGSHTLLDFYHPLKKNTESQVTTLQDRYFMSLLLEPRSLLLLTEDLYTSYLHGIEGRAHDIFTTD-IVNRE--QCKLSKELGST-LIRSTRISLTIRHVPK 224
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: alkbh6 (alkB homolog 6 [Source:NCBI gene;Acc:317736])

HSP 1 Score: 206.453 bits (524), Expect = 1.377e-66
Identity = 98/217 (45.16%), Postives = 140/217 (64.52%), Query Frame = 2 
Query:   32 CPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSN-DKIIPINE--RKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTVKL 673
             P++ YYIP+FI +++E YLL + Y  PK+KWT LS RRLQNWGGLP  +GM+ E IP+W+     KI+ +  F       NH L+NEY+QGEGI+PH DGPLY+P V T+SL SHT+L+FY+P S  +   P  E  R +    + PRSL ++ +++Y + +HGI     DL+  ++  N+ F     +  L  + L+R TRVS TIR+VPK +K+
Sbjct:   18 APQTVYYIPDFISEDEESYLLQQVYKAPKTKWTQLSGRRLQNWGGLPHPRGMVPEKIPDWLQAFCEKISSLDAFGGKT--ANHVLVNEYKQGEGIMPHEDGPLYHPTVTTISLGSHTLLDFYKPVSCMEGEAPQTEDNRYLLSLLVMPRSLLILQDEMYQHLLHGIQGQTHDLL-TEQVVNLSF-----TGALPGETLTRGTRVSLTIRHVPKVMKM 226
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: alkbh8 (alkB homolog 8, tRNA methyltransferase [Source:NCBI gene;Acc:101169473])

HSP 1 Score: 55.8398 bits (133), Expect = 9.516e-9
Identity = 54/230 (23.48%), Postives = 89/230 (38.70%), Query Frame = 2 
Query:   35 PKSFYYIPNFIDKEKEKYLLNKFYNVPK----SKWTYLSHRRLQNWG------------------GLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDG-PLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV 655
            P+    + +F+  E+E  LLN     P     +    L HRR++++G                  GLPD+   IL+   E                  N+  +   +N+Y+ G+GI PH D    +   + +LSL + TV+ F  P          + ++A   +  RSL +M  +    + HGI     D++  +        +    S L      R TR SFT R +
Sbjct:  133 PEGLALVEHFVSPEEEAQLLNVIDWSPTQGDVTAQKSLKHRRVKHYGFEFRYDINNVDKDKPLAAGLPDECVPILQRCVEQ--------------GHTNVLPDQLTVNQYESGQGIPPHVDTHSAFEDTILSLSLGAKTVMEFRHP----------DGRVAAVVLPERSLLVMKGESRYLWSHGITPRKVDMVPAEAPRADAPTEPGIQSNLTLSR--RGTRTSFTFRKI 336
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Match: SMESG000044555.1 (SMESG000044555.1)

HSP 1 Score: 449.514 bits (1155), Expect = 6.151e-161
Identity = 217/222 (97.75%), Postives = 217/222 (97.75%), Query Frame = 2 
Query:    2 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQAFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVPKTV 667
            MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQ FIEPRSLYLM EDIYSYFMHGIDEALSDLI VDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNV KT 
Sbjct:    1 MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRLQNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQQGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQVFIEPRSLYLMTEDIYSYFMHGIDEALSDLIVVDKFCNMDFLDKKYSSELANQELSRSTRVSFTIRNVLKTT 222
The following BLAST results are available for this feature:
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ALKBH62.165e-6341.85alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243][more]
ALKBH63.668e-6341.85alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243][more]
ALKBH62.024e-3345.45alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243][more]
ALKBH65.769e-2243.53alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243][more]
ALKBH61.777e-1553.70alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243][more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
B0564.26.271e-5940.89pep chromosome:WBcel235:IV:13107659:13111500:1 gen... [more]
B0564.21.006e-1345.21pep chromosome:WBcel235:IV:13111212:13111439:1 gen... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG61443.544e-6039.15gene:FBgn0032259 transcript:FBtr0100565[more]
CG61443.544e-6039.15gene:FBgn0032259 transcript:FBtr0304137[more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
alkbh63.178e-6140.71alkB homolog 6 [Source:NCBI gene;Acc:317736][more]
BX005407.17.055e-1028.69pep chromosome:GRCz11:5:36641200:36674139:-1 gene:... [more]
alkbh89.186e-824.78alkB homolog 8, tRNA methyltransferase [Source:ZFI... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
alkbh66.317e-6542.92alkB homolog 6 [Source:NCBI gene;Acc:779668][more]
alkbh69.787e-3739.66alkB homolog 6 [Source:NCBI gene;Acc:779668][more]
alkbh82.107e-1124.54alkB homolog 8, tRNA methyltransferase [Source:NCB... [more]
alkbh82.241e-1124.54alkB homolog 8, tRNA methyltransferase [Source:NCB... [more]
alkbh82.512e-1124.54alkB homolog 8, tRNA methyltransferase [Source:NCB... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Alkbh64.285e-7044.10alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037][more]
Alkbh68.608e-6244.44alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037][more]
Alkbh61.115e-2546.59alkB homolog 6 [Source:MGI Symbol;Acc:MGI:2142037][more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8K2U2|ALKB6_MOUSE2.998e-6944.10Alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
sp|Q5PQ59|ALKB6_XENLA1.848e-6544.02Alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
sp|Q3KRA9|ALKB6_HUMAN1.040e-6241.85Alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
sp|Q6IQE9|ALKB6_DANRE2.399e-6040.71Alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
sp|Q5UR03|YL905_MIMIV4.996e-1428.91Uncharacterized protein L905 OS=Acanthamoeba polyp... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3DNW21.355e-6744.89alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
C3XZ621.823e-6745.85Fe2OG dioxygenase domain-containing protein OS=Bra... [more]
A0A2B4REA99.180e-6744.35Alpha-ketoglutarate-dependent dioxygenase alkB-lik... [more]
A0A1U7QM691.531e-6643.23alpha-ketoglutarate-dependent dioxygenase alkB hom... [more]
A0A3P9K6T94.287e-6544.89AlkB homolog 6 OS=Oryzias latipes OX=8090 PE=4 SV=... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
alkbh64.028e-6041.52alkB homolog 6 [Source:NCBI gene;Acc:103044359][more]
alkbh89.985e-827.91alkB homolog 8, tRNA methyltransferase [Source:NCB... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
alkbh62.985e-5137.45alkB homolog 6 [Source:NCBI gene;Acc:317736][more]
alkbh81.265e-825.44alkB homolog 8, tRNA methyltransferase [Source:ZFI... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO365601.527e-5641.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
alkbh61.377e-6645.16alkB homolog 6 [Source:NCBI gene;Acc:317736][more]
alkbh89.516e-923.48alkB homolog 8, tRNA methyltransferase [Source:NCB... [more]
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BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000044555.16.151e-16197.75SMESG000044555.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032268 ID=SMED30032268|Name=Fe2OG dioxygenase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=715bp
CATGTCATTATCAGAATTTCTTATAAAAACATGTCCAAAAAGTTTTTATT
ACATCCCAAATTTTATTGATAAAGAAAAAGAAAAATATTTGTTAAATAAA
TTTTATAATGTTCCTAAGAGCAAATGGACTTATCTTAGTCATAGGAGACT
TCAGAATTGGGGCGGTTTACCCGATCAAAAAGGAATGATACTGGAAGACA
TTCCAGAATGGGTCAATGAAATTATGACTAAAATTAATGATATTTCAATA
TTTGCGGATAATAATATTCAAACTAATCACGCCCTTCTCAATGAATACCA
ACAAGGGGAAGGAATTTTGCCCCATCATGACGGACCTTTGTACTATCCAA
TAGTAGCAACATTATCATTGAATTCACACACAGTTTTAAATTTTTACGAG
CCTCAATCCAATGATAAAATTATTCCTATCAATGAACGCAAAATTGCTCA
AGCCTTTATTGAGCCAAGAAGCCTTTATTTAATGAACGAAGACATTTACA
GTTATTTCATGCATGGCATTGATGAGGCTTTGTCGGATTTGATCGACGTT
GACAAATTTTGTAATATGGATTTTCTCGACAAGAAATATTCTAGCGAACT
TGCCAATCAAGAGCTTTCTAGATCAACTCGCGTTTCCTTTACTATTAGAA
ATGTTCCGAAAACTGTTAAACTGTCTAAGAGCTTTAAATTTAGATAAATA
AATATTTGAATGACT
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protein sequence of SMED30032268-orf-1

>SMED30032268-orf-1 ID=SMED30032268-orf-1|Name=SMED30032268-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=232bp
MSLSEFLIKTCPKSFYYIPNFIDKEKEKYLLNKFYNVPKSKWTYLSHRRL
QNWGGLPDQKGMILEDIPEWVNEIMTKINDISIFADNNIQTNHALLNEYQ
QGEGILPHHDGPLYYPIVATLSLNSHTVLNFYEPQSNDKIIPINERKIAQ
AFIEPRSLYLMNEDIYSYFMHGIDEALSDLIDVDKFCNMDFLDKKYSSEL
ANQELSRSTRVSFTIRNVPKTVKLSKSFKFR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR037151AlkB-like_sf
IPR032862ALKBH6
IPR027450AlkB-like
IPR005123Oxoglu/Fe-dep_dioxygenase
Vocabulary: molecular function
TermDefinition
GO:0016491oxidoreductase activity
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR027450Alpha-ketoglutarate-dependent dioxygenase AlkB-likePFAMPF135322OG-FeII_Oxy_2coord: 45..216
e-value: 3.7E-11
score: 43.6
IPR037151Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamilyGENE3DG3DSA:2.60.120.590coord: 2..226
e-value: 1.0E-41
score: 144.6
IPR032862Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6PANTHERPTHR46030FAMILY NOT NAMEDcoord: 1..224
IPR005123Oxoglutarate/iron-dependent dioxygenasePROSITEPS51471FE2OG_OXYcoord: 90..219
score: 8.241
NoneNo IPR availableSUPERFAMILYSSF51197Clavaminate synthase-likecoord: 13..219