death domain-containing protein 1

Overview
Namedeath domain-containing protein 1
Smed IDSMED30032215
Length (bp)2536
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of death domain-containing protein 1 (SMED30032215) t-SNE clustered cells

Violin plots show distribution of expression levels for death domain-containing protein 1 (SMED30032215) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of death domain-containing protein 1 (SMED30032215) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for death domain-containing protein 1 (SMED30032215) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032215

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30032215h1SMcG0000871 SmedASXL_015390SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30032215h1SMcG0000871 dd_Smed_v4_13807_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30032215h1SMcG0000871 dd_Smed_v4_13807_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30032215h1SMcG0000871 dd_Smed_v6_13807_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30032215h1SMcG0000871 dd_Smed_v6_13807_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Human
Match: DTHD1 (death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261])

HSP 1 Score: 81.2629 bits (199), Expect = 3.265e-15
Identity = 146/635 (22.99%), Postives = 273/635 (42.99%), Query Frame = 2 
Query:  710 RY-DLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGAR-----YVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSF---SPLLKIEGENRR-FLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANC-----DPS---------------GIEEKIYLL---TQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEV--VDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEI-IPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYV----TQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            RY D+ +   G Q + C+I A P +++ +  +   +IN +  +      EE+VSN+I I+ +   +++ +   P  + +P T     AR    +R  +  ++   ++ Q   +  N   G +        SV      I +VVS  K E     K+G    ++ DSR++   P G     + +++     D +LV  +K +      D  +S    SPL+ I+  +   F KPV++ LP     + KN+        GS  D + +A+       PS                  E + LL   +QDS   W      V        S++L  E    +I + + + +D S   +   ++++          +++SH  ++P+ I+V +  S  L + L+ L  EGF     + S+  +++E E L +RF GNI      +   +++     L+ K ++ L++  VD++   +   Y+G + +      K P+ ++   P  N   +I+     +PI +  L++PK +       S++    +SKD V       L        +E+ + L+  L L  + I+ IK  N +  + +E  +E L  W   LP   +K ++L + L  I R DL E+
Sbjct:    6 RYLDVLSDVTGPQ-VSCYITA-PSYVLQQ--LECRIINHMS-SLIVGDNEELVSNVITIECS---DKEKRVPFPIGIAIPFT-----ARYRGNYR--DIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQ-----DTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPC-SPYLDKNN-------LGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSG--WCGLDDVVKTIQSGLVSVEL-YEHLERFIVLHLSSTMDNS--HLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPP-EPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV-----YKVPKGKI--VPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKR---VSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRRSTIQLIKLKNPD--DLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEE 594
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Human
Match: DTHD1 (death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261])

HSP 1 Score: 80.8777 bits (198), Expect = 6.880e-15
Identity = 139/630 (22.06%), Postives = 268/630 (42.54%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGAR-----YVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSF---SPLLKIEGENRR-FLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANC-----DPS---------------GIEEKIYLL---TQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEV--VDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEI-IPIYEAMLEIPK----IQNSSTSKVSSRE---------FHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            + C+I A P +++ +  +   +IN +      D  EE+VSN+I I+ +   +++ +   P  + +P T     AR    +R  +  ++   ++ Q   +  N   G +        SV      I +VVS  K E     K+G    ++ DSR++   P G     + +++     D +LV  +K +      D  +S    SPL+ I+  +   F KPV++ LP     + KN+        GS  D + +A+       PS                  E + LL   +QDS   W      V        S++L  E    +I + + + +D S   +   ++++          +++SH  ++P+ I+V +  S  L + L+ L  EGF     + S+  +++E E L +RF GNI      +   +++     L+ K ++ L++  VD++   +   Y+G + +      K P+ ++   P  N   +I+     +PI +  L++PK    I    ++K  S++          H+++++   +            + + L+  L L  + I+ IK  N +  + +E  +E L  W   LP   +K ++L + L  I R DL E+
Sbjct:  309 VSCYITA-PSYVLQQ--LECRIINHMSSLIVGD-NEELVSNVITIECS---DKEKRVPFPIGIAIPFT-----ARYRGNYR--DIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQ-----DTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPC-SPYLDKNN-------LGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSG--WCGLDDVVKTIQSGLVSVEL-YEHLERFIVLHLSSTMDNS--HLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPP-EPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV-----YKVPKGKI--VPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEE------------NAESLSSTLPLRRSTIQLIKLKNPD--DLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEE 884
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Human
Match: DTHD1 (death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261])

HSP 1 Score: 80.4925 bits (197), Expect = 8.653e-15
Identity = 142/641 (22.15%), Postives = 273/641 (42.59%), Query Frame = 2 
Query:  716 DLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGAR-----YVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSF---SPLLKIEGENRR-FLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANC-----DPS---------------GIEEKIYLL---TQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEV--VDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEI-IPIYEAMLEIPK----IQNSSTSKVSSRE---------FHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            D+ +   G Q + C+I A P +++ +  +   +IN +      D  EE+VSN+I I+ +   +++ +   P  + +P T     AR    +R  +  ++   ++ Q   +  N   G +        SV      I +VVS  K E     K+G    ++ DSR++   P G     + +++     D +LV  +K +      D  +S    SPL+ I+  +   F KPV++ LP     + KN+        GS  D + +A+       PS                  E + LL   +QDS   W      V        S++L  E    +I + + + +D S   +   ++++          +++SH  ++P+ I+V +  S  L + L+ L  EGF     + S+  +++E E L +RF GNI      +   +++     L+ K ++ L++  VD++   +   Y+G + +      K P+ ++   P  N   +I+     +PI +  L++PK    I    ++K  S++          H+++++   +            + + L+  L L  + I+ IK  N +  + +E  +E L  W   LP   +K ++L + L  I R DL E+
Sbjct:  214 DVLSDVTGPQ-VSCYITA-PSYVLQQ--LECRIINHMSSLIVGDN-EELVSNVITIECS---DKEKRVPFPIGIAIPFT-----ARYRGNYR--DIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQ-----DTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPC-SPYLDKNN-------LGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSG--WCGLDDVVKTIQSGLVSVEL-YEHLERFIVLHLSSTMDNS--HLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPP-EPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV-----YKVPKGKI--VPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEE------------NAESLSSTLPLRRSTIQLIKLKNPD--DLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEE 799
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Human
Match: DTHD1 (death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261])

HSP 1 Score: 80.1073 bits (196), Expect = 1.157e-14
Identity = 139/630 (22.06%), Postives = 268/630 (42.54%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGAR-----YVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSF---SPLLKIEGENRR-FLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANC-----DPS---------------GIEEKIYLL---TQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEV--VDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEI-IPIYEAMLEIPK----IQNSSTSKVSSRE---------FHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            + C+I A P +++ +  +   +IN +      D  EE+VSN+I I+ +   +++ +   P  + +P T     AR    +R  +  ++   ++ Q   +  N   G +        SV      I +VVS  K E     K+G    ++ DSR++   P G     + +++     D +LV  +K +      D  +S    SPL+ I+  +   F KPV++ LP     + KN+        GS  D + +A+       PS                  E + LL   +QDS   W      V        S++L  E    +I + + + +D S   +   ++++          +++SH  ++P+ I+V +  S  L + L+ L  EGF     + S+  +++E E L +RF GNI      +   +++     L+ K ++ L++  VD++   +   Y+G + +      K P+ ++   P  N   +I+     +PI +  L++PK    I    ++K  S++          H+++++   +            + + L+  L L  + I+ IK  N +  + +E  +E L  W   LP   +K ++L + L  I R DL E+
Sbjct:  184 VSCYITA-PSYVLQQ--LECRIINHMSSLIVGDN-EELVSNVITIECS---DKEKRVPFPIGIAIPFT-----ARYRGNYR--DIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQ-----DTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPC-SPYLDKNN-------LGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSG--WCGLDDVVKTIQSGLVSVEL-YEHLERFIVLHLSSTMDNS--HLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPP-EPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV-----YKVPKGKI--VPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEE------------NAESLSSTLPLRRSTIQLIKLKNPD--DLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEE 759
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493])

HSP 1 Score: 56.225 bits (134), Expect = 2.727e-7
Identity = 53/219 (24.20%), Postives = 89/219 (40.64%), Query Frame = 2 
Query:  854 EEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMS-RTQARETKIFR-------------YFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDS 1468
            E +VS I+ +    +     KF  P  V +PH  + R + RE  + R             Y EDEL        +V     D    R    +  + P    VVS  K +       G   S+    +V    P+GA+   + + +      S LV++I          N  +FSP++ +E   R+F KP+++++P+P     K  S++ L  FG +  +
Sbjct: 1072 ESLVSRILQLGPPGT-----KFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKI--------LGNKATFSPIVTLEPRRRKFHKPITMTIPVP-----KASSDVMLNGFGGDAPT 1272
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Xenopus
Match: skiv2l (Ski2 like RNA helicase [Source:Xenbase;Acc:XB-GENE-486233])

HSP 1 Score: 90.8929 bits (224), Expect = 3.426e-18
Identity = 136/624 (21.79%), Postives = 275/624 (44.07%), Query Frame = 2 
Query:  707 FRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPM----ILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGEN-RRFLKPVSISLPLP-----QKQISKNDSNIPLTVFGSNTDSRSKANC----------DPS------GIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVD-ASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENEC-QVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQXXXX-XXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLME 2491
            +RY L      E  + CFI+A P +++ +  + V+ ++ I  +     +EE+VSNI+ I   LS + DL    P S+ +P + SR +     +     DE     +    +T    D     Y +  F E+ +    I +VVS  K E+    K+G +     D R++   P G  + ++ ++      D+S++  +K K    ++  + S SP++ ++  + + F KPV++ LP P     +KQ  ++D+    T  G      ++             +P+        +E  +++ +D   K V+N   +V FD          E  +++I + + + +D A        +E +  H  +  + VI+    ++     V +  S  L  ++ +L+EEG+     + S++++++E E +  RF GNI      +C +     +  Q K ++ + L VVD++   +   Y+G +++         +    GQ          +++  P+ +  + +PK++ + +   S++       D +   L+K       +ED   L  +L +  + ++ +K  + +  N +E  YE L  W   LP S +K ++L + L    R DL+E
Sbjct:   22 YRYMLQREGESEPTLACFIRA-PSYILQK--LQVQYMDSIS-SLMVSDSEELVSNILGI---LSLDSDLTIPFPLSISIPFS-SRYRGNYKDVMVKACDE----NLHPSYLTPHSLDGYHGNY-KGTFAEVKIYKLGIFSVVSCLKKENFTILKKGLSIKLGIDPRISLNYPPGCFRSSVIVQFKVQPIDTSIISLLKVKHDVYHS--VVSTSPMVHVKQPSVQLFRKPVTVFLPCPPNPEKKKQGEESDNKRASTAMGPRATGANQLRAVSAPMRKLGENPNESLKLLAYKEDQWIILEDIVVKNVQNG--IVSFDMD--------EHVTSFIVIRLSSAMDNAHLMSFIHSLE-VATHSSM--VNVILYRKKDNLQKAIVKVVPSKELTWEVANLREEGYSGPP-EPSEQIQLREGEQIHFRFCGNITASDGKDCGKTFGLTFHAQRKQRLSLHLSVVDEFGNYSCPHYKGTVAVYKLGKEDIAECYKSGQSTDT-----YLQQRSPVCKLAVTLPKMEKNVSRPSSTKIITSDPGDILWDSLLKWLAQELSEEDASHLVLSLPIRRSTVQLVKLKSPD--NLTEQIYEFLSFWKKSLPASADKIRLLARHLRKSGRSDLLE 609
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Xenopus
Match: nt5c1b (5'-nucleotidase, cytosolic IB [Source:Xenbase;Acc:XB-GENE-1009625])

HSP 1 Score: 73.559 bits (179), Expect = 4.585e-13
Identity = 92/415 (22.17%), Postives = 186/415 (44.82%), Query Frame = 2 
Query:  740 EQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPM----ILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGEN-RRFLKPVSISLPLP-----QKQISKNDSNIPLTVFGSNTDSRSKANCDPS--------------GIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNI 1912
            E  + CFI+A P +++ +  + V+ ++ I  +     +EE+VSNI+ I   LS + DL    P S+ +P + SR +     +     DE  + +  T       +   G  Y+   F E+ +    I +VVS  K E+    K+G +     D R++   P G  + ++ ++      D+S++  +K K    ++  + S SP++ ++  + + F KPV++ LP P     +KQ  + D+    T  G      ++A   P                 +E  +++ +D   K V+N   +V FD          E  +++I + + + +D +   +   + ++        + VI+    ++     V +  S  L  ++ +L+EEG+     + S++++++E E +  RF GNI
Sbjct:   30 EPTLACFIRA-PSYILQK--LQVQYMDSIS-SLMVSDSEELVSNILGI---LSLDSDLTIPFPLSISIPFS-SRYRGNYKDVMVKACDENLYPSYLT------PHSLDGGNYILGTFAEVKIYKLGIFSVVSCLKKENFTILKKGLSIKLGIDPRISLNYPPGGFRSSVIVQFKVQPIDTSIISLLKVKHDVYHS--VVSTSPMVHVKQPSVQLFRKPVTVFLPCPPNPEKKKQGEEADNKRASTAMGPRATGANQAVSAPMRKLGENPNESLKLLAYKEDQWIILEDIVVKNVQNG--IVSFDMD--------EHVTSFIVIRLSSAMDNA--HLMSFIHSLEVATHSSMVNVILYRKKDNLQKAIVKVVPSKELTWEVANLREEGYSGPP-EPSEQIQLREGEQIHFRFCGNI 415
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Match: Dthd1 (death domain containing 1 [Source:MGI Symbol;Acc:MGI:4937018])

HSP 1 Score: 82.4185 bits (202), Expect = 1.228e-15
Identity = 108/488 (22.13%), Postives = 218/488 (44.67%), Query Frame = 2 
Query: 1106 ILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRR-FLKPVSISL---PLPQKQI--SKNDSNIPLTV----------FGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEI-EKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVE---EFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQN-----SSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            + +VVS  K +     K+G TW ++ D+R++F+ P G     + +++     D SLV  +K     + +  + S SPL+ I+  +   F KPV++ L   PLP+K+   S+ D   P +           + + + S S      S  E    L  +  +  W      VV    +   +  E+ E    +I + + + VD S   +   ++++          +++SH  ++P+ + + +  S  L   L+SL+ EGF     + S++ +++E E L +RF GNI     N    E   + ++  Q K ++++ ++ VD++   +   Y+G +++          PR +  P  +   + +     P+ +  L++PK +       ST +VS+     +  + +     +          + LA +L L  + ++ IK  + +  + +E  +E+L  W   LP S +K ++L + L  + R DL E+
Sbjct:  308 MFSVVSCLKKQSFTVTKKGLTWKSSMDARISFSYPAGVFTSPVLVQLKIQPVDPSLVSYLKAHQDPSYS--VMSTSPLICIQHPSTHPFQKPVTVFLPCSPLPEKKNLESEKDHRRPESATVHRSLQTPSYFNRSKSPSLRKPGNSACETLKLLGFRSRDSGWFGIDDVVVR-TVQSGLVSFELCEHLERFIVLNLSSPVDNS--LLVSFVKSLEEASLSTTACIVLSHQKDNPHRVVILVVPSKELSLVLKSLRSEGFGGP--ESSRQFQVREGEQLLLRFTGNI-FGSSNGKDYEKDYKLIFHLQRKPRLELHIKEVDEFGNYSCPHYKGTITVYKV-------PREKIVPNLD-QTLHETFYQFPVCKLPLKLPKHEKVINRPQSTKRVSTDPLVALWDNLLHWLAEELAEEGA----EVLAASLPLRRSTVQLIKLKHPD--DPTEQIHELLCFWKRSLPTSTDKIRLLARHLRKMGRGDLTEE 773
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Match: Dthd1 (death domain containing 1 [Source:MGI Symbol;Acc:MGI:4937018])

HSP 1 Score: 82.4185 bits (202), Expect = 1.690e-15
Identity = 108/488 (22.13%), Postives = 218/488 (44.67%), Query Frame = 2 
Query: 1106 ILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRR-FLKPVSISL---PLPQKQI--SKNDSNIPLTV----------FGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEI-EKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVE---EFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQN-----SSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            + +VVS  K +     K+G TW ++ D+R++F+ P G     + +++     D SLV  +K     + +  + S SPL+ I+  +   F KPV++ L   PLP+K+   S+ D   P +           + + + S S      S  E    L  +  +  W      VV    +   +  E+ E    +I + + + VD S   +   ++++          +++SH  ++P+ + + +  S  L   L+SL+ EGF     + S++ +++E E L +RF GNI     N    E   + ++  Q K ++++ ++ VD++   +   Y+G +++          PR +  P  +   + +     P+ +  L++PK +       ST +VS+     +  + +     +      +     LA +L L  + ++ IK  + +  + +E  +E+L  W   LP S +K ++L + L  + R DL E+
Sbjct:  418 MFSVVSCLKKQSFTVTKKGLTWKSSMDARISFSYPAGVFTSPVLVQLKIQPVDPSLVSYLKAHQDPSYS--VMSTSPLICIQHPSTHPFQKPVTVFLPCSPLPEKKNLESEKDHRRPESATVHRSLQTPSYFNRSKSPSLRKPGNSACETLKLLGFRSRDSGWFGIDDVVVR-TVQSGLVSFELCEHLERFIVLNLSSPVDNS--LLVSFVKSLEEASLSTTACIVLSHQKDNPHRVVILVVPSKELSLVLKSLRSEGFGGP--ESSRQFQVREGEQLLLRFTGNI-FGSSNGKDYEKDYKLIFHLQRKPRLELHIKEVDEFGNYSCPHYKGTITVYKV-------PREKIVPNLD-QTLHETFYQFPVCKLPLKLPKHEKVINRPQSTKRVSTDPLVALWDNLLHWLAEELAEEGAEV----LAASLPLRRSTVQLIKLKHPD--DPTEQIHELLCFWKRSLPTSTDKIRLLARHLRKMGRGDLTEE 883
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 55.0694 bits (131), Expect = 5.310e-7
Identity = 54/216 (25.00%), Postives = 89/216 (41.20%), Query Frame = 2 
Query:  854 EEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMS-RTQARETKIFR-------------YFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSN 1459
            E +VS I+ +    +     KF  P  V +PH  + R + RE  + R             Y EDEL        +V     D    R    +  + P    VVS  K +       G   S+   S+V    P+GA+   + + +      S LV++I          N  +FSP++ +E   R+F KP+++++P+P     K  S++ L  FG +
Sbjct: 1057 ESLVSRILQLGPPGT-----KFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKI--------LGNKATFSPIVTLEPRRRKFHKPITMTIPVP-----KASSDVMLNGFGGD 1254
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 54.6842 bits (130), Expect = 5.770e-7
Identity = 49/196 (25.00%), Postives = 81/196 (41.33%), Query Frame = 2 
Query:  914 KFDQPFSVILPHTMS-RTQARETKIFR-------------YFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSN 1459
            +F  P  V +PH  + R + RE  + R             Y EDEL        +V     D    R    +  + P    VVS  K +       G   S+   S+V    P+GA+   + + +      S LV++I          N  +FSP++ +E   R+F KP+++++P+P     K  S++ L  FG +
Sbjct:  201 QFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKI--------LGNKATFSPIVTLEPRRRKFHKPITMTIPVP-----KASSDVMLNGFGGD 383
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 52.373 bits (124), Expect = 3.296e-6
Identity = 49/196 (25.00%), Postives = 81/196 (41.33%), Query Frame = 2 
Query:  914 KFDQPFSVILPHTMS-RTQARETKIFR-------------YFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSN 1459
            +F  P  V +PH  + R + RE  + R             Y EDEL        +V     D    R    +  + P    VVS  K +       G   S+   S+V    P+GA+   + + +      S LV++I          N  +FSP++ +E   R+F KP+++++P+P     K  S++ L  FG +
Sbjct:  985 QFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKI--------LGNKATFSPIVTLEPRRRKFHKPITMTIPVP-----KASSDVMLNGFGGD 1167
[Close]
BLAST of death domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q6ZMT9|DTHD1_HUMAN (Death domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DTHD1 PE=2 SV=3)

HSP 1 Score: 80.1073 bits (196), Expect = 5.558e-14
Identity = 139/630 (22.06%), Postives = 268/630 (42.54%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGAR-----YVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSF---SPLLKIEGENRR-FLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANC-----DPS---------------GIEEKIYLL---TQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEV--VDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEI-IPIYEAMLEIPK----IQNSSTSKVSSRE---------FHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            + C+I A P +++ +  +   +IN +      D  EE+VSN+I I+ +   +++ +   P  + +P T     AR    +R  +  ++   ++ Q   +  N   G +        SV      I +VVS  K E     K+G    ++ DSR++   P G     + +++     D +LV  +K +      D  +S    SPL+ I+  +   F KPV++ LP     + KN+        GS  D + +A+       PS                  E + LL   +QDS   W      V        S++L  E    +I + + + +D S   +   ++++          +++SH  ++P+ I+V +  S  L + L+ L  EGF     + S+  +++E E L +RF GNI      +   +++     L+ K ++ L++  VD++   +   Y+G + +      K P+ ++   P  N   +I+     +PI +  L++PK    I    ++K  S++          H+++++   +            + + L+  L L  + I+ IK  N +  + +E  +E L  W   LP   +K ++L + L  I R DL E+
Sbjct:  184 VSCYITA-PSYVLQQ--LECRIINHMSSLIVGDN-EELVSNVITIECS---DKEKRVPFPIGIAIPFT-----ARYRGNYR--DIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQ-----DTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPC-SPYLDKNN-------LGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSG--WCGLDDVVKTIQSGLVSVEL-YEHLERFIVLHLSSTMDNS--HLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPP-EPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV-----YKVPKGKI--VPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEE------------NAESLSSTLPLRRSTIQLIKLKNPD--DLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEE 759
[Close]
BLAST of death domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q01484|ANK2_HUMAN (Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4)

HSP 1 Score: 53.9138 bits (128), Expect = 7.886e-6
Identity = 53/216 (24.54%), Postives = 88/216 (40.74%), Query Frame = 2 
Query:  854 EEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMS-RTQARETKIFR-------------YFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSN 1459
            E +VS I+ +    +     KF  P  V +PH  + R + RE  + R             Y EDEL        +V     D    R    +  + P    VVS  K +       G   S+    +V    P+GA+   + + +      S LV++I          N  +FSP++ +E   R+F KP+++++P+P     K  S++ L  FG +
Sbjct: 1057 ESLVSRILQLGPPGT-----KFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKI--------LGNKATFSPIVTLEPRRRKFHKPITMTIPVP-----KASSDVMLNGFGGD 1254
[Close]
BLAST of death domain-containing protein 1 vs. TrEMBL
Match: K1S6Z0 (Uncharacterized protein OS=Crassostrea gigas OX=29159 GN=CGI_10027320 PE=4 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 2.199e-48
Identity = 163/605 (26.94%), Postives = 309/605 (51.07%), Query Frame = 2 
Query:  740 EQGI-GCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLP--QKQISKNDSNIPLTVFGSNTDSRSKANCDP-SGI---------EEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASP---EQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQ----MIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            E G+ GC I+A+ G M    D+ V+ ++ +    +    EE+VSNI+ I  +  E +  +F++P SV +PH + R       + +  +   +W  + T D+ IED      ++VE       +   V+ I K + L + +RG   +++ D+R++FT   G VK N+       A D + V E+  K   T   ++ S SP+++ +  NR+F KP++ +LPLP    ++ +  S  P ++     + R +A   P S I         EE+++LL ++    W       +   + KD +  +I++  +  F+ +R K   SP   E++A  +E  ++H   R ++V++   ++DPN + +  C +SR DK ++ L EEGFD+     S+++ +KE +IL + FRGNI+    ++ +    +++T ++ + +  +E +DK+AQ++ S Y GF  + T+   ++P   V G  +   PQ    M  VEE + + E ++ IPK +      +++      ++    + +++ ++ ++ ++WK LA+ L L + RI+ I   N       ++ Y++L  W   +P   NK +IL +AL +  R DL  D
Sbjct:  852 EAGVPGCVIRAIEGSM-KRDDVTVKAVDQLSGVLTLVENEELVSNIVSITPSDPERK-FQFEEPVSVAIPHCLQRNIPGREPVIKQLQPTGKWAELPTNDIVIED--MREMKFVEIRVKRFGVFAIVLRIKK-DTLTFLRRGNKVNSSVDARISFTCKPGMVKNNVCFTSEVQALDVNTVTEL-NKRYPTECGSLLSSSPIVRFQIPNRKFAKPLTFTLPLPPNSTKLKRPQSVAPGSLNKDKGEHREQAAARPLSSIGFSTKEDEPEEEMHLLVREDKGPWTIQPNVELFQPKNKDIVTFDIKEPHDR-FIILRTKQGISPLSVEKMASHVERAIHH---RTMQVVLRQRSDDPNEVVIVCCPASRTDKTIKILGEEGFDE-GPPPSKDIIVKEGQILDIMFRGNIRC---DDAEKISIVFNTFIRGRTEFNVEEIDKFAQKSFSFYRGFAQVYTTVHVQRP---VVGTDKTKAPQKPGAMEVVEENVLLTELLINIPKPEPEPPKPLATAPIKVTAEGPNKEDILQYVASELGDEWKKLAQYLSLKSVRIQAILRQNNQNPEPKKIRYDMLVTWAKRVPRCLNKLEILAQALSACGRGDLAID 1439
[Close]
BLAST of death domain-containing protein 1 vs. TrEMBL
Match: V3ZPR4 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_232757 PE=4 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 7.389e-48
Identity = 164/619 (26.49%), Postives = 307/619 (49.60%), Query Frame = 2 
Query:  704 KFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSR-TQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLP--------------QKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTS----KWTKKPQPRVEGQPRKNPP----QMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLME 2491
            ++ Y + + +F   GIGC I+++ G +    DI V  I+ I   Y     EE++SNII +K    +N  L+F++P S+++PH   R T  RE  +  Y +    W  + T DV  +D      R+VE+   +L   + V  + K E   + K+G   S+  DSR   T   GA + NL +       DS+ V E++ +        + S S +     +N R  KP++I+LP P              +++++K D+  P T   +   S    + D + +EE+++L+ +D+   W+     V+   + KD I L+I +     F+ +R K+D +  Q  K +  +      R I++ +  + ED N I VS  ++++++K L+ L EEG+D+    +S+++ ++E ++L +RFRGN+    E+  ++    +++ + ++I   +E +DK+AQR    Y GF  + T     K  ++ + R  G+ R NP     +M++ E  I + E ++ IPK +      +         +  V + + + +S ++ ++W+ LA+ L++   RI+ I   N N +   +  Y++L  W   +P + +K ++L  AL    R DL+E
Sbjct:  721 RYIYSIESEDFN-PGIGCIIRSIKGSL-DRDDIEVNRIDQITGGYQIHENEELISNIIVVKQMTDKN--LEFEEPLSIVMPHCAPRSTTGREPVMKCYDDTAANWVELQTNDVMFDD--IKDLRFVEARVTKLGKFVVVYRLKK-EQFTFTKKGGKQSSTVDSRFTLTTKPGAFRYNLGVSTEIQPVDSNTVSELRQRDNEICGALLASTSIITMTWKQNTRLSKPITITLPCPPNPARIKRPSTAVNREKVAKQDAR-PQTARPA---SEYFKHTDDAKLEEELHLVIKDNTSGWLTVPDVVITQAKNKDIISLDITEPITR-FVVLRTKMDLAEYQAEKMVSRLEKALLQRTIQLFLRQNTEDLNEILVSCANTNKIEKVLKRLDEEGYDE-GPPLSKDIIVREGQVLELRFRGNLAPVTEHRTKI---AFNSHINSQITFRVEELDKFAQRGFDSYRGFCQVFTDGLVPKVIQEQEERDTGKGRNNPKNTHVEMVEGE--ILLGELLMNIPKPEPEPPRPLVKAPVSIKPEGPVNEDVFRFISREVGDEWRKLAQYLNVRRMRIQAILRQNVNSER-QQTIYDMLVSWAKRVPRAMDKVEMLCHALSVCGRGDLVE 1320
[Close]
BLAST of death domain-containing protein 1 vs. TrEMBL
Match: R7UT39 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_221873 PE=4 SV=1)

HSP 1 Score: 194.897 bits (494), Expect = 1.191e-47
Identity = 157/599 (26.21%), Postives = 296/599 (49.42%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSK------ANCDPSG------IEEKIYLLTQ-DSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQP---RKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSR-EFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            IGC ++ +     S  DI VE ++ +      DG EE+V NII +  T         ++P ++ +PH   R  A    + +  +++  WT + T++VTI  +D    ++VE         LTVV+  + E     KRG   +++ DSRV F+  Q   + +  + +     DS+ V ++K +      DN+ + SP+L  E  N++  KP ++SLP+P    + +    P+T        R+       A+  PS        E+++++LTQ + + +WV  S   +   + +DS+  +  +  + + + +R K + +  Q  K +  I      R  ++++  H++D   + +      R+++  R L E+GF +    +SQE+ + E ++++V+FRGN+++ ++ E  V +F+Y++ +K  +   +  +DKYAQ+    Y GF  + T     K     E +    +K  P++  VEE I + E ++ +PK +  S   + +R    F S   V   +++ L+ ++ E+W+ LA+ L++   RI+ I   N N  +S ++ Y++L  W   +P S NK  IL  AL    R DL+E+
Sbjct:  319 IGCVVRVMEEG-CSRGDINVEQLDQLTGIVQLDGVEELVGNIIQLTQT-DPKMTFNLEEPLAIAIPHCAPRNVASREPVVKSLQEDGTWTELPTREVTI--DDMKEYKFVEVRLPNPNATLTVVTRTRRETFTIQKRGGKVNSSVDSRVCFSFKQSTFRTSSDITLEVQTIDSATVHDLKVRHADV-CDNLLTTSPILCCEISNQKTYKPFTMSLPVPP---NPHKPRRPVTAMDRPDQKRAASGKPRPASAMPSAYQKEETAEDELHILTQAEDSDEWVRASDIQLTQSKNRDSVMWDTRRPPHRVIV-LRTKPETTGPQAEKIVRQIEVTLTQRVTQLVLRQHSQDAGNVLIQCSDVHRMERTTRKLTEQGF-EHGPALSQEIIMGEGQVISVQFRGNLQMSQQEE-PVTKFVYNSHIKACLNFDVMEIDKYAQKGIDCYRGFAQVFTRGLVPKVLDVDEDKTIRNKKGGPRVEMVEEDIMLCEMLISLPKPEPESPKPIVNRVPVKFNSHGLVGNDILRHLASEVGEEWRRLAQCLNIRRARIQAIVRNNVN-SDSEQVIYDMLLTWAKKVPRSMNKVDILCHALMQCGRSDLVEE 905
[Close]
BLAST of death domain-containing protein 1 vs. TrEMBL
Match: A0A210QUR4 (Death domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT06862 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.636e-42
Identity = 153/617 (24.80%), Postives = 288/617 (46.68%), Query Frame = 2 
Query:  713 YDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQK------------QISKND-------SNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIP----IYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            Y     +F + G+GC ++A+   +    D+ V  ++ +    +    EE++SNII I  T +E     F++P ++ +PH + R  A    + +      +W  + T+D   ED      R+ E+      +   V+ + K + L + ++G     A D+RV+FT P G  K N +  +     D + +  +K K       N+ + SP++K   +NR+F K ++++LP+PQ                K D       +  PL  F +N +   +          +++LL  +    W + +   +   + KD + +E+++  +  F+ +R  +   P ++      +      R I V +   N + N ++V     S+ +K+L+ L  EG+DD     S+E+ +KE +++ + FRGN+    EN   V +F+Y+T +K+K++  +   D++AQ+  + Y GF  + T+    KP P     P   P Q   V E+I     + E ++ IPK +      + +      ++   TQ ++  L+ ++ E+WK LA+ L+L + RI+ I   N    +  ++ Y++L  W   +P S NK  IL  AL +  R DL E+
Sbjct:  934 YSADGGDF-DPGVGCILRAIDNCL-GRDDVNVVRVDQMSGVLTLVDNEELISNIIKITPTDAERR-FTFEEPVALAIPHCLPRAVAGREVVVKTRSANGKWVELPTKDAVFED--MKEMRFGEAQTRRFGVFAVVLRLKK-DTLTFVRKGNKVHTAVDARVSFTSPPGMFKTNTNFTVEVQQIDQTAIASLKHKHP-VECGNLMACSPIMKFSIQNRKFNKTLTMTLPIPQNPTRPKRPSTAVASAPKEDKSEQRPVTARPLVSFNANKEEEIEE---------ELHLLVCEEGCLWTKLADVSIVQAKNKDIVTVEVKEPHDR-FLVIRTGLGVGPAKLETAATLLDRSVTQRSINVFLRQLNTNLNQVAVGSSKISKTEKELKKLAAEGYDDGPAP-SREIVVKEGQMIRLAFRGNVHCTTEN--AVLQFIYNTHIKSKVRFSILETDRFAQKGFNCYRGFSQIYTNVLVPKPVP-----PTDKPKQKQTVAEMIEEEKLVAELLMSIPKPEPEPPKPLCTAPIKINAEGPDTQDVLMYLAGELGEEWKKLAQYLNLKSVRIQAILRQNNMNPDPKKIRYDMLVTWAKRIPRSANKMDILAHALLASGRGDLAEE 1525
[Close]
BLAST of death domain-containing protein 1 vs. TrEMBL
Match: A0A1S3HDZ3 (death domain-containing protein 1 OS=Lingula unguis OX=7574 GN=LOC106153746 PE=4 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 1.986e-41
Identity = 153/611 (25.04%), Postives = 302/611 (49.43%), Query Frame = 2 
Query:  707 FRYDLANSEFGEQGIGCFIKALPGFMV--SESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFE-DELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNI-PLTVFGSNTDSRS------KANCDPSGIEEKIYLLTQ-DSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKK-----PQPRVEGQPRKNPPQMID-VEEIIPIYEAMLEIPKIQNSSTSK-VSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDL 2485
            +RY+    +F + GI   ++++P  M    E  +  + +N +    +    EE+VSNI+ I  + SE    KF++P +V +PH   +  +RE  + +Y E  + +W  + +Q++ ++D     A++V+           VV+  K++ L  NK+    S+  D R+      G V    +  +     DS  + E+K +    +   + + SP+++ +    +F KP+ +++P P    +K      P    G +T   S      K   +   +E+ ++LLT+ + ++ W+  +   +   +KKD++  EI K  +  FM +R K  A   +  K    I    + R ++ ++   ++DP+ +S+   +++++DK LR + EEGFDD     S++L + E + L +RFRGNI+   E+E ++  F +++QLK+ + I +  +DK+AQ++   Y GF+ + T    K+      + R     +  P + +  V   I + E ++ +PK +  +    V      F+    V + +++ ++  + ++WK +A  L++  +R++ I   N N  N   + Y++L  W   +P S +K ++L KAL S  RPDL
Sbjct:  314 YRYNEEQIDF-DLGIMAVVRSMPWTMDPDDEESLQCKKLNQLDSTLTIAENEELVSNIVEIVPS-SEKVVFKFEEPLAVAIPHCAQKVSSRELAV-KYLETGKDKWRELPSQEIILQD--LREAKFVQCRLKTFGQ-FAVVTRLKLDRLVPNKKDGKMSSTVDQRLVLHCRPGTVPSTATFGLQVQPVDSFAISELKVRL-SEDCGPLLTCSPIVRFQCSTSKFKKPIQVTIPCPPNPKAKRPQTARPKEKEGKSTRPSSAFSLGLKQKAEDDDLEDTVFLLTRTEGDEGWIVMADIDISESKKKDAVIFEITKPYDR-FMALRLKHGAGGMKAQKLANLIETALQKRTVRAVLRQKSDDPSDVSLQCLAANKIDKALRKMTEEGFDD-GPPASKDLVLTEGQELFLRFRGNIQC--EDEEEILNFCFNSQLKSGVNIYVTEIDKFAQKSLDCYRGFVQVYTKGMIKQIIKKENEDRDAVGGKSGPKEEVTWVMGDILLCELLVSLPKPEPEAPKPLVQKAPVTFIPDGPVDESVLRNIATDLGDEWKKVAHILNIRKSRVQAILRNNVNSDNEVAI-YDMLITWAKKVPRSMDKVELLGKALTSAGRPDL 912
[Close]
BLAST of death domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003269.1 (pep scaffold:Pmarinus_7.0:GL476625:60944:70653:1 gene:ENSPMAG00000002987.1 transcript:ENSPMAT00000003269.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 7.361e-14
Identity = 89/470 (18.94%), Postives = 200/470 (42.55%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINY--SFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTM--SRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADN-IFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPL--TVFGSNTDSRSKANC---DPSGIE-----------EKIYLLTQDS-NKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRF--RGNIKLKK----ENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTK 2074
            + C I+  P  ++ +  ++  L +  + +   S D  +E++S+++ +     + +  +  Q  +V +P+T+   R+ A E  + + +    +W  +  + +     D+    + E    ELP I  V+ +   E L  +K G ++ ++ D R+   +P+   K ++ + +       ++V  ++T     +AD  + + SP++ + G  R F++P+ + LP P+  +      +P   +  G +  S +   C     +GIE           E + L+ Q +    W E S   +    K DS+++E+ +    + +   A            +E + +    RQ  V+   H  D   ++V  C+ S L++   +L++ GF       S      E + L + F   GNI   +     ++ + +   +     +++++ L   D +A R    Y G L + ++  ++
Sbjct:    3 VACLIRG-PQHLLEDLGVSCYLSDRYQHHQQQSEDDYQELLSHVLCL-----QPKGQRLSQAVTVCVPYTVRGPRSLAGEV-VGKIWRGGAQWEVILPKALDCVYPDSEDDVFAEFSLHELPTIAVVLRLTN-EHLLVDKEGGSFKSSVDPRILLNVPKDFTKSSVQLSLQVQPVPVAVVASLQTARDPADADACLIATSPIVSLGGAAR-FMRPLVLVLPCPRFAVGVRARTVPTVSSHVGRSGRSVNILTCQLFSKTGIELTTRHIRKQDDEVLRLVAQPTVGGHWTELSDVGI-LSRKSDSVQVELHRPVRRLLLLRLAARSRGVAMAGAVIEAVRS----RQAVVLAQRHGADAGRLAVVCCALSGLEEAEEALQKAGFSGPP-GPSHPFPAHEGQELYLHFTSTGNIMAIRTGVSNDDGKEQRLTFHAHRHSRLQLRLRERDPFANRGHQNYRGALHVMSTPASR 457
[Close]
BLAST of death domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000008533.1 (SMESG000008533.1)

HSP 1 Score: 1343.18 bits (3475), Expect = 0.000e+0
Identity = 734/740 (99.19%), Postives = 737/740 (99.59%), Query Frame = 2 
Query:   35 MDXXXXXXXXXXEEINRYLSIETIDKFLGISKDSEKELEDVKIVLQEYISEISSDETSLTELTVLIHELTILVSKKFQQFNNENSRSIAEGSSINS-DFMEKLELDKAQLKLKYLENSVSFQRMLETLNVVNDKIIEIEKCFAEVTIQEKLCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIQRANEAALEAKLRQQXXXXXXXXXXXXXXXXXXXXXHFIKFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQ 2251
            MDKLKQSKLKLKEEINRYLSIETIDKFLGISKDSEKELEDVKIVLQEYISEISSDETSLTELTVLIHELTILVSKKFQQFNNENSRSIAEGSSINS DFMEKLELDKAQLKLKYLENSVSFQ+MLETLNVVNDKIIEIEKCFAEVTIQEKLCQEKLIEKERLIEEQKKQKEHNEEIRKEEEQKVIQRANEAALEAKLRQQEIDKMKKIIEEENKSPEENIEHFIKFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGC+WSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDAS EQIAKGME IMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEA+LEIPKIQNSSTSKVSSREFHFMSKDYVTQ
Sbjct:    1 MDKLKQSKLKLKEEINRYLSIETIDKFLGISKDSEKELEDVKIVLQEYISEISSDETSLTELTVLIHELTILVSKKFQQFNNENSRSIAEGSSINSEDFMEKLELDKAQLKLKYLENSVSFQKMLETLNVVNDKIIEIEKCFAEVTIQEKLCQEKLIEKERLIEEQKKQKEHNEEIRKEEEQKVIQRANEAALEAKLRQQEIDKMKKIIEEENKSPEENIEHFIKFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCSWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASLEQIAKGMEIIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEALLEIPKIQNSSTSKVSSREFHFMSKDYVTQ 740
[Close]
BLAST of death domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000048822.1 (SMESG000048822.1)

HSP 1 Score: 210.305 bits (534), Expect = 6.655e-57
Identity = 168/608 (27.63%), Postives = 298/608 (49.01%), Query Frame = 2 
Query:  704 KFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTT---LSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGE-NRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNT---DSRSKANCDP--SGIEEKIYLLTQ--DSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDLMED 2494
            +FRY L    F E  +   I+A    +    D++V L     I+       +I+SNII I+     +S N  L    P+ + +P+++ R+  RE  IF   E + R+  ++TQD+  E++   G ++ E+       +  VVS  K+E  + NK+  T  +  D R++ TIP  ++ + + M+      +S L+ EIK K K    + + S SP+++I  E  R+ LKP+++ LP+P       + N   +   S T   D R K       S     I  L Q  +++K W          ++  DS+ +E++K        +R   + S E++ K +E I    + R ++ I +   E+ N + + +   ++++K  + L E+ ++D+   IS EL ++ER+   + FRGNI+    +E  V    Y++QL N+++  ++  DK+AQ+ K  Y+G++S+  S  T                  +D      ++E ++ IPK +N   + +  ++F F   D + ++ +  LS +I EDWK L  AL +P   I  I   N  ++  S M Y+ L  WI +LPV  NK ++++KAL  I R DL++D
Sbjct:  234 RFRYSLRGGYFHETELVYMIQAFKDTLDQCYDVSVTLDKLEDISDGLGYYYDILSNIIRIEPVGLEVSFNAKL----PWKISIPYSIIRSPNREVVIFCKDESQQRYFELETQDILYEESREEGIKFAEASLPSPNCLCVVVSKRKVERFEINKKAITIESKVDDRISLTIPPSSIMIPIPMQFVVQPIESGLINEIKLKLKTPVLNGVQSVSPIIEINSELERKLLKPITLQLPIPFPTGYVPNKNRIFSAAPSTTEKNDRRPKTALTRQISNESNSIIKLAQYSETDKVWRVQRDYKPVLNKNGDSMSIELQKLEKQKLAAIRCTEEVSDEKVQKALEIIEESSENRLVQFICAQKIENANRLILLISPPNKVEKLQKLLLEQNYNDETMSISSELNVRERDKFIINFRGNIESVTRSELMV---TYNSQLPNRLEFFVQEKDKFAQKNKDSYQGYVSVLKSGET-----------------FLD-----KLWEIVIFIPKFENERNNSL-HKDFDFKPTDTINKEYLHYLSHQIGEDWKHLGYALRVPDETIRRIA--NDTREEMSSMTYQCLLKWIKNLPVYSNKVELMEKALKYIGRNDLVKD 809
[Close]
BLAST of death domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000031073.1 (SMESG000031073.1)

HSP 1 Score: 147.517 bits (371), Expect = 9.504e-36
Identity = 149/612 (24.35%), Postives = 280/612 (45.75%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKV--NLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLP-------QKQIS----------------------KNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLT-QDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHF-MSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDL 2485
            +GC +KA PG +   ++     I   +I  + D  E+  S  I IK T   +++  F+ P+ +ILPH + +   ++  I    +D+  W  + T ++ ++D      R+VE+  ++   I  V +  + ++   NK G   +++ DSRV  ++P GA+++  N ++KI TV  DSS  +E+K K   +  + +   S L+    + ++ +KP  IS  LP       Q+++                       +N S IP     +   S   +    +   E I +L   +   KW E  +  +  D+ K+ + LE     +  F  +RA    + E + KG++ I   F LR   +I+    ++P    +  C  SR +K +   K++G++ +       +E+KER+IL   F GNI+    ++     F Y +   N      + +D YAQRA   Y G++ + T K  KKP    + + RK   Q   VEE   I + ++ IPK    +   + +  F+  + +D++         + I   WK L  +L +  +R++ +K  N   +   ++  ++L  W   L +  +K ++L+++L  ++R DL
Sbjct: 2795 MGCILKAKPGGIGRHTNFECSSIYSSRILPNIDLQEDAASIPIEIKPT-DPSQEFNFENPWKLILPHILPKNSPKDPVILMLSDDDTGWIEMPTSEIILDDLKEHKLRFVETKLEKRSGIFIVQTKNRTDNGIINKHGARIASSMDSRVFVSVPAGAIRITLNTTLKINTV--DSSFWKELKGKFDKSPLEQVICSSHLIAFTSKKKKLIKPAIISCHLPLNAEVKKQQEVQPKTTTKKKDRAEDDEDDDNGDKQNKSFIPKIEMNAFQKSLLMSGISGANANESIKVLVYSNEEDKWNEMEKPEISTDKTKEQMSLEFPTIQSTKFFMLRANRTITFENLTKGVKLIETEFSLRNSLIILLKSAKNPYEFILLTCLKSRSEKIISQFKDDGYNVEPQNTPVSIELKERQILRTSFSGNIQNVNPDK-NTMFFAYQSLFLNLQIFRTKPIDTYAQRAIDHYRGYIMVFTKKLMKKPIESADKKARKGHVQYQMVEEDFMICQLLISIPKKGLIAHKPLRNIPFNREILEDFLCMFTRIADGIGIS--WKELGTSLKISESRLQMLKHHNPGNQ-PGKIVIQMLLFWFKGLELMDDKTEMLRQSLLEVNRNDL 3399
[Close]
BLAST of death domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000031073.1 (SMESG000031073.1)

HSP 1 Score: 147.517 bits (371), Expect = 1.138e-35
Identity = 149/612 (24.35%), Postives = 280/612 (45.75%), Query Frame = 2 
Query:  749 IGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKV--NLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLP-------QKQIS----------------------KNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLT-QDSNKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFDDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHF-MSKDYVTQXXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDSIHRPDL 2485
            +GC +KA PG +   ++     I   +I  + D  E+  S  I IK T   +++  F+ P+ +ILPH + +   ++  I    +D+  W  + T ++ ++D      R+VE+  ++   I  V +  + ++   NK G   +++ DSRV  ++P GA+++  N ++KI TV  DSS  +E+K K   +  + +   S L+    + ++ +KP  IS  LP       Q+++                       +N S IP     +   S   +    +   E I +L   +   KW E  +  +  D+ K+ + LE     +  F  +RA    + E + KG++ I   F LR   +I+    ++P    +  C  SR +K +   K++G++ +       +E+KER+IL   F GNI+    ++     F Y +   N      + +D YAQRA   Y G++ + T K  KKP    + + RK   Q   VEE   I + ++ IPK    +   + +  F+  + +D++         + I   WK L  +L +  +R++ +K  N   +   ++  ++L  W   L +  +K ++L+++L  ++R DL
Sbjct: 2763 MGCILKAKPGGIGRHTNFECSSIYSSRILPNIDLQEDAASIPIEIKPT-DPSQEFNFENPWKLILPHILPKNSPKDPVILMLSDDDTGWIEMPTSEIILDDLKEHKLRFVETKLEKRSGIFIVQTKNRTDNGIINKHGARIASSMDSRVFVSVPAGAIRITLNTTLKINTV--DSSFWKELKGKFDKSPLEQVICSSHLIAFTSKKKKLIKPAIISCHLPLNAEVKKQQEVQPKTTTKKKDRAEDDEDDDNGDKQNKSFIPKIEMNAFQKSLLMSGISGANANESIKVLVYSNEEDKWNEMEKPEISTDKTKEQMSLEFPTIQSTKFFMLRANRTITFENLTKGVKLIETEFSLRNSLIILLKSAKNPYEFILLTCLKSRSEKIISQFKDDGYNVEPQNTPVSIELKERQILRTSFSGNIQNVNPDK-NTMFFAYQSLFLNLQIFRTKPIDTYAQRAIDHYRGYIMVFTKKLMKKPIESADKKARKGHVQYQMVEEDFMICQLLISIPKKGLIAHKPLRNIPFNREILEDFLCMFTRIADGIGIS--WKELGTSLKISESRLQMLKHHNPGNQ-PGKIVIQMLLFWFKGLELMDDKTEMLRQSLLEVNRNDL 3367
[Close]
BLAST of death domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000073578.1 (SMESG000073578.1)

HSP 1 Score: 141.739 bits (356), Expect = 4.346e-34
Identity = 151/620 (24.35%), Postives = 284/620 (45.81%), Query Frame = 2 
Query:  704 KFRYDLANSEFGEQGIGCFIKALPGFMVSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFSVILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVESVFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNLSMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVSISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDSN-----------------------------KKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKGMETIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGF--DDKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIKIPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDVEEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQ-XXXXXXXXXXXXDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKNKDKILKKALDS 2467
            K  Y +      ++ + C I+A PG +V + ++  EL+N  +     D  E   S I  I    SE +  +F+ P+ + +P+     + +E  I    E+  +W    T +V+ ++   +   +VE+   +   I  VVS    + +  +K G   +  +D  V+F++PQ ++K++++  I  V+ D+   +EIK K   +  D I   S +++IE + ++   P S+++ L    +   D N+      +N D   K       +E+KI  L ++ N                              +W    +  + F+  K+ + ++I+   +  F+ +++K + + E + K  + I N F +R   + +    +  N  ++ +         ++ L EEG+  D +N  +   +E+ ER+I+T +F  N+K    N  Q   F + T L N  K  ++ +D +AQRA   + G+L+L  +   +KP    E + RKN  Q   VEE I I   ++ I K +   +   S  ++HF  K+Y T   +IK++S KI  +W  L   L +   R++ IK L+   +  ++MA  +L  W+      +NK  +LK AL S
Sbjct:  526 KHYYYIKPPNLYDKTLACVIRAKPGSIVKKKNLKCELLNSEEEIPYLDKRENYASYIFKISPIDSEAQ-FQFETPWHLAIPYYPLLNKVKEPIIMIKNEELNKWMESPTSEVSFDNEKQNVLNFVETKIFKPNGIFAVVSSLCKDVIVISKEGNQITCISDRNVSFSVPQDSLKISITTCIQVVSIDNLFWKEIKEKHGKSLLDQINFTSSIIEIEAKKKKLTIPASLTMKLLDNVVKDQDVNLKKEKKETNEDEDVK-------LEDKILTLKKELNPFQKTLLMEKINNTNAIRDIHLLNYLHEEDRWFVTKENALIFNSNKNQVSIQIQILQSSKFIILQSKRNTNEETLTKVAKLIENEFCVRNCIIALFQSAQIQNQFALIISLKKYFQNNIKVLLEEGYILDSRNDLV--HVELHERQIITSKFVENVKNINHNTFQ-SLFTFHTLLPNIHKFKVQELDSHAQRAVLTFRGYLNLYITSLVRKPINNTESKIRKNQIQYTWVEENIMISHFLICINKKKIPLSP--SFIDYHFKFKNYKTCFTIIKKISGKIGYNWWDLGLHLGVTETRMQSIK-LHNETRGINKMAENMLLFWLKGCETQENKLDLLKTALRS 1131
The following BLAST results are available for this feature:
BLAST of death domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DTHD13.265e-1522.99death domain containing 1 [Source:HGNC Symbol;Acc:... [more]
DTHD16.880e-1522.06death domain containing 1 [Source:HGNC Symbol;Acc:... [more]
DTHD18.653e-1522.15death domain containing 1 [Source:HGNC Symbol;Acc:... [more]
DTHD11.157e-1422.06death domain containing 1 [Source:HGNC Symbol;Acc:... [more]
ANK22.727e-724.20ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493][more]
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BLAST of death domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
skiv2l3.426e-1821.79Ski2 like RNA helicase [Source:Xenbase;Acc:XB-GENE... [more]
nt5c1b4.585e-1322.175'-nucleotidase, cytosolic IB [Source:Xenbase;Acc:... [more]
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BLAST of death domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dthd11.228e-1522.13death domain containing 1 [Source:MGI Symbol;Acc:M... [more]
Dthd11.690e-1522.13death domain containing 1 [Source:MGI Symbol;Acc:M... [more]
Ank25.310e-725.00ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025][more]
Ank25.770e-725.00ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025][more]
Ank23.296e-625.00ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025][more]
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BLAST of death domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q6ZMT9|DTHD1_HUMAN5.558e-1422.06Death domain-containing protein 1 OS=Homo sapiens ... [more]
sp|Q01484|ANK2_HUMAN7.886e-624.54Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=... [more]
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BLAST of death domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1S6Z02.199e-4826.94Uncharacterized protein OS=Crassostrea gigas OX=29... [more]
V3ZPR47.389e-4826.49Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
R7UT391.191e-4726.21Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A210QUR41.636e-4224.80Death domain-containing protein 1 OS=Mizuhopecten ... [more]
A0A1S3HDZ31.986e-4125.04death domain-containing protein 1 OS=Lingula ungui... [more]
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BLAST of death domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000003269.17.361e-1418.94pep scaffold:Pmarinus_7.0:GL476625:60944:70653:1 g... [more]
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BLAST of death domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of death domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008533.10.000e+099.19SMESG000008533.1[more]
SMESG000048822.16.655e-5727.63SMESG000048822.1[more]
SMESG000031073.19.504e-3624.35SMESG000031073.1[more]
SMESG000031073.11.138e-3524.35SMESG000031073.1[more]
SMESG000073578.14.346e-3424.35SMESG000073578.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032215 ID=SMED30032215|Name=death domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2536bp
GCTTAGTGCAAAATAACTAGAAAATTTTGATAGAATGGATAAGTTAAAAC
AATCAAAATTAAAGCTAAAAGAGGAAATAAACCGATATTTATCAATTGAA
ACAATAGACAAATTTTTGGGCATTAGTAAGGATTCCGAAAAAGAATTGGA
AGATGTCAAAATAGTTCTTCAGGAATATATCTCTGAAATTAGTTCAGATG
AGACAAGCTTAACTGAACTCACAGTGCTCATACATGAGTTGACCATTTTG
GTGTCGAAAAAATTTCAACAATTTAACAACGAAAATTCTAGATCCATTGC
TGAAGGAAGCTCAATAAATTCAGACTTTATGGAAAAACTTGAACTGGACA
AAGCACAATTGAAATTAAAATATTTGGAAAATTCCGTCTCTTTTCAAAGG
ATGTTAGAAACTTTAAATGTAGTCAATGATAAAATTATTGAAATTGAAAA
ATGCTTTGCTGAAGTGACTATCCAAGAAAAGTTATGCCAGGAAAAATTGA
TTGAGAAAGAAAGATTAATTGAAGAGCAGAAAAAGCAAAAAGAACACAAC
GAGGAAATCAGAAAAGAGGAGGAACAAAAGGTAATTCAAAGAGCAAATGA
AGCGGCTTTAGAGGCTAAATTAAGACAACAAGAAATTGATAAAATGAAAA
AGATTATTGAAGAAGAAAACAAAAGTCCCGAAGAAAATATTGAACATTTT
ATTAAATTTAGATACGATTTGGCGAATAGTGAATTCGGTGAACAAGGAAT
TGGATGCTTTATTAAAGCTCTTCCTGGTTTTATGGTCTCTGAATCAGATA
TAGCGGTCGAGTTGATAAATCCAATAAAAATAAATTATAGTTTTGATGGA
ACGGAGGAAATTGTCAGTAATATAATTCATATTAAAACAACGTTAAGTGA
AAATGAAGATTTAAAATTCGATCAACCTTTTTCAGTGATTTTGCCTCATA
CAATGTCTCGAACTCAAGCCCGAGAAACCAAAATATTTAGATATTTCGAA
GATGAGTTACGATGGACTGCAGTGGATACTCAAGACGTAACTATTGAGGA
TAACGATACATCTGGAGCGCGATATGTTGAATCAGTATTTGATGAATTAC
CGATGATTCTTACTGTTGTAAGCATTCCGAAAATTGAGGATTTGCAATAT
AATAAACGTGGTTGTACTTGGAGTGCTGCTGCAGATAGTCGAGTTAATTT
TACAATTCCTCAAGGAGCTGTCAAAGTTAATTTATCGATGAAAATTACAA
CTGTAGCGTTTGATTCAAGCCTGGTCCAAGAAATAAAGACCAAATCAAAA
GGAACGAATGCGGACAATATTTTCTCTTTTAGTCCATTGTTAAAAATAGA
AGGTGAAAATAGAAGATTTTTGAAACCAGTGTCAATTTCGTTGCCACTTC
CACAAAAACAAATCTCTAAAAATGATTCAAATATACCATTAACAGTATTT
GGATCAAATACAGATTCACGATCAAAGGCTAATTGTGATCCTTCAGGTAT
TGAAGAAAAGATATATCTCTTGACTCAAGATTCTAATAAGAAATGGGTGG
AAAATTCTCAAACTGTTGTGGAATTTGACGAGAAAAAAGATTCTATTAAA
TTGGAAATTGAAAAAGCATCAAATTGGATATTCATGGGCGTACGTGCCAA
AGTTGATGCATCACCAGAGCAAATAGCTAAAGGAATGGAAACTATAATGA
ACCATTTCAAATTGAGACAAATTAAAGTTATAGTATCCCATCATAATGAA
GATCCAAATGTGATATCTGTATCTCTCTGCTCATCAAGTAGGTTAGATAA
ACAGTTGCGGTCACTGAAAGAAGAGGGATTTGATGACAAGAACTGCCAGA
TTAGCCAAGAATTGGAAATTAAGGAACGAGAAATATTAACAGTTCGATTT
AGAGGAAACATAAAATTGAAAAAAGAGAATGAATGTCAGGTCGAAGAATT
CATGTATTCTACCCAATTGAAAAACAAAATTAAAATTCCACTCGAGGTTG
TGGATAAATATGCTCAAAGAGCGAAATCAAAATACGAAGGTTTTCTTTCT
CTGACAACAAGTAAATGGACAAAGAAACCTCAACCAAGGGTTGAAGGTCA
ACCAAGAAAGAATCCACCGCAAATGATAGACGTCGAGGAAATAATTCCAA
TTTATGAAGCAATGTTAGAAATTCCTAAAATTCAGAACTCGAGTACCAGC
AAAGTTTCAAGTCGTGAATTTCATTTTATGAGCAAAGATTACGTGACGCA
AAAATTAATCAAGGAATTATCACTGAAAATCAAAGAAGATTGGAAATGTT
TAGCGAAAGCGCTGGATTTGCCGGCCAATCGAATTGAAGAAATAAAGACT
TTAAACACCAATAAAAAAAACAGCTCAGAAATGGCATATGAAGTTCTAAA
ACTGTGGATCATGCATCTGCCAGTATCTAAAAATAAAGATAAAATCCTGA
AAAAAGCATTGGACAGTATTCATCGCCCGGATTTGATGGAGGACATCAGT
ATTTGAATTATTAATAATTTAGAAATCATAAATTTG
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protein sequence of SMED30032215-orf-1

>SMED30032215-orf-1 ID=SMED30032215-orf-1|Name=SMED30032215-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=824bp
MDKLKQSKLKLKEEINRYLSIETIDKFLGISKDSEKELEDVKIVLQEYIS
EISSDETSLTELTVLIHELTILVSKKFQQFNNENSRSIAEGSSINSDFME
KLELDKAQLKLKYLENSVSFQRMLETLNVVNDKIIEIEKCFAEVTIQEKL
CQEKLIEKERLIEEQKKQKEHNEEIRKEEEQKVIQRANEAALEAKLRQQE
IDKMKKIIEEENKSPEENIEHFIKFRYDLANSEFGEQGIGCFIKALPGFM
VSESDIAVELINPIKINYSFDGTEEIVSNIIHIKTTLSENEDLKFDQPFS
VILPHTMSRTQARETKIFRYFEDELRWTAVDTQDVTIEDNDTSGARYVES
VFDELPMILTVVSIPKIEDLQYNKRGCTWSAAADSRVNFTIPQGAVKVNL
SMKITTVAFDSSLVQEIKTKSKGTNADNIFSFSPLLKIEGENRRFLKPVS
ISLPLPQKQISKNDSNIPLTVFGSNTDSRSKANCDPSGIEEKIYLLTQDS
NKKWVENSQTVVEFDEKKDSIKLEIEKASNWIFMGVRAKVDASPEQIAKG
METIMNHFKLRQIKVIVSHHNEDPNVISVSLCSSSRLDKQLRSLKEEGFD
DKNCQISQELEIKEREILTVRFRGNIKLKKENECQVEEFMYSTQLKNKIK
IPLEVVDKYAQRAKSKYEGFLSLTTSKWTKKPQPRVEGQPRKNPPQMIDV
EEIIPIYEAMLEIPKIQNSSTSKVSSREFHFMSKDYVTQKLIKELSLKIK
EDWKCLAKALDLPANRIEEIKTLNTNKKNSSEMAYEVLKLWIMHLPVSKN
KDKILKKALDSIHRPDLMEDISI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000488Death_domain
IPR011029DEATH-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding