Oxysterol-binding protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032159 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBPL6 (oxysterol binding protein like 6 [Source:HGNC Symbol;Acc:HGNC:16388]) HSP 1 Score: 491.886 bits (1265), Expect = 4.020e-159 Identity = 322/859 (37.49%), Postives = 473/859 (55.06%), Query Frame = 3
Query: 270 GWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKS--NVKIIHPSLSASNPSLHG-VSYGVS-KMLSQP--NPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRKS-QLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + + ++ SPL P N+ G V E D ++ + E KL+Q LEI+ A N D++ + + L +SNP+L + + L+ P + D T+L+ +F A +++LL+S F +A+E + + +++ +K S+ + +L + QN +L++RLNRI +E+ I + S I S D G +S+ S E +S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR+LE G + A +EK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 69 SWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSP-------RDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPL--------PCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQ-NLEILQRTQSAPNFTDMQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANES-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 903
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBPL6 (oxysterol binding protein like 6 [Source:HGNC Symbol;Acc:HGNC:16388]) HSP 1 Score: 485.723 bits (1249), Expect = 1.587e-156 Identity = 322/890 (36.18%), Postives = 474/890 (53.26%), Query Frame = 3
Query: 270 GWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSN-------------------------VKIIHPSLSASNP-SLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRKS-QLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + + ++ SPL P N+ G V E D ++ + E KL+Q LEI+ A N D+++N +++ P + +P LH + + + PP D T+L+ +F A +++LL+S F +A+E + + +++ +K S+ + +L + QN +L++RLNRI +E+ I + S I S D G +S+ S E +S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR+LE G + A +EK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 69 SWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSP-------RDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPL--------PCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQ-NLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANES-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBPL3 (oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370]) HSP 1 Score: 452.21 bits (1162), Expect = 1.254e-144 Identity = 298/799 (37.30%), Postives = 442/799 (55.32%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTL-AEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSN-VKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSR-------NISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM-----KRRTL-----TLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYV--GDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ N P KG L +RKWP+KGW K + ++ GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ ++ E + +F G+ D++ V D+I + I++ + +N S G E + L + E + ++ + E +L+Q ++++ N +++ P L +SNP+L + +G K S + KM + A +Y L+S F ++ E + + L + S+ + L QN DLK RL RI AE+ + L S +V+ S D +AE ++R N S ++ T+ F+DA E L S S+S ++D +SD + ++N+ +R+TL + + K+ RR LPA P S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA+ LERM Y+AAFA+SAYAS++YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG++ NL+ + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YY FTQFA++LN +D + LP TD+RFRPDQR+LE G + EAE +K +IE+LQR
Sbjct: 35 WEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIA--------MFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQ-SMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLL---------------LDSPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEI-VIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR 806
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBPL3 (oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370]) HSP 1 Score: 433.721 bits (1114), Expect = 5.452e-138 Identity = 282/785 (35.92%), Postives = 430/785 (54.78%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTL-AEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSN-VKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQN--NDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTL-----TLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYV--GDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ N P KG L +RKWP+KGW K + ++ GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ ++ E + +F G+ D++ V D+I + I++ + +N S G E + L + E + ++ + E +L+Q ++++ N +++ P L +SNP+L + +G K S + KM + A +Y L+S F ++ E + L SS S V+ L+ +N ++ +A ++++ E+ +S I +S F+ LS S+S++ I++ D +S+++ + + L++ +R+TL + + K+ RR LPA P S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA+ LERM Y+AAFA+SAYAS++YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG++ NL+ + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YY FTQFA++LN +D + LP TD+RFRPDQR+LE G + EAE +K +IE+LQR
Sbjct: 35 WEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAM--------FPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQ-SMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK--LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLS--ITDSLSEFFDAQEVLLSPSSSENEISD-----DDSYVSDISDNLSLDNLSNDLDN----------------------------ERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEI-VIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR 770
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBPL6 (oxysterol binding protein like 6 [Source:HGNC Symbol;Acc:HGNC:16388]) HSP 1 Score: 393.66 bits (1010), Expect = 1.503e-121 Identity = 239/573 (41.71%), Postives = 342/573 (59.69%), Query Frame = 3
Query: 1065 DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRKS-QLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
D T+L+ +F A +++LL+S F +A+E + + +++ +K S+ + +L + QN +L++RLNRI +E+ I + S I S D G +S+ S E +S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR+LE G + A +EK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 374 DYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANES-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 938 HSP 2 Score: 118.242 bits (295), Expect = 2.006e-26 Identity = 53/121 (43.80%), Postives = 78/121 (64.46%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNS 635
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S
Sbjct: 49 WEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRS 169
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-2 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:B2D6P3]) HSP 1 Score: 187.578 bits (475), Expect = 1.282e-51 Identity = 130/389 (33.42%), Postives = 192/389 (49.36%), Query Frame = 3
Query: 1542 PQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQ--KFEVTGTISCPDSRKSQLFGKWTEGIYVGDN-----------------------------ARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVNWKPLWF 2615
P+I+N KR+T+ G+R +LPA S+ +++ N+G+D S+ +PV +NEPLS LQ L E ++Y+ LL+ AAK SD +ER+ Y+AAFA++ ++ R +KPFNP++ ET+E R G +F+AEQVSHHPP+S Y ES+ +++ FW + A P L++ KK ET W+ IYN+ Y+ M S+ A +F + H+ V G I ++ L+G WT + DN ++ +W IPK D + FT F + LN + ++ T+ TDSR R D + LE G EAE K K EE QR GDV P+WF
Sbjct: 4 PKIQNF-KRQTVL----HKGQRTRLPATYIAPEDVSIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEYVAAFALATVSANHKRL-SKPFNPLLLETFELER--NGVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTYDAVFSFDNKGYYNHKGGDVHVEGHIFEGKNKIKALYGNWTLFLASCDNEDFKHHRKEYLRMFNETVSEKDQGPVVPGSKILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDTVAPTDSRRRKDMKALEDGKNDEAEEFKHKYEEEQRERRTTKTGDV---PMWF 381
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-2 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:B2D6P3]) HSP 1 Score: 187.578 bits (475), Expect = 1.552e-51 Identity = 130/389 (33.42%), Postives = 192/389 (49.36%), Query Frame = 3
Query: 1542 PQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQ--KFEVTGTISCPDSRKSQLFGKWTEGIYVGDN-----------------------------ARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVNWKPLWF 2615
P+I+N KR+T+ G+R +LPA S+ +++ N+G+D S+ +PV +NEPLS LQ L E ++Y+ LL+ AAK SD +ER+ Y+AAFA++ ++ R +KPFNP++ ET+E R G +F+AEQVSHHPP+S Y ES+ +++ FW + A P L++ KK ET W+ IYN+ Y+ M S+ A +F + H+ V G I ++ L+G WT + DN ++ +W IPK D + FT F + LN + ++ T+ TDSR R D + LE G EAE K K EE QR GDV P+WF
Sbjct: 14 PKIQNF-KRQTVL----HKGQRTRLPATYIAPEDVSIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEYVAAFALATVSANHKRL-SKPFNPLLLETFELER--NGVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTYDAVFSFDNKGYYNHKGGDVHVEGHIFEGKNKIKALYGNWTLFLASCDNEDFKHHRKEYLRMFNETVSEKDQGPVVPGSKILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDTVAPTDSRRRKDMKALEDGKNDEAEEFKHKYEEEQRERRTTKTGDV---PMWF 391
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 172.555 bits (436), Expect = 3.940e-46 Identity = 128/397 (32.24%), Postives = 212/397 (53.40%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWV--HQKFEVTGTISCPDS-RKSQLFGKWTEGI-------YVGDNARC-----------IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG---------LXXXXXXXXXXXXXLQRIALAKVKGD--VNWKPLWFXXXXXXXXXX--XXFTNEYWSAKKMQ 2687
RR +P +P++ +L +++ IG++LSK+ +PV +EP+SVLQ + E+LEY++LL+ AK S +LE+M Y+AA+A S Y++T +R KPFNP++GET+E+ R D GW+ + EQVSHHPP + + E W+++Q+F + ++F GK + IP G V + K+TT ++NI +I+++GDM T++ + + S+ Q +V G + + K + G W + I + G++ + IW +PK+ +K + FT+ AI+LN + +A TDSR RPDQR +E G L E + + LA KGD ++P WF + + + + ++F YW AK+ Q
Sbjct: 52 RRTTVPE-RPNLP-INLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRT-NKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAP----TDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQ 440
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 174.866 bits (442), Expect = 1.362e-45 Identity = 133/407 (32.68%), Postives = 210/407 (51.60%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRKSQLFGKWTEGI--YV------------------GDNARC-----------IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG---------LXXXXXXXXXXXXXLQRIALAKVKGD--VNWKPLWFXXXXXXXXXX--XXFTNEYWSAKKMQ 2687
RR +P +P++ +L +++ IG++LSK+ +PV +EP+SVLQ + E+LEY++LL+ AK S +LE+M Y+AA+A S Y++T +R KPFNP++GET+E+ R D GW+ + EQVSHHPP + + E W+++Q+F + ++F GK + IP G V + K+TT ++NI +I+++GDM +IT H++N KF S RK + EGI YV G++ + IW +PK+ +K + FT+ AI+LN + +A TDSR RPDQR +E G L E + + LA KGD ++P WF + + + + ++F YW AK+ Q
Sbjct: 230 RRTTVPE-RPNLP-INLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRT-NKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDM----------EITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAP----TDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQ 618
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 174.866 bits (442), Expect = 4.135e-45 Identity = 133/407 (32.68%), Postives = 210/407 (51.60%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRKSQLFGKWTEGI--YV------------------GDNARC-----------IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG---------LXXXXXXXXXXXXXLQRIALAKVKGD--VNWKPLWFXXXXXXXXXX--XXFTNEYWSAKKMQ 2687
RR +P +P++ +L +++ IG++LSK+ +PV +EP+SVLQ + E+LEY++LL+ AK S +LE+M Y+AA+A S Y++T +R KPFNP++GET+E+ R D GW+ + EQVSHHPP + + E W+++Q+F + ++F GK + IP G V + K+TT ++NI +I+++GDM +IT H++N KF S RK + EGI YV G++ + IW +PK+ +K + FT+ AI+LN + +A TDSR RPDQR +E G L E + + LA KGD ++P WF + + + + ++F YW AK+ Q
Sbjct: 335 RRTTVPE-RPNLP-INLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRT-NKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDM----------EITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAP----TDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQ 723
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: Osbp (gene:FBgn0020626 transcript:FBtr0084801) HSP 1 Score: 218.779 bits (556), Expect = 1.439e-59 Identity = 130/340 (38.24%), Postives = 181/340 (53.24%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMN---------------------FTSNLNSSAK-ITFHKSNS--WV-----HQKFEV------TGTISCPDSRKSQLFGKWTEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
RRD++P +P+ SL ++ IG+DLSK+ +P+ NEPLS+LQ L E+ EY+++LD AA D E++ YIAAF VSAYA+T R G KPFNP++GETYE R D GW+ +AEQVSHHPPV+ +CES+NW+ WQEF + +KF GK ++ P G + V W KVTT + NI +++ +G+M F+ ++ S K + +K N WV K E+ +G++S P Y + WR P D DK+Y FT A LN + +A TDSR RPDQR +E G
Sbjct: 386 RRDRVPD-KPN-HPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTG-KPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSP--------------TYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAP----TDSRLRPDQRLMEQG 704
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0072201) HSP 1 Score: 195.282 bits (495), Expect = 8.127e-54 Identity = 107/247 (43.32%), Postives = 148/247 (59.92%), Query Frame = 3
Query: 1605 RDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS-AKITFHKSNSWVHQKFEVTGTISCPDSRKSQ---LFGKWTEGI 2333
R +LPA + S+ +L IG+DLSK+ +PV+LNEPLS LQ LCE +EY+ LL AA+ +RM Y+AAFAVSA AS + R G KPFNP++GETYE + D ++ + EQVSHHPPVS + ES+++ K KFWGKS+E P G++ V K+NE+ W V C++NI +IE YG M T++ A +TF + S V G + D+ ++ L+GKWTE I
Sbjct: 12 RTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLG-KPFNPLLGETYELQKGD--YRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVK--DASETNLYFLYGKWTEFI 253 HSP 2 Score: 50.0618 bits (118), Expect = 8.786e-6 Identity = 37/90 (41.11%), Postives = 50/90 (55.56%), Query Frame = 3
Query: 2358 IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAA--TLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKG--DVNWKPLWF 2615
+W P + +YY FT FA+ LN +DS++ TL TDSR RPD +LE G + A EKT++EE QR + K +W P WF
Sbjct: 335 LWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWF 424
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0343288) HSP 1 Score: 194.897 bits (494), Expect = 9.743e-54 Identity = 107/247 (43.32%), Postives = 148/247 (59.92%), Query Frame = 3
Query: 1605 RDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS-AKITFHKSNSWVHQKFEVTGTISCPDSRKSQ---LFGKWTEGI 2333
R +LPA + S+ +L IG+DLSK+ +PV+LNEPLS LQ LCE +EY+ LL AA+ +RM Y+AAFAVSA AS + R G KPFNP++GETYE + D ++ + EQVSHHPPVS + ES+++ K KFWGKS+E P G++ V K+NE+ W V C++NI +IE YG M T++ A +TF + S V G + D+ ++ L+GKWTE I
Sbjct: 12 RTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLG-KPFNPLLGETYELQKGD--YRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVK--DASETNLYFLYGKWTEFI 253 HSP 2 Score: 50.0618 bits (118), Expect = 8.514e-6 Identity = 37/90 (41.11%), Postives = 50/90 (55.56%), Query Frame = 3
Query: 2358 IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAA--TLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKG--DVNWKPLWF 2615
+W P + +YY FT FA+ LN +DS++ TL TDSR RPD +LE G + A EKT++EE QR + K +W P WF
Sbjct: 337 LWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWF 426
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG42668 (gene:FBgn0261550 transcript:FBtr0302666) HSP 1 Score: 88.9669 bits (219), Expect = 7.643e-18 Identity = 61/158 (38.61%), Postives = 85/158 (53.80%), Query Frame = 3
Query: 1647 SLINLLCKNI--GRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFY---RAGTKPFNPIIGETYE-YVRPDKGWK--FIAEQVSHHPPVSVCYC--ESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYL 2090
SLI + K + G DLSKV LP + EP S L L + ++DLL A + D+ RM + V Y S+FY + KP+NPI+GE + Y + G + +IAEQVSHHPPVS Y + +SI K+KF+G S A+ G+ + L
Sbjct: 104 SLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLV----VQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTL 257
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG42668 (gene:FBgn0261550 transcript:FBtr0306634) HSP 1 Score: 88.5817 bits (218), Expect = 1.405e-17 Identity = 61/158 (38.61%), Postives = 85/158 (53.80%), Query Frame = 3
Query: 1647 SLINLLCKNI--GRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFY---RAGTKPFNPIIGETYE-YVRPDKGWK--FIAEQVSHHPPVSVCYC--ESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYL 2090
SLI + K + G DLSKV LP + EP S L L + ++DLL A + D+ RM + V Y S+FY + KP+NPI+GE + Y + G + +IAEQVSHHPPVS Y + +SI K+KF+G S A+ G+ + L
Sbjct: 296 SLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLV----VQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTL 449
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 472.626 bits (1215), Expect = 7.209e-152 Identity = 301/818 (36.80%), Postives = 441/818 (53.91%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPEL------VRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSK--MLSQPNP--PDMTQLKM------------------IQFTES--ASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL----------------TLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
Q+ WEIIEG+ + RP+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRL+RQ +++ S +D + FP + A SP + K +S ++ P V E D ++ + E +L+Q LEI+ A N D++SN + S S + VSK L Q P M+Q+++ + T+ ++G Y LQ F +A + ++L + +T E K VLL +L + QN +LK RLNRI +E+ +S + S+ + + + L V +++ V N ++S + F+DA E L S S+S ++D +SD + +N M L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEY++LLD AA++ D ERM +AAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG+ F +EQVSHHPP+S C+C+S+N++ WQ+ R KNKFWGKS+E +P G++ V L + + WNKVTTC++NI R+IEHYG++ T + K++F K N W EV G++ + R +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FA++LN L ++ LP TD+RFRPDQR+LE G
Sbjct: 49 QEPDSWEIIEGLRIGQTHVQRPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSPDVFDLWVCKLRHHRLFRQNEIVRSP-------RDATLRTFP------------PSAGAESPQNTPSSTHPKKGKPSSFPWQLPPSCSNGQSKVAAWLQESEEMDKCAEELAYCQSSLLELNQLLQ-SLEILQRTQSAPNFTDMQSNC--VDLSKKEKRVSRRWRTKSVSKDAKLQQQVPLSASMSQVRLHSSNPNLCAELADFQAPVTRLTDGIDSAGDYIKLQEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLLDHEQTGQSNQIVTLRRSLSQALSQNAELKTRLNRIHSESVLSEQVVSVNIISSPDEACEPLHVGLP---LSQQVSNESRLSMSESVSE--FFDAQEVLLSASSSENEASDDESYVSDVSDNISEDNASVTDNVSRQMPNGELASSMFRNGRRPCLPAPAPDTSNINLWNILKNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAQTDDPYERMAIVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCDSQNFTFWQDVRWKNKFWGKSMEILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTRSTTCICKLSFIKGNYWSSNVNEVQGSVMDQEGRVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAVELNELFPEMKELLPPTDARFRPDQRFLEEG 839
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 457.988 bits (1177), Expect = 2.294e-146 Identity = 297/812 (36.58%), Postives = 437/812 (53.82%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSK--MLSQPNP--PDMTQLKM------------------IQFTES--ASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL----------------TLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
Q+ WEIIEG+ + RP+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRL+RQ +++ S +D + FP + E Q+ ++ P + P + S + G V E D ++ + E +L+Q LEI+ A N D++SN + S S + VSK L Q P M+Q+++ + T+ ++G Y LQ F +A + ++L + +T E K VLL +L + QN +LK RLNRI +E+ +S + S+ + + + L V +++ V N ++S + F+DA E L S S+S ++D +SD + +N M L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEY++LLD AA++ D ERM +AAFAVS Y+ST+YRAG+KPFNP++GETYE +R DK VSHHPP+S C+C+S+N++ WQ+ R KNKFWGKS+E +P G++ V L + + WNKVTTC++NI R+IEHYG++ T + K++F K N W EV G++ + R +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FA++LN L ++ LP TD+RFRPDQR+LE G
Sbjct: 49 QEPDSWEIIEGLRIGQTHVQRPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSPDVFDLWVCKLRHHRLFRQNEIVRSP-------RDATLRTFPPSA---GAESPQNTPSSTHPKKQGKPSSFPWQLPPSCSN--GQSKVAAWLQESEEMDKCAEELAYCQSSLLELNQLLQ-SLEILQRTQSAPNFTDMQSNC--VDLSKKEKRVSRRWRTKSVSKDAKLQQQVPLSASMSQVRLHSSNPNLCAELADFQAPVTRLTDGIDSAGDYIKLQEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLLDHEQTGQSNQIVTLRRSLSQALSQNAELKTRLNRIHSESVLSEQVVSVNIISSPDEACEPLHVGLP---LSQQVSNESRLSMSESVSE--FFDAQEVLLSASSSENEASDDESYVSDVSDNISEDNASVTDNVSRQMPNGELASSMFRNGRRPCLPAPAPDTSNINLWNILKNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAQTDDPYERMAIVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDK--------VSHHPPISACHCDSQNFTFWQDVRWKNKFWGKSMEILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTRSTTCICKLSFIKGNYWSSNVNEVQGSVMDQEGRVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAVELNELFPEMKELLPPTDARFRPDQRFLEEG 832
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbpl3b (oxysterol binding protein-like 3b [Source:ZFIN;Acc:ZDB-GENE-090109-1]) HSP 1 Score: 377.096 bits (967), Expect = 1.389e-116 Identity = 249/601 (41.43%), Postives = 345/601 (57.40%), Query Frame = 3
Query: 990 LSASNPSLHGVSYGVSKMLSQP--NPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-----TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM------KRRTLTL----YQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS---SAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNEYWSAKK-MQFKNVQFPILW 2717
L ASNP+L V K +P +P D+++L+ F A+ ++ ++S L E + V + E S + L L QN +L+ RL +I AE+ IS P++ GPL+ S + N +IS + F+DA E L S S+S +ED ISD + ++N + T L +QE+ RR LP+ P+ S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA + D ERM YIA FAVS YAS++YRAG KPFNP++GETYE RPDKG++F+AEQVSHHPP+S C+ ES+N+ WQ+ R +NKFWGKS+E +P GS V L F + WNKVT+CI+NI R+IEHYG+++ N NS K+TF K+ W EV G+++ + +LFGKW EG+Y G +A CIWR +P + ++YYGFT+FA++LN LD LP TD+R RPDQR LE G + AE +K +IE+LQR ++ + + +P +F+K + S N YW +K F N+ P+LW
Sbjct: 244 LHASNPNLSSVDLTTEKTYHEPLDSPIDVSKLQE-DFCRVANNLHTTMKSALCMLTTEKERV----KQMLEHEPCPSPSAQLLGLKNALTAAVTQNAELRERLCKIHAESHISE--PTVHINLSPGPLQKQDSSDCSRPLVHQASNESRASISESLSE--FFDAQEVLLSASSSENEASEDDSYISDISDNVSMDNFSNEAENERLNTGCLVNGGFQEQ--RRSCLPSPSPNTSNISLWNILKNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAHTQDPFERMVYIATFAVSGYASSYYRAGGKPFNPVLGETYECDRPDKGFRFVAEQVSHHPPISSCHAESKNFIFWQDVRWRNKFWGKSMEIVPVGSSHVVLPGFGDHYEWNKVTSCIHNILSGQRWIEHYGEISI-KNSNSEKCQCKVTFIKAKYWNSSMNEVEGSVTDHKGKVVHKLFGKWHEGMYCGSPPSATCIWRTNPMPPEFEQYYGFTKFAMELNELDPLTKPLLPPTDTRLRPDQRLLEEGNVQSAEVQKQRIEQLQRERRKVLEENHMTHQPRFFQKSKDETWVS---NNTYWDLRKDPGFSNLDCPVLW 829 HSP 2 Score: 62.003 bits (149), Expect = 2.715e-9 Identity = 26/51 (50.98%), Postives = 36/51 (70.59%), Query Frame = 3
Query: 465 IDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
ID+GL+V+ K K + ID+D++ YHLK+K + FD WV +R HRLYRQ
Sbjct: 46 IDVGLSVMAIKKKAKCIDLDTEENIYHLKIKSQELFDEWVSKLRHHRLYRQ 96
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbpl3b (oxysterol binding protein-like 3b [Source:ZFIN;Acc:ZDB-GENE-090109-1]) HSP 1 Score: 377.096 bits (967), Expect = 4.788e-116 Identity = 249/601 (41.43%), Postives = 345/601 (57.40%), Query Frame = 3
Query: 990 LSASNPSLHGVSYGVSKMLSQP--NPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-----TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM------KRRTLTL----YQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS---SAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNEYWSAKK-MQFKNVQFPILW 2717
L ASNP+L V K +P +P D+++L+ F A+ ++ ++S L E + V + E S + L L QN +L+ RL +I AE+ IS P++ GPL+ S + N +IS + F+DA E L S S+S +ED ISD + ++N + T L +QE+ RR LP+ P+ S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA + D ERM YIA FAVS YAS++YRAG KPFNP++GETYE RPDKG++F+AEQVSHHPP+S C+ ES+N+ WQ+ R +NKFWGKS+E +P GS V L F + WNKVT+CI+NI R+IEHYG+++ N NS K+TF K+ W EV G+++ + +LFGKW EG+Y G +A CIWR +P + ++YYGFT+FA++LN LD LP TD+R RPDQR LE G + AE +K +IE+LQR ++ + + +P +F+K + S N YW +K F N+ P+LW
Sbjct: 297 LHASNPNLSSVDLTTEKTYHEPLDSPIDVSKLQE-DFCRVANNLHTTMKSALCMLTTEKERV----KQMLEHEPCPSPSAQLLGLKNALTAAVTQNAELRERLCKIHAESHISE--PTVHINLSPGPLQKQDSSDCSRPLVHQASNESRASISESLSE--FFDAQEVLLSASSSENEASEDDSYISDISDNVSMDNFSNEAENERLNTGCLVNGGFQEQ--RRSCLPSPSPNTSNISLWNILKNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAHTQDPFERMVYIATFAVSGYASSYYRAGGKPFNPVLGETYECDRPDKGFRFVAEQVSHHPPISSCHAESKNFIFWQDVRWRNKFWGKSMEIVPVGSSHVVLPGFGDHYEWNKVTSCIHNILSGQRWIEHYGEISI-KNSNSEKCQCKVTFIKAKYWNSSMNEVEGSVTDHKGKVVHKLFGKWHEGMYCGSPPSATCIWRTNPMPPEFEQYYGFTKFAMELNELDPLTKPLLPPTDTRLRPDQRLLEEGNVQSAEVQKQRIEQLQRERRKVLEENHMTHQPRFFQKSKDETWVS---NNTYWDLRKDPGFSNLDCPVLW 882 HSP 2 Score: 110.153 bits (274), Expect = 3.970e-24 Identity = 48/115 (41.74%), Postives = 70/115 (60.87%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
WEI+EG+ + + P+ G + +RKWPMKGW K Y ++ GI+ Y+K + K ID+GL+V+ K K + ID+D++ YHLK+K + FD WV +R HRLYRQ
Sbjct: 35 WEIVEGLRGGHSNVQEPEKQAGFMLKKRKWPMKGWHKRYFYLDKGILKYAKCAADVEKGKLHGCIDVGLSVMAIKKKAKCIDLDTEENIYHLKIKSQELFDEWVSKLRHHRLYRQ 149
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbpl3b (oxysterol binding protein-like 3b [Source:ZFIN;Acc:ZDB-GENE-090109-1]) HSP 1 Score: 358.992 bits (920), Expect = 4.506e-110 Identity = 193/386 (50.00%), Postives = 257/386 (66.58%), Query Frame = 3
Query: 1584 YQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS---SAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNEYWSAKK-MQFKNVQFPILW 2717
+QE+ RR LP+ P+ S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA + D ERM YIA FAVS YAS++YRAG KPFNP++GETYE RPDKG++F+AEQVSHHPP+S C+ ES+N+ WQ+ R +NKFWGKS+E +P GS V L F + WNKVT+CI+NI R+IEHYG+++ N NS K+TF K+ W EV G+++ + +LFGKW EG+Y G +A CIWR +P + ++YYGFT+FA++LN LD LP TD+R RPDQR LE G + AE +K +IE+LQR ++ + + +P +F+K + S N YW +K F N+ P+LW
Sbjct: 414 FQEQ--RRSCLPSPSPNTSNISLWNILKNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAHTQDPFERMVYIATFAVSGYASSYYRAGGKPFNPVLGETYECDRPDKGFRFVAEQVSHHPPISSCHAESKNFIFWQDVRWRNKFWGKSMEIVPVGSSHVVLPGFGDHYEWNKVTSCIHNILSGQRWIEHYGEISI-KNSNSEKCQCKVTFIKAKYWNSSMNEVEGSVTDHKGKVVHKLFGKWHEGMYCGSPPSATCIWRTNPMPPEFEQYYGFTKFAMELNELDPLTKPLLPPTDTRLRPDQRLLEEGNVQSAEVQKQRIEQLQRERRKVLEENHMTHQPRFFQKSKDETWVS---NNTYWDLRKDPGFSNLDCPVLW 793 HSP 2 Score: 62.003 bits (149), Expect = 2.949e-9 Identity = 26/51 (50.98%), Postives = 36/51 (70.59%), Query Frame = 3
Query: 465 IDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
ID+GL+V+ K K + ID+D++ YHLK+K + FD WV +R HRLYRQ
Sbjct: 46 IDVGLSVMAIKKKAKCIDLDTEENIYHLKIKSQELFDEWVSKLRHHRLYRQ 96
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBPL6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:734134]) HSP 1 Score: 503.442 bits (1295), Expect = 4.492e-164 Identity = 335/870 (38.51%), Postives = 481/870 (55.29%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK--SNVKIIHPSLSASNPSLHG-VSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
Q++ WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D++ + + L ASNP+L+ V + NPP D T+L+ +F A +++LL+S + +A+E + + + + +S+ + +L + N++L++RLNRI E+ IS + S I S+D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + +F+K + +N+ YW +K F V P+LW
Sbjct: 34 QEADSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPEGKVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLH-NLELLQRTQSAPNFIDMQVPHSASMSPVRLHASNPNLYADVEFQ--------NPPSHVVDAMEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASSDESCEPMHVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTTKYFRKVIDFHQKEMWISNDTYWELRKDPGFSKVDLPVLW 871
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBPL6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:734134]) HSP 1 Score: 498.434 bits (1282), Expect = 1.675e-162 Identity = 332/861 (38.56%), Postives = 478/861 (55.52%), Query Frame = 3
Query: 264 SFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQV-----QDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK--SNVKIIHPSLSASNPSLHG-VSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
S WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP +++ Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D++ + + L ASNP+L+ V + NPP D T+L+ +F A +++LL+S + +A+E + + + + +S+ + +L + N++L++RLNRI E+ IS + S+ + + P+ +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + +F+K + +N+ YW +K F V P+LW
Sbjct: 19 SDSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLH-NLELLQRTQSAPNFIDMQVPHSASMSPVRLHASNPNLYADVEFQ--------NPPSHVVDAMEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASSDEPMH-VSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTTKYFRKVIDFHQKEMWISNDTYWELRKDPGFSKVDLPVLW 846
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBPL6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:734134]) HSP 1 Score: 485.337 bits (1248), Expect = 2.270e-156 Identity = 314/829 (37.88%), Postives = 449/829 (54.16%), Query Frame = 3
Query: 255 HQKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKII-------------------------------HPSLS-----ASNPSLHG-VSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQR 2498
H+++ WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D+++N I H S+S ASNP+L+ V + NPP D T+L+ +F A +++LL+S + +A+E + + + + +S+ + +L + N++L++RLNRI E+ IS + S I S+D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR
Sbjct: 64 HKEADSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPEGKVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLH-NLELLQRTQSAPNFIDMQANCVDISKKDKRASRRWRTKSVSKDAKIQLQCRAMEKHASMSPVRLHASNPNLYADVEFQ--------NPPSHVVDAMEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASSDESCEPMHVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQR 860
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBPL6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:734134]) HSP 1 Score: 478.019 bits (1229), Expect = 1.328e-154 Identity = 327/862 (37.94%), Postives = 466/862 (54.06%), Query Frame = 3
Query: 351 RRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETND----DIPSSVSTGFVL--INEDLKLIQEK------LEIMAENMD-------------------DIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
+RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P N+ G V L E D D+ S L + +L+L+Q +++ A +D D K +++ H S S S LH + + + NPP D T+L+ +F A +++LL+S + +A+E + + + + +S+ + +L + N++L++RLNRI E+ IS + S I S+D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + +F+K + +N+ YW +K F V P+LW
Sbjct: 4 KRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPEGKVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLHNLELLQRTQSAPNFIDMQANCVDISKKDKRASRRWRTKSVSKDAKIQLQVPH-SASMSPVRLHASNPNLYADVEFQNPPSHVVDAMEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASSDESCEPMHVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTTKYFRKVIDFHQKEMWISNDTYWELRKDPGFSKVDLPVLW 841
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBPL6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:734134]) HSP 1 Score: 476.478 bits (1225), Expect = 2.116e-154 Identity = 323/837 (38.59%), Postives = 459/837 (54.84%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQV-----QDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK--SNVKIIHPSLSASNPSLHG-VSYGVSKMLSQPNPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFY-DAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP +++ Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D++ + + L ASNP+L+ V + NPP ++ E AS Y LQ F +A + ++L + +T E K +++ ++ + Q+ + ARL R + S+P G L S+S S S+ + A+ V+ S + + + E + D ++ + D+ S QI N L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + +F+K + +N+ YW +K F V P+LW
Sbjct: 22 WEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLH-NLELLQRTQSAPNFIDMQVPHSASMSPVRLHASNPNLYADVEFQ--------NPPS----HVVDAMEFASD-YTKLQEEFCLIAQKVHSLLKSAYNTIAIEKEKMKQ-MVSDQDYSGQSTQI-ARL-RQSLSQPMHVSLPLSQQVSNEGRL-SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSR-----------QILN----GELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTTKYFRKVIDFHQKEMWISNDTYWELRKDPGFSKVDLPVLW 810
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl6 (oxysterol binding protein-like 6 [Source:MGI Symbol;Acc:MGI:2139014]) HSP 1 Score: 484.567 bits (1246), Expect = 3.460e-156 Identity = 320/881 (36.32%), Postives = 475/881 (53.92%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPG----------NIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK-------------------SNVKIIHPSLSASNP-SLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + + ++ SPL P N+ G V E D ++ + E KL+Q LEI+ A N D++ + V P + +P LH + + + PP D T+L+ +F A +++LL+S F +A+E + + +++ K S+ + +L + QN +L++RLNRI +E++I + S+ + + P + VS +++ V N ++S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FA++LN LD L LP TD+RFRPDQR+LE G + A AEK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 70 WEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSP-------RDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPL--------PCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQ-NLEILQRTQSAPNFTDMQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLP---LSQQVANESRLSMSE--SVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 928
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl3 (oxysterol binding protein-like 3 [Source:MGI Symbol;Acc:MGI:1918970]) HSP 1 Score: 456.833 bits (1174), Expect = 1.465e-146 Identity = 296/793 (37.33%), Postives = 446/793 (56.24%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMV---DKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSN-VKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGV--INRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM-----KRRTLTLYQEKTG-----RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ P KG L +RKWP+KGW K + +E GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ ++ + + +F G+ D+ V +++ + +++ + P +N S D P +++ E+ + D+ + ++L ++ + E ++++ N +++ P L +SNP+L + +G K S + KM + A +Y L+S F +++E + + L T+ S+ + L QN DLK RL RI AE S+ P++ P +L+ S D V ++ +SR +S + F+DA E L S S+S ++D +SD + ++N+ +R+TL E +G RR LPA P+ S SL ++L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD A++ LERM Y+AAFA+SAYAS+++RAG+KPFNP++GETYE +R DKG++F AEQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG+++ NLN + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YYGFTQFA++LN +D + LP TD+RFRPDQR LE G I EAE +K +IE+LQR
Sbjct: 34 WEVVEGLRGEMTYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEELFDEWVSKLRHHRMYRQNEIAM--------FPRDVNHFFSGSSVTDSAPGVFESVSSRKRSSLSKQNSFPPGSNLSFSCGGDTRVPFWLQSSEDMEKCSKDM--AHCHAYLL---EMSQLLESMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISVEREKLKQLMELDTSPSPSAQVVGLKHALSSALAQNTDLKERLRRIHAE-SLLLDPPAVPK-----PGDNLAEENSRDEGRALVHQLSNESR-LSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLESSGEARSKRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIK-NLNDDSCHCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQR 805
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl6 (oxysterol binding protein-like 6 [Source:MGI Symbol;Acc:MGI:2139014]) HSP 1 Score: 437.573 bits (1124), Expect = 8.334e-140 Identity = 293/789 (37.14%), Postives = 433/789 (54.88%), Query Frame = 3
Query: 405 GIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPG----------NIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSN-------------------------VKIIHPSLSASNP-SLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTL----TLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
G++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + + ++ SPL P N+ G V E D ++ + E KL+Q LEI+ A N D+++N +++ P + +P LH + + + PP D T+L+ +F A +++LL+S F +A+E + + +++ K S+ + +L + QN +L++RLNRI +E++I + S+ + + P + VS +++ V N ++S + F+DA E L S S+S ++D ISD + +N + R+ L T + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FA++LN LD L LP TD+RFRPDQR+LE G + A AEK ++EELQR
Sbjct: 1 GMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSP-------RDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPL--------PCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQ-NLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLP---LSQQVANESRLSMSE--SVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQR 767
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl3 (oxysterol binding protein-like 3 [Source:MGI Symbol;Acc:MGI:1918970]) HSP 1 Score: 436.032 bits (1120), Expect = 5.850e-139 Identity = 279/787 (35.45%), Postives = 434/787 (55.15%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMV---DKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSN-VKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQN--NDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTG-----RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ P KG L +RKWP+KGW K + +E GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ ++ + + +F G+ D+ V +++ + +++ + P +N S D P +++ E+ + D+ + ++L ++ + E ++++ N +++ P L +SNP+L + +G K S + KM + A +Y L+S F +++E + + T S S V+ L+ +N ++ +A ++++ E+ +S I +S F+ LS S+S++ I++ D +S+++ + + L++ +R+TL E +G RR LPA P+ S SL ++L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD A++ LERM Y+AAFA+SAYAS+++RAG+KPFNP++GETYE +R DKG++F AEQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG+++ NLN + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YYGFTQFA++LN +D + LP TD+RFRPDQR LE G I EAE +K +IE+LQR
Sbjct: 34 WEVVEGLRGEMTYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEELFDEWVSKLRHHRMYRQNEIAM--------FPRDVNHFFSGSSVTDSAPGVFESVSSRKRSSLSKQNSFPPGSNLSFSCGGDTRVPFWLQSSEDMEKCSKDM--AHCHAYLL---EMSQLLESMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISVEREKLKQLMELDTS--PSPSAQVVGLKHALSSENSRDEGRALVHQLSNESRLS--ITDSLSEFFDAQEVLLSPSSSENEISD-----DDSYVSDISDNLSLDNLSNDLDN----------------------------ERQTLGPVLESSGEARSKRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIK-NLNDDSCHCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQR 769
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl7 (oxysterol binding protein-like 7 [Source:MGI Symbol;Acc:MGI:1918490]) HSP 1 Score: 429.483 bits (1103), Expect = 2.960e-136 Identity = 301/808 (37.25%), Postives = 430/808 (53.22%), Query Frame = 3
Query: 258 QKSFGWEIIE---GVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDIN----EDDEGPKKNNTSMVDKIGP--ELVRTMTLAEETNDDIPSS--VSTGFVLINEDLKLIQEKLEIM----AENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPN---PPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRD-------SRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTG---------RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
Q S WE++E G + +++I+ P+ +G L +RKWP+KGW K Y +E+GI+ Y+ + K ID+ L+V++ K QRID+D+++ YHLK+K D F WV +R+HR L+ +M + PG L A+ P + D +G + + ++ + G EL R + E + IPS+ + T + + ++ M DD V +H S+ P+L Y S+ S P PPD L+ F A ++N L S L E D + + S LS+ V+ + D + RL+ S SI S + D S S ++ A + R+ S +S + F+DA E L S S+S +E+ + + E ++ R YQ+ RR LPA + SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS LLD A++ +D ERM YIAAFAVSAY+ST++RAG KPFNP++GETYE RPD+G++FI+EQVSHHPP+S C+ ESEN+ WQ+ + KNKFWGKS+E +P G++ V L +F + WNKVT+CI+NI R+IEHYG++ + +SS KITF K+ W EV G + R +LFGKW EG+Y G +CIW+P ++P DH++ +GFTQFA++LN L S+L TLP TD+R RPDQRYLE G I AEA+K +IE+LQR
Sbjct: 25 QASELWEVMEEPRGRL-GADDIM-PERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFHSWVAQLRAHR-----------LAQRLDMPSATHRKAPGTQMLTAGSA--SALPGVGPREKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHR-IPSAPVIPTHQTSVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSV----PNL--SRYLESRDTSGPRGLPPPDYAHLQR-SFWALAQKVHNSLSSVLVALTTERDRL-----RDLHQGSELSRMVV-------SEAPDGQRRLH--------SLSISSDTTAD------SFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDIRGADRYQKGPCVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQR 783
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q9BZF3|OSBL6_HUMAN (Oxysterol-binding protein-related protein 6 OS=Homo sapiens OX=9606 GN=OSBPL6 PE=1 SV=1) HSP 1 Score: 485.723 bits (1249), Expect = 7.619e-156 Identity = 322/890 (36.18%), Postives = 474/890 (53.26%), Query Frame = 3
Query: 270 GWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSN-------------------------VKIIHPSLSASNP-SLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRKS-QLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + + ++ SPL P N+ G V E D ++ + E KL+Q LEI+ A N D+++N +++ P + +P LH + + + PP D T+L+ +F A +++LL+S F +A+E + + +++ +K S+ + +L + QN +L++RLNRI +E+ I + S I S D G +S+ S E +S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR+LE G + A +EK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 69 SWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSP-------RDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPL--------PCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQ-NLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANES-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q9DBS9|OSBL3_MOUSE (Oxysterol-binding protein-related protein 3 OS=Mus musculus OX=10090 GN=Osbpl3 PE=1 SV=2) HSP 1 Score: 456.833 bits (1174), Expect = 1.025e-145 Identity = 296/793 (37.33%), Postives = 446/793 (56.24%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMV---DKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSN-VKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGV--INRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM-----KRRTLTLYQEKTG-----RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ P KG L +RKWP+KGW K + +E GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ ++ + + +F G+ D+ V +++ + +++ + P +N S D P +++ E+ + D+ + ++L ++ + E ++++ N +++ P L +SNP+L + +G K S + KM + A +Y L+S F +++E + + L T+ S+ + L QN DLK RL RI AE S+ P++ P +L+ S D V ++ +SR +S + F+DA E L S S+S ++D +SD + ++N+ +R+TL E +G RR LPA P+ S SL ++L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD A++ LERM Y+AAFA+SAYAS+++RAG+KPFNP++GETYE +R DKG++F AEQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG+++ NLN + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YYGFTQFA++LN +D + LP TD+RFRPDQR LE G I EAE +K +IE+LQR
Sbjct: 34 WEVVEGLRGEMTYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEELFDEWVSKLRHHRMYRQNEIAM--------FPRDVNHFFSGSSVTDSAPGVFESVSSRKRSSLSKQNSFPPGSNLSFSCGGDTRVPFWLQSSEDMEKCSKDM--AHCHAYLL---EMSQLLESMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISVEREKLKQLMELDTSPSPSAQVVGLKHALSSALAQNTDLKERLRRIHAE-SLLLDPPAVPK-----PGDNLAEENSRDEGRALVHQLSNESR-LSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLESSGEARSKRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIK-NLNDDSCHCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQR 805
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q8BXR9|OSBL6_MOUSE (Oxysterol-binding protein-related protein 6 OS=Mus musculus OX=10090 GN=Osbpl6 PE=1 SV=1) HSP 1 Score: 394.045 bits (1011), Expect = 9.380e-121 Identity = 237/571 (41.51%), Postives = 346/571 (60.60%), Query Frame = 3
Query: 1065 DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXX---------XXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKV-KGDVNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
D T+L+ +F A +++LL+S F +A+E + + +++ K S+ + +L + QN +L++RLNRI +E++I + S+ + + P + VS +++ V N ++S + F+DA E L S S+S ++D + I + LT + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEE+EYS+LLD A+++ D ERM +AAFAVS Y ST++RAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G+L V L K+ + WNKVTTCI+NI R+IEHYG++ + +S K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P +++ YYGFT+FA++LN LD L LP TD+RFRPDQR+LE G + A AEK ++EELQR + + ++ P +FKK + +N+ YW +K F V P+LW
Sbjct: 395 DYTKLQE-EFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLP---LSQQVANESRLSMSE--SVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 959 HSP 2 Score: 118.242 bits (295), Expect = 1.040e-25 Identity = 53/122 (43.44%), Postives = 78/122 (63.93%), Query Frame = 3
Query: 270 GWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNS 635
WEIIEG+ + +PD +G + +RKWP+KGW K + ++NG++ YSK+ K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S
Sbjct: 69 SWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRS 190
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q9H4L5|OSBL3_HUMAN (Oxysterol-binding protein-related protein 3 OS=Homo sapiens OX=9606 GN=OSBPL3 PE=1 SV=1) HSP 1 Score: 369.777 bits (948), Expect = 2.720e-112 Identity = 235/570 (41.23%), Postives = 332/570 (58.25%), Query Frame = 3
Query: 954 DIKSNVKIIHP-----SLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-FTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSR-------NISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIM-----KRRTL-----TLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYV--GDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
D K +++ P L +SNP+L + +G K S + KM + A +Y L+S F ++ E + + L + S+ + L QN DLK RL RI AE+ + L S +V+ S D +AE ++R N S ++ T+ F+DA E L S S+S ++D +SD + ++N+ +R+TL + + K+ RR LPA P S SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA+ LERM Y+AAFA+SAYAS++YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+ ES N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R+IEHYG++ NL+ + K+ F K+ W E+ GT+ + +LFGKW E IY G ++ C+WR +PK +++YY FTQFA++LN +D + LP TD+RFRPDQR+LE G + EAE +K +IE+LQR
Sbjct: 284 DAKGTLQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLL---------------LDSPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEI-VIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR 837 HSP 2 Score: 106.686 bits (265), Expect = 3.470e-22 Identity = 47/115 (40.87%), Postives = 69/115 (60.00%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
WE++EG+ N P KG L +RKWP+KGW K + ++ GI+ Y+KS + ID+GL+V++ K + ID+D++ YHLKVK + FD WV +R HR+YRQ
Sbjct: 35 WEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQ 149
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q9BZF2|OSBL7_HUMAN (Oxysterol-binding protein-related protein 7 OS=Homo sapiens OX=9606 GN=OSBPL7 PE=1 SV=1) HSP 1 Score: 365.54 bits (937), Expect = 3.117e-111 Identity = 179/326 (54.91%), Postives = 236/326 (72.39%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
RR LPA + SL N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS LLD A++ +D ERM YIAAFAVSAY+ST++RAG KPFNP++GETYE RPD+G++FI+EQVSHHPP+S C+ ESEN++ WQ+ + KNKFWGKS+E +P G++ V L +F + WNKVT+CI+N+ R+IEHYG++ + +SS KITF K+ W EV G + R +LFGKW EG+Y G +CIW+P ++P DH++ +GFTQFA++LN L ++L +LP TD+R RPDQRYLE G I AEA+K +IE+LQR
Sbjct: 463 RRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQR 788 HSP 2 Score: 97.0561 bits (240), Expect = 3.980e-19 Identity = 47/118 (39.83%), Postives = 70/118 (59.32%), Query Frame = 3
Query: 258 QKSFGWEIIE-GVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRL 608
Q S WE++E V E + P+ +G L +RKWP+KGW K Y +E+GI+ Y+ + K ID+ L+V++ K QRID+D+++ YHLK+K D F WV +R+HRL
Sbjct: 25 QASELWEVVEEPRVRLGTEGVMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRL 142
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A1L8EPC2 (Oxysterol-binding protein OS=Xenopus laevis OX=8355 GN=osbpl6 PE=3 SV=1) HSP 1 Score: 509.605 bits (1311), Expect = 7.581e-163 Identity = 335/900 (37.22%), Postives = 497/900 (55.22%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVS---TGFVLINE---DLKLIQEK------LEIMAENMD-------------------DIKSNVKIIHPS------LSASNPSLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLT---LYQE------KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
Q++ WEIIEG+ + + +P+ +G + +RKWP+KGW K + +++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P NN G V L E D ++ +G + +++ +L+L+Q +++ A +D D K ++++ + + L ASNP+L+ NPP D T+L+ +F A +++LL+S + +A+E + + +++ + + + +S+ + +L + N++LK+RLNRI E+ IS + S I S D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N ++ LY E +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S+ K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP+TD+RFRPDQR LE G + A EK + EELQR ++ D + + P +F+K + + +N+ YW +K F V P+LW
Sbjct: 34 QETDSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFALDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSQDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVSVPEGKVPQNNFLWQSPI--------PSSNNLPATWTTGQNKVAAWLLDSEEMDKCAEDLAKCQSGLIELSKLLHNLELLQRTQSAPNFIDMQANCVDISKKDKRASRRWRTKSVSKDAKIHLQVPYSASMSPVRLHASNPNLYADE-------EFQNPPSHVVDALELASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSSQNTQISR-LRQSLSQALNHNSELKSRLNRIHTESVISDQVVSVNIIASPDESCEQMQVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILYGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYSSTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYVWNKVTTCIHNILSGRRWIEHYGEITIRNTKNYISTCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPRTDARFRPDQRLLEEGNVEAAAMEKQRTEELQRSRRKCMEEDHIEYTPKYFRKVIDNHQKEMWISNDTYWELRKDPGFSKVNLPVLW 902
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A5G3L2U0 (Oxysterol-binding protein OS=Xenopus tropicalis OX=8364 GN=osbpl6 PE=3 SV=1) HSP 1 Score: 503.442 bits (1295), Expect = 7.053e-161 Identity = 335/870 (38.51%), Postives = 481/870 (55.29%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK--SNVKIIHPSLSASNPSLHG-VSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV-LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
Q++ WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D++ + + L ASNP+L+ V + NPP D T+L+ +F A +++LL+S + +A+E + + + + +S+ + +L + N++L++RLNRI E+ IS + S I S+D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM IAAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ T N S K+TF K + W EV G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGFT+FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + +F+K + +N+ YW +K F V P+LW
Sbjct: 34 QEADSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSPDTFDAWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPEGKVPQNNFLWQSPI--------PCSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSNLIELSKLLH-NLELLQRTQSAPNFIDMQVPHSASMSPVRLHASNPNLYADVEFQ--------NPPSHVVDAMEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQSTQIARLRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASSDESCEPMHVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALIAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVTLPKYGDCYIWNKVTTCIHNILSGRRWIEHYGEITIRNTKNCVSMCKMTFIKGSYWNSSANEVHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDFLPLTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTTKYFRKVIDFHQKEMWISNDTYWELRKDPGFSKVDLPVLW 871
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A1L8EWE6 (Oxysterol-binding protein OS=Xenopus laevis OX=8355 GN=osbpl6 PE=3 SV=1) HSP 1 Score: 502.671 bits (1293), Expect = 1.254e-160 Identity = 329/870 (37.82%), Postives = 486/870 (55.86%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFP----------GNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK--SNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPP-----------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPS---IVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI-----MKRRTLTLY----QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGD-VNWKPLWFXXXXXXXXXXXXFTNE-YWSAKK-MQFKNVQFPILW 2717
Q++ WEIIEG+ + + +P+ +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP N+ + + Q+ SP+ P N+ G V L E D ++ + E KL+ LE++ A N D++ + + L ASNP+L+ + NPP D T+L+ +F A +++LL+S + +A+E + + +++ + + + +++ + +L + N++L++RLNRI E+ IS + S I S D + +S+ S EG +S + F+DA E L S S+S ++D ISD + +N + R+ L +TGRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D ERM +AAFAVS YAST+YRAG+KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+N+ WQ+ R KNKFWGKS+E +P G++ V L K+ + WNKVTTCI+NI R+IEHYG++ + N S+ K+TF K + W E+ G + + + +LFGKW EG+Y GD A+CIWRPG++P +++ YYGF++FAI+LN LD L LP TD+RFRPDQR LE G + A EK +IEELQR ++ D V + P +F+K + + +++ YW +K F V P+LW
Sbjct: 34 QEADSWEIIEGLKIGQSSVQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKKARRIDLDTEENIYHLKVKSQDTFDSWVSKLRHHRLYRQNEIVRSP-------RDASLHMFPSTSTTESSPAANVTVPEGKAPQNNFLWQSPI--------PSSNSLPATCTTGQSKVAAWLLDSEEMDKCAEDLAQCQSSLIELSKLLH-NLELLQRTQSAPNFIDMQVPHSASMTPVRLHASNPNLYAD-------IEFQNPPSHVVDALEFASDYTKLQE-EFCLIAQKVHSLLKSAYNTIAIEKEKMKQMVSDQDYSGQNTQIAR-LRQSLSQALNHNSELRSRLNRIHTESVISDQVVSVNIIASPDESCEQMHVSLPLSQQVSNEG-------RLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNVSRQILNGELLGGAFRTGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPHERMALVAAFAVSGYASTYYRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPFGTVNVKLPKYGDCYVWNKVTTCIHNILSGRRWIEHYGEITIRNSKNCVSTCKMTFIKGSYWNASANEIHGVVMDQEGKVVHRLFGKWHEGLYCGDAPAAKCIWRPGSMPINYELYYGFSRFAIELNELDPVLKDFLPWTDARFRPDQRLLEEGNVEAAAMEKQRIEELQRSRRKCMEEDHVEYTPKYFRKVIDNHQKEMWISSDTYWELRKDPGFSKVDLPVLW 871
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A4W3IRY5 (Oxysterol-binding protein OS=Callorhinchus milii OX=7868 GN=osbpl6 PE=3 SV=1) HSP 1 Score: 502.286 bits (1292), Expect = 1.427e-160 Identity = 318/799 (39.80%), Postives = 455/799 (56.95%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKI------------GPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIK-SNVKIIHP-SLSASNPSLHGVSYGVSKMLSQPNPP--------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSI-VSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WEIIEG+ I +P+ +G + +RKWP+KGW K + ++NGI+ YSK+ N K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D FP + D+ A +++ LD+ P++NN ++ I V L E D ++ + E KL+Q LEI+ A N D++ + + P L ASNP+L S + QP+PP D T+L+ +F A ++ LL++ F +A+E + + LL+ + L ++ TL + QN +L++RLNRI +E+ +S + S+ + T + P + V+ +++ V N ++S + F+DA E L S S+S + D P E L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ LCEELEYS+LLD AA++ D +RM +AAFAVS YAST+YRA KPFNP++GETYE +R DKG++F +EQVSHHPP+S C+CES+ + WQ+ R KNKFWGKS+E +P G + V L K+ + WNKVTTCI+NI R+IEHYG++ + N++ K++F K W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN LD L LP TD+RFRPDQRYLE G A +EK +IEELQR
Sbjct: 39 WEIIEGLKIGQTSIQKPEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKTPNDIQKGKLHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDVFDPWVTKLRHHRLYRQNEIVRSP-------RDASFHVFPTSPNADS-----PAASSANVLDVK-----PQQNNFTLQASIPCSTSLPVSYSNSQTKVAAWLLDSEEMDKCAKDLAHCQSSLIELSKLLQ-NLEILQRTQSAPNFTDMQVPSCATLSPVRLHASNPNL---SAENEENPPQPSPPADSPDSSADYTKLQE-EFCHIAQKVHCLLKAAFNTVAIEREKLKQLLSEQEHPGHNAQL-LSLRRTLSQALNQNAELRSRLNRIHSESILSDQVVSVNIITSPDEPNDKIHVNIP---LSQQVSNESRLSMSESVSE--FFDAQEVLLSASSSENEVRDIEDNSIATVWIPNGE-------LIGGAFRNGRRTSLPAPSPDTSSINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEELEYSELLDKAAETDDPYDRMVLLAAFAVSGYASTYYRATFKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKKFIFWQDIRWKNKFWGKSMEILPVGRVNVTLPKYGDQFEWNKVTTCIHNILSGRRWIEHYGEIAIRNTKNNACICKLSFIKGTYWSSNVNEVQGFVMDQEGKVVRRLFGKWHEGLYCGVAPSAKCIWRPGSMPTDYEMYYGFTRFAIELNELDPVLKELLPPTDARFRPDQRYLEEGTTESAASEKRRIEELQR 802
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A3Q2X3J8 (Oxysterol-binding protein OS=Haplochromis burtoni OX=8153 PE=3 SV=1) HSP 1 Score: 501.516 bits (1290), Expect = 5.988e-160 Identity = 314/814 (38.57%), Postives = 466/814 (57.25%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNE---QVQDAIQASSPLDINEDDEGPKKNNTSMVDKI---GPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPP------------DMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAE-GV-INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSA---KITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRI 2567
Q++ WEIIEG+ + + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP + +D+ + V + ++ + P + P ++TS + G V E D ++ + E +L+Q LEI+ A N D++ + S S S LH + + L PP D +L+ +F A +++LL+S F +A+E + + + + + S N L +L + QN +L+ RLNRI +E+ ++ +VS + +ST D+ + G+ + + + N S ++ +E F+DA E L S S+S ++D +SD + +N M + GRR L A PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEYS+LLD AA++ D ERM +AAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG+ F +EQVSHHPPVS C+CES+N++ WQ+ R KNKFWGKS+E +P GS+ + + +F + WNKVTTC++NI R+IEHYG++ N+ SSA K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L +L LP+TD+RFRPDQRYLE G + A +EK +IE++QR+
Sbjct: 50 QEADSWEIIEGLKIGQSNVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSQDIFDAWVSKLRHHRLYRQNEIVRSP-------RDATMRTFPPSAAMDSPQPTPAVVNEVKQTKPSSLPWQPAAPSNSSTSSLPASYSNGQSKVVAWLQESEEMDKCAEELARCQSNLTELSRLLQ-SLEILQRTQSAPNFTDMQ-----VPLSASMSPVRLHSSNPNLCAELVDFQPPVSRLTDSVECASDYIKLQE-EFCIIAQKVHSLLKSAFNTVAIEKEKIKQILSDQEQPDQSAQINSLRKSLSQALSQNAELRTRLNRIHSESVLT---EQVVSVNI--------ISTPDEAGEQMGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEGSDDESYVSDVSDNISEDNASVTDNVSRQMANGDFAGSAFRNGRRSCLSAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQRMCEELEYSELLDKAAETEDPFERMVLVAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPVSACHCESKNFTFWQDVRWKNKFWGKSMEILPIGSVNLMIPRFGDQYEWNKVTTCVHNILSGRRWIEHYGEITIR-NIKSSACLCKLTFVKGNYWSSNVNEVQGFVMDQEGKVIHRLFGKWHEGVYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAIELNELCPELKDALPRTDARFRPDQRYLEEGNLEMASSEKQRIEDMQRV 837
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:103036811]) HSP 1 Score: 485.723 bits (1249), Expect = 1.246e-157 Identity = 310/820 (37.80%), Postives = 459/820 (55.98%), Query Frame = 3
Query: 231 PTNNSKLPHQ-KSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDN-----NEQVQ-DAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-----------FTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGV-----INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXX-----XXXXXXXXXXXXXXXPQIENIMKRRT----LTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
PT++ +LP ++ WEIIEG+ + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP L++ + QV+ ++ SPL N S V E AEE S + +L + + LEI+ + S + S LH + + L+ P I+ F A +++LL+S F +A+E + + +L+ + + S + ++ +L + QN +LK RLNRI +E+ ++ + S+ ++ +S D +E + + + + N S ++ +E F+DA E L S S+S + +E+ + +I+ R+ L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEY++LLD AA++ D ERM +AAFAVSAY+ST+YRAG+KPFNPI+GETYE +R DKG+ F +EQVSHHPPVS C+CES+N++ WQ+ R KNKFWGKS+E +P G++ V + + WNKVTTC++NI R+IEHYG++ + +S+ K+TF KSN W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L ++ LP TD+RFRPDQR+LE G + A AEK +IE+LQR
Sbjct: 17 PTHSLRLPLSLEADSWEIIEGLKIGQTNVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSVKKKARRIDLDTEEHIYHLKVKSPDVFDAWVCKLRHHRLYRQNEIVRSP-------RDASLRAFPPPASLESPQTTPSSQVKPSSLPWQSPLPCTTSLPPSYSNGQSKVAAWLQESEEMDKCAEELAHCQSSLI---------ELSRLLQSLEILQRTQSAPSFTEMQVPLSATRSAGRLHSSNPNLCAELADYQTPATRLTDGIECASDYIKLQEDFCVIAQKVHSLLKSAFNTVAIEKEKIKQVLSEQEQSSQSSQIV-SLRHSLSQALSQNVELKTRLNRIHSESVLTDQVVSV------------NIISSPDEASEQIHVGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYVSDVSDNISEDNASVTDIVSRQMPNGDLAGGAFRNGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAETDDPYERMALVAAFAVSAYSSTYYRAGSKPFNPILGETYECIREDKGFCFFSEQVSHHPPVSACHCESKNFTFWQDIRWKNKFWGKSMEILPIGTVNVMFPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTKSSTCICKMTFIKSNYWSSNVNEVQGFVMDQEGKVVHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAIELNELCPEMRDLLPPTDARFRPDQRFLEEGKVELASAEKQRIEDLQR 807
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:103036811]) HSP 1 Score: 484.952 bits (1247), Expect = 2.062e-157 Identity = 303/808 (37.50%), Postives = 450/808 (55.69%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNE----QVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQ-----------FTESASGIYNLLQSTFKKLALECDNV--LLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGV-----INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXX-----XXXXXXXXXXXXXXXPQIENIMKRRT----LTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
Q++ WEIIEG+ + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP L++ + + Q P + P + G V E D ++ + E +L+Q LEI+ + S + S LH + + L+ P I+ F A +++LL+S F +A+E + + +L+ + + S + ++ +L + QN +LK RLNRI +E+ ++ + S+ ++ +S D +E + + + + N S ++ +E F+DA E L S S+S + +E+ + +I+ R+ L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEY++LLD AA++ D ERM +AAFAVSAY+ST+YRAG+KPFNPI+GETYE +R DKG+ F +EQVSHHPPVS C+CES+N++ WQ+ R KNKFWGKS+E +P G++ V + + WNKVTTC++NI R+IEHYG++ + +S+ K+TF KSN W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L ++ LP TD+RFRPDQR+LE G + A AEK +IE+LQR
Sbjct: 47 QEADSWEIIEGLKIGQTNVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSVKKKARRIDLDTEEHIYHLKVKSPDVFDAWVCKLRHHRLYRQNEIVRSP-------RDASLRAFPPPASLESPQTTPSSAHETKQQVKPSSLPWQSPLPCTTSLPPSYSNGQSKVAAWLQESEEMDKCAEELAHCQSSLIELSRLLQ-SLEILQRTQSAPSFTEMQVPLSATRSAGRLHSSNPNLCAELADYQTPATRLTDGIECASDYIKLQEDFCVIAQKVHSLLKSAFNTVAIEKEKIKQVLSEQEQSSQSSQIV-SLRHSLSQALSQNVELKTRLNRIHSESVLTDQVVSV------------NIISSPDEASEQIHVGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYVSDVSDNISEDNASVTDIVSRQMPNGDLAGGAFRNGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAETDDPYERMALVAAFAVSAYSSTYYRAGSKPFNPILGETYECIREDKGFCFFSEQVSHHPPVSACHCESKNFTFWQDIRWKNKFWGKSMEILPIGTVNVMFPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTKSSTCICKMTFIKSNYWSSNVNEVQGFVMDQEGKVVHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAIELNELCPEMRDLLPPTDARFRPDQRFLEEGKVELASAEKQRIEDLQR 833
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:103036811]) HSP 1 Score: 478.019 bits (1229), Expect = 6.335e-154 Identity = 313/843 (37.13%), Postives = 459/843 (54.45%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDN-----------NEQVQ-DAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEK------LEIMAENMDDIKSNVKI----------------IHPSLSASNPS--LHGVSYGVSKMLSQPNPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL----------------TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGV-----INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXX-----XXXXXXXXXXXXXXXPQIENIMKRRT----LTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSR-KSQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
Q++ WEIIEG+ + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K K +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP L++ +QV+ ++ SPL N S V E AEE S + +L + L+++Q E+ + +D K + ++ + LSA+ + LH + + L+ P ++ E AS Y LQ F +A + ++L + +T E K VL +L + QN +LK RLNRI +E+ ++ + S+ ++ +S D +E + + + + N S ++ +E F+DA E L S S+S + +E+ + +I+ R+ L + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEY++LLD AA++ D ERM +AAFAVSAY+ST+YRAG+KPFNPI+GETYE +R DKG+ F +EQVSHHPPVS C+CES+N++ WQ+ R KNKFWGKS+E +P G++ V + + WNKVTTC++NI R+IEHYG++ + +S+ K+TF KSN W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L ++ LP TD+RFRPDQR+LE G + A AEK +IE+LQR
Sbjct: 47 QEADSWEIIEGLKIGQTNVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSVKKKARRIDLDTEEHIYHLKVKSPDVFDAWVCKLRHHRLYRQNEIVRSP-------RDASLRAFPPPASLESPQTTPSSAHETKQQVKPSSLPWQSPLPCTTSLPPSYSNGQSKVAAWLQESEEMDKCAEELAHCQSSLIELSRLL--QSLEILQRTQSAPSFTEMQSNCVDLSKKDKRVSRRWRTKSVSKDAKMQLQVPLSATRSAGRLHSSNPNLCAELADYQTP---ATRLTDGIECASD-YIKLQEDFCVIAQKVHSLLKSAFNTVAIEKEKIKQVLSEQEQSSQSSQIVSLRHSLSQALSQNVELKTRLNRIHSESVLTDQVVSV------------NIISSPDEASEQIHVGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYVSDVSDNISEDNASVTDIVSRQMPNGDLAGGAFRNGRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHMCEELEYTELLDKAAETDDPYERMALVAAFAVSAYSSTYYRAGSKPFNPILGETYECIREDKGFCFFSEQVSHHPPVSACHCESKNFTFWQDIRWKNKFWGKSMEILPIGTVNVMFPSYGDHYEWNKVTTCVHNILSGRRWIEHYGEVTIRNTKSSTCICKMTFIKSNYWSSNVNEVQGFVMDQEGKVVHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYELYYGFTRFAIELNELCPEMRDLLPPTDARFRPDQRFLEEGKVELASAEKQRIEDLQR 864
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbpl3a (oxysterol binding protein-like 3a [Source:ZFIN;Acc:ZDB-GENE-040912-77]) HSP 1 Score: 345.51 bits (885), Expect = 6.857e-106 Identity = 180/382 (47.12%), Postives = 258/382 (67.54%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQ-FSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS----AKITFHKSNSWVHQKFEVTGTISCPDSRKSQ-LFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVK-GDVNWKPLWFXXXXXXXXXXXXFTNEYWSAKK-MQFKNVQFPILW 2717
RR +LP+ +S+ +L ++L NIG+DLSKV +P+ LNEP+S LQ LCEE+EY LLD AA + D RM Y+AAFAVSAYA ++ RAG KPFNPI+GETYE RPDKG++FI+EQVSHHPPVS C+CES+N+++WQ+ R KNKFWGK++E +P G+ + L +F + N+VT+CI+NI R+IEHYG+M + + K+TF+K++S + +V ++ + R LFGKW E +++G+ +A C+WR +P+DH+++YGFTQFAI+LN LD ++ LP TD+RFRPDQR LE G ++ AE +K +IE LQR ++ +++ P +FK+ E S YW +K F + FP+LW
Sbjct: 345 RRSRLPSAC--VSEGVNLWSILYSNIGKDLSKVSMPIQLNEPISTLQRLCEEMEYCHLLDTAAHTHDPDMRMVYVAAFAVSAYACSYTRAGMKPFNPILGETYECERPDKGFRFISEQVSHHPPVSACHCESKNFTLWQDVRWKNKFWGKTMEIVPMGTTHIVLPRFGDHYELNRVTSCIHNILSGQRWIEHYGEMTIRNTAAAENAGHCKVTFYKASSRGLKVNKVEAVVTDAEGRVVHSLFGKWNEALFLGEPPSALCVWRANPMPEDHEQFYGFTQFAIELNELDENIKPFLPPTDTRFRPDQRLLEEGNVSAAEEQKERIEALQRERRRVLQENNMSHAPRFFKRSEDDAWLS---NGTYWELRKDPGFSKLDFPLLW 721 HSP 2 Score: 73.9442 bits (180), Expect = 5.229e-13 Identity = 33/77 (42.86%), Postives = 50/77 (64.94%), Query Frame = 3
Query: 387 YISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
Y +E GI+ Y+K+ K ID+GL+V++ K K ID+D++++ YHLKVK D FD WV +R+HR++RQ
Sbjct: 7 YFLLEKGILMYAKTLADLKKGKLRGRIDVGLSVMSIKKKAMCIDLDTEDSIYHLKVKTRDLFDGWVSQLRNHRVFRQ 83
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbpl3b (oxysterol binding protein-like 3b [Source:ZFIN;Acc:ZDB-GENE-090109-1]) HSP 1 Score: 344.354 bits (882), Expect = 1.737e-104 Identity = 188/379 (49.60%), Postives = 250/379 (65.96%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQV-SHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF--TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVNWKPLWFXXXXXXXXXXXXFTNEYWSAKKMQ-FKNVQFPILW 2717
RR LP+ P+ S SL N+L NIG+DLSKV +PV LNEP++ LQ LCEELEYS+LLD AA + D ERM YIA FAVS YAS++YRAG KPFNP++GETYE RPDKG++FIAEQV ++HPP+S C+ ES+N+ WQ+ R KNKFWGKS+E +P G+ V + + WNKVT+CI+NI R+IEHYG+++ +S+ K+TF K+ W EV G ++ + +LFGKW EGIY G+ A CIWR +P D+++YYGFT+FA++LN LD LP TD+RFR DQR LE G + AE +K +IE+LQR KV + N + SK +++ N YW +K F N+ P+LW
Sbjct: 440 RRSFLPSPSPNTSNISLWNILRNNIGKDLSKVAMPVQLNEPVNTLQRLCEELEYSELLDRAAHTQDPFERMVYIATFAVSGYASSYYRAGGKPFNPVLGETYECDRPDKGFRFIAEQVLTNHPPISACHAESKNFIFWQDVRWKNKFWGKSMEIVPVGTTHVIIPGLGDHYEWNKVTSCIHNILSGQRWIEHYGEISIKNSSSDICQCKVTFVKAKYWNSSVNEVEGAVTDHKGKVIHKLFGKWHEGIYCGNPPAATCIWRTNPMPPDYEQYYGFTKFALELNELDLHTKQILPPTDTRFRLDQRLLEEGNVEAAEVQKQRIEQLQR-DRRKVLEENNMA----HQPRKSKDDTWVSNNTYWELRKNPGFSNLDCPVLW 813 HSP 2 Score: 92.8189 bits (229), Expect = 8.293e-19 Identity = 46/115 (40.00%), Postives = 64/115 (55.65%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
WEI+EG+ + P+ +G + RRKWPMKGW K+ +S + S K ID+GL+V+ K K + ID+D++ YHLK K + FD WV +R HRLYRQ
Sbjct: 33 WEIVEGLRGGLGNVQEPEKQEGFMLKRRKWPMKGWHKVGVSD-------TLRSCMIEKGKLHGCIDVGLSVMAIKKKAKCIDLDAEENIYHLKFKSQELFDEWVSKLRHHRLYRQ 140
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 385.956 bits (990), Expect = 6.219e-120 Identity = 204/385 (52.99%), Postives = 267/385 (69.35%), Query Frame = 3
Query: 1593 KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDM---NFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVN--WKPLWFXXXXXXXXXXX-XFTNEYWSAKK-MQFKNVQFPILW 2717
+TGRR LPA D S L ++L KNIG+DLSKV +PV LNEPL+VLQ LCEE+EYSDLLD AA + D +RM +A FAVS YAST RAG KPFNP++GETYE +R D+G++FIAEQVSHHPP+SVC+C+S+ + +WQ+ RLKNKFWGKS+E IP G++ V L K+ + WNKVT+CI+NI G R+IEHYG++ N SN+ KI F K++ W + +V GT+ + R +LFGKW EG+Y G +ARCIWRPG++P+DH+ YYGFT+FAI+LN LD L LP TD+RFRPDQR+LE G + A+ EK +IEE QR ++ D N + P +F+K+ + S N YW +K F + PILW
Sbjct: 515 QTGRRMHLPAPAADTSSIGLWDILRKNIGKDLSKVAMPVELNEPLNVLQRLCEEMEYSDLLDRAADTDDPAQRMVLVATFAVSTYASTISRAGGKPFNPVLGETYECIREDRGFRFIAEQVSHHPPISVCHCDSKKFVLWQDVRLKNKFWGKSMEIIPVGTVNVKLLKYGDEYEWNKVTSCIHNIMGGQRWIEHYGEVIIKNKKSNV-CQCKINFIKASYWSSEANQVQGTVMDQNGRVLHRLFGKWNEGMYCGAQRSARCIWRPGSLPQDHELYYGFTRFAIELNELDPVLRPHLPPTDTRFRPDQRFLEEGNMESAQREKLRIEEFQR-EKRRLMEDKNILYTPRFFRKNITQDSREEWLMNNTYWELRKDPGFSKIDNPILW 897 HSP 2 Score: 102.834 bits (255), Expect = 1.575e-22 Identity = 42/118 (35.59%), Postives = 75/118 (63.56%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKL 626
WE+++G+ E + P +G L+ +RKWP+KGW + + +++NGI+ Y+K+ + +DLGL+V++ K K ID+D++ + YHLK K + F+ WV ++R HR +RQ+ +
Sbjct: 5 WEVVDGMSECQGSLTPPVRKEGCLHKKRKWPLKGWHQRFFTLDNGILKYAKTPIDVQRGRLHGSMDLGLSVMSIKRKAGCIDLDNEESIYHLKTKSKEHFEQWVSSLRHHRQHRQFSI 122
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbp (oxysterol binding protein [Source:ZFIN;Acc:ZDB-GENE-090312-18]) HSP 1 Score: 201.445 bits (511), Expect = 1.749e-54 Identity = 143/419 (34.13%), Postives = 218/419 (52.03%), Query Frame = 3
Query: 1593 KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCES-ENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKF------------EVTGTISCPDSRKSQLF-GKWTEG----------------------IYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRI----------ALAKVKGDV-----NWKPLWFXXXXX--XXXXXXXFTNEYWSAKKMQ 2687
K RR ++P +P+ S +L +++ IG+DLSK+ +PV NEPLS+LQ L E+LEY DLLD AAK SLE++ Y+AAF+VS+Y++T YR G KPFNP++GET+E R ++ G++ I EQVSHHPP + + +S W +WQE + +KF GK + IP G++ W KVTT ++NI +I+ GD++ I H + KF +V+G + + + G W E +Y A+ +W+ +P++ D Y FT+ A+ LN + +A TDSR RPDQR +E G EA AEK ++EE QR+ + A+ GD +++P+WF++ E ++ S + YW K+ Q
Sbjct: 331 KKQRRARIPD-KPNYS-LNLWSIMKNCIGKDLSKIPMPVNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFSVSSYSTTVYRTG-KPFNPLLGETFELDRLEECGYRSICEQVSHHPPAAAHHVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNHYTWKKVTTTVHNIIVGRLWIDQSGDID----------IVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPAKHLWKRYPLPENSDNMYYFTELALTLNETEEGVAP----TDSRLRPDQRLMENGKWDEANAEKQRLEEKQRLVRRRREAELASAAEPNGDAGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQ 732
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 196.438 bits (498), Expect = 1.976e-54 Identity = 142/344 (41.28%), Postives = 212/344 (61.63%), Query Frame = 3
Query: 1110 GIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQ---QNNDLKARLNRIKAEASISYSIPSIV-STDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQE--KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKK 2096
++ L+S F +A+E + + + + +VL K L Q QN DL++RL+RI A+++++ + +I+ S D P ++ ++ ++ + N +SR +S + F+DA E L S S+S ++D +SD + +NI L+ + + GRR LPA PD S SL N+L NIG+DL+KV +PV LNEPL+ LQ LCEELEYS+LL+ A+ + D +RM AAFAVSAYA T+YR+G KPFNP++GETYE +R DKG++F+AEQVSHHPP+S C+CES+ + +WQ+ R KNKFWGKS+E +P G++ + L K
Sbjct: 167 AVHVTLKSVFNSVAIEKEKLRQVACEHEAAGAGHAAHVLALKKALAQATAQNGDLRSRLSRIHADSNLTEPLVNIILSPDM--PYKNQGTHSTLPLLSRVIANHESR-LSVSESVSEFFDAQEVLISASSSENEPSDDESYVSDVSDNVSEDNISVTDGAPQTFVNSALSTREGGFRNGRRSFLPAPCPDTSGVSLWNILRNNIGKDLAKVSMPVELNEPLNTLQRLCEELEYSELLEQASDTEDPAQRMVLAAAFAVSAYAPTYYRSGNKPFNPVLGETYECIREDKGFRFVAEQVSHHPPISACHCESKTFVLWQDVRWKNKFWGKSMEILPLGTVSLNLPK 507
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl1a (oxysterol binding protein-like 1A [Source:ZFIN;Acc:ZDB-GENE-050208-657]) HSP 1 Score: 188.348 bits (477), Expect = 1.967e-52 Identity = 141/402 (35.07%), Postives = 199/402 (49.50%), Query Frame = 3
Query: 1605 RDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRL------KNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS-SAKITFHKSNSWVHQKFEVTGTISCPDSRK--SQLFGKWTE-------GIY------------------------------------------------VGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALA-KVKGDVNWKPLWF 2615
R LPA S FS+ + L + IG +LSK+ +PVI NEPLS LQ LCE +E++ L+ A SS S+ERM +AAFAVSA AS + R G KPFNP++GETYE VR D G++ ++EQVSHHPP+S + E N ++F K KFWGKS+EA P G + + L ++ E W + C++N+ +IE YG + T++ A ++F N + DS+K S ++GKWTE GIY V ++ +WR P + + Y FT FA+ LN ++ ++ L TD R RPD + +E G I A EK ++EE QR A + K + W WF
Sbjct: 1 RTSLPAPMFSRSNFSIWSFLRRCIGMELSKITMPVIFNEPLSFLQRLCEYMEHTYLIHKANTSSSSIERMQCVAAFAVSAVASNWERTG-KPFNPLLGETYEMVREDLGFRLVSEQVSHHPPISAFFAEGLN----KDFVFHGSVYPKLKFWGKSVEAEPRGIITLELPRYGEAYTWTNPSCCVHNVIVGKLWIEQYGTVEITNHKRGFKASLSFRARNITKRKSRRPLSAFRI-DSKKKVSVIYGKWTEVLWSVDPGIYEVGKKNDKKSTEKLAKLVAAESSGPSGQQAEADEADDIPTPEVPETVTVLPGSKLLWRVHPRPANSTQMYNFTSFALTLNEMEKEMEGLLAPTDCRLRPDMKAMEQGDIDLAGEEKNRLEEKQRAARKQRAKTEEEWHTRWF 396
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 118.242 bits (295), Expect = 3.479e-30 Identity = 50/115 (43.48%), Postives = 77/115 (66.96%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQ 617
WEIIEG+ ++ +P+ +G L +RKWP+KGW K + +ENGI+ Y+KS + + ID+GL+V++ K K +RID+D++ YHLK+K + FD WV +R+HRL+RQ
Sbjct: 1 WEIIEGLRSGQPDVHKPERHEGFLLKKRKWPLKGWHKRFFVLENGIVKYAKSPAEVQRGKLHGSIDIGLSVMSIKKKSRRIDLDTEEYIYHLKIKSQEMFDVWVSKLRNHRLFRQ 115
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH2 (Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]) HSP 1 Score: 201.445 bits (511), Expect = 1.605e-53 Identity = 138/416 (33.17%), Postives = 207/416 (49.76%), Query Frame = 3
Query: 1548 IENIMKRRTLTLYQE------KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLK----KFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQ-KFEVTGTISCPDSRKSQLF-GKWTEGIYV------GD----NARCIWRPGAIPKDH-------------DKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAK-VKGDVNWKPLWFXXXXXXXXXXX--XFTNEYWSAKK 2681
+ + KR+ L +E + G R +L + D + SL +L +G+D++++ LPV NEP S+LQ + E+LEYS+LLD AA DS R Y+AAF S+YAST R KPFNP++GET+EY RPDK ++F EQVSHHPP+S + ES W W E + KF G+S G + L+ + E W K + I N ++++G++N ++ + K+ W +E+TG + +K + G W E I+ GD R G P D ++ + T FAI LN L LP TD+R RPDQR +E G EA EK ++EE QR A K + ++ + P WF + +++ +T +YW ++
Sbjct: 858 VTTVQKRKEEYLLKEGSYLGYEDGIRKRLSMDKDDRPKISLWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVA-KPFNPLLGETFEYSRPDKQYRFFTEQVSHHPPISATWTESPRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRSSGAYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKTRTAASAGNGPTDDGTKFLIWKANDRPEEPFNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNLEYHPQWFVRDTHPITKAKYWRYTGKYWVKRR 1272
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH3 (Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding [Source:SGD;Acc:S000001115]) HSP 1 Score: 195.667 bits (496), Expect = 5.904e-52 Identity = 116/318 (36.48%), Postives = 168/318 (52.83%), Query Frame = 3
Query: 1584 YQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGT----KPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSN--SWVHQKFEVTGTISCPDS--RKSQLFGKWTEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
Y + RR+ +P + S SL++ L KN+G+DLS + +PV NEP+S+LQ++ E EY+ LL A + D + +++AFA+S + YR T KPFNP++ ET+E +R D G++ I+E+VSH PPV + E +W KFWGKSIE G LR+ K E W + TT + N+ RY+E + S+ + I F K+ S + F+V+ I P S +K L GKWT+ + IW G + + K YGFT+F +LN + LP TDSR RPD R E G
Sbjct: 623 YPKSVTRRNDIP--EAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPI---TFVSAFAISFLS--IYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVS-IIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEG 932
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: SWH1 (Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication [Source:SGD;Acc:S000000081]) HSP 1 Score: 186.808 bits (473), Expect = 5.911e-49 Identity = 139/422 (32.94%), Postives = 211/422 (50.00%), Query Frame = 3
Query: 1542 PQIE---NIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFN------ETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQ-KFEVTGTISCPDSRKS-QLFGKWTEGIYVGDNARCIWRPGAI--------------PK-DHDKY------------YGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALA--KVKGDVNWKPLWFXXXXXXXXXXX--XFTNEYWSAKK 2681
PQ+E ++K + Y++ R KL + + + L ++L +G+DL+K+ LPV NEP S+LQ + E++EYS +LD AA DS RM Y+AAF S YAST R +KPFNP++GET+EY R D ++F EQVSHHPP+S + ES W + E + + F G++ G + ++ + ET W K + I +++ GD+ T++ + +K++ W +EV G + D +K L G W + IY + R G + PK D K+ + T FA+ LN L L L TDSR RPDQR +E G +A AEK ++E QR A + KG+ ++P WF + E ++S +F EYW+ +K
Sbjct: 763 PQVEKKNQLLKEGSFVGYEDPV--RTKLALDEDNRPKIGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRV-SKPFNPLLGETFEYARTDGQYRFFTEQVSHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWVLGGHWNDSIY---GKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKEREQKGE-EYRPKWFVQEEHPVTKSLYWKFNGEYWNKRK 1177
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH7 (Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication [Source:SGD;Acc:S000001043]) HSP 1 Score: 74.7146 bits (182), Expect = 1.765e-14 Identity = 74/251 (29.48%), Postives = 120/251 (47.81%), Query Frame = 3
Query: 1638 SQFSLINLLCK-NIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYE--YVRPDKGWKF-IAEQVSHHPPVSVCY--CESENWSIWQEFRLKNKFWGKSIEAIPTG-SLRVYLKKFNETVHWNKVTTCIYNI------FGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFE-VTGTISCPDSRK-SQLFGKWTEGIYVGD 2345
Q L+N++ + G DLS++ LP + E S+L+ + +L++ D+L A + D L+R + A+ ++ + RA KP NPI+GE + + P+K F IAEQ SHHPP S + N + K+KF G S A+ G ++ +L + K T N+ FG R IE GD I F K+ ++ ++ + GTI D ++ Q+ GKW + +Y+ D
Sbjct: 47 GQSILLNIISQLKPGCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGW-HIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPPESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMR-IE-LGDHMVIMGPKYQVDIEF-KTKGFISGTYDAIEGTIKDYDGKEYYQISGKWNDIMYIKD 293
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH6 (Member of an oxysterol-binding protein family; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication [Source:SGD;Acc:S000001711]) HSP 1 Score: 63.929 bits (154), Expect = 5.825e-11 Identity = 64/236 (27.12%), Postives = 110/236 (46.61%), Query Frame = 3
Query: 1677 GRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGE--TYEYVRPDKGWKF-IAEQVSHHPPVSVCYCESENWSIWQEFRL--KNKFWGKSIEAIPTGSLRVY---LKKFN---ETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFE-VTGTISCPDSRK-SQLFGKWTEGIYVGD 2345
G DL+++ LP + E S+L+ + +L++ + L A D L+R Y+ + ++ + +A KP NP++GE T + P+K + I+EQ SHHPP + SI + + K++F G S A+ GS + +K N E + + I IE GD + N A I F K+ +V ++ + GT+ D ++ GKW + +Y+ D
Sbjct: 61 GCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGW-HIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIE-LGDHMIIKSPNFQADIEF-KTKGYVFGTYDAIEGTVKDYDGNAYYEISGKWNDVMYLKD 293
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO41441 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S4A2]) HSP 1 Score: 215.698 bits (548), Expect = 7.058e-62 Identity = 122/324 (37.65%), Postives = 179/324 (55.25%), Query Frame = 3
Query: 1569 RTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKF-EVTGTISCPDSR-KSQLFGKWTEGIYV-------GDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
R T++ ++ RR LPA + S SLI+ + +G+D++KV +PV NEP+S LQ L E+LEY+D+L+ A ++L ++ ++AAFA S YA+ R KPFNP++GET+EY+ D G+ IAEQVSHHPP+S + ES +W WQE++L KF G+ + IPTG + K W K T I+NI + Y++ GDM T++ V F ++ G + P+ + + + G W + + D++ +W A P D K Y FT+F I LN D D T P TD R RPD R LE+G
Sbjct: 29 REHTIFTKRRPRRTALPATRERSSIRSLISFMKTVVGKDMTKVTMPVHFNEPVSFLQRLSEDLEYADILNRACVCKNNLVKLAHVAAFASSTYATVLSRFW-KPFNPLLGETFEYIDNDNGFALIAEQVSHHPPISALHAESSHWVFWQEYKLDTKFRGQFFKVIPTGHCHLKFKTNGHHFSWKKPVTTIHNILVGSLYVDQEGDMVVTNHTTKETCTVHFMPVRKVQDNFKKLKGEVKDPEGKVRYVIEGSWDKSLECIPQDTGFNDDSIDLWTAVARPDDSYKMYAFTRFTIQLN--DPDYGVTCP-TDCRNRPDIRQLELG 348
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO39767 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S940]) HSP 1 Score: 198.364 bits (503), Expect = 4.144e-56 Identity = 131/363 (36.09%), Postives = 181/363 (49.86%), Query Frame = 3
Query: 1638 SQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFH-KSNSWVHQKF-EVTGTISCPDSRKSQ--LFGKWTEGIYV--------------------------------GDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIA-LAKVKGDVNWKPLWF 2615
++FS+ +L + IG+DLS++ +PVI NEPL+ LQ + E +EYS+LL AA D R+ KPFNP++GETYE VRP G++ +AEQVSHHPP++ CES+++ + K KFWGK +E P G + + K NE WN V +C++NI +IE YG + +S L+S + T H K W ++ +V TI C +K + L G WT+ I + +W P + Y FT FA+ LN L TLP TDSR RPD R LE G + A AEK ++EE QR A + K D W P WF
Sbjct: 5 NEFSVWTVLKQCIGKDLSRITMPVIFNEPLTFLQRITEYMEYSELLHTAASQDDPTRRLQV-----------------GKPFNPLLGETYELVRP--GFRLVAEQVSHHPPITALQCESDDFIFHVTVQPKLKFWGKGVEVQPKGMVTLKFPKHNEVYTWNNVNSCVHNIIVGQLWIEQYGQIEISS-LSSGDRATIHFKPAGWFGKELNKVEATIHCAQDKKKRYTLKGDWTDKITCYRSETHVTRKQSKRGKQDFEIASTSSSETSLELHSPVTLWTCSHRPPHSKEMYNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKSDQEWAPRWF 347
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO44125 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7RWH9]) HSP 1 Score: 201.83 bits (512), Expect = 2.278e-54 Identity = 129/341 (37.83%), Postives = 183/341 (53.67%), Query Frame = 3
Query: 1605 RDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVR-PDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFE------------VTGTISCPDSRKSQLF---GKWTEGIYV---------GDNAR---------------CIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLE 2507
R +P +PDIS +L ++L IG++L+K+ +PV NEPLS+LQ + EELEYS++LD AA + SLE+M Y+AAF VS+Y++T R KPFNP++GET+E R D GW+ +AEQVSHHPP S + E ++W WQEF +KF GK ++ IP G + K W KVTT ++NI +I+ G+M+ I H +N H K++ VTG ++ DS K+ + G W I G A+ +W+ P +++K Y T FAI LN + +A TDSRFRPDQR +E
Sbjct: 327 RTSIPP-RPDIS-INLWSILKNCIGKELTKIPMPVNFNEPLSMLQRITEELEYSEVLDKAAACTSSLEQMCYVAAFTVSSYSTTSNRT-NKPFNPLLGETFECDRSEDYGWRSLAEQVSHHPPASAFHAEHKDWIFWQEFSATSKFRGKYLQIIPQGIAHLKFIKSGNHYTWRKVTTTVHNIIVGKLWIDQSGEMD----------IANHTTNENCHLKYDAYNYFGRDTPRKVTGVVT--DSTKTVRYVISGTWDNKIEAAKVVYLKSPGVKAQGSSSQKGQPQTLPPVVLWKRVLPPPENEKMYAMTSFAITLNEPEDHVAP----TDSRFRPDQRLME 648
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO47800 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7RL46]) HSP 1 Score: 85.5001 bits (210), Expect = 1.813e-17 Identity = 73/268 (27.24%), Postives = 122/268 (45.52%), Query Frame = 3
Query: 1650 LINLLCK-NIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFY--RAGT---KPFNPIIGETY-------------------------EYVRPDKGWKFIAEQVSHHPPVSVCYCESE------NWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTS-NLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRK--SQLFGKWTEGI 2333
+++LL + +G DL+KV LP + EP S+L+M + + D+ A + +R+ + F Y ++F+ R G+ KP+NPI+GET+ + D+G +F+AEQ+SHHPPVS Y E N IW K+KF+G SI G + L + E H+ + +I + ++E G ++ T +A +TFH + + VTG + + K ++ G+W I
Sbjct: 81 ILHLLSQLKLGMDLTKVVLPTFILEPRSLLEMYADFFAHPDMFIRIADGLTAEDRILAVLEF----YLTSFHVGRKGSLAKKPYNPILGETFTCSWDVREECSTGMERNPLNLANDVSVMEDDRGLRFVAEQISHHPPVSGFYAECPRKKICLNAHIWT----KSKFYGMSIGVANVGEAVITLLEHEEEYHFTFPSAFCRSIL-TFPWVELGGKLHITCPKTGYNASVTFHTKPFYGGKLHRVTGEVKNASTGKVICKVAGEWNGKI 339
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO35914 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7SK18]) HSP 1 Score: 81.6481 bits (200), Expect = 6.667e-16 Identity = 59/163 (36.20%), Postives = 87/163 (53.37%), Query Frame = 3
Query: 1647 SLINLLCKNI--GRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFY---RAGTKPFNPIIGETYE-YVRPDKGWK--FIAEQVSHHPPVSVCYCES--ENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNE 2105
S++ L K + G DLS+V LP + EP S L L + ++D+L AA + RM + + Y S FY + KP+NPIIGE + Y + +G + F++EQVSHHPPVS Y + + + I K+KF+G S AI G+ + L +F E
Sbjct: 242 SILWALLKQVKPGMDLSRVTLPTFILEPRSFLDKLSDFYYHTDILSRAACEENPYSRMKEV----IRWYLSGFYKKPKGLKKPYNPIIGEMFRCYWQHPQGSRTFFVSEQVSHHPPVSAFYVSNRQDGFVINGAILAKSKFYGNSSSAILDGAATLALLRFGE 400
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:101163778]) HSP 1 Score: 493.426 bits (1269), Expect = 2.860e-160 Identity = 302/803 (37.61%), Postives = 454/803 (56.54%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPK-------------KNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKI-IHP-SLSASNPSLHGVSYGVSKMLSQPNP-----------PDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAE-GV-INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
Q+S WEIIEG+ + + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP + +++ S+P + E P ++ G V E D ++ + E +L+Q LEI+ A N D++ + + P L +SNP+L ++++ P P D +L+ +F A +++LL+S F +A+E + + + + + ++ N L +L + QN +L+ RL+RI +E+ ++ +VS + +ST D+ + + G+ + + + N S ++ +E F+DA E L S S+S ++D +SD + +N + + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEYS+LLD AA++ D ERM IAAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG+ F +EQVSHHPP+S C+CES+N++ WQ+ R KNKFWGKS+E +P GS+ V + +F + WNKVTTC++NI R+IEHYG++ + +S+ K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L +L LP+TD+RFRPDQRYLE G
Sbjct: 48 QESDSWEIIEGLKIGQSHVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSQDIFDAWVSKLRHHRLYRQNEIVRSP-------RDATMRTFPPSATIES--------PLSAPCVVKEAKAKPSGLLWQPAAPSSSSSSSLPASYSNGQSKVAAWLQDSEEMDKCAEELARCQSNLTELSRLLQ-SLEILQRTQSAPNFTDMQVPLSASMSPVRLHSSNPNL------CAELVDYPPPVSCLSDNMEYASDYIKLQE-EFCTIAQKVHSLLKSAFNTVAIEKEKIKQILSEQEQSDQAVQINSLRKSLSQALSQNAELRTRLSRIHSESVLA---EQVVSVNI--------ISTPDEAVEQMGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEGSDDESYVSDVSDNISEDNASVTDNVSRQIANGDFAGSSFRNGRRTYLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQRMCEELEYSELLDKAAETEDPFERMVLIAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCESKNFTFWQDVRWKNKFWGKSMEILPIGSVNVMIPRFGDHYEWNKVTTCVHNILSGRRWIEHYGEITIRNTKSSACLCKLTFVKGNYWSSNVNEVQGFVMDQEGKVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYEMYYGFTRFAIELNELCPELKDVLPRTDARFRPDQRYLEEG 816
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:101163778]) HSP 1 Score: 490.345 bits (1261), Expect = 3.485e-159 Identity = 299/789 (37.90%), Postives = 449/789 (56.91%), Query Frame = 3
Query: 261 KSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIM-----AENMDDIKSNVKI-IHP-SLSASNPSLHGVSYGVSKMLSQPNP-----------PDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAE-GV-INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
+S WEIIEG+ + + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S +D + FP + ++ + S L ++ G V E D ++ + E +L+Q LEI+ A N D++ + + P L +SNP+L ++++ P P D +L+ +F A +++LL+S F +A+E + + + + + ++ N L +L + QN +L+ RL+RI +E+ ++ +VS + +ST D+ + + G+ + + + N S ++ +E F+DA E L S S+S ++D +SD + +N + + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEYS+LLD AA++ D ERM IAAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG+ F +EQVSHHPP+S C+CES+N++ WQ+ R KNKFWGKS+E +P GS+ V + +F + WNKVTTC++NI R+IEHYG++ + +S+ K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L +L LP+TD+RFRPDQRYLE G
Sbjct: 55 ESDSWEIIEGLKIGQSHVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSQDIFDAWVSKLRHHRLYRQNEIVRSP-------RDATMRTFPPSAT------IESPLSPSGLLWQPAAPSSSSSSSLPASYSNGQSKVAAWLQDSEEMDKCAEELARCQSNLTELSRLLQ-SLEILQRTQSAPNFTDMQVPLSASMSPVRLHSSNPNL------CAELVDYPPPVSCLSDNMEYASDYIKLQE-EFCTIAQKVHSLLKSAFNTVAIEKEKIKQILSEQEQSDQAVQINSLRKSLSQALSQNAELRTRLSRIHSESVLA---EQVVSVNI--------ISTPDEAVEQMGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEGSDDESYVSDVSDNISEDNASVTDNVSRQIANGDFAGSSFRNGRRTYLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQRMCEELEYSELLDKAAETEDPFERMVLIAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCESKNFTFWQDVRWKNKFWGKSMEILPIGSVNVMIPRFGDHYEWNKVTTCVHNILSGRRWIEHYGEITIRNTKSSACLCKLTFVKGNYWSSNVNEVQGFVMDQEGKVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYEMYYGFTRFAIELNELCPELKDVLPRTDARFRPDQRYLEEG 811
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbpl3b (oxysterol binding protein like 3 [Source:NCBI gene;Acc:101160345]) HSP 1 Score: 442.58 bits (1137), Expect = 7.956e-141 Identity = 307/876 (35.05%), Postives = 449/876 (51.26%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYF--PGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSM-----------VDKIGPELVRTMTLAEETNDDIPS--------SVSTGFVLINEDL------KLIQEKLEIMAENMD-----DIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQP--NPPDMTQLK------MIQFTESASGIYNLLQSTFKKL--ALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTG-------RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS---SAKITFHKSNSWVHQKFEVTGTISCPDSRKS---QLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVNWKPLWFXXXXXXXXXXXXFTNEYWSAKK-MQFKNVQFPILW 2717
WE++EG+ + + P +G + +RKWPMKGW K Y ++ G + Y KS + K ID+G +V+ K K + ID+D++ YHLKVK + FD WV N+R HRLYRQ +S N K C ++ P + L + ++ + ++ P +N+ +DK +L + E N + + S + L N K +Q K + D + N+ L ASNP+L + K +P +P D+ +L+ F S I + L S ++L L+ + L T+ N+ TL QN++L+ RL++I +E+ I ++LS D + + N S + + F+DA E L S S+S +ED ISD + ++N+ +G RR LPA P+ S+ N+L NIG+DLSKV +PV LNEPL++LQ LCEELEYS+LLD AA + D ERM +IA F VS YAS++YR G KPFNP++GET+E RPDKG++F+AEQVSHHPP+S C+ ES+N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R IEHYG+++ N NS KITF K++ W + EV GTI+ D++ ++FGKW E ++ GD +A+CIWR A+P +H++YYGFT+FAI+LN LD L LP TD+R R DQR LE G + AE +K +IE+LQR ++ + F + +T YW ++ F ++ FP LW
Sbjct: 35 WEMVEGLSGILSNAMEPQKQEGYMLKKRKWPMKGWHKRYFFLDKGTLKYGKSRSDIEKGKLHGCIDVGFSVMAIKKKAKCIDLDAEENIYHLKVKTEEMFDEWVSNLRHHRLYRQ------NVSTIPNEKSFCFPHYPSPNSPTLADAALIRRRMSVRRQSTVHPAGAFPLGSNSQAKVVAWLQSSEEMDKCSKDLSVCESYLLELNHMLKNMEVLHRTYSAPSIQALQNSTFNSPKKEKRLQRKWRAKTYSKDVKTTLQVPGNISSGSTRLHASNPNLSTAALLNGKADPEPLDSPFDVAKLQEDFYSVAANFHASMKSIMSSLTSERERLRQCLDHETFLPTSPQVV--------NLKNTLAAALAQNSELRERLSKIHSESHI-----------VEPTQKNLSAPVQDCMDNSHTLVHQASNESRASVADSISEFFDAQEVLLSASSSENEISEDDSYISDISDTISVDNLSNDLETDRSNSGSGDGMVVCRRRSCLPAFTPNGGSISMWNILRNNIGKDLSKVAMPVALNEPLNMLQRLCEELEYSELLDRAANTHDPYERMMFIATFVVSGYASSYYRTGGKPFNPVLGETFECNRPDKGFRFVAEQVSHHPPISACHAESKNFVFWQDVRCKNKFWGKSLEIVPVGTTHVTLPGFGDHYEWNKVTSCIHNILSGQRRIEHYGEISI-KNTNSDICQCKITFIKTSYWSSRVNEVEGTIT--DNKGKVIHRIFGKWHEAVFCGDPPSAKCIWRANAMPVNHEQYYGFTKFAIELNELDPSLTPLLPPTDTRRRVDQRLLEEGNLEAAEEQKQRIEQLQRDRRKVLEDNKEVHQPKFFSKSKDDTWVSNYT--YWELREDPGFVHIDFPTLW 880
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbpl3b (oxysterol binding protein like 3 [Source:NCBI gene;Acc:101160345]) HSP 1 Score: 440.269 bits (1131), Expect = 3.697e-140 Identity = 300/824 (36.41%), Postives = 432/824 (52.43%), Query Frame = 3
Query: 273 WEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYF--PGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSM-----------VDKIGPELVRTMTLAEETNDDIPS--------SVSTGFVLINEDL------KLIQEKLEIMAENMD-----DIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQP--NPPDMTQLK------MIQFTESASGIYNLLQSTFKKL--ALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTG-------RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNS---SAKITFHKSNSWVHQKFEVTGTISCPDSRKS---QLFGKWTEGIYVGD--NARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQR 2564
WE++EG+ + + P +G + +RKWPMKGW K Y ++ G + Y KS + K ID+G +V+ K K + ID+D++ YHLKVK + FD WV N+R HRLYRQ +S N K C ++ P + L + ++ + ++ P +N+ +DK +L + E N + + S + L N K +Q K + D + N+ L ASNP+L + K +P +P D+ +L+ F S I + L S ++L L+ + L T+ N+ TL QN++L+ RL++I +E+ I + T N LS D + + N S + + F+DA E L S S+S +ED ISD + ++N+ +G RR LPA P+ S+ N+L NIG+DLSKV +PV LNEPL++LQ LCEELEYS+LLD AA + D ERM +IA F VS YAS++YR G KPFNP++GET+E RPDKG++F+AEQVSHHPP+S C+ ES+N+ WQ+ R KNKFWGKS+E +P G+ V L F + WNKVT+CI+NI R IEHYG+++ N NS KITF K++ W + EV GTI+ D++ ++FGKW E ++ GD +A+CIWR A+P +H++YYGFT+FAI+LN LD L LP TD+R R DQR LE G + AE +K +IE+LQR
Sbjct: 35 WEMVEGLSGILSNAMEPQKQEGYMLKKRKWPMKGWHKRYFFLDKGTLKYGKSRSDIEKGKLHGCIDVGFSVMAIKKKAKCIDLDAEENIYHLKVKTEEMFDEWVSNLRHHRLYRQ------NVSTIPNEKSFCFPHYPSPNSPTLADAALIRRRMSVRRQSTVHPAGAFPLGSNSQAKVVAWLQSSEEMDKCSKDLSVCESYLLELNHMLKNMEVLHRTYSAPSIQALQNSTFNSPKKEKRLQRKWRAKTYSKDVKTTLQVPGNISSGSTRLHASNPNLSTAALLNGKADPEPLDSPFDVAKLQEDFYSVAANFHASMKSIMSSLTSERERLRQCLDHETFLPTSPQVV--------NLKNTLAAALAQNSELRERLSKIHSESHI------VEPTQKN-----LSAPVQDCMDNSHTLVHQASNESRASVADSISEFFDAQEVLLSASSSENEISEDDSYISDISDTISVDNLSNDLETDRSNSGSGDGMVVCRRRSCLPAFTPNGGSISMWNILRNNIGKDLSKVAMPVALNEPLNMLQRLCEELEYSELLDRAANTHDPYERMMFIATFVVSGYASSYYRTGGKPFNPVLGETFECNRPDKGFRFVAEQVSHHPPISACHAESKNFVFWQDVRCKNKFWGKSLEIVPVGTTHVTLPGFGDHYEWNKVTSCIHNILSGQRRIEHYGEISI-KNTNSDICQCKITFIKTSYWSSRVNEVEGTIT--DNKGKVIHRIFGKWHEAVFCGDPPSAKCIWRANAMPVNHEQYYGFTKFAIELNELDPSLTPLLPPTDTRRRVDQRLLEEGNLEAAEEQKQRIEQLQR 830
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbpl6 (oxysterol binding protein like 6 [Source:NCBI gene;Acc:101163778]) HSP 1 Score: 395.201 bits (1014), Expect = 1.748e-122 Identity = 215/495 (43.43%), Postives = 314/495 (63.43%), Query Frame = 3
Query: 1089 QFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLL-TLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAE-GV-INRDSRNISNVTTTEM---FYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENI---------MKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS--AKITFHKSNSWVHQKFEVTGTISCPDSRK-SQLFGKWTEGIYVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMG 2513
+F A +++LL+S F +A+E + + + + + ++ N L +L + QN +L+ RL+RI +E+ ++ +VS + +ST D+ + + G+ + + + N S ++ +E F+DA E L S S+S ++D +SD + +N + + GRR LPA PD S +L N+L NIG+DLSKV +PV LNEPL+ LQ +CEELEYS+LLD AA++ D ERM IAAFAVS Y+ST+YRAG+KPFNP++GETYE +R DKG+ F +EQVSHHPP+S C+CES+N++ WQ+ R KNKFWGKS+E +P GS+ V + +F + WNKVTTC++NI R+IEHYG++ + +S+ K+TF K N W EV G + + + +LFGKW EG+Y G +A+CIWRPG++P D++ YYGFT+FAI+LN L +L LP+TD+RFRPDQRYLE G
Sbjct: 364 EFCTIAQKVHSLLKSAFNTVAIEKEKIKQILSEQEQSDQAVQINSLRKSLSQALSQNAELRTRLSRIHSESVLA---EQVVSVNI--------ISTPDEAVEQMGIPLTQQASNESRLSMSESVSEFFDAQEVLLSASSSENEGSDDESYVSDVSDNISEDNASVTDNVSRQIANGDFAGSSFRNGRRTYLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQRMCEELEYSELLDKAAETEDPFERMVLIAAFAVSGYSSTYYRAGSKPFNPLLGETYECIREDKGFCFFSEQVSHHPPISACHCESKNFTFWQDVRWKNKFWGKSMEILPIGSVNVMIPRFGDHYEWNKVTTCVHNILSGRRWIEHYGEITIRNTKSSACLCKLTFVKGNYWSSNVNEVQGFVMDQEGKVIHRLFGKWHEGLYCGVPPSAKCIWRPGSMPTDYEMYYGFTRFAIELNELCPELKDVLPRTDARFRPDQRYLEEG 847 HSP 2 Score: 124.02 bits (310), Expect = 2.091e-28 Identity = 57/126 (45.24%), Postives = 82/126 (65.08%), Query Frame = 3
Query: 258 QKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNS 635
Q+S WEIIEG+ + + RPD +G + +RKWP+KGW K + ++NGI+ YSKS K ID+GL+V++ K + +RID+D++ YHLKVK D FD WV +R HRLYRQ +++ S
Sbjct: 48 QESDSWEIIEGLKIGQSHVQRPDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDTQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKSQDIFDAWVSKLRHHRLYRQNEIVRS 173
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000046022.1 (SMESG000046022.1) HSP 1 Score: 1667.51 bits (4317), Expect = 0.000e+0 Identity = 870/873 (99.66%), Postives = 871/873 (99.77%), Query Frame = 3
Query: 99 MDTESEEESEYNFTGPWSTSQXXXXXXXXXXXXXXEKHKKPTDNPTNNSKLPHQKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDINEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSNVKIIHPSLSASNPSLHGVSYGVSKMLSQPNPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNVLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLXXXXXXXXXXXXXXXXXXXXXXXPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRKSQLFGKWTEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQRIALAKVKGDVNWKPLWFXXXXXXXXXXXXFTNEYWSAKKMQFKNVQFPILW 2717
MDTESEEESEYNFTGPWSTSQNNFNDKFNKNSKDDEKHKKPTDNPTNNSKLPHQKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLD NEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSNVKIIHPSLSASNPSLHGVSYG+SKMLSQPNPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKN LLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLESDSASSISETEDIDEISDAEEEPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRKSQLFGKWTEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLITEAEAEKTKIEELQRIALAKVKGDVNWKPLWFKKHESSKSESYEFTNEYWSAKKMQFKNVQFPILW
Sbjct: 1 MDTESEEESEYNFTGPWSTSQNNFNDKFNKNSKDDEKHKKPTDNPTNNSKLPHQKSFGWEIIEGVVENSNEILRPDPTKGLLYVRRKWPMKGWGKIYISMENGIMAYSKSSNQFAKRIFLREIDLGLAVVTYKAKRQRIDIDSDNAFYHLKVKESDKFDFWVQNIRSHRLYRQWKLMNSGLSIEKNMKDECSKYFPGNIKLDNNEQVQDAIQASSPLDSNEDDEGPKKNNTSMVDKIGPELVRTMTLAEETNDDIPSSVSTGFVLINEDLKLIQEKLEIMAENMDDIKSNVKIIHPSLSASNPSLHGVSYGISKMLSQPNPPDMTQLKMIQFTESASGIYNLLQSTFKKLALECDNVLLTTASTTKRESSLSKNFLLTLKELTQQNNDLKARLNRIKAEASISYSIPSIVSTDFNGPLRSLSVSTSDDYIAEGVINRDSRNISNVTTTEMFYDAAEFLESDSASSISETEDIDEISDAEEEPQIENIMKRRTLTLYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDSRKSQLFGKWTEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLITEAEAEKTKIEELQRIALAKVKGDVNWKPLWFKKHESSKSESYEFTNEYWSAKKMQFKNVQFPILW 873
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 214.157 bits (544), Expect = 1.588e-57 Identity = 128/332 (38.55%), Postives = 190/332 (57.23%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCES-ENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF-------TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDS-RKSQLFGKW-----------------TEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGL 2516
RR K+ +P++S +L ++ IG++LSK+ +PV NEPLS++Q L E+ EYSD LDAAA+ +DSLE+++++AAF VS+Y++T R G KPFNP++GET+E+ R D GW+ +AEQVSHHPP + +CES + W WQEF + +KF GK + IP G + +K N W KVT+ ++NI +I+++G+M+ T +LN A F K + VTG I+ D K L G W + ++ A +W P+ + Y FT FA++LN + ++A TDSR RPDQR +E G
Sbjct: 501 RRTKI-TPRPNMS-INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTG-KPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPA-----RRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAP----TDSRLRPDQRLMETGF 820
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 214.157 bits (544), Expect = 1.636e-57 Identity = 128/332 (38.55%), Postives = 190/332 (57.23%), Query Frame = 3
Query: 1602 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCES-ENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF-------TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDS-RKSQLFGKW-----------------TEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGL 2516
RR K+ +P++S +L ++ IG++LSK+ +PV NEPLS++Q L E+ EYSD LDAAA+ +DSLE+++++AAF VS+Y++T R G KPFNP++GET+E+ R D GW+ +AEQVSHHPP + +CES + W WQEF + +KF GK + IP G + +K N W KVT+ ++NI +I+++G+M+ T +LN A F K + VTG I+ D K L G W + ++ A +W P+ + Y FT FA++LN + ++A TDSR RPDQR +E G
Sbjct: 499 RRTKI-TPRPNMS-INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTG-KPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPA-----RRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAP----TDSRLRPDQRLMETGF 818
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000065901.1 (SMESG000065901.1) HSP 1 Score: 204.142 bits (518), Expect = 5.251e-57 Identity = 127/368 (34.51%), Postives = 180/368 (48.91%), Query Frame = 3
Query: 1581 LYQEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDKGWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSS-AKITFHKSNSWVHQKFEVTGTISCPDSRKS-----QLFGKWTEGIYV-----------------------------------------GDNARC---------IWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGL 2516
+Y +TG LP P FS+ L + IG++LSK+ +P++ NEP+S LQ L E +EYS+LLD A D ++RM I AFAVS AS + R G KPFNP++GETYE RP+ +K+++EQ+ HHPPVS + ES + + K FWGKS+ P G++ + L +NE W V ++N+ +IEH G M ++ N+ A +TFH + V G I RKS +++GKWTE ++ DN C IW+ P + +Y FT F + LN + + LP TDSRFR D RY+E GL
Sbjct: 24 IYTYRTG----LPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAEIDPIKRMEKICAFAVSGGASNWGRIG-KPFNPLLGETYELHRPN--FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNMHRVDGDIYY-GQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIENDEKGDNNNNDIDDPLPQDNTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGL 383
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000008795.1 (SMESG000008795.1) HSP 1 Score: 208.764 bits (530), Expect = 5.559e-56 Identity = 144/394 (36.55%), Postives = 219/394 (55.58%), Query Frame = 3
Query: 1593 KTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITF-HKSNSWVHQKF--EVTGTISCP-DSRKSQLFGKWTEGI----------------YVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLXXXXXXXXXXXXXLQ---RIALAKVKGD----VNWKPLWF--XXXXXXXXXXXXFTNEYWSAK 2678
K RR ++P +P+I+ +L +++ IG+DLSK+ +PV +EP+S+LQ L E+ EYS +LD AA + +E+++Y+AAF VS+YA+T YR KPFNP++GETYE R D GW+ AEQ+ HHPP +CES W W +F + NKF GK I+ P G + K+ W ++ I+NI +I+++G+M+ NL + K +K S VTG I+ ++ L G W E + Y+ +++ +W+ +P + DKYY F+ FAI LN ++ D+A TDSR RPDQ+ +E G EA EK ++EE Q R+ + K+ G +KPLWF +KS++Y+F +YW K
Sbjct: 417 KRTRRTQIPP-KPNIN-MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRIN-KPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDII-NLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVQGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAP----TDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECK 802 The following BLAST results are available for this feature:
BLAST of Oxysterol-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Oxysterol-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032159 ID=SMED30032159|Name=Oxysterol-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2804bpback to top protein sequence of SMED30032159-orf-1 >SMED30032159-orf-1 ID=SMED30032159-orf-1|Name=SMED30032159-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=874bp MDTESEEESEYNFTGPWSTSQNNFNDKFNKNSKDDEKHKKPTDNPTNNSKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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