slc6a-22

Query:  131 TAYMNSNCENLDTNEDHLENSNPQR--ISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLSSQRFLEYQGFKTINATGT-------LKIGLPV-------WEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            T+ +  +   + T ED   + N  R   S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PN++   F   Q  KT  +          LKI   +       W + LC    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  167 TSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTS-QANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGP 760          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFL---------EYQGFKTINA--------------TGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI----VLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLM-KF---KGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT*INI*SIQETRIFT 1900
            + PYL +K    AF IPYT+F  I G+PLF +E+ +GQ    G    W   P  K +G  ++ + +     Y + + W+L Y F +F  NLPW+        PN +  + L         +Y  +K   A              +G   IGLP W+++LC + +  +L  +   G+    KVV+ T T+ Y  +F+L+VH ++L G+ +G+  +L I    L    +W DAA QI   L    G ++ F+S+ +   N   + L+ + ++  TS ++     +  GY+ +  K N + +  T   G+ FI  P+ IST+  + F+A V++++L+ +G D+++G +  V   + + F      ++ + T G+   +F++++     GG+Y+  L DTF+   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F+    +L+   V I+    L Y  YIF   P+  +V              GW I     LS ++ + IY++ KF   +G L +RL             Y ++P +++ L+A + +    + + Q  R  T
Sbjct:   81 RFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVA-TEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLF-TFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRP---GLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIF--PPWANWV--------------GWGIA----LSSMVLVPIYVIYKFLSTQGSLWERLA------------YGITPENEHHLVAQRDIRQFQMKTRQGRRRAT 621          

Query:  188 NSNPQRI-SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFL---------EYQGFKTINA--------------TGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI----VLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLM-KF---KGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKV 1855
            ++ P+    ++ D++L ++G+ V +  + + PYL +K    AF IPYT+F  I G+PLF +E+ +GQ    G    W   P  K +G  ++ + +     Y + + W+L Y F +F  NLPW+        PN +  + L         +Y  +K   A              +G   IGLP W+++LC + +  +L  +   G+    KVV+ T T+ Y  +F+L+VH ++L G+ +G+  +L I    L    +W DAA QI   L    G ++ F+S+ +   N   + L+ + ++  TS ++     +  GY+ +  K N + +  T   G+ FI  P+ IST+  + F+A V++++L+ +G D+++G +  V   + + F      ++ + T G+   +F++++     GG+Y+  L DTF+   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F+    +L+   V I+    L Y  YIF   P+  +V              GW I     LS ++ + IY++ KF   +G L +RL             Y ++P +++ L+A + +
Sbjct:   52 DAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVA-TEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLF-TFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRP---GLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIF--PPWANWV--------------GWGIA----LSSMVLVPIYVIYKFLSTQGSLWERLA------------YGITPENEHHLVAQRDI 606          

Query:  188 NSNPQRI-SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFL---------EYQGFKTINA--------------TGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI----VLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLM-KF---KGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKV 1855
            ++ P+    ++ D++L ++G+ V +  + + PYL +K    AF IPYT+F  I G+PLF +E+ +GQ    G    W   P  K +G  ++ + +     Y + + W+L Y F +F  NLPW+        PN +  + L         +Y  +K   A              +G   IGLP W+++LC + +  +L  +   G+    KVV+ T T+ Y  +F+L+VH ++L G+ +G+  +L I    L    +W DAA QI   L    G ++ F+S+ +   N   + L+ + ++  TS ++     +  GY+ +  K N + +  T   G+ FI  P+ IST+  + F+A V++++L+ +G D+++G +  V   + + F      ++ + T G+   +F++++     GG+Y+  L DTF+   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F+    +L+   V I+    L Y  YIF   P+  +V              GW I     LS ++ + IY++ KF   +G L +RL             Y ++P +++ L+A + +
Sbjct:   52 DAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVA-TEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLF-TFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRP---GLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIF--PPWANWV--------------GWGIA----LSSMVLVPIYVIYKFLSTQGSLWERLA------------YGITPENEHHLVAQRDI 606          

Query:  188 NSNPQRI-SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFL---------EYQGFKTINA--------------TGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEH 1612
            ++ P+    ++ D++L ++G+ V +  + + PYL +K    AF IPYT+F  I G+PLF +E+ +GQ    G    W   P  K +G  ++ + +     Y + + W+L Y F +F  NLPW+        PN +  + L         +Y  +K   A              +G   IGLP W+++LC + +  +L  +   G+    KVV+ T T+ Y  +F+L+VH ++L G+ +G+  +L I    L    +W DAA QI   L    G ++ F+S+ +   N   + L+ + ++  TS ++     +  GY+ +  K N + +  T   G+ FI  P+ IST+  + F+A V++++L+ +G D+++G +  V   + + F      ++ + T G+   +F++++     GG+Y+  L DTF+   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F       V    ++ L Y I    EH
Sbjct:   52 DAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVA-TEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLF-TFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRP---GLYWRLCWKF-------VSPAFLLRLAYGITPENEH 542          

Query:  185 ENSNPQR--ISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPE-----------AM-QTPDPNLSSQRFLE-----YQGF---KTINATGT------LKIGLPVWEIVLCSLAIWFLLCLAAIY-GIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISF--IVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
            E  +P R   S + D++L ++G+ V +G I + PYL  K     F IPY+I   + G+PLF +E+ +GQ   +G I  WG   PL K +G  ++         Y + + W L Y + +F+ NLPW        SP            AM ++ + ++S+++        Y+GF      NA  +        +G   W+I L SL + +L+C  +++ GIH   KVV+FT    YV + IL +  ++L G  +G++Y+LR     L   ++W DAA Q+   L    G +M +SS+     N+ V+ L  +F++ +TS L+     +  GY++ K             G+ F+  P+ +ST+P A F++ +++++L+T+G D++ G    +   + + F     ++E +V    C  +F  ++ I +C  GG+ +      +  +W  L       +++  +Y   +   D+  M+   P
Sbjct:   34 EPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIAL-SLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCKSGKPIEAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFPILKKNREVFVG---CLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRP 509          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP-----------------------EAMQTPDPNLSSQRFLEYQGFKTINATGTL-KIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLN--LKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS-KNNYDKEAYVTIGI-CAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTE-ISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGP---LVKRLKGLLNQNENDKPWYPVSPNDKN 1831
             +  + L+ ++ H E  +  + + +FD+++ M+ Y VG+G + + PYL +K    +F + Y IF+ +  +P+FL+EV VGQ   +G +E W   PL + +G+G V +    +  + + V WA+ Y   +     PW                         +A+       +     ++   + ++ TG + + G   WE+     A W ++  A   GI    K VYF     YV IFIL++  ++LEG+  G+ ++L+   + L + A+W DA  Q+     +  G ++   S  +   N   + + + F++  TSI A     +  GY++   +K   +I+K    +G+ F+A P+V S +P    FA ++++++  +G D+ +  +  +  ++ + F     Y K+   ++GI C   F + IP+    G +   LFD +  S   L   +   ++ L    G   I   ++ M+    +TL    +  W F         +VL +F V  +Y    HP   Y + + + + ++  A GWF+ SC  + V+    IY + F      L +R++  LN + + +     SP  KN
Sbjct:   13 EAKAKELEQSQ-HSEEPDRGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSFLVVYMIFFCLAAVPIFLMEVTVGQYLQKGAMEMWLMCPLFRGVGIGNVVIAFMCIAYFCVIVAWAMFYMISSIAWVFPWETCNNYWNDATCVTGKENFTELARIKALVASAGGHTQTSVEQFWEKRVLHDTGDISEFGGIQWELFFIMAAAWLIVYFALWKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGTGIYFYLKPNATRLLDTAVWKDAGTQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTSITAGFAVFSILGYMSHVAQKDISEIVKP--GVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDSQVCMMEGLFTALEDAFPILRKYKKQ---SLGIFCLFFFCIGIPMVTHSGSHWLTLFDAYGASGYALLFVVFFEVVGLAYGFGAHNIRKALHEMIG---VTLPKGIEYVWKFCA---PATSLVLFVFCV--VYY---HPVK-YPDGKDFPFWAN--AFGWFLSSC-SMVVIPGYAIYYLFFTNKHLTLKERVRKGLNLDGSFE-----SPAKKN 584          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFN-SNLPWS--PEAMQTPD--------PNLSSQRFLEYQGFK----------------------TINATGTLKIGLPV----------------------WEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELF---SKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNS 1390
            + PYL ++    AF IPY I     G PLF+LE   GQL S G +  +   P+ K +G+    +     I Y++ + WA  Y + +F  S++PW     A  TP+        P  S++   E+   K                      T+ +   L +  PV                      W++ L  L +W +  L    G+ +  KVVY T +  Y+ +F L++  ++LEG+  GL+++L+   S L    +W DA  Q+     L  G ++   S+ +   N+    L + FV+  TS+ A     ++ G++  ++            G+ F+A P  I  +P   F++ +++++++ +G D+    +     +I++ F    +  Y +E +V + IC IS+++ +     GG Y+F LFD ++ S
Sbjct:   35 RFPYLCYQNGGGAFLIPYCISLVFCGAPLFILETSWGQLMSVGGLGMFKICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFTMSDVPWKNCDHAWNTPNCRSEYVKIPCDSNRTIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWTVCSAADLSVVSPVKEFWNHRVLGISSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWTGKVVYITASFPYMMLFCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSYGLGLGALVALGSYNKFNNNVYKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEVAQAGPGLLFLAYPSGILQLPYTQFWSCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIRRKKYGREIFVGV-ICVISYLIGLTTVTEGGFYVFQLFDFYAAS 467          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGM------VALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLS-----------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNL---KKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNEN 1792
            + P + +K+   AF IPY I   I GLP+F +E+ +GQ    GC+  W    PL + +G G+      +A+  N +I   +Y  +A+      ++S +PW+        P  S                 S+ +  Y+  +   +TG   +G     + +C LA++ ++  A   G     K+V+ T T  Y+ + IL++  + L G+ +GL Y++      L + A+W+ AA QI   L    G ++  SS+     N   + +  + ++ +TS  +     +  GY++L   K  N  + +   +L   FI  PQ ++T+  + F++F+++++L+T+G D+    +        +     + +++ +V + IC I + +S P  + GG ++ P  D +  S + L       I +   Y   + S DI  ML   P           Y+ V W      + +IF++  +Y     P    +    Y +    +  GWF+     L++ +   IYL+   G L +R +  +   + 
Sbjct:  125 RFPSVCYKHGGGAFLIPYFIMLMIGGLPMFYMELVLGQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQAVY--FAIVSLSKIWDSEVPWASCGNPWNTPRCSDDLNVTISRNGTPLTTPSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIMVYFALWKGPQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAATQIFFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTNKPINEVVGEHDASL--IFIVYPQALATMDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDESRFLSKNRKWFVLV-ICIIYYFLSFPAISYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCWFYGVDQFSKDIRAMLGFYPGI---------YWRVCWTCSPVFISVIFIM-TVYNSSFKP----IQMASYTFPWWSVILGWFLRLLSVLAIPVFAIIYLLSGTGTLYERFRWAITPQQR 642          

Query:  185 ENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYT-AAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVI--WALRYFFLTFNSNLPWSP---------------------------------------EAMQTPDPNLSSQRFLEY-QGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGY------LNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWK 1516
            EN      S + DY+L +IG+  G+G   K P+LV ++  AAF +PY     +  LP+F +E+ +GQ +S   I  W   PL K  G+G   +T++G       +I  W L Y   +F+ ++PWS                                        E    P  +L S   L+Y Q    + + G    G   W + LC LA W  + L    G+    KVVY  + + ++ + +L+   ++L+GSL  + YFL  +   L ++ +W +AA+Q    +S   GG+   +S+ +   N+  +  ++  VD   S++ C+ + +  G+      ++L KF+   ++D  +L   F+A  + ++ +  A  +A +++I+++ +   T +  V  +  SI + + +       +V   +CA+  ++SIP C S GL+   L   F  +W  +  A L  + +  +Y    +  +  +++   P     WK
Sbjct:   60 ENRIRGNWSNKSDYLLAVIGFTAGVGSFWKFPFLVFQHGGAAFLVPYLCMLCLASLPMFFMEMVLGQFSSSAAISVWKVVPLFK--GIGFAQVTISGFFAVFFNIISAWTLFYLINSFSFSIPWSNCANSWSGENCTLGTRIQCKEMNGTLLVNGSCIVEHASSNETTVIPLHDLGSIPSLKYFQNDVLMLSKGVDDFGTLNWYLGLCVLACWIAVFLCLFQGVKSSGKVVYVAVIVPFIILTVLLTRLLTLDGSLAAVFYFLTPKWEILMDLHVWGEAAVQAFYSVSCCSGGLFTIASYSRFHNNIYKDIWLVLIVDVIVSLVGCLLTFSAIGFTCYEFAISLDKFH---IRDGFHLVFVFLA--EALAGVSVAPLYAGLFFIMILLVVHATQMFVVETIVSSICDEYPERLRRNRRHVLTTVCALFILLSIPFCLSSGLFWMELLTQFVLTWPLVVIAFLECMAINWVYGVDNMLDNAKWIVGYWPPCYIFWK 547          

Query:  272 KTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLIT--YVMYVIWALRYFFLTFNSNLPW--SPEAMQTPD-------------PNLSSQRFLEYQGFKTINATGTLKI-GLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS---KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW--YGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGS----CVPLSVLITIGIYLMKFKGPLVKRLKGLLNQN 1786
            + PY+ +K     F +PY I  FI  +PL  +E+ VGQ T RG I   G   PL K  G G+ ++ V+ L++  Y + + +++ YFF +F + +PW        TPD             P+ S     E+   K +  +G L+  G+  WE+  C +  W ++  A    I    KV YFT T  +V I IL+V +++L+G+ +GL++F R   S+L N  +W +AA Q    L +  G ++ F+S+ +   N++ +T+ ++ V+  TS+L  IF+ +  G L L++ N  + +D    G G  F+  PQ ++ +P A  +A +++ +L+ +G ++    V +V  SI + F    K +      V + +C IS +  +P    GG+Y F L D ++ S T +  A    I +   Y    +S ++  M    P          +Y    W   GP     ++F ++ + +   H  T++  +  Y Y       GW   S    C+P   +I    +L        +R++  L  N
Sbjct:   77 RFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFK--GAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQ-NTNV-RDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP---------SFYLRSCWLVLGPC----LLFAIWVLSLINYHEPTYH--NGRYTYPDWAYGIGWMFASFSLICIPGYAVIN---FLRSSGDTFWERIRNTLRPN 592          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW----------------SPEAMQTP------------------------DPNLSSQRFLEYQGFKTI-------------NATGTLKIGLPVWEIVLCSLAIWFLLCLAAIY-GIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFI-GSCVPLSVLITIGIYLMKFKGPLVKR 1762
             S       N+++  +   +  S + D++L +IG+ V +  + + PYL +K    AF +PY I   + G+PLF +E+ +GQ   +G I CWG   PL K +G  +V +       Y + + W+LR+FF +F ++LPW                S  A + P                          +L +      +GF++               + G   +G   W++ LC L I +L+C  +++ GI    KVV+FT    Y  + IL++  ++L GS  G++Y+L    S +    +W DAA Q+   L    G ++ ++S+ +   N+  + L+ +F++ +TS +A     +  GY+       +I +D    G G  F+  P  I+T+P + F+A +++++L+T+G D++ G    +  ++ + F K   ++E +V  G+ ++ F+V +  C  GG Y F L D ++  ++ L       I +  +Y     S DI  M+   P   + W ++ W F+        I L+   VY   + G  P T+      Y Y S   A GW I GS V +   + I   L+   G L +R
Sbjct:    9 KSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALC-LLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYM-AHTLGVRI-EDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVA-GLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPP--GRYW-QVCWRFV------APIFLLFITVYG--LIGYEPLTY----ADYVYPSWANALGWCIAGSSVVMIPAVAI-FKLLSTPGSLRQR 589          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW----------------SPEAMQTP------------------------DPNLSSQRFLEYQGFKTI-------------NATGTLKIGLPVWEIVLCSLAIWFLLCLAAIY-GIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFI-GSCVPLSVLITIGIYLMKFKGPLVKR 1762
             S       N+++  +   +  S + D++L +IG+ V +  + + PYL +K    AF +PY I   + G+PLF +E+ +GQ   +G I CWG   PL K +G  +V +       Y + + W+LR+FF +F ++LPW                S  A + P                          +L +      +GF++               + G   +G   W++ LC L I +L+C  +++ GI    KVV+FT    Y  + IL++  ++L GS  G++Y+L    S +    +W DAA Q+   L    G ++ ++S+ +   N+  + L+ +F++ +TS +A     +  GY+       +I +D    G G  F+  P  I+T+P + F+A +++++L+T+G D++ G    +  ++ + F K   ++E +V  G+ ++ F+V +  C  GG Y F L D ++  ++ L       I +  +Y     S DI  M+   P   + W ++ W F+        I L+   VY   + G  P T+      Y Y S   A GW I GS V +   + I   L+   G L +R
Sbjct:    9 KSKTPTPHDNDNNSISDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALC-LLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYM-AHTLGVRI-EDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVA-GLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPP--GRYW-QVCWRFV------APIFLLFITVYG--LIGYEPLTY----ADYVYPSWANALGWCIAGSSVVMIPAVAI-FKLLSTPGSLRQR 589          

Query:  278 PYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLIT--YVMYVIWALRYFFLTFNSNLPW--SPEAMQTPD-------------PNLSSQRFLEYQGFKTINATGTLK-IGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS---KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW--YGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGS----CVPLSVLITIGIYLMKFKGPLVKRLKGLLNQN 1786
            PY+ +K     F +PY I  FI  +PL  +E+ VGQ T RG I   G   PL K  G G+ ++ V+ L++  Y + + +++ YFF +F + +PW        TPD             P+ S     E+   K +  +G L+  G+  WE+  C +  W ++  A    I    KV YFT T  +V I IL+V +++L+G+ +GL++F R   S+L N  +W +AA Q    L +  G ++ F+S+ +   N++ +T+ ++ V+  TS+L  IF+ +  G L L++ N  + +D    G G  F+  PQ ++ +P A  +A +++ +L+ +G ++    V +V  SI + F    K +      V + +C IS +  +P    GG+Y F L D ++ S T +  A    I +   Y    +S ++  M    P          +Y    W   GP     ++F ++ + +   H  T++  +  Y Y       GW   S    C+P   +I    +L        +R++  L  N
Sbjct:  364 PYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFK--GAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQ-NTNV-RDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP---------SFYLRSCWLVLGPC----LLFAIWVLSLINYHEPTYH--NGRYTYPDWAYGIGWMFASFSLICIPGYAVIN---FLRSSGDTFWERIRNTLRPN 877          

Query:  278 PYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLIT--YVMYVIWALRYFFLTFNSNLPW--SPEAMQTPD-------------PNLSSQRFLEYQGFKTINATGTLK-IGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS---KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW--YGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGS----CVPLSVLITIGIYLMKFKGPLVKRLKGLLNQN 1786
            PY+ +K     F +PY I  FI  +PL  +E+ VGQ T RG I   G   PL K  G G+ ++ V+ L++  Y + + +++ YFF +F + +PW        TPD             P+ S     E+   K +  +G L+  G+  WE+  C +  W ++  A    I    KV YFT T  +V I IL+V +++L+G+ +GL++F R   S+L N  +W +AA Q    L +  G ++ F+S+ +   N++ +T+ ++ V+  TS+L  IF+ +  G L L++ N  + +D    G G  F+  PQ ++ +P A  +A +++ +L+ +G ++    V +V  SI + F    K +      V + +C IS +  +P    GG+Y F L D ++ S T +  A    I +   Y    +S ++  M    P          +Y    W   GP     ++F ++ + +   H  T++  +  Y Y       GW   S    C+P   +I    +L        +R++  L  N
Sbjct:  364 PYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFK--GAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQ-NTNV-RDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP---------SFYLRSCWLVLGPC----LLFAIWVLSLINYHEPTYH--NGRYTYPDWAYGIGWMFASFSLICIPGYAVIN---FLRSSGDTFWERIRNTLRPN 877          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLS----------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQI-LKDTTNLG--VGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            +   E++  N+   ENS+    S + +Y+L MIGY VG+G + + PYL +K+   AF IPYTI   + GLPLF +E   GQ  S+G I  W   P+L+ +G+ M+ ++    I Y + + +++ Y F +F   LPWS +   T   N+S                S+++ +    +   ++   + G  VW + LC L  W L+  A   GI    KVVYFT T  Y+ + IL++   +LEG+ DG+++++     ++ L    +W DAA QI   LS+A GG+M  SS+ +   N   +++++   +  TSI A     A F  L      +Q  + +  + G  + FIA P  +S +P +  ++ +++ +L+T+G D+    + ++S  +L+ + +    K   VT  +C I F++ +P     G+Y   L DTFS  W  L   LL  + + +LY G     DI  M+        +W +  W+FI        +VL I L++ +Y F    ++         Y    ++ GW I +   + + I     + K +G L +R+K   +  E+  P+      ++
Sbjct:   27 SDKAEHVVQND---ENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWSIKNCNTTASNISTAAVNVSCGQISGQSLSEKYWDEVALQ--RSSSMDETGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGF---AIFSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFI------TPVVLSIILIWSLYTFTSPTYSSVA------YPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGPYLECHRGER 592          

Query:  272 KTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQ--------TPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS--KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIW-KKIKWYFIVLWYGPVQIVLMIFLVYKI--YIFGE-HPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLK 1768
            + PYL ++     F IPY I  F  G+PLFL+E+ +GQ  + G I  W C PLLK +G+GM+ ++    + Y + + W   Y   +F S LPWS +A+Q        T      S+ F   +    +++TG    G   W + LC LA W ++ L  + GIH   KVVY T T  Y  + +LI+   +LEGSLDG+ ++L  +   L +  +W DAA QI   L +  GG++  +S+ +   N++ +T+IIT  + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L  +G DT  G +  +  ++L+ F   ++N   +      +C   +++ + L   GG+Y F L D+FS S+  +   L + I +   Y   +   DI  M+   P     W  K+  YF   W     +V   FL+  I  YIF E +  +    S VY      L  G  +G+   L +LI   + + K  G L  R K
Sbjct:   96 RFPYLCYRNGGGVFLIPYFIMLFFTGMPLFLMELSLGQYGAAGPITVWKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSSFQSPLPWSCDALQNIALCANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRWPLALCLLAAWIIIFLCMLKGIHSSGKVVYVTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKWDQLADAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSFFAGFAIFSILGHMAFKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFMLGVDTLFGNMEGICTAVLDEFPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLIDSFSTSFGLIIITLFMCIGISFFYGVNQFCQDIVDMICRCP----PWCTKMLLYFKACW-----VVFTPFLLTFILTYIFIEMYRTSLRYGSYVYPIWGKAL--GVCMGALCCLQILIWAIVAISKESGTLKDRFK 600          

Query:   74 FNANPKET-----RQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQTPD---------------PNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI 1537
            FN   KE      +++N + Y  N++ + S      T+    E    +   ++ D++L +IG+ V +  + + PYL +K    AF IPY +F FI G+PLF +E+ +GQ    G    W   P+ K +G  ++ + +     Y + + W+L Y + +  S LPW        SP   +  D                N  +  F E     +  + G   +GLP WE+ +C + + F+L  +   G+    KVVY T T+ Y+ + +L++  I+L G+++G++ +L I    L N  +W DAA QI   L    G ++ FSS+ +   N   + ++ + ++  TS  +     +  GY+    K N   +KD    G G  F+  P+ IST+P A FFA V++I+L+T+G D+++G +  V   + + F     +++ + T      +F++++    +GG+Y+  L D ++   + L   L   I +   Y     S DI  M+   P    I+ ++ W F+
Sbjct:   20 FNVEKKEVELILVKEQNGVQY-TNSSVVASPSSRACTSASG-EEIERETWGKKMDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYVLFLFIAGMPLFYMELALGQYNREGAATLWKICPVFKGVGYTVIVIALYVGFYYNVIIAWSLYYLYASLTSELPWLHCNNPWNSPNCTEPKDINGTVLGNGTSYAKYKNTPAAEFYERGVLHSHESKGIGDLGLPRWELTICLVVVAFILYFSLWKGVKSSGKVVYITATMPYIVLLVLLIRGITLPGAMNGIRAYLHIDLKKLNNPQVWIDAATQIFFSLGAGFGVLIAFSSYNKFNNNCYRDAILTSTINCVTSFFSGFAIFSVLGYMAEQHKVN---IKDVATEGAGLVFVIYPEAISTLPGATFFAIVFFIMLLTLGIDSSMGGMEAVLTGLSDDFKILKRNRKLF-TFATVVGTFLMALLCVTNGGIYVLTLLDKYAAGTSILFGVLFEAIGVSWFYGVDRFSEDIERMMGFKP---GIYWRLCWKFV 532          

Query:   74 FNANPKET-----RQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQTPD---------------PNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI 1537
            FN   KE      +++N + Y  N++ + S      T+    E    +   ++ D++L +IG+ V +  + + PYL +K    AF IPY +F FI G+PLF +E+ +GQ    G    W   P+ K +G  ++ + +     Y + + W+L Y + +  S LPW        SP   +  D                N  +  F E     +  + G   +GLP WE+ +C + + F+L  +   G+    KVVY T T+ Y+ + +L++  I+L G+++G++ +L I    L N  +W DAA QI   L    G ++ FSS+ +   N   + ++ + ++  TS  +     +  GY+    K N   +KD    G G  F+  P+ IST+P A FFA V++I+L+T+G D+++G +  V   + + F     +++ + T      +F++++    +GG+Y+  L D ++   + L   L   I +   Y     S DI  M+   P    I+ ++ W F+
Sbjct:   20 FNVEKKEVELILVKEQNGVQY-TNSSVVASPSSRACTSASG-EEIERETWGKKMDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYVLFLFIAGMPLFYMELALGQYNREGAATLWKICPVFKGVGYTVIVIALYVGFYYNVIIAWSLYYLYASLTSELPWLHCNNPWNSPNCTEPKDINGTVLGNGTSYAKYKNTPAAEFYERGVLHSHESKGIGDLGLPRWELTICLVVVAFILYFSLWKGVKSSGKVVYITATMPYIVLLVLLIRGITLPGAMNGIRAYLHIDLKKLNNPQVWIDAATQIFFSLGAGFGVLIAFSSYNKFNNNCYRDAILTSTINCVTSFFSGFAIFSVLGYMAEQHKVN---IKDVATEGAGLVFVIYPEAISTLPGATFFAIVFFIMLLTLGIDSSMGGMEAVLTGLSDDFKILKRNRKLF-TFATVVGTFLMALLCVTNGGIYVLTLLDKYAAGTSILFGVLFEAIGVSWFYGVDRFSEDIERMMGFKP---GIYWRLCWKFV 532          

Query:   68 PCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQR--ISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP-----------EAMQTPD-----------PNLSSQRF-------LEYQGFKTIN-ATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILK-DTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKN---NYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNS-WTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLM----KFKGPLVKRLKGL 1774
            P  NA+P       +++  +N   M++    +   E   E   P+R   +++ D+I+  +G+ VG+G + + PYL +K     F IPY +F F+ G+P+F LE+ +GQ    G I  W  +PL K LG   + +       Y+M + W   YF  +FN+ LPWS            E  +  D            NL+ +         +E+   K +N + G  + G   WE++LC LA+W ++      G+    K+VYFT T  YV + IL+V  ++L G+ DG+ Y+++   S LG   +W DA  QI    ++  G +    S+ +   +   +  ++  ++  TS  A     +  G++  ++    I K   +  G+ FIA P+ +S +P A  +A +++I+L+ +G D+    V      IL+LF       Y +E  V I  C + FI+ + +   GG+Y+F LFD +S S  T L  A    +++  +Y       DI  M+   P     W K  W  I     P  + + IFL    ++    P T Y N  VY +       G  IG C+ LS ++ I + L+      KG   +R + L
Sbjct:    9 PNGNAHP-------SVNGTLNGGPMSAATGAISAVEKKREGY-PERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLFIFLGGIPIFFLEIALGQFMKAGSINVWNIAPLFKGLGYASMVIVFFCNTYYIMVLAWGFYYFIKSFNATLPWSTCDNPWNTENCIEIFRQGDCKNGTIGNSTFGNLTCEELANGRSPIIEFWENKVLNISDGLDEPGAVNWELMLCLLAVWVMVYFCVWKGVKSTGKIVYFTATFPYVVLIILLVRGVTLPGAYDGILYYVKPDWSKLGEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFVLALINSGTSFFAGFVVFSILGFMASEQ-GVDISKVAESGPGLAFIAYPKAVSMMPVAPVWAALFFIMLLLLGLDSQFVGVEGFVTGILDLFPGKYYMRYQREIAVAI-CCLLCFIIDLSMVTQGGMYVFQLFDYYSASGMTLLWQAFWECVVVAWVYGADRFMDDIARMIGYRPFP---WMKWCWSIIT----PC-VCMGIFL---FHLLNYKPLT-YNNVYVYPWW------GEVIGWCLALSSMLCIPVSLVYKLSGAKGTFKERWENL 593          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAM------QTPDPNLS----SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSIL-ELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            + PYL ++    AF IPY+I  F  GLPLFL+E+ +GQ  + G I  W C P+LK +G+GM+ ++    + Y + + W   Y   +F S LPWS ++       Q    N S    ++ F   +     +++G    G   WE+ LC LA WF++ L  + GIH   K+VYFT T  Y  + +LI+   +LEGS+DG++++L      L +  +W DAA QI   L +  GG++  +S+ +   N++ +TL+I   + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L T+G DT  G +  ++ +IL E+ S  ++ ++      +C   +++ + L   GG+Y F L D++S S+  +  AL + + +   Y   +   DI  M+S  P       K+ WYF   W
Sbjct:   35 RFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGIGMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLCQNGTSNGSQFSATEAFWNEKVLGVTHSSGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYFVMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNNNVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGVPVGQVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDWKRKTIFLGCLCFAFYLLGLLLITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWC---TKVLWYFKACW 470          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAM------QTPDPNLS----SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSIL-ELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            + PYL ++    AF IPY+I  F  GLPLFL+E+ +GQ  + G I  W C P+LK +G+GM+ ++    + Y + + W   Y   +F S LPWS ++       Q    N S    ++ F   +     +++G    G   WE+ LC LA WF++ L  + GIH   K+VYFT T  Y  + +LI+   +LEGS+DG++++L      L +  +W DAA QI   L +  GG++  +S+ +   N++ +TL+I   + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L T+G DT  G +  ++ +IL E+ S  ++ ++      +C   +++ + L   GG+Y F L D++S S+  +  AL + + +   Y   +   DI  M+S  P       K+ WYF   W
Sbjct:   95 RFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGIGMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLCQNGTSNGSQFSATEAFWNEKVLGVTHSSGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYFVMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNNNVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGVPVGQVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDWKRKTIFLGCLCFAFYLLGLLLITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWC---TKVLWYFKACW 530          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEA-----MQTPDPN----------LSSQRFLEYQ--GFKTINATGTLKIGLP---VWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSIL-ELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            + PYL ++    AF IPY+I  F  GLPLFL+E+ +GQ  + G I  W C P+LK +G+GM+ ++    + Y + + W   Y   +F S LPWS ++     +    PN             +R  + Q  G K +  T +  +G P    WE+ LC LA WF++ L  + GIH   K+VYFT T  Y  + +LI+   +LEGS+DG++++L      L +  +W DAA QI   L +  GG++  +S+ +   N++ +TL+I   + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L T+G DT  G +  ++ +IL E+ S  ++ ++      +C   +++ + L   GG+Y F L D++S S+  +  AL + + +   Y   +   DI  M+S  P       K+ WYF   W
Sbjct:   74 RFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGIGMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLCQVRPNCPGGGGGYYPTGRERGSDSQCIGEKVLGVTHSSGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYFVMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNNNVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGVPVGQVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDWKRKTIFLGCLCFAFYLLGLLLITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWC---TKVLWYFKACW 519          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEA-----MQTPDPNLS-----------------SQRFLEYQGFKTINATGTLKIGLPV---WEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSIL-ELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            + PYL ++    AF IPY+I  F  GLPLFL+E+ +GQ  + G I  W C P+LK +G+GM+ ++    + Y + + W   Y   +F S LPWS ++     +    PN                    Q     +  K +  T +  +G P    WE+ LC LA WF++ L  + GIH   K+VYFT T  Y  + +LI+   +LEGS+DG++++L      L +  +W DAA QI   L +  GG++  +S+ +   N++ +TL+I   + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L T+G DT  G +  ++ +IL E+ S  ++ ++      +C   +++ + L   GG+Y F L D++S S+  +  AL + + +   Y   +   DI  M+S  P       K+ WYF   W
Sbjct:   59 RFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGIGMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLCQVRPNCPGGGGGYYPTVLYKTSQMPQAVSLCRSEKVLGVTHSSGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYFVMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNNNVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGVPVGQVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDWKRKTIFLGCLCFAFYLLGLLLITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWC---TKVLWYFKACW 509          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEA-----MQTPDPNLS----------SQRFLEYQ--GF-----------KTINATGTLKIGLPV---WEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSIL-ELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            + PYL ++    AF IPY+I  F  GLPLFL+E+ +GQ  + G I  W C P+LK +G+GM+ ++    + Y + + W   Y   +F S LPWS ++     +    PN             +R  + Q  G+           K +  T +  +G P    WE+ LC LA WF++ L  + GIH   K+VYFT T  Y  + +LI+   +LEGS+DG++++L      L +  +W DAA QI   L +  GG++  +S+ +   N++ +TL+I   + STS  A     +  G++  KK         +  G+ F+A P+ ++ +P + F++ +++++L T+G DT  G +  ++ +IL E+ S  ++ ++      +C   +++ + L   GG+Y F L D++S S+  +  AL + + +   Y   +   DI  M+S  P       K+ WYF   W
Sbjct:   83 RFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGIGMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLCQVRPNCPGGGGGYYPTGRERGSDSQCIGYIYCPCKLPSDEKVLGVTHSSGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYFVMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNNNVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGVPVGQVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDWKRKTIFLGCLCFAFYLLGLLLITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWC---TKVLWYFKACW 539          

Query:  161 LDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLS---------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            +  +E   EN      S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PNL+               S+ + +Y   K   + G    G   W +  C    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  173 IPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKI--SAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGP 754          

Query:  161 LDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLS---------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            +  +E   EN      S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PNL+               S+ + +Y   K   + G    G   W +  C    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  173 IPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKI--SAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGP 754          

Query:  161 LDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLS---------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            +  +E   EN      S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PNL+               S+ + +Y   K   + G    G   W +  C    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  173 IPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKI--SAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGP 754          

Query:   35 MNELDCDI-----VINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQTPDPNLS-------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
            M++  C +     V+ P    N    R+   I  +       +N   ++  +  +E    +  S++ D++L +IG+ V +  + + PYL +K    AF +PY +F  I G+PLF +E+ +GQ    G    W   P+LK +G  ++ ++      Y + + WAL YFF +F  +LPW        SP        N S             +  + E        + G   +G P W++  C + +  LL  +   G+    KVV+ T T+ YV +  L++  ++L G++DG++ +L +    L   ++W DAA Q+   L +  G ++ FSS+ +   N   + +I T ++  TS  +     ++ GY+  +K N  I +D    G G  FI  P+ I+T+P ++ +A V++++L+T+G D+A+G +  V   +++ F   +  +E + T+GI   +F++S+    +GG+Y+F L D F+   + L   L+  I +   Y   + S DI  M    P
Sbjct:    1 MSKSKCSVGPMSSVVAPAKEPNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEVQERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHSSNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSGFVVFSFLGYMA-QKHNVPI-RDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELF-TLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRP 515          

Query:   62 INPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRI-SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFL---------EYQGFKTINA--------------TGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYL----MKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKV 1855
            + PC  A+    ++ N +             + L  ++D   ++ P+    ++ D++L ++G+ V +  + + PYL +K    AF IPYT+F  I G+PLF +E+ +GQ    G    W   P  K +G  ++ + +     Y + + W+L Y F +F  NLPW+        PN +  + L         +Y  +K   A              +G   IGLP W+++LC + +  +L  +   G+    KVV+ T T+ Y  +F+L+VH ++L G+ +G+  +L I    L    +W DAA QI   L    G ++ F+S+ +   N   + L+ + ++  TS ++     +  GY+ +  K N + +  T   G+ FI  P+ IST+  + F+A +++++L+ +G D+++G +  V   + + F      ++ +  + +   +F++++     GG+Y+  L DTF+   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F       V    ++F+V  + I    P T+       +YT    A   ++G  + LS +I +  Y+    +  +G L +R+             Y ++P +++ L+A + V
Sbjct:   25 LRPCKTADLLVVKERNGV-------------QCLLASQD--SDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVA-TEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCV-VTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKP---GLYWRLCWKF-------VSPAFLLFVVV-VSIINFKPLTY------DDYTYPPWAN--WVGWGIALSSMILVPAYVIYKFLSIRGSLWERVA------------YGITPENEHHLVAQRDV 606          

Query:  131 TAYMNSNCENLDTNEDHLENSNPQR--ISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLSSQRFLEYQGFKTINATGT-------LKIGLPV-------WEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            T+ +  +   + T ED   + N  R   S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PN++   F   Q  KT  +          LKI   +       W + LC    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  167 TSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTS-QANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGP 760          

Query:  158 NLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLS---------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
             +  +E   EN      S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PNL+               S+ + +Y   K   + G    G   W +  C    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  180 TIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKI--SAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGP 762          

Query:  161 LDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLV-HKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQ--------------------------TPDPNLS---------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            +  +E   EN      S + D+IL M+GY VG+G + + PYL       AF IPY +   + GLP+F LEV +GQ  S+G +  W   P L+  G+ M+ ++V   I Y + + + L Y F +F S LPW        +PE                             T  PNL+               S+ + +Y   K   + G    G   W +  C    W ++  +   GI    KVVYFT T  YV + IL++  ++L G+  G+ YF+  +   L +  +W DAA QI   LS A GG++  SS+ +   N   +TLI+T  + +TSI A     +  G++ N +K N + + D    G+ F+  P+ ++ +P + F+A +++++L+T+G DT    +  +  SI + F K     +   T+G C   FI+  P+   GG+Y+F L DT++ S+  +  A+   + +  +Y       DI  M+   P    I+ K+ W F+         +L   L +  Y +   P T+      Y Y +  +  GW + +C  + + I   I +    G  ++RLK + +   +  P
Sbjct:  181 IPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKI--SAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQ-GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKP---NIFWKVCWAFV------TPTILTFILCFSFYQW--EPMTY----GSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGP 762          

Query:   35 MNELDCDI-----VINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQTPDPNLS-------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
            M++  C +     V+ P   +N    R+   I  +       +N   ++  +  +E    +  S++ D++L +IG+ V +  + + PYL +K    AF +PY +F  I G+PLF +E+ +GQ    G    W   P+LK +G  ++ ++      Y + + WAL YFF +F  +LPW        SP        N S             +  + E        + G   +G P W++  C + +  LL  +   G+    KVV+ T T+ YV +  L++  ++L G++DG++ +L +    L   ++W DAA Q+   L +  G ++ FSS+ +   N   + +I T ++  TS  +     ++ GY+  +K N  I +D    G G  FI  P+ I+T+P ++ +A V++++L+T+G D+A+G +  V   +++ F   +  +E + T+GI   +F++S+    +GG+Y+F L D F+   + L   L+  I +   Y   + S DI  M    P
Sbjct:    1 MSKSKCSVGPMSSVVAPAKESNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEAQERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSGFVVFSFLGYMA-QKHNVPI-RDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELF-TLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRP 515          

Query:   35 MNELDCDI-----VINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--------SPEAMQTPDPNLS-------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
            M++  C +     V+ P    N    R+   I  +       +N   ++  +  +E    +  S++ D++L +IG+ V +  + + PYL +K    AF +PY +F  I G+PLF +E+ +GQ    G    W   P+LK +G  ++ ++      Y + + WAL YFF +F  +LPW        SP        N S             +  + E        + G   +G P W++  C + +  LL  +   G+    KVV+ T T+ YV +  L++  ++L G++DG++ +L +    L   ++W DAA Q+   L +  G ++ FSS+ +   N   + +I T ++  TS  +     ++ GY+  +K N  I +D    G G  FI  P+ I+T+P ++ +A V++++L+T+G D+A+G +  V   +++ F   +  +E + T+GI   +F++S+    +GG+Y+F L D F+   + L   L+  I +   Y   + S DI  M    P
Sbjct:    1 MSKSKCSVGPMSSVVAPAKEPNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEVQERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHSSNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSGFVVFSFLGYMA-QKHNVPI-RDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELF-TLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRP 515          

Query:   35 MNELDCDIVINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT 1858
            MNELDCDIVINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYILIMIGYIVGIGGIIKTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT
Sbjct:    1 MNELDCDIVINPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYILIMIGYIVGIGGIIKTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT 608          

Query:  173 EDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP--------------------EAMQTPDPNL-------SSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLN--LKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMI---FLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLI---TIGIY-LMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            +D  EN+     + + +YIL  IGY VG+G I + PYL +K    AF IPY +   + G+PLF LE   GQ  S+G I  W   PLL+ +GV MV +T+   I Y + + ++L Y F +F S LPWS                     E    P  ++        S+++ +    +   ++G  + G  VW + LC L    L+  A I GI    KVVYFT T  YV IFIL++  ++LEG+ DG+++++     ++ L    +W DAA Q    LS+  GG+M  +S+     N+  ++ ++T  +  TS+ A     +  G++    K    Q++K+    G+ FIA P  +S +P +  ++ +++ +L+T+G D+    + +++  +L+ F      K A +TI  CAI +++ +P  +  G+Y   L D F  SW  L  ALL  I +  +Y G     DI  ML N   T  +W +  W+FI     P  IV+++    + +K   +GE  F  +            LA GW    C+ + +L     I +Y LM+ KG   KRLK L + +E   P+  V   D+
Sbjct:   27 DDGDENTERGNWASKREYILSTIGYAVGLGNIWRFPYLAYKNGGGAFLIPYFVMLVVTGIPLFFLESAFGQFCSQGPINIWRAVPLLQGVGVAMVTVTLIVSIYYNVIIAYSLYYMFASFQSPLPWSSCFSWADSNCSTTPIVANWTQENSTCPSSDVITVPVQSPSEQYWDRVALQ--RSSGLDETGPIVWHLALCLLLSSILVAGALIRGIKSSGKVVYFTATFPYVVIFILLIRGVTLEGARDGIEFYIGSQSNLTKLSEAQVWKDAATQTFYSLSIGWGGVMTLASYNNFHNNVFKDSFVVTLTNAGTSVFAGFAIFSILGHMAHIYKMPVGQVVKE--GFGLAFIAYPDALSKLPISPLWSILFFFMLLTVGLDSQFAGIEVITTCLLDAFPNIFKSKRALLTITTCAILYLLGLPCVSQAGIYWVTLIDQFVASWVLLVLALLEIIGVCYIYGGNRFIKDIEMMLGNKTSTFWLWWRACWFFI----SPCIIVVILVWSLMTFKPPTYGEVQFPVW-----------GLALGW----CMVVFILFWIPAIAVYKLMRAKGSPWKRLKSLCSPSEKWHPYLDVHRGDR 596          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP-----------------------------EAMQTPDPNL-------SSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLN--LKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIF--LVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLI---TIGIY-LMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            + PYL +K    AF IPY +   + G+PLF LE   GQ  S+G I  W   PLL+ +GV MV +T+   I Y + + ++L Y F +F S LPWS                              E    P  ++        S+++ +    +   ++G  + G  VW + LC L    L+  A I GI    KVVYFT T  YV IFIL++  ++LEG+ DG+++++     ++ L    +W DAA Q    LS+  GG+M  +S+     N+  ++ ++T  +  TS+ A     +  G++    K    Q++K+    G+ FIA P  +S +P +  ++ +++ +L+T+G D+    + +++  +L+ F      K A +TI  CAI +++ +P  +  G+Y   L D F  SW  L  ALL  I +  +Y G     DI  ML N   T  +W +  W+FI     P  IV++++  + +K   +GE  F  +            LA GW    C+ + +L     I +Y LM+ KG   KRLK L + +E   P+  V   D+
Sbjct:   28 RFPYLAYKNGGGAFLIPYFVMLVVTGIPLFFLESAFGQFCSQGPINIWRAVPLLQGVGVAMVTVTLIVSIYYNVIIAYSLYYMFASFQSPLPWSSCFSWADSNCSTTPIVSCNVSGVVVANWTQENSTCPSSDVITVPVQSPSEQYWDRVALQ--RSSGLDETGPIVWHLALCLLLSSILVAGALIRGIKSSGKVVYFTATFPYVVIFILLIRGVTLEGARDGIEFYIGSQSNLTKLSEAQVWKDAATQTFYSLSIGWGGVMTLASYNNFHNNVFKDSFVVTLTNAGTSVFAGFAIFSILGHMAHIYKMPVGQVVKE--GFGLAFIAYPDALSKLPISPLWSILFFFMLLTVGLDSQFAGIEVITTCLLDAFPNIFKSKRALLTITTCAILYLLGLPCVSQAGIYWVTLIDQFVASWVLLVLALLEIIGVCYIYGGNRFIKDIEMMLGNKTSTFWLWWRACWFFI----SPCIIVILVWSLMTFKPPTYGEVQFPVW-----------GLALGW----CMVVFILFWIPAIAVYKLMRAKGSPWKRLKSLCSPSEKWHPYLDVHRGDR 572          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLS----------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQI-LKDTTNLG--VGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            +   E++  N+   ENS+    S + +Y+L MIGY VG+G + + PYL +K+   AF IPYTI   + GLPLF +E   GQ  S+G I  W   P+L+ +G+ M+ ++    I Y + + +++ Y F +F   LPWS +   T   N+S                S+++ +    +   ++   + G  VW + LC L  W L+  A   GI    KVVYFT T  Y+ + IL++   +LEG+ DG+++++     ++ L    +W DAA QI   LS+A GG+M  SS+ +   N   +++++   +  TSI A     A F  L      +Q  + +  + G  + FIA P  +S +P +  ++ +++ +L+T+G D+    + ++S  +L+ + +    K   VT  +C I F++ +P     G+Y   L DTFS  W  L   LL  + + +LY G     DI  M+        +W +  W+FI        +VL I L++ +Y F    ++         Y    ++ GW I +   + + I     + K +G L +R+K   +  E+  P+      ++
Sbjct:   27 SDKAEHVVQND---ENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWSIKNCNTTASNISTAAVNVSCGQISGQSLSEKYWDEVALQ--RSSSMDETGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGF---AIFSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFI------TPVVLSIILIWSLYTFTSPTYSSVA------YPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGPYLECHRGER 592          

Query:  143 NSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLS----------------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQI-LKDTTNLG--VGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            +   E++  N+   ENS+    S + +Y+L MIGY VG+G + + PYL +K+   AF IPYTI   + GLPLF +E   GQ  S+G I  W   P+L+ +G+ M+ ++    I Y + + +++ Y F +F   LPWS +   T   N+S                S+++ +    +   ++   + G  VW + LC L  W L+  A   GI    KVVYFT T  Y+ + IL++   +LEG+ DG+++++     ++ L    +W DAA QI   LS+A GG+M  SS+ +   N   +++++   +  TSI A     A F  L      +Q  + +  + G  + FIA P  +S +P +  ++ +++ +L+T+G D+    + ++S  +L+ + +    K   VT  +C I F++ +P     G+Y   L DTFS  W  L   LL  + + +LY G     DI  M+        +W +  W+FI        +VL I L++ +Y F    ++         Y    ++ GW I +   + + I     + K +G L +R+K   +  E+  P+      ++
Sbjct:   38 SDKAEHVVQND---ENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWSIKNCNTTASNISTAAVNVSCGQISGQSLSEKYWDEVALQ--RSSSMDETGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGF---AIFSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFI------TPVVLSIILIWSLYTFTSPTYSSVA------YPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGPYLECHRGER 603          

Query:   83 NPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWS------------------------------------------PEAM--QTPDPNLSSQRF--LEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKP 1801
            NP  + +  N         + S   ++ T +++ E  N    S + +Y+L MIGY VG+G + + PYL +K+   AF IPY I   I GLPLF LE   GQ  S+G I  W   P+L+ +G+ M+ ++    I Y + + +++ Y F +F   LPWS                                          PE +   TP   +S Q +  +  Q   +++ TG +     VW + LC L  W ++  A   GI    KVVYFT T  Y  + IL++  ++LEG+ +G++Y++     ++ L    +W DAA QI   LS+A GG+   +S+ +   N   +++I+   +  TSI A     +  G++                G+ FIA P  +S +P +  ++ +++ +L+T+G D+    + +++  + + + K    K   +T+ IC + F++ +P     G+Y   L DTF   W  L   LL    +  +Y G     DI  M+ N      IW +  W+FI         VL++ L + +Y F    +          Y    +A GW + +   + + I     + K  G L +R+K      E+  P
Sbjct:   16 NPTASDEAKNA--------VKSQDPHVGTEDENAERGN---WSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYVIMLSIAGLPLFFLESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVILAYSIYYLFASFQYPLPWSNCSGWSDMGCNINATEYCNTTSYNGSLVALNRSAGADGNQSCPEELIVSTPLQTISEQYWDVVALQRTSSMDETGPV-----VWHLALCLLLGWIMIGAALFKGIKSSGKVVYFTATFPYAVLLILLIRGVTLEGARNGIEYYIGSQSNLTKLSEAEVWKDAATQIFFSLSIAWGGLTALASYNKFHNNCYKDSIIVCVTNCGTSIFAGFAIFSILGHMAHVYGKPVSEVAQAGFGLAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVITTCLQDAYPKFLKSKRGLITVIICVVLFLLGLPCVTGAGIYWVNLIDTFVAGWILLVAGLLEVFGLSCIYGGNRFIKDIEMMIGNKSAIFWIWWRSCWFFI------TPFVLLVILGWSVYTFTAPTY------GTVEYPEWGIALGWCMTAFCLMWIPIVAVWRIAKASGGLWQRIKSTCVPTEDWGP 611          

Query:  272 KTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTP-------DPNLS-SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS--KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIW-KKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLK 1768
            + PYL ++     F IPY I  F  G+PLFL+E+ +GQ  + G I  W C PLLK +G+GM+ ++    + Y + + W   Y   +F S LPWS +A+          +  LS S+ F   +     ++TG    G   W++ LC LA W ++ L  + GI    KVVY T T  Y+ + +LI+   +LEGSL G+ ++L      L N  +W DAA QI   L +  GG++  +S+ +   N++ +TL+IT  + +TS  A     +  G++  +K         +  G+ F+A P+ ++ +P + F+A +++++L  +G DT  G +  ++ ++L+ F   ++N   +      +C   +++ + L  +GG+Y F L D+ S S+  +   L + + +   Y   +   DI  M+   P     W  K+  YF   W      +L+  L Y        P  +      Y Y     A G  +G+   L +LI   + + K  G L  R +
Sbjct:  104 RFPYLCYRNGGGVFLIPYFIMLFFTGMPLFLMELSLGQYGAAGPITVWKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSSFQSPLPWSCDAIANAKLCRNNTNGTLSPSEFFWNERVLGVSHSTGLSNPGPVRWQLALCLLAAWVIIFLCMLKGIRSSGKVVYVTATFPYLVLVVLIIRGATLEGSLQGVAFYLTPVWGRLANAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTLVITIGNCATSFFAGFAIFSILGHMAWRKGVPVEKVAISGPGLAFVAYPEALALLPGSVFWAILFFLMLFMLGVDTLFGNMEGITTAVLDEFPQLRSNMKYKTLFLGLLCFGFYLMGLLLVTNGGIYWFTLIDSSSTSFGLIIITLFMCLGISFFYGVNQFCQDIVDMICLCP----PWCTKVLLYFKACWVFFTPFLLLFILTYIFIEMYRTPLKY----GQYIYPLWGKALGVCMGAFCCLQILIWATVAVSKESGTLKDRFQ 608          

Query:   65 NPCFNANPKETRQENNIHYEVNTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW-----SPEAMQTPDPNLS----------SQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTN-LGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIY---IFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIY 1729
             P  +  PKE   E  +  E N     S+     T + H      +   ++ D++L +IG+ V +  + + PYL +K    AF +PY +F  I G+PLF +E+ +GQ    G    W   P+ K +G  ++ +++     Y + + WAL Y F +F+  LPW     +  +    D N +          +  + E       ++ G   +GLP W++  C   +  +L  +   G+    KVV+ T T+ YV + +L++  ++L G++DG+K +L +    L +  +W +AA QI   L +  G ++ FSS+ +   N   + +I + ++  TS  +     ++ GY++ +K N  + K  T+  G+ FI  P+ I+T+P ++ +A +++I+L+T+G D+A+G +  V   +++ F   +  +E + T+ I  ++F++S+    +GG+Y+F L D F+   + L   L+  I +   Y     S DI  M+ + P    ++ ++ W F+     P  ++ M+ + +  +    +G + F  + N                +G C+ +S +I + +Y
Sbjct:   19 KPSSSMGPKEV--ELILVKEQNGVQFTSSALVTSTGQTHPSGEQRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQYNREGAAGVWKICPVFKGVGFTVILISLYVGFYYNVIIAWALFYLFSSFSGELPWVNCNNTWNSANCSDLNATLLNDSHKVTPALEYFERGVLHMQDSRGIDDLGLPRWQLTCCLAVVIVVLYFSLWKGVKTSGKVVWITATMPYVVLTVLLLRGVTLPGAIDGIKAYLSVDFLRLCDAQVWIEAATQICFSLGVGFGVLIAFSSYNKFSNNCYRDAIITSSINSLTSFFSGFVIFSFLGYMS-QKHNVALDKVATDGPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDSAMGGMESVITGLIDEFKFLHRHRELF-TLFIVVLTFLISLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGIAWFYGVDRFSDDIQEMIGHRP---GLYWRLCWKFV----SPCFLLFMVVVSFATFNPPKYGSYYFPTWAN---------------MVGWCLSISSMIMVPLY 569          

Query:  173 EDHLENSNPQRI--SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINAT-------------------GTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILEL---FSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLC-TALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIG----SCVPLSVLITIGIYLMKFKGPLVKRLKGLLN-------------QNENDKPWYPVSPNDKNDLL 1840
            ED  E  +PQR   + + D++L + G  VG+G + + PYL +K    AF IPY IF F  GLP+F LEV +GQ TS+G I CW    P+   +G   + +     I Y++ + W L Y F  F   LPW+         N            +  NAT                   G  K+G   W++ LC L +W +       G+    KVVY T T  +V + +L+V  ++L G+ +G+K++L   ++ L +  +W DA  QI    ++  G +    S+ + K N   + L++  ++ +TS ++     +  G++  ++         +  G+ FIA P+ ++ +P   F+A +++I+L+ +G D+    V     S+++L   F +  Y +E ++ I +C +S+++ + +   GG+Y+F LFD ++ S   L   A    I +  +Y        +  M+   P     W K  W            V+   L    +IF    +     +++Y Y    +  GW +      C+P+ V+I I    ++  GPL++R+K +               + +N +  +P+ PN  N L+
Sbjct:   31 EDEAEGKHPQREKWASKLDFLLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQFTSQGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPELPWASCNNPWNTENCVEDTLRRNMTLRGANATNFTSPVTEFWERNVLSISDGIEKVGPVKWDLALCLLGVWVICFFCIWKGVKSTGKVVYITATFPFVMLIVLLVRGVTLPGAAEGIKFYLYPNVTRLADPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSATSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAI-VCFVSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYGADNFYDAVEDMIGYRP---NPWMKWCW-----------TVITPLLCVGCFIFSLVKYKPLTYNKIYEYPDWSIGVGWTLALASMICIPMVVVIKI----IQSDGPLIERIKAVAAPVRGGASSCPPEYRPKNTELAHPLDPNGNNGLI 613          

Query:  173 EDHLENSNPQRI--SQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINAT-------------------GTLKIGLPVWEIVLCSLAIWFLLCLAAIY-GIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILEL---FSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLC-TALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIG----SCVPLSVLITIGIYLMKFKGPLVKRLKGLLN-------------QNENDKPWYPVSPNDKNDLL 1840
            ED  E  +PQR   + + D++L + G  VG+G + + PYL +K    AF IPY IF F  GLP+F LEV +GQ TS+G I CW    P+   +G   + +     I Y++ + W L Y F  F   LPW+         N            +  NAT                   G  K+G   W++ LC L +W ++C   I+ G+    KVVY T T  +V + +L+V  ++L G+ +G+K++L   ++ L +  +W DA  QI    ++  G +    S+ + K N   + L++  ++ +TS ++     +  G++  ++         +  G+ FIA P+ ++ +P   F+A +++I+L+ +G D+    V     S+++L   F +  Y +E ++ I +C +S+++ + +   GG+Y+F LFD ++ S   L   A    I +  +Y        +  M+   P     W K  W            V+   L    +IF    +     +++Y Y    +  GW +      C+P+ V+I I    ++  GPL++R+K +               + +N +  +P+ PN  N L+
Sbjct:   35 EDEAEGKHPQREKWASKLDFLLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVALGQFTSQGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPELPWASCNNPWNTENCVEDTLRRNMTLRGANATNFTSPVTEFWERNVLSISDGIEKVGPVKWDLALCLLGVW-VICFFCIWKGVKSTGKVVYITATFPFVMLIVLLVRGVTLPGAAEGIKFYLYPNVTRLADPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSATSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAI-VCFVSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYGADNFYDAVEDMIGYRP---NPWMKWCW-----------TVITPLLCVGCFIFSLVKYKPLTYNKIYEYPDWSIGVGWTLALASMICIPMVVVIKI----IQSDGPLIERIKAVAAPVRGGASSCPPEYRPKNTELAHPLDPNGNNGLI 617          

Query:  215 RFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGT-----------LKIGLPVWEIVLCSLAI-----WFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLV-VNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFD----TALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            RFD+++  +GY +G+G + + PYL  K    AF IPY +     G+PLFLLE  +GQ TS G +  W  +P+ K +G+  V ++    I Y++ + WA+ Y + +F S LPW        +P  + + F  Y    T N T T           L  GL     V   LAI     W ++      G+ +  KVVYF+ T  YV +F+L    I+L G+ +G+ +++      L + A+W DAA QI     L  G ++   S+     N+   +++I+  ++  TS+ A     +  G++ ++ K   + L   +  G+ F+A PQ ++ +P +  ++ +++ +L+ +G D    T  GFV  +S    +    +   KE ++ + IC IS+I+ +     GGLY+F +FD +S S         ++++ LV ++   IS        ND I   I  K+  ++ + W
Sbjct:   16 RFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLVFAGIPLFLLETSLGQYTSVGGLGVWKLAPMFKGVGLASVVISFYLNIYYIVIISWAIYYLYNSFTSMLPWQ----DCNNPWNTDKCFSNYSILDTTNLTSTVVEFWERNMHQLSSGLDEPGQVRGPLAITLAISWVMVYFCIWKGVAWTGKVVYFSATFPYVMLFVLFFRGITLPGAKEGILFYITPDFRRLTDSAVWLDAATQIFFSYGLGLGSLVALGSYNPFHNNVYNRDSIIVCCINSVTSVFAGFVIFSIVGFMSHITKKPVKELA-ASGPGLAFLAYPQAVTQLPISPLWSILFFSMLLMLGLDSQFCTVEGFVTALSDEYPQYLRGH---KEIFIAV-ICVISYIIGLANITQGGLYVFKMFDYYSAS--------GMSLLFLVFFETIAISWCYGVDRFNDNICEMIGHKVHKWWNICW 467          

Query:  302 AAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP----------------------EAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRIS--DLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVG--FIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
             AF IPY +     G+PLF +E+ +GQ    G I  W    P+ K +G  +  +       Y   + WAL Y + +F S LPW+                       +  ++P     ++  LE Q  K +   G L+     W+++LC   I+ ++  +   G+    KVV+ T T  YV +FIL++   +L G+  G+ ++L+ +   L    +W DAA QI   L    G ++  +S+ +   N   + L+ + V+  TS ++        GY+   + N ++     ++G    FI  P+ I+ +  + F+A +++++++T+G D+  G +  +  ++++ +      +  Y  +G+  I F+ ++     GG Y+  L + F +  + +   LL  I +   Y       DI+ ML   P
Sbjct:    1 GAFLIPYCLMAVFGGIPLFYMELALGQFHRNGAISIWRRICPIFKGVGFAICIINFYVAFYYNTIIAWALYYLYSSFTSTLPWTKCDNPWNTVNCTSYFDTTGVAWGKHSRSPAEEFYTRNVLEIQYSKGLGGVGGLR-----WQLLLCLFLIFTIVYFSLWKGVKTSGKVVWVTATFPYVVLFILLIRGATLPGAWRGVLFYLKPNWKKLLTTEVWVDAAAQIFFSLGPGFGVLLALASYNKFNNNCYRDALVTSSVNCFTSFMSGFVIFTVLGYMAEMR-NVEVEDVAKDMGPSLLFITYPEAIANMMGSTFWAILFFMMMITLGLDSTFGGLEAIITAVMDEYPSLFSKRREYFVLGLVTICFMGALSTLTYGGAYIVKLLEEFGSGCSIIGIVLLEAIAVSWFYGVKRFCADIHSMLGFSP 419          

Query:  302 AAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFN-SNLPW-------------------------SPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKN---NYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTAL-LVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIG----SCVPLSVLITIGIYLMKFKGPLVKRLKGL 1774
             AF +PY +    +G+PLF LEV +GQLT +G I  W   PL   +GV  + +     + Y++ + W+L Y   +   + LPW                         S  A    D    +  F E    +   ++G   +G   WE++LC LA+W L+  +   GI +  KVVY T ++ YV + +L+V  + L G+LDG+ Y+L+   + L    +W +A+ Q+     +  G +    S+ +   N   +++I+T ++ +TS  +     ++ G++  ++         T  G+ F+  P+ IS +P    +A + +I+L+ +G D+    +      + +LF         +EA+  +  C +SF++S+ +   GG+Y+F LFD+++ S   +   +    I +  +Y       D+  ML   P     W    W  +        + L IF+ + ++      +   V +  Y Y     A GW +      C+P   L      L   KG L +R + L
Sbjct:    1 GAFLVPYGLTVVCVGIPLFFLEVALGQLTQQGTIGVWKIVPLFTGVGVASMVVVFLSDLYYIVVLAWSLYYLLHSLTTAQLPWTHCQGWWATAACSDTLGTSRAASNASEGASACQDTTSPAVEFWERNVLRV--SSGMHDLGSVNWEMLLCLLAVWLLVYFSVWKGIKFSGKVVYVTGSVPYVLLLVLLVQGVMLPGALDGITYYLQPDWAKLATPQVWVEASTQVFYCYGVGFGVLPALGSYNKFHNNCYRDSIILTIINSATSFFSGFVVFSFLGFMAQEQGVDISHVAETGPGLVFVVYPRAISLLPVPALWATLLFIMLLLLGVDSEFAGMEGFVTGLTDLFPSQLSGKRRREAFTGL-CCLVSFLLSVTMVTQGGIYVFQLFDSYAASGISMLWLMGWECIAVAWVYGANRFMQDLTAMLGFRP---HAWVWWCWSVV-----SPAVCLGIFVFHLVH------YERLVYNGRYEYPGWAEALGWLLALSSMLCIPAVALYK----LATAKGSLAQRWRHL 506          

Query:  740 KVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSK---NNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNS-WTKLCTALLVTIMMLVLYKGTEISTD-INFMLSNDPITLKIWKKIKWYFIVLWYGP---VQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGI----YLMKFKGPLVKRLK 1768
            +VVYFT T  Y+ + IL ++ ++L GS DG+ Y+L+   S LG   +W DA  QI    ++  G +    S+ +   N   +T I+  V+  TS  A     +  G++  ++         +  G+ FIA P+ +S +P A  +A +++ +L+ +G D+    V      I +LF       Y +E +V +  C  SF+++I +   GG+Y+F LFD +S S  T L  A    I++  +Y G +   D I  M+   P     W +  W F+     P     I L   L YK       P T Y    VY +    L  GW    C+ LS ++ I +     L + KG L++R +
Sbjct:    1 QVVYFTATFPYLVLIILFINGMTLPGSYDGIMYYLKPDWSKLGQPQVWIDAGTQIFFSYAIGLGALSALGSYNRFNNNCYRDTFILALVNSGTSFFAGFVVFSTLGFMAAEQGVDISQVAESGPGLAFIAYPKAVSLMPMAPLWAALFFFMLILLGLDSQFVGVEGFVTGISDLFPAALTGGYRREVFVGV-CCFTSFLIAISMVTEGGMYVFQLFDYYSASGMTLLWQAGWECIVVAWVYAGGDRFMDNIALMIGYRPFP---WMRWCWAFVT----PCVCTGIFLFNLLNYK-------PLT-YNKGYVYPWWGEAL--GW----CMALSSMLCIPVVAIYRLARTKGNLLERWR 335          

Query:  185 ENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMV------ALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP------------------------------EAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL 844
            EN+     + + +Y+L MIG  VG+G + + PYL +K    AF IPY I    +GLPLF LE  +GQ  S G I  W   PLLK LG  MV      AL  N +I Y ++      Y F +F S LPWS                                + QTP     ++  L     ++++ TG +     VW + L  L  W + C A + GI    KVVYFT    YV + IL++   +L G++ G++Y++
Sbjct:    2 ENAERGNWASKSEYMLSMIGNAVGLGNLWRFPYLAYKNGGGAFLIPYIIMLAFVGLPLFFLECSIGQFASLGPITIWKVVPLLKGLGWMMVITSSLIALYYNSIIAYGLF------YLFASFTSELPWSSCKKWWGADENCFDRSVCNSSLAEGNCSSVNSSKQTPSEQYWNKYALRRS--ESMDETGDV-----VWHLALTLLLSWIVTCAALVKGIKSSGKVVYFTAIFPYVVLIILLIRGATLPGAILGIEYYI 245          

Query:  131 TAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW--SPEAMQTPD----------PNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI 1537
            TA  N   +N D  +D +   + +R  ++ +++   IG+ VG G   + PY+  K    AF IPY +F  + G+PLF +E+ +GQL   G I+ W    PL   +G   + ++    I Y + + W+L + + +F +++PW     +  TPD            +SS R    +    I  +     GL V  + LC L  W L+  +   GI    KVVY T T+ Y+ + I  +  ++L G++DG+ YF+  +   L +  +W DAA QI+  L++  G ++ F+S+   K N+  + L+I+ ++ +TS+ A     A  GY+   +        +   G+ FI  P  IS +P    +A +++++L+ +G D+  G V +V+ +++E + +  +     V + IC + F++ +   + GG+++F LFD+FS   + L       +++  +Y     + +I+ M+    +    W  I W +I
Sbjct:    2 TADSNKPLKN-DEKKDLVTVESRERWDRKIEFLFACIGFAVGYGNFWRFPYMCFKNGGGAFLIPYVLFLCLGGIPLFFMELSLGQLLQEGPIKAWQKICPLFSGIGFASIVISFIVSIYYNVILAWSLYFLYNSFFADIPWVGCHHSWNTPDCYVYNASANASGVSSSREFLVKNVLEITKSIEEPGGLSV-HLTLCLLVAWILVYFSIWRGIRTTGKVVYVTATLPYIILVIFFIKGVTLPGAIDGVLYFITPQWDRLQDPKVWIDAASQILYSLTIGFGVLIGFASYNPRKNNVFSDALLISVINCATSVFAGFVIFAIVGYMAHVQEKSVPEVASQGPGLVFIVYPAAISQLPFPQIWAVIFFLMLIALGLDSQFGQVEVVAAALIEQWPRQLHKHRELVVLVICFVMFLLGLSCVSKGGMFVFNLFDSFSCGLSLLFVVCFELLVIGWIYGARRYADNISQMIGRPVLQ---WWVICWKYI 481          

Query:   92 ETRQENNIHYEV-NTAYMNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP----------EAMQTPD-----------------PNLSSQRFLE---YQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELF---SKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI 1537
            E  + N+    +  +   + +   +D  E+   +    + S + +++L  +GY VG G + + PYL +K   A F IPY I   + G+PLF LE+ +GQ  S G I  W    PLLK +G  +  ++    I Y++ + W   Y F++F + +PW             A ++ D                 P   S  F      +  + I+  G ++     W +    +  W ++      GI    KVVYFT T  ++ +FIL++   +LEGSLDG+ Y+L      L +  +W  AA QI   L +  G ++ F S+ +   N+  + L+I+  + STS  A     +  G++ L          T+  G+ F+A P+ IS +P +  +A +++ +L+T+G D+    +  V  +I++ +       + K  +V I +C    I+ +P    GG+++F L D      + L  ALL  I +  +Y     S D+ +M    P+    W +I W ++
Sbjct:    7 EIEESNDTKKPLFGSTSSSEDSPQIDVEEEQTRD----KWSSKAEFMLSSLGYCVGFGNVWRFPYLCYKNGGATFLIPYFIMLIVNGIPLFFLELAIGQWFSSGVIGVWKSICPLLKGIGYAICMISYLCCIYYIVILAWTFYYLFMSFQAVVPWKTCDNPWNTKFCRAKRSGDLLLNCTELDLPQNCTAKPTSPSGEFWSNNVLEMTEDISDFGDMR-----WPLFGTFILSWIVVYFCLFKGIKSSGKVVYFTATFPFIVLFILMIRGATLEGSLDGVIYYLNPDWERLADPQVWIYAATQIYWSLGVGFGALITFGSYNKFNNNVHKDALVISIANCSTSFFAGFVVFSVLGFMALTLDTTVAKVATSGPGLAFVAYPEAISQMPVSTLWAVLFFFMLITLGLDSQFATIEAVITAIVDEYPWVRGTKWRKPVFVLI-LCISLCILGLPCVFQGGMWIFNLMDYQVAGLSLLIVALLEIITIGWIYGVDRFSDDVEYMTGRRPMR---WFRICWKYV 513          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPD--PNL----SSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLG---NMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLK-----------------KFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDP 1495
            + PYL  K    AF +PY IF  I GLPLF LE+ +GQ   +  I CW    P L  +GV  + +++   + Y++ + W   +FF++F S+LPW        D  P+      S  +  +   +   +     +G+ V ++  C +  W L  L  + GI    KVVYFT T  Y+ + IL    ++LEG+ +G+K  L   D G   +  +W DAA Q+   LSL  G ++ F+S+  +   ++ +   +  V+  TS+ A I   +  GY   K                  +  + L+  +  G+ FI     +  +  +  +A +++++L+ +G D+  G +      I+EL       KE  VT+G+  I  ++ + + +  G Y+F +FD +S +   L  AL   I +  +Y     + DI FM    P
Sbjct:   28 RFPYLCQKNGGGAFLVPYIIFMLIEGLPLFFLELSIGQRMRKSAINCWRDIHPCLFGIGVACLMVSLMLCLYYIVIIAWCCYFFFISFTSDLPWKKGLKAKFDSFPDCCVRDPSAYYFYHHALEVSTSIEDTGVGINV-KLAGCLVFAWILTYLCVVKGIKSSGKVVYFTATFPYIILIILFFRGVTLEGAGNGIKT-LFTPDWGLLLDANIWKDAATQMFFTLSLGFGALIAFASYMPMHNQVMKDGYTVVLVNCGTSLFAGIVVFSILGYREAKTGIPVTEVWTIRRVSGFAYGGRGLRVGSGPGLAFITFSDAMLLMDVSPLWAILFFMMLILLGIDSEFGTLEAAIGPIMELNLFPKVRKE-LVTLGVAVILLLLGLCMTSGAGYYIFQMFDDYSVTIPLLVIALFQCIGVAWVYGNDRFADDIQFMTGKRP 460          

Query:  143 NSNCENLDTNED-----HLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGC-SPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP-----EAMQTPDPNLSSQRFLEYQG-FKTINATGTLKI-------GLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILA--CIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITI---GIYLM-KFKGPLVKRLKGLLNQNEND 1795
            +++ E L ++E+      +     ++  ++ ++ L  +GY VG+G + + PYL  K    AF IPY     I G+PLF +E+ +GQ  S G +  W    P+ K +G  M+ ++    + Y + + W L Y F +F  ++PW               NL+     EY    K       L+I       G+  W++V+C +  W L+      GI    KVVYFT T  Y+ + IL++  ++L G++ GL ++L+   S LG+  +W DAA QI   L +  G ++   S+ +   N   + + ++ ++ STS+ A   IFS   F    L K   ++   T+  G+ F+  P+ I+ +P + F++  ++ +L+T+G DT       V+  + + + +   +++   T  +C   F++ +P+ +  G ++  L+   +   + +  A    I++   Y     + DI  M  N     K+W    W+ I   Y    ++  IF+   +   G       V+   Y Y         F+G  + LS ++ I    IY M + KG  ++R + L   ++  
Sbjct:   15 DADGEGLTSDENCKIDVEIIGEEREKWGRKVEFFLACVGYAVGLGNVWRFPYLCFKNGGGAFLIPYLCMLLICGMPLFFMELSLGQFVSLGPVTSWAAICPISKGVGFAMLVVSFLCCVYYNVIIAWCLYYLFESFAKDVPWKTCDNWWNTATNCTSNLTDTALKEYSSPSKEFYENYVLRITPDIDTFGVMRWQLVVCLILAWVLVYFCLWKGIKSSGKVVYFTATFPYLVLVILLIRGLTLPGAMKGLSFYLKPNFSKLGDAIVWVDAATQIFYSLGIGFGSLIAMGSYNKFHNNCFRDAMTVSVINCSTSVFAGLVIFSVLGFMAEVLGKEVSEV--ATSGPGLAFVVYPEGIAQMPISPFWSICFFFMLLTLGLDTQFAMFEAVTTGLGDEYVRLLRNRKELFTAFLCFCCFLLGLPIVSQSGAFIMNLYVWQAGGVSLVFLAFFEVIVVAWGYGADRFALDIETMTGN-----KVW---PWWPIAWKYITPAVITGIFIFSLVQWQG-------VSYDDYQYPPWAE----FVGWVMALSSMLWIPGVAIYKMSRAKGTFMERWRSLTRPDQEQ 572          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWS--PEAMQT------PDPNLSSQ-RFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQI---LKDTTNL------------------------GVGFIAIPQVISTIPN-ANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITI 1720
            + PYL  K    AF IPY +   +LG+PLF +E+ +GQ   +G +  W    P L  +G+  V +     + Y M + W   Y F ++ S LP+S  P+ +        P+  L+ + ++  YQ    I  T     GL VW + L  L  W ++ L  + G+    K VYFT T  Y+ + I     ++LEG+  G+ +  +     L +  +W +AA QI   L +A GG++  SS+  V  N + + ++++ ++  TS+ A I   +  G+   + F   I    KD   L                        G+ FIA  + I  +P  +  +A +++ +L+T+G  +  G +  V   + +  +K    ++ +V+  IC +SF++ +  C + G Y   +FD+FS +   L   +L  I +  +Y       DI +M+S  P          WYF + W     +V+   +V  +      P T+   S   +        GW +G C+ + + ++I
Sbjct:   32 RFPYLCQKNGGGAFLIPYVLCLALLGIPLFFMELAIGQSVRQGSVGVWNYIHPYLGGVGISSVIVCFLVAVYYNMIIAWCFYYLFASWQSPLPYSYCPQVLTNSKYYDLPECGLAGRTQYYWYQNALKIAPTIDESGGL-VWPMCLSLLLAWIVVFLCMMKGVQSAGKAVYFTATFPYLVLIIFFGRGVTLEGAGPGVAHMFKPQFEKLADPRVWLEAATQIFYSLGVAFGGLIAMSSYNPVHNNCLRDAVMVSLINCGTSVFASIVIFSILGFKAHETFTECIELYTKDNVTLPGNQTVGEACKTLEYWLGQSAEGPGLTFIAFTEAIVKMPALSPLWATLFFCMLLTLGLGSMFGTLEGVITPVYD--AKLVSWRKEFVSGAICLVSFLLGLLFCQNSGEYWLQMFDSFSGTLPLLVIGMLEMIGVCWVYGSKRFEDDIEYMISKRP---------NWYFKITWRYEAPVVVAGIVVASLVGMISKPITYSAWSNSESKVIDTEYPGWGLG-CIAVIIAVSI 542          

Query:   80 ANPKETRQENNIHYEVNTAYMNSNCENLDTNEDH--LENSNP-QRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTAA-FFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTP-------DPNLSSQR-------FLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRI--SDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELF---SKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIW-KKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAG---GWFIGSCVPLSVLITIGIYLMKFKGPLVKRLK 1768
            A  KE     N H   N A+  S+ +  D+      + N+ P ++   +++++L  IGY VG+G + + PYL ++     F IPY I  F+ G+PLFL+E+ +GQ  + G I  W C PLLK +G+GM+ ++    + Y + + W   Y   +F S LPWS +A+            N SS R       F        +N+ G    G   W + LC LA W ++ L  + GI    KVVY T T  Y  + +LI+   +LEGSL G+ ++L    + L +  +W+DAA QI   L +  GG++  +S+ +   N++ +T+IIT  +  TS  A     +  G++  +K         T  G+ F+A P+ ++ +P + F++ +++++L  +G DT  G +  ++ ++L+ F    +NN  K  ++   +C   +++ + L   GG+Y F L D+FS S+  +   L + I +   Y   +   DI  M+ + P     W  K+  YF   W      +LM  L    +IF E     Y  S  Y      L G   G  +G+   L +LI   + + K  G L  R +
Sbjct:   21 AAQKEHAITQNGH---NPAHTASHDQGFDSPGPGPIVANTTPREQWGGKYEFLLSCIGYCVGLGNVWRFPYLCYRNGGGVFLIPYFIMLFVAGVPLFLMELSLGQYGAAGPITVWKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSSFQSPLPWSCDAIANAAVCSNNTAGNSSSGRARTPTEIFWNENVLGLVNSEGLHDPGPVRWPLALCLLAAWIIIFLCMLKGIRSSGKVVYVTATFPYFVLIVLIIRGATLEGSLQGIAFYLTPDWARLASAQVWSDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITTGNCCTSFFAGFAIFSILGHMAWRKGVSVGEVADTGPGLAFVAYPEALALLPGSVFWSIMFFLMLFMLGVDTLFGNMEGITTAVLDEFPQLRQNNLHKSLFLGT-LCFGFYLMGLLLVTEGGIYWFTLIDSFSTSFGLIIITLFMCIGISFFYGVNQFCQDILDMIRHCP----PWCSKVLIYFKACWCFFTPFLLMFILA---FIFLE----MYSTSLKYGSYVFPLWGKALGVCMGATCCLQILIWAIVAICKETGTLKHRFQ 595          

Query:  167 TNED-HLE--NSNPQR--ISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSP---------EAMQTPDPNLSSQRFLE---YQGFKTI-----------------------NATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL----RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDT---TNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDK 1828
            T +D H++  + NP+R   + + DYIL MIGY VG+G I + PYL +K    AF IPY     ++G+PLF LE  +GQ  S+G I  W   P+L+ +G+  V +T+   I Y + + ++L Y F +  S LPWS            +   D + ++  FLE   + G  T                         ++   + G  VW + LC L    L+  A I GI    KVVYFT T  YV I IL+V  ++LEG+ DG+++++     ++ L    +W DAA Q    LS+  GG++  SS+   + N+  +T  +T  +  TS+LA     A F  L      + I  +       G+ FIA P  +S +P +  ++ +++++L+T+G D+    + +++  +++ F +    K A VT+  C+I +++ +P     G+Y   L D F  +W  L   LL  I +  +Y G     DI  ML        +W +  W+ I         ++++ L + I  F   P T+    +V  Y    LA GW + + V + +       L K +G   +RLK L + +E   P+  +   ++
Sbjct:    3 TGQDAHVDPGDENPERGNWANKSDYILSMIGYAVGLGNIWRFPYLAYKNGGGAFLIPYFTMLVVVGIPLFFLESALGQFCSQGPINAWKAVPILQGVGIAAVVVTLVVSIYYNVIICYSLYYMFASMQSPLPWSDCFSWADSSCSNISAGDSSHTNILFLEKLMHSGNNTCASSNMSVLVQSPSEQYWDRVALQRSSSLDETGPVVWHLALCLLLSSLLVAAALIRGIKSSGKVVYFTATFPYVVILILLVRGLTLEGARDGIEFYIGSQSNLTKLTEAEVWKDAATQTFYSLSIGWGGLVTLSSYNNFQNNVFKDTFAVTLTNAGTSVLAGF---AIFSILGHMAHVYNIPVENVVKQGFGLAFIAYPDALSKLPISPLWSILFFVMLLTVGLDSQFAGIEVLTTCLVDAFPRYFKSKRAIVTVATCSILYLLGLPCVTRAGIYWVTLIDQFVATWVLLFLVLLEIIGVAFIYGGNRFIKDIEMMLGKKSFAFWLWWRACWFCI------SPCIILVILGWSIATF--SPPTY---GEV-QYPGWGLALGWAMVAFVVIWIPFVAVYNLTKARGSPWERLKSLCSPSEEWHPYLDIHRGER 589          

Query:  155 ENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECW-GCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWS----------------PEAMQTPDPNLSSQ--RFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILK-DTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS---KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLC---TALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLV-YKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGS----CVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDK---PWYPVSPNDKNDLLAFKKVT 1858
            E   ++ D+ E +   + + + ++ L + G I+G+G + + PYL +K    AFF+PY IF+   G+P+F LE  +GQ T+ G I CW    PL + +G     +  +  + Y++ + WA+ Y F  F + LPW+                  A    +PN +S    F E +  K   + G   +G   WE+ +C    WF+       G     KVVY T T  Y  + IL++  ++L G+ DG+K++L   IS L +  +W DA  QI    ++  G +    S+     N   + +++  ++  TS +A     +  G++  ++ N  I     +  G+ FIA P+ ++ +P +  +A +++++L+ +G D+    V  +  ++++++    +  Y +E  + +G+  +SF + + +C  GG+Y+F LFD ++ S   +C    A+  +I +  +Y       +I  M+   PI       IKW +++L  G    + + FL+ YK       P  +   + VY Y       GWF+      C+P+ ++  I     K  G   +R+K L   + + K       +SP   ND  A  K++
Sbjct:   21 EGSSSSLDNREYNERGQWNNKIEFFLSVAGEIIGLGNVWRFPYLCYKNGGGAFFVPYVIFFVCCGIPVFFLETALGQFTTEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIVILAWAIFYLFNCFTTELPWAGCGHYWNTENCIDYYGENATNITNPNATSPVIEFWERRVLKI--SDGIEHMGGMRWELAMCLALAWFICYFCIWKGPKSTGKVVYVTATFPYFMLLILLIRGVTLPGAYDGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNSYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQ-NVPIEAVAESGPGLAFIAYPKAVTMMPLSPLWACLFFMMLIFLGLDSQFVCVESLVTAVVDMYPETFRRGYRRELLI-LGMSVVSFFIGLIMCMEGGMYVFQLFDAYAAS--GMCLLFVAIFESICIGWVYGSDRFYLNIEDMIGYKPIFF-----IKWCWMILTPGICAAIFLFFLIKYK-------PLKY---NNVYTYPDWGYGIGWFMAMSSMVCIPVGMIWMI----WKTPGTFSERIKKLTTPSPDLKMRGKLAALSPYAANDAKADGKIS 600          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWG-CSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWS--------PEAMQTPDPNLSSQ---------RFLEYQGFKTIN-ATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS---KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLV---LYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLL------NQNENDKPWYPVSPND 1825
            + PYL  K    AF IPY +F    G+P+FLLE  +GQ TS+GCI CW    PL + +G     +     ++Y++   WA  Y F +F + +PW+           ++    N SS             E+   + +  + G  +IG   WE+ LC L  W L       G+    KVVYFT T  YV + +L+   +SL G++DGL ++L    S L +  +W DA  Q++    + +G +    S+ +   +   +T  +  V+  +S +A +   +  G+++ ++         +  G+ FIA P+ ++ +P    +A  ++I+++ +G DT    +  +  S+ ++F    +  Y +E  +   +C + F++ + L   GGLY   LFD +  S + L   LL T   L    +Y G  +  +I  M+   P  L    KI W F+      V +   IF V +       P  F   ++ Y Y S     GW +G    + V + I   + + +G L ++LK L       N   N    YP++P++
Sbjct:   54 RFPYLCFKNGGGAFLIPYILFLLACGIPMFLLETAMGQFTSQGCITCWRYFCPLFEGIGYATQVVIAYAAVSYIVIQAWAFFYLFSSFRAEVPWASCKNDWNTESCVEFDKANTSSNWSAAANATTPATEFWERRVLGISQGIEQIGSLRWELALCLLLAWILCYFCVWKGVRSTGKVVYFTATFPYVMLVVLLARGLSLPGAMDGLAFYLYPDPSRLVDPQVWMDAGAQVLFSFGICQGSLTALGSYNRFNNDCYKDTFGLCLVNGGSSFVAGLAIFSVLGFMSYEQGLPISQVAASGPGLAFIAYPRAVAMMPLPQLWAVCFFIMVILLGADTQFVSLECLMTSVTDMFPLVFRRTYRRELLLLF-LCTVCFLLDLLLVTEGGLYFLQLFDHYVCSGSNL--LLLSTCQSLAIGWIYGGDRLYDNIEDMIGYRPGPL---IKICWLFVT---PTVCLGTFIFSVVRY-----RPLKF---NKTYIYPSWAYILGWTLGLLCVIMVPLWIIFKMSQMEGTLKQKLKQLCVPEIPPNSKVNQPEEYPLNPDN 588          

Query:   77 NANPKET-----RQENNIHYEVNTAY-MNSNCENLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPW-----SPEAMQTPDPNLSSQRFLE----YQGFKTINAT--------------GTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLR--ISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTN-LGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFI 1537
            N   KE      + +N + Y  +T     + C         +E    +   ++ D++L +IG+ V +  + + PYL +K    AF IPY +F  I G+PLF +E+ +GQ    G    W   P+ K +G  ++ + +     Y + + W+L Y + +  + LPW     S  ++   DP   +  F +    Y   K   A+              G   +GLP  E+ LC + + F+L  +   G+    KVVY T T+ YV +F+L++  I+L G+L+G+K +L   +S+L N+ +W DAA QI   L    G ++ FSS+ +   N   + ++ + V+  TS ++     +  GY+  +K+N  I    T+  G+ FI  P+ IST+P + F+A V++I+L+T+G D+++G +  V   + + F     +++ + T      +F++++    +GG+Y+  L D ++   + L   L+  I +   Y     S DI  M+   P    ++ ++ W F+
Sbjct:   21 NVEKKEVELILVKDQNGVQYTNSTIIPTAARCAGPHGTSTDIER---ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYILFLVIAGMPLFYMELALGQYNREGAATVWKICPVFKGVGYAVIVIALYVGFYYNVIIAWSLYYLYSSMTAELPWLKCGHSWNSINCTDPQHINASFFDKNTSYANNKFTPASEYYERGVLHLHESKGIEDLGLPRLELTLCLVVVVFILYFSLWKGVKSSGKVVYITATMPYVVLFVLLIRGITLPGALNGIKAYLNFSLSELNNLQVWIDAATQIFYSLGAGFGVLIAFSSYNKFDNNCYRDAILTSAVNCITSFVSGFAIFSVLGYMA-QKYNMDIKAVATDGPGLVFIIYPEAISTLPGSTFWAIVFFIMLLTLGIDSSMGGMEAVITGLSDDFKFLKRNRKLF-TFATAFGTFLMALICVTNGGIYVLTLLDKYAAGTSILFAVLIEAIGVSWFYGVDRFSEDIEQMMGFKP---GLYWRLCWKFV 532          

Query:  272 KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT 1858
            KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQ+LKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIG DTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFI SIPLC SGGLYLFPLFDTFSNSW KLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGP VKRLK LLNQNENDKPWYPVSPNDKNDLLAFKKVT
Sbjct:   13 KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQVLKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGLDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIASIPLCTSGGLYLFPLFDTFSNSWAKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPFVKRLKWLLNQNENDKPWYPVSPNDKNDLLAFKKVT 541          

Query:  548 SPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPLVKRLKGLLNQNENDKPWYPVSPNDKNDLLAFKKVT 1858
             PE       +  + R+ +YQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQ+LKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIG DTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFI SIPLC SGGLYLFPLFDTFSNSW KLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGP VKRLK LLNQNENDKPWYPVSPNDKNDLLAFKKVT
Sbjct:   41 EPEYPCGDGCHCCAARYRKYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQVLKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGLDTALGFVRIVSLSILELFSKNNYDKEAYVTIGICAISFIASIPLCTSGGLYLFPLFDTFSNSWAKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVYKIYIFGEHPFTFYVNSQVYNYTSSELAGGWFIGSCVPLSVLITIGIYLMKFKGPFVKRLKWLLNQNENDKPWYPVSPNDKNDLLAFKKVT 477          

Query:  272 KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQ 955
            KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFC 
Sbjct:   13 KTPYLVHKYTAAFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDPNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFLRISDLGNMAMWTDAAIQIILILSLAEGGIMCFSSFCH 240          

Query:  158 NLDTNEDHLENSNPQRISQRFDYXXXXXXXXXXXXXXXKTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPDP-------------------------NLSSQRFLEYQGFKTINATGTLK-----IGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYLNLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIVSLSILELFS--KNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLW 1546
            N +   +  EN+     S + D+ L  +GY VG+G + + P+L +K    AF IPY     I G+PLF  E+ +GQ +S G +  W   P+ K +G  M+ +++   I Y + + W+L Y F +F S LPWS    +  D                           ++++++ +      +N  G  +     +G   W + LC L  W +   + I G+    KVVYFT    Y  I I++++   LEGSL+G+KY+L  + S L    +W DAA QI   L +A GG+M  +S+ +   N   + L+++ ++ +TS +A     A  GY+++K         T+  G+ F+A  Q ++T+P +  ++ +++ +L+T+G D+  G +  +     + F   K  +  +    I    I F + +P  + GG+Y+F L D +  S++ +  A L   ++  +Y     S DI  ML   P          +Y+I+ W
Sbjct:   12 NKEVRFEGDENTYRGNWSSKMDFFLSCVGYAVGLGNLWRFPHLCYKNGGGAFLIPYFTMLIIAGIPLFYFELSLGQFSSSGFLTVWKIQPMFKGIGFAMLVISIICSIYYNVIIAWSLYYLFASFTSKLPWSDCNNEWNDELCLNDFKNVTNVVCSSFRTTNCTKYEVAAEQYWQRVVLGVVNYAGDQRPMEPYLGTVQWHLSLCLLLAWIICGASLIKGVKSSGKVVYFTAIFPYFVIVIMVINGCLLEGSLEGIKYYLIPKWSKLLEARVWGDAATQIFYSLGVAFGGLMTMASYNKFNNNCYRDALMVSIINCATSFVAGFAIFAVLGYMSVKTGRSVAETTTSGTGLAFVAYAQGVATMPYSPIWSILFFGMLLTLGIDSQFGGMEAIFTGFQDQFPILKKTHFHDFSFKIIFQIILFFLGLPCVSKGGIYMFTLMDEYCGSFSLIIIAFLELTIISFIYGVKNFSQDIEMMLKFKP---------GYYWIICW 500          

Query:  272 KTPYLVHKYTA-AFFIPYTIFYFILGLPLFLLEVYVGQLTSRGCIECWGCSPLLKALGVGMVALTVNGLITYVMYVIWALRYFFLTFNSNLPWSPEAMQTPD-----------------PNLSSQRFLEYQGFKTINATGTLKIGLPVWEIVLCSLAIWFLLCLAAIYGIHYRVKVVYFTITISYVAIFILIVHSISLEGSLDGLKYFL--RISDLGNMAMWTDXXXXXXXXXXXXEGGIMCFSSFCQVKENLVVNTLIITFVDFSTSILACIFSSAYFGYL-NLKKFNFQILKDTTNLGVGFIAIPQVISTIPNANFFAFVYYILLVTIGFDTALGFVRIV------SLSILELFSKNNYDKEAYVTIGICAISFIVSIPLCASGGLYLFPLFDTFSNSWTKLCTALLVTIMMLVLYKGTEISTDINFMLSNDPITLKIWKKIKWYFIVLWYGPVQIVLMIFLVY 1588
            + PYLV+K    AF IPY +    +GLP+F LE  +GQ +S G I CW  SPL K +G GMV +T    + Y + V   + Y F +F S LPWS       D                  N  S     Y+ +    + G    GLP W+++LC L  W ++    + G+    K+ YFT    YV + IL++ S  L G+  G+KY+L  +   L +  +WTDAA QI   LS   GG++  +S+ + K N   + +I+  ++ +TS+ A     A  G++ N+K      +      G+ FI  P+ +S +P A  ++ +++ +++T+GF +    V  V       L    + S   + K   V   +C + F + IP+  +GG+YL  L D   + +  L   L+  +++   Y   +   DI+ M    P          WY+ + W     IV++  LV+
Sbjct:   91 RFPYLVYKNGGGAFLIPYCLMLMCVGLPIFFLEFAIGQFSSLGPISCWIISPLFKGVGYGMVIITWYLTLYYNVIVAHCVFYLFSSFTSKLPWSTCGNYWNDNTTCFDGSNNTIHLLAIENKISATEQYYEKYVLEVSKGIEDFGLPSWKLLLCLLLSWIIVTAVLLKGVSSLGKISYFTALFPYVLLTILLIRSAFLPGAGQGIKYYLTPQFYRLSDPNVWTDAATQIFFSLSCCSGGLINMASYNKFKNNCCRDAVIVALINCATSVFAGFVIFANLGFMANMKNVTIDKVAK-GGPGLAFIVYPEALSNMPMAPLWSILFFFMMLTLGFGSQFSMVETVMSGFQDELMRAGIISSEKFRKTFRVM--VCVVGFALGIPMICNGGIYLLTLLDWTVSGYPLLILGLMEILVICYFYGIRQFKKDISLMTGGRP---------NWYWRITWLIITPIVMVFLLVF 544