TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032110 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 208.379 bits (529), Expect = 1.757e-60 Identity = 157/503 (31.21%), Postives = 245/503 (48.71%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI---------------------VGAVNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP+ C + V VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAA-LLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 208.379 bits (529), Expect = 1.757e-60 Identity = 157/503 (31.21%), Postives = 245/503 (48.71%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI---------------------VGAVNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP+ C + V VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAA-LLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 199.134 bits (505), Expect = 8.213e-57 Identity = 159/528 (30.11%), Postives = 245/528 (46.40%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP-------------------------------YGCDIVGA---------------VNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP YGC G VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAA-LLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 199.134 bits (505), Expect = 8.213e-57 Identity = 159/528 (30.11%), Postives = 245/528 (46.40%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP-------------------------------YGCDIVGA---------------VNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP YGC G VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAA-LLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 196.052 bits (497), Expect = 2.243e-56 Identity = 145/465 (31.18%), Postives = 228/465 (49.03%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKT---EFQAHIRTL---VEEFIKMKKEITSLETKL--IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ ++ + L + K I + +KE ++ SK+L Q++ D E IR EE MK + SL+ ++ +ES +++ + +++S DQM + +A++ L+ + NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMA-ALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVP---MIALQVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRN---------NESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIR--------------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 477
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 135.961 bits (341), Expect = 7.721e-35 Identity = 117/458 (25.55%), Postives = 187/458 (40.83%), Query Frame = 1
Query: 91 FPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIST---MPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNSCEYLTVV-CEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGA--VNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSD-TFKPDPR-----STCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVV 1422
F L + C IC + L + ++ +C YC++C E+ +R C TII D A K+I L V C ++ GC + L + DHL+ C + + + CEKC + L H K + R V C C + + CP+++ CP+ C + + + AH C CPFV GC+ + + H+ E H+ L +E +K +E ++ +F N+ T+ IL + + IWK++ + A+ G ++ S PF + FGYKM GDG +S++ L+KG+FD L WPF + +++LDQ + D + T+ DPR +P E N A GS F S LQ Y+K+D I+++I V
Sbjct: 8 FKGGLPADCTCPICEQALRDPIKLNCDHHYCRQCFEN---ENRTPGCAACQTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAKCELNRAV-CSFCNKTIRDSDRERH------PKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMYLCDEITDLKGTYELMER-----------DMGSF-NDRQTR-------------------------------ILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQN-YVKDDKIYVQIDV 411
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 75.0998 bits (183), Expect = 1.517e-14 Identity = 72/264 (27.27%), Postives = 113/264 (42.80%), Query Frame = 1
Query: 640 VRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTIL-DQKNKTSDYSDTFKPDPRSTCY-QQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVL 1425
+ CPF E GC K N ++ H++ + H+ L + N I TKI N+ Q S+ + +I +S EK ++ I K+ +KA + +R S+ S+PFY+ +GYKM P GDG+ + SVF LMKG++DD+L WPF+ VT +IL D K + + P + ++P N G F+ ++ E+ D IF++I VL
Sbjct: 84 IDCPFKEHGCHKKGENSEVKRHVRDDRNLHLVLLCQSL-----------------------------NPIRTKI-NIQQ----------SAYVDKYVGMLQYMSIAESAFEKYGSQHTFRIPKI-GLTVVKATKNKSHR-SIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVTEFAADGD-IFIQIKVL 304
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 142.124 bits (357), Expect = 6.749e-37 Identity = 108/412 (26.21%), Postives = 178/412 (43.20%), Query Frame = 1
Query: 211 NSRQCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI--VGAVNLLAH-RKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSD--YSDTFKPDPRSTCYQQPTEEYN-IASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
++ QC K + I M + + +C + C E + +H SC V CE KC + + H KDC KR+ +C +C + L L+A CP+ CP CD + L AH R EC V C F E GC Q L H+++ AH+ +V ++S + + I+ K+ +LS INY G +WK+ + A A + + + S PFYT ++GYK+ ++ G+G G++TH+SV+ ++ G++D LL WPF + +T T+ +Q ++ +++F PDP +Q+P+ E + + G P+FIS L ++K DT+FL++ V
Sbjct: 123 DATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEF--CQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTL-----PLHAAQ-CPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVA--------LSSRQGQQIQMLKSAVSKLS------------------------------------------------INY-TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 469
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 142.124 bits (357), Expect = 7.362e-37 Identity = 108/412 (26.21%), Postives = 178/412 (43.20%), Query Frame = 1
Query: 211 NSRQCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI--VGAVNLLAH-RKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSD--YSDTFKPDPRSTCYQQPTEEYN-IASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
++ QC K + I M + + +C + C E + +H SC V CE KC + + H KDC KR+ +C +C + L L+A CP+ CP CD + L AH R EC V C F E GC Q L H+++ AH+ +V ++S + + I+ K+ +LS INY G +WK+ + A A + + + S PFYT ++GYK+ ++ G+G G++TH+SV+ ++ G++D LL WPF + +T T+ +Q ++ +++F PDP +Q+P+ E + + G P+FIS L ++K DT+FL++ V
Sbjct: 132 DATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEF--CQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTL-----PLHAAQ-CPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVA--------LSSRQGQQIQMLKSAVSKLS------------------------------------------------INY-TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKV 478
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf6 (gene:FBgn0265464 transcript:FBtr0071188) HSP 1 Score: 63.929 bits (154), Expect = 1.272e-10 Identity = 71/337 (21.07%), Postives = 134/337 (39.76%), Query Frame = 1
Query: 526 DLYADNICPKLVDK----CP---YGCDIVGA-VNLLAH------RKECVKKPVRCPFVELGCSKV--LTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSN------------FQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKI----NYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKM--SMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQ----LQEYYMKNDTIFLKIVV 1422
D++ DN + +++ CP GC +V + + L H R++ + +CPF ++ C V QL +H+K + H++ +++ F + T++ T T + N + N + +I Q + + + ++ +M L+ ++ Y NG +W++E L A V S YT GYK + I P V LS+ LM+ + D L WPFK ++ L ++ + T DT P + +P E I++ F+ + +Q + +D + +KI +
Sbjct: 151 DIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQEPQEEKCPFAKIKCDFVGRPETNQLEEHLKADMPHHMQLMLQAF-----QQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQYANGVDEQIV---QTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDPRYSNGTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNIQPRKPHV-----LSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLSQHDTIMTKPEILAFHKPREA--ISTRGFGFLEYANISNIIQLGFCADDRLLIKIEI 472
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074275) HSP 1 Score: 61.2326 bits (147), Expect = 8.663e-10 Identity = 38/148 (25.68%), Postives = 73/148 (49.32%), Query Frame = 1
Query: 991 GVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKP---DPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVL 1425
G IW+++ + + +++ + I + S F K FGY + + IY G G K ++ ++ G++D LL WP + + + I DQ +D D K +S + Q + ++I K I+ Y++ND++F+++ VL
Sbjct: 334 GHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTIFVRKKSDDFIQSNQYFHIPH---KVIT----SRNYLRNDSMFIEVRVL 473
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074273) HSP 1 Score: 61.2326 bits (147), Expect = 1.004e-9 Identity = 38/148 (25.68%), Postives = 73/148 (49.32%), Query Frame = 1
Query: 991 GVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKP---DPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVL 1425
G IW+++ + + +++ + I + S F K FGY + + IY G G K ++ ++ G++D LL WP + + + I DQ +D D K +S + Q + ++I K I+ Y++ND++F+++ VL
Sbjct: 312 GHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTIFVRKKSDDFIQSNQYFHIPH---KVIT----SRNYLRNDSMFIEVRVL 451
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257]) HSP 1 Score: 217.624 bits (553), Expect = 6.924e-64 Identity = 161/519 (31.02%), Postives = 244/519 (47.01%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMPDNAI------NKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNSCEYLTVVCE--KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVN--LLAHRKECVKKPVRCPFVELGCSKVLTNQQL--------SDHMK------TEFQAHIRTLVEEFIK---------------------MKKEITSLETKLI--------ESSKTFKLE--------LSNFQNEISTKISNVDQMXXXXXXXXXX--XXXXXXXXXXXMANILKSNDEKINYR-------------------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
C C +L N QT+CG R+C+ CI + L C + + ++ I N+EI L V C + GC + L+ + +HL C Y V C KCK +M K +P HL + C R V C C +M L K + + +CP CP C + L +H+ +C K V C F+ GCS NQ++ S+H++ T +A + + E ++ M+++ LE KL+ S K ++E L + E+ T +V+ M + SL SS +S + + +S+ L +D+ ++ NG IWK+ + K A +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K+ V
Sbjct: 56 CETCRLVLCNPRQTECGHRFCESCINELLSKPNPV----CPADLLPLFEDKIFRDVCCNREIMALKVYCRSEKNGCKEQMCLQQVMEHLVICPYFEVPCPLGKCKEKMMRKDMPEHLSRKCKHREVTCEFCSLKMALTELQK-----HKETVCPAFPVACPNHCSFSSILRSELSSHQHDCPKAQVTCSFIRYGCSYKGLNQEMREHESSFASEHLRMMAVRNTTLEAKVEDVKSELMERYKVLPSLSSRLAEVERQYEEMREKNRQLEQKLVSMQMLMSSHSEKLLEVEMELRELRPLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 565
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 162.925 bits (411), Expect = 8.581e-44 Identity = 127/491 (25.87%), Postives = 220/491 (44.81%), Query Frame = 1
Query: 40 SLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQTKGCSTIISTM-PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHR--KECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKK----EITSLETKLIESSKTF----------KLELSNFQN---EISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDE-KINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGK-STHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPK---FISFTQLQEY----YMKNDTIFLKIVV 1422
S+S+++P + + Y F L +C IC L +A+QT CG R+C CI + ++ Q C + + PDN +EI L VKC GC+ + L+ + HL+ C + T C +C+ +P L H + C++RI+ C +C Y + + CP C Y C++ + LA +C+K PV C F GC + +T +L+ HM+ Q H+R + EF++ + + S L + K EL N + E+ ++ DQ + + + ++ +S E + G+++W+VE+F N E G I + S PFYT GYK+ ++++ + S +S+F M+G+FD L WP + + L +LDQ + + + + P +Q+PT N PK +++F LQ ++K D + ++ V
Sbjct: 45 SVSSSMPPDQQGY-DVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNH------EQFCPFANTVCEY-CEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMA-EFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV-EGQHHIEVMETKPDLQAFQRPTVMRN-----PKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 162.925 bits (411), Expect = 8.581e-44 Identity = 127/491 (25.87%), Postives = 220/491 (44.81%), Query Frame = 1
Query: 40 SLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQTKGCSTIISTM-PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHR--KECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKK----EITSLETKLIESSKTF----------KLELSNFQN---EISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDE-KINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGK-STHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPK---FISFTQLQEY----YMKNDTIFLKIVV 1422
S+S+++P + + Y F L +C IC L +A+QT CG R+C CI + ++ Q C + + PDN +EI L VKC GC+ + L+ + HL+ C + T C +C+ +P L H + C++RI+ C +C Y + + CP C Y C++ + LA +C+K PV C F GC + +T +L+ HM+ Q H+R + EF++ + + S L + K EL N + E+ ++ DQ + + + ++ +S E + G+++W+VE+F N E G I + S PFYT GYK+ ++++ + S +S+F M+G+FD L WP + + L +LDQ + + + + P +Q+PT N PK +++F LQ ++K D + ++ V
Sbjct: 45 SVSSSMPPDQQGY-DVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNH------EQFCPFANTVCEY-CEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMA-EFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV-EGQHHIEVMETKPDLQAFQRPTVMRN-----PKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 162.925 bits (411), Expect = 8.581e-44 Identity = 127/491 (25.87%), Postives = 220/491 (44.81%), Query Frame = 1
Query: 40 SLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQTKGCSTIISTM-PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHR--KECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKK----EITSLETKLIESSKTF----------KLELSNFQN---EISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDE-KINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGK-STHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPK---FISFTQLQEY----YMKNDTIFLKIVV 1422
S+S+++P + + Y F L +C IC L +A+QT CG R+C CI + ++ Q C + + PDN +EI L VKC GC+ + L+ + HL+ C + T C +C+ +P L H + C++RI+ C +C Y + + CP C Y C++ + LA +C+K PV C F GC + +T +L+ HM+ Q H+R + EF++ + + S L + K EL N + E+ ++ DQ + + + ++ +S E + G+++W+VE+F N E G I + S PFYT GYK+ ++++ + S +S+F M+G+FD L WP + + L +LDQ + + + + P +Q+PT N PK +++F LQ ++K D + ++ V
Sbjct: 45 SVSSSMPPDQQGY-DVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNH------EQFCPFANTVCEY-CEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMA-EFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV-EGQHHIEVMETKPDLQAFQRPTVMRN-----PKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 158.688 bits (400), Expect = 7.558e-43 Identity = 124/488 (25.41%), Postives = 218/488 (44.67%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQ-TDCGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTM-PDNAINKEIGKLMVKCLY--DGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEI----------------------LMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIR--TLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKN----KTSDYSDTFKPDPRSTCYQQP------TEEYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
KRRF +C +CS+ + +Q + CG R+C C+++ L +C + + PD + ++I L ++C++ +GC +K + H ++C + + C +C +++ + LP HL DC KR VKC CGS E +M+ L + CPK C Y + H+ C + PV+CP + G + + L++H+K + + E K + ++ L ES+K+ + + +I + + M + S+D GV IWK+ + A+ N S PFYT +GYK+ + + G+G G+ +HLS++ ++ G++D+LL WPF KVT +ILDQ + K ++TF PDP +Q+P +E + G PKFIS ++++ Y+++++IFLK +
Sbjct: 13 KRRF--------QCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCP-NQCGTPNI-AREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMCSLVGRQRQEILELRR---------------------EMEELSVSHD-------GVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 194.897 bits (494), Expect = 1.882e-55 Identity = 147/501 (29.34%), Postives = 239/501 (47.70%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS---TMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNS-CEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAV-------NLLAHRKECVKKPVR-----CPFVELGCS-------------KVLTNQQLSDHMKTE-FQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYR-------------------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K RF + + KC C +L N QT+CG R+C+ C+ + +++S Q C I+ DN +E+ L + C + GC L ++ HL S C++ + C + CK ++ K L +H+ K C R C C +++ + M+ H D+ CP +V CP+ C + + + AH + V ++E S ++L NQ S ++ E + +R I++++ I KL + K + L +E SN + + N L+ + + + + +D+ ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KV+L ++DQ D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 35 KERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCM-NAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPL-VEMQKHEDVD----CPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIR-NLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 528
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 182.57 bits (462), Expect = 1.092e-50 Identity = 147/523 (28.11%), Postives = 233/523 (44.55%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS---TMPDNAINKEIGKLMVKC-------------------LYDGCNHEEM------------LKDIGDHLN-SCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLN-CGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGA-VNLLAHRKECVKKPVR-----CPFVELGCS-------------KVLTNQQLSDHMKTE-FQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYR-------------------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K RF + + KC C +L N QT+CG R+C+ C+ + +++S Q C I+ DN +E+ L + C L C EE+ KD+ DH+ +C+Y C+ C+ ++P + H DC ++ C + C + + HL L N P YGC G + AH + V ++E S ++L NQ S ++ E + +R I++++ I KL + K + L +E SN + + N L+ + + + + +D+ ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KV+L ++DQ D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 35 KERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCM-NAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHL-LECVN-APSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIR-NLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 553
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 181.03 bits (458), Expect = 2.764e-50 Identity = 153/516 (29.65%), Postives = 236/516 (45.74%), Query Frame = 1
Query: 91 FPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIED--HLVNSRQCQTKGCSTIIS--TMPDNAINKEIGKLMVKCLYD-GCNHEEMLKDIGDHLNSCEYLTVVC--EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEY----------------EILMKFHLDLYADNICPKLVDKCP---YGCDIVGAVNLLAHRKECVKKPVRCPFVE----LGCSKVL-----TNQQLSDHMKT-EFQAH------------------IRTLVEEFIKMKKEITSLETK---------LIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINY-----RNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE----YYMKNDTIFLKIVV 1422
F L D KC C +L N QT CG R+C+KCI + L + QC I S DN +E+ L+V C C+ + ML +HL C Y +C + C +M K L HL +C R C+ C M +I F LD + CP+ +C YGC+++ + L+ V C F LG + L QQLSD +K E + H + + +++ + +++++ L +K ++++ ++ K LS + +I N+D L S+ + + SN+E+ NG IWK+ + K A G +S+ S+ FYT GY++ + Y GDG GK + LS++F +MKG+FD +L+WPFK KVTL +LDQ K + +D F+ DP S+ +++P E NIASG P+F S QL+ Y+K+DT+F+KIVV
Sbjct: 34 FVEQLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCPIDM-ENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSLCLACLDYMFSCRNNYKKIFFSFQLDKHLCE-CPEAELQCTFSNYGCNVMVLYHSLS-----VHFLYLCTFTSVSQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLE-AYKDRIDNLDGQFKKHDVLLSNHKMQ-----------MTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVV 530
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 174.481 bits (441), Expect = 1.239e-48 Identity = 131/454 (28.85%), Postives = 212/454 (46.70%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMPDNAIN-KEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYA-DNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVR------CPFVELGCSKVLTNQQLSDHMKTEFQAHI---------RTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ--EYYMKNDTIFLKIVV 1422
C C LL +Q CG RYC C+ + II + N E + + + G L +G H C YL C CK + H ++C +R + C C L + D+ A D ICPK P C+ G RK+ ++ VR C + +GC++++ N + +H H+ K+ + + +T L + + TF+ +S E+ ++++ + + TL +A + + + +++ +GVFIWK+ F + + +A G ++ S PFYT ++GYKM ++IY GDG G++THLS+FF +MKG+ D LL WPF KVTL +LDQ N+ D F+PD S+ +Q+P E NIASG P F ++L+ Y+++DTIF+K++V
Sbjct: 37 CSDCKNLLRRPLQAQCGHRYCSHCL---------------NKIIRWVARNWGGVPECPAVCERSDWTG-----ALISVG-HEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCK-------LSFYFPDIKAHDEICPKF----PMTCEGCG-------RKKIPREKVRLFVCMPCRYAAVGCTEMVENDKCLEHENKSLAEHLAKGSPAPPANAPPNNSAKVAEMLLKFDT-LDKKNTTFENIVSVLNREVERSSHAAEELARQLRAADTRLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNR-EHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 449
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 163.31 bits (412), Expect = 2.783e-44 Identity = 114/400 (28.50%), Postives = 189/400 (47.25%), Query Frame = 1
Query: 358 HLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYA-DNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVR---------------CPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKL----IESS-----KTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI------------------LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ--EYYMKNDTIFLKIVV 1422
H C YL C CK + H ++C +R + C C L + D+ A D ICPK P C+ G RK+ ++ VR C + +GC++++ N + +H H+ + + +KE L ++ ++ S T + + F+N +S V++ S+++ L + + + + + +++ +GVFIWK+ F + + +A G ++ S PFYT ++GYKM ++IY GDG G++THLS+FF +MKG+ D LL WPF KVTL +LDQ N+ D F+PD S+ +Q+P E NIASG P F ++L+ Y+++DTIF+K++V
Sbjct: 96 HEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCK-------LSFYFPDIKAHDEICPKF----PMTCEGCG-------RKKIPREKVRLFVCSFSRNITLSLPCRYAAVGCTEMVENDKCLEHENKSLAEHLAKVWDYIQHGRKEQNDLSVRMGSLSVQGSPAPPFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAAQEKVEALTTKVRQLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNR-EHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 209.149 bits (531), Expect = 7.097e-61 Identity = 159/502 (31.67%), Postives = 246/502 (49.00%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS--TMPDNAINKEIGKLMVKCLYDG--CNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI---------------------VGAVNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L N QT+CG R+C+ C+ L +S T +II DN +EI L V C +G C + L + HL N C++ + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP+ C + V VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 39 KEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-----HEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 209.149 bits (531), Expect = 7.097e-61 Identity = 159/502 (31.67%), Postives = 246/502 (49.00%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS--TMPDNAINKEIGKLMVKCLYDG--CNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI---------------------VGAVNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L N QT+CG R+C+ C+ L +S T +II DN +EI L V C +G C + L + HL N C++ + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP+ C + V VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 39 KEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-----HEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 203.756 bits (517), Expect = 3.509e-59 Identity = 140/475 (29.47%), Postives = 224/475 (47.16%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQT--------KGCSTI--ISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGD-HLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYAD-NICPKLVDKCPYGCDIVGAVNLLA-----HRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLET---KLIESSKTFKLELSNFQN----------------EISTKISNVDQ-MXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKF--ISFTQLQEYYMKNDTIFLKIVV 1422
C C +L Q CG RYC C+ L + Q C +G S + S PDNA +E+ L C DGC + LK+ H C +L C CK + +H ++C KR + C +C + H+DL +CPK P CD G + H + C K V C F +GCS+++ + L DH + H+ L+ F++ + +L +L++ + + +++ F+N E ++ +DQ + + ++ +MA++ K ++ +++ +GVFIWK+ F + A G ++ S FYT +GYKM +++Y GDG G+ THLS+FF +MKG D LL WPF KVTL +LD N+ D F+PD S+ +Q+P + NIASG P F +S + + Y+++D IF+K +V
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCS-------HVDLEVHYEVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 201.06 bits (510), Expect = 3.374e-58 Identity = 138/482 (28.63%), Postives = 223/482 (46.27%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKG---CSTII---------------STMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGD-HLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYAD-NICPKLVDKCPYGCDIVGAVNLLA-----HRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLET---KLIESSKTFKLELSNFQN----------------EISTKISNVDQ-MXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKF--ISFTQLQEYYMKNDTIFLKIVV 1422
C C +L Q CG RYC C+ L + + G C+ + S PDNA +E+ L C DGC + LK+ H C +L C CK + +H ++C KR + C +C + H+DL +CPK P CD G + H + C K V C F +GCS+++ + L DH + H+ L+ F++ + +L +L++ + + +++ F+N E ++ +DQ + + ++ +MA++ K ++ +++ +GVFIWK+ F + A G ++ S FYT +GYKM +++Y GDG G+ THLS+FF +MKG D LL WPF KVTL +LD N+ D F+PD S+ +Q+P + NIASG P F +S + + Y+++D IF+K +V
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCS-------HVDLEVHYEVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 503
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 199.519 bits (506), Expect = 3.779e-57 Identity = 161/527 (30.55%), Postives = 246/527 (46.68%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS--TMPDNAINKEIGKLMVKCLYDG--CNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP-------------------------------YGCDIVGA---------------VNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L N QT+CG R+C+ C+ L +S T +II DN +EI L V C +G C + L + HL N C++ + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP YGC G VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 39 KEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-----HEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 559
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 2.455e-58 Identity = 140/475 (29.47%), Postives = 224/475 (47.16%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQT--------KGCSTI--ISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGD-HLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYAD-NICPKLVDKCPYGCDIVGAVNLLA-----HRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLET---KLIESSKTFKLELSNFQN----------------EISTKISNVDQ-MXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKF--ISFTQLQEYYMKNDTIFLKIVV 1422
C C +L Q CG RYC C+ L + Q C +G S + S PDNA +E+ L C DGC + LK+ H C +L C CK + +H ++C KR + C +C + H+DL +CPK P CD G + H + C K V C F +GCS+++ + L DH + H+ L+ F++ + +L +L++ + + +++ F+N E ++ +DQ + + ++ +MA++ K ++ +++ +GVFIWK+ F + A G ++ S FYT +GYKM +++Y GDG G+ THLS+FF +MKG D LL WPF KVTL +LD N+ D F+PD S+ +Q+P + NIASG P F +S + + Y+++D IF+K +V
Sbjct: 34 CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCS-------HVDLEVHYEVCPKF----PLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNR-EHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 199.519 bits (506), Expect = 2.644e-56 Identity = 161/527 (30.55%), Postives = 246/527 (46.68%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS--TMPDNAINKEIGKLMVKCLYDG--CNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP-------------------------------YGCDIVGA---------------VNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L N QT+CG R+C+ C+ L +S T +II DN +EI L V C +G C + L + HL N C++ + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP YGC G VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 39 KEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-----HEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 559
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2) HSP 1 Score: 199.134 bits (505), Expect = 3.944e-56 Identity = 159/528 (30.11%), Postives = 245/528 (46.40%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEYLTVVCEK--CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP-------------------------------YGCDIVGA---------------VNLLAHRKECVKKPV---RCPFVELGCS-KVLTNQQLSDHMKTEFQAH-IRTLVEEFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
K +F + D KC C +L + QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + ML + HL N C + + C + CK ++ K L +H+ K C R C +C S++ L K + D CP +V CP YGC G VNLL ++K V + VE S + L NQ S ++ E Q +R + + +++ I S KL E + + K + + QN + T++ +VD+ + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAA-LLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 188.348 bits (477), Expect = 1.295e-52 Identity = 137/474 (28.90%), Postives = 217/474 (45.78%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQT--------KGCSTI--ISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGD-HLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLA-----HRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEI---TSLETKLIESSKTFKLELSNFQN----------------EISTKISNVDQ-MXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKF--ISFTQLQEYYMKNDTIFLKIVV 1422
C C +L Q CG RYC C+ L + Q C +G S + S PDNA +E+ L C DGC + LK+ H C + C CK + HL +C +R + C +C + + H +CPK P CD G + H K C K V C F +GC + + ++ +H + H+ L+ ++ K + + ++L++ ++ + + + F+N E ++ +DQ + S ++ +MA++ K + + + +GVFIWK+ F + A G ++ S FYT +GYKM ++IY GDG G+ THLS+FF +MKG D LL WPF KVTL +LDQ N+ D F+PD S+ +Q+P + NIASG P F +S + + Y+++D IF+K +V
Sbjct: 34 CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH------EVCPKF----PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNR-EHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIV 496
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1) HSP 1 Score: 187.578 bits (475), Expect = 6.182e-52 Identity = 157/530 (29.62%), Postives = 234/530 (44.15%), Query Frame = 1
Query: 88 RFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIED--HLVNSRQCQT-KGCSTIISTMPDNAINKEIGKLMVKCL-YDGCNHEEMLKDIGDHLNSCEYLTVVC--EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCP------------------------------YGCDIVGAV-NLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKT--EFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQ--------------------------------NEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI------LKSNDEKINYRNGV-----FIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEY---YMKNDTIFLKIVV 1422
+F L + KC C +L N QT CG R+CQ+CI L + C K DN +E+ L V C GCN +L DHL C + V C E C+ M K + HL C R KCL C + +I++ +L + +N CP CP YGC + G NLL H + ++ + + L + L Q++SD ++ + ++ I+ L E K +KE+ T++ + TF LSN Q + + +V Q + L ++ A+I L N+E+ G IWKV + K A G+ +SV S+PFYT GY++ + Y GDG GK THLS++F +M+G+FD LL WPF+ +VTL +LDQ K + +TFK DP S+ +++P E NIASG P+F+S + L+ Y+K+DT+FLK+ V
Sbjct: 34 QFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYC----KRDIVVT-NLQDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHM---LLVLEKNYQL-EQRISDLYQSLEQKESKIQQLAETVKKFEKELKQF-TQMFGRNGTF---LSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 550
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1) HSP 1 Score: 530.406 bits (1365), Expect = 0.000e+0 Identity = 260/460 (56.52%), Postives = 335/460 (72.83%), Query Frame = 1
Query: 34 MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFL 1410
MS L++NLP NIKRYRK+ FPFN++DNLKC+ICS+LLL A+QTDCGCRYC++C++++ + +C T GC + + +PDNA+N+EIGKL VKCL+ GC H E+LKDIGDHL+SC + T+ C+ C E+ L H K C R+V C +CG MEY L + HL+++ + +C KLV KCPY CD VNLL HRK C KKPV C F E+GC++V+T + L H E H R L++E I MK +I+ L+ K +E + K+E S FQ+EI KI +++++ + + ++S++EK YRNGVFIWK+E F ELK+ AERGNRIS+TS+ FYTKEFGYKMSMKIYPAGDGVGK THLSVFFTLM+G+FDDLL WPFKNKVTLTILDQKNKT+D+SDTFKPD RSTCYQQPT++YNIASGSPKFI+F+QL E Y+ +F
Sbjct: 1 MSLLNSNLPTNIKRYRKKHFPFNISDNLKCIICSQLLLEALQTDCGCRYCKECLKEYQAKGKTKCLTDGCGDLGNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCNRVMTKEDLIKHNNEESLQHSRLLMKEIITMKNDISELKMKTLEFN-ILKIEFSKFQSEILDKIKSLEKIPRHTSP---------------STSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLLQWPFKNKVTLTILDQKNKTNDHSDTFKPDVRSTCYQQPTDDYNIASGSPKFITFSQLDEIYLXXXILFF 444
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 374.4 bits (960), Expect = 1.602e-122 Identity = 194/460 (42.17%), Postives = 288/460 (62.61%), Query Frame = 1
Query: 67 IKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS-RQC--QTKGCSTIIST-MPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETK---LIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVL 1425
+K Y+ ++ F + DNLKCV+C ++LL+A+QTDCGCRYC++CI+++L N ++C + + C ++I++ + D A NKEI L VKCLY+GC E+ LK I HL+ CEY +C C +E K NHL +C+ R V C C + + ++ + HL + ++C K CPYGC VNLL HRK C KP+ CP C +++ Q+++H+ T H T+V E K++K+ +E + LIE ++ K L + ++ ++ + LK ++ I +RNG ++WK++ F +L+ NA RG ++ SE FYT +FGYKM MKIYP GDGVGK THLS+FF +MKGD+DD+L WPFKNKV +TI D +K+++ SDTFKPDP+S CYQ+P EEYNIASGSPKFISF++L+ ++K DT++++I V+
Sbjct: 13 LKLYKDNKWRFTINDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVITSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCKQLIPKDQMTEHLNTSSYEHTLTIVTELRKLEKQNKHMEERMNILIEENQLLKATLEVMKLDLPKNSGSISR-----------------------DTSLKRANKTI-FRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKN-FLKKDTLYIQINVI 447
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: D5JG59 (TNF receptor-associated factor-2-like protein A OS=Dugesia japonica OX=6161 GN=TRAF-2A PE=2 SV=1) HSP 1 Score: 266.929 bits (681), Expect = 8.107e-82 Identity = 149/361 (41.27%), Postives = 203/361 (56.23%), Query Frame = 1
Query: 355 DHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCS-KVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFK--LELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFI--SFTQLQEYYMKNDTIFLKIVV 1422
+H+ SC+ + CEKC ++ K NH C R+V C CG M+ + L HL+ D +C K V C C+ VNL H K C K + CPF + C +T ++L H+ E+ H +L+ + ++ +I LE++L K E++ +E KI + + +I +++ + +RN FIWK F + +AE G R+SVTS+ FYT EFGYKM +++YPAGDGVGK THLSVFF +MKG+FDDLL WPFK KVTL+ILDQ++ + +SDTFKPD RS CYQ+PT+E NIASG PKFI S Y KNDTIFLKI V
Sbjct: 3 EHIESCDLREITCEKCGIKFGAKEKANHDKDKCEMRMVNCDYCGITMKSKDLNIIHLNPDRDELCSKYVGICSNNCNETRKVNLKDHLKICPNKKLECPFHQFDCKIDKMTKEKLMKHLDEEYFNHTSSLINKVKDLESKIIDLESELHNQILITKELFEMNKKSSESRLKIEKTIE---------------ELKKKAPATSIQTIDNKNVIFRNASFIWKFTDFEVRRVDAESGGRVSVTSDAFYTSEFGYKMCLRVYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSILDQESGSKPHSDTFKPDARSACYQKPTDECNIASGFPKFILLSLIMNNSIYCKNDTIFLKIAV 348
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: L9J9C4 (TNF receptor-associated factor OS=Tupaia chinensis OX=246437 GN=TREES_T100001143 PE=3 SV=1) HSP 1 Score: 240.35 bits (612), Expect = 1.463e-69 Identity = 160/481 (33.26%), Postives = 243/481 (50.52%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTII---STMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHL-NSCEY--LTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVN--LLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVE--EFIKMKKEITSLETKL-------------IESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMA-NILKSNDEKINYR-------NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
+ +F + D KC C +L N QT+CG R+C+ C+ L++S + C I DN +EI L + C + GC + L + HL N C++ L+ V CK + K L +H+ K C R C +C S++ L K + D CP +V CP+ C + + L AH ECV P C F GC TNQQ+ H + H+ L E ++ K+ I S KL E + + K + + QN + T++ +VD+ + + L ++ + ++ D + ++ NGV IWK+ + K A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ + D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K++V
Sbjct: 40 REKFVKAVEDKYKCEKCRLVLCNPKQTECGHRFCETCMA-ALLSSSGPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLTLGHLLVHLKNDCQFEELSCVRADCKERVLRKDLRDHVEKACKYREATCSHCKSQVPMVTLQK-----HEDTECPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRV-TELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 513
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 1.847e-69 Identity = 136/445 (30.56%), Postives = 224/445 (50.34%), Query Frame = 1
Query: 115 LKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMP-----DNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDL--YADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL--QEYYMKNDTIFLKIVV 1422
+ CV C ++L+ QT CGCR C C+E+ + GC+ +++ D AI KEI +L + C GC + +KD+ +HL +CEY+ C C P K L H C I C +CG + L K H ++ DN+C K D CP+ C VN+ H C ++PV C E+GC KVL +++ +H E H L++ ++KE L + ++ E+ + ++S+ ++ ++ + QS N+ K + + R G + WKVE+ E +A++G + SE FY+ GY+M +KIYP GDG +LSV+F LMKG +DD + WPF + +++ +++ + D +P+ CY +P EE+N+A+G PKF+S QL ++ ++K+ I L++ V
Sbjct: 30 ISCVKCHQVLIEPYQTQCGCRLCSNCLEE-CSKDEESHCPGCNETMNSPSNYSKHDKAIEKEILELNIICTNKGCEYTCKVKDLDNHLETCEYIEKRCTACNESYPRKELKKHEEFTCKMIITTCEDCGLELSKGDLEKKHKNVNELIDNVCSKWRDICPFKCSEDTLVNIKDHLLTCERRPVECSLNEMGCRKVLPREEMREHFNLEANYHTVLLMDALFLLRKEHQDLSVSVSVQNERNSAEIKELKEKLSSLLTEIEDLKTKLKQFQSMYEKLENER-----NLAKCSLSETKERYGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGYRMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQIQWPFNSIISIRLVNIARRGEDRVLNMRPNINDQCYGRPKEEHNLAAGQPKFVSHLQLVNEDDFIKDGAIILRVNV 468
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 182.185 bits (461), Expect = 1.311e-51 Identity = 139/484 (28.72%), Postives = 221/484 (45.66%), Query Frame = 1
Query: 37 SSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDI-GDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGC--DIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLS------DHMKTEFQAHI-RTLVEEFIKMKKE----------ITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL--QEYYMKNDTIFLKIVV 1422
SSL N P + ++ L D C IC ++L Q CG R+ + S PDNA +E+ L C+ +GC+ +K+ H C+++ + C CK + L H ++C +R + C C ++ + K H D ICPK C GC + + H K C K C F +GC ++ Q + D + T F + +T V E + +E I + + +E S T +E N Q+ + + D++ + ++ S + K + +GVF+WK+ F + + +A G ++ S FYT ++GYKM ++IY GDG G+ THLS+FF +M+G D LL WPF KVTL +LDQ N+ D F+PD S+ +Q+P + NIASG P F ++L + Y+++DTIF+K +V
Sbjct: 10 SSLEGNKPG----FPRKILANKLEDKHLCNICQKILRRPFQAQCGHRF---------------------SPASAFPDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFKNI-KAH-----DEICPKYPMIC-EGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNREMERSAT-TMEAYNRQHRL-----DQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNR-EHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIV 454
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 156.762 bits (395), Expect = 2.098e-45 Identity = 73/146 (50.00%), Postives = 99/146 (67.81%), Query Frame = 1
Query: 988 NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
NG IWK+ + KA A +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ D FKPDP S+ +++PT E NIASG P F++ T L+ Y+K+DTIF+K+ V
Sbjct: 3 NGTLIWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 148
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 156.377 bits (394), Expect = 4.387e-42 Identity = 124/515 (24.08%), Postives = 214/515 (41.55%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQ-TDCGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTM-PDNAINKEIGKLMVKCLY--DGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCL---------------------------NCGSRMEYEILMKFHL---------------DLYADNI------CPKLVDKCPYGCDI--VGAVNLLAHRKE-CVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKN----KTSDYSDTFKPDPRSTCYQQPT------EEYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
KRRF +C +CS+ + +Q + CG R+C C+++ L +C + + PD + ++I L ++C++ +GC +K + H ++C + + C +C +++ + LP HL DC KR VKC CG+RM +L + + + D I CP+ +CP C + +L H KE C V CPF + GC + H++ ++H+ + + ++EI +EL E+S +GV IWK+ + A+ N S PFYT +GYK+ + + G+G G+ +HLS++ ++ G++D+LL WPF KVT +ILDQ + K ++TF PDP +Q+P+ +E + G PKFIS ++++ Y++++ IFLK +
Sbjct: 13 KRRF--------QCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAFENHQGICPQESVYCENKCGARMMRRLLAQHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSHLTMMCSLVGRQRQEI---------------IELRREMEELSVS------------------------------------------HDGVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKRNYIRDNAIFLKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 150.599 bits (379), Expect = 1.507e-39 Identity = 121/494 (24.49%), Postives = 218/494 (44.13%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQTKG-CSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFH--LDLYADNICPKLVDKCPYGCDIVGAVNLLAHR--KECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLV---------------------------------------EEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDE-KINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGK-STHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPK---FISFTQLQEY----YMKNDTIFLKIVV 1422
L +C IC L +A+QT CG R+C CI + ++ Q C T PDN +EI L V+C GC + L+ + +H+ C++ TV C +C+ + L H+ ++C R++ C +C + Y +FH L L+A+ +C C++ N LA +C+K PV C F GC + + L+ HM+ Q H+R + +E +M++ + LE++L+ + ELS ST+++ + + +A++ +S E + GV++W++E F N E G+ + + S PFYT GYK+ ++++ + S ++S+F M+G+FD L WP + + L +LDQ + + + + P +Q+PT + N PK +++F QLQ ++++D + ++ V
Sbjct: 64 LESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIY-AEKQFHEQLCLFANTVCEY--------CNMELIRNQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLR-ELSIRNETQSTQMTELRK---------------------KLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQA-EGQHHVEVMETKPDLQAFQRPTVQRN-----PKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 150.599 bits (379), Expect = 1.507e-39 Identity = 121/494 (24.49%), Postives = 218/494 (44.13%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQ-CQTKG-CSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFH--LDLYADNICPKLVDKCPYGCDIVGAVNLLAHR--KECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLV---------------------------------------EEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDE-KINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGK-STHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPK---FISFTQLQEY----YMKNDTIFLKIVV 1422
L +C IC L +A+QT CG R+C CI + ++ Q C T PDN +EI L V+C GC + L+ + +H+ C++ TV C +C+ + L H+ ++C R++ C +C + Y +FH L L+A+ +C C++ N LA +C+K PV C F GC + + L+ HM+ Q H+R + +E +M++ + LE++L+ + ELS ST+++ + + +A++ +S E + GV++W++E F N E G+ + + S PFYT GYK+ ++++ + S ++S+F M+G+FD L WP + + L +LDQ + + + + P +Q+PT + N PK +++F QLQ ++++D + ++ V
Sbjct: 64 LESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIY-AEKQFHEQLCLFANTVCEY--------CNMELIRNQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLR-ELSIRNETQSTQMTELRK---------------------KLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQA-EGQHHVEVMETKPDLQAFQRPTVQRN-----PKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 170.244 bits (430), Expect = 9.425e-48 Identity = 130/465 (27.96%), Postives = 211/465 (45.38%), Query Frame = 1
Query: 229 TKGCSTIISTMPDNAINKEIGKLM----------VKCLYDGCNHEEMLKDIGDHLN-SCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLN-CGSRMEYEILMKFHLDLYADNICPKLVDKC---PYGCDIVGAVNLLAHRKECVKK------PVRCPFVELGCSKVLTNQQLSDHMKTE--FQAHIRTLVEEFIKMKKEITSLETKL--------IESSKTFKLELS---------------------NFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI-LKSND-------------EKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
T GC I+ E+GKL V C + GC + ++ +H+ C + T C C ++P H C + + C N C + + HL ICP +C +GC G + L + + R +EL S + QL++ + +R L +E I + + + E+ L +++ + +L+ S +E+ T+++ +++ S + + L SA S + L ++D E +Y NG +WK+ + K +A G +S+ S+PFYT FGY+M + Y GDGVG+ THLS+FF +M+G++D LL WPF+ +VTLT+LDQ SDTFKPDP S+ +++PT + NIASG P F+S L+ Y+++DTIF+K+VV
Sbjct: 23 TAGCKQIV----------ELGKLQEHMAVCVHEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCNQQVPLAEKRKHYETRCPRYPIPCPNKCEEQSIAREELVSHL-----GICPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSLVTARSANLELKVS--MLQSQLAERANSADLLGTRVRELEKELISVGQTASKNESVLCVVQRMLAVQTERLLRLQESMQGTTRRADHDALRGDLDGTAATLHELGTRVAAIEESGGSVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETASY-NGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVV 469 HSP 2 Score: 55.4546 bits (132), Expect = 1.481e-8 Identity = 51/210 (24.29%), Postives = 85/210 (40.48%), Query Frame = 1
Query: 265 DNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNSCEYLTVVC--EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCD--IVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQ 876
DN +EI L V C D GC L + +H+ C + V C C + L NH+ C R C C ++ K + + CP+ CP C+ + L++H C K C F + GC T Q L +H Q H+ + ++ +++ L+++L E + + L L E+ ++ +V Q
Sbjct: 5 DNCCRREILALRVHCRNDTAGCKQIVELGKLQEHMAVCVHEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCNQQVPLAEKRKHY-----ETRCPRYPIPCPNKCEEQSIAREELVSHLGICPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADL-LGTRVRELEKELISVGQ 208
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 156.762 bits (395), Expect = 2.601e-43 Identity = 66/146 (45.21%), Postives = 97/146 (66.44%), Query Frame = 1
Query: 988 NGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ-EYYMKNDTIFLKIVV 1422
+G +WK+ + K A G +S+ S+PFYT FGYKM + Y GDGVG+ THLS+FF +M+G++D LL WPF+ +VTL++LDQ SDTF PDP S +++P + N+ASG P F+S L+ Y+ +DT+F+++VV
Sbjct: 267 SGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVV 412
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 106.686 bits (265), Expect = 1.903e-25 Identity = 100/419 (23.87%), Postives = 177/419 (42.24%), Query Frame = 1
Query: 112 NLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS--RQCQTKGCSTIIST----------MPDNAINKEIGKLMVKCLYDGCNHEEMLKDIG-DHLNSCEYLTV--VCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNL----LAHRKE--CVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQ--------NEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEK------INYR---------NGVFIWKVEH----FPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNK 1224
C C LL +A+QT CG R+C+ CI L+ S R C T++++ PD A+ +E+G L V+C+ +GC L + H+ C+++ V + C L +P L H+ ++C R V C C + Y L K L + C + G ++ H +E C+K CP+ LGC + L +H K + H+ + + F K +++ I+ + +L + Q E++ ++ ++S +S + + MA + S+ E + R NG+F+WK++H E AER +I S F+T +GY++ +++ +G+ H+S + L G +D L WP++ K
Sbjct: 2 RFACGSCQGLLRDAVQTHCGHRFCKPCIA-RLITSVHRSCN----DTLMNSNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQLQKHQLHCRSRRT---------RECKLCGQKSIPEDKWQHHEERRCMKNRDTCPYSPLGCLYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQID--SPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPYQLK 398
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 93.5893 bits (231), Expect = 1.121e-20 Identity = 69/225 (30.67%), Postives = 104/225 (46.22%), Query Frame = 1
Query: 91 FPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTM------PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRK-ECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLV 744
F L +C IC L +QT CG R+C+ CI H + R K C + + PDN +EI L V+C C H L+ + +H CEY V C +C++ + + L H ++C++RIV CL+C +M Y+ K H + +CP +V C + + L H + +C + V C F LGC + L+ HM Q H+R L
Sbjct: 55 FEPPLESKYECPICLMALREPVQTPCGHRFCRACIL-HSMRLRDAGPK-CPVDNAVLHEGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKD-SKNH-----EQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLA 271 HSP 2 Score: 75.8702 bits (185), Expect = 5.963e-15 Identity = 44/172 (25.58%), Postives = 80/172 (46.51%), Query Frame = 1
Query: 991 GVFIWKVEHFPELKANAERGNRISVTSEP----------FYTKEFGYKMSMKI-------YPAGDG------VGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDY-SDTFKPDPRSTCYQQPTEEYNIAS-GSPKFISFTQLQEY-YMKNDTIFLKIVVLN 1428
G+F W+VE F L S P FYT GY++ +++ PAG G+ HL++F L++GD+D L WPFK ++ ++++DQ + S + ++ DP+ + +Q+P+ N G F+ L Y+++D + ++ V+
Sbjct: 393 GIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDINTLHHRSYLRDDCLVVRCEVVT 564
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 192.971 bits (489), Expect = 1.730e-55 Identity = 137/513 (26.71%), Postives = 229/513 (44.64%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKG-------------CSTIISTMPDNAINKEIG-KLM-----------------VKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPY---GCDIVGA---------------VNLL---AHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKT---------EFQAHIRTLVEEFIKMKKEITSLETKL----IESS-KTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINY-----RNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ-EYYMKNDTIFLKIVV 1422
L +C +C L + +QT CG R+C+ C+E L +C G C I + N+++G + M V+C GC + +D+ HL CE+ C+ C +P + +HL + C K V C +CG+ E + + L + NIC + C + GC G VNLL +E + + ++ + +Q+ + + +Q + + + ++E+ L+ ++ +E++ + L +NE S + + ++ ++ +I L +D K+ +G +IWK++ + G S+ S PFY +GYK ++YP GDG+GK +HLS+FF LM+G+FD LL WPF+ KVT +LDQ ++ D DTF+PDP S+ +++PT NIASG P FIS T LQ Y+++DT+F+KI V
Sbjct: 15 LDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRGPSKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHL-QTCEKHPVVCPHCGA----EGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLNVIERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ-DRVHDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRAYVRDDTMFIKIAV 521
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 174.481 bits (441), Expect = 4.564e-49 Identity = 141/471 (29.94%), Postives = 215/471 (45.65%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIIS---TMPDNAINKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNSCEYLTVVC--EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKP-VRCPFVELGCSKVLTNQQLSDH---MKTEFQAHIRTLVEEFIKMK--------------KEITSLETK------LIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNG-----VFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL-QEYYMKNDTIFLKIVV 1422
C C ++ +A+QT CG RYC CI L++ Q C + I+ T D ++EI +L V C+ GC E L+ +H CE+ + C +C ++ LP HL +C R C C + + + H + CP CP C + L+ R E P R P +E G T + L DH +K Q V M+ + + ++E K L+ + + EL ++ K+ D + ++A++ +E++N G V +WK+ + ++ A G S S F+T GYKM +IY GDG+G++ H+S+FF +M+G+FD LL WPF+ KVTL +LDQ N D F+PDP S+ +Q+P E NIASG P F S QL Q Y+++DT+FLKI+V
Sbjct: 24 CAKCRLIVKDAVQTACGHRYCSPCISP-LLSRGPIQCDVCGSTITKPETFRDKFADREILELHVHCVNQPHGCPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKEHH-----EKTCPSYPVNCPK-C----SKELI--RVEVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIADL----EERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDN-VEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQHAYIRDDTMFLKIIV 476
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5]) HSP 1 Score: 150.599 bits (379), Expect = 1.703e-40 Identity = 134/470 (28.51%), Postives = 205/470 (43.62%), Query Frame = 1
Query: 91 FPFNLTDNLKCVICSELLLNAMQTD-CGCRYCQKCIEDHLVNSRQCQTKGC-STIISTMPD--NAINKEIGKLMVKC--LYDGCNHEEMLKDIGDHLNSCEYLTVVCEK-CKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCD---IVGAVNLLAH-RKECVKKPVRCPFVELGCSKVLTN-------QQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSND-EKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSD---TFKPDP---RSTCYQQPTEEYNIASGSPKFISFTQL-QEYYMKNDTIFLKIVV 1422
F + L C+ C LL +Q CG R C KC L +S +C GC + +PD A ++EI +L VKC + C E + + H+ C+Y ++CE C + + L HL KDC ++++ CL C + K HL+ CP L CP CD + L +H +C + + C + LGC +T +++ H KT AH++ + + +K K+ I KL +E T I ++ + ND EKI + IW++E + A+ GN ++ S F T + GY++ + GDG GK TH+SVF +++KG FD LL WPF +VT +LDQ + + + KP+P +P E N + G KF ++ Y+K DTIFLKI V
Sbjct: 35 FVYPLQKKYICLDCEGLLWYPVQIKPCGHRVCTKCYTKLLSSSARCP--GCMDELNENIPDIDKAFHEEIQELDVKCRNVEWNCKWEGCVNEFSSHVEKCDYSDILCENDCGAKFQRRFLTKHLDKDCPEKLITCLYCDEK-HLRKDKKGHLE-----NCPLLPCPCPNKCDKKLTIHRCELDSHVENDCPRTKLMCEYEVLGCGHRITGLEGGGSREKMPKHNKTNIIAHVKMVADLALKNKELIMRFSEKL---------------SEHGTLIEKHEK---------------------------RLNDLEKIAHSQ--LIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIVSRNYIKEDTIFLKISV 452
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 150.214 bits (378), Expect = 6.684e-40 Identity = 67/152 (44.08%), Postives = 102/152 (67.11%), Query Frame = 1
Query: 970 EKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ-EYYMKNDTIFLKIVV 1422
+ I+Y +G F+WK++ F E A A+ GN S+ S PFYT FGYK+ +++P GDG + +LS+F LM+G++D +L WPF+ +T+T++DQ N + S+TF PDP S +Q+PT N+ASG P+F S T L+ YM + +F+K+VV
Sbjct: 374 QAISY-DGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGM-NISETFDPDPCSISFQRPTRNINVASGCPRFCSQTVLRTRGYMNENCVFVKVVV 523 HSP 2 Score: 68.1662 bits (165), Expect = 2.586e-12 Identity = 69/269 (25.65%), Postives = 108/269 (40.15%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTI--ISTMPDNAINKEIGKLMVKC--LYDGCNHEEMLKDIGDHLNSCEYLTVVC----EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDI--VGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQM 879
L D C C L + MQ CG R+C+ CI+ L++ + TI +S D E+ L C DGC + I H C ++ V C + C M L H+ K+C R++ C+ C + + L++ HL CP +CP C + + L AH +EC C F LGC+ + L +H H+ L + + + LE +L + F E ++F+ E+ QM
Sbjct: 6 LEDRYICNACRMPLNHPMQAQCGHRFCKHCIDVILISPFPACPRDGQTIQALSVFHDRCALVEMQALPCYCHGRCDGCQWTGPVAMITVHEEVCAFIKVSCIHASDGCGEIMLRFQLAKHVEKECPFRLITCVYCQNDVPERTLIE-HL-----KKCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCRFSPLGCTYKVKKIALREHQNKHVIKHMILLGRTTGEPQPNLLELENQL----ERFDGENTSFKTELERHKYEFAQM 264
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO37750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SER6]) HSP 1 Score: 149.443 bits (376), Expect = 6.928e-40 Identity = 123/508 (24.21%), Postives = 210/508 (41.34%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTD-CGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTM-PDNAINKEIGKLMVKCLY--DGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRM---EYEILMKFHLD--LYADNI------------------------------------------------CPKLVDKCPYGCDIV----GAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQ---KNKTSDYSDTFKPDPRSTCYQQPTE-EYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
+ +NL C IC + NA+Q CG R+C C+ L +R +C + S + D+ N+ I L V C Y GC + L+ + HL C++++ C C + + + H KDC KR V C C + M + + +++ + L +D++ CP CP C + G V L R +C ++CPF +GC K + L H +EE ++ E+ S +L + Q EI++ + I++ Y + +W+++ F E +R + S FYT +GYK + ++P G+G G+ THLS++ L+ G++D LL WPF+ ++TLT+LDQ K S +F PDP +Q+P++ ++ G P+F+S L+ Y+++D +FLK+ +
Sbjct: 12 VRENLLCRICHLPVRNAVQVSVCGHRFCDSCLNHALGETRLRCPVDNTAIDYSQVYADDVTNQMIMSLTVICDYYQAGCKWKGQLRKLQGHLAECKFVSADCSNSCGARIQKRRMSEHTSKDCPKRRVCCARCKAEMSYEQLRVSLRYRNEGALVSDHVTCPRNCGERMRVQDKARHMREDCLNRWVFCQYCNTEIVFRDRQTHHQSCPSFPLSCPNNCGVAQIPRGEVELHLSR-DCRSNIMQCPFRHVGCHKQFPQRSLQRH------------IEESVQQHLELVS------------ELAIQQ-QKEINS-----------------------------LKEIVRHCKP---YHDSKLLWRIDDFWEAFDEGKRKPGTELHSPVFYTSNYGYKFKVVLFPYGNGSGEGTHLSLYIRLLPGEYDSLLPWPFEGQITLTLLDQSTDKRAKRHISQSFSPDPNWKSFQRPSKNSTSLGFGYPQFVSHRGLESIGYVRDDVLFLKVTI 461
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 201.06 bits (510), Expect = 7.682e-59 Identity = 137/446 (30.72%), Postives = 207/446 (46.41%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMPDNAI------NKEIGKLMVKCLYD--GCNHEEMLKDIGDHLNSCEYLTVVCE--KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANI-LKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQE-YYMKNDTIFLKIVV 1422
C C +L QT+CG R+C CI D L C C + + + I ++EI L V C + GC + L+ I DH+N C + V C KCK M K +P HL C R C C ++M L K + + +CP CP C + R E K++++ +R L +E ++ + ++ T+L + + L T+++ D M + +A++ L+ + NG IWK+ + K +A G +S+ S+PFYT FGYKM ++Y GDG+GK THLS+FF +M+G++D LL WPFK KVTL ++DQ D FKPDP S+ +++P E NIASG P F+S + L+ Y+K+DTIF+K+ V
Sbjct: 48 CEACRLVLCQPRQTECGHRFCYSCINDIL----SCPNPVCPADMEPLFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTELQK-----HKETVCPAFPVSCPNHC-----TSSSLPRSE----------------KLMSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLSALEQGGRASLE-------TQLNRHDDMLSVHEIR--------------LADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTV 442
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 157.147 bits (396), Expect = 5.590e-42 Identity = 134/501 (26.75%), Postives = 225/501 (44.91%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCS---------TIIST---MPDNAINKEIGKLMVKCLYDGCN-----------HEE----------------MLKDIGDHLN-SCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNI--CPKLVDKCPY---GCDIV---GAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEE---------FIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINY--RNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL--QEYYMKNDTIFLKIVV 1422
+ D KC C ++L +Q CG R+C C L +S + C +I+++ PDNA +EI L +CL GC+ HE + KD H + CE T+ C+ CK+ K + H + C K ++C +CG + K + + D+ C K CP+ GC V G ++ H + P V L ++ + S + + + ++ + + K++++LE + ++ ++E S+ E + +DQ +LS + + + + ++ Y +G+F+WK+ F + A G ++ S FY+ ++GYKM +++Y GDG G+ THLS+FF +M+ +D LL WPF KVTL +LDQ N+ D F+PD ST +Q+P E NIASG P F +L + Y+++DTIF+K +V
Sbjct: 24 MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFR-QLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKAHD-EICQKFPLQCKDCGKK-------KIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMV-LSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNR--EVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNR-EHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 511
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 157.147 bits (396), Expect = 6.011e-42 Identity = 134/501 (26.75%), Postives = 225/501 (44.91%), Query Frame = 1
Query: 103 LTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCS---------TIIST---MPDNAINKEIGKLMVKCLYDGCN-----------HEE----------------MLKDIGDHLN-SCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNI--CPKLVDKCPY---GCDIV---GAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEE---------FIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINY--RNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL--QEYYMKNDTIFLKIVV 1422
+ D KC C ++L +Q CG R+C C L +S + C +I+++ PDNA +EI L +CL GC+ HE + KD H + CE T+ C+ CK+ K + H + C K ++C +CG + K + + D+ C K CP+ GC V G ++ H + P V L ++ + S + + + ++ + + K++++LE + ++ ++E S+ E + +DQ +LS + + + + ++ Y +G+F+WK+ F + A G ++ S FY+ ++GYKM +++Y GDG G+ THLS+FF +M+ +D LL WPF KVTL +LDQ N+ D F+PD ST +Q+P E NIASG P F +L + Y+++DTIF+K +V
Sbjct: 31 MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFR-QLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKAHD-EICQKFPLQCKDCGKK-------KIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMV-LSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNR--EVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNR-EHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIV 518
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 153.68 bits (387), Expect = 8.070e-41 Identity = 121/488 (24.80%), Postives = 219/488 (44.88%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQ-TDCGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTM-PDNAINKEIGKLMVKCLY--DGCNHEEMLKDIGDHLNSCEYLTVVCE-KCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEI----------------------LMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIR--TLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKN----KTSDYSDTFKPDPRSTCYQQP------TEEYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
KRRF +C +CS+ + +Q + CG R+C C+++ L +C + + PD + ++I L ++C++ +GC +K + H ++C + + C +C +++ + LP+HL DC KR VKC CGS E +M+ L + CPK C Y + H+ C + PV+CP + G + + L++H+K + + + K + ++ L +++K+ + N + +I + + M + S+D GV IWK+ + A+ + S PFYT +GYK+ + + G+G G+ +HLSV+ ++ G++D+LL WPF KVT +ILDQ + K ++TF PDP +Q+P +E + G PKFIS ++++ Y++++ IF+K +
Sbjct: 13 KRRF--------QCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCP-NQCGTPNI-AREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSRQRQEILELRR---------------------EMEELSVSHD-------GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 152.91 bits (385), Expect = 8.148e-41 Identity = 121/488 (24.80%), Postives = 219/488 (44.88%), Query Frame = 1
Query: 82 KRRFPFNLTDNLKCVICSELLLNAMQ-TDCGCRYCQKCIEDHLVNSR-QCQTKGCSTIISTM-PDNAINKEIGKLMVKCLY--DGCNHEEMLKDIGDHLNSCEYLTVVC-EKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEI----------------------LMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIR--TLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKN----KTSDYSDTFKPDPRSTCYQQP------TEEYNIASGSPKFISFTQLQEY-YMKNDTIFLKIVV 1422
KRRF +C +CS+ + +Q + CG R+C C+++ L +C + + PD + ++I L ++C++ +GC +K + H ++C + + C +C +++ + LP+HL DC KR VKC CGS E +M+ L + CPK C Y + H+ C + PV+CP + G + + L++H+K + + + K + ++ L +++K+ + N + +I + + M + S+D GV IWK+ + A+ + S PFYT +GYK+ + + G+G G+ +HLSV+ ++ G++D+LL WPF KVT +ILDQ + K ++TF PDP +Q+P +E + G PKFIS ++++ Y++++ IF+K +
Sbjct: 13 KRRF--------QCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCP-NQCGTPNI-AREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMCNLVSRQRQEILELRR---------------------EMEELSVSHD-------GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASI 462
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039089.1 (SMESG000039089.1) HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0 Identity = 459/465 (98.71%), Postives = 461/465 (99.14%), Query Frame = 1
Query: 34 MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVLN 1428
MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQC TKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKR+VKCLNC SRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEF AHIRTLVEEFIKMKKEITSLETKLIESSKT KLELSNFQNEISTKISN+DQMSNSSLSLQSSSSLTLQSSASSMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVLN
Sbjct: 1 MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNSRQCSTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRVVKCLNCESRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFPAHIRTLVEEFIKMKKEITSLETKLIESSKTIKLELSNFQNEISTKISNIDQMSNSSLSLQSSSSLTLQSSASSMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVLN 465
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027153.1 (SMESG000027153.1) HSP 1 Score: 339.347 bits (869), Expect = 4.252e-112 Identity = 193/474 (40.72%), Postives = 268/474 (56.54%), Query Frame = 1
Query: 34 MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS-RQCQTK--GCSTIISTM-----PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCS-KVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFI--SFTQLQEYYMKNDTIFLKIVV 1422
MS + +P ++ Y + FP +L+D LKCV+C +L NA QT CGC+ C+ CI+ +L N + C +K C ++ M DNA NKEI L VKC + C+ E L+++ +H+NSCE+ + C KC+ ++ K +H C R +KC C M + L HL+ ++ C K CP CD+ V L H K C KK + CPF L C+ +T + L H+ E+ +H L+ + M+ I +L T +E+ K EL + + S + + + + I ++ + +RN FIWK F + +AE G ++SVTS+PFYT EFGYKM ++IYPAGDGVGK THLSVFF +MKG+FDDLL WPFK KVTL+I+DQ+ T +SDTFKPD RS CYQ+P +E NIASGSPKFI S Y KNDTI+LKI V
Sbjct: 1 MSQSLSQIPTILELY-EFNFP-SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNL-TDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTP------------IQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 459
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 303.138 bits (775), Expect = 3.733e-98 Identity = 172/451 (38.14%), Postives = 250/451 (55.43%), Query Frame = 1
Query: 100 NLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS-RQCQTKGCSTIISTMP-----DNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETK--LIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQ--EYYMKNDTIFLKIVV 1422
NL+ +LKC+ICS LL NA QT CGC+ C+ CI ++L + C K C + ++ DNA NKEI L + C + GC E + I H+ SCEY V C+ C+ + K H+ +C RI KC C M + L + HL+ + +C + V CP C +NL H + C+ + + TN + + T+ ++ + K +T LE + +I T + L+ +++ KI+ ++ ++ + I K+ND +RNG FIWK++ NAER R+S+TS+PFYT EFGYK+ +++YP+GDG+GK THLSVFF LMKG++DDLL WPF+ K+TL++LDQ+N T YSDTFKPDP+S C+Q+P + NIASGSPKF S + L Y KNDTI++KI V
Sbjct: 20 NLSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKECLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETCLNRKSD--------DQNDTNYHIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALE-----------------AERSNPVKIIAKTND----FRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTSEFGYKLCLRVYPSGDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITV 441
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039087.1 (SMESG000039087.1) HSP 1 Score: 297.36 bits (760), Expect = 1.556e-95 Identity = 163/444 (36.71%), Postives = 245/444 (55.18%), Query Frame = 1
Query: 121 CVICSELLLNAMQTDCGCRYCQKCIEDHLV-------NSRQCQTKGCSTIISTMPDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETKLIESSKTFK-LELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQLQEYYMKNDTIFLKIVVLN 1428
CVIC +L + +QT CGCRYC+ CI HL +S C+ + + D A ++ I L VKC C + L++I H N C ++ V C++C + L H +C KR C CG EIL H +++ ++C K + CPY C + ++L+ HRK C KP CP++E+GC + L+ HM+ H L++ M+ + L+++ + + K L +F + S +S + +S + +K + ++NG +IW ++ F LK A+ S+ S+PFYT EFGYK+ MKIYP GDG+GK THLSVFFT+M+G++D +LVWPF+NKVTL+ILDQ +K + YS+TF PD + C+ +PT ++N+ASGSPKFI+F+ L E Y+ N+ FLKI V N
Sbjct: 54 CVICKNVLTDPVQTSCGCRYCRSCIVKHLSFSSYCCNDSEDCRNELLELETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHKKIECEKRKEICQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVDLNKHMELNSINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKDYSRHLSQLQILSETKNQS------------------VKCTLDDTVFKNGNYIWHIKEFSVLKEEAKADRIASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSETFLPDIKLICFHKPTADFNVASGSPKFITFSNL-ENYIVNNGFFLKISVGN 478
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 270.396 bits (690), Expect = 1.175e-85 Identity = 164/451 (36.36%), Postives = 237/451 (52.55%), Query Frame = 1
Query: 100 NLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS-RQCQTKGCSTIISTMP-----DNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRIVKCLNCGSRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCSKVLTNQQLSDHMKTEFQAHIRTLVEEFIKMKKEITSLETK--LIESSKTFKLELSNFQNEISTKISNVDQMXXXXXXXXXXXXXXXXXXXXXMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFISFTQL--QEYYMKNDTIFLKIVV 1422
NL+ +LKC+ICS LL NA QT CGC+ C+ CI ++L + C K C + ++ DNA NKEI L + C + GC E + I H+ SCEY V C+ C+ + K H+ +C RI KC C M + L + HL+ + +C + V CP C +NL H + C+ + + TN + + T+ ++ + K +T LE + +I T + L+ +++ KI+ ++ ++ + I K+ND +RNG FIWK++ NAER R+S+TS+PFYT DG+GK THLSVFF LMKG++DDLL WPF+ K+TL++LDQ+N T YSDTFKPDP+S C+Q+P + NIASGSPKF S + L Y KNDTI++KI V
Sbjct: 20 NLSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKECLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETCLNRKSD--------DQNDTNYHIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALE-----------------AERSNPVKIIAKTND----FRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYT--------------SDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITV 427 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032110 ID=SMED30032110|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=1433bpback to top protein sequence of SMED30032110-orf-1 >SMED30032110-orf-1 ID=SMED30032110-orf-1|Name=SMED30032110-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=466bp MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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