Potassium voltage-gated channel protein Shaw

Overview
NamePotassium voltage-gated channel protein Shaw
Smed IDSMED30032095
Length (bp)1163
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Potassium voltage-gated channel protein Shaw (SMED30032095) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium voltage-gated channel protein Shaw (SMED30032095) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium voltage-gated channel protein Shaw (SMED30032095) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium voltage-gated channel protein Shaw (SMED30032095) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30032095

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30032095h1SMcG0013205 SmedASXL_013200SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30032095h1SMcG0013205 SmedASXL_013198SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30032095h1SMcG0013205 OX_Smed_1.0.02327ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
oocyteSMED30032095h1SMcG0013205 Contig44702uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
oocyteSMED30032095h1SMcG0013205 Contig44702newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
vitelline glandSMED30032095h1SMcG0013205 Contig44702uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
vitelline glandSMED30032095h1SMcG0013205 Contig44702newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Match: KCNC2 (potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234])

HSP 1 Score: 172.555 bits (436), Expect = 5.347e-48
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Match: KCNC2 (potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234])

HSP 1 Score: 172.94 bits (437), Expect = 7.977e-48
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Match: KCNC2 (potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234])

HSP 1 Score: 172.17 bits (435), Expect = 1.195e-47
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Match: KCNC2 (potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234])

HSP 1 Score: 172.17 bits (435), Expect = 1.783e-47
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Match: KCNC2 (potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234])

HSP 1 Score: 172.17 bits (435), Expect = 1.783e-47
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Match: shw-3 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A0A3B1DVP6])

HSP 1 Score: 238.039 bits (606), Expect = 6.623e-74
Identity = 135/279 (48.39%), Postives = 197/279 (70.61%), Query Frame = 1
Query:   52 SFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAK--------DGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAV 864
            S Q +  ISVFF+I ++I FCLK+ P L++  +      S N  + +++        D     P+  F+Y+E ICN +FTIE++ R  + PS F + ++P+N+IDI A  +FY+ L+     +       LE F+++R+ R+FKLT H SGLKIL+ TF+AS KEL+LL+FFL + +VVFA+ +YYAER++SN D QF+SI  GLWW+++TMTT+GYGD +P +  G L+G++CA+ GVLTI+LP+PVIVSNF+MFYSHTQAR+K+PK+RR VL ++ V
Sbjct:  167 SAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD----LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 441          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Match: shw-3 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A0A3B1DVP6])

HSP 1 Score: 238.424 bits (607), Expect = 9.041e-74
Identity = 135/279 (48.39%), Postives = 197/279 (70.61%), Query Frame = 1
Query:   52 SFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAK--------DGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAV 864
            S Q +  ISVFF+I ++I FCLK+ P L++  +      S N  + +++        D     P+  F+Y+E ICN +FTIE++ R  + PS F + ++P+N+IDI A  +FY+ L+     +       LE F+++R+ R+FKLT H SGLKIL+ TF+AS KEL+LL+FFL + +VVFA+ +YYAER++SN D QF+SI  GLWW+++TMTT+GYGD +P +  G L+G++CA+ GVLTI+LP+PVIVSNF+MFYSHTQAR+K+PK+RR VL ++ V
Sbjct:  185 SAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD----LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 459          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Match: shw-3 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A0A3B1DVP6])

HSP 1 Score: 238.039 bits (606), Expect = 1.118e-73
Identity = 135/279 (48.39%), Postives = 197/279 (70.61%), Query Frame = 1
Query:   52 SFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAK--------DGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAV 864
            S Q +  ISVFF+I ++I FCLK+ P L++  +      S N  + +++        D     P+  F+Y+E ICN +FTIE++ R  + PS F + ++P+N+IDI A  +FY+ L+     +       LE F+++R+ R+FKLT H SGLKIL+ TF+AS KEL+LL+FFL + +VVFA+ +YYAER++SN D QF+SI  GLWW+++TMTT+GYGD +P +  G L+G++CA+ GVLTI+LP+PVIVSNF+MFYSHTQAR+K+PK+RR VL ++ V
Sbjct:  188 SAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD----LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 462          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Match: egl-36 (Potassium voltage-gated channel protein egl-36 [Source:UniProtKB/Swiss-Prot;Acc:G5EFC3])

HSP 1 Score: 233.802 bits (595), Expect = 1.749e-71
Identity = 138/270 (51.11%), Postives = 193/270 (71.48%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++  ISV FI IS+ +FCLK+    ++  ++  NIT        + + V  +P   F  +E++CN +FT+ELI+R    PS   FFKSP+N+ID+ A  SFY   ++  +      ++ +E  +++R+FR+FKLT+H  GL+ILI TF+AS KELILL+FFL + IV+FAA +YYAE++++N + QF SI  GLWW++ TMTTVGYGD +P +  G LVG+LCAV GVLTI+LP+PVIVSNF+MFYSH QAR KLPK+RRRVLPVE +R
Sbjct:  204 KLIAGISVLFIFISIFSFCLKTHQSFRLPVLIGQNITMPGGVVQPSIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVEDEPKDV-VEFLSMIRIFRLFKLTQHHQGLQILIHTFRASAKELILLVFFLILGIVIFAALVYYAEKMEANPNNQFQSIPLGLWWAICTMTTVGYGDMTPHTSFGRLVGSLCAVMGVLTIALPVPVIVSNFAMFYSHNQARDKLPKRRRRVLPVEQIR 472          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Match: shw-1 (SHaW family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q8I4L3])

HSP 1 Score: 206.453 bits (524), Expect = 1.288e-61
Identity = 130/278 (46.76%), Postives = 187/278 (67.27%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI---VSVNITSSNTWAITAKDGVGPD-----PYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++  +SV FI+ S  +F LK+ P  ++ +I    S+ +     +    K  +G D     P+  F YV+LICN +FTIEL++R    PS   F +SP+ +ID+ +  +F+   +L+ +       + L+  +++ + R+FKLT+H SGLKILI TF+AS +EL LL+FF+ + IV+FAA +YYAER   N D QF SI  GLWWSL+T++TVG+GD  P++  GMLVG+LCA+ GVLTI+LP+PVIVSNFS  YSH+QARAKLPK+RRRVL    V+
Sbjct:  169 RVISSLSVAFILASTCSFILKTDPSFQIPDIDVFYSLRVVDEGGFKNYHKT-IGTDKPVTSPHPNFFYVDLICNIWFTIELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQTGSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAKLPKKRRRVLQAHEVK 445          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Match: Shaw (gene:FBgn0003386 transcript:FBtr0332184)

HSP 1 Score: 255.373 bits (651), Expect = 3.913e-80
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  174 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 443          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Match: Shaw (gene:FBgn0003386 transcript:FBtr0089274)

HSP 1 Score: 254.988 bits (650), Expect = 4.908e-80
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  174 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 443          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Match: Shaw (gene:FBgn0003386 transcript:FBtr0332185)

HSP 1 Score: 255.373 bits (651), Expect = 3.088e-79
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  174 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 443          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Match: Shaw (gene:FBgn0003386 transcript:FBtr0289989)

HSP 1 Score: 255.758 bits (652), Expect = 3.669e-79
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  189 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 458          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Match: Shaw (gene:FBgn0003386 transcript:FBtr0089275)

HSP 1 Score: 255.373 bits (651), Expect = 4.190e-79
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  174 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 443          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 161.384 bits (407), Expect = 1.775e-44
Identity = 109/266 (40.98%), Postives = 163/266 (61.28%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIY------------LETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +SV  I+IS++ FCL+++P LK      + +  ++T+    K  +  DP   F  VE +C  +F+ ELIVR FA PS  AFFK+ +N ID+ ++  +++ L       P                  L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +       Q
Sbjct:  167 VSVMVILISIVIFCLETLPELKEDPQGRLQVIGNSTFYY--KPNILTDP---FFVVETLCIIWFSFELIVRFFACPSKPAFFKNMMNTIDVVSIIPYFITLGTEMAEDPEGGKEAKGGGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEK--DSFFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGDEQAQ 424          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 161.384 bits (407), Expect = 1.775e-44
Identity = 109/266 (40.98%), Postives = 163/266 (61.28%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIY------------LETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +SV  I+IS++ FCL+++P LK      + +  ++T+    K  +  DP   F  VE +C  +F+ ELIVR FA PS  AFFK+ +N ID+ ++  +++ L       P                  L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +       Q
Sbjct:  167 VSVMVILISIVIFCLETLPELKEDPQGRLQVIGNSTFYY--KPNILTDP---FFVVETLCIIWFSFELIVRFFACPSKPAFFKNMMNTIDVVSIIPYFITLGTEMAEDPEGGKEAKGGGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEK--DSFFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGDEQAQ 424          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Match: kcna2b (potassium voltage-gated channel, shaker-related subfamily, member 2b [Source:ZFIN;Acc:ZDB-GENE-080204-89])

HSP 1 Score: 160.999 bits (406), Expect = 2.252e-44
Identity = 111/276 (40.22%), Postives = 169/276 (61.23%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLK--VANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN--------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPV 855
            +I+  ISV  I+IS+++FCL+++PV +    ++     T SN+  I+       DP   F  +E +C  +F+ E +VR FA PS   FF + +N+IDI A+  +++ L                      L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+QF+SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q   V  V
Sbjct:  163 RIIAIISVMVILISIVSFCLETLPVFRNEETDMHKAYRTDSNS-TISYTSTYFTDP---FFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTELAEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEP--DSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQYLNVTSV 431          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15])

HSP 1 Score: 160.999 bits (406), Expect = 2.632e-44
Identity = 108/263 (41.06%), Postives = 159/263 (60.46%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF---------XXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +SV  I+IS++ FCL+++P LK      + I  + T+    K  +  DP   F  +E +C  +F+ ELIVR FA PS  AFFK+ +N IDI A+  +                           L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   ++ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q
Sbjct:  169 VSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYY--KPSILADP---FFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQDGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEK--ESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQ 423          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15])

HSP 1 Score: 160.999 bits (406), Expect = 2.632e-44
Identity = 108/263 (41.06%), Postives = 159/263 (60.46%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF---------XXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +SV  I+IS++ FCL+++P LK      + I  + T+    K  +  DP   F  +E +C  +F+ ELIVR FA PS  AFFK+ +N IDI A+  +                           L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   ++ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q
Sbjct:  169 VSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYY--KPSILADP---FFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQDGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEK--ESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQ 423          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Match: KCNC2 (potassium channel, voltage gated Shaw related subfamily C, member 2 [Source:NCBI gene;Acc:100489216])

HSP 1 Score: 173.326 bits (438), Expect = 3.181e-48
Identity = 111/274 (40.51%), Postives = 172/274 (62.77%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERL-------DSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++        I++   T +N   + +   +  DP  A  YVE +C  +FT E +VR+   P    F ++ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+        ++  TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  192 RFIAFASLFFILVSITTFCLETHEAFNT--IINKTETVNNGTELISLIEIETDP--ALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Match: KCNC2 (potassium channel, voltage gated Shaw related subfamily C, member 2 [Source:NCBI gene;Acc:100489216])

HSP 1 Score: 172.555 bits (436), Expect = 8.245e-48
Identity = 111/274 (40.51%), Postives = 172/274 (62.77%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERL-------DSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++        I++   T +N   + +   +  DP  A  YVE +C  +FT E +VR+   P    F ++ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+        ++  TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  192 RFIAFASLFFILVSITTFCLETHEAFNT--IINKTETVNNGTELISLIEIETDP--ALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Match: KCNA1 (potassium channel, voltage gated shaker related subfamily A, member 1 [Source:NCBI gene;Acc:100492822])

HSP 1 Score: 167.933 bits (424), Expect = 8.095e-47
Identity = 111/266 (41.73%), Postives = 166/266 (62.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF--XXXXXXXXXNSPVRFN-----IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +I+  +SV  I+IS++ FCL+++P LK   I S  + +S  +    K  +  DP   F  VE +C  +F+ EL+VR FA PS   FFK+ +N IDI A+  +   L   +     P +         L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   ++ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q
Sbjct:  164 RIIAIVSVMVILISIVIFCLETLPELKDERIFSRRVNNSTVFY---KSNIFTDP---FFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITLGTEMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEED--ESHFASIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQ 420          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Match: fastkd3 (FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-5998409])

HSP 1 Score: 165.236 bits (417), Expect = 2.649e-46
Identity = 110/252 (43.65%), Postives = 157/252 (62.30%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF-----XXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFY 798
            +I+  ISV  I+IS++ FCL+++P  +    +S+     +  +   +     DP   F  VE IC  +F+ EL VR  A PS  AFFK  +N+ID  A+  +             +  P      L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE    + DT+F SI +  WW+++TMTTVGYGD SP ++ G LVG+LCA+ GVLTISLP+PVIVSNFS FY
Sbjct:  138 RIIAIISVMVILISIVIFCLETLPEFRDDRDLSL---PKDPLSGRPQKSPFEDP---FFIVETICICWFSFELSVRFIACPSKAAFFKDIMNMIDFVAIIPYFVALGTELARHKGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA--DHEDTKFTSIPEAFWWAVVTMTTVGYGDMSPETVGGKLVGSLCAIAGVLTISLPVPVIVSNFSYFY 381          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Match: fastkd3 (FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-5998409])

HSP 1 Score: 165.236 bits (417), Expect = 8.932e-46
Identity = 110/260 (42.31%), Postives = 158/260 (60.77%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITS-------SNTWAITAKDGVGPDPY-IAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF-----XXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFY 798
            +I+  ISV  I+IS++ FCL+++P  +    +S+ ++           W  +        P+   F  VE IC  +F+ EL VR  A PS  AFFK  +N+ID  A+  +             +  P      L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE    + DT+F SI +  WW+++TMTTVGYGD SP ++ G LVG+LCA+ GVLTISLP+PVIVSNFS FY
Sbjct:  164 RIIAIISVMVILISIVIFCLETLPEFRDDRDLSLPVSYILYCYPIVKLWPSSTHHFKEKSPFEDPFFIVETICICWFSFELSVRFIACPSKAAFFKDIMNMIDFVAIIPYFVALGTELARHKGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA--DHEDTKFTSIPEAFWWAVVTMTTVGYGDMSPETVGGKLVGSLCAIAGVLTISLPVPVIVSNFSYFY 421          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Match: Kcnc2 (potassium voltage gated channel, Shaw-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96668])

HSP 1 Score: 171.4 bits (433), Expect = 3.229e-47
Identity = 109/274 (39.78%), Postives = 173/274 (63.14%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++     +    +  + +  +  +  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  233 RFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSPVLQYE--IETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 502          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Match: Kcnc2 (potassium voltage gated channel, Shaw-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96668])

HSP 1 Score: 171.014 bits (432), Expect = 4.045e-47
Identity = 109/274 (39.78%), Postives = 173/274 (63.14%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++     +    +  + +  +  +  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  233 RFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSPVLQYE--IETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 502          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659])

HSP 1 Score: 162.54 bits (410), Expect = 6.833e-45
Identity = 110/277 (39.71%), Postives = 169/277 (61.01%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI------VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN--------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRV 846
            +I+  +SV  I+IS+++FCL+++P+ +  N       V+ +  S++T           DP   F  VE +C  +F+ E +VR FA PS   FF + +N+IDI A+  +++ L       P              L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+QF SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q  +V
Sbjct:  163 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFT-DP---FFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADER--DSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQYLQV 432          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659])

HSP 1 Score: 162.54 bits (410), Expect = 6.833e-45
Identity = 110/277 (39.71%), Postives = 169/277 (61.01%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI------VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN--------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRV 846
            +I+  +SV  I+IS+++FCL+++P+ +  N       V+ +  S++T           DP   F  VE +C  +F+ E +VR FA PS   FF + +N+IDI A+  +++ L       P              L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+QF SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q  +V
Sbjct:  163 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFT-DP---FFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADER--DSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQYLQV 432          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659])

HSP 1 Score: 162.54 bits (410), Expect = 6.833e-45
Identity = 110/277 (39.71%), Postives = 169/277 (61.01%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI------VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN--------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRV 846
            +I+  +SV  I+IS+++FCL+++P+ +  N       V+ +  S++T           DP   F  VE +C  +F+ E +VR FA PS   FF + +N+IDI A+  +++ L       P              L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  +   D+QF SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q  +V
Sbjct:  163 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFT-DP---FFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADER--DSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQYLQV 432          
BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Match: sp|P17972|KCNAW_DROME (Potassium voltage-gated channel protein Shaw OS=Drosophila melanogaster OX=7227 GN=Shaw PE=2 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 4.920e-79
Identity = 149/273 (54.58%), Postives = 198/273 (72.53%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVA---NIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            + +G +SVFFI IS+++FCLK+ P ++V    NI       SN W +   D    + +IAF Y+E +CN++FT E++VR  ++P+ + F KS +N+ID  A  SFY+ LVL    S +     LE F+++R+ R+FKLTRH SGLKILI TF+AS KEL LL+FFL + IV+FA+ +YYAER+  N    F SI  GLWW+L+TMTTVGYGD +P++  GM VGALCA+ GVLTI+LP+PVIVSNF+M+YSHTQARAKLPK+RRRVLPVE  R
Sbjct:  174 KTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFL---DKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 443          
BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Match: sp|G5EFC3|KCNAG_CAEEL (Potassium voltage-gated channel protein egl-36 OS=Caenorhabditis elegans OX=6239 GN=egl-36 PE=1 SV=1)

HSP 1 Score: 233.802 bits (595), Expect = 2.224e-70
Identity = 138/270 (51.11%), Postives = 193/270 (71.48%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++  ISV FI IS+ +FCLK+    ++  ++  NIT        + + V  +P   F  +E++CN +FT+ELI+R    PS   FFKSP+N+ID+ A  SFY   ++  +      ++ +E  +++R+FR+FKLT+H  GL+ILI TF+AS KELILL+FFL + IV+FAA +YYAE++++N + QF SI  GLWW++ TMTTVGYGD +P +  G LVG+LCAV GVLTI+LP+PVIVSNF+MFYSH QAR KLPK+RRRVLPVE +R
Sbjct:  204 KLIAGISVLFIFISIFSFCLKTHQSFRLPVLIGQNITMPGGVVQPSIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVEDEPKDV-VEFLSMIRIFRLFKLTQHHQGLQILIHTFRASAKELILLVFFLILGIVIFAALVYYAEKMEANPNNQFQSIPLGLWWAICTMTTVGYGDMTPHTSFGRLVGSLCAVMGVLTIALPVPVIVSNFAMFYSHNQARDKLPKRRRRVLPVEQIR 472          
BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Match: sp|P22462|KCNC2_RAT (Potassium voltage-gated channel subfamily C member 2 OS=Rattus norvegicus OX=10116 GN=Kcnc2 PE=1 SV=1)

HSP 1 Score: 171.785 bits (434), Expect = 1.476e-46
Identity = 109/274 (39.78%), Postives = 173/274 (63.14%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++     +    +  + +  +  +  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYE--IETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Match: sp|Q96PR1|KCNC2_HUMAN (Potassium voltage-gated channel subfamily C member 2 OS=Homo sapiens OX=9606 GN=KCNC2 PE=1 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 1.939e-46
Identity = 115/276 (41.67%), Postives = 175/276 (63.41%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSS--NTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++       NIV  N T    N  ++  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  229 RFIAFASLFFILVSITTFCLETHEAF---NIVK-NKTEPVINGTSVVLQYEIETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 498          
BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Match: sp|Q14B80|KCNC2_MOUSE (Potassium voltage-gated channel subfamily C member 2 OS=Mus musculus OX=10090 GN=Kcnc2 PE=1 SV=1)

HSP 1 Score: 171.014 bits (432), Expect = 2.830e-46
Identity = 109/274 (39.78%), Postives = 173/274 (63.14%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++     +    +  + +  +  +  +  +  DP  A  YVE +C  +FT E +VR+  +P+   F K+ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +  +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLP++R++ +P
Sbjct:  233 RFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSPVLQYE--IETDP--ALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP 502          
BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Match: A0A1I8HGQ1 (Ion_trans domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 9.888e-83
Identity = 159/276 (57.61%), Postives = 209/276 (75.72%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAIT-AKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI-YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++ +I+  +SVFFI+IS+++FCLK+ P L+V  I +V +   N   ++ A      +P+ AF Y+E +CNS+FT E++ R   TP  F F KSP+N+ID  A  SFY+ LVL  + S    +   LE F+++R+ R+FKLTRHI+GLKILI TF+AS KEL+LL+FFL VFIVVFAA IYYAER+  N +  F SI  GLWW+++TMTTVGYGD +P++  GM VGALCA+TGVLTI+LP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:   72 SVAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIITNVTVVVDNNDTMSYALYKTRSEPHSAFFYIECVCNSWFTFEIVTRFSVTPDKFEFLKSPVNIIDFIATLSFYMDLVLNQVLSEAEASYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIHYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMFVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 347          
BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Match: A0A1I8I9E9 (Ion_trans domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 268.855 bits (686), Expect = 1.429e-81
Identity = 160/276 (57.97%), Postives = 208/276 (75.36%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNIT-SSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIY-LETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++ +I+  +SVFFI+IS+++FCLK+ P L+V  I +V +   SN     A      +P+ AF Y+E +CNS+FT E++ R   TP  F F KSP+N+ID  A  SFY+ LVL  + S    +   LE F+++R+ R+FKLTRHI+GLKILI TF+AS KEL+LL+FFL VFIVVFAA IYYAER+  N +  F SI  GLWW+++TMTTVGYGD +P++  GM VGALCA+TGVLTI+LP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:   78 SVAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIITNVTVVVDSNDTMSYALYKTRSEPHSAFFYIECVCNSWFTFEIVTRFSVTPDKFEFLKSPVNIIDFIATLSFYMDLVLNQVLSEAEASYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIHYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMFVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 353          
BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Match: A0A1I8HHR2 (Ion_trans domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 4.768e-81
Identity = 159/279 (56.99%), Postives = 210/279 (75.27%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANI----VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIY-LETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++ +I+  +SVFFI+IS+++FCLK+ P L+V  I    V ++   S ++ +        +P+ AFLY+E +CNS+FT E+I R   TP    F KSP+N+ID  A  SFY+ +VL  + S    +   LE F+++R+ R+FKLTRHI+GLKILI TF+AS KEL+LL+FFL VFIVVFAA IYYAER+  N +  F SI  GLWW+++TMTTVGYGD +P++  GMLVGALCA+TGVLTI+LP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:   66 SMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGSTSFVLHKHRS---EPHTAFLYIECVCNSWFTFEIITRFAVTPDKREFLKSPVNIIDFIATLSFYMDMVLNQVLSEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 341          
BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Match: A0A267FE93 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007473g1 PE=3 SV=1)

HSP 1 Score: 266.929 bits (681), Expect = 7.754e-81
Identity = 160/276 (57.97%), Postives = 208/276 (75.36%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNIT-SSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIY-LETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++ +I+  +SVFFI+IS+++FCLK+ P L+V  I +V +   SN     A      +P+ AF Y+E +CNS+FT E++ R   TP  F F KSP+N+ID  A  SFY+ LVL  + S    +   LE F+++R+ R+FKLTRHI+GLKILI TF+AS KEL+LL+FFL VFIVVFAA IYYAER+  N +  F SI  GLWW+++TMTTVGYGD +P++  GM VGALCA+TGVLTI+LP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:  166 SVAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIITNVTVVVDSNDTMSYALYKTRSEPHSAFFYIECVCNSWFTFEIVTRFSVTPDKFEFLKSPVNIIDFIATLSFYMDLVLNQVLSEAEASYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIHYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMFVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 441          
BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Match: A0A1I8G894 (Ion_trans domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 265.003 bits (676), Expect = 7.805e-81
Identity = 161/275 (58.55%), Postives = 207/275 (75.27%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI----VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXX-XXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +I+  +SVFFI+IS+++FCLK+ P L+V  I    V +++  + ++A         +P+ AF +VE +CNS+FT E++ R   TPS   F KSP+N+ID  A  SFY+ L L   LN+       LE F+++R+ R+FKLTRHISGLKILI TF+AS KEL+LL+FFL VFIVVFAA IYYAER+  N D  F SI  GLWW+++TMTTVGYGD +P++  GMLVGALCA+TGVLTI+LP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:   76 KIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVVLDLLGNQSFAFYKHRS---EPHQAFFFVECVCNSWFTFEIVTRFAVTPSKLEFLKSPVNIIDFIATLSFYMDLALNSALNADEASYEVLEFFSIIRIMRLFKLTRHISGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPDNSFDSIPIGLWWAIVTMTTVGYGDMTPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVR 347          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:103039047])

HSP 1 Score: 164.851 bits (416), Expect = 7.187e-46
Identity = 111/263 (42.21%), Postives = 167/263 (63.50%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN---------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFY---SHTQARAKL 825
            +SV  I++S++ FCL+++P LK      + I  ++T+    K  +  DP   F  VE +C  +F+ ELIVR  A PS  AFFK  +N ID+ A+  +++ L       P   +           L    +VR+FRIFKL+RH  GL+IL LT +ASM+EL LL+FFLF+ +++F++ +Y+AE  ++  D+ F SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY   +  + +AKL
Sbjct:  169 VSVTVILVSIVIFCLETLPQLKENPEGHIQIIGNSTFYY--KPSLLTDP---FFIVETLCIIWFSFELIVRFLACPSKAAFFKDMMNTIDVVAIIPYFITLGTELAEDPNNKDGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGLTLKASMRELGLLVFFLFIGVILFSSAVYFAEAEEA--DSYFGSIPDAFWWAVVSMTTVGYGDMVPVTIGGKVVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAKL 424          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Match: kcna2b (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:103039676])

HSP 1 Score: 162.155 bits (409), Expect = 8.691e-45
Identity = 109/275 (39.64%), Postives = 170/275 (61.82%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANI-VSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN--------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPV 855
            +I+  ISV  I+IS+++FCL+++P+ +  +I +      ++    +       DP   F  +E +C  +F+ E +VR FA PS   FF + +N+IDI A+  +++ L      SP              L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  ++  D+QF+SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q   V  V
Sbjct:  162 RIIAIISVMVILISIVSFCLETLPIFRNDDIDMRKTYPGNSNSTTSYTSTYFTDP---FFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTELAESPEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEA--DSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQYLNVTSV 430          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Match: ENSAMXT00000014366.2 (potassium voltage-gated channel subfamily A member 3-like [Source:NCBI gene;Acc:103034012])

HSP 1 Score: 159.073 bits (401), Expect = 6.658e-44
Identity = 103/253 (40.71%), Postives = 154/253 (60.87%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGP------DPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFY 798
            +I+  ISV  I++S++ FCL+++P  +    +          A  +     P      DP   F  VE IC  +F  EL++R  ++P+   F K  +N+ID+ A+  +++ L      S     I +    +VR+FRIFKL+RH  GL+IL  TFQASM+EL LL+FFL + +++F++ IY+AE    +  + F SI    WW+++TMTTVGYGD  P ++ G +VG++CA+ GVLTISLP+PVIVSNFS FY
Sbjct:  175 RIIAIISVMVIMLSILIFCLETLPEFRAEKELREKERDEQYMAGNSTGSFSPSFTLFQDP---FFIVETICICWFLFELVMRFLSSPNKLHFCKDVMNVIDLMAILPYFVTLGTELTRSKSSLAI-VRVIRLVRVFRIFKLSRHSKGLQILGQTFQASMRELGLLIFFLLIGVILFSSAIYFAE--SDHEGSSFESIPHAFWWAVVTMTTVGYGDMYPETVWGKMVGSMCAIAGVLTISLPVPVIVSNFSYFY 421          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Match: kcnc2 (potassium voltage-gated channel, Shaw-related subfamily, member 2 [Source:ZFIN;Acc:ZDB-GENE-070410-118])

HSP 1 Score: 158.303 bits (399), Expect = 6.117e-43
Identity = 105/261 (40.23%), Postives = 161/261 (61.69%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQA 813
            + + + S+FFI++S+  FCL++          +  + + +   ++ +  +  DP  A  YVE +C  +FT E +VR+  +P    F KS +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS+ E  LL+ FL + +++FA  IYYAER+ +N +       T F +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A
Sbjct:  195 RFVAFASLFFIMVSITTFCLETHEAFNTIINKTDALRNDSLLEVSPQYEIETDP--ALTYVEGVCVLWFTFEFLVRVTFSPDKLEFVKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFFLLIIFLALGVLIFATMIYYAERIGANPNDPTASDHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 453          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Match: kcnc2 (potassium voltage-gated channel, Shaw-related subfamily, member 2 [Source:ZFIN;Acc:ZDB-GENE-070410-118])

HSP 1 Score: 157.918 bits (398), Expect = 6.941e-43
Identity = 105/261 (40.23%), Postives = 161/261 (61.69%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQA 813
            + + + S+FFI++S+  FCL++          +  + + +   ++ +  +  DP  A  YVE +C  +FT E +VR+  +P    F KS +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS+ E  LL+ FL + +++FA  IYYAER+ +N +       T F +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A
Sbjct:  180 RFVAFASLFFIMVSITTFCLETHEAFNTIINKTDALRNDSLLEVSPQYEIETDP--ALTYVEGVCVLWFTFEFLVRVTFSPDKLEFVKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFFLLIIFLALGVLIFATMIYYAERIGANPNDPTASDHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 438          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007589.1 (pep scaffold:Pmarinus_7.0:GL482983:7539:12291:-1 gene:ENSPMAG00000006849.1 transcript:ENSPMAT00000007589.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 179.874 bits (455), Expect = 2.599e-54
Identity = 119/274 (43.43%), Postives = 173/274 (63.14%), Query Frame = 1
Query:   52 SFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDS--NID---TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            S Q + YIS+FFI++S+  FCL++      A+  +V   S      T  +   P    A +Y+E +C  +FTIE +VR+  +P+   F K+ +N+ID+ A+  FYL + L  L S     +  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAERL +   ID   T F SI  G WW+++TMTT+GYGD  P++  GMLVGALCA++GVLTI++P+PVIV+NF M+YS   A+ KLPK++   +P
Sbjct:    2 SAQYVAYISLFFILVSITTFCLETHEAFTNASGTTVVPLSPMPTESTEYE-TAP----ALMYIEGMCVVWFTIEFMVRILTSPNKREFMKNKLNIIDLIAILPFYLEVGLSNLKSKGAREVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLKASTNEFLLLIIFLALGVLIFATMIYYAERLGAKPGIDEDKTHFTSIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALSGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNSYMP 270          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001869.1 (pep scaffold:Pmarinus_7.0:GL480351:152:3521:-1 gene:ENSPMAG00000001700.1 transcript:ENSPMAT00000001869.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.525 bits (384), Expect = 2.942e-43
Identity = 98/265 (36.98%), Postives = 157/265 (59.25%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPV----RFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRR 840
            ++L  IS+ FI++S IA  L ++P L+  +                   V  +P +A  +VE +C ++FT E ++R  ++P+ + FFK  +N+ID+ A+  +Y+ + L   N  V         ++ F ++R+ RI KL RH +GL+ L  T + S  EL LL+ FL + I++F++ +++AE+ +   DT+F SI    WW+ ITMTTVGYGD  P++L G +VG LC + GVL I+LPIP+IV+NFS FY   + + K  K+R 
Sbjct:    2 KVLAIISILFIVLSTIALSLNTLPDLQETD---------------EYGNVMDNPSLA--HVEAVCIAWFTTEYMLRFLSSPNKWKFFKGALNVIDLLAILPYYITIFLTESNHSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDED--DTKFRSIPASFWWATITMTTVGYGDIYPQTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAVKRRE 247          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Match: kcnc1a (potassium voltage-gated channel, Shaw-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-061220-10])

HSP 1 Score: 157.918 bits (398), Expect = 3.030e-43
Identity = 109/261 (41.76%), Postives = 159/261 (60.92%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNS-PVRFNI-YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQA 813
            +I+   S+ FI+IS+  FCL++          + N T +N         V  DP +  +YVE +C ++F+ E +VR+   P    F K+ +N+ID  A+  FYL + L  L S P R  + +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  I+YAER  +N +       T F +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NFSM+YS   A
Sbjct:  207 RIVALASLLFILISITTFCLETHEAFNTVLNKTENYTINNVTTQKVYVDVETDPVL--MYVEGVCVAWFSFEFLVRIICCPDKKVFIKNYLNVIDFVAILPFYLEVGLSSLTSKPARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIFYAERFGANPNDPTASDHTSFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFSMYYSLAMA 465          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005395.1 (pep scaffold:Pmarinus_7.0:GL482646:8602:10978:-1 gene:ENSPMAG00000004908.1 transcript:ENSPMAT00000005395.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 154.836 bits (390), Expect = 3.373e-43
Identity = 116/359 (32.31%), Postives = 189/359 (52.65%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVG---PDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPV----RFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVRXXXXXXXXXXXXXXNNQITDVDFR-------NKKSEMDEISKPKINGSNIHKGHRPSIQMTGKVFPKSFQKLEVSQNDDESP 1092
            Q+L  IS+ FI++S IA  L ++P L+                   KD  G    +P +A  +VE +C ++FT E ++R  ++P+ + FFK  +N+ID+ A+  +Y+ + L   N  V         ++ F ++R+ RI KL RH +GL+ L  T + S  EL LL+ FL + I++F++ +++AE+ +   DT+F SI    WW+ ITMTTVGYGD  P++L G +VG LC + GVL I+LPIP+IV+NFS FY   Q R +   +RR  L             +     +  +++D+          +K+ E D + + + +      G R    +T  V   S + LE+  ++  SP
Sbjct:    1 QMLAIISILFIVLSTIALSLNTLPELQ------------------HKDEYGHFTDNPSLA--HVEAVCIAWFTTEYMLRFLSSPNKWKFFKGALNVIDLLAILPYYITIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEQ--DTKFKSIPASFWWATITMTTVGYGDIYPQTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKE-QKRQEKAVKRREALERAKRNGSIVSMNSKEACARGLELSDMSQHHGSSIEVHKEKEADALQQQQCSPGRWKWGRR---SVTSLVETGSVKSLELKTSESPSP 333          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 153.295 bits (386), Expect = 4.179e-42
Identity = 105/239 (43.93%), Postives = 152/239 (63.60%), Query Frame = 1
Query:  109 FCLKSVPVLKV-ANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFN-------IYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYS 801
            FCL+++P  +  A++  V+  ++ T        V  DP   F  +E IC  +F+ EL+VR  A PS   F K+ +N+IDI A+  +++ L           N         L    +VR+FRIFKL+RH  GL+IL  T  ASM+EL LL+FFLF+ +++F++ +++AE +DS   T+F SI D  WWSL+TMTTVGYGD SP+++ G +VG+LCA+ GVLT+SLP+PVIVSNF+ FY 
Sbjct:  185 FCLETLPEFRDDADLYKVSYYTNGTHYFYHN--VFADP---FFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITLGTEMAEQTGSANGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGHTLHASMRELGLLIFFLFIGVILFSSAVFFAE-VDSK-KTEFQSIPDAFWWSLVTMTTVGYGDMSPKTVGGKIVGSLCAIAGVLTVSLPVPVIVSNFNYFYQ 416          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Match: EDO39804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8W8])

HSP 1 Score: 167.162 bits (422), Expect = 8.818e-48
Identity = 113/265 (42.64%), Postives = 166/265 (62.64%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRR 840
            +I  Q+L +I++F II S+  FCL++VP  K  N                K   G   YI    +E +C ++FT+E + RL   P   +FFK P+N ID+ A+  FYL L++   N   +  + L    ++R+FRIFKL+RH  GL+IL  T ++S  EL LL+FFL + +V+F++ I+YAE+      T F +I    WW+++TMTT+GYGD  P +  G +VG+LCAV GVL I+LP+PVIVSNFS++YSH +AR KLP+++R
Sbjct:  179 SIPAQVLAFITMFLIISSVCLFCLETVP--KFDN---------------PKTSEGFVLYI----LEAVCVAWFTLEFLFRLIFCPDKLSFFKKPMNWIDLGAILPFYLTLIVRESN--FKTIVVLRVVRLIRVFRIFKLSRHSYGLQILGHTLRSSCSELFLLVFFLTIGVVIFSSVIFYAEK--DTKGTHFTTIPHTFWWAVVTMTTLGYGDMVPITWQGQIVGSLCAVCGVLMIALPVPVIVSNFSLYYSHAKARMKLPRRKR 418          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Match: EDO38237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ4])

HSP 1 Score: 153.68 bits (387), Expect = 8.924e-43
Identity = 93/262 (35.50%), Postives = 153/262 (58.40%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRR 843
            +I  Y S  FI +S+  FC  ++P ++  NI+             +++G+         ++E+ C+ +F+ EL +RL + PS   F +  +N ID  A+  FY+ +           N  +  F V+R+ R+F+  +   GL+I+I T +AS  EL+LL+  + + +V+F++ +YY E +      QF S+ +  WW LITMTTVGYGD +P++ PG ++G  CA+ GVL ++LPI VI SNF+++Y+H QAR KLP ++RR
Sbjct:  176 KIFSYTSCLFIALSIATFCATTMPAIRKNNIMG------------SREGLD--------HIEMFCSIFFSFELFMRLISCPSKLHFCRGIMNWIDFVAIIPFYVNIFYP--------NPIVRMFLVIRIMRLFRFIKLSYGLQIMIQTLKASSHELVLLLLMVLIPMVMFSSIVYYVEVIIEGRGAQFTSVPESFWWCLITMTTVGYGDMTPQTWPGKIIGGACAICGVLIVALPISVIGSNFNLYYAHAQARLKLPVKQRR 409          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45])

HSP 1 Score: 152.14 bits (383), Expect = 2.423e-42
Identity = 101/256 (39.45%), Postives = 163/256 (63.67%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVN-----ITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQ 810
            ++L   SV  I+IS++ FC++++P  +       N     +  +N+   TA      +   A+L +E++C ++FT+E +VRL ++P    F +S +N+ID+ A+  +Y+ L +  L   +     L    +VR+FRIFKL+RH  GL++L  T +AS +EL +L+FFL + +V+F++ +YYAE  +    ++F SI D  WW+++TMTTVGYGD  P +  G LVG++CA++GVLTI+LP+PVIVSNF+ FY   Q
Sbjct:  131 RVLAVWSVSVILISIVVFCIETLPTFRCKTSPDGNGCPKLLPGTNS---TADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSPQKLLFVRSFLNVIDLMAILPYYITLPMKDLR--ITSLAVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAE--EEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYFYKREQ 379          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Match: SHAK6 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM4])

HSP 1 Score: 150.599 bits (379), Expect = 6.423e-42
Identity = 102/245 (41.63%), Postives = 153/245 (62.45%), Query Frame = 1
Query:   76 SVFFIIISLIAFCLKSVPVL--KVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSH 804
            SV  I++S++ FC++++P    +   ++  NIT +       K          F  +E  C ++FT+E  +R   +P    F  S +NLID+ A+  F++ L +    S     I L    +VR+FRIFKL+R+  GL+IL  T +AS++EL LL FFL V +++F++ +YYAE  + N DT+F+SI    WWS+ITMTTVGYGD +P++L G LVG  CA++GVL I+LP+PVIVSNF+ +YS 
Sbjct:  137 SVAVIVLSIVLFCVETLPQFQRRPKEVLRNNITETIMIDNPKKS--------VFFAIESFCIAWFTLEYFIRFLCSPDKCKFVVSVLNLIDLVAILPFFITLPMTEPTSVSSLAI-LRCVRLVRVFRIFKLSRYSRGLQILGHTLKASLRELGLLFFFLCVGVILFSSAVYYAE-YNYNRDTEFLSIPHSFWWSIITMTTVGYGDMAPKTLGGKLVGCFCAISGVLAIALPVPVIVSNFAYYYSR 371          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Match: EDO42724 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0S6])

HSP 1 Score: 147.902 bits (372), Expect = 1.099e-40
Identity = 111/264 (42.05%), Postives = 162/264 (61.36%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYV--ELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRR 843
            +++ Y ++  I++S+  FCL+S+                             + Y+  L V  E IC  +FT+EL+VR    P+   FFK  +N ID  A+  FY+ L     N+ +     L    ++R+FRIFKL+RH SGL+IL  T +AS +EL+LL+FFL + +V+FA+ I+Y E+      T+F+ I    WW+++TMTTVGYGD +P+S  G  +G+LCAV GVLTI+LP+PVIV+NFS++YSH QAR KLPK+RRR
Sbjct:  170 KVIAYTTLTLILVSVGIFCLESMEKFS-------------------------EKYLKDLLVILEGICVVWFTLELMVRFVFCPAKCEFFKKIMNWIDFLAIVPFYVSLGFNNNNNDID---ALMIIRLIRIFRIFKLSRHSSGLQILGHTLRASFRELLLLIFFLLIGVVLFASLIFYCEKKIPG--TKFVDIPSSFWWAVVTMTTVGYGDMAPQSPSGKFIGSLCAVCGVLTIALPVPVIVNNFSLYYSHAQARLKLPKKRRR 403          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Match: kcnc1b (potassium voltage-gated channel subfamily C member 1 [Source:NCBI gene;Acc:101165633])

HSP 1 Score: 173.711 bits (439), Expect = 1.874e-48
Identity = 115/274 (41.97%), Postives = 175/274 (63.87%), Query Frame = 1
Query:   76 SVFFIIISLIAFCLKSV----PVLKVANIVSV-NITSSNTWAITAKDGVGPDPYIAFL-YVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            S+FFI++S+  FCL++     P++    +  + NIT+ NT+  T           A+L Y+E +C  +FT E ++R+   P+ F F ++ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +N +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLPK++ R +P
Sbjct:  194 SLFFILVSITTFCLETHEAFNPIVNRTYVEHLDNITTENTYQETET--------AAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP 459          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Match: kcnc1b (potassium voltage-gated channel subfamily C member 1 [Source:NCBI gene;Acc:101165633])

HSP 1 Score: 173.326 bits (438), Expect = 2.558e-48
Identity = 115/274 (41.97%), Postives = 175/274 (63.87%), Query Frame = 1
Query:   76 SVFFIIISLIAFCLKSV----PVLKVANIVSV-NITSSNTWAITAKDGVGPDPYIAFL-YVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            S+FFI++S+  FCL++     P++    +  + NIT+ NT+  T           A+L Y+E +C  +FT E ++R+   P+ F F ++ +N+ID  A+  FYL + L  L+S    ++  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ +N +       TQF +I  G WW+++TMTT+GYGD  P++  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLPK++ R +P
Sbjct:  194 SLFFILVSITTFCLETHEAFNPIVNRTYVEHLDNITTENTYQETET--------AAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP 459          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Match: ENSORLT00000045623.1 (potassium voltage-gated channel subfamily C member 1-like [Source:NCBI gene;Acc:101168545])

HSP 1 Score: 171.014 bits (432), Expect = 2.541e-47
Identity = 114/279 (40.86%), Postives = 167/279 (59.86%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVL-----KVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNID-------TQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLP 852
            + + + S+FFI++S+  FCL++         K  N+   N T          DG          YVE +C  +FTIE++ R+   P    FF+S +N+ID  A+  FYL + L  L+S    +I  +L     VR+ RIFKLTRH  GL++L  T +AS  E +LL+ FL + +++FA  IYYAER+ ++ +       T F +I  G WW+++TMTT+GYGD  P +  GMLVGALCA+ GVLTI++P+PVIV+NF M+YS   A+ KLPK+R + +P
Sbjct:  181 RYVAFASLFFILLSISTFCLETHEAFNTIYNKTENVTVGNFTHEEIVYEVVTDGW-------LTYVEGVCVIWFTIEVMARVIFCPDKAEFFRSALNIIDFVAIVPFYLEVALSGLSSKTAKDILSFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPNDPTAAAHTTFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRNKHIP 452          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:101161480])

HSP 1 Score: 163.696 bits (413), Expect = 2.256e-45
Identity = 110/262 (41.98%), Postives = 164/262 (62.60%), Query Frame = 1
Query:   73 ISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNI--------YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQ 834
            +SV  I+IS++ FCL+++P LKV +        ++T+    K  +  DP   F  +E +C  +F+ ELIVR  A PS  AFFK+ +N IDI A+  +++ L       P +  +         L    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ +Y+AE  D      F+SI D  WW++++MTTVGYGD  P ++ G +VG+LCA+ GVLTI+LP+PVIVSNF+ FY H +   +   Q
Sbjct:  169 VSVMVILISIVIFCLETLPQLKVDSTGHFYSVGNSTFYY--KPNIFTDP---FFVIETLCIIWFSFELIVRFLACPSKPAFFKNMMNTIDIVAIIPYFITLGTELAEDPNKEAVGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVEDGG---SFVSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEGEEQAQ 421          
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Match: ENSORLT00000043885.1 (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:101160112])

HSP 1 Score: 162.54 bits (410), Expect = 9.244e-45
Identity = 109/259 (42.08%), Postives = 163/259 (62.93%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSF----XXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAK 822
            +I+  ISV  I++S++ FCL+++P LK       + + + +   ++   +  DP   F  VE IC  +F+ EL++R  + PS   FFK  +N+ID  A+  +       L     +SP      +    +VR+FRIFKL+RH  GL+IL  T +ASM+EL LL+FFLF+ +++F++ IY+AE  D N  T F+SI  G WW+++TMTTVGYGD  P ++ G +VG++CA+ GVLTISLP+PVIVSNFS FY H +   +
Sbjct:  199 RIIAIISVMVIVLSILIFCLETIPALKADKEDFHSHSKNGSENGSSLPSIFHDP---FFIVETICICWFSFELVMRFASAPSKMRFFKDIMNIIDFSAILPYFVTLGTELAKTNDSSPGTSLAIIRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVILFSSAIYFAE-ADHNT-TDFVSIPHGFWWAVVTMTTVGYGDMYPATVWGKMVGSMCAIAGVLTISLPVPVIVSNFSYFY-HRETECE 451          
BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Match: SMESG000013590.1 (SMESG000013590.1)

HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0
Identity = 357/358 (99.72%), Postives = 358/358 (100.00%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVRXXXXXXXXXXXXXXNNQITDVDFRNKKSEMDEISKPKINGSNIHKGHRPSIQMTGKVFPKSFQKLEVSQNDDESPVTIARKINSMDTK 1131
            +ILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFYLYLVLYYLNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELILLMFFLFVFIVVFAAFIYYAERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVRPKGKGPPTMGPPRKNNQITDVDFRNKKSEMDEISKPKINGSNIHKGHRPSIQMTGKVFPKSFQKLEVSQNDDESPVTIARKINSMDTK
Sbjct:  170 KILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFYLYLVLYYLNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELILLMFFLFVFIVVFAAFIYYAERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVRPKGKGPPTMGPPRKNNQITDVDFRNKKSEMDEISKPKINGSNIHKGHRPSIQMTGKVFPKSFQKLEVSQNDDESPVTIARKINSMDTK 527          
BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Match: SMESG000039493.1 (SMESG000039493.1)

HSP 1 Score: 272.322 bits (695), Expect = 2.078e-86
Identity = 154/271 (56.83%), Postives = 207/271 (76.38%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNIT-SSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++   S+ FI++S+I+FCLKS+P  ++ NI  VN T + N   +       P  + AF+Y++ +CN +FT EL++RL  T  +  F +SP+N+ID+FAL SFYL    Y    P+  N   + F+V+RL R+FKLTR+ISGLKIL++TF+AS KEL LL+FFL VFIV+FAA +YYAER +SN + +F SII GLWW++ITMTTVG+GDY P +  GML+GALCAVTGVLT+SLP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLP+E++R
Sbjct:  168 KVITGFSITFIVVSIISFCLKSIPGFQIQNISLVNATFTPNETTVNYFTSAAPIAHRAFIYIDAVCNVFFTFELLIRLAVTTRLSNFIQSPLNIIDLFALISFYLEFSFYVSVHPINNNAVFQFFSVIRLMRVFKLTRYISGLKILVVTFKASAKELSLLVFFLIVFIVIFAALVYYAERFNSNPENKFDSIIIGLWWAIITMTTVGFGDYVPVTNSGMLIGALCAVTGVLTVSLPVPVIVSNFSMFYSHTQARSKLPKERRRVLPIESIR 438          
BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Match: SMESG000059794.1 (SMESG000059794.1)

HSP 1 Score: 270.781 bits (691), Expect = 9.033e-86
Identity = 158/279 (56.63%), Postives = 210/279 (75.27%), Query Frame = 1
Query:   46 NISFQILGYISVFFIIISLIAFCLKSVPVLKVANI----VSVNIT-SSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            ++S +IL  +SV FII+S+  FC+K+VP +          S+++T SS+ W++   D +      +   ++ +CN YFT+ELI RLF +P+I  F +SP+N+ID  +L SFY        +S +++N+Y+E  +++RL R+FKLTRHISGLKILILTF+AS KEL LL+FFL VFIV+FAA IYYAER   +   +F SII GLWW+++TMTTVGYGD++P S+ GM+VGALCAVTGVLTISLP+PVIVSNFS FYSHTQAR+KLPK+RRRVLPVEAVR
Sbjct:  166 SLSAKILSSLSVIFIILSIAIFCIKTVPGINTVTFKNYSYSIDLTNSSSEWSL---DPLNIQKSQSIFIIDALCNIYFTVELITRLFISPNIVTFIQSPLNIIDTLSLMSFYFDFAFASSSSQLQYNVYIEFLSIIRLMRVFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIVLFAALIYYAERFKYDSLNKFDSIIVGLWWAIVTMTTVGYGDFAPTSVAGMIVGALCAVTGVLTISLPVPVIVSNFSTFYSHTQARSKLPKKRRRVLPVEAVR 441          
BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Match: SMESG000039493.1 (SMESG000039493.1)

HSP 1 Score: 272.322 bits (695), Expect = 1.743e-85
Identity = 154/271 (56.83%), Postives = 207/271 (76.38%), Query Frame = 1
Query:   58 QILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNIT-SSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXXNSPVRFNIYLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            +++   S+ FI++S+I+FCLKS+P  ++ NI  VN T + N   +       P  + AF+Y++ +CN +FT EL++RL  T  +  F +SP+N+ID+FAL SFYL    Y    P+  N   + F+V+RL R+FKLTR+ISGLKIL++TF+AS KEL LL+FFL VFIV+FAA +YYAER +SN + +F SII GLWW++ITMTTVG+GDY P +  GML+GALCAVTGVLT+SLP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLP+E++R
Sbjct:  263 KVITGFSITFIVVSIISFCLKSIPGFQIQNISLVNATFTPNETTVNYFTSAAPIAHRAFIYIDAVCNVFFTFELLIRLAVTTRLSNFIQSPLNIIDLFALISFYLEFSFYVSVHPINNNAVFQFFSVIRLMRVFKLTRYISGLKILVVTFKASAKELSLLVFFLIVFIVIFAALVYYAERFNSNPENKFDSIIIGLWWAIITMTTVGFGDYVPVTNSGMLIGALCAVTGVLTVSLPVPVIVSNFSMFYSHTQARSKLPKERRRVLPIESIR 533          
BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Match: SMESG000071446.1 (SMESG000071446.1)

HSP 1 Score: 267.7 bits (683), Expect = 5.480e-84
Identity = 156/274 (56.93%), Postives = 208/274 (75.91%), Query Frame = 1
Query:   52 SFQILGYISVFFIIISLIAFCLKSVPVLKVANIVSVNITSSNTWAITAKDGVGPDPYIAFLYVELICNSYFTIELIVRLFATPSIFAFFKSPINLIDIFALFSFXXXXXXXXX-NSPVRFNI-YLETFNVVRLFRIFKLTRHISGLKILILTFQASMKELXXXXXXXXXXXXXXXXXXXXXERLDSNIDTQFMSIIDGLWWSLITMTTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQARAKLPKQRRRVLPVEAVR 867
            S +I+  I+VFFI+IS+++FCLK+    ++ N+ +++++ +++WAI+      P  +  F YVE ICN +FTIE+I+R    PS F F KSP+N+ID  AL SFYL ++L  +  S    N+  LE F+++R+ R+FKLTRHI+GL IL+ TF+AS+KEL+LL+FFL VFIV+FAA +YYAER   N    F SI  GLWW+++TMTTVGYGD  P +  GM VGALCA+TGVLTISLP+PVIVSNFSMFYSHTQAR+KLPK+RRRVLPVE+VR
Sbjct:  167 SSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKS---SPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR 437          
The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNC25.347e-4841.67potassium voltage-gated channel subfamily C member... [more]
KCNC27.977e-4841.67potassium voltage-gated channel subfamily C member... [more]
KCNC21.195e-4741.67potassium voltage-gated channel subfamily C member... [more]
KCNC21.783e-4741.67potassium voltage-gated channel subfamily C member... [more]
KCNC21.783e-4741.67potassium voltage-gated channel subfamily C member... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shw-36.623e-7448.39SHaW family of potassium channels [Source:UniProt... [more]
shw-39.041e-7448.39SHaW family of potassium channels [Source:UniProt... [more]
shw-31.118e-7348.39SHaW family of potassium channels [Source:UniProt... [more]
egl-361.749e-7151.11Potassium voltage-gated channel protein egl-36 [S... [more]
shw-11.288e-6146.76SHaW family of potassium channels [Source:UniProt... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Shaw3.913e-8054.58gene:FBgn0003386 transcript:FBtr0332184[more]
Shaw4.908e-8054.58gene:FBgn0003386 transcript:FBtr0089274[more]
Shaw3.088e-7954.58gene:FBgn0003386 transcript:FBtr0332185[more]
Shaw3.669e-7954.58gene:FBgn0003386 transcript:FBtr0289989[more]
Shaw4.190e-7954.58gene:FBgn0003386 transcript:FBtr0089275[more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcna1b1.775e-4440.98potassium voltage-gated channel, shaker-related su... [more]
kcna1b1.775e-4440.98potassium voltage-gated channel, shaker-related su... [more]
kcna2b2.252e-4440.22potassium voltage-gated channel, shaker-related su... [more]
kcna1a2.632e-4441.06potassium voltage-gated channel, shaker-related su... [more]
kcna1a2.632e-4441.06potassium voltage-gated channel, shaker-related su... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNC23.181e-4840.51potassium channel, voltage gated Shaw related subf... [more]
KCNC28.245e-4840.51potassium channel, voltage gated Shaw related subf... [more]
KCNA18.095e-4741.73potassium channel, voltage gated shaker related su... [more]
fastkd32.649e-4643.65FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-... [more]
fastkd38.932e-4642.31FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnc23.229e-4739.78potassium voltage gated channel, Shaw-related subf... [more]
Kcnc24.045e-4739.78potassium voltage gated channel, Shaw-related subf... [more]
Kcna26.833e-4539.71potassium voltage-gated channel, shaker-related su... [more]
Kcna26.833e-4539.71potassium voltage-gated channel, shaker-related su... [more]
Kcna26.833e-4539.71potassium voltage-gated channel, shaker-related su... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17972|KCNAW_DROME4.920e-7954.58Potassium voltage-gated channel protein Shaw OS=Dr... [more]
sp|G5EFC3|KCNAG_CAEEL2.224e-7051.11Potassium voltage-gated channel protein egl-36 OS=... [more]
sp|P22462|KCNC2_RAT1.476e-4639.78Potassium voltage-gated channel subfamily C member... [more]
sp|Q96PR1|KCNC2_HUMAN1.939e-4641.67Potassium voltage-gated channel subfamily C member... [more]
sp|Q14B80|KCNC2_MOUSE2.830e-4639.78Potassium voltage-gated channel subfamily C member... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HGQ19.888e-8357.61Ion_trans domain-containing protein OS=Macrostomum... [more]
A0A1I8I9E91.429e-8157.97Ion_trans domain-containing protein OS=Macrostomum... [more]
A0A1I8HHR24.768e-8156.99Ion_trans domain-containing protein OS=Macrostomum... [more]
A0A267FE937.754e-8157.97BTB domain-containing protein OS=Macrostomum ligna... [more]
A0A1I8G8947.805e-8158.55Ion_trans domain-containing protein OS=Macrostomum... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcna1a7.187e-4642.21potassium voltage-gated channel subfamily A member... [more]
kcna2b8.691e-4539.64potassium voltage-gated channel subfamily A member... [more]
ENSAMXT00000014366.26.658e-4440.71potassium voltage-gated channel subfamily A member... [more]
kcnc26.117e-4340.23potassium voltage-gated channel, Shaw-related subf... [more]
kcnc26.941e-4340.23potassium voltage-gated channel, Shaw-related subf... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007589.12.599e-5443.43pep scaffold:Pmarinus_7.0:GL482983:7539:12291:-1 g... [more]
ENSPMAT00000001869.12.942e-4336.98pep scaffold:Pmarinus_7.0:GL480351:152:3521:-1 gen... [more]
kcnc1a3.030e-4341.76potassium voltage-gated channel, Shaw-related subf... [more]
ENSPMAT00000005395.13.373e-4332.31pep scaffold:Pmarinus_7.0:GL482646:8602:10978:-1 g... [more]
KCNA34.179e-4243.93potassium voltage-gated channel subfamily A member... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO398048.818e-4842.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO382378.924e-4335.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAK32.423e-4239.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAK66.423e-4241.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427241.099e-4042.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnc1b1.874e-4841.97potassium voltage-gated channel subfamily C member... [more]
kcnc1b2.558e-4841.97potassium voltage-gated channel subfamily C member... [more]
ENSORLT00000045623.12.541e-4740.86potassium voltage-gated channel subfamily C member... [more]
kcna1a2.256e-4541.98potassium voltage-gated channel subfamily A member... [more]
ENSORLT00000043885.19.244e-4542.08potassium voltage-gated channel subfamily A member... [more]
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BLAST of Potassium voltage-gated channel protein Shaw vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000013590.10.000e+099.72SMESG000013590.1[more]
SMESG000039493.12.078e-8656.83SMESG000039493.1[more]
SMESG000059794.19.033e-8656.63SMESG000059794.1[more]
SMESG000039493.11.743e-8556.83SMESG000039493.1[more]
SMESG000071446.15.480e-8456.93SMESG000071446.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032095 ID=SMED30032095|Name=Potassium voltage-gated channel protein Shaw|organism=Schmidtea mediterranea sexual|type=transcript|length=1163bp
AATTAATTGTTTTTATAAATGATTATGATTTAATTATTAATTTGAAATAT
CTCCTTTCAGATTCTTGGATATATCTCAGTGTTCTTTATTATTATTTCTC
TTATTGCTTTTTGTTTGAAATCTGTGCCAGTTTTAAAAGTTGCCAATATT
GTATCTGTAAATATAACGTCTTCGAATACTTGGGCTATCACGGCTAAAGA
TGGGGTCGGACCTGATCCCTACATCGCATTTTTATATGTCGAACTTATTT
GTAACTCTTACTTTACAATTGAATTAATTGTTCGTTTATTCGCTACGCCC
AGCATTTTTGCCTTTTTCAAATCGCCAATAAACCTAATTGATATATTCGC
TCTATTCAGCTTTTACTTGTATTTGGTTTTGTATTACTTAAACAGTCCTG
TCAGATTTAATATTTATTTAGAGACTTTCAATGTTGTCAGATTATTTCGC
ATATTTAAACTCACTCGACACATATCAGGCTTGAAGATTTTAATACTCAC
ATTCCAAGCGAGCATGAAAGAGCTTATTCTTCTGATGTTTTTTCTATTTG
TTTTTATTGTTGTTTTTGCGGCTTTTATATATTATGCTGAGCGATTGGAT
AGTAACATTGATACGCAGTTCATGTCTATTATTGACGGACTGTGGTGGTC
TCTAATTACAATGACTACTGTCGGATACGGAGATTATAGCCCTAGAAGCC
TTCCAGGAATGCTAGTTGGTGCACTTTGCGCTGTAACAGGTGTATTAACC
ATATCATTGCCAATTCCTGTTATTGTGAGTAACTTTTCAATGTTTTATTC
TCATACCCAAGCAAGAGCTAAGCTTCCAAAACAAAGACGAAGAGTGTTAC
CGGTCGAAGCAGTGAGACCAAAAGGTAAAGGACCACCGACTATGGGACCA
CCGAGAAAAAATAATCAGATCACTGATGTTGATTTTAGAAATAAAAAATC
TGAAATGGATGAAATAAGTAAGCCAAAAATTAATGGCTCCAATATACATA
AAGGACATAGACCAAGCATTCAGATGACTGGAAAGGTATTCCCAAAATCA
TTTCAAAAGTTAGAGGTTTCTCAAAACGACGACGAATCTCCAGTTACAAT
TGCAAGAAAGATCAACTCCATGGACACAAAATGACAAAATAAATTTGCAA
TTCCACTATGAAC
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protein sequence of SMED30032095-orf-1

>SMED30032095-orf-1 ID=SMED30032095-orf-1|Name=SMED30032095-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp
MKELILLMFFLFVFIVVFAAFIYYAERLDSNIDTQFMSIIDGLWWSLITM
TTVGYGDYSPRSLPGMLVGALCAVTGVLTISLPIPVIVSNFSMFYSHTQA
RAKLPKQRRRVLPVEAVRPKGKGPPTMGPPRKNNQITDVDFRNKKSEMDE
ISKPKINGSNIHKGHRPSIQMTGKVFPKSFQKLEVSQNDDESPVTIARKI
NSMDTK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR015572Shaw_inv
IPR003968K_chnl_volt-dep_Kv
IPR028325VG_K_chnl
IPR005821Ion_trans_dom
Vocabulary: cellular component
TermDefinition
GO:0008076voltage-gated potassium channel complex
GO:0016020membrane
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0031594neuromuscular junction
GO:0043679axon terminus
Vocabulary: molecular function
TermDefinition
GO:0005249voltage-gated potassium channel activity
GO:0005216ion channel activity
GO:0005244voltage-gated ion channel activity
GO:0005267potassium channel activity
Vocabulary: biological process
TermDefinition
GO:0006813potassium ion transport
GO:0006811ion transport
GO:0055085transmembrane transport
GO:0006810transport
GO:0007268chemical synaptic transmission
GO:0034765regulation of ion transmembrane transport
GO:0046928regulation of neurotransmitter secretion
GO:0051260protein homooligomerization
GO:0071805potassium ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003968Potassium channel, voltage dependent, KvPRINTSPR01491KVCHANNELcoord: 76..87
score: 73.68
coord: 3..17
score: 46.94
NoneNo IPR availablePRINTSPR00169KCHANNELcoord: 36..58
score: 60.96
coord: 65..91
score: 63.76
coord: 3..26
score: 47.9
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 1..95
e-value: 2.2E-29
score: 104.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 184..206
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 3..110
NoneNo IPR availableTMHMMTMhelixcoord: 66..88
NoneNo IPR availableTMHMMTMhelixcoord: 4..26
NoneNo IPR availableTMHMMTMhelixcoord: 39..56
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 1..98
e-value: 7.4E-16
score: 58.1
IPR028325Voltage-gated potassium channelPANTHERPTHR11537VOLTAGE-GATED POTASSIUM CHANNELcoord: 2..127
IPR015572Potassium channel, voltage dependent, Shaw, invertebratePANTHERPTHR11537:SF257POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAWcoord: 2..127