RIIa domain-containing protein 1

Overview
NameRIIa domain-containing protein 1
Smed IDSMED30032094
Length (bp)772
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RIIa domain-containing protein 1 (SMED30032094) t-SNE clustered cells

Violin plots show distribution of expression levels for RIIa domain-containing protein 1 (SMED30032094) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RIIa domain-containing protein 1 (SMED30032094) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RIIa domain-containing protein 1 (SMED30032094) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30032094

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30032094SMESG000079320.1 SmedASXL_012116SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
Smed sexual biotypeSMED30032094SMESG000079320.1 Contig31127newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032094SMESG000079320.1 Contig31127uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032094SMESG000079320.1 Contig970newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032094SMESG000079320.1 Contig970uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032094SMESG000017644.1 Contig970newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30032094SMESG000017644.1 Contig970uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30032094SMESG000079320.1 dd_Smed_v6_4716_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30032094SMESG000079320.1 dd_Smed_v4_4716_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Human
Match: RIIAD1 (regulatory subunit of type II PKA R-subunit domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26686])

HSP 1 Score: 72.7886 bits (177), Expect = 4.736e-16
Identity = 39/84 (46.43%), Postives = 56/84 (66.67%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
            D GALS  Q  +L + KI  R+ NE YLR H E+E +IS F R    ++F+K+P++I E+AA+YFTD  LP +I  Q+  +K+A
Sbjct:   12 DPGALSAAQLEQLRKFKIQTRIANEKYLRTHKEVEWLISGFFR----EIFLKRPDNILEFAADYFTDPRLPNKIHMQLIKDKKA 91
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Human
Match: RIIAD1 (regulatory subunit of type II PKA R-subunit domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26686])

HSP 1 Score: 62.003 bits (149), Expect = 7.248e-12
Identity = 32/70 (45.71%), Postives = 48/70 (68.57%), Query Frame = 2 
Query:  206 QLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
            + KI  R+ NE YLR H E+E +IS F R    ++F+K+P++I E+AA+YFTD  LP +I  Q+  +K+A
Sbjct:   36 KWKIQTRIANEKYLRTHKEVEWLISGFFR----EIFLKRPDNILEFAADYFTDPRLPNKIHMQLIKDKKA 101
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Zebrafish
Match: si:dkey-71b5.6 (si:dkey-71b5.6 [Source:NCBI gene;Acc:100294632])

HSP 1 Score: 85.5001 bits (210), Expect = 3.946e-21
Identity = 44/82 (53.66%), Postives = 59/82 (71.95%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEK 406
            D GALS EQQ KL Q KI  R+ NE YLR+HPE+E ++S FLR    D+F+K+P D+RE+AA++F D  LP +I+ Q+ I K
Sbjct:   12 DFGALSLEQQEKLRQFKIKTRIANEKYLRSHPEVEMLLSDFLR----DLFLKRPADVREFAADHFRDPGLPTKIQAQMNINK 89
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Mouse
Match: Riiad1 (regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 [Source:MGI Symbol;Acc:MGI:1913603])

HSP 1 Score: 70.8626 bits (172), Expect = 3.174e-15
Identity = 41/95 (43.16%), Postives = 55/95 (57.89%), Query Frame = 2 
Query:  131 MEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
            ME      V  D G L+ EQ  +L   KI  R+ NE YLR H E+  +IS F R    ++F+K+P++I E+AA YFTD  LP RI  Q+  EK+ 
Sbjct:   28 METRGHGIVGPDPGTLNPEQLEQLRDFKIQTRIANEKYLRTHKEVSLLISGFFR----EMFLKRPDNILEFAAHYFTDPRLPSRIHMQLIKEKKG 118
[Close]
BLAST of RIIa domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|A6NNX1|RIAD1_HUMAN (RIIa domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RIIAD1 PE=4 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 2.275e-15
Identity = 39/84 (46.43%), Postives = 56/84 (66.67%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
            D GALS  Q  +L + KI  R+ NE YLR H E+E +IS F R    ++F+K+P++I E+AA+YFTD  LP +I  Q+  +K+A
Sbjct:   12 DPGALSAAQLEQLRKFKIQTRIANEKYLRTHKEVEWLISGFFR----EIFLKRPDNILEFAADYFTDPRLPNKIHMQLIKDKKA 91
[Close]
BLAST of RIIa domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q3KNY5|RIAD1_MOUSE (RIIa domain-containing protein 1 OS=Mus musculus OX=10090 GN=Riiad1 PE=2 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 2.220e-14
Identity = 41/95 (43.16%), Postives = 55/95 (57.89%), Query Frame = 2 
Query:  131 MEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
            ME      V  D G L+ EQ  +L   KI  R+ NE YLR H E+  +IS F R    ++F+K+P++I E+AA YFTD  LP RI  Q+  EK+ 
Sbjct:   28 METRGHGIVGPDPGTLNPEQLEQLRDFKIQTRIANEKYLRTHKEVSLLISGFFR----EMFLKRPDNILEFAAHYFTDPRLPSRIHMQLIKEKKG 118
[Close]
BLAST of RIIa domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q32PB2|RIAD1_BOVIN (RIIa domain-containing protein 1 OS=Bos taurus OX=9913 GN=RIIAD1 PE=4 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.988e-14
Identity = 39/81 (48.15%), Postives = 53/81 (65.43%), Query Frame = 2 
Query:  173 ALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKEA 412
             LS EQ  KL   KI  R+ NE YLR H E+E +IS F R    ++F+K+P++I E+AA+YFTD  LP +I  Q+  EK+A
Sbjct:   15 TLSPEQLEKLRGFKIQTRITNEKYLRTHKEVELLISGFFR----EMFLKRPDNIPEFAADYFTDPRLPNKIHMQLIKEKKA 91
[Close]
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Match: A0A1S3HYU9 (RIIa domain-containing protein 1 OS=Lingula unguis OX=7574 GN=LOC106158723 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 1.323e-30
Identity = 56/95 (58.95%), Postives = 70/95 (73.68%), Query Frame = 2 
Query:  101 DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRI 385
            D PKH PP GMEPYD+     DLGALS EQQ KLN+ KI  RLENE YLRNHPE+EC+++ FL     D+  K+PN++RE+A+ YFTD DLP ++
Sbjct:    3 DKPKHKPPEGMEPYDLGGQ-GDLGALSPEQQEKLNRFKIQTRLENEKYLRNHPEVECLLTGFL----GDILRKRPNNVREFASSYFTDPDLPDKV 92
[Close]
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Match: A0A1I8I933 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028497g1 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 7.043e-30
Identity = 56/94 (59.57%), Postives = 72/94 (76.60%), Query Frame = 2 
Query:  107 PKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE 388
            P+HDPP  MEPYD+    DDLGALS +QQ +LN++KI  RL NE YLR HPEI+C+IS FL    ++ FI++P ++RE+AAEYFTDS LP R+E
Sbjct:   10 PRHDPPHSMEPYDLGG-GDDLGALSEDQQRQLNEVKIKKRLANEAYLRAHPEIDCLISGFL----QEAFIRKPANVREFAAEYFTDSALPDRVE 98
[Close]
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Match: A0A2C9KXS7 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106073494 PE=4 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 1.523e-28
Identity = 55/97 (56.70%), Postives = 69/97 (71.13%), Query Frame = 2 
Query:  101 DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIEQ 391
            D PKH PP GME +D+  V +DLGALS  QQA LNQ KI  R+ NE YLR HPE+EC+I+ FL     DV +K+P  IRE+AAEYFT+  LP ++E+
Sbjct:    3 DQPKHGPPHGMEKHDLGGV-NDLGALSQAQQADLNQFKIKTRIGNEKYLREHPEVECLIAGFL----SDVLMKRPESIREFAAEYFTNPTLPDKVEK 94
[Close]
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Match: A0A0B7AIP6 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF123134 PE=4 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 8.968e-28
Identity = 58/104 (55.77%), Postives = 70/104 (67.31%), Query Frame = 2 
Query:  101 DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIE-QIAIEKE 409
            D PKH PP GME YD+    DDLGALS  QQA LN  KI  R+ NE YLR+HPE+EC+I+ FL     DV  K+P  IRE+AAEYFT+  LP  +E Q+A  +E
Sbjct:    6 DKPKHGPPHGMEKYDLGG-DDDLGALSVAQQADLNHFKIKTRIGNESYLRDHPEVECLIAGFL----GDVLTKRPESIREFAAEYFTNPSLPEILEKQLAGRQE 104
[Close]
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Match: A0A3S0Z919 (Uncharacterized protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_020089 PE=4 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.309e-27
Identity = 53/95 (55.79%), Postives = 68/95 (71.58%), Query Frame = 2 
Query:  107 PKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIEQ 391
            PKH+PP GME YD+    DDLGALS  QQA LNQ KI  R+ NE YLR+HPE+EC+++ FL     DV  K+P+ +RE+AAEYFT+  LP  +E+
Sbjct:   42 PKHEPPHGMEKYDLGG-KDDLGALSLAQQADLNQFKIKTRMGNEKYLRDHPEVECLVAGFL----GDVLTKRPDSVREFAAEYFTNPSLPETLEK 131
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000052836.1 (regulatory subunit of type II PKA R-subunit domain containing 1 [Source:NCBI gene;Acc:103039641])

HSP 1 Score: 85.1149 bits (209), Expect = 4.257e-21
Identity = 42/74 (56.76%), Postives = 54/74 (72.97%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRI 385
            D GALS EQQ KL Q KI  R+ NE YLR HPE++ ++S FLR    DVF+K+P DIR++AA+YF D +LP +I
Sbjct:    6 DPGALSPEQQEKLRQFKIKTRIANEMYLRAHPEVDVLLSDFLR----DVFLKRPADIRKFAADYFIDPNLPEKI 75
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO45600 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSB0])

HSP 1 Score: 86.6557 bits (213), Expect = 6.500e-22
Identity = 38/79 (48.10%), Postives = 55/79 (69.62%), Query Frame = 2 
Query:  149 SSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRI 385
             S  +D GAL+ EQQ KLNQ KI+ R+ENE YLR+HPE+ C+++ FL      +  ++P ++RE+AA YF+D  LP R+
Sbjct:   12 GSEGNDAGALTAEQQTKLNQFKIDTRIENERYLRDHPEVSCLLTGFL----GSILQERPENVREFAAGYFSDKTLPDRV 86
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Medaka
Match: ENSORLT00000033757.1 (regulatory subunit of type II PKA R-subunit domain containing 1 [Source:NCBI gene;Acc:101173333])

HSP 1 Score: 70.4774 bits (171), Expect = 1.690e-15
Identity = 32/66 (48.48%), Postives = 45/66 (68.18%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFT 361
            D   L+ EQQ KL Q KI  R++NE Y+R HPE+E +I  FLR    ++ +K+P DIRE+A +YF+
Sbjct:   11 DTSVLNAEQQEKLRQFKIKTRIDNEKYIRAHPEVEVLIGDFLR----EILLKRPADIREFAGDYFS 72
[Close]
BLAST of RIIa domain-containing protein 1 vs. Ensembl Medaka
Match: ENSORLT00000035224.1 (regulatory subunit of type II PKA R-subunit domain containing 1 [Source:NCBI gene;Acc:101173333])

HSP 1 Score: 63.929 bits (154), Expect = 8.577e-13
Identity = 30/62 (48.39%), Postives = 41/62 (66.13%), Query Frame = 2 
Query:  164 DLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAA 349
            D   L+ EQQ KL Q KI  R++NE Y+R HPE+E +I  FLR    ++ +K+P DIRE+A 
Sbjct:   11 DTSVLNAEQQEKLRQFKIKTRIDNEKYIRAHPEVEVLIGDFLR----EILLKRPADIREFAG 68
[Close]
BLAST of RIIa domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000079320.1 (SMESG000079320.1)

HSP 1 Score: 201.83 bits (512), Expect = 2.658e-66
Identity = 100/104 (96.15%), Postives = 100/104 (96.15%), Query Frame = 2 
Query:  101 DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIEQIAIEKEA 412
            DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLR    DVFIKQPNDIREYAAEYFTDSDLPLRIEQIAIEKEA
Sbjct:    4 DPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEFYLRNHPEIECMISAFLR----DVFIKQPNDIREYAAEYFTDSDLPLRIEQIAIEKEA 103
The following BLAST results are available for this feature:
BLAST of RIIa domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
RIIAD14.736e-1646.43regulatory subunit of type II PKA R-subunit domain... [more]
RIIAD17.248e-1245.71regulatory subunit of type II PKA R-subunit domain... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:dkey-71b5.63.946e-2153.66si:dkey-71b5.6 [Source:NCBI gene;Acc:100294632][more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Riiad13.174e-1543.16regulatory subunit of type II PKA R-subunit (RIIa)... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|A6NNX1|RIAD1_HUMAN2.275e-1546.43RIIa domain-containing protein 1 OS=Homo sapiens O... [more]
sp|Q3KNY5|RIAD1_MOUSE2.220e-1443.16RIIa domain-containing protein 1 OS=Mus musculus O... [more]
sp|Q32PB2|RIAD1_BOVIN2.988e-1448.15RIIa domain-containing protein 1 OS=Bos taurus OX=... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HYU91.323e-3058.95RIIa domain-containing protein 1 OS=Lingula unguis... [more]
A0A1I8I9337.043e-3059.57Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A2C9KXS71.523e-2856.70Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A0B7AIP68.968e-2855.77Uncharacterized protein (Fragment) OS=Arion vulgar... [more]
A0A3S0Z9191.309e-2755.79Uncharacterized protein (Fragment) OS=Elysia chlor... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSAMXT00000052836.14.257e-2156.76regulatory subunit of type II PKA R-subunit domain... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO456006.500e-2248.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSORLT00000033757.11.690e-1548.48regulatory subunit of type II PKA R-subunit domain... [more]
ENSORLT00000035224.18.577e-1348.39regulatory subunit of type II PKA R-subunit domain... [more]
back to top
BLAST of RIIa domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000079320.12.658e-6696.15SMESG000079320.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032094 ID=SMED30032094|Name=RIIa domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=772bp
GTGAGGGGTTTAATATTTGTAAATATTCTAGATTATAAATATTTTTTTAA
ATAAATTTTACTTTTAATTTTCATTCATCCAAATAATATAAATGAGTTCC
GATCCACCAAAACACGATCCTCCTAGAGGCATGGAACCGTATGATATTTC
ATCCGTTCCCGATGATCTTGGAGCTTTAAGTACTGAACAACAAGCAAAAT
TGAATCAATTAAAAATTAACATGAGACTAGAAAATGAATTTTATCTCAGA
AATCACCCGGAGATTGAATGTATGATATCAGCATTTCTCAGGAAATTGAA
CAAAGATGTATTTATCAAACAACCGAATGATATTCGAGAATACGCCGCAG
AATATTTTACAGATTCTGATTTGCCGCTGAGAATCGAGCAAATCGCAATA
GAGAAGGAAGCCAATCAGAATCGAAATAATGTTATTCAGAATATTAATAA
TATCGACAGAAATTAATTTCAATTGTTGTTTTCTGAATTCTATTTAATTA
TAAGATTATTTTTATTATTTTGCAGTTTAAGTTGATAAATTTAATAGTAG
TAAATCTTATTTCTAGAATGTGTTACTGGTGATTGGCTGAAATTTGATGA
TGTTTATTTGTTACTCATTTTAGCATCAGATGGCTTTCGGAGGAAATTCT
CAAGGTTTGTAAGGCTACATTTATTGTTGCAGAGTTTTCAGTTTTGTTTC
TTTGAGTTTTATATTTGTTTAAATCTAAACAAAAGGATTAGAGAAATCAA
TTTTACATATTTACAAATTTAC
back to top

protein sequence of SMED30032094-orf-1

>SMED30032094-orf-1 ID=SMED30032094-orf-1|Name=SMED30032094-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=125bp
MSSDPPKHDPPRGMEPYDISSVPDDLGALSTEQQAKLNQLKINMRLENEF
YLRNHPEIECMISAFLRKLNKDVFIKQPNDIREYAAEYFTDSDLPLRIEQ
IAIEKEANQNRNNVIQNINNIDRN*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR003117cAMP_dep_PK_reg_su_I/II_a/b
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process