Spondin-1

Overview


Name	Spondin-1
Smed ID	SMED30032088
Length (bp)	1776

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Expression Details

Spondin-1 ( spondin1-like ) is expressed during Stage 2, Stage 3 and Stage 4 in the blastomere, primitive ectoderm and primitive ectoderm cell

Click to see image symbols and abbreviations


Abbreviation or symbol	Definition
O	oral hemisphere
A	aboral hemisphere
D	dorsal
V	ventral
L	lateral
black arrowhead	embryonic pharynx
red arrowhead	definitive pharynx
black arrows	primitive gut
yellow arrows	primitive ectoderm cells
cyan arrows	brain
cyan arrowheads	nerve cords
blue arrowheads	eye progenitors (trail cells)
purple arrowheads	eyes
scale bar	100 µm

Anatomical Expression

PAGE et. al., 2020

SMED30032088

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
primitive ectoderm	SMED30032088	SMED30032088	smed_20140614	PMID:28072387 Davies et al., 2017
primitive ectoderm	SMED30032088	SMED30032088	smed_20140614	PMID:28072387 Davies et al., 2017
primitive ectoderm	SMED30032088	SMED30032088	smed_20140614	PMID:28072387 Davies et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Spondin-1 vs. Ensembl Human
Match: SPON1 (spondin 1 [Source:HGNC Symbol;Acc:HGNC:11252])

HSP 1 Score: 85.1149 bits (209), Expect = 1.571e-16
Identity = 66/249 (26.51%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTLGRNGA---------------------------------VEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P      V  +   +  + ++    +  N +                                  + +     P  +    + C  SEW +WSPCS+ CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKC 548

HSP 2 Score: 53.9138 bits (128), Expect = 7.039e-7
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC+++EWS W  C+KSCG G   + R+IQ +   GG PCP   + +KC  + C
Sbjct:  667 IDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKC 720

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BLAST of Spondin-1 vs. Ensembl Human
Match: SPON2 (spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253])

HSP 1 Score: 77.411 bits (189), Expect = 7.885e-15
Identity = 61/199 (30.65%), Postives = 85/199 (42.71%), Query Frame = 1

Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDT-----------PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNL 636
            + S  + V R H+L S +  + PSPDW  GV  +DLC DG +W+    + LYP DAG  +G T+   N   + + DT+ EI      S+P  P             P+A +TL R+           PV            SR N +  + +V +   LD           C  S W+SW  C   CG  G  SRTR +
Sbjct:  135 QTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLC-DGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQ-DTVTEIT----SSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPV----------LPSRDNEIVDSASVPE-TPLD-----------CEVSLWSSWGLCGGHCGRLGTKSRTRYV 305

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Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDT-----------PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNL 636
            + S  + V R H+L S +  + PSPDW  GV  +DLC DG +W+    + LYP DAG  +G T+   N   + + DT+ EI      S+P  P             P+A +TL R+           PV            SR N +  + +V +   LD           C  S W+SW  C   CG  G  SRTR +
Sbjct:  135 QTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLC-DGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQ-DTVTEIT----SSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPV----------LPSRDNEIVDSASVPE-TPLD-----------CEVSLWSSWGLCGGHCGRLGTKSRTRYV 305

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Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDT-----------PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNL 636
            + S  + V R H+L S +  + PSPDW  GV  +DLC DG +W+    + LYP DAG  +G T+   N   + + DT+ EI      S+P  P             P+A +TL R+           PV            SR N +  + +V +   LD           C  S W+SW  C   CG  G  SRTR +
Sbjct:  135 QTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLC-DGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQ-DTVTEIT----SSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPV----------LPSRDNEIVDSASVPE-TPLD-----------CEVSLWSSWGLCGGHCGRLGTKSRTRYV 305

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BLAST of Spondin-1 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 53.5286 bits (127), Expect = 4.619e-7
Identity = 37/140 (26.43%), Postives = 67/140 (47.86%), Query Frame = 1

Query:  979 TRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTI-------WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCR 1377
            TR+FY+ +T +CE FKY  C  GN+NNF T++ C+N+C    ++ P   + +    Q     +   SL+ ++  +P     E      C+    + +       +YY+    KC+      C G  N F++  +C++ C+
Sbjct:  139 TRYFYNNQTKQCERFKYGGC-LGNMNNFETLEECKNIC----EDGPNGFQVDNYGTQLN---AVNNSLTPQSTKVPS--LFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268

HSP 2 Score: 51.2174 bits (121), Expect = 2.749e-6
Identity = 36/131 (27.48%), Postives = 64/131 (48.85%), Query Frame = 1

Query:  982 RFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            RFF++I T +CE F Y  C+ GN N F +++ C+ +C++      +I ++ L                Q+ K  P+FCF E D     +     T ++Y+++ ++C+      C G +N F T ++C   C
Sbjct:   69 RFFFNIFTRQCEEFIYGGCE-GNQNRFESLEECKKMCTR--DNANRIIKTTL----------------QQEK--PDFCFLEEDPG---ICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175

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BLAST of Spondin-1 vs. Ensembl Celegans
Match: spon-1 (SPONdin (Extracellular matrix glycoprotein) family [Source:UniProtKB/TrEMBL;Acc:Q19305])

HSP 1 Score: 108.227 bits (269), Expect = 2.486e-24
Identity = 115/399 (28.82%), Postives = 169/399 (42.36%), Query Frame = 1

Query:   79 RSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETY-KPNNVTRLDEPDTIREINKIWMKSNPFTP------DT-PVAEITLTRVEPQKDTQC-----VKTPVKGV-NEFQNAQKESR--------------SNTLGRNGAVEKYNVLDDPQLAQM----------------------AKAF---CGFSEWTSWSPCSVKCGEGETSRTRNLI--KNLKNELCIQLPRKEQKNCAGARL-ECDLXXXXXXXXXXXXXXX--XASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLD--KTDFRCDPISICSAGKLA-PCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVC 1092
            +S FV VN+ H+  S+ +M GPSPDWC G+S ++LC+  C W    T  L P DAG  +G TY  PN  T   EP     I+ I  K NP +P      DT P     + R +    ++C     +K     + N  ++ + + R              S T G+ G   +  V   P  AQ+                      ++AF   C  S W SW  CSV+CG G  SR R  +       +  + L RK+   C G    +C+++        +       SASC  EG  +R R F  S+ +  CM      + LQ+  TC +   +     +   IC   K A  C    P  R++Y+ +  +CE F +  C KGN N F T + C+ +C
Sbjct:  292 KSQFV-VNKYHHFVSLATMFGPSPDWCVGLSSVNLCLPDCTWAEERTFELQPFDAGTDSGPTYMSPNEPTEPREP-----IHWITTKLNPLSPFYNSKSDTIPTLAKVILRRKNVTSSECKSDDILKAEAHNITNTSEDEEYKDRRECMMTQWEPWSLCSATCGK-GIRIRSRVYVFPIKAQVFHCHRQTTEKQFCNAKINECENSEAFSSKCQVSSWGSWGECSVQCGHGMRSRNRTFLNPATKSGDCSVDLERKDI--CVGENGDDCNVTPDPLCKTTAWSDWSPCSASC-DEGVRVRTRLFFYSEHEKRCM-----HVNLQEKDTCVMQSCRRFIEINSEEICQEDKQAGQCAGNFP--RYWYNHEKTQCERFIFTGC-KGNRNQFETEEECKQIC 672

HSP 2 Score: 65.855 bits (159), Expect = 6.222e-11
Identity = 50/190 (26.32%), Postives = 84/190 (44.21%), Query Frame = 1

Query: 1090 CSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFC--FHEVDSSKTCMKSKPKTI-------WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQ-----------LESLK-------LDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCP-VLYESRKCFSKPC 1575
            CS    E  ++R + L             +L +K   + + C  F E++S + C + K           ++Y+H   +C+  +   CKG  N+F T ++C + C P  +           LE           ++VDC+VS+W+ W  CS SCG G + + R + K + NGG  C   L +  +C  +PC
Sbjct:  570 CSASCDEGVRVR-TRLFFYSEHEKRCMHVNLQEKDTCVMQSCRRFIEINSEEICQEDKQAGQCAGNFPRYWYNHEKTQCERFIFTGCKGNRNQFETEEECKQICLPGYEKSKSLIPNNQLLEDFGNTEVDDGGERVDCEVSKWTAWGSCSVSCGRGKKSRSRHVVKLARNGGHQCSEHLMQELQCRLRPC 758

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BLAST of Spondin-1 vs. Ensembl Celegans
Match: E01G6.1 (pep chromosome:WBcel235:X:12260881:12266537:1 gene:WBGene00008449.1 transcript:E01G6.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:E01G6.1)

HSP 1 Score: 66.6254 bits (161), Expect = 4.243e-11
Identity = 48/157 (30.57%), Postives = 69/157 (43.95%), Query Frame = 1

Query:  937 SAGKLAPCIN-GKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVC----SKVIQELPKIRRSNLALLQAR------TSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            SAG   PC   G    RF+++  T KC+PF YY C  GN NNF T+D C+N C          L  ++  N  L +          Y   +S S    +    C   +     C  S  +++W+Y    +KC   V   C GT N+F+T   C ++C
Sbjct:  443 SAG--TPCFGRGLTIQRFYFNPSTQKCQPFHYYGCS-GNGNNFETVDQCQNFCLHSADSACDGLVPLKNPNSELQRCSEEDPCPAGYECNDS-SYCCPSSENACNANMSRGNGCKGSTQRSMWFYDKSKKKCSQFVYNGCGGTPNRFTTKVACTESC 595

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BLAST of Spondin-1 vs. Ensembl Celegans
Match: K10D3.4 (pep chromosome:WBcel235:I:7134738:7139973:-1 gene:WBGene00010738.1 transcript:K10D3.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K10D3.4)

HSP 1 Score: 58.9214 bits (141), Expect = 8.067e-9
Identity = 43/155 (27.74%), Postives = 61/155 (39.35%), Query Frame = 1

Query:  967 GKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTC----------MKSKPK-----TIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDS 1386
            G    R++++ KTG CE F Y  C+ GN NNF T   C++ C     E   I+ + L             S +        +C+++  +   C           KS        T WYY    R CQ+     C G  N F+T  DC   CR +S
Sbjct:  421 GTYSNRWWFNAKTGNCEEFIYSGCQ-GNANNFETYKECQDYCRDARSEPQCIQGTALTDSNGNFIICGGSSAASTTCPANHYCYYDGTTYGCCPTQAYTCSLSYKSGASCGPAVTRWYYDSTTRTCQTYSFNGCDGNSNNFATQQDCKDYCRVES 574

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BLAST of Spondin-1 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 52.7582 bits (125), Expect = 7.845e-7
Identity = 42/143 (29.37%), Postives = 62/143 (43.36%), Query Frame = 1

Query:  958 CINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVC--SKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRP 1380
            C N  P  R+F++ +TG+CE F Y  C  GN NNF   ++CE  C    VI          LA +  R S+  ++S S K  N+                      WY++ +N +C+  V     G  N+F T  +C + C P
Sbjct: 2057 CTNYTP--RWFFNSQTGQCEQFAYGSCG-GNENNFFDRNTCERKCMPHHVI----------LAQVPDRCSFD-KDSGSGKGYNV---------------------KWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTP 2164

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BLAST of Spondin-1 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 52.7582 bits (125), Expect = 8.210e-7
Identity = 42/143 (29.37%), Postives = 62/143 (43.36%), Query Frame = 1

Query:  958 CINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVC--SKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRP 1380
            C N  P  R+F++ +TG+CE F Y  C  GN NNF   ++CE  C    VI          LA +  R S+  ++S S K  N+                      WY++ +N +C+  V     G  N+F T  +C + C P
Sbjct: 2186 CTNYTP--RWFFNSQTGQCEQFAYGSCG-GNENNFFDRNTCERKCMPHHVI----------LAQVPDRCSFD-KDSGSGKGYNV---------------------KWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTP 2293

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BLAST of Spondin-1 vs. Ensembl Fly
Match: fat-spondin (gene:FBgn0026721 transcript:FBtr0086975)

HSP 1 Score: 93.9745 bits (232), Expect = 1.004e-19
Identity = 73/228 (32.02%), Postives = 111/228 (48.68%), Query Frame = 1

Query:   67 LNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETY-KPNNVTRLDEPDTIREINKIWMKS------NPFTPD-TPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNL---KNELCIQLPRKEQKNCAGARLEC 717
            +N+  S    V+R H   S++SM GPSPDW  G+SG+DLC + C WK ++   L+P DAG  +G +Y  PN+ T+   P+ +  I  ++ +       NP + + TP+A++ L R E      C        +EF  A +                 V DD +  Q  +A C   ++++WSPCSV CG+G   R+R  +      +N+   QL  KE   C  A  EC
Sbjct:  281 VNQNTSSKFRVDRKHPKVSLVSMFGPSPDWVVGISGLDLCTEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQ--PPERMYRITTMYPEDPRAPFYNPKSREMTPLAKLYLRR-EKIVSRNCD-------DEFLQALQ---------------LEVSDDAE-EQDTRAECRVGDYSAWSPCSVSCGKGIRMRSRQYLYPAAADQNKCARQLVAKEM--CVAAIPEC 480

HSP 2 Score: 69.3218 bits (168), Expect = 5.243e-12
Identity = 38/104 (36.54%), Postives = 54/104 (51.92%), Query Frame = 1

Query: 1270 WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV-DCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCP-VLYESRKCFSKPC 1575
            + Y  +N+ C S     C+G  N F T +DC+ TC       S ++D+   C +S+WS+W PCS SCG G    +R +  +  NGG PC   L +SR C    C
Sbjct:  660 YAYDPQNQHCYSFTYGGCRGNRNNFLTENDCLNTCNVLRSPYSSRVDQPRACVLSDWSVWSPCSVSCGVGVSESRRYVVTEPQNGGQPCSKRLVKSRSCAMPAC 763

HSP 3 Score: 51.9878 bits (123), Expect = 1.297e-6
Identity = 62/225 (27.56%), Postives = 89/225 (39.56%), Query Frame = 1

Query:  454 AQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLEC-----DLXXXXXXXXXXXXXXXXASCTTEGKMIRIR--KFARSKEKDECMKNVKPEIILQQVKTCKLDKTDFRCD---PISIC-SAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCS 1095
            AQ + R +  G N A  +  V  + + A      C  S W+ WS CS  CG G T RTR  + +L  + C  +   E+  C   R +C     +L          S     +S    G  IR R        +K+ C + ++    L Q K C ++  D   +      IC  A    PC       R+ Y  +   C  F Y  C +GN NNF T + C N C+
Sbjct:  485 AQSKDRDDDEGENLANSQSLVGSNGEGA----GLCKTSPWSVWSECSASCGIGITMRTRTFVNHLGRKRCPHITIVEKNKC--MRPDCTYEQVELPDPQCPTSQWSDWSPCSSTCGRGVTIRTRLLLLENGPDKESCTQRME----LHQQKEC-VNPIDCHINAEQAKDICVQAPDPGPCRGT--YMRYAYDPQNQHCYSFTYGGC-RGNRNNFLTENDCLNTCN 695

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BLAST of Spondin-1 vs. Ensembl Fly
Match: CG30046 (gene:FBgn0050046 transcript:FBtr0087895)

HSP 1 Score: 93.5893 bits (231), Expect = 1.543e-19
Identity = 75/266 (28.20%), Postives = 112/266 (42.11%), Query Frame = 1

Query:   91 VSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKS--NPF-----TPDTPVAEITLTRV--------------EPQKDTQCVKTP-----------------------------VKGVNEFQNAQKESRSNTLGRNGAV---EKYNVLD-DP-----QLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPR---KEQKNCAG 702
            V V+  H++ S  S + PSPDW  GV+G++LC+  C W     I LYP D G  +G TY  ++  ++  PD IR +   +     +PF     TP  P+A +T+ R               +P    +C   P                             V   NE Q  ++E +    G+N  +   E++  L+ DP     Q +Q  +A C  S W SWSPCSV CG+G   R R  +       C  + R   +E + C+G
Sbjct:  294 VRVDPIHHMVSFASKIEPSPDWIVGVTGLELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQV-PPDVIRRMRSDFPNDPRSPFYDISGTPMKPMAILTVKRQRIYERRCADEDSNNDPDVPRECFTHPWSSWSDCSSKCGVGMQYRRRVYKQPELARVYNCNEAQYEERECQGEMCGQNNLMREPEEFEDLEPDPRRIGYQPSQQRRAECELSSWGSWSPCSVTCGDGYEMRQRQYLNPQAEFDCQGVHRMELQETRKCSG 558

[Close]

BLAST of Spondin-1 vs. Ensembl Fly
Match: CG30046 (gene:FBgn0050046 transcript:FBtr0339627)

HSP 1 Score: 93.5893 bits (231), Expect = 1.543e-19
Identity = 75/266 (28.20%), Postives = 112/266 (42.11%), Query Frame = 1

Query:   91 VSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKS--NPF-----TPDTPVAEITLTRV--------------EPQKDTQCVKTP-----------------------------VKGVNEFQNAQKESRSNTLGRNGAV---EKYNVLD-DP-----QLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPR---KEQKNCAG 702
            V V+  H++ S  S + PSPDW  GV+G++LC+  C W     I LYP D G  +G TY  ++  ++  PD IR +   +     +PF     TP  P+A +T+ R               +P    +C   P                             V   NE Q  ++E +    G+N  +   E++  L+ DP     Q +Q  +A C  S W SWSPCSV CG+G   R R  +       C  + R   +E + C+G
Sbjct:  294 VRVDPIHHMVSFASKIEPSPDWIVGVTGLELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQV-PPDVIRRMRSDFPNDPRSPFYDISGTPMKPMAILTVKRQRIYERRCADEDSNNDPDVPRECFTHPWSSWSDCSSKCGVGMQYRRRVYKQPELARVYNCNEAQYEERECQGEMCGQNNLMREPEEFEDLEPDPRRIGYQPSQQRRAECELSSWGSWSPCSVTCGDGYEMRQRQYLNPQAEFDCQGVHRMELQETRKCSG 558

[Close]

BLAST of Spondin-1 vs. Ensembl Fly
Match: CG17739 (gene:FBgn0033710 transcript:FBtr0087893)

HSP 1 Score: 91.2781 bits (225), Expect = 9.681e-19
Identity = 67/235 (28.51%), Postives = 103/235 (43.83%), Query Frame = 1

Query:   97 VNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSN-PFTPDTPVAEITLTRVEP-------------------------------------QKDTQCVKTPVKGVNEFQNAQKESRS----------NTLGRN--GAVEKYNVLDDPQLAQMAKAF----CGFSEWTSWSPCSVKCGEGETSRTRNLI 639
            V+  H+L S++SM+ PSPDW  GVSG++LC+  C W  N    LYP DAG  +G +Y   +  ++  PD +R I     KSN P  P +P  + T  +++P                                     +  T+C       + EF+N    SR           N +G    G  E+     +P++A    +     CG S+W+ WS C+V CG GE +R+R+ +
Sbjct:  286 VDSNHHLISLVSMVDPSPDWIVGVSGLELCLPNCSWVENKVHNLYPWDAGTDSGPSYMSADQPQV-PPDVVRRI-----KSNFPNDPRSPFYDPTGAQMKPLATLHINRRRLYEKNCESSDSEQVPPECATNSWSRWDECTTKCGPGKQYRIREFKNPALASRHRCNNALREEKNCVGHKCAGFNEETAEGGEPEVAPSPGSSDDPQCGLSDWSEWSSCTVTCGTGEMTRSRHYL 514

HSP 2 Score: 67.0106 bits (162), Expect = 3.229e-11
Identity = 40/127 (31.50%), Postives = 62/127 (48.82%), Query Frame = 1

Query: 1201 IPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLD---KVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCP-VLYESRKCFSK 1569
            +P FC+ E+  S  C  +     WYY H + +C       C    NKF + ++C +TCR     + L+ D    +DC VS+W +   C+ SCG G Q + R + +    GG PCP  L    +C+ +
Sbjct:  658 VPGFCYDELTDSP-CRDNDVANFWYYDHVSDQCAIYWSDRCDTNRNKFKSKEECEETCRLPRHKQELQHDGIPAIDCLVSDW-VSHSCNASCGDGFQLRTRRVLRTPKYGGKPCPKHLVRLDRCYQR 782

[Close]

BLAST of Spondin-1 vs. Ensembl Fly
Match: CG30203 (gene:FBgn0050203 transcript:FBtr0273303)

HSP 1 Score: 81.6481 bits (200), Expect = 9.548e-16
Identity = 61/254 (24.02%), Postives = 107/254 (42.13%), Query Frame = 1

Query:  109 HNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSN--PFTPDT-----PVAEITLTRVEPQKDTQCVKTPVKGVNE-------------------FQNAQKESRSNTLGRNGAVEK--------------------------YNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCI---QLPRKEQKNCAGA 705
            H+  S+ + + PSPDW  GV+G++LC+  C W     + LYP D G  +G +Y  ++  ++  PD +R I   +   +  PF  DT     P+A + LTR +     +C + P +G  E                   + + Q+  ++  L  N   ++                            + + P    MA+  C  + W  WSPC+  CG G ++RTR+       + C+   ++P +E + C G+
Sbjct:  290 HHQISLAAKIDPSPDWILGVAGLELCLSNCTWLERKVLNLYPWDIGTDSGPSYMSSDEPQV-PPDVVRRITSSYPSDHRSPFYDDTGAPMKPLATLYLTRKK-LYIRECEEVPQEGPLECAVHPWNEWTNCSTRCGQGYSHRQRSFKNPNLAANFNCDRRLEEFRQCQGTQCGAAEEELEGEEPGLGMENPPSSGSMAE--CQLTNWGEWSPCTKTCGRGSSTRTRDYYNPQARQRCLSVMRIPLEETRECIGS 539

[Close]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Match: spon1b (spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10])

HSP 1 Score: 94.3597 bits (233), Expect = 1.177e-19
Identity = 72/251 (28.69%), Postives = 103/251 (41.04%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTP---VKGVNEFQNAQKESRSNTL---------------------GRNGAVEKYNVLDDPQL----------------AQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R  +L S ++M+GPSPDW  G+SG DLC   C W   L   L P DAG  +G +Y+  N   + + + IR +  +    +PF      P TP+  + + R+  +K  QC   P      V +    +KE   NT                      GR           DP L                ++   + C  SEW SWSPCS  CG G  SR R + +  ++     LP +E + C 
Sbjct:  297 SAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQ-ERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIA-RKGEQCNTVPDTIDDIVADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQDFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEETEKCV 545

HSP 2 Score: 53.5286 bits (127), Expect = 5.999e-7
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
             DC +SEWS W  C+KSCG G   + R+++ +   GGLPCP   + +KC  + C
Sbjct:  663 TDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKC 716

[Close]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Match: spon1b (spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10])

HSP 1 Score: 93.9745 bits (232), Expect = 1.358e-19
Identity = 72/251 (28.69%), Postives = 103/251 (41.04%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTP---VKGVNEFQNAQKESRSNTL---------------------GRNGAVEKYNVLDDPQL----------------AQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R  +L S ++M+GPSPDW  G+SG DLC   C W   L   L P DAG  +G +Y+  N   + + + IR +  +    +PF      P TP+  + + R+  +K  QC   P      V +    +KE   NT                      GR           DP L                ++   + C  SEW SWSPCS  CG G  SR R + +  ++     LP +E + C 
Sbjct:  297 SAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQ-ERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIA-RKGEQCNTVPDTIDDIVADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQDFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEETEKCV 545

HSP 2 Score: 53.1434 bits (126), Expect = 8.156e-7
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
             DC +SEWS W  C+KSCG G   + R+++ +   GGLPCP   + +KC  + C
Sbjct:  663 TDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKC 716

[Close]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Match: spon1b (spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10])

HSP 1 Score: 93.9745 bits (232), Expect = 1.398e-19
Identity = 72/251 (28.69%), Postives = 103/251 (41.04%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTP---VKGVNEFQNAQKESRSNTL---------------------GRNGAVEKYNVLDDPQL----------------AQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R  +L S ++M+GPSPDW  G+SG DLC   C W   L   L P DAG  +G +Y+  N   + + + IR +  +    +PF      P TP+  + + R+  +K  QC   P      V +    +KE   NT                      GR           DP L                ++   + C  SEW SWSPCS  CG G  SR R + +  ++     LP +E + C 
Sbjct:  260 SAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQ-ERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIA-RKGEQCNTVPDTIDDIVADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQDFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEETEKCV 508

HSP 2 Score: 53.1434 bits (126), Expect = 8.450e-7
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
             DC +SEWS W  C+KSCG G   + R+++ +   GGLPCP   + +KC  + C
Sbjct:  626 TDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKC 679

[Close]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Match: spon1b (spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10])

HSP 1 Score: 93.9745 bits (232), Expect = 1.433e-19
Identity = 72/251 (28.69%), Postives = 103/251 (41.04%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTP---VKGVNEFQNAQKESRSNTL---------------------GRNGAVEKYNVLDDPQL----------------AQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R  +L S ++M+GPSPDW  G+SG DLC   C W   L   L P DAG  +G +Y+  N   + + + IR +  +    +PF      P TP+  + + R+  +K  QC   P      V +    +KE   NT                      GR           DP L                ++   + C  SEW SWSPCS  CG G  SR R + +  ++     LP +E + C 
Sbjct:  297 SAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQ-ERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIA-RKGEQCNTVPDTIDDIVADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQDFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEETEKCV 545

HSP 2 Score: 53.1434 bits (126), Expect = 8.021e-7
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
             DC +SEWS W  C+KSCG G   + R+++ +   GGLPCP   + +KC  + C
Sbjct:  663 TDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKC 716

[Close]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Match: spon1a (spondin 1a [Source:ZFIN;Acc:ZDB-GENE-000427-9])

HSP 1 Score: 85.1149 bits (209), Expect = 8.189e-17
Identity = 68/250 (27.20%), Postives = 104/250 (41.60%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYK-PNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTLGRNGA---------------------------------VEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++M+GPSPDW  G+S  DLC   C W   +   L P DAG  +G +Y+ PN  T   E   IR +  +    +PF  P+    TPVA + + R+  +K  QC   P      V  + + +  + ++    +  N +                                  + +     P  +    + C  SEW +WSPCSV CG G  SR R + +   +      P +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMLGPSPDWNVGLSSEDLCTRECGWVQKVVQDLIPWDAGTDSGVSYESPNKSTAPQE--KIRPLTSLDHPQSPFYDPEGGAITPVARLVVERIA-RKGEQCNIVPDNVDDIVADIAQEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPHTQDFEPCMGPGCSDEDSSTCMMSEWITWSPCSVSCGSGLRSRERYVKQFPDDGFACTHPTEETEPC 548

[Close]

BLAST of Spondin-1 vs. Ensembl Xenopus
Match: spon1 (spondin 1, extracellular matrix protein [Source:NCBI gene;Acc:100036727])

HSP 1 Score: 86.6557 bits (213), Expect = 4.268e-17
Identity = 69/249 (27.71%), Postives = 103/249 (41.37%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTPVKG---VNEFQNAQKESR-----------------SNTLGRNGAVEKYNVLD-------------------DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+R+ +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + D IR +  +    +PF      P  PVA + + R+  +K  QC   P      V +    +KE                   S+     G   +  +L                     P  +    + C  SEW +WSPCS  CG G  SR R + +  ++    ++P +E + C
Sbjct:  298 SAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPSIPQ-DKIRPLTSLDHPQSPFYDPEGGPIIPVARVVIERIA-RKGDQCNIVPDNVDDIVPDLVTEEKEEDDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSVPCPDTQDFEPCMGPGCSDDEASTCMMSEWITWSPCSASCGMGMRSRERYVKQFPEDGSMCKVPTEETEKC 544

[Close]

BLAST of Spondin-1 vs. Ensembl Xenopus
Match: spon1 (spondin 1, extracellular matrix protein [Source:NCBI gene;Acc:100036727])

HSP 1 Score: 86.6557 bits (213), Expect = 4.293e-17
Identity = 69/249 (27.71%), Postives = 103/249 (41.37%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTPVKG---VNEFQNAQKESR-----------------SNTLGRNGAVEKYNVLD-------------------DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+R+ +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + D IR +  +    +PF      P  PVA + + R+  +K  QC   P      V +    +KE                   S+     G   +  +L                     P  +    + C  SEW +WSPCS  CG G  SR R + +  ++    ++P +E + C
Sbjct:  295 SAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPSIPQ-DKIRPLTSLDHPQSPFYDPEGGPIIPVARVVIERIA-RKGDQCNIVPDNVDDIVPDLVTEEKEEDDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSVPCPDTQDFEPCMGPGCSDDEASTCMMSEWITWSPCSASCGMGMRSRERYVKQFPEDGSMCKVPTEETEKC 541

[Close]

BLAST of Spondin-1 vs. Ensembl Xenopus
Match: spon1 (spondin 1, extracellular matrix protein [Source:NCBI gene;Acc:100036727])

HSP 1 Score: 83.1889 bits (204), Expect = 5.650e-16
Identity = 60/195 (30.77%), Postives = 87/195 (44.62%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPC-SVKCGEGETSRTRNLIKNL 648
            S   SV+R+ +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + D IR +  +    +PF      P  PVA + + R+  +K  QC   P                + +  +   E+    D P+        C +S W+ WS C S  C +G+  R R L   L
Sbjct:  298 SAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPSIPQ-DKIRPLTSLDHPQSPFYDPEGGPIIPVARVVIERIA-RKGDQCNIVP-------------DNVDDIVPDLVTEEKEEDDTPET-------CIYSNWSPWSACSSATCDKGKRMRQRMLKAQL 470

[Close]

BLAST of Spondin-1 vs. Ensembl Xenopus
Match: spon1 (spondin 1, extracellular matrix protein [Source:NCBI gene;Acc:100036727])

HSP 1 Score: 82.8037 bits (203), Expect = 6.330e-16
Identity = 60/195 (30.77%), Postives = 87/195 (44.62%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPC-SVKCGEGETSRTRNLIKNL 648
            S   SV+R+ +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + D IR +  +    +PF      P  PVA + + R+  +K  QC   P                + +  +   E+    D P+        C +S W+ WS C S  C +G+  R R L   L
Sbjct:  298 SAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPSIPQ-DKIRPLTSLDHPQSPFYDPEGGPIIPVARVVIERIA-RKGDQCNIVP-------------DNVDDIVPDLVTEEKEEDDTPET-------CIYSNWSPWSACSSATCDKGKRMRQRMLKAQL 470

[Close]

BLAST of Spondin-1 vs. Ensembl Xenopus
Match: spon1 (spondin 1, extracellular matrix protein [Source:NCBI gene;Acc:100036727])

HSP 1 Score: 82.8037 bits (203), Expect = 6.535e-16
Identity = 60/195 (30.77%), Postives = 87/195 (44.62%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPC-SVKCGEGETSRTRNLIKNL 648
            S   SV+R+ +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + D IR +  +    +PF      P  PVA + + R+  +K  QC   P                + +  +   E+    D P+        C +S W+ WS C S  C +G+  R R L   L
Sbjct:  305 SAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPSIPQ-DKIRPLTSLDHPQSPFYDPEGGPIIPVARVVIERIA-RKGDQCNIVP-------------DNVDDIVPDLVTEEKEEDDTPET-------CIYSNWSPWSACSSATCDKGKRMRQRMLKAQL 477

[Close]

BLAST of Spondin-1 vs. Ensembl Mouse
Match: Spon1 (spondin 1, (f-spondin) extracellular matrix protein [Source:MGI Symbol;Acc:MGI:2385287])

HSP 1 Score: 85.8853 bits (211), Expect = 5.470e-17
Identity = 69/249 (27.71%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESR--------------------SNTLGRNGAVEKYNVLD-------------------DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P    +   +   E +                    S++    G   +  +L                     P  +    + C  SEW +WSPCSV CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKC 548

HSP 2 Score: 57.3806 bits (137), Expect = 4.624e-8
Identity = 24/54 (44.44%), Postives = 35/54 (64.81%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC++SEWS W  C+KSCG G   + R IQ +   GG+PCP   + +KC ++ C
Sbjct:  667 IDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGVPCPETVQRKKCRTRKC 720

[Close]

BLAST of Spondin-1 vs. Ensembl Mouse
Match: Spon2 (spondin 2, extracellular matrix protein [Source:MGI Symbol;Acc:MGI:1923724])

HSP 1 Score: 73.9442 bits (180), Expect = 8.444e-14
Identity = 63/217 (29.03%), Postives = 97/217 (44.70%), Query Frame = 1

Query:   91 VSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDT-----------PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNLIKNLKNE--LCIQLPRKEQKNCA 699
            + V+  H+L S +  + PSPDW  G+  +DLC +G +WK  + + LYP DAG  +G T+   N   + + DT+ EI      S+P  P             P+A++T  R+  Q+  +    P        +    SR N +     V+  +V + P         C  S W+SW  C   CG+ G  SRTR +     N    C +L  +E+  CA
Sbjct:  139 LEVHPRHSLVSFVVRIVPSPDWFVGIDSLDLC-EGGRWKEQVVLDLYPHDAGTDSGFTFSSPNFATIPQ-DTVTEIT----ASSPSHPANSFYYPRLKSLPPIAKVTFVRL--QQSPRAFAPP--------SLDLASRGNEI-----VDSLSVPETP-------LDCEVSLWSSWGLCGGPCGKLGAKSRTRYVRVQPANNGTPCPEL--EEEAECA 325

[Close]

BLAST of Spondin-1 vs. Ensembl Mouse
Match: Spint2 (serine protease inhibitor, Kunitz type 2 [Source:MGI Symbol;Acc:MGI:1338031])

HSP 1 Score: 59.6918 bits (143), Expect = 1.790e-9
Identity = 36/135 (26.67%), Postives = 63/135 (46.67%), Query Frame = 1

Query:  982 RFFYHIKTGKCEPFKYYDCKKGNLNNFPT----IDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            R++Y+I  G C+PF Y  C+ GN NN+ +    +D C  V      ++ + R    + + +     + E LS +  N  E+C  +  +   C  + P+  WYY      C S +   C+G  N + + + CM+ C
Sbjct:   53 RWWYNITDGSCQPFVYGGCE-GNGNNYQSKEECLDKCAGVTENTTDDMARNRNGADSSVLSVPRKQSAEDLSAEIFNYEEYCVPKAVTGP-CRAAFPR--WYYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHC 183

[Close]

BLAST of Spondin-1 vs. Ensembl Mouse
Match: Tfpi (tissue factor pathway inhibitor [Source:MGI Symbol;Acc:MGI:1095418])

HSP 1 Score: 50.8322 bits (120), Expect = 1.356e-6
Identity = 37/132 (28.03%), Postives = 61/132 (46.21%), Query Frame = 1

Query:  985 FFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSS--KTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            +F+++ T +CE F Y  C+ GN N F T++ C+  C      +P   ++       + +  AE          P+FCF E D    +  MK      + Y+++ ++C+  V   C G  N F T D+C K C
Sbjct:   66 YFFNMYTHQCEEFIYGGCE-GNENRFDTLEECKKTC------IPGYEKT-----AVKAASGAER---------PDFCFLEEDPGLCRGYMKR-----YLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

[Close]

Query:  985 FFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSS--KTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            +F+++ T +CE F Y  C+ GN N F T++ C+  C      +P   ++       + +  AE          P+FCF E D    +  MK      + Y+++ ++C+  V   C G  N F T D+C K C
Sbjct:   66 YFFNMYTHQCEEFIYGGCE-GNENRFDTLEECKKTC------IPGYEKT-----AVKAASGAER---------PDFCFLEEDPGLCRGYMKR-----YLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

[Close]

BLAST of Spondin-1 vs. UniProt/SwissProt
Match: sp|P35446|SPON1_RAT (Spondin-1 OS=Rattus norvegicus OX=10116 GN=Spon1 PE=1 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 3.132e-16
Identity = 69/249 (27.71%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESR--------------------SNTLGRNGAVEKYNVLD-------------------DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P    +   +   E +                    S++    G   +  +L                     P  +    + C  SEW +WSPCSV CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKC 548

HSP 2 Score: 56.6102 bits (135), Expect = 5.560e-7
Identity = 24/54 (44.44%), Postives = 34/54 (62.96%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC++SEWS W  C+KSCG G   + R IQ +   GG PCP   + +KC ++ C
Sbjct:  667 IDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGAPCPETVQRKKCRARKC 720

[Close]

BLAST of Spondin-1 vs. UniProt/SwissProt
Match: sp|Q8VCC9|SPON1_MOUSE (Spondin-1 OS=Mus musculus OX=10090 GN=Spon1 PE=1 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 3.826e-16
Identity = 69/249 (27.71%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESR--------------------SNTLGRNGAVEKYNVLD-------------------DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P    +   +   E +                    S++    G   +  +L                     P  +    + C  SEW +WSPCSV CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKC 548

HSP 2 Score: 57.3806 bits (137), Expect = 3.235e-7
Identity = 24/54 (44.44%), Postives = 35/54 (64.81%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC++SEWS W  C+KSCG G   + R IQ +   GG+PCP   + +KC ++ C
Sbjct:  667 IDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGVPCPETVQRKKCRTRKC 720

[Close]

BLAST of Spondin-1 vs. UniProt/SwissProt
Match: sp|Q9GLX9|SPON1_BOVIN (Spondin-1 OS=Bos taurus OX=9913 GN=SPON1 PE=1 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 5.811e-16
Identity = 66/249 (26.51%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTLGRNGA---------------------------------VEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P      V  +   +  + ++    +  N +                                  + +     P  +    + C  SEW +WSPCS+ CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGTRSRERYVKQFPEDGSVCTLPTEETEKC 548

HSP 2 Score: 54.6842 bits (130), Expect = 2.238e-6
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC+++EWS W  C+KSCG G   + R+IQ +   GG PCP   + +KC  + C
Sbjct:  667 IDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKC 720

[Close]

BLAST of Spondin-1 vs. UniProt/SwissProt
Match: sp|Q9HCB6|SPON1_HUMAN (Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV=2)

HSP 1 Score: 85.1149 bits (209), Expect = 7.545e-16
Identity = 66/249 (26.51%), Postives = 104/249 (41.77%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTLGRNGA---------------------------------VEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNC 696
            S   SV+RT +L S ++MMGPSPDW  G+S  DLC   C W   +   L P DAG  +G TY+  N   + + + IR +  +    +PF  P+    T VA + + R+  +K  QC   P      V  +   +  + ++    +  N +                                  + +     P  +    + C  SEW +WSPCS+ CG G  SR R + +  ++     LP +E + C
Sbjct:  302 SAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQ-EKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIA-RKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKC 548

HSP 2 Score: 53.9138 bits (128), Expect = 3.380e-6
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC+++EWS W  C+KSCG G   + R+IQ +   GG PCP   + +KC  + C
Sbjct:  667 IDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKC 720

[Close]

BLAST of Spondin-1 vs. UniProt/SwissProt
Match: sp|Q9BUD6|SPON2_HUMAN (Spondin-2 OS=Homo sapiens OX=9606 GN=SPON2 PE=1 SV=3)

HSP 1 Score: 77.7962 bits (190), Expect = 2.875e-14
Identity = 61/199 (30.65%), Postives = 85/199 (42.71%), Query Frame = 1

Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDT-----------PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNL 636
            + S  + V R H+L S +  + PSPDW  GV  +DLC DG +W+    + LYP DAG  +G T+   N   + + DT+ EI      S+P  P             P+A +TL R+           PV            SR N +  + +V +   LD           C  S W+SW  C   CG  G  SRTR +
Sbjct:  135 QTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLC-DGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQ-DTVTEIT----SSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPV----------LPSRDNEIVDSASVPE-TPLD-----------CEVSLWSSWGLCGGHCGRLGTKSRTRYV 305

[Close]

BLAST of Spondin-1 vs. TrEMBL
Match: A0A0R3SRQ7 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS7882 PE=4 SV=1)

HSP 1 Score: 318.161 bits (814), Expect = 1.163e-93
Identity = 220/597 (36.85%), Postives = 291/597 (48.74%), Query Frame = 1

Query:   22 VKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEF------------------------------------QNAQKESRSNTLG---RNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTE-GKMIRIRKFARSKEKDEC---MKNVKPEII--LQQVKTCKLDKTDFRCDPISICSAG--KLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSY---SAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTI---WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV-----------------------------DCQVSEWSLWRPCSKSCG--WGTQYKKRVIQKDSLNGGLPCPVLYESRKC 1560
            ++SL ++  + GEE L E+R+   SVNRTH LFSM++M+GPSPDWCTG+SG  LC   C W  N+T+ L P DAGI+ G TY P    R D PD IR I++ WM  NPF  + PVA + + R+ P+ D +C      GV  F                                    +   K S+S   G    +G +   N L DP LAQMA   C  SEW++WS CSV CG G  +RTR LI N K ELC  +P   +++C G +  CD S  CS LPWS WSPC+A+C +  G   R R  AR KE  +C    K++   +   L +V+ C++      CDP +IC  G  +  PC  GK   R++Y      C  F+Y  CK G  N F T + CEN+C   ++ LP  RR  + LLQ +TS    SA ++ + + K  P  CF+EV++   C    PK I   WYY  R   C       C GT N+F     CM  C P+   +S  L KV                             DC+V+ W  W PCS  C    G QY+ R I + +  GG  C  LYE R C
Sbjct:  376 LRSLISTPGMWGEETLMEQRTTLFSVNRTHPLFSMLTMLGPSPDWCTGISGQSLCKADCTWVRNMTLYLRPWDAGIREGNTYMPKESDRKDIPDPIRYIDESWMPGNPFRENKPVARVEIERILPKNDWECTNVDADGVQLFVMGGGIRVSGKKVEEVKNKAADNMHTPSATQQIVTGKGRGKSSKSVGFGGPGSSGTLGTNNPLSDPSLAQMATFLCITSEWSAWSQCSVTCGVGTKTRTRELIANKKPELCQHVPLVMEESCEGRKRTCDYSAPCSFLPWSLWSPCNATCESPIGVRSRTRALARPKEAPQCEHLWKDLPGGMTSALNEVEECRIASEA--CDPATICGEGPKQGYPC--GKSMKRYYYSAIDHHCLEFEYLGCKGGR-NMFETREQCENICIPAVEALPAWRRERMGLLQFKTSQLSNSAADTCNMELKQDPA-CFYEVNTGYEC--DSPKEIGSYWYYYPRKNICSDFFYLGCGGTPNRFPNHTACMAACMPNDLRQSQILAKVRSNAGSNNPGELGDSEVPDGLEVAVSPKQDCRVTPWGGWGPCSTRCASQIGYQYRLRAIIRPARYGGEGCGPLYEKRNC 964

[Close]

BLAST of Spondin-1 vs. TrEMBL
Match: A0A5K3F8X7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 317.775 bits (813), Expect = 2.118e-93
Identity = 217/602 (36.05%), Postives = 292/602 (48.50%), Query Frame = 1

Query:   22 VKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNA----------QKESRSNTL---------------------------GRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASC-TTEGKMIRIRKFARSKEKDECM-------KNVKPEIILQQVKTCKLDKTDFRCDPISICSAG--KLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSY---SAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTI---WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV--------------------------------DCQVSEWSLWRPCSKSCG--WGTQYKKRVIQKDSLNGGLPCPVLYESRKCFS 1566
            ++SL T+  + GEE L EERS   SVNRTH L SM++M+GPSPDWCTG+SG  LC   C W +NLT+ LYP DAGI+ G TY P    R + PD IR I++ WM  NPF    PVA + + RV P+ D  C  T   GV  F+             KES  ++L                           G +G +   N L DP LAQMA   C   EW++WS CSV CG G  +RTR LI N K ELC  +P   +++C G +  CD S  CSLLPW+ WSPC+ +C +  G   R R  AR +E  +C        +  + + I+ +V+ C++      C+P +IC  G  +  PC  G    RF+Y     +C  F+Y  CK G  N F T   CE +C   ++ LP  RR  + LLQ +TS    S+ + L    K  P  C++EV++   C    PK +   WY+  R  +C+      C GT N+F+    CM  C P+    S  L KV                                DC+V++W  W PCS  C    G Q + R I++ S  GG  C  LYE R C+ 
Sbjct:  381 LRSLITTPGMWGEETLMEERSTLFSVNRTHPLVSMLTMLGPSPDWCTGISGQSLCKADCTWVNNLTLHLYPWDAGIREGNTYMPKESDRREIPDPIRYIDESWMPGNPFRERKPVAVVKIQRVRPKYDWACTNTDEDGVQLFKMGGGIYVTGKKNDKESDESSLKGGSATQQITAGKQKGKRTKSVGFGGPGASGTIGSNNPLSDPSLAQMATFLCITDEWSAWSACSVTCGVGTKTRTRRLIANKKPELCQHVPLVMEESCEGRKRTCDYSAPCSLLPWTLWSPCTGTCDSPRGHRSRKRALARPEEAAQCGHLWEGRNQEGREQGIMSEVEECQVPSET--CEPATICGEGPKQGYPC--GPKLRRFYYSAIDHECLEFEYLGCKGGR-NMFETKQDCEKLCIPAVEALPAWRRERMGLLQFKTSQLTSSSPDDLEDSLKRDP-VCYYEVNTGYEC--DPPKELGNYWYFCSRTNRCRDFFYLGCGGTPNRFANHTACMAACMPNELRHSQLLAKVRSATASRKAAANATDADEEAPDGLEVGVSPRQDCRVTQWGAWGPCSVRCSSQRGQQIRLRAIERPSRYGGEACGPLYERRSCYG 974

[Close]

BLAST of Spondin-1 vs. TrEMBL
Match: A0A0X3Q224 (Spondin-1 OS=Schistocephalus solidus OX=70667 GN=SPON1 PE=4 SV=1)

HSP 1 Score: 313.538 bits (802), Expect = 8.211e-93
Identity = 204/598 (34.11%), Postives = 288/598 (48.16%), Query Frame = 1

Query:   22 VKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQN-----------------------AQKESRSNT-------LGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKM-IRIRKFARSKEKDECMKNVKPEI------ILQQVKTCKLDKTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSY-----SAEESLSQKAKNIPEFCFHEVDSSKTC-MKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV----------------------------------------DCQVSEWSLWRPCSKSCG--WGTQYKKRVIQKDSLNGGLPCPVLYESRKC 1560
            + SL ++  + GEE LNE R+  ++VNRTH L S+++M+GPSPDWCTG+SG  +C   C W   L I LYP DAG++ G TY P N  RLD PD IR I++ WM  NPF    PVA +T+ R+ P+   QC      GV+ FQ                        +QK+ R           G +G++   + L DP LAQMA   C  S+W++W PCSV CG G   R R +I N K ELC  +    +++C G +  CD S  CSLLPW++WSPC+A+C +   +  R+RK   ++  +E   ++ P         L Q + C+L      CDP +IC  G       G+P   F+Y      C PF Y  CK G  N F + ++C+  C  V++ LP  RR  + LLQ +TS      + +ES     +N    C  EV++ + C    + ++ WYY  R  +C+  V   CKGT N+F+    CM  C P+    S +L ++                                        DCQV+ W  W PCS  C    G +++ R I + S  GG  C  LYE   C
Sbjct:  254 LHSLLSTPGMWGEETLNEPRTALIAVNRTHPLISLVTMLGPSPDWCTGISGQSVCKSDCTWVDKLEINLYPWDAGVRQGNTYMPKNADRLDIPDPIRYIDEKWMPGNPFYEHKPVARVTVQRILPEHAWQCTNRVADGVHLFQMGGTVMVSGKPANGSESVGAVQQVSQKKGRKGGKAVGFGGPGASGSLGTNDPLSDPSLAQMATFLCITSDWSAWGPCSVTCGVGSRKRQRTMISNKKPELCQHVQLTMEESCEGRQRTCDFSAPCSLLPWTAWSPCNATCQSPNHLGTRVRKRTLARRNEEGCDHLFPSARELATRTLVQTEECQLPPET--CDPATICGEGPKEGFPCGEPTPAFYYSAIEHDCLPFTYLGCKGGR-NRFSSAEACKTFCLPVVEALPAWRRERMGLLQFKTSQLSSTGATDESEGPVGQN--PACHEEVNTGEECDPPVEWESYWYYCPRTHRCRDFVYLGCKGTANRFTNHTACMAACMPNELRRSQQLARLRHSATKTSNMTGSEQKLQPEDNADFPVGLESMVDIANPKQDCQVTAWGAWGPCSAKCASEQGRRFRLRAILRPSRYGGKTCGPLYERTVC 846

[Close]

BLAST of Spondin-1 vs. TrEMBL
Match: A0A0R3U498 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS1462 PE=4 SV=2)

HSP 1 Score: 316.235 bits (809), Expect = 8.610e-93
Identity = 217/605 (35.87%), Postives = 292/605 (48.26%), Query Frame = 1

Query:   22 VKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNA----------QKESRSNTL------------------------------GRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASC-TTEGKMIRIRKFARSKEKDECM-------KNVKPEIILQQVKTCKLDKTDFRCDPISICSAG--KLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSY---SAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTI---WYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV--------------------------------DCQVSEWSLWRPCSKSCG--WGTQYKKRVIQKDSLNGGLPCPVLYESRKCFS 1566
            ++SL T+  + GEE L EERS   SVNRTH L SM++M+GPSPDWCTG+SG  LC   C W +NLT+ LYP DAGI+ G TY P    R + PD IR I++ WM  NPF    PVA + + RV P+ D  C  T   GV  F+             KES  ++L                              G +G +   N L DP LAQMA   C   EW++WS CSV CG G  +RTR LI N K ELC  +P   +++C G +  CD S  CSLLPW+ WSPC+ +C +  G   R R  AR +E  +C        +  + + I+ +V+ C++      C+P +IC  G  +  PC  G    RF+Y     +C  F+Y  CK G  N F T   CE +C   ++ LP  RR  + LLQ +TS    S+ + L    K  P  C++EV++   C    PK +   WY+  R  +C+      C GT N+F+    CM  C P+    S  L KV                                DC+V++W  W PCS  C    G Q + R I++ S  GG  C  LYE R C+ 
Sbjct:  381 LRSLITTPGMWGEETLMEERSTLFSVNRTHPLVSMLTMLGPSPDWCTGISGQSLCKADCTWVNNLTLHLYPWDAGIREGNTYMPKESDRREIPDPIRYIDESWMPGNPFRERKPVAVVKIQRVRPKYDWACTNTDEDGVQLFKMGGGIYVTGKKNDKESDESSLKEKAREQRCTTITAGKQKGKRTKSVGFGGPGASGTIGSNNPLSDPSLAQMATFLCITDEWSAWSACSVTCGVGTKTRTRRLIANKKPELCQHVPLVMEESCEGRKRTCDYSAPCSLLPWTLWSPCTGTCDSPRGHRSRKRALARPEEAAQCGHLWEGRNQEGREQGIMSEVEECQVPSET--CEPATICGEGPKQGYPC--GPKLRRFYYSAIDHECLEFEYLGCKGGR-NMFETKQDCEKLCIPAVEALPAWRRERMGLLQFKTSQLTSSSPDDLEDSLKRDP-VCYYEVNTGYEC--DPPKELGNYWYFCSRTNRCRDFFYLGCGGTPNRFANHTACMAACMPNELRHSQLLAKVRSATASRKAAANATDADEEAPDGLEVGVSPRQDCRVTQWGAWGPCSVRCSSQRGQQIRLRAIERPSRYGGEACGPLYERRSCYG 977

[Close]

BLAST of Spondin-1 vs. TrEMBL
Match: A0A0X3PKV3 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR92381 PE=4 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 4.459e-92
Identity = 204/598 (34.11%), Postives = 288/598 (48.16%), Query Frame = 1

Query:   22 VKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQN-----------------------AQKESRSNT-------LGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKM-IRIRKFARSKEKDECMKNVKPEI------ILQQVKTCKLDKTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSY-----SAEESLSQKAKNIPEFCFHEVDSSKTC-MKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKV----------------------------------------DCQVSEWSLWRPCSKSCG--WGTQYKKRVIQKDSLNGGLPCPVLYESRKC 1560
            + SL ++  + GEE LNE R+  ++VNRTH L S+++M+GPSPDWCTG+SG  +C   C W   L I LYP DAG++ G TY P N  RLD PD IR I++ WM  NPF    PVA +T+ R+ P+   QC      GV+ FQ                        +QK+ R           G +G++   + L DP LAQMA   C  S+W++W PCSV CG G   R R +I N K ELC  +    +++C G +  CD S  CSLLPW++WSPC+A+C +   +  R+RK   ++  +E   ++ P         L Q + C+L      CDP +IC  G       G+P   F+Y      C PF Y  CK G  N F + ++C+  C  V++ LP  RR  + LLQ +TS      + +ES     +N    C  EV++ + C    + ++ WYY  R  +C+  V   CKGT N+F+    CM  C P+    S +L ++                                        DCQV+ W  W PCS  C    G +++ R I + S  GG  C  LYE   C
Sbjct:  357 LHSLLSTPGMWGEETLNEPRTALIAVNRTHPLISLVTMLGPSPDWCTGISGQSVCKSDCTWVDKLEINLYPWDAGVRQGNTYMPKNADRLDIPDPIRYIDEKWMPGNPFYEHKPVARVTVQRILPEHAWQCTNRVADGVHLFQMGGTVMVSGKPANGSESVGAVQQVSQKKGRKGGKAVGFGGPGASGSLGTNDPLSDPSLAQMATFLCITSDWSAWGPCSVTCGVGSRKRQRTMISNKKPELCQHVQLTMEESCEGRQRTCDFSAPCSLLPWTAWSPCNATCQSPNHLGTRVRKRTLARRNEEGCDHLFPSARELATRTLVQTEECQLPPET--CDPATICGEGPKEGFPCGEPTPAFYYSAIEHDCLPFTYLGCKGGR-NRFSSAEACKTFCLPVVEALPAWRRERMGLLQFKTSQLSSTGATDESEGPVGQN--PACHEEVNTGEECDPPVEWESYWYYCPRTHRCRDFVYLGCKGTANRFTNHTACMAACMPNELRRSQQLARLRHSATKTSNMTGSEQKLQPEDNADFPVGLESMVDIANPKQDCQVTAWGAWGPCSAKCASEQGRRFRLRAILRPSRYGGKTCGPLYERTVC 949

[Close]

BLAST of Spondin-1 vs. Ensembl Cavefish
Match: spon1b (spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10])

HSP 1 Score: 92.8189 bits (229), Expect = 3.292e-19
Identity = 74/250 (29.60%), Postives = 106/250 (42.40%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYK-PNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVE--------------------PQKDTQCVKTPVKGVNEFQNAQKESRSNTL--GR-----------NGAVEKYNVLD-----DPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R H+L S ++M+GPSPDW  G+SG +LC   C W   L   L P DAG  +G TY+ PN  T   E   IR +  +    +PF      P TP+A + + R+                     P +DT+   TP   +    +      S+T   GR           +  V   +  D      P   +   + C  SEW SWSPCS  CG G  SR R + +  ++    + P +E + C 
Sbjct:  293 SAEFSVDRAHHLMSFLTMLGPSPDWNVGISGENLCTQECGWVQRLVKDLLPWDAGTDSGVTYESPNKPTNPQE--RIRPLTSLDHPQSPFYSPHGGPITPLARVVVERIARKGEQCNTVPDTVDDIVADIPPEDTEEDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDATVPCLHTQDFEPCMGPGCREEEPSTCMLSEWISWSPCSASCGMGMRSRERYIKQFPEDGSSCREPTEETEKCV 540

HSP 2 Score: 51.9878 bits (123), Expect = 1.686e-6
Identity = 22/54 (40.74%), Postives = 35/54 (64.81%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            VDC +S+WS W  C+KSCG G   + R+++ ++  GG+PCP   + +KC  + C
Sbjct:  658 VDCMLSDWSDWSECNKSCGKGHMIRSRMVKLEAQFGGVPCPETVQRKKCKIRKC 711

[Close]

BLAST of Spondin-1 vs. Ensembl Cavefish
Match: spon2b (spondin 2b, extracellular matrix protein [Source:ZFIN;Acc:ZDB-GENE-990415-161])

HSP 1 Score: 76.6406 bits (187), Expect = 9.596e-15
Identity = 65/237 (27.43%), Postives = 108/237 (45.57%), Query Frame = 1

Query:   19 NVKSLF-TSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNP----FTPDT----PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            +V  LF T   L+G  Q   E      V   H+  S I  + PSPDW  GV  ++LC +G  WK N+++ L+P DAG  +G T+   N   + + D + +I      S+P    + P      P+A++TLT++   K  Q    P+          + ++SN +     + + ++++ P         C  S W+ W  C  +CGE G   RTR +  +  N   +  P +++K C 
Sbjct:  135 SVYGLFSTPAVLDGTSQTTTE----FEVYARHSFLSFIMRLVPSPDWFVGVDSLNLC-EGDHWKENISLDLFPYDAGTDSGFTFSSPNFETIPQ-DKVMQITSS-FPSHPANSFYYPRLKHLPPIAKVTLTKI---KSNQIFSLPI----------EPTQSNQIPTGNEINE-SLINTP-------LDCEVSAWSPWGLCKGQCGEKGVRHRTRYIHIHPANNGAVCPPLEDEKPCV 343

[Close]

BLAST of Spondin-1 vs. Ensembl Cavefish
Match: spon2a (spondin-2-like [Source:NCBI gene;Acc:103039648])

HSP 1 Score: 61.6178 bits (148), Expect = 7.531e-10
Identity = 58/207 (28.02%), Postives = 86/207 (41.55%), Query Frame = 1

Query:  115 LFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYK--------PNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYN--VLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGET-SRTRNLIKNLKN--ELCIQLPRKEQKNC 696
            L S++  + PSPDW  GV  ++LC +G +WK  +T  L+P DAG  +G T+         P N+T +         N  +    P  P  P+A I L R          ++PV+  N   N       + L  +   +K++   LD           C  S W+SW  C   C  G    RTR ++    N    C +L  +EQ  C
Sbjct:  150 LLSLLVKVIPSPDWFVGVDSLNLC-EGGQWKQEVTFDLHPFDAGTDSGFTFSSPNFPTMPPENITMITSQKPNHPANSFYYPRLPQLP--PLATIWLRRQ--------ARSPVRQHNHVSN-------HILPHHTKPQKFSETPLD-----------CEVSMWSSWGLCLGPCSRGGLRHRTRYIMLKPANSGSPCPEL--EEQAEC 325

[Close]

BLAST of Spondin-1 vs. Ensembl Cavefish
Match: si:dkey-178e17.3 (somatomedin-B and thrombospondin type-1 domain-containing protein-like [Source:NCBI gene;Acc:103038119])

HSP 1 Score: 56.225 bits (134), Expect = 2.113e-8
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFS 1566
            +DC+V EW +W PCS  CG GT  + R +     NGG PCP L + R C +
Sbjct:   83 IDCEVGEWGVWSPCSSVCGAGTTERSRQVTTPPRNGGSPCPDLKQRRGCLA 133

[Close]

BLAST of Spondin-1 vs. Ensembl Cavefish
Match: thsd7ab (thrombospondin, type I, domain containing 7Ab [Source:ZFIN;Acc:ZDB-GENE-130530-999])

HSP 1 Score: 55.4546 bits (132), Expect = 1.591e-7
Identity = 28/53 (52.83%), Postives = 32/53 (60.38%), Query Frame = 1

Query: 1417 DCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            DC VS +S W  CSK+CG G Q + R I    L GGLPCP L E R C  +PC
Sbjct:  177 DCVVSRFSPWTACSKTCGLGLQNRVRSILAPPLFGGLPCPNLTEFRTCAPRPC 229

[Close]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Match: spon2b (spondin 2b, extracellular matrix protein [Source:ZFIN;Acc:ZDB-GENE-990415-161])

HSP 1 Score: 61.2326 bits (147), Expect = 1.627e-10
Identity = 64/221 (28.96%), Postives = 93/221 (42.08%), Query Frame = 1

Query:   22 VKSLFTSGWL-NGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETY-KPNNVTRLDEPDTIREINKIWMKSNPFTPD-----TPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSV-KCGE-GETSRTRNLIKNLKNE 657
            V  +F++  L NG  Q + E    +       L S++  + PSPDW  GV  ++LC +G +WK  L++ L P DAG  +G T+  PN  T   EP T    +     +N F         P+A + LTR+   K     K P   +   QN            +G   K   LD           C  ++W+ W  CSV  CG+ G   RTR +     N+
Sbjct:  101 VAGVFSAPALPNGTGQSSTE----LEFTAKQPLLSLMVRLVPSPDWFVGVDSLNLC-EGERWKERLSLDLQPYDAGTDSGFTFSSPNYATIPQEPITQMTSSSPSHPANSFYYPKLKQLPPLARLVLTRM--GKRPHSSKHPDANLVTRQNEPA---------SGVYIKQTPLD-----------CEVAKWSPWGLCSVDTCGQPGVKRRTRYIRVKPANQ 294

[Close]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Match: spon2a (spondin 2a, extracellular matrix protein [Source:ZFIN;Acc:ZDB-GENE-990415-160])

HSP 1 Score: 57.3806 bits (137), Expect = 6.837e-10
Identity = 26/68 (38.24%), Postives = 37/68 (54.41%), Query Frame = 1

Query: 1375 RPDS-QLESLKLDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            R DS Q E      +DC+VS+W+ W  CS++CG G +   R + +   NGG PCP L+    C  + C
Sbjct:  118 RSDSGQREEAAGTPLDCEVSDWAAWGFCSRTCGIGVKRSTRFVIQTPANGGRPCPELHMEESCVDRAC 185

HSP 2 Score: 48.9062 bits (115), Expect = 6.457e-7
Identity = 46/185 (24.86%), Postives = 72/185 (38.92%), Query Frame = 1

Query:  121 SMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETY-KPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGR-NGAVEKYNVLDDPQLAQMAKAF-----CGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKN 654
            S++  + PSPDW  GVS +DLC +   W   ++  L P D G  +G  +  PN  +   EP ++    +         P  P       R++          P  G  EF     +   +   R +  + K+  +      Q  +A      C  S+W +W  CS  CG G    TR +I+   N
Sbjct:    2 SIVVRLIPSPDWFVGVSSLDLCSNAGGWAPLVSHDLQPWDGGTDSGFAFSSPNYASEPQEPISLITAQR---------PSHPANSFYYPRLQ--------ALPRIGFLEF---HLQPADHAFQRPDDLICKHCQIVRSDSGQREEAAGTPLDCEVSDWAAWGFCSRTCGIGVKRSTRFVIQTPAN 166

[Close]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 3.222e-8
Identity = 39/133 (29.32%), Postives = 60/133 (45.11%), Query Frame = 1

Query:  982 RFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRS--NLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            R+F+++ +G CE F Y  C+ GNLNNF    SC   C      L   +RS         + +    ES S++   +P  C  + D  + C    P+  ++Y+ +   C+S     C G  N FS+   CM  C
Sbjct:   89 RYFFNMTSGSCEEFGYGGCQ-GNLNNFKDAASCYQHCVHRAVPLKIKKRSKQTNNNNNNKAARCNGESNSEQFV-LPRICLMKADPGE-CTAVIPR--FHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 216

[Close]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 3.781e-8
Identity = 39/133 (29.32%), Postives = 60/133 (45.11%), Query Frame = 1

Query:  982 RFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRS--NLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTC 1374
            R+F+++ +G CE F Y  C+ GNLNNF    SC   C      L   +RS         + +    ES S++   +P  C  + D  + C    P+  ++Y+ +   C+S     C G  N FS+   CM  C
Sbjct:   90 RYFFNMTSGSCEEFGYGGCQ-GNLNNFKDAASCYQHCVHRAVPLKIKKRSKQTNNNNNNKAARCNGESNSEQFV-LPRICLMKADPGE-CTAVIPR--FHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 217

[Close]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Match: si:dkey-178e17.3 (si:dkey-178e17.3 [Source:ZFIN;Acc:ZDB-GENE-081104-335])

HSP 1 Score: 46.9802 bits (110), Expect = 2.343e-6
Identity = 20/53 (37.74%), Postives = 28/53 (52.83%), Query Frame = 1

Query: 1411 KVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSK 1569
              DC V  W  W PCS +CG G++ + R +     NGG  CP L + + C+S 
Sbjct:    1 ATDCAVLGWGAWSPCSSACGVGSRERIRQVTVPPHNGGAKCPHLRQRQGCYSH 53

[Close]

BLAST of Spondin-1 vs. Ensembl Nematostella
Match: EDO49895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF43])

HSP 1 Score: 87.4261 bits (215), Expect = 9.741e-19
Identity = 78/249 (31.33%), Postives = 113/249 (45.38%), Query Frame = 1

Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKMIRIRKFAR 822
            E S    V+ T +L SMIS M PSPDW  GV  ++LC   C WK   TI L P DAG   G T+K  N                       TP  P++ IT TR+               +  F + + E  + + G +   + +    +P   + A+  C  + W+ W+ CSV CG GE  R R++I+  +++        E + C  AR  C  +KKC + PWS+WS C  SC   G+ +R R+  R
Sbjct:   97 ESSAVFRVDSTRHLLSMISRMIPSPDWNVGVDRVNLCTTNCTWKHEETIDLIPWDAGTDDGITFKSPNARS--------------------TPKQPISRIT-TRLHDHPRASFYLNTNDQIRPFASLKLERLAVSGGCSN--DAHIAPKNPYPPKSARIDCQLTHWSKWTSCSVTCGVGEQIRGRDIIRVPEHDGIPCPNLYEHRPC--ARQRCSSTKKCEVTPWSAWSSCRGSCGV-GRKVRTRRIIR 319

HSP 2 Score: 55.4546 bits (132), Expect = 2.527e-8
Identity = 25/58 (43.10%), Postives = 35/58 (60.34%), Query Frame = 1

Query: 1402 KLDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            K  ++DCQ++ WS W  CS +CG G Q + R I +   + G+PCP LYE R C  + C
Sbjct:  228 KSARIDCQLTHWSKWTSCSVTCGVGEQIRGRDIIRVPEHDGIPCPNLYEHRPCARQRC 285

[Close]

BLAST of Spondin-1 vs. Ensembl Nematostella
Match: EDO47504 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLY4])

HSP 1 Score: 52.373 bits (124), Expect = 1.884e-7
Identity = 30/63 (47.62%), Postives = 36/63 (57.14%), Query Frame = 1

Query: 1393 ESLKLDKV-DCQVSEWSLWRPCSKSCGWGTQYK-KRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            E  KL  V DC VS WS W PCS  CG G + + +RVI + S  GG  CP L + R CF + C
Sbjct:   83 EECKLQGVQDCVVSTWSRWSPCSHRCGVGMRKRSRRVIVRPSQRGGKECPPLRQKRGCFLEHC 145

[Close]

BLAST of Spondin-1 vs. Ensembl Medaka
Match: spon1b (spondin-1 [Source:NCBI gene;Acc:101161803])

HSP 1 Score: 89.7373 bits (221), Expect = 2.678e-18
Identity = 69/255 (27.06%), Postives = 104/255 (40.78%), Query Frame = 1

Query:   67 LNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-----TPDTPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTL-----------------GRN----------------GAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            L    S   SV+R  +L S ++M+GPSPDW  G+SG DLC   C W   L   L P DAG  +G TY+  N   + + D IR +       +PF      P +P+A + + R+  +K  QC   P      V  + + +  + ++    +                 GR                    + +     P  +    + C  SEW SWS CSV CG G  SR R + +  ++    QL  +E + C 
Sbjct:  289 LRAAPSAEFSVDRARHLMSFLTMLGPSPDWNVGLSGEDLCTKDCGWIQRLVADLIPWDAGTDSGVTYESPNKPTIPQ-DKIRPLTSFDHPQSPFYDPQGGPISPLARVVVERIA-RKGEQCNVVPDNIDDIVADIGQEEKEEDDTPETCIYSAWSPWSACSSATCDKGRRMRQRMLKAQLDLSVPCPHTQDFQPCMAPGCSMEEPSTCMMSEWISWSACSVSCGMGMRSRERYVKQYPEDGSLCQLHTEETEKCV 541

HSP 2 Score: 50.447 bits (119), Expect = 5.317e-6
Identity = 25/70 (35.71%), Postives = 41/70 (58.57%), Query Frame = 1

Query: 1372 CRPDSQLESLKLDK--VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            CR +++ +  +L +  +DC VSEWS W  C+KSCG G   + R+++ +   GG  CP   + +KC  + C
Sbjct:  640 CREETEQKECRLPECSIDCMVSEWSEWSECNKSCGKGHTIRTRMVKLEPQFGGRACPETIQRKKCKLRKC 709

[Close]

BLAST of Spondin-1 vs. Ensembl Medaka
Match: spon1a (spondin 1 [Source:NCBI gene;Acc:101161963])

HSP 1 Score: 85.8853 bits (211), Expect = 4.013e-17
Identity = 65/250 (26.00%), Postives = 106/250 (42.40%), Query Frame = 1

Query:   82 SGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPF-TPD----TPVAEITLTRVEPQKDTQCVKTP------VKGVNEFQNAQKESRSNTLGRNGA---------------------------------VEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCA 699
            S   SV+R  +L S ++MMGPSPDW  G+S  +LC   C W   +   L P DAG  +G +Y+ +N   + + + IR +  +    +PF  P+    TPVA + + R+  +K  QC   P      V  + + +  + ++    +  N +                                  + +     P  +    + C  SEW +WSPCS+ CG G  SR R + +   +     LP +E +NC 
Sbjct:  300 SAEFSVDRIRHLMSFLTMMGPSPDWNVGLSAENLCTKECGWVQKVVQDLIPWDAGTDSGVSYESSNKPTVPQ-EKIRPLTSLDHPQSPFYDPEGGAITPVARVVVERIA-RKGEQCNIVPDNVDDIVADIAQEEKEEDDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPHTQDFEPCMGPGCSDEDGSTCMMSEWITWSPCSMSCGAGIRSRERYVKQFPDDGSICTLPTEETENCV 547

[Close]

BLAST of Spondin-1 vs. Ensembl Medaka
Match: spon2b (spondin 2 [Source:NCBI gene;Acc:101164320])

HSP 1 Score: 78.9518 bits (193), Expect = 1.538e-15
Identity = 64/211 (30.33%), Postives = 102/211 (48.34%), Query Frame = 1

Query:   49 LNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNP----FTPDT----PVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGE-GETSRTRNLIKNLKN 654
            + G  Q++ E   F      H+L S +  + PSPDW  GV  I+LC +G KWK ++T+ L+P DAG  +G T+   N   + + D I +I   +  S+P    F P      P+A++ LT++  +K  Q +  P+          + ++SN L     +E+  +++ P         C  S W+ W  C  KCGE G   RTR +I +  N
Sbjct:  135 VGGTGQMDTEFEVFAR----HSLMSFMVRIIPSPDWFVGVDSINLC-NGDKWKESVTLELFPYDAGTDSGFTFSSPNFETIPQ-DRITQITSSY-PSHPANSFFYPRLKHLPPIAKVKLTKI--KKTNQIISLPM----------EPTQSNLLPTGNEIEE-TLINTP-------LDCEVSVWSPWGLCKGKCGESGVQHRTRYVIMHPAN 318

HSP 2 Score: 50.0618 bits (118), Expect = 3.768e-6
Identity = 25/62 (40.32%), Postives = 33/62 (53.23%), Query Frame = 1

Query: 1393 ESLKLDKVDCQVSEWSLWRPCSKSCG-WGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            E+L    +DC+VS WS W  C   CG  G Q++ R +     N G+ CP+L E RKC    C
Sbjct:  276 ETLINTPLDCEVSVWSPWGLCKGKCGESGVQHRTRYVIMHPANNGVACPLLEEERKCIPDNC 337

[Close]

BLAST of Spondin-1 vs. Ensembl Medaka
Match: spon2a (spondin-2 [Source:NCBI gene;Acc:101163419])

HSP 1 Score: 55.0694 bits (131), Expect = 1.025e-7
Identity = 61/226 (26.99%), Postives = 96/226 (42.48%), Query Frame = 1

Query:   37 TSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETY-KPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKES-RSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGET-SRTRNLIKNLKN--ELCIQLPRKEQKNCA 699
            T+G  NG    + E    V +    +L S++  M PSPDW  GV+ ++LC +G  WK  +T+ L P DAG  +G T+  P   T    P+ I +I           P+ P       R+   K+   + + +K   + ++A +++  SN +  N           P+        C  S W+SW  C   C  G    RTR ++    N    C +L  +EQ  C 
Sbjct:  128 TAGIPNGIGHSSTE----VHMQPRSSLLSLMVKMIPSPDWFVGVNSLNLC-EGNHWKQEVTVNLQPYDAGTNSGFTFSSPKFPT--SPPENISKITSQ-------VPNHPANSFYYPRL---KELPAIAS-IKITRQHRSANRQTVLSNHILPNSI--------SPRRFSETPLDCEVSLWSSWGLCLGPCSRGGIRHRTRYILLRPANAGSPCPEL--EEQAECV 325

[Close]

BLAST of Spondin-1 vs. Ensembl Medaka
Match: si:dkey-178e17.3 (somatomedin-B and thrombospondin type-1 domain-containing protein [Source:NCBI gene;Acc:101155034])

HSP 1 Score: 48.521 bits (114), Expect = 6.958e-6
Identity = 19/55 (34.55%), Postives = 28/55 (50.91%), Query Frame = 1

Query: 1402 KLDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFS 1566
            ++  +DC V  W  W  C+  CG G+  + R +     NGG PCP L + R C+ 
Sbjct:   51 QISAIDCVVGSWGAWSLCTSKCGVGSTERSRQVSVPPRNGGAPCPDLRQRRGCYG 105

[Close]

BLAST of Spondin-1 vs. Planmine SMEST
Match: SMESG000009946.1 (SMESG000009946.1)

HSP 1 Score: 385.185 bits (988), Expect = 2.211e-124
Identity = 220/532 (41.35%), Postives = 305/532 (57.33%), Query Frame = 1

Query:   19 NVKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEF--QNAQKESRSNTLG-----RNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLDKTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEF---CFHEVD-SSKTCMKSK-PKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKVD-CQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            ++KS F +  +  E+++ + RSGF+SVNRTH+ FS ++MMGPSPDWCTGV+ +D+CM+ C WK + T+ L+P DAGI+ G TY P N  R D PD IR IN  +M   PFT + PVA +   +++P+ + +C K   K V EF   N+ K   S   G     +   + K + LDDP LA MA   C  S W+ W+ CSV CG G   R+R+++KN K ELC  LP  E + C G +  CD S  CSLL WS W PC+A+C   G   R R FAR +EK++C+KN +    + + K CK D     CDP+ ICS G +     GKP  ++FY      C PF+Y  C KG+LNNFP+  SCE  C   +  LP+ R+  +A LQ ++     +S S K K +P     C  EV      C  +  P   +YY +RN +C+      C G  N F ++  C+K C PD Q++ +K   +  CQVSEWS W PCS +CG G ++K R + + +LNGG  CP L+ S  CF+  C
Sbjct:  262 HLKSYFNTSGMWNEDEIEQSRSGFISVNRTHHFFSFLTMMGPSPDWCTGVAAVDMCMNDCTWKDDFTMDLFPFDAGIKNGFTYFPENSDRQDIPDPIRTINTTYMTQFPFTANVPVARVIYQKIKPKHNWECTKMNAKQVKEFDEMNSNKNGNSQFDGSSLTKKRRHINKKSPLDDPTLANMATFLCITSPWSEWTKCSVTCGIGTEMRSRDMLKNAKTELCRHLPLLESRTCEGRKRSCDFSAPCSLLSWSRWGPCNATCEMHGYQQRSRMFARFEEKEKCLKNKERRFKIFEEKRCKKDTA--LCDPVIICSEGLIMGSSCGKPVMKYFYDAAKHSCVPFEYLGC-KGSLNNFPSKMSCEKTCLAAVNALPQWRKDKMAHLQFQS-----QSNSDKRKKMPTMANKCRLEVKYGGMNCDGTMGPDIRYYYDNRNGRCRQFKYTGCDGNSNNFRSYHSCIKACMPD-QIDFMKTAPIKACQVSEWSHWGPCSTTCGVGERFKWRSVLRPALNGGPACPELFLSEPCFATTC 784

[Close]

BLAST of Spondin-1 vs. Planmine SMEST
Match: SMESG000009946.1 (SMESG000009946.1)

HSP 1 Score: 385.571 bits (989), Expect = 2.515e-124
Identity = 221/533 (41.46%), Postives = 306/533 (57.41%), Query Frame = 1

Query:   19 NVKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQ--------NAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLDKTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEF---CFHEVD-SSKTCMKSK-PKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKVD-CQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            ++KS F +  +  E+++ + RSGF+SVNRTH+ FS ++MMGPSPDWCTGV+ +D+CM+ C WK + T+ L+P DAGI+ G TY P N  R D PD IR IN  +M   PFT + PVA +   +++P+ + +C K   K V EF         N+Q +  S T  R   + K + LDDP LA MA   C  S W+ W+ CSV CG G   R+R+++KN K ELC  LP  E + C G +  CD S  CSLL WS W PC+A+C   G   R R FAR +EK++C+KN +    + + K CK D     CDP+ ICS G +     GKP  ++FY      C PF+Y  C KG+LNNFP+  SCE  C   +  LP+ R+  +A LQ ++     +S S K K +P     C  EV      C  +  P   +YY +RN +C+      C G  N F ++  C+K C PD Q++ +K   +  CQVSEWS W PCS +CG G ++K R + + +LNGG  CP L+ S  CF+  C
Sbjct:  278 HLKSYFNTSGMWNEDEIEQSRSGFISVNRTHHFFSFLTMMGPSPDWCTGVAAVDMCMNDCTWKDDFTMDLFPFDAGIKNGFTYFPENSDRQDIPDPIRTINTTYMTQFPFTANVPVARVIYQKIKPKHNWECTKMNAKQVKEFDEMNSNKNGNSQFDGSSLTKKRR-HINKKSPLDDPTLANMATFLCITSPWSEWTKCSVTCGIGTEMRSRDMLKNAKTELCRHLPLLESRTCEGRKRSCDFSAPCSLLSWSRWGPCNATCEMHGYQQRSRMFARFEEKEKCLKNKERRFKIFEEKRCKKDTA--LCDPVIICSEGLIMGSSCGKPVMKYFYDAAKHSCVPFEYLGC-KGSLNNFPSKMSCEKTCLAAVNALPQWRKDKMAHLQFQS-----QSNSDKRKKMPTMANKCRLEVKYGGMNCDGTMGPDIRYYYDNRNGRCRQFKYTGCDGNSNNFRSYHSCIKACMPD-QIDFMKTAPIKACQVSEWSHWGPCSTTCGVGERFKWRSVLRPALNGGPACPELFLSEPCFATTC 800

[Close]

BLAST of Spondin-1 vs. Planmine SMEST
Match: SMESG000009946.1 (SMESG000009946.1)

HSP 1 Score: 385.185 bits (988), Expect = 4.790e-124
Identity = 220/532 (41.35%), Postives = 305/532 (57.33%), Query Frame = 1

Query:   19 NVKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEF--QNAQKESRSNTLG-----RNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLDKTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEF---CFHEVD-SSKTCMKSK-PKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQLESLKLDKVD-CQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            ++KS F +  +  E+++ + RSGF+SVNRTH+ FS ++MMGPSPDWCTGV+ +D+CM+ C WK + T+ L+P DAGI+ G TY P N  R D PD IR IN  +M   PFT + PVA +   +++P+ + +C K   K V EF   N+ K   S   G     +   + K + LDDP LA MA   C  S W+ W+ CSV CG G   R+R+++KN K ELC  LP  E + C G +  CD S  CSLL WS W PC+A+C   G   R R FAR +EK++C+KN +    + + K CK D     CDP+ ICS G +     GKP  ++FY      C PF+Y  C KG+LNNFP+  SCE  C   +  LP+ R+  +A LQ ++     +S S K K +P     C  EV      C  +  P   +YY +RN +C+      C G  N F ++  C+K C PD Q++ +K   +  CQVSEWS W PCS +CG G ++K R + + +LNGG  CP L+ S  CF+  C
Sbjct:  285 HLKSYFNTSGMWNEDEIEQSRSGFISVNRTHHFFSFLTMMGPSPDWCTGVAAVDMCMNDCTWKDDFTMDLFPFDAGIKNGFTYFPENSDRQDIPDPIRTINTTYMTQFPFTANVPVARVIYQKIKPKHNWECTKMNAKQVKEFDEMNSNKNGNSQFDGSSLTKKRRHINKKSPLDDPTLANMATFLCITSPWSEWTKCSVTCGIGTEMRSRDMLKNAKTELCRHLPLLESRTCEGRKRSCDFSAPCSLLSWSRWGPCNATCEMHGYQQRSRMFARFEEKEKCLKNKERRFKIFEEKRCKKDTA--LCDPVIICSEGLIMGSSCGKPVMKYFYDAAKHSCVPFEYLGC-KGSLNNFPSKMSCEKTCLAAVNALPQWRKDKMAHLQFQS-----QSNSDKRKKMPTMANKCRLEVKYGGMNCDGTMGPDIRYYYDNRNGRCRQFKYTGCDGNSNNFRSYHSCIKACMPD-QIDFMKTAPIKACQVSEWSHWGPCSTTCGVGERFKWRSVLRPALNGGPACPELFLSEPCFATTC 807

[Close]

BLAST of Spondin-1 vs. Planmine SMEST
Match: SMESG000039905.1 (SMESG000039905.1)

HSP 1 Score: 152.525 bits (384), Expect = 1.213e-38
Identity = 148/521 (28.41%), Postives = 219/521 (42.03%), Query Frame = 1

Query:   76 ERSGFVSVNRTHNLFSMISMMGPSPDWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEPDTIREINKIWMKSNPFT------PDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQNAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVKCGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLXXXXXXXXXXXXXXXXASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLDKTDFRCDPISICSAGKLA--PCINGKPKTRFFYHIKTGKCEPFKYYDCKKGNLNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKNIPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFSTFDDCMKTCRPDSQL--------ESLKLDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCP-VLYESRKCFSKPC*SVN 1587
            +RS  + VN T +L S ++ + PSPDWCTG+S  DLC   CKW+    + LYP DAG+ +GETY   N      P  I  I   W K NPFT       +  V    L +   + D Q   + +  + + +  Q E +S+ L  N    ++ +L +                         CG+GE +R R L+K  K+E CI+      ++C+         + CS   W  WSPC+A+C+ +G + R R F   +EK ECM+  + +  L+    C L     RC P  IC         C    P  RF+Y   +G C  F Y  C  G LNNF T + C  +C       PK++ ++        +Y             P  C   +     C    P   WYY + N++C       C+G  N F T  +C   C  +           + + + KV C  S WS W  C  +C       + +I+K+       C   + E+RKC S+ C S N
Sbjct:  308 KRSALIVVNATQHLVSFLARLHPSPDWCTGLSRFDLCNGSCKWQEKFIVHLYPWDAGVYSGETYLNKNEKTRQTP--ICPITSSWPKDNPFTVMNGKIKNIGVVTFQLIQEYNKNDNQYCNS-INSILQDEAYQNEPKSSALKSNPDKTRHCLLSEWSEWSSCSE---------------SCGKGEKTRYRKLLKG-KSEQCIESSLTNTESCSSKCSTAISFETCSFRLWGQWSPCNATCSQKGIIHRERVFINEQEKHECMQYSEMKASLE----CALASE--RCKPDVICKEYVYPGDSCSWSSPSQRFYYDFSSGTCNAFIYKGC-YGGLNNFHTYEECILLCR------PKLKETDQRRFNTPETY-------------PNRCGVSMTWGIFCDSQSPSNRWYYDNINKECYRFRFGGCRGNANNFRTKTECQNVCLREKSTSTTTTTISQPVTVRKV-CIYSNWSDWSSCDDNCQNQQTRIRFLIEKND-----DCTESISETRKCQSEKCNSPN 777

[Close]

BLAST of Spondin-1 vs. Planmine SMEST
Match: SMESG000076582.1 (SMESG000076582.1)

HSP 1 Score: 52.7582 bits (125), Expect = 8.155e-7
Identity = 22/54 (40.74%), Postives = 36/54 (66.67%), Query Frame = 1

Query: 1414 VDCQVSEWSLWRPCSKSCGWGTQYKKRVIQKDSLNGGLPCPVLYESRKCFSKPC 1575
            +DC+VSEW+ W  CSK+CG G   + R+I K ++  G     L+E+++C++ PC
Sbjct: 5605 IDCEVSEWTSWSSCSKTCGVGRYTRTRIIVKAAMFNGNCEDPLFETQQCYNGPC 5658

The following BLAST results are available for this feature:

BLAST of Spondin-1 vs. Ensembl Human
BLAST of Spondin-1 vs. Ensembl Celegans
BLAST of Spondin-1 vs. Ensembl Fly
BLAST of Spondin-1 vs. Ensembl Zebrafish
BLAST of Spondin-1 vs. Ensembl Xenopus
BLAST of Spondin-1 vs. Ensembl Mouse
BLAST of Spondin-1 vs. UniProt/SwissProt
BLAST of Spondin-1 vs. TrEMBL
BLAST of Spondin-1 vs. Ensembl Cavefish
BLAST of Spondin-1 vs. Ensembl Sea Lamprey
BLAST of Spondin-1 vs. Ensembl Yeast
BLAST of Spondin-1 vs. Ensembl Nematostella
BLAST of Spondin-1 vs. Ensembl Medaka
BLAST of Spondin-1 vs. Planmine SMEST

BLAST of Spondin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SPON1	1.571e-16	26.51	spondin 1 [Source:HGNC Symbol;Acc:HGNC:11252]	[more]
SPON2	7.885e-15	30.65	spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253]	[more]
SPON2	7.885e-15	30.65	spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253]	[more]
SPON2	7.885e-15	30.65	spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253]	[more]
TFPI	4.619e-7	26.43	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]

BLAST of Spondin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon-1	2.486e-24	28.82	SPONdin (Extracellular matrix glycoprotein) family...	[more]
E01G6.1	4.243e-11	30.57	pep chromosome:WBcel235:X:12260881:12266537:1 gene...	[more]
K10D3.4	8.067e-9	27.74	pep chromosome:WBcel235:I:7134738:7139973:-1 gene:...	[more]
mlt-11	7.845e-7	29.37	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	8.210e-7	29.37	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]

BLAST of Spondin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fat-spondin	1.004e-19	32.02	gene:FBgn0026721 transcript:FBtr0086975	[more]
CG30046	1.543e-19	28.20	gene:FBgn0050046 transcript:FBtr0087895	[more]
CG30046	1.543e-19	28.20	gene:FBgn0050046 transcript:FBtr0339627	[more]
CG17739	9.681e-19	28.51	gene:FBgn0033710 transcript:FBtr0087893	[more]
CG30203	9.548e-16	24.02	gene:FBgn0050203 transcript:FBtr0273303	[more]

BLAST of Spondin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon1b	1.177e-19	28.69	spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10]	[more]
spon1b	1.358e-19	28.69	spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10]	[more]
spon1b	1.398e-19	28.69	spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10]	[more]
spon1b	1.433e-19	28.69	spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10]	[more]
spon1a	8.189e-17	27.20	spondin 1a [Source:ZFIN;Acc:ZDB-GENE-000427-9]	[more]

BLAST of Spondin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon1	4.268e-17	27.71	spondin 1, extracellular matrix protein [Source:NC...	[more]
spon1	4.293e-17	27.71	spondin 1, extracellular matrix protein [Source:NC...	[more]
spon1	5.650e-16	30.77	spondin 1, extracellular matrix protein [Source:NC...	[more]
spon1	6.330e-16	30.77	spondin 1, extracellular matrix protein [Source:NC...	[more]
spon1	6.535e-16	30.77	spondin 1, extracellular matrix protein [Source:NC...	[more]

BLAST of Spondin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Spon1	5.470e-17	27.71	spondin 1, (f-spondin) extracellular matrix protei...	[more]
Spon2	8.444e-14	29.03	spondin 2, extracellular matrix protein [Source:MG...	[more]
Spint2	1.790e-9	26.67	serine protease inhibitor, Kunitz type 2 [Source:M...	[more]
Tfpi	1.356e-6	28.03	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	1.356e-6	28.03	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]

BLAST of Spondin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P35446\|SPON1_RAT	3.132e-16	27.71	Spondin-1 OS=Rattus norvegicus OX=10116 GN=Spon1 P...	[more]
sp\|Q8VCC9\|SPON1_MOUSE	3.826e-16	27.71	Spondin-1 OS=Mus musculus OX=10090 GN=Spon1 PE=1 S...	[more]
sp\|Q9GLX9\|SPON1_BOVIN	5.811e-16	26.51	Spondin-1 OS=Bos taurus OX=9913 GN=SPON1 PE=1 SV=1	[more]
sp\|Q9HCB6\|SPON1_HUMAN	7.545e-16	26.51	Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV...	[more]
sp\|Q9BUD6\|SPON2_HUMAN	2.875e-14	30.65	Spondin-2 OS=Homo sapiens OX=9606 GN=SPON2 PE=1 SV...	[more]

BLAST of Spondin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0R3SRQ7	1.163e-93	36.85	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A5K3F8X7	2.118e-93	36.05	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A0X3Q224	8.211e-93	34.11	Spondin-1 OS=Schistocephalus solidus OX=70667 GN=S...	[more]
A0A0R3U498	8.610e-93	35.87	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A0X3PKV3	4.459e-92	34.11	Uncharacterized protein OS=Schistocephalus solidus...	[more]

BLAST of Spondin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon1b	3.292e-19	29.60	spondin 1b [Source:ZFIN;Acc:ZDB-GENE-000427-10]	[more]
spon2b	9.596e-15	27.43	spondin 2b, extracellular matrix protein [Source:Z...	[more]
spon2a	7.531e-10	28.02	spondin-2-like [Source:NCBI gene;Acc:103039648]	[more]
si:dkey-178e17.3	2.113e-8	45.10	somatomedin-B and thrombospondin type-1 domain-con...	[more]
thsd7ab	1.591e-7	52.83	thrombospondin, type I, domain containing 7Ab [Sou...	[more]

BLAST of Spondin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon2b	1.627e-10	28.96	spondin 2b, extracellular matrix protein [Source:Z...	[more]
spon2a	6.837e-10	38.24	spondin 2a, extracellular matrix protein [Source:Z...	[more]
ENSPMAT00000005043.1	3.222e-8	29.32	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005038.1	3.781e-8	29.32	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
si:dkey-178e17.3	2.343e-6	37.74	si:dkey-178e17.3 [Source:ZFIN;Acc:ZDB-GENE-081104-...	[more]

BLAST of Spondin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Spondin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO49895	9.741e-19	31.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47504	1.884e-7	47.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Spondin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spon1b	2.678e-18	27.06	spondin-1 [Source:NCBI gene;Acc:101161803]	[more]
spon1a	4.013e-17	26.00	spondin 1 [Source:NCBI gene;Acc:101161963]	[more]
spon2b	1.538e-15	30.33	spondin 2 [Source:NCBI gene;Acc:101164320]	[more]
spon2a	1.025e-7	26.99	spondin-2 [Source:NCBI gene;Acc:101163419]	[more]
si:dkey-178e17.3	6.958e-6	34.55	somatomedin-B and thrombospondin type-1 domain-con...	[more]

BLAST of Spondin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000009946.1	2.211e-124	41.35	SMESG000009946.1	[more]
SMESG000009946.1	2.515e-124	41.46	SMESG000009946.1	[more]
SMESG000009946.1	4.790e-124	41.35	SMESG000009946.1	[more]
SMESG000039905.1	1.213e-38	28.41	SMESG000039905.1	[more]
SMESG000076582.1	8.155e-7	40.74	SMESG000076582.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30032088 ID=SMED30032088|Name=Spondin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1776bp
TTACCTGAAAATAGATTAAATGTTAAGAGTCTCTTTACGTCAGGCTGGTT
AAATGGGGAAGAACAGCTAAATGAAGAGCGTTCTGGATTCGTTTCTGTTA
ATAGAACTCATAATTTATTTAGTATGATTTCAATGATGGGACCAAGTCCG
GATTGGTGTACCGGAGTGTCAGGAATCGATCTTTGTATGGACGGATGCAA
ATGGAAATCAAATCTAACAATTCCTCTTTATCCTATCGACGCTGGAATAC
AAACTGGAGAGACCTACAAACCAAATAATGTCACAAGACTTGATGAACCC
GACACTATTAGAGAAATTAATAAAATTTGGATGAAAAGTAATCCTTTTAC
TCCAGATACTCCAGTAGCAGAAATCACCCTCACCAGAGTAGAGCCACAGA
AAGACACACAATGTGTTAAAACTCCAGTTAAGGGTGTAAATGAATTTCAA
AATGCACAAAAAGAGTCTAGATCTAACACGCTCGGTAGAAATGGTGCCGT
GGAAAAATATAATGTTCTAGATGATCCTCAGTTAGCTCAAATGGCAAAAG
CCTTTTGTGGATTTTCCGAATGGACCAGCTGGTCACCATGTTCCGTAAAA
TGTGGAGAAGGTGAAACGTCTCGTACTAGAAATTTGATAAAAAACTTGAA
AAATGAATTGTGTATTCAATTGCCAAGAAAGGAGCAAAAAAATTGTGCCG
GTGCTCGATTGGAATGTGATCTCTCAAAGAAATGTAGTCTATTACCTTGG
AGCTCATGGAGTCCGTGTTCTGCATCTTGTACAACTGAAGGGAAAATGAT
CAGAATTAGAAAATTTGCGAGGTCAAAAGAAAAGGACGAATGCATGAAAA
ACGTCAAACCAGAAATTATTCTTCAACAAGTGAAAACTTGTAAATTGGAT
AAAACGGACTTCCGATGTGATCCGATATCAATTTGCAGCGCCGGTAAATT
GGCACCTTGCATCAATGGTAAACCCAAGACGAGATTTTTCTACCACATCA
AAACTGGAAAATGCGAACCGTTTAAATACTATGATTGCAAAAAAGGAAAT
CTGAACAATTTCCCAACTATAGATTCATGTGAAAATGTTTGCTCTAAAGT
TATTCAGGAATTACCAAAAATAAGACGATCTAATTTAGCCTTGCTTCAAG
CAAGAACATCTTATTCAGCTGAAGAGAGTCTTTCGCAAAAAGCCAAAAAC
ATTCCGGAATTCTGCTTTCATGAAGTGGATTCCAGTAAGACCTGCATGAA
ATCCAAACCAAAGACAATCTGGTATTATAGTCATCGAAATCGAAAATGCC
AATCACTGGTGGATTATGATTGTAAAGGAACTTTAAATAAGTTTTCGACT
TTCGACGATTGCATGAAAACCTGCCGACCTGATTCACAACTCGAATCATT
GAAACTTGATAAAGTAGATTGTCAGGTCTCTGAATGGAGTTTATGGAGGC
CATGTTCAAAGTCATGCGGTTGGGGAACTCAATACAAGAAAAGAGTCATT
CAAAAGGATTCATTGAATGGGGGCTTACCATGTCCGGTGCTATATGAATC
TCGAAAATGCTTTTCCAAACCTTGTTAATCTGTCAATATTTATTTAAAAA
TTGTTTTTTGTGAATTATAATTTCTATTTCTTAATCTATTTGAAAATGTA
ATAAATATTACTTTGCGTATTTGATTTAGTTTAAAGTTTTCTCATTGGTC
AATCCGCCGTTGCTAACCAATGAGATCGGCTACTACATCAATTGCGATAA
TTGACAGTGGTGAGCAAACCTTTAAG

protein sequence of SMED30032088-orf-1

>SMED30032088-orf-1 ID=SMED30032088-orf-1|Name=SMED30032088-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=526bp
LPENRLNVKSLFTSGWLNGEEQLNEERSGFVSVNRTHNLFSMISMMGPSP
DWCTGVSGIDLCMDGCKWKSNLTIPLYPIDAGIQTGETYKPNNVTRLDEP
DTIREINKIWMKSNPFTPDTPVAEITLTRVEPQKDTQCVKTPVKGVNEFQ
NAQKESRSNTLGRNGAVEKYNVLDDPQLAQMAKAFCGFSEWTSWSPCSVK
CGEGETSRTRNLIKNLKNELCIQLPRKEQKNCAGARLECDLSKKCSLLPW
SSWSPCSASCTTEGKMIRIRKFARSKEKDECMKNVKPEIILQQVKTCKLD
KTDFRCDPISICSAGKLAPCINGKPKTRFFYHIKTGKCEPFKYYDCKKGN
LNNFPTIDSCENVCSKVIQELPKIRRSNLALLQARTSYSAEESLSQKAKN
IPEFCFHEVDSSKTCMKSKPKTIWYYSHRNRKCQSLVDYDCKGTLNKFST
FDDCMKTCRPDSQLESLKLDKVDCQVSEWSLWRPCSKSCGWGTQYKKRVI
QKDSLNGGLPCPVLYESRKCFSKPC*

Aliases

The feature 'Spondin-1' has the following synonyms


Synonym
spondin1-like

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000211	primitive ectoderm cell
PLANA:0004517	blastomere
PLANA:0000029	primitive ectoderm

Vocabulary: **INTERPRO**
Term	Definition
IPR038678	Spondin_N_sf
IPR036383	TSP1_rpt_sf
IPR036880	Kunitz_BPTI_sf
IPR000884	TSP1_rpt
IPR002223	Kunitz_BPTI
IPR009465	Spondin_N

Vocabulary: **molecular function**
Term	Definition
GO:0004867	serine-type endopeptidase inhibitor activity

Vocabulary: **biological process**
Term	Definition
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **Schmidtea mediterranea Developmental Stages**
Term	Definition
PLANA:0000003	Stage 3
PLANA:0000002	Stage 2
PLANA:0000004	Stage 4

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 403..459 e-value: 1.1E-6 score: 38.2 coord: 310..365 e-value: 6.7E-8 score: 42.2
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 320..364 e-value: 3.5E-10 score: 39.9 coord: 405..459 e-value: 1.5E-7 score: 31.5
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 313..364 score: 11.742
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 405..458 score: 10.517
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 327..364 e-value: 1.71104E-9 score: 51.4818
IPR000884	Thrombospondin type-1 (TSP1) repeat	SMART	SM00209	TSP1_2	coord: 476..524 e-value: 6.2E-6 score: 35.7 coord: 247..303 e-value: 0.015 score: 24.5 coord: 188..240 e-value: 3.6E-8 score: 43.1
IPR000884	Thrombospondin type-1 (TSP1) repeat	PFAM	PF00090	TSP_1	coord: 477..525 e-value: 1.9E-7 score: 31.2 coord: 249..300 e-value: 1.1E-6 score: 28.7 coord: 189..221 e-value: 8.9E-6 score: 25.8
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 185..240 score: 10.101
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 473..524 score: 9.869
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 244..301 score: 8.365
IPR009465	Spondin, N-terminal	PFAM	PF06468	Spond_N	coord: 21..109 e-value: 3.1E-23 score: 82.9
IPR009465	Spondin, N-terminal	PROSITE	PS51020	SPONDIN	coord: 1..118 score: 26.209
IPR038678	Spondin, N-terminal domain superfamily	GENE3D	G3DSA:2.60.40.2130		coord: 3..116 e-value: 2.0E-25 score: 91.8
IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily	GENE3D	G3DSA:2.20.100.10		coord: 183..239 e-value: 1.3E-9 score: 40.1 coord: 242..302 e-value: 3.5E-7 score: 32.3
IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily	GENE3D	G3DSA:2.20.100.10		coord: 471..520 e-value: 4.2E-14 score: 54.6
IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily	SUPERFAMILY	SSF82895	TSP-1 type 1 repeat	coord: 244..283
IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily	SUPERFAMILY	SSF82895	TSP-1 type 1 repeat	coord: 186..232
IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily	SUPERFAMILY	SSF82895	TSP-1 type 1 repeat	coord: 472..521
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 383..460 e-value: 7.9E-10 score: 40.5
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 307..368 e-value: 2.4E-11 score: 45.4
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 321..368
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 400..460
None	No IPR available	PANTHER	PTHR11311:SF23	FAT-SPONDIN	coord: 23..95 coord: 402..525
None	No IPR available	PANTHER	PTHR11311	F-SPONDIN	coord: 182..373
None	No IPR available	PANTHER	PTHR11311	F-SPONDIN	coord: 23..95 coord: 402..525
None	No IPR available	PANTHER	PTHR11311:SF23	FAT-SPONDIN	coord: 182..373

Main menu

Spondin-1

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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