Nucleotidyltransferase FAM46C

Overview
NameNucleotidyltransferase FAM46C
Smed IDSMED30032022
Length (bp)1781
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Nucleotidyltransferase FAM46C (SMED30032022) t-SNE clustered cells

Violin plots show distribution of expression levels for Nucleotidyltransferase FAM46C (SMED30032022) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nucleotidyltransferase FAM46C (SMED30032022) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Nucleotidyltransferase FAM46C (SMED30032022) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30032022

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30032022SMESG000003588.1 dd_Smed_v4_5263_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30032022SMESG000003588.1 dd_Smed_v4_5263_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30032022SMESG000003588.1 dd_Smed_v4_5263_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345])

HSP 1 Score: 226.868 bits (577), Expect = 2.830e-67
Identity = 143/392 (36.48%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +L + +  + D+RLNG  A+ VL       Y D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:   64 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADL----RGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 437
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345])

HSP 1 Score: 226.483 bits (576), Expect = 6.478e-67
Identity = 143/392 (36.48%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +L + +  + D+RLNG  A+ VL       Y D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:   83 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADL----RGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 456
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345])

HSP 1 Score: 226.868 bits (577), Expect = 1.889e-66
Identity = 143/392 (36.48%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +L + +  + D+RLNG  A+ VL       Y D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:  145 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADL----RGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 518
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Match: TENT5C (terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712])

HSP 1 Score: 218.779 bits (556), Expect = 8.575e-65
Identity = 132/348 (37.93%), Postives = 198/348 (56.90%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMD-NDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTN----KNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            SVL + QV RL  +L E   I G    P + +T+KD +  V+ +LE+    + D+RLNG  A  VL         D+D++      H+    +  F      VL  + + L   +     +  + K +Y+ KLV++    + D WSL+ L  S + G   + ++LKF   ++RQFEFS+DSFQI+LDSLL FY+          C+N    ++F+PTV   S + +  +A +HL NR I T  PE IRGGGLLKY  LLV++F   D  ++  LERYMCSRFFID+ D+  Q + + +YLQNHF  ++     +L  L+RV+++S++CLM  ER+QTL LI  +A+ +
Sbjct:   15 SVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIF-----HVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKV--CTDTDRWSLISL--SNKNG---KNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYD----------CSNNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRV 340
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Match: TENT5B (terminal nucleotidyltransferase 5B [Source:HGNC Symbol;Acc:HGNC:28273])

HSP 1 Score: 219.164 bits (557), Expect = 1.742e-64
Identity = 130/333 (39.04%), Postives = 189/333 (56.76%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ---PFLETLKRVISDSSICLMNQERQQT 1351
            S L + QV+RLDA+L+E   I G    P + V  +  +  V+  LE+    +  +RL+G  A+ VL P     Y D+D++  +D       +  F  T   VL  + D L   +        + K +Y+ KLV++    + D WSL+ L  S + G   + ++LKF   ++RQFEFSIDSFQI+LDSLL+F +       S    ++ F+PTV+  S + + ++AL HL +R I T  PE IRGGGLLKYC LLV+ F     + V  L+RYMCSRFFID+ DL  Q + +  YL+ HF   D+      L TL RV+++S++CLMN ER+QT
Sbjct:   50 SGLSWPQVKRLDALLSEPIPIHGRGNFPTLSVQPRQIVQVVRSTLEEQGLHVHSVRLHGSAASHVLHPESGLGYKDLDLVFRVD----LRSEASFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKV--CTDSDRWSLISL--SNKSG---KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQC------SSTPMSEAFHPTVTGESLYGDFTEALEHLRHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRTLERYLEAHFGGADAARRYACLVTLHRVVNESTVCLMNHERRQT 365
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Match: pqn-44 (Prion-like-(Q/N-rich)-domain-bearing protein [Source:UniProtKB/TrEMBL;Acc:Q86NJ5])

HSP 1 Score: 192.2 bits (487), Expect = 1.060e-54
Identity = 132/396 (33.33%), Postives = 198/396 (50.00%), Query Frame = 2 
Query:  353 SKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIK-AVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLD----------------DSQP-------------------FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            S+  +L   Q++RL A+L E   I G    P I   + + I  ++  +   Q    D+RLNGG A+ V      + Y D+D++  I +D    +N +    D I+ +V   I +L+   +      F++ K  YI K++++  S + D WSL  L  +  +G   R I+LKF ++M+RQFEFS+DSFQI LD LL   +          C  K     +++ S + ++  A+ HL  R I T +PE IRGGGLLKYC L+++ +         KLERYMCSRFFID+ DL SQ   + +YL +HF                   DS+                    FL  L RVI +S++CLM  ER  +L +ID++A ++S      PN  SG+
Sbjct:   45 SRTMILAKGQMKRLRAVLEERVEIHGRGNFPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD-FSYADLDLIFPIQIDEESDENVEKQIFDAIRDSVFMTIRELMPDNIGKEKFDFETLKDVYIRKMIKV--STDNDKWSLFSL--NNEYG---RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNELDE---------CEQKK----ITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFPDLISQENKLRNYLDSHFGTSFNGATYDQWSSSGSDTDSEASTSQATTSSLLVTGQAKYDFLMLLYRVIDESTVCLMAHERNMSLNMIDRVAFQLSMQCYTPPNFSSGS 419
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Match: pqn-44 (Prion-like-(Q/N-rich)-domain-bearing protein [Source:UniProtKB/TrEMBL;Acc:Q86NJ5])

HSP 1 Score: 192.2 bits (487), Expect = 1.060e-54
Identity = 132/396 (33.33%), Postives = 198/396 (50.00%), Query Frame = 2 
Query:  353 SKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIK-AVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLD----------------DSQP-------------------FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            S+  +L   Q++RL A+L E   I G    P I   + + I  ++  +   Q    D+RLNGG A+ V      + Y D+D++  I +D    +N +    D I+ +V   I +L+   +      F++ K  YI K++++  S + D WSL  L  +  +G   R I+LKF ++M+RQFEFS+DSFQI LD LL   +          C  K     +++ S + ++  A+ HL  R I T +PE IRGGGLLKYC L+++ +         KLERYMCSRFFID+ DL SQ   + +YL +HF                   DS+                    FL  L RVI +S++CLM  ER  +L +ID++A ++S      PN  SG+
Sbjct:   45 SRTMILAKGQMKRLRAVLEERVEIHGRGNFPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD-FSYADLDLIFPIQIDEESDENVEKQIFDAIRDSVFMTIRELMPDNIGKEKFDFETLKDVYIRKMIKV--STDNDKWSLFSL--NNEYG---RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNELDE---------CEQKK----ITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFPDLISQENKLRNYLDSHFGTSFNGATYDQWSSSGSDTDSEASTSQATTSSLLVTGQAKYDFLMLLYRVIDESTVCLMAHERNMSLNMIDRVAFQLSMQCYTPPNFSSGS 419
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Match: pqn-44 (Prion-like-(Q/N-rich)-domain-bearing protein [Source:UniProtKB/TrEMBL;Acc:Q86NJ5])

HSP 1 Score: 192.2 bits (487), Expect = 1.583e-54
Identity = 132/396 (33.33%), Postives = 198/396 (50.00%), Query Frame = 2 
Query:  353 SKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIK-AVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLD----------------DSQP-------------------FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            S+  +L   Q++RL A+L E   I G    P I   + + I  ++  +   Q    D+RLNGG A+ V      + Y D+D++  I +D    +N +    D I+ +V   I +L+   +      F++ K  YI K++++  S + D WSL  L  +  +G   R I+LKF ++M+RQFEFS+DSFQI LD LL   +          C  K     +++ S + ++  A+ HL  R I T +PE IRGGGLLKYC L+++ +         KLERYMCSRFFID+ DL SQ   + +YL +HF                   DS+                    FL  L RVI +S++CLM  ER  +L +ID++A ++S      PN  SG+
Sbjct:   61 SRTMILAKGQMKRLRAVLEERVEIHGRGNFPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD-FSYADLDLIFPIQIDEESDENVEKQIFDAIRDSVFMTIRELMPDNIGKEKFDFETLKDVYIRKMIKV--STDNDKWSLFSL--NNEYG---RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNELDE---------CEQKK----ITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFPDLISQENKLRNYLDSHFGTSFNGATYDQWSSSGSDTDSEASTSQATTSSLLVTGQAKYDFLMLLYRVIDESTVCLMAHERNMSLNMIDRVAFQLSMQCYTPPNFSSGS 435
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Match: pqn-44 (Prion-like-(Q/N-rich)-domain-bearing protein [Source:UniProtKB/TrEMBL;Acc:Q86NJ5])

HSP 1 Score: 192.2 bits (487), Expect = 2.070e-54
Identity = 132/396 (33.33%), Postives = 197/396 (49.75%), Query Frame = 2 
Query:  353 SKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIK-AVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLD----------------DSQP-------------------FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            S+  +L   Q++RL A+L E   I G    P I   + + I  ++  +   Q    D+RLNGG A+ V      + Y D+D++  I +D    +N +    D I+ +V   I +L+   +      F++ K  YI K++++   N  D WSL  L  +  +G   R I+LKF ++M+RQFEFS+DSFQI LD LL   +          C  K     +++ S + ++  A+ HL  R I T +PE IRGGGLLKYC L+++ +         KLERYMCSRFFID+ DL SQ   + +YL +HF                   DS+                    FL  L RVI +S++CLM  ER  +L +ID++A ++S      PN  SG+
Sbjct:   69 SRTMILAKGQMKRLRAVLEERVEIHGRGNFPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD-FSYADLDLIFPIQIDEESDENVEKQIFDAIRDSVFMTIRELMPDNIGKEKFDFETLKDVYIRKMIKVSTDN--DKWSLFSL--NNEYG---RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNELDE---------CEQKK----ITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFPDLISQENKLRNYLDSHFGTSFNGATYDQWSSSGSDTDSEASTSQATTSSLLVTGQAKYDFLMLLYRVIDESTVCLMAHERNMSLNMIDRVAFQLSMQCYTPPNFSSGS 443
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Match: pqn-44 (Prion-like-(Q/N-rich)-domain-bearing protein [Source:UniProtKB/TrEMBL;Acc:Q86NJ5])

HSP 1 Score: 192.2 bits (487), Expect = 2.260e-54
Identity = 132/396 (33.33%), Postives = 197/396 (49.75%), Query Frame = 2 
Query:  353 SKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIK-AVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLD----------------DSQP-------------------FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            S+  +L   Q++RL A+L E   I G    P I   + + I  ++  +   Q    D+RLNGG A+ V      + Y D+D++  I +D    +N +    D I+ +V   I +L+   +      F++ K  YI K++++   N  D WSL  L  +  +G   R I+LKF ++M+RQFEFS+DSFQI LD LL   +          C  K     +++ S + ++  A+ HL  R I T +PE IRGGGLLKYC L+++ +         KLERYMCSRFFID+ DL SQ   + +YL +HF                   DS+                    FL  L RVI +S++CLM  ER  +L +ID++A ++S      PN  SG+
Sbjct:   74 SRTMILAKGQMKRLRAVLEERVEIHGRGNFPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD-FSYADLDLIFPIQIDEESDENVEKQIFDAIRDSVFMTIRELMPDNIGKEKFDFETLKDVYIRKMIKVSTDN--DKWSLFSL--NNEYG---RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNELDE---------CEQKK----ITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFPDLISQENKLRNYLDSHFGTSFNGATYDQWSSSGSDTDSEASTSQATTSSLLVTGQAKYDFLMLLYRVIDESTVCLMAHERNMSLNMIDRVAFQLSMQCYTPPNFSSGS 448
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Match: CG46385 (gene:FBgn0286778 transcript:FBtr0474227)

HSP 1 Score: 243.817 bits (621), Expect = 5.052e-73
Identity = 142/351 (40.46%), Postives = 210/351 (59.83%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE------DYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP----FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QV +L  +++E   I G    P + V +KD +  V+ KLE           + DIRLNGG A+ VL   +   YND+D++  ++ S        F+    AVL  + DL+   +        S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL  + I T QPE IRGGGLLKYC LLV+N+   D   +  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +P    +L  L+ V+  S++CLM  ER+Q+L+LI  +A ++
Sbjct:   50 AVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLAS-EDQPYNDLDLIFAIELS----SPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQV 385
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Match: CG46385 (gene:FBgn0286778 transcript:FBtr0474226)

HSP 1 Score: 243.817 bits (621), Expect = 5.052e-73
Identity = 142/351 (40.46%), Postives = 210/351 (59.83%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE------DYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP----FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QV +L  +++E   I G    P + V +KD +  V+ KLE           + DIRLNGG A+ VL   +   YND+D++  ++ S        F+    AVL  + DL+   +        S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL  + I T QPE IRGGGLLKYC LLV+N+   D   +  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +P    +L  L+ V+  S++CLM  ER+Q+L+LI  +A ++
Sbjct:   50 AVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLAS-EDQPYNDLDLIFAIELS----SPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQV 385
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Match: CG46385 (gene:FBgn0286778 transcript:FBtr0474225)

HSP 1 Score: 243.817 bits (621), Expect = 9.340e-73
Identity = 142/351 (40.46%), Postives = 210/351 (59.83%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE------DYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP----FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QV +L  +++E   I G    P + V +KD +  V+ KLE           + DIRLNGG A+ VL   +   YND+D++  ++ S        F+    AVL  + DL+   +        S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL  + I T QPE IRGGGLLKYC LLV+N+   D   +  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +P    +L  L+ V+  S++CLM  ER+Q+L+LI  +A ++
Sbjct:   81 AVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLAS-EDQPYNDLDLIFAIELS----SPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQV 416
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Match: CG46385 (gene:FBgn0286778 transcript:FBtr0474229)

HSP 1 Score: 244.973 bits (624), Expect = 3.170e-71
Identity = 142/351 (40.46%), Postives = 210/351 (59.83%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE------DYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP----FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QV +L  +++E   I G    P + V +KD +  V+ KLE           + DIRLNGG A+ VL   +   YND+D++  ++ S        F+    AVL  + DL+   +        S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL  + I T QPE IRGGGLLKYC LLV+N+   D   +  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +P    +L  L+ V+  S++CLM  ER+Q+L+LI  +A ++
Sbjct:   81 AVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLAS-EDQPYNDLDLIFAIELS----SPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQV 416
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Match: CG46385 (gene:FBgn0286778 transcript:FBtr0474224)

HSP 1 Score: 244.973 bits (624), Expect = 1.099e-70
Identity = 142/351 (40.46%), Postives = 210/351 (59.83%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE------DYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP----FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QV +L  +++E   I G    P + V +KD +  V+ KLE           + DIRLNGG A+ VL   +   YND+D++  ++ S        F+    AVL  + DL+   +        S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL  + I T QPE IRGGGLLKYC LLV+N+   D   +  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +P    +L  L+ V+  S++CLM  ER+Q+L+LI  +A ++
Sbjct:  398 AVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGVLVKDIRLNGGAASHVLAS-EDQPYNDLDLIFAIELS----SPRVFDRVKVAVLNTLLDLMPEGVCKRRIYTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYKAVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTVCLMGHERRQSLHLIQSLAAQV 733
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Match: TENT5A (terminal nucleotidyltransferase 5Aa [Source:NCBI gene;Acc:100330676])

HSP 1 Score: 239.195 bits (609), Expect = 1.145e-72
Identity = 151/402 (37.56%), Postives = 224/402 (55.72%), Query Frame = 2 
Query:  341 SDSESKN-SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            + +ES N SVL + QV+RLD IL ET  I G    P + +  +  + AV+ ++ +    + D+RLNG  A+ VL       Y D+D++  + L G      +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +     R + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE      +      K F+PT+   S + + + AL+HL N+ I T  PE IRGGGLLKYC LLV+ F     S++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC  +SYST
Sbjct:    6 AGAESSNFSVLSWEQVQRLDLILTETIPIHGRGNFPTLQMKPRQIVTAVRRRMREKSIHVRDVRLNGSAASHVLHGDSGLGYKDLDLIFRVELKG------ETEFQIVKNIVLDCLLDFLPDGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----RGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMA------KTFHPTIIGESVYGDFAAALDHLRNKIICTRNPEEIRGGGLLKYCHLLVRGFRAASESEMKSLQRYMCSRFFIDFSDISEQQRKLESYLQNHFVGLEDRKYDYLTTLHSVVNESTVCLMGHERRQTLGLIAMLAVRVLAEQNVIPNVANVTCYYQPAPYVADGNFSNYYIAQVQPVFTCHQQSYST 388
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Match: tent5ba (terminal nucleotidyltransferase 5ba [Source:ZFIN;Acc:ZDB-GENE-061110-129])

HSP 1 Score: 232.261 bits (591), Expect = 4.476e-70
Identity = 137/351 (39.03%), Postives = 204/351 (58.12%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPF--LETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPN 1411
            VL + QV+RLD+IL ET  + G    P + V  +  +  V+ +LE+    + D+RLNG  A+ VL       Y D+D++  +  S    DD  F      VL+ + D L   +     +  + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQIVLDSLL+F     R S + +  ++ F+PTV   S + N  +AL HL N+ I T  PE IRGGGLLKYC LLV+ F     S++  L+RYMCSRFFID+ D+  Q + + +YLQNHF   + + +  L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +A P 
Sbjct:   15 VLSWEQVQRLDSILGETVPVHGRGNFPTLSVQPRQIVQVVRARLEERGITVRDVRLNGSAASHVLHQDTGLGYKDLDLIFGVSLS----DDQAFRVVKDVVLDSLLDFLPEGVSKERISALTLKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSLRRQFEFSVDSFQIVLDSLLLF----DRCSETPM--SECFHPTVLGESMYGNFEEALGHLCNKAIATRNPEEIRGGGLLKYCHLLVRGFRPTSESEMKSLQRYMCSRFFIDFPDIGEQQRKLEAYLQNHFAGMEHKRYDCLVTLYHVVNESTVCLMGHERRQTLNLISMLALRVLAEQNAIPT 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Match: tent5ab (terminal nucleotidyltransferase 5Ab [Source:ZFIN;Acc:ZDB-GENE-071004-35])

HSP 1 Score: 229.18 bits (583), Expect = 6.945e-69
Identity = 132/356 (37.08%), Postives = 205/356 (57.58%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            VL + QV+RLDAIL E+  I G    P + +  +D +  V+ ++E+ +  + ++RLNG  A+ VL       Y D+D++   D       ++ F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE      +      + F+P++   S + + S AL+HL  + I T  PE IRGGGLLKYC LLV+ F     +++  LERYMCSRFFID+ D+  Q + + SYLQNHF  L++ +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T
Sbjct:   10 VLNWEQVKRLDAILTESIPIHGKWNFPTLEMKPRDIVKVVRCRMEERKIHVREVRLNGSAASHVLHEDSGLGYKDLDLIFCADLK----GEVEFQTVKDIVLDSLLDFLPEGVNKEKITPVTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIRLDSLLLFYECSENPMA------ETFHPSIVGESVYGDFSVALDHLQRKLICTRNPEEIRGGGLLKYCHLLVRGFRAASEAEMKLLERYMCSRFFIDFSDVAEQRRKLESYLQNHFVGLENRKYEYLTTLHSVVNESTVCLMGHERRQTLSLITMLAVRVLAEQNVIPNVANVT 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Match: tent5ab (terminal nucleotidyltransferase 5Ab [Source:ZFIN;Acc:ZDB-GENE-071004-35])

HSP 1 Score: 229.18 bits (583), Expect = 6.945e-69
Identity = 132/356 (37.08%), Postives = 205/356 (57.58%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            VL + QV+RLDAIL E+  I G    P + +  +D +  V+ ++E+ +  + ++RLNG  A+ VL       Y D+D++   D       ++ F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE      +      + F+P++   S + + S AL+HL  + I T  PE IRGGGLLKYC LLV+ F     +++  LERYMCSRFFID+ D+  Q + + SYLQNHF  L++ +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T
Sbjct:   10 VLNWEQVKRLDAILTESIPIHGKWNFPTLEMKPRDIVKVVRCRMEERKIHVREVRLNGSAASHVLHEDSGLGYKDLDLIFCADLK----GEVEFQTVKDIVLDSLLDFLPEGVNKEKITPVTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIRLDSLLLFYECSENPMA------ETFHPSIVGESVYGDFSVALDHLQRKLICTRNPEEIRGGGLLKYCHLLVRGFRAASEAEMKLLERYMCSRFFIDFSDVAEQRRKLESYLQNHFVGLENRKYEYLTTLHSVVNESTVCLMGHERRQTLSLITMLAVRVLAEQNVIPNVANVT 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Match: tent5bb (terminal nucleotidyltransferase 5Bb [Source:ZFIN;Acc:ZDB-GENE-060503-431])

HSP 1 Score: 224.942 bits (572), Expect = 3.039e-67
Identity = 133/358 (37.15%), Postives = 204/358 (56.98%), Query Frame = 2 
Query:  341 SDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPF--LETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHP 1408
            S+   +  VL + QV+RLD+IL E   I G    P + V  +  +  V+ +LE+    + D++LNG  A+ VL       Y D+D++  L  +    DD  F      VL+ + + L   +        + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+F     R S + +  +++F+PTV   S + +  +AL HL  + I T  PE IRGGGLLKYC LLV+ F     +++  L+RYMCSRFFID+ D+  Q + + +YLQNHF   + + +  L TL RV+ +S++CLM  ER+QTL LI  +A+ + +  +A P
Sbjct:    7 SEQNRRCCVLSWEQVQRLDSILGECVPIHGRGNFPTLSVQPRHIVQVVRARLEERGVKVRDVKLNGSAASYVLHQDTGLGYKDLDLIFGLSLT----DDKTFRLVKDVVLDCLLEFLPAGVSRDRITALTLKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSLRRQFEFSVDSFQIGLDSLLLF----DRCSETPM--SESFHPTVLGESMYGDFEEALGHLHAKIIATHSPEEIRGGGLLKYCHLLVRGFRPASEAQMKTLQRYMCSRFFIDFSDINEQQRKLEAYLQNHFNGMEHKRYDCLVTLHRVVDESTVCLMGHERRQTLALISSLALRVLAEQNAIP 347
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Xenopus
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:NCBI gene;Acc:100490270])

HSP 1 Score: 235.343 bits (599), Expect = 6.330e-71
Identity = 144/402 (35.82%), Postives = 219/402 (54.48%), Query Frame = 2 
Query:  332 CRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            C  S   +  +VL + QV+RLDAIL ET  I G    P + +     +  V+ +LE+    + D+RLNG  A+ +L       Y D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE  +   +      + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F     +++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+  +YST
Sbjct:   13 CTGSCDSANCNVLSWEQVQRLDAILTETIPIHGRGNFPTLEMKPSQIVKVVRSRLEEKGIRVRDVRLNGSAASHILHEDSGLGYKDLDLIFCTDL----RGEAEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----HGKNVELKFMDSLRRQFEFSVDSFQIKLDSLLLFYECSQNPMT------ETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRAASETEMKSLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLSLITMLAIRVLAEQNIIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQHTYST 397
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Xenopus
Match: tent5b (terminal nucleotidyltransferase 5B [Source:NCBI gene;Acc:549960])

HSP 1 Score: 228.794 bits (582), Expect = 1.457e-68
Identity = 134/366 (36.61%), Postives = 207/366 (56.56%), Query Frame = 2 
Query:  317 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF--QLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHP 1408
            M++   ++S +  + SVL + QVRRLDAIL E+  I G    P +    +D +  V+ +LE     + ++RLNG  A+ VL       Y D+D++ ++D    D     F     AVL  + D L   +        + K +Y+ KLV++      D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI+LDS+L+F +      S      ++F+PTV+  S + +  +A++HL NR I T  PE IRGGGLLKYC LLV+ F       +  ++RYMCSR+FID+ D++ Q + +  YLQ+HF    D    +L TL +V+++S++CLM  ER+QTL LI  +A+ + S  + HP
Sbjct:    1 MSSALSQASPTAPRFSVLSWPQVRRLDAILCESVPIHGRGNFPTLSCRPRDLVQVVRSRLEQKGILVHNVRLNGSAASYVLHHDSGLGYKDLDLIFMVDLKGPDA----FQVVKHAVLNCLLDFLPSGVNKEKITPMTLKEAYVQKLVKV--CTESDRWSLISLSNNS-----GKNMELKFVDSLRRQFEFSVDSFQIILDSMLMFSQCSENPMS------QSFHPTVTGESMYGDFEEAMDHLRNRIIATRNPEEIRGGGLLKYCNLLVRGFRPKSEVDMKTMQRYMCSRYFIDFPDIREQQRKLKCYLQDHFVGMEDKRYDYLMTLHQVVNESTVCLMGHERRQTLALIASLAVHVLSEQN-HP 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Xenopus
Match: ttk (TTK protein kinase [Source:Xenbase;Acc:XB-GENE-953775])

HSP 1 Score: 222.631 bits (566), Expect = 3.389e-66
Identity = 132/356 (37.08%), Postives = 205/356 (57.58%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            VL + QV RL++ L E   I G    P + +T+KD +  V+ +LE+    + D+RLNG  A+ VL       Y D+D++  +  S     +  F      V+ ++ + L   +     +  + K +Y+ KLV++    + D WSL+ L  S + G   R I+LKF   ++RQFEFS+DSFQI+LDSLL +++       S    +++F+PTV   S + +   A +HL N+ I T  PE IRGGGL+KY  LLV++F   D  ++  LERYMCSRFFID+ D+  Q + + SYLQNHF  ++     +L  L+RV+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T
Sbjct:   18 VLTWEQVSRLNSFLTEVVPIHGRGNFPTLKITLKDIVQKVRSRLEEAGIKVRDVRLNGSAASHVLVKDNGLGYKDLDLIFGVSLS----SEAEFQLVKDVVIGLLLNFLPEGVNKEKISPLTLKEAYVQKLVKV--FTDADRWSLISL--SNKDG---RNIELKFVTSIRRQFEFSVDSFQIILDSLLFYHDC------SENPMSEHFHPTVIGESMYGDFEAAFHHLRNKLISTKNPEEIRGGGLMKYSNLLVRDFKPADKEQIKSLERYMCSRFFIDFSDIFEQQRKLESYLQNHFMGEEKSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPNATNVT 356
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Xenopus
Match: TENT5D (terminal nucleotidyltransferase 5D [Source:HGNC Symbol;Acc:HGNC:28399])

HSP 1 Score: 205.682 bits (522), Expect = 9.672e-60
Identity = 132/377 (35.01%), Postives = 204/377 (54.11%), Query Frame = 2 
Query:  323 ATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKN-----FYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEF 1432
            +T CR S+       L + Q+  LD +L E   I G    P + V  KD I  V+ +L   +  + DIRLNG  A+ +L         D+DI+    G  +  +   F    + VL+ + D L   +        + K +Y+ K+V++  S + D WSL+ L  +       + ++LKF + ++RQFEFS+DSFQI+LDS+L           SV   +KN      +PTV   S + +  +A+ HL  + I T  PE IRGGGLLKY  LLV++F     +++  LERYMCSRFFID+ D+  Q + I SYL+NHF  ++     +L TL+ V+++S++CLM+ ER+QTL +I  +A+++    +  PN  + T F
Sbjct:    7 STYCRFSN-------LTWDQIIILDQVLTEVIPIHGRGNFPTMEVKPKDIIHVVREQLLKKKIIVKDIRLNGSTASHILIKQNGTSCKDLDIIF---GVELPGEQ-EFQTVKEIVLDSLLDFLPKCVNKEKITALTMKEAYVQKMVKV--STDHDRWSLISLSNNS-----GKNVELKFVNSLRRQFEFSVDSFQIILDSIL-----------SVYTDDKNELKQDSHPTVVAESMYGDFMEAMEHLRCKLIATRNPEEIRGGGLLKYSNLLVRDFKPASEAEIKSLERYMCSRFFIDFPDVTEQQRKIESYLRNHFIGEEKSKYDYLMTLRSVVNESTVCLMSHERRQTLNMITILALKVLGEQNIIPNTANVTCF 354
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Match: Tent5a (terminal nucleotidyltransferase 5A [Source:MGI Symbol;Acc:MGI:2670964])

HSP 1 Score: 229.18 bits (583), Expect = 2.154e-68
Identity = 144/392 (36.73%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +LE+    + D+RLNG  A+ VL       Y D+D++   D    +     F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:   50 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLEEKGIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEE----FQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASEEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 423
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Match: Tent5a (terminal nucleotidyltransferase 5A [Source:MGI Symbol;Acc:MGI:2670964])

HSP 1 Score: 228.794 bits (582), Expect = 4.691e-68
Identity = 144/392 (36.73%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +LE+    + D+RLNG  A+ VL       Y D+D++   D    +     F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:   69 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLEEKGIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEE----FQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASEEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 442
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Match: Tent5c (terminal nucleotidyltransferase 5C [Source:MGI Symbol;Acc:MGI:1921895])

HSP 1 Score: 221.861 bits (564), Expect = 3.776e-66
Identity = 137/359 (38.16%), Postives = 203/359 (56.55%), Query Frame = 2 
Query:  317 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMD-NDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            M      + DSES  SVL + QV RL  +L E   I G    P + +T+KD +  V+ +LE+    + D+RLNG  A  VL         D+D++      H+    +  F      VL  + + L   +     +  + K +Y+ KLV++    + D WSL+ L  S + G   R ++LKF   ++RQFEFS+DSFQI+LDSLL FY+       S    +++F+PTV   S + +  +A +HL NR I T  PE IRGGGLLKY  LLV++F   D  ++  LERYMCSRFFID+ D+  Q + + +YLQNHF  ++     +L  L+RV+++S++CLM  ER+QTL LI  +A+ +
Sbjct:    1 MAEEGSSTKDSESF-SVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRGRLEEAGINVQDVRLNGSAAGHVLVKDNGLGCKDLDLIF-----HVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKV--CTDTDRWSLISL--SNKNG---RNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDC------SGNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFSDEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRV 340
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Match: Tent5b (terminal nucleotidyltransferase 5B [Source:MGI Symbol;Acc:MGI:2140500])

HSP 1 Score: 215.698 bits (548), Expect = 2.709e-63
Identity = 131/344 (38.08%), Postives = 197/344 (57.27%), Query Frame = 2 
Query:  359 NSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ---PFLETLKRVISDSSICLMNQERQQTLYLIDQIAME 1381
             S L + QV+RLDA+L E   I G    P + V  +  +  V+  LE++   +  +RL+G  A+ VL P     Y D+D++  +D       ++ F  T   VL  + D L   +        + K +Y+ KLV++    + D WSL+ L  S + G   + ++LKF   ++RQFEFSIDSFQI+LDSLL+F +       S    ++ F+PTV+  S + + ++AL HL +R I T  PE IRGGGLLKYC LLV+ F     + V  L+RYMCSRFFID+ DL  Q + +  YL+ HF   ++      L TL +V+++S++CLM+ ER+QTL LI  +A++
Sbjct:   49 QSRLSWPQVKRLDALLKEPIPIHGRGNFPTLSVQPQQIVQVVRSSLEEHGLRVHSVRLHGSAASHVLHPESGLGYKDLDLVFQMD----LRSEVSFQLTKAVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKV--CTDLDRWSLISL--SNKSG---KNVELKFVDSVRRQFEFSIDSFQIILDSLLLFGQC------SSTPMSEAFHPTVTGESLYGDFAEALEHLQHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVRALQRYMCSRFFIDFPDLVEQRRILERYLEAHFGGAEAARRYACLVTLHQVVNESTVCLMSHERRQTLDLIAMLALQ 375
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Match: Tent5d (terminal nucleotidyltransferase 5D [Source:MGI Symbol;Acc:MGI:2685223])

HSP 1 Score: 211.846 bits (538), Expect = 2.802e-62
Identity = 134/364 (36.81%), Postives = 197/364 (54.12%), Query Frame = 2 
Query:  347 SESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF--QLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEF 1432
            SE + S L +  +  LD +L+E   I G    P + V  KD I  VK +L      + D RLNG  A+ +L       Y D+DI+  +D       D  F+    AVL  + D L   ++      K+ K +Y+ K+V+I   NN D WSL+ L  +       + ++LKF + ++RQFEFS+DSFQI+LDS+L FY       +   C      P V   S + +  +A+ HL  + I T +PE IRGGGLLKY  LLV++F     +++  LERYMCSRFFID+ D+  Q K I SYL NHF  +  +   +L TL  V++ S++CLM  ER+QTL +I  +A+++    +  P+  + T F
Sbjct:    2 SEIRFSNLTWDHIVTLDRVLHEVIPIHGRGNFPTLEVKPKDIIHIVKDQLIKQGIVVKDTRLNGSTASYILASHNGISYKDLDIIFGVDIP----SDEEFHVVKDAVLSCLFDFLPKGVKKEKITLKTMKEAYVQKMVKI--CNNHDRWSLISLSNNN-----GKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESC------PVVVAESMYGDFQEAMIHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQTEIKTLERYMCSRFFIDFPDVAEQQKKIESYLHNHFIGEAKNKYDYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCF 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Match: sp|Q96IP4|TET5A_HUMAN (Terminal nucleotidyltransferase 5A OS=Homo sapiens OX=9606 GN=TENT5A PE=1 SV=2)

HSP 1 Score: 226.868 bits (577), Expect = 1.359e-66
Identity = 143/392 (36.48%), Postives = 216/392 (55.10%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            +VL + QV+RLD IL+ET  I G    P + +     +  V+ +L + +  + D+RLNG  A+ VL       Y D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + +  +A +HL N+ I T  PE IRGGGLLKYC LLV+ F  P   ++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  + TC+ ++YST
Sbjct:   64 NVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADL----RGEGEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFR-PASDEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYST 437
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Match: sp|Q29RH2|TET5B_BOVIN (Terminal nucleotidyltransferase 5B OS=Bos taurus OX=9913 GN=TENT5B PE=2 SV=1)

HSP 1 Score: 225.328 bits (573), Expect = 4.008e-66
Identity = 132/343 (38.48%), Postives = 198/343 (57.73%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ---PFLETLKRVISDSSICLMNQERQQTLYLIDQIAME 1381
            S L + QV+RLDA+L+E   I G    P + V  +  +  V+  LE+    +  +RL+G  A+ VL P     Y D+D++  +D       +  F  T + VL  + D L   +        + K +Y+ KLV++    + D WSL+ L  S + G   + ++LKF   ++RQFEFS+DSFQI+LDSLL+F +       S    ++ F+P+V+  S + + ++AL+HL +R I T  PE IRGGGLLKYC LLV+ F     + V  L+RYMCSRFFID+ DL  Q + +  YL+ HF   D+      L TL RV+++S++CLMN ER+QTL LI  +A++
Sbjct:   50 SGLSWPQVKRLDALLSEPIPIHGRGNFPTLSVQPRQIVQVVRSSLEEQGLRVHGVRLHGSAASHVLHPESGLGYKDLDLVFRVD----LRSEASFQLTKEVVLACLLDFLPAGVSRAKITPLTLKEAYVQKLVKV--CTDTDRWSLISL--SNKSG---KNVELKFVDSVRRQFEFSVDSFQILLDSLLLFSQC------SPTPMSEAFHPSVTGESLYGDFAEALDHLRHRVIATRSPEEIRGGGLLKYCHLLVRGFRPRPSTDVGALQRYMCSRFFIDFPDLVEQRRTLERYLEAHFSGADAARRYACLVTLHRVVNESTVCLMNHERRQTLDLITALALQ 375
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Match: sp|Q5XIV0|TET5C_RAT (Terminal nucleotidyltransferase 5C OS=Rattus norvegicus OX=10116 GN=Tent5c PE=2 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 6.406e-66
Identity = 139/359 (38.72%), Postives = 206/359 (57.38%), Query Frame = 2 
Query:  317 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMD-NDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            M      + DSES  SVL + QV RL  +L E   I G    P + +T+KD +  V+ +LE+    + D+RLNG  A  VL         D+D++      H+    +  F      VL  + + L   +     +  + K +Y+ KLV++    + D WSL+ L  S + G   R ++LKF   ++RQFEFS+DSFQI+LDSLL FY+     SS+ V  +++F+PTV   S + +  +A +HL NR I T  PE IRGGGLLKY  LLV++F   D  ++  LERYMCSRFFID+ D+  Q + + +YLQNHF  ++     +L  L+RV+++S++CLM  ER+QTL LI  +A+ +
Sbjct:    1 MADEGSSTKDSESF-SVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVQDVRLNGSAAGHVLVKDNGLGCKDLDLIF-----HVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKV--CTDTDRWSLISL--SNKNG---RNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDC----SSNPV--SEHFHPTVVGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFADEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRV 340
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Match: sp|Q7ZUP1|TET5C_DANRE (Terminal nucleotidyltransferase 5C OS=Danio rerio OX=7955 GN=tent5c PE=2 SV=1)

HSP 1 Score: 222.246 bits (565), Expect = 2.058e-65
Identity = 132/356 (37.08%), Postives = 200/356 (56.18%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            VL + QV RL+ +L E   + G    P + V +KD +  V+++LE     + D+RLNG  A+ VL     + Y D+D++  +D    +     F      VL  + D L   +        + K +Y+ KLV++    + D WSL+ L  +       R ++LKF   ++RQFEFS+DSFQI+LDS+L +Y+      S      ++F+PTV   S + +  +AL HL N+ I T +PE IRGGGLLKYC LLV+ F   D  +   LERYMCSRFFID+ D+  Q + + +YLQ+HF  ++     +L  L+RV+++S++CLM  ER+QTL LI   A  + +  +A P+  S T
Sbjct:   17 VLTWEQVSRLNDVLTEAVPVHGRGNFPTLEVRLKDIVQMVRNRLELRGIMVKDVRLNGSTASHVLVQDIGWSYKDLDVIFRVDLPREEE----FQLIKDVVLSTLLDFLPEGVNKEKITPMTLKEAYVQKLVKVYT--DQDRWSLISLSNNN-----GRNVELKFVDSIRRQFEFSVDSFQIILDSVLSYYDLSENPMS------QHFHPTVVGESMYGDFVEALGHLTNKTIATKRPEEIRGGGLLKYCNLLVREFKPTDPDEFKALERYMCSRFFIDFPDIVEQQRKLEAYLQSHFIGEERNKYNYLMILRRVVNESTVCLMGHERRQTLNLISLTAFRVLAEQNAIPDVSSVT 355
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Match: sp|Q5SSF7|TET5C_MOUSE (Terminal nucleotidyltransferase 5C OS=Mus musculus OX=10090 GN=Tent5c PE=1 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 2.641e-65
Identity = 137/359 (38.16%), Postives = 203/359 (56.55%), Query Frame = 2 
Query:  317 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMD-NDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            M      + DSES  SVL + QV RL  +L E   I G    P + +T+KD +  V+ +LE+    + D+RLNG  A  VL         D+D++      H+    +  F      VL  + + L   +     +  + K +Y+ KLV++    + D WSL+ L  S + G   R ++LKF   ++RQFEFS+DSFQI+LDSLL FY+       S    +++F+PTV   S + +  +A +HL NR I T  PE IRGGGLLKY  LLV++F   D  ++  LERYMCSRFFID+ D+  Q + + +YLQNHF  ++     +L  L+RV+++S++CLM  ER+QTL LI  +A+ +
Sbjct:    1 MAEEGSSTKDSESF-SVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRGRLEEAGINVQDVRLNGSAAGHVLVKDNGLGCKDLDLIF-----HVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKV--CTDTDRWSLISL--SNKNG---RNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDC------SGNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFSDEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRV 340
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Match: T1K5N9 (Uncharacterized protein OS=Tetranychus urticae OX=32264 GN=107360693 PE=4 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 1.555e-79
Identity = 150/345 (43.48%), Postives = 209/345 (60.58%), Query Frame = 2 
Query:  347 SESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ--PFLETLKRVISDSSICLMNQERQQTLYLIDQIA 1375
            S  + +VL Y QV RLD +++E   I G    P + + +KD +  V+ KLE+    + DIRLNGG A+ VL P  L  YND+D++ ++D S   N    F+    AVL+ + D L   +  T  +  S K +Y+HK+V++  +  GD WSL+ L  +     R R ++LKF   M+RQFEFS+DSFQI+LDSLL FYE         +  ++NFYPTV   S + +  +AL HL  + I T  PE IRGGGLLKYC LLV+N+      ++  LERYMCSRFFID+ DL  Q + + SY+ NHF  DD     +L TL  V+ +S++CLM  ER+QTLYLI ++A
Sbjct:    4 SSDRYAVLSYEQVTRLDTVMDEVVPIHGRGNFPTLEMKLKDLVSVVRGKLEEENVTLRDIRLNGGAASYVLCPNNL-TYNDLDLIFVVDLSTSRN----FDKVRSAVLDSLLDFLPEGVNKTRISSCSLKEAYVHKMVKV--NEGGDRWSLISLSNN-----RGRNVELKFVDSMRRQFEFSVDSFQIILDSLLSFYEV-----DPPMRMSENFYPTVVGESVYGDFREALFHLNKKLIATRNPEEIRGGGLLKYCNLLVRNYRPARPDEIKNLERYMCSRFFIDFSDLCQQRRKLESYIANHFVGDDQMKCEYLMTLFNVVDESTVCLMGHERRQTLYLIQELA 331
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Match: A0A087TQV3 (Protein FAM46C (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_24614 PE=4 SV=1)

HSP 1 Score: 261.922 bits (668), Expect = 8.394e-78
Identity = 153/367 (41.69%), Postives = 213/367 (58.04%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMV-DIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ--PFLETLKRVISDSSICLMNQERQQTLYLIDQIAM-------EISSLYDAHPNEGSGTEF 1432
            +VL Y QV +LDA++ E   I G    P + V +KD +  V+ KLE  Q   V DIRLNGG A+ VL P +   YND+D++  +D S+  N    F+    AVL+ + D L   +     +  S K +Y+HK+V++    NGD WSL+ L  +     R R I+LKF   M+RQFEFS+DSFQI+LDSLL+FY        S +  + NFYPTV   S + +  +AL HL  + I T  PE IRGGGLLKYC LLV+++      K+  LERYMCSRFFID+ D+  Q   + SYL NHF  ++     +L  L RV+ +S++CLM  ER+Q+L LI+++A        +   L+  HP+   G  F
Sbjct:   40 AVLSYEQVSKLDAVMEEVMPIHGRGNFPTLEVRLKDLVRVVRAKLESEQSVAVRDIRLNGGAASHVLAP-EASPYNDLDLIFAVDLSNQRN----FDKVKTAVLDSLLDFLPEGVVKKRISSCSLKEAYVHKMVKV---TNGDRWSLISLSNN-----RGRNIELKFVDTMRRQFEFSVDSFQIILDSLLLFY------GCSQMSMSDNFYPTVVAESVYGDFQEALYHLHKKLIATRNPEEIRGGGLLKYCNLLVRDYKPARPDKIKHLERYMCSRFFIDFGDINQQRAKLESYLANHFMGEEQNKYEYLLVLHRVVDESTVCLMGHERRQSLALIEELACRTYFLEHQAKDLFQPHPHIVFGGGF 387
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Match: A0A4Y2FPK5 (Nucleotidyltransferase FAM46C OS=Araneus ventricosus OX=182803 GN=Fam46c PE=4 SV=1)

HSP 1 Score: 262.307 bits (669), Expect = 8.925e-78
Identity = 153/367 (41.69%), Postives = 214/367 (58.31%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMV-DIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ--PFLETLKRVISDSSICLMNQERQQTLYLIDQIAM-------EISSLYDAHPNEGSGTEF 1432
            +VL Y QV +LDA++ E   I G    P + V +KD +  V+ KLE  Q   V DIRLNGG A+ VL P +   YND+D++  +D S+  N    F+    AVL+ + D L   +     +  S K +Y+HK+V++    NGD WSL+ L  +     R R I+LKF   M+RQFEFS+DSFQI+LDSLL+FY        S +  ++NFYPTV   S + +  +AL HL  + I T  PE IRGGGLLKYC LLV+++      K+  LERYMCSRFFID+ D+  Q   + SYL NHF  ++     +L  L RV+ +S++CLM  ER+Q+L LI+++A        +   L+  HP+   G  F
Sbjct:   55 AVLSYEQVSKLDAVMEEVMPIHGRGNFPTLEVRLKDLVRVVRGKLESEQSVQVRDIRLNGGAASHVLAP-EASTYNDLDLIFAVDLSNQRN----FDRIKTAVLDSLLDFLPEGVVKKRISTCSLKEAYVHKMVKV---TNGDRWSLISLSNN-----RGRNIELKFVDTMRRQFEFSVDSFQIILDSLLLFY------GCSQMAMSENFYPTVVAESVYGDFQEALYHLHKKLIATRNPEEIRGGGLLKYCNLLVRDYKPARPEKIKHLERYMCSRFFIDFGDINQQRAKLESYLANHFMGEEQNKYEYLLVLHRVVDESTVCLMGHERRQSLALIEELACRTYYFEHQAKDLFQPHPHIVFGGGF 402
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Match: A0A0K8TR87 (Uncharacterized protein OS=Tabanus bromius OX=304241 PE=2 SV=1)

HSP 1 Score: 263.462 bits (672), Expect = 3.707e-77
Identity = 152/351 (43.30%), Postives = 218/351 (62.11%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLE-DYQ-----FPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ----PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            +VL + QVR+L+ +++ET  I G    P + V +KD +  V+ KLE D Q       + DIRLNGG A+ VL   +   YND+D++  ++ S       +F+    AVL  + DLL   +     +  S K +Y+ K+V++ N+N+GD WSL+ LG S   G+++  ++LKF   M+RQFEFS+DSFQIVLDSLL+FY+       + +  ++NFYPTV   S + +  +AL HL N+ I T QPE IRGGGLLKYC LLV+N+   D  K+  LERYMCSRFFID+ D+ +Q   + +YL+NHF   D +     +L  L+ V+  S++CLMN ER QTL LI  +AM+I
Sbjct:   78 AVLSFEQVRKLNDVMDETVSIHGRGNFPTLEVKLKDLVTLVRRKLELDVQSGGAGMIVKDIRLNGGAASHVLAS-EAQPYNDLDLIFAVEFS----SGRHFDRVKTAVLNTLLDLLPEGVSRRRISPCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSP--GHKN--VELKFVDTMRRQFEFSVDSFQIVLDSLLLFYDC------AALPISENFYPTVVGESVYGDFQEALYHLQNKLISTRQPEEIRGGGLLKYCNLLVRNYQPVDPDKIKTLERYMCSRFFIDFPDITTQTVKLEAYLRNHFWGADEEHLQYQYLMHLREVVETSTVCLMNHERHQTLLLIQTLAMQI 413
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Match: A0A5B7HSN0 (Protein FAM46C OS=Portunus trituberculatus OX=210409 GN=fam46c PE=4 SV=1)

HSP 1 Score: 259.225 bits (661), Expect = 1.889e-76
Identity = 147/344 (42.73%), Postives = 202/344 (58.72%), Query Frame = 2 
Query:  362 SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ---PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            SVL Y QVR L+ +L+E   I G    P + + ++D +  V+ KLE     + DIR+NGG A+ +L       YND+D++  +D S   + D   N    AVLEV+ D L   +     +  S K  Y+HK+V++   N+ D WSL+ L   G      R ++LKF   MKRQFEFS+DSFQ+VLDSLL+FYE         +  ++NFYPTV   S + + S+AL HL  + I T  PE IRGGGLLKYC LLV+ +      ++  LERYMCSRFFID+ D+  Q   I +YL NHF   D      FL  + RV+ DS++CLM  ER+QTL LID++A ++
Sbjct:   18 SVLTYEQVRHLNEVLHEVVSIHGRGNFPTLEIRLRDLVSLVRAKLEAEAVQVRDIRINGGAASHILAATPDQAYNDLDLIFAVDLSSPRSYDRVKN----AVLEVLLDFLPAGVSKRRMSSCSMKEGYVHKMVKV---NDTDRWSLISLSNHG-----GRNVELKFVDTMKRQFEFSVDSFQVVLDSLLLFYECAE------MPISENFYPTVMGESVYGDFSEALYHLQKKLIATKNPEEIRGGGLLKYCSLLVKEYEPARPDEIKTLERYMCSRFFIDFPDVSQQQSKIEAYLWNHFVGPDEALRYDFLMVVHRVVDDSTVCLMGHERRQTLNLIDELACQV 343
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Match: tent5ab (protein FAM46A-like [Source:NCBI gene;Acc:103042328])

HSP 1 Score: 232.646 bits (592), Expect = 3.770e-70
Identity = 137/371 (36.93%), Postives = 206/371 (55.53%), Query Frame = 2 
Query:  320 TATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            T    R+ ++    SVL + QV+RLDA+L E+  I G    P + +  +D +  V+ +L +    + ++RLNG  A+ VL       Y D+D++   D       +  F    + VL  + D L   +        + K +Y+ K+V++ N  + D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+P++   S + +  +AL HL +R I T  PE IRGGGLLKYC LLV+ F     S + +LERYMCSRFFID+ D   Q + + SYLQNHF  L+D +  +L TL  V+S+S++CLM  ER+Q L LI  +A+ + +  +  PN  + T
Sbjct:    6 TTEGARAEEARGSLSVLSWEQVQRLDALLAESIPIHGRWNFPTLHMKPRDIVRVVRARLRERHIDVREVRLNGSAASHVLHEDSGLGYKDLDLIFRADL----KGEREFQTVKEIVLHSLLDFLPAGVNKEKITPLTLKEAYVQKMVKVYN--DSDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIRLDSLLLFYEC------SENPMAETFHPSIVGESVYGDFEEALEHLRHRLICTRNPEEIRGGGLLKYCHLLVRGFRAASPSHMKQLERYMCSRFFIDFPDASEQRRKLESYLQNHFVGLEDRKYEYLSTLHGVVSESTVCLMGHERRQALSLITMLAVRVLAEQNVIPNVANVT 359
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Match: tent5bb (protein FAM46A-like [Source:NCBI gene;Acc:103036989])

HSP 1 Score: 229.565 bits (584), Expect = 4.981e-69
Identity = 134/359 (37.33%), Postives = 206/359 (57.38%), Query Frame = 2 
Query:  338 SSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPF--LETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHP 1408
             S+   +  VL + QV+RLD+IL E+  I G    P + V  +  +  V+ +LE+    + D++LNG  A+ VL       Y D+D++  L  +    DD  F      VL+ + + L   +     +  + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+F         S    +++F+PTV   S + +  +AL HL ++ I T  PE IRGGGLLKYC LLV+ F     S++  L+RYMCSRFFID+ D+  QH+ + +YLQNHF   + + +  L TL+RV+ +S++CLM  ER+QTL LI  +A+ + +  +A P
Sbjct:    7 GSELSRRFCVLSWEQVQRLDSILGESVPIHGRGNFPTLSVQPRQIVQVVRARLEERGVAVRDVKLNGSAASHVLHQDTGLGYKDLDLIFGLSLT----DDKTFRLVKDVVLDSLLEFLPVGVSRERISALTLKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSLRRQFEFSVDSFQIGLDSLLLFDRC------SETPMSESFHPTVLGESMYGDFEEALGHLRSKTIATRSPEEIRGGGLLKYCHLLVRGFRPVSESQIKTLQRYMCSRFFIDFPDIGEQHRKLEAYLQNHFNGIEHKRYECLVTLRRVVDESTVCLMGHERRQTLALISALALRVLAEQNAIP 348
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Match: tent5c (terminal nucleotidyltransferase 5C [Source:NCBI gene;Acc:103030177])

HSP 1 Score: 227.639 bits (579), Expect = 1.975e-68
Identity = 135/356 (37.92%), Postives = 205/356 (57.58%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQP--FLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            VL + QV RL+ +L E   + G    P + V +KD +  V+++LE     + D+RLNG  A+ VL     + Y D+DI+  +D       +  F      VL  + D L   +        + K +Y+ KLV++      D WSL+ L  +       R ++LKF   ++RQFEFS+DSFQI+LDSLL +Y+    FS + +  +++F+PTV   S + + + AL+HL N+ I T +PE IRGGGLLKYC LLV++F   D  +   LERYMCSRFFID+ D+  Q + + +YLQ+HF  ++     +L  L+RV+++S++CLM  ER+QTL LI   A  + +  +A P+  S T
Sbjct:   15 VLTWDQVSRLNEVLTEAVPVHGRGNFPTLEVRLKDIVQMVRNRLEQRGIQVKDVRLNGSTASHVLVKDIGWCYKDLDIIFRVDLPQ----EAQFQLIKDVVLGTLLDFLPEGVNKEKITPMTLKEAYVQKLVKVYTEQ--DRWSLISLSNNN-----GRNVELKFVDSIRRQFEFSVDSFQIILDSLLSYYD----FSETPM--SQHFHPTVLGESVYGDFAVALDHLKNKMIATKRPEEIRGGGLLKYCNLLVRDFRPTDEEEFKALERYMCSRFFIDFPDIGEQQRKLEAYLQSHFVGEEKSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLTAFRVLAEQNAIPDASSVT 353
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345])

HSP 1 Score: 221.09 bits (562), Expect = 6.388e-66
Identity = 140/390 (35.90%), Postives = 218/390 (55.90%), Query Frame = 2 
Query:  368 LKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVT-------YADQVD-LSTCKYRSYST 1507
            L + QV+RLD++L E+  I G    P + +  +  + AV+ ++E+ +  + D+RLNG  A+ VL       Y D+D++   +       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +     R + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE      +      K F+PT+   S + + + AL HL N+ I T  PE IRGGGLLKYC LLV+ F     +++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T +      V        Y  QV  +  C++++YST
Sbjct:   16 LIWEQVQRLDSLLTESIPIHGRGNFPTLQMKPRQIVKAVRRRMEERELRVRDVRLNGSAASHVLHEQSGLGYKDLDLIFCAELK----GEAEFQMVKDIVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----RGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMA------KTFHPTIIGESVYGDFNVALEHLRNKVICTRNPEEIRGGGLLKYCHLLVRGFRAASETEMKSLQRYMCSRFFIDFSDINEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLGLIAMLAVRVLAEQNVIPNVANVTCYYQPAPYVADGNFSNYYIAQVQPVFACQHQTYST 388
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Match: tent5ba (protein FAM46A-like [Source:NCBI gene;Acc:103046783])

HSP 1 Score: 216.083 bits (549), Expect = 5.711e-64
Identity = 129/350 (36.86%), Postives = 196/350 (56.00%), Query Frame = 2 
Query:  341 SDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPF--LETLKRVISDSSICLMNQERQQTLYLIDQIAMEI 1384
            S+   +  VL + QV+RLD+I+ E   I G    P + V  +  +  V+ +LE     + D+RLNG  A+ VL       Y D+D++  +  S    DD  F      VL+ + D L   +        + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+F         S    +++F+PTV   S + +  +A +HL ++ I T  PE IRGGGLLKYC LLV+ F     +++  L+RYMCSRFFID+ D+  Q + + SYLQNHF   + + +  L  L  V+++S++CLM  ER+QTL LI  +A+ +
Sbjct:    7 SEQSRRLCVLSWEQVQRLDSIIGEPVPIHGRGNFPTLSVQPRQIVQVVRERLEQQGVTVRDVRLNGSAASHVLHQDTGLGYKDLDLIFGVSLS----DDQAFRLVKDVVLDSLLDFLPEGVSKERITALTLKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSLRRQFEFSVDSFQIGLDSLLLFDRC------SETPMSESFHPTVVGESVYGDFEEAHSHLRDKIISTRNPEEIRGGGLLKYCHLLVRGFQPRSEAEMKSLQRYMCSRFFIDFPDIGEQQRKLESYLQNHFAGMEHKRYDCLVRLYHVVNESTVCLMGHERRQTLNLISTLALRV 339
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Sea Lamprey
Match: tent5ab (terminal nucleotidyltransferase 5Ab [Source:ZFIN;Acc:ZDB-GENE-071004-35])

HSP 1 Score: 114.005 bits (284), Expect = 1.813e-29
Identity = 73/215 (33.95%), Postives = 114/215 (53.02%), Query Frame = 2 
Query:  455 VTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDIL--IILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRG 1093
            V  +D +  V+ +LE+    + D+RLNG  A+ VL       Y D+D++  + L G      +  F    + VL+ + D L   +       ++ K +Y+ K+V++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQIVLDSLL+FYE       S    ++ F+P+V   S + +  +AL HL  R I T  PE IRG
Sbjct:    2 VRPRDIVRIVRGRLEERGIAVRDVRLNGSAASHVLHHDSGLSYKDLDLIFGVGLTG------EAEFQLVKEVVLDCLLDFLPEGVSKEKIGPQTLKEAYVQKMVKV--CNDTDRWSLISLSNNS-----GKNVELKFVDSLRRQFEFSVDSFQIVLDSLLLFYEC------SEHAMSERFHPSVLGESMYGDFGEALEHLRGRLIATRNPEEIRG 197
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Nematostella
Match: EDO30295 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T168])

HSP 1 Score: 238.424 bits (607), Expect = 2.715e-73
Identity = 142/360 (39.44%), Postives = 203/360 (56.39%), Query Frame = 2 
Query:  350 ESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILD-GSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF--QLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGS 1420
            ESK+ VL Y QV RLD +LN+   + G    P + V +++ I  V   L+D    + DIRLNG  A+ +L       YNDID++  ++  SH      +       VL  + + L   +     +  + K +Y+ K+V++ N N  D WSL+ L  +       + I+LKF   M+RQFEFS+DSFQ+ LDSLL FY+       S V    NF+PTV   S + ++  AL HL N+ I T  PE IRGGGLLKYC LLV+N+   ++ ++  LERYMCSRFFID+ DL+SQ + + SYL NHF  + D    +L  L  ++++S++CLM  ER+QTL LI  +A      Y     +GS
Sbjct:    4 ESKSQVLTYEQVHRLDNVLNQVVQVHGRGNFPTLDVHLRELINVVSSGLKDENLRIRDIRLNGSTASYILSRDSNTAYNDIDLIFGVEIKSH-----THLQQIKSVVLSSLLNFLPNGVSKEKMSSCTLKEAYVQKMVKVSNDN--DRWSLISLSNND-----GKNIELKFVDTMRRQFEFSVDSFQVNLDSLLGFYKL------SCVPMKPNFFPTVVAESVYGDIKVALFHLDNQLIATRNPEEIRGGGLLKYCNLLVRNYRPENMDELRLLERYMCSRFFIDFGDLESQRQKLESYLANHFIGENDTKYDYLSILYTIVANSTVCLMGHERRQTLRLISTLARRYCGQYFTQEEDGS 345
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Match: tent5bb (putative nucleotidyltransferase FAM46A [Source:NCBI gene;Acc:101172962])

HSP 1 Score: 239.58 bits (610), Expect = 1.081e-72
Identity = 138/367 (37.60%), Postives = 209/367 (56.95%), Query Frame = 2 
Query:  314 MMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ--PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHP 1408
            ++T + C +     + SVL + QVRRLD+IL E+  I G    P + V  +  +  V  +LE+    + D+RLNG  A+ VL       Y D+D++  L  +    DD  F      VL+ + D L   +        + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   M+RQFEFS+DSFQI LDSLL+F         S    ++ F+PTV   S + +  +AL+HL ++ I T  PE IRGGGLLKYC LLV+ F     S++ +++RYMCSRFFID+ D+  Q + + +YLQNHF   + +   +L TL+RV+ +S++CLM  ER+QTL LI  +A+ + +  +A P
Sbjct:   12 LLTMSSCDAPAQSRRLSVLSWDQVRRLDSILGESVPIHGRGNFPTLSVQPRQIVQVVMARLEEEGVVVRDVRLNGSAASHVLHQDNGLGYKDLDLIFGLSLT----DDKTFRLIKDVVLDCLVDFLPEGVCRERITALALKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSMRRQFEFSVDSFQITLDSLLLFDRC------SETAMSETFHPTVQGESMYGDFQEALHHLRSKTIATRSPEEIRGGGLLKYCHLLVRGFHPSSESQMKQMQRYMCSRFFIDFPDINEQQRKLEAYLQNHFAGIEHKRYEYLVTLRRVVDESTVCLMGHERRQTLALISALAIRVMAEQNAIP 361
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Match: tent5ba (terminal nucleotidyltransferase 5B [Source:NCBI gene;Acc:101173494])

HSP 1 Score: 233.802 bits (595), Expect = 1.127e-70
Identity = 137/359 (38.16%), Postives = 211/359 (58.77%), Query Frame = 2 
Query:  341 SDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPF--LETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPN 1411
            SD   +  VL + QVRRLD+IL E+  I G    P + V  +  +  V+ +L++    + D+RLNG  A+ VL       Y D+D++    G  +  DD  F      VL+ + D L P +        + K +Y+ KLV++   N+ D WSL+ L  +       + ++LKF   ++RQFEFS+DSFQI LDSLL+F     R S + +  +++F+PTV   S + + S+AL+HL  R I T  PE IRGGGLLKYC LLV+ F+    + + +++RYMCSRFFID+ D+  Q + + +YLQNHF   + + +  L TL +V+++S++CLM  ER+QTL LI  +A+++ +  +A P 
Sbjct:    5 SDQSRRFCVLSWDQVRRLDSILAESVPIHGRGNFPTLSVQPRQIVQVVRARLQERGICVKDVRLNGSAASHVLHQGNGLGYKDLDLIF---GVSL-KDDQAFRLVKDVVLDCLLDFLPPGVSKERITALTLKEAYVQKLVKV--CNDTDRWSLISLSNNT-----GKNVELKFVDSLRRQFEFSVDSFQICLDSLLLF----DRCSETPM--SESFHPTVIGESVYGDFSEALDHLCRRTIATRSPEEIRGGGLLKYCHLLVRGFTPSSEADMKQMQRYMCSRFFIDFPDIGEQQRKLEAYLQNHFVGMEHKRYECLMTLHQVVNESTVCLMGHERRQTLSLISMLALKVLAEQNAIPT 346
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:NCBI gene;Acc:101158475])

HSP 1 Score: 231.106 bits (588), Expect = 1.749e-69
Identity = 133/353 (37.68%), Postives = 205/353 (58.07%), Query Frame = 2 
Query:  374 YSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            + QV+RLDAIL ET  I G    P + +  +  +  V+ ++E+ +  + D+RLNG  A+ +L       + D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +     R + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + ++S+AL+HL ++ I T  PE IRGGGLLKYC LLV+ F     S++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T
Sbjct:   29 WDQVQRLDAILTETIPIHGRGNFPTLQMQPRQIVKVVRSRMEEKRIHVRDVRLNGSAASHILHDDSGLGFKDLDLIFCADMK----GESEFQTVKDIVLDCLLDFLPDCVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----RGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIMGESVYGDISEALDHLRHKIICTRNPEEIRGGGLLKYCHLLVRGFRAASESEMKSLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLGLIAMLAVRVLAEQNVIPNVANVT 364
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Match: TENT5A (terminal nucleotidyltransferase 5A [Source:NCBI gene;Acc:101158475])

HSP 1 Score: 231.106 bits (588), Expect = 1.749e-69
Identity = 133/353 (37.68%), Postives = 205/353 (58.07%), Query Frame = 2 
Query:  374 YSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGT 1426
            + QV+RLDAIL ET  I G    P + +  +  +  V+ ++E+ +  + D+RLNG  A+ +L       + D+D++   D       +  F      VL+ + D L   +        + K +Y+ K+V++   N+ D WSL+ L  +     R + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S     + F+PT+   S + ++S+AL+HL ++ I T  PE IRGGGLLKYC LLV+ F     S++  L+RYMCSRFFID+ D+  Q + + SYLQNHF  L+D +  +L TL  V+++S++CLM  ER+QTL LI  +A+ + +  +  PN  + T
Sbjct:   29 WDQVQRLDAILTETIPIHGRGNFPTLQMQPRQIVKVVRSRMEEKRIHVRDVRLNGSAASHILHDDSGLGFKDLDLIFCADMK----GESEFQTVKDIVLDCLLDFLPDCVNKEKITPLTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----RGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYEC------SENPMTETFHPTIMGESVYGDISEALDHLRHKIICTRNPEEIRGGGLLKYCHLLVRGFRAASESEMKSLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLGLIAMLAVRVLAEQNVIPNVANVT 364
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Match: tent5ab (putative nucleotidyltransferase FAM46A [Source:NCBI gene;Acc:101158158])

HSP 1 Score: 230.335 bits (586), Expect = 3.819e-69
Identity = 139/380 (36.58%), Postives = 213/380 (56.05%), Query Frame = 2 
Query:  314 MMTATDCRSSDSESKN-----SVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHF-QLDDSQ-PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEF 1432
            M  + +C S+DS         SVL + QV+RLD IL  +  I G    P + V  +D +  V+ ++E+ +  + ++RLNG  A+ VL       + D+D++   +       ++ F    + VL+ + D     +        + K +Y+ K+V++   N+ D WSL+ L  +     R + ++LKF   ++RQFEFS+DSFQI LDSLL+FYE       S+  T   F+PT+   S + +   AL+HL  R I T  PE IRGGGLLKYC LLV+ F     +++  L+RYMCSRFFID+ D+  Q + + SYL NHF  L+D +  +L TL  V+ +S++CLM  ER+QTL LI  +A+ + +  +A PN  + T F
Sbjct:    1 MDESVECASTDSGPDGDSISLSVLNWEQVQRLDTILTSSIPIHGRWSFPTLEVKPRDIVKVVRSRMEEKRIHVREVRLNGSAASYVLHEDSGLGWKDLDLIFCAEL----KGEMEFQIVKELVLDSLLDFFPEGVNKEKITPVTLKEAYVQKMVKV--CNDSDRWSLISLSNN-----RGKNVELKFVDSLRRQFEFSVDSFQIRLDSLLLFYECSEH---SMAAT---FHPTILGESVYGDFPTALDHLRKRLICTRSPEEIRGGGLLKYCHLLVRGFRAASDTEMKLLQRYMCSRFFIDFPDVNEQRRKLESYLHNHFVDLEDRKYDYLATLYEVVQESTVCLMGHERRQTLSLISSLALRVLAEQNAIPNAANVTCF 363
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Match: SMESG000003588.1 (SMESG000003588.1)

HSP 1 Score: 863.218 bits (2229), Expect = 0.000e+0
Identity = 418/418 (100.00%), Postives = 418/418 (100.00%), Query Frame = 2 
Query:  311 MMMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY 1564
            MMMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY
Sbjct:    1 MMMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY 418
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Match: SMESG000003588.1 (SMESG000003588.1)

HSP 1 Score: 858.596 bits (2217), Expect = 0.000e+0
Identity = 416/416 (100.00%), Postives = 416/416 (100.00%), Query Frame = 2 
Query:  317 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY 1564
            MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY
Sbjct:    1 MTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIEMPDY 416
[Close]
BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Match: SMESG000041951.1 (SMESG000041951.1)

HSP 1 Score: 251.136 bits (640), Expect = 3.267e-77
Identity = 160/427 (37.47%), Postives = 240/427 (56.21%), Query Frame = 2 
Query:  311 MMMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGD-SRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKL--SYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ---PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFE-------WSIDKVTYADQVDLSTCKYRSYSTISSQWSTPSDMSPIE 1552
            M  TA       S+++  +L Y Q+ +L  +L +   +  +   LP I + +K F+  ++   +     + D+RLNGG A+ V+   Q + YND+D++I LD            +    + ++ S +L  +L     +  ++ +  SYIHK VR+Q+S +GD WSL+ LG+S  +G  +R ++LK  + M+R+FEFS+DSFQI LDSLL F++     S        +FYPTV   S W +  +A +HL  R I+T +PE IRGGGLLKYCKLL+++++  +   V  LERYMCSRFFID+ D++ Q   + SYL NHF  DDS+    +L+TL+ V+S+S++CLMN ER QTL LI+ I      +YD      +    E       W++D V Y     LS   +   S  +S   TPSD SP E
Sbjct:    1 MSYTAKGNLKKISKNRYQILPYDQICKLQEVLEQKVSLASNIPGLPTIRINLKLFLQQIRKNFDALDVKIEDMRLNGGAASYVIGSDQSFSYNDLDLIISLD----------MKNGTDEMPKIRSAVLNSILRNNRQSCHNKIIPESYIHKQVRVQDSFSGDFWSLISLGSS--YG-GNRIVELKLVYNMRRKFEFSVDSFQIKLDSLLTFFDKGYEISC-------HFYPTVVAESVWGSFHEAKSHLEQRLIMTEKPEEIRGGGLLKYCKLLIEDYAPHNDLDVVSLERYMCSRFFIDFPDVEKQKHKLLSYLINHFP-DDSKIRVNYLQTLEVVVSNSTVCLMNHERYQTLSLINNI------IYDVWNRAQTPLHIEIFNDPEQWALDHVFYGTSCCLSP-NHGMLSCPTSVIHTPSDHSPTE 399
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BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Match: SMESG000078143.1 (SMESG000078143.1)

HSP 1 Score: 189.889 bits (481), Expect = 3.393e-54
Identity = 133/384 (34.64%), Postives = 210/384 (54.69%), Query Frame = 2 
Query:  335 RSSDSESKNSVLKYSQVRRLDAILNETFVI-CGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLVRIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSV-PDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ--PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEFE----WSIDKVTYA 1462
            R   S+++  ++KY Q+ +L  +LN+  +I C       + +T+ + I+ +K  LE     + DIRL GG A+ V+     + YNDID++  +D     N D+  N    +V   I +L+        S    ++  YI K V IQ+    D WSL  LG        +  ++LKF    +RQ+E S+DSFQIVLD  L F   + + ++   C     YP V V S W ++ DAL HL N++I+   PE IRGGGLLKYCKLLV  F   PDL +   +++YMCSRFFID+  L +QH  I SY+ NHFQ +      FL  L  ++++SS+  ++ +R ++++LI+ +  +I +  ++ P + S  +F+    WS+ ++ Y 
Sbjct:    4 RRRGSKNQLQIMKYEQIVKLFKLLNDDLIISCEIDSEQSLVLTLTEIIIEMKEVLEKEDISIKDIRLIGGAASHVIAYNHDFPYNDIDVVFSIDSC--TNLDV-MNKIRSSVFSAIGNLISKSDHLQQSDLYPER--YIKKQVCIQSPKAKDYWSLFSLGCVT--NNNNNIVELKFASSTERQYECSVDSFQIVLDPALHF---ILQHNTVARC----LYPIVVVESTWGSIKDALQHLYNKHIVLEYPEQIRGGGLLKYCKLLVNGFQPHPDLDE-NSVKKYMCSRFFIDFPFLTNQHAKIVSYMTNHFQPNHELYISFLNHLADIVANSSV-YIDIDRLRSVFLINSLIQQIWT--ESLP-KISLVQFDDRKKWSVGEIVYG 368
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BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Match: SMESG000016756.1 (SMESG000016756.1)

HSP 1 Score: 184.882 bits (468), Expect = 2.910e-51
Identity = 126/386 (32.64%), Postives = 194/386 (50.26%), Query Frame = 2 
Query:  365 VLKYSQVRRLDAILNETFVI--CGDSRLPIICVTIKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIILDGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQ--------KLSYIHKLVRI--QNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQIVLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRYIITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYIDLKSQHKAIFSYLQNHFQLDDSQ-----PFLETLKRVISDSSICLMNQERQQTLYLIDQIAMEISSLYDAHPNEGSGTEF---EWSIDKVTYA 1462
            VL Y QV+RL  ++ +   +     S LP+I V+++  +  +K KL++    + D+RL+G  A  +L+      + +++++  +    M +     N     +  ++ DLL+  L     + K          K +YI K+ R+     +N D WSL+ LG        +  ++LKF  +MKRQ+EF+IDSFQIVLD++L FY  V + SS       N +PTV   S   +  +A  HL    I T  PE I GGGLLKYC LL   F       +   E+YMCSRFFIDY D+  Q + + S+L +   L DS        L  L  V+S S++CLM  ER+QTL +I+ ++  I S  +   +     +     W +D+V Y 
Sbjct:   68 VLSYEQVKRLHRVIEKPLKLKPVSHSVLPVIEVSLRALLGEIKRKLKEVDVVIKDVRLDGTAAGCILNLNPNDDFRELNVIFTVSLHDMTSMQKIKN----TIFSLLIDLLKKTLNSKPESLKHNFLINEELIKDNYIQKMTRVLCNQESNSDCWSLISLGT---LEIGNETVELKFIDKMKRQYEFTIDSFQIVLDTMLAFY-TVSKCSS----ITPNLFPTVVAESVSGSFQEAFKHLKENIISTKNPEEILGGGLLKYCGLLAVGFQQNSAMDIRATEKYMCSRFFIDYPDINVQRQKLESFLDS---LVDSNYEIKINLLNVLYEVVSHSTVCLMTHERRQTLQMINSLSQNILSEIEIKKSTVQLDDLSSQNWVLDQVFYG 438
The following BLAST results are available for this feature:
BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TENT5A2.830e-6736.48terminal nucleotidyltransferase 5A [Source:HGNC Sy... [more]
TENT5A6.478e-6736.48terminal nucleotidyltransferase 5A [Source:HGNC Sy... [more]
TENT5A1.889e-6636.48terminal nucleotidyltransferase 5A [Source:HGNC Sy... [more]
TENT5C8.575e-6537.93terminal nucleotidyltransferase 5C [Source:HGNC Sy... [more]
TENT5B1.742e-6439.04terminal nucleotidyltransferase 5B [Source:HGNC Sy... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pqn-441.060e-5433.33Prion-like-(Q/N-rich)-domain-bearing protein [Sou... [more]
pqn-441.060e-5433.33Prion-like-(Q/N-rich)-domain-bearing protein [Sou... [more]
pqn-441.583e-5433.33Prion-like-(Q/N-rich)-domain-bearing protein [Sou... [more]
pqn-442.070e-5433.33Prion-like-(Q/N-rich)-domain-bearing protein [Sou... [more]
pqn-442.260e-5433.33Prion-like-(Q/N-rich)-domain-bearing protein [Sou... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG463855.052e-7340.46gene:FBgn0286778 transcript:FBtr0474227[more]
CG463855.052e-7340.46gene:FBgn0286778 transcript:FBtr0474226[more]
CG463859.340e-7340.46gene:FBgn0286778 transcript:FBtr0474225[more]
CG463853.170e-7140.46gene:FBgn0286778 transcript:FBtr0474229[more]
CG463851.099e-7040.46gene:FBgn0286778 transcript:FBtr0474224[more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TENT5A1.145e-7237.56terminal nucleotidyltransferase 5Aa [Source:NCBI g... [more]
tent5ba4.476e-7039.03terminal nucleotidyltransferase 5ba [Source:ZFIN;A... [more]
tent5ab6.945e-6937.08terminal nucleotidyltransferase 5Ab [Source:ZFIN;A... [more]
tent5ab6.945e-6937.08terminal nucleotidyltransferase 5Ab [Source:ZFIN;A... [more]
tent5bb3.039e-6737.15terminal nucleotidyltransferase 5Bb [Source:ZFIN;A... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
TENT5A6.330e-7135.82terminal nucleotidyltransferase 5A [Source:NCBI ge... [more]
tent5b1.457e-6836.61terminal nucleotidyltransferase 5B [Source:NCBI ge... [more]
ttk3.389e-6637.08TTK protein kinase [Source:Xenbase;Acc:XB-GENE-953... [more]
TENT5D9.672e-6035.01terminal nucleotidyltransferase 5D [Source:HGNC Sy... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tent5a2.154e-6836.73terminal nucleotidyltransferase 5A [Source:MGI Sym... [more]
Tent5a4.691e-6836.73terminal nucleotidyltransferase 5A [Source:MGI Sym... [more]
Tent5c3.776e-6638.16terminal nucleotidyltransferase 5C [Source:MGI Sym... [more]
Tent5b2.709e-6338.08terminal nucleotidyltransferase 5B [Source:MGI Sym... [more]
Tent5d2.802e-6236.81terminal nucleotidyltransferase 5D [Source:MGI Sym... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96IP4|TET5A_HUMAN1.359e-6636.48Terminal nucleotidyltransferase 5A OS=Homo sapiens... [more]
sp|Q29RH2|TET5B_BOVIN4.008e-6638.48Terminal nucleotidyltransferase 5B OS=Bos taurus O... [more]
sp|Q5XIV0|TET5C_RAT6.406e-6638.72Terminal nucleotidyltransferase 5C OS=Rattus norve... [more]
sp|Q7ZUP1|TET5C_DANRE2.058e-6537.08Terminal nucleotidyltransferase 5C OS=Danio rerio ... [more]
sp|Q5SSF7|TET5C_MOUSE2.641e-6538.16Terminal nucleotidyltransferase 5C OS=Mus musculus... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1K5N91.555e-7943.48Uncharacterized protein OS=Tetranychus urticae OX=... [more]
A0A087TQV38.394e-7841.69Protein FAM46C (Fragment) OS=Stegodyphus mimosarum... [more]
A0A4Y2FPK58.925e-7841.69Nucleotidyltransferase FAM46C OS=Araneus ventricos... [more]
A0A0K8TR873.707e-7743.30Uncharacterized protein OS=Tabanus bromius OX=3042... [more]
A0A5B7HSN01.889e-7642.73Protein FAM46C OS=Portunus trituberculatus OX=2104... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tent5ab3.770e-7036.93protein FAM46A-like [Source:NCBI gene;Acc:10304232... [more]
tent5bb4.981e-6937.33protein FAM46A-like [Source:NCBI gene;Acc:10303698... [more]
tent5c1.975e-6837.92terminal nucleotidyltransferase 5C [Source:NCBI ge... [more]
TENT5A6.388e-6635.90terminal nucleotidyltransferase 5A [Source:HGNC Sy... [more]
tent5ba5.711e-6436.86protein FAM46A-like [Source:NCBI gene;Acc:10304678... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tent5ab1.813e-2933.95terminal nucleotidyltransferase 5Ab [Source:ZFIN;A... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO302952.715e-7339.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tent5bb1.081e-7237.60putative nucleotidyltransferase FAM46A [Source:NCB... [more]
tent5ba1.127e-7038.16terminal nucleotidyltransferase 5B [Source:NCBI ge... [more]
TENT5A1.749e-6937.68terminal nucleotidyltransferase 5A [Source:NCBI ge... [more]
TENT5A1.749e-6937.68terminal nucleotidyltransferase 5A [Source:NCBI ge... [more]
tent5ab3.819e-6936.58putative nucleotidyltransferase FAM46A [Source:NCB... [more]
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BLAST of Nucleotidyltransferase FAM46C vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000003588.10.000e+0100.00SMESG000003588.1[more]
SMESG000003588.10.000e+0100.00SMESG000003588.1[more]
SMESG000041951.13.267e-7737.47SMESG000041951.1[more]
SMESG000078143.13.393e-5434.64SMESG000078143.1[more]
SMESG000016756.12.910e-5132.64SMESG000016756.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30032022 ID=SMED30032022|Name=Nucleotidyltransferase FAM46C|organism=Schmidtea mediterranea sexual|type=transcript|length=1781bp
CAAAATTTCATAATTTATTTATTTATTAATGAATTCTCTGAAAATCTATT
TTTAAGACATTATTAGAATGAGCGTAGATTGGTAGTTACATTGGTAGATT
GCCATTAATCGATAGCTCCTGACATGTGTTTGTGTGCATGAAATGAAGCT
AGTCAGATGAGCCGGCACACACTCACAGCTAATAGAAAATTCCAATGACG
TCACGAATTCGACCAATCGAAATTAATCGTTTTCCAATCAATGAATATCA
TAATGAATATCAGTAGTAAGTAATTTGTAAGTAAACTAATTCCTTATTTA
CTGTAACACCATGATGATGACTGCTACTGATTGTAGAAGTTCTGATAGCG
AATCTAAGAATAGTGTATTAAAGTATAGTCAAGTTCGTAGACTAGATGCT
ATCTTGAATGAGACATTCGTTATTTGTGGAGATAGCAGATTGCCCATCAT
TTGCGTTACGATAAAGGATTTTATTTTAGCTGTTAAACACAAATTGGAGG
ATTATCAGTTTCCCATGGTAGACATTCGGCTTAATGGTGGAGGAGCAGCA
GCTGTTCTCGATCCTCTTCAGTTATATAAATACAACGATATTGACATTCT
CATCATTCTCGACGGTTCTCACATGGATAACGATGACATCTATTTCAATG
ACACAATCAAAGCAGTTCTTGAAGTGATCAGTGACCTTCTGCAACCGATG
CTGGAGCCGACAGCGAGCGCGTTCAAATCTCAGAAGTTGTCTTACATTCA
CAAGTTAGTTCGAATCCAGAACTCAAACAACGGCGACAGTTGGTCACTGT
TGGGACTCGGTGCTAGCGGCCGATTTGGCTACCGGTCGAGGAGAATCGAT
TTGAAATTCACCCACCGAATGAAACGGCAATTCGAGTTCTCCATCGATTC
CTTTCAAATCGTTCTCGACAGTCTGTTGATATTCTACGAAGCCGTTCGTC
GGTTTTCCTCATCTGTTGTGTGCACGAATAAAAACTTCTATCCAACCGTT
TCGGTCATTTCAAAATGGCCGAATCTCTCGGACGCTTTAAATCATCTTGG
AAACCGTTACATAATCACCTCGCAACCAGAGCACATTCGAGGCGGCGGCC
TCTTGAAATACTGCAAACTCCTCGTGCAGAATTTCTCTGTGCCCGATCTG
TCAAAGGTCGCCAAACTCGAGCGCTACATGTGTTCTCGGTTCTTCATTGA
CTACATCGATTTGAAGTCTCAACACAAAGCGATTTTCAGCTACTTGCAAA
ATCATTTCCAACTCGACGACTCCCAGCCGTTCTTGGAGACCTTGAAGCGA
GTCATATCGGATTCATCTATTTGTCTGATGAATCAAGAAAGGCAGCAAAC
TCTCTATTTGATAGATCAGATCGCTATGGAAATCAGTTCTCTTTACGATG
CGCATCCGAACGAAGGTTCCGGAACCGAATTCGAGTGGAGCATCGACAAG
GTGACATATGCCGACCAAGTCGACTTGTCAACTTGTAAATATCGCTCTTA
TTCAACCATAAGCAGCCAATGGAGCACCCCGTCCGACATGAGCCCCATTG
AAATGCCGGATTATTAGGCAAATCAATCCTCCGTCCGGCTCATTACCGTC
TCTTCTGATCTCGAATATCCATGGAACTACTTAAACGCAATTTAAGAAAA
TGGCGCTTTGTTTTTATGTGGTTGTGGTCCATTTTGTAAAGTCTTCAAAG
ATTTCCTATGCGATAATTATACAACTATTTTATTAATTGCTTTTTATTTA
ATAATTATCATTATTTTTATTACCAAAAAAA
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protein sequence of SMED30032022-orf-1

>SMED30032022-orf-1 ID=SMED30032022-orf-1|Name=SMED30032022-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=419bp
MMMTATDCRSSDSESKNSVLKYSQVRRLDAILNETFVICGDSRLPIICVT
IKDFILAVKHKLEDYQFPMVDIRLNGGGAAAVLDPLQLYKYNDIDILIIL
DGSHMDNDDIYFNDTIKAVLEVISDLLQPMLEPTASAFKSQKLSYIHKLV
RIQNSNNGDSWSLLGLGASGRFGYRSRRIDLKFTHRMKRQFEFSIDSFQI
VLDSLLIFYEAVRRFSSSVVCTNKNFYPTVSVISKWPNLSDALNHLGNRY
IITSQPEHIRGGGLLKYCKLLVQNFSVPDLSKVAKLERYMCSRFFIDYID
LKSQHKAIFSYLQNHFQLDDSQPFLETLKRVISDSSICLMNQERQQTLYL
IDQIAMEISSLYDAHPNEGSGTEFEWSIDKVTYADQVDLSTCKYRSYSTI
SSQWSTPSDMSPIEMPDY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity
GO:1990817RNA adenylyltransferase activity
GO:0003674molecular_function
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR012937TET5
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR012937Terminal nucleotidyltransferaseSMARTSM01153DUF1693_2coord: 1..271
e-value: 2.9E-47
score: 173.0
IPR012937Terminal nucleotidyltransferasePFAMPF07984NTP_transf_7coord: 6..270
e-value: 1.4E-78
score: 264.3
IPR012937Terminal nucleotidyltransferasePANTHERPTHR12974PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44coord: 7..288
NoneNo IPR availablePANTHERPTHR12974:SF36PRION-LIKE-(Q/N-RICH)-DOMAIN-BEARING PROTEINcoord: 7..288